BLAST2 result
BLASTP 2.2.2 [Dec-14-2001]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= AC146570.7 - phase: 0
(915 letters)
Database: sprot
164,201 sequences; 59,974,054 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
USO1_YEAST (P25386) Intracellular protein transport protein USO1 70 3e-11
MLP1_YEAST (Q02455) MLP1 protein (Myosin-like protein 1) 65 6e-10
NUF1_YEAST (P32380) NUF1 protein (Spindle poly body spacer prote... 65 1e-09
RA50_ARCFU (O29230) DNA double-strand break repair rad50 ATPase 64 1e-09
RA50_METMP (P62134) DNA double-strand break repair rad50 ATPase 63 3e-09
MYS3_HYDAT (P39922) Myosin heavy chain, clone 203 (Fragment) 63 3e-09
SMC2_XENLA (P50533) Structural maintenance of chromosome 2 (Chro... 63 4e-09
REST_CHICK (O42184) Restin (Cytoplasmic linker protein-170) (CLI... 62 7e-09
MYH8_HUMAN (P13535) Myosin heavy chain, skeletal muscle, perinat... 61 1e-08
TPM1_HYDAT (P39921) Tropomyosin I 61 2e-08
MEDB_GIALA (Q08014) Median body protein 61 2e-08
TMF1_HUMAN (P82094) TATA element modulatory factor (TMF) 60 3e-08
RA50_SULTO (Q96YR5) DNA double-strand break repair rad50 ATPase 60 3e-08
RA50_SULSO (Q97WH0) DNA double-strand break repair rad50 ATPase 60 3e-08
MYS2_DICDI (P08799) Myosin II heavy chain, non muscle 60 3e-08
EEA1_HUMAN (Q15075) Early endosome antigen 1 (Endosome-associate... 60 3e-08
CENF_HUMAN (P49454) CENP-F kinetochore protein (Centromere prote... 60 3e-08
ERC1_HUMAN (Q8IUD2) ERC protein 1 (ELKS protein) 59 5e-08
RA50_AQUAE (O67124) Probable DNA double-strand break repair rad5... 59 6e-08
MYHD_HUMAN (Q9UKX3) Myosin heavy chain, skeletal muscle, extraoc... 59 6e-08
>USO1_YEAST (P25386) Intracellular protein transport protein USO1
Length = 1790
Score = 69.7 bits (169), Expect = 3e-11
Identities = 125/604 (20%), Positives = 249/604 (40%), Gaps = 65/604 (10%)
Query: 4 IMNLANDFDDEILSEFESLLSEQTDFPLLSEKTDDSK---KHGGNETEMAKNGSDSEIEW 60
I N +++EI + + S Q + + +K D+ + K + +E N SEI+
Sbjct: 1168 IANKERQYNEEISQLNDEITSTQQENESIKKKNDELEGEVKAMKSTSEEQSNLKKSEIDA 1227
Query: 61 LRNVVEELEEREMKLQSELLE-YYSLKEQVPVIEEFQRQLRIKSVEIDMLHMTIKSLQEE 119
L ++EL+++ ++ LLE S++ + I+E Q + K E+ L +K+ +++
Sbjct: 1228 LNLQIKELKKKNETNEASLLESIKSVESETVKIKELQDECNFKEKEVSELEDKLKASEDK 1287
Query: 120 NNKLQEELIHEASAKRELEVARNKIKELQRQIKIIANQTK------GQLLLLKQKVSGLQ 173
N+K E K EL+ K EL+ Q++ I N +K +L LK+ S +
Sbjct: 1288 NSKYLELQKESEKIKEELDA---KTTELKIQLEKITNLSKAKEKSESELSRLKKTSSEER 1344
Query: 174 AKEEEVVKKDAEIENNLKTVND-FEIEKKL-------------KTVNDLEIEAVGLKRRN 219
EE ++K ++N ++ N FE E+KL + +N LE E + L+ N
Sbjct: 1345 KNAEEQLEK---LKNEIQIKNQAFEKERKLLNEGSSTITQEYSEKINTLEDELIRLQNEN 1401
Query: 220 ----KELQHEKRELTVKLNAAESRITELSSVTENEMIADAKSETGRLRHANEDLQKQVEG 275
KE+ + + EL K++ + + E T + + S ++ +E L
Sbjct: 1402 ELKAKEIDNTRSELE-KVSLSNDELLEEKQNTIKSLQDEILSYKDKITRNDEKLLSIERD 1460
Query: 276 LQMNRFSEVEELVYLRWVNACLRYELRNYKAPSGKSLARDLNNSFNPKSQEKAKQLMLEY 335
+ + S E+L + A + L+ + S K A EK+K++M +
Sbjct: 1461 NKRDLESLKEQLRAAQESKAKVEEGLKKLEEESSKEKA----------ELEKSKEMMKKL 1510
Query: 336 AGSERGHGDTDIESNFSHDHSSPGSEDLDNAYINSPTYKYSNLSKKTSLIQKLKKWNKNN 395
+ + +T+++S+ S E L+ + ++ + +K+ LI ++ + K
Sbjct: 1511 ESTIESN-ETELKSSMETIRKS--DEKLEQSKKSAEEDIKNLQHEKSDLISRINESEK-- 1565
Query: 396 DSSAFSSPARSLSIGSPCRVSTSYRPRNTLESLMLRNAHDAVAITTFEQKEHK------- 448
D S R + + N E + + + V + E E +
Sbjct: 1566 DIEELKSKLRIEAKSGSELETVKQELNNAQEKIRINAEENTVLKSKLEDIERELKDKQAE 1625
Query: 449 -PTHSPETPFLPSLRKVSSSDDILDSVSASFQLMSKSVDRSLDEKYPAYK-DLHKLALAR 506
++ E L S ++ + LDS Q S+ R+ K+ K L + A+
Sbjct: 1626 IKSNQEEKELLTS--RLKELEQELDSTQQKAQ-KSEEERRAEVRKFQVEKSQLDEKAMLL 1682
Query: 507 EKQLKEKAEKARGEKFGDNSNLNTTKAEEERSTSLDSELTQVNEKACVSDGLNKQSEDVK 566
E + + K + K +++ TT ++ + L EL + + + L + +ED
Sbjct: 1683 ETKYNDLVNKEQAWKRDEDTVKKTTDSQRQEIEKLAKELDNLKAE---NSKLKEANEDRS 1739
Query: 567 DFDN 570
+ D+
Sbjct: 1740 EIDD 1743
Score = 64.3 bits (155), Expect = 1e-09
Identities = 126/616 (20%), Positives = 245/616 (39%), Gaps = 82/616 (13%)
Query: 13 DEILSEFESLLSE-QTDFPLLSEKTDDSKKHGGNETEMAKNGSDSEIEWLRNVVEELEER 71
+EI+S+ +S E ++ LL EK E A +D + N + EL +
Sbjct: 1039 EEIISKSDSSKDEYESQISLLKEKL-----------ETATTANDENV----NKISELTKT 1083
Query: 72 EMKLQSELLEYYSLKEQVPVIEEFQRQLRIKSVEIDMLHMTIKSLQ------EENNKLQE 125
+L++EL Y +LK ++ E + +K V+ + H+ + +Q E +L
Sbjct: 1084 REELEAELAAYKNLKNELETKLETSEKA-LKEVKENEEHLKEEKIQLEKEATETKQQLNS 1142
Query: 126 ELIHEASAKRELEVARNKIKELQRQIKIIANQTKGQLLLLKQKVSGLQAKEEEVVKKDAE 185
+ S ++E E ++K+ + QI Q ++ L +++ Q + E + KK+ E
Sbjct: 1143 LRANLESLEKEHEDLAAQLKKYEEQIANKERQYNEEISQLNDEITSTQQENESIKKKNDE 1202
Query: 186 IENNLKTVNDFEIEK---KLKTVNDLEIEAVGLKRRN-----------KELQHEK---RE 228
+E +K + E+ K ++ L ++ LK++N K ++ E +E
Sbjct: 1203 LEGEVKAMKSTSEEQSNLKKSEIDALNLQIKELKKKNETNEASLLESIKSVESETVKIKE 1262
Query: 229 LTVKLNAAESRITELSSVTENEMIADAKSETGRLRHANEDLQKQVEGLQMNRFSEVEELV 288
L + N E ++EL + + D S+ L+ +E ++++++ ++E++
Sbjct: 1263 LQDECNFKEKEVSELED--KLKASEDKNSKYLELQKESEKIKEELDAKTTELKIQLEKIT 1320
Query: 289 YLRWVNACLRYELRNYKAPS------GKSLARDLNNSFNPKSQEKAKQLMLEYAGSERGH 342
L EL K S + L N K+Q K+ L GS
Sbjct: 1321 NLSKAKEKSESELSRLKKTSSEERKNAEEQLEKLKNEIQIKNQAFEKERKLLNEGSSTIT 1380
Query: 343 GDTDIESNFSHD-------HSSPGSEDLDNAYINSPTYKYSN---LSKKTSLIQKLKKWN 392
+ + N D + ++++DN SN L +K + I+ L+
Sbjct: 1381 QEYSEKINTLEDELIRLQNENELKAKEIDNTRSELEKVSLSNDELLEEKQNTIKSLQDEI 1440
Query: 393 KNNDSSAFSSPARSLSIGSPCRVSTSYRPRNTLESL--MLRNAHDAVAITTFEQKEHKPT 450
+ + + LSI + LESL LR A ++ A K+ +
Sbjct: 1441 LSYKDKITRNDEKLLSI--------ERDNKRDLESLKEQLRAAQESKAKVEEGLKKLEEE 1492
Query: 451 HSPETPFLPSLRKVSSS-DDILDSVSASFQLMSKSVDRSLDEKYPAYKDLHKLALAREKQ 509
S E L +++ + ++S + +++ +S DEK K K
Sbjct: 1493 SSKEKAELEKSKEMMKKLESTIESNETELKSSMETIRKS-DEKLEQSK----------KS 1541
Query: 510 LKEKAEKARGEKFGDNSNLNTTKAE-EERSTSLDSELTQVNEKACVSDGLNKQSEDVK-D 567
+E + + EK S +N ++ + EE + L E +E V LN E ++ +
Sbjct: 1542 AEEDIKNLQHEKSDLISRINESEKDIEELKSKLRIEAKSGSELETVKQELNNAQEKIRIN 1601
Query: 568 FDNQTITEMKLFKIEK 583
+ T+ + KL IE+
Sbjct: 1602 AEENTVLKSKLEDIER 1617
Score = 57.4 bits (137), Expect = 2e-07
Identities = 165/792 (20%), Positives = 303/792 (37%), Gaps = 127/792 (16%)
Query: 32 LSEKTDDSKKHGGNETEMAKNGSDSEIEWLRNVVEELEEREMKLQSELL----EYYSLKE 87
L ++ D S + ET+ K ++I ++ + E LEE MK+Q L E+ S KE
Sbjct: 886 LQKEKDKSNVNHQKETKSLKEDIAAKITEIKAINENLEE--MKIQCNNLSKEKEHIS-KE 942
Query: 88 QVPVIEEFQRQ--LRIKSVE-IDMLHMTIKSLQEENNKL---QEELIHEASAKRELEVAR 141
V FQ L K E + L K +Q EN L EE +E+S +L +
Sbjct: 943 LVEYKSRFQSHDNLVAKLTEKLKSLANNYKDMQAENESLIKAVEESKNESSI--QLSNLQ 1000
Query: 142 NKIKELQRQ---IKIIANQTKGQLLLLKQKVSGLQAKEEEVVKKDA----EIENNLK--- 191
NKI + ++ +I + + LK+ +S L+ +EE++ K E E+ +
Sbjct: 1001 NKIDSMSQEKENFQIERGSIEKNIEQLKKTISDLEQTKEEIISKSDSSKDEYESQISLLK 1060
Query: 192 -------TVNDFEIEK---KLKTVNDLEIEAVGLKRRNKELQHEKRELTVKLNAAESRIT 241
T ND + K KT +LE E K + K EL KL +E +
Sbjct: 1061 EKLETATTANDENVNKISELTKTREELEAELAAYK-------NLKNELETKLETSEKALK 1113
Query: 242 ELSSVTEN---------EMIADAKSETGRLRHANEDLQKQVEGL--QMNRFSE------- 283
E+ E+ + + K + LR E L+K+ E L Q+ ++ E
Sbjct: 1114 EVKENEEHLKEEKIQLEKEATETKQQLNSLRANLESLEKEHEDLAAQLKKYEEQIANKER 1173
Query: 284 ----------------VEELVYLRWVNACLRYELRNYKAPSGK--SLARDLNNSFN---- 321
+E ++ N L E++ K+ S + +L + ++ N
Sbjct: 1174 QYNEEISQLNDEITSTQQENESIKKKNDELEGEVKAMKSTSEEQSNLKKSEIDALNLQIK 1233
Query: 322 --PKSQEKAKQLMLEYAGSERGH----GDTDIESNFSHDHSS------PGSEDLDNAYI- 368
K E + +LE S + E NF S SED ++ Y+
Sbjct: 1234 ELKKKNETNEASLLESIKSVESETVKIKELQDECNFKEKEVSELEDKLKASEDKNSKYLE 1293
Query: 369 ---NSPTYKYSNLSKKTSLIQKLKKWNKNNDSSAFSSPARSLSIGSPCRVSTSYRPRNTL 425
S K +K T L +L+K ++ + +S S S + ++S +N
Sbjct: 1294 LQKESEKIKEELDAKTTELKIQLEK-----ITNLSKAKEKSESELSRLKKTSSEERKNAE 1348
Query: 426 ESLMLRNAHDAVAITTFEQKEHKPTHSPETPFLPSLRKVSSSDDILDSVSASFQLMSKSV 485
E L + FE++ T K+++ +D L + +L +K +
Sbjct: 1349 EQLEKLKNEIQIKNQAFEKERKLLNEGSSTITQEYSEKINTLEDELIRLQNENELKAKEI 1408
Query: 486 DRSLDEKYPAYKDLHKLALAREKQLKEKAEKARGEKFGDNSNLNTTKAEEERSTSLDSEL 545
D + E L K++L+ ++ L+EK NT K+ ++ S ++
Sbjct: 1409 DNTRSE-------LEKVSLSNDELLEEKQ--------------NTIKSLQDEILSYKDKI 1447
Query: 546 TQVNEKACVSDGLNKQSEDVKDFDNQTITEMKLFKIEKRPPRLPRPPPKPSDGAPVSNSL 605
T+ +EK + NK+ + + E K K+E+ +L K S +
Sbjct: 1448 TRNDEKLLSIERDNKRDLESLKEQLRAAQESKA-KVEEGLKKLEEESSKEKAELEKSKEM 1506
Query: 606 NEIPYAPSVPSPPPPPGSLPRGAVGDDKVKRAPELVEFYQSLMKREAKKDASLLTSSTSN 665
+ + + S+ D+K++++ + E ++ E S + S +
Sbjct: 1507 MKKLESTIESNETELKSSMETIRKSDEKLEQSKKSAEEDIKNLQHEKSDLISRINESEKD 1566
Query: 666 AADTRSNVIAEIENRSSFLLAVKADVETQGDFVMSLATEVRAASFSKIEDVVAFVNWLDE 725
+ +S + E ++ S L VK ++ + + + E SK+ED+ +
Sbjct: 1567 IEELKSKLRIEAKSGSE-LETVKQELNNAQEKI-RINAEENTVLKSKLEDIERELKDKQA 1624
Query: 726 ELSFLSDERAVL 737
E+ +E+ +L
Sbjct: 1625 EIKSNQEEKELL 1636
Score = 51.6 bits (122), Expect = 9e-06
Identities = 56/245 (22%), Positives = 111/245 (44%), Gaps = 31/245 (12%)
Query: 34 EKTDDSKKHGGNETEMAKNGSDSEIEWLRNVVEELEEREMKLQSELLEYYSLKEQVPVIE 93
EK + SKK + + ++ I + +++EE + KL+ E L+ +
Sbjct: 1533 EKLEQSKKSAEEDIKNLQHEKSDLISRINESEKDIEELKSKLRIEAKSGSELETVKQELN 1592
Query: 94 EFQRQLRIKSVEIDMLHMTIKSLQEENNKLQEELIHEASAKRELEVARNKIKELQRQIKI 153
Q ++RI + E +L ++ ++ E Q E+ S + E E+ +++KEL++++
Sbjct: 1593 NAQEKIRINAEENTVLKSKLEDIERELKDKQAEI---KSNQEEKELLTSRLKELEQELD- 1648
Query: 154 IANQTKGQLLLLKQKVSGLQAKEEEVVKKDAEIENNLKTVNDFEIEKKLKTVNDLEIEAV 213
+ Q K Q K EE ++ AE V F++EK + +E
Sbjct: 1649 -STQQKAQ-------------KSEE--ERRAE-------VRKFQVEKSQLDEKAMLLETK 1685
Query: 214 GLKRRNKELQHEKRELTVKLNAAESRITELSSVTENEMIADAKSETGRLRHANEDLQKQV 273
NKE ++ E TVK +S+ E+ + + + + K+E +L+ ANED + ++
Sbjct: 1686 YNDLVNKEQAWKRDEDTVK-KTTDSQRQEIEKLAKE--LDNLKAENSKLKEANED-RSEI 1741
Query: 274 EGLQM 278
+ L +
Sbjct: 1742 DDLML 1746
Score = 43.9 bits (102), Expect = 0.002
Identities = 119/583 (20%), Positives = 225/583 (38%), Gaps = 84/583 (14%)
Query: 7 LANDFDDEILSE--FESLLSEQTDFPLLSEKTDDSKKHGGNETEMAKNGSDSEIEWLRNV 64
L++D D+E +S+ FE + Q L + + ETE ++ L N
Sbjct: 715 LSHDPDEEPISKISFEEVEKLQRQCTKLKGEITSLQ----TETESTHENLTEKLIALTNE 770
Query: 65 VEELEEREMKLQSELLEYYSLKEQVPVIEEFQRQLRIKSVEIDMLHMTIKSLQEENNKLQ 124
+EL+E+ L S + SLKE ++E + +R E+ L +++ +EN Q
Sbjct: 771 HKELDEKYQILNSS---HSSLKENFSILETELKNVRDSLDEMTQLRDVLETKDKEN---Q 824
Query: 125 EELIHEASAKRELEVARNKIKELQRQIKIIANQTKGQLLLLKQKVSGLQAKEEEVVKKDA 184
L+ S + E + IK L++ ++ I +Q KK A
Sbjct: 825 TALLEYKSTIHKQE---DSIKTLEKGLETILSQ-----------------------KKKA 858
Query: 185 EIENNLKTVNDFEIEKKLKTVNDLEIEAVGLKRRNKELQHEKRELTVKLNAAESRITELS 244
E N + F + ++++ V + + + ++ + H+K ++K + A ++ITE+
Sbjct: 859 EDGINKMGKDLFALSREMQAVEE-NCKNLQKEKDKSNVNHQKETKSLKEDIA-AKITEIK 916
Query: 245 SVTENEMIADAKSETGRLRHANEDLQKQVEGLQMNRFSEVEELVYLRWVNACLRYELRNY 304
++ EN + + K + L E + K++ + +RF + LV + L+ NY
Sbjct: 917 AINEN--LEEMKIQCNNLSKEKEHISKELVEYK-SRFQSHDNLV--AKLTEKLKSLANNY 971
Query: 305 K--APSGKSLARDLNNSFNPKS------QEKAKQLMLEYAGSERGHGDTDIESNFSHDHS 356
K +SL + + S N S Q K + E + G +
Sbjct: 972 KDMQAENESLIKAVEESKNESSIQLSNLQNKIDSMSQEKENFQIERGSIEKNIEQLKKTI 1031
Query: 357 SPGSEDLDNAYINSPTYKYSNLSKKTSLIQKLKKWNKNNDSSAFS-SPARSLSIGSPCRV 415
S + + S + K S+ + L +KL+ ND + S +
Sbjct: 1032 SDLEQTKEEIISKSDSSKDEYESQISLLKEKLETATTANDENVNKISELTKTREELEAEL 1091
Query: 416 STSYRPRNTLESLMLRNAHDAVAITTFEQKEHKPTHSPETPFLPSLRKVSSSDDILDSVS 475
+ +N LE+ L + A+ E KE++ E L ++ + + L+S+
Sbjct: 1092 AAYKNLKNELET-KLETSEKALK----EVKENEEHLKEEKIQLE--KEATETKQQLNSLR 1144
Query: 476 ASFQLMSKSVDRSLDEKYPAYKDLHKLALAREKQLKEKAEKARGEKFGDNSNLNTTKAEE 535
A+ + + K ++DL E+Q+ K + E N + +T+ E
Sbjct: 1145 ANLESLEKE-----------HEDLAAQLKKYEEQIANKERQYNEEISQLNDEITSTQQEN 1193
Query: 536 ERSTSLDSEL------------TQVNEKACVSDGLNKQSEDVK 566
E + EL Q N K D LN Q +++K
Sbjct: 1194 ESIKKKNDELEGEVKAMKSTSEEQSNLKKSEIDALNLQIKELK 1236
>MLP1_YEAST (Q02455) MLP1 protein (Myosin-like protein 1)
Length = 1875
Score = 65.5 bits (158), Expect = 6e-10
Identities = 123/621 (19%), Positives = 241/621 (38%), Gaps = 104/621 (16%)
Query: 14 EILSEFESLLSEQTDFPLLSEKTDDSKKHGGNETEMAKNGSDSEIEWLRNVVEELEEREM 73
+IL + E L S +D+ L + ++ K+ N+ + R E L+ ++
Sbjct: 1288 DILEKHEQLSS--SDYEKLESEIENLKEELENKERQGAEAEEKFNRLRRQAQERLKTSKL 1345
Query: 74 KLQSELLEYYSLKEQVPVIEEFQRQLRIKSVEIDMLHMTIKSLQ-EENNKLQEELIHEAS 132
S + SL++ V+E + + E+ + + Q E KLQE+
Sbjct: 1346 SQDSLTEQVNSLRDAKNVLENSLSEANARIEELQNAKVAQGNNQLEAIRKLQEDA---EK 1402
Query: 133 AKRELEVARNKIKELQRQIKIIANQTKGQLLLLKQKVSGLQAKEEEVVKKDAEIENNLKT 192
A REL+ K++E + N ++ LK+++ + ++++ A +N+L
Sbjct: 1403 ASRELQA---KLEESTTSYESTINGLNEEITTLKEEIEKQRQIQQQLQATSANEQNDLSN 1459
Query: 193 VNDFEIEKKLKTVNDLEIEAVGLKRRNKELQHEKRELTVKLNAAESRITELSSVTENEMI 252
+ +E K+ + +I K ++ + +E+ K+ A+ R+ + S++ E+
Sbjct: 1460 I----VESMKKSFEEDKI---------KFIKEKTQEVNEKILEAQERLNQPSNINMEEIK 1506
Query: 253 ADAKSE-----TGRLRHANEDLQKQV----------------EGLQMNRFSEVEELVYLR 291
+SE + ++R A E L+K++ E L+ +VEE +
Sbjct: 1507 KKWESEHEQEVSQKIREAEEALKKRIRLPTEEKINKIIERKKEELEKEFEEKVEERIKSM 1566
Query: 292 WVNACLRYELRNYKAPSGKSLARDLNNSFNPKSQEKAKQL--MLEYAGSERGHGDTDIES 349
+ + LR + ++L N +N K QE+ K + + ER +IES
Sbjct: 1567 EQSGEIDVVLRKQLEAKVQEKQKELENEYNKKLQEELKDVPHSSHISDDERDKLRAEIES 1626
Query: 350 ----NFSHDHSSPGSEDLDNAYINSPTYKYSNLSKKTSLIQKLKKWNK--NNDSSAFSSP 403
F+++ + + D K + K T L +KL K + + SP
Sbjct: 1627 RLREEFNNELQAIKKKSFDEG-------KQQAMMKTTLLERKLAKMESQLSETKQSAESP 1679
Query: 404 ARSLS------IGSPCRV----STSYRPRNTLESLMLRNA-------------------- 433
+S++ +G P ++ ++ + P + E L+ N+
Sbjct: 1680 PKSVNNVQNPLLGLPRKIEENSNSPFNPLLSGEKLLKLNSKSSSGGFNPFTSPSPNKHLQ 1739
Query: 434 HDAVAITTFEQKEHKPTHSPETPFLPSLRKVSSSDDILDSVSASFQLMSKSVDRSLDEKY 493
+D + K PTH + +P+ R + +S+S L + + D L
Sbjct: 1740 NDNDKRESLANKTDPPTHLEPSFNIPASRGL---------ISSSSTLSTDTNDEELTSNN 1790
Query: 494 PAYKDLHKLALAREKQLKEKAE---KARGEKFGDNSNLNTTKAEE--ERSTSLDSELTQV 548
PA KD + E+ ++K E RGE + + N +E E D +
Sbjct: 1791 PAQKDSSNRNVQSEEDTEKKKEGEPVKRGEAIEEQTKSNKRPIDEVGELKNDEDDTTENI 1850
Query: 549 NE--KACVSDGLNKQSEDVKD 567
NE K D K+++ V D
Sbjct: 1851 NESKKIKTEDEEEKETDKVND 1871
Score = 57.8 bits (138), Expect = 1e-07
Identities = 69/287 (24%), Positives = 136/287 (47%), Gaps = 27/287 (9%)
Query: 12 DDEILSEF----ESLLSEQTDFPLLSEKTDDSKKHGGNETEMAKNGSDSEIEWLRNVVEE 67
++++L E E L + + LS TD++ + NE AK+ SD I + +++E
Sbjct: 340 NEDLLKELQLTKEKLAQCEKECLRLSSITDEADED--NENLSAKSSSDF-IFLKKQLIKE 396
Query: 68 LEEREMKLQSELLEYY-SLKEQVPVIEEFQRQLRIKSVEIDMLHMTIKSLQEENNKLQEE 126
+E LQ+++ + L+ +VP+I F+ + + E++ + ++ E N +E
Sbjct: 397 RRTKE-HLQNQIETFIVELEHKVPIINSFKERTDMLENELNNAALLLEHTSNEKNAKVKE 455
Query: 127 LIHEASAKRELEVARNKIKELQRQIKIIANQTKGQLLLLKQKVSG-----LQAKEEEVVK 181
L + ++L N ++ L +Q + Q Q LL+ VS L+ +E + ++
Sbjct: 456 L---NAKNQKLVECENDLQTLTKQRLDLCRQI--QYLLITNSVSNDSKGPLRKEEIQFIQ 510
Query: 182 KDAEIENNLKTVNDFEIEKKLKTVNDLEIE-AVGLKRRNKELQHEKRELTVKLNAAESRI 240
+ +++ T +D +K+ T +E + + L+ +N EL R L KL + E +
