BLAST2 result
BLASTP 2.2.2 [Dec-14-2001]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= AC144513.1 + phase: 0
(428 letters)
Database: sprot
164,201 sequences; 59,974,054 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
P2C1_ARATH (P49597) Protein phosphatase 2C ABI1 (EC 3.1.3.16) (P... 105 2e-22
P2C2_ARATH (O04719) Protein phosphatase 2C ABI2 (EC 3.1.3.16) (P... 100 7e-21
FEM2_HUMAN (P49593) Ca(2+)/calmodulin-dependent protein kinase p... 84 7e-16
FEM2_RAT (Q9WVR7) Ca(2+)/calmodulin-dependent protein kinase pho... 79 2e-14
P2C2_CAEEL (P49596) Probable protein phosphatase 2C T23F11.1 (EC... 78 5e-14
P2C2_SCHPO (Q09172) Protein phosphatase 2C homolog 2 (EC 3.1.3.1... 75 2e-13
P2C1_YEAST (P35182) Protein phosphatase 2C homolog 1 (EC 3.1.3.1... 74 5e-13
P2C4_ARATH (P49598) Protein phosphatase 2C (EC 3.1.3.16) (PP2C) 74 9e-13
P2CG_HUMAN (O15355) Protein phosphatase 2C gamma isoform (EC 3.1... 72 2e-12
P2CB_RAT (P35815) Protein phosphatase 2C beta isoform (EC 3.1.3.... 72 2e-12
P2CB_MOUSE (P36993) Protein phosphatase 2C beta isoform (EC 3.1.... 72 2e-12
P2CB_HUMAN (O75688) Protein phosphatase 2C beta isoform (EC 3.1.... 72 2e-12
P2CB_BOVIN (O62830) Protein phosphatase 2C beta isoform (EC 3.1.... 72 2e-12
P2C1_CAEEL (P49595) Probable protein phosphatase 2C F42G9.1 (EC ... 72 2e-12
P2CA_HUMAN (P35813) Protein phosphatase 2C alpha isoform (EC 3.1... 71 6e-12
P2CA_RAT (P20650) Protein phosphatase 2C alpha isoform (EC 3.1.3... 70 8e-12
P2CA_RABIT (P35814) Protein phosphatase 2C alpha isoform (EC 3.1... 70 8e-12
P2CA_MOUSE (P49443) Protein phosphatase 2C alpha isoform (EC 3.1... 70 1e-11
P2CA_BOVIN (O62829) Protein phosphatase 2C alpha isoform (EC 3.1... 70 1e-11
P2C3_SCHPO (Q09173) Protein phosphatase 2C homolog 3 (EC 3.1.3.1... 70 1e-11
>P2C1_ARATH (P49597) Protein phosphatase 2C ABI1 (EC 3.1.3.16)
(PP2C) (Abscisic acid-insensitive 1)
Length = 434
Score = 105 bits (262), Expect = 2e-22
Identities = 82/271 (30%), Positives = 125/271 (45%), Gaps = 43/271 (15%)
Query: 61 DPSTAFSVFAIFDGHNGISAAIYTKEN----LLNNVLSAIPQDISRDAWLQALPRALVVG 116
DP +A F ++DGH G A Y +E L + P D WL+ +AL
Sbjct: 165 DPQSAAHFFGVYDGHGGSQVANYCRERMHLALAEEIAKEKPMLCDGDTWLEKWKKALFNS 224
Query: 117 FVKTDTEFQKKG-ETSGTTATFVIVDGWTVTVASVGDSRCILDTQGGVVSLLTVDHRLEE 175
F++ D+E + ET G+T+ +V + VA+ GDSR +L +G L+VDH+ +
Sbjct: 225 FLRVDSEIESVAPETVGSTSVVAVVFPSHIFVANCGDSRAVL-CRGKTALPLSVDHKPDR 283
Query: 176 NVEERERVTASGGEVGRLNIFGGNEVGPLRCWPGGLCLSRSIGDTDVGEYIVPIPHVKQV 235
+E R+ A+GG+V + N G V G L +SRSIGD + I+P P V V
Sbjct: 284 E-DEAARIEAAGGKVIQWN---GARVF------GVLAMSRSIGDRYLKPSIIPDPEVTAV 333
Query: 236 KLSSAGGRLIIASDGIWDTLSNDIAAMSCRGL---------------------------P 268
K LI+ASDG+WD ++++ A R P
Sbjct: 334 KRVKEDDCLILASDGVWDVMTDEEACEMARKRILLWHKKNAVAGDASLLADERRKEGKDP 393
Query: 269 AELAAKLVVKEALRSRGLKDDTTCLVVDIIP 299
A ++A + + RG KD+ + +VVD+ P
