BLAST2 result
BLASTP 2.2.2 [Dec-14-2001]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= AC144617.9 + phase: 0
(1424 letters)
Database: sprot
164,201 sequences; 59,974,054 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
PDRF_YEAST (Q04182) ATP-dependent permease PDR15 452 e-126
CGR1_CANGA (O74208) ATP-binding cassette transporter CGR1 (Pleom... 450 e-125
PDR5_YEAST (P33302) Suppressor of toxicity of sporidesmin 445 e-124
YN99_YEAST (P53756) Probable ATP-dependent transporter YNR070W 435 e-121
CDR2_CANAL (P78595) Multidrug resistance protein CDR2 434 e-121
BFR1_SCHPO (P41820) Brefeldin A resistance protein 431 e-120
CDR1_CANAL (P43071) Multidrug resistance protein CDR1 426 e-118
PDRA_YEAST (P51533) ATP-dependent permease PDR10 420 e-116
CDR4_CANAL (O74676) ABC transporter CDR4 420 e-116
SNQ2_YEAST (P32568) SNQ2 protein 406 e-112
CDR3_CANAL (O42690) Opaque-specific ABC transporter CDR3 404 e-112
PDRC_YEAST (Q02785) ATP-dependent permease PDR12 402 e-111
AUS1_YEAST (Q08409) ATP-dependent permease AUS1 309 4e-83
PDRB_YEAST (P40550) ATP-dependent permease PDR11 301 1e-80
ABG1_HUMAN (P45844) ATP-binding cassette, sub-family G, member 1... 224 2e-57
ABG4_HUMAN (Q9H172) ATP-binding cassette, sub-family G, member 4 216 4e-55
WHIT_DROME (P10090) White protein 206 4e-52
WHIT_CERCA (Q17320) White protein 206 4e-52
WHIT_ANOGA (Q27256) White protein 202 5e-51
YQ5C_CAEEL (Q09466) Putative ABC transporter C16C10.12 in chromo... 201 9e-51
>PDRF_YEAST (Q04182) ATP-dependent permease PDR15
Length = 1529
Score = 452 bits (1162), Expect = e-126
Identities = 359/1312 (27%), Positives = 596/1312 (45%), Gaps = 135/1312 (10%)
Query: 131 FVNVIEGCLNNLQIIPSPKKQ---LHILQNVSGILKPRRMTLLLGPPGSGKTTLLLALAG 187
F N++ L + P K+ IL+ + G L P + ++LG PGSG TTLL +++
Sbjct: 159 FANIVPKLLTKGLRLLKPSKEEDTFQILKPMDGCLNPGELLVVLGRPGSGCTTLLKSISS 218
Query: 188 IL-GKDLKQSGRVTYNGKGLEEFVPQRTS--AYVSQYDNHIGEMTVRETLAFSARCQGVG 244
G + + V+YNG + Y ++ D H+ +TV +TL AR
Sbjct: 219 NSHGFKIAKDSIVSYNGLSSSDIRKHYRGEVVYNAESDIHLPHLTVYQTLFTVARM---- 274
Query: 245 QNYEMLTELLRKEKESKIEPDPDINAYMKEAAIEGHQNSVVIDYILKILGLDVCADTMVG 304
K +++I+ D AY V + + GL DT VG
Sbjct: 275 -----------KTPQNRIK-GVDREAYANH----------VTEVAMATYGLSHTRDTKVG 312
Query: 305 DQMIRGISGGEKKRLTTGEMLVGPIKVLFMDEISNGLDSSTTFQIINSIKQSIHILNGTA 364
+ ++RG+SGGE+KR++ E+ + + D + GLDS+T + I ++K I A
Sbjct: 313 NDLVRGVSGGERKRVSIAEVAICGARFQCWDNATRGLDSATALEFIRALKTQADIGKTAA 372
Query: 365 LVSLLQPAPETYELFDDIILLTDGQIVYQGPREYVLEFFESTGFKCPERKGVADFLQEVT 424
V++ Q + + Y+LFD + +L DG +Y GP + ++F+ G+ CP R+ ADFL +T
Sbjct: 373 TVAIYQCSQDAYDLFDKVCVLDDGYQLYFGPAKDAKKYFQDMGYYCPPRQTTADFLTSIT 432
Query: 425 S--------------------RKDQWQYWAREDEPYNFVTVKDFARAFELFHIGKQLGEE 464
S KD +YW + + N +KD E
Sbjct: 433 SPTERIISKEFIEKGTRVPQTPKDMAEYWLQSESYKNL--IKDIDSTLEK---NTDEARN 487
Query: 465 LADPFDKSKFHSNVLITKKYGINKKELLRACASRELLLMKRNSFVYIFKATQLTYLATLT 524
+ +K + Y +N ++ R MK+++ V +++ + +A +
Sbjct: 488 IIRDAHHAKQAKRAPPSSPYVVNYGMQVKYLLIRNFWRMKQSASVTLWQVIGNSVMAFIL 547
Query: 525 TTLFLRTKMYHSTIEDAQTYM---GALFFTVTVAMFNGISELNMTIMKLPIFYKQRDLLF 581
++F + + D T+ A+FF + F+ + E+ PI K R
Sbjct: 548 GSMFYKVMKKN----DTSTFYFRGAAMFFAILFNAFSCLLEIFSLYETRPITEKHRTYSL 603
Query: 582 YPSWAYSLPPWILKIPITIIEVAIWECISYYAIGFDPNIGRFFKQSLVVLCINQMASALF 641
Y A + + ++P +I + I Y+ + F N G FF L+ + S LF
Sbjct: 604 YHPSADAFASVLSEMPPKLITAVCFNIIFYFLVDFRRNGGVFFFYFLINVIATFTLSHLF 663
Query: 642 RFMAALGRDIVVANTFGTFSLLAVTVLGGFVISREDVHKWFLWGYWSSPLMYGQNAIAVN 701
R + +L + + A + LLA+++ GF I + + W +W ++ +PL Y ++ +N
Sbjct: 664 RCVGSLTKTLQEAMVPASMLLLAISMYTGFAIPKTKILGWSIWIWYINPLAYLFESLMIN 723
Query: 702 EF------------LGHGWRKVA------------PNSNETLGVSILKSRGFFPQAYWYW 737
EF G ++ + P ++ LG LK + + W
Sbjct: 724 EFHDRRFPCAQYIPAGPAYQNITGTQRVCSAVGAYPGNDYVLGDDFLKESYDYEHKH-KW 782
Query: 738 IGVGALIGYVFLFNFLFALALHF----------LSPFRKDQAGLSQE-KLQERNASTD-E 785
G G + YV F F++ + + + R L +E KLQE++ D E
Sbjct: 783 RGFGIGMAYVVFFFFVYLILCEYNEGAKQKGEMVVFLRSKIKQLKKEGKLQEKHRPGDIE 842
Query: 786 EFIQSQQQENSSNTKMDEEVSENKASSSGRKGMVLPFQPLSLTFDDITYSVDMPQGMKNQ 845
S ++ K+ ++ SE SSS G+ L + D+ Y V + G +
Sbjct: 843 NNAGSSPDSATTEKKILDDSSEGSDSSSDNAGLGLSKSEAIFHWRDLCYDVPIKGGQR-- 900
Query: 846 GVTEDRLELLKGVSGAFRPGVLTALMGVSGAGKTTLMDVLAGIKTSGYIEGNIKVSGYQK 905
+L V G +PG LTALMG SGAGKTTL+D LA T G I GNI V G +
Sbjct: 901 -------RILNNVDGWVKPGTLTALMGASGAGKTTLLDCLAERVTMGVITGNIFVDGRLR 953
Query: 906 NQKSFARISGYCEQFDIHSPNVTVYESLLYSAWLRLSPEVDHATRKMFIEEVMELVELNS 965
++ SF R GYC+Q D+H TV ESL +SA+LR V + ++EEV++++E+
Sbjct: 954 DE-SFPRSIGYCQQQDLHLKTATVRESLRFSAYLRQPSSVSIEEKNRYVEEVIKILEMQQ 1012
Query: 966 LREALVGLPGENGLSTEQRKRLTIAVELVANPS-IIFMDEPTSGLDARAAAIVMRTVRNT 1024
+A+VG+ GE GL+ EQRKRLTI VEL A P ++F+DEPTSGLD++ A + +R
Sbjct: 1013 YSDAVVGVAGE-GLNVEQRKRLTIGVELAARPKLLVFLDEPTSGLDSQTAWDTCQLMRKL 1071
Query: 1025 VDTGRTVVCTIHQPSIDIFDSFDELLLLKLGGEQIYAGPIGNQCSDLIQYFEAIQGVPTI 1084
G+ ++CTIHQPS + FD LL L+ GG+ +Y G +G C +I YFE+ +G
Sbjct: 1072 ATHGQAILCTIHQPSAILMQQFDRLLFLQKGGQTVYFGDLGEGCKTMIDYFES-KGAHKC 1130
Query: 1085 KDGYNPATWMLEITSAGKEANLKVNFTDVYKNSELHRRNKQLI--QELSVPSQSSKDLHF 1142
NPA WMLE+ A ++ ++ +V++NS+ ++ ++ + E ++P +S +
Sbjct: 1131 PPDANPAEWMLEVVGAAPGSHATQDYNEVWRNSDEYKAVQEELDWMEKNLPGRSKEP--- 1187
Query: 1143 DAQYSQTFLAQCTY----CLWKQHLSYWRNTSYTAVRLLFTIMTGILFGLIFWGVGAKSK 1198
A+ + F A Y + YWR+ Y + + TI + G F+ +
Sbjct: 1188 TAEEHKPFAASLYYQFKMVTIRLFQQYWRSPDYLWSKFILTIFNQVFIGFTFF---KADR 1244
Query: 1199 KEQDLFNAMGSMYAAVTFIGVVNGASVQPIVAIERTVFYRERAAGMYSAMPYALAQVIIE 1258
Q L N M S++ + + V RER + +S + + L+Q+I+E
Sbjct: 1245 SLQGLQNQMLSIFMYTVIFNPILQQYLPSFVQQRDLYEARERPSRTFSWLAFFLSQIIVE 1304
Query: 1259 LP-HILVQAVVYGIIVYAMMGFEWTASKV----LWNLFFTYFSFLYYTYYGMMTMAITPN 1313
+P +IL + Y I YA +GF AS F FS +Y Y G M + +
Sbjct: 1305 IPWNILAGTIAYCIYYYA-VGFYANASAAGQLHERGALFWLFSIAFYVYIGSMGLLMISF 1363
Query: 1314 PHV---AGILSTSFYAIWCLFSGFIIPLSRIPIWWKWYYWICPVAWTLNGLV 1362
V A + T + + F G + +P +W + Y + P+ + ++ L+
Sbjct: 1364 NEVAETAAHMGTLLFTMALSFCGVMATPKVMPRFWIFMYRVSPLTYMIDALL 1415
Score = 114 bits (285), Expect = 2e-24
Identities = 127/564 (22%), Positives = 233/564 (40%), Gaps = 64/564 (11%)
Query: 849 EDRLELLKGVSGAFRPGVLTALMGVSGAGKTTLMDVLAGIKTSGYI--EGNIKVSGYQKN 906
ED ++LK + G PG L ++G G+G TTL+ ++ I + + +G +
Sbjct: 180 EDTFQILKPMDGCLNPGELLVVLGRPGSGCTTLLKSISSNSHGFKIAKDSIVSYNGLSSS 239
Query: 907 --QKSFARISGYCEQFDIHSPNVTVYESLLYSAWLRLSPE----VDHATRKMFIEEV-ME 959
+K + Y + DIH P++TVY++L A ++ VD + EV M
Sbjct: 240 DIRKHYRGEVVYNAESDIHLPHLTVYQTLFTVARMKTPQNRIKGVDREAYANHVTEVAMA 299
Query: 960 LVELNSLREALVGLPGENGLSTEQRKRLTIAVELVANPSIIFMDEPTSGLDARAAAIVMR 1019
L+ R+ VG G+S +RKR++IA + D T GLD+ A +R
Sbjct: 300 TYGLSHTRDTKVGNDLVRGVSGGERKRVSIAEVAICGARFQCWDNATRGLDSATALEFIR 359
Query: 1020 TVRNTVDTGRTVVCT-IHQPSIDIFDSFDELLLLKLGGEQIYAGPIGNQCSDLIQYFEAI 1078
++ D G+T I+Q S D +D FD++ +L G Q+Y GP D +YF+ +
Sbjct: 360 ALKTQADIGKTAATVAIYQCSQDAYDLFDKVCVLD-DGYQLYFGP----AKDAKKYFQDM 414
Query: 1079 QGVPTIKDGY------NPATWMLEITSAGK--------EANLKV-----NFTDVYKNSEL 1119
GY A ++ ITS + E +V + + + SE
Sbjct: 415 --------GYYCPPRQTTADFLTSITSPTERIISKEFIEKGTRVPQTPKDMAEYWLQSES 466
Query: 1120 HRRNKQLIQELSVPSQSS--------KDLHFDAQ---------YSQTFLAQCTYCLWKQH 1162
+ K LI+++ + + +D H Q Y + Q Y L +
Sbjct: 467 Y---KNLIKDIDSTLEKNTDEARNIIRDAHHAKQAKRAPPSSPYVVNYGMQVKYLLIRNF 523
Query: 1163 LSYWRNTSYTAVRLLFTIMTGILFGLIFWGVGAKSKKEQDLFNAMGSMYAAVTFIGVVNG 1222
++ S T +++ + + G +F+ V K+ F +M+ A+ F
Sbjct: 524 WRMKQSASVTLWQVIGNSVMAFILGSMFYKVMKKNDTSTFYFRG-AAMFFAILFNAFSCL 582
Query: 1223 ASVQPIVAIERTVFYRERAAGMYSAMPYALAQVIIELPHILVQAVVYGIIVYAMMGFEWT 1282
+ + R + + R +Y A A V+ E+P L+ AV + II Y ++ F
Sbjct: 583 LEIFSLYET-RPITEKHRTYSLYHPSADAFASVLSEMPPKLITAVCFNIIFYFLVDFRRN 641
Query: 1283 ASKVLWNLFFTYFSFLYYTYYGMMTMAITPNPHVAGILSTSFYAIWCLFSGFIIPLSRIP 1342
+ + ++ ++T A + ++ +++GF IP ++I
Sbjct: 642 GGVFFFYFLINVIATFTLSHLFRCVGSLTKTLQEAMVPASMLLLAISMYTGFAIPKTKIL 701
Query: 1343 IWWKWYYWICPVAWTLNGLVTSQY 1366
W W ++I P+A+ L+ +++
Sbjct: 702 GWSIWIWYINPLAYLFESLMINEF 725
>CGR1_CANGA (O74208) ATP-binding cassette transporter CGR1
(Pleomorphic drug resistance homolog)
Length = 1542
Score = 450 bits (1157), Expect = e-125
Identities = 355/1324 (26%), Positives = 612/1324 (45%), Gaps = 143/1324 (10%)
Query: 131 FVNVIEGCLNNLQIIPSPKKQ---LHILQNVSGILKPRRMTLLLGPPGSGKTTLLLALAG 187
F+N+ LN + P ++ IL+ + G+LKP + ++LG PGSG TTLL +++
Sbjct: 148 FLNLPVKLLNAVWRKARPARESDTFRILKPMDGLLKPGELLVVLGRPGSGCTTLLKSISS 207
Query: 188 IL-GKDLKQSGRVTYNGKGLEEFVPQRTS--AYVSQYDNHIGEMTVRETLAFSARCQGVG 244
G + + ++YNG E Y ++ D H+ +TV +TL AR
Sbjct: 208 TTHGFQISKDSVISYNGLTPNEIKKHYRGEVVYNAEADIHLPHLTVYQTLVTVARL---- 263
Query: 245 QNYEMLTELLRKEKESKIEPDPDINAYMKEAAIEGHQNSVVIDYILKILGLDVCADTMVG 304
K ++++ K E N V D + GL DT VG
Sbjct: 264 -----------KTPQNRV----------KGVTREDFANHVT-DVAMATYGLSHTRDTKVG 301
Query: 305 DQMIRGISGGEKKRLTTGEMLVGPIKVLFMDEISNGLDSSTTFQIINSIKQSIHILNGTA 364
+ ++RG+SGGE+KR++ E+ + K D + GLDS+T + + ++K HI A
Sbjct: 302 NDLVRGVSGGERKRVSIAEVWICGSKFQCWDNATRGLDSATALEFVRALKTQAHIAKNVA 361
Query: 365 LVSLLQPAPETYELFDDIILLTDGQIVYQGPREYVLEFFESTGFKCPERKGVADFLQEVT 424
V++ Q + + Y LF+ + +L +G +Y G ++ +F+ G+ CP+R+ + DFL +T
Sbjct: 362 TVAIYQCSQDAYNLFNKVSVLYEGYQIYFGDAQHAKVYFQKMGYFCPKRQTIPDFLTSIT 421
Query: 425 SRKDQWQYWAREDEPYNFVTVK------DFARAFELFHIGKQLGEELADPF------DK- 471
S ++ R ++ Y +K D + KQL EE+ + DK
Sbjct: 422 SPAER-----RINKEYLDKGIKVPQTPLDMVEYWHNSEEYKQLREEIDETLAHQSEDDKE 476
Query: 472 -------SKFHSNVLITKKYGINKKELLRACASRELLLMKRNSFVYIFKATQLTYLATLT 524
+K + Y ++ ++ R +K ++ V +F+ + +A +
Sbjct: 477 EIKEAHIAKQSKRARPSSPYVVSYMMQVKYILIRNFWRIKNSASVTLFQVFGNSAMAFIL 536
Query: 525 TTLFLRTKMYHSTIEDAQTYMG-ALFFTVTVAMFNGISELNMTIMKLPIFYKQRDLLFYP 583
++F K+ + D + G A+FF + F+ + E+ PI K R Y
Sbjct: 537 GSMFY--KIQKGSSADTFYFRGAAMFFAILFNAFSSLLEIFSLYEARPITEKHRTYSLYH 594
Query: 584 SWAYSLPPWILKIPITIIEVAIWECISYYAIGFDPNIGRFFKQSLVVLCINQMASALFRF 643
A + I +IP I+ ++ I Y+ + F + GRFF L+ + S LFR
Sbjct: 595 PSADAFASVISEIPPKIVTAILFNIIFYFLVNFRRDAGRFFFYFLINVIAVFAMSHLFRC 654
Query: 644 MAALGRDIVVANTFGTFSLLAVTVLGGFVISREDVHKWFLWGYWSSPLMYGQNAIAVNEF 703
+ +L + + A + LLA+++ GF I R + W W ++ +PL Y ++ VNEF
Sbjct: 655 VGSLTKTLQEAMVPASMLLLALSMYTGFAIPRTKMLGWSKWIWYINPLAYLFESLMVNEF 714
Query: 704 LGH------------------GWRKVAPNSNETLGVSILKSRGFFPQAYWY-----WIGV 740
G +V + G + F ++Y Y W G
Sbjct: 715 HDRRFPCNTYIPRGGAYNDVTGTERVCASVGARPGNDYVLGDDFLKESYDYENKHKWRGF 774
Query: 741 GALIGYVFLFNFLFALALHF-----------LSPFRKDQAGLSQEKLQER-NASTDEEFI 788
G + YV F F++ + F + P + + K++++ TD+ I
Sbjct: 775 GVGMAYVIFFFFVYLILCEFNEGAKQKGEMLVFPHSVVKRMKKEGKIRDKTKMHTDKNDI 834
Query: 789 QSQQQENSSNTKMD--------EEVSENKASSSGRKG----MVLPFQPLSLTFDDITYSV 836
++ + +SN + +E +++++ +SG +G + L + ++ Y V
Sbjct: 835 ENNSESITSNATNEKNMLQDTYDENADSESITSGSRGGSPQVGLSKSEAIFHWQNLCYDV 894
Query: 837 DMPQGMKNQGVTEDRLELLKGVSGAFRPGVLTALMGVSGAGKTTLMDVLAGIKTSGYIEG 896
+ TE R +L V G +PG LTALMG SGAGKTTL+D LA T G I G
Sbjct: 895 PIK--------TEVR-RILNNVDGWVKPGTLTALMGASGAGKTTLLDCLAERTTMGVITG 945
Query: 897 NIKVSGYQKNQKSFARISGYCEQFDIHSPNVTVYESLLYSAWLRLSPEVDHATRKMFIEE 956
++ V+G + SF+R GYC+Q D+H TV ESL +SA+LR V + ++E
Sbjct: 946 DVMVNG-RPRDTSFSRSIGYCQQQDLHLKTATVRESLRFSAYLRQPSSVSIEEKNEYVEA 1004
Query: 957 VMELVELNSLREALVGLPGENGLSTEQRKRLTIAVELVANPS-IIFMDEPTSGLDARAAA 1015
V++++E+ + +A+VG+PGE GL+ EQRKRLTI VEL A P ++F+DEPTSGLD++ A
Sbjct: 1005 VIKILEMETYADAVVGVPGE-GLNVEQRKRLTIGVELAAKPKLLVFLDEPTSGLDSQTAW 1063
Query: 1016 IVMRTVRNTVDTGRTVVCTIHQPSIDIFDSFDELLLLKLGGEQIYAGPIGNQCSDLIQYF 1075
+ ++ + G+ ++CTIHQPS + FD LL L+ GG+ +Y G +G C +I+YF
Sbjct: 1064 ATCQLMKKLANHGQAILCTIHQPSAMLMQEFDRLLFLQKGGQTVYFGDLGKGCKTMIKYF 1123
Query: 1076 EAIQGVPTIKDGYNPATWMLEITSAGKEANLKVNFTDVYKNSELHRRNKQLIQELSVPSQ 1135
E G NPA WMLE+ A ++ ++ +V++NSE ++ KQ ++++
Sbjct: 1124 ED-HGAHKCPPDANPAEWMLEVVGAAPGSHANQDYHEVWRNSEQFKQVKQELEQME-KEL 1181
Query: 1136 SSKDLHFDAQYSQTFLAQCTY-----CLWKQHLSYWRNTSYTAVRLLFTIMTGILFGLIF 1190
S K+L D ++ F Y C+ + YWR Y + + TI + G F
Sbjct: 1182 SQKELDNDEDANKEFATSLWYQFQLVCV-RLFQQYWRTPDYLWSKYILTIFNQLFIGFTF 1240
Query: 1191 WGVGAKSKKEQDLFNAMGSMYAAVTFIGVVNGASVQ--PIVAIERTVF-YRERAAGMYSA 1247
+ K + L M + + + N Q P +R ++ RER + +S
Sbjct: 1241 F------KADHTLQGLQNQMLSIFMYTVIFNPLLQQYLPTFVQQRDLYEARERPSRTFSW 1294
Query: 1248 MPYALAQVIIELPHILVQAVVYGIIVYAMMGFEWTASKVLW----NLFFTYFSFLYYTY- 1302
+ LAQ+++E+P +V + I Y +GF AS+ F FS +Y Y
Sbjct: 1295 KAFILAQIVVEVPWNIVAGTLAYCIYYYSVGFYANASQAHQLHERGALFWLFSIAFYVYV 1354
Query: 1303 --YGMMTMAITPNPHVAGILSTSFYAIWCLFSGFIIPLSRIPIWWKWYYWICPVAWTLNG 1360
G+ ++ A + + + + F G + +P +W + Y + P+ + ++
Sbjct: 1355 GSLGLFVISFNEVAETAAHIGSLMFTMALSFCGVMATPDAMPRFWIFMYRVSPLTYLIDA 1414
Query: 1361 LVTS 1364
L+++
Sbjct: 1415 LLST 1418
Score = 120 bits (300), Expect = 3e-26
Identities = 132/560 (23%), Positives = 240/560 (42%), Gaps = 58/560 (10%)
Query: 850 DRLELLKGVSGAFRPGVLTALMGVSGAGKTTLMDVLAGIKTSGYIEGN--IKVSGYQKNQ 907
D +LK + G +PG L ++G G+G TTL+ ++ I + I +G N+
Sbjct: 170 DTFRILKPMDGLLKPGELLVVLGRPGSGCTTLLKSISSTTHGFQISKDSVISYNGLTPNE 229
Query: 908 --KSFARISGYCEQFDIHSPNVTVYESLLYSAWLRLSPE-VDHATRKMFIEEVMELVE-- 962
K + Y + DIH P++TVY++L+ A L+ V TR+ F V ++
Sbjct: 230 IKKHYRGEVVYNAEADIHLPHLTVYQTLVTVARLKTPQNRVKGVTREDFANHVTDVAMAT 289
Query: 963 --LNSLREALVGLPGENGLSTEQRKRLTIAVELVANPSIIFMDEPTSGLDARAAAIVMRT 1020
L+ R+ VG G+S +RKR++IA + D T GLD+ A +R
Sbjct: 290 YGLSHTRDTKVGNDLVRGVSGGERKRVSIAEVWICGSKFQCWDNATRGLDSATALEFVRA 349
Query: 1021 VRNTVDTGRTVVCT-IHQPSIDIFDSFDELLLLKLGGEQIYAGPIGNQCSDLIQYFEAIQ 1079
++ + V I+Q S D ++ F+++ +L G QIY G YF+ +
Sbjct: 350 LKTQAHIAKNVATVAIYQCSQDAYNLFNKVSVL-YEGYQIYFG----DAQHAKVYFQKMG 404
Query: 1080 GV----PTIKDGYNPATWMLE--ITSAGKEANLKV-----NFTDVYKNSELHRR------ 1122
TI D T E I + +KV + + + NSE +++
Sbjct: 405 YFCPKRQTIPDFLTSITSPAERRINKEYLDKGIKVPQTPLDMVEYWHNSEEYKQLREEID 464
Query: 1123 ---------NKQLIQELSVPSQSSKDLHFDAQYSQTFLAQCTYCLWKQHLSYWRNTSYTA 1173
+K+ I+E + QS K + Y +++ Q Y L + + S T
Sbjct: 465 ETLAHQSEDDKEEIKEAHIAKQS-KRARPSSPYVVSYMMQVKYILIRNFWRIKNSASVTL 523
Query: 1174 VRLLFTIMTGILFGLIFWGVGAKSKKEQDLFNAMGSMYAAVTFIGVVNGASVQPIVAI-- 1231
++ + G +F+ + S + F +M+ A+ F +S+ I ++
Sbjct: 524 FQVFGNSAMAFILGSMFYKIQKGSSADTFYFRG-AAMFFAILFNAF---SSLLEIFSLYE 579
Query: 1232 ERTVFYRERAAGMYSAMPYALAQVIIELPHILVQAVVYGIIVYAMMGFEWTASKVLWNLF 1291
R + + R +Y A A VI E+P +V A+++ II Y ++ F A + F
Sbjct: 580 ARPITEKHRTYSLYHPSADAFASVISEIPPKIVTAILFNIIFYFLVNFRRDAGR-----F 634
Query: 1292 FTYFSFLYYTYYGMMTM-----AITPNPHVAGILSTSFYAIWCLFSGFIIPLSRIPIWWK 1346
F YF + M + ++T A + ++ +++GF IP +++ W K