Sbjct: 511 NIMQEDDSTITESD---SQKVVTERLVEFKNIIQLQEKNAELLKVVRNLADKLESKEKKS 567
Query: 241 TELSSVTENEMIADAKSETGRLRHANEDLQKQVEGLQMNRFSEVEEL 287
+ E+E + +AK L+ DL+ ++E LQ E+EEL
Sbjct: 568 KQSLQKIESETVNEAKEAIITLKSEKMDLESRIEELQ----KELEEL 610
Score = 49.7 bits (117), Expect = 4e-05
Identities = 175/959 (18%), Positives = 372/959 (38%), Gaps = 180/959 (18%)
Query: 20 ESLLSEQTDFPLLSEKTDDSKKHGGNETEMAKNGSDSEIEWLRNVVEELEEREMK--LQS 77
+ L S+ + +KTD NE +N D ++E N V + + E+ LQ
Sbjct: 216 KELRSKNEQYLSYRQKTDKVILDIRNELNRLRN--DFQMERTNNDVLKQKNNELSKSLQE 273
Query: 78 ELLEYYSLKEQV-PVIEEFQRQLRIKSVEIDMLHMTIKSLQEENNKLQE----ELIHEAS 132
+LLE L + + +EF ++ +K +D+L + +++EE N ++E ++I + S
Sbjct: 274 KLLEIKGLSDSLNSEKQEFSAEMSLKQRLVDLLESQLNAVKEELNSIRELNTAKVIADDS 333
Query: 133 AK---------RELEVARNKIKELQRQI---------------KIIANQTKGQLLLLKQK 168
K +EL++ + K+ + +++ + A + + L KQ
Sbjct: 334 KKQTPENEDLLKELQLTKEKLAQCEKECLRLSSITDEADEDNENLSAKSSSDFIFLKKQL 393
Query: 169 VSGLQAKE---EEVVKKDAEIENNLKTVNDFEIEKKLKTVNDLEIEAVGLKRRNKELQHE 225
+ + KE ++ E+E+ + +N F+ E+ N+L A+ L+ + E +
Sbjct: 394 IKERRTKEHLQNQIETFIVELEHKVPIINSFK-ERTDMLENELNNAALLLEHTSNEKNAK 452
Query: 226 KRELTVKLNAAESRITELSSVTENE----------MIADAKSETGRLRHANEDLQ----- 270
+EL K +L ++T+ +I ++ S + E++Q
Sbjct: 453 VKELNAKNQKLVECENDLQTLTKQRLDLCRQIQYLLITNSVSNDSKGPLRKEEIQFIQNI 512
Query: 271 ----------KQVEGLQMNRFSEVEELVYLRWVNACLRYELRNY--KAPSGKSLARDLNN 318
+ + R E + ++ L+ NA L +RN K S + ++
Sbjct: 513 MQEDDSTITESDSQKVVTERLVEFKNIIQLQEKNAELLKVVRNLADKLESKEKKSKQSLQ 572
Query: 319 SFNPKSQEKAKQLMLEYAGSERGHGDTDIESNFSHDHSSPGSEDLDNAYINSPTYKYSNL 378
++ +AK+ ++ + D+ES + E+L + N YSN+
Sbjct: 573 KIESETVNEAKEAIITLKSEK-----MDLESRI--EELQKELEELKTSVPNEDA-SYSNV 624
Query: 379 SKKTSLIQKLKKWNKNNDSSAFSSPARSLSIGSPCRVSTSYRPRNTLESLMLRNAHDAVA 438
+ I++L + ++ +S R I R + E++ L N
Sbjct: 625 T-----IKQLTETKRDLESQVQDLQTRISQI-----------TRESTENMSLLN------ 662
Query: 439 ITTFEQKEHKPTHSPETPFLPSLRKVSSSDDILDSVSASFQLMSKSVDRSLDEKYPAYKD 498
KE + + ++ L K SS + + F+L+S ++D + E K
Sbjct: 663 ------KEIQDLYDSKSDISIKLGKEKSSRILAEE---RFKLLSNTLDLTKAENDQLRKR 713
Query: 499 LHKLALAREKQLKEKAEKARGEKFGDNSNLNTTKAEEERSTSLDSELTQVNEKACVSDGL 558
L KQ K + E S L+ E E + + +V+ + + L
Sbjct: 714 FDYLQNTILKQ-DSKTHETLNEYVSCKSKLSI--VETELLNLKEEQKLRVHLEKNLKQEL 770
Query: 559 NKQSEDVKDFDNQTITEMKLFKIEKRPPRLPRPPPKPSDGAPVSNSLNEIPYAPSVPSPP 618
NK S + KD +T+++ + E+ + ++L+E+ S
Sbjct: 771 NKLSPE-KDSLRIMVTQLQTLQKEREDLLEETRKSCQKKIDELEDALSELKKETSQK--- 826
Query: 619 PPPGSLPRGAVGDDKVKRAPE----LVEFYQSLMKREAKKDASLLTSSTSNAADTRSNVI 674
D +K+ E +E+YQ+ ++ K S++TS S D
Sbjct: 827 ------------DHHIKQLEEDNNSNIEWYQNKIEALKKDYESVITSVDSKQTD------ 868
Query: 675 AEIENRSSFLLAVKADVETQGDFVMSLATEVRAASFSKIEDVV---AFVNWLDEELSFLS 731
IE + +++ ++E ++R +++ +++ + + L++ L+
Sbjct: 869 --IEKLQYKVKSLEKEIEED---------KIRLHTYNVMDETINDDSLRKELEKSKINLT 917
Query: 732 DERAVLKHF-DWPEGKSDALREASFEYQDLMK-LEKQVSNFTDDPKLPCEDAL----QKM 785
D + +K + D E S +L++ + + + K Q+ N TD+ K ED + ++M
Sbjct: 918 DAYSQIKEYKDLYETTSQSLQQTNSKLDESFKDFTNQIKNLTDE-KTSLEDKISLLKEQM 976
Query: 786 YSLLEKLEQSVYALLRTR-DFAISRYKEFGVPVNWLLDSGVVGKIKLSSVQLANKYMKRI 844
++L +L+ + + + DF K ++S +Q NK ++ +
Sbjct: 977 FNLNNELDLQKKGMEKEKADF----------------------KKRISILQNNNKEVEAV 1014
Query: 845 ASEIDT-LSGPENEPTREFLILQGVRFSFRVHQFAGGFDTESMKAFEELRNNIHVQAGE 902
SE ++ LS +N+ ++ + + ++ + K ELR +H G+
Sbjct: 1015 KSEYESKLSKIQNDLDQQTIYANTAQNNYEQELQK---HADVSKTISELREQLHTYKGQ 1070
Score = 47.4 bits (111), Expect = 2e-04
Identities = 56/259 (21%), Positives = 116/259 (44%), Gaps = 37/259 (14%)
Query: 75 LQSELLEYYSLK-EQVPVIEEFQRQLRIKSVEIDMLHMTIKSLQEENNKLQEELI----- 128
L +LL++ LK E + V F +ID L ++++ EN+K+++E
Sbjct: 46 LNDKLLQFNELKSENLKVTVSFDELKASSLKKIDGLKTEMENVIRENDKIRKERNDTFVK 105
Query: 129 ------HEASAKRELEVARNKIKELQRQIKIIANQTKGQLLLLKQKVSGLQAKEEEVVKK 182
+ ELE + K+ +L + K + + L +L +++ ++ E +
Sbjct: 106 FESVENEKMKLSSELEFVKRKLDDLTEEKKETQSNQQRTLKILDERLKEIELVRVENNRS 165
Query: 183 DAEIENNLKTVNDFEIEKKLKTVNDLEIEAVGLKRRNKELQHEKRELTVKLNAAESRITE 242
++E + T+ D E +++ NDL EL+ + +ELT+ + + E
Sbjct: 166 NSECKKLRSTIMDLETKQQGYITNDL--------NSRTELERKTQELTLLQSNNDWLEKE 217
Query: 243 LSSVTE---------NEMIADAKSETGRLRH------ANEDLQKQVEGLQMNRFSEVEEL 287
L S E +++I D ++E RLR+ N D+ KQ + ++++ S E+L
Sbjct: 218 LRSKNEQYLSYRQKTDKVILDIRNELNRLRNDFQMERTNNDVLKQ-KNNELSK-SLQEKL 275
Query: 288 VYLRWVNACLRYELRNYKA 306
+ ++ ++ L E + + A
Sbjct: 276 LEIKGLSDSLNSEKQEFSA 294
Score = 43.1 bits (100), Expect = 0.003
Identities = 155/795 (19%), Positives = 317/795 (39%), Gaps = 142/795 (17%)
Query: 38 DSKKHGGNETEMAKNGSDSEIEWLRNVVEELEEREMKLQSELLEYYSLKEQVPVIEEFQR 97
DSK H ET S++ + + L+E E KL+ L + +LK+++ + +
Sbjct: 725 DSKTH---ETLNEYVSCKSKLSIVETELLNLKE-EQKLRVHLEK--NLKQELNKLSPEKD 778
Query: 98 QLRIKSVEI--------DMLHMTIKSLQEENNKLQEELIHEASAKRELEVARNKIKELQR 149
LRI ++ D+L T KS Q++ ++L++ L + K+E + IK+L+
Sbjct: 779 SLRIMVTQLQTLQKEREDLLEETRKSCQKKIDELEDAL---SELKKETSQKDHHIKQLEE 835
Query: 150 QIKIIANQTKGQLLLLKQK----VSGLQAKEEEVVKKDAEIENNLKTVNDFEIEKKLKTV 205
+ ++ LK+ ++ + +K+ ++ K ++++ K + + +I +L T
Sbjct: 836 DNNSNIEWYQNKIEALKKDYESVITSVDSKQTDIEKLQYKVKSLEKEIEEDKI--RLHTY 893
Query: 206 NDLEIEAVGLKRRNKELQHEKRELTVKLNAAESRITELSSVTENEMIADAKSETGRLRHA 265
N ++ E + KEL+ K + L A S+I E + E + +L +
Sbjct: 894 NVMD-ETINDDSLRKELEKSK----INLTDAYSQIKEYKDLYETTS-QSLQQTNSKLDES 947
Query: 266 NEDLQKQVEGLQMNRFSEVEELVYLRWVNACLRYEL-------RNYKAPSGKSLARDLNN 318
+D Q++ L + S +++ L+ L EL KA K ++ NN
Sbjct: 948 FKDFTNQIKNLTDEKTSLEDKISLLKEQMFNLNNELDLQKKGMEKEKADFKKRISILQNN 1007
Query: 319 SFN---PKSQEKAKQLMLE--------YAGSERGHGDTDIESNFSHDHSSPGSEDLDNAY 367
+ KS+ ++K ++ YA + + + + +++ + D S SE + +
Sbjct: 1008 NKEVEAVKSEYESKLSKIQNDLDQQTIYANTAQNNYEQELQKH--ADVSKTISELREQLH 1065
Query: 368 INSPTYKYSNLSKKTSLIQKLKKWNKNNDSSAFSSPARSLSIGSPCRVSTSYRPRNTLES 427
K NLS+ ++ K N+ + SS S L + + + +E
Sbjct: 1066 TYKGQVKTLNLSR--DQLENALKENEKSWSSQKESLLEQLDLSN-----------SRIED 1112
Query: 428 LMLRN--AHDAVAITTFEQKE-HKPTHSPE-TPFLPSLRKVSSSDDILDSVSASFQLMSK 483
L +N +D + I T KE + T+ P L +LR+ DILD+
Sbjct: 1113 LSSQNKLLYDQIQIYTAADKEVNNSTNGPGLNNILITLRR---ERDILDT---------- 1159
Query: 484 SVDRSLDEKYPAYKDLHKLALARE--KQLKEKAEKARGEKFGDNSNLNTTKAEEERSTSL 541
K+ +A K L++K E + L+ ++ E+E +S+
Sbjct: 1160 -----------------KVTVAERDAKMLRQKISLMDVELQDARTKLDNSRVEKENHSSI 1202
Query: 542 DSELTQVNEKACVSDGLNKQSEDVKDFDNQTITEMKLFKIEKRPPRLPRPPPKPSDGAPV 601
+ + EK + L + + +++ + K +++ +L + + AP+
Sbjct: 1203 IQQHDDIMEKLNQLNLLRESNITLRNELENNNNKKK--ELQSELDKLKQ------NVAPI 1254
Query: 602 SNSLNEIPYAPSVPSPPPPPGSLPRGAVGDDKVKRAPELVEFYQSLMKREAKKDASLLTS 661
+ L + Y+ + ++K A E V ++ + +K L +S
Sbjct: 1255 ESELTALKYSMQEK---------------EQELKLAKEEVHRWKKRSQDILEKHEQLSSS 1299
Query: 662 STSNAADTRSNVIAEIENRSSFLLAVKADVETQGDFVMSLATEVRAASFSKIEDVVAFVN 721
N+ E+EN+ E QG +R + +++ +
Sbjct: 1300 DYEKLESEIENLKEELENK-----------ERQGAEAEEKFNRLRRQAQERLKTSKLSQD 1348
Query: 722 WLDEELSFLSDERAVLKHFDWPEGKSDALREASFEYQDLMKLE-KQVSNFTDDPKLPCED 780
L E+++ L D + VL+ ++L EA+ ++L + Q +N + + ED
Sbjct: 1349 SLTEQVNSLRDAKNVLE---------NSLSEANARIEELQNAKVAQGNNQLEAIRKLQED 1399
Query: 781 ALQKMYSLLEKLEQS 795
A + L KLE+S
Sbjct: 1400 AEKASRELQAKLEES 1414
Score = 39.3 bits (90), Expect = 0.048
Identities = 60/326 (18%), Positives = 126/326 (38%), Gaps = 99/326 (30%)
Query: 16 LSEFESLLSEQTDFPLLSEKTDDSKKHGGNETEMAKNGSDSEIEWLRNVVEELE------ 69
+ E E LSE L ++T H + + ++S IEW +N +E L+
Sbjct: 809 IDELEDALSE------LKKETSQKDHH----IKQLEEDNNSNIEWYQNKIEALKKDYESV 858
Query: 70 ---------------------EREMKLQSELLEYYSLKEQVPVIEEFQRQLRIKSVEI-- 106
E+E++ L Y++ ++ + +++L + +
Sbjct: 859 ITSVDSKQTDIEKLQYKVKSLEKEIEEDKIRLHTYNVMDETINDDSLRKELEKSKINLTD 918
Query: 107 ---------DMLHMTIKSLQEENNKLQEELI-----------HEASAKRELEVARNKIKE 146
D+ T +SLQ+ N+KL E + S + ++ + + ++
Sbjct: 919 AYSQIKEYKDLYETTSQSLQQTNSKLDESFKDFTNQIKNLTDEKTSLEDKISLLKEQMFN 978
Query: 147 LQRQIKIIANQTKGQLLLLKQKVSGLQAKEEEVVKKDAEIENNLKTV------------- 193
L ++ + + + K+++S LQ +EV +E E+ L +
Sbjct: 979 LNNELDLQKKGMEKEKADFKKRISILQNNNKEVEAVKSEYESKLSKIQNDLDQQTIYANT 1038
Query: 194 --NDFEIEKKL-----KTVNDL---------EIEAVGLKR---------RNKELQHEKRE 228
N++E E + KT+++L +++ + L R K +K
Sbjct: 1039 AQNNYEQELQKHADVSKTISELREQLHTYKGQVKTLNLSRDQLENALKENEKSWSSQKES 1098
Query: 229 LTVKLNAAESRITELSSVTENEMIAD 254
L +L+ + SRI +LSS +N+++ D
Sbjct: 1099 LLEQLDLSNSRIEDLSS--QNKLLYD 1122
>NUF1_YEAST (P32380) NUF1 protein (Spindle poly body spacer protein
SPC110)
Length = 944
Score = 64.7 bits (156), Expect = 1e-09
Identities = 130/579 (22%), Positives = 232/579 (39%), Gaps = 129/579 (22%)
Query: 51 KNGSDSEIEWLRNVVEELEEREMKLQSELLEYYSLKEQVPVIEEFQR-----------QL 99
+N SD + LR+ +EL+ L +EL E S E+ EF++ +L
Sbjct: 254 ENNSDVQSLKLRSKEDELKN----LMNELNELKSNAEEKDTQLEFKKNELRKRTNELNEL 309
Query: 100 RIKSVEIDMLHMTIKSLQEENNKLQEELIH----------EASAKR-ELEVARNKIKELQ 148
+IKS E+D+ +K Q E+ +L++EL ++SAK EL++ +NKI EL+
Sbjct: 310 KIKSDEMDL---QLKQKQNESKRLKDELNELETKFSENGSQSSAKENELKMLKNKIAELE 366
Query: 149 RQI-----KIIANQTKGQLLL---------LKQKVSGLQAKEEE---------------- 178
+I ++IA + K L+ L Q+ S L ++EEE
Sbjct: 367 EEISTKNSQLIAKEGKLASLMAQLTQLESKLNQRDSQLGSREEELKKTNDKLQKDIRIAR 426
Query: 179 ------------VVKKDAEIENNL----------KTVNDFEIEKKLKTVNDLEIEAVGLK 216
+ KK ++EN+L KT+ D E+E K K + LE + +
Sbjct: 427 EETVSKDERIIDLQKKVKQLENDLFVIKKTHSESKTITDNELESKDKLIKILENDLKVAQ 486
Query: 217 RRNKELQHEKRELTVKLNAAESRITELSSVTENEMIADAKSETGRLRHANEDLQKQVEGL 276
+ +++ E +E +ES++ E T NE I++ +E +L++ ED +
Sbjct: 487 EKYSKMEKELKEREFNYKISESKL-EDEKTTLNEKISNLAAENSQLKNKIEDNSTATHHM 545
Query: 277 QMNRFSEVEELVYLRWVNACLRYELRNYKAPSGKSLARDLNNSFNPKSQEKAKQLMLEYA 336
+ N ++E LR ++ Y K A+D S++K ++L + A
Sbjct: 546 KENYEKQLES----------LRKDIEEY-----KESAKD--------SEDKIEELKIRIA 582
Query: 337 GSERGHGDTDIESNFSHDHSSPGSEDLDNAYINSPTYKYSNLSKKTSLIQKLKKWNKNND 396
+ S D + D + + +S S+I + KK + N
Sbjct: 583 -----ENSAKVSEKRSKDIKQKDEQISD--LTQNLKLQEDEISSLKSIIDRYKK-DFNQL 634
Query: 397 SSAFSSPARSLSIGSPCRVSTSYRPRNTLESLMLRNAHDAVAITTFEQKEHKPTHSPETP 456
S S+ L++ + + L+SL D+ I K S E
Sbjct: 635 KSEQSNIQHDLNLQILNLENKLIESEDELKSL-----RDSQKIEIENWKRKYNNLSLEND 689
Query: 457 FLPSLRKVSSSDDILDSVSASFQLMSKSVDRSLDEKYPAYKDLHKLALAREKQLKEKAEK 516
L + K S+SD ++++ +D EK+ + K +K + ++
Sbjct: 690 RLLT-EKESASDK-----EREISILNRKLDEMDKEKWNLQESKEKYKRELQKVITAN-DR 742
Query: 517 ARGEKFGDNSNLNTTKAEEERSTSLD----SELTQVNEK 551
R EK N N N + E++ T + SE+T + E+
Sbjct: 743 LRREKEELNENSNNIRIMEDKMTRIKKNYLSEITSLQEE 781
Score = 55.1 bits (131), Expect = 9e-07
Identities = 108/580 (18%), Positives = 232/580 (39%), Gaps = 87/580 (15%)
Query: 58 IEWLRNVVEELEEREMKLQSELLEYYSLKEQVPVIEEFQRQLRIKSVEIDMLHMTIKSLQ 117
I ++++ E++E + L Y +L+E+ ++ + +L+ E+D + + S +
Sbjct: 162 INEIKSLKHEIKELRKEKNDTLNNYDTLEEET---DDLKNRLQALEKELDAKNKIVNSRK 218
Query: 118 EENNKLQEELIHEASAKRELEVARNKIKELQRQIKIIANQTKGQLLLLKQKVSGLQAKEE 177
+++ E +R+L K+K ++ Q+ + N + Q L L+ K L+
Sbjct: 219 VDDHSGCIE--EREQMERKLAELERKLKTVKDQVLELENNSDVQSLKLRSKEDELKNLMN 276
Query: 178 EV--VKKDAEIENNLKTVNDFEIEKKLKTVNDLEIEAVGLKRRNKELQHEKRELTVKLNA 235
E+ +K +AE ++ E+ K+ +N+L+I++ + + K+ Q+E + L +LN
Sbjct: 277 ELNELKSNAEEKDTQLEFKKNELRKRTNELNELKIKSDEMDLQLKQKQNESKRLKDELNE 336
Query: 236 AESRITE---LSSVTENEM------IADAKSETG-------------------------- 260
E++ +E SS ENE+ IA+ + E
Sbjct: 337 LETKFSENGSQSSAKENELKMLKNKIAELEEEISTKNSQLIAKEGKLASLMAQLTQLESK 396
Query: 261 -------------RLRHANEDLQKQVEGLQMNRFSEVEELVYLRWVNACLRYELRNYKAP 307
L+ N+ LQK + + S+ E ++ L+ L +L K
Sbjct: 397 LNQRDSQLGSREEELKKTNDKLQKDIRIAREETVSKDERIIDLQKKVKQLENDLFVIKKT 456
Query: 308 SGKSLARDLNNSFNPKSQEKAKQLMLEYAGSERGHGDTDI-ESNFSHDHSSPGSEDLDNA 366
+S N + K + L+ A + + ++ E F++ S ED +
Sbjct: 457 HSESKTITDNELESKDKLIKILENDLKVAQEKYSKMEKELKEREFNYKISESKLED-EKT 515
Query: 367 YINSPTYKYSNLSKKTSLIQKLKKWNKNNDSSA--------FSSPARSLSIGSPCRVSTS 418
+N K SNL+ + S ++ NK D+S + SL ++
Sbjct: 516 TLNE---KISNLAAENSQLK-----NKIEDNSTATHHMKENYEKQLESLRKDIEEYKESA 567
Query: 419 YRPRNTLESLMLRNAHDAVAITTFEQKEHKPTHSPETPFLPSLR----KVSSSDDILDSV 474
+ +E L +R A ++ ++ K+ K + +L+ ++SS I+D
Sbjct: 568 KDSEDKIEELKIRIAENSAKVSEKRSKDIKQKDEQISDLTQNLKLQEDEISSLKSIIDRY 627
Query: 475 SASFQLMSKSVDRSLDEKYPAYKDLHKLALAREKQLK-----EKAEKARGEKFGDNSNLN 529
F + + +L + E +LK +K E ++ +N +L
Sbjct: 628 KKDFNQLKSEQSNIQHDLNLQILNLENKLIESEDELKSLRDSQKIEIENWKRKYNNLSLE 687
Query: 530 TTK--AEEERSTSLDSELTQVNEKACVSDGLNKQSEDVKD 567
+ E+E ++ + E++ +N K D ++K+ ++++
Sbjct: 688 NDRLLTEKESASDKEREISILNRKL---DEMDKEKWNLQE 724
Score = 42.4 bits (98), Expect = 0.006
Identities = 56/272 (20%), Positives = 125/272 (45%), Gaps = 26/272 (9%)
Query: 8 ANDFDDEILSEFESLLSEQTDFPLLSEKTDDSKKHGGNETEMAKNGS--DSEIEWLRNVV 65
A D +D+I E + ++E + + +++ D K+ +++ +N + EI L++++
Sbjct: 567 AKDSEDKI-EELKIRIAENSA-KVSEKRSKDIKQKDEQISDLTQNLKLQEDEISSLKSII 624
Query: 66 E-------ELEEREMKLQSEL-LEYYSLKEQVPVIEEFQRQLR-IKSVEIDMLHMTIKSL 116
+ +L+ + +Q +L L+ +L+ ++ E+ + LR + +EI+ +L
Sbjct: 625 DRYKKDFNQLKSEQSNIQHDLNLQILNLENKLIESEDELKSLRDSQKIEIENWKRKYNNL 684
Query: 117 QEENNKLQEELIHEASAKRELEVARNKIKELQRQIKIIANQTKGQLLLLKQKVSGLQAKE 176
EN++L E + +RE+ + K+ E+ ++ K ++K + QKV +
Sbjct: 685 SLENDRLLTEKESASDKEREISILNRKLDEMDKE-KWNLQESKEKYKRELQKVITANDRL 743
Query: 177 EEVVKKDAEIENNLKTVNDFEIEKKLKTVNDLEIEAVGLKRRNKELQHEKRELTVKLNAA 236
++ E NN++ + D K ++++ LQ E R L +L
Sbjct: 744 RREKEELNENSNNIRIMEDKMTRIKKNYLSEI-----------TSLQEENRRLEERLILN 792
Query: 237 ESRITELSSVTENEMIADAKSE-TGRLRHANE 267
E R S++ N++I+ K + +RH N+
Sbjct: 793 ERRKDNDSTMQLNDIISYYKLKYHSEVRHNND 824
>RA50_ARCFU (O29230) DNA double-strand break repair rad50 ATPase
Length = 886
Score = 64.3 bits (155), Expect = 1e-09
Identities = 70/298 (23%), Positives = 137/298 (45%), Gaps = 34/298 (11%)
Query: 55 DSEIEW--LRNVVEELEEREMKLQSELLEYYSLKEQVPVIEEFQRQLRIKSVEIDMLHMT 112
D E W L V+ LE + +L+ E+ S +EQ+ +RQ K EI+ +
Sbjct: 153 DYENAWKNLGAVIRMLEREKERLK----EFLSQEEQI------KRQKEEKKAEIERISEE 202
Query: 113 IKSLQEENNKLQEELIHEASAKRELEVARNKIKELQRQIKIIANQTKGQLLLLKQKVSGL 172
IKS++ KL EE+ + S +ELE +++++ L++Q + + +G L++K+ L
Sbjct: 203 IKSIESLREKLSEEVRNLESRLKELEEHKSRLESLRKQESSVLQEVRG----LEEKLREL 258
Query: 173 QAKEEEVVKKDAEIENNLKTVNDFE--------IEKKLKTVNDLEIEAVGLKRRNKELQH 224
+ + +EVV++ ++E K V + + +EK L +N + +++R +L
Sbjct: 259 EKQLKEVVERIEDLEKKAKEVKELKPKAERYSILEKLLSEINQALRD---VEKREGDLTR 315
Query: 225 EKRELTVKLNAAESRITELSSVTENEMIADAKSETGRLRHAN---EDLQKQVEGLQMNRF 281
E + +L AE ++L +T+ I + + E R ++ E L+ +++ +Q +
Sbjct: 316 EAAGIQAQLKKAEEDNSKLEEITKR--IEELERELERFEKSHRLLETLKPKMDRMQGIKA 373
Query: 282 SEVEELVYLRWVNACLRYELRNYKAPSGKSLARDLNNSFNPKSQEKAKQLMLEYAGSE 339
E+ + V Y+L + K + L KS K + L+ A E
Sbjct: 374 KLEEKNLTPDKVEK--MYDLLSKAKEEEKEITEKLKKLIAKKSSLKTRGAQLKKAVEE 429
Score = 45.8 bits (107), Expect = 5e-04
Identities = 45/229 (19%), Positives = 108/229 (46%), Gaps = 13/229 (5%)
Query: 51 KNGSDSEIEWLRNVVEELEEREMKLQSELLEYYSLKEQVPVIEEFQRQLRIKSVEIDMLH 110
