BLAST2 result
BLASTP 2.2.2 [Dec-14-2001]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= AC144564.17 - phase: 0
(559 letters)
Database: sprot
164,201 sequences; 59,974,054 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
BRD3_MOUSE (Q8K2F0) Bromodomain-containing protein 3 (Bromodomai... 140 9e-33
BRD3_HUMAN (Q15059) Bromodomain-containing protein 3 (RING3-like... 136 2e-31
BRD4_HUMAN (O60885) Bromodomain-containing protein 4 (HUNK1 prot... 127 8e-29
BRD4_MOUSE (Q9ESU6) Bromodomain-containing protein 4 (Mitotic ch... 126 1e-28
BDF1_YEAST (P35817) BDF1 protein 115 4e-25
YCK2_SCHPO (Q9Y7N0) Hypothetical bromodomain protein C1450.02 103 1e-21
BRD2_HUMAN (P25440) Bromodomain-containing protein 2 (RING3 prot... 103 2e-21
FSH_DROME (P13709) Female sterile homeotic protein (Fragile-chor... 99 2e-20
YK82_SCHPO (Q9HGP4) Hypothetical bromodomain protein C631.02 91 6e-18
CBP_MOUSE (P45481) CREB-binding protein (EC 2.3.1.48) 78 5e-14
CBP_HUMAN (Q92793) CREB-binding protein (EC 2.3.1.48) 76 2e-13
P300_HUMAN (Q09472) E1A-associated protein p300 (EC 2.3.1.48) 75 6e-13
WDR9_HUMAN (Q9NSI6) WD-repeat protein 9 72 3e-12
BA1B_HUMAN (Q9UIG0) Bromodomain adjacent to zinc finger domain p... 71 8e-12
BA1B_MOUSE (Q9Z277) Bromodomain adjacent to zinc finger domain p... 69 4e-11
TF1A_HUMAN (O15164) Transcription intermediary factor 1-alpha (T... 68 6e-11
CBP1_CAEEL (P34545) Protein cbp-1 66 3e-10
TF1A_MOUSE (Q64127) Transcription intermediary factor 1-alpha (T... 65 4e-10
BA2B_CHICK (Q9DE13) Bromodomain adjacent to zinc finger domain 2... 59 4e-08
BA1A_HUMAN (Q9NRL2) Bromodomain adjacent to zinc finger domain p... 58 7e-08
>BRD3_MOUSE (Q8K2F0) Bromodomain-containing protein 3
(Bromodomain-containing FSH-like protein FSRG2)
Length = 726
Score = 140 bits (353), Expect = 9e-33
Identities = 135/480 (28%), Positives = 200/480 (41%), Gaps = 86/480 (17%)
Query: 101 ESGELKSRSSHNGGGSAKKSANKKFSGNKRPFPAEKELKRSKSEVGSAMKACGQILQKLM 160
E + K + GG K K + P A K K ++ ++ C IL++++
Sbjct: 268 EPKQAKVVARRESGGRPIKPPKKDLEDGEVPQHAGK-----KGKLSEHLRHCDSILREML 322
Query: 161 KTK---IGWIFSSPVDPVALNLHDYFDIIKHPMDLGTVKSKLAKNAYSTPAEFADDVKLT 217
K W F PVD AL LHDY DIIKHPMDL TVK K+ Y FA D++L
Sbjct: 323 SKKHAAYAWPFYKPVDAEALELHDYHDIIKHPMDLSTVKRKMDSREYPDAQGFAADIRLM 382
Query: 218 FKNALTYNPKGHDVNTAAMQLLEKFEELY-----------------RPIQEKFDEKSFDD 260
F N YNP H+V A +L + FE + PI K E S
Sbjct: 383 FSNCYKYNPPDHEVVAMARKLQDVFEMRFAKMPDEPMEAPALPAPTAPIVSKGAESSRSS 442
Query: 261 ELQASSWNHVEPERER--------ERVKKKDNPI------PIPPPVAKRQELLPEP---- 302
E +S + E ER E++K + P+ P K+++ E
Sbjct: 443 EESSSDSGSSDSEEERATRLAELQEQLKAVHEQLAALSQAPVNKPKKKKEKKEKEKKKKD 502
Query: 303 ----------ASTSNQPSTSNPPPLAQSPVRTPSPTR-----ALPVKPLKQPKPKAR--- 344
+ S + + P A+ + +PT+ + LK+ +A
Sbjct: 503 KDKDKEKEKHKAKSEEEKKAKAAPAAKQAQQKKAPTKKANSTTTASRQLKKGGKQASASY 562
Query: 345 DPNKRE----MNVEEKHKLGLGLQILPPEKMEQVVQIIRKRNGHL-EQDGDEIELDMEAV 399
D + E M+ +EK +L L + LP EK+ +VV II+ R L + + DEIE+D E +
Sbjct: 563 DSEEEEEGLPMSYDEKRQLSLDINRLPGEKLGRVVHIIQSREPSLRDSNPDEIEIDFETL 622
Query: 400 DTETLWELDRLVTNWKKMVSKIKRQALMDNNNVPSNKGNGELPDREKVDATPPSEGKKQK 459
TL EL+R V K + K +R+ L + + K EL +K + +K
Sbjct: 623 KPTTLRELERYV---KSCLQKKQRKPLSTSGKKQAAKSKEELAQEKKKEL--------EK 671
Query: 460 KIDTVDEDVDIGDDMPANDFPPVEIEKDKDM-GGTGGRASSSSSGSSSSGSGDSSSSETS 518
++ V + N P + EK G R SSSSS S+S S SSS++S
Sbjct: 672 RLQDVSGQL--------NSKKPTKKEKSGSAPSGGPSRLSSSSSSESASSSSSGSSSDSS 723
Score = 80.9 bits (198), Expect = 8e-15
Identities = 59/196 (30%), Positives = 86/196 (43%), Gaps = 11/196 (5%)
Query: 155 ILQKLMKTKIGWIFSSPVDPVALNLHDYFDIIKHPMDLGTVKSKLAKNAYSTPAEFADDV 214
+++ L K + W F PVD + LNL DY IIK+PMD+GT+K +L N Y + +E D
Sbjct: 45 VVKTLWKHQFAWPFYQPVDAIKLNLPDYHKIIKNPMDMGTIKKRLENNYYWSASECMQDF 104
Query: 215 KLTFKNALTYNPKGHDVNTAAMQLLEK--FEELYRPIQEKFD-----EKSFDDELQASSW 267
F N YN D+ A Q LEK +++ + QE+ + K + A +
Sbjct: 105 NTMFTNCYIYNKPTDDIVLMA-QALEKIFLQKVAQMPQEEVELLPPAPKGKGRKPAAGAQ 163
Query: 268 NHVEPERERERVKKKDNPIPIPPPVAKRQELL---PEPASTSNQPSTSNPPPLAQSPVRT 324
N + P PP + ++ P P T+N S PPP A P T
Sbjct: 164 NAGSQQVAAVSSVSPATPFQNIPPTVSQTPVIAATPVPTITANVTSVPVPPPAAPPPPAT 223
Query: 325 PSPTRALPVKPLKQPK 340
P P P+ + K
Sbjct: 224 PIVPVVPPTPPVVKKK 239
>BRD3_HUMAN (Q15059) Bromodomain-containing protein 3 (RING3-like
