BLASTP 2.2.2 [Dec-14-2001]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= AC146331.10 + phase: 0 
         (485 letters)

Database: sprot 
           164,201 sequences; 59,974,054 total letters

Searching..................................................done

                                                                   Score     E
Sequences producing significant alignments:                        (bits)  Value

ABG2_HUMAN (Q9UNQ0) ATP-binding cassette, sub-family G, member 2...   234  5e-61
YPC3_CAEEL (Q11180) Putative ABC transporter C05D10.3 in chromos...   220  7e-57
WHIT_ANOGA (Q27256) White protein                                     207  6e-53
WHIT_CERCA (Q17320) White protein                                     205  2e-52
ABG1_HUMAN (P45844) ATP-binding cassette, sub-family G, member 1...   204  4e-52
ABG8_HUMAN (Q9H221) ATP-binding cassette, sub-family G, member 8...   204  5e-52
WHIT_DROME (P10090) White protein                                     200  6e-51
ABG8_RAT (P58428) ATP-binding cassette, sub-family G, member 8 (...   199  1e-50
ABG8_MOUSE (Q9DBM0) ATP-binding cassette, sub-family G, member 8...   198  2e-50
WHIT_LUCCU (Q05360) White protein                                     198  3e-50
WHIT_ANOAL (Q16928) White protein                                     194  3e-49
ADP1_YEAST (P25371) Probable ATP-dependent permease precursor         191  3e-48
SCRT_DROME (P45843) Scarlet protein                                   191  5e-48
ABG5_HUMAN (Q9H222) ATP-binding cassette, sub-family G, member 5...   174  5e-43
ABG5_RAT (Q99PE7) ATP-binding cassette, sub-family G, member 5 (...   172  1e-42
YOH5_YEAST (Q08234) Probable ATP-dependent transporter YOL074C/Y...   167  4e-41
ABG5_MOUSE (Q99PE8) ATP-binding cassette, sub-family G, member 5...   166  2e-40
ABG3_MOUSE (Q99P81) ATP-binding cassette, sub-family G, member 3      157  4e-38
YQ5C_CAEEL (Q09466) Putative ABC transporter C16C10.12 in chromo...   155  2e-37
CGR1_CANGA (O74208) ATP-binding cassette transporter CGR1 (Pleom...   154  5e-37

>ABG2_HUMAN (Q9UNQ0) ATP-binding cassette, sub-family G, member 2
           (Placenta-specific ATP-binding cassette transporter)
           (Breast cancer resistance protein)
          Length = 655

 Score =  234 bits (596), Expect = 5e-61
 Identities = 157/499 (31%), Positives = 256/499 (50%), Gaps = 37/499 (7%)

Query: 1   MTGNVLLNGKKKIPDYGFVA-YVTQEDVLLGTLTVKETIAYSAHLRLPSTMSKEEVSSII 59
           ++G+VL+NG  +  ++   + YV Q+DV++GTLTV+E + +SA LRL +TM+  E +  I
Sbjct: 102 LSGDVLINGAPRPANFKCNSGYVVQDDVVMGTLTVRENLQFSAALRLATTMTNHEKNERI 161

Query: 60  DGTIIEMGLQDCADRLIGNWHLRGISGGERKRTSIALEILTKPRLLFLDEPTCGLDSASA 119
           +  I E+GL   AD  +G   +RG+SGGERKRTSI +E++T P +LFLDEPT GLDS++A
Sbjct: 162 NRVIEELGLDKVADSKVGTQFIRGVSGGERKRTSIGMELITDPSILFLDEPTTGLDSSTA 221

Query: 120 FFVVQTLRNIAHDGRTVISSIHQPNSEVFALFDDLFLLARGETVYFGEAKMAIEFFAEAG 179
             V+  L+ ++  GRT+I SIHQP   +F LFD L LLA G  ++ G A+ A+ +F  AG
Sbjct: 222 NAVLLLLKRMSKQGRTIIFSIHQPRYSIFKLFDSLTLLASGRLMFHGPAQEALGYFESAG 281

Query: 180 FPCPRKRNPSDHFLRCINSDFDVVTATLKGSQRIHDV--PNSADPFMNLATAQIKSMLVE 237
           + C    NP+D FL  IN D   V    +   +  ++  P+  D         +   L E
Sbjct: 282 YHCEAYNNPADFFLDIINGDSTAVALNREEDFKATEIIEPSKQD-------KPLIEKLAE 334

Query: 238 RFKRSTYARRVKYNIQEQSTNEGIETETNY---GSQASWWKQLSTLTRRSFVNMCRDIGY 294
            +  S++ +  K  + + S  E  +  T +       S+  QL  +++RSF N+  +   
Sbjct: 335 IYVNSSFYKETKAELHQLSGGEKKKKITVFKEISYTTSFCHQLRWVSKRSFKNLLGNPQA 394

Query: 295 YWLRIIINIIVSICVGTLYFDVGYSYTSILARGACGAFVTGFMTTISIGSLPSVIEEMKV 354
              +II+ +++ + +G +YF +    T I  R     F+T      S+ ++   + E K+
Sbjct: 395 SIAQIIVTVVLGLVIGAIYFGLKNDSTGIQNRAGVLFFLTTNQCFSSVSAVELFVVEKKL 454

Query: 355 FYRERMNGYYGVAAYILANFISS-FPFLVVIALTSCTITYNMVKFRPGFIHYVFFTLNVY 413
           F  E ++GYY V++Y L   +S   P  ++ ++    I Y M+  +P      FF     
Sbjct: 455 FIHEYISGYYRVSSYFLGKLLSDLLPMRMLPSIIFTCIVYFMLGLKPK--ADAFF----- 507

Query: 414 GCLSVIESIMMVVASLVPNFLMGIVTGAGIIGI-----------MMMSSGFFRLLSDLPK 462
               V+   +M+VA    +  + I  G  ++ +           MM+ SG    L+ +  
Sbjct: 508 ----VMMFTLMMVAYSASSMALAIAAGQSVVSVATLLMTICFVFMMIFSGLLVNLTTIAS 563

Query: 463 -VVWRYPISYISYGAWATQ 480
            + W    S   YG  A Q
Sbjct: 564 WLSWLQYFSIPRYGFTALQ 582


>YPC3_CAEEL (Q11180) Putative ABC transporter C05D10.3 in chromosome
           III
          Length = 598

 Score =  220 bits (560), Expect = 7e-57
 Identities = 148/482 (30%), Positives = 241/482 (49%), Gaps = 23/482 (4%)

Query: 3   GNVLLNGKK----KIPDYGFVAYVTQEDVLLGTLTVKETIAYSAHLRLPSTM-SKEEVSS 57
           G++L++G++    KI +    A+V Q D+ +GT+T +E + + A LR+     S  E   
Sbjct: 52  GSILIDGRRANKWKIREMS--AFVQQHDMFVGTMTAREHLQFMARLRMGDQYYSDHERQL 109

Query: 58  IIDGTIIEMGLQDCADRLIGNWH-LRGISGGERKRTSIALEILTKPRLLFLDEPTCGLDS 116
            ++  + +MGL+ CAD +IG  + L+G+S GE+KR S A EILT P++LF DEPT GLD+
Sbjct: 110 RVEQVLTQMGLKKCADTVIGIPNQLKGLSCGEKKRLSFASEILTCPKILFCDEPTSGLDA 169

Query: 117 ASAFFVVQTLRNIAHDGRTVISSIHQPNSEVFALFDDLFLLARGETVYFGEAKMAIEFFA 176
             A  VVQ LR++A +G TVI +IHQP+S V++LF+++ L+A G  +Y G    A+  F 
Sbjct: 170 FMAGHVVQALRSLADNGMTVIITIHQPSSHVYSLFNNVCLMACGRVIYLGPGDQAVPLFE 229

Query: 177 EAGFPCPRKRNPSDHFLRCINSDFDVVTATLKGSQRIHDVPNSADPFMN-LATAQIKSML 235
           + G+PCP   NP+DH +R +         ++K   +I     S D   + LA      + 
Sbjct: 230 KCGYPCPAYYNPADHLIRTLAVIDSDRATSMKTISKIRQGFLSTDLGQSVLAIGNANKLR 289

Query: 236 VERFKRSTYARRVKYNIQEQSTNEGIETETNYGSQASWWKQLSTLTRRSFVNMCRDIGYY 295
              F            +    T+E  +T  N    AS+W Q   L  RS++ + RD    
Sbjct: 290 AASF------------VTGSDTSEKTKTFFNQDYNASFWTQFLALFWRSWLTVIRDPNLL 337

Query: 296 WLRIIINIIVSICVGTLYFDVGYSYTSILA-RGACGAFVTGFMTTISIGSLPSVIEEMKV 354
            +R++  +I +   G ++F    +  +I++  G     +      +   ++P +  E+ +
Sbjct: 338 SVRLLQILITAFITGIVFFQTPVTPATIISINGIMFNHIRNMNFMLQFPNVPVITAELPI 397

Query: 355 FYRERMNGYYGVAAYILANFISSFPFLVVIALTSCTITYNMVKFRPGFIHYVFFTLNVYG 414
             RE  NG Y  +AY LA  I+  P  +++ +   TI Y M    P F +Y F +L    
Sbjct: 398 VLRENANGVYRTSAYFLAKNIAELPQYIILPILYNTIVYWMSGLYPNFWNYCFASLVTIL 457

Query: 415 CLSVIESIMMVVASLVPNFLMGIVTGAGIIGIMMMSSGFFRLLSDLPKVV-WRYPISYIS 473
             +V  SI   VA++  N  + +      +  +M   GFF     +P    W   +SY  
Sbjct: 458 ITNVAISISYAVATIFANTDVAMTILPIFVVPIMAFGGFFITFDAIPSYFKWLSSLSYFK 517

Query: 474 YG 475
           YG
Sbjct: 518 YG 519


>WHIT_ANOGA (Q27256) White protein
          Length = 695

 Score =  207 bits (526), Expect = 6e-53
 Identities = 136/470 (28%), Positives = 241/470 (50%), Gaps = 29/470 (6%)

