BLASTP 2.2.2 [Dec-14-2001]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= AC146527.1 - phase: 0 
         (468 letters)

Database: sprot 
           164,201 sequences; 59,974,054 total letters

Searching..................................................done

                                                                   Score     E
Sequences producing significant alignments:                        (bits)  Value

KYK1_DICDI (P18160) Non-receptor tyrosine kinase spore lysis A (...    99  2e-20
YGX7_YEAST (P53076) Hypothetical 108.2 kDa protein in SAP4-OST5 ...    56  2e-07
CT11_HUMAN (Q9NWU2) Protein C20orf11                                   55  3e-07
CT11_MOUSE (Q9D7M1) Protein C20orf11 homolog                           55  5e-07
YM40_YEAST (Q03212) Hypothetical 62.5 kDa protein in ALD2-DDR48 ...    54  9e-07
DDX1_DROME (Q9VNV3) ATP-dependent helicase DDX1 (DEAD box protei...    49  4e-05
ROU_HUMAN (Q00839) Heterogenous nuclear ribonucleoprotein U (hnR...    45  5e-04
YKM4_YEAST (P32343) Hypothetical 65.1 kDa protein in RRN3-SRP21 ...    42  0.003
RYR1_RABIT (P11716) Ryanodine receptor 1 (Skeletal muscle-type r...    41  0.006
RYR1_HUMAN (P21817) Ryanodine receptor 1 (Skeletal muscle-type r...    40  0.010
RYR1_PIG (P16960) Ryanodine receptor 1 (Skeletal muscle-type rya...    40  0.013
Y208_BORBU (O51226) Hypothetical protein BB0208                        39  0.029
DDX1_HUMAN (Q92499) ATP-dependent helicase DDX1 (DEAD-box protei...    39  0.037
RYR2_RABIT (P30957) Ryanodine receptor 2 (Cardiac muscle-type ry...    37  0.11
RYR2_HUMAN (Q92736) Ryanodine receptor 2 (Cardiac muscle-type ry...    35  0.41
RYR3_HUMAN (Q15413) Ryanodine receptor 3 (Brain-type ryanodine r...    35  0.54
N205_HUMAN (Q92621) Nuclear pore complex protein Nup205 (Nucleop...    34  0.71
Y134_HAEIN (P43952) Hypothetical protein HI0134                        34  0.92
TARA_BACSU (Q8RKI7) Putative N-acetylmannosaminyltransferase (EC...    33  1.6
T2EA_YEAST (P36100) Transcription initiation factor IIE, alpha s...    31  6.0

>KYK1_DICDI (P18160) Non-receptor tyrosine kinase spore lysis A (EC
           2.7.1.112) (Tyrosine-protein kinase 1)
          Length = 1584

 Score = 99.0 bits (245), Expect = 2e-20
 Identities = 65/203 (32%), Positives = 95/203 (46%), Gaps = 31/203 (15%)

Query: 49  ESPSELNTINSSGGFVVVATDKLSVKYT------SVNLHGHDVGVIQANKVA-------- 94
           E PS+ +TI  SGG  ++ ++ L  K        S   + H   V+  N+ A        
Sbjct: 184 EKPSKQSTIKDSGGSSIIPSEDLIPKEEFEVCRWSEKKNYHGKHVVVRNRTAFLPLDSPK 243

Query: 95  ----------PMKRIVYYFEIFVKDAGVKGQVSIGFTTESFKMRRQPGWEANSCGYHGDD 144
                     P      YFE+ + D   KGQ+SIG     +      GW   S GYH DD
Sbjct: 244 DTIGGVRATQPFGEGFCYFEVII-DQLDKGQLSIGLANLEYPTFYHVGWMPRSYGYHNDD 302

Query: 145 GFLYR-----GQGKGEAFGPTYTTGDIVGAGINYAAQEFFFTKNGQVVGTVFKEMKGPLF 199
           G  +R     G  +GE++G +Y  GDI+G G+++ ++E FFTKNG  +GT F  + G  +
Sbjct: 303 GRKFRWREEPGVNEGESYGSSYKKGDIIGCGLSFTSREIFFTKNGMYLGTAFSNVYGVFY 362

Query: 200 PTVAVHSQNEEVHVNFGQKPFTF 222
           P+VA +     +   FG  PF F
Sbjct: 363 PSVAFNEPGISITGVFG-PPFKF 384



 Score = 77.4 bits (189), Expect = 7e-14
 Identities = 42/127 (33%), Positives = 68/127 (53%), Gaps = 3/127 (2%)