protein)
Length = 726
Score = 136 bits (342), Expect = 2e-31
Identities = 128/474 (27%), Positives = 190/474 (40%), Gaps = 81/474 (17%)
Query: 104 ELKSRSSHNGGGSAKKSANKKFSGNKRPFPAEKELKRSKSEVGSAMKACGQILQKLMKTK 163
+ K + GG K K + P A K K ++ ++ C IL++++ K
Sbjct: 272 QAKVVARRESGGRPIKPPKKDLEDGEVPQHAGK-----KGKLSEHLRYCDSILREMLSKK 326
Query: 164 ---IGWIFSSPVDPVALNLHDYFDIIKHPMDLGTVKSKLAKNAYSTPAEFADDVKLTFKN 220
W F PVD AL LHDY DIIKHPMDL TVK K+ Y FA DV+L F N
Sbjct: 327 HAAYAWPFYKPVDAEALELHDYHDIIKHPMDLSTVKRKMDGREYPDAQGFAADVRLMFSN 386
Query: 221 ALTYNPKGHDVNTAAMQLLEKFEELY-----------------RPIQEKFDEKSFDDELQ 263
YNP H+V A +L + FE + P+ K E S E
Sbjct: 387 CYKYNPPDHEVVAMARKLQDVFEMRFAKMPDEPVEAPALPAPAAPMVSKGAESSRSSEES 446
Query: 264 ASSWNHVEPERER--------ERVKKKDNPI------PIPPPVAKRQELLPEPASTSNQP 309
+S + E ER E++K + P+ P K+++ E +
Sbjct: 447 SSDSGSSDSEEERATRLAELQEQLKAVHEQLAALSQAPVNKPKKKKEKKEKEKKKKDKEK 506
Query: 310 STSNPPPLAQSPVRTPSPTRALPVKPLKQPKPKAR--------------------DPNKR 349
A+ + A + K P KA D +
Sbjct: 507 EKEKHKVKAEEEKKAKVAPPAKQAQQKKAPAKKANSTTTAGRQLKKGGKQASASYDSEEE 566
Query: 350 E----MNVEEKHKLGLGLQILPPEKMEQVVQIIRKRNGHL-EQDGDEIELDMEAVDTETL 404
E M+ +EK +L L + LP EK+ +VV II+ R L + + DEIE+D E + TL
Sbjct: 567 EEGLPMSYDEKRQLSLDINRLPGEKLGRVVHIIQSREPSLRDSNPDEIEIDFETLKPTTL 626
Query: 405 WELDRLVTNWKKMVSKIKRQALMDNNNVPSNKGNGELPDREKVDATPPSEGKKQKKIDTV 464
EL+R V K + K +R+ + + K EL +K + +K++
Sbjct: 627 RELERYV---KSCLQKKQRKPFSASGKKQAAKSKEELAQEKKKEL--------EKRLQ-- 673
Query: 465 DEDVDIGDDMPANDFPPVEIEKDKDMGGTGGRASSSSSGSSSSGSGDSSSSETS 518
D+ + ++ P + + G R SSSSS S S S SSS++S
Sbjct: 674 ----DVSGQLSSSKKPARKEKPGSAPSGGPSRLSSSSSSESGSSSSSGSSSDSS 723
Score = 76.3 bits (186), Expect = 2e-13
Identities = 62/201 (30%), Positives = 87/201 (42%), Gaps = 35/201 (17%)
Query: 155 ILQKLMKTKIGWIFSSPVDPVALNLHDYFDIIKHPMDLGTVKSKLAKNAYSTPAEFADDV 214
+++ L K + W F PVD + LNL DY IIK+PMD+GT+K +L N Y + +E D
Sbjct: 46 VVKTLWKHQFAWPFYQPVDAIKLNLPDYHKIIKNPMDMGTIKKRLENNYYWSASECMQDF 105
Query: 215 KLTFKNALTYNPKGHDVNTAAMQLLEKFEELYRPIQEKFDEKSFDDELQASSWNHVE--P 272
F N YN D+ A L EK F ++ VE P
Sbjct: 106 NTMFTNCYIYNKPTDDIVLMAQAL----------------EKIFLQKVAQMPQEEVELLP 149
Query: 273 ERERERVKKKDNPIPIPPPVAKRQELLPEPASTSNQPST---SNPPPLAQSPV--RTPSP 327
+ + +K P A+ A +S P+T S PP ++Q+PV TP P
Sbjct: 150 PAPKGKGRK-------PAAGAQSAGTQQVAAVSSVSPATPFQSVPPTVSQTPVIAATPVP 202
Query: 328 T-----RALPVKPLKQPKPKA 343
T ++PV P P P A
Sbjct: 203 TITANVTSVPVPPAAAPPPPA 223
>BRD4_HUMAN (O60885) Bromodomain-containing protein 4 (HUNK1
protein)
Length = 1362
Score = 127 bits (319), Expect = 8e-29
Identities = 118/437 (27%), Positives = 164/437 (37%), Gaps = 123/437 (28%)
Query: 143 SEVGSAMKACGQILQKLMKTK---IGWIFSSPVDPVALNLHDYFDIIKHPMDLGTVKSKL 199
S+V +K C IL+++ K W F PVD AL LHDY DIIKHPMD+ T+KSKL
Sbjct: 348 SKVSEQLKCCSGILKEMFAKKHAAYAWPFYKPVDVEALGLHDYCDIIKHPMDMSTIKSKL 407
Query: 200 AKNAYSTPAEFADDVKLTFKNALTYNPKGHDVNTAAMQLLEKFEELYRPIQEKFDE---- 255
Y EF DV+L F N YNP H+V A +L + FE + + ++ +E
Sbjct: 408 EAREYRDAQEFGADVRLMFSNCYKYNPPDHEVVAMARKLQDVFEMRFAKMPDEPEEPVVA 467
Query: 256 ------------------------------KSFDDELQASSWNHVE-------------- 271
S DD + + E
Sbjct: 468 VSSPAVPPPTKVVAPPSSSDSSSDSSSDSDSSTDDSEEERAQRLAELQEQLKAVHEQLAA 527
Query: 272 ---PERERERVKKKDNPIPIPPPVAKRQELLPEPASTSNQPSTSNPPPLA----QSPVRT 324
P++ + + K+KD K + E + + PPP S
Sbjct: 528 LSQPQQNKPKKKEKDK-----KEKKKEKHKRKEEVEENKKSKAKEPPPKKTKKNNSSNSN 582
Query: 325 PSPTRALPVKPLKQPKPKARDPNK-REMNVEEKHKLGLGLQILPPEKMEQVVQIIRKRNG 383
S P+K P ++ + +K + M+ EEK +L L + LP EK+ +VV II+ R
Sbjct: 583 VSKKEPAPMKSKPPPTYESEEEDKCKPMSYEEKRQLSLDINKLPGEKLGRVVHIIQSREP 642
Query: 384 HLEQDG-DEIELDMEAVDTETLWELDRLVTNWKKMVSKIKRQALMDNNNVPSNKGNGELP 442
L+ DEIE+D E + TL EL+R VT+ + K P
Sbjct: 643 SLKNSNPDEIEIDFETLKPSTLRELERYVTSCLRKKRK---------------------P 681
Query: 443 DREKVDATPPSEGKKQKKIDTVDEDVDIGDDMPANDFPPVEIEKDKDMGGTGGRASSSSS 502
EKVD S K G +SS S
Sbjct: 682 QAEKVDVIAGSSKMK-------------------------------------GFSSSESE 704
Query: 503 GSSSSGSGDSSSSETSI 519
SS S S DS SET +
Sbjct: 705 SSSESSSSDSEDSETEM 721
Score = 85.9 bits (211), Expect = 3e-16
Identities = 67/222 (30%), Positives = 94/222 (42%), Gaps = 17/222 (7%)
Query: 131 PFPAEKELKRSKSEVGSAMKACGQILQKLMKTKIGWIFSSPVDPVALNLHDYFDIIKHPM 190
P P + K + +L+ L K + W F PVD V LNL DY+ IIK PM
