BLAST2 result
BLASTP 2.2.2 [Dec-14-2001]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= AC144720.2 + phase: 0 /pseudo
(552 letters)
Database: sprot
164,201 sequences; 59,974,054 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
AVT1_YEAST (P47082) Vacuolar amino acid transporter 1 160 8e-39
VIAA_MACFA (Q95KE2) Vesicular inhibitory amino acid transporter ... 102 2e-21
VIAA_HUMAN (Q9H598) Vesicular inhibitory amino acid transporter ... 102 3e-21
UN47_CAEEL (P34579) Vesicular GABA transporter (Uncoordinated pr... 100 1e-20
VIAA_MOUSE (O35633) Vesicular inhibitory amino acid transporter ... 99 3e-20
VIAA_RAT (O35458) Vesicular inhibitory amino acid transporter (G... 99 4e-20
AVT4_YEAST (P50944) Vacuolar amino acid transporter 4 80 1e-14
YAN9_SCHPO (Q10074) Hypothetical protein C3H1.09c in chromosome I 76 3e-13
S383_HUMAN (Q99624) System N amino acid transporter 1 (SN1) (N-s... 70 1e-11
S383_RAT (Q9JHZ9) System N amino acid transporter 1 (SN1) (N-sys... 69 2e-11
S383_MOUSE (Q9DCP2) System N amino acid transporter 1 (SN1) (N-s... 69 2e-11
AVT3_YEAST (P36062) Vacuolar amino acid transporter 3 65 4e-10
S361_HUMAN (Q7Z2H8) Proton-coupled amino acid transporter 1 (Pro... 65 6e-10
S361_MOUSE (Q8K4D3) Proton-coupled amino acid transporter 1 (Pro... 64 1e-09
S361_RAT (Q924A5) Proton-coupled amino acid transporter 1 (Proto... 62 3e-09
AVT6_YEAST (P40074) Vacuolar amino acid transporter 6 58 7e-08
YMJ2_CAEEL (P34479) Hypothetical protein F59B2.2 in chromosome III 57 1e-07
AVT2_YEAST (P39981) Vacuolar amino acid transporter 2 53 2e-06
AVT5_YEAST (P38176) Vacuolar amino acid transporter 5 50 2e-05
AVT7_YEAST (P40501) Vacuolar amino acid transporter 7 44 0.001
>AVT1_YEAST (P47082) Vacuolar amino acid transporter 1
Length = 602
Score = 160 bits (405), Expect = 8e-39
Identities = 119/366 (32%), Positives = 182/366 (49%), Gaps = 42/366 (11%)
Query: 156 QAVLNGINVLCGVGILSTPYAAKEGGW-LGLSILFIFGILSFYTGLLLRSCLDSEPGLET 214
Q + N INVL G+G+L+ P K GW +GL++L IF + +F T LL CLD++P L +
Sbjct: 212 QTIFNSINVLIGIGLLALPLGLKYAGWVIGLTMLAIFALATFCTAELLSRCLDTDPTLIS 271
Query: 215 YPDIGQAAFGTAGRIAISIVLYVELYGCCIEYIILEGDNLASLFPNAYLNLGGIELNPQT 274
Y D+G AAFGT GR IS + ++L G + +IL GD+L +LFP T
Sbjct: 272 YADLGYAAFGTKGRALISALFTLDLLGSGVSLVILFGDSLNALFPQ----------YSTT 321
Query: 275 LFAVVAALAVLPTVWLRDLSVLSYISAGGVIASVLVVLCLLWIGIEDVG--------FQR 326
F +V+ V P V++ LSVLS IS G++++ VL + G+ +
Sbjct: 322 FFKIVSFFIVTPPVFI-PLSVLSNISLLGILSTTGTVLVICCCGLYKSSSPGSLVNPMET 380
Query: 327 SGTTLNLGTLPVAIGLYGYCYSGHAVFPNIYTSMAKPNQFPAVLVACFGVCTLLYAGGAV 386
S ++L L ++IGL C+ GHAVFPN+ T M P++F L + + ++ G AV
Sbjct: 381 SMWPIDLKHLCLSIGLLSACWGGHAVFPNLKTDMRHPDKFKDCLKTTYKITSVTDIGTAV 440
Query: 387 MGYKMFGEDTLSQFTLNL------PQDLVATKIAVWTTVVNPFTKYALTISPVAMSLEEL 440
+G+ MFG + T N+ P+ + A+ T + P K L P+ L+ L
Sbjct: 441 IGFLMFGNLVKDEITKNVLLTEGYPKFVYGLISALMTII--PIAKTPLNARPIVSVLDVL 498
Query: 441 IPANH---AKSYL-------FSIFIRTGLVFSTLVIGLSVPFF---VALCYGKLAIT-CL 486
+ H A S + +F R + ++I ++ P F +A L T CL
Sbjct: 499 MNVQHIDEAASAIKRRAAKGLQVFNRIFINVVFVLIAINFPEFDKIIAFLGAGLCFTICL 558
Query: 487 IILCRF 492
I+ C F
Sbjct: 559 ILPCWF 564
>VIAA_MACFA (Q95KE2) Vesicular inhibitory amino acid transporter
(GABA and glycine transporter) (Vesicular GABA
transporter) (QccE-21148)
Length = 525
Score = 102 bits (255), Expect = 2e-21
Identities = 90/393 (22%), Positives = 174/393 (43%), Gaps = 42/393 (10%)
Query: 112 PTEEEKHQRRSSHTLLPPLSRRSSLLKKESKVSHEVPSRHCSFGQAVLNGINVLCGVGIL 171
P E + H +R S LPP + + H+ P + +A N N + G+ +L
Sbjct: 78 PVEGDIHYQRGSGAPLPPSGSKDQVGAGGEFGGHDKPK--ITAWEAGWNVTNAIQGMFVL 135
Query: 172 STPYAAKEGGWLGLSILFIFGILSFYTGLLLRSCL--DSEPG-----LETYPDIGQAA-- 222
PYA GG+LGL ++ ++ YTG +L +CL ++E G ++Y I A
Sbjct: 136 GLPYAILHGGYLGLFLIIFAAVVCCYTGKILIACLYEENEDGEVVRVRDSYVAIANACCA 195
Query: 223 --FGTAGRIAISIVLYVELYGCCIEYIILEGDNLASLFPNAYLNLGGIELNPQTLFAVVA 280
