BLAST2 result
BLASTP 2.2.2 [Dec-14-2001]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= AC143341.5 + phase: 0
(485 letters)
Database: sprot
164,201 sequences; 59,974,054 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
PURA_ARATH (Q96529) Adenylosuccinate synthetase, chloroplast pre... 791 0.0
PURA_WHEAT (O24396) Adenylosuccinate synthetase, chloroplast pre... 713 0.0
PURA_MAIZE (O24578) Adenylosuccinate synthetase, chloroplast pre... 703 0.0
PURA_DICDI (P21900) Adenylosuccinate synthetase (EC 6.3.4.4) (IM... 493 e-139
PURA_SCHPO (Q02787) Adenylosuccinate synthetase (EC 6.3.4.4) (IM... 455 e-127
PURA_DROME (Q9Y0Y2) Adenylosuccinate synthetase (EC 6.3.4.4) (IM... 436 e-122
PURA_YEAST (P80210) Adenylosuccinate synthetase (EC 6.3.4.4) (IM... 436 e-122
PUA1_MOUSE (P28650) Adenylosuccinate synthetase, muscle isozyme ... 424 e-118
PUA1_HUMAN (Q8N142) Adenylosuccinate synthetase isozyme 1 (EC 6.... 421 e-117
PUA2_MOUSE (P46664) Adenylosuccinate synthetase, non-muscle isoz... 410 e-114
PUA2_HUMAN (P30520) Adenylosuccinate synthetase 2 (EC 6.3.4.4) (... 408 e-113
PURA_THETN (Q8R6T8) Adenylosuccinate synthetase (EC 6.3.4.4) (IM... 402 e-112
PURA_STRAW (Q82ER6) Adenylosuccinate synthetase (EC 6.3.4.4) (IM... 387 e-107
PURA_BIFLO (Q8G6T9) Adenylosuccinate synthetase (EC 6.3.4.4) (IM... 387 e-107
PURA_STRCO (Q9X8P6) Adenylosuccinate synthetase (EC 6.3.4.4) (IM... 384 e-106
PURA_LACLA (Q9CE93) Adenylosuccinate synthetase (EC 6.3.4.4) (IM... 382 e-106
PURA_CLOPE (Q8XH63) Adenylosuccinate synthetase (EC 6.3.4.4) (IM... 380 e-105
PURA_FUSNN (P58793) Adenylosuccinate synthetase (EC 6.3.4.4) (IM... 377 e-104
PURA_CHLTE (Q8KAK6) Adenylosuccinate synthetase (EC 6.3.4.4) (IM... 376 e-104
PURA_STRR6 (P65888) Adenylosuccinate synthetase (EC 6.3.4.4) (IM... 375 e-103
>PURA_ARATH (Q96529) Adenylosuccinate synthetase, chloroplast
precursor (EC 6.3.4.4) (IMP--aspartate ligase) (AdSS)
(AMPSase)
Length = 490
Score = 791 bits (2044), Expect = 0.0
Identities = 400/495 (80%), Positives = 437/495 (87%), Gaps = 15/495 (3%)
Query: 1 MNISSLRLDSHA-ICTHQPQRPFAFHNRFP-----RNVVVCAAKPVAPPPTKLAAADS-- 52
M++SSL LDS+ P +H R+P R+ V C+AK A + AADS
Sbjct: 1 MSLSSLTLDSNPRFAVGGP-----YHRRYPPLHHPRSFVSCSAKRPAVSASLSVAADSAA 55
Query: 53 --SLRRIESLSQVSGVLGCQWGDEGKGKLVDILAQHFQIVARCQGGANAGHTIYNAEGKK 110
SL RI SLSQVSGVLGCQWGDEGKGKLVDILAQHF IVARCQGGANAGHTIYN+EGKK
Sbjct: 56 TESLGRIGSLSQVSGVLGCQWGDEGKGKLVDILAQHFDIVARCQGGANAGHTIYNSEGKK 115
Query: 111 FALHLVPSGILNEDTLCVIGNGVVVHLPGLFQEIDNLESNGVSCKGRILISDRAHLLFDF 170
FALHLVPSGILNEDT CVIGNGVVVHLPGLF+EID LESNGVSCKGRIL+SDRAHLLFDF
Sbjct: 116 FALHLVPSGILNEDTTCVIGNGVVVHLPGLFKEIDGLESNGVSCKGRILVSDRAHLLFDF 175
Query: 171 HQTVDGLREAELSKSFIGTTKRGIGPCYSSKANRNGIRVGDLRYMETLPQKLDLLLSDAA 230
HQ VDGLRE+EL+KSFIGTTKRGIGP YSSK RNGIRVGDLR+M+TLPQKLDLLLSDAA
Sbjct: 176 HQEVDGLRESELAKSFIGTTKRGIGPAYSSKVIRNGIRVGDLRHMDTLPQKLDLLLSDAA 235
Query: 231 LRFKDFKYGPDVLREEVEKYKRYAERLEPYIADTVHVMNEAITQKKKVLVEGGQATMLDI 290
RF+ FKY P++LREEVE YKRYA+RLEPYI DTVH +N++I+QKKKVLVEGGQATMLDI
Sbjct: 236 ARFQGFKYTPEMLREEVEAYKRYADRLEPYITDTVHFINDSISQKKKVLVEGGQATMLDI 295