Sbjct: 46 PPPETSNPNKPKRQTNQLQYLLRVVLKTLWKHQFAWPFQQPVDAVKLNLPDYYKIIKTPM 105
Query: 191 DLGTVKSKLAKNAYSTPAEFADDVKLTFKNALTYNPKGHDVNTAAMQLLEKFEELY-RPI 249
D+GT+K +L N Y E D F N YN G D+ + + E E+L+ + I
Sbjct: 106 DMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIYNKPGDDI----VLMAEALEKLFLQKI 161
Query: 250 QEKFDEKSFDDELQASSWNHVEPERERERVKKKDNPIP-----IPPPVAKRQELLPEPAS 304
E E++ +QA +E K + +P PP + + P P
Sbjct: 162 NELPTEETEIMIVQAKGRGR--GRKETGTAKPGVSTVPNTTQASTPPQTQTPQPNPPPVQ 219
Query: 305 TSNQPSTSNPPPL-AQSPVRTPSPTRAL----PVKPLKQPKP 341
+ P + P L Q+PV T P + L PV P QP P
Sbjct: 220 ATPHPFPAVTPDLIVQTPVMTVVPPQPLQTPPPVPPQPQPPP 261
Score = 31.6 bits (70), Expect = 5.7
Identities = 25/101 (24%), Positives = 39/101 (37%), Gaps = 13/101 (12%)
Query: 254 DEKSFDDELQASSWNHVEPERERER--------VKKKDNPIPIPPPVAKRQELLPEPAST 305
D + + E+ S P RE+++ +++ P+P PP +Q P P
Sbjct: 713 DSEDSETEMAPKSKKKGHPGREQKKHHHHHHQQMQQAPAPVPQQPPPPPQQPPPPPPPQQ 772
Query: 306 SNQPSTSNPPP-----LAQSPVRTPSPTRALPVKPLKQPKP 341
QP PPP A + +P P A V L+ P
Sbjct: 773 QQQPPPPPPPPSMPQQAAPAMKSSPPPFIATQVPVLEPQLP 813
>BRD4_MOUSE (Q9ESU6) Bromodomain-containing protein 4 (Mitotic
chromosome-associated protein) (MCAP)
Length = 1400
Score = 126 bits (317), Expect = 1e-28
Identities = 119/443 (26%), Positives = 169/443 (37%), Gaps = 135/443 (30%)
Query: 143 SEVGSAMKACGQILQKLMKTK---IGWIFSSPVDPVALNLHDYFDIIKHPMDLGTVKSKL 199
S++ +K C IL+++ K W F PVD AL LHDY DIIKHPMD+ T+KSKL
Sbjct: 349 SKISEQLKCCSGILKEMFAKKHAAYAWPFYKPVDVEALGLHDYCDIIKHPMDMSTIKSKL 408
Query: 200 AKNAYSTPAEFADDVKLTFKNALTYNPKGHDVNTAAMQLLEKFEELYRPIQEKFDE---- 255
Y EF DV+L F N YNP H+V A +L + FE + + ++ +E
Sbjct: 409 ESREYRDAQEFGADVRLMFSNCYKYNPPDHEVVAMARKLQDVFEMRFAKMPDEPEEPVVT 468
Query: 256 ------------------------------KSFDDELQASSWNHVE-------------- 271
S DD + + E
Sbjct: 469 VSSPAVPPPTKVVAPPSSSDSSSDSSSDSDSSTDDSEEERAQRLAELQEQLKAVHEQLAA 528
Query: 272 ---PERERERVKKKDNPIPIPPPVAKRQEL----------LPEPASTSNQPSTSNPPPLA 318
P++ + + K+KD K++E+ LP + N S SN
Sbjct: 529 LSQPQQNKPKKKEKDKKEKKKEKHKKKEEVEENKKSKTKELPPKKTKKNNSSNSNVSK-- 586
Query: 319 QSPVRTPSPTRALPVKPLKQPKPKARDPNK-REMNVEEKHKLGLGLQILPPEKMEQVVQI 377
+ P PT+ P P ++ + +K + M+ EEK +L L + LP EK+ +VV I
Sbjct: 587 ----KEPVPTKTKP-----PPTYESEEEDKCKPMSYEEKRQLSLDINKLPGEKLGRVVHI 637
Query: 378 IRKRNGHLEQDG-DEIELDMEAVDTETLWELDRLVTNWKKMVSKIKRQALMDNNNVPSNK 436
I+ R L+ DEIE+D E + TL EL+R VT+ + K
Sbjct: 638 IQSREPSLKNSNPDEIEIDFETLKPSTLRELERYVTSCLRKKRK---------------- 681
Query: 437 GNGELPDREKVDATPPSEGKKQKKIDTVDEDVDIGDDMPANDFPPVEIEKDKDMGGTGGR 496
P EKVD S K G
Sbjct: 682 -----PQAEKVDVIAGSSKMK-------------------------------------GF 699
Query: 497 ASSSSSGSSSSGSGDSSSSETSI 519
+SS S +S S S DS SET +
Sbjct: 700 SSSESESTSESSSSDSEDSETEM 722
Score = 83.6 bits (205), Expect = 1e-15
Identities = 66/224 (29%), Positives = 93/224 (41%), Gaps = 19/224 (8%)
Query: 131 PFPAEKELKRSKSEVGSAMKACGQILQKLMKTKIGWIFSSPVDPVALNLHDYFDIIKHPM 190
P P + K + +L+ L K + W F PVD V LNL DY+ IIK PM
Sbjct: 46 PPPETSNPNKPKRQTNQLQYLLRVVLKTLWKHQFAWPFQQPVDAVKLNLPDYYKIIKTPM 105
Query: 191 DLGTVKSKLAKNAYSTPAEFADDVKLTFKNALTYNPKGHDVNTAAMQLLEKFEELY-RPI 249
D+GT+K +L N Y E D F N YN G D+ + + E E+L+ + I
Sbjct: 106 DMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIYNKPGDDI----VLMAEALEKLFLQKI 161
Query: 250 QEKFDEKSFDDELQASSWNHVEPERERERVKKKDNPIP------IPPPVAKRQELLPEPA 303
E E++ +QA +E K + +P P Q+ P P
Sbjct: 162 NELPTEETEIMIVQAKGRGR--GRKETGAAKPGVSTVPNTTQASTSPQTQTPQQNPPPPV 219
Query: 304 STSNQPSTSNPPPL-AQSPVRTPSPTRALPVKPLKQPKPKARDP 346
+ P + P L AQ PV T +P +PL+ P P P
Sbjct: 220 QATTHPFPAVTPDLIAQPPVMT-----MVPPQPLQTPSPVPPQP 258
Score = 33.1 bits (74), Expect = 2.0
Identities = 20/85 (23%), Positives = 38/85 (44%), Gaps = 7/85 (8%)
Query: 272 PERERERVKKKDNPIPIP---PPVAKRQELLPEPASTSNQPSTSN----PPPLAQSPVRT 324
P ++++++ + P P P PP ++ + P P + P +++ PPP Q P
Sbjct: 966 PSVQQQQLQPQPPPPPPPQPQPPPQQQHQPPPRPVHLPSMPFSAHIQQPPPPPGQQPTHP 1025
Query: 325 PSPTRALPVKPLKQPKPKARDPNKR 349
P + P +P K + P+ R
Sbjct: 1026 PPGQQPPPPQPAKPQQVIQHHPSPR 1050
>BDF1_YEAST (P35817) BDF1 protein
Length = 686
Score = 115 bits (287), Expect = 4e-25
Identities = 109/429 (25%), Positives = 177/429 (40%), Gaps = 30/429 (6%)
Query: 101 ESGELKSRSSHNGGGSAKKSANKKFSGNKRPFPAEKELKRSKSEVGSAMKACGQILQKLM 160
