BLAST2 result
BLASTP 2.2.2 [Dec-14-2001]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= AC144731.8 - phase: 0
(517 letters)
Database: sprot
164,201 sequences; 59,974,054 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
PDA6_MEDSA (P38661) Probable protein disulfide-isomerase A6 prec... 59 2e-08
PDA3_HUMAN (P30101) Protein disulfide-isomerase A3 precursor (EC... 59 4e-08
PDA6_ARATH (O22263) Probable protein disulfide-isomerase A6 prec... 58 5e-08
PDA3_RAT (P11598) Protein disulfide-isomerase A3 precursor (EC 5... 58 5e-08
PDA3_BOVIN (P38657) Protein disulfide-isomerase A3 precursor (EC... 57 9e-08
PDI_WHEAT (P52589) Protein disulfide-isomerase precursor (EC 5.3... 55 3e-07
PDI_HORVU (P80284) Protein disulfide-isomerase precursor (EC 5.3... 55 3e-07
PDA3_MOUSE (P27773) Protein disulfide-isomerase A3 precursor (EC... 55 6e-07
PDI_DATGL (Q9XF61) Protein disulfide-isomerase precursor (EC 5.3... 53 2e-06
MPD1_YEAST (Q12404) Protein disulfide-isomerase MPD1 precursor (... 52 5e-06
PDI_RICCO (Q43116) Protein disulfide-isomerase precursor (EC 5.3... 51 6e-06
ER60_SCHMA (P38658) Probable protein disulfide-isomerase ER-60 p... 51 6e-06
PDI_MEDSA (P29828) Protein disulfide-isomerase precursor (EC 5.3... 51 8e-06
PDA4_MOUSE (P08003) Protein disulfide-isomerase A4 precursor (EC... 51 8e-06
PDI1_CAEEL (Q17967) Protein disulfide-isomerase 1 precursor (EC ... 50 1e-05
PDI2_SCHPO (O13811) Putative protein disulfide-isomerase C17H9.1... 50 1e-05
PDI_MAIZE (P52588) Protein disulfide-isomerase precursor (EC 5.3... 50 2e-05
PDA4_RAT (P38659) Protein disulfide-isomerase A4 precursor (EC 5... 50 2e-05
PDA4_HUMAN (P13667) Protein disulfide-isomerase A4 precursor (EC... 50 2e-05
PDA4_CAEEL (P34329) Probable protein disulfide-isomerase A4 prec... 48 5e-05
>PDA6_MEDSA (P38661) Probable protein disulfide-isomerase A6
precursor (EC 5.3.4.1) (P5)
Length = 364
Score = 59.3 bits (142), Expect = 2e-08
Identities = 40/128 (31%), Positives = 59/128 (45%), Gaps = 21/128 (16%)
Query: 48 DYAVELNATNFDAVLKDTPATFAVVEFFANWCPACRNYKPHYEKVAKLFNGPDAVHPGII 107
D V L NF+ + A+VEF+A WC C+ P YEK+ F +V
Sbjct: 29 DDVVVLTEENFEKEVGHDKG--ALVEFYAPWCGHCKKLAPEYEKLPNSFKKAKSV----- 81
Query: 108 LLTRVDCASKINIKLCDKFSVGHYPMLFWGPPPKFVGGSWEPKQEKSDIHVIDDARTADR 167
L+ +VDC ++ C K+ V YP + W P GS EPK+ + RTA+
Sbjct: 82 LIAKVDCDEHKSV--CSKYGVSGYPTIQWFPK-----GSLEPKK-------FEGPRTAES 127
Query: 168 LLNWINKQ 175
L ++N +
Sbjct: 128 LAEFVNTE 135
Score = 46.6 bits (109), Expect = 2e-04
Identities = 48/189 (25%), Positives = 78/189 (40%), Gaps = 23/189 (12%)
Query: 45 TDHDYAVELNATNFDAVLKDTPATFAVVEFFANWCPACRNYKPHYEKVAKLFNGPDAVHP 104
T + V L F+ V+ D +VEF+A WC C++ P YEKVA +F D V
Sbjct: 144 TAPSHVVVLTPETFNEVVLDGTKD-VLVEFYAPWCGHCKSLAPIYEKVAAVFKSEDDV-- 200
Query: 105 GIILLTRVDCASKINIKLCDKFSVGHYPMLFWGPPPKFVGGSWEPKQEKSDIHVIDDART 164
++ +D A K L +K+ V +P L + P G + R
Sbjct: 201 ---VIANLD-ADKYR-DLAEKYDVSGFPTLKFFPKGNKAGEDY------------GGGRD 243
Query: 165 ADRLLNWINKQMSSSFGLDDQKFQNEHLSSNVSDPEQIARAIYDVEEATSLAFDIILENK 224
D + +IN++ +S D K Q + V D +++ + + A +E +
Sbjct: 244 LDDFVAFINEKSGTS---RDAKGQLTSEAGIVEDLDELVKEFVAANDEEKKAVFARIEEE 300
Query: 225 MIKPETRAS 233
+ K E AS
Sbjct: 301 VKKLEGSAS 309
>PDA3_HUMAN (P30101) Protein disulfide-isomerase A3 precursor (EC