Sbjct: 635 FFYFLINVIAVFAMSHLFRCVGSLTKTLQEAMVPASMLLLALSMYTGFAIPRTKMLGWSK 694
Query: 1347 WYYWICPVAWTLNGLVTSQY 1366
W ++I P+A+ L+ +++
Sbjct: 695 WIWYINPLAYLFESLMVNEF 714
>PDR5_YEAST (P33302) Suppressor of toxicity of sporidesmin
Length = 1511
Score = 445 bits (1145), Expect = e-124
Identities = 355/1286 (27%), Positives = 586/1286 (44%), Gaps = 137/1286 (10%)
Query: 154 ILQNVSGILKPRRMTLLLGPPGSGKTTLLLALAGIL-GKDLKQSGRVTYNGKGLEEFVPQ 212
IL+ + G L P + ++LG PGSG TTLL +++ G DL +++Y+G ++
Sbjct: 175 ILKPMDGCLNPGELLVVLGRPGSGCTTLLKSISSNTHGFDLGADTKISYSGYSGDDIKKH 234
Query: 213 RTS--AYVSQYDNHIGEMTVRETLAFSARCQGVGQNYEMLTELLRKEKESKIEPDPDINA 270
Y ++ D H+ +TV ETL AR K +++I+ D +
Sbjct: 235 FRGEVVYNAEADVHLPHLTVFETLVTVARL---------------KTPQNRIK-GVDRES 278
Query: 271 YMKEAAIEGHQNSVVIDYILKILGLDVCADTMVGDQMIRGISGGEKKRLTTGEMLVGPIK 330
Y A + + GL +T VG+ ++RG+SGGE+KR++ E+ + K
Sbjct: 279 YANHLA----------EVAMATYGLSHTRNTKVGNDIVRGVSGGERKRVSIAEVSICGSK 328
Query: 331 VLFMDEISNGLDSSTTFQIINSIKQSIHILNGTALVSLLQPAPETYELFDDIILLTDGQI 390
D + GLDS+T + I ++K I N +A V++ Q + + Y+LF+ + +L DG
Sbjct: 329 FQCWDNATRGLDSATALEFIRALKTQADISNTSATVAIYQCSQDAYDLFNKVCVLDDGYQ 388
Query: 391 VYQGPREYVLEFFESTGFKCPERKGVADFLQEVTSR--------------------KDQW 430
+Y GP + ++FE G+ CP R+ ADFL VTS K+
Sbjct: 389 IYYGPADKAKKYFEDMGYVCPSRQTTADFLTSVTSPSERTLNKDMLKKGIHIPQTPKEMN 448
Query: 431 QYWAREDEPYNFVTVKDFARAFELFHIGKQLGEELADPFDKSKFHSNVLITKKYGINKKE 490
YW + + D R ++ +E + + T Y + K
Sbjct: 449 DYWVKSPNYKELMKEVD-QRLLNDDEASREAIKEAHIAKQSKRARPSSPYTVSYMMQVKY 507
Query: 491 LLRACASRELLLMKRNSFVYIFKATQLTYLATLTTTLFLRTKMYHSTIEDAQTYM---GA 547
LL R + ++ N +F +A + ++F + D T+ A
Sbjct: 508 LL----IRNMWRLRNNIGFTLFMILGNCSMALILGSMFFKIMKKG----DTSTFYFRGSA 559
Query: 548 LFFTVTVAMFNGISELNMTIMKLPIFYKQRDLLFYPSWAYSLPPWILKIPITIIEVAIWE 607
+FF + F+ + E+ PI K R Y A + + +IP +I +
Sbjct: 560 MFFAILFNAFSSLLEIFSLYEARPITEKHRTYSLYHPSADAFASVLSEIPSKLIIAVCFN 619
Query: 608 CISYYAIGFDPNIGRFFKQSLVVLCINQMASALFRFMAALGRDIVVANTFGTFSLLAVTV 667
I Y+ + F N G FF L+ + S LFR + +L + + A + LLA+++
Sbjct: 620 IIFYFLVDFRRNGGVFFFYLLINIVAVFSMSHLFRCVGSLTKTLSEAMVPASMLLLALSM 679
Query: 668 LGGFVISREDVHKWFLWGYWSSPLMYGQNAIAVNEFLG----------HGWRKVAPNSNE 717
GF I ++ + +W W ++ +PL Y ++ +NEF G G +S E
Sbjct: 680 YTGFAIPKKKILRWSKWIWYINPLAYLFESLLINEFHGIKFPCAEYVPRGPAYANISSTE 739
Query: 718 TL--------GVSILKSRGFFPQAYWY-----WIGVGALIGYVFLFNFLFALALHFLSPF 764
++ G + F Y Y W G G + YV F F++ +
Sbjct: 740 SVCTVVGAVPGQDYVLGDDFIRGTYQYYHKDKWRGFGIGMAYVVFFFFVYLFLCEYNEGA 799
Query: 765 RKDQAGL-----------SQEKLQERNASTDEEFIQSQQQENSSNTKMDEEVSENKASSS 813
++ L + L E+NA+ E ++ + SS+ KM +E SE ++ +
Sbjct: 800 KQKGEILVFPRSIVKRMKKRGVLTEKNANDPENV--GERSDLSSDRKMLQESSEEESDTY 857
Query: 814 GRKGMVLPFQPLSLTFDDITYSVDMPQGMKNQGVTEDRLELLKGVSGAFRPGVLTALMGV 873
G G L + ++ Y V + + +L V G +PG LTALMG
Sbjct: 858 GEIG--LSKSEAIFHWRNLCYEVQ---------IKAETRRILNNVDGWVKPGTLTALMGA 906
Query: 874 SGAGKTTLMDVLAGIKTSGYIEGNIKVSGYQKNQKSFARISGYCEQFDIHSPNVTVYESL 933
SGAGKTTL+D LA T G I G+I V+G ++ KSF R GYC+Q D+H TV ESL
Sbjct: 907 SGAGKTTLLDCLAERVTMGVITGDILVNGIPRD-KSFPRSIGYCQQQDLHLKTATVRESL 965
Query: 934 LYSAWLRLSPEVDHATRKMFIEEVMELVELNSLREALVGLPGENGLSTEQRKRLTIAVEL 993
+SA+LR EV + ++EEV++++E+ +A+VG+ GE GL+ EQRKRLTI VEL
Sbjct: 966 RFSAYLRQPAEVSIEEKNRYVEEVIKILEMEKYADAVVGVAGE-GLNVEQRKRLTIGVEL 1024
Query: 994 VANPSI-IFMDEPTSGLDARAAAIVMRTVRNTVDTGRTVVCTIHQPSIDIFDSFDELLLL 1052
A P + +F+DEPTSGLD++ A + + ++ + G+ ++CTIHQPS + FD LL +
Sbjct: 1025 TAKPKLLVFLDEPTSGLDSQTAWSICQLMKKLANHGQAILCTIHQPSAILMQEFDRLLFM 1084
Query: 1053 KLGGEQIYAGPIGNQCSDLIQYFEAIQGVPTIKDGYNPATWMLEITSAGKEANLKVNFTD 1112
+ GG+ +Y G +G C +I YFE+ G NPA WMLE+ A ++ ++ +
Sbjct: 1085 QRGGKTVYFGDLGEGCKTMIDYFES-HGAHKCPADANPAEWMLEVVGAAPGSHANQDYYE 1143
Query: 1113 VYKNSELHRRNKQLI--QELSVPSQSS----KDLHFDAQYSQTFLAQCTYCLWKQHLSYW 1166
V++NSE +R + + E +P + S +D H ++SQ+ + Q + YW
Sbjct: 1144 VWRNSEEYRAVQSELDWMERELPKKGSITAAEDKH---EFSQSIIYQTKLVSIRLFQQYW 1200
Query: 1167 RNTSYTAVRLLFTIMTGILFGLIFWGVGAKSKKEQDLFNAMGSMYAAVTFIGVVNGASVQ 1226
R+ Y + + TI + G F+ G L M A F + N Q
Sbjct: 1201 RSPDYLWSKFILTIFNQLFIGFTFFKAGT------SLQGLQNQMLAVFMFTVIFNPILQQ 1254
Query: 1227 --PIVAIERTVF-YRERAAGMYSAMPYALAQVIIELPHILVQAVVYGIIVYAMMGFEWTA 1283
P +R ++ RER + +S + + AQ+ +E+P ++ + I Y +GF A
Sbjct: 1255 YLPSFVQQRDLYEARERPSRTFSWISFIFAQIFVEVPWNILAGTIAYFIYYYPIGFYSNA 1314
Query: 1284 SKV----LWNLFFTYFSFLYYTYYGMMTMAITPNPHV---AGILSTSFYAIWCLFSGFII 1336
S F FS +Y Y G M + + V A L++ + + F G +
Sbjct: 1315 SAAGQLHERGALFWLFSCAFYVYVGSMGLLVISFNQVAESAANLASLLFTMSLSFCGVMT 1374
Query: 1337 PLSRIPIWWKWYYWICPVAWTLNGLV 1362
S +P +W + Y + P+ + + L+
Sbjct: 1375 TPSAMPRFWIFMYRVSPLTYFIQALL 1400
Score = 128 bits (322), Expect = 1e-28
Identities = 135/553 (24%), Positives = 233/553 (41%), Gaps = 50/553 (9%)
Query: 853 ELLKGVSGAFRPGVLTALMGVSGAGKTTLMDVLAGIKTSGYIEG---NIKVSGYQKN--Q 907
++LK + G PG L ++G G+G TTL+ ++ T G+ G I SGY + +
Sbjct: 174 QILKPMDGCLNPGELLVVLGRPGSGCTTLLKSISS-NTHGFDLGADTKISYSGYSGDDIK 232
Query: 908 KSFARISGYCEQFDIHSPNVTVYESLLYSAWLRLSPE----VDHATRKMFIEEV-MELVE 962
K F Y + D+H P++TV+E+L+ A L+ VD + + EV M
Sbjct: 233 KHFRGEVVYNAEADVHLPHLTVFETLVTVARLKTPQNRIKGVDRESYANHLAEVAMATYG 292
Query: 963 LNSLREALVGLPGENGLSTEQRKRLTIAVELVANPSIIFMDEPTSGLDARAAAIVMRTVR 1022
L+ R VG G+S +RKR++IA + D T GLD+ A +R ++
Sbjct: 293 LSHTRNTKVGNDIVRGVSGGERKRVSIAEVSICGSKFQCWDNATRGLDSATALEFIRALK 352
Query: 1023 NTVDTGRT-VVCTIHQPSIDIFDSFDELLLLKLGGEQIYAGPIGNQCSDLIQYFEAIQGV 1081
D T I+Q S D +D F+++ +L G QIY GP +YFE + V
Sbjct: 353 TQADISNTSATVAIYQCSQDAYDLFNKVCVLD-DGYQIYYGP----ADKAKKYFEDMGYV 407
Query: 1082 ----PTIKDGYNPATWMLE-------------ITSAGKEAN----LKVNFTDVYKNSELH 1120
T D T E I KE N N+ ++ K +
Sbjct: 408 CPSRQTTADFLTSVTSPSERTLNKDMLKKGIHIPQTPKEMNDYWVKSPNYKELMKEVDQR 467
Query: 1121 RRN-----KQLIQELSVPSQSSKDLHFDAQYSQTFLAQCTYCLWKQHLSYWRNTSYTAVR 1175
N ++ I+E + Q SK + Y+ +++ Q Y L + N +T
Sbjct: 468 LLNDDEASREAIKEAHIAKQ-SKRARPSSPYTVSYMMQVKYLLIRNMWRLRNNIGFTLFM 526
Query: 1176 LLFTIMTGILFGLIFWGVGAKSKKEQDLFNAMGSMYAAVTFIGVVNGASVQPIVAI--ER 1233
+L ++ G +F+ + K F +M+ A+ F +S+ I ++ R
Sbjct: 527 ILGNCSMALILGSMFFKIMKKGDTSTFYFRG-SAMFFAILFNAF---SSLLEIFSLYEAR 582
Query: 1234 TVFYRERAAGMYSAMPYALAQVIIELPHILVQAVVYGIIVYAMMGFEWTASKVLWNLFFT 1293
+ + R +Y A A V+ E+P L+ AV + II Y ++ F + L
Sbjct: 583 PITEKHRTYSLYHPSADAFASVLSEIPSKLIIAVCFNIIFYFLVDFRRNGGVFFFYLLIN 642
Query: 1294 YFSFLYYTYYGMMTMAITPNPHVAGILSTSFYAIWCLFSGFIIPLSRIPIWWKWYYWICP 1353
+ ++ ++T A + ++ +++GF IP +I W KW ++I P
Sbjct: 643 IVAVFSMSHLFRCVGSLTKTLSEAMVPASMLLLALSMYTGFAIPKKKILRWSKWIWYINP 702
Query: 1354 VAWTLNGLVTSQY 1366
+A+ L+ +++
Sbjct: 703 LAYLFESLLINEF 715
>YN99_YEAST (P53756) Probable ATP-dependent transporter YNR070W
Length = 1333
Score = 435 bits (1119), Expect = e-121
Identities = 344/1305 (26%), Positives = 601/1305 (45%), Gaps = 128/1305 (9%)
Query: 154 ILQNVSGILKPRRMTLLLGPPGSGKTTLLLALAGILGKDLK--QSGRVTYNGKGLEEFVP 211
IL+NVS + K M L+LG PG+G T+ L + AG + +G ++Y+G +E +
Sbjct: 45 ILKNVSLLAKSGEMVLVLGRPGAGCTSFLKSAAGETSQFAGGVTTGHISYDGIPQKEMMQ 104
Query: 212 QRTS--AYVSQYDNHIGEMTVRETLAFSARCQGVGQNYEMLTELLRKEKESKIEPDPDIN 269
Y + D H +TV++TL F+ C+ P +N
Sbjct: 105 HYKPDVIYNGEQDVHFPHLTVKQTLDFAISCK---------------------MPAKRVN 143
Query: 270 AYMKEAAIEGHQNSVVIDYILKILGLDVCADTMVGDQMIRGISGGEKKRLTTGEMLVGPI 329
KE I ++ ++ KI GL DT VG+ I G+SGGE+KR++ E L
Sbjct: 144 NVTKEEYITANR-----EFYAKIFGLTHTFDTKVGNDFISGVSGGERKRVSIAEALAAKG 198
Query: 330 KVLFMDEISNGLDSSTTFQIINSIKQSIHILNGTALVSLLQPAPETYELFDDIILLTDGQ 389
+ D + GLDSST + +I+ ++L TALV++ Q + YE FD + +L G+
Sbjct: 199 SIYCWDNATRGLDSSTALEFARAIRTMTNLLGTTALVTVYQASENIYETFDKVTVLYAGR 258
Query: 390 IVYQGPREYVLEFFESTGFKCPERKGVADFLQEVTSRKDQWQYWAREDEPYNFVTVKDFA 449
++ G ++FE+ G+ CP R+ A++L +T E +P V A
Sbjct: 259 QIFCGKTTEAKDYFENMGYLCPPRQSTAEYLTAITDPNG-----LHEIKPGFEYQVPHTA 313
Query: 450 RAFELFHIGKQLGEELADPFDKSKFHSNVLITKK-------------------YGINKKE 490
FE + + L K K N TKK Y ++ E
Sbjct: 314 DEFEKYWLDSPEYARLKGEIQKYKHEVNTEWTKKTYNESMAQEKSKGTRKKSYYTVSYWE 373
Query: 491 LLRACASRELLLMKRNSFVYIFKATQLTYLATLTTTLFLRTKMYHSTIEDAQTYMGALFF 550
+R C R L + + + A +T +LF + S+ A + G LFF
Sbjct: 374 QIRLCTIRGFLRIYGDKSYTVINTCAAIAQAFITGSLFYQAP---SSTLGAFSRSGVLFF 430
Query: 551 TVTVAMFNGISELNMTIMKLPIFYKQRDLLFYPSWAYSLPPWILKIPITIIEVAIWECIS 610
++ G++ N++ PI K + Y A +L I P +I + + I
Sbjct: 431 SLLYYSLMGLA--NISFEHRPILQKHKVYSLYHPSAEALASTISSFPFRMIGLTFFIIIL 488
Query: 611 YYAIGFDPNIGRFFKQSLVVLCINQMASALFRFMAALGRDIVVANTFGTFSLLAVTVLGG 670
Y+ G + G FF L++ ++ ++LF+ +++L + AN+ +L++ +
Sbjct: 489 YFLAGLHRSAGAFFTMYLLLTMCSEAITSLFQMVSSLCDTLSQANSIAGVVMLSIAMYST 548
Query: 671 FVISREDVHKWFLWGYWSSPLMYGQNAIAVNEFLGH-------------GWRKVAPNS-- 715
++I +H WF W + P+ Y ++ EF G G+ + P +
Sbjct: 549 YMIQLPSMHPWFKWISYILPIRYAFESMLNAEFHGRHMDCGGTLVPSGPGFENILPENQV 608
Query: 716 ----NETLGVSILKSRGFFPQAYWY-----WIGVGALIGYVFLFNFLFALALHFLSPFRK 766
G S + + Y Y W G + ++ + L A+ + SP +
Sbjct: 609 CAFVGSRPGQSWVLGDDYLRAQYQYEYKNTWRNFGIMWCFLIGYIVLRAVFTEYKSPVKS 668
Query: 767 DQAGLSQEKLQERNASTDEEFIQSQQQENSSNTKMDEEVSENKASSSGRKGMVLPFQPLS 826
L +K +NA + +EN + + +++ E +SS F+ L
Sbjct: 669 GGDALVVKK-GTKNA-IQRSWSSKNDEENLNASIATQDMKE--IASSNDDSTSADFEGLE 724
Query: 827 LT----FDDITYSVDMPQGMKNQGVTEDRLELLKGVSGAFRPGVLTALMGVSGAGKTTLM 882
T + ++++++ G + +LL VSG PG LTAL+G SGAGKTTL+
Sbjct: 725 STGVFIWKNVSFTIPHSSGQR---------KLLDSVSGYCVPGTLTALIGESGAGKTTLL 775
Query: 883 DVLAGIKTSGYIEGNIKVSGYQKNQKSFARISGYCEQFDIHSPNVTVYESLLYSAWLRLS 942
+ LA + G I G++ V G + SF R +GY +Q D+H +TV ESL +SA +R
Sbjct: 776 NTLAQ-RNVGTITGDMLVDGLPMD-ASFKRRTGYVQQQDLHVAELTVKESLQFSARMRRP 833
Query: 943 PEVDHATRKMFIEEVMELVELNSLREALVGLPGENGLSTEQRKRLTIAVELVANPS-IIF 1001
+ A + ++E+++ ++E+ EALVG G GL+ EQRK+L+I VELV P ++F
Sbjct: 834 QSIPDAEKMEYVEKIISILEMQEFSEALVGEIG-YGLNVEQRKKLSIGVELVGKPDLLLF 892
Query: 1002 MDEPTSGLDARAAAIVMRTVRNTVDTGRTVVCTIHQPSIDIFDSFDELLLLKLGGEQIYA 1061
+DEPTSGLD+++A V++ ++ G++++CTIHQPS +F+ FD LLLL GG+ IY
Sbjct: 893 LDEPTSGLDSQSAWAVVKMLKRLALAGQSILCTIHQPSATLFEQFDRLLLLGKGGQTIYF 952
Query: 1062 GPIGNQCSDLIQYFEAIQGVPTIKDGYNPATWMLEITSAGKEANLKVNFTDVYKNSELHR 1121
G IG S +I+YFE G + NPA ++LE AG A+++ N+ D+++ S +
Sbjct: 953 GEIGKNSSSVIKYFEK-NGARKCQQNENPAEYILEAIGAGATASVQQNWPDIWQKSHEYA 1011
Query: 1122 RNKQLIQELSVPSQSSKDLHFDA----QYSQTFLAQCTYCLWKQHLSYWRNTSYTAVRLL 1177
+ I ++ + SS LH A +Y+ ++ Q + L + L++WRN +Y +++
Sbjct: 1012 NINEKINDM-IKDLSSTTLHKTATRASKYATSYSYQFHHVLKRSSLTFWRNLNYIMAKMM 1070
Query: 1178 FTIMTGILFGLIFWGVGAKSKKEQDLFNAMGSMYAAVTFIGVVNGASVQPIVAIERTVFY 1237
+++G+ G F+ VG + L N++ + + A+ + +
Sbjct: 1071 LLMISGLFIGFTFFHVGVNA---IGLQNSLFACFMAIVISAPATNQIQERATVAKELYEV 1127
Query: 1238 RERAAGMYSAMPYALAQVIIELPHILVQAVVYGIIVYAMMGFEWTASKVLWNLFFTYFSF 1297
RE + M+ + + ELP+ L+ + ++ + Y +G AS+ ++F+ ++
Sbjct: 1128 RESKSNMFHWSLLLITHYLNELPYHLLFSTIFFVSSYFPLGVFTEASRS--SVFYLNYAI 1185
Query: 1298 LYYTYY---GMMTMAITPNPHVAGILSTSFYAIWCLFSGFIIPLSRIPIWWKWYYWICPV 1354
L+ YY +M + ++PN A ++ + F G + P S +P +W + + + P
Sbjct: 1186 LFQLYYIGLALMILYMSPNLQSANVIVGFILSFLLSFCGAVQPASLMPGFWTFMWKLSPY 1245
Query: 1355 AWTLNGLV----------TSQYGHNMDTLDNGQSVEEFVRNYFGF 1389
+ L LV S+ ++ GQ+ EF + +F F
Sbjct: 1246 TYFLQNLVGLLMHDKPVRCSKKELSLFNPPVGQTCGEFTKPFFEF 1290
Score = 107 bits (266), Expect = 3e-22
Identities = 118/488 (24%), Positives = 214/488 (43%), Gaps = 74/488 (15%)
Query: 145 IPSPKKQLHILQNVSGILKPRRMTLLLGPPGSGKTTLLLALAGILGKDLKQSGRVTYNGK 204
IP Q +L +VSG P +T L+G G+GKTTLL LA Q T G
Sbjct: 738 IPHSSGQRKLLDSVSGYCVPGTLTALIGESGAGKTTLLNTLA--------QRNVGTITGD 789
Query: 205 GLEEFVP-----QRTSAYVSQYDNHIGEMTVRETLAFSARCQGVGQNYEMLTELLRKEKE 259
L + +P +R + YV Q D H+ E+TV+E+L FSAR +
Sbjct: 790 MLVDGLPMDASFKRRTGYVQQQDLHVAELTVKESLQFSARM-----------------RR 832
Query: 260 SKIEPDPDINAYMKEAAIEGHQNSVVIDYILKILGLDVCADTMVGDQMIRGISGGEKKRL 319
+ PD + Y ++ I+ IL + ++ +VG ++ G++ ++K+L
Sbjct: 833 PQSIPDAEKMEY--------------VEKIISILEMQEFSEALVG-EIGYGLNVEQRKKL 877
Query: 320 TTGEMLVG-PIKVLFMDEISNGLDSSTTFQIINSIKQSIHILNGTALVSLLQPAPETYEL 378
+ G LVG P +LF+DE ++GLDS + + ++ +K+ + + + L ++ QP+ +E
Sbjct: 878 SIGVELVGKPDLLLFLDEPTSGLDSQSAWAVVKMLKR-LALAGQSILCTIHQPSATLFEQ 936
Query: 379 FDDIILL-TDGQIVYQGP----REYVLEFFESTGF-KCPERKGVADFLQEVTSRKDQWQY 432
FD ++LL GQ +Y G V+++FE G KC + + A+++ E
Sbjct: 937 FDRLLLLGKGGQTIYFGEIGKNSSSVIKYFEKNGARKCQQNENPAEYILEAIGA------ 990
Query: 433 WAREDEPYNFVTVKDFARAFELFHIGKQLGEELADPFDKSKFHSNVLITKKYGINKKELL 492
A N+ + + ++ E +I +++ + + D + H KY +
Sbjct: 991 GATASVQQNWPDI--WQKSHEYANINEKINDMIKD-LSSTTLHKTATRASKYATSYSYQF 1047
Query: 493 RACASRELLLMKRNSFVYIFKATQLTYLATLTTTLFLRTKMYHSTIE--DAQTYMGALFF 550
R L RN YI L + + LF+ +H + Q + A F
Sbjct: 1048 HHVLKRSSLTFWRN-LNYIMAKMML----LMISGLFIGFTFFHVGVNAIGLQNSLFACFM 1102
Query: 551 TVTVA--MFNGISELNMTIMKLPIFYKQRDLLFYPSWAYSL-PPWILKIPITIIEVAIWE 607
+ ++ N I E +L + + +F+ W+ L ++ ++P ++ I+
Sbjct: 1103 AIVISAPATNQIQERATVAKELYEVRESKSNMFH--WSLLLITHYLNELPYHLLFSTIFF 1160
Query: 608 CISYYAIG 615
SY+ +G
Sbjct: 1161 VSSYFPLG 1168
>CDR2_CANAL (P78595) Multidrug resistance protein CDR2
Length = 1499
Score = 434 bits (1117), Expect = e-121
Identities = 349/1309 (26%), Positives = 598/1309 (45%), Gaps = 125/1309 (9%)
Query: 125 PTLFNFFVNVIEGCLNNLQIIPSPKKQLHILQNVSGILKPRRMTLLLGPPGSGKTTLLLA 184
PT+ N +N L+ P K IL+++ I++P +T++LG PG+G +TLL
Sbjct: 139 PTVTNALWKFTTEAINKLKK-PDDSKYFDILKSMDAIMRPGELTVVLGRPGAGCSTLLKT 197
Query: 185 LA-GILGKDLKQSGRVTYNGKGLEEFVPQRTS--AYVSQYDNHIGEMTVRETLAFSARCQ 241
+A G + + ++TY+G + Y ++ D H ++V +TL F+AR +
Sbjct: 198 IAVNTYGFHIGKESQITYDGLSPHDIERHYRGDVIYSAETDVHFPHLSVGDTLEFAARLR 257
Query: 242 GVGQNYEMLTELLRKEKESKIEPDPDINAYMKEAAIEGHQNSVVIDYILKILGLDVCADT 301
E + D Y K H SV + GL +T
Sbjct: 258 TPQNRGEGI----------------DRETYAK------HMASVY----MATYGLSHTRNT 291
Query: 302 MVGDQMIRGISGGEKKRLTTGEMLVGPIKVLFMDEISNGLDSSTTFQIINSIKQSIHILN 361
VG+ +RG+SGGE+KR++ E + + D + GLDS+T + I ++K S IL+
Sbjct: 292 NVGNDFVRGVSGGERKRVSIAEASLSGANIQCWDNATRGLDSATALEFIRALKTSATILD 351
Query: 362 GTALVSLLQPAPETYELFDDIILLTDGQIVYQGPREYVLEFFESTGFKCPERKGVADFLQ 421
T L+++ Q + + YELFD++++L +G ++ G E+FE+ G+KCP+R+ ADFL
Sbjct: 352 TTPLIAIYQCSQDAYELFDNVVVLYEGYQIFFGKASKAKEYFENMGWKCPQRQTTADFLT 411
Query: 422 EVTSRKDQWQYWAREDEPYNFVTVKDFARAFELFHIGKQLGEELADPFDK---------- 471
+T+ ++ ED+ V A+ FE F EL D+
Sbjct: 412 SLTNPAEREPLPGYEDK------VPRTAQEFETFWKNSPEYAELTKEIDEYFVECERSNT 465
Query: 472 ---------SKFHSNVLITKKYGINKKELLRACASRELLLMKRNSFVYIFKATQLTYLAT 522
K +N + Y ++ +R +R L MK + + + +
Sbjct: 466 GETYRESHVGKQSNNTRPSSPYTVSFFMQVRYVIARNFLRMKGDPSIPLISILSQLVMGL 525
Query: 523 LTTTLFLRTKMYHSTIEDAQTYMGALFFTVTVAMFNGISELNMTIMKLPIFYKQRDLLFY 582