Query: 291 DFGTYPFVTSSSPSAGGICTGLGIAPRVIGDLVGVVKAYTTRVGSGPFPTEILGPGGDLL 350
DFGTYPFVTSSSPSAGGICTGLGIAP V+GDL+GVVKAYTTRVGSGPFPTE LG GGDLL
Sbjct: 296 DFGTYPFVTSSSPSAGGICTGLGIAPSVVGDLIGVVKAYTTRVGSGPFPTENLGTGGDLL 355
Query: 351 RFAGQEFGTTTGRPRRCGWLDIVALSYSCQINGFSSLNLTKLDVLSDLDEIQLGVSYKHA 410
R AGQEFGTTTGRPRRCGWLDIVAL +SCQINGF+SLNLTKLDVLSDL+EIQLGV+YK +
Sbjct: 356 RLAGQEFGTTTGRPRRCGWLDIVALKFSCQINGFASLNLTKLDVLSDLNEIQLGVAYKRS 415
Query: 411 DGTPVQSFPSDLRLLEQLKVEYESLPGWKTDISSIRNYSDLPRAAQLYVERIEELVGVPI 470
DGTPV+SFP DLRLLE+L VEYE LPGWK+DISS+RNYSDLP+AAQ YVERIEELVGVPI
Sbjct: 416 DGTPVKSFPGDLRLLEELHVEYEVLPGWKSDISSVRNYSDLPKAAQQYVERIEELVGVPI 475
Query: 471 HYIGVGPGRDALIFK 485
HYIG+GPGRDALI+K
Sbjct: 476 HYIGIGPGRDALIYK 490
>PURA_WHEAT (O24396) Adenylosuccinate synthetase, chloroplast
precursor (EC 6.3.4.4) (IMP--aspartate ligase) (AdSS)
(AMPSase) (Fragment)
Length = 476
Score = 713 bits (1841), Expect = 0.0
Identities = 349/449 (77%), Positives = 389/449 (85%), Gaps = 4/449 (0%)
Query: 41 APPPTKLAA----ADSSLRRIESLSQVSGVLGCQWGDEGKGKLVDILAQHFQIVARCQGG 96
AP P +A AD + R+ SLSQVSGVLG QWGDEGKGKLVD+LA F IVARCQGG
Sbjct: 28 APAPAAASALAVEADPAADRVSSLSQVSGVLGSQWGDEGKGKLVDVLAPRFDIVARCQGG 87
Query: 97 ANAGHTIYNAEGKKFALHLVPSGILNEDTLCVIGNGVVVHLPGLFQEIDNLESNGVSCKG 156
ANAGHTIYN+EGKKFALHLVPSGIL+E TLCV+GNG V+H+PG F EID L+SNGVSC G
Sbjct: 88 ANAGHTIYNSEGKKFALHLVPSGILHEGTLCVVGNGAVIHVPGFFGEIDGLQSNGVSCDG 147
Query: 157 RILISDRAHLLFDFHQTVDGLREAELSKSFIGTTKRGIGPCYSSKANRNGIRVGDLRYME 216
RIL+SDRAHLLFD HQTVDGLREAEL+ SFIGTTKRGIGPCYSSK RNG+RV DLR+M+
Sbjct: 148 RILVSDRAHLLFDLHQTVDGLREAELANSFIGTTKRGIGPCYSSKVTRNGLRVCDLRHMD 207
Query: 217 TLPQKLDLLLSDAALRFKDFKYGPDVLREEVEKYKRYAERLEPYIADTVHVMNEAITQKK 276
T KLD+L DAA RF+ FKY +L+EEVE+YKR+AERLEP+IADTVHV+NE+I QKK
Sbjct: 208 TFGDKLDVLFEDAAARFEGFKYSKGMLKEEVERYKRFAERLEPFIADTVHVLNESIRQKK 267
Query: 277 KVLVEGGQATMLDIDFGTYPFVTSSSPSAGGICTGLGIAPRVIGDLVGVVKAYTTRVGSG 336
K+LVEGGQATMLDIDFGTYPFVTSSSPSAGGICTGLGIAPRVIGDL+GVVKAYTTRVGSG
Sbjct: 268 KILVEGGQATMLDIDFGTYPFVTSSSPSAGGICTGLGIAPRVIGDLIGVVKAYTTRVGSG 327
Query: 337 PFPTEILGPGGDLLRFAGQEFGTTTGRPRRCGWLDIVALSYSCQINGFSSLNLTKLDVLS 396
PFPTE+LG GD+LR AG EFGTTTGRPRRCGWLDIVAL Y C INGFSSLNLTKLDVLS
Sbjct: 328 PFPTELLGEEGDVLRKAGMEFGTTTGRPRRCGWLDIVALKYCCDINGFSSLNLTKLDVLS 387
Query: 397 DLDEIQLGVSYKHADGTPVQSFPSDLRLLEQLKVEYESLPGWKTDISSIRNYSDLPRAAQ 456
L EI+LGVSY DG +QSFP DL LEQ++V YE LPGW +DISS+R+YS+LP+AA+
Sbjct: 388 GLPEIKLGVSYNQMDGEKLQSFPGDLDTLEQVQVNYEVLPGWDSDISSVRSYSELPQAAR 447
Query: 457 LYVERIEELVGVPIHYIGVGPGRDALIFK 485
YVERIEEL GVP+HYIGVGPGRDALI+K
Sbjct: 448 RYVERIEELAGVPVHYIGVGPGRDALIYK 476
>PURA_MAIZE (O24578) Adenylosuccinate synthetase, chloroplast
precursor (EC 6.3.4.4) (IMP--aspartate ligase) (AdSS)
(AMPSase)
Length = 484
Score = 703 bits (1814), Expect = 0.0
Identities = 346/468 (73%), Positives = 391/468 (82%), Gaps = 5/468 (1%)
Query: 18 PQRPFAFHNRFPRNVVVCAAKPVAPPPTKLAAADSSLRRIESLSQVSGVLGCQWGDEGKG 77
P P A FP+ A PV + AA + R+ SL+QVSGVLG QWGDEGKG
Sbjct: 22 PAGPAAQSVHFPK-----ARLPVPAAVSAATAAVHAEDRVSSLTQVSGVLGSQWGDEGKG 76