5.3.4.1) (Disulfide isomerase ER-60) (ERp60) (58 kDa
microsomal protein) (p58) (ERp57) (58 kDa glucose
regulated protein)
Length = 505
Score = 58.5 bits (140), Expect = 4e-08
Identities = 39/126 (30%), Positives = 58/126 (45%), Gaps = 23/126 (18%)
Query: 51 VELNATNFDAVLKDT-PATFAVVEFFANWCPACRNYKPHYEKVAKLFNGPDAVHPGIILL 109
+EL NF++ + DT A +VEFFA WC C+ P YE A GI+ L
Sbjct: 28 LELTDDNFESRISDTGSAGLMLVEFFAPWCGHCKRLAPEYEAAATRLK-------GIVPL 80
Query: 110 TRVDCASKINIKLCDKFSVGHYPMLFWGPPPKFVGGSWEPKQEKSDIHVIDDARTADRLL 169
+VDC + N C+K+ V YP L + ++ + D RTAD ++
Sbjct: 81 AKVDCTA--NTNTCNKYGVSGYPTL-------------KIFRDGEEAGAYDGPRTADGIV 125
Query: 170 NWINKQ 175
+ + KQ
Sbjct: 126 SHLKKQ 131
Score = 40.4 bits (93), Expect = 0.011
Identities = 25/98 (25%), Positives = 49/98 (49%), Gaps = 17/98 (17%)
Query: 55 ATNFDAVLKDTPATFAVVEFFANWCPACRNYKPHYEKVA-KLFNGPDAVHPGIILLTRVD 113
A NFD ++ + ++EF+A WC C+N +P Y+++ KL P+ I++ ++D
Sbjct: 383 AENFDEIVNNENKD-VLIEFYAPWCGHCKNLEPKYKELGEKLSKDPN------IVIAKMD 435
Query: 114 CASKINIKLCDKFSVGHYPMLFWGP------PPKFVGG 145
+ + + V +P +++ P P K+ GG
Sbjct: 436 ATAN---DVPSPYEVRGFPTIYFSPANKKLNPKKYEGG 470
>PDA6_ARATH (O22263) Probable protein disulfide-isomerase A6
precursor (EC 5.3.4.1) (P5)
Length = 361
Score = 58.2 bits (139), Expect = 5e-08
Identities = 34/106 (32%), Positives = 53/106 (49%), Gaps = 19/106 (17%)
Query: 70 AVVEFFANWCPACRNYKPHYEKVAKLFNGPDAVHPGIILLTRVDCASKINIKLCDKFSVG 129
A+VEF+A WC C+ P YEK+ F +V L+ +VDC + ++ C K+ V
Sbjct: 43 ALVEFYAPWCGHCKKLAPEYEKLGASFKKAKSV-----LIAKVDCDEQKSV--CTKYGVS 95
Query: 130 HYPMLFWGPPPKFVGGSWEPKQEKSDIHVIDDARTADRLLNWINKQ 175
YP + W P GS EP++ + R A+ L ++NK+
Sbjct: 96 GYPTIQWFPK-----GSLEPQK-------YEGPRNAEALAEYVNKE 129
Score = 50.1 bits (118), Expect = 1e-05
Identities = 39/129 (30%), Positives = 62/129 (47%), Gaps = 20/129 (15%)
Query: 51 VELNATNFDAVLKDTPATFAVVEFFANWCPACRNYKPHYEKVAKLFNGPDAVHPGIILLT 110
V L NFD ++ D +VEF+A WC C++ P YEKVA +F + V ++
Sbjct: 144 VVLTPDNFDEIVLDQNKD-VLVEFYAPWCGHCKSLAPTYEKVATVFKQEEGV-----VIA 197
Query: 111 RVDCASKINIKLCDKFSVGHYPMLFWGPPPKFVGGSWEPKQEKSDIHVIDDARTADRLLN 170
+D + + L +K+ V +P L KF PK K+ H D R D ++
Sbjct: 198 NLD--ADAHKALGEKYGVSGFPTL------KFF-----PKDNKAG-HDYDGGRDLDDFVS 243
Query: 171 WINKQMSSS 179
+IN++ +S
Sbjct: 244 FINEKSGTS 252
>PDA3_RAT (P11598) Protein disulfide-isomerase A3 precursor (EC
5.3.4.1) (Disulfide isomerase ER-60) (ERp60) (58 kDa
microsomal protein) (p58) (ERp57) (HIP-70) (Q-2)
Length = 505
Score = 58.2 bits (139), Expect = 5e-08
Identities = 39/126 (30%), Positives = 58/126 (45%), Gaps = 23/126 (18%)
Query: 51 VELNATNFDAVLKDT-PATFAVVEFFANWCPACRNYKPHYEKVAKLFNGPDAVHPGIILL 109
+EL NF++ + DT A +VEFFA WC C+ P YE A GI+ L
Sbjct: 28 LELTDENFESRVSDTGSAGLMLVEFFAPWCGHCKRLAPEYEAAATRLK-------GIVPL 80
Query: 110 TRVDCASKINIKLCDKFSVGHYPMLFWGPPPKFVGGSWEPKQEKSDIHVIDDARTADRLL 169
+VDC + N C+K+ V YP L + ++ + D RTAD ++
Sbjct: 81 AKVDCTA--NTNTCNKYGVSGYPTL-------------KIFRDGEEAGAYDGPRTADGIV 125
Query: 170 NWINKQ 175
+ + KQ
Sbjct: 126 SHLKKQ 131
Score = 37.4 bits (85), Expect = 0.094
Identities = 21/82 (25%), Positives = 42/82 (50%), Gaps = 16/82 (19%)
Query: 71 VVEFFANWCPACRNYKPHYEKVA-KLFNGPDAVHPGIILLTRVDCASKINIKLCDKFSVG 129
++EF+A WC C+N +P Y+++ KL P+ I++ ++D + + + V