+ ++F + T GALFF+V F+ + E+ PI K R Y
Sbjct: 526 ILASVFFNLRKSTDTF---YFRGGALFFSVLFNAFSSLLEILSLYEARPIVEKHRKYALY 582
Query: 583 PSWAYSLPPWILKIPITIIEVAIWECISYYAIGFDPNIGRFFKQSLVVLCINQMASALFR 642
A +L I ++P+ ++ + + Y+ + G FF L+ + S +FR
Sbjct: 583 RPSADALASIISELPVKLLMTMSFNIVYYFMVNLRRTAGNFFFYWLMCASCTLVMSHMFR 642
Query: 643 FMAALGRDIVVANTFGTFSLLAVTVLGGFVISREDVHKWFLWGYWSSPLMYGQNAIAVNE 702
+ A+ I A + T LLA+ + GFV+ + W W + +P+ Y ++ VNE
Sbjct: 643 SIGAVTTTIATAMSLSTVFLLAMIIYAGFVLPIPYILGWSRWIRYINPVTYIFESLMVNE 702
Query: 703 FLGHGW------------------RKVAPNSNETLGVSILKSRGFFPQAYWY-----WIG 739
F G + KV T G ++++ + AY + W
Sbjct: 703 FHGREFECGQYIPSGPGFENLPVENKVCTTVGSTPGSTVVQGTEYIKLAYQFYSSHKWRN 762
Query: 740 VGALIGY-VFLFNFLFALALHFLSPFRKDQAGL----SQEKLQERNASTDEEFIQSQQQE 794
G + + VF AL +K + L S +K + + A++++ I++
Sbjct: 763 FGITVAFAVFFLGVYVALTEFNKGASQKGEIVLFLKGSLKKHKRKTAASNKGDIEAGPVA 822
Query: 795 NSSNTKMD-EEVSENKASSSGRKGMV-LPFQPLSLTFDDITYSVDMPQGMKNQGVTEDRL 852
+ + + E V+ K + G G V P + D+TY V + + EDR+
Sbjct: 823 GKLDYQDEAEAVNNEKFTEKGSTGSVDFPENREIFFWRDLTYQVKIKK--------EDRV 874
Query: 853 ELLKGVSGAFRPGVLTALMGVSGAGKTTLMDVLAGIKTSGYI-EGNIKVSGYQKNQKSFA 911
+L V G +PG +TALMG SGAGKTTL++ L+ T+G I +G V+G+ + SF
Sbjct: 875 -ILDHVDGWVKPGQITALMGASGAGKTTLLNCLSERVTTGIITDGERLVNGHALD-SSFQ 932
Query: 912 RISGYCEQFDIHSPNVTVYESLLYSAWLRLSPEVDHATRKMFIEEVMELVELNSLREALV 971
R GY +Q D+H TV E+L +SA+LR S ++ + +++ V++L+E+ +ALV
Sbjct: 933 RSIGYVQQQDVHLETTTVREALQFSAYLRQSNKISKKEKDDYVDYVIDLLEMTDYADALV 992
Query: 972 GLPGENGLSTEQRKRLTIAVELVANPS-IIFMDEPTSGLDARAAAIVMRTVRNTVDTGRT 1030
G+ GE GL+ EQRKRLTI VELVA P ++F+DEPTSGLD++ A + + +R D G+
Sbjct: 993 GVAGE-GLNVEQRKRLTIGVELVAKPKLLLFLDEPTSGLDSQTAWSICKLMRKLADHGQA 1051
Query: 1031 VVCTIHQPSIDIFDSFDELLLLKLGGEQIYAGPIGNQCSDLIQYFEAIQGVPTIKDGYNP 1090
++CTIHQPS I FD+LL L+ GG Y G +G C +I YFE P K+ NP
Sbjct: 1052 ILCTIHQPSALIMAEFDKLLFLQKGGRTAYFGELGENCQTMINYFEKYGADPCPKEA-NP 1110
Query: 1091 ATWMLEITSAGKEANLKVNFTDVYKNSELHRRNKQLIQELSVP-SQSSKDLHFDA--QYS 1147
A WML++ A ++ K ++ +V++NS ++ ++ I + S+ +D +A +Y+
Sbjct: 1111 AEWMLQVVGAAPGSHAKQDYFEVWRNSSEYQAVREEINRMEAELSKLPRDNDPEALLKYA 1170
Query: 1148 QTFLAQCTYCLWKQHLSYWRNTSYTAVRLLFTIMTGILFGLIFWGVGAKSKKEQDLFNAM 1207
Q W+ + WR+ Y +L+ I + + G F+ K + +L
Sbjct: 1171 APLWKQYLLVSWRTIVQDWRSPGYIYSKLILVISSSLFIGFSFF------KSKNNLQGLQ 1224
Query: 1208 GSMYAAVTFIGVVNGASVQ--PIVAIERTVF-YRERAAGMYSAMPYALAQVIIELPHILV 1264
M A F Q P R V+ RE + +S + Q+ E+P +V
Sbjct: 1225 SQMLAVFMFFVPFTTFIDQMLPYFVKHRAVYEVREAPSRTFSWFAFIAGQITSEIPFQIV 1284
Query: 1265 QAVVYGIIVYAMMGFEWTASK---------VLWNLFFTYFSFLYYTYYGMMTMAITPNPH 1315
+ Y +G A ++W L + ++Y + G + +++
Sbjct: 1285 VGTISYFCWYYPVGLYANAEPTDSVNSRGVLMWMLLTAF--YVYTSTMGQLAISLNELID 1342
Query: 1316 VAGILSTSFYAIWCLFSGFIIPLSRIPIWWKWYYWICPVAWTLNGLVTS 1364
A L+T+ + + +F G + + IP +W + Y P + + ++++
Sbjct: 1343 NAANLATTLFTLCLMFCGVLAGPNVIPGFWIFMYRCNPFTYLIQAILST 1391
Score = 126 bits (317), Expect = 4e-28
Identities = 136/555 (24%), Positives = 245/555 (43%), Gaps = 58/555 (10%)
Query: 853 ELLKGVSGAFRPGVLTALMGVSGAGKTTLMDVLAGIKTSGYI---EGNIKVSGYQKN--Q 907
++LK + RPG LT ++G GAG +TL+ +A + T G+ E I G + +
Sbjct: 166 DILKSMDAIMRPGELTVVLGRPGAGCSTLLKTIA-VNTYGFHIGKESQITYDGLSPHDIE 224
Query: 908 KSFARISGYCEQFDIHSPNVTVYESLLYSAWLRLSPE----VDHATRKMFIEEV-MELVE 962
+ + Y + D+H P+++V ++L ++A LR +D T + V M
Sbjct: 225 RHYRGDVIYSAETDVHFPHLSVGDTLEFAARLRTPQNRGEGIDRETYAKHMASVYMATYG 284
Query: 963 LNSLREALVGLPGENGLSTEQRKRLTIAVELVANPSIIFMDEPTSGLDARAAAIVMRTVR 1022
L+ R VG G+S +RKR++IA ++ +I D T GLD+ A +R ++
Sbjct: 285 LSHTRNTNVGNDFVRGVSGGERKRVSIAEASLSGANIQCWDNATRGLDSATALEFIRALK 344
Query: 1023 NT---VDTGRTVVCTIHQPSIDIFDSFDELLLLKLGGEQIYAGPIGNQCSDLIQYFEAIQ 1079
+ +DT T + I+Q S D ++ FD +++L G QI+ G + S +YFE +
Sbjct: 345 TSATILDT--TPLIAIYQCSQDAYELFDNVVVL-YEGYQIFFG----KASKAKEYFENMG 397
Query: 1080 GVPTIKDGYNPATWMLEITSAGKEANL-----KV-----NFTDVYKNSELHRRNKQLIQE 1129
A ++ +T+ + L KV F +KNS + + I E
Sbjct: 398 W--KCPQRQTTADFLTSLTNPAEREPLPGYEDKVPRTAQEFETFWKNSPEYAELTKEIDE 455
Query: 1130 LSVPSQSS------KDLHFDAQ---------YSQTFLAQCTYCLWKQHLSYWRNTSYTAV 1174
V + S ++ H Q Y+ +F Q Y + + L + S +
Sbjct: 456 YFVECERSNTGETYRESHVGKQSNNTRPSSPYTVSFFMQVRYVIARNFLRMKGDPSIPLI 515
Query: 1175 RLLFTIMTGILFGLIFWGVGAKSKKEQDLFNAMGSMYAAVTFIGVVNG-ASVQPIVAI-- 1231
+L ++ G++ +F+ + +K D F G A+ F + N +S+ I+++
Sbjct: 516 SILSQLVMGLILASVFFNL----RKSTDTFYFRGG---ALFFSVLFNAFSSLLEILSLYE 568
Query: 1232 ERTVFYRERAAGMYSAMPYALAQVIIELPHILVQAVVYGIIVYAMMGFEWTASKVLWNLF 1291
R + + R +Y ALA +I ELP L+ + + I+ Y M+ TA +
Sbjct: 569 ARPIVEKHRKYALYRPSADALASIISELPVKLLMTMSFNIVYYFMVNLRRTAGNFFFYWL 628
Query: 1292 FTYFSFLYYTYYGMMTMAITPNPHVAGILSTSFYAIWCLFSGFIIPLSRIPIWWKWYYWI 1351
L ++ A+T A LST F +++GF++P+ I W +W +I
Sbjct: 629 MCASCTLVMSHMFRSIGAVTTTIATAMSLSTVFLLAMIIYAGFVLPIPYILGWSRWIRYI 688
Query: 1352 CPVAWTLNGLVTSQY 1366
PV + L+ +++
Sbjct: 689 NPVTYIFESLMVNEF 703
>BFR1_SCHPO (P41820) Brefeldin A resistance protein
Length = 1530
Score = 431 bits (1109), Expect = e-120
Identities = 350/1325 (26%), Positives = 592/1325 (44%), Gaps = 152/1325 (11%)
Query: 154 ILQNVSGILKPRRMTLLLGPPGSGKTTLLLALAGILGKDLKQSGRVTYNG---KGLEEFV 210
IL + + + ++LG PGSG +T L ++ + G Y+G +++F
Sbjct: 176 ILSHCHALANAGELVMVLGQPGSGCSTFLRSVTSDTVHYKRVEGTTHYDGIDKADMKKFF 235
Query: 211 PQRTSAYVSQYDNHIGEMTVRETLAFSARCQGVGQNYEMLTELLRKEKESKIEPDPDINA 270
P Y + D H +T ETL F+A+C+ LT R+E S+
Sbjct: 236 PGDL-LYSGENDVHFPSLTTAETLDFAAKCRTPNNRPCNLT---RQEYVSR--------- 282
Query: 271 YMKEAAIEGHQNSVVIDYILKILGLDVCADTMVGDQMIRGISGGEKKRLTTGEMLVGPIK 330
E H I GL +T VG+ +RG+SGGE+KR+T E
Sbjct: 283 -------ERH-------LIATAFGLTHTFNTKVGNDFVRGVSGGERKRVTISEGFATRPT 328
Query: 331 VLFMDEISNGLDSSTTFQIINSIKQSIHILNGTALVSLLQPAPETYELFDDIILLTDGQI 390
+ D + GLDSST F+ +N ++ + L T+ V+ Q + + Y+LFD I +L G+
Sbjct: 329 IACWDNSTRGLDSSTAFEFVNVLRTCANELKMTSFVTAYQASEKIYKLFDRICVLYAGRQ 388
Query: 391 VYQGPREYVLEFFESTGFKCPERKGVADFLQEVTSRKDQWQYWAREDEPYNFVTVKDFAR 450
+Y GP + ++F GF C R+ DFL ++ K ++ E+ T +F +
Sbjct: 389 IYYGPADKAKQYFLDMGFDCHPRETTPDFLTAISDPKARFPRKGFENRVPR--TPDEFEQ 446
Query: 451 AFELFHIGKQLGEEL--------------ADPFDKSKFHSNVLITKKYGINKKELLRACA 496
+ + L E+ ++ +K F S++ T K+ + ++ + +
Sbjct: 447 MWRNSSVYADLMAEMESYDKRWTETTPASSEAPEKDNFGSDISATTKHELYRQSAVAEKS 506
Query: 497 SRELLLMKRNSFVYIFKATQLTY--------------------LATLTTTLFLRTKMYHS 536
R +K S + + QL Y A L +L + + Y
Sbjct: 507 KR----VKDTSPYTVTFSQQLWYCLARSWERYINDPAYIGSMAFAFLFQSLIIGSIFYDM 562
Query: 537 TIEDAQTYM--GALFFTVTVAMFNGISELNMTIMKLPIFYKQRDLLFYPSWAYSLPPWIL 594
+ + G LFF++ +SE+ + PI K R Y A + I+
Sbjct: 563 KLNTVDVFSRGGVLFFSILFCALQSLSEIANMFSQRPIIAKHRASALYHPAADVISSLIV 622
Query: 595 KIPITIIEVAIWECISYYAIGFDPNIGRFFKQSLVVLCINQMASALFRFMAALGRDIVVA 654
+P I ++++ + Y+ G F+ L + SA FR +A + ++ A
Sbjct: 623 DLPFRFINISVFSIVLYFLTNLKRTAGGFWTYFLFLFIGATCMSAFFRSLAGIMPNVESA 682
Query: 655 NTFGTFSLLAVTVLGGFVISREDVHKWFLWGYWSSPLMYGQNAIAVNEF----------- 703
+ G +LA+ + G+ I DV WF W + PL +G ++ +NEF
Sbjct: 683 SALGGIGVLAIAIYTGYAIPNIDVGWWFRWIAYLDPLQFGFESLMINEFKARQFECSQLI 742
Query: 704 -LGHGW------RKVAPNSNETLGVSILKSRGFFPQAYWY-----WIGVGALIGYVFLFN 751
G G+ K+ P ++ G + + ++ Y W + +IGY
Sbjct: 743 PYGSGYDNYPVANKICPVTSAEPGTDYVDGSTYLYISFNYKTRQLWRNLAIIIGYYAFLV 802
Query: 752 FLFALALHFLS---------PFRKDQA-GLSQEKLQERNASTDEEFIQSQQQENSSNTKM 801
F+ +A L+ FR+ A + + E D E Q Q +
Sbjct: 803 FVNIVASETLNFNDLKGEYLVFRRGHAPDAVKAAVNEGGKPLDLETGQDTQGGDVVKESP 862
Query: 802 DEEVSENKASSSGRKGMVLPFQPLSLTFDDITYSVDMPQGMKNQGVTEDRLELLKGVSGA 861
D E NK KG + ++ ++ Y + + + LL GV G
Sbjct: 863 DNEEELNKEYEGIEKGHDI------FSWRNLNYDIQ---------IKGEHRRLLNGVQGF 907
Query: 862 FRPGVLTALMGVSGAGKTTLMDVLAGIKTSGYIEGNIKVSGYQKNQKSFARISGYCEQFD 921
PG LTALMG SGAGKTTL++VLA +G + G++ V+G + +F R +GY +Q D
Sbjct: 908 VVPGKLTALMGESGAGKTTLLNVLAQRVDTGVVTGDMLVNG-RGLDSTFQRRTGYVQQQD 966
Query: 922 IHSPNVTVYESLLYSAWLRLSPEVDHATRKMFIEEVMELVELNSLREALVGLPGENGLST 981
+H TV E+L +SA LR V + + ++E V++L+E+ S EA++G PG +GL+
Sbjct: 967 VHIGESTVREALRFSAALRQPASVPLSEKYEYVESVIKLLEMESYAEAIIGTPG-SGLNV 1025
Query: 982 EQRKRLTIAVELVANPS-IIFMDEPTSGLDARAAAIVMRTVRNTVDTGRTVVCTIHQPSI 1040
EQRKR TI VEL A P+ ++F+DEPTSGLD+++A ++ +R D G+ ++CTIHQPS
Sbjct: 1026 EQRKRATIGVELAAKPALLLFLDEPTSGLDSQSAWSIVCFLRKLADAGQAILCTIHQPSA 1085
Query: 1041 DIFDSFDELLLLKLGGEQIYAGPIGNQCSDLIQYFEAIQGVPTIKDGYNPATWMLEITSA 1100
+FD FD LLLL+ GG+ +Y G IG L+ YFE+ V DG NPA ++L++ A
Sbjct: 1086 VLFDQFDRLLLLQKGGKTVYFGDIGEHSKTLLNYFESHGAVHCPDDG-NPAEYILDVIGA 1144
Query: 1101 GKEANLKVNFTDVYKNSELHRRNKQLIQELSVPSQSSKD-----LHFDAQYSQTFLAQCT 1155
G A ++ +V+ NSE + + +++ +S+D + Y+ Q
Sbjct: 1145 GATATTNRDWHEVWNNSEERKAISAELDKINASFSNSEDKKTLSKEDRSTYAMPLWFQVK 1204
Query: 1156 YCLWKQHLSYWRNTSYTAVRLLFTIMTGILFGLIFWGVGAKSKKEQDLFNAMGSMYAAVT 1215
+ + SYWR S +L I G+ G F+ G + Q+ A+ A V
Sbjct: 1205 MVMTRNFQSYWREPSILMSKLALDIFAGLFIGFTFYNQGLGVQNIQNKLFAV--FMATVL 1262
Query: 1216 FIGVVNGASVQPIVAIERTVF-YRERAAGMYSAMPYALAQVIIELPHILVQAVV------ 1268
+ ++NG +QP R VF RE+ + +YS + + + +I+E+P LV +
Sbjct: 1263 AVPLING--LQPKFIELRNVFEVREKPSNIYSWVAFVFSAIIVEIPFNLVFGTLFFLCWF 1320
Query: 1269 YGIIVYAMMGFEWTASKVLWNLFFTYFSFLYYTYYGMMTMAITPNPHVAGILSTSFYAIW 1328
Y I Y + + W L+ F +Y++ +G + PN A ++++ +
Sbjct: 1321 YPIKFYKHIHHPGDKTGYAWLLYM--FFQMYFSTFGQAVASACPNAQTASVVNSLLFTFV 1378
Query: 1329 CLFSGFIIPLSRIPIWWKWYYWICPVAWTLNGLVTSQY--------GHNMDTLD--NGQS 1378
F+G + P S + +W W + + P + + GL++ H M T++ +GQ+
Sbjct: 1379 ITFNGVLQPNSNLVGFWHWMHSLTPFTYLIEGLLSDLVHGLPVECKSHEMLTINPPSGQT 1438
Query: 1379 VEEFV 1383
E++
Sbjct: 1439 CGEYM 1443
>CDR1_CANAL (P43071) Multidrug resistance protein CDR1
Length = 1501
Score = 426 bits (1096), Expect = e-118
Identities = 348/1283 (27%), Positives = 591/1283 (45%), Gaps = 130/1283 (10%)
Query: 154 ILQNVSGILKPRRMTLLLGPPGSGKTTLLLALA-GILGKDLKQSGRVTYNGKGLEEFVPQ 212
IL+++ I++P +T++LG PG+G +TLL +A G + + ++TY+G +
Sbjct: 169 ILKSMDAIMRPGELTVVLGRPGAGCSTLLKTIAVNTYGFHIGKESQITYDGLSPHDIERH 228
Query: 213 RTS--AYVSQYDNHIGEMTVRETLAFSARCQGVGQNYEMLTELLRKEKESKIEPDPDINA 270
Y ++ D H ++V +TL F+AR + E + D
Sbjct: 229 YRGDVIYSAETDVHFPHLSVGDTLEFAARLRTPQNRGEGI----------------DRET 272
Query: 271 YMKEAAIEGHQNSVVIDYILKILGLDVCADTMVGDQMIRGISGGEKKRLTTGEMLVGPIK 330
Y K H SV + GL +T VG+ +RG+SGGE+KR++ E +
Sbjct: 273 YAK------HMASVY----MATYGLSHTRNTNVGNDFVRGVSGGERKRVSIAEASLSGAN 322
Query: 331 VLFMDEISNGLDSSTTFQIINSIKQSIHILNGTALVSLLQPAPETYELFDDIILLTDGQI 390
+ D + GLDS+T + I ++K S IL+ T L+++ Q + + Y+LFD +++L +G
Sbjct: 323 IQCWDNATRGLDSATALEFIRALKTSAVILDTTPLIAIYQCSQDAYDLFDKVVVLYEGYQ 382
Query: 391 VYQGPREYVLEFFESTGFKCPERKGVADFLQEVTSRKDQWQYWAREDEPYNFVTVKDFAR 450
++ G E+FE G+KCP+R+ ADFL +T+ ++ ED+ V A+
Sbjct: 383 IFFGKATKAKEYFEKMGWKCPQRQTTADFLTSLTNPAEREPLPGYEDK------VPRTAQ 436
Query: 451 AFELFHIGKQLGEELADPFDK-------------------SKFHSNVLITKKYGINKKEL 491
FE + EL D+ +K +N Y ++
Sbjct: 437 EFETYWKNSPEYAELTKEIDEYFVECERSNTRETYRESHVAKQSNNTRPASPYTVSFFMQ 496
Query: 492 LRACASRELLLMKRNSFVYIFKATQLTYLATLTTTLFLRTKMYHSTIEDAQTYM--GALF 549
+R +R L MK + + IF + L L L + Y+ + Y A+F
Sbjct: 497 VRYGVARNFLRMKGDPSIPIF-----SVFGQLVMGLILSSVFYNLSQTTGSFYYRGAAMF 551
Query: 550 FTVTVAMFNGISELNMTIMKLPIFYKQRDLLFYPSWAYSLPPWILKIPITIIEVAIWECI 609
F V F+ + E+ PI K + Y A +L I ++P+ + + +
Sbjct: 552 FAVLFNAFSSLLEIMSLFEARPIVEKHKKYALYRPSADALASIISELPVKLAMSMSFNFV 611
Query: 610 SYYAIGFDPNIGRFFKQSLVVLCINQMASALFRFMAALGRDIVVANTFGTFSLLAVTVLG 669
Y+ + F N GRFF L+ + + S LFR + A+ I A T T LLA+ +
Sbjct: 612 FYFMVNFRRNPGRFFFYWLMCIWCTFVMSHLFRSIGAVSTSISGAMTPATVLLLAMVIYT 671
Query: 670 GFVISREDVHKWFLWGYWSSPLMYGQNAIAVNEFLGH------------GWRKVAPNSNE 717
GFVI + W W + +P+ Y ++ VNEF G G+ ++ SN+
Sbjct: 672 GFVIPTPSMLGWSRWINYINPVGYVFESLMVNEFHGREFQCAQYVPSGPGYENIS-RSNQ 730
Query: 718 TL-------GVSILKSRGFFPQAYWY-----WIGVGALIGY-VFLFNFLFALALHFLSPF 764
G ++ + AY Y W +G IG+ VF AL
Sbjct: 731 VCTAVGSVPGNEMVSGTNYLAGAYQYYNSHKWRNLGITIGFAVFFLAIYIALTEFNKGAM 790
Query: 765 RKDQAGL----SQEKLQERNASTDEEFIQSQQQENSSNTKMD-EEVSENKASSSGRKGMV 819
+K + L S +K + + A++++ I++ + + + E V+ K + G G V
Sbjct: 791 QKGEIVLFLKGSLKKHKRKTAASNKGDIEAGPVAGKLDYQDEAEAVNNEKFTEKGSTGSV 850
Query: 820 -LPFQPLSLTFDDITYSVDMPQGMKNQGVTEDRLELLKGVSGAFRPGVLTALMGVSGAGK 878
P + D+TY V + + EDR+ +L V G +PG +TALMG SGAGK
Sbjct: 851 DFPENREIFFWRDLTYQVKIKK--------EDRV-ILDHVDGWVKPGQITALMGASGAGK 901
Query: 879 TTLMDVLAGIKTSGYI-EGNIKVSGYQKNQKSFARISGYCEQFDIHSPNVTVYESLLYSA 937
TTL++ L+ T+G I +G V+G+ + SF R GY +Q D+H P TV E+L +SA
Sbjct: 902 TTLLNCLSERVTTGIITDGERLVNGHALD-SSFQRSIGYVQQQDVHLPTSTVREALQFSA 960
Query: 938 WLRLSPEVDHATRKMFIEEVMELVELNSLREALVGLPGENGLSTEQRKRLTIAVELVANP 997
+LR S ++ + +++ V++L+E+ +ALVG+ GE GL+ EQRKRLTI VELVA P
Sbjct: 961 YLRQSNKISKKEKDDYVDYVIDLLEMTDYADALVGVAGE-GLNVEQRKRLTIGVELVAKP 1019
Query: 998 S-IIFMDEPTSGLDARAAAIVMRTVRNTVDTGRTVVCTIHQPSIDIFDSFDELLLLKLGG 1056
++F+DEPTSGLD++ A + + +R D G+ ++CTIHQPS I FD LL L+ GG
Sbjct: 1020 KLLLFLDEPTSGLDSQTAWSICKLMRKLADHGQAILCTIHQPSALIMAEFDRLLFLQKGG 1079
Query: 1057 EQIYAGPIGNQCSDLIQYFEAIQGVPTIKDGYNPATWMLEITSAGKEANLKVNFTDVYKN 1116
Y G +G C +I YFE P K+ NPA WML++ A ++ K ++ +V++N
Sbjct: 1080 RTAYFGELGENCQTMINYFEKYGADPCPKEA-NPAEWMLQVVGAAPGSHAKQDYFEVWRN 1138
Query: 1117 SELHRRNKQLIQELSVP-SQSSKDLHFDA--QYSQTFLAQCTYCLWKQHLSYWRNTSYTA 1173
S ++ ++ I + S+ +D +A +Y+ Q W+ + WR+ Y
Sbjct: 1139 SSEYQAVREEINRMEAELSKLPRDNDPEALLKYAAPLWKQYLLVSWRTIVQDWRSPGYIY 1198
Query: 1174 VRLLFTIMTGILFGLIFWGVGAKSKKEQDLFNAMGSMYAAVTFIGVVNGASVQ--PIVAI 1231
++ + + G F+ K + ++ M++ F N Q P
Sbjct: 1199 SKIFLVVSAALFNGFSFF------KAKNNMQGLQNQMFSVFMFFIPFNTLVQQMLPYFVK 1252
Query: 1232 ERTVF-YRERAAGMYSAMPYALAQVIIELPHILVQAVVYGIIVYAMMGFEWTASK----- 1285
+R V+ RE + +S + Q+ E+P+ + + Y +G A+
Sbjct: 1253 QRDVYEVREAPSRTFSWFAFIAGQITSEIPYQVAVGTIAFFCWYYPLGLYNNATPTDSVN 1312
Query: 1286 ----VLWNLFFTYFSFLYYTYYGMMTMAITPNPHVAGILSTSFYAIWCLFSGFIIPLSRI 1341
++W L + ++Y G + M+ + A L+T + + F G + +
Sbjct: 1313 PRGVLMWMLVTAF--YVYTATMGQLCMSFSELADNAANLATLLFTMCLNFCGVLAGPDVL 1370
Query: 1342 PIWWKWYYWICPVAWTLNGLVTS 1364
P +W + Y P + + ++++
Sbjct: 1371 PGFWIFMYRCNPFTYLVQAMLST 1393
Score = 112 bits (279), Expect = 9e-24
Identities = 126/556 (22%), Positives = 240/556 (42%), Gaps = 60/556 (10%)
Query: 853 ELLKGVSGAFRPGVLTALMGVSGAGKTTLMDVLAGIKTSGY---IEGNIKVSGYQKN--Q 907
++LK + RPG LT ++G GAG +TL+ +A + T G+ E I G + +
Sbjct: 168 DILKSMDAIMRPGELTVVLGRPGAGCSTLLKTIA-VNTYGFHIGKESQITYDGLSPHDIE 226
Query: 908 KSFARISGYCEQFDIHSPNVTVYESLLYSAWLRLSPE-----VDHATRKMFIEEV-MELV 961
+ + Y + D+H P+++V ++L ++A LR +P+ +D T + V M
Sbjct: 227 RHYRGDVIYSAETDVHFPHLSVGDTLEFAARLR-TPQNRGEGIDRETYAKHMASVYMATY 285