Query: 78 KLVDILAQHFQIVARCQGGANAGHTIYNAEGKKFALHLVPSGILNEDTLCVIGNGVVVHL 137
KLVD+LA F IVARCQGGANAGHTIYN+EGKKFALHLVPSGIL+E TLCV+GNG V+H+
Sbjct: 77 KLVDVLAPRFDIVARCQGGANAGHTIYNSEGKKFALHLVPSGILHEGTLCVVGNGAVIHV 136
Query: 138 PGLFQEIDNLESNGVSCKGRILISDRAHLLFDFHQTVDGLREAELSKSFIGTTKRGIGPC 197
PG F EID LESNGV C GRIL+SDRAHLLFD HQ VDGLREAEL SFIGTTKRGIGPC
Sbjct: 137 PGFFGEIDGLESNGVRCGGRILVSDRAHLLFDLHQAVDGLREAELENSFIGTTKRGIGPC 196
Query: 198 YSSKANRNGIRVGDLRYMETLPQKLDLLLSDAALRFKDFKYGPDVLREEVEKYKRYAERL 257
YSSK RNG+RV DLR+M+T KLD+L DAA RF+ F+Y +L+EEVE+YK++A+RL
Sbjct: 197 YSSKVTRNGLRVCDLRHMDTFGDKLDILFKDAASRFQGFQYSKSLLKEEVERYKKFADRL 256
Query: 258 EPYIADTVHVMNEAITQKKKVLVEGGQATMLDIDFGTYPFVTSSSPSAGGICTGLGIAPR 317
EP+IADTVHV+NE+I QKKK+LVEGGQATMLDIDFGTYPFVTSSSPSAGGICTGLGIAPR
Sbjct: 257 EPFIADTVHVLNESIKQKKKILVEGGQATMLDIDFGTYPFVTSSSPSAGGICTGLGIAPR 316
Query: 318 VIGDLVGVVKAYTTRVGSGPFPTEILGPGGDLLRFAGQEFGTTTGRPRRCGWLDIVALSY 377
IGDL+GVVKAYT+RVGSGPFPTE+ G GD LR AG EFGTTTGRPRRCGWLDIVAL +
Sbjct: 317 AIGDLIGVVKAYTSRVGSGPFPTELFGEEGDRLRKAGMEFGTTTGRPRRCGWLDIVALKH 376
Query: 378 SCQINGFSSLNLTKLDVLSDLDEIQLGVSYKHADGTPVQSFPSDLRLLEQLKVEYESLPG 437
SCQINGFSSLNLTKLDVLS L EI++GVSY DG +QSFP DL LEQ++V YE LPG
Sbjct: 377 SCQINGFSSLNLTKLDVLSGLSEIKVGVSYTQTDGQKLQSFPGDLDTLEQVQVNYEVLPG 436
Query: 438 WKTDISSIRNYSDLPRAAQLYVERIEELVGVPIHYIGVGPGRDALIFK 485
W++DISS+R Y +LP+AA+LYVERIEELVGVP+HYIGVGPGRDALI+K
Sbjct: 437 WQSDISSVRRYDELPQAARLYVERIEELVGVPVHYIGVGPGRDALIYK 484
>PURA_DICDI (P21900) Adenylosuccinate synthetase (EC 6.3.4.4)
(IMP--aspartate ligase) (AdSS) (AMPSase)
Length = 427
Score = 493 bits (1269), Expect = e-139
Identities = 245/422 (58%), Positives = 309/422 (73%), Gaps = 9/422 (2%)
Query: 66 VLGCQWGDEGKGKLVDILAQHFQIVARCQGGANAGHTIYNAEGKKFALHLVPSGILNEDT 125
++G QWGDEGKGKLVDIL+Q F +VARCQGGANAGHTI +GKK ALHL+PSGILNE
Sbjct: 5 IIGSQWGDEGKGKLVDILSQQFDVVARCQGGANAGHTIV-VDGKKIALHLIPSGILNEKA 63
Query: 126 LCVIGNGVVVHLPGLFQEIDNLESNGVSCKGRILISDRAHLLFDFHQTVDGLREAELSKS 185
C++GNG+V+HLP F+E+ L+ G++ KGR+ +SDRAHL+FD HQ +D ++EAELS
Sbjct: 64 SCILGNGMVIHLPTFFKEVQGLQDKGINYKGRLFVSDRAHLVFDLHQMIDAMKEAELSNG 123
Query: 186 F----IGTTKRGIGPCYSSKANRNGIRVGDLRYMETLPQKLDLLLSDAALRFKDFKYGPD 241
IGTTKRGIGPCYSSKA+R G+RV DL E + L+ + RF F+Y +
Sbjct: 124 TSNDSIGTTKRGIGPCYSSKASRGGLRVCDLYSPEHFRKTFTRLVENKHKRFGSFEYDVE 183
Query: 242 VLREEVEKYKRYAERLEPYIADTVHVMNEAITQKKKVLVEGGQATMLDIDFGTYPFVTSS 301
E+++Y+ +AE L+P++ D+V+ +N+A KKVL+EG Q+TMLD+DFG YP+VTSS
Sbjct: 184 A---ELKRYQEFAEMLKPFVIDSVYYLNQAFKDGKKVLIEGAQSTMLDLDFGCYPYVTSS 240
Query: 302 SPSAGGICTGLGIAPRVIGDLVGVVKAYTTRVGSGPFPTEILGPGGDLLRFAGQEFGTTT 361
+ S GG CTGLGI+P + +GVVKAYTT+VGSGPFPTE GD LR AG EFGTTT
Sbjct: 241 ASSVGGACTGLGISPNKVVTQIGVVKAYTTKVGSGPFPTEQNDHVGDSLRKAGSEFGTTT 300
Query: 362 GRPRRCGWLDIVALSYSCQINGFSSLNLTKLDVLSDLDEIQLGVSYKHADGTPVQSFPSD 421
GRPRR GWLD V L Y+ IN F+ LNLTKLDVLSD +EI++GV YK+ G ++SFP+
Sbjct: 301 GRPRRIGWLDAVVLRYTSMINDFTRLNLTKLDVLSDFEEIKIGVDYKY-KGETIKSFPAS 359
Query: 422 LRLLEQLKVEYESLPGWKTDISSIRNYSDLPRAAQLYVERIEELVGVPIHYIGVGPGRDA 481
L L Q +V YES PGWK D+S + Y LP A+ Y++RIEELVGVPI YIGVG R