Sbjct: 394 AAMSAAEYLSKLAIQRGSKDNISVVVVDLKP 424
>P2C2_ARATH (O04719) Protein phosphatase 2C ABI2 (EC 3.1.3.16)
(PP2C) (Abscisic acid-insensitive 2)
Length = 423
Score = 100 bits (249), Expect = 7e-21
Identities = 80/270 (29%), Positives = 129/270 (47%), Gaps = 44/270 (16%)
Query: 61 DPSTAFSVFAIFDGHNGISAAIYTKEN----LLNNVLSAIPQDISRDAWLQALPRALVVG 116
+P + F ++DGH G A Y +E L ++ P+ D W + +AL
Sbjct: 153 NPHLSAHFFGVYDGHGGSQVANYCRERMHLALTEEIVKEKPEFCDGDTWQEKWKKALFNS 212
Query: 117 FVKTDTEFQKKG---ETSGTTATFVIVDGWTVTVASVGDSRCILDTQGGVVSLLTVDHRL 173
F++ D+E + ET G+T+ +V + VA+ GDSR +L +G L+VDH+
Sbjct: 213 FMRVDSEIETVAHAPETVGSTSVVAVVFPTHIFVANCGDSRAVL-CRGKTPLALSVDHKP 271
Query: 174 EENVEERERVTASGGEVGRLNIFGGNEVGPLRCWPGGLCLSRSIGDTDVGEYIVPIPHVK 233
+ + +E R+ A+GG+V R N G V G L +SRSIGD + ++P P V
Sbjct: 272 DRD-DEAARIEAAGGKVIRWN---GARVF------GVLAMSRSIGDRYLKPSVIPDPEVT 321
Query: 234 QVKLSSAGGRLIIASDGIWDTLSN----DIA-----------AMSCRGL----------- 267
V+ LI+ASDG+WD ++N D+A AM+ L
Sbjct: 322 SVRRVKEDDCLILASDGLWDVMTNEEVCDLARKRILLWHKKNAMAGEALLPAEKRGEGKD 381
Query: 268 PAELAAKLVVKEALRSRGLKDDTTCLVVDI 297
PA ++A + + +G KD+ + +VVD+
Sbjct: 382 PAAMSAAEYLSKMALQKGSKDNISVVVVDL 411
>FEM2_HUMAN (P49593) Ca(2+)/calmodulin-dependent protein kinase
phosphatase (EC 3.1.3.16) (CaM-kinase phosphatase)
(CaMKPase) (Partner of PIX 2) (hFEM-2) (Protein
phosphatase 1F)
Length = 454
Score = 84.0 bits (206), Expect = 7e-16
Identities = 76/239 (31%), Positives = 112/239 (46%), Gaps = 33/239 (13%)
Query: 69 FAIFDGHNGISAAIYTKENLLNNVLSAIPQDISRDAWLQALPR-ALVVGFVKTDTEFQKK 127
FA+FDGH G+ AA Y ++ N +R L P AL F +TD F +K
Sbjct: 194 FAVFDGHGGVDAARYAAVHVHTNA--------ARQPELPTDPEGALREAFRRTDQMFLRK 245
Query: 128 GET----SGTTATFVIVDGWTVTVASVGDSRCILDTQGGVVSLLTVDHRLEENVEERERV 183
+ SGTT ++ G T+ VA +GDS+ IL QG VV L+ HR E +E+ R+
Sbjct: 246 AKRERLQSGTTGVCALIAGATLHVAWLGDSQVILVQQGQVVKLME-PHR-PERQDEKARI 303
Query: 184 TASGGEVGRLNIFGGNEVGPLRCW--PGGLCLSRSIGDTDVGEYIVPIPHVKQVKLSSAG 241
A GG V ++ CW G L +SR+IGD Y+ L+ +
Sbjct: 304 EALGGFVSHMD-----------CWRVNGTLAVSRAIGDVFQKPYVSGEADAASRALTGSE 352
Query: 242 GRLIIASDGIWDTLSN-DIAAMSCRGLPAELAAKLVVKE----ALRSRGLKDDTTCLVV 295
L++A DG +D + + ++ + L + + L V E A R RG D+ T +VV
Sbjct: 353 DYLLLACDGFFDVVPHQEVVGLVQSHLTRQQGSGLRVAEELVAAARERGSHDNITVMVV 411
>FEM2_RAT (Q9WVR7) Ca(2+)/calmodulin-dependent protein kinase
phosphatase (EC 3.1.3.16) (CaM-kinase phosphatase)
(CaMKPase) (Partner of PIX 2) (Protein phosphatase 1F)
Length = 450
Score = 79.0 bits (193), Expect = 2e-14
Identities = 73/238 (30%), Positives = 111/238 (45%), Gaps = 31/238 (13%)
Query: 69 FAIFDGHNGISAAIYTKENLLNNVLSAIPQDISRDAWLQALPRALVVGFVKTDTEFQKKG 128
FA+FDGH G+ AA Y ++ N S P+ ++ A AL F TD F +K
Sbjct: 190 FAVFDGHGGVDAARYASVHVHTNA-SHQPELLTDPA------AALKEAFRHTDQMFLQKA 242
Query: 129 ET----SGTTATFVIVDGWTVTVASVGDSRCILDTQGGVVSLLTVDHRLEENVEERERVT 184