Query: 90  ANKVAPMKRIVYYFEIFVKDAGVKGQVSIGFTTESFKMRRQPGWEANSCGYHGDDGFLYR 149
           A    P      YFE+F+ + G   ++  G TT    +   PG    S GY GD G  Y 
Sbjct: 49  AKSTQPFSSSFTYFELFITN-GNGDKICFGLTTNDHPIEVYPGNYQGSYGYSGD-GKCYF 106

Query: 150 GQGKGEAFGPTYTTGDIVGAGINYAAQEFFFTKNGQVVGTVFKEMK-GPLFPTVAVHSQN 208
           G  +G  +GP++++GD+VG G + +++  +FTKNG  +G   +++    L+PTV + +  
Sbjct: 107 GTNEGRVYGPSFSSGDVVGCGYDSSSKTLYFTKNGVYLGVAAQKVNLIGLYPTVGLQNPG 166

Query: 209 EEVHVNF 215
           E V +NF
Sbjct: 167 ESVVINF 173



 Score = 64.3 bits (155), Expect = 6e-10
 Identities = 34/112 (30%), Positives = 61/112 (54%), Gaps = 9/112 (8%)

Query: 100 VYYFEIFVKDAGVKGQVSIGFTTESFKMRRQPGWEANSCGYHGDDGFLYRGQGKGEAFGP 159
           + YFE++++    KG +++G +  ++   +  G E  S G+   +G  Y G   GE +GP
Sbjct: 749 ICYFEVYLEGHDKKGSITVGLSHSTYPFIKHIGREPKSYGF-SSEGEKYGGSEIGEPYGP 807

Query: 160 TYT-TGD------IVGAGINYAAQEFFFTKNGQVVGTVFKEM-KGPLFPTVA 203
            +   GD      ++G GIN + ++ FFTKNG  +G  F  +   PL+P+++
Sbjct: 808 FFFFDGDSIASSCVIGCGINTSTRDIFFTKNGHYLGVAFSRVTSDPLYPSIS 859


>YGX7_YEAST (P53076) Hypothetical 108.2 kDa protein in SAP4-OST5
           intergenic region
          Length = 958

 Score = 56.2 bits (134), Expect = 2e-07
 Identities = 49/175 (28%), Positives = 78/175 (44%), Gaps = 10/175 (5%)

Query: 132 GWEANSCGYHGDDGFLYRGQGKGEAFGPTYTTGDIVGAGINYAAQEFFFTKNGQVVGTVF 191
           G++ N  GY G DG +     + + +   +   D++G GIN+     FFTKNG  +G  F
Sbjct: 504 GFDLNVFGYCGFDGLITNSTEQSKEYAKPFGRDDVIGCGINFIDGSIFFTKNGIHLGNAF 563

Query: 192 KEMKGPLF-PTVAVHSQNEEVHVNFG-QKPFTFDLKEYEAQERMKQQIKIEEVPVSPNAS 249
            ++    F P VA+   N  +  NFG  + F FD+  Y  Q++ K  +  E +       
Sbjct: 564 TDLNDLEFVPYVALRPGN-SIKTNFGLNEDFVFDIIGY--QDKWK-SLAYEHICRGRQMD 619

Query: 250 YGIVRSYLLHYGYEDTLNSFDEASRST---IPPINIVQENGIDDQETTYALNHRK 301
             I   +      ED   +  E ++ST      ++I QE+G    + T  LN  K
Sbjct: 620 VSI-EEFDSDESEEDETENGPEENKSTNVNEDLMDIDQEDGAAGNKDTKKLNDEK 673



 Score = 35.4 bits (80), Expect = 0.32
 Identities = 43/197 (21%), Positives = 77/197 (38%), Gaps = 29/197 (14%)

Query: 246 PNASYGIVRSYLLHYGYEDTLNSFDEASRSTIPPIN--------IVQENGIDDQETTYAL 297
           PN    ++  YL+H G  D    F +  +     +N        +++ N     +    +
Sbjct: 711 PNTLNVMINDYLIHEGLVDVAKGFLKDLQKDAVNVNGQHSESKDVIRHNERQIMKEERMV 770