Sbjct: 360 LETLAQCEVVYESFPGWKCDLSHVTEYDQLPIQAKNYIKRIEELVGVPIVYIGVGVERKN 419
Query: 482 LI 483
LI
Sbjct: 420 LI 421
>PURA_SCHPO (Q02787) Adenylosuccinate synthetase (EC 6.3.4.4)
(IMP--aspartate ligase) (AdSS) (AMPSase)
Length = 434
Score = 455 bits (1171), Expect = e-127
Identities = 224/423 (52%), Positives = 299/423 (69%), Gaps = 5/423 (1%)
Query: 63 VSGVLGCQWGDEGKGKLVDILAQHFQIVARCQGGANAGHTIYNAEGKKFALHLVPSGILN 122
++ VLG QWGDEGKGKLVDIL + + ARCQGG NAGHTI A G + H++PSG++N
Sbjct: 16 ITVVLGSQWGDEGKGKLVDILCDNVDVCARCQGGNNAGHTIV-ANGVTYDFHILPSGLVN 74
Query: 123 EDTLCVIGNGVVVHLPGLFQEIDNLESNGVSCKGRILISDRAHLLFDFHQTVDGLREAEL 182
+IG+GVVV+LP F E++ LE G+ C+ RI ISDRAHL+FD+HQ D L EAEL
Sbjct: 75 PKCQNLIGSGVVVYLPAFFSELEKLEQKGLKCRDRIFISDRAHLVFDYHQRADALNEAEL 134
Query: 183 SKSFIGTTKRGIGPCYSSKANRNGIRVGDLRYMETLPQKLDLLLSDAALRFKDFKYGPDV 242
K IGTT +GIGP YS+KA R+GIRV L + + ++D R+ F+Y +
Sbjct: 135 GKQSIGTTGKGIGPAYSTKATRSGIRVHHLYHWAEFEARYRKNVADLQKRYGAFEYDVEA 194
Query: 243 LREEVEKYKRYAERLEPYIADTVHVMNEAITQKKKVLVEGGQATMLDIDFGTYPFVTSSS 302
E+ +YK A+RL+P++ D V M EA+ KK++LVEG A MLD+DFGTYPFVTSS+
Sbjct: 195 ---ELIRYKELAQRLKPFVIDAVAFMYEALQSKKRILVEGANALMLDLDFGTYPFVTSSN 251
Query: 303 PSAGGICTGLGIAPRVIGDLVGVVKAYTTRVGSGPFPTEILGPGGDLLRFAGQEFGTTTG 362
+ GG+CTGLG+ P+ I + +GVVKAYTTRVG+GPFPTE L GD L+ G+E G TTG
Sbjct: 252 TTVGGVCTGLGVPPQRIANSIGVVKAYTTRVGAGPFPTEQLNEIGDHLQSVGREVGVTTG 311
Query: 363 RPRRCGWLDIVALSYSCQINGFSSLNLTKLDVLSDLDEIQLGVSYKHADGTPVQSFPSDL 422
R RRCGWLD+V + YS ING++SLNLTKLD+L LDEI++ V+Y +G +++FP+DL
Sbjct: 312 RKRRCGWLDLVVVKYSTMINGYTSLNLTKLDILDALDEIKVAVAY-IINGKRIETFPADL 370
Query: 423 RLLEQLKVEYESLPGWKTDISSIRNYSDLPRAAQLYVERIEELVGVPIHYIGVGPGRDAL 482
LE+ ++ YE+ PGWK + I ++ +P A+ Y+E IE+ VGVPI +IGVGPGRD +
Sbjct: 371 DSLEEAEIVYETFPGWKVPTTGITHWDQMPENAKKYIEFIEKFVGVPITFIGVGPGRDEM 430
Query: 483 IFK 485
+ K
Sbjct: 431 LVK 433
>PURA_DROME (Q9Y0Y2) Adenylosuccinate synthetase (EC 6.3.4.4)
(IMP--aspartate ligase) (AdSS) (AMPSase)
Length = 447
Score = 436 bits (1122), Expect = e-122
Identities = 218/425 (51%), Positives = 291/425 (68%), Gaps = 6/425 (1%)
Query: 61 SQVSGVLGCQWGDEGKGKLVDILAQHFQIVARCQGGANAGHTIYNAEGKKFALHLVPSGI 120
S+V VLG QWGDEGKGK+VD+LA IV RCQGG NAGHT+ A G +F HL+PSG+
Sbjct: 24 SKVDVVLGAQWGDEGKGKVVDMLASDVDIVCRCQGGNNAGHTVV-ANGTEFDFHLLPSGV 82
Query: 121 LNEDTLCVIGNGVVVHLPGLFQEIDNLESNGVS-CKGRILISDRAHLLFDFHQTVDGLRE 179
+NE + VIGNGVV+HLP LF E+ E+ G+ + R++ISDRAHL+FDFHQ VDG++E
Sbjct: 83 VNEKCVSVIGNGVVIHLPSLFDEVLKNEAKGLQHLENRLIISDRAHLVFDFHQHVDGMQE 142
Query: 180 AELSKSFIGTTKRGIGPCYSSKANRNGIRVGDLRY-METLPQKLDLLLSDAALRFKDFKY 238
AE +GTTK+GIGP YSSKA RNGIRVG+L +K +++ F
Sbjct: 143 AEKGGKSLGTTKKGIGPAYSSKATRNGIRVGELLGDFNLFSEKFKSIVATHVRLFPSINV 202
Query: 239 GPDVLREEVEKYKRYAERLEPYIADTVHVMNEAITQKKKVLVEGGQATMLDIDFGTYPFV 298
+ E+ +YK YA+++ PY+ DT+ ++ A+ K +LVEG A MLDIDFGTYP+V
Sbjct: 203 DVEA---ELARYKDYADKVRPYVKDTICFLHTALRNGKTILVEGANAAMLDIDFGTYPYV 259
Query: 299 TSSSPSAGGICTGLGIAPRVIGDLVGVVKAYTTRVGSGPFPTEILGPGGDLLRFAGQEFG 358
TSS+ S GG+ TGLG+ P+ IG+++GVVKAYTTRVG GPFPTE L GDLL+ G E G
Sbjct: 260 TSSNCSIGGVLTGLGLPPQTIGEVIGVVKAYTTRVGDGPFPTEQLNDIGDLLQTRGFEVG 319