F T G +++ +EL CI Y+++ G+ + + FP ++ Q ++++A
Sbjct: 196 PRFPTLGGRVVNVAQIIELVMTCILYVVVSGNLMYNSFPGLPVS--------QKSWSIIA 247
Query: 281 ALAVLPTVWLRDLSVLSYIS-----AGGVIASVLVVLCLLWIGIEDVGFQRSGTTLNLGT 335
+LP +L++L +S S A VI +++ CL D +++ +++
Sbjct: 248 TAVLLPCAFLKNLKAVSKFSLLCTLAHFVINILVIAYCL--SRARDWAWEKVKFYIDVKK 305
Query: 336 LPVAIGLYGYCYSGHAVFPNIYTSMAKPNQFPAVLVACFGVCTLLYAGGAVMGYKMFGED 395
P++IG+ + Y+ P++ +M +P++F ++ +L A++ Y + ++
Sbjct: 306 FPISIGIIVFSYTSQIFLPSLEGNMQQPSEFHCMMNWTHIAACVLKGLFALVAYLTWADE 365
Query: 396 TLSQFTLNLPQDLVATKIAVWTTVVNPFTKYALTISPVAMSLEELIPANHAKSYL----- 450
T T NLP + A + V Y L LE+ + ++++
Sbjct: 366 TKEVITDNLPGSIRA--VVNIFLVAKALLSYPLPFFAAVEVLEKSLFQEGSRAFFPACYG 423
Query: 451 -------FSIFIRTGLVFSTLVIGLSVPFFVAL 476
+ + +R LV TL++ + VP F L
Sbjct: 424 GDGRLKSWGLTLRCALVVFTLLMAIYVPHFALL 456
>VIAA_HUMAN (Q9H598) Vesicular inhibitory amino acid transporter
(GABA and glycine transporter) (Vesicular GABA
transporter) (hVIAAT)
Length = 525
Score = 102 bits (254), Expect = 3e-21
Identities = 90/393 (22%), Positives = 174/393 (43%), Gaps = 42/393 (10%)
Query: 112 PTEEEKHQRRSSHTLLPPLSRRSSLLKKESKVSHEVPSRHCSFGQAVLNGINVLCGVGIL 171
P E + H +R S LPP + + H+ P + +A N N + G+ +L
Sbjct: 78 PVEGDIHYQRGSGAPLPPSGSKDQVGGGGEFGGHDKPK--ITAWEAGWNVTNAIQGMFVL 135
Query: 172 STPYAAKEGGWLGLSILFIFGILSFYTGLLLRSCL--DSEPG-----LETYPDIGQAA-- 222
PYA GG+LGL ++ ++ YTG +L +CL ++E G ++Y I A
Sbjct: 136 GLPYAILHGGYLGLFLIIFAAVVCCYTGKILIACLYEENEDGEVVRVRDSYVAIANACCA 195
Query: 223 --FGTAGRIAISIVLYVELYGCCIEYIILEGDNLASLFPNAYLNLGGIELNPQTLFAVVA 280
F T G +++ +EL CI Y+++ G+ + + FP ++ Q ++++A
Sbjct: 196 PRFPTLGGRVVNVAQIIELVMTCILYVVVSGNLMYNSFPGLPVS--------QKSWSIIA 247
Query: 281 ALAVLPTVWLRDLSVLSYIS-----AGGVIASVLVVLCLLWIGIEDVGFQRSGTTLNLGT 335
+LP +L++L +S S A VI +++ CL D +++ +++
Sbjct: 248 TAVLLPCAFLKNLKAVSKFSLLCTLAHFVINILVIAYCL--SRARDWAWEKVKFYIDVKK 305
Query: 336 LPVAIGLYGYCYSGHAVFPNIYTSMAKPNQFPAVLVACFGVCTLLYAGGAVMGYKMFGED 395
P++IG+ + Y+ P++ +M +P++F ++ +L A++ Y + ++
Sbjct: 306 FPISIGIIVFSYTSQIFLPSLEGNMQQPSEFHCMMNWTHIAACVLKGLFALVAYLTWADE 365
Query: 396 TLSQFTLNLPQDLVATKIAVWTTVVNPFTKYALTISPVAMSLEELIPANHAKSYL----- 450
T T NLP + A + V Y L LE+ + ++++
Sbjct: 366 TKEVITDNLPGSIRA--VVNIFLVAKALLSYPLPFFAAVEVLEKSLFQEGSRAFFPACYS 423
Query: 451 -------FSIFIRTGLVFSTLVIGLSVPFFVAL 476
+ + +R LV TL++ + VP F L
Sbjct: 424 GDGRLKSWGLTLRCALVVFTLLMAIYVPHFALL 456
>UN47_CAEEL (P34579) Vesicular GABA transporter (Uncoordinated
protein 47) (Protein unc-47)
Length = 486
Score = 100 bits (249), Expect = 1e-20
Identities = 100/395 (25%), Positives = 166/395 (41%), Gaps = 43/395 (10%)
Query: 111 QPTEEEKHQRRSSHTLLPPLS--------RRSSLLKKESKVS--HEVPSRHCSFGQAVLN 160
QP E H L P+ ++ + K+E H S S QA N
Sbjct: 38 QPQTGESGSNPPPHDRLEPIQESVVSEQPQKDDINKQEEAKDDGHGEASEPISALQAAWN 97
Query: 161 GINVLCGVGILSTPYAAKEGGWLGLSILFIFGILSFYTGLLLRSCLDSEPGLE---TYPD 217
N + G+ I+ P A K GGW + + + ++TG+LL CL E G++ TY +
Sbjct: 98 VTNAIQGMFIVGLPIAVKVGGWWSIGAMVGVAYVCYWTGVLLIECL-YENGVKKRKTYRE 156
Query: 218 IGQAAFGTAGRIAISIVLYVELYGCCIEYIILEGDNLASLFPNAYLNLGGIELNPQTLFA 277
I G+ ++ L EL CI Y++L D L S FP+ + +
Sbjct: 157 IADFYKPGFGKWVLAAQL-TELLSTCIIYLVLAADLLQSCFPSV----------DKAGWM 205
Query: 278 VVAALAVLPTVWLRDLSVLSYISAGGVIASVLVVLCLLWIGIEDVG---FQRSGTTLNLG 334
++ + ++L +L DL ++S +S I+ ++V L ++ + V F +LN+
Sbjct: 206 MITSASLLTCSFLDDLQIVSRLSFFNAISHLIVNLIMVLYCLSFVSQWSFSTITFSLNIN 265
Query: 335 TLPVAIGLYGYCYSGHAVFPNIYTSMAKPNQFPAVLVACFGVCTLLYAGGAVMGYKMFGE 394
TLP +G+ + Y+ H PN+ +M P QF +L + ++G+ FGE
Sbjct: 266 TLPTIVGMVVFGYTSHIFLPNLEGNMKNPAQFNVMLKWSHIAAAVFKVVFGMLGFLTFGE 325
Query: 395 DTLSQFTLNLPQDLVATKIAV-WTTVVNPFTKYALTISPVAMSLEELIPANHAKSYLFSI 453
T + + +LP + KI V VV Y L L+ + + ++ S
Sbjct: 326 LTQEEISNSLPNQ--SFKILVNLILVVKALLSYPLPFYAAVQLLKNNLFLGYPQTPFTSC 383
Query: 454 F------------IRTGLVFSTLVIGLSVPFFVAL 476
+ +R LV TL + LSVP+ V L