Query: 298 NHRKTLRQLIRDGEIDAAFGKLREWYPQIAEDNTSAMCFLLHCQKFIELVRVGA------ 351
             R+ LR LI  G+I      +    P + ++N   + F L    ++ +++  +      
Sbjct: 771 KIRQELRYLINKGQISKCINYIDNEIPDLLKNNLE-LVFELKLANYLVMIKKSSSKDDDE 829

Query: 352 LEEAVKYGRIELSSFFGLSL---------FEDIVQDCVALLAYERPLESA----VGYLLK 398
           +E  +  G+ ELS+ F             F   + +  ALLAY  PL  A     GYL  
Sbjct: 830 IENLILKGQ-ELSNEFIYDTKIPQSLRDRFSGQLSNVSALLAYSNPLVEAPKEISGYLSD 888

Query: 399 DSQREVVADAVNAMILS 415
           +  +E +    N  IL+
Sbjct: 889 EYLQERLFQVSNNTILT 905


>CT11_HUMAN (Q9NWU2) Protein C20orf11
          Length = 228

 Score = 55.5 bits (132), Expect = 3e-07
 Identities = 44/165 (26%), Positives = 79/165 (47%), Gaps = 17/165 (10%)

Query: 252 IVRSYLLHYGYEDTLNSFDEASRSTIPPINIVQENGIDDQETTYALNHRKTLRQLIRDGE 311
           ++ +YL+  G+++    F               E+GI+       L+ R  +R++I  G+
Sbjct: 32  LIMNYLVTEGFKEAAEKFR-------------MESGIEPSVDLETLDERIKIREMILKGQ 78

Query: 312 IDAAFGKLREWYPQIAEDNTSAMCFLLHCQKFIELVRVGALEEAVKYGRIELSSFFGLSL 371
           I  A   +   +P++ + N   + F L  Q  IEL+R    E A+++ + +L+   G   
Sbjct: 79  IQEAIALINSLHPELLDTNRY-LYFHLQQQHLIELIRQRETEAALEFAQTQLAEQ-GEES 136

Query: 372 FEDI--VQDCVALLAYERPLESAVGYLLKDSQREVVADAVNAMIL 414
            E +  ++  +ALLA++ P ES  G LL   QR+ V   VN  +L
Sbjct: 137 RECLTEMERTLALLAFDSPEESPFGDLLHTMQRQKVWSEVNQAVL 181


>CT11_MOUSE (Q9D7M1) Protein C20orf11 homolog
          Length = 228

 Score = 54.7 bits (130), Expect = 5e-07
 Identities = 44/165 (26%), Positives = 79/165 (47%), Gaps = 17/165 (10%)

Query: 252 IVRSYLLHYGYEDTLNSFDEASRSTIPPINIVQENGIDDQETTYALNHRKTLRQLIRDGE 311
           ++ +YL+  G+++    F               E+GI+       L+ R  +R++I  G+
Sbjct: 32  LIMNYLVTEGFKEAAEKFR-------------MESGIEPSVDLETLDERIKIREMILKGQ 78

Query: 312 IDAAFGKLREWYPQIAEDNTSAMCFLLHCQKFIELVRVGALEEAVKYGRIELSSFFGLSL 371
           I  A   +   +P++ + N   + F L  Q  IEL+R    E A+++ + +L+   G   
Sbjct: 79  IQEAIALINSLHPELLDTNRY-LYFHLQQQHLIELIRQRETEAALEFAQTQLAEQ-GEES 136

Query: 372 FEDI--VQDCVALLAYERPLESAVGYLLKDSQREVVADAVNAMIL 414
            E +  ++  +ALLA++ P ES  G LL   QR+ V   VN  +L
Sbjct: 137 RECLTEMERTLALLAFDSPEESPFGDLLHMMQRQKVWSEVNQAVL 181


>YM40_YEAST (Q03212) Hypothetical 62.5 kDa protein in ALD2-DDR48
           intergenic region
          Length = 550

 Score = 53.9 bits (128), Expect = 9e-07
 Identities = 62/228 (27%), Positives = 93/228 (40%), Gaps = 34/228 (14%)

Query: 65  VVATDKLSVKYTSVNLHGHDVGVIQANKVAPMKRIVYY--FEIFVKDAGV-------KGQ 115
           V+  +K  V + + N        I  N   P    VYY  F+IF  D  +       KG 
Sbjct: 206 VIVENKTEVSFLNYNYDAS----ISTNLPIPCINKVYYCEFKIFETDGPLNSDENVSKGV 261