Query: 359 TTTGRPRRCGWLDIVALSYSCQINGFSSLNLTKLDVLSDLDEIQLGVSYKHADGTPVQSF 418
TT R RRCGWLDI L Y+ +NG++ + LTKLD+L L EI++ V+YK +G + F
Sbjct: 320 VTTKRKRRCGWLDIPLLKYTSLVNGYTCICLTKLDILDTLPEIKVAVAYKKPNGEKLDHF 379
Query: 419 PSDLRLLEQLKVEYESLPGWKTDISSIRNYSDLPRAAQLYVERIEELVGVPIHYIGVGPG 478
P + L ++VEY LPGW+T +RN+ +LP AQ YV +E + VP+ ++GVG G
Sbjct: 380 PGTIAELGNIEVEYAVLPGWQTSTEEVRNFKELPENAQSYVRLLESELSVPVRWVGVGKG 439
Query: 479 RDALI 483
R+++I
Sbjct: 440 RESII 444
>PURA_YEAST (P80210) Adenylosuccinate synthetase (EC 6.3.4.4)
(IMP--aspartate ligase) (AdSS) (AMPSase)
Length = 432
Score = 436 bits (1121), Expect = e-122
Identities = 222/434 (51%), Positives = 296/434 (68%), Gaps = 16/434 (3%)
Query: 63 VSGVLGCQWGDEGKGKLVDILAQHFQIVARCQGGANAGHTIYNAEGKKFALHLVPSGILN 122
V+ VLG QWGDEGKGKLVD+L + IVARC GG NAGHTI +G K+ H++PSG++N
Sbjct: 1 VNVVLGSQWGDEGKGKLVDLLVGKYDIVARCAGGNNAGHTIV-VDGVKYDFHMLPSGLVN 59
Query: 123 EDTLCVIGNGVVVHLPGLFQEIDNLESNGV-SCKGRILISDRAHLLFDFHQTVDGLREAE 181
+ ++GNGVV+H+P F+E++ LE+ G+ + + R+ +S RAHL+FDFHQ D LRE E
Sbjct: 60 PNCQNLLGNGVVIHVPSFFKELETLEAKGLKNARSRLFVSSRAHLVFDFHQVTDKLRELE 119
Query: 182 LSKSF-----IGTTKRGIGPCYSSKANRNGIRVGDL-----RYMETLPQKLDLLLSDAAL 231
LS IGTT +GIGP YS+KA+R+G+RV L E + LL
Sbjct: 120 LSGRSKDGKNIGTTGKGIGPTYSTKASRSGLRVHHLVNDQPGAWEEFVARYKRLLETRRQ 179
Query: 232 RFKDFKYGPDVLREEVEKYKRYAERLEPYIADTVHVMNEAITQKKKVLVEGGQATMLDID 291
R+ DF+Y ++ +YK+ E+L+P++ D+V M+ AI KKK+LVEG A MLDID
Sbjct: 180 RYGDFEYD---FEAKLAEYKKLREQLKPFVVDSVVFMHNAIEAKKKILVEGANALMLDID 236
Query: 292 FGTYPFVTSSSPSAGGICTGLGIAPRVIGDLVGVVKAYTTRVGSGPFPTEILGPGGDLLR 351
FGTYP+VTSS+ GG+ TGLGI PR I ++ GVVKAYTTRVG GPFPTE L G+ L+
Sbjct: 237 FGTYPYVTSSNTGIGGVLTGLGIPPRTIDEIYGVVKAYTTRVGEGPFPTEQLNENGEKLQ 296
Query: 352 FAGQEFGTTTGRPRRCGWLDIVALSYSCQINGFSSLNLTKLDVLSDLDEIQLGVSYKHAD 411
G EFG TTGR RRCGWLD+V L YS ING++SLN+TKLDVL EI +G+SY
Sbjct: 297 TIGAEFGVTTGRKRRCGWLDLVVLKYSTLINGYTSLNITKLDVLDTFKEIPVGISYS-IQ 355
Query: 412 GTPVQSFPSDLRLLEQLKVEYESLPGWKTDISSIRNYSDLPRAAQLYVERIEELVGVPIH 471
G + FP DL +L +++VEY+ LPGW DI+ I Y DLP A+ Y++ IE+ VGVP+
Sbjct: 356 GKKLDLFPEDLNILGKVEVEYKVLPGWDQDITKITKYEDLPENAKKYLKYIEDFVGVPVE 415
Query: 472 YIGVGPGRDALIFK 485
++G GP R++++ K
Sbjct: 416 WVGTGPARESMLHK 429
>PUA1_MOUSE (P28650) Adenylosuccinate synthetase, muscle isozyme (EC
6.3.4.4) (IMP--aspartate ligase 1) (AdSS 1) (AMPSase 1)
Length = 457
Score = 424 bits (1089), Expect = e-118
Identities = 226/440 (51%), Positives = 304/440 (68%), Gaps = 33/440 (7%)
Query: 61 SQVSGVLGCQWGDEGKGKLVDILAQHFQIVARCQGGANAGHTIYNAEGKKFALHLVPSGI 120
S+V+ VLG QWGDEGKGK+VD+LA IV+RCQGG NAGHT+ +GK++ HL+PSGI
Sbjct: 31 SRVTVVLGAQWGDEGKGKVVDLLATDADIVSRCQGGNNAGHTVV-VDGKEYDFHLLPSGI 89
Query: 121 LNEDTLCVIGNGVVVHLPGLFQEIDNLESNGVS-CKGRILISDRAHLLFDFHQTVDGL-- 177
+N + IGNGVV+HLPGLF+E + E G+ + R++ISDRAHL+FDFHQ VDGL
Sbjct: 90 INTKAVSFIGNGVVIHLPGLFEEAEKNEKKGLKDWEKRLIISDRAHLVFDFHQAVDGLQE 149
Query: 178 --REAELSKSFIGTTKRGIGPCYSSKANRNGIRVGDLRYMETLPQKLDLLLSDA---ALR 232
R+A+ K+ IGTTK+GIGP YSSKA R G+R+ DL LSD + R
Sbjct: 150 VQRQAQEGKN-IGTTKKGIGPTYSSKAARTGLRICDL-------------LSDFDEFSAR 195
