BLASTP 2.2.2 [Dec-14-2001]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= AC146567.11 - phase: 0 
         (331 letters)

Database: sprot 
           164,201 sequences; 59,974,054 total letters

Searching..................................................done

                                                                   Score     E
Sequences producing significant alignments:                        (bits)  Value

CH02_HUMAN (O94905) Protein C8orf2 (UNQ2441/PRO9924/PRO5003)          348  1e-95
TPM_ECHMU (Q95PU1) Tropomyosin                                         45  3e-04
YLX8_CAEEL (P46504) Hypothetical protein F23F12.8 in chromosome ...    42  0.002
TPM_DERPT (O18416) Tropomyosin (Allergen Der p 10)                     42  0.002
TPM_DERFA (Q23939) Tropomyosin (Allergen Der f 10) (Mag44)             42  0.002
M4K4_MOUSE (P97820) Mitogen-activated protein kinase kinase kina...    40  0.011
HFLC_HAEIN (P44545) HflC protein (EC 3.4.-.-)                          40  0.011
TPM_LEPDS (Q9NFZ4) Tropomyosin (Allergen Lep d 10)                     39  0.014
M4K4_HUMAN (O95819) Mitogen-activated protein kinase kinase kina...    39  0.014
KI21_STRPU (P46871) Kinesin-II 95 kDa subunit (KRP-85/95 95 kDa ...    39  0.018
DNAK_VIBCH (O34241) Chaperone protein dnaK (Heat shock protein 7...    38  0.031
YAFA_SCHPO (Q09863) Hypothetical protein C29E6.10c in chromosome I     38  0.040
TPM_SCHHA (Q26503) Tropomyosin                                         38  0.040
TPM_CHAFE (Q9N2R3) Tropomyosin (Allergen Cha f 1) (Cha f I) (Fra...    38  0.040
TPM1_CAEEL (Q22866) Tropomyosin isoforms 1/2                           38  0.040
MYO6_MOUSE (Q64331) Myosin VI                                          38  0.040
MYO6_HUMAN (Q9UM54) Myosin VI                                          38  0.040
INCE_HUMAN (Q9NQS7) Inner centromere protein                           38  0.040
YI73_AQUAE (O67720) Hypothetical protein AQ_1873                       37  0.052
TPM_METEN (Q25456) Tropomyosin (Allergen Met e 1) (Met e I)            37  0.052

>CH02_HUMAN (O94905) Protein C8orf2 (UNQ2441/PRO9924/PRO5003)
          Length = 339

 Score =  348 bits (892), Expect = 1e-95
 Identities = 174/304 (57%), Positives = 231/304 (75%), Gaps = 1/304 (0%)

Query: 5   LQVLVPSASPSF-KNTMAIVHQVPEGHVGVYWRGGALLKTITEPGFHMKMPFLTQFEPVQ 63
           L  +V  AS  F  +  + VH++ EGH+GVY+RGGALL + + PGFH+ +PF+T ++ VQ
Sbjct: 4   LGAVVAVASSFFCASLFSAVHKIEEGHIGVYYRGGALLTSTSGPGFHLMLPFITSYKSVQ 63

Query: 64  VTLQTDEVTDIPCGTKGGVMIVFGKIEVVNRLHKESVYETLLNYGVQYDKTWIYDKIHHE 123
            TLQTDEV ++PCGT GGVMI F +IEVVN L   +VY+ + NY   YDK  I++KIHHE
Sbjct: 64  TTLQTDEVKNVPCGTSGGVMIYFDRIEVVNFLVPNAVYDIVKNYTADYDKALIFNKIHHE 123

Query: 124 INQFCSSHSLQQVYIDVFDQIDEKMKDALQVDCTRYAPGIEIIGVRVTKPNIPESIRHNF 183
           +NQFCS H+LQ+VYI++FDQIDE +K ALQ D T  APG+ I  VRVTKPNIPE+IR N+
Sbjct: 124 LNQFCSVHTLQEVYIELFDQIDENLKLALQQDLTSMAPGLVIQAVRVTKPNIPEAIRRNY 183

Query: 184 EQMEEERTKVLIAIEKQKVSEKEAETMKKMAISEAEKNANVSKILMEQKLSEKDSARRQE 243
           E ME E+TK+LIA +KQKV EKEAET +K A+ EAEK A V++I   QK+ EK++ ++  
Sbjct: 184 ELMESEKTKLLIAAQKQKVVEKEAETERKKALIEAEKVAQVAEITYGQKVMEKETEKKIS 243