E + R + G K++ + S K +P E + +SK + AMK C +L++LM
Sbjct: 273 EDAPIVIRRAQTHNGRPKRTIHPPKS--KDIYPYESKKPKSK-RLQQAMKFCQSVLKELM 329
Query: 161 KTK---IGWIFSSPVDPVALNLHDYFDIIKHPMDLGTVKSKLAKNAYSTPAEFADDVKLT 217
K + F PVDPV++NL YFD +K PMDLGT+ KL Y T +F DV+L
Sbjct: 330 AKKHASYNYPFLEPVDPVSMNLPTYFDYVKEPMDLGTIAKKLNDWQYQTMEDFERDVRLV 389
Query: 218 FKNALTYNPKGHDVNTAAMQLLEKFEELYRPIQEKFDEKSFDDELQASSWNHVEPERERE 277
FKN T+NP G VN +L E F + D S +D ++ E E
Sbjct: 390 FKNCYTFNPDGTIVNMMGHRLEEVFNSKWADRPNLDDYDSDEDSRTQGDYDDYESEYSES 449
Query: 278 RVKKKDNPIPIPPPVAKRQELLPEPASTSNQPSTSNPPPL-AQSPVRTPSPTRALPVK-- 334
+ D I P + +E L Q + + + S R K
Sbjct: 450 DI---DETIITNPAIQYLEEQLARMKVELQQLKKQELEKIRKERRLARGSKKRGKRSKGR 506
Query: 335 -PLKQPKPKARDPNKREMNV----EEKHKLGLGLQILPPEKMEQVVQIIRKRNGHLEQDG 389
K K R K ++ + K + + LP K+E+ + II+K ++ +D
Sbjct: 507 SGSKNASSKGRRDKKNKLKTVVTYDMKRIITERINDLPTSKLERAIDIIKKSMPNISED- 565
Query: 390 DEIELDMEAVDTETLWELDRLVTNWKKMVSKIKRQALMDNNNVPSNKGNGELPDREKVDA 449
DE+ELD++ +D T+ L + S +N + G R+
Sbjct: 566 DEVELDLDTLDNHTILTLYNTFFRQYESSSGA-------SNGLDGTSG----VTRDASSL 614
Query: 450 TPPSEGKKQKKIDTVDEDVDIGD-DMPANDFPPVEIEKDKDMGGTGGRASSSSSGSSSSG 508
+P S G ++++ + ++ + N ++ G+ G+ S++ SS
Sbjct: 615 SPTSAGSRKRRSKALSQEEQSRQIEKIKNKLAILDSASPLSQNGSPGQIQSAAHNGFSSS 674
Query: 509 SGDSSSSET 517
S D SSE+
Sbjct: 675 SDDDVSSES 683
Score = 60.5 bits (145), Expect = 1e-08
Identities = 28/77 (36%), Positives = 42/77 (54%)
Query: 168 FSSPVDPVALNLHDYFDIIKHPMDLGTVKSKLAKNAYSTPAEFADDVKLTFKNALTYNPK 227
F PVDPV L++ YF+ IK PMDL T++ KL AY P + +D L N++ +N
Sbjct: 173 FLQPVDPVKLDIPFYFNYIKRPMDLSTIERKLNVGAYEVPEQITEDFNLMVNNSIKFNGP 232
Query: 228 GHDVNTAAMQLLEKFEE 244
++ A + FE+
Sbjct: 233 NAGISQMARNIQASFEK 249
>YCK2_SCHPO (Q9Y7N0) Hypothetical bromodomain protein C1450.02
Length = 578
Score = 103 bits (257), Expect = 1e-21
Identities = 85/310 (27%), Positives = 137/310 (43%), Gaps = 31/310 (10%)
Query: 108 RSSHNGGGSAKKSANKKFSGNKRPFPAE-KELKRSKSEVGSAMKACGQILQKLMKTK--- 163
R+ N S+ ++ + K PA E K + + S M+ C +L++L K +
Sbjct: 215 RTRRNSSVSSTSASVAASTAPKAASPAVLPEGKPRRRKNNSQMRFCSTVLKELYKRQYES 274
Query: 164 IGWIFSSPVDPVALNLHDYFDIIKHPMDLGTVKSKLAKNAYSTPAEFADDVKLTFKNALT 223
+ F PVDPVA + DYFD+IK PMDL T++SKL KN YST EF D+ L F N T
Sbjct: 275 FAFPFYQPVDPVACDCPDYFDVIKEPMDLSTIQSKLNKNEYSTLEEFESDILLMFNNCFT 334
Query: 224 YNPKGHDVNTAAMQLLEKFEELYRPIQEKFDEKSFDDELQASSWNHVEPERERERVKKKD 283
YNP G V+ QL F+E + + KFD+ + + +A + + E E + ++
Sbjct: 335 YNPPGTPVHVMGRQLENVFKEKWE-ARPKFDDATLVKQQEAETDALFDNGEEEEALMSEE 393
Query: 284 NPIPIPPPVAKRQELLPEPASTSNQPSTSNPPPLAQSPVRTPSPTRALPVKPLKQPKPKA 343
+Q + + + + N + KP+
Sbjct: 394 EINGAKFAAVDKQISMLQDTLEAMKAKKMN-----------------------RMRKPRR 430
Query: 344 RDPNKR--EMNVEEKHKLGLGLQILPPEKMEQVVQIIRKRNGHLEQDGDEIELDMEAVDT 401
RD K + +++L L E++ V +I+R+ L +D DEIE+D+ +
Sbjct: 431 RDLTKEYGPITYAMQNELAERCNYLSAEQLSNVAEILREEMPWL-RDTDEIEIDVGNMKP 489
Query: 402 ETLWELDRLV 411
E + R V
Sbjct: 490 EVFHRIYRYV 499
Score = 88.2 bits (217), Expect = 5e-17
Identities = 70/251 (27%), Positives = 103/251 (40%), Gaps = 37/251 (14%)
Query: 101 ESGELKSRSSHNGGGSAK--KSANKKFSGNKRPFPAEKELKRSKSEVGSAMKACGQILQK 158
E+ E SR + G + K K+ K P P K++ R K C I+++
Sbjct: 41 ENEESLSRKRDSSGATVGDLKQEEKESMPKKEPEPTVKKI-RGSGMPPPQQKYCLAIVRQ 99
Query: 159 LMKTKIGWIFSSPVDPVALNLHDYFDIIKHPMDLGTVKSKLAKNAYSTPAEFADDVKLTF 218
L +TK F PVDP+ N+ DY I+K+PMDLGT++ KL YS P EF DD+ L F
Sbjct: 100 LKRTKNSAPFKVPVDPIKQNIPDYPTIVKNPMDLGTIEKKLTSYEYSVPQEFIDDMNLMF 159
Query: 219 KNALTYNPKGHDVNTAAMQLLEKFEELYRPIQEKFDEKSFDDELQASSWNHVEPERERER 278
N YN V + L E F ER+ ++
Sbjct: 160 SNCFLYNGTESPVGSMGKALQEVF------------------------------ERQLKQ 189
Query: 279 VKKKDNPIPIPPPVAKRQELLPEPASTSNQPSTSNPPPLAQSPVRTPSPTRALPVKPLKQ 338
+ + P P +K++ P T S S+ + S + +P A P L +
Sbjct: 190 LPDAEQPAAAPVKKSKQKSASTAPPRTRRNSSVSS---TSASVAASTAPKAASPA-VLPE 245
Query: 339 PKPKARDPNKR 349
KP+ R N +
Sbjct: 246 GKPRRRKNNSQ 256
>BRD2_HUMAN (P25440) Bromodomain-containing protein 2 (RING3
protein) (O27.1.1)
Length = 801
Score = 103 bits (256), Expect = 2e-21
Identities = 72/250 (28%), Positives = 104/250 (40%), Gaps = 39/250 (15%)
Query: 131 PFPAEKELKRSKSEVGSAMKACGQILQKLMKTK---IGWIFSSPVDPVALNLHDYFDIIK 187
P ++ K ++ +K C IL++L+ K W F PVD AL LHDY DIIK
Sbjct: 332 PDSQQQHQSSKKGKLSEQLKHCNGILKELLSKKHAAYAWPFYKPVDASALGLHDYHDIIK 391