+ SGTT ++ G + VA +GDS+ IL QG VV L+ + E +E+ R+
Sbjct: 243 KRERLQSGTTGVCALITGAALHVAWLGDSQVILVQQGQVVKLM--EPHKPERQDEKSRIE 300
Query: 185 ASGGEVGRLNIFGGNEVGPLRCW--PGGLCLSRSIGDTDVGEYIVPIPHVKQVKLSSAGG 242
A GG V ++ CW G L +SR+IGD Y+ +L+
Sbjct: 301 ALGGFVSLMD-----------CWRVNGTLAVSRAIGDVFQKPYVSGEADAASRELTGLED 349
Query: 243 RLIIASDGIWDTL-SNDIAAMSCRGLPAELAAKLVVKEAL----RSRGLKDDTTCLVV 295
L++A DG +D + ++I + L + + + V E L R RG D+ T +VV
Sbjct: 350 YLLLACDGFFDVVPHHEIPGLVHGHLLRQKGSGMHVAEELVAVARDRGSHDNITVMVV 407
>P2C2_CAEEL (P49596) Probable protein phosphatase 2C T23F11.1 (EC
3.1.3.16) (PP2C)
Length = 356
Score = 77.8 bits (190), Expect = 5e-14
Identities = 73/247 (29%), Positives = 110/247 (43%), Gaps = 39/247 (15%)
Query: 58 VPGDPSTAFSVFAIFDGHNGISAAIYTKENLLNNVLSAIPQDISRDAWLQALPRALVVGF 117
+P DP AF FA++DGH G + Y+ NL V++ ++ S +A+ + GF
Sbjct: 46 LPDDPKCAF--FAVYDGHGGSKVSQYSGINLHKKVVAQ--KEFSEGNMKEAIEK----GF 97
Query: 118 VKTDTEF----QKKGETSGTTATFVIVDGWTVTVASVGDSRCILDTQGGVVSLLTVDHRL 173
++ D + + K + SGTTA V++ V + GDSR + G L + DH+
Sbjct: 98 LELDQQMRVDEETKDDVSGTTAVVVLIKEGDVYCGNAGDSRAVSSVVGEARPL-SFDHKP 156
Query: 174 EENVEERERVTASGG--EVGRLNIFGGNEVGPLRCWPGGLCLSRSIGD-------TDVGE 224
E R R+ A+GG E R+N G L LSR++GD T E
Sbjct: 157 SHETEAR-RIIAAGGWVEFNRVN--------------GNLALSRALGDFAFKNCDTKPAE 201
Query: 225 --YIVPIPHVKQVKLSSAGGRLIIASDGIWDTLSNDIAAMSCRGLPAELAAKLVVKEALR 282
+ P V KL+ +++A DGIWD ++N R AE + E L
Sbjct: 202 EQIVTAFPDVITDKLTPDHEFIVLACDGIWDVMTNQEVVDFVREKLAEKRDPQSICEELL 261
Query: 283 SRGLKDD 289
+R L D
Sbjct: 262 TRCLAPD 268
>P2C2_SCHPO (Q09172) Protein phosphatase 2C homolog 2 (EC 3.1.3.16)
(PP2C-2)
Length = 370
Score = 75.5 bits (184), Expect = 2e-13
Identities = 69/238 (28%), Positives = 109/238 (44%), Gaps = 41/238 (17%)
Query: 61 DPSTAFSVFAIFDGHNGISAAIYTKENLLNNVLSAIPQDISRDAWLQALPRALVVGFVKT 120
+P T+F F +FDGH G A Y +++L + + S W AL GF+
Sbjct: 53 NPPTSF--FGVFDGHGGDRVAKYCRQHLPDIIKS------QPSFWKGNYDEALKSGFLAA 104
Query: 121 DTEFQK----KGETSGTTA-TFVIVDGWTVTVASVGDSRCILDTQGGVVSLLTVDHRLEE 175
D + + + SG TA T +IVD + A+ GDSR +L + G L+ DH+
Sbjct: 105 DNALMQDRDMQEDPSGCTATTALIVDHQVIYCANAGDSRTVLGRK-GTAEPLSFDHKPNN 163
Query: 176 NVEERERVTASGG--EVGRLNIFGGNEVGPLRCWPGGLCLSRSIGDTDV---------GE 224
+V E+ R+TA+GG + GR+N G L LSR+IGD + +
Sbjct: 164 DV-EKARITAAGGFIDFGRVN--------------GSLALSRAIGDFEYKKDSSLPPEKQ 208
Query: 225 YIVPIPHVKQVKLSSAGGRLIIASDGIWDTLSN-DIAAMSCRGLPAELAAKLVVKEAL 281
+ P V + LI+A DGIWD S+ + RG+ A + +++ + +
Sbjct: 209 IVTAFPDVVIHNIDPDDEFLILACDGIWDCKSSQQVVEFVRRGIVARQSLEVICENLM 266
>P2C1_YEAST (P35182) Protein phosphatase 2C homolog 1 (EC 3.1.3.16)
(PP2C-1)
Length = 281
Score = 74.3 bits (181), Expect = 5e-13
Identities = 74/248 (29%), Positives = 114/248 (45%), Gaps = 43/248 (17%)
Query: 69 FAIFDGHNGISAAIYTKENLLNNVLSAIPQDISRDAWLQALPRALVVGFVKTDTEFQKK- 127
FA+FDGH GI A+ + ++L + I D +RD + L F+ D E K