K +EIE + ++ +E KL E+ +L+ ++ +EE + +L + +
Sbjct: 189 KEEKKAEIERISEEIKSIESLREKLSEEVR---NLESRLKELEEHKSRLESLRKQESSVL 245
Query: 111 MTIKSLQEENNKLQEELIHEASAKRELEVARNKIKELQRQIKIIANQTKGQLLLLKQKVS 170
++ L+E+ +L+++L +LE ++KEL+ + + + K L + Q +
Sbjct: 246 QEVRGLEEKLRELEKQLKEVVERIEDLEKKAKEVKELKPKAERYSILEK-LLSEINQALR 304
Query: 171 GLQAKEEEVVKKDAEIENNLKTV--NDFEIEKKLKTVNDLEIEAVGLKRRNKELQHEKRE 228
++ +E ++ ++ A I+ LK ++ ++E+ K + +LE E ++ ++ L+ K +
Sbjct: 305 DVEKREGDLTREAAGIQAQLKKAEEDNSKLEEITKRIEELERELERFEKSHRLLETLKPK 364
Query: 229 LT----VKLNAAESRITELSSVTENEMIADAKSETGRLRHANEDLQKQV 273
+ +K E +T ++++ AK E + E L+K +
Sbjct: 365 MDRMQGIKAKLEEKNLTPDKVEKMYDLLSKAKEEE---KEITEKLKKLI 410
Score = 42.4 bits (98), Expect = 0.006
Identities = 56/263 (21%), Positives = 116/263 (43%), Gaps = 14/263 (5%)
Query: 14 EILSEFESLLSEQTDFPLLSEKTDDSKKHGGNETEMAKNGSDSEIEWLRNVVEELEEREM 73
E LS+ E + ++ + E+ + K E + E+ L + ++ELEE +
Sbjct: 177 EFLSQEEQIKRQKEEKKAEIERISEEIK----SIESLREKLSEEVRNLESRLKELEEHKS 232
Query: 74 KLQSELLEYYSLKEQVPVIEEFQRQLRIKSVEIDMLHMTIKSLQEENNKLQEELIHEASA 133
+L+S + S+ ++V +EE R+L + E+ ++ +E +L+ + +
Sbjct: 233 RLESLRKQESSVLQEVRGLEEKLRELEKQLKEVVERIEDLEKKAKEVKELKPKAERYSIL 292
Query: 134 KRELEVARNKIKELQRQIKIIANQTKGQLLLLKQKVSGLQAKEEEVVKKDAEIENNLKTV 193
++ L +++++++ + + G LK K +K EE+ K+ E+E L+
Sbjct: 293 EKLLSEINQALRDVEKREGDLTREAAGIQAQLK-KAEEDNSKLEEITKRIEELERELERF 351
Query: 194 -NDFEIEKKLKTVNDLEIEAVGLKRRNKELQHEKRE----LTVKLNAAESRITE-LSSVT 247
+ + LK D ++ + K K L +K E L K E ITE L +
Sbjct: 352 EKSHRLLETLKPKMD-RMQGIKAKLEEKNLTPDKVEKMYDLLSKAKEEEKEITEKLKKLI 410
Query: 248 ENEMIADAKSETGRLRHANEDLQ 270
+ + K+ +L+ A E+L+
Sbjct: 411 AKK--SSLKTRGAQLKKAVEELK 431
>RA50_METMP (P62134) DNA double-strand break repair rad50 ATPase
Length = 993
Score = 63.2 bits (152), Expect = 3e-09
Identities = 91/406 (22%), Positives = 172/406 (41%), Gaps = 59/406 (14%)
Query: 13 DEILSEFESLLSEQTDFPLLSEKTDDSKKHGGNE-TEMAKNGSDSEIEWLRNVVEELEER 71
+EI+ + ES +SE + EKT DS ++ TE K E LE+
Sbjct: 470 NEIVLKKESKISEYKNSKAELEKTKDSCHVCQSKITEEKKQ-------------ELLEKY 516
Query: 72 EMKLQSELLEYYSLKEQVPVIEEFQRQLRIKSVEIDMLHMTIKSLQEENN---KLQEELI 128
++Q+E L SLK+Q+ +I + ++++K EID + L+E+ N K++E +I
Sbjct: 517 NSEIQNEQLSTESLKKQLEIILNKKEKMKVKLNEIDSFKLKYGELKEKKNYSLKVEESII 576
Query: 129 HEASAKRELEVARNKIKELQRQIKIIANQTK-----------GQLLLLKQKVSGLQAKEE 177
EL N+ L +I +I N+ K L K S K+
Sbjct: 577 ETTEKLNELTGKINEYSSLNDEISLIENKLKNLENDYKNCNYSSQFLTKNDESEFLTKKL 636
Query: 178 EVVK-----KDAEIENNLKTVNDFEIEKKLKTVNDLEIEAVGLKRRNKELQHEKRELTVK 232
E+ K ++IEN K++ + + E K T+ +LE E + LK KEL++ + +++ K
Sbjct: 637 ELSKIIGDYDSSKIENEKKSLENLKDELK-NTIYNLERE-INLK---KELKNIQNDISSK 691
Query: 233 LNAAESRITELSSVTENEMIADAKSETGRLRHANEDLQKQVEGLQMNRFSEVEELVYLRW 292
+ E + + ++ E +L E+ +K +E L + + V +
Sbjct: 692 IGIVECYVKWETEKSDFE---------NKLSECKENYEKYMESLAVLKNYSKTYSVEINN 742
Query: 293 VNACLRYELRNYKAPSGK------SLARDLNN-SFNPKSQEKAKQLMLEYAGSERGHGDT 345
+N L ++ + K + +++ ++NP+ E AK+L
Sbjct: 743 LNEFLNQKIAEKQQFCEKLLETRTEIEKNIQTVNYNPELHENAKRLYENILNE-----FN 797
Query: 346 DIESNFSHDHSSPGSEDLDNAYINSPTYKYSNLSKKTSLIQKLKKW 391
DI S ++ + +Y+N SN ++ I++ K++
Sbjct: 798 DILRTLERISSELKLKNENISYLNEKIQNLSNKKEEKKKIEEFKEY 843
Score = 53.1 bits (126), Expect = 3e-06
Identities = 93/428 (21%), Positives = 187/428 (42%), Gaps = 55/428 (12%)
Query: 13 DEILSEFESL----LSEQTDFPLLSEKTDDSKKHGGN-------------ETEMAKNGSD 55
+EIL ++E+L L + ++ + EK ++ + N E + KN +
Sbjct: 210 EEILKKYENLEKLKLEKNSEILQMEEKFAENNQLKENLKDIISEIKNINLEIQNFKNSLN 269
Query: 56 SEIEWLRNVVEELEEREMKLQSELLEYYSLKEQVPVIEEFQRQLRIKSVEIDMLHM--TI 113
E +N+ E E + L+ EL + + ++ ++K++E +L +
Sbjct: 270 LVAEESKNISENEENYKKYLELELKIKELNNKLIGHKSNYESYNKLKTIEESLLKELGVL 329
Query: 114 KSLQEENNKLQEELIHEASAKRELEVARNKIKELQRQIKIIANQTKGQLLLLKQKVSGLQ 173
K ++N K +EL E + +KIKE ++++ I Q ++ + K+ V L
Sbjct: 330 KESLKDNKKNPDELKENLKENDEKILILDKIKEKIKELEFIEKQIY-EIKIHKKTVETLF 388
Query: 174 AKE----------EEVVKKDAEIENNLKTVNDFEIEKKLKTVNDLEIEAVGLKRRNKELQ 223
EE+ K EN LK F++EKKL+ D + + + ++
Sbjct: 389 DSVKIYDDSIKTFEELKTKKNSYENLLK--EKFDLEKKLQNETDEKTKLI-----SELTD 441
Query: 224 HEKRELTVKL-NAAESRITELSSVTE--NEMIADAKSETGRLRHANEDLQKQVEGLQM-- 278
EK E + L N + + +LS + NE++ +S+ +++ +L+K + +
Sbjct: 442 FEKIEEKINLENELKEKYEDLSEKIDKLNEIVLKKESKISEYKNSKAELEKTKDSCHVCQ 501
Query: 279 NRFSEVEELVYLRWVNACLRYELRNYKAPSGKSLARDLNNSFNPKSQEKAKQLMLEYAGS 338
++ +E ++ L N+ E++N + S +SL + L N K EK K + E
Sbjct: 502 SKITEEKKQELLEKYNS----EIQNEQL-STESLKKQLEIILNKK--EKMKVKLNEIDSF 554
Query: 339 ERGHGDTDIESNFS---HDHSSPGSEDLDNAYINSPTYKYSNLSKKTSLIQ-KLKKWNKN 394
+ +G+ + N+S + +E L+ + +YS+L+ + SLI+ KLK +
Sbjct: 555 KLKYGELKEKKNYSLKVEESIIETTEKLNE--LTGKINEYSSLNDEISLIENKLKNLEND 612
Query: 395 NDSSAFSS 402
+ +SS
Sbjct: 613 YKNCNYSS 620
>MYS3_HYDAT (P39922) Myosin heavy chain, clone 203 (Fragment)
Length = 539
Score = 63.2 bits (152), Expect = 3e-09
Identities = 66/266 (24%), Positives = 122/266 (45%), Gaps = 14/266 (5%)
Query: 13 DEILSEFESLLSEQTDFPLLSEKTDDS-KKHGGNETEMAKNGSDSEIEWLRNVVEELEER 71
D +++ + LL+ QT L +++ +K G E + + +I+ ++EL E+
Sbjct: 99 DRLITIEDKLLNLQTVKDKLESSLNEALEKLDGEEHSVLV--LEEKIQEAEEKIDELTEK 156
Query: 72 EMKLQSELLEYYSLKE-QVPVIEEFQRQLRIKSVEIDMLHMTIKSLQEENNKLQEELIHE 130
+LQS + + K+ + I+ +R + I ++ K + EE E+L
Sbjct: 157 TEELQSNISRLETEKQNRDKQIDTLNEDIRKQDETISKMNAEKKHVDEELKDRTEQLQAA 216
Query: 131 ASAKRELEVARNKIKELQRQIKIIANQTKGQLLLLKQKVSGLQAKEEEVVKKDAEIENNL 190
L +NK++ R+I+ + K + L+++ +++ ++ K +E E L
Sbjct: 217 EDKCNNLNKTKNKLESSIREIEQDLKKEKDSKMKLEKEKKKVESDLKDNRDKLSETETRL 276
Query: 191 KTVNDFEIEKKLKTVNDLEIEAVGLKRRNKELQHEKRELTVKLNAAESRITELSSVTENE 250
K D + K+ K+++DLE GL+ + +LQ + +EL K I EL ENE
Sbjct: 277 KETQDL-VTKREKSISDLENAKEGLESQISQLQRKIQELLAK-------IEELEEELENE 328
Query: 251 MIADAKSETGR--LRHANEDLQKQVE 274
KSE R L E+LQ Q+E
Sbjct: 329 RKLRQKSELQRKELESRIEELQDQLE 354
Score = 51.2 bits (121), Expect = 1e-05
Identities = 56/268 (20%), Positives = 124/268 (45%), Gaps = 23/268 (8%)
Query: 13 DEILSEFESLLSEQTDFPLLSEKTDDSKKHGGNETEMAKNGSDSEIEWLRNVVEELEERE 72
+E + E E + E L+EKT++ + + + E K D +I+ L + + +E
Sbjct: 140 EEKIQEAEEKIDE------LTEKTEELQSNI-SRLETEKQNRDKQIDTLNEDIRKQDETI 192
Query: 73 MKLQSELLEYYSLKEQVPVIEEFQRQLRIKSVEIDMLHMTIKSLQEENNKLQEELIHEAS 132
K+ +E K +++ QL+ + + L+ T L+ +++++L E
Sbjct: 193 SKMNAEK------KHVDEELKDRTEQLQAAEDKCNNLNKTKNKLESSIREIEQDLKKEKD 246
Query: 133 AKRELEVARNKIKELQRQIKIIANQTKGQLLLLKQKVSGLQAKEEEVVKKDAEIENNLKT 192
+K +LE + K++ + + ++T+ +L + V+ + ++ +E+ +
Sbjct: 247 SKMKLEKEKKKVESDLKDNRDKLSETETRLKETQDLVTKREKSISDLENAKEGLESQISQ 306
Query: 193 VNDFEIEKKLKTVNDLEIEAVGLKRRNKELQHEKRELTVKLNAAESRITELSSVTENEMI 252
+ +I++ L + +LE E ++ ++ + +++EL ESRI EL E
Sbjct: 307 LQR-KIQELLAKIEELEEELENERKLRQKSELQRKEL-------ESRIEELQDQLETAGG 358
Query: 253 A-DAKSETGRLRHAN-EDLQKQVEGLQM 278
A A+ E G+ R A L+K++E L +
Sbjct: 359 ATSAQVEVGKKREAECNRLRKEIEALNI 386
Score = 47.8 bits (112), Expect = 1e-04
Identities = 66/286 (23%), Positives = 127/286 (44%), Gaps = 57/286 (19%)
Query: 46 ETEMAKNGSDSEIEWLRNVVEELEEREMKLQSELLEYYSLKEQVPVIEEFQRQLRIKSVE 105
E EM + E+E + +++ E + K++ EL E + KE++ + + R+ ++E
Sbjct: 49 EDEM--RAKEEELEAAKEQLKKDAEAKKKMEEELTEAMAQKEKLYASLQAETD-RLITIE 105
Query: 106 IDMLHM-TIK-----SLQEENNKLQ---------EELIHEASAKRELEVARNKIKELQRQ 150
+L++ T+K SL E KL EE I EA K ++ K +ELQ
Sbjct: 106 DKLLNLQTVKDKLESSLNEALEKLDGEEHSVLVLEEKIQEAEEK--IDELTEKTEELQSN 163
Query: 151 IKIIANQTKGQLLLLKQKVSGLQAKEEEVVKKDAEIE--------------------NNL 190
I + + + + + ++ ++E + K +AE + NNL
Sbjct: 164 ISRLETEKQNRDKQIDTLNEDIRKQDETISKMNAEKKHVDEELKDRTEQLQAAEDKCNNL 223
Query: 191 -KTVNDF-----EIEKKLKTVNDLEIEAVGLKRRNKELQHEKRELTVKLNAAESRITELS 244
KT N EIE+ LK D +++ L++ K+++ + ++ KL+ E+R+ E
Sbjct: 224 NKTKNKLESSIREIEQDLKKEKDSKMK---LEKEKKKVESDLKDNRDKLSETETRLKE-- 278
Query: 245 SVTENEMIADAKSETGRLRHANEDLQKQVEGLQ---MNRFSEVEEL 287
+++ + L +A E L+ Q+ LQ +++EEL
Sbjct: 279 ---TQDLVTKREKSISDLENAKEGLESQISQLQRKIQELLAKIEEL 321
Score = 44.3 bits (103), Expect = 0.002
Identities = 59/279 (21%), Positives = 110/279 (39%), Gaps = 66/279 (23%)
Query: 16 LSEFESLLSEQTDFPLLSEKTDDSKKHGGNETEMAKNGSDSEIEWLRNVVEELEEREMKL 75
LSE E+ L E D EK+ ++ E AK G +S+I L+ ++EL + +L
Sbjct: 269 LSETETRLKETQDLVTKREKSI-------SDLENAKEGLESQISQLQRKIQELLAKIEEL 321
Query: 76 QSELLEYYSLKEQVPV--------IEEFQRQLRIKS---------------------VEI 106
+ EL L+++ + IEE Q QL EI
Sbjct: 322 EEELENERKLRQKSELQRKELESRIEELQDQLETAGGATSAQVEVGKKREAECNRLRKEI 381
Query: 107 DMLHM---------------TIKSLQEENNKLQEELIHEASAKRELEVARNKIKELQRQI 151
+ L++ TI +QEEN +++ +A ++E N++
Sbjct: 382 EALNIANDAAISAIKAKTNATIAEIQEENEAMKKA---KAKLEKEKSALNNEL------- 431
Query: 152 KIIANQTKGQLLLLKQKVSGLQAKEEEVVKKDAEIENNLKTVNDFEIEKKLKTVNDLEIE 211
N+TK L +K++ + + ++ E+ + L V++ + + K + + E
Sbjct: 432 ----NETKNSLDQIKKQKTNSDKNSRMLEEQINELNSKLAQVDELHSQSESKN-SKVNSE 486
Query: 212 AVGLKRRNKELQHEKRELTVKLNAAESRITELSSVTENE 250
+ L + E +H T + ES++ E + E E
Sbjct: 487 LLALNSQLSESEHNLGIATKNIKTLESQLAESKNFNEAE 525
>SMC2_XENLA (P50533) Structural maintenance of chromosome 2
(Chromosome-associated protein E) (Chromosome assembly
protein XCAP-E)
Length = 1203
Score = 62.8 bits (151), Expect = 4e-09
Identities = 63/241 (26%), Positives = 112/241 (46%), Gaps = 21/241 (8%)
Query: 58 IEWLRNVVEELEEREMKLQSELLEYYSLKEQVPVIEEFQRQLRIKSVEIDMLHMTIKSLQ 117
++ L++V +EL+ +E +LQ E +LK V + ++Q +KS E ++L ++ Q
Sbjct: 679 LQELKDVQDELKAKETELQEVEKELMTLKNTVERYRQLKQQWEMKSEEAELLQTKLQ--Q 736
Query: 118 EENNKLQEELIH--------EASAKRELEV---ARNKIKELQRQIKIIANQTKGQLLLLK 166
+K QEEL E + K EV A K K L+ ++K + + +L +
Sbjct: 737 SSYHKQQEELDSLKQTIEESEETLKNTKEVQKKAEEKFKVLEHKMKNAEAERERELKEAQ 796
Query: 167 QKVSGLQAKEEEVVKKDAEIENNLKT-VNDFEIEKKLKTVNDLEIEAV--GLKRRNKELQ 223
QK+ + K + KK E + + V + E K+ +T +IE V +K ++
Sbjct: 797 QKLDTAKKKADASNKKMKEKQQEVDALVLELEELKREQTTYKQQIETVDEAMKAYQEQAD 856
Query: 224 HEKRELTVKLNAAESRITELSSVTE-----NEMIADAKSETGRLRHANEDLQKQVEGLQM 278
E++ A + EL+ E ++ I SE G+LR N DLQ +++ L+
Sbjct: 857 SMASEVSKNKEAVKKAQDELAKQKEIIMGHDKEIKTKSSEAGKLRENNNDLQLKIKELEH 916
Query: 279 N 279
N
Sbjct: 917 N 917
Score = 35.0 bits (79), Expect = 0.91
Identities = 53/236 (22%), Positives = 92/236 (38%), Gaps = 24/236 (10%)
Query: 13 DEILSEFESLLSEQTDFPLLSEKTDDSKKHGGNETEMAKNGSDSEIEWLRNVVEELEERE 72
+E+ +S+L Q K + K +M + L + E + +
Sbjct: 251 EELKEMQDSILKLQDTMAENERKVKELGKEIAELEKMRDQEVGGALRSLEEALSEAQRAD 310
Query: 73 MKLQSEL-LEYYSLK--------EQVPVIEEFQRQLRIKSVEIDMLHMTIKSLQEENNKL 123
K+QS L L+ ++K E V +EE + L K E+ + + SLQE + K
Sbjct: 311 TKVQSALDLKKQNMKAEREKKRKELVKSMEEDAKVLTAKEKEVKKITDGLSSLQEASQKD 370
Query: 124 QEELIHEASAKRELEVARNKIKE--------LQRQIKIIANQTKGQLLLLKQKVSGLQAK 175
E SA++ + L Q+ N+T KQ L+
Sbjct: 371 VEAF---TSAQQHFNAVSAGLSSNEDGEEATLAGQMMACKNETSKAETEAKQAQMKLKHA 427
Query: 176 EEEVVKKDAEI---ENNLKTVND-FEIEKKLKTVNDLEIEAVGLKRRNKELQHEKR 227
++E+ K AE+ + K N+ FE KK K ++E++ + + +E EKR
Sbjct: 428 QQELKTKQAEVKKMDGGYKKDNEAFEAVKKSKEKLEVEMKKLNYEDGREEQLLEKR 483
>REST_CHICK (O42184) Restin (Cytoplasmic linker protein-170)
(CLIP-170)
Length = 1433
Score = 62.0 bits (149), Expect = 7e-09
Identities = 68/279 (24%), Positives = 127/279 (45%), Gaps = 43/279 (15%)
Query: 16 LSEFESLLSEQTDFPLLSEKTDDSKKHGGNETEMAKNGSDSEIEWLRNVVEELEEREMKL 75
L+ E+ L E+ + + T+ K + E+ K+ DS + L + +EL +E +L
Sbjct: 886 LTVMETKLKEREERE--QQLTEAKVKLENDIAEIMKSSGDSSAQ-LMKMNDELRLKERQL 942
Query: 76 QSELLEYYSLKEQVPVIEEFQRQLRIKSVEIDMLHMTIKSLQEENNKLQEELIHEASAKR 135
+ LE E+ +++ Q K+ + T+K+ QEE K+Q++L K+
Sbjct: 943 EQIQLELTKANEKAVQLQKNVEQTAQKAEQSQQ--ETLKTHQEELKKMQDQL---TDMKK 997
Query: 136 ELEVARNKIKELQRQIKIIANQTKGQLLLLKQKVSGLQAKEEEVVKKDAEIENNLKTVND 195
++E ++N+ K+LQ + + + E + K DA+I+ + + D
Sbjct: 998 QMETSQNQYKDLQAKYE--------------------KETSEMITKHDADIKGFKQNLLD 1037
Query: 196 FE--IEKKLKTVNDLEIEAVGLKRRNKELQHEKRELTVKLNAAESRITELSSVT-ENEMI 252
E ++ K ++LE +A LK++ ++ + +KR AE + + VT E + I
Sbjct: 1038 AEEALKAAQKKNDELETQAEELKKQAEQAKADKR--------AEEVLQTMEKVTKEKDAI 1089
Query: 253 ADAKSET----GRLRHANEDLQKQVEGLQMNRFSEVEEL 287
K ET R NE LQ +++ L+ N EEL
Sbjct: 1090 HQEKIETLASLENSRQTNEKLQNELDMLKQNNLKNEEEL 1128
Score = 53.9 bits (128), Expect = 2e-06
Identities = 153/768 (19%), Positives = 300/768 (38%), Gaps = 86/768 (11%)
Query: 32 LSEKTDDSKKHGGNETEMAKNGSDSEIEWLRNVVEELEEREMK-LQSELLEYYSLKEQVP 90
L K D + K + E+ K+ +S I + +EEL+ K + ++ E+ LK Q+
Sbjct: 595 LKTKLDHANKENSDVIELWKSKLESAIASHQQAMEELKVSFNKGVGAQTAEFAELKTQM- 653
Query: 91 VIEEFQRQLRIKSVEIDMLH-MTIKSLQEENNKLQEELIHEASAKRELEVARNKIKELQR 149
+ V++D + M+ L++EN K Q EA + LEV K + L+
Sbjct: 654 -----------EKVKLDYENEMSNLKLKQENEKSQHLKEIEALKAKLLEVTEEKEQTLEN 702
Query: 150 QIKIIANQTKGQLLLLKQKVSGLQAKEEEVVKKDA-EIENNLKTVNDFEIEKKLKTVNDL 208
+ + L+ ++ ++ LQ E +V + D + + N +T + ++++ +
Sbjct: 703 LKAKLESVEDQHLVEMEDTLNKLQEAEIKVKELDVLQAKCNEQTKLIGSLTQQIRASEEK 762
Query: 209 EIEAVGLKRRNKELQHEKRELTVKLNAAESRITELSSVTENEMIADAKSETGRLRHANED 268
++ L++ N E + E ++L+ +L AAE +I L E E +++ E D
Sbjct: 763 LLDLAALQKANSEGKLEIQKLSEQLQAAEKQIQNL----ETEKVSNLTKELQGKEQKLLD 818
Query: 269 LQKQVEGLQMNRFSEVEELVYLRWVNACLRYELRNYKAPSGKSLARDLNNSFNPKSQEKA 328
L+K + + + S +EL L+ E ++ R + + N K +K
Sbjct: 819 LEKNLSAVNQVKDSLEKELQLLK--------EKFTSAVDGAENAQRAMQETIN-KLNQKE 869
Query: 329 KQLMLEYAGSERGHGDTDIESNFSHDHSSPGSEDLDNAYINSPTYKYSNLSKKTSLIQKL 388
+Q L + E+ ++SN + + + + K N + + +
Sbjct: 870 EQFALMSSELEQ------LKSNLTVMETKLKEREEREQQLTEAKVKLEN-----DIAEIM 918
Query: 389 KKWNKNNDSSAFSSPARSLSIGSPCRVSTSYRPRNTLESLMLRNAHDAVAITTFEQKEHK 448
K S+ S A+ + + R+ + LE L N EQ K
Sbjct: 919 K--------SSGDSSAQLMKMNDELRLKERQLEQIQLE-LTKANEKAVQLQKNVEQTAQK 969
Query: 449 PTHSPETPFLPSLRKVSSSDDILDSVSASFQLMSKSVDRSLDEKYPAYKDLHKLALAREK 508
S + ++ D L M K ++ S ++ YKDL EK
Sbjct: 970 AEQSQQETLKTHQEELKKMQDQLTD-------MKKQMETSQNQ----YKDLQ---AKYEK 1015
Query: 509 QLKEKAEKARGEKFGDNSNL----NTTKAEEERSTSLDSELTQVNEKACVSDGLNKQSED 564
+ E K + G NL KA ++++ L+++ ++ ++A + +K++E+
Sbjct: 1016 ETSEMITKHDADIKGFKQNLLDAEEALKAAQKKNDELETQAEELKKQAEQAKA-DKRAEE 1074
Query: 565 VKDFDNQTITEMKLFKIEKRPPRLPRPPPKPSDGAPVSNSLNEIPYAPSVPSPPPPPGSL 624
V + +T+ K +++ L + N L+ + ++ + S
Sbjct: 1075 VLQ-TMEKVTKEKDAIHQEKIETLASLENSRQTNEKLQNELDMLK-QNNLKNEEELTKSK 1132
Query: 625 PRGAVGDDKVKRAPELVEFYQSLMKREAKKDASLLTSSTSNA------ADTRSNVIA--E 676
+ + KV+ EL + +++L A+K L N +R V + +
Sbjct: 1133 ELLNLENKKVE---ELKKEFEALKLAAAQKSQQLAALQEENVKLAEELGRSRDEVTSHQK 1189
Query: 677 IENRSSFLLAVKADVETQGDFVMSLATEVRAASFSKIEDVVAFVNWLDEELSFLSDERAV 736
+E S L +++ + + E RA+ I D A + DEEL L +E V
Sbjct: 1190 LEEERSVLNNQLLEMKKRESTLKKEIDEERASLQKSISDTSALITQKDEELEKLRNEITV 1249
Query: 737 LKHFDWPEGKSDALREASFE--YQDLMKLEKQVSNFTDDPKLPCEDAL 782
L+ E S ++ + D +KLE++V N K E L
Sbjct: 1250 LR----GENASAKTLQSVVKTLESDKLKLEEKVKNLEQKLKAKSEQPL 1293
Score = 49.7 bits (117), Expect = 4e-05
Identities = 56/249 (22%), Positives = 112/249 (44%), Gaps = 21/249 (8%)