Query: 244 EIENAMYLAREKSLADADFYRVIKEAEANRLKLTPEFLELKFIESIANNTKIFFGDKIPN 303
           EIE+A +LAREK+ ADA+ Y  +K AEAN+LKLTPE+L+L   ++IA+N+KI+FG  IPN
Sbjct: 244 EIEDAAFLAREKAKADAECYTAMKIAEANKLKLTPEYLQLMKYKAIASNSKIYFGKDIPN 303

Query: 304 MILD 307
           M +D
Sbjct: 304 MFMD 307


>TPM_ECHMU (Q95PU1) Tropomyosin
          Length = 284

 Score = 45.1 bits (105), Expect = 3e-04
 Identities = 46/206 (22%), Positives = 92/206 (44%), Gaps = 17/206 (8%)

Query: 94  RLHKESVYETLLNYGVQY-DKTWIYDKIHHEINQFCSSHSLQQVYIDVFDQIDEKMKDAL 152
           +L KE+  E  +N   Q  +K   ++K   E+N + S     Q  +D    + E +++A+
Sbjct: 12  KLEKENALEKAINLENQLKEKAKDFEKKEEEMNDWLSKVKNIQTEVDT---VQESLQEAI 68

Query: 153 QV--DCTRYAPGIEIIGVRVTKPN--IPESIRHNFEQMEEERTKVLIAIEKQKVSEKEAE 208
               +  + A   E     +T+    + E    +  ++ E  TK+  A +  + SE+  +
Sbjct: 69  SKLEETEKRATNAEAEVAAMTRRIRLLEEDFEQSSGRLTETSTKLDDASKAAEESERNRK 128

Query: 209 TMKKMAISEAEKNANVSKILMEQKLSEKDSARRQEEIENAMYLAREKSLADADFYRVIKE 268
           T++  +IS+ E+ A + + + E K   +D+ R+ +E       AR  ++ + D  R    
Sbjct: 129 TLETRSISDDERMAQLEEQVKEAKYIAEDAERKYDE------AARRLAVTEVDLERAESR 182

Query: 269 AEANRLKLTPEFLELKFIESIANNTK 294
            E +  K+     EL+    + NN K
Sbjct: 183 LETSESKIVELEEELRI---VGNNMK 205


>YLX8_CAEEL (P46504) Hypothetical protein F23F12.8 in chromosome III
           precursor
          Length = 887

 Score = 42.4 bits (98), Expect = 0.002
 Identities = 37/145 (25%), Positives = 74/145 (50%), Gaps = 11/145 (7%)

Query: 134 QQVYIDVFDQIDEKMKDALQVDCTRYAPGIEIIGVRVTKPNIPESIRHNFE---QMEEER 190
           Q+V ++   Q +E  ++ L+V     A  +E    RV +  +    +H  E   Q EE++
Sbjct: 442 QKVEMEQIRQQEEARQEQLRVLEEERARELE----RVRQEELER--QHQMEILRQQEEDQ 495

Query: 191 TKVLIAIEKQKVSEKEAETMKKMAISEAEKNANVSKILMEQKLSEKDSARRQEEIENAMY 250
            K  +  ++++  ++EAE + +M I E E   N  K++ E+K   K   +  E+ +NA+Y
Sbjct: 496 KKKKLEKDREQREQQEAEELNRMII-EKEMKENKQKMI-EEKNKRKMLEKEMEDRQNAIY 553

Query: 251 LAREKSLADADFYRVIKEAEANRLK 275
              E+ +A+ +  + I+  E  R++
Sbjct: 554 EEEERRIAEEERRKQIEIEERRRIQ 578



 Score = 35.8 bits (81), Expect = 0.15
 Identities = 26/98 (26%), Positives = 47/98 (47%), Gaps = 10/98 (10%)

Query: 184 EQMEEERTKVLIAIEKQKVSEKEAETMKKMAISEAEKNANVSKILMEQKLSEKDSARRQE 243
           ++M+E + K++    K+K+ EKE E  +     E E+     +I  E++  + +   R+ 
Sbjct: 522 KEMKENKQKMIEEKNKRKMLEKEMEDRQNAIYEEEER-----RIAEEERRKQIEIEERRR 576

Query: 244 EIENAMYLAREKSLADA-----DFYRVIKEAEANRLKL 276
             +  M    E+S  DA     +  R IKE+E  R +L
Sbjct: 577 IQQQIMIATEERSRLDAMEREREMLRQIKESEKQRKEL 614