Sbjct: 54 FAVFDGHAGIQASKWCGKHLHTIIEQNILADETRD-----VRDVLNDSFLAIDEEINTKL 108
Query: 128 GETSGTTATFVIVDGWTVT------------------VASVGDSRCILDTQGGVVSLLTV 169
SG TA V V W + A+VGDSR +L G + L T
Sbjct: 109 VGNSGCTAA-VCVLRWELPDSVSDDSMDLAQHQRKLYTANVGDSRIVLFRNGNSIRL-TY 166
Query: 170 DHRLEENVEERERVTASGGEVGRLNIFGGNEVGPLRCWPGGLCLSRSIGDTDVGEYIVPI 229
DH+ + +E +RV +GG + + + G L ++RS+GD +V
Sbjct: 167 DHKASDTLE-MQRVEQAGGLIMKSRV------------NGMLAVTRSLGDKFFDSLVVGS 213
Query: 230 PHVKQVKLSSAGGRLIIASDGIWDTLSNDIAAMSCRGL--PAELAAKLVVKEALRSRGLK 287
P V+++S LI+A DG+WD + + A + + P E AAK++V+ AL + G
Sbjct: 214 PFTTSVEITSEDKFLILACDGLWDVIDDQDACELIKDITEPNE-AAKVLVRYALEN-GTT 271
Query: 288 DDTTCLVV 295
D+ T +VV
Sbjct: 272 DNVTVMVV 279
>P2C4_ARATH (P49598) Protein phosphatase 2C (EC 3.1.3.16) (PP2C)
Length = 399
Score = 73.6 bits (179), Expect = 9e-13
Identities = 73/269 (27%), Positives = 120/269 (44%), Gaps = 57/269 (21%)
Query: 69 FAIFDGHNGISAAIYTKENLLNNVLSAIPQDISRDAWLQALPRALVVGFVKTDTEFQKKG 128
+ +FDGH A +E L ++++ + ++ D W + + V F K D E ++
Sbjct: 138 YGVFDGHGCSHVAEKCRERL-HDIVKKEVEVMASDEWTETM----VKSFQKMDKEVSQRE 192
Query: 129 -------------------------ETSGTTATFVIVDGWTVTVASVGDSRCILDTQGGV 163
+ G+TA +V + V++ GDSR +L + GV
Sbjct: 193 CNLVVNGATRSMKNSCRCELQSPQCDAVGSTAVVSVVTPEKIIVSNCGDSRAVL-CRNGV 251
Query: 164 VSLLTVDHRLEENVEERERVTASGGEVGRLNIFGGNEVGPLRCWPGGLCLSRSIGDTDVG 223
L+VDH+ + +E R+ +GG R+ + G V G L +SR+IGD +
Sbjct: 252 AIPLSVDHK-PDRPDELIRIQQAGG---RVIYWDGARV------LGVLAMSRAIGDNYLK 301
Query: 224 EYIVPIPHVKQVKLSSAGGRLIIASDGIWDTLSND----IAAMSCRGLPA---------- 269
Y++P P V + LI+ASDG+WD + N+ +A M RG A
Sbjct: 302 PYVIPDPEVTVTDRTDEDECLILASDGLWDVVPNETACGVARMCLRGAGAGDDSDAAHNA 361
Query: 270 -ELAAKLVVKEALRSRGLKDDTTCLVVDI 297
AA L+ K AL +R D+ + +VVD+
Sbjct: 362 CSDAALLLTKLAL-ARQSSDNVSVVVVDL 389
>P2CG_HUMAN (O15355) Protein phosphatase 2C gamma isoform (EC
3.1.3.16) (PP2C-gamma) (Protein phosphatase
magnesium-dependent 1 gamma) (Protein phosphatase 1C)
Length = 546
Score = 72.4 bits (176), Expect = 2e-12
Identities = 67/240 (27%), Positives = 111/240 (45%), Gaps = 45/240 (18%)
Query: 125 QKKGETSGTTATFVIVDGWTVTVASVGDSRCILDTQGGVVSLLTVDHRLEENVEERERVT 184
++ G SGTTA ++ G + VA+ GDSRC++ G + ++ DH+ E+ V E R+
Sbjct: 321 EEPGSDSGTTAVVALIRGKQLIVANAGDSRCVVSEAGKALD-MSYDHKPEDEV-ELARIK 378
Query: 185 ASGGEV---GRLNIFGGNEVGPLRCWPGGLCLSRSIGD---------TDVGEYIVPIPHV 232
+GG+V GR+N GGL LSR+IGD + I +P +
Sbjct: 379 NAGGKVTMDGRVN--------------GGLNLSRAIGDHFYKRNKNLPPEEQMISALPDI 424
Query: 233 KQVKLSSAGGRLIIASDGIWDTLSND------IAAMSCRGLPAELAAKLVVKEALRSRGL 286
K + L+ ++IA DGIW+ +S+ + +S R EL + E L + L
Sbjct: 425 KVLTLTDDHEFMVIACDGIWNVMSSQEVVDFIQSKISQRDENGELRLLSSIVEELLDQCL 484
Query: 287 KDDT----------TCLVVDIIPSDHPVLLP-TPKKKHNMLTTLFFGKKSENSTNKATSK 335
DT TC+++ P + L P + K+K + + +++ NS K +K
Sbjct: 485 APDTSGDGTGCDNMTCIIICFKPRNTAELQPESGKRKLEEVLSTEGAEENGNSDKKKKAK 544