Query: 962 ELNSLREALVGLPGENGLSTEQRKRLTIAVELVANPSIIFMDEPTSGLDARAAAIVMRTV 1021
L+ R VG G+S +RKR++IA ++ +I D T GLD+ A +R +
Sbjct: 286 GLSHTRNTNVGNDFVRGVSGGERKRVSIAEASLSGANIQCWDNATRGLDSATALEFIRAL 345
Query: 1022 R-NTVDTGRTVVCTIHQPSIDIFDSFDELLLLKLGGEQIYAGPIGNQCSDLIQYFEAIQG 1080
+ + V T + I+Q S D +D FD++++L G QI+ G + + +YFE +
Sbjct: 346 KTSAVILDTTPLIAIYQCSQDAYDLFDKVVVL-YEGYQIFFG----KATKAKEYFEKMGW 400
Query: 1081 VPTIKDGYNPATWMLEITSAGKEANL-----KV-----NFTDVYKNS------------- 1117
A ++ +T+ + L KV F +KNS
Sbjct: 401 --KCPQRQTTADFLTSLTNPAEREPLPGYEDKVPRTAQEFETYWKNSPEYAELTKEIDEY 458
Query: 1118 --ELHRRNKQLIQELSVPSQSSKDLHFDAQYSQTFLAQCTYCLWKQHLSYWRNTSYTAVR 1175
E R N + S ++ S + + Y+ +F Q Y + + L + S
Sbjct: 459 FVECERSNTRETYRESHVAKQSNNTRPASPYTVSFFMQVRYGVARNFLRMKGDPSIPIFS 518
Query: 1176 LLFTIMTGILFGLIFWGVGAKSKKEQDLFNAMGSMYAAVTFIGVVNGASVQPIVAIERTV 1235
+ ++ G++ +F+ + S+ + +M+ AV F + + + R +
Sbjct: 519 VFGQLVMGLILSSVFYNL---SQTTGSFYYRGAAMFFAVLFNAFSSLLEIMSLFE-ARPI 574
Query: 1236 FYRERAAGMYSAMPYALAQVIIELPHILVQAVVYGIIVYAMMGFEWTASKVLWNLFFTYF 1295
+ + +Y ALA +I ELP L ++ + + Y M+ F + FF Y+
Sbjct: 575 VEKHKKYALYRPSADALASIISELPVKLAMSMSFNFVFYFMVNFRRNPGR-----FFFYW 629
Query: 1296 SFLYYTYYGMMTM-----AITPNPHVAGILSTSFYAIWCLFSGFIIPLSRIPIWWKWYYW 1350
+ + M + A++ + A +T +++GF+IP + W +W +
Sbjct: 630 LMCIWCTFVMSHLFRSIGAVSTSISGAMTPATVLLLAMVIYTGFVIPTPSMLGWSRWINY 689
Query: 1351 ICPVAWTLNGLVTSQY 1366
I PV + L+ +++
Sbjct: 690 INPVGYVFESLMVNEF 705
Score = 98.2 bits (243), Expect = 1e-19
Identities = 89/305 (29%), Positives = 144/305 (47%), Gaps = 50/305 (16%)
Query: 149 KKQLHILQNVSGILKPRRMTLLLGPPGSGKTTLLLALAGILGKDLKQSGRVTYNGKGLEE 208
K+ IL +V G +KP ++T L+G G+GKTTLL L+ + + G NG L+
Sbjct: 872 KEDRVILDHVDGWVKPGQITALMGASGAGKTTLLNCLSERVTTGIITDGERLVNGHALDS 931
Query: 209 FVPQRTSAYVSQYDNHIGEMTVRETLAFSARCQGVGQNYEMLTELLRKEKESKIEPDPDI 268
QR+ YV Q D H+ TVRE L FSA L + K SK E D
Sbjct: 932 SF-QRSIGYVQQQDVHLPTSTVREALQFSA-------------YLRQSNKISKKEKDD-- 975
Query: 269 NAYMKEAAIEGHQNSVVIDYILKILGLDVCADTMVGDQMIRGISGGEKKRLTTG-EMLVG 327
+DY++ +L + AD +VG G++ ++KRLT G E++
Sbjct: 976 ----------------YVDYVIDLLEMTDYADALVG-VAGEGLNVEQRKRLTIGVELVAK 1018
Query: 328 PIKVLFMDEISNGLDSSTTFQIINSIKQSIHILNGTA-LVSLLQPAPETYELFDDIILL- 385
P +LF+DE ++GLDS T + I +++ +G A L ++ QP+ FD ++ L
Sbjct: 1019 PKLLLFLDEPTSGLDSQTAWSICKLMRKLAD--HGQAILCTIHQPSALIMAEFDRLLFLQ 1076
Query: 386 TDGQIVYQGPR----EYVLEFFESTGF-KCPERKGVADFLQEVT-------SRKDQWQYW 433
G+ Y G + ++ +FE G CP+ A+++ +V +++D ++ W
Sbjct: 1077 KGGRTAYFGELGENCQTMINYFEKYGADPCPKEANPAEWMLQVVGAAPGSHAKQDYFEVW 1136
Query: 434 AREDE 438
E
Sbjct: 1137 RNSSE 1141
>PDRA_YEAST (P51533) ATP-dependent permease PDR10
Length = 1564
Score = 420 bits (1079), Expect = e-116
Identities = 346/1318 (26%), Positives = 594/1318 (44%), Gaps = 165/1318 (12%)
Query: 154 ILQNVSGILKPRRMTLLLGPPGSGKTTLLLALA-GILGKDLKQSGRVTYNGKGLEEFVPQ 212
IL+ + G + P + ++LG PG+G TTLL +++ G + +TYNG +E
Sbjct: 195 ILKPMDGCINPGELLVVLGRPGAGCTTLLKSISVNTHGFKISPDTIITYNGFSNKEIKNH 254
Query: 213 RTS--AYVSQYDNHIGEMTVRETLAFSARCQGVGQNYEMLTELLRKEKESKIEP-DPDIN 269
Y ++ D HI +TV +TL AR K ++I+ D D
Sbjct: 255 YRGEVVYNAESDIHIPHLTVFQTLYTVARL---------------KTPRNRIKGVDRDTF 299
Query: 270 A-YMKEAAIEGHQNSVVIDYILKILGLDVCADTMVGDQMIRGISGGEKKRLTTGEMLVGP 328
A +M E A+ + GL ADT VG+ +RG+SGGE+KR++ E+ +
Sbjct: 300 AKHMTEVAMATY-------------GLSHTADTKVGNDFVRGVSGGERKRVSIAEVSICG 346
Query: 329 IKVLFMDEISNGLDSSTTFQIINSIKQSIHILNGTALVSLLQPAPETYELFDDIILLTDG 388
K D + GLDS+T + I ++K I A V++ Q + + Y+LFD + +L DG
Sbjct: 347 SKFQCWDNATRGLDSATALEFIKALKTQATITKSAATVAIYQCSKDAYDLFDKVCVLYDG 406
Query: 389 QIVYQGPREYVLEFFESTGFKCPERKGVADFLQEVTSRKDQW------------------ 430
++ GP + ++F+ G+ CPER+ AD+L +TS ++
Sbjct: 407 YQIFFGPSKQAKKYFQRMGYVCPERQTTADYLTSITSPSERIKDKDMVKHGIMIPQTAYE 466
Query: 431 --QYWAREDEPYNFVTVKDFARAFELFHIGKQLGEELADPFDKSKFHSNVLITKK----- 483
QYW + +E Y + V+ + K L + + ++ K N I K+
Sbjct: 467 MNQYWIQSEE-YKQLQVQ----------VNKHLDTDSSQQREQIK---NAHIAKQSKRAR 512
Query: 484 ----YGINKKELLRACASRELLLMKRNSFVYIFKATQLTYLATLTTTLFLRTKMYHSTIE 539
Y ++ ++ R++ +K + + +F +A + ++F + ST
Sbjct: 513 PSSPYTVSFFLQVKYILIRDIWRIKNDPSIQLFTVLSHAAMALILGSMFYEVML--STTT 570
Query: 540 DAQTYMGA-LFFTVTVAMFNGISELNMTIMKLPIFYKQRDLLFYPSWAYSLPPWILKIPI 598
Y GA +FF + F+ + E+ PI K + Y A + +P
Sbjct: 571 TTFYYRGAAIFFAILFNAFSSLLEIFSLYETRPITEKHKTYSLYRPSADAFASTFSDVPT 630
Query: 599 TIIEVAIWECISYYAIGFDPNIGRFFKQSLVVLCINQMASALFRFMAALGRDIVVANTFG 658
+ + Y+ I + G FF L+ + S LFR + ++ + + A
Sbjct: 631 KLATAVTFNIPYYFLINLKRDAGAFFFYFLINIITVFAMSHLFRCIGSVSKTLPQAMVPA 690
Query: 659 TFSLLAVTVLGGFVISREDVHKWFLWGYWSSPLMYGQNAIAVNEFLGHGWRKV-----AP 713
+ LLA + GF I R + W W + +PL Y ++ +NEF G + P
Sbjct: 691 SVLLLAFAMYTGFAIPRVQMLGWSKWISYINPLSYLFESLMINEFHGRNFPCAQYIPSGP 750
Query: 714 NSNETLGVSILKSR-------------GFFPQAYWY-----WIGVGALIGYVFLFNFLFA 755
N G + S F Y Y W VG + Y+ F FL+
Sbjct: 751 NYVNATGDEVTCSALGSIPGNNYVSGDDFIQTNYGYRHKNKWRSVGIGLAYIIFFLFLYL 810
Query: 756 LALHFLSPFRKDQAGL----SQEKLQERNASTDEEFIQSQQQENSSNTKMDEEVSENKAS 811
+ +++ L S K ++ E+ ++Q ++S+ + D E++ N ++
Sbjct: 811 FFCEYNEGAKQNGEMLVFPHSVVKKMKKKGIVSEKKKKNQPTLSTSDAEKDVEMNNNSSA 870
Query: 812 SSGRKGMVLPFQPLSLTFDDITYSVD---MPQGMKNQG---------------------- 846
+ R L ++ +D T + + P +Q
Sbjct: 871 TDSR---FLRDSDAAIMGNDKTVAKEHYSSPSSSASQSNSFSKSDDIELSKSQAIFHWKN 927
Query: 847 ------VTEDRLELLKGVSGAFRPGVLTALMGVSGAGKTTLMDVLAGIKTSGYIEGNIKV 900
+ + +L V G +PG LTAL+G SGAGKTTL+D LA T G I G++ V
Sbjct: 928 LCYDIPIKNGKRRILDNVDGWVKPGTLTALIGASGAGKTTLLDCLAERTTMGLITGDVFV 987
Query: 901 SGYQKNQKSFARISGYCEQFDIHSPNVTVYESLLYSAWLRLSPEVDHATRKMFIEEVMEL 960
G ++Q SF R GYC+Q D+H TV ESL +SA+LR + +V + ++EEV+E+
Sbjct: 988 DGRPRDQ-SFPRSIGYCQQQDLHLKTATVRESLRFSAYLRQADDVSIEEKDKYVEEVIEV 1046
Query: 961 VELNSLREALVGLPGENGLSTEQRKRLTIAVELVANPSI-IFMDEPTSGLDARAAAIVMR 1019
+E+ +A+VG+PGE GL+ EQRKRLTI VEL A P + +F+DEPTSGLD++ A +
Sbjct: 1047 LEMKLYADAIVGVPGE-GLNVEQRKRLTIGVELAAKPKLLVFLDEPTSGLDSQTAWSTCQ 1105
Query: 1020 TVRNTVDTGRTVVCTIHQPSIDIFDSFDELLLLKLGGEQIYAGPIGNQCSDLIQYFEAIQ 1079
++ G+ ++CTIHQPS + FD LL L+ GG+ +Y G +G C +I YFEA
Sbjct: 1106 LMKKLASRGQAILCTIHQPSALLMQEFDRLLFLQEGGQTVYFGELGKGCKTMINYFEA-H 1164
Query: 1080 GVPTIKDGYNPATWMLEITSAGKEANLKVNFTDVYKNSELHRRNKQLI--QELSVPSQSS 1137
G NPA WMLEI A + ++ ++++SE +R ++ + E +P ++
Sbjct: 1165 GAHKCPPDANPAEWMLEIVGAAPGTHASQDYFAIWRDSEEYREMQKELDWMERELPKRTE 1224
Query: 1138 KDLHFD-AQYSQTFLAQCTYCLWKQHLSYWRNTSYTAVRLLFTIMTGILFGLIFWGVGAK 1196
+ + +++ + L Q ++ YWR Y + TI++ + G F+
Sbjct: 1225 GSSNEEQKEFATSTLYQIKLVSYRLFHQYWRTPFYLWSKFFSTIVSELFIGFTFF----- 1279
Query: 1197 SKKEQDLFNAMGSMYAAVTFIGVVNGASVQ--PIVAIERTVF-YRERAAGMYSAMPYALA 1253
K L M A F V N Q P+ +R ++ RER + +S + ++
Sbjct: 1280 -KANTSLQGLQNQMLAIFMFTVVFNPILQQYLPLFVQQRELYEARERPSRTFSWKAFIVS 1338
Query: 1254 QVIIELPHILVQAVVYGIIVYAMMGFEWTAS--------KVLWNLFFTYFSFLYYTYYGM 1305
Q+++E+P L+ + + Y +GF AS L+ LF F ++Y + G+
Sbjct: 1339 QILVEIPWNLLAGTIAFFVYYYPVGFYRNASYANQLHERGALFWLFACAF-YVYISSMGV 1397
Query: 1306 MTMAITPNPHVAGILSTSFYAIWCLFSGFIIPLSRIPIWWKWYYWICPVAWTLNGLVT 1363
+ ++ A L++ F+ + F G + + +P +W + Y + P+ + ++ L++
Sbjct: 1398 LVISCIEIAENAANLASLFFIMSLSFCGVLATPNILPRFWIFMYRVSPLTYLIDALLS 1455
Score = 105 bits (263), Expect = 7e-22
Identities = 146/610 (23%), Positives = 274/610 (43%), Gaps = 101/610 (16%)
Query: 145 IPSPKKQLHILQNVSGILKPRRMTLLLGPPGSGKTTLLLALAGILGKDLKQSGRVTYNGK 204
IP + IL NV G +KP +T L+G G+GKTTLL LA L +G V +G+
Sbjct: 932 IPIKNGKRRILDNVDGWVKPGTLTALIGASGAGKTTLLDCLAERTTMGL-ITGDVFVDGR 990
Query: 205 GLEEFVPQRTSAYVSQYDNHIGEMTVRETLAFSARCQGVGQNYEMLTELLRKEKESKIEP 264
++ P R+ Y Q D H+ TVRE+L FSA LR+ + IE
Sbjct: 991 PRDQSFP-RSIGYCQQQDLHLKTATVRESLRFSA--------------YLRQADDVSIE- 1034
Query: 265 DPDINAYMKEAAIEGHQNSVVIDYILKILGLDVCADTMVGDQMIRGISGGEKKRLTTG-E 323
+ ++ ++++L + + AD +VG G++ ++KRLT G E
Sbjct: 1035 ----------------EKDKYVEEVIEVLEMKLYADAIVGVPG-EGLNVEQRKRLTIGVE 1077
Query: 324 MLVGPIKVLFMDEISNGLDSSTTFQIINSIKQSIHILNGTALVSLLQPAPETYELFDDII 383
+ P ++F+DE ++GLDS T + +K+ + L ++ QP+ + FD ++
Sbjct: 1078 LAAKPKLLVFLDEPTSGLDSQTAWSTCQLMKK-LASRGQAILCTIHQPSALLMQEFDRLL 1136
Query: 384 LLTD-GQIVYQGPR----EYVLEFFESTG-FKCPERKGVADFLQEVT-------SRKDQW 430
L + GQ VY G + ++ +FE+ G KCP A+++ E+ + +D +
Sbjct: 1137 FLQEGGQTVYFGELGKGCKTMINYFEAHGAHKCPPDANPAEWMLEIVGAAPGTHASQDYF 1196
Query: 431 QYWAREDEPYNFVTVKDFARAFELFHIGKQLGEELADPFDKSKFHSNVLITKKYGINKKE 490
W R+ E Y + EL + ++L + ++ + K++ +
Sbjct: 1197 AIW-RDSEEYREMQK-------ELDWMERELPKRTEGSSNEEQ--------KEFATSTLY 1240
Query: 491 LLRACASRELLLMKRNSFVYIFKATQLTYLATLTTTLFLRTKMY--HSTIEDAQTYMGAL 548
++ + R R F Y++ + +T+ + LF+ + +++++ Q M A+
Sbjct: 1241 QIKLVSYRLFHQYWRTPF-YLWS----KFFSTIVSELFIGFTFFKANTSLQGLQNQMLAI 1295
Query: 549 F-FTVTVAMFNGISELNMTIMKLPIFYKQRDLLFYP-------SW-AYSLPPWILKIPIT 599
F FTV +FN I + LP+F +QR+L SW A+ + +++IP
Sbjct: 1296 FMFTV---VFNPILQ-----QYLPLFVQQRELYEARERPSRTFSWKAFIVSQILVEIPWN 1347
Query: 600 IIEVAIWECISYYAIGFDPNIGRFFKQSLVVLCINQMASALFRFMAALGRDIV------- 652
++ I + YY +GF N + A A + +++++G ++
Sbjct: 1348 LLAGTIAFFVYYYPVGFYRNASYANQLHERGALFWLFACAFYVYISSMGVLVISCIEIAE 1407
Query: 653 -VANTFGTFSLLAVTVLGGFVISREDVHKWFLWGYWSSPLMYGQNAIAVNEFLGHGWRKV 711
AN F +++++ G + + + +++++ Y SPL Y +A+ +G V
Sbjct: 1408 NAANLASLFFIMSLSFC-GVLATPNILPRFWIFMYRVSPLTYLIDALL---SVGLANASV 1463
Query: 712 APNSNETLGV 721
+SNE L +
Sbjct: 1464 VCSSNELLKI 1473
Score = 102 bits (253), Expect = 1e-20
Identities = 130/577 (22%), Positives = 240/577 (41%), Gaps = 75/577 (12%)
Query: 843 KNQGVTEDR---LELLKGVSGAFRPGVLTALMGVSGAGKTTLMDVLAGIKTSGY---IEG 896
+ G +ED ++LK + G PG L ++G GAG TTL+ ++ + T G+ +
Sbjct: 181 RTHGKSEDNDSGFQILKPMDGCINPGELLVVLGRPGAGCTTLLKSIS-VNTHGFKISPDT 239
Query: 897 NIKVSGYQKNQ--KSFARISGYCEQFDIHSPNVTVYESLLYSAWLRLSPE----VDHAT- 949
I +G+ + + Y + DIH P++TV+++L A L+ VD T
Sbjct: 240 IITYNGFSNKEIKNHYRGEVVYNAESDIHIPHLTVFQTLYTVARLKTPRNRIKGVDRDTF 299
Query: 950 RKMFIEEVMELVELNSLREALVGLPGENGLSTEQRKRLTIAVELVANPSIIFMDEPTSGL 1009
K E M L+ + VG G+S +RKR++IA + D T GL
Sbjct: 300 AKHMTEVAMATYGLSHTADTKVGNDFVRGVSGGERKRVSIAEVSICGSKFQCWDNATRGL 359
Query: 1010 DARAAAIVMRTVRNTVD-TGRTVVCTIHQPSIDIFDSFDELLLLKLGGEQIYAGPIGNQC 1068
D+ A ++ ++ T I+Q S D +D FD++ +L G QI+ GP
Sbjct: 360 DSATALEFIKALKTQATITKSAATVAIYQCSKDAYDLFDKVCVL-YDGYQIFFGP----S 414
Query: 1069 SDLIQYFEAIQGVPTIKDGYNPATWMLEITSAGKEANLK-------------VNFTDVYK 1115
+YF+ + V + A ++ ITS + K +
Sbjct: 415 KQAKKYFQRMGYV--CPERQTTADYLTSITSPSERIKDKDMVKHGIMIPQTAYEMNQYWI 472
Query: 1116 NSELHRR-----NKQLIQELSVPSQSSKDLHFDAQ---------YSQTFLAQCTYCLWKQ 1161
SE +++ NK L + S + K+ H Q Y+ +F Q Y L +
Sbjct: 473 QSEEYKQLQVQVNKHLDTDSSQQREQIKNAHIAKQSKRARPSSPYTVSFFLQVKYILIR- 531
Query: 1162 HLSYWRNTSYTAVRLLFTIMT----GILFGLIFWGVGAKSKKEQDLFNAMGSMYAAVTFI 1217
WR + +++ LFT+++ ++ G +F+ V + + AA+ F
Sbjct: 532 --DIWRIKNDPSIQ-LFTVLSHAAMALILGSMFYEVMLSTTTTTFYYRG-----AAIFFA 583
Query: 1218 GVVNG-ASVQPIVAI--ERTVFYRERAAGMYSAMPYALAQVIIELPHILVQAVVYGIIVY 1274
+ N +S+ I ++ R + + + +Y A A ++P L AV + I Y
Sbjct: 584 ILFNAFSSLLEIFSLYETRPITEKHKTYSLYRPSADAFASTFSDVPTKLATAVTFNIPYY 643
Query: 1275 AMMGFEWTASKVLWNLFFTYFSFLYYTYYGMMTM-----AITPNPHVAGILSTSFYAIWC 1329
++ + A FF YF T + M + +++ A + ++ +
Sbjct: 644 FLINLKRDA-----GAFFFYFLINIITVFAMSHLFRCIGSVSKTLPQAMVPASVLLLAFA 698
Query: 1330 LFSGFIIPLSRIPIWWKWYYWICPVAWTLNGLVTSQY 1366
+++GF IP ++ W KW +I P+++ L+ +++
Sbjct: 699 MYTGFAIPRVQMLGWSKWISYINPLSYLFESLMINEF 735
>CDR4_CANAL (O74676) ABC transporter CDR4
Length = 1490
Score = 420 bits (1079), Expect = e-116
Identities = 326/1280 (25%), Positives = 574/1280 (44%), Gaps = 142/1280 (11%)
Query: 154 ILQNVSGILKPRRMTLLLGPPGSGKTTLLLALAG-ILGKDLKQSGRVTYNGKGLEEFVPQ 212
IL+ + G++KP +T++LG PG+G +T L +A G + + + YN E
Sbjct: 172 ILKPMDGLIKPGELTVVLGRPGAGCSTFLKTIASQTYGYHIDKDSVIRYNSLTPHEIKKH 231
Query: 213 RTS--AYVSQYDNHIGEMTVRETLAFSARCQGVGQNYEMLTELLRKEKESKIEPDPDINA 270
Y ++ +NH ++TV +TL F+A+ +R + + D A
Sbjct: 232 YRGEVVYCAETENHFPQLTVGDTLEFAAK--------------MRTPQNRPLGVSRD--A 275
Query: 271 YMKEAAIEGHQNSVVIDYILKILGLDVCADTMVGDQMIRGISGGEKKRLTTGEMLVGPIK 330
Y + A ++ + GL +T VG+ IRG+SGGE+KR++ E+ +
Sbjct: 276 YARHLAA----------VVMAVYGLSHTRNTKVGNDFIRGVSGGERKRVSIAEITLNNAM 325
Query: 331 VLFMDEISNGLDSSTTFQIINSIKQSIHILNGTALVSLLQPAPETYELFDDIILLTDGQI 390
V D + GLDS+T + I ++K S I++ T LV++ Q + + Y+LFD ++L+ G
Sbjct: 326 VQCWDNSTRGLDSATALEFIRALKASADIVHTTPLVAIYQCSQDAYDLFDKVVLMYQGYQ 385
Query: 391 VYQGPREYVLEFFESTGFKCPERKGVADFLQEVTSRKDQ-----------------WQYW 433
+Y G + ++F G++CP+R+ ADFL +T+ ++ ++YW
Sbjct: 386 IYFGSAKKAKQYFIDMGYECPQRQTTADFLTSLTNPAERIVRQGFEGKVPQTPQEFYEYW 445
Query: 434 AREDEPYNFVTVKDFARAFELFHIGKQLGEELADPFDKSKFHSNVLITKKYGINKKELLR 493
+ E V D L +E +++ ++ Y ++ +R
Sbjct: 446 KKSPEGQQIVADVD----QYLTEHSSAAEKEAIKEAHQARQSDHLKPASPYTVSFFMQVR 501
Query: 494 ACASRELLLMKRNSFVYIFKATQLTYLATLTTTLFLR-----TKMYHSTIEDAQTYMGAL 548
A R +L +K N +++F+ ++ + +++F + YH T AL
Sbjct: 502 YIAHRNILRIKGNPSIHLFQIFGNIGMSFILSSIFYNLPTATSSFYHRT--------AAL 553
Query: 549 FFTVTVAMFNGISELNMTIMKLPIFYKQRDLLFYPSWAYSLPPWILKIPITIIEVAIWEC 608
FF V F+ + E+ I K + Y A + + ++P I +
Sbjct: 554 FFAVLFNAFSCLLEIFSLYEARSIVEKHKKYALYHPAADAFASIVTELPTKFIIAIGFNL 613
Query: 609 ISYYAIGFDPNIGRFFKQSLVVLCINQMASALFRFMAALGRDIVVANTFGTFSLLAVTVL 668
+ Y+ + F G FF L+ S +FR + A + + A T LLA+T+
Sbjct: 614 VYYFMVNFRRTPGNFFFYLLINFSATLAMSHIFRTIGAATKTLQEAMTPAAILLLALTIF 673
Query: 669 GGFVISREDVHKWFLWGYWSSPLMYGQNAIAVNEF------------LGHGWRKVAPNS- 715
GFVI ++H W W + PL Y ++ NEF G + PN
Sbjct: 674 TGFVIPTPNMHGWCRWINYLDPLAYAFESLIANEFHNRDFECSQYVPSGGSYPTAGPNRI 733
Query: 716 ----NETLGVSILKSRGFFPQAYWY-----WIGVGALIGYVFLFNFLFALALHF-LSPFR 765
G + + ++ Y W G +IG++ F + L +
Sbjct: 734 CTPVGSVPGQDFVDGTRYMEMSFDYRNSHKWRNFGIVIGFIVFFFCTYILLCEINKGAMQ 793
Query: 766 KDQAGLSQEKLQERNASTDEEFIQSQQQENSSNTKMDEEVSENKASSSGRKGMVLPFQPL 825
K + L Q++ ++ + + + ++ + + E +++K SG
Sbjct: 794 KGEILLFQQRALKKRKKANNDIESGEIEKVTPEFDNEYENNQDKMLQSGGD--------- 844
Query: 826 SLTFDDITYSVDMPQGMKNQGVTEDRLELLKGVSGAFRPGVLTALMGVSGAGKTTLMDVL 885
+ + D+TY V + +EDR+ +L VSG +PG +TALMG SGAGKTTL++ L
Sbjct: 845 TFFWRDLTYQVKIK--------SEDRV-ILDHVSGWVKPGQVTALMGASGAGKTTLLNAL 895
Query: 886 AGIKTSGYIEGNIKVSGYQKNQKSFARISGYCEQFDIHSPNVTVYESLLYSAWLRLSPEV 945
+ T+G + I++ + SF R GY +Q D+H TV E+L ++A+LR V
Sbjct: 896 SDRLTTGVVTEGIRLVNGRPLDSSFQRSIGYVQQQDLHLETSTVREALEFAAYLRQPKSV 955
Query: 946 DHATRKMFIEEVMELVELNSLREALVGLPGENGLSTEQRKRLTIAVELVANPS-IIFMDE 1004
+ +++ ++ L+E+ +A+VG+ GE GL+ EQRKRL+I VELVA P ++F+DE
Sbjct: 956 SRKEKNEYVDYIIRLLEMEQYADAVVGVSGE-GLNVEQRKRLSIGVELVAKPKLLVFLDE 1014