Query: 20  AYVTQEDVLLGTLTVKETIAYSAHLRL----PSTMSKEEVSSIIDGTIIEMGLQDCADRL 75
           AYV Q+D+ + +LT +E + + A LR+    P+++ +  V  ++     E+ L  CAD +
Sbjct: 179 AYVQQDDLFIPSLTTREHLLFQAMLRMGRDVPASVKQHRVQEVLQ----ELSLVKCADTI 234

Query: 76  IGN-WHLRGISGGERKRTSIALEILTKPRLLFLDEPTCGLDSASAFFVVQTLRNIAHDGR 134
           IG    ++G+SGGERKR + A E LT P LL  DEPT GLDS  A  V+Q L+ +A  G+
Sbjct: 235 IGAPGRIKGLSGGERKRLAFASETLTDPHLLLCDEPTSGLDSFMAHSVLQVLKGMAMKGK 294

Query: 135 TVISSIHQPNSEVFALFDDLFLLARGETVYFGEAKMAIEFFAEAGFPCPRKRNPSDHFLR 194
           T+I +IHQP+SE++ LFD + L+A G   + G    + EFF++ G PCP   NP+D +++
Sbjct: 295 TIILTIHQPSSELYCLFDKILLVAEGRVAFLGSPYQSAEFFSQLGIPCPPNYNPADFYVQ 354

Query: 195 CINSDFDVVTATLKGSQRIHDVPNSADPFMNLATAQIKSMLVERFKRSTYARRVKYNIQE 254
            +        A  K ++    +    D F   A + I   ++E    +       Y +Q+
Sbjct: 355 ML------AIAPAKEAECRDMIKKICDSF---AVSPIAREVLETASVAGKGMDEPYMLQQ 405

Query: 255 QSTNEGIETETNYGSQASWWKQLSTLTRRSFVNMCRDIGYYWLRIIINIIVSICVGTLYF 314
                 +E   + G ++SWW Q   +  RS++++ +D     +R++   +V+  +G++YF
Sbjct: 406 ------VEGVGSTGYRSSWWTQFYCILWRSWLSVLKDPMLVKVRLLQTAMVATLIGSIYF 459

Query: 315 DVGYSYTSIL-ARGACGAFVTGFMTTISIGSLPSVIE-EMKVFYRERMNGYYGVAAYILA 372
                   ++   G+   F+T  MT  ++ ++ +V   E+ VF RE+ +  Y V  Y L 
Sbjct: 460 GQVLDQDGVMNINGSLFLFLTN-MTFQNVFAVINVFSAELPVFLREKRSRLYRVDTYFLG 518

Query: 373 NFISSFPFLVVIALTSCTITYNMVKFRPGFIHYVFFTLNVYGCLSVIESIMMVVASLVPN 432
             I+  P  + +     +ITY M+  R G  HY+     V    +V  S   +++    +
Sbjct: 519 KTIAELPLFIAVPFVFTSITYPMIGLRTGATHYLTTLFIVTLVANVSTSFGYLISCASSS 578

Query: 433 FLMGIVTGAGIIGIMMMSSGFFRLLSDLPKVVWRYPISYISYGAWATQVI 482
             M +  G  ++   ++  GFF   + +P   ++Y +SY+S+  +A + +
Sbjct: 579 ISMALSVGPPVVIPFLIFGGFFLNSASVP-AYFKY-LSYLSWFRYANEAL 626


>WHIT_CERCA (Q17320) White protein
          Length = 679

 Score =  205 bits (522), Expect = 2e-52
 Identities = 132/465 (28%), Positives = 230/465 (49%), Gaps = 28/465 (6%)

Query: 20  AYVTQEDVLLGTLTVKETIAYSAHLRLPSTMSKEEVSSIIDGTIIEMGLQDCADRLIG-N 78
           AYV Q+D+ +G+LT +E + + A +R+P  M++++    +D  I ++ L  C + LIG  
Sbjct: 167 AYVQQDDLFIGSLTAREHLIFQAMVRMPRHMTQKQKVQRVDQVIQDLSLGKCQNTLIGVP 226

Query: 79  WHLRGISGGERKRTSIALEILTKPRLLFLDEPTCGLDSASAFFVVQTLRNIAHDGRTVIS 138
             ++G+SGGERKR + A E LT P LL  DEPT GLDS  A  VVQ L+ ++  G+TVI 
Sbjct: 227 GRVKGLSGGERKRLAFASEALTDPPLLICDEPTSGLDSFMAHSVVQVLKKLSQKGKTVIL 286

Query: 139 SIHQPNSEVFALFDDLFLLARGETVYFGEAKMAIEFFAEAGFPCPRKRNPSDHFLRCINS 198
           +IHQP+SE+F LFD + L+A G   + G    A++FF+  G  CP    P+D +++    
Sbjct: 287 TIHQPSSELFELFDKILLMAEGRVAFLGTPGEAVDFFSYIGATCPTNYTPADFYVQ---- 342

Query: 199 DFDVVTATLKGSQRIHDVPNSADPFMNLATAQIKSMLVERFKRSTYARRVKYNIQE--QS 256
               V A + G +              + +    + + + F     +R ++ N Q+  +S
Sbjct: 343 ----VLAVVPGRE--------------VESRDRVAKICDNFAVGKVSREMEQNFQKLVKS 384

Query: 257 TNEGIETETNYGSQASWWKQLSTLTRRSFVNMCRDIGYYWLRIIINIIVSICVGTLYFDV 316
              G E E  Y  +ASW+ Q   +  RS++++ ++     +R++   +V++ +G ++   
Sbjct: 385 NGFGKEDENEYTYKASWFMQFRAVLWRSWLSVLKEPLLVKVRLLQTTMVAVLIGLIFLGQ 444

Query: 317 GYSYTSIL-ARGACGAFVTGFMTTISIGSLPSVIEEMKVFYRERMNGYYGVAAYILANFI 375
             +   ++   GA   F+T      S  ++     E+ VF RE  +  Y    Y L   I
Sbjct: 445 QLTQVGVMNINGAIFLFLTNMTFQNSFATITVFTTELPVFMRETRSRLYRCDTYFLGKTI 504

Query: 376 SSFPFLVVIALTSCTITYNMVKFRPGFIHYVFFTLNVYGCLSVIESIMMVVASLVPNFLM 435
           +  P  +V+      I Y ++  RPG  H+      V    +V  S   +++    +  M
Sbjct: 505 AELPLFLVVPFLFTAIAYPLIGLRPGVDHFFTALALVTLVANVSTSFGYLISCACSSTSM 564

Query: 436 GIVTGAGIIGIMMMSSGFFRLLSDLPKVVWRYPISYISYGAWATQ 480
            +  G  +I   ++  GFF     +P  V+   +SY+S+  +A +
Sbjct: 565 ALSVGPPVIIPFLLFGGFFLNSGSVP--VYFKWLSYLSWFRYANE 607


>ABG1_HUMAN (P45844) ATP-binding cassette, sub-family G, member 1
           (White protein homolog) (ATP-binding cassette
           transporter 8)
          Length = 678

 Score =  204 bits (519), Expect = 4e-52
 Identities = 142/483 (29%), Positives = 248/483 (50%), Gaps = 24/483 (4%)

Query: 1   MTGNVLLNG-KKKIPDYGFVA-YVTQEDVLLGTLTVKETIAYSAHLRLPSTMSKEEVSSI 58
           M G VL+NG  + +  +  V+ Y+ Q+D+LL  LTV+E +  SAHL+L      E    +
Sbjct: 139 MKGAVLINGLPRDLRCFRKVSCYIMQDDMLLPHLTVQEAMMVSAHLKLQE--KDEGRREM 196

Query: 59  IDGTIIEMGLQDCADRLIGNWHLRGISGGERKRTSIALEILTKPRLLFLDEPTCGLDSAS 118
           +   +  +GL  CA+   G+     +SGG+RKR +IALE++  P ++F DEPT GLDSAS
Sbjct: 197 VKEILTALGLLSCANTRTGS-----LSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSAS 251

Query: 119 AFFVVQTLRNIAHDGRTVISSIHQPNSEVFALFDDLFLLARGETVYFGEAKMAIEFFAEA 178
            F VV  ++ +A  GR++I +IHQP++++F LFD L++L++G+ VY G+    + +  + 
Sbjct: 252 CFQVVSLMKGLAQGGRSIICTIHQPSAKLFELFDQLYVLSQGQCVYRGKVCNLVPYLRDL 311

Query: 179 GFPCPRKRNPSDHFLRCINSDFDVVTATLKGSQRIHDVPNSADPFMNL-ATAQIKSMLVE 237
           G  CP   NP+D  +   + ++    + L   + + +    +D   +L   A++   L  
Sbjct: 312 GLNCPTYHNPADFVMEVASGEYGDQNSRL--VRAVREGMCDSDHKRDLGGDAEVNPFLWH 369

Query: 238 R-FKRSTYARRVKYNIQEQSTNEGIETETNYGSQASWWKQLSTLTRRSFVNMCRDIGYYW 296
           R  +     +R+K   ++ S+ EG      +   AS   Q   L +R+F+++ RD     
Sbjct: 370 RPSEEVKQTKRLKGLRKDSSSMEGC-----HSFSASCLTQFCILFKRTFLSIMRDSVLTH 424

Query: 297 LRIIINIIVSICVGTLYFDVGYSYTSILARGACGAFVTGFMTTISIGSLPSVIE---EMK 353
           LRI  +I + + +G LY  +G     +L+      F   F+   ++  +P+V+    EM 
Sbjct: 425 LRITSHIGIGLLIGLLYLGIGNEAKKVLSNSGFLFFSMLFLMFAAL--MPTVLTFPLEMG 482

Query: 354 VFYRERMNGYYGVAAYILANFISSFPFLVVIALTSCTITYNMVKFRPGFIHYVFFTLNVY 413
           VF RE +N +Y + AY LA  ++  PF ++  +  C+I Y M       + +V F     
Sbjct: 483 VFLREHLNYWYSLKAYYLAKTMADVPFQIMFPVAYCSIVYWMTSQPSDAVRFVLFAALGT 542

Query: 414 GCLSVIESIMMVVASLVPNFLMGIVTGAGIIGIMMMSSGFFRLLSDLPKVV-WRYPISYI 472
               V +S+ +++ +   +  +    G      +++ SGFF     +P  + W   ISY+
Sbjct: 543 MTSLVAQSLGLLIGAASTSLQVATFVGPVTAIPVLLFSGFFVSFDTIPTYLQWMSYISYV 602