Query: 233 FKDFKYGPDVL--------REEVEKYKRYAERLEPYIADTVHVMNEAIT-QKKKVLVEGG 283
FK+ + + ++++ K +AER+ P + D V+ M EA+ KKVLVEG
Sbjct: 196 FKNLAHQHQSMFPTLEIDVEGQLKRLKGFAERIRPMVRDGVYFMYEALHGPPKKVLVEGA 255
Query: 284 QATMLDIDFGTYPFVTSSSPSAGGICTGLGIAPRVIGDLVGVVKAYTTRVGSGPFPTEIL 343
A +LDIDFGTYPFVTSS+ + GG+CTGLGI P+ IGD+ GVVKAYTTRVG G FPTE +
Sbjct: 256 NAALLDIDFGTYPFVTSSNCTVGGVCTGLGIPPQNIGDVYGVVKAYTTRVGIGAFPTEQI 315
Query: 344 GPGGDLLRFAGQEFGTTTGRPRRCGWLDIVALSYSCQINGFSSLNLTKLDVLSDLDEIQL 403
GDLL+ G E+G TTGR RRCGWLD++ L Y+ +NGF++L LTKLD+L L EI++
Sbjct: 316 NEIGDLLQNRGHEWGVTTGRKRRCGWLDLMILRYAHMVNGFTALALTKLDILDVLSEIKV 375
Query: 404 GVSYKHADGTPVQSFPSDLRLLEQLKVEYESLPGWKTDISSIRNYSDLPRAAQLYVERIE 463
G+SYK +G + FP++ +L++++VEYE+LPGWK D + R + DLP AQ YV +E
Sbjct: 376 GISYK-LNGKRIPYFPANQEILQKVEVEYETLPGWKADTTGARKWEDLPPQAQSYVRFVE 434
Query: 464 ELVGVPIHYIGVGPGRDALI 483
+GV + ++GVG R+++I
Sbjct: 435 NHMGVAVKWVGVGKSRESMI 454
>PUA1_HUMAN (Q8N142) Adenylosuccinate synthetase isozyme 1 (EC
6.3.4.4) (IMP--aspartate ligase 1) (AdSS 1) (AMPSase 1)
Length = 457
Score = 421 bits (1081), Expect = e-117
Identities = 219/430 (50%), Positives = 299/430 (68%), Gaps = 13/430 (3%)
Query: 61 SQVSGVLGCQWGDEGKGKLVDILAQHFQIVARCQGGANAGHTIYNAEGKKFALHLVPSGI 120
S+V+ VLG QWGDEGKGK+VD+LA I++RCQGG NAGHT+ +GK++ HL+PSGI
Sbjct: 31 SRVTVVLGAQWGDEGKGKVVDLLATDADIISRCQGGNNAGHTVV-VDGKEYDFHLLPSGI 89
Query: 121 LNEDTLCVIGNGVVVHLPGLFQEIDNLESNGVS-CKGRILISDRAHLLFDFHQTVDGL-- 177
+N + IGNGVV+HLPGLF+E + E G+ + R++ISDRAHL+FDFHQ VDGL
Sbjct: 90 INTKAVSFIGNGVVIHLPGLFEEAEKNEKKGLKDWEKRLIISDRAHLVFDFHQAVDGLQE 149
Query: 178 --REAELSKSFIGTTKRGIGPCYSSKANRNGIRVGDLRY-METLPQKLDLLLSDAALRFK 234
R+A+ K+ IGTTK+GIGP YSSKA R G+R+ DL + + L F
Sbjct: 150 VQRQAQEGKN-IGTTKKGIGPTYSSKAARTGLRICDLLSDFDEFSSRFKNLAHQHQSMFP 208
Query: 235 DFKYGPDVLREEVEKYKRYAERLEPYIADTVHVMNEAIT-QKKKVLVEGGQATMLDIDFG 293
+ + ++++ K +AER+ P + D V+ M EA+ KK+LVEG A +LDIDFG
Sbjct: 209 TLEID---IEGQLKRLKGFAERIRPMVRDGVYFMYEALHGPPKKILVEGANAALLDIDFG 265
Query: 294 TYPFVTSSSPSAGGICTGLGIAPRVIGDLVGVVKAYTTRVGSGPFPTEILGPGGDLLRFA 353
TYPFVTSS+ + GG+CTGLGI P+ IGD+ GVVKAYTTRVG G FPTE + G LL+
Sbjct: 266 TYPFVTSSNCTVGGVCTGLGIPPQNIGDVYGVVKAYTTRVGIGAFPTEQINEIGGLLQTR 325
Query: 354 GQEFGTTTGRPRRCGWLDIVALSYSCQINGFSSLNLTKLDVLSDLDEIQLGVSYKHADGT 413
G E+G TTGR RRCGWLD++ L Y+ +NGF++L LTKLD+L L E+++GVSYK +G
Sbjct: 326 GHEWGVTTGRKRRCGWLDLMILRYAHMVNGFTALALTKLDILDVLGEVKVGVSYK-LNGK 384
Query: 414 PVQSFPSDLRLLEQLKVEYESLPGWKTDISSIRNYSDLPRAAQLYVERIEELVGVPIHYI 473
+ FP++ +L++++VEYE+LPGWK D + R + DLP AQ Y+ +E VGV + ++
Sbjct: 385 RIPYFPANQEMLQKVEVEYETLPGWKADTTGARRWEDLPPQAQNYIRFVENHVGVAVKWV 444
Query: 474 GVGPGRDALI 483
GVG R+++I
Sbjct: 445 GVGKSRESMI 454
>PUA2_MOUSE (P46664) Adenylosuccinate synthetase, non-muscle isozyme
(EC 6.3.4.4) (IMP--aspartate ligase 2) (AdSS 2) (AMPSase
2)
Length = 456
Score = 410 bits (1054), Expect = e-114
Identities = 216/452 (47%), Positives = 305/452 (66%), Gaps = 14/452 (3%)
Query: 41 APPPTKLAAADSSLRRIESL-SQVSGVLGCQWGDEGKGKLVDILAQHFQIVARCQGGANA 99
+P T L D R S ++V+ VLG QWGDEGKGK+VD+LAQ IV RCQGG NA