Query: 116 VSIGFTTESFKMRRQPGWEANSCGYHGD------DGFLYRGQGKGEAFGPTYTTGDIVGA 169
           +S G +T+ +   R PG   +S  Y  +      D F    Q +     P    GDIVG 
Sbjct: 262 ISFGLSTQPYPYFRLPGRHHHSIAYDSNGARRFNDSFKLNEQLR--TLFPQCEKGDIVGI 319

Query: 170 GINYAAQEFFFTKNGQVVG--TVFKEMKG----PLFPTVAVHSQNEEVHVNFGQKPFTFD 223
           G    +   FFT+NG+ +   +V   ++G     L+P +  +    ++HVNFG   F + 
Sbjct: 320 GYRSRSGTVFFTRNGKKLNEKSVGGHIRGWKFQYLYPIIGSNVPC-QIHVNFGTYGFVY- 377

Query: 224 LKEYEAQERMKQQIKIEEVPVSPNASYGIVRSYLLHYGYEDTLNSFDE 271
               EA  +     K   + + P +     +  LL  G ED  N FDE
Sbjct: 378 ---IEANVKKWGYAKSNGIKLPPPSYEDYGKDTLLESGGED--NDFDE 420


>DDX1_DROME (Q9VNV3) ATP-dependent helicase DDX1 (DEAD box protein
           1)
          Length = 727

 Score = 48.5 bits (114), Expect = 4e-05
 Identities = 41/136 (30%), Positives = 62/136 (45%), Gaps = 33/136 (24%)

Query: 101 YYFEIFVKDAGVKGQVSIGFTTESFKMRRQPGWEANSCGYHGDDGFLYRGQGK------- 153
           +YFE  V D G+     +G++T+      Q   +  +C      GF + G GK       
Sbjct: 132 FYFEATVTDEGL---CRVGWSTQ------QANLDLGTCRM----GFGFGGTGKKSNNRQF 178

Query: 154 ---GEAFGPTYTTGDIVGAGINYAAQEFFFTKNGQVVGTVFK----EMKGPLFPTVAVHS 206
              GEAFG      D++G  ++   QE  FTKNGQ +G  F+      K   +P V +  
Sbjct: 179 DDYGEAFGKA----DVIGCLLDLKNQEVSFTKNGQNLGVAFRLPDNLAKETFYPAVVL-- 232

Query: 207 QNEEVHVNFGQKPFTF 222
           +N E+  NFG+  F +
Sbjct: 233 KNAEMQFNFGKTDFKY 248


>ROU_HUMAN (Q00839) Heterogenous nuclear ribonucleoprotein U (hnRNP
           U) (Scaffold attachment factor A) (SAF-A) (pp120)
          Length = 824

 Score = 44.7 bits (104), Expect = 5e-04
 Identities = 57/228 (25%), Positives = 94/228 (41%), Gaps = 24/228 (10%)

Query: 7   KNTIEKPDQDQNQDLGFHFLELSRRKAKLDSEDFEVDDEEKEESPSELNTINSSGGFVVV 66
           K  +++P +D  +    +  E    +AK      E +DE  +++   L+T N    F  +
Sbjct: 242 KRGVKRPREDHGRGYFEYIEENKYSRAKSPQPPVEEEDEHFDDTVVCLDTYNCDLHF-KI 300

Query: 67  ATDKLSVKYTSVNLHGHDVGVIQANKVAPMKRIVYYFEIFVKDAGVKGQVSIGFTTESFK 126
           + D+LS    ++          +A+      ++   FE+ V +   K  V   +T +   
Sbjct: 301 SRDRLSASSLTMESFAFLWAGGRASYGVSKGKVC--FEMKVTE---KIPVRHLYTKDIDI 355

Query: 127 MRRQPGWEANSCG-YHGDDGFLYRGQGKG--------EAFGPTYTTGDIVGAGINYAAQ- 176
              + GW   + G   G++ F Y    KG        E +G  +   D++    N+ +  
Sbjct: 356 HEVRIGWSLTTSGMLLGEEEFSYGYSLKGIKTCNCETEDYGEKFDENDVITCFANFESDE 415

Query: 177 -EFFFTKNGQVVGTVFKEMK-----GPLFPTVAVHSQNEEVHVNFGQK 218
            E  + KNGQ +G  FK  K      PLFP V  H  N  V  NFGQK
Sbjct: 416 VELSYAKNGQDLGVAFKISKEVLAGRPLFPHVLCH--NCAVEFNFGQK 461