Query: 473 SYG 475
            YG
Sbjct: 603 RYG 605


>ABG8_HUMAN (Q9H221) ATP-binding cassette, sub-family G, member 8
           (Sterolin-2)
          Length = 673

 Score =  204 bits (518), Expect = 5e-52
 Identities = 141/488 (28%), Positives = 230/488 (46%), Gaps = 30/488 (6%)

Query: 2   TGNVLLNGKKKIPDY--GFVAYVTQEDVLLGTLTVKETIAYSAHLRLPSTMSKEEVSSII 59
           +G + +NG+   P      VA+V Q + LL  LTV+ET+A+ A +RLP T S+ +    +
Sbjct: 129 SGQIWINGQPSSPQLVRKCVAHVRQHNQLLPNLTVRETLAFIAQMRLPRTFSQAQRDKRV 188

Query: 60  DGTIIEMGLQDCADRLIGNWHLRGISGGERKRTSIALEILTKPRLLFLDEPTCGLDSASA 119
           +  I E+ L+ CAD  +GN ++RG+SGGER+R SI +++L  P +L LDEPT GLDS +A
Sbjct: 189 EDVIAELRLRQCADTRVGNMYVRGLSGGERRRVSIGVQLLWNPGILILDEPTSGLDSFTA 248

Query: 120 FFVVQTLRNIAHDGRTVISSIHQPNSEVFALFDDLFLLARGETVYFGEAKMAIEFFAEAG 179
             +V+TL  +A   R V+ S+HQP S++F LFD + L+  G  +Y G A+  +++F   G
Sbjct: 249 HNLVKTLSRLAKGNRLVLISLHQPRSDIFRLFDLVLLMTSGTPIYLGAAQHMVQYFTAIG 308

Query: 180 FPCPRKRNPSDHFLRCINSDFDVVTATLKGSQRIHDVPNSADPFMNLATAQIKSMLVERF 239
           +PCPR  NP+D ++       D+ +   +  ++       A     L   +++ +    +
Sbjct: 309 YPCPRYSNPADFYV-------DLTSIDRRSREQELATREKAQSLAALFLEKVRDLDDFLW 361

Query: 240 KRSTYARRVKYNIQEQSTNEGIETETNYGSQASWWK------QLSTLTRRSFVNMCRDIG 293
           K  T       ++ E +  E   T  +     S  K      Q +TL RR   N  RD+ 
Sbjct: 362 KAET------KDLDEDTCVESSVTPLDTNCLPSPTKMPGAVQQFTTLIRRQISNDFRDLP 415

Query: 294 YYWLRIIINIIVSICVGTLYFDVGYSYTSILARGACGAFVTGFMT--TISIGSLPSVIEE 351
              +      ++S+ +G LYF  G    S +   A   F+ G +    + +  +     E
Sbjct: 416 TLLIHGAEACLMSMTIGFLYFGHGSIQLSFMDTAAL-LFMIGALIPFNVILDVISKCYSE 474

Query: 352 MKVFYRERMNGYYGVAAYILANFISSFPFLVVIALTSCTITYNMVKFRPGFIHYVFFTLN 411
             + Y E  +G Y    Y  A  +   P      +     TY +   RPG   ++   L 
Sbjct: 475 RAMLYYELEDGLYTTGPYFFAKILGELPEHCAYIIIYGMPTYWLANLRPGLQPFLLHFLL 534

Query: 412 VYGCLSVIESIMMVVASLVPNFLMGIVTGAGIIGIMMMSSGFFRLLSDLPKVVWRYP--I 469
           V+  +     + +  A+L+P F M       +     ++ GF   LS L    W  P  I
Sbjct: 535 VWLVVFCCRIMALAAAALLPTFHMASFFSNALYNSFYLAGGFMINLSSL----WTVPAWI 590

Query: 470 SYISYGAW 477
           S +S+  W
Sbjct: 591 SKVSFLRW 598


>WHIT_DROME (P10090) White protein
          Length = 687

 Score =  200 bits (509), Expect = 6e-51
 Identities = 130/464 (28%), Positives = 229/464 (49%), Gaps = 27/464 (5%)

Query: 20  AYVTQEDVLLGTLTVKETIAYSAHLRLPSTMSKEEVSSIIDGTIIEMGLQDCADRLIG-N 78
           AYV Q+D+ +G+LT +E + + A +R+P  ++  +  + +D  I E+ L  C   +IG  
Sbjct: 176 AYVQQDDLFIGSLTAREHLIFQAMVRMPRHLTYRQRVARVDQVIQELSLSKCQHTIIGVP 235

Query: 79  WHLRGISGGERKRTSIALEILTKPRLLFLDEPTCGLDSASAFFVVQTLRNIAHDGRTVIS 138
             ++G+SGGERKR + A E LT P LL  DEPT GLDS +A  VVQ L+ ++  G+TVI 
Sbjct: 236 GRVKGLSGGERKRLAFASEALTDPPLLICDEPTSGLDSFTAHSVVQVLKKLSQKGKTVIL 295

Query: 139 SIHQPNSEVFALFDDLFLLARGETVYFGEAKMAIEFFAEAGFPCPRKRNPSDHFLRCINS 198
           +IHQP+SE+F LFD + L+A G   + G    A++FF+  G  CP   NP+D +++    
Sbjct: 296 TIHQPSSELFELFDKILLMAEGRVAFLGTPSEAVDFFSYVGAQCPTNYNPADFYVQ---- 351

Query: 199 DFDVVTATLKGSQRIHDVPNSADPFMNLATAQIKSMLVERFKRSTYARRVKYNIQEQSTN 258
               V A + G +              + +    + + + F  S  AR ++  +  ++  
Sbjct: 352 ----VLAVVPGRE--------------IESRDRIAKICDNFAISKVARDMEQLLATKNLE 393

Query: 259 EGIE-TETNYGSQASWWKQLSTLTRRSFVNMCRDIGYYWLRIIINIIVSICVGTLYFDVG 317
           + +E  E  Y  +A+W+ Q   +  RS++++ ++     +R+I   +V+I +G ++    
Sbjct: 394 KPLEQPENGYTYKATWFMQFRAVLWRSWLSVLKEPLLVKVRLIQTTMVAILIGLIFLGQQ 453

Query: 318 YSYTSIL-ARGACGAFVTGFMTTISIGSLPSVIEEMKVFYRERMNGYYGVAAYILANFIS 376
            +   ++   GA   F+T         ++     E+ VF RE  +  Y    Y L   I+
Sbjct: 454 LTQVGVMNINGAIFLFLTNMTFQNVFATINVFTSELPVFMREARSRLYRCDTYFLGKTIA 513

Query: 377 SFPFLVVIALTSCTITYNMVKFRPGFIHYVFFTLNVYGCLSVIESIMMVVASLVPNFLMG 436
             P  + + L    I Y M+  R G +H+      V    +V  S   +++    +  M 
Sbjct: 514 ELPLFLTVPLVFTAIAYPMIGLRAGVLHFFNCLALVTLVANVSTSFGYLISCASSSTSMA 573

Query: 437 IVTGAGIIGIMMMSSGFFRLLSDLPKVVWRYPISYISYGAWATQ 480
           +  G  +I   ++  GFF     +P  V+   +SY+S+  +A +
Sbjct: 574 LSVGPPVIIPFLLFGGFFLNSGSVP--VYLKWLSYLSWFRYANE 615


>ABG8_RAT (P58428) ATP-binding cassette, sub-family G, member 8
           (Sterolin-2)
          Length = 694

 Score =  199 bits (507), Expect = 1e-50
 Identities = 142/496 (28%), Positives = 242/496 (48%), Gaps = 47/496 (9%)

Query: 2   TGNVLLNGKKKIPDY--GFVAYVTQEDVLLGTLTVKETIAYSAHLRLPSTMSKEEVSSII 59
           +G + +NG+   P      VA+V Q+D LL  LTV+ET+ + A +RLP T S+ +    +
Sbjct: 151 SGQIWINGQPSTPQLIQKCVAHVRQQDQLLPNLTVRETLTFIAQMRLPKTFSQAQRDKRV 210

Query: 60  DGTIIEMGLQDCADRLIGNWHLRGISGGERKRTSIALEILTKPRLLFLDEPTCGLDSASA 119
           +  I E+ L+ CA+  +GN ++RG+SGGER+R SI +++L  P +L LDEPT GLDS +A
Sbjct: 211 EDVIAELRLRQCANTRVGNTYVRGVSGGERRRVSIGVQLLWNPGILILDEPTSGLDSFTA 270

Query: 120 FFVVQTLRNIAHDGRTVISSIHQPNSEVFALFDDLFLLARGETVYFGEAKMAIEFFAEAG 179
             +V+TL  +A   R V+ S+HQP S++F LFD + L+  G  +Y G A+  +++F   G
Sbjct: 271 HNLVRTLSRLAKGNRLVLISLHQPRSDIFRLFDLVLLMTSGTPIYLGVAQHMVQYFTSIG 330

Query: 180 FPCPRKRNPSDHFLRCINSD---FDVVTATLKGSQRIH----DVPNSADPFMNLATAQIK 232
           +PCPR  NP+D ++   + D    +   AT++ ++ +     +     D F  L  A+ K
Sbjct: 331 YPCPRYSNPADFYVDLTSIDRRSKEQEVATMEKARLLAALFLEKVQGFDDF--LWKAEAK 388

Query: 233 SMLVERFKRSTYARRVKYNIQEQSTNEGIETETNYGSQA---SWWKQLSTLTRRSFVNMC 289
           S+        TYA            ++ +  +TN G+ A      +Q +TL RR   N  
Sbjct: 389 SL-----DTGTYA-----------VSQTLTQDTNCGTAAELPGMIQQFTTLIRRQISNDF 432

Query: 290 RDIGYYWLRIIINIIVSICVGTLYFDVGYSYTSILARGACGAFVTGFMT--TISIGSLPS 347
           RD+   ++      ++S+ +G LY+       S +   A   F+ G +    + +  +  
Sbjct: 433 RDLPTLFIHGAEACLMSLIIGFLYYGHADKPLSFMDMAAL-LFMIGALIPFNVILDVVSK 491