Sbjct: 398 LIEFYAPWCGHCKNLEPKYKELGEKLSKDPN------IVIAKMDATAN---DVPSPYEVK 448
Query: 130 HYPMLFWGP------PPKFVGG 145
+P +++ P P K+ GG
Sbjct: 449 GFPTIYFSPANKKLTPKKYEGG 470
>PDA3_BOVIN (P38657) Protein disulfide-isomerase A3 precursor (EC
5.3.4.1) (Disulfide isomerase ER-60) (ERP60) (58 kDa
microsomal protein) (P58) (ERp57)
Length = 505
Score = 57.4 bits (137), Expect = 9e-08
Identities = 38/126 (30%), Positives = 59/126 (46%), Gaps = 23/126 (18%)
Query: 51 VELNATNFDAVLKDTPAT-FAVVEFFANWCPACRNYKPHYEKVAKLFNGPDAVHPGIILL 109
+EL NF++ + DT ++ +VEFFA WC C+ P YE A GI+ L
Sbjct: 28 LELTDDNFESRITDTGSSGLMLVEFFAPWCGHCKKLAPEYEAAATRLK-------GIVPL 80
Query: 110 TRVDCASKINIKLCDKFSVGHYPMLFWGPPPKFVGGSWEPKQEKSDIHVIDDARTADRLL 169
+VDC + N C+K+ V YP L + ++ + D RTAD ++
Sbjct: 81 AKVDCTA--NTNTCNKYGVSGYPTL-------------KIFRDGEESGAYDGPRTADGIV 125
Query: 170 NWINKQ 175
+ + KQ
Sbjct: 126 SHLKKQ 131
Score = 40.0 bits (92), Expect = 0.015
Identities = 25/98 (25%), Positives = 49/98 (49%), Gaps = 17/98 (17%)
Query: 55 ATNFDAVLKDTPATFAVVEFFANWCPACRNYKPHYEKVA-KLFNGPDAVHPGIILLTRVD 113
A NFD ++ + ++EF+A WC C+N +P Y+++ KL P+ I++ ++D
Sbjct: 383 AENFDEIVNNENKD-VLIEFYAPWCGHCKNLEPKYKELGEKLRKDPN------IVIAKMD 435
Query: 114 CASKINIKLCDKFSVGHYPMLFWGP------PPKFVGG 145
+ + + V +P +++ P P K+ GG
Sbjct: 436 ATAN---DVPSPYEVRGFPTIYFSPANKKQNPKKYEGG 470
>PDI_WHEAT (P52589) Protein disulfide-isomerase precursor (EC
5.3.4.1) (PDI)
Length = 515
Score = 55.5 bits (132), Expect = 3e-07
Identities = 31/82 (37%), Positives = 44/82 (52%), Gaps = 6/82 (7%)
Query: 53 LNATNFDAVLKDTPATFAVVEFFANWCPACRNYKPHYEKVAKLFNGPDAVHPGIILLTRV 112
L+A NFD + P F +VEF+A WC C++ P YEK A+L + H I+L +V
Sbjct: 44 LHADNFDDAIAKHP--FILVEFYAPWCGHCKSLAPEYEKAAQLL----SKHDPAIVLAKV 97
Query: 113 DCASKINIKLCDKFSVGHYPML 134
D + N L K+ V +P L
Sbjct: 98 DANDEKNKPLAGKYEVQGFPTL 119
Score = 33.5 bits (75), Expect = 1.4
Identities = 28/125 (22%), Positives = 51/125 (40%), Gaps = 31/125 (24%)
Query: 59 DAVLKDTPATFAVVEFFANWCPACRNYKPHYEKVAKLFNGPDAVHPGIILLTRVDCASKI 118
D V K A ++EF+A WC C+ P ++ A + V ++ ++D +
Sbjct: 394 DVVFKS--AKNVLIEFYAPWCGHCKKLAPILDEAAATLQSEEDV-----VIAKIDATAN- 445
Query: 119 NIKLCDKFSVGHYPMLFW----GPPPKFVGGSWEPKQEKSDIHVIDDARTADRLLNWINK 174
+ +F V YP L++ G + GG RTAD ++++I K
Sbjct: 446 --DVPGEFDVQGYPTLYFVTPSGKKVSYEGG-----------------RTADEIVDYIKK 486
Query: 175 QMSSS 179
++
Sbjct: 487 NKETA 491
>PDI_HORVU (P80284) Protein disulfide-isomerase precursor (EC
5.3.4.1) (PDI) (Endosperm protein E-1)
Length = 513
Score = 55.5 bits (132), Expect = 3e-07
Identities = 31/82 (37%), Positives = 44/82 (52%), Gaps = 6/82 (7%)
Query: 53 LNATNFDAVLKDTPATFAVVEFFANWCPACRNYKPHYEKVAKLFNGPDAVHPGIILLTRV 112
L+A NFD + P F +VEF+A WC C++ P YEK A+L + H I+L +V
Sbjct: 43 LHADNFDDAIGQHP--FILVEFYAPWCGHCKSLAPEYEKAAQLL----SKHDPAIVLAKV 96
Query: 113 DCASKINIKLCDKFSVGHYPML 134
D + N L K+ V +P L
Sbjct: 97 DANDEKNKPLAGKYEVQGFPTL 118
Score = 31.6 bits (70), Expect = 5.2
Identities = 24/113 (21%), Positives = 46/113 (40%), Gaps = 29/113 (25%)
Query: 71 VVEFFANWCPACRNYKPHYEKVAKLFNGPDAVHPGIILLTRVDCASKINIKLCDKFSVGH 130
++EF+A WC C+ P ++ A + V ++ ++D + +F V
Sbjct: 403 LIEFYAPWCGHCKKLAPILDEAAATLQSEEDV-----VIAKMDATEN---DVPGEFDVQG 454
Query: 131 YPMLFW----GPPPKFVGGSWEPKQEKSDIHVIDDARTADRLLNWINKQMSSS 179