Sbjct: 384 YSPDKSLREWAVTLRIILVLFTLFVALSVPYLVEL 418
>VIAA_MOUSE (O35633) Vesicular inhibitory amino acid transporter
(GABA and glycine transporter) (Vesicular GABA
transporter) (mVIAAT) (mVGAT)
Length = 525
Score = 99.0 bits (245), Expect = 3e-20
Identities = 89/393 (22%), Positives = 174/393 (43%), Gaps = 42/393 (10%)
Query: 112 PTEEEKHQRRSSHTLLPPLSRRSSLLKKESKVSHEVPSRHCSFGQAVLNGINVLCGVGIL 171
P E + H +R L P S+ ++ H+ P + +A N N + G+ +L
Sbjct: 78 PVEGDIHYQRGGAPLPPSGSKDQAVGAGGEFGGHDKPK--ITAWEAGWNVTNAIQGMFVL 135
Query: 172 STPYAAKEGGWLGLSILFIFGILSFYTGLLLRSCL--DSEPG-----LETYPDIGQAA-- 222
PYA GG+LGL ++ ++ YTG +L +CL ++E G ++Y I A
Sbjct: 136 GLPYAILHGGYLGLFLIIFAAVVCCYTGKILIACLYEENEDGEVVRVRDSYVAIANACCA 195
Query: 223 --FGTAGRIAISIVLYVELYGCCIEYIILEGDNLASLFPNAYLNLGGIELNPQTLFAVVA 280
F T G +++ +EL CI Y+++ G+ + + FP ++ Q ++++A
Sbjct: 196 PRFPTLGGRVVNVAQIIELVMTCILYVVVSGNLMYNSFPGLPVS--------QKSWSIIA 247
Query: 281 ALAVLPTVWLRDLSVLSYIS-----AGGVIASVLVVLCLLWIGIEDVGFQRSGTTLNLGT 335
+LP +L++L +S S A VI +++ CL D +++ +++
Sbjct: 248 TAVLLPCAFLKNLKAVSKFSLLCTLAHFVINILVIAYCL--SRARDWAWEKVKFYIDVKK 305
Query: 336 LPVAIGLYGYCYSGHAVFPNIYTSMAKPNQFPAVLVACFGVCTLLYAGGAVMGYKMFGED 395
P++IG+ + Y+ P++ +M +P++F ++ +L A++ Y + ++
Sbjct: 306 FPISIGIIVFSYTSQIFLPSLEGNMQQPSEFHCMMNWTHIAACVLKGLFALVAYLTWADE 365
Query: 396 TLSQFTLNLPQDLVATKIAVWTTVVNPFTKYALTISPVAMSLEELIPANHAKSYL----- 450
T T NLP + A + V Y L LE+ + ++++
Sbjct: 366 TKEVITDNLPGSIRA--VVNLFLVAKALLSYPLPFFAAVEVLEKSLFQEGSRAFFPACYG 423
Query: 451 -------FSIFIRTGLVFSTLVIGLSVPFFVAL 476
+ + +R LV TL++ + VP F L
Sbjct: 424 GDGRLKSWGLTLRCALVVFTLLMAIYVPHFALL 456
>VIAA_RAT (O35458) Vesicular inhibitory amino acid transporter (GABA
and glycine transporter) (Vesicular GABA transporter)
(rGVAT)
Length = 525
Score = 98.6 bits (244), Expect = 4e-20
Identities = 89/393 (22%), Positives = 174/393 (43%), Gaps = 42/393 (10%)
Query: 112 PTEEEKHQRRSSHTLLPPLSRRSSLLKKESKVSHEVPSRHCSFGQAVLNGINVLCGVGIL 171
P E + H +R L P S+ ++ H+ P + +A N N + G+ +L
Sbjct: 78 PVEGDIHYQRGGAPLPPSGSKDQAVGAGGEFGGHDKPK--ITAWEAGWNVTNAIQGMFVL 135
Query: 172 STPYAAKEGGWLGLSILFIFGILSFYTGLLLRSCL--DSEPG-----LETYPDIGQAA-- 222
PYA GG+LGL ++ ++ YTG +L +CL ++E G ++Y I A
Sbjct: 136 GLPYAILHGGYLGLFLIIFAAVVCCYTGKILIACLYEENEDGEVVRVRDSYVAIANACCA 195
Query: 223 --FGTAGRIAISIVLYVELYGCCIEYIILEGDNLASLFPNAYLNLGGIELNPQTLFAVVA 280
F T G +++ +EL CI Y+++ G+ + + FP ++ Q ++++A
Sbjct: 196 PRFPTLGGRVVNVAQIIELVMTCILYVVVSGNLMYNSFPGLPVS--------QKSWSIIA 247
Query: 281 ALAVLPTVWLRDLSVLSYIS-----AGGVIASVLVVLCLLWIGIEDVGFQRSGTTLNLGT 335
+LP +L++L +S S A VI +++ CL D +++ +++
Sbjct: 248 TAVLLPCAFLKNLKAVSKFSLLCTLAHFVINILVIAYCL--SRARDWAWEKVKFYIDVKK 305
Query: 336 LPVAIGLYGYCYSGHAVFPNIYTSMAKPNQFPAVLVACFGVCTLLYAGGAVMGYKMFGED 395
P++IG+ + Y+ P++ +M +P++F ++ +L A++ Y + ++
Sbjct: 306 FPISIGIIVFSYTSQIFLPSLEGNMQQPSEFHCMMNWTHIAACVLKGLFALVAYLTWADE 365
Query: 396 TLSQFTLNLPQDLVATKIAVWTTVVNPFTKYALTISPVAMSLEELIPANHAKSYL----- 450
T T NLP + A + V Y L LE+ + ++++
Sbjct: 366 TKEVITDNLPGSIRA--VVNIFLVAKALLSYPLPFFAAVEVLEKSLFQEGSRAFFPACYG 423
Query: 451 -------FSIFIRTGLVFSTLVIGLSVPFFVAL 476
+ + +R LV TL++ + VP F L
Sbjct: 424 GDGRLKSWGLTLRCALVVFTLLMAIYVPHFALL 456
>AVT4_YEAST (P50944) Vacuolar amino acid transporter 4
Length = 713
Score = 80.5 bits (197), Expect = 1e-14
Identities = 78/298 (26%), Positives = 128/298 (42%), Gaps = 22/298 (7%)
Query: 122 SSHTLLPPLSRRSSLLKKESKVSHEVPSRH--CSFGQAVLNGINVLCGVGILSTPYAAKE 179
SS+ ++ RS+LL + + +PS S + L + G G+L P A
Sbjct: 266 SSNMMIRGEDERSALLSRPDHMK-VLPSAKGTTSTKKVFLILLKSFIGTGVLFLPNAFHN 324
Query: 180 GG-WLGLSILFIFGILSFYTGLLLRSCLDSEPGLETYPDIGQAAFGTAGRIAISIVLYVE 238
GG + +S+L FGI S++ +L S G+ ++ DIG +G RI I L +
Sbjct: 325 GGLFFSVSMLAFFGIYSYWCYYILVQA-KSSCGVSSFGDIGLKLYGPWMRIIILFSLVIT 383
Query: 239 LYGCCIEYIILEGDNLASLFPNAYLNLGGIELNPQTLFAVVAALAVLPTVWLRDLSVLS- 297
G Y+I NL + N + + + P + V + +P ++R++S LS