Query: 348 VIEEMKVFYRERMNGYYGVAAYILANFISSFPFLVVIALTSCTITYNMVKFRPG----FI 403
              E  + Y E  +G Y    Y  A  +   P      +      Y +   RPG     +
Sbjct: 492 CHSERSLLYYELEDGLYTAGPYFFAKVLGELPEHCAYVIIYGMPIYWLTNLRPGPELFLL 551

Query: 404 HYVFFTLNVYGCLSVIESIMMVVASLVPNFLMGIVTGAGIIGIMMMSSGFFRLLSDLPKV 463
           H++   L V+ C     ++ +  ++++P F M       +     +++GF   L++L   
Sbjct: 552 HFMLLWLVVFCC----RTMALAASAMLPTFHMSSFCCNALYNSFYLTAGFMINLNNL--- 604

Query: 464 VWRYP--ISYISYGAW 477
            W  P  IS +S+  W
Sbjct: 605 -WIVPAWISKMSFLRW 619


>ABG8_MOUSE (Q9DBM0) ATP-binding cassette, sub-family G, member 8
           (Sterolin-2)
          Length = 673

 Score =  198 bits (504), Expect = 2e-50
 Identities = 137/489 (28%), Positives = 231/489 (47%), Gaps = 33/489 (6%)

Query: 2   TGNVLLNGKKKIPDY--GFVAYVTQEDVLLGTLTVKETIAYSAHLRLPSTMSKEEVSSII 59
           +G + +NG+   P      VA+V Q D LL  LTV+ET+A+ A +RLP T S+ +    +
Sbjct: 130 SGQIWINGQPSTPQLVRKCVAHVRQHDQLLPNLTVRETLAFIAQMRLPRTFSQAQRDKRV 189

Query: 60  DGTIIEMGLQDCADRLIGNWHLRGISGGERKRTSIALEILTKPRLLFLDEPTCGLDSASA 119
           +  I E+ L+ CA+  +GN ++RG+SGGER+R SI +++L  P +L LDEPT GLDS +A
Sbjct: 190 EDVIAELRLRQCANTRVGNTYVRGVSGGERRRVSIGVQLLWNPGILILDEPTSGLDSFTA 249

Query: 120 FFVVQTLRNIAHDGRTVISSIHQPNSEVFALFDDLFLLARGETVYFGEAKMAIEFFAEAG 179
             +V TL  +A   R V+ S+HQP S++F LFD + L+  G  +Y G A+  +++F   G
Sbjct: 250 HNLVTTLSRLAKGNRLVLISLHQPRSDIFRLFDLVLLMTSGTPIYLGAAQQMVQYFTSIG 309

Query: 180 FPCPRKRNPSDHFLRCINSDFDVVTATLKGSQRIHDVPNSADPFMNLATAQIKSMLVERF 239
            PCPR  NP+D ++       D+ +   +  +R       A     L   +++      +
Sbjct: 310 HPCPRYSNPADFYV-------DLTSIDRRSKEREVATVEKAQSLAALFLEKVQGFDDFLW 362

Query: 240 KRSTYARRVKYNIQEQSTNEGIETETNYGSQA---SWWKQLSTLTRRSFVNMCRDIGYYW 296
           K    A   + N    + +  +  +T+ G+        +Q STL RR   N  RD+    
Sbjct: 363 K----AEAKELNTSTHTVSLTLTQDTDCGTAVELPGMIEQFSTLIRRQISNDFRDLPTLL 418

Query: 297 LRIIINIIVSICVGTLYFDVGYSYTSILARGACGAFVTGFMT--TISIGSLPSVIEEMKV 354
           +      ++S+ +G LY+  G    S +   A   F+ G +    + +  +     E  +
Sbjct: 419 IHGSEACLMSLIIGFLYYGHGAKQLSFMDTAAL-LFMIGALIPFNVILDVVSKCHSERSM 477

Query: 355 FYRERMNGYYGVAAYILANFISSFPFLVVIALTSCTITYNMVKFRP----GFIHYVFFTL 410
            Y E  +G Y    Y  A  +   P      +      Y +   RP      +H++   L
Sbjct: 478 LYYELEDGLYTAGPYFFAKILGELPEHCAYVIIYAMPIYWLTNLRPVPELFLLHFLLVWL 537

Query: 411 NVYGCLSVIESIMMVVASLVPNFLMGIVTGAGIIGIMMMSSGFFRLLSDLPKVVWRYP-- 468
            V+ C     ++ +  ++++P F M       +     +++GF   L +L    W  P  
Sbjct: 538 VVFCC----RTMALAASAMLPTFHMSSFFCNALYNSFYLTAGFMINLDNL----WIVPAW 589

Query: 469 ISYISYGAW 477
           IS +S+  W
Sbjct: 590 ISKLSFLRW 598


>WHIT_LUCCU (Q05360) White protein
          Length = 677

 Score =  198 bits (503), Expect = 3e-50
 Identities = 133/467 (28%), Positives = 236/467 (50%), Gaps = 31/467 (6%)

Query: 20  AYVTQEDVLLGTLTVKETIAYSAHLRLPSTMSKEEVSSIIDGTIIEMGLQDCADRLIG-N 78
           AYV Q+D+ +G+LT +E + + A +R+P TM++++    +D  I ++ L  C + +IG  
Sbjct: 165 AYVQQDDLFIGSLTAREHLIFQATVRMPRTMTQKQKLQRVDQVIQDLSLIKCQNTIIGVP 224

Query: 79  WHLRGISGGERKRTSIALEILTKPRLLFLDEPTCGLDSASAFFVVQTLRNIAHDGRTVIS 138
             ++G+SGGERKR + A E LT P LL  DEPT GLDS  A  VVQ L+ ++  G+TVI 
Sbjct: 225 GRVKGLSGGERKRLAFASEALTDPPLLICDEPTSGLDSFMAASVVQVLKKLSQRGKTVIL 284

Query: 139 SIHQPNSEVFALFDDLFLLARGETVYFGEAKMAIEFFAEAGFPCPRKRNPSDHFLRCINS 198
           +IHQP+SE+F LFD + L+A G   + G    A++FF+  G  CP   NP+D +++    
Sbjct: 285 TIHQPSSELFELFDKILLMAEGRVAFLGTPVEAVDFFSFIGAQCPTNYNPADFYVQ---- 340

Query: 199 DFDVVTATLKGSQRIHDVPNSADPFMNLATAQIKSMLVERFKRSTYARRVKYNIQE-QST 257
               V A + G +              + +    S + + F     +R ++ N Q+  + 
Sbjct: 341 ----VLAVVPGRE--------------IESRDRISKICDNFAVGKVSREMEQNFQKIAAK 382

Query: 258 NEGI--ETETNYGSQASWWKQLSTLTRRSFVNMCRDIGYYWLRIIINIIVSICVGTLYFD 315
            +G+  + ET    +ASW+ Q   +  RS+++  ++     +R+I   +V++ +G ++ +
Sbjct: 383 TDGLQKDDETTILYKASWFTQFRAIMWRSWISTLKEPLLVKVRLIQTTMVAVLIGLIFLN 442

Query: 316 VGYSYTSIL-ARGACGAFVTGFMTTISIGSLPSVI-EEMKVFYRERMNGYYGVAAYILAN 373
              +   ++   GA   F+T  MT  ++ ++ +V   E+ VF RE  +  Y    Y L  
Sbjct: 443 QPMTQVGVMNINGAIFLFLTN-MTFQNVFAVINVFTSELPVFMRETRSRLYRCDTYFLGK 501

Query: 374 FISSFPFLVVIALTSCTITYNMVKFRPGFIHYVFFTLNVYGCLSVIESIMMVVASLVPNF 433
            ++  P  +V+      I Y M+  RPG  H++     V    +V  S   +++    + 
Sbjct: 502 TLAELPLFLVVPFLFIAIAYPMIGLRPGITHFLSALALVTLVANVSTSFGYLISCASTST 561

Query: 434 LMGIVTGAGIIGIMMMSSGFFRLLSDLPKVVWRYPISYISYGAWATQ 480
            M +  G  +    ++  G F     +P  V+   +SY S+  +A +
Sbjct: 562 SMALSVGPPLTIPFLLFGGVFLNSGSVP--VYFKWLSYFSWFRYANE 606


>WHIT_ANOAL (Q16928) White protein
          Length = 709

 Score =  194 bits (494), Expect = 3e-49
 Identities = 132/471 (28%), Positives = 239/471 (50%), Gaps = 21/471 (4%)

Query: 20  AYVTQEDVLLGTLTVKETIAYSAHLRLPSTMSKEEVSSI-IDGTIIEMGLQDCADRLIG- 77
           AYV Q+D+ + +LT KE + + A LR+   +    +    +D  + E+ L  CAD +IG 
Sbjct: 182 AYVQQDDLFIPSLTTKEHLMFQAMLRMGRDVPATPIKMHRVDEVLQELSLVKCADTIIGV 241

Query: 78  NWHLRGISGGERKRTSIALEILTKPRLLFLDEPTCGLDSASAFFVVQTLRNIAHDGRTVI 137
              ++G+SGGERKRT+   E LT P LL  DEPT  LDS  A  V+Q L+ +A  G+T+I
Sbjct: 242 AGRVKGLSGGERKRTAFRSETLTDPHLLLCDEPTSSLDSFMAQSVLQVLKGMAMKGKTII 301

Query: 138 SSIHQPNSEVFALFDDLFLLARGETVYFGEAKMAIEFFAEAGFPCPRKRNPSDHFLRCIN 197
            +IHQP+SE++ LFD + L+A G   + G    + +FF++ G PCP   NP+D +++ + 
Sbjct: 302 LTIHQPSSELYCLFDRILLVAEG-VAFLGSPYQSADFFSQLGIPCPPNYNPADFYVQML- 359

Query: 198 SDFDVVTATLKGSQRIHDVPNSADPFMNLATAQIKSMLVERFKRSTYARRVKYNIQEQST 257
                  A  K ++    +    D F   A + I   ++E   +      ++    + +T
Sbjct: 360 -----AIAPNKETECRETIKKICDSF---AVSPIARDIIETASQVNGDGGIELTRTKHTT 411