>P2CB_RAT (P35815) Protein phosphatase 2C beta isoform (EC 3.1.3.16)
(PP2C-beta) (IA) (Protein phosphatase 1B)
Length = 390
Score = 72.4 bits (176), Expect = 2e-12
Identities = 58/216 (26%), Positives = 101/216 (45%), Gaps = 39/216 (18%)
Query: 66 FSVFAIFDGHNGISAAIYTKENLLNNVLS------AIPQDISRDAWLQALPRALVVGFVK 119
+S FA++DGH G A Y +LL ++ + A + + ++ + + GF+K
Sbjct: 53 WSFFAVYDGHAGSRVANYCSTHLLEHITTNEDFRAADKSGFALEPSVENVKTGIRTGFLK 112
Query: 120 TD------TEFQKKGETSGTTATFVIVDGWTVTVASVGDSRCILDTQGGVVSLLTVDHRL 173
D ++ + + SG+TA V++ + + GDSR +L + G V T DH+
Sbjct: 113 IDEYMRNFSDLRNGMDRSGSTAVGVMISPTHIYFINCGDSRAVL-CRNGQVCFSTQDHK- 170
Query: 174 EENVEERERVTASGGEV--GRLNIFGGNEVGPLRCWPGGLCLSRSIGDTD---------V 222
N E+ER+ +GG V R+N G L +SR++GD D
Sbjct: 171 PCNPMEKERIQNAGGSVMIQRVN--------------GSLAVSRALGDYDYKCVDGKGPT 216
Query: 223 GEYIVPIPHVKQVKLSSAGGRLIIASDGIWDTLSND 258
+ + P P V ++ + +++A DGIWD +SN+
Sbjct: 217 EQLVSPEPEVYEILRAEEDEFVVLACDGIWDVMSNE 252
>P2CB_MOUSE (P36993) Protein phosphatase 2C beta isoform (EC
3.1.3.16) (PP2C-beta) (IA) (Protein phosphatase 1B)
Length = 390
Score = 72.4 bits (176), Expect = 2e-12
Identities = 59/216 (27%), Positives = 102/216 (46%), Gaps = 39/216 (18%)
Query: 66 FSVFAIFDGHNGISAAIYTKENLLNNVLS------AIPQDISRDAWLQALPRALVVGFVK 119
+S FA++DGH G A Y +LL ++ + A + + ++++ + GF+K
Sbjct: 53 WSFFAVYDGHAGSRVANYCSTHLLEHITTNEDFRAADKSGSALEPSVESVKTGIRTGFLK 112
Query: 120 TD------TEFQKKGETSGTTATFVIVDGWTVTVASVGDSRCILDTQGGVVSLLTVDHRL 173
D ++ + + SG+TA V+V + + GDSR +L + G V T DH+
Sbjct: 113 IDEYMRNFSDLRNGMDRSGSTAVGVMVSPTHMYFINCGDSRAVL-CRNGQVCFSTQDHK- 170
Query: 174 EENVEERERVTASGGEV--GRLNIFGGNEVGPLRCWPGGLCLSRSIGDTD---------V 222
N E+ER+ +GG V R+N G L +SR++GD D
Sbjct: 171 PCNPVEKERIQNAGGSVMIQRVN--------------GSLAVSRALGDYDYKCVDGKGPT 216
Query: 223 GEYIVPIPHVKQVKLSSAGGRLIIASDGIWDTLSND 258
+ + P P V ++ + +++A DGIWD +SN+
Sbjct: 217 EQLVSPEPEVYEIVRAEEDEFVVLACDGIWDVMSNE 252
>P2CB_HUMAN (O75688) Protein phosphatase 2C beta isoform (EC
3.1.3.16) (PP2C-beta)
Length = 479
Score = 72.4 bits (176), Expect = 2e-12
Identities = 59/216 (27%), Positives = 101/216 (46%), Gaps = 39/216 (18%)
Query: 66 FSVFAIFDGHNGISAAIYTKENLLNNVLS------AIPQDISRDAWLQALPRALVVGFVK 119
+S FA++DGH G A Y +LL ++ + A + + ++ + + GF+K
Sbjct: 53 WSFFAVYDGHAGSRVANYCSTHLLEHITTNEDFRAAGKSGSALELSVENVKNGIRTGFLK 112
Query: 120 TD------TEFQKKGETSGTTATFVIVDGWTVTVASVGDSRCILDTQGGVVSLLTVDHRL 173
D ++ + + SG+TA V++ + + GDSR +L + G V T DH+
Sbjct: 113 IDEYMRNFSDLRNGMDRSGSTAVGVMISPKHIYFINCGDSRAVL-YRNGQVCFSTQDHK- 170
Query: 174 EENVEERERVTASGGEV--GRLNIFGGNEVGPLRCWPGGLCLSRSIGDTD---------V 222
N E+ER+ +GG V R+N G L +SR++GD D
Sbjct: 171 PCNPREKERIQNAGGSVMIQRVN--------------GSLAVSRALGDYDYKCVDGKGPT 216
Query: 223 GEYIVPIPHVKQVKLSSAGGRLIIASDGIWDTLSND 258
+ + P P V ++ + +I+A DGIWD +SN+
Sbjct: 217 EQLVSPEPEVYEILRAEEDEFIILACDGIWDVMSNE 252