>YKM4_YEAST (P32343) Hypothetical 65.1 kDa protein in RRN3-SRP21
           intergenic region
          Length = 579

 Score = 42.4 bits (98), Expect = 0.003
 Identities = 46/174 (26%), Positives = 65/174 (36%), Gaps = 13/174 (7%)

Query: 35  LDSEDFEVDDEEKEES----PSELNTINSSGGFV--VVATDKLSVKYTSVNLHGHDVGVI 88
           LDS+D +   +   +S    PS  + I+  G F+   +  DKL ++++  N     V   
Sbjct: 162 LDSDDQQFIKDRGIQSYFLLPSINDNIDEYGNFLPSFIVQDKLDIQFSKFNKSSSTV--- 218

Query: 89  QANKVAPMKRI-VYYFEIFVKDAGVKGQ--VSIGFTTESFKMRRQPGWEANSCGYHGDDG 145
             N   P  R    YFE+ +     K     SIG TT  +   R PG    S  Y     
Sbjct: 219 -MNYPLPHNRKDAVYFEVKIFRHIQKSNSIFSIGLTTVPYPYFRVPGMAKYSIAYESTGK 277

Query: 146 FLYRGQGKGEAFGPTYTTGDIVGAGINYAAQEFFFTKNGQVVGTVFKEMKGPLF 199
                        P    GD VG G  Y     F T NG+ +  V + +   LF
Sbjct: 278 LRINNPFTASTLLPKLEEGDTVGFGYRYKTGTIFITHNGKKLMDVTQNIGIDLF 331


>RYR1_RABIT (P11716) Ryanodine receptor 1 (Skeletal muscle-type
            ryanodine receptor) (RyR1) (RYR-1) (Skeletal muscle
            calcium release channel)
          Length = 5037

 Score = 41.2 bits (95), Expect = 0.006
 Identities = 36/140 (25%), Positives = 63/140 (44%), Gaps = 12/140 (8%)

Query: 85   VGVIQANKVAPMKRIVYYFEIFVKDAGVKGQVSIGFTTESFKMRRQPGWEANSCGYHGDD 144
            V + +A K   ++   +YFE    +A   G++ +G+     +   + G +  +  ++G  
Sbjct: 1072 VRIFRAEKSYTVQSGRWYFEF---EAVTTGEMRVGWARPELRPDVELGADELAYVFNGHR 1128

Query: 145  GFLYRGQGKGEAFGPTYTTGDIVGAGINYAAQEFFFTKNGQVV------GTVFKEMK-GP 197
            G   R     E FG  + +GD+VG  I+       FT NG+V+       T F+E++ G 
Sbjct: 1129 G--QRWHLGSEPFGRPWQSGDVVGCMIDLTENTIIFTLNGEVLMSDSGSETAFREIEIGD 1186

Query: 198  LFPTVAVHSQNEEVHVNFGQ 217
             F  V      +  H+N GQ
Sbjct: 1187 GFLPVCSLGPGQVGHLNLGQ 1206


>RYR1_HUMAN (P21817) Ryanodine receptor 1 (Skeletal muscle-type
            ryanodine receptor) (RyR1) (RYR-1) (Skeletal muscle
            calcium release channel)
          Length = 5038

 Score = 40.4 bits (93), Expect = 0.010
 Identities = 36/140 (25%), Positives = 62/140 (43%), Gaps = 12/140 (8%)

Query: 85   VGVIQANKVAPMKRIVYYFEIFVKDAGVKGQVSIGFTTESFKMRRQPGWEANSCGYHGDD 144
            V + +A K   ++   +YFE    +A   G++ +G+     +   + G +  +  ++G  
Sbjct: 1071 VRIFRAEKSYTVQSGRWYFEF---EAVTTGEMRVGWARPELRPDVELGADELAYVFNGHR 1127

Query: 145  GFLYRGQGKGEAFGPTYTTGDIVGAGINYAAQEFFFTKNGQVV------GTVFKEMK-GP 197
            G   R     E FG  +  GD+VG  I+       FT NG+V+       T F+E++ G 
Sbjct: 1128 G--QRWHLGSEPFGRPWQPGDVVGCMIDLTENTIIFTLNGEVLMSDSGSETAFREIEIGD 1185