Sbjct: 384 QVGFSGAYMIFTAKNLQAFLDNVF----HVGVLPLSYLMVFQTIIFIPLSFIRNISKLSL 439
Query: 298 -------YISAGGVIASVLVVLCLLWIGIEDVGFQRSGTT--LNLGTLPVAIGLYGYCYS 348
+I AG VI + L + + +G G LN + IG + +
Sbjct: 440 PSLLANFFIMAGLVIVIIFTAKRLFF---DLMGTPAMGVVYGLNADRWTLFIGTAIFAFE 496
Query: 349 GHAVFPNIYTSMAKPNQFPAVLVACFGVCTLLYAGGAVMGYKMFGEDTLSQFTLNLPQ 406
G + + SM P +FP VL T+L+ A +GY +G + + LNLPQ
Sbjct: 497 GIGLIIPVQDSMRNPEKFPLVLALVILTATILFISIATLGYLAYGSNVQTVILLNLPQ 554
>YAN9_SCHPO (Q10074) Hypothetical protein C3H1.09c in chromosome I
Length = 656
Score = 75.9 bits (185), Expect = 3e-13
Identities = 79/295 (26%), Positives = 120/295 (39%), Gaps = 29/295 (9%)
Query: 124 HTLLPPLSRRSSLLKKESKVSHEVPSRHCSFGQAVLNGINVLCGVGILSTPYAAKEGGWL 183
H+ +P S + L+ + + + P + S G+AVL + G G+L P A K GG +
Sbjct: 250 HSTVP--SEQEPLISRHGRYKLQTPG-NASNGKAVLLLLKSFVGTGVLFLPKAFKLGGLV 306
Query: 184 GLSI-LFIFGILSFYTGLLLRSCLDSEPGLETYPDIGQAAFGTAGRIAISIVLYVELYGC 242
S L I G+LS LLL PG ++ DIG +G R AI + V G
Sbjct: 307 FSSATLLIVGVLSHICFLLLIQTRMKVPG--SFGDIGGTLYGPHMRFAILASIVVSQIGF 364
Query: 243 CIEYIILEGDNLASLFPNAYLNLGGIELNPQTLFAVVAALAVLPTVWLRDLSVLSYISAG 302
YI L + L +F + L +P +R +S LS A
Sbjct: 365 SSAYISFVASTLQACVKVISTTHREYHL---AVFIFIQFLVFVPLSLVRKISKLS---AT 418
Query: 303 GVIASVLVVLCLLWI-----------GIEDVGFQRSGTTLNLGTLPVAIGLYGYCYSGHA 351
+IA V ++L +L++ GI DV N + IG+ + Y G
Sbjct: 419 ALIADVFILLGILYLYFWDVITLATKGIADVAM------FNKTDFSLFIGVAIFTYEGIC 472
Query: 352 VFPNIYTSMAKPNQFPAVLVACFGVCTLLYAGGAVMGYKMFGEDTLSQFTLNLPQ 406
+ I MAKP P +L +LL+ ++ Y FG + LN+P+
Sbjct: 473 LILPIQEQMAKPKNLPKLLTGVMAAISLLFISIGLLSYAAFGSKVKTVVILNMPE 527
>S383_HUMAN (Q99624) System N amino acid transporter 1 (SN1)
(N-system amino acid transporter 1) (Solute carrier
family 38, member 3)
Length = 504
Score = 70.5 bits (171), Expect = 1e-11
Identities = 105/443 (23%), Positives = 174/443 (38%), Gaps = 79/443 (17%)
Query: 96 RHTPEVLPSVTKPLIQPTEEEKHQRRSSHTLLPPLSRRSSLLKKESKVSHEVPSR-HCSF 154
+H+ +LP +T P+ E R + +S L K SK H SF
Sbjct: 17 KHSEGLLPVIT-PMAGNQRVEDPARSC-------MEGKSFLQKSPSKEPHFTDFEGKTSF 68
Query: 155 GQAVLNGINVLCGVGILSTPYA-AKEGGWLGLSILFIFGILSFYT-GLLLRSCLDSEPGL 212
G +V N N + G GIL YA A G L L +L +LS Y+ LLL+S G+
Sbjct: 69 GMSVFNLSNAIMGSGILGLAYAMANTGIILFLFLLTAVALLSSYSIHLLLKS--SGVVGI 126
Query: 213 ETYPDIGQAAFGTAGRIAISIVLYVELYGCCIEYIILEGDNLASLFPNAYLNL----GGI 268
Y +G AFGT G++A ++ + ++ G Y+ + L L +LNL
Sbjct: 127 RAYEQLGYRAFGTPGKLAAALAITLQNIGAMSSYLYIIKSEL-PLVIQTFLNLEEKTSDW 185
Query: 269 ELNPQTLFAVVAALAVLPTVWLRDLSVLSYISAGGVIASVLVVLCLLW------------ 316
+N L +V+ +LP +R L L Y S + V ++ +++
Sbjct: 186 YMNGNYLVILVSVTIILPLALMRQLGYLGYSSGFSLSCMVFFLIAVIYKKFHVPCPLPPN 245
Query: 317 ------------IGIEDVGFQ----------RSGTTLNLGTLPVAIGLYGYCYSGHAVFP 354
I E V Q S TLN T I + + + H
Sbjct: 246 FNNTTGNFSHVEIVKEKVQLQVEPEASAFCTPSYFTLNSQT-AYTIPIMAFAFVCHPEVL 304
Query: 355 NIYTSMAKPN--QFPAVLVACFGVCTLLYAGGAVMGYKMF----GEDTLSQFTLNLPQD- 407
IYT + P+ + + V ++Y A+ GY F + L ++ P D
Sbjct: 305 PIYTELKDPSKKKMQHISNLSIAVMYIMYFLAALFGYLTFYNGVESELLHTYSKVDPFDV 364
Query: 408 -LVATKIAVWTTVVNPFTKYALTISPVAMSLEELIPANHAKSYLFSIFIRTGL------- 459
++ ++AV T V + + PV ++++++ N S+L + I GL
Sbjct: 365 LILCVRVAVLTAVT---LTVPIVLFPVRRAIQQMLFPNQEFSWLRHVLIAVGLLTCINLL 421
Query: 460 -VFSTLVIGL-------SVPFFV 474
+F+ ++G+ S PF +
Sbjct: 422 VIFAPNILGIFGVIGATSAPFLI 444
>S383_RAT (Q9JHZ9) System N amino acid transporter 1 (SN1) (N-system
amino acid transporter 1) (Solute carrier family 38,
member 3)
Length = 504
Score = 69.3 bits (168), Expect = 2e-11
Identities = 86/386 (22%), Positives = 159/386 (40%), Gaps = 54/386 (13%)
Query: 153 SFGQAVLNGINVLCGVGILSTPYA-AKEGGWLGLSILFIFGILSFYT-GLLLRSCLDSEP 210
SFG +V N N + G GIL YA A G L L +L +LS Y+ LLL+S
Sbjct: 66 SFGMSVFNLSNAIMGSGILGLAYAMANTGIILFLFLLTAVALLSSYSIHLLLKS--SGIV 123
Query: 211 GLETYPDIGQAAFGTAGRIAISIVLYVELYGCCIEYIILEGDNLASLFPNAYLNLGGIE- 269
G+ Y +G AFGT G++A ++ + ++ G Y+ + L L +LNL