>P2CB_BOVIN (O62830) Protein phosphatase 2C beta isoform (EC
3.1.3.16) (PP2C-beta)
Length = 387
Score = 72.4 bits (176), Expect = 2e-12
Identities = 59/216 (27%), Positives = 101/216 (46%), Gaps = 39/216 (18%)
Query: 66 FSVFAIFDGHNGISAAIYTKENLLNNVLS------AIPQDISRDAWLQALPRALVVGFVK 119
+S FA++DGH G A Y +LL ++ + A + + ++ + + GF+K
Sbjct: 53 WSFFAVYDGHAGSRVANYCSTHLLEHITNNEDFRAAGKSGSALEPSVENVKNGIRTGFLK 112
Query: 120 TD------TEFQKKGETSGTTATFVIVDGWTVTVASVGDSRCILDTQGGVVSLLTVDHRL 173
D ++ + + SG+TA V++ + + GDSR +L + G V T DH+
Sbjct: 113 IDEYMRNFSDLRNGMDRSGSTAVGVMISPKHIYFINCGDSRAVL-YRSGQVCFSTQDHK- 170
Query: 174 EENVEERERVTASGGEV--GRLNIFGGNEVGPLRCWPGGLCLSRSIGDTD---------V 222
N E+ER+ +GG V R+N G L +SR++GD D
Sbjct: 171 PCNPREKERIQNAGGSVMIQRVN--------------GSLAVSRALGDYDYKCVDGKGPT 216
Query: 223 GEYIVPIPHVKQVKLSSAGGRLIIASDGIWDTLSND 258
+ + P P V ++ + +I+A DGIWD +SN+
Sbjct: 217 EQLVSPEPEVYEILRAEEDEFIILACDGIWDVMSNE 252
>P2C1_CAEEL (P49595) Probable protein phosphatase 2C F42G9.1 (EC
3.1.3.16) (PP2C)
Length = 491
Score = 72.4 bits (176), Expect = 2e-12
Identities = 60/174 (34%), Positives = 88/174 (50%), Gaps = 27/174 (15%)
Query: 128 GETSGTTATFVIVDGWTVTVASVGDSRCILDTQGGVVSLLTVDHRLEENVEERERVTASG 187
GE SGTTA +V V VA+ GDSR +L G V L+VDH+ E+ V E R+ A+G
Sbjct: 312 GEDSGTTACVCLVGKDKVIVANAGDSRAVLCRNGKAVD-LSVDHKPEDEV-ETNRIHAAG 369
Query: 188 GEV--GRLNIFGGNEVGPLRCWPGGLCLSRSIGD------TDVG---EYIVPIPHVKQVK 236
G++ GR+N GGL LSR+ GD ++G + I +P VK
Sbjct: 370 GQIEDGRVN--------------GGLNLSRAFGDHAYKKNQELGLKEQMITALPDVKIEA 415
Query: 237 LSSAGGRLIIASDGIWDTLSNDIAAMSCRGLPAELAAKLVVKEALRSRGLKDDT 290
L+ +++A DGIW+++ + R L A+ ++ V +AL L D T
Sbjct: 416 LTPEDEFIVVACDGIWNSMESQQVVDFVRDLLAKGSSCAEVCDALCDACLADST 469
>P2CA_HUMAN (P35813) Protein phosphatase 2C alpha isoform (EC
3.1.3.16) (PP2C-alpha) (IA) (Protein phosphatase 1A)
Length = 382
Score = 70.9 bits (172), Expect = 6e-12
Identities = 67/229 (29%), Positives = 108/229 (46%), Gaps = 42/229 (18%)
Query: 54 DCHR-VPGDPS--TAFSVFAIFDGHNGISAAIYTKENLLNNVLSAIPQDISRDAW---LQ 107
D H V G PS ++S FA++DGH G A Y E+LL+++ + QD A ++
Sbjct: 38 DAHTAVIGLPSGLESWSFFAVYDGHAGSQVAKYCCEHLLDHITN--NQDFKGSAGAPSVE 95
Query: 108 ALPRALVVGFVKTD------TEFQKKGETSGTTATFVIVDGWTVTVASVGDSRCILDTQG 161
+ + GF++ D +E + + SG+TA V++ + GDSR +L +
Sbjct: 96 NVKNGIRTGFLEIDEHMRVMSEKKHGADRSGSTAVGVLISPQHTYFINCGDSRGLL-CRN 154
Query: 162 GVVSLLTVDHRLEENVEERERVTASGGEV--GRLNIFGGNEVGPLRCWPGGLCLSRSIGD 219
V T DH+ N E+ER+ +GG V R+N G L +SR++GD
Sbjct: 155 RKVHFFTQDHK-PSNPLEKERIQNAGGSVMIQRVN--------------GSLAVSRALGD 199
Query: 220 TD---------VGEYIVPIPHVKQVKLSSAGGR-LIIASDGIWDTLSND 258
D + + P P V ++ S + +I+A DGIWD + N+
Sbjct: 200 FDYKCVHGKGPTEQLVSPEPEVHDIERSEEDDQFIILACDGIWDVMGNE 248
>P2CA_RAT (P20650) Protein phosphatase 2C alpha isoform (EC
3.1.3.16) (PP2C-alpha) (IA) (Protein phosphatase 1A)
Length = 382