Query: 188 HPMDLGTVKSKLAKNAYSTPAEFADDVKLTFKNALTYNPKGHDVNTAAMQLLEKFEELYR 247
HPMDL TVK K+ Y EFA DV+L F N YNP HDV A +L + FE Y
Sbjct: 392 HPMDLSTVKRKMENRDYRDAQEFAADVRLMFSNCYKYNPPDHDVVAMARKLQDVFEFRYA 451
Query: 248 PIQE-------------------KFDEKSFDDELQASSWNHVEPERERERVKKKDNPIPI 288
+ + K +S +E + S + E E + E +++++
Sbjct: 452 KMPDEPLEPGPLPVSTAMPPGLAKSSSESSSEESSSESSSEEEEEEDEEDEEEEES---- 507
Query: 289 PPPVAKRQELLPEPASTSNQPSTSNPPPLAQSPVRTPSPTRALPVKPLKQPKPKARDPNK 348
+S S + L + AL P+ +PK K K
Sbjct: 508 -------------ESSDSEEERAHRLAELQEQLRAVHEQLAALSQGPISKPKRKREKKEK 554
Query: 349 REMNVEEKHK 358
++ EKH+
Sbjct: 555 KKKRKAEKHR 564
Score = 68.2 bits (165), Expect = 6e-11
Identities = 78/280 (27%), Positives = 103/280 (35%), Gaps = 51/280 (18%)
Query: 131 PFPAEKELKRSKSEVGSAMKACGQILQK-LMKTKIGWIFSSPVDPVALNLHDYFDIIKHP 189
P P E + V + ++ +++ K L K + W F PVD V L L DY IIK P
Sbjct: 61 PPPPEVSNPKKPGRVTNQLQYLHKVVMKALWKHQFAWPFRQPVDAVKLGLPDYHKIIKQP 120
Query: 190 MDLGTVKSKLAKNAYSTPAEFADDVKLTFKNALTYNPKGHDVNTAAMQLLEKF------- 242
MD+GT+K +L N Y +E D F N YN D+ A Q LEK
Sbjct: 121 MDMGTIKRRLENNYYWAASECMQDFNTMFTNCYIYNKPTDDIVLMA-QTLEKIFLQKVAS 179
Query: 243 -----EELYRPIQEKFDEK------------SFDDELQASSWNH----VEPERERERVKK 281
+EL I + +K S SS +H P V
Sbjct: 180 MPQEEQELVVTIPKNSHKKGAKLAALQGSVTSAHQVPAVSSVSHTALYTPPPEIPTTVLN 239
Query: 282 KDNPIPIPPPVAKR-----QELLPEPASTSNQPSTSNPPPLAQSPVRTPSPTRAL----P 332
+P I P+ K LL A+ QP ++ TP+PT L P
Sbjct: 240 IPHPSVISSPLLKSLHSAGPPLLAVTAAPPAQPLAKKKGVKRKADTTTPTPTAILAPGSP 299
Query: 333 VKPLKQPKPKAR--DPNKREMNVEEKHKLGLGLQILPPEK 370
P +PKA P +RE G I PP K
Sbjct: 300 ASPPGSLEPKAARLPPMRRES----------GRPIKPPRK 329
Score = 62.8 bits (151), Expect = 2e-09
Identities = 75/296 (25%), Positives = 119/296 (39%), Gaps = 34/296 (11%)
Query: 243 EELYRPIQEKFDEKSFDDELQASSWNHV-EPERERERVKKKDN----------------- 284
E +R + + ++ ++L A S + +P+R+RE+ +KK
Sbjct: 515 ERAHRLAELQEQLRAVHEQLAALSQGPISKPKRKREKKEKKKKRKAEKHRGRAGADEDDK 574
Query: 285 -PIPIPPPVAKRQELLPEPASTSNQPSTSNPPPLAQSPVRTPSPTRALPVKPLKQPKPKA 343
P PP K+ + S S P S + P L
Sbjct: 575 GPRAPRPPQPKKSKKASGSGGGSAALGPSGFGPSGGSGTKLPKKATKTAPPALPTGYDSE 634
Query: 344 RDPNKREMNVEEKHKLGLGLQILPPEKMEQVVQIIRKRNGHL-EQDGDEIELDMEAVDTE 402
+ R M+ +EK +L L + LP EK+ +VV II+ R L + + +EIE+D E +
Sbjct: 635 EEEESRPMSYDEKRQLSLDINKLPGEKLGRVVHIIQAREPSLRDSNPEEIEIDFETLKPS 694
Query: 403 TLWELDRLVTNWKKMVSKIKRQALMDNNNVPSNKGNGELPDREKVDATPPSEGKKQKKID 462
TL EL+R V + + K+ P K EL +K + +K++
Sbjct: 695 TLRELERYVLSCLR-----KKPRKPYTIKKPVGKTKEELALEKKREL--------EKRLQ 741
Query: 463 TVDEDVDIGDDMPANDFPPVEIEKDKDMGGTGGRASSSSSGSSSSGSGDSSSSETS 518
V ++ P E + + + ASSSSS SSSS S SSSS+TS
Sbjct: 742 DVSGQLNSTKKPPKKANEKTESSSAQQVAVSRLSASSSSSDSSSS-SSSSSSSDTS 796
>FSH_DROME (P13709) Female sterile homeotic protein (Fragile-chorion
membrane protein)
Length = 2038
Score = 99.4 bits (246), Expect = 2e-20
Identities = 51/116 (43%), Positives = 67/116 (56%), Gaps = 3/116 (2%)
Query: 140 RSKSEVGSAMKACGQILQKLMKTK---IGWIFSSPVDPVALNLHDYFDIIKHPMDLGTVK 196
++K ++ A+K+C +IL++L K W F PVD L LHDY DIIK PMDLGTVK
Sbjct: 472 KNKEKLSDALKSCNEILKELFSKKHSGYAWPFYKPVDAEMLGLHDYHDIIKKPMDLGTVK 531
Query: 197 SKLAKNAYSTPAEFADDVKLTFKNALTYNPKGHDVNTAAMQLLEKFEELYRPIQEK 252
K+ Y + EFA DV+L F N YNP HDV +L + FE Y I ++
Sbjct: 532 RKMDNREYKSAPEFAADVRLIFTNCYKYNPPDHDVVAMGRKLQDVFEMRYANIPDE 587
Score = 72.0 bits (175), Expect = 4e-12
Identities = 48/160 (30%), Positives = 65/160 (40%), Gaps = 16/160 (10%)
Query: 155 ILQKLMKTKIGWIFSSPVDPVALNLHDYFDIIKHPMDLGTVKSKLAKNAYSTPAEFADDV 214
+++ + K W F PVD LNL DY IIK PMD+GT+K +L N Y + E D
Sbjct: 46 VMKVIWKHHFSWPFQQPVDAKKLNLPDYHKIIKQPMDMGTIKKRLENNYYWSAKETIQDF 105
Query: 215 KLTFKNALTYNPKGHDVNTAAMQLLEKFEELYRPIQEKFDEKSFDDELQASSWNHVEPER 274
F N YN G DV A L EK F ++++ +E E
Sbjct: 106 NTMFNNCYVYNKPGEDVVVMAQTL----------------EKVFLQKIESMPKEELELEP 149
Query: 275 ERERVKKKDNPIPIPPPVAKRQELLPEPASTSNQPSTSNP 314
+ KK P P + + TS+ TS P
Sbjct: 150 VTAKGGKKKQRAPATPKSSSGGAGASTGSGTSSAAVTSGP 189
Score = 60.5 bits (145), Expect = 1e-08
Identities = 56/172 (32%), Positives = 83/172 (47%), Gaps = 22/172 (12%)
Query: 349 REMNVEEKHKLGLGLQILPPEKMEQVVQIIRKRNGHL-EQDGDEIELDMEAVDTETLWEL 407
+ M+ +EK +L L + LP +K+ +VV II+ R L + + DEIE+D E + TL EL
Sbjct: 950 KPMSYDEKRQLSLDINKLPGDKLGRVVHIIQNREPSLRDSNPDEIEIDFETLKPSTLREL 1009