Query: 198  LFPTVAVHSQNEEVHVNFGQ 217
             F  V      +  H+N GQ
Sbjct: 1186 GFLPVCSLGPGQVGHLNLGQ 1205


>RYR1_PIG (P16960) Ryanodine receptor 1 (Skeletal muscle-type
            ryanodine receptor) (RyR1) (RYR-1) (Skeletal muscle
            calcium release channel)
          Length = 5035

 Score = 40.0 bits (92), Expect = 0.013
 Identities = 35/140 (25%), Positives = 63/140 (45%), Gaps = 12/140 (8%)

Query: 85   VGVIQANKVAPMKRIVYYFEIFVKDAGVKGQVSIGFTTESFKMRRQPGWEANSCGYHGDD 144
            V + +A K   ++   +YFE    +A   G++ +G+     +   + G +  +  ++G  
Sbjct: 1072 VRIFRAEKSYAVQSGRWYFEF---EAVTTGEMRVGWARPELRPDVELGADELAYVFNGHR 1128

Query: 145  GFLYRGQGKGEAFGPTYTTGDIVGAGINYAAQEFFFTKNGQVV------GTVFKEMK-GP 197
            G   R     E FG  + +GD+VG  I+       FT NG+V+       T F++++ G 
Sbjct: 1129 G--QRWHLGSELFGRPWQSGDVVGCMIDLTENTIIFTLNGEVLMSDSGSETAFRDIEVGD 1186

Query: 198  LFPTVAVHSQNEEVHVNFGQ 217
             F  V      +  H+N GQ
Sbjct: 1187 GFLPVCSLGPGQVGHLNLGQ 1206


>Y208_BORBU (O51226) Hypothetical protein BB0208
          Length = 581

 Score = 38.9 bits (89), Expect = 0.029
 Identities = 35/168 (20%), Positives = 73/168 (42%), Gaps = 13/168 (7%)

Query: 214 NFGQKPFTFDLKEYEAQE--RMKQQIKIEEVPVSPNASYGIVRSYLLHYGYEDTLNSFDE 271
           N  +K F   +KE+   +   ++ QI +  +   PN  Y        H+ +   +  + +
Sbjct: 409 NKDKKIFCQRMKEFFKSKTFEIQNQIFVYFLSFYPNIEYK-------HFKFISDILLYLD 461

Query: 272 ASRSTIPP----INIVQENGIDDQETTYALNHRKTLRQLIRDGEIDAAFGKLREWYPQIA 327
            ++ TIP     I  +  N +D Q++   +   KT  ++++    +  F  + +   +  
Sbjct: 462 ENKITIPKKIIKIQKINPNQLDYQKSYLLIKSLKTRSRILKIIIKNIRFNLIEKLEDENE 521

Query: 328 EDNTSAMCFLLHCQKFIELVRVGALEEAVKYGRIELSSFFGLSLFEDI 375
           +    AMC+L++C+  +EL     ++   K   +E  SFF   L + I
Sbjct: 522 KKLLPAMCYLIYCENLVELKNNRKIKSNEKNSLLEFISFFKTKLKQKI 569


>DDX1_HUMAN (Q92499) ATP-dependent helicase DDX1 (DEAD-box protein
           1) (DEAD-box protein-retinoblastoma) (DBP-RB)
          Length = 740

 Score = 38.5 bits (88), Expect = 0.037
 Identities = 28/92 (30%), Positives = 45/92 (48%), Gaps = 12/92 (13%)

Query: 145 GFLYRGQGKG------EAFGPTYTTGDIVGAGINYAAQEFFFTKNGQVVGTVFK---EMK 195
           GF + G GK       + +G  +T  D +G  ++       F+KNG+ +G  F+    MK
Sbjct: 164 GFGFGGTGKKSHNKQFDNYGEEFTMHDTIGCYLDIDKGHVKFSKNGKDLGLAFEIPPHMK 223

Query: 196 G-PLFPTVAVHSQNEEVHVNFGQKPFTFDLKE 226
              LFP   +  +N E+  NFG++ F F  K+
Sbjct: 224 NQALFPACVL--KNAELKFNFGEEEFKFPPKD 253


>RYR2_RABIT (P30957) Ryanodine receptor 2 (Cardiac muscle-type
            ryanodine receptor) (RyR2) (RYR-2) (Cardiac muscle
            ryanodine receptor-calcium release channel)
          Length = 4969

 Score = 37.0 bits (84), Expect = 0.11
 Identities = 25/107 (23%), Positives = 51/107 (47%), Gaps = 7/107 (6%)