YP L++ G + GG RTAD ++++I K ++
Sbjct: 455 YPTLYFVTPSGKKVSYEGG-----------------RTADEIVDYIRKNKETA 490
>PDA3_MOUSE (P27773) Protein disulfide-isomerase A3 precursor (EC
5.3.4.1) (Disulfide isomerase ER-60) (ERp60) (58 kDa
microsomal protein) (p58) (ERp57)
Length = 504
Score = 54.7 bits (130), Expect = 6e-07
Identities = 40/126 (31%), Positives = 56/126 (43%), Gaps = 24/126 (19%)
Query: 51 VELNATNFDAVLKDT-PATFAVVEFFANWCPACRNYKPHYEKVAKLFNGPDAVHPGIILL 109
+EL NF++ + DT A +VEFFA WC C+ P YE A I+ L
Sbjct: 28 LELTDENFESRVSDTGSAGLMLVEFFAPWCGHCKRLAPEYEAAATRLK--------IVPL 79
Query: 110 TRVDCASKINIKLCDKFSVGHYPMLFWGPPPKFVGGSWEPKQEKSDIHVIDDARTADRLL 169
+VDC + N C+K+ V YP L F G + D RTAD ++
Sbjct: 80 AKVDCTA--NTNTCNKYGVSGYPTL-----KIFRAG--------EEAGAYDGPRTADGIV 124
Query: 170 NWINKQ 175
+ + KQ
Sbjct: 125 SHLKKQ 130
Score = 40.8 bits (94), Expect = 0.009
Identities = 25/98 (25%), Positives = 49/98 (49%), Gaps = 17/98 (17%)
Query: 55 ATNFDAVLKDTPATFAVVEFFANWCPACRNYKPHYEKVA-KLFNGPDAVHPGIILLTRVD 113
A NFD ++ + ++EF+A WC C+N +P Y+++ KL P+ I++ ++D
Sbjct: 382 AENFDDIVNEEDKD-VLIEFYAPWCGHCKNLEPKYKELGEKLSKDPN------IVIAKMD 434
Query: 114 CASKINIKLCDKFSVGHYPMLFWGP------PPKFVGG 145
+ + + V +P +++ P P K+ GG
Sbjct: 435 ATAN---DVPSPYEVKGFPTIYFSPANKKLTPKKYEGG 469
>PDI_DATGL (Q9XF61) Protein disulfide-isomerase precursor (EC
5.3.4.1) (PDI)
Length = 507
Score = 52.8 bits (125), Expect = 2e-06
Identities = 29/88 (32%), Positives = 46/88 (51%), Gaps = 8/88 (9%)
Query: 48 DYAVELNATNF-DAVLKDTPATFAVVEFFANWCPACRNYKPHYEKVAKLFNGPDAVHPGI 106
++ + L+ +NF D V K F VVEF+A WC C+ P YEK A + + H
Sbjct: 33 EFVLTLDKSNFFDTVSKHN---FIVVEFYAPWCGHCKKLAPEYEKAASILSS----HDPP 85
Query: 107 ILLTRVDCASKINIKLCDKFSVGHYPML 134
++L +VD + N +L +F V +P +
Sbjct: 86 VILAKVDANEEANKELASEFEVRGFPTI 113
Score = 37.4 bits (85), Expect = 0.094
Identities = 28/110 (25%), Positives = 47/110 (42%), Gaps = 22/110 (20%)
Query: 71 VVEFFANWCPACRNYKPHYEKVAKLF-NGPDAVHPGIILLTRVDCASKINIKLCDKFSVG 129
++EF+A WC C+ P ++VA F N PD +L+ ++D + N + F V
Sbjct: 399 LLEFYAPWCGHCKQLAPILDEVAVSFENDPD------VLIAKLDATA--NDYPTNTFDVK 450
Query: 130 HYPMLFWGPPPKFVGGSWEPKQEKSDIHVIDDARTADRLLNWINKQMSSS 179
YP L++ K ++ D RT + + +I K S
Sbjct: 451 GYPTLYF-------------KSASGELLQYDGGRTKEDFIEFIEKNREKS 487
>MPD1_YEAST (Q12404) Protein disulfide-isomerase MPD1 precursor (EC
5.3.4.1)
Length = 318
Score = 51.6 bits (122), Expect = 5e-06
Identities = 29/90 (32%), Positives = 44/90 (48%), Gaps = 8/90 (8%)
Query: 52 ELNATNFDAVLKDTPATFAVVEFFANWCPACRNYKPHYEKVAKLFNGPDAVHPGIILLTR 111
EL +FD + +T T ++VEF+A WC C+ + K AK +G ++ +
Sbjct: 33 ELTPKSFDKAIHNTNYT-SLVEFYAPWCGHCKKLSSTFRKAAKRLDG-------VVQVAA 84
Query: 112 VDCASKINIKLCDKFSVGHYPMLFWGPPPK 141
V+C N LC K+ V +P L PPK
Sbjct: 85 VNCDLNKNKALCAKYDVNGFPTLMVFRPPK 114
>PDI_RICCO (Q43116) Protein disulfide-isomerase precursor (EC
5.3.4.1) (PDI)
Length = 498
Score = 51.2 bits (121), Expect = 6e-06
Identities = 28/83 (33%), Positives = 44/83 (52%), Gaps = 8/83 (9%)
Query: 53 LNATNF-DAVLKDTPATFAVVEFFANWCPACRNYKPHYEKVAKLFNGPDAVHPGIILLTR 111
L++TNF D + K F VVEF+A WC C+ +P YEK A + D ++L +
Sbjct: 37 LDSTNFTDTISKHD---FIVVEFYAPWCGHCKKLRPEYEKAASILKSHDIP----VVLAK 89
Query: 112 VDCASKINIKLCDKFSVGHYPML 134
VD + N +L ++ + +P L