Query: 46 ETEMAKNGSDSEIEWLRNVVEELEEREMKLQSELLEYYSLKE-QVPVIEEFQRQLRIKSV 104
ET + S E L+N ++ L++ +K + EL + L + +EE +++ +
Sbjct: 1095 ETLASLENSRQTNEKLQNELDMLKQNNLKNEEELTKSKELLNLENKKVEELKKEFEALKL 1154
Query: 105 EIDMLHMTIKSLQEENNKLQEEL---IHEASAKRELE----VARNKIKELQRQIKIIANQ 157
+ +LQEEN KL EEL E ++ ++LE V N++ E++++ + +
Sbjct: 1155 AAAQKSQQLAALQEENVKLAEELGRSRDEVTSHQKLEEERSVLNNQLLEMKKRESTLKKE 1214
Query: 158 TKGQLLLLKQKVSGLQAKEEEVVKKDAEIE---NNLKTVNDFEIEKKL--KTVNDLEIEA 212
+ L++ +S A + +KD E+E N + + K V LE +
Sbjct: 1215 IDEERASLQKSISDTSAL---ITQKDEELEKLRNEITVLRGENASAKTLQSVVKTLESDK 1271
Query: 213 VGLKRRNKELQHE---KRELTVKLNAAESRITELSSVTENEMIADAKSETGRLRHANEDL 269
+ L+ + K L+ + K E + + + I +++ ++E D + E L DL
Sbjct: 1272 LKLEEKVKNLEQKLKAKSEQPLTVTSPSGDIA--ANLLQDESAEDKQQEIDFLNSVIVDL 1329
Query: 270 QKQVEGLQM 278
Q++ E L +
Sbjct: 1330 QRRNEELNL 1338
Score = 35.4 bits (80), Expect = 0.70
Identities = 47/224 (20%), Positives = 93/224 (40%), Gaps = 35/224 (15%)
Query: 84 SLKEQVPVIEEFQRQLRIKSVEIDMLHMTIKSLQEENNKLQE-ELIHEASAKRELEVARN 142
+LKE+ IE+ + ++ E+ + +++E +++ H + +++ R
Sbjct: 357 ALKEKQQHIEQLLAERDLERAEVAKATSHVGEIEQELALVRDGHDRHVLEMEAKMDQLRA 416
Query: 143 KIKELQRQIKIIANQTKGQLLLLKQKVSGLQ--AKEEEVVKKDAEIENNLKTVNDFEIEK 200
++ R+ + NQ + + K+KV LQ +EE + K D E + L+ E+E+
Sbjct: 417 MVEAADREKVELLNQLEEE----KRKVEDLQFRVEEESITKGDLETQTKLEHARIKELEQ 472
Query: 201 KL-----------KTVNDLEIEAVGLKRRNKELQH-------EKRELTVKLNAAE----- 237
L + + D + V K R EL+ E EL +L +++
Sbjct: 473 SLLFEKTKADKLQRELEDTRVATVSEKSRIMELERDLALRVKEVAELRGRLESSKHIDDV 532
Query: 238 ----SRITELSSVTENEMIADAKSETGRLRHANEDLQKQVEGLQ 277
S + E+SS+ E +M A K + E + E L+
Sbjct: 533 DTSLSLLQEISSLQE-KMAAAGKEHQREMSSLKEKFESSEEALR 575
>MYH8_HUMAN (P13535) Myosin heavy chain, skeletal muscle, perinatal
(MyHC-perinatal)
Length = 1937
Score = 61.2 bits (147), Expect = 1e-08
Identities = 67/279 (24%), Positives = 127/279 (45%), Gaps = 40/279 (14%)
Query: 45 NETEMAKNGSD----SEIEWLRNVVEELEEREMKLQSELLEYYSLKEQVPVIEEFQRQLR 100
NE E+ N ++ + RN L+E ++ L L LKEQ+ ++E R+
Sbjct: 1626 NEMEIQLNHANRLAAESLRNYRNTQGILKETQLHLDDALRGQEDLKEQLAIVE---RRAN 1682
Query: 101 IKSVEIDMLHMTIKSLQEENNKLQEELIHEASAKRELEVARNKIKELQRQIKIIANQTKG 160
+ EI+ L T++ + ++EL+ A +++ L Q + N K
Sbjct: 1683 LLQAEIEELWATLEQTERSRKIAEQELLD----------ASERVQLLHTQNTSLINTKK- 1731
Query: 161 QLLLLKQKVSGLQAKEEEVVKKDAEIENNL-KTVNDF-----EIEKKLKTVNDLEIEAVG 214
L+ VS LQ++ EEV+++ E K + D E++K+ T LE
Sbjct: 1732 ---KLENDVSQLQSEVEEVIQESRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKN 1788
Query: 215 LKRRNKELQH---EKRELTVK-----LNAAESRITELSSVTENEMIADAKSETGRLRHAN 266
L++ K+LQH E +L +K + E+R+ EL ENE +A++ G +H
Sbjct: 1789 LEQTVKDLQHRLDEAEQLALKGGKKQIQKLEARVRELEGEVENEQKRNAEAVKGLRKH-- 1846
Query: 267 EDLQKQVEGLQMNRFSEVEELVYLRWVNACLRYELRNYK 305
+++V+ L + + ++ L+ + L+ ++++YK
Sbjct: 1847 ---ERRVKELTYQTEEDRKNVLRLQDLVDKLQAKVKSYK 1882
Score = 50.8 bits (120), Expect = 2e-05
Identities = 78/335 (23%), Positives = 145/335 (43%), Gaps = 51/335 (15%)
Query: 33 SEKTDDSKKHGGNETEMAKNGSDSEIEWLRNVVEELEEREMKLQSELLEYYSLKEQVPVI 92
+E T +K +E+ K+ D E+ L V +E E K+++ E L E + +
Sbjct: 937 AELTAKKRKLEDECSELKKDIDDLELT-LAKVEKEKHATENKVKNLTEEMAGLDETIAKL 995
Query: 93 EEFQRQLRIKSVEIDMLHMTIKSLQEENNKLQEELIHEASAKRE-----LEVARNKIKEL 147
+ ++ L+ + T+ LQ E +K+ ++ +A K E LE + + K+L
Sbjct: 996 SKEKKALQ------ETHQQTLDDLQAEEDKVN--ILTKAKTKLEQQVDDLEGSLEQEKKL 1047
Query: 148 QRQIKIIANQTKGQLLLLKQKVSGLQAKEEEVVKKDAEIENNLKTVNDFEIEKKLKTVND 207
+ ++ + +G L L ++ ++ ++++ D ++E +FEI + + D
Sbjct: 1048 RMDLERAKRKLEGDLKLAQESTMDMENDKQQL---DEKLEKK-----EFEISNLISKIED 1099
Query: 208 LEIEAVGLKRRNKELQHEKRELTVKLNA-------AESRITELSSVTENEMIADAKSETG 260
+ + L+++ KELQ EL ++ A AE + ++LS E E I++ E G
Sbjct: 1100 EQAVEIQLQKKIKELQARIEELGEEIEAERASRAKAEKQRSDLS--RELEEISERLEEAG 1157
Query: 261 RLRHANEDLQKQVEGLQMNRFSEVEELVYLRWVNACLRYE-----LRNYKAPSGKSLARD 315
A +L K+ E ++EE A L++E LR A S L
Sbjct: 1158 GATSAQVELNKKREAEFQKLRRDLEE--------ATLQHEAMVAALRKKHADSMAELGEQ 1209
Query: 316 LNNSFNPKSQEKAKQLMLEYAGSERGHGDTDIESN 350
++N ++ KQ LE SE D+ SN
Sbjct: 1210 IDN------LQRVKQ-KLEKEKSELKMETDDLSSN 1237
Score = 43.1 bits (100), Expect = 0.003
Identities = 46/201 (22%), Positives = 97/201 (47%), Gaps = 29/201 (14%)
Query: 101 IKSVEIDMLHMTIKSLQEENNKLQEELIHEASAKRELE-------VARNKIK-ELQRQIK 152
+KS E + T+K EE K ++EL + ++ELE +N ++ ++Q +
Sbjct: 843 LKSAETEKEMATMK---EEFQKTKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQSEAD 899
Query: 153 IIANQTKGQLLLLKQKVSGLQAKEEEVVKK-------DAEIENNLKTVNDFEIEKKLKTV 205
+A+ + L+K K+ L+AK +EV ++ +AE+ + + D E + K +
Sbjct: 900 SLADAEERCEQLIKNKIQ-LEAKIKEVTERAEEEEEINAELTAKKRKLED-ECSELKKDI 957
Query: 206 NDLEIEAVGLKRRNKELQHEKRELTVKLNAAESRITELS------SVTENEMIADAKSET 259
+DLE+ +++ +++ + LT ++ + I +LS T + + D ++E
Sbjct: 958 DDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLSKEKKALQETHQQTLDDLQAEE 1017
Query: 260 GR---LRHANEDLQKQVEGLQ 277
+ L A L++QV+ L+
Sbjct: 1018 DKVNILTKAKTKLEQQVDDLE 1038
Score = 40.8 bits (94), Expect = 0.017
Identities = 55/246 (22%), Positives = 114/246 (45%), Gaps = 29/246 (11%)
Query: 59 EWLRNVVE---ELEEREMKLQSELLEYYSLKEQVPVIEEFQRQLRIKSVEIDMLHMTIKS 115
EW + E ELE + + +S E + +K V EE QL + L K+
Sbjct: 1458 EWKQKYEETQAELEASQKESRSLSTELFKVKN---VYEESLDQL-------ETLRRENKN 1507
Query: 116 LQEENNKLQEEL------IHE-ASAKRELEVARNKIKELQRQIKIIANQTKGQLLLLKQK 168
LQ+E + L E++ IHE K+++E + +I+ + + +G++L ++ +
Sbjct: 1508 LQQEISDLTEQIAEGGKQIHELEKIKKQVEQEKCEIQAALEEAEASLEHEEGKILRIQLE 1567
Query: 169 VSGLQAK-EEEVVKKDAEIENNLKTVNDFEIEKKLKTVNDLEIEAVG-LKRRNKELQHEK 226
++ ++++ + ++ +KD EI+ + N + + +++ D EI + R K+++ +
Sbjct: 1568 LNQVKSEVDRKIAEKDEEIDQLKR--NHTRVVETMQSTLDAEIRSRNDALRVKKKMEGDL 1625
Query: 227 RELTVKLNAAESRITELSSVTENE--MIADAKSETGRLRHANEDLQKQ---VEGLQMNRF 281
E+ ++LN A E N ++ + + EDL++Q VE
Sbjct: 1626 NEMEIQLNHANRLAAESLRNYRNTQGILKETQLHLDDALRGQEDLKEQLAIVERRANLLQ 1685
Query: 282 SEVEEL 287
+E+EEL
Sbjct: 1686 AEIEEL 1691
Score = 38.9 bits (89), Expect = 0.063
Identities = 43/198 (21%), Positives = 90/198 (44%), Gaps = 26/198 (13%)
Query: 56 SEIEWLRNVVEELEEREMKLQSELLEYYSLKEQVPVIEEFQRQL-RIKSVEIDMLHMTIK 114
SE+E V++E E K + + + + E++ ++ L R+K L T+K
Sbjct: 1742 SEVE---EVIQESRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKK----NLEQTVK 1794
Query: 115 SLQEENNKLQEELIHEASAKRELEVARNKIKELQRQIKIIANQTKGQLLLLKQKVSGLQA 174
LQ ++ ++ + K++++ +++EL+ +++ N+ K + V GL+
Sbjct: 1795 DLQHRLDEAEQLALK--GGKKQIQKLEARVRELEGEVE---NEQKRNA----EAVKGLRK 1845
Query: 175 KEEEVVKKDAEIENNLKTVNDFE-----IEKKLKTVNDLEIEAVGLKRRN----KELQHE 225
E V + + E + K V + ++ K+K+ EA N ++LQHE
Sbjct: 1846 HERRVKELTYQTEEDRKNVLRLQDLVDKLQAKVKSYKRQAEEAEEQSNANLSKFRKLQHE 1905
Query: 226 KRELTVKLNAAESRITEL 243
E + + AES++ +L
Sbjct: 1906 LEEAEERADIAESQVNKL 1923
>TPM1_HYDAT (P39921) Tropomyosin I
Length = 253
Score = 60.8 bits (146), Expect = 2e-08
Identities = 51/184 (27%), Positives = 89/184 (47%), Gaps = 19/184 (10%)
Query: 120 NNKLQEELIHEASAKRE-------LEVARNKIKELQRQIKIIA---NQTKGQLLLLKQKV 169
N+K+ E + A+AK LE A ++ QR+I+++ N + +L+ KV
Sbjct: 21 NSKIDEADLRRANAKSSIVEASSRLEKAEGEVASFQRRIRLVQQNLNDVTERAQMLQSKV 80
Query: 170 SGLQAKEEEVVK-----KDAEIENNLKTVN-DFEIEKKLKTVNDLEIEAVGLKRRNKELQ 223
L+ E V + ++ E E++ K N + E++ K + + + EI+ +RRN +
Sbjct: 81 DNLEDVSESVKQARNQYEEEEAESDEKIQNLEEEVKVKKRELEENEIKLREKERRNVVVH 140
Query: 224 HEKRELTVKLNAAESRITELSSVTEN--EMIADAKSETGRLRHANEDLQKQVEGLQMNRF 281
+ TVK +A E RI L + +N E I D + GR ++ +Q+ L N+F
Sbjct: 141 RDIEAATVKADAIEKRIEILENTIKNGLESIKDLEEREGRTNEKENNIAEQISFLD-NKF 199
Query: 282 SEVE 285
EVE
Sbjct: 200 KEVE 203
Score = 35.4 bits (80), Expect = 0.70
Identities = 36/151 (23%), Positives = 64/151 (41%), Gaps = 26/151 (17%)
Query: 34 EKTDDSKKHGGNETEMAKNGSDSEIEWLRNVVE----ELEEREMKLQSE----LLEYYSL 85
E +S K N+ E + SD +I+ L V+ ELEE E+KL+ + ++ + +
Sbjct: 84 EDVSESVKQARNQYEEEEAESDEKIQNLEEEVKVKKRELEENEIKLREKERRNVVVHRDI 143
Query: 86 KEQVPVIEEFQRQLRIKSVEIDMLHMTIKSLQEE------------------NNKLQEEL 127
+ + ++++ I I +IK L+E +NK +E
Sbjct: 144 EAATVKADAIEKRIEILENTIKNGLESIKDLEEREGRTNEKENNIAEQISFLDNKFKEVE 203
Query: 128 IHEASAKRELEVARNKIKELQRQIKIIANQT 158
I +A+R V + IKE +IK + T
Sbjct: 204 IRIEAAERNCNVLEHNIKETSEEIKTWKHNT 234
>MEDB_GIALA (Q08014) Median body protein
Length = 857
Score = 60.8 bits (146), Expect = 2e-08
Identities = 67/296 (22%), Positives = 136/296 (45%), Gaps = 40/296 (13%)
Query: 9 NDFDDEILSEFESLLSEQTDFPLLSEKTDD-SKKHGGNETEMAKNGSDSEIEWLRNVVEE 67
N+ D++ E L+ E D + K D +++ ETE+ +N + ++
Sbjct: 440 NEDIDKLTFEKRQLVEELNDLREKTIKYDQLAREKAALETELKENSYN---------FDQ 490
Query: 68 LEEREMKLQSELLEYYSLKEQVPVIEEFQRQLRIKSVEIDMLHMTIKSLQEENNKLQEEL 127
L E++ +++S+L +L+E+ E R+LR+K E++ + I+ L E+ ++ EL
Sbjct: 491 LLEQKQQMRSDL---NALREKAADYERVDRELRLKDKELEEKNAEIERLLEDRRVMRTEL 547
Query: 128 IHEASAKRELEVARNKIKELQRQIKIIANQTKGQLLLLKQKVSGLQAKEEEVVKKDAEIE 187
+H + +++ + I+E + + + +A+ L+ ++S + EE ++K E E
Sbjct: 548 LHSKESATDVD---SLIQEKRLRDRELAH--------LRDRMSEYERVVEERIQK--EKE 594
Query: 188 NNLKTVNDFEIEKKLKTVNDLEIEAVGLKRRNKELQHEKRELTVKLNAAESRITELSSVT 247
NNL E+E++ +T E E L+ + EL RE + +
Sbjct: 595 NNLLKQRITELEQQQRTATVRETEMSALREKANELDGYNRERQAREH------------- 641
Query: 248 ENEMIADAKSETGRLRHANEDLQKQVEGLQMNRFSEVEELVYLRWVNACLRYELRN 303
E M+ D E+ +LR N + ++ L+ + +E+L Y + ELR+
Sbjct: 642 EINMLRDKALESDKLRQDNRVMAMELTELR-EKVQLLEKLQYEKRARDVEMLELRH 696
Score = 46.2 bits (108), Expect = 4e-04
Identities = 61/271 (22%), Positives = 114/271 (41%), Gaps = 32/271 (11%)
Query: 46 ETEMAKNGSDSEIEWLRNVVEELEEREMKLQSELLEYYSLKEQVPVIEEFQRQLRIKSVE 105
E + +N ++ + ++ + E KL ++ E L + +++ R + +
Sbjct: 383 ERSILRNEIQAKTTEIDTLISDRRALETKLLNKEAEVDQLLYEKQLLKTELNSYRGTNED 442
Query: 106 IDMLHMTIKSLQEENNKLQEELIHEASAKRELEVARNKIKELQ---RQIKIIANQTKGQL 162
ID L + L EE N L+E+ I RE ++KE Q+ Q + L
Sbjct: 443 IDKLTFEKRQLVEELNDLREKTIKYDQLAREKAALETELKENSYNFDQLLEQKQQMRSDL 502
Query: 163 LLLKQKVSG-------LQAKEEEVVKKDAEIENNL--KTVNDFEIEKKLKTVNDLEIEAV 213
L++K + L+ K++E+ +K+AEIE L + V E+ ++ D++
Sbjct: 503 NALREKAADYERVDRELRLKDKELEEKNAEIERLLEDRRVMRTELLHSKESATDVDSLIQ 562
Query: 214 GLKRRNKELQH-------------EKRELTVKLNAAESRITEL------SSVTENEMIAD 254
+ R++EL H E+ + + N + RITEL ++V E EM A
Sbjct: 563 EKRLRDRELAHLRDRMSEYERVVEERIQKEKENNLLKQRITELEQQQRTATVRETEMSA- 621
Query: 255 AKSETGRLRHANEDLQKQVEGLQMNRFSEVE 285
+ + L N + Q + + M R +E
Sbjct: 622 LREKANELDGYNRERQAREHEINMLRDKALE 652
Score = 45.4 bits (106), Expect = 7e-04
Identities = 48/231 (20%), Positives = 104/231 (44%), Gaps = 26/231 (11%)
Query: 55 DSEIEWLRNVVEELEER-EMKLQSELLEYYSLKEQVPVIEEFQRQ----------LRIKS 103
D E+ LR+ + E E E ++Q E E LK+++ +E+ QR LR K+
Sbjct: 568 DRELAHLRDRMSEYERVVEERIQKEK-ENNLLKQRITELEQQQRTATVRETEMSALREKA 626
Query: 104 VEIDMLHMTIKSLQEENNKLQEELIHEASAKRELEVARNKIKELQRQIKIIAN------Q 157
E+D + ++ + E N L+++ + +++ V ++ EL+ +++++
Sbjct: 627 NELDGYNRERQAREHEINMLRDKALESDKLRQDNRVMAMELTELREKVQLLEKLQYEKRA 686
Query: 158 TKGQLLLLKQKVSGLQAKEEEVVKKDAEIENNLKTVNDFE--------IEKKLKTVNDLE 209
++L L+ K + EE + + + VN+++ ++++LK ++D
Sbjct: 687 RDVEMLELRHKAMDVDTLVEEKQRLEMRLAELKIKVNNYDQLADDKARLQEQLKEMSDKL 746
Query: 210 IEAVGLKRRNKELQHEKRELTVKLNAAESRITELSSVTENEMIADAKSETG 260
IE + N+ L+ + +EL +K E E + + A + TG
Sbjct: 747 IEFEMIMDDNRRLKLQVKELDLKTANMEKLYEEYKKLEDQLKATKAMTSTG 797
Score = 41.6 bits (96), Expect = 0.010
Identities = 66/270 (24%), Positives = 114/270 (41%), Gaps = 48/270 (17%)
Query: 92 IEEFQRQL------RIKSVEIDMLHMTIKSLQEENNKLQEELIHEASAKRELEVARNKIK 145
IE QRQ+ E+ ML +++L+ + + + A +REL+ R + +
Sbjct: 248 IENIQRQIDDANSSASSEHELRMLRAEVETLRAQKSIVTRLEAENADLRRELQDIRGRAQ 307
Query: 146 ELQRQIKIIANQTK-------GQLLLLKQKVSGLQAKEEEVVKKDA---------EIENN 189
E+ + ANQ + LL+QK+ + E + + DA +E+
Sbjct: 308 EMSASQRYSANQAQELQEKAMQAEELLQQKIELRRQLHEALERADAGEAALRDKRRLEDE 367
Query: 190 LK------TVNDFEIEKKLKTVNDLEIEAVGLKRRNKELQHEKRELTVKLNAAESRITEL 243
+K T NDF E+ + N+++ + + L ++R L KL E+ + +L
Sbjct: 368 IKGLQLRLTENDFTKERSILR-NEIQAKTTEI----DTLISDRRALETKLLNKEAEVDQL 422
Query: 244 SSVTENEMIADAKSETGRLRHANEDLQKQVEGLQMNRFSEVEELVYLRWVNACLRY-ELR 302
+ E +++ K+E R NED+ K L + VEEL LR ++Y +L
Sbjct: 423 --LYEKQLL---KTELNSYRGTNEDIDK----LTFEKRQLVEELNDLR--EKTIKYDQLA 471
Query: 303 NYKAPSGKSLARDLNNSFNPKSQEKAKQLM 332
KA L NS+N + KQ M
Sbjct: 472 REKAALETELK---ENSYNFDQLLEQKQQM 498
Score = 38.1 bits (87), Expect = 0.11
Identities = 107/541 (19%), Positives = 209/541 (37%), Gaps = 70/541 (12%)
Query: 67 ELEEREMKLQSELLEYYSLKEQVPVIEEFQRQLRIKSVEIDMLHMTIKSLQEENNKLQEE 126
EL E+ +LQ+EL E E E QL+ + E+ +L +E L+
Sbjct: 123 ELYEQRCQLQAELRELQEFSENPAAAVEEIMQLKAQIDELKYGASNHNALVQEKRDLERH 182
Query: 127 LIH--------EASAKRELEVARNKIKELQRQIKII------ANQTKGQLLLLKQK--VS 170
L + +E++ R +I++ +R + + ++ + QL ++++ S
Sbjct: 183 LADLRLSRQDTNSRLPQEIDRLRAEIEDEKRNLPHMDDLQRQRDELQRQLDTIRRRGNTS 242
Query: 171 GLQAKEEEVVKK------DAEIENNLKTVN-DFEIEKKLKT-VNDLEIEAVGLKRRNKEL 222
G+ A+ E + ++ A E+ L+ + + E + K+ V LE E L+R +++
Sbjct: 243 GVMAEIENIQRQIDDANSSASSEHELRMLRAEVETLRAQKSIVTRLEAENADLRRELQDI 302
Query: 223 QHEKRELTVKLNAAESRITEL-SSVTENEMIADAKSETGRLRHA--------------NE 267
+ +E++ + ++ EL + E + K E R H
Sbjct: 303 RGRAQEMSASQRYSANQAQELQEKAMQAEELLQQKIELRRQLHEALERADAGEAALRDKR 362
Query: 268 DLQKQVEGLQMNRFSE---VEELVYLRWVNACLRYELRNYKAPSGKSLARDLNNSFNPKS 324
L+ +++GLQ+ R +E +E LR E+ + + LN
Sbjct: 363 RLEDEIKGLQL-RLTENDFTKERSILRNEIQAKTTEIDTLISDRRALETKLLNKEAEVDQ 421
Query: 325 QEKAKQLMLEYAGSERGHGDTDIESNFSHDHSSPGSEDLDNAYINSPTYKYSNLSKKTSL 384
KQL+ S RG + + F DL T KY L+++ +
Sbjct: 422 LLYEKQLLKTELNSYRGTNEDIDKLTFEKRQLVEELNDL-----REKTIKYDQLAREKAA 476
Query: 385 IQKLKKWNKNNDSSAFSSPARSLSIGSPCRVSTSYRPRNTLESLMLRNAHDAVAITTFEQ 444
++ K N N + S + R + R E L L++ E+
Sbjct: 477 LETELKENSYNFDQLLEQKQQMRSDLNALREKAADYERVDRE-LRLKDKE-------LEE 528
Query: 445 KEHKPTHSPETPFLPSLRKVSSSDDILDSVSASFQLMSKSVDRSLDEKYPAYKDLHKLAL 504
K + E L R+V ++ + SA+ VD + EK ++L L
Sbjct: 529 K------NAEIERLLEDRRVMRTELLHSKESAT------DVDSLIQEKRLRDRELAHLRD 576
Query: 505 AREKQLKEKAEKARGEKFGDNSNLNTTKAEEERSTSL--DSELTQVNEKACVSDGLNKQS 562
+ + E+ + EK + T+ E+++ T+ ++E++ + EKA DG N++
Sbjct: 577 RMSEYERVVEERIQKEKENNLLKQRITELEQQQRTATVRETEMSALREKANELDGYNRER 636
Query: 563 E 563
+
Sbjct: 637 Q 637
Score = 32.7 bits (73), Expect = 4.5
Identities = 40/174 (22%), Positives = 74/174 (41%), Gaps = 32/174 (18%)
Query: 6 NLANDFDDEILSEFESLLSEQTDFPLLSEKTDDSKKHGGNETEMAKNGSDSEIEWLRNVV 65
NL E+ + + +T+ L EK ++ G N A+ + EI LR+
Sbjct: 596 NLLKQRITELEQQQRTATVRETEMSALREKANELD--GYNRERQAR---EHEINMLRDKA 650
Query: 66 EELEEREMKLQSELLEYYSLKEQVPVIEEFQRQLRIKSVE-IDMLH--MTIKSLQEE--- 119
E ++ + +E L+E+V ++E+ Q + R + VE +++ H M + +L EE
Sbjct: 651 LESDKLRQDNRVMAMELTELREKVQLLEKLQYEKRARDVEMLELRHKAMDVDTLVEEKQR 710
Query: 120 ------------NN---------KLQEELIHEASAKRELEVARNKIKELQRQIK 152
NN +LQE+L + E E+ + + L+ Q+K