Query: 1005 PTSGLDARAAAIVMRTVRNTVDTGRTVVCTIHQPSIDIFDSFDELLLLKLGGEQIYAGPI 1064
PTSGLD++ A + + +R D G+ ++CTIHQPS + FD LL L+ GG+ +Y G +
Sbjct: 1015 PTSGLDSQTAWSICKLIRKLADNGQAILCTIHQPSAILLAEFDRLLFLQRGGQTVYFGDL 1074
Query: 1065 GNQCSDLIQYFEAIQGVPTIKDGYNPATWMLEITSAGKEANLKVNFTDVY-KNSELHRRN 1123
G + LI YFE G P NPA WMLE+ A + ++ DV+ K+SE N
Sbjct: 1075 GKNFTTLINYFEK-YGAPKCPPEANPAEWMLEVIGAAPGSKANQDYYDVWLKSSEFQEMN 1133
Query: 1124 KQLIQELSVPSQSSKDLHFDAQYSQTFLAQCTYCLWKQHL--------SYWRNTSYTAVR 1175
+L +L K L D + + A W+Q+L WR SY +
Sbjct: 1134 SEL--DLMSEELVKKPLDDDPDRLKPYAAP----YWEQYLFVTKRVFEQNWRTPSYLYSK 1187
Query: 1176 LLFTIMTGILFGLIFWGVGAKSKKEQDLFNAMGSMYAAVTFIGVVNGASVQ--PIVAIER 1233
L + + + G F+ K ++ L M++ F+ +++ Q P +R
Sbjct: 1188 FLLVVTSSLFNGFSFY------KADRSLQGLQNQMFSVFMFLVILHTLIQQYLPTFVSQR 1241
Query: 1234 TVF-YRERAAGMYSAMPYALAQVIIELPHILVQAVVYGIIVYAMMGFEWTAS-------- 1284
++ RER + +S + + AQV E+P ++ + Y +G A+
Sbjct: 1242 DLYEVRERPSKTFSWITFIAAQVTAEIPWNIICGTLGYFCWYYPVGLYQNATYTNTVHQR 1301
Query: 1285 -KVLWNLFFTYFSFLYYTYYGMMTMAITPNPHVAGILSTSFYAIWCLFSGFIIPLSRIPI 1343
+W F F+Y + + ++ A LS + + F G ++ ++P
Sbjct: 1302 GAFMW--FAIVLFFIYTSTLAQLCISFLEIDDNAANLSVLLFTMCLAFCGVLVTKEQLPG 1359
Query: 1344 WWKWYYWICPVAWTLNGLVT 1363
+W + Y P + ++ +++
Sbjct: 1360 FWVFMYRCSPFTYLVSVMLS 1379
Score = 120 bits (302), Expect = 2e-26
Identities = 129/556 (23%), Positives = 230/556 (41%), Gaps = 41/556 (7%)
Query: 848 TEDRLELLKGVSGAFRPGVLTALMGVSGAGKTTLMDVLAGIKTSGYIEGNIKVSGYQ--- 904
T ++LK + G +PG LT ++G GAG +T + +A +T GY V Y
Sbjct: 166 TGPTFDILKPMDGLIKPGELTVVLGRPGAGCSTFLKTIAS-QTYGYHIDKDSVIRYNSLT 224
Query: 905 --KNQKSFARISGYCEQFDIHSPNVTVYESLLYSAWLR------LSPEVDHATRKMFIEE 956
+ +K + YC + + H P +TV ++L ++A +R L D R +
Sbjct: 225 PHEIKKHYRGEVVYCAETENHFPQLTVGDTLEFAAKMRTPQNRPLGVSRDAYARHL-AAV 283
Query: 957 VMELVELNSLREALVGLPGENGLSTEQRKRLTIAVELVANPSIIFMDEPTSGLDARAAAI 1016
VM + L+ R VG G+S +RKR++IA + N + D T GLD+ A
Sbjct: 284 VMAVYGLSHTRNTKVGNDFIRGVSGGERKRVSIAEITLNNAMVQCWDNSTRGLDSATALE 343
Query: 1017 VMRTVRNTVDTGRTV-VCTIHQPSIDIFDSFDELLLLKLGGEQIYAGPIGNQCSDLIQY- 1074
+R ++ + D T + I+Q S D +D FD+++L+ G QIY G I
Sbjct: 344 FIRALKASADIVHTTPLVAIYQCSQDAYDLFDKVVLM-YQGYQIYFGSAKKAKQYFIDMG 402
Query: 1075 FEAIQGVPT---IKDGYNPATWMLEITSAGKEANLKVNFTDVYKNSELHRR--------- 1122
+E Q T + NPA ++ GK F + +K S ++
Sbjct: 403 YECPQRQTTADFLTSLTNPAERIVRQGFEGKVPQTPQEFYEYWKKSPEGQQIVADVDQYL 462
Query: 1123 -------NKQLIQELSVPSQSSKDLHFDAQYSQTFLAQCTYCLWKQHLSYWRNTSYTAVR 1175
K+ I+E QS L + Y+ +F Q Y + L N S +
Sbjct: 463 TEHSSAAEKEAIKEAHQARQSDH-LKPASPYTVSFFMQVRYIAHRNILRIKGNPSIHLFQ 521
Query: 1176 LLFTIMTGILFGLIFWGVGAKSKKEQDLFNAMGSMYAAVTFIGVVNGASVQPIVAIERTV 1235
+ I + IF+ + + ++ +++ AV F + + R++
Sbjct: 522 IFGNIGMSFILSSIFYNLPTATSS---FYHRTAALFFAVLFNAFSCLLEIFSLYEA-RSI 577
Query: 1236 FYRERAAGMYSAMPYALAQVIIELPHILVQAVVYGIIVYAMMGFEWTASKVLWNLFFTYF 1295
+ + +Y A A ++ ELP + A+ + ++ Y M+ F T + L +
Sbjct: 578 VEKHKKYALYHPAADAFASIVTELPTKFIIAIGFNLVYYFMVNFRRTPGNFFFYLLINFS 637
Query: 1296 SFLYYTYYGMMTMAITPNPHVAGILSTSFYAIWCLFSGFIIPLSRIPIWWKWYYWICPVA 1355
+ L ++ A T A + +F+GF+IP + W +W ++ P+A
Sbjct: 638 ATLAMSHIFRTIGAATKTLQEAMTPAAILLLALTIFTGFVIPTPNMHGWCRWINYLDPLA 697
Query: 1356 WTLNGLVTSQYGHNMD 1371
+ L+ +++ HN D
Sbjct: 698 YAFESLIANEF-HNRD 712
>SNQ2_YEAST (P32568) SNQ2 protein
Length = 1501
Score = 406 bits (1044), Expect = e-112
Identities = 333/1277 (26%), Positives = 587/1277 (45%), Gaps = 131/1277 (10%)
Query: 149 KKQLHILQNVSGILKPRRMTLLLGPPGSGKTTLLLALAGILGKDLKQ-SGRVTYNGKGLE 207
+K I+ NV+ + + M L+LG PG+G ++ L AG + + SG V Y+G E
Sbjct: 170 QKMRQIISNVNALAEAGEMILVLGRPGAGCSSFLKVTAGEIDQFAGGVSGEVAYDGIPQE 229
Query: 208 EFVPQRTS--AYVSQYDNHIGEMTVRETLAFSARCQGVGQNYEMLTELLRKEKESKIEPD 265
E + + + Y + D H +TV++TL F+ C+ T LR SK E
Sbjct: 230 EMMKRYKADVIYNGELDVHFPYLTVKQTLDFAIACK---------TPALRVNNVSKKE-- 278
Query: 266 PDINAYMKEAAIEGHQNSVVIDYILKILGLDVCADTMVGDQMIRGISGGEKKRLTTGEML 325
Y+ D I GL +T VG+ +RG+SGGE+KR++ E L
Sbjct: 279 -----YIASRR----------DLYATIFGLRHTYNTKVGNDFVRGVSGGERKRVSIAEAL 323
Query: 326 VGPIKVLFMDEISNGLDSSTTFQIINSIKQSIHILNGTALVSLLQPAPETYELFDDIILL 385
+ D + GLD+ST + +I+ ++L TA V++ Q + YE FD + +L
Sbjct: 324 AAKGSIYCWDNATRGLDASTALEYAKAIRIMTNLLKSTAFVTIYQASENIYETFDKVTVL 383
Query: 386 TDGQIVYQGPREYVLEFFESTGFKCPERKGVADFLQEVT------------------SRK 427
G+ +Y G +F G+ CP R+ A+FL +T + +
Sbjct: 384 YSGKQIYFGLIHEAKPYFAKMGYLCPPRQATAEFLTALTDPNGFHLIKPGYENKVPRTAE 443
Query: 428 DQWQYWAREDEPYNFVTVKDFARAFELFHIGKQLGEELADPFDKSKFHSNVLITKK---Y 484
+ YW E F +K A++ K E+ + +D+S T+K Y
Sbjct: 444 EFETYWLNSPE---FAQMKKDIAAYK----EKVNTEKTKEVYDESMAQEKSKYTRKKSYY 496
Query: 485 GINKKELLRACASRELLLMKRNSFVYIFKATQLTYLATLTTTLFLRTKMYHSTIEDAQTY 544
++ E ++ C R + N + + +T +LF T S+ A +
Sbjct: 497 TVSYWEQVKLCTQRGFQRIYGNKSYTVINVCSAIIQSFITGSLFYNTP---SSTSGAFSR 553
Query: 545 MGALFFTVTVAMFNGISELNMTIMKLPIFYKQRDLLFYPSWAYSLPPWILKIPITIIEVA 604
G L+F + G++ N++ PI K + Y A ++ + P +I +
Sbjct: 554 GGVLYFALLYYSLMGLA--NISFEHRPILQKHKGYSLYHPSAEAIGSTLASFPFRMIGLT 611
Query: 605 IWECISYYAIGFDPNIGRFFKQSLVVLCINQMASALFRFMAALGRDIVVANTFGTFSLLA 664
+ I ++ G G FF L + ++ + LF ++++ + AN+ +++
Sbjct: 612 CFFIILFFLSGLHRTAGSFFTIYLFLTMCSEAINGLFEMVSSVCDTLSQANSISGILMMS 671
Query: 665 VTVLGGFVISREDVHKWFLWGYWSSPLMYGQNAIAVNEFLGHGWR--------------- 709
+++ ++I +H WF W + P+ Y ++ EF G
Sbjct: 672 ISMYSTYMIQLPSMHPWFKWISYVLPIRYAFESMLNAEFHGRHMDCANTLVPSGGDYDNL 731
Query: 710 ----KVA------PNSNETLGVSILKSRGFFPQAYWY-WIGVGALIGYVFLFNFLFALAL 758
KV P + LG LK++ F Y + W G L ++ + L +
Sbjct: 732 SDDYKVCAFVGSKPGQSYVLGDDYLKNQ--FQYVYKHTWRNFGILWCFLLGYVVLKVIFT 789
Query: 759 HFLSPFRKDQAGLSQEKLQERN-ASTDEEF------IQSQQQENSSNTKMDEEVSENKAS 811
+ P + L +K +R A DEE I +++Q +S ++ ++EV ++ +
Sbjct: 790 EYKRPVKGGGDALIFKKGSKRFIAHADEESPDNVNDIDAKEQFSSESSGANDEVFDDLEA 849
Query: 812 SSGRKGMVLPFQPLSLTFDDITYSVDMPQGMKNQGVTEDRLELLKGVSGAFRPGVLTALM 871
KG+ + + D+ +++ G + LL VSG PG +TALM
Sbjct: 850 ----KGVFI--------WKDVCFTIPYEGGKRM---------LLDNVSGYCIPGTMTALM 888
Query: 872 GVSGAGKTTLMDVLAGIKTSGYIEGNIKVSGYQKNQKSFARISGYCEQFDIHSPNVTVYE 931
G SGAGKTTL++ LA + G I G++ V+G + SF R +GY +Q DIH +TV E
Sbjct: 889 GESGAGKTTLLNTLAQ-RNVGIITGDMLVNG-RPIDASFERRTGYVQQQDIHIAELTVRE 946
Query: 932 SLLYSAWLRLSPEVDHATRKMFIEEVMELVELNSLREALVGLPGENGLSTEQRKRLTIAV 991
SL +SA +R + + + ++E+++ ++ + EALVG G GL+ EQRK+L+I V
Sbjct: 947 SLQFSARMRRPQHLPDSEKMDYVEKIIRVLGMEEYAEALVGEVG-CGLNVEQRKKLSIGV 1005
Query: 992 ELVANPSII-FMDEPTSGLDARAAAIVMRTVRNTVDTGRTVVCTIHQPSIDIFDSFDELL 1050
ELVA P ++ F+DEPTSGLD++++ +++ +R G++++CTIHQPS +F+ FD LL
Sbjct: 1006 ELVAKPDLLLFLDEPTSGLDSQSSWAIIQLLRKLSKAGQSILCTIHQPSATLFEEFDRLL 1065
Query: 1051 LLKLGGEQIYAGPIGNQCSDLIQYFEAIQGVPTIKDGYNPATWMLEITSAGKEANLKVNF 1110
LL+ GG+ +Y G IG + ++ YFE G NPA ++LE AG A++K ++
Sbjct: 1066 LLRKGGQTVYFGDIGKNSATILNYFER-NGARKCDSSENPAEYILEAIGAGATASVKEDW 1124
Query: 1111 TDVYKNSELHRRNKQLIQEL--SVPSQSSKDLHFD--AQYSQTFLAQCTYCLWKQHLSYW 1166
+ + NS + K+ +Q+L + Q +K D ++Y+ ++ Q Y L + S+W
Sbjct: 1125 HEKWLNSVEFEQTKEKVQDLINDLSKQETKSEVGDKPSKYATSYAYQFRYVLIRTSTSFW 1184
Query: 1167 RNTSYTAVRLLFTIMTGILFGLIFWGVGAKSKKEQDLFNAMGSMYAAVTFIGVVNGASVQ 1226
R+ +Y +++ ++ G+ G F+ VG K L NAM + + ++
Sbjct: 1185 RSLNYIMSKMMLMLVGGLYIGFTFFNVG---KSYVGLQNAMFAAFISIILSAPAMNQIQG 1241
Query: 1227 PIVAIERTVFYRERAAGMYSAMPYALAQVIIELPHILVQAVVYGIIVYAMMGFEWTASK- 1285
+A RE + M+ + Q + ELP+ L + ++ + Y + + AS+
Sbjct: 1242 RAIASRELFEVRESQSNMFHWSLVLITQYLSELPYHLFFSTIFFVSSYFPLRIFFEASRS 1301
Query: 1286 VLWNLFFTYFSFLYYTYYGMMTMAITPNPHVAGILSTSFYAIWCLFSGFIIPLSRIPIWW 1345
++ L + LYY G+M + ++PN A ++ + F G P+S +P +W
Sbjct: 1302 AVYFLNYCIMFQLYYVGLGLMILYMSPNLPSANVILGLCLSFMLSFCGVTQPVSLMPGFW 1361
Query: 1346 KWYYWICPVAWTLNGLV 1362
+ + P + + LV
Sbjct: 1362 TFMWKASPYTYFVQNLV 1378
Score = 108 bits (271), Expect = 8e-23
Identities = 94/303 (31%), Positives = 155/303 (51%), Gaps = 57/303 (18%)
Query: 145 IPSPKKQLHILQNVSGILKPRRMTLLLGPPGSGKTTLLLALA----GILGKDLKQSGRVT 200
IP + +L NVSG P MT L+G G+GKTTLL LA GI+ +G +
Sbjct: 862 IPYEGGKRMLLDNVSGYCIPGTMTALMGESGAGKTTLLNTLAQRNVGII------TGDML 915
Query: 201 YNGKGLEEFVPQRTSAYVSQYDNHIGEMTVRETLAFSARCQGVGQNYEMLTELLRKEKES 260
NG+ ++ +RT YV Q D HI E+TVRE+L FSAR +R+ +
Sbjct: 916 VNGRPIDASFERRT-GYVQQQDIHIAELTVRESLQFSAR--------------MRRPQHL 960
Query: 261 KIEPDPDINAYMKEAAIEGHQNSVVIDYILKILGLDVCADTMVGDQMIRGISGGEKKRLT 320
PD + Y ++ I+++LG++ A+ +VG ++ G++ ++K+L+
Sbjct: 961 ---PDSEKMDY--------------VEKIIRVLGMEEYAEALVG-EVGCGLNVEQRKKLS 1002
Query: 321 TG-EMLVGPIKVLFMDEISNGLDSSTTFQIINSIKQSIHILNGTALVSLLQPAPETYELF 379
G E++ P +LF+DE ++GLDS +++ II +++ + + L ++ QP+ +E F
Sbjct: 1003 IGVELVAKPDLLLFLDEPTSGLDSQSSWAIIQLLRK-LSKAGQSILCTIHQPSATLFEEF 1061
Query: 380 DDIILL-TDGQIVYQGP----REYVLEFFESTGF-KCPERKGVADFLQE------VTSRK 427
D ++LL GQ VY G +L +FE G KC + A+++ E S K
Sbjct: 1062 DRLLLLRKGGQTVYFGDIGKNSATILNYFERNGARKCDSSENPAEYILEAIGAGATASVK 1121
Query: 428 DQW 430
+ W
Sbjct: 1122 EDW 1124
>CDR3_CANAL (O42690) Opaque-specific ABC transporter CDR3
Length = 1501
Score = 404 bits (1039), Expect = e-112
Identities = 338/1286 (26%), Positives = 576/1286 (44%), Gaps = 141/1286 (10%)
Query: 154 ILQNVSGILKPRRMTLLLGPPGSGKTTLLLALA-GILGKDLKQSGRVTYNGKGLEEFVPQ 212
IL+ + G++KP +T++LG PG+G +T L +A G + ++Y+G +E
Sbjct: 160 ILKPMEGLIKPGEVTVVLGRPGAGCSTFLKTIACRTEGFHVADGSVISYDGITQDEIRNH 219
Query: 213 RTS--AYVSQYDNHIGEMTVRETLAFSARCQGVGQNYEMLTELLRKEKESKIEPDPDINA 270
Y ++ + H +TV ETL F+A + QN M + R+E
Sbjct: 220 LRGEVVYCAETETHFPNLTVGETLEFAALMK-TPQNRPM--GVSREE------------- 263
Query: 271 YMKEAAIEGHQNSVVIDYILKILGLDVCADTMVGDQMIRGISGGEKKRLTTGEMLVGPIK 330
Y K V+D ++ GL +T VG+ IRGISGGE+KRL+ E+ +
Sbjct: 264 YAKH----------VVDVVMATYGLSHTKNTKVGNDFIRGISGGERKRLSIAEVTLVQAS 313
Query: 331 VLFMDEISNGLDSSTTFQIINSIKQSIHILNGTALVSLLQPAPETYELFDDIILLTDGQI 390
+ D + GLD++T + I+S+K S ILN T L+++ Q + Y+LFD +I++ +G
Sbjct: 314 IQCWDNSTRGLDAATALEFISSLKTSASILNDTPLIAIYQCSQNAYDLFDKVIVMYEGYQ 373
Query: 391 VYQGPREYVLEFFESTGFKCPERKGVADFLQEVTSR-----------------KDQWQYW 433
++ G + +F+ GF C +R+ DFL +TS K+ ++YW
Sbjct: 374 IFFGSSQRAAAYFKKMGFVCQDRQTTPDFLTSITSPAERIIKPGYERLVPRTPKEFYRYW 433
Query: 434 AREDEPYNFVTVKDFARAFELFHIGKQLGEELADPFDKSK--FHSNVLITKKYGINKKEL 491
R E R L I + L + +D+ + F +N K+ NK
Sbjct: 434 RRSPE-----------RQALLEEIDEYLDN--CENYDQKQKIFEANNAKKAKHTYNKSSY 480
Query: 492 LRACASRELLLMKRNSFVYIFKATQLTYLAT----LTTTLFLRTKMYHSTIEDAQTYM-- 545
+ + +MKR + + + L+T + L L + Y+ + Y
Sbjct: 481 TVSLPMQVRYIMKR--YWDRMRGDIIVPLSTVAGNIAMALILSSVFYNLQPNSSSFYYRT 538
Query: 546 GALFFTVTVAMFNGISELNMTIMKLPIFYKQRDLLFYPSWAYSLPPWILKIPITIIEVAI 605
+++ + ++ + E+ I K R+ YP A ++ I P+ ++ +
Sbjct: 539 SVMYYALLFNAYSSVLEIYNMYEGRAIVQKHREYALYPPMADAIGSIISDFPLKVVCSVL 598
Query: 606 WECISYYAIGFDPNIGRFFKQSLVVLCINQMASALFRFMAALGRDIVVANTFGTFSLLAV 665
+ I Y+ + F G FF L+ C S LFR + A + A T + L A+
Sbjct: 599 FNLILYFMVNFKREPGAFFFYLLISFCSTLFMSHLFRTIGAFTNSLAEAMTPSSLLLFAL 658
Query: 666 TVLGGFVISREDVHKWFLWGYWSSPLMYGQNAIAVNEFLGHGW--RKVAPNS-------N 716
+ GF I + W W W +PL Y A+ NEF G + + P+ N
Sbjct: 659 STFSGFAIPVTYMLGWCKWIRWVNPLAYAYEALISNEFHGRVFDCSNIVPSGFGYPKTGN 718
Query: 717 ETLGVSILKSRGFFPQ--------AYWY-----WIGVGALIGYVFLFNFLFALALHFLSP 763
+ SI G F A+ Y W G L+ ++ FLF + F+
Sbjct: 719 SVVCASIGALPGEFKVDGDLYLKLAFDYSYSNVWRNFGVLMAFII---FLFGTTIFFVQT 775
Query: 764 FRKDQAGLSQEKLQERNASTDEEFIQSQQQENSSNTKMD----EEVSENKASSSGRKGMV 819
+ + + +N + + ++ +D E+S+ RK
Sbjct: 776 NKSSISKGETLVFRRKNIRKMRKMEEDEEAYMDGMAPLDFSGSTEISDYSYDYMDRK--- 832
Query: 820 LPFQPLSLTFDDITYSVDMPQGMKNQGVTEDRLELLKGVSGAFRPGVLTALMGVSGAGKT 879
L + ++TY+V + +E+R+ +L + G +PG +TALMG SGAGKT
Sbjct: 833 LLDTSNIFHWRNLTYTVKIK--------SEERV-ILNNIDGWVKPGEVTALMGASGAGKT 883
Query: 880 TLMDVLAGIKTSGYIEGNIKVSGYQKNQKSFARISGYCEQFDIHSPNVTVYESLLYSAWL 939
TL++ L+ T+G I ++ + SF R GY +Q D+H TV E+L +SA L
Sbjct: 884 TLLNALSERLTTGVITSGTRMVNGGELDSSFQRSIGYVQQQDLHLETSTVREALKFSARL 943
Query: 940 RLSPEVDHATRKMFIEEVMELVELNSLREALVGLPGENGLSTEQRKRLTIAVELVANPS- 998
R V A + ++E++++L+E+ + +A+VG+PGE GL+ EQRKRLTIAVELVA P
Sbjct: 944 RQPNSVSIAEKDSYVEKIIDLLEMRTYVDAIVGVPGE-GLNVEQRKRLTIAVELVARPKL 1002
Query: 999 IIFMDEPTSGLDARAAAIVMRTVRNTVDTGRTVVCTIHQPSIDIFDSFDELLLLKLGGEQ 1058
++F+DEPTSGLD++ A + + +R + G+ ++CTIHQPS + + FD LLLL+ GE
Sbjct: 1003 LVFLDEPTSGLDSQTAWSICKLIRKLANHGQAILCTIHQPSAILLEEFDRLLLLQ-KGET 1061
Query: 1059 IYAGPIGNQCSDLIQYFEAIQGVPTIKDGYNPATWMLEITSAGKEANLKVNFTDVYKNS- 1117
+Y G G C LI+YFE G NPA WML + A ++ + ++NS
Sbjct: 1062 VYFGEFGANCHTLIEYFER-NGASKCPQHANPAEWMLGVIGAAPGTQANQDYFETWRNSP 1120
Query: 1118 -------ELHRRNKQLIQELSVPSQSSKDLHFDAQYSQTFLAQCTYCLWKQHLSYWRNTS 1170
ELHR ++E+ + K+ + Y+ +F Q + + + YWR S
Sbjct: 1121 EYRAVQNELHR-----LEEMPGLASGEKEPDTNQAYAASFWKQYIFVVHRLFQQYWRTPS 1175
Query: 1171 YTAVRLLFTIMTGILFGLIFWGVGAKSKKEQDLFNAMGSMYAAVTFIGVVNGASVQPIVA 1230
Y + ++ + G ++ Q L N M S+++ + + V P+
Sbjct: 1176 YIYSKFAMAVLCSLFNGFTYY---KSQNSMQGLKNQMLSIFSMFVVLTTLAQQYV-PLFV 1231
Query: 1231 IERTVF-YRERAAGMYSAMPYALAQVIIELPHILVQAVV--------YGIIVYAMMGFEW 1281
+R ++ RER + +S + + AQ+ E+P+ ++ A + G+ A+
Sbjct: 1232 TQRDLYEARERPSKTFSWLAFIAAQITAEIPYQVLAATISFFSWYYPVGLYRNAVYSGAV 1291
Query: 1282 TASKVLWNLFFTYFSFLYYTYYGMMTMAITPNPHVAGILSTSFYAIWCLFSGFIIPLSRI 1341
T VL L T F+Y + ++ A + I +F G I +
Sbjct: 1292 THRGVLMWLIMT-LMFIYSSTLAQFCISWNQLADYAANWISLLLTISMIFCGVIATKDSM 1350
Query: 1342 PIWWKWYYWICPVAWTLNGLVTSQYG 1367
P +W + Y P+ + + +++ G
Sbjct: 1351 PKFWVFLYRCTPLTYLTSAMMSIGLG 1376
Score = 121 bits (304), Expect = 1e-26
Identities = 129/546 (23%), Positives = 234/546 (42%), Gaps = 40/546 (7%)
Query: 853 ELLKGVSGAFRPGVLTALMGVSGAGKTTLMDVLAGIKTSGYIEGNIKVSGYQKNQKSFAR 912
++LK + G +PG +T ++G GAG +T + +A +T G+ + V Y + R
Sbjct: 159 DILKPMEGLIKPGEVTVVLGRPGAGCSTFLKTIA-CRTEGFHVADGSVISYDGITQDEIR 217
Query: 913 --ISG---YCEQFDIHSPNVTVYESLLYSAWLRLSPEVDHATR-----KMFIEEVMELVE 962
+ G YC + + H PN+TV E+L ++A ++ K ++ VM
Sbjct: 218 NHLRGEVVYCAETETHFPNLTVGETLEFAALMKTPQNRPMGVSREEYAKHVVDVVMATYG 277
Query: 963 LNSLREALVGLPGENGLSTEQRKRLTIAVELVANPSIIFMDEPTSGLDARAAAIVMRTVR 1022
L+ + VG G+S +RKRL+IA + SI D T GLDA A + +++
Sbjct: 278 LSHTKNTKVGNDFIRGISGGERKRLSIAEVTLVQASIQCWDNSTRGLDAATALEFISSLK 337
Query: 1023 NTVDT-GRTVVCTIHQPSIDIFDSFDELLLLKLGGEQIYAGP----------IGNQCSDL 1071
+ T + I+Q S + +D FD+++++ G QI+ G +G C D
Sbjct: 338 TSASILNDTPLIAIYQCSQNAYDLFDKVIVM-YEGYQIFFGSSQRAAAYFKKMGFVCQDR 396
Query: 1072 IQYFEAIQGVPT-----IKDGYN---PAT--WMLEITSAGKEANLKVNFTDVYKNSELHR 1121
+ + + + IK GY P T E + D Y ++ +
Sbjct: 397 QTTPDFLTSITSPAERIIKPGYERLVPRTPKEFYRYWRRSPERQALLEEIDEYLDNCENY 456
Query: 1122 RNKQLIQELSVPSQSSKDLHFDAQYSQTFLAQCTYCLWKQHLSYWRNTSYTAVRLLFTIM 1181