 Score = 30.4 bits (67), Expect = 6.4
 Identities = 29/118 (24%), Positives = 50/118 (41%), Gaps = 29/118 (24%)

Query: 180 RHNFEQMEEERTKVLIAIEKQKVSEKEAETMKKMAISEA--------------------- 218
           +  FE+ME+ER +     ++++   +E E  +K+  SE                      
Sbjct: 314 QEKFEKMEQERLR-----QEKEEKARELERRRKLEESETARQAELDRQATIYAEQERMAM 368

Query: 219 EKNANVSKILMEQKLSEKDSARRQE---EIENAMYLAREKSLADADFYRVIKEAEANR 273
           E+N  + +I +E+K  E +  R++E   EI     L R +        RV +E EA R
Sbjct: 369 ERNRELERIRLEEKKRENERVRQEEIAMEISKIRELERLQLERQRKNERVRQELEAAR 426


>TPM_DERPT (O18416) Tropomyosin (Allergen Der p 10)
          Length = 284

 Score = 42.4 bits (98), Expect = 0.002
 Identities = 32/115 (27%), Positives = 58/115 (49%), Gaps = 14/115 (12%)

Query: 185 QMEEERTKVLIA-IEKQKVSEKEAETMKKM----AISEAEKNANVSKILMEQKLSEKDSA 239
           +  EER K+  A +E+   S  E+E M+KM    +I++ E+   +   L E ++  +D+ 
Sbjct: 100 ERSEERLKIATAKLEEASQSADESERMRKMLEHRSITDEERMEGLENQLKEARMMAEDAD 159

Query: 240 RRQEEIENAMYLAREKSLADADFYRVIKEAEANRLKLTPEFLELKFIESIANNTK 294
           R+ +E+      AR+ ++ +AD  R  + AE    K+     EL+    + NN K
Sbjct: 160 RKYDEV------ARKLAMVEADLERAEERAETGESKIVELEEELRV---VGNNLK 205


>TPM_DERFA (Q23939) Tropomyosin (Allergen Der f 10) (Mag44)
          Length = 284

 Score = 42.0 bits (97), Expect = 0.002
 Identities = 32/115 (27%), Positives = 58/115 (49%), Gaps = 14/115 (12%)

Query: 185 QMEEERTKVLIA-IEKQKVSEKEAETMKKM----AISEAEKNANVSKILMEQKLSEKDSA 239
           +  EER K+  A +E+   S  E+E M+KM    +I++ E+   +   L E ++  +D+ 
Sbjct: 100 ERSEERLKIATAKLEEASQSADESERMRKMLEHRSITDEERMDGLENQLKEARMMAEDAD 159

Query: 240 RRQEEIENAMYLAREKSLADADFYRVIKEAEANRLKLTPEFLELKFIESIANNTK 294
           R+ +E+      AR+ ++ +AD  R  + AE    K+     EL+    + NN K
Sbjct: 160 RKYDEV------ARKLAMVEADLERAEERAETGESKIVELEEELRV---VGNNLK 205


>M4K4_MOUSE (P97820) Mitogen-activated protein kinase kinase kinase
           kinase 4 (EC 2.7.1.37) (MAPK/ERK kinase kinase kinase 4)
           (MEK kinase kinase 4) (MEKKK 4) (HPK/GCK-like kinase
           HGK) (Nck interacting kinase)
          Length = 1233

 Score = 39.7 bits (91), Expect = 0.011
 Identities = 43/192 (22%), Positives = 78/192 (40%), Gaps = 42/192 (21%)

Query: 134 QQVYIDVFDQIDEKMKDALQVDCTRYAPGIEIIGVRVTKPNIPE---------------S 178
           +QV I + D ID   K   + D T Y    E  G    +  +PE               +
Sbjct: 295 RQVRIQLKDHIDRTRKKRGEKDETEY----EYSGSEEEEEEVPEQEGEPSSIVNVPGEST 350

Query: 179 IRHNFEQMEEERTKVLIAIEKQKVSE----KEAETMKKMAISEAEKNANVSKILM----- 229
           +R +F ++++E  +   A+ +Q++ +    +E E  K+  ++E +K     K        
Sbjct: 351 LRRDFLRLQQENKERSEALRRQQLLQEQQLREQEEYKRQLLAERQKRIEQQKEQRRRLEE 410