Query: 408 DRLVTNWKKMVSKIKRQALMDNNNVPSNKGNGELPDR-EKVDATPPSEGKKQKKIDTVDE 466
+ V + + + K + + K EL R + V + K KK ++
Sbjct: 1010 ESYVASCLRKKTHKKPSGKSKDEQMAEKKQ--ELEKRLQDVTGQLGASKKTAKKDESASS 1067
Query: 467 DVDIGDDMPANDFPPVEIEKDKDMGGTGGRASSSSSGSSSSGSGDSSSSETS 518
V+ PAN PV +SSSSS SSSS S DSSSS++S
Sbjct: 1068 KVEAVQ--PAN---PVS-------------SSSSSSDSSSSSSSDSSSSDSS 1101
>YK82_SCHPO (Q9HGP4) Hypothetical bromodomain protein C631.02
Length = 727
Score = 91.3 bits (225), Expect = 6e-18
Identities = 104/466 (22%), Positives = 191/466 (40%), Gaps = 81/466 (17%)
Query: 70 NVSSYSKSELNELRNCFVTELEQIRQLQTRIESGELKSRSSHNGGGSAKKSANKKFSGNK 129
N+ + + +L +L + +VT + +S ++ GG ++ A + +
Sbjct: 323 NLQATFERQLKQLPSAYVTSYSR--------PGRRPRSMTAPKGGARTRRQAAMYSNSSS 374
Query: 130 RPFPAEKELKRSKSEVGSAMKACGQILQKLMKTK---IGWIFSSPVDPVALNLHDYFDII 186
+LK + + + MK C +L++L+K + + F PV+P A DYF +I
Sbjct: 375 GIRETMYDLKPHRRKDAAEMKFCQSVLKELLKKQHEAYAYPFYKPVNPTACGCPDYFKVI 434
Query: 187 KHPMDLGTVKSKLAKNAYSTPAEFADDVKLTFKNALTYNPKGHDVNTAAMQLLEKFEELY 246
KHPMDLGT+++KL N Y++ F D+ L FKN +N G V+ +L F++L+
Sbjct: 435 KHPMDLGTMQNKLNHNEYASMKAFEADMVLMFKNCYKFNSAGTPVHLMGKKLESIFQKLW 494
Query: 247 RPIQEKFDEKSF-------------DDELQASSWNHVEPERER-ERVKKKDNPIPIPPPV 292
+ FD +++ D+E+ S +E + E E V ++ +
Sbjct: 495 AN-KPDFDSETYMGMSSVNTDYYYGDNEVFDSGDEFLEDDGEEFEAVNRQ---------I 544
Query: 293 AKRQELLPEPASTSNQPSTSNPPPLAQSPVRTPSPTRALPVKPLKQPKPKARDPNKREMN 352
K Q L S + S S R+ S + ++ + P +
Sbjct: 545 HKLQSTLQAMKSRARSSSVSR---------RSRSRSLSVDIYP--------------PIT 581
Query: 353 VEEKHKLGLGLQILPPEKMEQVVQIIRKRNGHLEQDGDEIELDMEAVDTETLWELDRLVT 412
E +++L L +++ V +I+R HL ++ DEIE+D+ A+ + +++ V
Sbjct: 582 YEMQNELAEQCNYLSADQLSHVAEILRAALPHL-RNTDEIEIDVSAMPPDVFYKVYYYVC 640
Query: 413 NWKKMVSKIKRQALMDNNNVPSNKGNGELPDREKVDATPPSEGKKQKKIDTVDEDVDIGD 472
+I +AL ++ K G SE ++ +KI + +D
Sbjct: 641 KG----DEIGAEALATASHTHQEKKKGR----------ALSETEQAEKIRQLRAQLD--- 683
Query: 473 DMPANDFPPVEIEKDKDMGGTGGRASSSSSGSSSSGSGDSSSSETS 518
F + K+ G + S SS D SSE+S
Sbjct: 684 -----RFSGIAQNKNTVTGNIAAYNTKSLGSDDSSSEDDGESSESS 724
Score = 72.8 bits (177), Expect = 2e-12
Identities = 45/165 (27%), Positives = 79/165 (47%), Gaps = 9/165 (5%)
Query: 98 TRIESGELKSRSSHNGGGSAKKSANKKFSGNKRPF--PAEKELKRSKSE-------VGSA 148
T S ++KS +S + SA ++ + +G+ + P ++ +K+ +++
Sbjct: 175 TNDASNKIKSEASESASPSALQALDSTAAGSSKEHSSPHDETVKKEENDKDQYPPMTKEQ 234
Query: 149 MKACGQILQKLMKTKIGWIFSSPVDPVALNLHDYFDIIKHPMDLGTVKSKLAKNAYSTPA 208
K +L++L + + F +PVDPV N+ DY IIK+P+DLGT++ K + YS+
Sbjct: 235 HKYIHAMLRQLRRGRDSIPFRAPVDPVKQNIPDYPTIIKNPIDLGTMQKKFSSGVYSSAQ 294
Query: 209 EFADDVKLTFKNALTYNPKGHDVNTAAMQLLEKFEELYRPIQEKF 253
F DD+ L F N YN V L FE + + +
Sbjct: 295 HFIDDMNLMFSNCFLYNGTESPVGVMGKNLQATFERQLKQLPSAY 339
>CBP_MOUSE (P45481) CREB-binding protein (EC 2.3.1.48)
Length = 2441
Score = 78.2 bits (191), Expect = 5e-14
Identities = 38/84 (45%), Positives = 49/84 (58%)
Query: 168 FSSPVDPVALNLHDYFDIIKHPMDLGTVKSKLAKNAYSTPAEFADDVKLTFKNALTYNPK 227
F PVDP L + DYFDI+K+PMDL T+K KL Y P ++ DDV+L F NA YN K
Sbjct: 1112 FRQPVDPQLLGIPDYFDIVKNPMDLSTIKRKLDTGQYQEPWQYVDDVRLMFNNAWLYNRK 1171
Query: 228 GHDVNTAAMQLLEKFEELYRPIQE 251
V +L E FE+ P+ +
Sbjct: 1172 TSRVYKFCSKLAEVFEQEIDPVMQ 1195
>CBP_HUMAN (Q92793) CREB-binding protein (EC 2.3.1.48)
Length = 2442
Score = 76.3 bits (186), Expect = 2e-13
Identities = 38/84 (45%), Positives = 48/84 (56%)
Query: 168 FSSPVDPVALNLHDYFDIIKHPMDLGTVKSKLAKNAYSTPAEFADDVKLTFKNALTYNPK 227
F PVDP L + DYFDI+K+PMDL T+K KL Y P ++ DDV L F NA YN K
Sbjct: 1111 FRQPVDPQLLGIPDYFDIVKNPMDLSTIKRKLDTGQYQEPWQYVDDVWLMFNNAWLYNRK 1170
Query: 228 GHDVNTAAMQLLEKFEELYRPIQE 251
V +L E FE+ P+ +
Sbjct: 1171 TSRVYKFCSKLAEVFEQEIDPVMQ 1194
Score = 32.7 bits (73), Expect = 2.6
Identities = 18/63 (28%), Positives = 27/63 (42%), Gaps = 3/63 (4%)
Query: 284 NPIPIPPPVAKRQELLPEPASTSNQPSTSNPPPLAQSPVRTPSPTRALPVKPLKQPKPKA 343
+P PP +Q P+ T P+ P P++ SP PS R P + KP +
Sbjct: 1884 SPTSAPPGTPTQQPSTPQ---TPQPPAQPQPSPVSMSPAGFPSVARTQPPTTVSTGKPTS 1940
Query: 344 RDP 346
+ P
Sbjct: 1941 QVP 1943
>P300_HUMAN (Q09472) E1A-associated protein p300 (EC 2.3.1.48)
Length = 2414
Score = 74.7 bits (182), Expect = 6e-13
Identities = 37/84 (44%), Positives = 47/84 (55%)
Query: 168 FSSPVDPVALNLHDYFDIIKHPMDLGTVKSKLAKNAYSTPAEFADDVKLTFKNALTYNPK 227