Sbjct: 90 VDANEEANKELATQYDIKGFPTL 112
Score = 33.1 bits (74), Expect = 1.8
Identities = 27/120 (22%), Positives = 50/120 (41%), Gaps = 26/120 (21%)
Query: 71 VVEFFANWCPACRNYKPHYEKVAKLFNGPDAVHPGIILLTRVDCASKINIKLCDKFSVGH 130
++EF+A WC C+ P ++VA + I++ ++D + N D F V
Sbjct: 398 LLEFYAPWCGHCKQLAPILDEVAVSYKS-----DADIVIAKLDATA--NDIPSDTFDVRG 450
Query: 131 YPMLFWGPPPKFVGGSWEPKQEKSDIHVIDDARTADRLLNWINK------QMSSSFGLDD 184
YP +++ + + D RT D ++++I K Q S+ G D+
Sbjct: 451 YPTVYF-------------RSASGKVEQYDGDRTKDDIISFIEKNRDKAAQQESANGKDE 497
>ER60_SCHMA (P38658) Probable protein disulfide-isomerase ER-60
precursor (EC 5.3.4.1) (ERP60)
Length = 484
Score = 51.2 bits (121), Expect = 6e-06
Identities = 28/84 (33%), Positives = 44/84 (52%), Gaps = 8/84 (9%)
Query: 51 VELNATNFDAVLKDTPATFAVVEFFANWCPACRNYKPHYEKVAKLFNGPDAVHPGIILLT 110
+EL NF + LK P A+V+F+A WC C+ P + A++ +G + L
Sbjct: 20 LELTKDNFHSELKSIPV--ALVKFYAPWCGHCKKLAPEFTSAAQIISG----KTNDVKLV 73
Query: 111 RVDCASKINIKLCDKFSVGHYPML 134
+VDC ++ +I C +F V YP L
Sbjct: 74 KVDCTTQESI--CSEFGVSGYPTL 95
Score = 40.0 bits (92), Expect = 0.015
Identities = 32/115 (27%), Positives = 54/115 (46%), Gaps = 12/115 (10%)
Query: 44 TTDHDYAVELNATNFDAVLKDTPATFAVVEFFANWCPACRNYKPHYEKVA-KLFNGPDAV 102
T D +L A NFD ++ + VV F A WC C+N P YE+ A K+ N P+
Sbjct: 354 TDDSSAVKKLVALNFDEIVNNEEKDVMVV-FHAGWCGHCKNLMPKYEEAASKVKNEPN-- 410
Query: 103 HPGIILLTRVDCASKINIKLCDKFSVGHYPMLFWGPPPKFVGG-SWEPKQEKSDI 156
++L +D + + + V +P +++ P K S+E ++ +DI
Sbjct: 411 ----LVLAAMDATAN---DVPSPYQVRGFPTIYFVPKGKKSSPVSYEGGRDTNDI 458
>PDI_MEDSA (P29828) Protein disulfide-isomerase precursor (EC
5.3.4.1) (PDI)
Length = 512
Score = 50.8 bits (120), Expect = 8e-06
Identities = 28/95 (29%), Positives = 47/95 (49%), Gaps = 6/95 (6%)
Query: 40 DQTGTTDHDYAVELNATNFDAVLKDTPATFAVVEFFANWCPACRNYKPHYEKVAKLFNGP 99
+++ T ++ + L+ TNF +K F VVEF+A WC C+ P YEK A +
Sbjct: 25 EESSTDAKEFVLTLDNTNFHDTVKKHD--FIVVEFYAPWCGHCKKLAPEYEKAASIL--- 79
Query: 100 DAVHPGIILLTRVDCASKINIKLCDKFSVGHYPML 134
+ H ++L +VD + N L + V +P +
Sbjct: 80 -STHEPPVVLAKVDANEEHNKDLASENDVKGFPTI 113
Score = 33.9 bits (76), Expect = 1.0
Identities = 29/131 (22%), Positives = 51/131 (38%), Gaps = 22/131 (16%)
Query: 44 TTDHDYAVELNATNFDAVLKDTPATFAVVEFFANWCPACRNYKPHYEKVAKLFNGPDAVH 103
T + V + T D V K ++EF+A WC C+ P ++VA F
Sbjct: 374 TNNEPVKVVVGQTLEDVVFKS--GKNVLIEFYAPWCGHCKQLAPILDEVAVSFQS----- 426
Query: 104 PGIILLTRVDCASKINIKLCDKFSVGHYPMLFWGPPPKFVGGSWEPKQEKSDIHVIDDAR 163
+++ ++D + N D F V YP L++ + + D R
Sbjct: 427 DADVVIAKLDATA--NDIPTDTFDVQGYPTLYF-------------RSASGKLSQYDGGR 471
Query: 164 TADRLLNWINK 174
T + ++ +I K
Sbjct: 472 TKEDIIEFIEK 482
>PDA4_MOUSE (P08003) Protein disulfide-isomerase A4 precursor (EC
5.3.4.1) (Protein ERp-72) (ERp72)
Length = 638
Score = 50.8 bits (120), Expect = 8e-06
Identities = 35/132 (26%), Positives = 54/132 (40%), Gaps = 8/132 (6%)
Query: 3 LLYFALFLCTISVSSSATSSSSSSFPGRSILREVHDNDQTGTTDHDYAVELNATNFDAVL 62
+L AL + S+ +S + E D+D + + LN NFD +
Sbjct: 10 VLLLALTQLLAAASAGDAQEDTSDTENATEEEEEEDDDDLEVKEENGVWVLNDGNFDNFV 69
Query: 63 KDTPATFAVVEFFANWCPACRNYKPHYEKVAKLFNGPDAVHPGIILLTRVDCASKINIKL 122
D ++EF+A WC C+ + P YEK+A D I + ++D S L
Sbjct: 70 ADKDTV--LLEFYAPWCGHCKQFAPEYEKIASTLKDNDPP----IAVAKIDATSA--SML 121
Query: 123 CDKFSVGHYPML 134