Query: 230 --------------EQKLSEKDSARRQEEIENAMYLAREKSLADADFYRVIKEAEANRLK 275
                         EQ+  E++  RR EE+E       E+  A+ +  RV +E E  R +
Sbjct: 411 QQRREREARRQQEREQRRREQEEKRRLEELERRRKEEEERRRAEEEKRRVEREQEYIRRQ 470

Query: 276 LTPEFLELKFIE 287
           L  E   L+ ++
Sbjct: 471 LEEEQRHLEILQ 482


>HFLC_HAEIN (P44545) HflC protein (EC 3.4.-.-)
          Length = 295

 Score = 39.7 bits (91), Expect = 0.011
 Identities = 55/249 (22%), Positives = 98/249 (39%), Gaps = 45/249 (18%)

Query: 44  ITEPGFHMKMPFLTQFEPVQVTLQTDEVTDIPCGTKGGVMIVFGKIEVVNRLHKESVYET 103
           + EPG H K+P +   +          V D    T  G    F  +E  + L    V   
Sbjct: 47  VYEPGLHFKVPLIDSIK----------VLDARIRTLDGSATRFVTVEKKDLLVDSYVKWK 96

Query: 104 LLNYGVQYDKTWIYD----------KIHHEINQFCSSHSLQQVYIDVFDQIDEKMKDALQ 153
           + ++G  Y  T   D          K++  +     S +++ +      ++ E  K AL 
Sbjct: 97  ISDFGRFYTSTGGGDYAQAANLLSRKVNDRLRSEIGSRTIKDIVSGTRGELMEGAKKALS 156

Query: 154 VDCTRYAP-GIEIIGVRVTKPNIPESIRHN-FEQMEEERTKVLIAIEKQKVSEKEAETMK 211
                 A  GIE+I VRV + N+P+ +  + +++M  ER  V          E  ++  +
Sbjct: 157 SGQDSTAELGIEVIDVRVKQINLPDEVSSSIYQRMRAERDAV--------AREHRSQGKE 208

Query: 212 KMAISEAEKNANVSKILMEQKLSEKDSARRQEEIENAMYLAREKSLADA--------DFY 263
           K A  +A+ +  V+ IL        ++ +  +E+  +   A  K  +DA         F 
Sbjct: 209 KAAFIQADVDRKVTLIL-------ANANKTAQELRGSGDAAAAKLYSDAFAQEPQFFTFV 261

Query: 264 RVIKEAEAN 272
           R +K  EA+
Sbjct: 262 RSLKAYEAS 270


>TPM_LEPDS (Q9NFZ4) Tropomyosin (Allergen Lep d 10)
          Length = 284

 Score = 39.3 bits (90), Expect = 0.014
 Identities = 31/118 (26%), Positives = 58/118 (48%), Gaps = 16/118 (13%)

Query: 184 EQMEEERTKVLIA---IEKQKVSEKEAETMKKM----AISEAEKNANVSKILMEQKLSEK 236
           E +E    ++ IA   +E+   S  E+E M+KM    +I++ E+   +   L E ++  +
Sbjct: 97  EDLERSEGRLKIATSKLEEASQSADESERMRKMLEHRSITDEERMEGLESQLKEARMMAE 156

Query: 237 DSARRQEEIENAMYLAREKSLADADFYRVIKEAEANRLKLTPEFLELKFIESIANNTK 294
           D+ R+ +E+      AR+ ++ +AD  R  + AE    K+     EL+    + NN K
Sbjct: 157 DADRKYDEV------ARKLAMVEADLERAEERAETGESKIVELEEELRV---VGNNLK 205


>M4K4_HUMAN (O95819) Mitogen-activated protein kinase kinase kinase
           kinase 4 (EC 2.7.1.37) (MAPK/ERK kinase kinase kinase 4)
           (MEK kinase kinase 4) (MEKKK 4) (HPK/GCK-like kinase
           HGK) (Nck interacting kinase)
          Length = 1239

 Score = 39.3 bits (90), Expect = 0.014
 Identities = 43/192 (22%), Positives = 78/192 (40%), Gaps = 42/192 (21%)

Query: 134 QQVYIDVFDQIDEKMKDALQVDCTRYAPGIEIIGVRVTKPNIPE---------------S 178
           +QV I + D ID   K   + D T Y    E  G    +  +PE               +
Sbjct: 296 RQVRIQLKDHIDRTRKKRGEKDETEY----EYSGSEEEEEEVPEQEGEPSSIVNVPGEST 351