Query: 82   GHDVGVIQANKVAPMKRIVYYFEIFVKDAGVKGQVSIGFTTESFKMRRQPGWEANSCGYH 141
            G    + +A K   +K   +YFE    +A   G + +G++    +  ++ G +  +  + 
Sbjct: 1082 GERFRIFRAEKTYAVKAGRWYFEF---EAVTSGDMRVGWSRPGCQPDQELGSDERAFAF- 1137

Query: 142  GDDGFLYRGQGKG-EAFGPTYTTGDIVGAGINYAAQEFFFTKNGQVV 187
              DGF  +   +G E +G ++  GD+VG  ++       FT NG+++
Sbjct: 1138 --DGFKAQRWHQGNEHYGRSWQAGDVVGCMVDMNEHTMMFTLNGEIL 1182


>RYR2_HUMAN (Q92736) Ryanodine receptor 2 (Cardiac muscle-type
            ryanodine receptor) (RyR2) (RYR-2) (Cardiac muscle
            ryanodine receptor-calcium release channel) (hRYR-2)
          Length = 4967

 Score = 35.0 bits (79), Expect = 0.41
 Identities = 25/107 (23%), Positives = 50/107 (46%), Gaps = 7/107 (6%)

Query: 82   GHDVGVIQANKVAPMKRIVYYFEIFVKDAGVKGQVSIGFTTESFKMRRQPGWEANSCGYH 141
            G    + +A K   +K   +YFE     AG    + +G++    +  ++ G +  +  + 
Sbjct: 1082 GERFRIFRAEKTYAVKAGRWYFEFETVTAG---DMRVGWSRPGCQPDQELGSDERAFAF- 1137

Query: 142  GDDGFLYRGQGKG-EAFGPTYTTGDIVGAGINYAAQEFFFTKNGQVV 187
              DGF  +   +G E +G ++  GD+VG  ++       FT NG+++
Sbjct: 1138 --DGFKAQRWHQGNEHYGRSWQAGDVVGCMVDMNEHTMMFTLNGEIL 1182


>RYR3_HUMAN (Q15413) Ryanodine receptor 3 (Brain-type ryanodine
            receptor) (RyR3) (RYR-3) (Brain ryanodine
            receptor-calcium release channel)
          Length = 4870

 Score = 34.7 bits (78), Expect = 0.54
 Identities = 26/89 (29%), Positives = 42/89 (46%), Gaps = 5/89 (5%)

Query: 101  YYFEIFVKDAGVKGQVSIGFTTESFKMRRQPGWEANSCGYHGDDGFLYRGQGKGEAFGPT 160
            +YFE  V   G    + +G+     +   + G +  +  + G+ G  +  QG G  FG T
Sbjct: 1087 WYFEFEVVTGG---DMRVGWARPGCRPDVELGADDQAFVFEGNRGQRWH-QGSGY-FGRT 1141

Query: 161  YTTGDIVGAGINYAAQEFFFTKNGQVVGT 189
            +  GD+VG  IN       FT NG+++ T
Sbjct: 1142 WQPGDVVGCMINLDDASMIFTLNGELLIT 1170


>N205_HUMAN (Q92621) Nuclear pore complex protein Nup205
           (Nucleoporin Nup205) (205 kDa nucleoporin)
          Length = 2012

 Score = 34.3 bits (77), Expect = 0.71
 Identities = 32/104 (30%), Positives = 47/104 (44%), Gaps = 4/104 (3%)

Query: 332 SAMCFLLHCQKFIELVRVGALEEAVKYGRIELSSFFGLSLFEDIVQDCVALLAYERPLES 391
           S M  LL+    +EL  +  LEE VK      + F G    E  VQ C+ALL      E+
Sbjct: 804 SLMYHLLNESPMLELA-LSLLEEGVKQ-LDTYAPFPGKKHLEKAVQHCLALLNLTLQKEN 861

Query: 392 AVGYLLKDSQREVVADAVNAMILSTNPNIKVTKNCLHSNLERLL 435
               LL++SQ  ++   +  ++   NP  K   N +  N+ R L
Sbjct: 862 LFMDLLRESQLALIVCPLEQLLQGINPRTKKADNVV--NIARYL 903


>Y134_HAEIN (P43952) Hypothetical protein HI0134
          Length = 391

 Score = 33.9 bits (76), Expect = 0.92
 Identities = 40/164 (24%), Positives = 71/164 (42%), Gaps = 22/164 (13%)