Score = 70.5 bits (171), Expect = 8e-12
Identities = 67/229 (29%), Positives = 107/229 (46%), Gaps = 42/229 (18%)
Query: 54 DCHR-VPGDPS--TAFSVFAIFDGHNGISAAIYTKENLLNNVLSAIPQDISRDAW---LQ 107
D H V G PS +S FA++DGH G A Y E+LL+++ + QD A ++
Sbjct: 38 DAHTAVIGLPSGLETWSFFAVYDGHAGSQVAKYCCEHLLDHITN--NQDFKGSAGAPSVE 95
Query: 108 ALPRALVVGFVKTD------TEFQKKGETSGTTATFVIVDGWTVTVASVGDSRCILDTQG 161
+ + GF++ D +E + + SG+TA V++ + GDSR +L +
Sbjct: 96 NVKNGIRTGFLEIDEHMRVMSEKKHGADRSGSTAVGVLISPQHTYFINCGDSRGLL-CRN 154
Query: 162 GVVSLLTVDHRLEENVEERERVTASGGEV--GRLNIFGGNEVGPLRCWPGGLCLSRSIGD 219
V T DH+ N E+ER+ +GG V R+N G L +SR++GD
Sbjct: 155 RKVHFFTQDHK-PSNPLEKERIQNAGGSVMIQRVN--------------GSLAVSRALGD 199
Query: 220 TD---------VGEYIVPIPHVKQVKLSSAGGR-LIIASDGIWDTLSND 258
D + + P P V ++ S + +I+A DGIWD + N+
Sbjct: 200 FDYKCVHGKGPTEQLVSPEPEVHDIERSEEDDQFIILACDGIWDVMGNE 248
>P2CA_RABIT (P35814) Protein phosphatase 2C alpha isoform (EC
3.1.3.16) (PP2C-alpha) (IA) (Protein phosphatase 1A)
Length = 382
Score = 70.5 bits (171), Expect = 8e-12
Identities = 67/229 (29%), Positives = 107/229 (46%), Gaps = 42/229 (18%)
Query: 54 DCHR-VPGDPS--TAFSVFAIFDGHNGISAAIYTKENLLNNVLSAIPQDISRDAW---LQ 107
D H V G PS +S FA++DGH G A Y E+LL+++ + QD A ++
Sbjct: 38 DAHTAVIGLPSGLETWSFFAVYDGHAGSQVAKYCCEHLLDHITN--NQDFKGSAGAPSVE 95
Query: 108 ALPRALVVGFVKTD------TEFQKKGETSGTTATFVIVDGWTVTVASVGDSRCILDTQG 161
+ + GF++ D +E + + SG+TA V++ + GDSR +L +
Sbjct: 96 NVKNGIRTGFLEIDEHMRVMSEKKHGADRSGSTAVGVLISPQHTYFINCGDSRGLL-CRN 154
Query: 162 GVVSLLTVDHRLEENVEERERVTASGGEV--GRLNIFGGNEVGPLRCWPGGLCLSRSIGD 219
V T DH+ N E+ER+ +GG V R+N G L +SR++GD
Sbjct: 155 RKVHFFTQDHK-PSNPLEKERIQNAGGSVMIQRVN--------------GSLAVSRALGD 199
Query: 220 TD---------VGEYIVPIPHVKQVKLSSAGGR-LIIASDGIWDTLSND 258
D + + P P V ++ S + +I+A DGIWD + N+
Sbjct: 200 FDYKCVHGKGPTEQLVSPEPEVHDIERSEEDDQFIILACDGIWDVMGNE 248
>P2CA_MOUSE (P49443) Protein phosphatase 2C alpha isoform (EC
3.1.3.16) (PP2C-alpha) (IA) (Protein phosphatase 1A)
Length = 382
Score = 70.1 bits (170), Expect = 1e-11
Identities = 67/229 (29%), Positives = 107/229 (46%), Gaps = 42/229 (18%)
Query: 54 DCHR-VPGDPS--TAFSVFAIFDGHNGISAAIYTKENLLNNVLSAIPQDISRDAW---LQ 107
D H V G PS +S FA++DGH G A Y E+LL+++ + QD A ++
Sbjct: 38 DAHTAVIGLPSGLETWSFFAVYDGHAGSQVAKYCCEHLLDHITN--NQDFRGSAGAPSVE 95
Query: 108 ALPRALVVGFVKTD------TEFQKKGETSGTTATFVIVDGWTVTVASVGDSRCILDTQG 161
+ + GF++ D +E + + SG+TA V++ + GDSR +L +
Sbjct: 96 NVKNGIRTGFLEIDEHMRVMSEKKHGADRSGSTAVGVLISPQHTYFINCGDSRGLL-CRN 154
Query: 162 GVVSLLTVDHRLEENVEERERVTASGGEV--GRLNIFGGNEVGPLRCWPGGLCLSRSIGD 219
V T DH+ N E+ER+ +GG V R+N G L +SR++GD
Sbjct: 155 RKVHFFTQDHK-PSNPLEKERIQNAGGSVMIQRVN--------------GSLAVSRALGD 199
Query: 220 TD---------VGEYIVPIPHVKQVKLSSAGGR-LIIASDGIWDTLSND 258
D + + P P V ++ S + +I+A DGIWD + N+
Sbjct: 200 FDYKCVHGKGPTEQLVSPEPEVHDIERSEEDDQFIILACDGIWDVMGNE 248