Sbjct: 124 GIRAYEQLGYRAFGTPGKLAAALAITLQNIGAMSSYLYIIKSEL-PLVIQTFLNLEKPTP 182
Query: 270 ---LNPQTLFAVVAALAVLPTVWLRDLSVLSYISAGGVIASVLVVLCLLW---------- 316
++ L +V+ + +LP +R L L Y S + V ++ +++
Sbjct: 183 VWYMDGNYLVILVSVIIILPLALMRQLGYLGYSSGFSLSCMVFFLIAVIYKKFQVPCPLA 242
Query: 317 -------------IGIEDVGFQRSGT------------TLNLGTLPVAIGLYGYCYSGHA 351
+ +E+ +S TLN T I + + + H
Sbjct: 243 HNLVNATGNFSHMVVVEEKSQLQSEPDTAEAFCTPSYFTLNSQT-AYTIPIMAFAFVCHP 301
Query: 352 VFPNIYTSMAKPNQFPAVLVACFGVCTL--LYAGGAVMGYKMFGE----DTLSQFTLNLP 405
IYT + P++ ++ + + +Y A+ GY F + + L ++ P
Sbjct: 302 EVLPIYTELKDPSKRKMQHISNLSIAVMYVMYFLAALFGYLTFYDGVESELLHTYSKVDP 361
Query: 406 QDLVATKIAVWTTVVNPFTKYALTISPVAMSLEELIPANHAKSYLFSIFIRTGLVFSTLV 465
D++ + V + T + + PV ++++++ N S+L + I TGL+ +
Sbjct: 362 FDVLILCVRVAVLIAVTLT-VPIVLFPVRRAIQQMLFQNQEFSWLRHVLIATGLLTCINL 420
Query: 466 IGLSVPFFVAL--CYGKLAITCLIIL 489
+ + P + + G + CLI +
Sbjct: 421 LVIFAPNILGIFGIIGATSAPCLIFI 446
>S383_MOUSE (Q9DCP2) System N amino acid transporter 1 (SN1)
(N-system amino acid transporter 1) (Solute carrier
family 38, member 3) (mNAT)
Length = 505
Score = 69.3 bits (168), Expect = 2e-11
Identities = 96/444 (21%), Positives = 173/444 (38%), Gaps = 63/444 (14%)
Query: 96 RHTPEVLP-SVTKPLIQPTEEEKHQRRSSHTLLPPLSRRSSLLKKESKVSHEVPSRHCSF 154
+H +LP V Q TE+ +H L S+ E K S F
Sbjct: 17 KHLEGLLPVGVPTTDTQRTEDTQHCGEGKGFLQKSPSKEPHFTDFEGKTS---------F 67
Query: 155 GQAVLNGINVLCGVGILSTPYA-AKEGGWLGLSILFIFGILSFYT-GLLLRSCLDSEPGL 212
G +V N N + G GIL YA A G L L +L +LS Y+ LLL+S G+
Sbjct: 68 GMSVFNLSNAIMGSGILGLAYAMANTGIILFLFLLTAVALLSSYSIHLLLKS--SGIVGI 125
Query: 213 ETYPDIGQAAFGTAGRIAISIVLYVELYGCCIEYIILEGDNLASLFPNAYLNL----GGI 268
Y +G AFGT G++A ++ + ++ G Y+ + L L +LNL
Sbjct: 126 RAYEQLGYRAFGTPGKLAAALAITLQNIGAMSSYLYIIKSEL-PLVIQTFLNLEKPASVW 184
Query: 269 ELNPQTLFAVVAALAVLPTVWLRDLSVLSYISAGGVIASVLVVLCLLWIGIE---DVGFQ 325
++ L +V+ +LP +R L L Y S + V ++ +++ + +
Sbjct: 185 YMDGNYLVILVSVTIILPLALMRQLGYLGYSSGFSLSCMVFFLIAVIYKKFQVPCPLAHN 244
Query: 326 RSGTTLNLGTLPVA--------------------------------IGLYGYCYSGHAVF 353
+ T N + VA I + + + H
Sbjct: 245 LANATGNFSHMVVAEEKAQLQGEPDTAAEAFCTPSYFTLNSQTAYTIPIMAFAFVCHPEV 304
Query: 354 PNIYTSMAKPNQFPAVLVACFGVCTL--LYAGGAVMGYKMFGE----DTLSQFTLNLPQD 407
IYT + P++ ++ + + +Y A+ GY F + + L ++ P D
Sbjct: 305 LPIYTELKDPSKRKMQHISNLSIAVMYVMYFLAALFGYLTFYDGVESELLHTYSKVDPFD 364
Query: 408 LVATKIAVWTTVVNPFTKYALTISPVAMSLEELIPANHAKSYLFSIFIRTGLVFSTLVIG 467
++ + V + T + + PV ++++++ N S+L + I TGL+ ++
Sbjct: 365 VLILCVRVAVLIAVTLT-VPIVLFPVRRAIQQMLFQNQEFSWLRHVLIATGLLTCINLLV 423
Query: 468 LSVPFFVAL--CYGKLAITCLIIL 489
+ P + + G + CLI +
Sbjct: 424 IFAPNILGIFGIIGATSAPCLIFI 447
>AVT3_YEAST (P36062) Vacuolar amino acid transporter 3
Length = 692
Score = 65.5 bits (158), Expect = 4e-10
Identities = 85/347 (24%), Positives = 138/347 (39%), Gaps = 22/347 (6%)
Query: 114 EEEKHQRRSSHTLLPPLSRRSSLLKKESKVSHEVPSRHCSFGQAVLNGINVLCGVGILST 173
EEE+ + L S+ L H S S +AVL + G G+L
Sbjct: 262 EEEEEEETEEEPEEEALETESTQLVSREHGRHPHKS---STVKAVLLLLKSFVGTGVLFL 318
Query: 174 PYAAKEGGWLGLSILFIFG--ILSFYTGLLLRSCLDSEPGLETYPDIGQAAFGTAGRIAI 231
P A GGW G S L + ++S+ + L + D + G++ Y D+G+ +G + AI
Sbjct: 319 PKAFHNGGW-GFSALCLLSCALISYGCFVSLITTKD-KVGVDGYGDMGRILYGPKMKFAI 376
Query: 232 SIVLYVELYGCCIEYIILEGDNLASLFPNAY-LNLGGIELNPQTLFAVVAALAVLPTVWL 290
+ + G Y + NL N + L G I L +FA V L +P
Sbjct: 377 LSSIALSQIGFSAAYTVFTATNLQVFSENFFHLKPGSISLATY-IFAQV--LIFVPLSLT 433
Query: 291 RDLSVLSYISAGGVIASVLVVLCLLWIGIEDVGF-----QRSGTTL--NLGTLPVAIGLY 343
R+++ LS +IA + ++L L+++ + + + S T L N + IG
Sbjct: 434 RNIAKLS---GTALIADLFILLGLVYVYVYSIYYIAVNGVASDTMLMFNKADWSLFIGTA 490
Query: 344 GYCYSGHAVFPNIYTSMAKPNQFPAVLVACFGVCTLLYAGGAVMGYKMFGEDTLSQFTLN 403
+ + G + I SM P F L A + +++ ++ Y FG D + LN
Sbjct: 491 IFTFEGIGLLIPIQESMKHPKHFRPSLSAVMCIVAVIFISCGLLCYAAFGSDVKTVVLLN 550