F PVDP L + DYFDI+K PMDL T+K KL Y P ++ DD+ L F NA YN K
Sbjct: 1075 FRQPVDPQLLGIPDYFDIVKSPMDLSTIKRKLDTGQYQEPWQYVDDIWLMFNNAWLYNRK 1134
Query: 228 GHDVNTAAMQLLEKFEELYRPIQE 251
V +L E FE+ P+ +
Sbjct: 1135 TSRVYKYCSKLSEVFEQEIDPVMQ 1158
Score = 30.8 bits (68), Expect = 9.7
Identities = 51/249 (20%), Positives = 84/249 (33%), Gaps = 58/249 (23%)
Query: 268 NHVEPERERERVKKKDNPIPIP-----PPVAKRQELLPEPASTSNQPSTSNPPPLAQSPV 322
+H P ++ P P+P PP + Q L P P T P+T P + S
Sbjct: 843 HHTPPSIGAQQPPATTIPAPVPTPPAMPPGPQSQALHPPPRQTPTPPTTQLPQQVQPSLP 902
Query: 323 RTPSPTRALPVKPLKQPKPKARDPNKREMNVEEKHKLGLGLQILPPEKMEQVVQIIRKRN 382
PS QP+ + R +V + +LPP+
Sbjct: 903 AAPS---------ADQPQQQPRSQQSTAASVPTPN-----APLLPPQPATP--------- 939
Query: 383 GHLEQDGDEIELDMEAVDTETLWELDRLVTNWKKMVSKIKRQALMDNNNVPSNKGNGELP 442
L Q IE + + + E++ K+ ++K +A M E+
Sbjct: 940 --LSQPAVSIEGQVSNPPSTSSTEVNSQAIAEKQPSQEVKMEAKM------------EVD 985
Query: 443 DREKVDATPP--SEGK----KQKKIDTVDEDVDIGDDMPANDFPPVEIEKDKDMGGTGGR 496
E D P SE K K + +T + ++ EI++++D T
Sbjct: 986 QPEPADTQPEDISESKVEDCKMESTETEERSTEL----------KTEIKEEEDQPSTSAT 1035
Query: 497 ASSSSSGSS 505
SS + G S
Sbjct: 1036 QSSPAPGQS 1044
>WDR9_HUMAN (Q9NSI6) WD-repeat protein 9
Length = 2269
Score = 72.4 bits (176), Expect = 3e-12
Identities = 53/197 (26%), Positives = 91/197 (45%), Gaps = 14/197 (7%)
Query: 123 KKFSGNKRPFPAEKELKRSKSEVGSAMKACGQILQKLMKTKIGWIFSSPVDPVALNLHDY 182
K SG +R +K ++ + + K C +++ + + + F PVD V DY
Sbjct: 1293 KTSSGRRRVHDGKKSIRATNYVESNWKKQCKELVNLIFQCEDSEPFRQPVDLV--EYPDY 1350
Query: 183 FDIIKHPMDLGTVKSKLAKNAYSTPAEFADDVKLTFKNALTYNP-KGHDVNTAAMQLLEK 241
DII PMD GTV+ L Y +P EF D++L F NA Y P K + + ++L
Sbjct: 1351 RDIIDTPMDFGTVRETLDAGNYDSPLEFCKDIRLIFSNAKAYTPNKRSKIYSMTLRLSAL 1410
Query: 242 FEELYRPIQEKFD-EKSFDDELQASSWNHVEPERERERVKKKDNPIPI-----PPPVAKR 295
FEE + I F + F+++L+ S + ++R+ K P P + +
Sbjct: 1411 FEEKMKKISSDFKIGQKFNEKLRRS-----QRFKQRQNCKGDSQPNKSIRNLKPKRLKSQ 1465
Query: 296 QELLPEPASTSNQPSTS 312
+++PE + Q ++S
Sbjct: 1466 TKIIPELVGSPTQSTSS 1482
Score = 32.3 bits (72), Expect = 3.3
Identities = 19/86 (22%), Positives = 39/86 (45%), Gaps = 2/86 (2%)
Query: 156 LQKLMKTKIGWIFSSPVDPVALNLHDYFDIIKHPMDLGTVKSKLAKNAYSTPAEFADDVK 215
+ +L+ I F+ PVD Y ++ +P DL T++ +L Y + +V+
Sbjct: 1173 IDQLLNLDIAAAFAGPVD--LCTYPKYCTVVAYPTDLYTIRMRLVNRFYRRLSALVWEVR 1230
Query: 216 LTFKNALTYNPKGHDVNTAAMQLLEK 241
NA T+N + +A ++ ++
Sbjct: 1231 YIEHNARTFNEPESVIARSAKKITDQ 1256
>BA1B_HUMAN (Q9UIG0) Bromodomain adjacent to zinc finger domain
protein 1B (Williams-Beuren syndrome chromosome region 9
protein) (WBRS9) (Williams syndrome transcription factor)
(hWALP2)
Length = 1483
Score = 70.9 bits (172), Expect = 8e-12
Identities = 58/191 (30%), Positives = 88/191 (45%), Gaps = 22/191 (11%)
Query: 109 SSHNGGGSAKKSANKKFSGNKRPFPAEKEL-------KRSKSEVGSAMKACGQILQKLMK 161
++ +G KK + + S K P + E+ KRS ++ C +IL K++K
Sbjct: 1298 AARSGRRPGKKPHSTRRSQPKAPPVDDAEVDELVLQTKRSSRRQSLELQKCEEILHKIVK 1357
Query: 162 TKIGWIFSSPVDPVALNLHDYFDIIKHPMDLGTVKSKLAKNAYSTPAEFADDVKLTFKNA 221
+ W F PV DY+D+I HPMD TV++K + +Y + EF D+K F NA
Sbjct: 1358 YRFSWPFREPV--TRDEAEDYYDVITHPMDFQTVQNKCSCGSYRSVQEFLTDMKQVFTNA 1415
Query: 222 LTYNPKGHDVNTAAMQ-------LLEKFEELYRPIQEKFDEKSFDDELQASSWNHVEPE- 273
YN +G V + ++ LL K + ++ K K F D L A EPE
Sbjct: 1416 EVYNCRGSHVLSCMVKTEQCLVALLHKHLPGHPYVRRK--RKKFPDRL-AEDEGDSEPEA 1472
Query: 274 --RERERVKKK 282
+ R R +KK
Sbjct: 1473 VGQSRGRRQKK 1483
>BA1B_MOUSE (Q9Z277) Bromodomain adjacent to zinc finger domain
protein 1B (Williams-Beuren syndrome chromosome region 9
protein homolog) (WBRS9)
Length = 1479
Score = 68.6 bits (166), Expect = 4e-11
Identities = 54/202 (26%), Positives = 83/202 (40%), Gaps = 26/202 (12%)
Query: 89 ELEQIRQLQTRIESGELKSRSSHNGGGSAKKSANKKFSGNKRPFPAEKELKRSKSEVGSA 148
E E+ + + L+ R + G S +A K+ PA + + EV
Sbjct: 1267 EEEEEEEEDYEVAGLRLRPRKTIRGKQSVIPAARPGRPPGKKSHPARRSRPKDDPEVDDL 1326
Query: 149 --------------MKACGQILQKLMKTKIGWIFSSPVDPVALNLHDYFDIIKHPMDLGT 194
++ C IL KL+K + W F PV DY+D+I+HPMD T
Sbjct: 1327 VLQTKRISRRQSLELQKCEDILHKLVKYRFSWPFREPV--TRDEAEDYYDVIEHPMDFQT 1384
Query: 195 VKSKLAKNAYSTPAEFADDVKLTFKNALTYNPKGHDV-------NTAAMQLLEKF---EE 244
+++K + Y + EF D+K F NA YN +G V + LL+K
Sbjct: 1385 IQNKCSCGNYRSVQEFLTDMKQVFANAELYNCRGSHVLSCMEKTEQCLLALLQKHLPGHP 1444
Query: 245 LYRPIQEKFDEKSFDDELQASS 266
R + KF ++ DDE + S