Query: 179 IRHNFEQMEEERTKVLIAIEKQKVSE----KEAETMKKMAISEAEKNANVSKILM----- 229
           +R +F ++++E  +   A+ +Q++ +    +E E  K+  ++E +K     K        
Sbjct: 352 LRRDFLRLQQENKERSEALRRQQLLQEQQLREQEEYKRQLLAERQKRIEQQKEQRRRLEE 411

Query: 230 --------------EQKLSEKDSARRQEEIENAMYLAREKSLADADFYRVIKEAEANRLK 275
                         EQ+  E++  RR EE+E       E+  A+ +  RV +E E  R +
Sbjct: 412 QQRREREARRQQEREQRRREQEEKRRLEELERRRKEEEERRRAEEEKRRVEREQEYIRRQ 471

Query: 276 LTPEFLELKFIE 287
           L  E   L+ ++
Sbjct: 472 LEEEQRHLEVLQ 483


>KI21_STRPU (P46871) Kinesin-II 95 kDa subunit (KRP-85/95 95 kDa
           subunit)
          Length = 742

 Score = 38.9 bits (89), Expect = 0.018
 Identities = 28/108 (25%), Positives = 51/108 (46%), Gaps = 2/108 (1%)

Query: 177 ESIRHNFEQMEEERTKVLIAIEKQKVSEKEAETMKKMAISEAEKNANVSKILMEQKLSEK 236
           E I  N   + EE+ K+L  ++K++   K+    K+M   E +  A  SK+L+  K    
Sbjct: 423 EKIMANQSMIAEEKQKLLSEVQKRQGEIKKEHQQKEML--EGKIKAMESKLLVGGKSIVD 480

Query: 237 DSARRQEEIENAMYLAREKSLADADFYRVIKEAEANRLKLTPEFLELK 284
            +  +Q +IE    L  E+   + D  R +KE +   +++   F  L+
Sbjct: 481 HTNEQQRKIEEQRLLLAEEKNRERDMERKLKEQDDKTVEIEGTFSSLQ 528


>DNAK_VIBCH (O34241) Chaperone protein dnaK (Heat shock protein 70)
           (Heat shock 70 kDa protein) (HSP70)
          Length = 635

 Score = 38.1 bits (87), Expect = 0.031
 Identities = 35/142 (24%), Positives = 63/142 (43%), Gaps = 18/142 (12%)

Query: 147 KMKDALQVDCTRYAPGIEIIGVRVTK-----PNIPESIRHNFEQMEEERTKVLIAI---- 197
           ++KD L +D T  + GIE +G  +TK       IP      F   E+ ++ V I +    
Sbjct: 384 EVKDVLLLDVTPLSLGIETMGGVMTKLIEKNTTIPTKANQVFSTAEDNQSAVTIHVLQGE 443

Query: 198 EKQKVSEKEAETMKKMAISEAEKNANVSKILMEQK------LSEKDSARRQEEIENAMYL 251
            KQ +  K         I+ A +     +++ +        +S KD   +Q   E  + +
Sbjct: 444 RKQAMYNKSLGQFNLEGINPAPRGMPQIEVIFDLDADGILHVSAKD---KQTGKEQKITI 500

Query: 252 AREKSLADADFYRVIKEAEANR 273
                L+DA+  ++++EAEAN+
Sbjct: 501 QASGGLSDAEIEKMVQEAEANK 522


>YAFA_SCHPO (Q09863) Hypothetical protein C29E6.10c in chromosome I
          Length = 1085

 Score = 37.7 bits (86), Expect = 0.040
 Identities = 29/146 (19%), Positives = 70/146 (47%), Gaps = 11/146 (7%)

Query: 184 EQMEEERTKVLIAIEKQKVSEKEAETMKKMAISEAEKNANVSKILMEQKLSEKDSAR--- 240
           ++++ E+ K    +E+QK  EK+ +  ++  + + ++ A+  K+  EQ+L E++  R   
Sbjct: 644 QRLKREQEKKQQELERQKREEKQKQKEREKKLKKQQQEADREKMAREQRLREEEEKRILE 703

Query: 241 ---RQEEIENAMYLAREKSLADADFYRVIKEAEANRLKLTPEFLELKFIE---SIANNTK 294
              R+E+++      R + L + +     KE      K+   F   +  E       +++
Sbjct: 704 ERKRREKLDKEEEERRRRELLEKESEE--KERRLREAKIAAFFAPNQTKEGSDGCTTSSQ 761