Sbjct: 7 SPAATSLPNGDCGRPRARSGGNRVTVVLGAQWGDEGKGKVVDLLAQDADIVCRCQGGNNA 66
Query: 100 GHTIYNAEGKKFALHLVPSGILNEDTLCVIGNGVVVHLPGLFQEIDNLESNGVSCKG--- 156
GHT+ + ++ HL+PSGI+N + IGNGVV+HLPGLF+E + G G
Sbjct: 67 GHTVV-VDSVEYDFHLLPSGIINPNVTAFIGNGVVIHLPGLFEEAEKNVQKGKGLDGWEK 125
Query: 157 RILISDRAHLLFDFHQTVDGLREAELSKSF---IGTTKRGIGPCYSSKANRNGIRVGDL- 212
R++ISDRAH++FDFHQ DG++E + + +GTTK+GI P YSSKA R+G+R+ DL
Sbjct: 126 RLIISDRAHIVFDFHQAADGIQEQQRQEQAGKNLGTTKKGIRPVYSSKAARSGLRMCDLV 185
Query: 213 RYMETLPQKLDLLLSDAALRFKDFKYGPDVLREEVEKYKRYAERLEPYIADTVHVMNEAI 272
+ ++ +L + + + + E+++ K Y ER++P + D V+ + EA+
Sbjct: 186 SDFDGFSERFKVLTNQYKSIYPTLEID---IEGELQQLKGYMERIKPMVKDGVYFLYEAL 242
Query: 273 T-QKKKVLVEGGQATMLDIDFGTYPFVTSSSPSAGGICTGLGIAPRVIGDLVGVVKAYTT 331
KK+LVEG A +LDIDFGTYPFVTSS+ + GG+CTGLG+ P+ +G++ GVVKAYTT
Sbjct: 243 HGPPKKILVEGANAALLDIDFGTYPFVTSSNCTVGGVCTGLGMPPQNVGEVYGVVKAYTT 302
Query: 332 RVGSGPFPTEILGPGGDLLRFAGQEFGTTTGRPRRCGWLDIVALSYSCQINGFSSLNLTK 391
RVG G FPTE G+LL+ G+EFG TTGR RRCGWLD+V+L Y+ INGF++L LTK
Sbjct: 303 RVGIGAFPTEQDNEIGELLQTRGREFGVTTGRKRRCGWLDLVSLKYAHMINGFTALALTK 362
Query: 392 LDVLSDLDEIQLGVSYKHADGTPVQSFPSDLRLLEQLKVEYESLPGWKTDISSIRNYSDL 451
LD+L EI++GV+YK DG + FP++ +L +++V+Y++LPGW TDIS+ R + +L
Sbjct: 363 LDILDMFTEIKVGVAYK-LDGETIPHFPANQEVLNKVEVQYKTLPGWNTDISNARTFKEL 421
Query: 452 PRAAQLYVERIEELVGVPIHYIGVGPGRDALI 483
P AQ YV IE+ + +P+ +IGVG R+++I
Sbjct: 422 PVNAQNYVRFIEDELQIPVKWIGVGKSRESMI 453
>PUA2_HUMAN (P30520) Adenylosuccinate synthetase 2 (EC 6.3.4.4)
(IMP--aspartate ligase 2) (AdSS 2) (AMPSase 2)
Length = 456
Score = 408 bits (1048), Expect = e-113
Identities = 210/431 (48%), Positives = 298/431 (68%), Gaps = 13/431 (3%)
Query: 61 SQVSGVLGCQWGDEGKGKLVDILAQHFQIVARCQGGANAGHTIYNAEGKKFALHLVPSGI 120
++V+ VLG QWGDEGKGK+VD+LAQ IV RCQGG NAGHT+ + ++ HL+PSGI
Sbjct: 28 NRVTVVLGAQWGDEGKGKVVDLLAQDADIVCRCQGGNNAGHTVV-VDSVEYDFHLLPSGI 86
Query: 121 LNEDTLCVIGNGVVVHLPGLFQEIDNLESNGVSCKG---RILISDRAHLLFDFHQTVDGL 177
+N + IGNGVV+HLPGLF+E + G +G R++ISDRAH++FDFHQ DG+
Sbjct: 87 INPNVTAFIGNGVVIHLPGLFEEAEKNVQKGKGLEGWEKRLIISDRAHIVFDFHQAADGI 146
Query: 178 REAELSKSF---IGTTKRGIGPCYSSKANRNGIRVGDL-RYMETLPQKLDLLLSDAALRF 233
+E + + +GTTK+GIGP YSSKA R+G+R+ DL + ++ +L + +
Sbjct: 147 QEQQRQEQAGKNLGTTKKGIGPVYSSKAARSGLRMCDLVSDFDGFSERFKVLANQYKSIY 206
Query: 234 KDFKYGPDVLREEVEKYKRYAERLEPYIADTVHVMNEAIT-QKKKVLVEGGQATMLDIDF 292
+ + E++K K Y E+++P + D V+ + EA+ KK+LVEG A +LDIDF
Sbjct: 207 PTLEID---IEGELQKLKGYMEKIKPMVRDGVYFLYEALHGPPKKILVEGANAALLDIDF 263
Query: 293 GTYPFVTSSSPSAGGICTGLGIAPRVIGDLVGVVKAYTTRVGSGPFPTEILGPGGDLLRF 352
GTYPFVTSS+ + GG+CTGLG+ P+ +G++ GVVKAYTTRVG G FPTE G+LL+
Sbjct: 264 GTYPFVTSSNCTVGGVCTGLGMPPQNVGEVYGVVKAYTTRVGIGAFPTEQDNEIGELLQT 323
Query: 353 AGQEFGTTTGRPRRCGWLDIVALSYSCQINGFSSLNLTKLDVLSDLDEIQLGVSYKHADG 412
G+EFG TTGR RRCGWLD+V L Y+ INGF++L LTKLD+L EI++GV+YK DG
Sbjct: 324 RGREFGVTTGRKRRCGWLDLVLLKYAHMINGFTALALTKLDILDMFTEIKVGVAYK-LDG 382
Query: 413 TPVQSFPSDLRLLEQLKVEYESLPGWKTDISSIRNYSDLPRAAQLYVERIEELVGVPIHY 472
+ P++ +L +++V+Y++LPGW TDIS+ R + +LP AQ YV IE+ + +P+ +