Sbjct: 1445 YVRRKRRKFPDRLADDEGDSDS 1466
>TF1A_HUMAN (O15164) Transcription intermediary factor 1-alpha
(TIF1-alpha) (Tripartite motif-containing protein 24)
Length = 1050
Score = 68.2 bits (165), Expect = 6e-11
Identities = 38/114 (33%), Positives = 66/114 (57%), Gaps = 10/114 (8%)
Query: 173 DPVALNLHDYFDIIKHPMDLGTVKSKLAK--NAYSTPAEFADDVKLTFKNALTYNPKGHD 230
DPV L + DY+ IIK+PMDL T+K +L + + YS P +F D +L F+N +N +
Sbjct: 926 DPVPLTVPDYYKIIKNPMDLSTIKKRLQEDYSMYSKPEDFVADFRLIFQNCAEFNEPDSE 985
Query: 231 VNTAAMQLLEKFEELYRPI--QEKFDEKSFDDELQASSW------NHVEPERER 276
V A ++L FEEL + + +++F + F +E + + + + V+P ++R
Sbjct: 986 VANAGIKLENYFEELLKNLYPEKRFPKPEFRNESEDNKFSDDSDDDFVQPRKKR 1039
>CBP1_CAEEL (P34545) Protein cbp-1
Length = 2056
Score = 65.9 bits (159), Expect = 3e-10
Identities = 37/97 (38%), Positives = 49/97 (50%)
Query: 155 ILQKLMKTKIGWIFSSPVDPVALNLHDYFDIIKHPMDLGTVKSKLAKNAYSTPAEFADDV 214
+ +KL K++ F PVD LN+ DY +IIK PMDL TV KL Y +F DD+
Sbjct: 876 VWEKLDKSEDAAPFRVPVDAKLLNIPDYHEIIKRPMDLETVHKKLYAGQYQNAGQFCDDI 935
Query: 215 KLTFKNALTYNPKGHDVNTAAMQLLEKFEELYRPIQE 251
L NA YN K V ++L E F P+ +
Sbjct: 936 WLMLDNAWLYNRKNSKVYKYGLKLSEMFVSEMDPVMK 972
>TF1A_MOUSE (Q64127) Transcription intermediary factor 1-alpha
(TIF1-alpha) (Tripartite motif-containing protein 24)
Length = 1051
Score = 65.5 bits (158), Expect = 4e-10
Identities = 38/114 (33%), Positives = 64/114 (55%), Gaps = 10/114 (8%)
Query: 173 DPVALNLHDYFDIIKHPMDLGTVKSKLAKN--AYSTPAEFADDVKLTFKNALTYNPKGHD 230
DPV L + DY+ IIK+PMDL T+K +L ++ Y+ P +F D +L F+N +N +
Sbjct: 927 DPVPLTVPDYYKIIKNPMDLSTIKKRLQEDYCMYTKPEDFVADFRLIFQNCAEFNEPDSE 986
Query: 231 VNTAAMQLLEKFEELYRPI--QEKFDEKSFDDELQ------ASSWNHVEPERER 276
V A ++L FEEL + + +++F + F E + S + V+P ++R
Sbjct: 987 VANAGIKLESYFEELLKNLYPEKRFPKVEFRHEAEDCKFSDDSDDDFVQPRKKR 1040
>BA2B_CHICK (Q9DE13) Bromodomain adjacent to zinc finger domain 2B
(Extracellular matrix protein F22)
Length = 2130
Score = 58.5 bits (140), Expect = 4e-08
Identities = 38/123 (30%), Positives = 57/123 (45%), Gaps = 5/123 (4%)
Query: 127 GNKRPFPAEKELKRSKSEVGSAMKACGQILQKLMKTKIGWIFSSPVDPVALNLHDYFDII 186
G + F A K+ KR S+ + C IL +L + W F PV+ + Y +I
Sbjct: 2009 GKQENFTAIKKPKRDDSK---DLAICSMILSELETHEDAWPFLLPVNLKLVP--GYKKVI 2063
Query: 187 KHPMDLGTVKSKLAKNAYSTPAEFADDVKLTFKNALTYNPKGHDVNTAAMQLLEKFEELY 246
K PMD T++ KL Y F+ DV+L F N T+N D+ A + + FE+ +
Sbjct: 2064 KKPMDFSTIRDKLTSGQYPNVEAFSLDVRLVFDNCETFNEDDSDIGRAGHNMRKYFEKKW 2123
Query: 247 RPI 249
I
Sbjct: 2124 TEI 2126
>BA1A_HUMAN (Q9NRL2) Bromodomain adjacent to zinc finger domain
protein 1A (ATP-utilizing chromatin assembly and
remodeling factor 1) (hACF1) (ATP-dependent chromatin
remodelling protein) (Williams syndrome transcription
factor-related chromatin remodelin
Length = 1556
Score = 57.8 bits (138), Expect = 7e-08
Identities = 39/138 (28%), Positives = 64/138 (46%), Gaps = 7/138 (5%)
Query: 106 KSRSSHNGGGSAKKSANKKFSGNKRPFPAEKEL---KRSKSEVGSA--MKACGQILQKLM 160
+SRS + + + + K KR P + +RS G + A Q++ +L+
Sbjct: 1387 QSRSVNIASKLSLQESESKRRCKKRQSPEPSPVTLGRRSSGRQGGVHELSAFEQLVVELV 1446
Query: 161 KTKIGWIFSSPVDPVALNLHDYFDIIKHPMDLGTVKSKLAKNAYSTPAEFADDVKLTFKN 220
+ W F V + + DY+DIIK P+ L ++ K+ K Y +EF DD++L F N
Sbjct: 1447 RHDDSWPFLKLVSKI--QVPDYYDIIKKPIALNIIREKVNKCEYKLASEFIDDIELMFSN 1504
Query: 221 ALTYNPKGHDVNTAAMQL 238
YNP+ A +L
Sbjct: 1505 CFEYNPRNTSEAKAGTRL 1522
Database: sprot
Posted date: Nov 25, 2004 10:54 AM
Number of letters in database: 59,974,054
Number of sequences in database: 164,201
Lambda K H
0.310 0.129 0.365
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 70,611,080
Number of Sequences: 164201
Number of extensions: 3391561
Number of successful extensions: 23354
Number of sequences better than 10.0: 564
Number of HSP's better than 10.0 without gapping: 155
Number of HSP's successfully gapped in prelim test: 425
Number of HSP's that attempted gapping in prelim test: 19196
Number of HSP's gapped (non-prelim): 2791
length of query: 559
length of database: 59,974,054
effective HSP length: 115
effective length of query: 444
effective length of database: 41,090,939
effective search space: 18244376916
effective search space used: 18244376916
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 68 (30.8 bits)
Medicago: description of AC144564.17