Query: 295 IFFGDKIPNMILDQRLLGNFLVEEVP 320
           +   +K  +++ D+  L + L++ VP
Sbjct: 762 LGLFEKKGDLVNDEDKLSSHLLDSVP 787


>TPM_SCHHA (Q26503) Tropomyosin
          Length = 284

 Score = 37.7 bits (86), Expect = 0.040
 Identities = 47/208 (22%), Positives = 87/208 (41%), Gaps = 15/208 (7%)

Query: 88  KIEVVNRLHKESVYETLLNYGVQYDKTWIYDKIHHEINQFCSSHSLQQVYID-VFDQIDE 146
           K+E  N + +   YE LL       K    +K   EI +  +     Q+  D V + + E
Sbjct: 12  KLEKENAMERAVQYEELLK-----KKEEEREKRESEIAELNTKMKQAQIDCDEVQETLQE 66

Query: 147 KMKDALQVDCTRYAPGIEIIGVRVTKPNIPESIRHNFEQMEEERTKVLIAIEKQKVSEKE 206
           +M    + D        E+  +      + E +  +  ++ E  TK+  A +  + SE+ 
Sbjct: 67  QMNKLEETDKRATNAEAEVAAMTRRIRLLEEDLEVSSSRLTETLTKLEEASKTAEESERG 126

Query: 207 AETMKKMAISEAEKNANVSKILMEQKLSEKDSARRQEEIENAMYLAREKSLADADFYRVI 266
            + ++  +I++ E+   +     E K   +D+ R+ +E       AR+ ++A+ DF R  
Sbjct: 127 RKDLEIRSIADDERLNQLEDQQKEAKYIAEDADRKYDE------AARKLAIAEVDFKRAE 180

Query: 267 KEAEANRLKLTPEFLELKFIESIANNTK 294
              EA   K+     EL+    I NN K
Sbjct: 181 ARLEAAESKIVELEEELRV---IGNNMK 205


>TPM_CHAFE (Q9N2R3) Tropomyosin (Allergen Cha f 1) (Cha f I)
           (Fragment)
          Length = 264

 Score = 37.7 bits (86), Expect = 0.040
 Identities = 37/153 (24%), Positives = 73/153 (47%), Gaps = 18/153 (11%)

Query: 143 QIDEKMKDALQVDCTRYAPG-IEIIGVRVTKPNIPESIRHNFEQMEEERTKVLIAIEKQK 201
           ++DEK K ALQ      A G +  +  R+  P   E +  + E++    TK+  A +   
Sbjct: 70  KLDEKEK-ALQ-----NAEGEVAALNRRIQLPE--EDLERSEERLNTATTKLAEASQAAD 121

Query: 202 VSEKEAETMKKMAISEAEKNANVSKILMEQKLSEKDSARRQEEIENAMYLAREKSLADAD 261
            SE+  + ++  ++S+ E+   +   L E +   +++ R+ +E+      AR+ ++ +AD
Sbjct: 122 ESERMRKVLENRSLSDEERMDALENQLKEARFLAEEADRKYDEV------ARKLAMVEAD 175

Query: 262 FYRVIKEAEANRLKLTPEFLELKFIESIANNTK 294
             R  + AE+   K+     EL+    + NN K
Sbjct: 176 LERAEERAESGESKIVELEEELRV---VGNNLK 205


>TPM1_CAEEL (Q22866) Tropomyosin isoforms 1/2
          Length = 284

 Score = 37.7 bits (86), Expect = 0.040
 Identities = 30/118 (25%), Positives = 57/118 (47%), Gaps = 16/118 (13%)

Query: 184 EQMEEERTKVLIAIEKQKV-------SEKEAETMKKMAISEAEKNANVSKILMEQKLSEK 236
           E++E    ++ IA EK +        SE+  + M+  ++ + E+   V   L E +L  +
Sbjct: 97  EELERAEERLKIATEKLEEATHNVDESERVRKVMENRSLQDEERANTVEAQLKEAQLLAE 156

Query: 237 DSARRQEEIENAMYLAREKSLADADFYRVIKEAEANRLKLTPEFLELKFIESIANNTK 294
           ++ R+ +E+      AR+ ++ +AD  R  + AEA   K+     EL+    + NN K
Sbjct: 157 EADRKYDEV------ARKLAMVEADLERAEERAEAGENKIVELEEELRV---VGNNLK 205