Sbjct: 711 LEMRLAELKIKVNNYDQLADDKARLQEQLKEMSDKLIEFEMIMDDNRRLKLQVK 764
>TMF1_HUMAN (P82094) TATA element modulatory factor (TMF)
Length = 1093
Score = 60.1 bits (144), Expect = 3e-08
Identities = 67/280 (23%), Positives = 134/280 (46%), Gaps = 17/280 (6%)
Query: 56 SEIEWLRNVVEELEEREMKLQSELLEYYSLKEQVPVIEEFQRQLRIKSVEIDMLHMTIKS 115
SE E + VE L E+ K +++LL SL ++ ++EE L+ + + +I S
Sbjct: 442 SEKEDVCKTVEFLNEKLEKREAQLL---SLSKEKALLEEAFDNLKDEMFRVKEESSSISS 498
Query: 116 LQEE-NNKLQEELIHEASAKRELEVARNKIKELQRQI--KIIANQTKGQLLLLKQKVSGL 172
L++E ++ E A +E + A+ +IK ++ ++ ++ +++T L +++ GL
Sbjct: 499 LKDEFTQRIAEAEKKVQLACKERDAAKKEIKNIKEELATRLNSSETADLLKEKDEQIRGL 558
Query: 173 QAKEEEVVKKDAEIENNLKTV--NDFEIEKKLKTVNDLEIEAVGLKRRNKELQHEKRELT 230
+ E++ K+ N +K + D E E + +N +K +ELQH K+ L
Sbjct: 559 MEEGEKLSKQQLHNSNIIKKLRAKDKENENMVAKLNK------KVKELEEELQHLKQVLD 612
Query: 231 VKLNAAESRITELSSVTENEMIADAKSETGRLRHANEDLQKQVEGLQMNRFSEVEELVYL 290
K + + + N M+ + + GRL+ ++L+++ +Q S +EL L
Sbjct: 613 GKEEVEKQHRENIKKL--NSMVERQEKDLGRLQVDMDELEEKNRSIQAALDSAYKELTDL 670
Query: 291 RWVNACLRYELRNYKAPSGKSLARDLNNSFNPKSQEKAKQ 330
NA E + A S + A++ ++ K+QE+A+Q
Sbjct: 671 HKANAAKDSEAQE-AALSREMKAKEELSAALEKAQEEARQ 709
Score = 57.4 bits (137), Expect = 2e-07
Identities = 119/594 (20%), Positives = 240/594 (40%), Gaps = 67/594 (11%)
Query: 10 DFDDEILSEFES-LLSEQTDFPLLSEKTDDSKKHGGNETEMAKNGSDSEIEWLRNVVEEL 68
+F +E L + E+ LLS + LL E D+ K +E K S S + +
Sbjct: 452 EFLNEKLEKREAQLLSLSKEKALLEEAFDNLK----DEMFRVKEESSSISSLKDEFTQRI 507
Query: 69 EEREMKLQSELLEYYSLKEQVPVIEEFQRQLRIKSVEI-DMLHMT---IKSLQEENNKLQ 124
E E K+Q E + K+++ I+E + R+ S E D+L I+ L EE KL
Sbjct: 508 AEAEKKVQLACKERDAAKKEIKNIKE-ELATRLNSSETADLLKEKDEQIRGLMEEGEKLS 566
Query: 125 EELIHEASAKRELEVARNKIKELQRQIKIIANQTKGQLLLLKQKVSGLQAKEEEVVKKDA 184
++ +H ++ ++L + + + ++ + + +L LKQ + G +EEV K+
Sbjct: 567 KQQLHNSNIIKKLRAKDKENENMVAKLNKKVKELEEELQHLKQVLDG----KEEVEKQHR 622
Query: 185 EIENNLKTVNDFEIEKKLKTVNDLEIEAVGLKRRNKELQ----HEKRELTVKLNAAESRI 240
E N+K +N +E++ K + L+++ L+ +N+ +Q +ELT A ++
Sbjct: 623 E---NIKKLNSM-VERQEKDLGRLQVDMDELEEKNRSIQAALDSAYKELTDLHKANAAKD 678
Query: 241 TELSSVTENEMIADAKSETGRLRHANEDLQKQVE-----------GLQMNRFSEVEELVY 289
+E + + + + L A E+ ++Q E LQ + + Y
Sbjct: 679 SEAQEAALSREMKAKEELSAALEKAQEEARQQQETLAIQVGDLRLALQRTEQAAARKEDY 738
Query: 290 LRWVNACLRYELRNYK----------APSGKSLARDLNNSFNPKSQEKAKQLMLEYAGSE 339
LR L+ L+ + + + + L R + N + + LE S+
Sbjct: 739 LRHEIGELQQRLQEAENRNQELSQSVSSTTRPLLRQIENLQATLGSQTSSWEKLEKNLSD 798
Query: 340 R-GHGDTDIESNFSHDHSSPGSEDLDNAYINSPTYKYSNLSKKTSLIQKLKKWNKN---- 394
R G T + + + ++ + ++S + S L ++ S Q + KN
Sbjct: 799 RLGESQTLLAAAVERERAATEELLANKIQMSSMESQNSLLRQENSRFQAQLESEKNRLCK 858
Query: 395 --NDSSAFSSPARSL------SIGSPCRVSTSYRPRNTLESLMLRNAHDAVAIT--TFEQ 444
++++ + +L ++ + T + +E + + T T ++
Sbjct: 859 LEDENNRYQVELENLKDEYVRTLEETRKEKTLLNSQLEMERMKVEQERKKAIFTQETIKE 918
Query: 445 KEHKPTHSPETPFLPSLRKVSSSDDILDSVSASFQLMSKSVDRSLDEKYPAYKDLHKLAL 504
KE KP TP + +S D + + SF +S D S + K H A
Sbjct: 919 KERKPFSVSSTPTMSRSSSISGVD--MAGLQTSFLSQDESHDHSFGPMPISAKWKHLYAA 976
Query: 505 AREKQLKEKAEKARGE---KFGDNSNLNTTKAEEERSTSLDSE----LTQVNEK 551
++ + E + + + G+ ++L E++ S+ +E LT N++
Sbjct: 977 CKDGSRIKHIENLQSQLKLREGEITHLQLEIGNLEKTRSIMAEELVKLTNQNDE 1030
Score = 41.2 bits (95), Expect = 0.013
Identities = 32/112 (28%), Positives = 61/112 (53%), Gaps = 6/112 (5%)
Query: 92 IEEFQRQLRIKSVEIDMLHMTIKSLQEENNKLQEELIHEASAKRELEVARNKIKELQRQI 151
IE Q QL+++ EI L + I +L++ + + EEL+ + ELE +I +L+ Q+
Sbjct: 986 IENLQSQLKLREGEITHLQLEIGNLEKTRSIMAEELVKLTNQNDELEEKVKEIPKLRTQL 1045
Query: 152 KIIANQTKGQLLLLKQKVSGLQAKEEEVVKKDAE-IENNLKTVNDFEIEKKL 202
+ + +Q +L ++ G +A+E E ++ D E ++N KT D + + L
Sbjct: 1046 RDL-DQRYNTIL----QMYGEKAEEAEELRLDLEDVKNMYKTQIDELLRQSL 1092
Score = 32.0 bits (71), Expect = 7.7
Identities = 22/96 (22%), Positives = 43/96 (43%), Gaps = 1/96 (1%)
Query: 482 SKSVDRSLDEKYPAYKDLHKLALAREKQLKEKAEKARGEKFGDNSNLNTTKAEEERSTSL 541
++S+ +LD Y DLHK A++ + +E A +R K + + KA+EE
Sbjct: 653 NRSIQAALDSAYKELTDLHKANAAKDSEAQE-AALSREMKAKEELSAALEKAQEEARQQQ 711
Query: 542 DSELTQVNEKACVSDGLNKQSEDVKDFDNQTITEMK 577
++ QV + + + +D+ I E++
Sbjct: 712 ETLAIQVGDLRLALQRTEQAAARKEDYLRHEIGELQ 747
>RA50_SULTO (Q96YR5) DNA double-strand break repair rad50 ATPase
Length = 879
Score = 60.1 bits (144), Expect = 3e-08
Identities = 71/329 (21%), Positives = 149/329 (44%), Gaps = 46/329 (13%)
Query: 6 NLANDFDDEILSEFESLLSEQTDFPLLSEKTDDSKKHGGNETEMAKNGSDSEIEWLRNVV 65
N+ + +D + E E + D L+E+ + +K + D E V
Sbjct: 209 NIKRELEDLNIKE-EKERKKYEDIVKLNEEEEKKEKRYVELISLLNKLKDDISELREEVK 267
Query: 66 EE--LEEREMKLQSELLEYYSLKEQVPVIEEFQRQLRIKSVEIDMLHMTIKSLQEENNKL 123
+E L E + KL+ ++LE L E+ I E Q ++++ + ++K+++ L
Sbjct: 268 DENRLREEKEKLEKDILEKDKLIEEKEKIIEAQNKIKLAQEK----EKSLKTIKINLTDL 323
Query: 124 QEELIHEASAKRELEVARNKIKELQRQIKIIANQTKGQLLLLKQKVSGLQAKEEEVVKKD 183
+E+L KRELE K E++ +++ + + + + L ++ L+ K E+ +
Sbjct: 324 EEKL----KRKRELEEDYKKYIEIKGELEELEEKER-KFNSLSDRLKSLKIKLSEI---E 375
Query: 184 AEIENNLKTVNDFEIEKKLKTVNDLEIEAVGLKRRNKELQHEKRELTVKLNAAESRITEL 243
++I N ++N E++K+L+ +N+ L +N+ E+ +L +L + RI EL
Sbjct: 376 SKISNRKISINIEELDKELQKLNE------DLNNKNQ----EREKLASQLGEIKGRIEEL 425
Query: 244 SSVTENEMIADAKSETGRL-----RHANEDLQKQVEGLQMNRFSEVEELVYLRWVNACLR 298
N+++ + G + R ++D +++++ + + E++EL N +
Sbjct: 426 -----NKLLGNLNQVKGNVCPVCGRELSDDHKRKIQNEIIEKLKELDEL------NKKFK 474
Query: 299 YELRNYKAPSGKSLARDLNNSFNPKSQEK 327
E+ L +LN N KS+EK
Sbjct: 475 LEINKI-----NGLISELNQIINKKSKEK 498
Score = 35.8 bits (81), Expect = 0.53
Identities = 43/240 (17%), Positives = 107/240 (43%), Gaps = 49/240 (20%)
Query: 69 EEREMKLQSELLEYYSLKEQVPVIEEFQRQLRIKSVEIDMLHMTIKSLQEENNKLQEELI 128
++ + K+Q+E++E LKE + ++F+ ++ + I L+ I +E + L
Sbjct: 449 DDHKRKIQNEIIE--KLKELDELNKKFKLEINKINGLISELNQIINKKSKEKDIAIRNLA 506
Query: 129 HEASAKRELEVARNKIKELQRQIKIIANQTKGQLLLLKQKVSGLQAKEEEVVKK------ 182
+ + + R +I+E++ +I+ ++ + + + LK++ L+ K EE +K
Sbjct: 507 DYNNLLTQQQELRKEIEEIENEIERLSIYHE-KYIRLKEEEKNLKPKYEEYLKYYDVTEE 565
Query: 183 ------------DAEIENNLKTVNDFEIEKKLKTVNDLEIEAVGLKRRNKELQHEKRELT 230
+ EIE + V ++ + + D+E K +Q
Sbjct: 566 KIRELERQKIELEKEIEEIMNKVREYYNTDLTQKIRDIE----------KRIQ------- 608
Query: 231 VKLNAAESRITELSSVTENEMIADAKSETGRLRHANEDLQKQVEGLQM-----NRFSEVE 285
++ E+++ EL + ++A ++ +++ E+++K + LQ+ NRF +++
Sbjct: 609 -EIKGKENKLRELDT-----LLAKIETAKQKIKQNEEEIKKLTDELQLLNFDPNRFQQIK 662
>RA50_SULSO (Q97WH0) DNA double-strand break repair rad50 ATPase
Length = 864
Score = 59.7 bits (143), Expect = 3e-08
Identities = 72/304 (23%), Positives = 132/304 (42%), Gaps = 55/304 (18%)
Query: 16 LSEFESLLSEQTDF------------PLLSEKTDDSKKHGGNETEMAKNGSDSEIEWLRN 63
L++ ESL+SE+ + P+ D+ K ++ K S I L
Sbjct: 401 LAKVESLISEKNEIINNISQVEGETCPVCGRPLDEEHKQ-----KIIKEAK-SYILQLEL 454
Query: 64 VVEELEEREMKLQSEL----LEYYSLKEQVPVIEEFQRQLRIKSVEIDMLHMTIKSLQ-- 117
ELEE K+ +EL EY L + RQL+ + EI+ LH I+SL+
Sbjct: 455 NKNELEEELKKITNELNKIEREYRRLSNNKASYDNVMRQLKKLNEEIENLHSEIESLKNI 514
Query: 118 -EENNKLQEELIHEASAKRELEVARNKIKELQRQIKIIANQTKGQLLLLKQKVSGLQAKE 176
EE K+ EE+ ++K + ++ TK +L + K+ ++ K+
Sbjct: 515 DEEIKKINEEV--------------KELKLYYEEFMRLSKYTKEELDKKRVKLDEMKKKK 560
Query: 177 EEVVKKDAEIENNLKTVNDFEIEKKLKTVNDLEIEAVGLKRRN----------KELQHEK 226
EE+ K+ +E+ LK ++ +E K+ + + ++ +K++ K LQ E
Sbjct: 561 EEIEKEMRGLESELKGLDRKALESKILDLENKRVKLDEMKKKKGILEDYIRQVKLLQEEV 620
Query: 227 RELTVKLNAA---ESRITELSSVTE--NEMIADAKSETGRLRHANEDLQKQVEGLQMNRF 281
+ L ++N E+R EL + + N + + ++ R+ E L+K +E + NR
Sbjct: 621 KNLREEVNIIQFDENRYNELKTSLDAYNLSLKEKENRKSRIEGELESLEKDIEEIS-NRI 679
Query: 282 SEVE 285
+ E
Sbjct: 680 ANYE 683
Score = 48.1 bits (113), Expect = 1e-04
Identities = 102/508 (20%), Positives = 206/508 (40%), Gaps = 65/508 (12%)
Query: 55 DSEIEWLRNVVEELEEREMKLQSELLEYYSLKEQVPVIEEFQRQLRIKSVEIDMLHMTIK 114
+ E+ L +EEL + Q+E ++ L++++ +E R +++K + ++L +
Sbjct: 248 EGELNELNRSIEELRK-----QTENMD--QLEKEINELENL-RNIKLKFEKYEVLAKSHT 299
Query: 115 SLQEENNKLQEELIHEASA---KRELEVARNKIKELQRQIKIIANQTKGQLLLLKQKVSG 171
+ L++E+ A K ELE K KEL+R+++ + + + Q L LK +
Sbjct: 300 EMSANVINLEKEIEEYEKAIRRKEELEPKYLKYKELERKLEELQPKYQ-QYLKLKSDLDS 358
Query: 172 LQAKEEEVVKKDAEIENNLKTVNDFEIEKKLKTVNDLEIEAVGLKRRNKELQHEKRELTV 231
+E + K +E+ N++ VN +E+K++ ++ + + L EK E+
Sbjct: 359 KLNLKERLEKDASELSNDIDKVN--SLEQKVEETRKKQLNLRAQLAKVESLISEKNEIIN 416
Query: 232 KLNAAESRI-----TELSSVTENEMIADAKSETGRLRHANEDLQKQVEGLQMNRFSEVEE 286
++ E L + ++I +AKS +L +L+++++ + N +++E
Sbjct: 417 NISQVEGETCPVCGRPLDEEHKQKIIKEAKSYILQLELNKNELEEELKKI-TNELNKIER 475
Query: 287 LVYLRWVNACLRYE--LRNYKAPSG--KSLARDLNNSFN-----PKSQEKAKQLMLEYAG 337
Y R N Y+ +R K + ++L ++ + N K E+ K+L L Y
Sbjct: 476 -EYRRLSNNKASYDNVMRQLKKLNEEIENLHSEIESLKNIDEEIKKINEEVKELKLYYEE 534
Query: 338 SERGHGDTDIESNFSHDHSSPGSEDLDNAYINSPTYKYSNLSKKTSLIQK----LKKWNK 393
R S E+LD + K + KK I+K L+ K
Sbjct: 535 FMR--------------LSKYTKEELDKKRV-----KLDEMKKKKEEIEKEMRGLESELK 575
Query: 394 NNDSSAFSSPARSLSIGSPCRVSTSYRPRNTLESLM---------LRNAHDAVAITTFEQ 444
D A S L ++ + + LE + ++N + V I F++
Sbjct: 576 GLDRKALESKILDLE-NKRVKLDEMKKKKGILEDYIRQVKLLQEEVKNLREEVNIIQFDE 634
Query: 445 KEHKPTHSPETPFLPSLRKVSSSDDILDSVSASFQLMSKSVDRSLDEKYPAYKDLHKLAL 504
+ + + SL++ + ++ S + + + + KD K+
Sbjct: 635 NRYNELKTSLDAYNLSLKEKENRKSRIEGELESLEKDIEEISNRIANYELQLKDREKIIN 694
Query: 505 AREKQLKEKAEKARGEKFGDNSNLNTTK 532
A K EK A GE+ + + TTK
Sbjct: 695 AINK--LEKIRSALGERKLQSYIIMTTK 720
Score = 45.4 bits (106), Expect = 7e-04
Identities = 88/352 (25%), Positives = 164/352 (46%), Gaps = 41/352 (11%)
Query: 2 GSI-MNLANDFDD-EILSEFESLLSEQ---TDFPLLSEKT---DDSKKHGGNETEMAKNG 53
GS+ + L+N+ D EI+ + S ++ FP+ T ++ +K G + ++A +
Sbjct: 67 GSVTLYLSNEKDKIEIIRDIRSTTEDRLIRNQFPIARSATVVSNEIEKILGIDKDIALST 126
Query: 54 SDSEIEWLRNVVEELEEREMK-LQSELLEYYSLKEQVPVIEEFQRQLRIKSVEIDMLHMT 112
L ++E +E K L+ EL+E + + P++E F++ L K E+D +
Sbjct: 127 IIVRQGELDKILENFQEIMGKILKLELIEKL-IDSRGPIVE-FRKNLENKLRELDRIEQD 184
Query: 113 IKSLQEENNKLQEELIHEASAKRELEVARNKIKELQRQIKIIANQ------TKGQLLLLK 166
+ ++ ++E+ K++ E ++IK L+++IK I +Q + Q L L
Sbjct: 185 YNNFKK---TVEEKRARVLELKKDKEKLEDEIKNLEKRIKDIKDQFDEYEKKRNQYLKL- 240
Query: 167 QKVSGLQAKEEEVVKKDAEIENNLK-TVNDFEIEKKLKTVNDLEIEAVGLKRRNKELQHE 225
+ L+ KE E+ + + IE K T N ++EK+ +N+LE RN +L+ E
Sbjct: 241 --TTTLKIKEGELNELNRSIEELRKQTENMDQLEKE---INELE------NLRNIKLKFE 289
Query: 226 KRELTVKLNAAESR--ITELSSVTENEMIADAKSETGRLRHANEDLQKQVEGLQMNRFSE 283
K E+ K + S I + E E K E ++L++++E LQ +
Sbjct: 290 KYEVLAKSHTEMSANVINLEKEIEEYEKAIRRKEELEPKYLKYKELERKLEELQ----PK 345
Query: 284 VEELVYLRW-VNACLRYELRNYKAPSGKSLARDLNNSFNPKSQE-KAKQLML 333
++ + L+ +++ L + R K S S D NS K +E + KQL L
Sbjct: 346 YQQYLKLKSDLDSKLNLKERLEKDASELSNDIDKVNSLEQKVEETRKKQLNL 397
Score = 32.3 bits (72), Expect = 5.9
Identities = 24/81 (29%), Positives = 37/81 (45%), Gaps = 4/81 (4%)
Query: 480 LMSKSVDRSLDEKYPAYKDLHKLA--LAREKQLKEKAEKARGEKFGDNSNLNT--TKAEE 535
L K ++R L+E P Y+ KL L + LKE+ EK E D +N+ K EE
Sbjct: 330 LKYKELERKLEELQPKYQQYLKLKSDLDSKLNLKERLEKDASELSNDIDKVNSLEQKVEE 389
Query: 536 ERSTSLDSELTQVNEKACVSD 556
R L+ ++ +S+
Sbjct: 390 TRKKQLNLRAQLAKVESLISE 410
>MYS2_DICDI (P08799) Myosin II heavy chain, non muscle
Length = 2116
Score = 59.7 bits (143), Expect = 3e-08
Identities = 126/584 (21%), Positives = 233/584 (39%), Gaps = 110/584 (18%)
Query: 31 LLSEKTDDSKKHGGNETEM--AKNGSDSEIEWLRNVVEELEEREMKLQSELLEYYSLKEQ 88
+L E D + GG + + K +S++E LRN + EL+ KL+ +K
Sbjct: 1123 MLEEMKDQLESTGGEKKSLYDLKVKQESDMEALRNQISELQSTIAKLE-------KIKST 1175
Query: 89 VP-VIEEFQRQLRIKSVEIDMLHMTIKSLQEENNKLQEELIHEASAKRELEVARNKIK-- 145
+ + Q +L + + + K ++ + +L E +AK+ L+ + K++
Sbjct: 1176 LEGEVARLQGELEAEQLAKSNVEKQKKKVELDLEDKSAQLAEETAAKQALDKLKKKLEQE 1235
Query: 146 --ELQRQIKIIANQT----------KGQLLLLKQKVSGLQAKEEEVVKKDAEIENNLKTV 193
E+Q Q+ N+ + LK ++ Q ++ + KK +E+ LK V
Sbjct: 1236 LSEVQTQLSEANNKNVNSDSTNKHLETSFNNLKLELEAEQKAKQALEKKRLGLESELKHV 1295
Query: 194 ND-FEIEKKLKTVNDLEIEAVGLKRRNKELQHEKRELTVKLNAAESRITELSSVTENEMI 252
N+ E EKK K N E V L++ EL+ + E A++ +TE + E+E+
Sbjct: 1296 NEQLEEEKKQKESN--EKRKVDLEKEVSELKDQIEEEV----ASKKAVTEAKNKKESEL- 1348
Query: 253 ADAKSETGRLRHANEDLQKQVEGLQMNRFSEVEELVYLRWVNACLRYELRNYKAP----- 307
+++++Q + +R VE+L L+ N LR +
Sbjct: 1349 --------------DEIKRQYADVVSSRDKSVEQLKTLQAKNEELRNTAEEAEGQLDRAE 1394
Query: 308 -SGKSLARDLNNSFNPKSQEKAKQLMLEYAGSERGHGDTDIESNFSHDHSSPGSEDLDNA 366
S K DL + +E AK++ E A + +TD S S +LD+A
Sbjct: 1395 RSKKKAEFDLEEAVKNLEEETAKKVKAEKAMKK---AETDYRSTKS---------ELDDA 1442
Query: 367 YINSPTYKYSNLSKKTSLIQKLKKWNKNNDSSAFSSPARSLSIGSPCRVSTSYRPRNTLE 426
N+S + + ++K+ N+ S RS+ + R +++ + + T E
Sbjct: 1443 ---------KNVSSEQYV--QIKRLNEE------LSELRSVLEEADERCNSAIKAKKTAE 1485
Query: 427 SLMLRNAHDAVAITTFEQKEHKPTHSPETPFLPSLRKVSSSDDILDSVSASFQLMSKSVD 486
S + + A + K + + E +V+ ++ L+ S +V+
Sbjct: 1486 SALESLKDEIDAANNAKAKAERKSKELEV-------RVAELEESLEDKSG-------TVN 1531
Query: 487 RSLDEKYPAYKDLHKLALAREKQLKEKAEKARGEKFGDNSNLNTTKAEEERSTSLDSELT 546
K A D + L RE + + K+ D NT K + L++++
Sbjct: 1532 VEFIRKKDAEIDDLRARLDRETESRIKS---------DEDKKNTRK----QFADLEAKVE 1578
Query: 547 QVNEKACVSDGLNKQSE-DVKDFDNQTITEMK-LFKIEKRPPRL 588
+ + D L K+ E D+ D Q TE K KIEK +L
Sbjct: 1579 EAQREVVTIDRLKKKLESDIIDLSTQLDTETKSRIKIEKSKKKL 1622
Score = 57.8 bits (138), Expect = 1e-07
Identities = 160/775 (20%), Positives = 304/775 (38%), Gaps = 115/775 (14%)
Query: 62 RNVVEELEERE---MKLQSELLEYY--------SLKEQVPVIEEFQRQLRIKSVEIDMLH 110
RN +E++E+E ++L+S L + SLK+ + + QRQL+ +
Sbjct: 824 RNFEKEIKEKEREILELKSNLTDSTTQKDKLEKSLKDTESNVLDLQRQLKAEK------- 876
Query: 111 MTIKSLQEENNKLQEELIHEASAKRELEVARNKIKELQRQIKIIANQTKGQLLLLKQKVS 170
T+K++ + + L+ + KRELE+ ++ + K+ + Q +++KV
Sbjct: 877 ETLKAMYDSKDALEAQ-------KRELEIRVEDMESELDEKKLALENLQNQKRSVEEKVR 929
Query: 171 GLQAKEEEVVKKDAEIENNL-KTVNDFEIE-KKLKTVNDLEIEAVG-LKRRNKELQHEKR 227
L EE ++++ ++ N L K +E E +++K VND + + + L++ ELQ E
Sbjct: 930 DL----EEELQEEQKLRNTLEKLKKKYEEELEEMKRVNDGQSDTISRLEKIKDELQKEVE 985
Query: 228 ELTVKLNAAESRITELSSVTENEMIADAKSETGRLRHANEDLQKQVEGLQMNRFSEVEEL 287
ELT E ++ + G L LQ +++ L + SE ++
Sbjct: 986 ELT-------------------ESFSEESKDKGVLEKTRVRLQSELDDLTVRLDSETKD- 1025
Query: 288 VYLRWVNACLRYELRNYKAPSGKSLARDLNNSFNPKSQEKAKQLMLEYAGSERGHGDTDI 347
+ EL K K L +L + E A +L E A + T++
Sbjct: 1026 ----------KSELLRQK----KKLEEELKQVQEALAAETAAKLAQEAANKKLQGEYTEL 1071
Query: 348 ESNFSHDHSSPGSEDLDNAYINSPTYKYSN-LSKKTSLIQKLKKWNKNNDSSAFSSPARS 406
F+ + ++ + + + S +N L ++ L+K K D+ +
Sbjct: 1072 NEKFNSEVTARSNVEKSKKTLESQLVAVNNELDEEKKNRDALEKKKKALDAMLEEMKDQL 1131
Query: 407 LSIGSPCRVSTSYRPRNTLESLMLRNAHDAVAITTFEQKEHKPTHSPETPFLP-SLRKVS 465
S G + + + + LRN + T + ++ K T E L L
Sbjct: 1132 ESTGGEKKSLYDLKVKQESDMEALRNQISELQSTIAKLEKIKSTLEGEVARLQGELEAEQ 1191
Query: 466 SSDDILDSVSASFQLMSKSVDRSLDEKYPAYKDLHKLALAREKQLKE------KAEKARG 519
+ ++ +L + L E+ A + L KL E++L E +A
Sbjct: 1192 LAKSNVEKQKKKVELDLEDKSAQLAEETAAKQALDKLKKKLEQELSEVQTQLSEANNKNV 1251