KF V YP +
Sbjct: 122 ASKFDVSGYPTI 133
Score = 47.8 bits (112), Expect = 7e-05
Identities = 34/102 (33%), Positives = 47/102 (45%), Gaps = 10/102 (9%)
Query: 33 LREVHDNDQTGTTDHDYAVELNATNFDAVLKDTPATFAVVEFFANWCPACRNYKPHYEKV 92
+REV D T + + L NFD V+ + A +VEF+A WC C+ P YEK
Sbjct: 157 VREVSQPDWTPPPE--VTLSLTKDNFDDVVNN--ADIILVEFYAPWCGHCKKLAPEYEKA 212
Query: 93 AKLFNGPDAVHPGIILLTRVDCASKINIKLCDKFSVGHYPML 134
AK + P L +VD + + L +F V YP L
Sbjct: 213 AKELSKRSPPIP----LAKVDATEQTD--LAKRFDVSGYPTL 248
Score = 46.6 bits (109), Expect = 2e-04
Identities = 32/119 (26%), Positives = 57/119 (47%), Gaps = 16/119 (13%)
Query: 58 FDAVLKDTPATFAVVEFFANWCPACRNYKPHYEKVAKLFNGPDAVHPGIILLTRVDCASK 117
FDA++ D P ++EF+A WC C+ +P Y + K + G +++ ++D +
Sbjct: 528 FDAIVMD-PKKDVLIEFYAPWCGHCKQLEPIYTSLGKKYKGQKD-----LVIAKMDATA- 580
Query: 118 INIKLCDKFSVGHYPMLFWGP------PPKFVGGS--WEPKQEKSDIHVIDDARTADRL 168
N D++ V +P +++ P P KF GG+ E + D H +RT + L
Sbjct: 581 -NDITNDQYKVEGFPTIYFAPSGDKKNPIKFEGGNRDLEHLSKFIDEHATKRSRTKEEL 638
>PDI1_CAEEL (Q17967) Protein disulfide-isomerase 1 precursor (EC
5.3.4.1) (PDI 1) (Prolyl 4-hydroxylase beta 1 subunit)
Length = 485
Score = 50.4 bits (119), Expect = 1e-05
Identities = 36/135 (26%), Positives = 57/135 (41%), Gaps = 22/135 (16%)
Query: 46 DHDYAVELNATNFDAVLKDTPATFAVVEFFANWCPACRNYKPHYEKVAKLF--NGPDAVH 103
D + + L +NF+ + F +V+F+A WC C++ P Y++ A L G D
Sbjct: 21 DSENVLVLTESNFEETINGNE--FVLVKFYAPWCVHCKSLAPKYDEAADLLKEEGSD--- 75
Query: 104 PGIILLTRVDCASKINIKLCDKFSVGHYPMLFW---GPPPKFVGG-------SWEPKQEK 153
I L +VD N L KF V YP + + G P K+ GG W K+
Sbjct: 76 ---IKLAKVDATE--NQALASKFEVRGYPTILYFKSGKPTKYTGGRATAQIVDWVKKKSG 130
Query: 154 SDIHVIDDARTADRL 168
+ ++ + L
Sbjct: 131 PTVTTVESVEQLEEL 145
Score = 31.6 bits (70), Expect = 5.2
Identities = 16/51 (31%), Positives = 30/51 (58%), Gaps = 2/51 (3%)
Query: 53 LNATNFDAVLKDTPATFAVVEFFANWCPACRNYKPHYEKVAKLF-NGPDAV 102
L A+NF+ + D T V+F+A WC C+ P ++++A+ + + P+ V
Sbjct: 368 LVASNFNEIALDETKT-VFVKFYAPWCGHCKQLVPVWDELAEKYESNPNVV 417
>PDI2_SCHPO (O13811) Putative protein disulfide-isomerase C17H9.14c
precursor (EC 5.3.4.1)
Length = 359
Score = 50.1 bits (118), Expect = 1e-05
Identities = 38/126 (30%), Positives = 61/126 (48%), Gaps = 21/126 (16%)
Query: 51 VELNATNFDAVLKDTPATFAVVEFFANWCPACRNYKPHYEKVAKLFNGPDAVHPGIILLT 110
VEL++ NFD V+ D +VEF+A+WC C+ P YE + K+F P + ++
Sbjct: 143 VELDSLNFDKVVMDDKKD-VLVEFYADWCGYCKRLAPTYETLGKVFKN----EPNVEIV- 196
Query: 111 RVDCASKINIKLCDKFS-VGHYPMLFWGPPPKFVGGSWEPKQEKSDIHVIDDARTADRLL 169
KIN D F+ +G + P KF PK +K + + R+ + L+
Sbjct: 197 ------KIN---ADVFADIGRLHEVASFPTIKFF-----PKDDKDKPELYEGDRSLESLI 242
Query: 170 NWINKQ 175
+INK+
Sbjct: 243 EYINKK 248
Score = 48.5 bits (114), Expect = 4e-05
Identities = 31/106 (29%), Positives = 54/106 (50%), Gaps = 19/106 (17%)
Query: 70 AVVEFFANWCPACRNYKPHYEKVAKLFNGPDAVHPGIILLTRVDCASKINIKLCDKFSVG 129
A++EF+A WC C++ P YE++ LF + V L+ ++D + ++ DK+ +
Sbjct: 42 ALIEFYATWCGHCKSLAPVYEELGALFEDHNDV-----LIGKIDADTHSDV--ADKYHIT 94
Query: 130 HYPMLFWGPPPKFVGGSWEPKQEKSDIHVIDDARTADRLLNWINKQ 175
+P L W PP GS EP Q +AR D L +++++
Sbjct: 95 GFPTLIWFPP----DGS-EPVQ-------YSNARDVDSLTQFVSEK 128
>PDI_MAIZE (P52588) Protein disulfide-isomerase precursor (EC
5.3.4.1) (PDI)
Length = 513
Score = 49.7 bits (117), Expect = 2e-05