Query: 404 LPQDLVATKIAVWTTVVNPFTKYALTISPVAMSLEE-LIPANHAKSY 449
PQD T + L + P LE P+N + Y
Sbjct: 551 FPQDTSYTLTVQLLYALAILLSTPLQLFPAIRILENWTFPSNASGKY 597
>S361_HUMAN (Q7Z2H8) Proton-coupled amino acid transporter 1
(Proton/amino acid transporter 1) (Solute carrier family
36 member 1)
Length = 476
Score = 64.7 bits (156), Expect = 6e-10
Identities = 96/399 (24%), Positives = 157/399 (39%), Gaps = 46/399 (11%)
Query: 111 QPTEEEKHQRRSSHTLLPPLSRRSSLLKKESKVSHEV--PSRHCSFGQAVLNGINVLCGV 168
Q E + SS + P S L S S++ S ++ Q +++ + G
Sbjct: 4 QRLRNEDYHDYSSTDVSPEESPSEGLNNLSSPGSYQRFGQSNSTTWFQTLIHLLKGNIGT 63
Query: 169 GILSTPYAAKEGGW-LGLSILFIFGILSFYTGLLLRSCLDS----------------EPG 211
G+L P A K G +G L I GI++ + +L C G
Sbjct: 64 GLLGLPLAVKNAGIVMGPISLLIIGIVAVHCMGILVKCAHHFCRRLNKSFVDYGDTVMYG 123
Query: 212 LETYPDIGQAAFGTAGRIAISIVLYVELYGCCIEYIILEGDNLASLFP------NAYLNL 265
LE+ P GR + L V G C Y + DN + N N
Sbjct: 124 LESSPCSWLRNHAHWGRRVVDFFLIVTQLGFCCVYFVFLADNFKQVIEAANGTTNNCHNN 183
Query: 266 GGIELNPQTLFAVVAALAVLP----TVWLRDLSVLSYISAGGVIASVLVVLCLLWIGIED 321
+ L P T+ + + L+ LP V++R+L LS S ++A++ +++ L+ I
Sbjct: 184 ETVILTP-TMDSRLYMLSFLPFLVLLVFIRNLRALSIFS---LLANITMLVSLVMIYQFI 239
Query: 322 VGFQRSGTTLNL----GTLPVAIGLYGYCYSGHAVFPNIYTSMAKPNQFPAVLVACFGVC 377
V + L L T P+ G + + G + + M P +FP +L +
Sbjct: 240 VQRIPDPSHLPLVAPWKTYPLFFGTAIFSFEGIGMVLPLENKMKDPRKFPLILYLGMVIV 299
Query: 378 TLLYAGGAVMGYKMFGEDTLSQFTLNLPQDLVATKIAVWTTVVNPFTKYALTISPVAMSL 437
T+LY +GY FG + TLNLP + + + ++ FT YAL A
Sbjct: 300 TILYISLGCLGYLQFGANIQGSITLNLPNCWLYQSVKLLYSIGIFFT-YALQFYVPA--- 355
Query: 438 EELIP-----ANHAKSYLFSIFIRTGLVFSTLVIGLSVP 471
E +IP A + +F+RT LV T ++ + +P
Sbjct: 356 EIIIPFFVSRAPEHCELVVDLFVRTVLVCLTCILAILIP 394
>S361_MOUSE (Q8K4D3) Proton-coupled amino acid transporter 1
(Proton/amino acid transporter 1) (Solute carrier family
36 member 1)
Length = 475
Score = 63.9 bits (154), Expect = 1e-09
Identities = 83/340 (24%), Positives = 136/340 (39%), Gaps = 42/340 (12%)
Query: 167 GVGILSTPYAAKEGGWL-GLSILFIFGILSFYTGLLLRSCLD------SEP--------- 210
G G+L P A K G L G L + GI++ + +L C ++P
Sbjct: 61 GTGLLGLPLAVKNAGLLLGPLSLLVIGIVAVHCMGILVKCAHHLCRRLNKPFLDYGDTVM 120
Query: 211 -GLETYPDIGQAAFGTAGRIAISIVLYVELYGCCIEYIILEGDNLASLFPNAY-----LN 264
GLE P GR + L V G C Y + DN + A N
Sbjct: 121 YGLECSPSTWVRNHSHWGRRIVDFFLIVTQLGFCCVYFVFLADNFKQVIEAANGTTTNCN 180
Query: 265 LGGIELNPQTLFAVVAALAVLPTV----WLRDLSVLSYISAGGVIASVLVVLCLLWIGIE 320
+ T+ + + L+ LP + ++R+L VLS S ++A++ + + L+ I
Sbjct: 181 NNVTVIPTPTMDSRLYMLSFLPFLVLLSFIRNLRVLSIFS---LLANISMFVSLIMIYQF 237
Query: 321 DVGFQRSGTTLNL----GTLPVAIGLYGYCYSGHAVFPNIYTSMAKPNQFPAVLVACFGV 376
V + L L T P+ G + + G V + M +FP +L +
Sbjct: 238 IVQRIPDPSHLPLVAPWKTYPLFFGTAIFAFEGIGVVLPLENKMKDSQKFPLILYLGMAI 297
Query: 377 CTLLYAGGAVMGYKMFGEDTLSQFTLNLPQDLVATKIAVWTTVVNPFTKYALTISPVAMS 436
T+LY +GY FG + TLNLP + + + ++ FT YAL A
Sbjct: 298 ITVLYISLGSLGYLQFGANIKGSITLNLPNCWLYQSVKLLYSIGIFFT-YALQFYVAA-- 354
Query: 437 LEELIPANHAK-----SYLFSIFIRTGLVFSTLVIGLSVP 471
E +IPA ++ + + +RT +V T V+ + +P
Sbjct: 355 -EIIIPAIVSRVPEHFELMVDLCVRTAMVCVTCVLAILIP 393
>S361_RAT (Q924A5) Proton-coupled amino acid transporter 1
(Proton/amino acid transporter 1) (Solute carrier family
36 member 1) (Lysosomal amino acid transporter 1)
(LYAAT-1) (Neutral amino acid/proton symporter)
Length = 475
Score = 62.4 bits (150), Expect = 3e-09
Identities = 85/341 (24%), Positives = 136/341 (38%), Gaps = 44/341 (12%)
Query: 167 GVGILSTPYAAKEGGWL-GLSILFIFGILSFYTGLLLRSCLD------SEP--------- 210
G G+L P A K G L G L + GI++ + +L C ++P
Sbjct: 61 GTGLLGLPLAVKNAGLLLGPLSLLVIGIVAVHCMGILVKCAHHLCRRLNKPFLDYGDTVM 120
Query: 211 -GLETYPDIGQAAFGTAGRIAISIVLYVELYGCCIEYIILEGDNLASLFPNAY------L 263
GLE P GR + L V G C Y + DN + A
Sbjct: 121 YGLECSPSTWIRNHSHWGRRIVDFFLVVTQLGFCCVYFVFLADNFKQVIEAANGTTTNCN 180
Query: 264 NLGGIELNPQTLFAVVAALAVLPTV----WLRDLSVLSYISAGGVIASVLVVLCLLWIGI 319