Query: 520 EKFGDNSNLNTT---------------KAEEERSTSLDSELTQVNEKACVSDGLNKQSED 564
N +L T+ +A E++ L+SEL VNE+ + K+S +
Sbjct: 1252 NSDSTNKHLETSFNNLKLELEAEQKAKQALEKKRLGLESELKHVNEQ-LEEEKKQKESNE 1310
Query: 565 VKDFD-NQTITEMKLFKIEKRPPRLPRPPPKPSDGAPVSNSLNEI--PYAPSVPSPPPPP 621
+ D + ++E+K E+ + K + L+EI YA V S
Sbjct: 1311 KRKVDLEKEVSELKDQIEEEVASKKAVTEAKNKK----ESELDEIKRQYADVVSSRDKSV 1366
Query: 622 GSLPRGAVGDDKVKRAPELVEFYQSLMKREAKKDASLLTSSTSNAADTRSNVIAEIENRS 681
L +++++ E E +R KK L + N E +
Sbjct: 1367 EQLKTLQAKNEELRNTAEEAEGQLDRAERSKKKAEFDLEEAVKNLE----------EETA 1416
Query: 682 SFLLAVKADVETQGDFVMSLATEVRAASFSKIEDVVAFVNWLDEELSFLSDERAVLKHFD 741
+ A KA + + D+ S +E+ A E V + L+EELS L R+VL+ D
Sbjct: 1417 KKVKAEKAMKKAETDY-RSTKSELDDAKNVSSEQYVQ-IKRLNEELSEL---RSVLEEAD 1471
Query: 742 WPEGKSDALREASFEYQDLMKLEKQVSNFTDDPKLPCEDALQKMYSLLEKLEQSV 796
E + A++ L L+ ++ + ++ K E +++ + +LE+S+
Sbjct: 1472 --ERCNSAIKAKKTAESALESLKDEI-DAANNAKAKAERKSKELEVRVAELEESL 1523
Score = 55.8 bits (133), Expect = 5e-07
Identities = 111/561 (19%), Positives = 235/561 (41%), Gaps = 44/561 (7%)
Query: 46 ETEMAKNGSDSEIEWLRNVVE-ELEEREMKLQSELLEYYSLKEQVPVIEEFQRQLRIKSV 104
ET A S +E + +E +E+ E +L + L +L+ Q +EE R L +
Sbjct: 877 ETLKAMYDSKDALEAQKRELEIRVEDMESELDEKKLALENLQNQKRSVEEKVRDLEEELQ 936
Query: 105 EIDMLHMTIKSLQEENNKLQEELIHEASAKRELEVARNKIK-ELQRQIKII----ANQTK 159
E L T++ L+++ + EE+ + + KIK ELQ++++ + + ++K
Sbjct: 937 EEQKLRNTLEKLKKKYEEELEEMKRVNDGQSDTISRLEKIKDELQKEVEELTESFSEESK 996
Query: 160 GQLLLLKQKVSGLQAKEEEVVKKDAEIENNLKTVND-FEIEKKLKTVNDLEIEAVGLK-- 216
+ +L K +V ++ V+ D+E ++ + + ++E++LK V + K
Sbjct: 997 DKGVLEKTRVRLQSELDDLTVRLDSETKDKSELLRQKKKLEEELKQVQEALAAETAAKLA 1056
Query: 217 --RRNKELQHEKRELTVKLNA---AESRITELSSVTENEMIADAKSETGRLRHANEDLQK 271
NK+LQ E EL K N+ A S + + E++++A +E + + L+K
Sbjct: 1057 QEAANKKLQGEYTELNEKFNSEVTARSNVEKSKKTLESQLVA-VNNELDEEKKNRDALEK 1115
Query: 272 QVEGLQMNRFSEVEELVYLRWVNACLRYELRNYKAPSGKSLARDLNNSFNPKSQ-EKAKQ 330
+ + L E+++ + Y+L+ + ++L ++ + ++ EK K
Sbjct: 1116 KKKALDA-MLEEMKDQLESTGGEKKSLYDLKVKQESDMEALRNQISELQSTIAKLEKIKS 1174
Query: 331 LMLEYAGSERGHGDTDIESNFSHDHSSPGSE-DLD--NAYINSPTYKYSNLSK-KTSLIQ 386
+ +G + + + + + E DL+ +A + T L K K L Q
Sbjct: 1175 TLEGEVARLQGELEAEQLAKSNVEKQKKKVELDLEDKSAQLAEETAAKQALDKLKKKLEQ 1234
Query: 387 KLKKW--------NKNNDSSAFSSPARSLSIGSPCRVSTSYRPRNTLESLMLRNAHDAVA 438
+L + NKN +S + + + + + + LE L +
Sbjct: 1235 ELSEVQTQLSEANNKNVNSDSTNKHLETSFNNLKLELEAEQKAKQALEKKRLGLESELKH 1294
Query: 439 ITTFEQKEHKPTHSPETPFLPSLRKVSSSDDILDSVSASFQLMSKSVDR---SLDEKYPA 495
+ ++E K S E + ++VS D ++ AS + ++++ ++ LDE
Sbjct: 1295 VNEQLEEEKKQKESNEKRKVDLEKEVSELKDQIEEEVASKKAVTEAKNKKESELDEIKRQ 1354
Query: 496 YKDL----------HKLALAREKQLKEKAEKARGEKFGDNSNLNTTKAEEERSTSLDSEL 545
Y D+ K A+ ++L+ AE+A G+ D + + KAE + ++ +
Sbjct: 1355 YADVVSSRDKSVEQLKTLQAKNEELRNTAEEAEGQL--DRAERSKKKAEFDLEEAVKNLE 1412
Query: 546 TQVNEKACVSDGLNKQSEDVK 566
+ +K + K D +
Sbjct: 1413 EETAKKVKAEKAMKKAETDYR 1433
Score = 54.3 bits (129), Expect = 1e-06
Identities = 117/615 (19%), Positives = 238/615 (38%), Gaps = 101/615 (16%)
Query: 13 DEILSEFESLLSEQTDFPLLSEKTDDSKKHGGNETEMAKNGSDSEIEWLRNVVEELEERE 72
++ LSE ++ LSE + + S+ T+ KH E + N E+E + + LE++
Sbjct: 1233 EQELSEVQTQLSEANNKNVNSDSTN---KH----LETSFNNLKLELEAEQKAKQALEKKR 1285
Query: 73 MKLQSELLEYYSLKEQVPVIEEFQRQLRIKSVEIDMLHMTIKSLQEENNKLQEELIHEAS 132
+ L+SEL E+ +E + ++ L++E ++L++++ E +
Sbjct: 1286 LGLESELKHVNEQLEEEKKQKESNEKRKV-------------DLEKEVSELKDQIEEEVA 1332
Query: 133 AKRELEVARNK----IKELQRQIKIIANQTKGQLLLLKQKVSGLQAKEEEVVKKDAEIEN 188
+K+ + A+NK + E++RQ + + + LK LQAK EE+ E E
Sbjct: 1333 SKKAVTEAKNKKESELDEIKRQYADVVSSRDKSVEQLKT----LQAKNEELRNTAEEAEG 1388
Query: 189 NL------KTVNDFEIEKKLKTVNDLEIEAVGLKRRNKELQHEKRELTVKLNAAESRITE 242
L K +F++E+ +K + + + V ++ K+ + + R + +S + +
Sbjct: 1389 QLDRAERSKKKAEFDLEEAVKNLEEETAKKVKAEKAMKKAETDYR-------STKSELDD 1441
Query: 243 LSSVTENEMIADAKSETGRLRHANEDLQKQVEGLQMNRFSEVEELVYLRWVNACLRYELR 302
+V+ + + +++ NE+L + L+ E +E N+ ++ +
Sbjct: 1442 AKNVSSEQYV--------QIKRLNEELSELRSVLE-----EADER-----CNSAIKAKKT 1483
Query: 303 NYKAPSGKSLARDLNNSFNPKSQEKAKQLMLEYAGSERGHGD-----------------T 345
A D N+ K++ K+K+L + A E D
Sbjct: 1484 AESALESLKDEIDAANNAKAKAERKSKELEVRVAELEESLEDKSGTVNVEFIRKKDAEID 1543
Query: 346 DIESNFSHDHSSPGSEDLDNAYINSPTYKYSNLSKKTSLIQK----LKKWNKNNDSSAFS 401
D+ + + S D D + ++++L K Q+ + + K +S
Sbjct: 1544 DLRARLDRETESRIKSDEDK---KNTRKQFADLEAKVEEAQREVVTIDRLKKKLESDIID 1600
Query: 402 SPARSLSIGSPCRVSTSYRPRNTLESLMLRNAHDAVAITTFEQKEHKPTHSPETPFLPSL 461
+ L + R+ + ++L R A + + +++ K L
Sbjct: 1601 L-STQLDTETKSRIKIEKSKKKLEQTLAERRAAEEGSSKAADEEIRKQVWQEVDELRAQL 1659
Query: 462 RKVSSSDDILDSVSASFQLMSKSVDRSLDEKYPAYKDLHKLALAREKQLK------EKAE 515
++ + + S V L+++ A L K A E +L+ E+ E
Sbjct: 1660 DSERAALNASEKKIKSLVAEVDEVKEQLEDEILAKDKLVKAKRALEVELEEVRDQLEEEE 1719
Query: 516 KARGEKFGDNSNLNTT--------KAEEERSTSLDSELTQVNEKACVSDGLNKQSEDVKD 567
+R E L T AE E++T LD ++ + D L KQ ED K
Sbjct: 1720 DSRSELEDSKRRLTTEVEDIKKKYDAEVEQNTKLDEAKKKLTDDV---DTLKKQLEDEKK 1776
Query: 568 FDNQTITEMKLFKIE 582
N++ K + E
Sbjct: 1777 KLNESERAKKRLESE 1791
Score = 50.4 bits (119), Expect = 2e-05
Identities = 66/295 (22%), Positives = 134/295 (45%), Gaps = 56/295 (18%)
Query: 3 SIMNLANDFDDEILSEFESLLSEQTDFPLLSEKTDDSKKHGGNETEMAKNGSDSEIEWLR 62
++ NL + ++ +E +++ +TD+ + DD+K + K ++ E+ LR
Sbjct: 1407 AVKNLEEETAKKVKAE-KAMKKAETDYRSTKSELDDAKNVSSEQYVQIKRLNE-ELSELR 1464
Query: 63 NVVEELEER------EMKLQSELLEYYSLKEQVPVIEEFQRQLRIKSVEIDMLHMTI-KS 115
+V+EE +ER K LE SLK+++ + + KS E+++ + +S
Sbjct: 1465 SVLEEADERCNSAIKAKKTAESALE--SLKDEIDAANNAKAKAERKSKELEVRVAELEES 1522
Query: 116 LQEENNKLQEELIHEASAKRELEVARNKIKELQRQIKIIANQTKGQLLLLKQKVSGLQAK 175
L++++ + E I + A +I +L+ + L +
Sbjct: 1523 LEDKSGTVNVEFIRKKDA---------EIDDLRAR---------------------LDRE 1552
Query: 176 EEEVVKKDAEIENNLKTVNDFEIEKKLKTVNDLEIEAVGLKRRNKELQHEKRELTVKLNA 235
E +K D + +N K D E + V + + E V + R K+L+ + +L+ +L+
Sbjct: 1553 TESRIKSDEDKKNTRKQFADLEAK-----VEEAQREVVTIDRLKKKLESDIIDLSTQLDT 1607
Query: 236 -AESRI-TELSSVTENEMIADAK-SETGRLRHANEDLQKQVEGLQMNRFSEVEEL 287
+SRI E S + +A+ + +E G + A+E+++KQV + EV+EL
Sbjct: 1608 ETKSRIKIEKSKKKLEQTLAERRAAEEGSSKAADEEIRKQV-------WQEVDEL 1655
Score = 48.1 bits (113), Expect = 1e-04
Identities = 48/196 (24%), Positives = 90/196 (45%), Gaps = 18/196 (9%)
Query: 92 IEEFQRQLRIKSVEIDMLHMTIKSLQEENNKLQEELIHEASAKRELEVARNKIKELQRQI 151
++E + QL + ++ IKSL E ++++E+L E AK +L A+ ++ ++
Sbjct: 1652 VDELRAQLDSERAALNASEKKIKSLVAEVDEVKEQLEDEILAKDKLVKAKRALEVELEEV 1711
Query: 152 KIIANQTKGQLLLLKQKVSGLQAKEEEVVKK-DAEIENNLKTVNDFEIEKKLKTVNDLEI 210
+ + + L+ L + E++ KK DAE+E N K E K K +D++
Sbjct: 1712 RDQLEEEEDSRSELEDSKRRLTTEVEDIKKKYDAEVEQNTKL-----DEAKKKLTDDVD- 1765
Query: 211 EAVGLKRRNKELQHEKRELTVKLNAAESRITELSSVTENEMIADAKSETGRLRHANEDLQ 270
K+L+ EK+ KLN +E L S E + +A +E A +D +
Sbjct: 1766 ------TLKKQLEDEKK----KLNESERAKKRLESENE-DFLAKLDAEVKNRSRAEKDRK 1814
Query: 271 KQVEGLQMNRFSEVEE 286
K + L+ ++ +E
Sbjct: 1815 KYEKDLKDTKYKLNDE 1830
Score = 43.1 bits (100), Expect = 0.003
Identities = 57/260 (21%), Positives = 118/260 (44%), Gaps = 39/260 (15%)
Query: 50 AKNGSDSEIEWLRNVVEELEEREMKLQSELL--------------EYYSLKEQVPVIEEF 95
A N S+ +I +++V E++E + +L+ E+L E +++Q+ E+
Sbjct: 1665 ALNASEKKI---KSLVAEVDEVKEQLEDEILAKDKLVKAKRALEVELEEVRDQLEEEEDS 1721
Query: 96 QRQL----RIKSVEIDMLHMTIKSLQEENNKLQE---ELIHEASA-KRELEVARNKIKEL 147
+ +L R + E++ + + E+N KL E +L + K++LE + K+ E
Sbjct: 1722 RSELEDSKRRLTTEVEDIKKKYDAEVEQNTKLDEAKKKLTDDVDTLKKQLEDEKKKLNES 1781
Query: 148 QRQIKIIANQTKGQLLLLKQKVSGLQAKEEEVVKKDAEIENNLKTVNDFEIEKKLKTVND 207
+R K + ++ + L L +V E++ K + ++++ +ND + T
Sbjct: 1782 ERAKKRLESENEDFLAKLDAEVKNRSRAEKDRKKYEKDLKDTKYKLND-----EAATKTQ 1836
Query: 208 LEIEAVGLKRRNKELQHEKRELTVKLNAAESRITELSSVTENEMIADAKSETGRLRHANE 267
EI A L+ + EL+ + + K A+ L +N + A + E G+++ E
Sbjct: 1837 TEIGAAKLEDQIDELRSKLEQEQAKATQADKSKKTLEGEIDN-LRAQIEDE-GKIKMRLE 1894
Query: 268 DLQKQVEGLQMNRFSEVEEL 287
++ +EG E+EEL
Sbjct: 1895 KEKRALEG-------ELEEL 1907
Score = 42.4 bits (98), Expect = 0.006
Identities = 60/272 (22%), Positives = 107/272 (39%), Gaps = 47/272 (17%)
Query: 16 LSEFESLLSEQTDFPLLSEKTDDSKKHGGNETEMAKNGSDSEIEWLRNVVEELEEREMKL 75
L E L E+ D + +DSK+ E E K D+E+E +N +L+E + KL
Sbjct: 1708 LEEVRDQLEEEEDS---RSELEDSKRRLTTEVEDIKKKYDAEVE--QNT--KLDEAKKKL 1760
Query: 76 QSELLEYYSLKEQVPVIEEFQRQLRIKSVEIDMLHMTIKSLQEENNKLQEELIHEASAKR 135
+ ++ ++QL + +++ K L+ EN +L E +
Sbjct: 1761 TDD-------------VDTLKKQLEDEKKKLNESERAKKRLESENEDFLAKLDAEVKNRS 1807
Query: 136 ELEVARNKIKELQRQIKIIAN-------QTKGQLLLLKQKVSGLQAKEEEVVKKDAEIEN 188
E R K ++ + K N QT+ L+ ++ L++K E+ K + +
Sbjct: 1808 RAEKDRKKYEKDLKDTKYKLNDEAATKTQTEIGAAKLEDQIDELRSKLEQEQAKATQADK 1867
Query: 189 NLKTVNDFEIEKKLKTVNDLEIEAVGLKRRNKELQHEKRELTVKLNAAES---------R 239
+ KT+ EI+ + D + L++ + L+ E EL + AE R
Sbjct: 1868 SKKTLEG-EIDNLRAQIEDEGKIKMRLEKEKRALEGELEELRETVEEAEDSKSEAEQSKR 1926
Query: 240 ITELS----------SVTENEMIADAKSETGR 261
+ EL + E+ DAKS R
Sbjct: 1927 LVELELEDARRNLQKEIDAKEIAEDAKSNLQR 1958
>EEA1_HUMAN (Q15075) Early endosome antigen 1 (Endosome-associated
protein p162) (Zinc finger FYVE domain containing protein
2)
Length = 1411
Score = 59.7 bits (143), Expect = 3e-08
Identities = 117/604 (19%), Positives = 234/604 (38%), Gaps = 78/604 (12%)
Query: 27 TDFPLLSEKTDDSKKHGGNETEMAKNGSDSEIEWLRNVVEELEEREMKLQSELLEYYSLK 86
T ++ K D ++H K + + L EELE + KL+++ LE + K
Sbjct: 688 TQLDQVTAKLQDKQEHCSQLESHLKEYKEKYLS-LEQKTEELEGQIKKLEADSLEVKASK 746
Query: 87 EQVPVIEEFQRQLRIK------------SVEIDMLHMTIKSLQEENNKLQEELIHEASAK 134
EQ + QRQL +E +++ T LQ+++ L+ +
Sbjct: 747 EQALQDLQQQRQLNTDLELRATELSKQLEMEKEIVSSTRLDLQKKSEALESIKQKLTKQE 806
Query: 135 RELEVARNKIKELQRQIKIIANQTKGQLLLLKQKVSGLQAKEEEVVKKDAEIENNLKTVN 194
E ++ + + L ++ KI + ++ ++ ++ ++E ++ + + +++ L V+
Sbjct: 807 EEKQILKQDFETLSQETKIQHEELNNRIQTTVTELQKVKMEKEALMTELSTVKDKLSKVS 866
Query: 195 D--------FEIEKKLKTVNDLEIE----------AVGLKRRNKELQHEKRELTVKLNAA 236
D FE E + L++E V ++ KE + K+ L + A+
Sbjct: 867 DSLKNSKSEFEKENQKGKAAILDLEKTCKELKHQLQVQMENTLKEQKELKKSLEKEKEAS 926
Query: 237 ESRITELSSVTE------NEMIADAKSE------TGRLRHANEDLQKQVEGLQMNRFSEV 284
EL+S+ E N + + K E L+ ++E +KQ+E LQ
Sbjct: 927 HQLKLELNSMQEQLIQAQNTLKQNEKEEQQLQGNINELKQSSEQKKKQIEALQ------- 979
Query: 285 EELVYLRWVNACLRYELRNYKAPSGKSLARD------LNNSFNPKSQEKAKQLMLEYAGS 338
EL L +L+ + + LA + L N++ KSQE KQL ++ G
Sbjct: 980 GELKIAVLQKTELENKLQQQLTQAAQELAAEKEKISVLQNNYE-KSQETFKQLQSDFYGR 1038
Query: 339 ERGHGDTDIESNFSHDHSSPGSEDLDNAYINSPTYKYSNLSKKTSLIQKLKKWNKNNDSS 398
E T + + S EDL + + + + LIQ+LK +
Sbjct: 1039 ESELLATRQDLKSVEEKLSLAQEDLIS--------NRNQIGNQNKLIQELKTAKATLEQ- 1089
Query: 399 AFSSPARSLSIGSPCRVSTSYRPRNTLESLMLRNAHDAVA----ITTFEQKE-HKPTHSP 453
S + + C+ + +L+ L N +A I ++KE K
Sbjct: 1090 --DSAKKEQQLQERCKALQDIQKEKSLKEKELVNEKSKLAEIEEIKCRQEKEITKLNEEL 1147
Query: 454 ETPFLPSLRKVSSSDD---ILDSVSASFQLMSKSVDRSLDEKYPAYKDLHKLALAREKQL 510
++ L S++++++ D +L Q + S+ +++++ + L E++L
Sbjct: 1148 KSHKLESIKEITNLKDAKQLLIQQKLELQGKADSLKAAVEQEKRNQQILKDQVKKEEEEL 1207
Query: 511 KEKAEKARGEKFGDNSNLNT-TKAEEERSTSLDSELTQVNEK-ACVSDGLNKQSEDVKDF 568
K++ + + + K EE L ++T +NE V V +
Sbjct: 1208 KKEFIEKEAKLHSEIKEKEVGMKKHEENEAKLTMQITALNENLGTVKKEWQSSQRRVSEL 1267
Query: 569 DNQT 572
+ QT
Sbjct: 1268 EKQT 1271
Score = 53.9 bits (128), Expect = 2e-06
Identities = 79/357 (22%), Positives = 156/357 (43%), Gaps = 64/357 (17%)
Query: 20 ESLLSEQTDFPLLSEKTDD---SKKH----------GGNETEMAKNGSDSEIEWLRNVVE 66
E+LL ++ D+ L EK ++ SKK+ + + + S++ + + +
Sbjct: 309 ENLLKKEQDYTKLEEKHNEESVSKKNIQATLHQKDLDCQQLQSRLSASETSLHRIHVELS 368
Query: 67 ELEEREMKLQSELLE----YYSLKEQVPVI-----EEFQRQLRIKSVEIDMLHM----TI 113
E E KL+ EL E Y LK + + E+ Q L+++S EI+ LH T
Sbjct: 369 EKGEATQKLKEELSEVETKYQHLKAEFKQLQQQREEKEQHGLQLQS-EINQLHSKLLETE 427
Query: 114 KSLQEENNKLQEE-------LIHEASAKRELEVARNKIKELQRQIKIIANQTKGQLLLLK 166
+ L E + +L+E+ L+ + +L++ ++++E ++ + + + QL K
Sbjct: 428 RQLGEAHGRLKEQRQLSSEKLMDKEQQVADLQLKLSRLEEQLKEKVTNSTELQHQLDKTK 487
Query: 167 QKVSGLQAKEEEVVKKDAEIENNLKTVNDFEIEKKLKTVNDLEIEAVGLKRRNKELQHEK 226
Q+ QA ++ K E +N+L+ V +I K + + +LE K L+ E+
Sbjct: 488 QQHQEQQALQQSTTAKLREAQNDLEQVLR-QIGDKDQKIQNLEALLQKSKENISLLEKER 546
Query: 227 RELTVKLNAAESRITELSSVTE---------NEMIADAKSETGRLRHANEDLQKQVEGLQ 277
+L K+ A E L+ + E ++ K+++ + A E+L QV+
Sbjct: 547 EDLYAKIQAGEGETAVLNQLQEKNHTLQEQVTQLTEKLKNQSESHKQAQENLHDQVQ--- 603
Query: 278 MNRFSEVEELVYLRWVNACLRYELRNYKAPSGKSLARDLNNSFNPKSQEKAKQLMLE 334
E+ +LR + S ++ +LN+ N +S+EK QL ++
Sbjct: 604 -------EQKAHLR---------AAQDRVLSLETSVNELNSQLN-ESKEKVSQLDIQ 643
Score = 42.7 bits (99), Expect = 0.004
Identities = 110/561 (19%), Positives = 233/561 (40%), Gaps = 84/561 (14%)
Query: 52 NGSDSEIEWLRNVVEELEEREMKLQSELLE--YYS--LKEQVPVIEEFQRQ-------LR 100
+G +S + R+ V L + LQ+ L E +YS LK+++ + Q+Q +
Sbjct: 72 HGGESNLALKRDDVTLLRQEVQDLQASLKEEKWYSEELKKELEKYQGLQQQEAKPDGLVT 131
Query: 101 IKSVEIDMLHMTIKSLQEENNKLQE--ELIHEASAKRELEVARNKIK-ELQRQIKIIANQ 157
S E+ L ++ Q EN +++ +L + +A+ E+A K K + +R ++ A
Sbjct: 132 DSSAELQSLEQQLEEAQTENFNIKQMKDLFEQKAAQLATEIADIKSKYDEERSLREAA-- 189
Query: 158 TKGQLLLLKQKVSGLQAKEEEVVKKDAEIENNLKT-------VNDFEIEKK--LKTVNDL 208
+QKV+ L E + K+A + +LKT + D + KK ++ +
Sbjct: 190 --------EQKVTRLT----EELNKEATVIQDLKTELLQRPGIEDVAVLKKELVQVQTLM 237
Query: 209 EIEAVGLKRRNKELQHEKRELTVKLNAAESRITELSSVTEN--EMIADAKSETGRLRHAN 266
+ + +R +++L+ E ++L + ++E+ I++L S + +A E +L+ +
Sbjct: 238 DNMTLERERESEKLKDECKKLQSQYASSEATISQLRSELAKGPQEVAVYVQELQKLKSSV 297
Query: 267 EDLQKQVEGLQMNRFSEVEELVYLRWVNACLRYELRNYKAPSGKSLARDLNNSFNPKSQE 326
+L ++ + L N + ++ L E N ++ S K++ L+ +
Sbjct: 298 NELTQKNQTLTENLLKKEQDYTKLE--------EKHNEESVSKKNIQATLH-----QKDL 344
Query: 327 KAKQLMLEYAGSERGHGDTDIESNFSHDHSSPGSEDLDNAYINSPTYKYSNLSKKTSLIQ 386
+QL + SE +E + + + E+L KY +L + +Q
Sbjct: 345 DCQQLQSRLSASETSLHRIHVELSEKGEATQKLKEELSEVET-----KYQHLKAEFKQLQ 399
Query: 387 KLKKWNKNNDSSAFS--SPARSLSIGSPCRVSTSY---RPRNTLESLMLRNAHDAVAITT 441
+ ++ + + S + S + + ++ ++ + + L S L + VA
Sbjct: 400 QQREEKEQHGLQLQSEINQLHSKLLETERQLGEAHGRLKEQRQLSSEKLMDKEQQVADLQ 459
Query: 442 F------EQKEHKPTHSPETPFLPSLRKVSSSDDILDSVSASFQLMSKSVD-----RSLD 490
EQ + K T+S E K + S + +L D R +
Sbjct: 460 LKLSRLEEQLKEKVTNSTELQHQLDKTKQQHQEQQALQQSTTAKLREAQNDLEQVLRQIG 519
Query: 491 EKYPAYKDLHKLALAREKQLKEKAEKARGEKF-------GDNSNLNTTKAEEERSTSLDS 543
+K ++L L L + K+ EK R + + G+ + LN +E++ +L
Sbjct: 520 DKDQKIQNLEAL-LQKSKENISLLEKEREDLYAKIQAGEGETAVLNQL---QEKNHTLQE 575
Query: 544 ELTQVNEKACVSDGLNKQSED 564
++TQ+ EK +KQ+++
Sbjct: 576 QVTQLTEKLKNQSESHKQAQE 596
>CENF_HUMAN (P49454) CENP-F kinetochore protein (Centromere protein F)
(Mitosin) (AH antigen)
Length = 3210
Score = 59.7 bits (143), Expect = 3e-08
Identities = 77/358 (21%), Positives = 156/358 (43%), Gaps = 20/358 (5%)
Query: 61 LRNVVEELEEREMKLQSELLEYYSLKEQVPVIEEFQRQLRIKSVEIDMLHMTIKSLQEEN 120