Identities = 27/97 (27%), Positives = 45/97 (45%), Gaps = 6/97 (6%)
Query: 38 DNDQTGTTDHDYAVELNATNFDAVLKDTPATFAVVEFFANWCPACRNYKPHYEKVAKLFN 97
+ + + + + L+ +FD + P F VVEF+A WC C+ P YE AK
Sbjct: 24 EEEPAAAAEGEAVLTLDVDSFDEAVAKHP--FMVVEFYAPWCGHCKKLAPEYENAAKAL- 80
Query: 98 GPDAVHPGIILLTRVDCASKINIKLCDKFSVGHYPML 134
+ H I+L +VD + N L K+ + +P +
Sbjct: 81 ---SKHDPPIVLAKVDANEEKNRPLATKYEIQGFPTI 114
Score = 37.7 bits (86), Expect = 0.072
Identities = 32/154 (20%), Positives = 60/154 (38%), Gaps = 28/154 (18%)
Query: 33 LREVHDNDQTGTTDHDYAVELNATNFDAVLKDTPATFA-------VVEFFANWCPACRNY 85
L+E D T + + E+N V+ D F ++EF+A WC C+
Sbjct: 355 LKEYFDGKLTPFRNSEPIPEVNNEPVKVVVADNVHDFVFKSGKNVLIEFYAPWCGHCKKL 414
Query: 86 KPHYEKVAKLFNGPDAVHPGIILLTRVDCASKINIKLCDKFSVGHYPMLFWGPPPKFVGG 145
P ++ A + V ++ ++D + + +F V YP L++ P
Sbjct: 415 APILDEAATTLQSDEEV-----VIAKMDATAN---DVPSEFDVQGYPTLYFVTP------ 460
Query: 146 SWEPKQEKSDIHVIDDARTADRLLNWINKQMSSS 179
+ D RTAD ++++I K ++
Sbjct: 461 -------SGKVTSYDSGRTADDIVDFIKKSKETA 487
>PDA4_RAT (P38659) Protein disulfide-isomerase A4 precursor (EC
5.3.4.1) (Protein ERp-72) (ERp72) (Calcium-binding
protein 2) (CaBP2)
Length = 643
Score = 49.7 bits (117), Expect = 2e-05
Identities = 35/139 (25%), Positives = 59/139 (42%), Gaps = 15/139 (10%)
Query: 3 LLYFALFLCTISVSSSATSSSSSSFPGRSILREVHDNDQTGTTDHDYAVE-------LNA 55
LL L L + ++SA + + + + + + ++ + D V+ LN
Sbjct: 8 LLVLLLALTQLLAAASAEDAHEDASDSENPIEDDDEEEEDEEDEDDLEVKEENGVWVLND 67
Query: 56 TNFDAVLKDTPATFAVVEFFANWCPACRNYKPHYEKVAKLFNGPDAVHPGIILLTRVDCA 115
NFD + D ++EF+A WC C+ + P YEK+A D I + ++D
Sbjct: 68 ENFDNFVADKDTV--LLEFYAPWCGHCKQFAPEYEKIASTLKDNDPP----IAVAKIDAT 121
Query: 116 SKINIKLCDKFSVGHYPML 134
S L KF V YP +
Sbjct: 122 SA--SMLASKFDVSGYPTI 138
Score = 47.4 bits (111), Expect = 9e-05
Identities = 34/102 (33%), Positives = 47/102 (45%), Gaps = 10/102 (9%)
Query: 33 LREVHDNDQTGTTDHDYAVELNATNFDAVLKDTPATFAVVEFFANWCPACRNYKPHYEKV 92
+REV D T + + L NFD V+ + A +VEF+A WC C+ P YEK
Sbjct: 162 VREVSQPDWTPPPE--VTLTLTKENFDDVVNN--ADIILVEFYAPWCGHCKKLAPEYEKA 217
Query: 93 AKLFNGPDAVHPGIILLTRVDCASKINIKLCDKFSVGHYPML 134
AK + P L +VD + + L +F V YP L
Sbjct: 218 AKELSKRSPPIP----LAKVDATEQTD--LAKRFDVSGYPTL 253
Score = 47.0 bits (110), Expect = 1e-04
Identities = 32/119 (26%), Positives = 57/119 (47%), Gaps = 16/119 (13%)
Query: 58 FDAVLKDTPATFAVVEFFANWCPACRNYKPHYEKVAKLFNGPDAVHPGIILLTRVDCASK 117
FDA++ D P ++EF+A WC C+ +P Y + K + G +++ ++D +
Sbjct: 533 FDAIVMD-PKKDVLIEFYAPWCGHCKQLEPVYTSLGKKYKGQKD-----LVIAKMDATA- 585
Query: 118 INIKLCDKFSVGHYPMLFWGP------PPKFVGGS--WEPKQEKSDIHVIDDARTADRL 168
N D++ V +P +++ P P KF GG+ E + D H +RT + L
Sbjct: 586 -NDITNDRYKVEGFPTIYFAPSGDKKNPIKFEGGNRDLEHLSKFIDEHATKRSRTKEEL 643
>PDA4_HUMAN (P13667) Protein disulfide-isomerase A4 precursor (EC
5.3.4.1) (Protein ERp-72) (ERp72)
Length = 645
Score = 49.7 bits (117), Expect = 2e-05
Identities = 35/102 (34%), Positives = 48/102 (46%), Gaps = 10/102 (9%)
Query: 33 LREVHDNDQTGTTDHDYAVELNATNFDAVLKDTPATFAVVEFFANWCPACRNYKPHYEKV 92
+REV D T + + L NFD V+ D A +VEF+A WC C+ P YEK
Sbjct: 164 VREVSQPDWTPPPE--VTLVLTKENFDEVVND--ADIILVEFYAPWCGHCKKLAPEYEKA 219
Query: 93 AKLFNGPDAVHPGIILLTRVDCASKINIKLCDKFSVGHYPML 134
AK + P L +VD ++ + L +F V YP L