N + L P T+ + + L LP + ++R+L +LS S ++A++ + + L+ I
Sbjct: 181 NNETVILTP-TMDSRLYMLTFLPFLVLLSFIRNLRILSIFS---LLANISMFVSLIMIYQ 236
Query: 320 EDVGFQRSGTTLNL----GTLPVAIGLYGYCYSGHAVFPNIYTSMAKPNQFPAVLVACFG 375
V + L L T P+ G + + G V + M +FP +L
Sbjct: 237 FIVQRIPDPSHLPLVAPWKTYPLFFGTAIFAFEGIGVVLPLENKMKDSQKFPLILYLGMA 296
Query: 376 VCTLLYAGGAVMGYKMFGEDTLSQFTLNLPQDLVATKIAVWTTVVNPFTKYALTISPVAM 435
+ T+LY +GY FG D TLNLP + + + ++ FT YAL A
Sbjct: 297 IITVLYISLGSLGYLQFGADIKGSITLNLPNCWLYQSVKLLYSIGIFFT-YALQFYVAA- 354
Query: 436 SLEELIPANHAK-----SYLFSIFIRTGLVFSTLVIGLSVP 471
E +IPA ++ + + RT +V T V+ + +P
Sbjct: 355 --EIIIPAIVSRVPERFELVVDLSARTAMVCVTCVLAVLIP 393
>AVT6_YEAST (P40074) Vacuolar amino acid transporter 6
Length = 448
Score = 57.8 bits (138), Expect = 7e-08
Identities = 73/318 (22%), Positives = 133/318 (40%), Gaps = 49/318 (15%)
Query: 153 SFGQAVLNGINVLCGVGILSTPYAAKEGGWLGLSILFIFGILSFYTGLLLRSCLDSEPGL 212
S VL ++ CG GIL+ PYA K G + I+ + G L + +
Sbjct: 4 SIRSGVLTLLHTACGAGILAMPYAFKPFGLIPGVIMIVL------CGACAMQSLFIQARV 57
Query: 213 ETYPDIGQAAFGTAGR-------IAISIVLYVELYGCCIEYIILEGDNLASLFP----NA 261
Y G+A+F R I + + ++ +G + Y+I+ GD + + NA
Sbjct: 58 AKYVPQGRASFSALTRLINPNLGIVFDLAIAIKCFGVGVSYMIVVGDLMPQIMSVWTRNA 117
Query: 262 YLNLGGIELNPQTLFAVVAALAVLPTVWLRDLSVLSYISAGGV--IASVLVVLCLLWIGI 319
+L LN +++ V P +L+ L+ L Y S + +A + V++ L ++
Sbjct: 118 WL------LNRNVQISLIMLFFVAPLSFLKKLNSLRYASMVAISSVAYLCVLVLLHYVAP 171
Query: 320 EDVGFQRSGT----------TLN-LGTLPVAIGLYGYCYSGHAVFPNIYTSMAKPNQFPA 368
D + G LN L TLP+ + Y C+ H +F I + + ++F
Sbjct: 172 SDEILRLKGRISYLLPPQSHDLNVLNTLPIFVFAY-TCH--HNMFSII--NEQRSSRFEH 226
Query: 369 VL---VACFGVCTLLYAGGAVMGYKMFGEDTLSQFTLNLPQDLVAT--KIAVWTTVVNPF 423
V+ + + +LY GY FG++ + + PQ + +T +IA+ V+ F
Sbjct: 227 VMKIPLIAISLALILYIAIGCAGYLTFGDNIIGNIIMLYPQAVSSTIGRIAIVLLVMLAF 286
Query: 424 TKYALTISPVAMSLEELI 441
L P S+ +++
Sbjct: 287 ---PLQCHPARASIHQIL 301
>YMJ2_CAEEL (P34479) Hypothetical protein F59B2.2 in chromosome III
Length = 460
Score = 57.4 bits (137), Expect = 1e-07
Identities = 61/282 (21%), Positives = 107/282 (37%), Gaps = 24/282 (8%)
Query: 156 QAVLNGINVLCGVGILSTPYAAKEGG-WLGLSILFIFGILSFYTGLLL------------ 202
+AVL + G S PYA K GG W+ + F+ L++Y +L
Sbjct: 41 RAVLTLSKSMFNAGCFSLPYAWKLGGLWVSFVMSFVIAGLNWYGNHILVRASQHLAKKSD 100
Query: 203 RSCLDSEPGLETYPDIGQAAF----GTAGRIAISIVLYVELYGCCIEYIILEGDNLASLF 258
RS LD + D F A +++ + G C I+ DNL +L
Sbjct: 101 RSALDYGHFAKKVCDYSDIRFLRNNSKAVMYFVNVTILFYQLGMCSVAILFISDNLVNLV 160
Query: 259 PNAYLNLGGIELNPQTLFAVVAALAVLPTVWLRDLSVLSYISAGGVIASVLVVLCLLWIG 318
+ +LGG L A V+ +L T ++ ++S+ + + V+ ++
Sbjct: 161 GD---HLGGTRHQQMILMATVSLFFILLTNMFTEMRIVSFFALVSSVFFVIGAAVIMQYT 217
Query: 319 IEDVG-FQRSGTTLNLGTLPVAIGLYGYCYSGHAVFPNIYTSMAKPNQFPA---VLVACF 374
++ + + N IG+ Y + G + I + P F A VL
Sbjct: 218 VQQPNQWDKLPAATNFTGTITMIGMSMYAFEGQTMILPIENKLDNPAAFLAPFGVLSTTM 277
Query: 375 GVCTLLYAGGAVMGYKMFGEDTLSQFTLNLPQDLVATKIAVW 416
+CT GY FG+ T N+P++ + + + V+
Sbjct: 278 IICTAFMTALGFFGYTGFGDSIAPTITTNVPKEGLYSTVNVF 319
>AVT2_YEAST (P39981) Vacuolar amino acid transporter 2
Length = 480
Score = 53.1 bits (126), Expect = 2e-06
Identities = 78/341 (22%), Positives = 136/341 (39%), Gaps = 29/341 (8%)
Query: 153 SFGQAVLNGINVLCGVGILSTPYAAKEGGWLGLSILFI-FGILSFYTGLLLRSCLDSEPG 211
S A +N N + G GI++ P+A K G LG + ++ G + +T L+ L + G
Sbjct: 68 SMRMAFMNLANSILGAGIITQPFAIKNAGILGGLLSYVALGFIVDWTLRLIVINL-TLAG 126
Query: 212 LETYPDIGQAAFGTAGRIAISIVLYVELYGCCIEYIILEGDNLASLFPNAY-LNLGGIE- 269
TY + G G++ I + +G CI Y I+ GD + + + N G +
Sbjct: 127 KRTYQGTVEHVMGKKGKLLILFTNGLFAFGGCIGYCIIIGDTIPHVLRAIFSQNDGNVHF 186
Query: 270 -LNPQTLFAVVAALAVLPTVWLRDLSVLSYISAGGVIASVLVVLCLLWIGIEDVGFQRSG 328
L + +V P R++ LS S VI+ +++VL ++ G + + G
Sbjct: 187 WLRRNVIIVMVTTFISFPLSMKRNIEALSKASFLAVISMIIIVLTVVIRG-PMLPYDWKG 245
Query: 329 TTLNL------GTLPVAIGLYGYCYSGHAVFPNIYTSM-----AKPNQFPAVLVACFGVC 377
+L L T+ ++ + + H I+ SM AK + + + +C