Query: 258 N----EGIETETNYGSQASWWKQLSTLTRRSFVNMCRDIGYYWLRIIINIIVSICVGTLY 313
           +    + +E   + G +ASWW Q   +  RS++++ +D     +R++   +V+  +G++Y
Sbjct: 412 DPYFLQPMEGVDSTGYRASWWTQFYCILWRSWLSVLKDPMLVKVRLLQTAMVASLIGSIY 471

Query: 314 FDVGYSYTSIL-ARGACGAFVTGFMTTISIGSLPSVIE-EMKVFYRERMNGYYGVAAYIL 371
           F        ++   G+   F+T  MT  ++ ++ +V   E+ VF RE+ +  Y V  Y L
Sbjct: 472 FGQVLDQDGVMNINGSLFLFLTN-MTFQNVFAVINVFSAELPVFLREKRSRLYRVDTYFL 530

Query: 372 ANFISSFPFLVVIALTSCTITYNMVKFRPGFIHYVFFTLNVYGCLSVIESIMMVVASLVP 431
              I+  P  + +     +ITY M+  +    HY+     V    +V  S   +++    
Sbjct: 531 GKTIAELPLFIAVPFVFTSITYPMIGLKAAISHYLTTLFIVTLVANVSTSFGYLISCASS 590

Query: 432 NFLMGIVTGAGIIGIMMMSSGFFRLLSDLPKVVWRYPISYISYGAWATQVI 482
           +  M +  G  ++   ++  GFF   + +P   ++Y +SY+S+  +A + +
Sbjct: 591 SISMALSVGPPVVIPFLIFGGFFLNSASVP-AYFKY-LSYLSWFRYANEAL 639


>ADP1_YEAST (P25371) Probable ATP-dependent permease precursor
          Length = 1049

 Score =  191 bits (486), Expect = 3e-48
 Identities = 140/432 (32%), Positives = 206/432 (47%), Gaps = 55/432 (12%)

Query: 19  VAYVTQEDVLLGTLTVKETIAYSAHLRLPSTMSKEEVSSIIDGTIIEMGLQDCADRLIGN 78
           + +V Q+D LL TLTV ET+  SA LRLP  +S E   + +   + E+ + D  DR+IGN
Sbjct: 465 IGFVDQDDFLLPTLTVFETVLNSALLRLPKALSFEAKKARVYKVLEELRIIDIKDRIIGN 524

Query: 79  WHLRGISGGERKRTSIALEILTKPRLLFLDEPTCGLDSASAFFVVQTLRNIAHD-GRTVI 137
              RGISGGE++R SIA E++T P +LFLDEPT GLD+++A  V++ L  ++ D  RT++
Sbjct: 525 EFDRGISGGEKRRVSIACELVTSPLVLFLDEPTSGLDASNANNVIECLVRLSSDYNRTLV 584

Query: 138 SSIHQPNSEVFALFDDLFLLARGETVYFGEAKMAIEFFAEAGFPCPRKRNPSDHFL---- 193
            SIHQP S +F LFD L LL++GE VY G AK   EF    G+ CP   N +D+ +    
Sbjct: 585 LSIHQPRSNIFYLFDKLVLLSKGEMVYSGNAKKVSEFLRNEGYICPDNYNIADYLIDITF 644

Query: 194 ---------RCIN-SDFDVVTATLKGSQRIHDVP-NSADPFMNLATAQIKS--------- 233
                    R  N SD +  T T      IH     S+D       A + +         
Sbjct: 645 EAGPQGKRRRIRNISDLEAGTDTNDIDNTIHQTTFTSSDGTTQREWAHLAAHRDEIRSLL 704

Query: 234 -----------------------MLVERFKRSTYARRVKYNIQEQSTNEGIETETNYG-- 268
                                  +L +++K S Y   +   I+E  +    E+    G  
Sbjct: 705 RDEEDVEGTDGRRGATEIDLNTKLLHDKYKDSVYYAELSQEIEEVLSEGDEESNVLNGDL 764

Query: 269 ----SQASWWKQLSTLTRRSFVNMCRDIGYYWLRIIINIIVSICVGTLYFDVGYSYTSIL 324
                 A + +QLS L  RSF NM R+        ++ I++S+ +GTLY++V    +   
Sbjct: 765 PTGQQSAGFLQQLSILNSRSFKNMYRNPKLLLGNYLLTILLSLFLGTLYYNVSNDISGFQ 824

Query: 325 ARGACGAFVTGFMTTISIGSLPSVIEEMKVFYRERMNGYYGVAAYILANFISS-FPFLVV 383
            R     F+  +   ++   L S   E  +F +ER N YY   AY ++  +S   P  VV
Sbjct: 825 NRMGLFFFILTYFGFVTFTGLSSFALERIIFIKERSNNYYSPLAYYISKIMSEVVPLRVV 884

Query: 384 IALTSCTITYNM 395
             +    I Y M
Sbjct: 885 PPILLSLIVYPM 896


>SCRT_DROME (P45843) Scarlet protein
          Length = 666

 Score =  191 bits (484), Expect = 5e-48
 Identities = 146/486 (30%), Positives = 235/486 (48%), Gaps = 59/486 (12%)

Query: 3   GNVLLNGKKKIP----DYGFVAYVTQEDVLLGTLTVKETIAYSAHLRLPSTMSKEEVSSI 58
           G++L+NG++  P    ++G   YV Q+D+ LG+++V E + + AHLRL   +SKEE   I
Sbjct: 133 GDILINGRRIGPFMHRNHG---YVYQDDLFLGSVSVLEHLNFMAHLRLDRRVSKEERRLI 189

Query: 59  IDGTIIEMGLQDCADRLIGNWHLRGI-SGGERKRTSIALEILTKPRLLFLDEPTCGLDSA 117
           I   +   GL   A   IG+   + + SGGERKR + A+E+L  P +LF DEPT GLDS 
Sbjct: 190 IKELLERTGLLSAAQTRIGSGDDKKVLSGGERKRLAFAVELLNNPVILFCDEPTTGLDSY 249

Query: 118 SAFFVVQTLRNIAHDGRTVISSIHQPNSEVFALFDDLFLLARGETVYFGEAKMAIEFFAE 177
           SA  +V TL  +A  G T++ +IHQP+S++F  F+++ LLA G   + G  + A+ FFA 
Sbjct: 250 SAQQLVATLYELAQKGTTILCTIHQPSSQLFDNFNNVMLLADGRVAFTGSPQHALSFFAN 309

Query: 178 AGFPCPRKRNPSDHFLRCINSDFDVVTATLKGSQRIHDVPNSADPFMNLATAQIKSMLVE 237
            G+ CP   NP+D  +  + +D     A+ + +Q +       D F   + A+ + MLV 
Sbjct: 310 HGYYCPEAYNPADFLIGVLATDPGYEQASQRSAQHL------CDQFAVSSAAKQRDMLV- 362

Query: 238 RFKRSTYARRVKYNIQ---EQSTNEGIETETNYGSQASWWKQLSTLTRRSFVNMCRDIGY 294
                        N++    QS N   +TE       +W+K+   +  R+ V + RD   
Sbjct: 363 -------------NLEIHMAQSGNFPFDTEVESFRGVAWYKRFHVVWLRAIVTLLRDPTI 409

Query: 295 YWLRIIINIIVSICVGTLYFDVGYSYTSILARGACGAFVTGFMTTISIGSLPSVI----E 350
            WLR I  I ++  +G  +   G +  S L   A    +   ++  +   + SV+    +
Sbjct: 410 QWLRFIQKIAMAFIIGACF--AGTTEPSQLGVQAVQGALFIMISENTYHPMYSVLNLFPQ 467

Query: 351 EMKVFYRERMNGYYGVAAYILANFISSFPFLVVIALTSCTITYNMVKFRPGFIHY----- 405
              +F RE  +G Y    Y  AN ++  P +++  L    I Y +   R  F  +     
Sbjct: 468 GFPLFMRETRSGLYSTGQYYAANILALLPGMIIEPLIFVIICYWLTGLRSTFYAFGVTAM 527

Query: 406 -VFFTLNV---YGCL--SVIESIMMVVASLVPNFLMGIVTGAGIIGIMMMSSGFFRLLSD 459
            V   +NV    GC   +   S+ + +A LVP           +  I M++SG F  ++ 
Sbjct: 528 CVVLVMNVATACGCFFSTAFNSVPLAMAYLVP-----------LDYIFMITSGIFIQVNS 576

Query: 460 LPKVVW 465
           LP   W
Sbjct: 577 LPVAFW 582


>ABG5_HUMAN (Q9H222) ATP-binding cassette, sub-family G, member 5
           (Sterolin-1)
          Length = 651

 Score =  174 bits (441), Expect = 5e-43
 Identities = 131/504 (25%), Positives = 240/504 (46%), Gaps = 63/504 (12%)

Query: 3   GNVLLNGK--KKIPDYGFVAYVTQEDVLLGTLTVKETIAYSAHLRL----PSTMSKEEVS 56
           G V +NG+  ++       +YV Q D LL +LTV+ET+ Y+A L +    P +  K+   
Sbjct: 111 GEVYVNGRALRREQFQDCFSYVLQSDTLLSSLTVRETLHYTALLAIRRGNPGSFQKK--- 167

Query: 57  SIIDGTIIEMGLQDCADRLIGNWHLRGISGGERKRTSIALEILTKPRLLFLDEPTCGLDS 116
             ++  + E+ L   ADRLIGN+ L GIS GER+R SIA ++L  P+++  DEPT GLD 
Sbjct: 168 --VEAVMAELSLSHVADRLIGNYSLGGISTGERRRVSIAAQLLQDPKVMLFDEPTTGLDC 225

Query: 117 ASAFFVVQTLRNIAHDGRTVISSIHQPNSEVFALFDDLFLLARGETVYFGEAKMAIEFFA 176
            +A  +V  L  +A   R V+ +IHQP SE+F LFD + +L+ GE ++ G     ++FF 
Sbjct: 226 MTANQIVVLLVELARRNRIVVLTIHQPRSELFQLFDKIAILSFGELIFCGTPAEMLDFFN 285

Query: 177 EAGFPCPRKRNPSDHFLRCINSDFDVVTATLKGSQRIHDVPNSADPFMNLATAQIKSMLV 236
           + G+PCP   NP D ++       D+ +   +  +R             + T++   M+ 
Sbjct: 286 DCGYPCPEHSNPFDFYM-------DLTSVDTQSKER------------EIETSKRVQMIE 326