>P2CA_BOVIN (O62829) Protein phosphatase 2C alpha isoform (EC
3.1.3.16) (PP2C-alpha)
Length = 382
Score = 70.1 bits (170), Expect = 1e-11
Identities = 67/229 (29%), Positives = 107/229 (46%), Gaps = 42/229 (18%)
Query: 54 DCHR-VPGDPS--TAFSVFAIFDGHNGISAAIYTKENLLNNVLSAIPQDISRDAW---LQ 107
D H V G PS +S FA++DGH G A Y E+LL+++ + QD A ++
Sbjct: 38 DAHTAVIGLPSGLETWSFFAVYDGHAGSQVAKYCCEHLLDHITN--NQDFKGSAGAPSVE 95
Query: 108 ALPRALVVGFVKTD------TEFQKKGETSGTTATFVIVDGWTVTVASVGDSRCILDTQG 161
+ + GF++ D +E + + SG+TA V++ + GDSR +L +
Sbjct: 96 NVKNGIRTGFLEIDEHMRVMSEKKHGADRSGSTAVGVLISPQHTYFINCGDSRGLL-CRN 154
Query: 162 GVVSLLTVDHRLEENVEERERVTASGGEV--GRLNIFGGNEVGPLRCWPGGLCLSRSIGD 219
V T DH+ N E+ER+ +GG V R+N G L +SR++GD
Sbjct: 155 RKVYFFTQDHK-PSNPLEKERIQNAGGSVMIQRVN--------------GSLAVSRALGD 199
Query: 220 TD---------VGEYIVPIPHVKQVKLSSAGGR-LIIASDGIWDTLSND 258
D + + P P V ++ S + +I+A DGIWD + N+
Sbjct: 200 FDYKCVHGKGPTEQLVSPEPEVHDIERSEEDDQFIILACDGIWDVMGNE 248
>P2C3_SCHPO (Q09173) Protein phosphatase 2C homolog 3 (EC 3.1.3.16)
(PP2C-3)
Length = 414
Score = 69.7 bits (169), Expect = 1e-11
Identities = 65/233 (27%), Positives = 107/233 (45%), Gaps = 30/233 (12%)
Query: 69 FAIFDGHNGISAAIYTKENLLNNVLSAIPQDISRDAWLQALPRALVVGFVKTDTEFQKKG 128
FA++DGH G A + NL +L P D + ++ AL + + + Q
Sbjct: 58 FAVYDGHGGDKVAKWCGSNL-PQILEKNP-DFQKGDFVNALKSSFLNADKAILDDDQFHT 115
Query: 129 ETSGTTATFVIVDGWTVTVASVGDSRCILDTQGGVVSLLTVDHRLEENVEERERVTASGG 188
+ SG TAT V+ G + A+ GDSR +L ++ G+ L+ DH+ N E+ R+ A+GG
Sbjct: 116 DPSGCTATVVLRVGNKLYCANAGDSRTVLGSK-GIAKPLSADHK-PSNEAEKARICAAGG 173
Query: 189 --EVGRLNIFGGNEVGPLRCWPGGLCLSRSIGDTDV--------GEYIVPIPHVKQVKLS 238
+ GR+N G L LSR+IGD + + + +P V +++
Sbjct: 174 FVDFGRVN--------------GNLALSRAIGDFEFKNSNLEPEKQIVTALPDVVVHEIT 219
Query: 239 SAGGRLIIASDGIWD-TLSNDIAAMSCRGLPAELAAKLVVKEALRSRGLKDDT 290
+++A DGIWD S + RG+ A + + + E L + DT
Sbjct: 220 DDDEFVVLACDGIWDCKTSQQVIEFVRRGIVAGTSLEKIA-ENLMDNCIASDT 271
Database: sprot
Posted date: Nov 25, 2004 10:54 AM
Number of letters in database: 59,974,054
Number of sequences in database: 164,201
Lambda K H
0.317 0.136 0.404
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 51,996,334
Number of Sequences: 164201
Number of extensions: 2287216
Number of successful extensions: 5313
Number of sequences better than 10.0: 51
Number of HSP's better than 10.0 without gapping: 21
Number of HSP's successfully gapped in prelim test: 30
Number of HSP's that attempted gapping in prelim test: 5209
Number of HSP's gapped (non-prelim): 71
length of query: 428
length of database: 59,974,054
effective HSP length: 113
effective length of query: 315
effective length of database: 41,419,341
effective search space: 13047092415
effective search space used: 13047092415
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 67 (30.4 bits)
Medicago: description of AC144513.1