>MYO6_MOUSE (Q64331) Myosin VI
          Length = 1265

 Score = 37.7 bits (86), Expect = 0.040
 Identities = 33/143 (23%), Positives = 67/143 (46%), Gaps = 15/143 (10%)

Query: 138 IDVFDQIDEKMKDALQVDCTRYAPGIEI----IGVRVTKPNIP-ESIRHNFEQMEEERTK 192
           +D F+++   +KD  + +  R    +EI    +  + T   +  E I+  ++ + +    
Sbjct: 853 LDKFNEVVSALKDG-KPEVNRQIKNLEISIDALMAKFTSTMMTREQIQKEYDALVKSSED 911

Query: 193 VLIAIEKQKVSEKEAETMKKMAISEAEKNANVSKILMEQKLSEKDSARRQEEIENAMYLA 252
           +L A++K+K  E+EAE ++++   E EK          ++  E +  RR+EE E  M L 
Sbjct: 912 LLSALQKKKQQEEEAERLRRIQ-EEMEKE--------RKRREEDEERRRKEEEERRMKLE 962

Query: 253 REKSLADADFYRVIKEAEANRLK 275
            E      +  R  +E +  R++
Sbjct: 963 MEPKRKQEEEERKKREDDEKRIQ 985


>MYO6_HUMAN (Q9UM54) Myosin VI
          Length = 1285

 Score = 37.7 bits (86), Expect = 0.040
 Identities = 26/103 (25%), Positives = 50/103 (48%), Gaps = 9/103 (8%)

Query: 177 ESIRHNFEQMEEERTKVLIAIEKQKVSEKEAETMKKMAISEAEKNANVSKILMEQKLSEK 236
           E I+  ++ + +   ++L A++K+K  E+EAE ++++   E EK          ++  E 
Sbjct: 893 EQIQKEYDALVKSSEELLSALQKKKQQEEEAERLRRIQ-EEMEKE--------RKRREED 943

Query: 237 DSARRQEEIENAMYLAREKSLADADFYRVIKEAEANRLKLTPE 279
           +  RR+EE E  M L  E      +  R  +E +  R++   E
Sbjct: 944 EKRRRKEEEERRMKLEMEAKRKQEEEERKKREDDEKRIQAEVE 986


>INCE_HUMAN (Q9NQS7) Inner centromere protein
          Length = 919

 Score = 37.7 bits (86), Expect = 0.040
 Identities = 36/137 (26%), Positives = 64/137 (46%), Gaps = 15/137 (10%)

Query: 143 QIDEKMKDALQVDCTRYAPGIEIIGVRVTKPNIPESIRHNFEQM----EEERTKVLIAIE 198
           ++D K K+  +++  R     E    ++ +  + E  R   E++    EE   KVL A E
Sbjct: 527 RMDPKEKERQRLENLRRKEEAE----QLRRQKVEEDKRRRLEEVKLKREERLRKVLQARE 582

Query: 199 K--QKVSEKEAETMKKMAISEAEKNANVSKILMEQKLSEKDSARRQEEIENAMYLAREKS 256
           +  Q   EK+ +  +K A  + +      + L E+K  +K +A++ EE+E     AR K 
Sbjct: 583 RVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVE-----ARRKQ 637

Query: 257 LADADFYRVIKEAEANR 273
             DA   R +++ E  R
Sbjct: 638 EEDARRLRWLQQEEEER 654



 Score = 32.7 bits (73), Expect = 1.3
 Identities = 32/140 (22%), Positives = 64/140 (44%), Gaps = 9/140 (6%)

Query: 141 FDQIDEKMKDA-----LQVDCTRYAPGIEIIGVRVTKPNIPESIRHNFEQMEEERTKVLI 195
           F QIDEK + A      +    + A   ++  V   +    ++ R  + Q EEE  +   
Sbjct: 599 FAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEDARRLRWLQQEEEERRHQE 658

Query: 196 AIEKQKVSEKEAETMKKMAISE--AEKNANVSKILMEQKLSEKDSARRQEEIENAMYLAR 253
            ++K+K  E+E E ++K A ++  AE+     +    ++   ++  RR++E        +
Sbjct: 659 LLQKKK--EEEQERLRKAAEAKRLAEQREQERREQERREQERREQERREQERREQERREQ 716

Query: 254 EKSLADADFYRVIKEAEANR 273
           E+ LA+ +  R  +  +A R
Sbjct: 717 ERQLAEQERRREQERLQAER 736


>YI73_AQUAE (O67720) Hypothetical protein AQ_1873
          Length = 407

 Score = 37.4 bits (85), Expect = 0.052
 Identities = 47/175 (26%), Positives = 77/175 (43%), Gaps = 20/175 (11%)