LRN+ ELE++ LQS+ SL++ + V++ + L E+++ M S E+
Sbjct: 2654 LRNLTVELEQKIQVLQSKNA---SLQDTLEVLQSSYKNLEN---ELELTKMDKMSFVEKV 2707
Query: 121 NKLQEELIHEASAKRELEVARNKIKELQRQIKIIANQTKGQLLLLKQKVSGLQAKEEEVV 180
NK+ + E +RE+ K ELQ ++ N+ G+L LL +++ + + +E+
Sbjct: 2708 NKMTAK---ETELQREMHEMAQKTAELQEELSGEKNRLAGELQLLLEEIKSSKDQLKELT 2764
Query: 181 KKDAEIENNLKTVNDFEIEKKLKTVNDLEIEAVGLKRRNKELQHEKREL-TVKLNAAESR 239
+++E++ +L ++ ++EK+ K EI L+ E +H+ L T K E +
Sbjct: 2765 LENSELKKSLDCMHKDQVEKEGKVRE--EIAEYQLRLHEAEKKHQALLLDTNKQYEVEIQ 2822
Query: 240 ITELSSVTENEMIADAKSETGRLRHANEDLQKQVEG-LQMNRFSEVEELVYLRWVNACLR 298
++ E ++ K E L+ + E+L ++ Q+ + ++ L++VN +
Sbjct: 2823 TYREKLTSKEECLSSQKLEIDLLKSSKEELNNSLKATTQILEELKKTKMDNLKYVN---Q 2879
Query: 299 YELRNYKAPSGKSLARDLNNSFNPKSQEKAKQLMLEYAGSERGHGDTDIESNFSH--DHS 356
+ N +A L + + K+L A E+ T +++
Sbjct: 2880 LKKENERAQGKMKLLIKSCKQLEEEKEILQKELSQLQAAQEKQKTGTVMDTKVDELTTEI 2939
Query: 357 SPGSEDLDNAYINSPTY--KYSNLSKKTSLIQKLKKWNKNNDSSAFSSPARSLSIGSP 412
E L+ + Y KY +L ++K K+ + + S ++ S GSP
Sbjct: 2940 KELKETLEEKTKEADEYLDKYCSLLISHEKLEKAKEMLETQVAHLCSQQSKQDSRGSP 2997
Score = 51.2 bits (121), Expect = 1e-05
Identities = 69/278 (24%), Positives = 124/278 (43%), Gaps = 30/278 (10%)
Query: 54 SDSEIEWLRNVVEELEEREMKLQSELLEYYSLKEQVPV-IEEFQRQLRIKSVEIDMLHMT 112
S +E+E L+ +EE+ + +L+ S KE + I+E Q QL E+D L +
Sbjct: 2276 SKAEVETLKTQIEEMARSLKVFELDLVTLRSEKENLTKQIQEKQGQLS----ELDKLLSS 2331
Query: 113 IKSLQEENNKLQEELIHEASAKRELEVARNKIKELQRQIKIIANQTKGQLLLLKQKVSGL 172
KSL EE K Q E+ + +K +E+ +N++KEL + + G ++K L
Sbjct: 2332 FKSLLEE--KEQAEIQIKEESKTAVEMLQNQLKELNEAVAALC----GDQEIMKATEQSL 2385
Query: 173 QAKEEEVVKKDAEIENNLKTVNDFEIEKKLKTVNDLEIEAVGLKRRNKELQHEKRELTVK 232
EE E+ L+ IEK + E + + + ++ KE +H L +
Sbjct: 2386 DPPIEE--------EHQLRN----SIEKLRARLEADEKKQLCVLQQLKESEHHADLLKGR 2433
Query: 233 LNAAESRITELSSVTENEMIADAKSETGRLRHANEDLQKQVEGLQMNRFSEVEELVYLRW 292
+ E R E++ + +A++ G + E L+ ++EG+ + ++V +R
Sbjct: 2434 VENLE-RELEIARTNQEHAALEAENSKGEV----ETLKAKIEGMTQSLRGLELDVVTIRS 2488
Query: 293 VNACLRYELRNYKAPSGKSLARDLNNSFNPKSQEKAKQ 330
L EL+ K S +N+SF QEK ++
Sbjct: 2489 EKEDLTNELQ--KEQERISELEIINSSFENILQEKEQE 2524
Score = 49.3 bits (116), Expect = 5e-05
Identities = 65/281 (23%), Positives = 116/281 (41%), Gaps = 44/281 (15%)
Query: 20 ESLLSEQTDFPLLSEKTDDSKKHGGNETEMAKNGSDSEIEWLRNVVEELEEREMKLQSEL 79
E L +Q F L ++ K E + AKN + NV LQ+EL
Sbjct: 398 EELSRQQRSFQTLDQECIQMKARLTQELQQAKN--------MHNV----------LQAEL 439
Query: 80 LEYYSLKEQVPV-IEEFQRQL-------RIKSVEIDMLHMTIKSLQEENNKLQEELIHEA 131
+ S+K+Q+ +EEF+++L + ++ + L +++ +++ENN L+ +A
Sbjct: 440 DKLTSVKQQLENNLEEFKQKLCRAEQAFQASQIKENELRRSMEEMKKENNLLKSHSEQKA 499
Query: 132 SAKRELEVARNKIKELQRQIKIIANQTKGQLLLLKQKVSGLQAKEEEVVKKDAEIENNLK 191
LE IK+ Q + A + K + +E + +D + + N +
Sbjct: 500 REVCHLEAELKNIKQCLNQSQNFAEEMKA------------KNTSQETMLRDLQEKIN-Q 546
Query: 192 TVNDFEIEKKLKTVNDLEIEAVGLKRRNKELQHEKRELTVKLNAAESRITELSSV----- 246
N +EK V DLE + + K+ +H +L KL+ E L S
Sbjct: 547 QENSLTLEKLKLAVADLEKQRDCSQDLLKKREHHIEQLNDKLSKTEKESKALLSALELKK 606
Query: 247 TENEMIADAKSETGRLRHANEDLQKQVEGLQMNRFSEVEEL 287
E E + + K+ + NE L Q+E + N S++ L
Sbjct: 607 KEYEELKEEKTLFSCWKSENEKLLTQMESEKENLQSKINHL 647
Score = 48.9 bits (115), Expect = 6e-05
Identities = 75/307 (24%), Positives = 127/307 (40%), Gaps = 40/307 (13%)
Query: 61 LRNVVEELEEREMKLQSELLEYYSLKEQVPVIEEFQRQLRIKSVEIDMLHMTIKSLQEEN 120
+ +++E+E+ + KL+ + E LK Q+ + Q QL K +++ H K E
Sbjct: 2599 VNGLIQEVEDGKQKLEKKDEEISRLKNQI----QDQEQLVSKLSQVEGEHQLWKEQNLEL 2654
Query: 121 NKLQEELIHE--------ASAKRELEVARNKIKELQRQIKIIANQTKGQLLLLKQKVSGL 172
L EL + AS + LEV ++ K L+ ++++ TK + +KV+ +
Sbjct: 2655 RNLTVELEQKIQVLQSKNASLQDTLEVLQSSYKNLENELEL----TKMDKMSFVEKVNKM 2710
Query: 173 QAKEEEVVKKDAEIENNLKTVNDFEIEKKLKTVNDLEI---EAVGLKRRNKELQHEKREL 229
AKE E+ ++ E+ + + +K + +L++ E K + KEL E EL
Sbjct: 2711 TAKETELQREMHEMAQKTAELQEELSGEKNRLAGELQLLLEEIKSSKDQLKELTLENSEL 2770
Query: 230 TVKLNAAESRITELSSVTENEMIADAKSETGRLRHANEDLQKQVEGLQMNRFSEVEELVY 289
L+ E E IA+ +LR + + Q L N+ EVE Y
Sbjct: 2771 KKSLDCMHKDQVEKEGKVREE-IAEY-----QLRLHEAEKKHQALLLDTNKQYEVEIQTY 2824
Query: 290 ---LRWVNACLRYELRNYKAPSGKSLARDLNNSFNPKSQ-----EKAKQLMLEYAG---- 337
L CL + + KS +LNNS +Q +K K L+Y
Sbjct: 2825 REKLTSKEECL--SSQKLEIDLLKSSKEELNNSLKATTQILEELKKTKMDNLKYVNQLKK 2882
Query: 338 -SERGHG 343
+ER G
Sbjct: 2883 ENERAQG 2889
Score = 47.8 bits (112), Expect = 1e-04
Identities = 69/306 (22%), Positives = 133/306 (42%), Gaps = 45/306 (14%)
Query: 45 NETEMAKNGSDSEIEWLRNVVEELEEREMKLQSELLEYYSLKEQVPVIEEFQRQLRIKSV 104
NE E+ G + E++ N +EL+ + K + EL+E KE+ V+ + + +L +
Sbjct: 295 NELELRLQGHEKEMKGQVNKFQELQLQLEKAKVELIE----KEK--VLNKCRDELVRTTA 348
Query: 105 EIDMLHMTIKSLQEENNKLQEELIHEASAKRELEVARNKIKELQRQIKIIANQTKGQLLL 164
+ D +L+++ KL E+L + ++ E AR +++ KI + + Q L
Sbjct: 349 QYDQASTKYTALEQKLKKLTEDL---SCQRQNAESARCSLEQ-----KIKEKEKEFQEEL 400
Query: 165 LKQKVSGLQAKEEEVVKKDAEIENNLKTVNDFEIEKKLKTVNDLEIEAVGLKRRNKELQH 224
+Q+ S Q ++E ++ A + L+ + N L+ E L ++L++
Sbjct: 401 SRQQRS-FQTLDQECIQMKARLTQELQQAKNMH--------NVLQAELDKLTSVKQQLEN 451
Query: 225 EKRELTVKLNAAESRITELSSVTENEMIADAKSETGRLRHANEDLQKQVEGLQMNRFSEV 284
E KL AE + S + ENE LR + E+++K+ L+ + +
Sbjct: 452 NLEEFKQKLCRAEQAF-QASQIKENE-----------LRRSMEEMKKENNLLKSHSEQKA 499
Query: 285 EELVY----LRWVNACLRY-----ELRNYKAPSGKSLARDLNNSFNPKSQE-KAKQLMLE 334
E+ + L+ + CL E K S +++ RDL N + ++L L
Sbjct: 500 REVCHLEAELKNIKQCLNQSQNFAEEMKAKNTSQETMLRDLQEKINQQENSLTLEKLKLA 559
Query: 335 YAGSER 340
A E+
Sbjct: 560 VADLEK 565
Score = 42.4 bits (98), Expect = 0.006
Identities = 70/324 (21%), Positives = 129/324 (39%), Gaps = 41/324 (12%)
Query: 61 LRNVVEELEEREMKLQSELL-----------EYYSLKE-------QVPVIEEFQRQLRIK 102
L VE+LE + L +E++ EY SL++ + E+ QR L
Sbjct: 728 LTGQVEDLEHKLQLLSNEIMDKDRCYQDLHAEYESLRDLLKSKDASLVTNEDHQRSLLAF 787
Query: 103 SVEIDMLHMTIKSLQEENNKLQEELIHEASAKRELEVARNKIKELQRQIKIIANQTKGQL 162
+ M H + E+ + E + + E + + LQ ++ + + Q
Sbjct: 788 DQQPAMHHSFANIIGEQGSMPSER----SECRLEADQSPKNSAILQNRVDSLEFSLESQ- 842
Query: 163 LLLKQKVSGLQAKEEEVVKKDAEIENNLKTVNDF------EIEKKL-KTVNDLEIEAVGL 215
KQ S LQ + EE+V+ EIE NL E +++ K D +
Sbjct: 843 ---KQMNSDLQKQCEELVQIKGEIEENLMKAEQMHQSFVAETSQRISKLQEDTSAHQNVV 899
Query: 216 KRRNKELQHEKRELTVKLNAAESRITELSSVTE-NEMIADAKSETGRLRHANEDLQKQVE 274
L+++++EL + + E+ E+ + + N ++ D+ E L +K++
Sbjct: 900 AETLSALENKEKELQLLNDKVETEQAEIQELKKSNHLLEDSLKELQLLSETLSLEKKEMS 959
Query: 275 GLQMNRFSEVEELVY----LRWVNACLRYELRN--YKAPSGKSLARDLNNSFNPKS-QEK 327
+ E+EEL L+ +NA L E N K+ S + + S + S Q K
Sbjct: 960 SIISLNKREIEELTQENGTLKEINASLNQEKMNLIQKSESFANYIDEREKSISELSDQYK 1019
Query: 328 AKQLMLEYAGSERGHGDTDIESNF 351
++L+L E G+ D+ +
Sbjct: 1020 QEKLILLQRCEETGNAYEDLSQKY 1043
Score = 40.8 bits (94), Expect = 0.017
Identities = 76/324 (23%), Positives = 138/324 (42%), Gaps = 79/324 (24%)
Query: 4 IMNLANDFDDEILSEFESLLSEQTDFPLLSEKTDDSKKHGGNETEMAKNGSDSEIEWLRN 63
++++ D D ++ ESLL+E + DSK H M K + E+E
Sbjct: 1882 LLHVIEDRDRKV----ESLLNEMKEL--------DSKLHLQEVQLMTKIEACIELE---K 1926
Query: 64 VVEELEEREMKLQSELLEYYSLKEQVPVIEEFQRQLRIKSVEIDMLHMTIKSLQEE---- 119
+V EL++ L SE LEY+S Q E QR + + D+ KS +E+
Sbjct: 1927 IVGELKKENSDL-SEKLEYFSCDHQ----ELLQRVETSEGLNSDLEMHADKSSREDIGDN 1981
Query: 120 ---------------NNKLQEELIHEASAKRE-------LEVAR-----------NKIKE 146
N+L +AS + E LEV + NK K
Sbjct: 1982 VAKVNDSWKERFLDVENELSRIRSEKASIEHEALYLEADLEVVQTEKLCLEKDNENKQKV 2041
Query: 147 ---LQRQIKIIA---NQTKGQLLLLKQKVSGLQAKEEEVVKKDAEIENN----LKTVNDF 196
L+ ++ ++ NQ +G+L + +K + L E++ +K E+E++ L +
Sbjct: 2042 IVCLEEELSVVTSERNQLRGELDTMSKKTTALDQLSEKMKEKTQELESHQSECLHCIQVA 2101
Query: 197 EIEKKLKT---------VNDLEIEAVGLKRRNKELQHEKRELTVKLNAAESRITELSSVT 247
E E K KT V++L + L+ + + L+ + + L++ E++I +L+
Sbjct: 2102 EAEVKEKTELLQTLSSDVSELLKDKTHLQEKLQSLEKDSQALSLTKCELENQIAQLNK-- 2159
Query: 248 ENEMIADAKSETGRLRHANEDLQK 271
E E++ +SE+ + R + D +K
Sbjct: 2160 EKELLV-KESESLQARLSESDYEK 2182
Score = 38.5 bits (88), Expect = 0.082
Identities = 39/204 (19%), Positives = 93/204 (45%), Gaps = 19/204 (9%)
Query: 51 KNGSDSEIEWLRNVVEELEEREMKLQSELLEYYSLKEQVPVIEEFQRQLRIKSVEIDMLH 110
+N S SE L+ + L+E + K+Q E+ + L+E +++ + + +++E + +
Sbjct: 1118 QNNSKSEAGGLKQEIMTLKEEQNKMQKEVNDL--LQENEQLMKVMKTKHECQNLESEPIR 1175
Query: 111 MTIKSLQEENNKLQEELIHEASAKRELEVARNKIKELQRQIKIIANQTKGQLLLLKQKVS 170
++K + E N+ + +LEV + Q+ + + + L L++
Sbjct: 1176 NSVKERESERNQC------NFKPQMDLEVKEISLDSYNAQLVQLEAMLRNKELKLQE--- 1226
Query: 171 GLQAKEEEVVKKDAE-IENNLKTVNDFEIE-KKLKTVNDLEIEA----VGLKRRNKELQH 224
KE+E ++ + + I +L+T N +++ +++ + D EI+A + Q+
Sbjct: 1227 --SEKEKECLQHELQTIRGDLETSNLQDMQSQEISGLKDCEIDAEEKYISGPHELSTSQN 1284
Query: 225 EKRELTVKLNAAESRITELSSVTE 248
+ L L +++ EL + E
Sbjct: 1285 DNAHLQCSLQTTMNKLNELEKICE 1308
Score = 33.5 bits (75), Expect = 2.7
Identities = 38/211 (18%), Positives = 98/211 (46%), Gaps = 16/211 (7%)
Query: 69 EEREMKLQSELLEYYSLKEQVPVIEEFQRQLRIKSVEIDMLHMTIKSLQEENNKLQEELI 128
+E+ KL+ L E SL E E ++ K + + + + +N L+ E +
Sbjct: 1047 QEKNSKLECLLNECTSLCENRKNELEQLKEAFAKEHQEFLTKLAFAEERNQNLMLELETV 1106
Query: 129 HEASAKRELEVARNKIKELQRQIKIIANQTKGQLLLLKQKVSGLQAKEEEVVKKDAEIEN 188
+A R+++ + Q K A K +++ LK++ + +Q + ++++++ ++
Sbjct: 1107 QQA--------LRSEMTDNQNNSKSEAGGLKQEIMTLKEEQNKMQKEVNDLLQENEQLMK 1158
Query: 189 NLKTVND---FEIEKKLKTVNDLEIEAVGLKRRNKELQHEKRELTVKLNAAESRITELSS 245
+KT ++ E E +V + E E + N + Q + + L++ +++ +L +
Sbjct: 1159 VMKTKHECQNLESEPIRNSVKERESER---NQCNFKPQMDLEVKEISLDSYNAQLVQLEA 1215
Query: 246 VTENE--MIADAKSETGRLRHANEDLQKQVE 274
+ N+ + +++ E L+H + ++ +E
Sbjct: 1216 MLRNKELKLQESEKEKECLQHELQTIRGDLE 1246
>ERC1_HUMAN (Q8IUD2) ERC protein 1 (ELKS protein)
Length = 1116
Score = 59.3 bits (142), Expect = 5e-08
Identities = 78/325 (24%), Positives = 133/325 (40%), Gaps = 62/325 (19%)
Query: 14 EILSEFESLLSEQTDFPLLSEKTDDSKKHGG--NETEMAKNGS----DSEIEWLRNVVEE 67
E+ + LL+ QT L+ + DSK+H E+ AK +E++ LR +EE
Sbjct: 474 ELSRKDTELLALQTKLETLTNQFSDSKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEE 533
Query: 68 LEEREMKLQSELL-----------EYYSLKEQVPV-----------IEEFQRQLRIKSVE 105
E K ++ E + LK+ + V IE Q QLR K +
Sbjct: 534 KETMLNKKTKQIQDMAEEKGTQAGEIHDLKDMLDVKERKVNVLQKKIENLQEQLRDKEKQ 593
Query: 106 IDMLHMTIKSLQEENNKLQEEL--IHEASAKRELEVARNK-------------------- 143
+ L +KSLQ + L + EA A++E + R K
Sbjct: 594 MSSLKERVKSLQADTTNTDTALTTLEEALAEKERTIERLKEQRDRDEREKQEEIDNYKKD 653
Query: 144 IKELQRQIKII---ANQTKGQLLLLKQKVSGLQAK--EEEVVKKDAEIENNLKTVNDFEI 198
+K+L+ ++ ++ ++ + LL LK+ S L + +++ K EI K ++
Sbjct: 654 LKDLKEKVSLLQGDLSEKEASLLDLKEHASSLASSGLKKDSRLKTLEIALEQKKEECLKM 713
Query: 199 EKKLKTVNDLEIEAVGLKRRNKELQHEKRELT------VKLNAAESRITELSSVTENEMI 252
E +LK ++ +EA + +QH +RE+T K A R+ E+ ENE
Sbjct: 714 ESQLKKAHEAALEARASPEMSDRIQHLEREITRYKDESSKAQAEVDRLLEILKEVENEK- 772
Query: 253 ADAKSETGRLRHANEDLQKQVEGLQ 277
D + L +D K+V L+
Sbjct: 773 NDKDKKIAELERQVKDQNKKVANLK 797
Score = 50.4 bits (119), Expect = 2e-05
Identities = 73/290 (25%), Positives = 122/290 (41%), Gaps = 54/290 (18%)
Query: 4 IMNLANDFDDEILSEFESLLSEQTDFPLLSEKTDDSKKHGGNETEMAKNG--SDSEIEWL 61
I N D D L E SLL Q D D K+H + +A +G DS ++ L
Sbjct: 647 IDNYKKDLKD--LKEKVSLL--QGDLSEKEASLLDLKEHASS---LASSGLKKDSRLKTL 699
Query: 62 RNVVEELEEREMKLQSELLEYYSLKEQVPVIEEFQRQLRIKSVEIDMLHMTIKSLQEENN 121
+E+ +E +K++S+L + + + E S I L I ++E++
Sbjct: 700 EIALEQKKEECLKMESQLKKAHEAALEARASPEM-------SDRIQHLEREITRYKDESS 752
Query: 122 KLQEELIHEASAKRELEVARN----KIKELQRQIKIIANQTKGQLLLLKQKVSGLQAKEE 177
K Q E+ +E+E +N KI EL+RQ+K +Q K KV+ L+ KE+
Sbjct: 753 KAQAEVDRLLEILKEVENEKNDKDKKIAELERQVK---DQNK--------KVANLKHKEQ 801
Query: 178 EVVKKDAEIENNLKTVNDFEIEKKLKTVNDLEIEAVGLKRRNKELQHEKRELTVKLNAAE 237
KK A++ E ++ +ND +++LQ R+ ++ E
Sbjct: 802 VEKKKSAQMLE--------EARRREDNLND----------SSQQLQDSLRKKDDRIEELE 843
Query: 238 SRITELSSVTENEMIADAKSETGRLRHANEDLQKQVEGLQMNRFSEVEEL 287
+ E +T + A+ E+ R + +KQVE L M +EL
Sbjct: 844 EALRESVQITAEREMVLAQEESAR-----TNAEKQVEELLMAMEKVKQEL 888
Score = 43.5 bits (101), Expect = 0.003
Identities = 99/532 (18%), Positives = 206/532 (38%), Gaps = 58/532 (10%)
Query: 54 SDSEIEWLRNVVEELEEREMKLQSELLEYYSLKEQVPVIEEFQRQLRIKSVEIDMLHMTI 113
++ + L +++E+ E+ L+ E+ + + Q + +K +I + +
Sbjct: 339 AEMHVHHLESLLEQKEKENSMLREEMHRRFENAPDSAKTKALQTVIEMKDSKISSMERGL 398
Query: 114 KSLQEENNKLQEELIHEASAKRELEVARNKIKELQRQIKIIANQTKGQLLLLKQKVSGLQ 173
+ L+EE L+ + A + E E +++ + K + N+ + LK+++S +
Sbjct: 399 RDLEEEIQMLKS---NGALSTEEREEEMKQMEVYRSHSKFMKNKVEQ----LKEELSSKE 451
Query: 174 AKEEEVVKKDAEIENNLKTVNDFEIEKKLKTVNDLEIEAVGLKRRNKELQHEKRELTVKL 233
A+ EE+ KK A ++ + V E+ +K + L+ + L + + + L L
Sbjct: 452 AQWEELKKKAAGLQAEIGQVKQ-ELSRKDTELLALQTKLETLTNQFSDSKQHIEVLKESL 510
Query: 234 NAAESRITELSSVTENEMIADAKSETGRLRHANEDLQKQVE--GLQMNRFSEVEEL--VY 289
A E R L + + + + ET L + +Q E G Q +++++ V
Sbjct: 511 TAKEQRAAILQTEVDALRLRLEEKET-MLNKKTKQIQDMAEEKGTQAGEIHDLKDMLDVK 569
Query: 290 LRWVNAC------LRYELRNYKAPSGKSLARDLNNSFNPKSQEKAKQLMLEYAGSERGHG 343
R VN L+ +LR+ K SL + + + LE A +E+
Sbjct: 570 ERKVNVLQKKIENLQEQLRD-KEKQMSSLKERVKSLQADTTNTDTALTTLEEALAEKERT 628
Query: 344 DTDIESNFSHDHSSPGSEDLDNAYINSPTYK--YSNLSKKTSLIQ--KLKKWNKNNDSSA 399
++ D E++DN YK +L +K SL+Q +K D
Sbjct: 629 IERLKEQRDRDEREK-QEEIDN-------YKKDLKDLKEKVSLLQGDLSEKEASLLDLKE 680
Query: 400 FSSPARSLSIGSPCRVSTSYRPRNTLESLMLRNAHDAVAITTFEQKEHKPTHSPETPFLP 459
+S S + R+ TLE + + + + + + +K H+
Sbjct: 681 HASSLASSGLKKDSRL-------KTLEIALEQKKEECLKMESQLKKAHE----------- 722
Query: 460 SLRKVSSSDDILDSVSASFQLMSKSVDRSLDEKYPAYKDLHKLALAREKQLKEKAEK--- 516
+ + +S ++ D + Q + + + R DE A ++ +L ++ EK +K
Sbjct: 723 AALEARASPEMSDRI----QHLEREITRYKDESSKAQAEVDRLLEILKEVENEKNDKDKK 778
Query: 517 -ARGEKFGDNSNLNTTKAEEERSTSLDSELTQVNEKACVSDGLNKQSEDVKD 567
A E+ + N + + + E D LN S+ ++D
Sbjct: 779 IAELERQVKDQNKKVANLKHKEQVEKKKSAQMLEEARRREDNLNDSSQQLQD 830
Score = 36.6 bits (83), Expect = 0.31
Identities = 144/765 (18%), Positives = 298/765 (38%), Gaps = 122/765 (15%)
Query: 66 EELEEREMKLQS-----------ELLEYYSL-KEQVPVIEEFQRQLRIKSVEIDMLHMTI 113
+++E +E KL S EL + +L K++ I ++ Q R+ E + MTI
Sbjct: 170 KDVEVKESKLSSSMNSIKTFWSPELKKERALRKDEASKITIWKEQYRVVQEENQHMQMTI 229
Query: 114 KSLQEENNKLQE--ELIHEASAKRELE--VARNKIKELQRQIKIIANQTKGQLLLLKQKV 169
++LQ+E ++ +L + S+ R E VA + QR Q K +L LL++ +
Sbjct: 230 QALQDELRIQRDLNQLFQQDSSSRTGEPCVAELTEENFQRLHAEHERQAK-ELFLLRKTL 288
Query: 170 SGLQAKEEEVVKKDAEIENNLKTVN--DFEIEKKLKTVNDLEIEAVGLKRRNKELQHEKR 227
++ + IE +T+N D I+K L+ +++ GL + E HE+
Sbjct: 289 EEMELR----------IETQKQTLNARDESIKKLLEM-----LQSKGLSAKATEEDHER- 332
Query: 228 ELTVKLNAAESRITELSSVTENEMIADAKSETGRLRHANEDLQKQVEGLQMNRFSEVEEL 287
T +L AE + L S+ E + + E LR E++ ++ E + ++ +
Sbjct: 333 --TRRLAEAEMHVHHLESLLEQK-----EKENSMLR---EEMHRRFENAPDSAKTKALQT 382
Query: 288 VYLRWVNACLRYELRNYKAPSGKSLARDLNNSFNPKSQEKAKQLMLEYAGSERGHGDTDI 347
V E+++ K S + RDL A + ER +