Query: 160 TYTTGDIVGAGINYAAQEFFFTKNGQVVGTVFKEMKGPLFPTVAVHS--QNEEVHVNFGQ 217
           ++++  ++   +N+ AQ      NG+++G    +M    FP    +   QN+E++  F Q
Sbjct: 247 SFSSSSLIQGKLNFLAQ------NGEILGVNLLDMVAQYFPINYNNDLLQNKELNTRFEQ 300

Query: 218 KPFTFDLKEYEAQERMKQQIKIE-EVPVSPNASYGIVRSYLLHYGYEDTLNSFDEASRST 276
               F L+ +  Q ++  + KIE + P       GI+    +    +  LNS D+  ++ 
Sbjct: 301 ----FYLQLFLQQNQLIAE-KIELKTPALLGQGKGIIDLNRMECNVDINLNSTDQRYQNL 355

Query: 277 IPPINIVQENGIDDQETTYALNHRKTLRQLIRDGEIDAAFGKLR 320
             PIN       +     Y +N  K  R  +    IDA   KLR
Sbjct: 356 TLPINFFG----NCNSPQYKINFTKKFRHQL----IDAIKEKLR 391


>TARA_BACSU (Q8RKI7) Putative N-acetylmannosaminyltransferase (EC
           2.4.1.187) (UDP-N-acetylmannosamine transferase)
           (N-acetylglucosaminyldiphospho-undecaprenol
           N-acetyl-beta-D-mannosaminyltransferase)
          Length = 257

 Score = 33.1 bits (74), Expect = 1.6
 Identities = 44/165 (26%), Positives = 65/165 (38%), Gaps = 32/165 (19%)

Query: 18  NQDLGFHFLELSRRKAKLDSEDFEVDDEEKEESPSELNTINSSGGFVVVATDKLSVKYTS 77
           N ++GF  ++  R +A L S DF + D                 G  VV   KL  K   
Sbjct: 40  NPEIGFEAMQNPRYEAVLSSADFILPD-----------------GIGVVMVSKLIGKPLQ 82

Query: 78  VNLHGHDVGVIQANKVAPMKRIVYYFEIFVKDAGVKGQVSIGFTTESFKMRRQPGWEANS 137
             + G+D+     +K    K+ V+++       G    V I  T E  K R  PG E   
Sbjct: 83  SRIAGYDLFTSLLDKADQKKKRVFFY-------GAAKHV-IAETIERVK-RDFPGIEI-- 131

Query: 138 CGYHGDDGFLYRGQGKGEAFGPTYTTGDIVGAGINYAAQEFFFTK 182
            GY   DG++   +   +      +T D+V   + Y  QEFF  K
Sbjct: 132 AGY--SDGYVKDQREVADKIAA--STPDMVFVALGYPNQEFFIHK 172


>T2EA_YEAST (P36100) Transcription initiation factor IIE, alpha
           subunit (TFIIE-alpha) (Transcription factor A large
           subunit) (Factor A 66 kDa subunit)
          Length = 482

 Score = 31.2 bits (69), Expect = 6.0
 Identities = 12/43 (27%), Positives = 28/43 (64%)

Query: 11  EKPDQDQNQDLGFHFLELSRRKAKLDSEDFEVDDEEKEESPSE 53
           E  +++  + L  ++  L++++AKL+ E+ E ++EE++E   E
Sbjct: 347 EMEERENEKTLNDYYAALAKKQAKLNKEEEEEEEEEEDEEEEE 389


  Database: sprot
    Posted date:  Nov 25, 2004 10:54 AM
  Number of letters in database: 59,974,054
  Number of sequences in database:  164,201
  
Lambda     K      H
   0.317    0.135    0.388 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 55,679,322
Number of Sequences: 164201
Number of extensions: 2444191
Number of successful extensions: 7251
Number of sequences better than 10.0: 23
Number of HSP's better than 10.0 without gapping: 5
Number of HSP's successfully gapped in prelim test: 18
Number of HSP's that attempted gapping in prelim test: 7212
Number of HSP's gapped (non-prelim): 47
length of query: 468
length of database: 59,974,054
effective HSP length: 114
effective length of query: 354
effective length of database: 41,255,140
effective search space: 14604319560
effective search space used: 14604319560
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 68 (30.8 bits)