KQ I E + ++ +K + + Y+ + Q Y + + YW + L T+
Sbjct: 457 DQKQKIFEAN-NAKKAKHTYNKSSYTVSLPMQVRYIMKR----YWDRMRGDIIVPLSTVA 511
Query: 1182 TGILFGLIFWGVGAKSKKEQDLFNAMGS-MYAAVTFIGVVNGASVQPIVAIERTVFYRER 1240
I LI V + F S MY A+ F + + + R + + R
Sbjct: 512 GNIAMALILSSVFYNLQPNSSSFYYRTSVMYYALLFNAYSSVLEIYNMYE-GRAIVQKHR 570
Query: 1241 AAGMYSAMPYALAQVIIELPHILVQAVVYGIIVYAMMGFEWTASKVLWNLFFTYFSFLYY 1300
+Y M A+ +I + P +V +V++ +I+Y M+ F+ + L ++ S L+
Sbjct: 571 EYALYPPMADAIGSIISDFPLKVVCSVLFNLILYFMVNFKREPGAFFFYLLISFCSTLFM 630
Query: 1301 TYYGMMTMAITPNPHVAGILSTSFYAIWCLFSGFIIPLSRIPIWWKWYYWICPVAWTLNG 1360
++ A T + A S+ FSGF IP++ + W KW W+ P+A+
Sbjct: 631 SHLFRTIGAFTNSLAEAMTPSSLLLFALSTFSGFAIPVTYMLGWCKWIRWVNPLAYAYEA 690
Query: 1361 LVTSQY 1366
L+++++
Sbjct: 691 LISNEF 696
>PDRC_YEAST (Q02785) ATP-dependent permease PDR12
Length = 1511
Score = 402 bits (1033), Expect = e-111
Identities = 334/1312 (25%), Positives = 587/1312 (44%), Gaps = 149/1312 (11%)
Query: 153 HILQNVSGILKPRRMTLLLGPPGSGKTTLLLALAGILGKDLKQSGRVTYNGKGLEEFVPQ 212
+I+QN +G+++ M ++G PG+G +T L L+G + + G +Y+G E + +
Sbjct: 162 NIIQNCTGVVESGEMLFVVGRPGAGCSTFLKCLSGETSELVDVQGEFSYDGLDQSEMMSK 221
Query: 213 RTS--AYVSQYDNHIGEMTVRETLAFSARCQGVGQNYEMLTELLRKEKESKIEPDPDINA 270
Y + D H ++TV+ET+ F+ +C+ + +T RK+ I
Sbjct: 222 YKGYVIYCPELDFHFPKITVKETIDFALKCKTPRVRIDKMT---RKQYVDNIR------- 271
Query: 271 YMKEAAIEGHQNSVVIDYILKILGLDVCADTMVGDQMIRGISGGEKKRLTTGEMLVGPIK 330
D + GL T VG+ +RG+SGGE+KR++ E
Sbjct: 272 ----------------DMWCTVFGLRHTYATKVGNDFVRGVSGGERKRVSLVEAQAMNAS 315
Query: 331 VLFMDEISNGLDSSTTFQIINSIKQSIHILNGTALVSLLQPAPETYELFDDIILLTDGQI 390
+ D + GLD+ST + +I+ + +++N +A+V++ Q YELFD +L +G+
Sbjct: 316 IYSWDNATRGLDASTALEFAQAIRTATNMVNNSAIVAIYQAGENIYELFDKTTVLYNGRQ 375
Query: 391 VYQGPREYVLEFFESTGFKCPERKGVADFLQEVT------------SRKDQWQYWAREDE 438
+Y GP + + +F+ G+ P R A+FL VT +D+ + E E
Sbjct: 376 IYFGPADKAVGYFQRMGWVKPNRMTSAEFLTSVTVDFENRTLDIKPGYEDKVPKSSSEFE 435
Query: 439 PY--NFVTVKDFARAFELFHIGKQLGE--ELADPFDKSKFHSNVLITKKYGINKKELLRA 494
Y N ++ R ++ + + E + D K + +Y +N +
Sbjct: 436 EYWLNSEDYQELLRTYDDYQSRHPVNETRDRLDVAKKQRLQQGQRENSQYVVNYWTQVYY 495
Query: 495 CASRELLLMKRNSFVYIFKATQLTYLATLTTTLFLRTKMYH-------STIEDAQTYMGA 547
C R +K +S YL++ + M+H ST A + G
Sbjct: 496 CMIRGFQRVKGDS------TYTKVYLSSFLIKALIIGSMFHKIDDKSQSTTAGAYSRGGM 549
Query: 548 LFFTVTVAMFNGISELNMTIMKLPIFYKQRDLLFYPSWAYSLPPWILKIPITIIEVAIWE 607
LF+ + A ++E+ + P+ K + Y A SL I + P + + I
Sbjct: 550 LFYVLLFASVTSLAEIGNSFSSRPVIVKHKSYSMYHLSAESLQEIITEFPTKFVAIVILC 609
Query: 608 CISYYAIGFDPNIGRFFKQSLVVLCINQMASALFRFMAALGRDIVVANTFGTFSLLAVTV 667
I+Y+ G FF+ L +L + Q S +F+F+A + + V A+ G +L + V
Sbjct: 610 LITYWIPFMKYEAGAFFQYILYLLTVQQCTSFIFKFVATMSKSGVDAHAVGGLWVLMLCV 669
Query: 668 LGGFVISREDVHKWFLWGYWSSPLMYGQNAIAVNEF------------LGHGWR------ 709
GFV+ ++H W W ++ +PL Y ++ EF G G+
Sbjct: 670 YAGFVLPIGEMHHWIRWLHFINPLTYAFESLVSTEFHHREMLCSALVPSGPGYEGISIAN 729
Query: 710 KVAPNSNETLGVSILKSRGFFPQAYWY-----WIGVGALIGYVFLFNFLFALALHFLSPF 764
+V + G + + Y + W G I + F + + +L P
Sbjct: 730 QVCDAAGAVKGNLYVSGDSYILHQYHFAYKHAWRNWGVNIVWTFGYIVFNVILSEYLKPV 789
Query: 765 ----------RKDQAGLSQEKLQERNASTDEEFIQSQQQENSSNTKMDEEVSENKASSSG 814
R L E R AS +E + N N +++ ++E
Sbjct: 790 EGGGDLLLYKRGHMPELGTENADARTASREE----MMEALNGPNVDLEKVIAEKDV---- 841
Query: 815 RKGMVLPFQPLSLTFDDITYSVDMPQGMKNQGVTEDRLELLKGVSGAFRPGVLTALMGVS 874
T++ + Y++ G T +LL V G +PG +TALMG S
Sbjct: 842 ------------FTWNHLDYTIPY------DGATR---KLLSDVFGYVKPGKMTALMGES 880
Query: 875 GAGKTTLMDVLAGIKTSGYIEGNIKVSGYQKNQKSFARISGYCEQFDIHSPNVTVYESLL 934
GAGKTTL++VLA G I G++ V+ + SF R GY Q D H ++V ESL
Sbjct: 881 GAGKTTLLNVLAQRINMGVITGDMLVNA-KPLPASFNRSCGYVAQADNHMAELSVRESLR 939
Query: 935 YSAWLRLSPEVDHATRKMFIEEVMELVELNSLREALVGLPGENGLSTEQRKRLTIAVELV 994
++A LR V + ++E+++ L+ + + EALVG G GL+ EQRK+L+I VELV
Sbjct: 940 FAAELRQQSSVPLEEKYEYVEKIITLLGMQNYAEALVGKTGR-GLNVEQRKKLSIGVELV 998
Query: 995 ANPSII-FMDEPTSGLDARAAAIVMRTVRNTVDTGRTVVCTIHQPSIDIFDSFDELLLLK 1053
A PS++ F+DEPTSGLD+++A +++ +R D+G++++CTIHQPS +F+ FD LLLLK
Sbjct: 999 AKPSLLLFLDEPTSGLDSQSAWSIVQFMRALADSGQSILCTIHQPSATLFEQFDRLLLLK 1058
Query: 1054 LGGEQIYAGPIGNQCSDLIQYFEAIQGVPTIKDGY--NPATWMLEITSAGKEANLKVNFT 1111
GG+ +Y G IG L++YFE G +K G NPA ++L AG A++ ++
Sbjct: 1059 KGGKMVYFGDIGPNSETLLKYFERQSG---MKCGVSENPAEYILNCIGAGATASVNSDWH 1115
Query: 1112 DVYKNSELHRRNKQLIQEL--SVPSQS-SKDLHFDAQYSQTFLAQCTYCLWKQHLSYWRN 1168
D++ S + ++EL ++P ++ + D +++ +++ Q L + L +WR+
Sbjct: 1116 DLWLASPECAAARAEVEELHRTLPGRAVNDDPELATRFAASYMTQIKCVLRRTALQFWRS 1175
Query: 1169 TSYTAVRLLFTIMTGILFGLIFWGVGAKSKKEQDLFNAMGSMYAAVTFIGVVNGASVQPI 1228
Y + + + GL + GV + F+++ + + ++N V
Sbjct: 1176 PVYIRAKFFECVACALFVGLSYVGVNHSVGGAIEAFSSI--FMLLLIALAMINQLHV--- 1230
Query: 1229 VAIERTVFY--RERAAGMYSAMPYALAQVIIELPHILVQAVVYGIIVYAMMGFEWTASKV 1286
A + Y RE A+ + L +E + + I Y F AS
Sbjct: 1231 FAYDSRELYEVREAASNTFHWSVLLLCHAAVENFWSTLCQFMCFICYYWPAQFSGRASHA 1290
Query: 1287 LWNLFFTYFSF-LYYTYYGMMTMAITPNPHVAGILSTSFYAIWCLFSGFIIPLSRIPIWW 1345
+ FF F LY+ YG+ + ++P+ A +++++ +A LF G + P ++P +W
Sbjct: 1291 GFFFFFYVLIFPLYFVTYGLWILYMSPDVPSASMINSNLFAAMLLFCGILQPREKMPAFW 1350
Query: 1346 -KWYYWICPVAWTLNGLVT----------SQYGHNMDTLDNGQSVEEFVRNY 1386
+ Y + P + + LVT + + +N+ +G++ EF+ Y
Sbjct: 1351 RRLMYNVSPFTYVVQALVTPLVHNKKVVCNPHEYNIMDPPSGKTCGEFLSTY 1402
Score = 103 bits (257), Expect = 3e-21
Identities = 83/283 (29%), Positives = 148/283 (51%), Gaps = 42/283 (14%)
Query: 145 IPSPKKQLHILQNVSGILKPRRMTLLLGPPGSGKTTLLLALAGILGKDLKQSGRVTYNGK 204
IP +L +V G +KP +MT L+G G+GKTTLL LA + + +G + N K
Sbjct: 851 IPYDGATRKLLSDVFGYVKPGKMTALMGESGAGKTTLLNVLAQRINMGV-ITGDMLVNAK 909
Query: 205 GLEEFVPQRTSAYVSQYDNHIGEMTVRETLAFSARCQGVGQNYEMLTELLRKEKESKIEP 264
L R+ YV+Q DNH+ E++VRE+L F+A LR++ +E
Sbjct: 910 PLPASF-NRSCGYVAQADNHMAELSVRESLRFAAE--------------LRQQSSVPLE- 953
Query: 265 DPDINAYMKEAAIEGHQNSVVIDYILKILGLDVCADTMVGDQMIRGISGGEKKRLTTG-E 323
+ ++ I+ +LG+ A+ +VG + RG++ ++K+L+ G E
Sbjct: 954 ----------------EKYEYVEKIITLLGMQNYAEALVG-KTGRGLNVEQRKKLSIGVE 996
Query: 324 MLVGPIKVLFMDEISNGLDSSTTFQIINSIKQSIHILNGTALVSLLQPAPETYELFDDII 383
++ P +LF+DE ++GLDS + + I+ ++ ++ + L ++ QP+ +E FD ++
Sbjct: 997 LVAKPSLLLFLDEPTSGLDSQSAWSIVQFMR-ALADSGQSILCTIHQPSATLFEQFDRLL 1055
Query: 384 LL-TDGQIVYQGP----REYVLEFFE-STGFKCPERKGVADFL 420
LL G++VY G E +L++FE +G KC + A+++
Sbjct: 1056 LLKKGGKMVYFGDIGPNSETLLKYFERQSGMKCGVSENPAEYI 1098
>AUS1_YEAST (Q08409) ATP-dependent permease AUS1
Length = 1394
Score = 309 bits (791), Expect = 4e-83
Identities = 307/1347 (22%), Positives = 562/1347 (40%), Gaps = 180/1347 (13%)
Query: 145 IPSPKKQLHILQNVSGILKPRRMTLLLGPPGSGKTTLLLALAGILGKDLKQSGRVTYNGK 204
+P+P QL+ +++ + M L+LG P S T G G + +
Sbjct: 42 MPNPANQLN---DITFQAEAGEMVLVLGYPTS--TLFKTLFHGKTSLSYSPPGSIKFKNN 96
Query: 205 GLEEFVPQ--RTSAYVSQYDNHIGEMTVRETLAFSARCQ---GVGQNYEMLTELLRKEKE 259
+ F + Y ++ D H +TV +T+ F+ C+ G+ ++ ELLR+
Sbjct: 97 EFKSFSEKCPHQIIYNNEQDVHFPFLTVEQTIDFALSCKFDIPKGERDQIRNELLRE--- 153
Query: 260 SKIEPDPDINAYMKEAAIEGHQNSVVIDYILKILGLDVCADTMVGDQMIRGISGGEKKRL 319
GL T+VG+ RG+SGGE+KR+
Sbjct: 154 ---------------------------------FGLSHVLKTIVGNDFFRGVSGGERKRI 180
Query: 320 TTGEMLVGPIKVLFMDEISNGLDSSTTFQIINSIKQSIHILNGTALVSLLQPAPETYELF 379
+ E + V D + GLDS+T + +++ LV + Q + + + F
Sbjct: 181 SIIETFIANGSVYLWDNSTKGLDSATALDFLEILRKMAKATRSVNLVRISQASDKIVDKF 240
Query: 380 DDIILLTDGQIVYQGPREYVLEFFEST-GFKCPERKGVADFLQEVTSRKDQWQYWAREDE 438
D I++L+D ++ G + L +F T G + + ++L + + + + +
Sbjct: 241 DKILMLSDSYQLFYGTVDECLTYFRDTLGIEKDPNDCIIEYLTSILNFQFKNKNLGNLSN 300
Query: 439 PYNFVTVKDFARAFELFHIGKQLGEELADPFDKSKFHSNVL------------------- 479
+ +K + +L D + S ++ N+
Sbjct: 301 SSSASVLKTATGEVTKYTYNSDF--DLYDQWKHSSYYRNIKQQIQGSSIDDSIKEVDPSD 358
Query: 480 ITKKYGINKKELLRACASRELLLMKRNSFVYIFKATQLTYLATLTTTLFLRTKMYHSTIE 539
++ + I K+ L C R +R+ + Q +++ + +L + + Y +
Sbjct: 359 VSPIFNIPLKKQLLFCTKRAF---QRSLGDKAYMTAQ--FISVVIQSLVIGSLFYEIPLT 413
Query: 540 DAQTYM-GAL-FFTVTVAMFNGISELNMTIMKLPIFYKQRDLLFYPSWAYSLPPWILKIP 597
+Y G+L FF++ F ++++ + + P+ KQ L FY +W +L +
Sbjct: 414 TIGSYSRGSLTFFSILFFTFLSLADMPIAFQRQPVVKKQSQLHFYTNWVETLSTTVFDYC 473
Query: 598 ITIIEVAIWECISYYAIGFDPNIGRFFKQSLVVLCINQMASALFRFMAALGRDIVVANTF 657
+ V ++ I Y+ RFF L + N +LF + I VAN F
Sbjct: 474 FKLCLVIVFSIILYFLAHLQYKAARFFIFLLFLSFYNFCMVSLFALTTLVAPTISVANLF 533
Query: 658 GTFSLLAVTVLGGFVISREDVHKWFLWGYWSSPLMYGQNAIAVNEFL------------- 704
LLA+ + +VI +++H WF+W + +P MY AI NE
Sbjct: 534 AGILLLAIAMYASYVIYLKNMHPWFVWIAYLNPAMYAMEAILSNELYNLKLDCSETIVPR 593
Query: 705 GHGWRKVAPNSNE-------TLGVSILKSRGFFPQAYWY-----WIGVGALIGYVFLFNF 752
G + V P S++ TLG ++ R + Q Y W G +IG++ F
Sbjct: 594 GPTYNDV-PFSHKACAWQGATLGNDYVRGRDYLKQGLSYTYHHVWRNFGIIIGFLVFFIA 652
Query: 753 LFALALHFLSP-FRKDQAG------------LSQEKLQERNASTDEEFIQSQQQENSSNT 799
A ++ P F KD+ L++++ +A D +++ + + S++
Sbjct: 653 CTLFASQYIKPYFNKDEIERNNSRLTRWLPFLNKKRGTRSSARNDSKYVGIPKSHSVSSS 712
Query: 800 KMDEEVSENKASSSGRKGMVLPF--QPLSLTFDDITYSVDMPQGMKNQGVTEDRLELLKG 857
+ S S ++ + + QP++ T + + + KN T +L+
Sbjct: 713 SSSLSAVPYQISPSNKEMALNDYNEQPITETVETQKHII----SWKNINYTVGTKKLINN 768
Query: 858 VSGAFRPGVLTALMGVSGAGKTTLMDVLAGIKTSGYIEGNIKVSGYQ-KNQKSFARISGY 916
SG G LTALMG SGAGKTTL++VL+ +G + G I + G+ ++ +F R G+
Sbjct: 769 ASGFISSG-LTALMGESGAGKTTLLNVLSQRVETGVVSGEILIDGHPLTDEDAFKRSIGF 827
Query: 917 CEQFDIHSPNVTVYESLLYSAWLRLSPEVDHATRKMFIEEVMELVELNSLREALVGLPGE 976
+Q D+H ++V ESL S LR + + +++ V L++L S + LV
Sbjct: 828 VQQQDLHLDLLSVKESLEISCLLRGDGD------RAYLDTVSNLLKLPS--DILVA---- 875
Query: 977 NGLSTEQRKRLTIAVELVANPS-IIFMDEPTSGLDARAAAIVMRTVRNTVDTGRTVVCTI 1035
L+ QRK L+I VELV PS ++F+DEPTSGLDA AA +++ ++ G+ + CTI
Sbjct: 876 -DLNPTQRKLLSIGVELVTKPSLLLFLDEPTSGLDAEAALTIVKFLKQLSLQGQAIFCTI 934
Query: 1036 HQPSIDIFDSFDELLLLKLGGEQIYAGPIGNQCSDLIQYFEAIQGVPTIKDGYNPATWML 1095
HQPS + FD + LLK GGE ++ GP+ + C + + + K+ NPA +++
Sbjct: 935 HQPSKSVISHFDNIFLLKRGGECVFFGPMDDACGYFMSHDNTL---VYDKEHDNPADFVI 991
Query: 1096 EI-----TSAGKEA--------NLKVNFTDVYKNSELHRRNKQLIQELSVPSQSSKDLHF 1142
+ +SAGK+ ++++ ++++S + K+ L +++S +
Sbjct: 992 DAVGNSNSSAGKDTAEEALTLNKEAIDWSALWESSVEKKLVKKETARLEDDARASGVDYT 1051
Query: 1143 DAQYSQ-TFLAQCTYCLWKQHLSYWRNTSYTAVRLLFTIMTGILFGLIFWGVGAKSKKEQ 1201
+ + Q ++L Q +Q++ R+ +Y + G+ G FW + Q
Sbjct: 1052 TSLWKQPSYLQQLALITRRQYICTKRDMTYVMAKYCLNGGAGLFIGFSFWHIKHNIIGLQ 1111
Query: 1202 D-LFNAMGSMYAAVTFIGVVNGASVQPIVAIERTVFYRERAAGMYSAMPYALAQVIIELP 1260
D +F ++ + I + +++ + RE + Y L+Q IIELP
Sbjct: 1112 DSIFFCFMALCVSSPLINQIQDKALK----TKEVYVAREARSNTYHWTVLLLSQSIIELP 1167
Query: 1261 HILVQAVVYGIIVYAMMGFE---WTASKVLWNLFFTYFSF-LYYTYYGMMTMAITPNPHV 1316
L + ++ + + GF W+A F Y F YY+ G+ + PN
Sbjct: 1168 LALTSSTLFFVCAFFSCGFNNAGWSAGV----FFLNYMLFAAYYSTLGLWLIYTAPNLQT 1223
Query: 1317 AGILSTSFYAIWCLFSGFIIPLSRIPIWWKWYYWICPVAWTLNGLVTSQY---------- 1366
A + Y+ F G + P S P +WK+ Y + P + + V+
Sbjct: 1224 AAVFVAFIYSFTASFCGVMQPYSLFPTFWKFMYRVSPYTYFVETFVSILLHNWEIKCDMS 1283
Query: 1367 ----GHNMDTLDNGQSVEEFVRNYFGF 1389
G + GQ +E F+ Y G+
Sbjct: 1284 EMVPGQPLTGQSCGQFMEAFIEEYGGY 1310
>PDRB_YEAST (P40550) ATP-dependent permease PDR11
Length = 1410
Score = 301 bits (770), Expect = 1e-80
Identities = 304/1267 (23%), Positives = 508/1267 (39%), Gaps = 161/1267 (12%)
Query: 191 KDLKQS--GRVTYNGKGLEEFVPQ--RTSAYVSQYDNHIGEMTVRETLAFSARCQGVGQN 246
K LK S G + + ++F + Y ++ D H +TV +T+ F+ C+
Sbjct: 80 KHLKYSPEGSIRFKDNEYKQFASKCPHQIIYNNEQDIHFPYLTVEQTIDFALSCK----- 134
Query: 247 YEMLTELLRKEKESKIEPDPDINAYMKEAAIEGHQNSVVIDYILKILGLDVCADTMVGDQ 306
K+ +IE + D +LK GL T VG+
Sbjct: 135 -------FHIPKQERIE---------------------MRDELLKEFGLSHVKKTYVGND 166
Query: 307 MIRGISGGEKKRLTTGEMLVGPIKVLFMDEISNGLDSSTTFQIINSIKQSIHILNGTALV 366
+RG+SGGE+KR++ E + V D + GLDS+T + ++ ++ V
Sbjct: 167 YVRGVSGGERKRISIIETFIANGSVYLWDNSTKGLDSATALEFLSITQKMAKATRSVNFV 226
Query: 367 SLLQPAPETYELFDDIILLTDGQIVYQGPREYVLEFFEST-GFKCPERKGVADFLQEVTS 425
+ Q + + FD I++L D V+ G E L F T K + ++L + +
Sbjct: 227 KISQASDKIVSKFDKILMLGDSFQVFYGTMEECLTHFHDTLQIKKNPNDCIIEYLTSILN 286
Query: 426 RK-----------DQWQYWAREDEPYNFVTVKDFARAF---ELFHIGKQLGEELADPFDK 471
K D + E++ N D + + K + + +
Sbjct: 287 FKFKETSNSIVGLDTPSVVSEENQALNINNETDLHTLWIQSPYYKHWKAITSKTVQECTR 346
Query: 472 SKFHSNVLITKKYGINKKELLRACASR--ELLLMKRNSFVYIFKATQLTYLATLTTTLFL 529
+ + I+ + I K L+ C R E ++ RN + F + + L + +
Sbjct: 347 KDVNPDD-ISPIFSIPLKTQLKTCTVRAFERIIGDRNYLISQFVSVVVQSLVIGSLFYNI 405
Query: 530 RTKMYHSTIEDAQTYMGALFFTVTVAMFNGISELNMTIMKLPIFYKQRDLLFYPSWAYSL 589
S + T+ LFFT F ++++ + + P+ K L FY +W +L
Sbjct: 406 PLTTIGSFSRGSLTFFSILFFT-----FLSLADMPASFQRQPVVRKHVQLHFYYNWVETL 460
Query: 590 PPWILKIPITIIEVAIWECISYYAIGFDPNIGRFFKQSLVVLCINQMASALFRFMAALGR 649
I V I+ I Y+ N RFF L + N +LF A +
Sbjct: 461 ATNFFDCCSKFILVVIFTIILYFLAHLQYNAARFFIFLLFLSVYNFCMVSLFALTALIAP 520
Query: 650 DIVVANTFGTFSLLAVTVLGGFVISREDVHKWFLWGYWSSPLMYGQNAIAVNEFL----- 704
+ +AN LLA+ + +VI +D+H WF+W + +P M+ AI NE
Sbjct: 521 TLSMANLLAGILLLAIAMYASYVIYMKDMHPWFIWIAYLNPAMFAMEAILSNELFNLKLD 580
Query: 705 --------GHGW------RKVAPNSNETLGVSILKSRGFFPQAYWY-----WIGVGALIG 745
G + K TLG ++ R + Y W G +IG
Sbjct: 581 CHESIIPRGEYYDNISFSHKACAWQGATLGNDYVRGRDYLKSGLKYTYHHVWRNFGIIIG 640
Query: 746 YVFLFNFLFALALHFLSPFRKDQAGLSQEKLQERNASTDEEFIQSQQQENSSNTKMDEEV 805
++ F F LA +++P + L +R F+ SQ++ N S ++ V
Sbjct: 641 FLCFFLFCSLLAAEYITPLFTRENLLRWNNYLKRYCP----FLNSQKKNNKSAITNNDGV 696
Query: 806 SENKASSSGRKGMVLPFQPLSLTFDDITYSVDMPQ--------------------GMKNQ 845
K + +S +D Y++ P KN
Sbjct: 697 CTPKTPIANFSTSSSSVPSVSHQYDT-DYNIKHPDETVNNHTKESVAMETQKHVISWKNI 755
Query: 846 GVTEDRLELLKGVSGAFRPGVLTALMGVSGAGKTTLMDVLAGIKTSGYIEGNIKVSGYQ- 904
T +L+ SG G LTALMG SGAGKTTL++VL+ SG + G + + G
Sbjct: 756 NYTIGDKKLINDASGYISSG-LTALMGESGAGKTTLLNVLSQRTESGVVTGELLIDGQPL 814
Query: 905 KNQKSFARISGYCEQFDIHSPNVTVYESLLYSAWLRLSPEVDHATRKMFIEEVMELVELN 964
N +F R G+ +Q D+H +TV ESL S LR + D ++ V L+ L
Sbjct: 815 TNIDAFRRSIGFVQQQDVHLELLTVRESLEISCVLRGDGDRD------YLGVVSNLLRLP 868
Query: 965 SLREALVGLPGENGLSTEQRKRLTIAVELVANPSII-FMDEPTSGLDARAAAIVMRTVRN 1023
S E LV LS QRK L+I VELV PS++ F+DEPTSGLDA AA +++ ++
Sbjct: 869 S--EKLVA-----DLSPTQRKLLSIGVELVTKPSLLLFLDEPTSGLDAEAALTIVQFLKK 921
Query: 1024 TVDTGRTVVCTIHQPSIDIFDSFDELLLLKLGGEQIYAGPIGNQCSDLIQYFEAIQGVPT 1083
G+ ++CTIHQPS + FD + LLK GGE +Y G + N C YF A T
Sbjct: 922 LSMQGQAILCTIHQPSKSVISYFDNIYLLKRGGECVYFGSLPNAC----DYFVAHDRRLT 977
Query: 1084 I-KDGYNPATWMLEITSAGK-----------------------EANLKVNFTDVYKNS-E 1118
++ NPA +++++ +G + + +N+ +++++S E
Sbjct: 978 FDREMDNPADFVIDVVGSGSTNIPMDDAEKPTSSKIDEPVSYHKQSDSINWAELWQSSPE 1037
Query: 1119 LHRRNKQLIQELSVPSQSSKDLHFDAQYSQTFLAQCTYCLWKQHLSYWRNTSYTAVRLLF 1178