Query: 237 ERFKRSTYARRVKYNIQEQ---STNEGIETETNYGSQASWWKQLSTLTRRSFVNMCRD-- 291
             +K+S    +   NI+      T   +  +T        + +L  L RR   N+ R+  
Sbjct: 327 SAYKKSAICHKTLKNIERMKHLKTLPMVPFKTK--DSPGVFSKLGVLLRRVTRNLVRNKL 384

Query: 292 -----------IGYYWLRIIINIIVSICVGTLYFDVGYSYTSILARGACGAFVTGFMTTI 340
                      +G + L  ++ +  ++  G +   VG  Y  + A        TG +  +
Sbjct: 385 AVITRLLQNLIMGLFLLFFVLRVRSNVLKGAIQDRVGLLYQFVGATP-----YTGMLNAV 439

Query: 341 SIGSLPSVIEEMKVFYRERMNGYYGVAAYILANFISSFPFLVVIALTSCTITYNMVKFRP 400
           ++  +   + +     +E  +G Y     +LA  +   PF VV  +   ++ Y  +   P
Sbjct: 440 NLFPVLRAVSD-----QESQDGLYQKWQMMLAYALHVLPFSVVATMIFSSVCYWTLGLHP 494

Query: 401 GFIHYVFFTLNVYGCLSVIESIMMVVASLV--PNFLMGIVTGAGIIGIMMMSSGFFRLLS 458
               + +F+  +     + E + +V+  +V  PN +  +V    I G+ ++ SGF R + 
Sbjct: 495 EVARFGYFSAALLAPHLIGEFLTLVLLGIVQNPNIVNSVVALLSIAGV-LVGSGFLRNIQ 553

Query: 459 DLPKVVWRYPISYISYGAWATQVI 482
           ++P + ++  ISY ++  + ++++
Sbjct: 554 EMP-IPFKI-ISYFTFQKYCSEIL 575


>ABG5_RAT (Q99PE7) ATP-binding cassette, sub-family G, member 5
           (Sterolin-1)
          Length = 652

 Score =  172 bits (437), Expect = 1e-42
 Identities = 131/481 (27%), Positives = 229/481 (47%), Gaps = 53/481 (11%)

Query: 1   MTGNVLLNGKKKIPDY--GFVAYVTQEDVLLGTLTVKETIAYSAHLRLPSTMSKEEVSSI 58
           + G V +NG +   D     V+Y+ Q DV L +LTV+ET+ Y+A L L S+ S +     
Sbjct: 110 LEGEVFVNGCELRRDQFQDCVSYLLQSDVFLSSLTVRETLRYTAMLALRSS-SADFYDKK 168

Query: 59  IDGTIIEMGLQDCADRLIGNWHLRGISGGERKRTSIALEILTKPRLLFLDEPTCGLDSAS 118
           ++  + E+ L   AD++IGN++  GIS GER+R SIA ++L  P+++ LDEPT GLD  +
Sbjct: 169 VEAVLTELSLSHVADQMIGNYNFGGISSGERRRVSIAAQLLQDPKVMMLDEPTTGLDCMT 228

Query: 119 AFFVVQTLRNIAHDGRTVISSIHQPNSEVFALFDDLFLLARGETVYFGEAKMAIEFFAEA 178
           A  +V  L  +A   R VI +IHQP SE+F  FD + +L  GE V+ G  +  + FF   
Sbjct: 229 ANHIVLLLVELARRNRIVIVTIHQPRSELFHHFDKIAILTYGELVFCGTPEEMLGFFNNC 288

Query: 179 GFPCPRKRNPSDHFLRCINSDFDVVTATLKGSQRIHDVPNSADPFMNLATAQIKSMLVER 238
           G+PCP   NP D ++       D+ +   +  +R             + T +   ML   
Sbjct: 289 GYPCPEHSNPFDFYM-------DLTSVDTQSRER------------EIETYKRVQMLESA 329

Query: 239 FKRSTYARRVKYNIQEQ---STNEGIETETNYGSQASWWKQLSTLTRRSFVNMCRDIGYY 295
           F++S    ++  NI+      T   +  +T   +    + +L  L RR   N+ R+    
Sbjct: 330 FRQSDICHKILENIERTRHLKTLPMVPFKTK--NPPGMFCKLGVLLRRVTRNLMRNKQVV 387

Query: 296 WLRIIINIIVSICV-------------GTLYFDVGYSYTSILARGACGAFVTGFMTTISI 342
            +R++ N+I+ + +             G +   VG  Y  + A        TG +  +++
Sbjct: 388 IMRLVQNLIMGLFLIFYLLRVQNNMLKGAVQDRVGLLYQLVGATP-----YTGMLNAVNL 442

Query: 343 GSLPSVIEEMKVFYRERMNGYYGVAAYILANFISSFPFLVVIALTSCTITYNMVKFRPGF 402
             +   + +     +E  +G Y     +LA  + + PF +V  +   ++ Y  +   P  
Sbjct: 443 FPMLRAVSD-----QESQDGLYQKWQMLLAYVLHALPFSIVATVIFSSVCYWTLGLYPEV 497

Query: 403 IHYVFFTLNVYGCLSVIESIMMVVASLV--PNFLMGIVTGAGIIGIMMMSSGFFRLLSDL 460
             + +F+  +     + E + +V+  +V  PN +  IV    I G +++ SGF R + ++
Sbjct: 498 ARFGYFSAALLAPHLIGEFLTLVLLGMVQNPNIVNSIVALLSISG-LLIGSGFIRNIEEM 556

Query: 461 P 461
           P
Sbjct: 557 P 557


>YOH5_YEAST (Q08234) Probable ATP-dependent transporter
           YOL074C/YOL075C
          Length = 1294

 Score =  167 bits (424), Expect = 4e-41
 Identities = 131/472 (27%), Positives = 222/472 (46%), Gaps = 39/472 (8%)

Query: 13  IPDYGFVAYVTQEDVLLGTLTVKETIAYSAHLRLPSTMSKEEVSSIIDGTIIEMGLQDCA 72
           I  +  +AY+ Q+DVL   LT +ET+ ++A L+L S+   +++  +++  I E+GL+DCA
Sbjct: 117 IQKHVIMAYLPQQDVLSPRLTCRETLKFAADLKLNSSERTKKL--MVEQLIEELGLKDCA 174

Query: 73  DRLIGNWHLRGISGGERKRTSIALEILTKPRLLFLDEPTCGLDSASAFFVVQTLRNIA-H 131
           D L+G+   RG+SGGE++R SI  ++++ P ++FLDEPT GLD+ SAF V++TL+ +A  
Sbjct: 175 DTLVGDNSHRGLSGGEKRRLSIGTQMISNPSIMFLDEPTTGLDAYSAFLVIKTLKKLAKE 234

Query: 132 DGRTVISSIHQPNSEVFALFDDLFLLARGETVYFGEAKMAIEFFAEAGFPCPRKRNPSDH 191
           DGRT I SIHQP S++  L D + +L++G  VY  +    I +F   G+  P+  NP+D+
Sbjct: 235 DGRTFIMSIHQPRSDILFLLDQVCILSKGNVVYCDKMDNTIPYFESIGYHVPQLVNPADY 294

Query: 192 FLRCINSDFDVVTATLKGSQRIHDVPNSADPFMNLATAQIKSMLVERFKRSTYARRVKYN 251
           F+                        +S D   +   A  +S L           R    
Sbjct: 295 FIDL----------------------SSVDSRSDKEEAATQSRLNSLIDHWHDYERTHLQ 332

Query: 252 IQEQS--TNEGIETETNYGSQASWWKQLSTLTRRSFVNMCRDIGYYWLRIIINIIVSICV 309
           +Q +S  +N       N  ++  +WKQ++ LTRR+F     D           +I+    
Sbjct: 333 LQAESYISNATEIQIQNMTTRLPFWKQVTVLTRRNFKLNFSDYVTLISTFAEPLIIGTVC 392

Query: 310 GTLYFDVGYSYTSILARGACGAFVTGFMTT---ISIGSLPSVIEEMKVFYRERMNGYYGV 366
           G +Y+    S    L       + +  +     +   +     +++ ++ RER  G    
Sbjct: 393 GWIYYKPDKSSIGGLRTTTACLYASTILQCYLYLLFDTYRLCEQDIALYDRERAEGSVTP 452

Query: 367 AAYILANFISSF---PFLVVIALTSCTITYNMVKFRPGFIHYVFFTLNVYGCLSVIESIM 423
            A+I+A  IS F    F + +   S  ITY M         + +    V+ C      + 
Sbjct: 453 LAFIVARKISLFLSDDFAMTMIFVS--ITYFMFGLEADARKFFYQFAVVFLCQLSCSGLS 510

Query: 424 MVVASLVPNFLMGIVTGAGIIGIMMMSSGFFRLLSDLPKVV-WRYPISYISY 474
           M+  ++  +F    + G     ++ M  GFF     +P  V W   I YI++
Sbjct: 511 MLSVAVSRDFSKASLVGNMTFTVLSMGCGFFVNAKVMPVYVRW---IKYIAF 559



 Score =  147 bits (372), Expect = 5e-35
 Identities = 128/477 (26%), Positives = 205/477 (42%), Gaps = 56/477 (11%)

Query: 20   AYVTQEDV-LLGTLTVKETIAYSAHLRLPSTMSKEEVSSIIDGTIIEMGLQDCADRLIGN 78
            +YV+Q+D  LL  LTVKET+ Y+A LRL      E +    D  I  +GL+ C + +IGN
Sbjct: 775  SYVSQDDDHLLAALTVKETLKYAAALRLHHLTEAERMERT-DNLIRSLGLKHCENNIIGN 833

Query: 79   WHLRGISGGERKRTSIALEILTKPRLLFLDEPTCGLDSASAFFVVQTLRNIAHD-GRTVI 137
              ++GISGGE++R ++ +++L  P +L LDEPT GLDS ++  +++ L  +  + G+T+I
Sbjct: 834  EFVKGISGGEKRRVTMGVQLLNDPPILLLDEPTSGLDSFTSATILEILEKLCREQGKTII 893