Query: 123 EINQFCSSHSLQQVYIDVFDQIDEKMKDALQVDCTRYAPGIEIIGVRVTKPNIPESIRHN 182
           EIN+  S     Q Y+ ++D++         VD     P  +++ +R + P   E IR  
Sbjct: 58  EINELYSKKFKNQKYVILYDEL-------FPVDPKNILPPNKVLVLRDSPPE--EIIRRA 108

Query: 183 FEQMEEERTKVLIAIEKQKVSEKEAETMKKMAISEAEK--NANVSKILMEQKLSEKDS-- 238
            E+ +EE  +  I I      E+E +T KK    E E+   A V  +  ++KL++  +  
Sbjct: 109 LEEKKEETKEEGIEIGASVPVEEELKTEKKEEKVEKEETGKAKVLVVSFDKKLTDNITNA 168

Query: 239 --ARRQEEIENAMYLAREKSL-ADADFYRVIKE--AEANRLKL--TPEFLELKFI 286
              +   E+   +   +EK L AD   Y  I    AE N ++L   P+  E  FI
Sbjct: 169 LKGKFSVEVVRNIKSVKEKGLEADIIVYDAISGSIAEKNLMELAEVPQLREKHFI 223



 Score = 32.0 bits (71), Expect = 2.2
 Identities = 35/137 (25%), Positives = 62/137 (44%), Gaps = 17/137 (12%)

Query: 172 KPNIPESIRHNFEQMEEERTKVLIAIEKQKVSEKEAETMKKMAISEAEKNANVSKILMEQ 231
           +  IPE +    E+++EE+       E  ++ EK        AIS  EK     ++L E 
Sbjct: 284 REEIPEEVPQEVEEIKEEKP------EMSEIKEKTE------AISTKEKTPEAVQVLAE- 330

Query: 232 KLSEKDSARR--QEEIENAMYLAREKSLADA-DFYRVIKEAEANRLKLTPEFLELKFIES 288
           KLS++   R    E I   ++  RE+  A+  D+ + + E+   R ++   F E+   + 
Sbjct: 331 KLSDEKFIRSLLVEAISKELHGVREEIKAEVRDYIKNVLES-IIREEIERAFAEVGVAKI 389

Query: 289 IANNTKIFFGDKIPNMI 305
           I   TK    +KI  ++
Sbjct: 390 IREETKRIVEEKIKELL 406


>TPM_METEN (Q25456) Tropomyosin (Allergen Met e 1) (Met e I)
          Length = 274

 Score = 37.4 bits (85), Expect = 0.052
 Identities = 26/120 (21%), Positives = 57/120 (46%), Gaps = 9/120 (7%)

Query: 175 IPESIRHNFEQMEEERTKVLIAIEKQKVSEKEAETMKKMAISEAEKNANVSKILMEQKLS 234
           + E +  + E++    TK+  A +    SE+  + ++  ++S+ E+   +   L E +  
Sbjct: 85  LEEDLERSEERLNTATTKLAEASQAADESERMRKVLENRSLSDEERMDALENQLKEARFL 144

Query: 235 EKDSARRQEEIENAMYLAREKSLADADFYRVIKEAEANRLKLTPEFLELKFIESIANNTK 294
            +++ R+ +E+      AR+ ++ +AD  R  + AE    K+     EL+    + NN K
Sbjct: 145 AEEADRKYDEV------ARKLAMVEADLERAEERAETGESKIVELEEELRV---VGNNLK 195


  Database: sprot
    Posted date:  Nov 25, 2004 10:54 AM
  Number of letters in database: 59,974,054
  Number of sequences in database:  164,201
  
Lambda     K      H
   0.318    0.135    0.378 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 36,721,492
Number of Sequences: 164201
Number of extensions: 1523640
Number of successful extensions: 7194
Number of sequences better than 10.0: 331
Number of HSP's better than 10.0 without gapping: 33
Number of HSP's successfully gapped in prelim test: 307
Number of HSP's that attempted gapping in prelim test: 6663
Number of HSP's gapped (non-prelim): 758
length of query: 331
length of database: 59,974,054
effective HSP length: 111
effective length of query: 220
effective length of database: 41,747,743
effective search space: 9184503460
effective search space used: 9184503460
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 66 (30.0 bits)