Sbjct: 246 HSLKLSDFFMKATIFRSLSVISFALVCHHNTSFIFFSMRNRSVAKFTRLTHISIIISVIC 305
Query: 378 TLLYAGGAVMGYKMFGEDTLSQFTLNLPQDLVATKIAVWTTVVNPFTKYALTISPVAMSL 437
L G+ +F E T + P A IA N T + + I + +
Sbjct: 306 CALM---GYSGFAVFKEKTKGNVLNSFPGTDTAINIARLCFGFNMLTTFPMEIFVLRDVV 362
Query: 438 EELI-PANHAKSY--------LFSIFIRTGLVFSTLVIGLS 469
L+ N K+Y + I + LVF T+ I L+
Sbjct: 363 GNLLHECNLIKNYDEHTQLSGKQHVVITSSLVFITMGISLT 403
>AVT5_YEAST (P38176) Vacuolar amino acid transporter 5
Length = 509
Score = 50.1 bits (118), Expect = 2e-05
Identities = 81/348 (23%), Positives = 152/348 (43%), Gaps = 54/348 (15%)
Query: 130 LSRRSSLLKKESKVSH--EVPSRHCSFGQAVLNGINVLCGVGILSTPYAAKEGGWL-GLS 186
++R +S +K + KVS +PS S VL ++ CG G+L+ P+A K G + GL
Sbjct: 32 VARTNSKIKWKRKVSSFLNMPSNVRS---GVLTLLHTACGAGVLAMPFAFKPFGLMPGLI 88
Query: 187 ILFIFGILSFYTGLLLRSCLDSEPGLETYPDIGQAAFGTAGRI---AISIV----LYVEL 239
L GI S GLLL++ + + P A+F ++ +IS+V + V+
Sbjct: 89 TLTFCGICSL-CGLLLQTRI-----AKYVPKSENASFAKLTQLINPSISVVFDFAIAVKC 142
Query: 240 YGCCIEYIILEGDNLASLFPNAYL----NLGGIE-----LNPQTLFAVVAALAVLPTVWL 290
+G + Y+I+ GD + + + + N+ G + L+ + ++ + P +
Sbjct: 143 FGVGVSYLIIVGDLVPQIVQSIFYRNDDNMSGSQEHHMFLDRRLYITLIIVFVISPLCFK 202
Query: 291 RDLSVLSYISAGGVIASVLVVLCLLWIGIEDVGFQR-----------SGTTLNLGTLPVA 339
R L+ L Y S +++ + +++ + +R S + L TLP+
Sbjct: 203 RSLNSLRYASMIAIVSVAYLSGLIIYHFVNRHQLERGQVYFMVPHGDSQSHSPLTTLPIF 262
Query: 340 IGLYGYCYSGHAVFPNIYTSMAKP----NQFP--AVLVACFGVCTLLYAGGAVMGYKMFG 393
+ Y C+ H +F I + K + P A+++A F + GG GY FG
Sbjct: 263 VFAY-TCH--HNMFSVINEQVDKSFKVIRRIPIFAIVLAYF---LYIIIGGT--GYMTFG 314
Query: 394 EDTLSQFTLNLPQDLVATKIAVWTTVVNPFTKYALTISPVAMSLEELI 441
E+ + L L + ++T I ++ + L P S++ +I
Sbjct: 315 ENIVGNI-LTLYPNSISTTIGRLAMLLLVMLAFPLQCHPCRSSVKNII 361
>AVT7_YEAST (P40501) Vacuolar amino acid transporter 7
Length = 490
Score = 43.9 bits (102), Expect = 0.001
Identities = 63/303 (20%), Positives = 120/303 (38%), Gaps = 39/303 (12%)
Query: 160 NGINVLCGVGILSTPYAAKEGGWLGLSILFIFGILSFYTGL-LLRSCLDS--EPGLETYP 216
N + + G G L+ PY+ K G L IL + ++ GL +L C + P ++
Sbjct: 13 NLVKTIVGAGTLAIPYSFKSDGVLVGVILTLLAAVTSGLGLFVLSKCSKTLINPRNSSFF 72
Query: 217 DIGQAAFGTAGRIAISIVLYVELYGCCIEYIILEGDNLASLFPNAYLNLGGIELNPQTLF 276
+ + T I + + V+ +G + Y++L GD LFP + GG + +
Sbjct: 73 TLCMLTYPTLAPI-FDLAMIVQCFGVGLSYLVLIGD----LFPGLF---GG----ERNYW 120
Query: 277 AVVAALAVLPTVWLRDLSVLSYISAGGVIASVLVVLCLLWIGIEDVGFQRSGTTLN---- 332
+ +A+ ++P ++ L L Y S G+ A + + + + ++G L
Sbjct: 121 IIASAVIIIPLCLVKKLDQLKYSSILGLFALAYISILVFSHFVFELGKGELTNILRNDIC 180
Query: 333 ----------LGTLPVAIGLYGYCYSGHA-VFPNIYTSMAKPN---QFPAVLVACFGVCT 378
L T + I + ++G +FP I + K N V+ + T
Sbjct: 181 WWKIHDFKGLLSTFSIII----FAFTGSMNLFPMI--NELKDNSMENITFVINNSISLST 234
Query: 379 LLYAGGAVMGYKMFGEDTLSQFTLNLPQDLVATKIAVWTTVVNPFTKYALTISPVAMSLE 438
L+ + GY FG +TL LN + + I + + L P+ +++
Sbjct: 235 ALFLIVGLSGYLTFGNETLGNLMLNYDPNSIWIVIGKFCLGSMLILSFPLLFHPLRIAVN 294
Query: 439 ELI 441
+I
Sbjct: 295 NVI 297
Database: sprot
Posted date: Nov 25, 2004 10:54 AM
Number of letters in database: 59,974,054
Number of sequences in database: 164,201
Lambda K H
0.322 0.138 0.422
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 67,919,765
Number of Sequences: 164201
Number of extensions: 2984313
Number of successful extensions: 10437
Number of sequences better than 10.0: 83
Number of HSP's better than 10.0 without gapping: 21
Number of HSP's successfully gapped in prelim test: 64
Number of HSP's that attempted gapping in prelim test: 10129
Number of HSP's gapped (non-prelim): 214
length of query: 552
length of database: 59,974,054
effective HSP length: 115
effective length of query: 437
effective length of database: 41,090,939
effective search space: 17956740343
effective search space used: 17956740343
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 68 (30.8 bits)
Medicago: description of AC144720.2