Query: 138  SSIHQPNSEVFALFDDLFLLAR-GETVYFGEAKMAIEFFAEAGFPCPRKRNPSDHFLRCI 196
             +IHQP SE+F  F ++ LLA+ G T + G     I +F E G+ CP   N +D FL   
Sbjct: 894  ITIHQPRSELFKRFGNVLLLAKSGRTAFNGSPDEMIAYFTELGYNCPSFTNVADFFL--- 950

Query: 197  NSDFDVVTATLKGSQRIHDVPNSADPFMNLATAQIKSMLVERFKRSTYARRVKYNIQEQS 256
                D+++   +  Q                     + +  R +        K N+  +S
Sbjct: 951  ----DLISVNTQNEQ---------------------NEISSRARVEKILSAWKANMDNES 985

Query: 257  TNEGIETETNYGSQASWWKQLSTLTR--------------RSFVNMCRDIGYYWLRIIIN 302
             +    +E    SQ S++ + S   R              R F    R       RI   
Sbjct: 986  LSPTPISEKQQYSQESFFTEYSEFVRKPANLVLAYIVNVKRQFTTTRRSFDSLMARIAQI 1045

Query: 303  IIVSICVGTLYFDVGYSYTSILARGACGAFVTGFMTTISIGSLPSVIEEMKVFYRERMNG 362
              + +     +  V ++YTSI  R       T       +G+L     E   FY E  + 
Sbjct: 1046 PGLGVIFALFFAPVKHNYTSISNRLGLAQESTALYFVGMLGNLACYPTERDYFYEEYNDN 1105

Query: 363  YYGVAAYILANFISSFPFLVVIALTSCTITY---NMVKFRPGFIHYVFFTLNVYGCLSVI 419
             YG+A + LA      P   + ++     T     + +    F   V+ +  +  C    
Sbjct: 1106 VYGIAPFFLAYMTLELPLSALASVLYAVFTVLACGLPRTAGNFFATVYCSF-IVTCCGER 1164

Query: 420  ESIMMVVASLVPNFLMGIVTGAGIIGIMM---MSSGFFRLLSDLPKVVWRYPISYIS 473
              IM       P F++  ++    IG  M   MS G  R+L       +  P+ Y S
Sbjct: 1165 LGIMTNTFFERPGFVVNCISIILSIGTQMSGLMSLGMSRVLKGFN---YLNPVGYTS 1218


>ABG5_MOUSE (Q99PE8) ATP-binding cassette, sub-family G, member 5
           (Sterolin-1)
          Length = 652

 Score =  166 bits (419), Expect = 2e-40
 Identities = 129/479 (26%), Positives = 224/479 (45%), Gaps = 49/479 (10%)

Query: 1   MTGNVLLNGKKKIPDY--GFVAYVTQEDVLLGTLTVKETIAYSAHLRLPSTMSKEEVSSI 58
           + G V +NG +   D      +YV Q DV L +LTV+ET+ Y+A L L  + S +  +  
Sbjct: 110 LEGEVFVNGCELRRDQFQDCFSYVLQSDVFLSSLTVRETLRYTAMLALCRS-SADFYNKK 168

Query: 59  IDGTIIEMGLQDCADRLIGNWHLRGISGGERKRTSIALEILTKPRLLFLDEPTCGLDSAS 118
           ++  + E+ L   AD++IG+++  GIS GER+R SIA ++L  P+++ LDEPT GLD  +
Sbjct: 169 VEAVMTELSLSHVADQMIGSYNFGGISSGERRRVSIAAQLLQDPKVMMLDEPTTGLDCMT 228

Query: 119 AFFVVQTLRNIAHDGRTVISSIHQPNSEVFALFDDLFLLARGETVYFGEAKMAIEFFAEA 178
           A  +V  L  +A   R VI +IHQP SE+F  FD + +L  GE V+ G  +  + FF   
Sbjct: 229 ANQIVLLLAELARRDRIVIVTIHQPRSELFQHFDKIAILTYGELVFCGTPEEMLGFFNNC 288

Query: 179 GFPCPRKRNPSDHFLRCINSDFDVVTATLKGSQRIHDVPNSADPFMNLATAQIKSMLVER 238
           G+PCP   NP D ++       D+ +   +  +R             + T +   ML   
Sbjct: 289 GYPCPEHSNPFDFYM-------DLTSVDTQSRER------------EIETYKRVQMLECA 329

Query: 239 FKRSTYARRVKYNIQEQSTNEGIET-ETNYGSQASWWKQLSTLTRRSFVNMCRDIGYYWL 297
           FK S    ++  NI+     + + T           + +L  L RR   N+ R+     +
Sbjct: 330 FKESDIYHKILENIERARYLKTLPTVPFKTKDPPGMFGKLGVLLRRVTRNLMRNKQAVIM 389

Query: 298 RIIINIIVSICV-------------GTLYFDVGYSYTSILARGACGAFVTGFMTTISIGS 344
           R++ N+I+ + +             G +   VG  Y  + A        TG +  +++  
Sbjct: 390 RLVQNLIMGLFLIFYLLRVQNNTLKGAVQDRVGLLYQLVGATP-----YTGMLNAVNLFP 444

Query: 345 LPSVIEEMKVFYRERMNGYYGVAAYILANFISSFPFLVVIALTSCTITYNMVKFRPGFIH 404
           +   + +     +E  +G Y     +LA  +   PF V+  +   ++ Y  +   P    
Sbjct: 445 MLRAVSD-----QESQDGLYHKWQMLLAYVLHVLPFSVIATVIFSSVCYWTLGLYPEVAR 499

Query: 405 YVFFTLNVYGCLSVIESIMMVVASLV--PNFLMGIVTGAGIIGIMMMSSGFFRLLSDLP 461
           + +F+  +     + E + +V+  +V  PN +  IV    I G +++ SGF R + ++P
Sbjct: 500 FGYFSAALLAPHLIGEFLTLVLLGIVQNPNIVNSIVALLSISG-LLIGSGFIRNIQEMP 557


>ABG3_MOUSE (Q99P81) ATP-binding cassette, sub-family G, member 3
          Length = 650

 Score =  157 bits (398), Expect = 4e-38
 Identities = 136/496 (27%), Positives = 235/496 (46%), Gaps = 49/496 (9%)

Query: 1   MTGNVLLNGKKKIPDYGFVA-YVTQEDVLLGTLTVKETIAYSAHLRLPSTMSKEEVSSII 59
           ++G++L+NGK +  ++   + YV Q DV+LGT+TV++ + +SA LRLP T++++E    I
Sbjct: 102 LSGDILINGKPRPANFKCTSGYVPQNDVVLGTVTVRDNLEFSAALRLPVTITRDEKRRRI 161

Query: 60  DGTIIEMGLQDCADRLIGNWHLRGISGGERKRTSIALEILTKPRLLFLDEPTCGLDSASA 119
           +  +  + L           +++  S   RKRTSIA+E++T+  +LFLD+PT GLD  + 
Sbjct: 162 NEVLELLHLNK-------EQNIKPRSKELRKRTSIAMELVTEHPILFLDDPTTGLDLRTT 214

Query: 120 FFVVQTLRNIAHDGRTVISSIHQPNSEVFALFDDLFLLARGETVYFGEAKMAIEFFAEAG 179
             V+  LR ++  GRT+I SI+QP   +F  FD L L+A G+ ++ G A+ A+E+F  AG
Sbjct: 215 TDVILVLRRMSKKGRTIIFSINQPQYSIFKFFDSLTLVASGKVMFHGPAQDALEYFRSAG 274

Query: 180 FPCPRKRNPSDHFLRCINSDFDVVTATLKGSQRIHDVPNSADPF--MNLATAQIKSMLVE 237
           +      NP+D FL  IN  F  +  T +     H+     + F      T ++ +M  +
Sbjct: 275 YNYESHNNPADFFLDVINGGFSNILDTEEDG---HEDDKYEELFERQYQVTGKLANMYAQ 331

Query: 238 RFKRSTYARRVKYNIQEQSTNEGIETETNYGSQASWWKQLSTLTRRSFVNMCRDIGYYWL 297
               S     +   + EQ        ET       +  QL  +  +SF N     G+ W+
Sbjct: 332 SPLYSETRAILDQLLGEQKLERSSAVETT--CVTPFCHQLKWIICQSFKNF---KGFPWV 386

Query: 298 RI---IINIIVSICVGTLYFDVGYSYTSILARGACGAFVTGF--MTTISIGSLPSVIEEM 352
            +   II +I++  VGT +  +      +  R      +T F  +T++S G L  VI+ +
Sbjct: 387 TVIQAIITVILATAVGTAFRVLKNDCIEVQMRAGLLYLLTIFQCITSVSAGEL-FVIDRV 445

Query: 353 KVFYRERMNGYYGVAAYILANFISS-FPFLVVIALTSCTITYNMVKFRPGFIHYVFFTLN 411
           + F  E  +GYY V++Y     ++   P  ++ +     ITY +   +            
Sbjct: 446 R-FLHEHTSGYYRVSSYFFGKLLAELIPRRLLPSTVFSLITYVIAGVKMSM--------- 495

Query: 412 VYGCLSVIESIMMVVASLVPNFLMGIVTGAGIIGI--MMMSSGFFRLL----------SD 459
              C   +   +MV+A    +  + I  G   + +  ++++  F  +L          S 
Sbjct: 496 --KCFFTMICTIMVLAYSASSLPLSIGAGENAVAVPTLLVTIYFVFMLFFSGLSLYPGSF 553

Query: 460 LPKVVWRYPISYISYG 475
           LPK+ W    S   YG
Sbjct: 554 LPKLSWIQYFSIPHYG 569


>YQ5C_CAEEL (Q09466) Putative ABC transporter C16C10.12 in
           chromosome III
          Length = 610

 Score =  155 bits (393), Expect = 2e-37
 Identities = 121/482 (25%), Positives = 228/482 (47%), Gaps = 46/482 (9%)

Query: 3   GNVLLNGKKKIPDYGFVA-YVTQEDVLLGTLTVKETIAYSAHLRLPSTMSKEEVSSIIDG 61
           G V +NG K   +   ++ +  Q+++ + TLTV E +   A LR+ +  +K      +D 
Sbjct: 99  GTVKVNGTKIGKEISLISGFAQQQEIFIPTLTVDEYLMIQARLRMKA--NKHTRRERVDE 156