Sbjct: 220 AKELSKRSPPIP----LAKVDATAETD--LAKRFDVSGYPTL 255
Score = 48.5 bits (114), Expect = 4e-05
Identities = 27/97 (27%), Positives = 44/97 (44%), Gaps = 8/97 (8%)
Query: 38 DNDQTGTTDHDYAVELNATNFDAVLKDTPATFAVVEFFANWCPACRNYKPHYEKVAKLFN 97
+ D + + + LN NFD + D ++EF+A WC C+ + P YEK+A +
Sbjct: 52 EEDDLEVKEENGVLVLNDANFDNFVADKDTV--LLEFYAPWCGHCKQFAPEYEKIANILK 109
Query: 98 GPDAVHPGIILLTRVDCASKINIKLCDKFSVGHYPML 134
D P + ++D S L +F V YP +
Sbjct: 110 DKDPPIP----VAKIDATSA--SVLASRFDVSGYPTI 140
Score = 47.0 bits (110), Expect = 1e-04
Identities = 26/94 (27%), Positives = 48/94 (50%), Gaps = 14/94 (14%)
Query: 58 FDAVLKDTPATFAVVEFFANWCPACRNYKPHYEKVAKLFNGPDAVHPGIILLTRVDCASK 117
FD+++ D P ++EF+A WC C+ +P Y +AK + G +++ ++D +
Sbjct: 535 FDSIVMD-PKKDVLIEFYAPWCGHCKQLEPVYNSLAKKYKGQKG-----LVIAKMDATA- 587
Query: 118 INIKLCDKFSVGHYPMLFWGP------PPKFVGG 145
N D++ V +P +++ P P KF GG
Sbjct: 588 -NDVPSDRYKVEGFPTIYFAPSGDKKNPVKFEGG 620
>PDA4_CAEEL (P34329) Probable protein disulfide-isomerase A4
precursor (EC 5.3.4.1) (ERp-72 homolog)
Length = 618
Score = 48.1 bits (113), Expect = 5e-05
Identities = 34/109 (31%), Positives = 52/109 (47%), Gaps = 16/109 (14%)
Query: 31 SILREVHD--NDQTGTTDHDYAVELNATNFDAVLKDTPATFAVVEFFANWCPACRNYKPH 88
S +R D +D+ + V L NFDA LK P+ +V+F+A WC C++ P
Sbjct: 17 SAVRSTEDASDDELNYEMDEGVVVLTDKNFDAFLKKNPSV--LVKFYAPWCGHCKHLAPE 74
Query: 89 YEKVAKLFNGPDAVHPGIILLTRVDCASKINIKLCDKFSVGHYPML-FW 136
YEK + + P L +VD + + +L +F + YP L FW
Sbjct: 75 YEKASSKVSIP---------LAKVD--ATVETELGKRFEIQGYPTLKFW 112
Score = 40.0 bits (92), Expect = 0.015
Identities = 26/84 (30%), Positives = 38/84 (44%), Gaps = 8/84 (9%)
Query: 51 VELNATNFDAVLKDTPATFAVVEFFANWCPACRNYKPHYEKVAKLFNGPDAVHPGIILLT 110
V L NFD + + +VEF+A WC C+ P YEK A+ + + L
Sbjct: 150 VTLTTENFDDFISNNE--LVLVEFYAPWCGHCKKLAPEYEKAAQKLKAQGSK----VKLG 203
Query: 111 RVDCASKINIKLCDKFSVGHYPML 134
+VD + I L K+ V YP +
Sbjct: 204 KVD--ATIEKDLGTKYGVSGYPTM 225
Score = 37.7 bits (86), Expect = 0.072
Identities = 21/89 (23%), Positives = 46/89 (51%), Gaps = 14/89 (15%)
Query: 56 TNFDAVLKDTPATFAVVEFFANWCPACRNYKPHYEKVAKLFNGPDAVHPGIILLTRVDCA 115
+NFD ++ D ++EF+A WC C++++ Y ++A+ P ++L
Sbjct: 507 SNFDKIVNDESKD-VLIEFYAPWCGHCKSFESKYVELAQALK---KTQPNVVL------- 555
Query: 116 SKINIKLCD---KFSVGHYPMLFWGPPPK 141
+K++ + D +F+V +P +++ P K
Sbjct: 556 AKMDATINDAPSQFAVEGFPTIYFAPAGK 584
Database: sprot
Posted date: Nov 25, 2004 10:54 AM
Number of letters in database: 59,974,054
Number of sequences in database: 164,201
Lambda K H
0.320 0.135 0.423
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 64,299,743
Number of Sequences: 164201
Number of extensions: 2752777
Number of successful extensions: 7342
Number of sequences better than 10.0: 115
Number of HSP's better than 10.0 without gapping: 73
Number of HSP's successfully gapped in prelim test: 42
Number of HSP's that attempted gapping in prelim test: 7194
Number of HSP's gapped (non-prelim): 171
length of query: 517
length of database: 59,974,054
effective HSP length: 115
effective length of query: 402
effective length of database: 41,090,939
effective search space: 16518557478
effective search space used: 16518557478
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 68 (30.8 bits)
Medicago: description of AC144731.8