Sbjct: 383 V----------IEMKDSKISSMERGLRDLEEEIQMLKSNGA------LSTEEREEEMKQM 426
Query: 348 ESNFSHDHSSPGSEDLDNAYINSPTYKYSNLSKKTSLIQ------KLKKWNKNNDSSAFS 401
E SH + ++S ++ L KK + +Q K + K+ + A
Sbjct: 427 EVYRSHSKFMKNKVEQLKEELSSKEAQWEELKKKAAGLQAEIGQVKQELSRKDTELLALQ 486
Query: 402 SPARSLSIGSPCRVSTSYRPRNTLESLMLRNAHDAVAITTFEQKEHKPTHSPETPFLPSL 461
+ +L+ + S S + L+ + A + T ET
Sbjct: 487 TKLETLT----NQFSDSKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKETMLNKKT 542
Query: 462 RKVSSSDDILDSVSASFQLMSKSVD---RSLDEKYPAYKDLHKLALAREKQ---LKEKAE 515
+++ + + + + +D R ++ ++L + +EKQ LKE+ +
Sbjct: 543 KQIQDMAEEKGTQAGEIHDLKDMLDVKERKVNVLQKKIENLQEQLRDKEKQMSSLKERVK 602
Query: 516 KARGEKFGDNSNLNTTK---AEEERSTSLDSELTQVNEKACVSDGLNKQSEDVKDFDNQT 572
+ + ++ L T + AE+ER+ E +E+ + ++ +D+KD +
Sbjct: 603 SLQADTTNTDTALTTLEEALAEKERTIERLKEQRDRDERE-KQEEIDNYKKDLKDL-KEK 660
Query: 573 ITEMKLFKIEKRPPRLPRPPPKPSDGAPVSNSLNEIPYAPSVPSPPPPPGSLPRGAVGDD 632
++ ++ EK ++ L+ +A S+ S G D
Sbjct: 661 VSLLQGDLSEKE-----------------ASLLDLKEHASSLAS---------SGLKKDS 694
Query: 633 KVKRAP-ELVEFYQSLMKREAKKDASLLTSSTSNAADTRSNVIAEIENRSSFLLAVKADV 691
++K L + + +K E++ + + + A+ S+ I +E + +
Sbjct: 695 RLKTLEIALEQKKEECLKMESQLKKAHEAALEARASPEMSDRIQHLEREITRYKDESSKA 754
Query: 692 ETQGDFVMSLATEVRAASFSKIEDVVAFVNWLDEELSFLSDERAVLKHFDWPEGKSDALR 751
+ + D ++ + EV K + + L+ ++ + + A LKH + E K A
Sbjct: 755 QAEVDRLLEILKEVENEKNDKDKKIAE----LERQVKDQNKKVANLKHKEQVEKKKSA-- 808
Query: 752 EASFEYQDLMKLEKQVSNFTDDPKLPCEDALQKMYSLLEKLEQSV 796
Q L + ++ N D + +D+L+K +E+LE+++
Sbjct: 809 ------QMLEEARRREDNLNDSSQ-QLQDSLRKKDDRIEELEEAL 846
Score = 35.4 bits (80), Expect = 0.70
Identities = 46/221 (20%), Positives = 93/221 (41%), Gaps = 23/221 (10%)
Query: 46 ETEMAKNGSDSEIEWLRNVVEELEEREMKLQSELLEYYSLKEQVPVIEEFQRQLRIKSVE 105
E E KN D +I L V++ ++ L+ + E K+ ++EE +R+
Sbjct: 767 EVENEKNDKDKKIAELERQVKDQNKKVANLKHK--EQVEKKKSAQMLEEARRRE------ 818
Query: 106 IDMLHMTIKSLQEENNKLQEELIHEASAKRELEVARNKIKELQRQIKIIANQTKGQLLLL 165
+L + + +LQ+ L + ELE A + ++ + +++ Q +
Sbjct: 819 --------DNLNDSSQQLQDSLRKKDDRIEELEEALRESVQITAEREMVLAQEESARTNA 870
Query: 166 KQKVSGLQAKEEEVVKKDAEIENNLKTVNDFEIEKKLKTVNDLEIEAVGLKRRNKELQHE 225
+++V L E+V ++ ++ L + EK+ N + A K + L+ +
Sbjct: 871 EKQVEELLMAMEKVKQELESMKAKLSSTQQSLAEKETHLTN---LRAERRKHLEEVLEMK 927
Query: 226 KRELTVKLNAAESRIT--ELSSVTE--NEMIADAKSETGRL 262
+ L ++ ++ I ELSS + E +A K E RL
Sbjct: 928 QEALLAAISEKDANIALLELSSSKKKTQEEVAALKREKDRL 968
>RA50_AQUAE (O67124) Probable DNA double-strand break repair rad50
ATPase
Length = 978
Score = 58.9 bits (141), Expect = 6e-08
Identities = 109/533 (20%), Positives = 216/533 (40%), Gaps = 70/533 (13%)
Query: 57 EIEWLRNVVEE-LEEREMKLQSELLEYYSLKEQVPVIEEFQRQLRIKSVEIDMLHMTIKS 115
E+E +R + E + E K ++ EY LK+ P +E +L T+K+
Sbjct: 165 ELEKVRQLASETFKNLEGKREALKKEYELLKDYTPTKKE-------------VLEKTLKN 211
Query: 116 LQEENNKLQEELIHEASAKRELEVARNKIKELQRQIKIIANQTKGQLLLLKQKVSGLQAK 175
L+EE +L+E E ++EL+ A K L+R++ + K+ L+
Sbjct: 212 LEEELKELKET---EEKLRQELKKAEEK-DSLERELSQVVT-----------KLKELENL 256
Query: 176 EEEVVKKDAEIENNLKTVNDFEIEKKLKTVNDLEIEAVGLKRRNKELQHEKRELTVKLNA 235
E+EV K ++E + K I K+ + +++ + LK R +L E L +L+
Sbjct: 257 EKEVEKLREKLEFSRKVAPYVPIAKR---IEEIDKKLTELKVRKNKLTKELAVLKDELSF 313
Query: 236 AESRITELSSVTENEMIADAKSETGRLRHANEDLQKQVEGL-QMNRFSEVEELVYLRWVN 294
A+ + + + E E + K L H + LQ+ E L ++++ S + +
Sbjct: 314 AQEELNRIEA--EKEKFKEEKEREKELEHRLKKLQEIKEILKELSQLSSSLKEKEREYEQ 371
Query: 295 ACLRYELRNYKAPSGKSLARDLNNSFNPKSQEKAKQLMLEYAGSERGHGD---TDIESNF 351
A +E + + GK L + EK K+L E + + +++
Sbjct: 372 AKQEFEDLSERVEKGKKLVAETEEKL-----EKIKELFSEEEYTSLKMKERLLVELQRKL 426
Query: 352 SHDHSSPGS-EDLDNAYINSPTYKYSNLSKKTSLIQKLKKWNKNNDSSAFSSPARSLSIG 410
G E+L Y L++ L ++LK+ + + +S LS G
Sbjct: 427 KELKEKEGQLENLTQKYKEKKKVHEKVLNELKELERELKERELHYHAHMVAS---YLSPG 483
Query: 411 SPCRVSTSYRPRNTLESLMLRNAHDAVAITTFEQKEHKPTHSPETPFLPSLRKVSSSDDI 470
C V LE++ + ++KE + +T +K++S +
Sbjct: 484 DTCPVCGGIYRGKALENVDAEGISELKHAKELKEKEEREI---DTTLKLYAQKINSLKEE 540
Query: 471 LDSVSASFQLMSKSVDRSLDEKYPAYKDLHKLALAREKQLKEKAEKARGEKFGDNSNLNT 530
++ + + + K + +L E+ K L +L + +EK L+ K K R + +
Sbjct: 541 MEKLRNEVEELRKEIPENLKER---IKKLEELRIEKEK-LEHKLNKYR------KALEDR 590
Query: 531 TKAEEERSTSLDSELTQVNEKACVSDGLNKQSEDVKDFDNQTITEMKLFKIEK 583
K +EE L T++ + + + ++S VK+F +L+++E+
Sbjct: 591 QKQKEEAQAKLHKAQTELE---LLKEKIREKSRLVKEF-------KELYRVER 633
Score = 58.5 bits (140), Expect = 8e-08
Identities = 56/259 (21%), Positives = 118/259 (44%), Gaps = 49/259 (18%)
Query: 52 NGSDSEIEWLRNVVEELEER-------------EMKLQSELLEYY------SLKEQVPVI 92
N E+E LRN VEEL + E++++ E LE+ +L+++
Sbjct: 535 NSLKEEMEKLRNEVEELRKEIPENLKERIKKLEELRIEKEKLEHKLNKYRKALEDRQKQK 594
Query: 93 EEFQRQLRIKSVEIDMLHMTIKS----------------LQEENNKLQEELIHEASAKRE 136
EE Q +L E+++L I+ L++ L+EE+ + S +E
Sbjct: 595 EEAQAKLHKAQTELELLKEKIREKSRLVKEFKELYRVERLEDYEESLKEEINYINSKLQE 654
Query: 137 LEVARNKIKELQRQIKIIANQTKGQLLLLKQKVSGLQAKEEEVVKKDAEIENNLKTVNDF 196
+E K+++ ++ ++ +G+L L + ++ L+ + +E +K+ A I +
Sbjct: 655 IEEKEKKLRKHFEELSSRKSKLEGELSALNESINSLEEERKEKLKELANI---------Y 705
Query: 197 EIEKKLKTVNDLEI--EAVGLKRRNKELQHEKRELTVKLNAAESRITELSSVTENEMIAD 254
E+ K + V +L + + L+R+ KE + + L +K + E ++ E + E ++D
Sbjct: 706 EVAKSPREVVELYLGDKEAELERKIKEFEESFQSLKLKKSEIEEKLKEYEGIRE---LSD 762
Query: 255 AKSETGRLRHANEDLQKQV 273
K E ++ E+ K++
Sbjct: 763 IKGEYESVKTQLEEKHKKL 781
Score = 52.8 bits (125), Expect = 4e-06
Identities = 57/204 (27%), Positives = 99/204 (47%), Gaps = 17/204 (8%)
Query: 51 KNGSDSEIEWLRNVVEELE--EREMKLQSELLEYY-SLKEQVPV---IEEFQRQLRIKSV 104
K+ + E+ + ++ELE E+E++ E LE+ + VP+ IEE ++L V
Sbjct: 236 KDSLERELSQVVTKLKELENLEKEVEKLREKLEFSRKVAPYVPIAKRIEEIDKKLTELKV 295
Query: 105 EIDMLHMTIKSLQEENNKLQEELIHEASAKRELEVARNKIKELQRQIKIIANQTKGQLLL 164
+ L + L++E + QEEL + K + + + + KEL+ ++K + + K L
Sbjct: 296 RKNKLTKELAVLKDELSFAQEELNRIEAEKEKFKEEKEREKELEHRLKKL-QEIKEILKE 354
Query: 165 LKQKVSGLQAKEEEVVKKDAEIENNLKTVND-----FEIEKKLKTVNDL--EIEAVGLKR 217
L Q S L+ KE E + E E+ + V E E+KL+ + +L E E LK
Sbjct: 355 LSQLSSSLKEKEREYEQAKQEFEDLSERVEKGKKLVAETEEKLEKIKELFSEEEYTSLKM 414
Query: 218 RNK---ELQHEKRELTVKLNAAES 238
+ + ELQ + +EL K E+
Sbjct: 415 KERLLVELQRKLKELKEKEGQLEN 438
Score = 48.1 bits (113), Expect = 1e-04
Identities = 114/462 (24%), Positives = 178/462 (37%), Gaps = 113/462 (24%)
Query: 16 LSEFESLLSEQTDFPLLSEKTDDSKKHGGNETEMAKNGSDS---EIEWLRNVVEELEERE 72
L E + +L E + S K E E AK + +E + +V E EE+
Sbjct: 345 LQEIKEILKELSQL-------SSSLKEKEREYEQAKQEFEDLSERVEKGKKLVAETEEKL 397
Query: 73 MKLQSELL---EYYSLKEQVPVIEEFQRQLRIKSVEIDMLHMTIKSLQEENNKLQEELIH 129
K++ EL EY SLK + ++ E QR+L K L+E+ +L+
Sbjct: 398 EKIK-ELFSEEEYTSLKMKERLLVELQRKL--------------KELKEKEGQLENLTQK 442
Query: 130 EASAKRELEVARNKIKELQRQIK----------------------IIANQTKGQLL--LL 165
K+ E N++KEL+R++K + +G+ L +
Sbjct: 443 YKEKKKVHEKVLNELKELERELKERELHYHAHMVASYLSPGDTCPVCGGIYRGKALENVD 502
Query: 166 KQKVSGLQAKEEEVVKKDAEIENNLK----TVNDF--EIEKKLKTVNDLEIE-AVGLKRR 218
+ +S L+ +E K++ EI+ LK +N E+EK V +L E LK R
Sbjct: 503 AEGISELKHAKELKEKEEREIDTTLKLYAQKINSLKEEMEKLRNEVEELRKEIPENLKER 562
Query: 219 NK---ELQHEKRELTVKLN----AAESRITELSSV--------TENEMIADAKSETGRLR 263
K EL+ EK +L KLN A E R + TE E++ + E RL
Sbjct: 563 IKKLEELRIEKEKLEHKLNKYRKALEDRQKQKEEAQAKLHKAQTELELLKEKIREKSRLV 622
Query: 264 HANEDLQKQVEGLQMNRFSEVEELVYLRWVNACLR---------------YELRNYKAPS 308
++L + VE L+ S EE+ Y +N+ L+ R K
Sbjct: 623 KEFKELYR-VERLEDYEESLKEEINY---INSKLQEIEEKEKKLRKHFEELSSRKSKLEG 678
Query: 309 GKSLARDLNNSFNPKSQEKAKQL--MLEYAGSER-------GHGDTDIESNFSHDHSSPG 359
S + NS + +EK K+L + E A S R G + ++E S
Sbjct: 679 ELSALNESINSLEEERKEKLKELANIYEVAKSPREVVELYLGDKEAELERKIKEFEESFQ 738
Query: 360 SEDLDNAYINSPTYKYSNL-----------SKKTSLIQKLKK 390
S L + I +Y + S KT L +K KK
Sbjct: 739 SLKLKKSEIEEKLKEYEGIRELSDIKGEYESVKTQLEEKHKK 780
>MYHD_HUMAN (Q9UKX3) Myosin heavy chain, skeletal muscle, extraocular
(MyHC-eo)
Length = 1938
Score = 58.9 bits (141), Expect = 6e-08
Identities = 114/583 (19%), Positives = 232/583 (39%), Gaps = 82/583 (14%)
Query: 10 DFDDEILSEFESLLSEQTDFPLLSEKTDDSKKHGGNETEMAKNGSDSEIEWLRNVVEELE 69
D ++E E L ++ + L + DD + H +I+ L+ +EELE
Sbjct: 1072 DLENEKQQIEEKLKKKEFELSQLQARIDDEQVHSLQ--------FQKKIKELQARIEELE 1123
Query: 70 ER---EMKLQSELLEYYS--LKEQVPVIEEFQRQLRIKSVEIDMLHMTIKSLQEENNKLQ 124
E E L++++ + S +E + E + S +I+M Q+ L+
Sbjct: 1124 EEIEAEHTLRAKIEKQRSDLARELEEISERLEEASGATSAQIEMNKKREAEFQKMRRDLE 1183
Query: 125 EELI-HEASAKRELEVARNKIKELQRQI---KIIANQTKGQLLLLKQKVSGLQAKEEEVV 180
E + HEA+A + + + EL QI + + + + + LK ++ + + E +
Sbjct: 1184 EATLQHEATAATLRKKQADSVAELGEQIDNLQRVKQKLEKEKSELKMEIDDMASNIEALS 1243
Query: 181 KKDAEIENNLKTVNDFEIEKKLKT------VNDLEIEAVGLKRRNKELQH---EKRELTV 231
K + IE +TV D E K K ++DL ++ L+ +N EL H EK L
Sbjct: 1244 KSKSNIERTCRTVEDQFSEIKAKDEQQTQLIHDLNMQKARLQTQNGELSHRVEEKESLIS 1303
Query: 232 KLNAAESRITELSSVTENEMIADAKSETGRLRHANEDLQKQVEGLQMNRFSEVEELVYLR 291
+L ++ +T+ + +M + K++ + HA + + + L+ E E L+
Sbjct: 1304 QLTKSKQALTQQLEELKRQMEEETKAKNA-MAHALQSSRHDCDLLREQYEEEQEAKAELQ 1362
Query: 292 WVNACLRYELRNYKA--------------PSGKSLARDLNNSFNPKSQEKAKQLMLEYAG 337
+ E+ +K + K LA+ L + +K LE
Sbjct: 1363 RALSKANSEVAQWKTKYETDAIQRTEELEEAKKKLAQRLQEAEEKTETANSKCASLEKT- 1421
Query: 338 SERGHGDT-DIESNFSHDHSSPGSEDLDNAYINSPTYKYSNLSKKTSLIQKLKKWNKNND 396
+R G+ D+ + H++ + D K+ + + L +W + D
Sbjct: 1422 KQRLQGEVEDLMRDLERSHTACATLD----------------KKQRNFDKVLAEWKQKLD 1465
Query: 397 SS-----AFSSPARSLSIGSPCRVSTSYRPRNTLESLMLRNAHDAVAITTFEQKEHKPTH 451
S A +RSLS + ++ RN E ++ D + E K +
Sbjct: 1466 ESQAELEAAQKESRSLS-------TELFKMRNAYEEVV-----DQLETLRRENKNLQEEI 1513
Query: 452 SPETPFL----PSLRKVSSSDDILDSVSASFQLMSKSVDRSLDEKYPAYKDLHKLALARE 507
S T + +L++ + +++ + Q+ + V+ SL+ + + +L L++
Sbjct: 1514 SDLTEQIAETGKNLQEAEKTKKLVEQEKSDLQVALEEVEGSLEHEESKILRV-QLELSQV 1572
Query: 508 KQLKEKAEKARGEKFGDNSNLNTTKAEEERSTSLDSELTQVNE 550
K ++ + E+ + N+ +A E + LD+E+ N+
Sbjct: 1573 KSELDRKVIEKDEEI-EQLKRNSQRAAEALQSVLDAEIRSRND 1614
Score = 53.9 bits (128), Expect = 2e-06
Identities = 75/363 (20%), Positives = 161/363 (43%), Gaps = 41/363 (11%)
Query: 1 MGSIMNLANDFDDEILSEFESLLSEQTDFP-------LLSEKTDDSKKHGGNETEM---- 49
M S++ ND ++ SE E+L+ + LL K + + E EM
Sbjct: 881 MVSLLQEKNDLQLQVQSETENLMDAEERCEGLIKSKILLEAKVKELTERLEEEEEMNSEL 940
Query: 50 --AKNGSDSEIEWLRNVVEELEEREMKLQSELL----EYYSLKEQVPVIEEFQRQLRIKS 103
K + + L+ +++LE K++ E + +L E++ +EE +L +
Sbjct: 941 VAKKRNLEDKCSSLKRDIDDLELTLTKVEKEKHATENKVKNLSEEMTALEENISKLTKEK 1000
Query: 104 VEIDMLHM-TIKSLQEENNKLQEELIHEASAKRE---LEVARNKIKELQRQIKIIANQTK 159
+ H T+ LQ E +K+ + A +++ LE + + K+L+ ++ + +
Sbjct: 1001 KSLQEAHQQTLDDLQVEEDKVNGLIKINAKLEQQTDDLEGSLEQEKKLRADLERAKRKLE 1060
Query: 160 GQLLLLKQKVSGLQAKEEEVVKKDAEIENNLKTVNDFEIEKKLKTVNDLEIEAVGLKRRN 219
G L + ++ + L+ ++++ IE LK +FE+ + ++D ++ ++ +++
Sbjct: 1061 GDLKMSQESIMDLENEKQQ-------IEEKLKK-KEFELSQLQARIDDEQVHSLQFQKKI 1112
Query: 220 KELQHEKRELTVKLNAAESRITELSSVTENEMIADAKSETGRLRHANEDLQKQVEGLQMN 279
KELQ EL ++ A + ++ +++ + + + RL A+ Q+E MN
Sbjct: 1113 KELQARIEELEEEIEAEHTLRAKIEK-QRSDLARELEEISERLEEASGATSAQIE---MN 1168
Query: 280 RFSEVEELVYLRWV-NACLRYE-----LRNYKAPSGKSLARDLNN--SFNPKSQEKAKQL 331
+ E E R + A L++E LR +A S L ++N K +++ +L
Sbjct: 1169 KKREAEFQKMRRDLEEATLQHEATAATLRKKQADSVAELGEQIDNLQRVKQKLEKEKSEL 1228
Query: 332 MLE 334
+E
Sbjct: 1229 KME 1231
Score = 45.4 bits (106), Expect = 7e-04
Identities = 59/279 (21%), Positives = 128/279 (45%), Gaps = 40/279 (14%)
Query: 45 NETEMAKNGSDSEI----EWLRNVVEELEEREMKLQSELLEYYSLKEQVPVIEEFQRQLR 100
NE E+ S+ ++ LR V +L++ ++ L L LKEQ+ ++E R+
Sbjct: 1627 NEMEIQLGHSNRQMAETQRHLRTVQGQLKDSQLHLDDALRSNEDLKEQLAIVE---RRNG 1683
Query: 101 IKSVEIDMLHMTIKSLQEENNKLQEELIHEASAKRELEVARNKIKELQRQIKIIANQTKG 160
+ E++ + + ++ + ++EL+ A ++++ L Q + N K
Sbjct: 1684 LLLEELEEMKVALEQTERTRRLSEQELLD----------ASDRVQLLHSQNTSLINTKK- 1732
Query: 161 QLLLLKQKVSGLQAKEEEVVKKDAEIENNL-KTVNDF-----EIEKKLKTVNDLEIEAVG 214
L+ ++ QA+ E +++ E K + D E++K+ T LE
Sbjct: 1733 ---KLEADIAQCQAEVENSIQESRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKN 1789
Query: 215 LKRRNKELQH---EKRELTVK-----LNAAESRITELSSVTENEMIADAKSETGRLRHAN 266
L++ K+LQH E +L +K + E+R+ EL ENE+ + K L+ A+
Sbjct: 1790 LEQTVKDLQHRLDEAEQLALKGGKKQIQKLENRVREL----ENELDVEQKRGAEALKGAH 1845
Query: 267 EDLQKQVEGLQMNRFSEVEELVYLRWVNACLRYELRNYK 305
+ +++V+ + + + ++ L+ + L+ ++++YK
Sbjct: 1846 K-YERKVKEMTYQAEEDRKNILRLQDLVDKLQAKVKSYK 1883
Score = 40.4 bits (93), Expect = 0.022
Identities = 38/190 (20%), Positives = 89/190 (46%), Gaps = 17/190 (8%)
Query: 61 LRNVVEELEEREMKLQSELLEYYSLKEQVPVIEEFQRQL-RIKSVEIDMLHMTIKSLQEE 119
+ N ++E E K + + + + E++ ++ L R+K L T+K LQ
Sbjct: 1745 VENSIQESRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKK----NLEQTVKDLQHR 1800
Query: 120 NNKLQEELIHEASAKRELEVARNKIKELQRQIKIIANQTKGQLLLLKQKVSGLQAKEEEV 179
++ ++ + K++++ N+++EL+ ++ + Q +G L + + K +E+
Sbjct: 1801 LDEAEQLALK--GGKKQIQKLENRVRELENELDV--EQKRGAEAL--KGAHKYERKVKEM 1854
Query: 180 VKKDAEIENNLKTVNDF--EIEKKLKT----VNDLEIEAVGLKRRNKELQHEKRELTVKL 233
+ E N+ + D +++ K+K+ + E +A R + +QHE E +
Sbjct: 1855 TYQAEEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQANTQLSRCRRVQHELEEAAERA 1914
Query: 234 NAAESRITEL 243
+ AES++ +L
Sbjct: 1915 DIAESQVNKL 1924
Score = 38.9 bits (89), Expect = 0.063
Identities = 33/173 (19%), Positives = 84/173 (48%), Gaps = 20/173 (11%)
Query: 101 IKSVEIDMLHMTIKSLQEENNKLQEELIHEASAKRELEVARNKIKELQRQIKI-IANQTK 159
+KS E + T+K E+ + +EEL + ++ELE + + + +++ + ++T+
Sbjct: 844 LKSAEAEKEMATMK---EDFERTKEELARSEARRKELEEKMVSLLQEKNDLQLQVQSETE 900
Query: 160 GQL-------------LLLKQKVSGLQAKEEEVVKKDAEIENNLKTVNDFEIEKKLKTVN 206
+ +LL+ KV L + EE + ++E+ + + D + + ++
Sbjct: 901 NLMDAEERCEGLIKSKILLEAKVKELTERLEEEEEMNSELVAKKRNLED-KCSSLKRDID 959
Query: 207 DLEIEAVGLKRRNKELQHEKRELTVKLNAAESRITELSSVTENEMIADAKSET 259
DLE+ +++ +++ + L+ ++ A E I++L+ E + + +A +T
Sbjct: 960 DLELTLTKVEKEKHATENKVKNLSEEMTALEENISKLTK--EKKSLQEAHQQT 1010
Database: sprot
Posted date: Nov 25, 2004 10:54 AM
Number of letters in database: 59,974,054
Number of sequences in database: 164,201
Lambda K H
0.310 0.128 0.345
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 104,170,729
Number of Sequences: 164201
Number of extensions: 4728351
Number of successful extensions: 29961
Number of sequences better than 10.0: 1307
Number of HSP's better than 10.0 without gapping: 141
Number of HSP's successfully gapped in prelim test: 1203
Number of HSP's that attempted gapping in prelim test: 23389
Number of HSP's gapped (non-prelim): 4967
length of query: 915
length of database: 59,974,054
effective HSP length: 119
effective length of query: 796
effective length of database: 40,434,135
effective search space: 32185571460
effective search space used: 32185571460
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 71 (32.0 bits)
Medicago: description of AC146570.7