Query: 62  TIIEMGLQDCADRLIGNWHL-RGISGGERKRTSIALEILTKPRLLFLDEPTCGLDSASAF 120
            I  + LQ+C D  IG   L +GISGGE +R + A E+L+ P LLF DEPT GLDS  A 
Sbjct: 157 IIEMLRLQNCRDLKIGTPGLVKGISGGEARRLTFACELLSNPSLLFADEPTSGLDSFMAA 216

Query: 121 FVVQTLRNIAHDGRTVISSIHQPNSEVFALFDDLFLLARGETVYFGEAKMAIEFFAEAGF 180
            VVQ L+N+A+ GRT+   IHQP +E+F  FD +  L+ G+T + G    +++FFA+ G 
Sbjct: 217 SVVQILKNLANSGRTL---IHQPTAELFFQFDKIIFLSMGKTAFMGTPHESVKFFADCGH 273

Query: 181 PCPRKRNPSDHFLRCINSDFDVVTATLKGSQRIHDVPNSADPFMNLATAQIKSMLVERFK 240
           P P+  NP +                     ++  +PN+        + +    ++E ++
Sbjct: 274 PIPKLFNPPEWI-----------------QSKLSVIPNN-----ETKSRETIGKIIEFYE 311

Query: 241 RSTYARRVKYNIQEQSTNEGIETETNYGSQASWWKQLSTLTRRSFVNMCRDIGYYWLRII 300
           +S   ++    I+  +T E       Y     ++ +   L +R+ +++ R      +++I
Sbjct: 312 KSIIHQKSIVEIRVIATTE----LPPYIENPGFFAETGALLKRACLDVIRSPAQMRMKLI 367

Query: 301 INIIVSICVGTLYFDVGYSYTSILARGACGAFVTGFMTTISIGSLPSVIE-EMKVFYRER 359
             +++ + +G+LY+        +    +   F+   +T  ++  + + +E E+ +  RE 
Sbjct: 368 QKVVMGLFIGSLYWQQPLDPRGVRNTNSALYFLIAELTFSTMFGIMTFMEHELPLIAREY 427

Query: 360 MNGYYGVAAYILANFISSFPFLVVIALTSCTITYNMVKFRPGFIHYVFFTLNVYGCLSVI 419
            +G + V +Y ++ F+S  P   +       I+Y M+     +              S++
Sbjct: 428 HDGLFYVISYYISRFLSYLPLFTIDGALMIVISYWMIGLNSTWQQV---------AKSIL 478

Query: 420 ESIMMVVASLVPNFLMGIV--TGAGIIGIMMMSSGFFRLLSDLPKVVWRYPISYISYGAW 477
            S+++  ++      +  +  T +  I   + +SG F LLS L      +P+ YI +  W
Sbjct: 479 ISVLVEQSATSCGLFLACLFETTSLAIAFAVPASGLFALLSGLYGNTNNFPV-YIRWMQW 537

Query: 478 AT 479
            +
Sbjct: 538 TS 539


>CGR1_CANGA (O74208) ATP-binding cassette transporter CGR1
            (Pleomorphic drug resistance homolog)
          Length = 1542

 Score =  154 bits (389), Expect = 5e-37
 Identities = 116/412 (28%), Positives = 207/412 (50%), Gaps = 42/412 (10%)

Query: 1    MTGNVLLNGKKKIPDYG-FVAYVTQEDVLLGTLTVKETIAYSAHLRLPSTMSKEEVSSII 59
            +TG+V++NG+ +   +   + Y  Q+D+ L T TV+E++ +SA+LR PS++S EE +  +
Sbjct: 943  ITGDVMVNGRPRDTSFSRSIGYCQQQDLHLKTATVRESLRFSAYLRQPSSVSIEEKNEYV 1002

Query: 60   DGTIIEMGLQDCADRLIGNWHLRGISGGERKRTSIALEILTKPRLL-FLDEPTCGLDSAS 118
            +  I  + ++  AD ++G     G++  +RKR +I +E+  KP+LL FLDEPT GLDS +
Sbjct: 1003 EAVIKILEMETYADAVVGVPG-EGLNVEQRKRLTIGVELAAKPKLLVFLDEPTSGLDSQT 1061

Query: 119  AFFVVQTLRNIAHDGRTVISSIHQPNSEVFALFDD-LFLLARGETVYFGE----AKMAIE 173
            A+   Q ++ +A+ G+ ++ +IHQP++ +   FD  LFL   G+TVYFG+     K  I+
Sbjct: 1062 AWATCQLMKKLANHGQAILCTIHQPSAMLMQEFDRLLFLQKGGQTVYFGDLGKGCKTMIK 1121

Query: 174  FFAEAG-FPCPRKRNPSDHFLRCINSDFDVVTATLKGSQRIHDVPNSADPFMNLATAQIK 232
            +F + G   CP   NP++  L  + +           +Q  H+V  +++ F      Q+K
Sbjct: 1122 YFEDHGAHKCPPDANPAEWMLEVVGA-----APGSHANQDYHEVWRNSEQF-----KQVK 1171

Query: 233  SMLVERFKRSTYARRVKYNIQEQSTNEGIETETNYGSQASWWKQLSTLTRRSFVNMCRDI 292
              L +  K  +         Q++  N   + + N     S W Q   +  R F    R  
Sbjct: 1172 QELEQMEKELS---------QKELDN---DEDANKEFATSLWYQFQLVCVRLFQQYWRTP 1219

Query: 293  GYYWLRIIINIIVSICVGTLYFDVGYSYTSILARGACGAFVTGFMTTISIGS-----LPS 347
             Y W + I+ I   + +G  +F   ++      +G     ++ FM T+         LP+
Sbjct: 1220 DYLWSKYILTIFNQLFIGFTFFKADHT-----LQGLQNQMLSIFMYTVIFNPLLQQYLPT 1274

Query: 348  VIEEMKVF-YRERMNGYYGVAAYILANFISSFPFLVVIALTSCTITYNMVKF 398
             +++  ++  RER +  +   A+ILA  +   P+ +V    +  I Y  V F
Sbjct: 1275 FVQQRDLYEARERPSRTFSWKAFILAQIVVEVPWNIVAGTLAYCIYYYSVGF 1326



 Score =  120 bits (302), Expect = 6e-27
 Identities = 117/461 (25%), Positives = 202/461 (43%), Gaps = 38/461 (8%)

Query: 17  GFVAYVTQEDVLLGTLTVKETIAYSAHLRLPSTMSK-----EEVSSIIDGTIIEMGLQDC 71
           G V Y  + D+ L  LTV +T+   A L+ P    K     +  + + D  +   GL   
Sbjct: 236 GEVVYNAEADIHLPHLTVYQTLVTVARLKTPQNRVKGVTREDFANHVTDVAMATYGLSHT 295

Query: 72  ADRLIGNWHLRGISGGERKRTSIALEILTKPRLLFLDEPTCGLDSASAFFVVQTLRNIAH 131
            D  +GN  +RG+SGGERKR SIA   +   +    D  T GLDSA+A   V+ L+  AH
Sbjct: 296 RDTKVGNDLVRGVSGGERKRVSIAEVWICGSKFQCWDNATRGLDSATALEFVRALKTQAH 355

Query: 132 DGRTVIS-SIHQPNSEVFALFDDLFLLARGETVYFGEAKMAIEFFAEAGFPCPRKRNPSD 190
             + V + +I+Q + + + LF+ + +L  G  +YFG+A+ A  +F + G+ CP+++   D
Sbjct: 356 IAKNVATVAIYQCSQDAYNLFNKVSVLYEGYQIYFGDAQHAKVYFQKMGYFCPKRQTIPD 415

Query: 191 HFLRCINSDFDVVTATLKGSQRIHDVPNSADPFMNLATAQIKSMLVERFKRSTYARRVKY 250
            FL  I S            +RI    N       +   Q    +VE +  S   ++++ 
Sbjct: 416 -FLTSITS---------PAERRI----NKEYLDKGIKVPQTPLDMVEYWHNSEEYKQLRE 461

Query: 251 NIQE----QSTNEGIE-TETNYGSQA-----------SWWKQLSTLTRRSFVNMCRDIGY 294
            I E    QS ++  E  E +   Q+           S+  Q+  +  R+F  +      
Sbjct: 462 EIDETLAHQSEDDKEEIKEAHIAKQSKRARPSSPYVVSYMMQVKYILIRNFWRIKNSASV 521

Query: 295 YWLRIIINIIVSICVGTLYFDV--GYSYTSILARGACGAFVTGFMTTISIGSLPSVIEEM 352
              ++  N  ++  +G++++ +  G S  +   RGA   F   F    S+  + S+ E  
Sbjct: 522 TLFQVFGNSAMAFILGSMFYKIQKGSSADTFYFRGAAMFFAILFNAFSSLLEIFSLYEAR 581

Query: 353 KVFYRERMNGYYGVAAYILANFISSFPFLVVIALTSCTITYNMVKFRPGFIHYVFFTLNV 412
            +  + R    Y  +A   A+ IS  P  +V A+    I Y +V FR     + F+ L  
Sbjct: 582 PITEKHRTYSLYHPSADAFASVISEIPPKIVTAILFNIIFYFLVNFRRDAGRFFFYFLIN 641

Query: 413 YGCLSVIESIMMVVASLVPNFLMGIVTGAGIIGIMMMSSGF 453
              +  +  +   V SL       +V  + ++  + M +GF
Sbjct: 642 VIAVFAMSHLFRCVGSLTKTLQEAMVPASMLLLALSMYTGF 682


  Database: sprot
    Posted date:  Nov 25, 2004 10:54 AM
  Number of letters in database: 59,974,054
  Number of sequences in database:  164,201
  
Lambda     K      H
   0.325    0.140    0.418 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 54,055,615
Number of Sequences: 164201
Number of extensions: 2175861
Number of successful extensions: 8450
Number of sequences better than 10.0: 915
Number of HSP's better than 10.0 without gapping: 776
Number of HSP's successfully gapped in prelim test: 139
Number of HSP's that attempted gapping in prelim test: 7208
Number of HSP's gapped (non-prelim): 1195
length of query: 485
length of database: 59,974,054
effective HSP length: 114
effective length of query: 371
effective length of database: 41,255,140
effective search space: 15305656940
effective search space used: 15305656940
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 68 (30.8 bits)