R L+ +S D +++ Q +Q++ R+ +Y +
Sbjct: 1038 KVRVADDLLLLEEEARKSGVDFTTSVWSPPSYMEQIKLITKRQYICTKRDMTYVFAKYAL 1097
Query: 1179 TIMTGILFGLIFWGVGAKSKKEQD-LFNAMGSMYAAVTFIGVVNGASVQPIVAIERTVFY 1237
G+ G FW QD +F + + I V ++Q +
Sbjct: 1098 NAGAGLFIGFSFWRTKHNINGLQDAIFLCFMMLCVSSPLINQVQDKALQS----KEVYIA 1153
Query: 1238 RERAAGMYSAMPYALAQVIIELPHILVQAVVYGIIVYAMMGFEWTASKVLWNLFFTYFSF 1297
RE + Y +AQ I+ELP + + ++ + Y GFE T+++V + Y F
Sbjct: 1154 REARSNTYHWTVLLIAQTIVELPLAISSSTLFFLCCYFCCGFE-TSARVAGVFYLNYILF 1212
Query: 1298 -LYYTYYGMMTMAITPNPHVAGILSTSFYAIWCLFSGFIIPLSRIPIWWKWYYWICPVAW 1356
+YY +G+ + P+ A + Y+ F G + P S P +W + Y + P +
Sbjct: 1213 SMYYLSFGLWLLYSAPDLQTAAVFVAFLYSFTASFCGVMQPYSLFPRFWTFMYRVSPYTY 1272
Query: 1357 TLNGLVT 1363
+ V+
Sbjct: 1273 FIETFVS 1279
Score = 66.6 bits (161), Expect = 5e-10
Identities = 105/492 (21%), Positives = 205/492 (41%), Gaps = 87/492 (17%)
Query: 154 ILQNVSGILKPRRMTLLLGPPGSGKTTLLLALA-----GILGKDLKQSGRVTYNGKGLEE 208
++ + SG + +T L+G G+GKTTLL L+ G++ +L G+ N ++
Sbjct: 764 LINDASGYISSG-LTALMGESGAGKTTLLNVLSQRTESGVVTGELLIDGQPLTN---IDA 819
Query: 209 FVPQRTSAYVSQYDNHIGEMTVRETLAFSARCQGVGQNYEMLTELLRKEKESKIEPDPDI 268
F +R+ +V Q D H+ +TVRE+L S +G G
Sbjct: 820 F--RRSIGFVQQQDVHLELLTVRESLEISCVLRGDGDR---------------------- 855
Query: 269 NAYMKEAAIEGHQNSVVIDYILKILGLDVCADTMVGDQMIRGISGGEKKRLTTG-EMLVG 327
DY LG+ + ++++ +S ++K L+ G E++
Sbjct: 856 ------------------DY----LGVVSNLLRLPSEKLVADLSPTQRKLLSIGVELVTK 893
Query: 328 PIKVLFMDEISNGLDSSTTFQIINSIKQSIHILNGTALVSLLQPAPETYELFDDIILL-T 386
P +LF+DE ++GLD+ I+ +K+ + + L ++ QP+ FD+I LL
Sbjct: 894 PSLLLFLDEPTSGLDAEAALTIVQFLKK-LSMQGQAILCTIHQPSKSVISYFDNIYLLKR 952
Query: 387 DGQIVYQGPREYVLEFFESTGFKCP---ERKGVADFLQEVTSRKD--------QWQYWAR 435
G+ VY G ++F + + E ADF+ +V + ++
Sbjct: 953 GGECVYFGSLPNACDYFVAHDRRLTFDREMDNPADFVIDVVGSGSTNIPMDDAEKPTSSK 1012
Query: 436 EDEPYNFVTVKDFARAFELFHIGKQ---LGEELADPFDKSK-----FHSNVLITKKYGIN 487
DEP ++ D EL+ + + ++L ++++ F ++V Y
Sbjct: 1013 IDEPVSYHKQSDSINWAELWQSSPEKVRVADDLLLLEEEARKSGVDFTTSVWSPPSY--- 1069
Query: 488 KKELLRACASRELLLMKRNSFVYIFKATQLTYLATLTTTL-FLRTKMYHSTIEDAQTYMG 546
E ++ R+ + KR+ Y+F L A L F RTK + ++DA ++
Sbjct: 1070 -MEQIKLITKRQYICTKRD-MTYVFAKYALNAGAGLFIGFSFWRTKHNINGLQDA-IFLC 1126
Query: 547 ALFFTVTVAMFNGISELNMTIMKLPIFYKQRDLLFYPSWAYSL-PPWILKIPITIIEVAI 605
+ V+ + N + + + ++ I + R ++ W L I+++P+ I +
Sbjct: 1127 FMMLCVSSPLINQVQDKALQSKEVYIAREARSNTYH--WTVLLIAQTIVELPLAISSSTL 1184
Query: 606 WECISYYAIGFD 617
+ Y+ GF+
Sbjct: 1185 FFLCCYFCCGFE 1196
>ABG1_HUMAN (P45844) ATP-binding cassette, sub-family G, member 1
(White protein homolog) (ATP-binding cassette transporter
8)
Length = 678
Score = 224 bits (570), Expect = 2e-57
Identities = 184/608 (30%), Positives = 306/608 (50%), Gaps = 65/608 (10%)
Query: 795 NSSNTKMDEEVSE-NKASSSGRKGMVLPFQPLSLTFDDITYSVDMPQGMKNQGVTEDRLE 853
N K+D ++E + SS R+ V ++ F D++YSV + +G
Sbjct: 50 NGHLKKVDNNLTEAQRFSSLPRRAAV------NIEFRDLSYSVPEGPWWRKKGYKT---- 99
Query: 854 LLKGVSGAFRPGVLTALMGVSGAGKTTLMDVLAGIKTSGYIEGNIKVSGYQKNQKSFARI 913
LLKG+SG F G L A+MG SGAGK+TLM++LAG + +G ++G + ++G ++ + F ++
Sbjct: 100 LLKGISGKFNSGELVAIMGPSGAGKSTLMNILAGYRETG-MKGAVLINGLPRDLRCFRKV 158
Query: 914 SGYCEQFDIHSPNVTVYESLLYSAWLRLSPEVDHATRKMFIEEVMELVELNSLREALVGL 973
S Y Q D+ P++TV E+++ SA L+L E D R+M ++E++ + L S G
Sbjct: 159 SCYIMQDDMLLPHLTVQEAMMVSAHLKLQ-EKDEGRREM-VKEILTALGLLSCANTRTG- 215
Query: 974 PGENGLSTEQRKRLTIAVELVANPSIIFMDEPTSGLDARAAAIVMRTVRNTVDTGRTVVC 1033
LS QRKRL IA+ELV NP ++F DEPTSGLD+ + V+ ++ GR+++C
Sbjct: 216 ----SLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVVSLMKGLAQGGRSIIC 271
Query: 1034 TIHQPSIDIFDSFDELLLLKLGGEQIYAGPIGNQCSDLIQYFEAI-QGVPTIKDGYNPAT 1092
TIHQPS +F+ FD+L +L G+ +Y G + N L+ Y + PT +NPA
Sbjct: 272 TIHQPSAKLFELFDQLYVLS-QGQCVYRGKVCN----LVPYLRDLGLNCPTY---HNPAD 323
Query: 1093 WMLEITS------------AGKE------------ANLKVNFTDVYKNSELHRRNKQLIQ 1128
+++E+ S A +E + +VN ++ SE ++ K+L +
Sbjct: 324 FVMEVASGEYGDQNSRLVRAVREGMCDSDHKRDLGGDAEVNPFLWHRPSEEVKQTKRL-K 382
Query: 1129 ELSVPSQSSKDLHFDAQYSQTFLAQCTYCLWKQHLSYWRNTSYTAVRLLFTIMTGILFGL 1188
L S S + H +S + L Q + LS R++ T +R+ I G+L GL
Sbjct: 383 GLRKDSSSMEGCH---SFSASCLTQFCILFKRTFLSIMRDSVLTHLRITSHIGIGLLIGL 439
Query: 1189 IFWGVGAKSKKEQDLFNAMGSMYAAVTFIGVVNGASVQPIV---AIERTVFYRERAAGMY 1245
++ G+G ++KK + + G ++ ++ F+ A++ P V +E VF RE Y
Sbjct: 440 LYLGIGNEAKK---VLSNSGFLFFSMLFLMF---AALMPTVLTFPLEMGVFLREHLNYWY 493
Query: 1246 SAMPYALAQVIIELPHILVQAVVYGIIVYAMMGFEWTASKVLWNLFFTYFSFLYYTYYGM 1305
S Y LA+ + ++P ++ V Y IVY M A + + + L G+
Sbjct: 494 SLKAYYLAKTMADVPFQIMFPVAYCSIVYWMTSQPSDAVRFVLFAALGTMTSLVAQSLGL 553
Query: 1306 MTMAITPNPHVAGILSTSFYAIWCLFSGFIIPLSRIPIWWKWYYWICPVAWTLNGLVTSQ 1365
+ A + + VA + LFSGF + IP + +W +I V + G++ S
Sbjct: 554 LIGAASTSLQVATFVGPVTAIPVLLFSGFFVSFDTIPTYLQWMSYISYVRYGFEGVILSI 613
Query: 1366 YGHNMDTL 1373
YG + + L
Sbjct: 614 YGLDREDL 621
Score = 134 bits (338), Expect = 1e-30
Identities = 137/566 (24%), Positives = 249/566 (43%), Gaps = 71/566 (12%)
Query: 154 ILQNVSGILKPRRMTLLLGPPGSGKTTLLLALAGILGKDLKQSGRVTYNGKGLEEFVPQR 213
+L+ +SG + ++GP G+GK+TL+ LAG +K G V NG + ++
Sbjct: 100 LLKGISGKFNSGELVAIMGPSGAGKSTLMNILAGYRETGMK--GAVLINGLPRDLRCFRK 157
Query: 214 TSAYVSQYDNHIGEMTVRETLAFSARCQGVGQNYEMLTELLRKEKESKIEPDPDINAYMK 273
S Y+ Q D + +TV+E + SA + L+++ E + E
Sbjct: 158 VSCYIMQDDMLLPHLTVQEAMMVSAHLK------------LQEKDEGRRE---------- 195
Query: 274 EAAIEGHQNSVVIDYILKILGLDVCADTMVGDQMIRGISGGEKKRLTTGEMLVGPIKVLF 333
++ IL LGL CA+T G +SGG++KRL LV V+F
Sbjct: 196 -----------MVKEILTALGLLSCANTRTGS-----LSGGQRKRLAIALELVNNPPVMF 239
Query: 334 MDEISNGLDSSTTFQIINSIKQSIHILNGTALVSLL-QPAPETYELFDDIILLTDGQIVY 392
DE ++GLDS++ FQ+++ +K G +++ + QP+ + +ELFD + +L+ GQ VY
Sbjct: 240 FDEPTSGLDSASCFQVVSLMKGLAQ--GGRSIICTIHQPSAKLFELFDQLYVLSQGQCVY 297
Query: 393 QGPREYVLEFFESTGFKCPERKGVADFLQEVTSRKDQWQYWAREDEPYNFVTVKDFARAF 452
+G ++ + G CP ADF+ EV S E N V+
Sbjct: 298 RGKVCNLVPYLRDLGLNCPTYHNPADFVMEVAS---------GEYGDQNSRLVRAVREGM 348
Query: 453 -ELFHIGKQLGEELADPFDKSKFHSNVLITKKY-GINK--------KELLRACASRELLL 502
+ H G+ +PF + V TK+ G+ K +C ++ +L
Sbjct: 349 CDSDHKRDLGGDAEVNPFLWHRPSEEVKQTKRLKGLRKDSSSMEGCHSFSASCLTQFCIL 408
Query: 503 MKRNSFVYIFKATQLTYLATLTTTL---FLRTKMYHSTIEDAQTYM---GALFFTVTVAM 556
KR +F+ I + + LT+L +T+ + L +Y +A+ + G LFF++ M
Sbjct: 409 FKR-TFLSIMRDSVLTHL-RITSHIGIGLLIGLLYLGIGNEAKKVLSNSGFLFFSMLFLM 466
Query: 557 FNGISELNMTI-MKLPIFYKQRDLLFYPSWAYSLPPWILKIPITIIEVAIWECISYYAIG 615
F + +T +++ +F ++ +Y AY L + +P I+ + I Y+
Sbjct: 467 FAALMPTVLTFPLEMGVFLREHLNYWYSLKAYYLAKTMADVPFQIMFPVAYCSIVYWMTS 526
Query: 616 FDPNIGRFFKQSLVVLCINQMASALFRFMAALGRDIVVANTFGTFSLLAVTVLGGFVISR 675
+ RF + + + +A +L + A + VA G + + V + GF +S
Sbjct: 527 QPSDAVRFVLFAALGTMTSLVAQSLGLLIGAASTSLQVATFVGPVTAIPVLLFSGFFVSF 586
Query: 676 EDVHKWFLWGYWSSPLMYGQNAIAVN 701
+ + + W + S + YG + ++
Sbjct: 587 DTIPTYLQWMSYISYVRYGFEGVILS 612
>ABG4_HUMAN (Q9H172) ATP-binding cassette, sub-family G, member 4
Length = 646
Score = 216 bits (550), Expect = 4e-55
Identities = 172/571 (30%), Positives = 284/571 (49%), Gaps = 37/571 (6%)
Query: 807 ENKASSSGRKGMVLPFQPLSLTFDDITYSVDMPQGMKNQGVTEDRLELLKGVSGAFRPGV 866
EN + + R + + + F +++YSV + +G LLK +SG F
Sbjct: 41 ENHITEAQRFSHLPKRSAVDIEFVELSYSVREGPCWRKRGYKT----LLKCLSGKFCRRE 96
Query: 867 LTALMGVSGAGKTTLMDVLAGIKTSGYIEGNIKVSGYQKNQKSFARISGYCEQFDIHSPN 926
L +MG SGAGK+T M++LAG + SG ++G I V+G + ++F ++S Y Q D+ P+
Sbjct: 97 LIGIMGPSGAGKSTFMNILAGYRESG-MKGQILVNGRPRELRTFRKMSCYIMQDDMLLPH 155
Query: 927 VTVYESLLYSAWLRLSPEVDHATRKMFIEEVMELVELNSLREALVGLPGENGLSTEQRKR 986
+TV E+++ SA L+LS + + +K + E++ + L S L LS QRKR
Sbjct: 156 LTVLEAMMVSANLKLSEKQE--VKKELVTEILTALGLMSCSHTRTAL-----LSGGQRKR 208
Query: 987 LTIAVELVANPSIIFMDEPTSGLDARAAAIVMRTVRNTVDTGRTVVCTIHQPSIDIFDSF 1046
L IA+ELV NP ++F DEPTSGLD+ + V+ +++ GRT++CTIHQPS +F+ F
Sbjct: 209 LAIALELVNNPPVMFFDEPTSGLDSASCFQVVSLMKSLAQGGRTIICTIHQPSAKLFEMF 268
Query: 1047 DELLLLKLGGEQIYAGPIGNQCSDLIQYFEAI-QGVPTIKDGYNPATWMLEITSAGKEAN 1105
D+L +L G+ I+ G + N LI Y + + PT +NPA +++E+ S G+ +
Sbjct: 269 DKLYILS-QGQCIFKGVVTN----LIPYLKGLGLHCPTY---HNPADFIIEVAS-GEYGD 319
Query: 1106 LKVNFTDVYKNSELHRRNKQLIQELS------VPSQSSKDLHFDAQYSQTFLAQCTYCLW 1159
L +N K+ E + P D ++ + L Q
Sbjct: 320 LNPMLFRAVQNGLCAMAEKKSSPEKNEVPAPCPPCPPEVDPIESHTFATSTLTQFCILFK 379
Query: 1160 KQHLSYWRNTSYTAVRLLFTIMTGILFGLIFWGVGAKSKKEQDLFNAMGSMYAAVTFIGV 1219
+ LS R+T T +R + ++ G+L GL++ +G + K +FN G ++ ++ F+
Sbjct: 380 RTFLSILRDTVLTHLRFMSHVVIGVLIGLLYLHIGDDASK---VFNNTGCLFFSMLFLMF 436
Query: 1220 VNGASVQPIV---AIERTVFYRERAAGMYSAMPYALAQVIIELPHILVQAVVYGIIVYAM 1276
A++ P V +E VF RE YS Y LA+ + ++P +V VVY IVY M
Sbjct: 437 ---AALMPTVLTFPLEMAVFMREHLNYWYSLKAYYLAKTMADVPFQVVCPVVYCSIVYWM 493
Query: 1277 MGFEWTASKVLWNLFFTYFSFLYYTYYGMMTMAITPNPHVAGILSTSFYAIWCLFSGFII 1336
G S+ L + L G++ A + + VA + LFSGF +
Sbjct: 494 TGQPAETSRFLLFSALATATALVAQSLGLLIGAASNSLQVATFVGPVTAIPVLLFSGFFV 553
Query: 1337 PLSRIPIWWKWYYWICPVAWTLNGLVTSQYG 1367
IP + +W ++ V + G++ + YG
Sbjct: 554 SFKTIPTYLQWSSYLSYVRYGFEGVILTIYG 584
Score = 137 bits (346), Expect = 2e-31
Identities = 130/556 (23%), Positives = 240/556 (42%), Gaps = 80/556 (14%)
Query: 154 ILQNVSGILKPRRMTLLLGPPGSGKTTLLLALAGILGKDLKQSGRVTYNGKGLEEFVPQR 213
+L+ +SG R + ++GP G+GK+T + LAG +K G++ NG+ E ++
Sbjct: 84 LLKCLSGKFCRRELIGIMGPSGAGKSTFMNILAGYRESGMK--GQILVNGRPRELRTFRK 141
Query: 214 TSAYVSQYDNHIGEMTVRETLAFSARCQGVGQNYEMLTELLRKEKESKIEPDPDINAYMK 273
S Y+ Q D + +TV E + SA + L +++E K E
Sbjct: 142 MSCYIMQDDMLLPHLTVLEAMMVSANLK------------LSEKQEVKKE---------- 179
Query: 274 EAAIEGHQNSVVIDYILKILGLDVCADTMVGDQMIRGISGGEKKRLTTGEMLVGPIKVLF 333
++ IL LGL C+ T +SGG++KRL LV V+F
Sbjct: 180 -----------LVTEILTALGLMSCSHTRTAL-----LSGGQRKRLAIALELVNNPPVMF 223
Query: 334 MDEISNGLDSSTTFQIINSIKQSIHILNGTALVSLLQPAPETYELFDDIILLTDGQIVYQ 393
DE ++GLDS++ FQ++ S+ +S+ T + ++ QP+ + +E+FD + +L+ GQ +++
Sbjct: 224 FDEPTSGLDSASCFQVV-SLMKSLAQGGRTIICTIHQPSAKLFEMFDKLYILSQGQCIFK 282
Query: 394 GPREYVLEFFESTGFKCPERKGVADFLQEVTSRKDQWQYWAREDEPYNFVTVKDFARAFE 453
G ++ + + G CP ADF+ EV S + + P F V++ A
Sbjct: 283 GVVTNLIPYLKGLGLHCPTYHNPADFIIEVASGE------YGDLNPMLFRAVQNGLCAMA 336
Query: 454 LFHIGKQLGEELA---------DPFDKSKFHSNVLITKKYGINKKELLRACASRELLLMK 504
+ E A DP + F ++ L + ++
Sbjct: 337 EKKSSPEKNEVPAPCPPCPPEVDPIESHTFATSTL------------------TQFCILF 378
Query: 505 RNSFVYIFKATQLTYLATLTTTLF--LRTKMYHSTIEDAQTYM---GALFFTVTVAMFNG 559
+ +F+ I + T LT+L ++ + L +Y +DA G LFF++ MF
Sbjct: 379 KRTFLSILRDTVLTHLRFMSHVVIGVLIGLLYLHIGDDASKVFNNTGCLFFSMLFLMFAA 438
Query: 560 ISELNMTI-MKLPIFYKQRDLLFYPSWAYSLPPWILKIPITIIEVAIWECISYYAIGFDP 618
+ +T +++ +F ++ +Y AY L + +P ++ ++ I Y+ G
Sbjct: 439 LMPTVLTFPLEMAVFMREHLNYWYSLKAYYLAKTMADVPFQVVCPVVYCSIVYWMTGQPA 498
Query: 619 NIGRFFKQSLVVLCINQMASALFRFMAALGRDIVVANTFGTFSLLAVTVLGGFVISREDV 678
RF S + +A +L + A + VA G + + V + GF +S + +
Sbjct: 499 ETSRFLLFSALATATALVAQSLGLLIGAASNSLQVATFVGPVTAIPVLLFSGFFVSFKTI 558
Query: 679 HKWFLWGYWSSPLMYG 694
+ W + S + YG
Sbjct: 559 PTYLQWSSYLSYVRYG 574
>WHIT_DROME (P10090) White protein
Length = 687
Score = 206 bits (524), Expect = 4e-52
Identities = 168/591 (28%), Positives = 280/591 (46%), Gaps = 59/591 (9%)
Query: 851 RLELLKGVSGAFRPGVLTALMGVSGAGKTTLMDVLA-----GIKTSGYIEGNIKVSGYQK 905
R LLK V G PG L A+MG SGAGKTTL++ LA GI+ S G ++G
Sbjct: 109 RKHLLKNVCGVAYPGELLAVMGSSGAGKTTLLNALAFRSPQGIQVSP--SGMRLLNGQPV 166
Query: 906 NQKSFARISGYCEQFDIHSPNVTVYESLLYSAWLRLSPEVDHATRKMFIEEVMELVELNS 965
+ K Y +Q D+ ++T E L++ A +R+ + + R +++V++ + L+
Sbjct: 167 DAKEMQARCAYVQQDDLFIGSLTAREHLIFQAMVRMPRHLTYRQRVARVDQVIQELSLSK 226
Query: 966 LREALVGLPGE-NGLSTEQRKRLTIAVELVANPSIIFMDEPTSGLDARAAAIVMRTVRNT 1024
+ ++G+PG GLS +RKRL A E + +P ++ DEPTSGLD+ A V++ ++
Sbjct: 227 CQHTIIGVPGRVKGLSGGERKRLAFASEALTDPPLLICDEPTSGLDSFTAHSVVQVLKKL 286
Query: 1025 VDTGRTVVCTIHQPSIDIFDSFDELLLLKLGGEQIYAGPIGNQCSDLIQYFEAIQG-VPT 1083
G+TV+ TIHQPS ++F+ FD++LL+ G P S+ + +F + PT
Sbjct: 287 SQKGKTVILTIHQPSSELFELFDKILLMAEGRVAFLGTP-----SEAVDFFSYVGAQCPT 341
Query: 1084 IKDGYNPATWMLEITSA--GKEANLKVNFTDVYKN---SELHRRNKQLI--QELSVPSQS 1136
YNPA + +++ + G+E + + N S++ R +QL+ + L P +
Sbjct: 342 ---NYNPADFYVQVLAVVPGREIESRDRIAKICDNFAISKVARDMEQLLATKNLEKPLEQ 398
Query: 1137 SKDLHFDAQYSQTFLAQCTYCLWKQHLSYWRNTSYTAVRLLFTIMTGILFGLIFWGVGAK 1196
++ + Y T+ Q LW+ LS + VRL+ T M IL GLIF G +
Sbjct: 399 PENGY---TYKATWFMQFRAVLWRSWLSVLKEPLLVKVRLIQTTMVAILIGLIFLG---Q 452
Query: 1197 SKKEQDLFNAMGSMYAAVTFIGVVNGASVQPIVAIERTVFYRERAAGMYSAMPYALAQVI 1256
+ + N G+++ +T + N + + E VF RE + +Y Y L + I
Sbjct: 453 QLTQVGVMNINGAIFLFLTNMTFQNVFATINVFTSELPVFMREARSRLYRCDTYFLGKTI 512
Query: 1257 IELPHILVQAVVYGIIVYAMMG--------FEWTASKVLWNLFFTYFSFLYYTYYGMMTM 1308
ELP L +V+ I Y M+G F A L T F +L +M
Sbjct: 513 AELPLFLTVPLVFTAIAYPMIGLRAGVLHFFNCLALVTLVANVSTSFGYLISCASSSTSM 572
Query: 1309 AITPNPHVAGILSTSFYAIWCLFSGFIIPLSRIPIWWKWYYWICPVAWTLNGLVTSQY-- 1366
A++ P V + LF GF + +P++ KW ++ + GL+ +Q+
Sbjct: 573 ALSVGPPV--------IIPFLLFGGFFLNSGSVPVYLKWLSYLSWFRYANEGLLINQWAD 624
Query: 1367 ---------GHNMDTLDNGQSVEEFVR-NYFGFEYDFLGVVAIVVVSFSVL 1407
N +G+ + E + + D++G +AI++VSF VL
Sbjct: 625 VEPGEISCTSSNTTCPSSGKVILETLNFSAADLPLDYVG-LAILIVSFRVL 674
Score = 169 bits (427), Expect = 7e-41
Identities = 144/588 (24%), Positives = 257/588 (43%), Gaps = 58/588 (9%)
Query: 132 VNVIEGCLNNLQIIPSPKKQLHILQNVSGILKPRRMTLLLGPPGSGKTTLLLALA--GIL 189
VN G N + IP+P+K H+L+NV G+ P + ++G G+GKTTLL ALA
Sbjct: 92 VNRTRGLFCNERHIPAPRK--HLLKNVCGVAYPGELLAVMGSSGAGKTTLLNALAFRSPQ 149
Query: 190 GKDLKQSGRVTYNGKGLEEFVPQRTSAYVSQYDNHIGEMTVRETLAFSARCQGVGQNYEM 249
G + SG NG+ ++ Q AYV Q D IG +T RE L F A + M
Sbjct: 150 GIQVSPSGMRLLNGQPVDAKEMQARCAYVQQDDLFIGSLTAREHLIFQAMVR-------M 202
Query: 250 LTELLRKEKESKIEPDPDINAYMKEAAIEGHQNSVVIDYILKILGLDVCADTMVG-DQMI 308
L +++ +++ D +++ L L C T++G +
Sbjct: 203 PRHLTYRQRVARV------------------------DQVIQELSLSKCQHTIIGVPGRV 238
Query: 309 RGISGGEKKRLTTGEMLVGPIKVLFMDEISNGLDSSTTFQIINSIKQSIHILNGTALVSL 368
+G+SGGE+KRL + +L DE ++GLDS T ++ +K+ + T ++++
Sbjct: 239 KGLSGGERKRLAFASEALTDPPLLICDEPTSGLDSFTAHSVVQVLKK-LSQKGKTVILTI 297
Query: 369 LQPAPETYELFDDIILLTDGQIVYQGPREYVLEFFESTGFKCPERKGVADFLQEVTSRKD 428
QP+ E +ELFD I+L+ +G++ + G ++FF G +CP ADF +V +
Sbjct: 298 HQPSSELFELFDKILLMAEGRVAFLGTPSEAVDFFSYVGAQCPTNYNPADFYVQVLAVVP 357
Query: 429 QWQYWARE--DEPYNFVTVKDFARAFELFHIGKQLGEELADPFDKSKFHSNVLITKKYGI 486
+ +R+ + + + AR E K L + L P + + + +
Sbjct: 358 GREIESRDRIAKICDNFAISKVARDMEQLLATKNLEKPLEQPENGYTYKATWFMQ----- 412
Query: 487 NKKELLRACASRELLLMKRNSFVYIFKATQLTYLATLTTTLFLRTKMYHSTIEDAQTYMG 546
RA R L + + + + Q T +A L +FL ++ T G
Sbjct: 413 -----FRAVLWRSWLSVLKEPLLVKVRLIQTTMVAILIGLIFLGQQL---TQVGVMNING 464
Query: 547 ALFFTVTVAMF-NGISELNMTIMKLPIFYKQRDLLFYPSWAYSLPPWILKIPITIIEVAI 605
A+F +T F N + +N+ +LP+F ++ Y Y L I ++P+ + +
Sbjct: 465 AIFLFLTNMTFQNVFATINVFTSELPVFMREARSRLYRCDTYFLGKTIAELPLFLTVPLV 524
Query: 606 WECISYYAIGFDPNIGRFFKQSLVVLCINQMASALFRFMAALGRDIVVANTFGTFSLLAV 665
+ I+Y IG + FF +V + ++++ ++ +A + G ++
Sbjct: 525 FTAIAYPMIGLRAGVLHFFNCLALVTLVANVSTSFGYLISCASSSTSMALSVGPPVIIPF 584
Query: 666 TVLGGFVISREDVHKWFLWGYWSSPLMYGQNAIAVNEFLGHGWRKVAP 713
+ GGF ++ V + W + S Y + +N+ W V P
Sbjct: 585 LLFGGFFLNSGSVPVYLKWLSYLSWFRYANEGLLINQ-----WADVEP 627
>WHIT_CERCA (Q17320) White protein
Length = 679
Score = 206 bits (524), Expect = 4e-52
Identities = 173/660 (26%), Positives = 297/660 (44%), Gaps = 56/660 (8%)
Query: 790 SQQQENSSNTKMDEEVSENKASSSGRKGMVLPFQPLSLTFDDITYS-------------- 835
S + N++N + E+ S N+ G + P P +LT D++TYS
Sbjct: 19 SAESLNNNNEQPYEQSSINQGFCKNY-GTLSPPSP-ALTADNLTYSWYNLDVFGAVHQPG 76
Query: 836 ------VDMPQGM--KNQGVTEDRLELLKGVSGAFRPGVLTALMGVSGAGKTTLMDVLAG 887
V+ +G+ + + R LLK SG PG L A+MG SGAGKTTL++ A
Sbjct: 77 SSWKQLVNRVKGVFCNERHIPAPRKHLLKNDSGVAYPGELLAVMGSSGAGKTTLLNASAF 136
Query: 888 IKTSGY--IEGNIKV-SGYQKNQKSFARISGYCEQFDIHSPNVTVYESLLYSAWLRLSPE 944
+ G I++ +G+ + K Y +Q D+ ++T E L++ A +R+
Sbjct: 137 RSSKGVQISPSTIRMLNGHPVDAKEMQARCAYVQQDDLFIGSLTAREHLIFQAMVRMPRH 196
Query: 945 VDHATRKMFIEEVMELVELNSLREALVGLPGE-NGLSTEQRKRLTIAVELVANPSIIFMD 1003
+ + +++V++ + L + L+G+PG GLS +RKRL A E + +P ++ D
Sbjct: 197 MTQKQKVQRVDQVIQDLSLGKCQNTLIGVPGRVKGLSGGERKRLAFASEALTDPPLLICD 256
Query: 1004 EPTSGLDARAAAIVMRTVRNTVDTGRTVVCTIHQPSIDIFDSFDELLLLKLGGEQIYAGP 1063
EPTSGLD+ A V++ ++ G+TV+ TIHQPS ++F+ FD++LL+ G P
Sbjct: 257 EPTSGLDSFMAHSVVQVLKKLSQKGKTVILTIHQPSSELFELFDKILLMAEGRVAFLGTP 316
Query: 1064 IGNQCSDLIQYFEAIQGVPTIKDGYNPATWMLEITSA--GKEANLK---VNFTDVYKNSE 1118
+ D Y A T Y PA + +++ + G+E + D + +
Sbjct: 317 --GEAVDFFSYIGA-----TCPTNYTPADFYVQVLAVVPGREVESRDRVAKICDNFAVGK 369
Query: 1119 LHRRNKQLIQELSVPSQSSKDLHFDAQYSQTFLAQCTYCLWKQHLSYWRNTSYTAVRLLF 1178
+ R +Q Q+L + K+ + Y ++ Q LW+ LS + VRLL
Sbjct: 370 VSREMEQNFQKLVKSNGFGKEDENEYTYKASWFMQFRAVLWRSWLSVLKEPLLVKVRLLQ 429
Query: 1179 TIMTGILFGLIFWGVGAKSKKEQDLFNAMGSMYAAVTFIGVVNGASVQPIVAIERTVFYR 1238
T M +L GLIF G + + + N G+++ +T + N + + E VF R
Sbjct: 430 TTMVAVLIGLIFLG---QQLTQVGVMNINGAIFLFLTNMTFQNSFATITVFTTELPVFMR 486
Query: 1239 ERAAGMYSAMPYALAQVIIELPHILVQAVVYGIIVYAMMGFEWTASKVLWNLFFTYFSFL 1298
E + +Y Y L + I ELP LV ++ I Y ++G L
Sbjct: 487 ETRSRLYRCDTYFLGKTIAELPLFLVVPFLFTAIAYPLIGLRPGVDHFFTALALVTLVAN 546
Query: 1299 YYTYYGMMTMAITPNPHVAGILSTSFYAIWCLFSGFIIPLSRIPIWWKWYYWICPVAWTL 1358
T +G + + +A + + LF GF + +P+++KW ++ +
Sbjct: 547 VSTSFGYLISCACSSTSMALSVGPPVIIPFLLFGGFFLNSGSVPVYFKWLSYLSWFRYAN 606
Query: 1359 NGLVTSQY-----GHNMDTLDNG--QSVEEFVRNYFGFE-----YDFLGVVAIVVVSFSV 1406
GL+ +Q+ G TL N S E + F +DF+G +A+++V F +
Sbjct: 607 EGLLINQWADVKPGEITCTLSNTTCPSSGEVILETLNFSASDLPFDFIG-LALLIVGFRI 665
Score = 170 bits (430), Expect = 3e-41
Identities = 149/598 (24%), Positives = 261/598 (42%), Gaps = 77/598 (12%)
Query: 132 VNVIEGCLNNLQIIPSPKKQLHILQNVSGILKPRRMTLLLGPPGSGKTTLLLALA--GIL 189
VN ++G N + IP+P+K H+L+N SG+ P + ++G G+GKTTLL A A
Sbjct: 83 VNRVKGVFCNERHIPAPRK--HLLKNDSGVAYPGELLAVMGSSGAGKTTLLNASAFRSSK 140
Query: 190 GKDLKQSGRVTYNGKGLEEFVPQRTSAYVSQYDNHIGEMTVRETLAFSARCQGVGQNYEM 249
G + S NG ++ Q AYV Q D IG +T RE L F A + M
Sbjct: 141 GVQISPSTIRMLNGHPVDAKEMQARCAYVQQDDLFIGSLTAREHLIFQAMVR-------M 193
Query: 250 LTELLRKEKESKIEPDPDINAYMKEAAIEGHQNSVVIDYILKILGLDVCADTMVG-DQMI 308
+ +K+K + +D +++ L L C +T++G +
Sbjct: 194 PRHMTQKQKVQR------------------------VDQVIQDLSLGKCQNTLIGVPGRV 229
Query: 309 RGISGGEKKRLTTGEMLVGPIKVLFMDEISNGLDSSTTFQIINSIKQSIHILNGTALVSL 368
+G+SGGE+KRL + +L DE ++GLDS ++ +K+ + T ++++
Sbjct: 230 KGLSGGERKRLAFASEALTDPPLLICDEPTSGLDSFMAHSVVQVLKK-LSQKGKTVILTI 288
Query: 369 LQPAPETYELFDDIILLTDGQIVYQGPREYVLEFFESTGFKCPERKGVADFLQEVTSRKD 428
QP+ E +ELFD I+L+ +G++ + G ++FF G CP ADF +V +
Sbjct: 289 HQPSSELFELFDKILLMAEGRVAFLGTPGEAVDFFSYIGATCPTNYTPADFYVQVLAVVP 348
Query: 429 QWQYWAREDEPYNFVTVKDFARAFELFHIGKQLGEELADPFDKSKFHSNVLITKKYGINK 488
RE E + V A+ + F +GK + E+ F K + K G K
Sbjct: 349 -----GREVESRDRV-----AKICDNFAVGK-VSREMEQNFQK--------LVKSNGFGK 389
Query: 489 KE------------LLRACASRELLLMKRNSFVYIFKATQLTYLATLTTTLFLRTKMYHS 536
++ RA R L + + + + Q T +A L +FL ++
Sbjct: 390 EDENEYTYKASWFMQFRAVLWRSWLSVLKEPLLVKVRLLQTTMVAVLIGLIFLGQQL--- 446
Query: 537 TIEDAQTYMGALFFTVTVAMF-NGISELNMTIMKLPIFYKQRDLLFYPSWAYSLPPWILK 595
T GA+F +T F N + + + +LP+F ++ Y Y L I +
Sbjct: 447 TQVGVMNINGAIFLFLTNMTFQNSFATITVFTTELPVFMRETRSRLYRCDTYFLGKTIAE 506
Query: 596 IPITIIEVAIWECISYYAIGFDPNIGRFFKQSLVVLCINQMASALFRFMAALGRDIVVAN 655
+P+ ++ ++ I+Y IG P + FF +V + ++++ ++ +A
Sbjct: 507 LPLFLVVPFLFTAIAYPLIGLRPGVDHFFTALALVTLVANVSTSFGYLISCACSSTSMAL 566
Query: 656 TFGTFSLLAVTVLGGFVISREDVHKWFLWGYWSSPLMYGQNAIAVNEFLGHGWRKVAP 713
+ G ++ + GGF ++ V +F W + S Y + +N+ W V P
Sbjct: 567 SVGPPVIIPFLLFGGFFLNSGSVPVYFKWLSYLSWFRYANEGLLINQ-----WADVKP 619
>WHIT_ANOGA (Q27256) White protein
Length = 695
Score = 202 bits (514), Expect = 5e-51
Identities = 164/645 (25%), Positives = 296/645 (45%), Gaps = 55/645 (8%)
Query: 767 DQAGLSQEKLQERNASTDEEFIQSQQQENSSNTKMDEEVSENKA---------SSSGRKG 817
DQ G ++ K S+ + S Q+ S + ++ ++ +KA S KG
Sbjct: 7 DQYGDAESKT---TISSSRRYSSSSYQDQSMDDALNTTLTNDKATLIQVWKPKSYGSVKG 63
Query: 818 MVLPFQPLSLTFDDITYSVDMPQGMKNQGVTEDRLE---------------LLKGVSGAF 862
+ + L+ T+ +I + P K + RL LLK V+G
Sbjct: 64 QIPQCERLTYTWKEIDVFGEAPTDGKPREPLCTRLRNCCTRQRKDFNPRKHLLKNVTGVA 123
Query: 863 RPGVLTALMGVSGAGKTTLMDVLA-----GIKTSGYIEGNIKVSGYQKNQKSFARISGYC 917
+ G L A+MG SGAGKTTL++ LA G+K S ++G N + Y
Sbjct: 124 KSGELLAVMGSSGAGKTTLLNALAFRSPPGVKISP--NAVRALNGVPVNAEQLRARCAYV 181
Query: 918 EQFDIHSPNVTVYESLLYSAWLRLSPEVDHATRKMFIEEVMELVELNSLREALVGLPGE- 976
+Q D+ P++T E LL+ A LR+ +V + ++ ++EV++ + L + ++G PG
Sbjct: 182 QQDDLFIPSLTTREHLLFQAMLRMGRDVPASVKQHRVQEVLQELSLVKCADTIIGAPGRI 241
Query: 977 NGLSTEQRKRLTIAVELVANPSIIFMDEPTSGLDARAAAIVMRTVRNTVDTGRTVVCTIH 1036
GLS +RKRL A E + +P ++ DEPTSGLD+ A V++ ++ G+T++ TIH
Sbjct: 242 KGLSGGERKRLAFASETLTDPHLLLCDEPTSGLDSFMAHSVLQVLKGMAMKGKTIILTIH 301
Query: 1037 QPSIDIFDSFDELLLLKLGGEQIYAGPIGNQCSDLIQYFEAIQGVPTIKDGYNPATWMLE 1096
QPS +++ FD++LL+ G P + ++F + G+P YNPA + ++
Sbjct: 302 QPSSELYCLFDKILLVAEGRVAFLGSPYQS-----AEFFSQL-GIP-CPPNYNPADFYVQ 354
Query: 1097 I--TSAGKEANLKVNFTDVYKNSELHRRNKQLIQELSVPSQSSKDLHFDAQ--------Y 1146
+ + KEA + + + + +++++ SV + + + Q Y
Sbjct: 355 MLAIAPAKEAECRDMIKKICDSFAVSPIAREVLETASVAGKGMDEPYMLQQVEGVGSTGY 414
Query: 1147 SQTFLAQCTYCLWKQHLSYWRNTSYTAVRLLFTIMTGILFGLIFWGVGAKSKKEQDLFNA 1206
++ Q LW+ LS ++ VRLL T M L G I++G + + + N
Sbjct: 415 RSSWWTQFYCILWRSWLSVLKDPMLVKVRLLQTAMVATLIGSIYFG---QVLDQDGVMNI 471
Query: 1207 MGSMYAAVTFIGVVNGASVQPIVAIERTVFYRERAAGMYSAMPYALAQVIIELPHILVQA 1266
GS++ +T + N +V + + E VF RE+ + +Y Y L + I ELP +
Sbjct: 472 NGSLFLFLTNMTFQNVFAVINVFSAELPVFLREKRSRLYRVDTYFLGKTIAELPLFIAVP 531
Query: 1267 VVYGIIVYAMMGFEWTASKVLWNLFFTYFSFLYYTYYGMMTMAITPNPHVAGILSTSFYA 1326
V+ I Y M+G A+ L LF T +G + + + +A +
Sbjct: 532 FVFTSITYPMIGLRTGATHYLTTLFIVTLVANVSTSFGYLISCASSSISMALSVGPPVVI 591
Query: 1327 IWCLFSGFIIPLSRIPIWWKWYYWICPVAWTLNGLVTSQYGHNMD 1371
+ +F GF + + +P ++K+ ++ + L+ +Q+ +D
Sbjct: 592 PFLIFGGFFLNSASVPAYFKYLSYLSWFRYANEALLINQWSTVVD 636
Score = 144 bits (362), Expect = 2e-33
Identities = 136/568 (23%), Positives = 252/568 (43%), Gaps = 57/568 (10%)
Query: 147 SPKKQLHILQNVSGILKPRRMTLLLGPPGSGKTTLLLALA--GILGKDLKQSGRVTYNGK 204
+P+K H+L+NV+G+ K + ++G G+GKTTLL ALA G + + NG
Sbjct: 110 NPRK--HLLKNVTGVAKSGELLAVMGSSGAGKTTLLNALAFRSPPGVKISPNAVRALNGV 167
Query: 205 GLEEFVPQRTSAYVSQYDNHIGEMTVRETLAFSARCQGVGQNYEMLTELLRKEKESKIEP 264
+ + AYV Q D I +T RE L F A +LR +
Sbjct: 168 PVNAEQLRARCAYVQQDDLFIPSLTTREHLLFQA--------------MLRMGR------ 207
Query: 265 DPDINAYMKEAAIEGHQNSVVIDYILKILGLDVCADTMVG-DQMIRGISGGEKKRLTTGE 323
D+ A +K+ ++ +L+ L L CADT++G I+G+SGGE+KRL
Sbjct: 208 --DVPASVKQHRVQ---------EVLQELSLVKCADTIIGAPGRIKGLSGGERKRLAFAS 256
Query: 324 MLVGPIKVLFMDEISNGLDSSTTFQIINSIKQSIHILNGTALVSLLQPAPETYELFDDII 383
+ +L DE ++GLDS ++ +K + + T ++++ QP+ E Y LFD I+
Sbjct: 257 ETLTDPHLLLCDEPTSGLDSFMAHSVLQVLK-GMAMKGKTIILTIHQPSSELYCLFDKIL 315
Query: 384 LLTDGQIVYQGPREYVLEFFESTGFKCPERKGVADFLQEVTSRKDQWQYWARE--DEPYN 441
L+ +G++ + G EFF G CP ADF ++ + + R+ + +
Sbjct: 316 LVAEGRVAFLGSPYQSAEFFSQLGIPCPPNYNPADFYVQMLAIAPAKEAECRDMIKKICD 375
Query: 442 FVTVKDFARAFELFHIGKQLGEELADPFDKSKFHSNVLITKKYGINKKELLRACASRELL 501
V AR E+ G+ + +P+ ++ + G+ + ++
Sbjct: 376 SFAVSPIAR--EVLETASVAGKGMDEPY---------MLQQVEGVGSTGYRSSWWTQFYC 424
Query: 502 LMKRNSFVYIFKATQLTYLATLTTTLF--LRTKMYHSTIEDAQTYM---GALFFTVTVAM 556
++ R S++ + K L + L T + L +Y + D M G+LF +T
Sbjct: 425 ILWR-SWLSVLKDPMLVKVRLLQTAMVATLIGSIYFGQVLDQDGVMNINGSLFLFLTNMT 483
Query: 557 F-NGISELNMTIMKLPIFYKQRDLLFYPSWAYSLPPWILKIPITIIEVAIWECISYYAIG 615
F N + +N+ +LP+F +++ Y Y L I ++P+ I ++ I+Y IG
Sbjct: 484 FQNVFAVINVFSAELPVFLREKRSRLYRVDTYFLGKTIAELPLFIAVPFVFTSITYPMIG 543
Query: 616 FDPNIGRFFKQSLVVLCINQMASALFRFMAALGRDIVVANTFGTFSLLAVTVLGGFVISR 675
+ +V + ++++ ++ I +A + G ++ + GGF ++
Sbjct: 544 LRTGATHYLTTLFIVTLVANVSTSFGYLISCASSSISMALSVGPPVVIPFLIFGGFFLNS 603
Query: 676 EDVHKWFLWGYWSSPLMYGQNAIAVNEF 703
V +F + + S Y A+ +N++
Sbjct: 604 ASVPAYFKYLSYLSWFRYANEALLINQW 631
>YQ5C_CAEEL (Q09466) Putative ABC transporter C16C10.12 in chromosome
III
Length = 610
Score = 201 bits (512), Expect = 9e-51
Identities = 157/600 (26%), Positives = 292/600 (48%), Gaps = 39/600 (6%)
Query: 824 PLSLTFDDITYSVDMPQGMKNQGVTEDRLELLKGVSGAFRPGVLTALMGVSGAGKTTLMD 883
P+++T+++I K Q +LL VSG +PG + ALMG SGAGKTTLM+
Sbjct: 32 PITVTWENIEVKTRKKLFSKKQK------QLLNRVSGIAKPGEMVALMGASGAGKTTLMN 85
Query: 884 VLAGIKTSGYIE-GNIKVSGYQKNQKSFARISGYCEQFDIHSPNVTVYESLLYSAWLRLS 942
VL G + G +KV+G K K + ISG+ +Q +I P +TV E L+ A LR+
Sbjct: 86 VLMCRNMKGLEKNGTVKVNG-TKIGKEISLISGFAQQQEIFIPTLTVDEYLMIQARLRM- 143
Query: 943 PEVDHATRKMFIEEVMELVELNSLREALVGLPG-ENGLSTEQRKRLTIAVELVANPSIIF 1001
+ + TR+ ++E++E++ L + R+ +G PG G+S + +RLT A EL++NPS++F
Sbjct: 144 -KANKHTRRERVDEIIEMLRLQNCRDLKIGTPGLVKGISGGEARRLTFACELLSNPSLLF 202
Query: 1002 MDEPTSGLDARAAAIVMRTVRNTVDTGRTVVCTIHQPSIDIFDSFDELLLLKLGGEQIYA 1061
DEPTSGLD+ AA V++ ++N ++GRT+ IHQP+ ++F FD+++ L +G
Sbjct: 203 ADEPTSGLDSFMAASVVQILKNLANSGRTL---IHQPTAELFFQFDKIIFLSMGKTAFMG 259
Query: 1062 GPIGNQCSDLIQYFEAIQGVPTIKDGYNPATWMLEITSAGKEANLKVNFT-----DVYKN 1116
P + +++F A G P I +NP W+ S K T + Y+
Sbjct: 260 TP-----HESVKFF-ADCGHP-IPKLFNPPEWIQSKLSVIPNNETKSRETIGKIIEFYEK 312
Query: 1117 SELHRRNKQLIQELSVPSQSSKDLHFDAQYSQTFLAQCTYCLWKQHLSYWRNTSYTAVRL 1176
S +H+++ I E+ V + + + + + F A+ L + L R+ + ++L
Sbjct: 313 SIIHQKS---IVEIRVIATTELPPYIE---NPGFFAETGALLKRACLDVIRSPAQMRMKL 366
Query: 1177 LFTIMTGILFGLIFWGVGAKSKKEQDLFNAMGSMYAAVTFIGVVNGASVQPIVAIERTVF 1236
+ ++ G+ G ++W + ++ +A+ + A +TF + + + E +
Sbjct: 367 IQKVVMGLFIGSLYWQQPLDPRGVRNTNSALYFLIAELTFSTMF---GIMTFMEHELPLI 423
Query: 1237 YRERAAGMYSAMPYALAQVIIELPHILVQAVVYGIIVYAMMGFEWTASKVLWNLFFTYFS 1296
RE G++ + Y +++ + LP + + +I Y M+G T +V ++ +
Sbjct: 424 AREYHDGLFYVISYYISRFLSYLPLFTIDGALMIVISYWMIGLNSTWQQVAKSILISVLV 483
Query: 1297 FLYYTYYGMMTMAITPNPHVAGILSTSFYAIWCLFSGFIIPLSRIPIWWKWYYWICPVAW 1356
T G+ + +A + ++ L SG + P++ +W W +
Sbjct: 484 EQSATSCGLFLACLFETTSLAIAFAVPASGLFALLSGLYGNTNNFPVYIRWMQWTSWCRY 543
Query: 1357 TLNGLVTSQYGH----NMDTLDNGQSVEEFVRNYFGFEYDFLGVVAIVVVSFSVLFALIF 1412
GLV +Q+ D +++F N ++ D +G+ +IV+ + + +F
Sbjct: 544 GFEGLVVNQWSQVDNPKWDPFYRELILKQFSFNKDNYQLDVIGLCSIVIFFYLAGYIALF 603
Score = 128 bits (321), Expect = 1e-28
Identities = 140/577 (24%), Positives = 243/577 (41%), Gaps = 96/577 (16%)
Query: 149 KKQLHILQNVSGILKPRRMTLLLGPPGSGKTTLLLALAGILGKDLKQSGRVTYNGKGLEE 208
KKQ +L VSGI KP M L+G G+GKTTL+ L K L+++G V NG + +
Sbjct: 51 KKQKQLLNRVSGIAKPGEMVALMGASGAGKTTLMNVLMCRNMKGLEKNGTVKVNGTKIGK 110
Query: 209 FVPQRTSAYVSQYDNHIGEMTVRETLAFSARCQGVGQNYEMLTELLRKEKESKIEPDPDI 268
+ S + Q + I +TV E L AR + ++ K ++ E
Sbjct: 111 EI-SLISGFAQQQEIFIPTLTVDEYLMIQARLR------------MKANKHTRRER---- 153
Query: 269 NAYMKEAAIEGHQNSVVIDYILKILGLDVCADTMVGDQ-MIRGISGGEKKRLTTGEMLVG 327
+D I+++L L C D +G +++GISGGE +RLT L+
Sbjct: 154 -----------------VDEIIEMLRLQNCRDLKIGTPGLVKGISGGEARRLTFACELLS 196
Query: 328 PIKVLFMDEISNGLDSSTTFQIINSIKQSIHILNGTALVSLLQPAPETYELFDDIILLTD 387
+LF DE ++GLDS ++ +K + +G L+ QP E + FD II L+
Sbjct: 197 NPSLLFADEPTSGLDSFMAASVVQILKNLAN--SGRTLIH--QPTAELFFQFDKIIFLSM 252
Query: 388 GQIVYQGPREYVLEFFESTGFKCPERKGVADFLQEVTSRKDQWQYWAREDEPYNFVTVKD 447
G+ + G ++FF G P+ +++Q S + +RE
Sbjct: 253 GKTAFMGTPHESVKFFADCGHPIPKLFNPPEWIQSKLSVIPNNETKSRET---------- 302
Query: 448 FARAFELFHIGKQLGEELADPFDKSKFHSNVLITKKYGINKKELLRACASREL------- 500
IGK + + ++KS H ++ +R A+ EL
Sbjct: 303 ---------IGK-----IIEFYEKSIIHQKSIVE----------IRVIATTELPPYIENP 338
Query: 501 -------LLMKRNSFVYIFKATQ--LTYLATLTTTLFLRTKMYHSTIE--DAQTYMGALF 549
L+KR I Q + + + LF+ + + ++ + AL+
Sbjct: 339 GFFAETGALLKRACLDVIRSPAQMRMKLIQKVVMGLFIGSLYWQQPLDPRGVRNTNSALY 398
Query: 550 FTVTVAMFNGISELNMTIM--KLPIFYKQ-RDLLFYPSWAYSLPPWILKIPITIIEVAIW 606
F + F+ + + MT M +LP+ ++ D LFY +Y + ++ +P+ I+ A+
Sbjct: 399 FLIAELTFSTMFGI-MTFMEHELPLIAREYHDGLFYVI-SYYISRFLSYLPLFTIDGALM 456
Query: 607 ECISYYAIGFDPNIGRFFKQSLVVLCINQMASALFRFMAALGRDIVVANTFGTFSLLAVT 666
ISY+ IG + + K L+ + + Q A++ F+A L +A F +
Sbjct: 457 IVISYWMIGLNSTWQQVAKSILISVLVEQSATSCGLFLACLFETTSLAIAFAVPASGLFA 516
Query: 667 VLGGFVISREDVHKWFLWGYWSSPLMYGQNAIAVNEF 703
+L G + + + W W+S YG + VN++
Sbjct: 517 LLSGLYGNTNNFPVYIRWMQWTSWCRYGFEGLVVNQW 553
Database: sprot
Posted date: Nov 25, 2004 10:54 AM
Number of letters in database: 59,974,054
Number of sequences in database: 164,201
Lambda K H
0.322 0.138 0.410
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 163,643,166
Number of Sequences: 164201
Number of extensions: 7176648
Number of successful extensions: 28626
Number of sequences better than 10.0: 1024
Number of HSP's better than 10.0 without gapping: 740
Number of HSP's successfully gapped in prelim test: 297
Number of HSP's that attempted gapping in prelim test: 24336
Number of HSP's gapped (non-prelim): 3448
length of query: 1424
length of database: 59,974,054
effective HSP length: 123
effective length of query: 1301
effective length of database: 39,777,331
effective search space: 51750307631
effective search space used: 51750307631
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 72 (32.3 bits)
Medicago: description of AC144617.9