Sbjct: 383 EIIPHIPANQEVLNKVEVQYKTLPGWNTDISNARAFKELPVNAQNYVRFIEDELQIPVKW 442
Query: 473 IGVGPGRDALI 483
IGVG R+++I
Sbjct: 443 IGVGKSRESMI 453
>PURA_THETN (Q8R6T8) Adenylosuccinate synthetase (EC 6.3.4.4)
(IMP--aspartate ligase) (AdSS) (AMPSase)
Length = 428
Score = 402 bits (1034), Expect = e-112
Identities = 210/424 (49%), Positives = 278/424 (65%), Gaps = 6/424 (1%)
Query: 63 VSGVLGCQWGDEGKGKLVDILAQHFQIVARCQGGANAGHTIYNAEGKKFALHLVPSGILN 122
V+ ++G QWGDEGKGK+ D LA+ ++V R QGG NAGHT+ +G ++ LHL+PSGIL
Sbjct: 3 VTVIVGAQWGDEGKGKITDYLAERSEVVVRYQGGNNAGHTV-EKDGVQYKLHLIPSGILY 61
Query: 123 EDTLCVIGNGVVVHLPGLFQEIDNLESNGVSCK-GRILISDRAHLLFDFHQTVDGLREAE 181
D +CVIGNGVVV L +EI++L++ GV K + ISDRAH++F +H D L E
Sbjct: 62 PDKICVIGNGVVVDPSALLKEIEDLKAKGVEVKEDNLKISDRAHVVFPYHIKEDELEEKG 121
Query: 182 LSKSFIGTTKRGIGPCYSSKANRNGIRVGDLRYMETLPQKLDLLLSDAALRFKDFKYGPD 241
+GTTK+GIGPCY K R GIR+ DL E +KL L FKD YG D
Sbjct: 122 KGDEDLGTTKKGIGPCYRDKTERIGIRMCDLMNAEVFREKLKKNLERKNKIFKDI-YGED 180
Query: 242 VLREE--VEKYKRYAERLEPYIADTVHVMNEAITQKKKVLVEGGQATMLDIDFGTYPFVT 299
E E Y+ YAERL PY+ DT ++ + KK+L EG Q T+LD+DFGTYP+VT
Sbjct: 181 GFDFEQIFETYREYAERLRPYVTDTSVLLYNLAKEGKKILFEGAQGTLLDLDFGTYPYVT 240
Query: 300 SSSPSAGGICTGLGIAPRVIGDLVGVVKAYTTRVGSGPFPTEILGPGGDLLRFAGQEFGT 359
+S P AGG G GI P +I +++GVVKAYTTRVG GPFPTE+ GD LR G E+GT
Sbjct: 241 ASHPVAGGATIGAGIGPTMIDNVIGVVKAYTTRVGKGPFPTELKDEIGDFLREKGYEYGT 300
Query: 360 TTGRPRRCGWLDIVALSYSCQINGFSSLNLTKLDVLSDLDEIQLGVSYKHADGTPVQSFP 419
TTGRPRRCGW+DIV L Y+ +++G +SL LTKLD L+ L++I++ YK +G ++ FP
Sbjct: 301 TTGRPRRCGWIDIVMLRYAVRVSGITSLALTKLDTLTGLEKIKICTGYK-INGKIIEDFP 359
Query: 420 SDLRLLEQLKVEYESLPGWKTDISSIRNYSDLPRAAQLYVERIEELVGVPIHYIGVGPGR 479
+ L L+ + YE + GW +I +R++ DLP A+ YV+R+EELVGV I VGP R
Sbjct: 360 ASLEELKMCEPIYEEMEGWSENIQDVRSFEDLPLNAKKYVKRLEELVGVEFSIISVGPER 419
Query: 480 DALI 483
+ I
Sbjct: 420 EETI 423
>PURA_STRAW (Q82ER6) Adenylosuccinate synthetase (EC 6.3.4.4)
(IMP--aspartate ligase) (AdSS) (AMPSase)
Length = 427
Score = 387 bits (995), Expect = e-107
Identities = 209/419 (49%), Positives = 267/419 (62%), Gaps = 4/419 (0%)
Query: 66 VLGCQWGDEGKGKLVDILAQHFQIVARCQGGANAGHTIYNAEGKKFALHLVPSGILNEDT 125
+LG QWGDEGKGK D+L V R QGG NAGHT+ + +K+ALHL+PSGIL +
Sbjct: 6 LLGAQWGDEGKGKATDLLGGSVDYVVRYQGGNNAGHTVVVGD-QKYALHLLPSGILTPEC 64
Query: 126 LCVIGNGVVVHLPGLFQEIDNLESNGVSCKGRILISDRAHLLFDFHQTVDGLREAELSKS 185
VIGNGVVV LF E++ L GV ++LIS AH++ ++ TVD + E L K
Sbjct: 65 TPVIGNGVVVDPSVLFSELNGLNERGVDTS-KLLISGNAHIITPYNVTVDKVTERFLGKR 123
Query: 186 FIGTTKRGIGPCYSSKANRNGIRVGDLRYMETLPQKLDLLLSDA-ALRFKDFKYGPDVLR 244
IGTT RGIGP Y+ K NR GIR+ DL L QK++ L L K F
Sbjct: 124 KIGTTGRGIGPTYADKINRVGIRIQDLYDESILTQKVEAALDGKNQLLTKVFNRRAIEAG 183
Query: 245 EEVEKYKRYAERLEPYIADTVHVMNEAITQKKKVLVEGGQATMLDIDFGTYPFVTSSSPS 304
+ VE+ YA+RL+PY+ADTV V+N+A+ K VL EGGQ T+LDID GTYPFVTSS+P+
Sbjct: 184 QVVEELLTYADRLKPYVADTVLVLNKALDDDKVVLFEGGQGTLLDIDHGTYPFVTSSNPT 243
Query: 305 AGGICTGLGIAPRVIGDLVGVVKAYTTRVGSGPFPTEILGPGGDLLRFAGQEFGTTTGRP 364
AGG CTG G+ P I ++G++KAYTTRVG+GPFPTE+L G+ LR G E G TTGR
Sbjct: 244 AGGACTGSGVGPTKISRVIGILKAYTTRVGAGPFPTELLDEDGEALRRIGGERGVTTGRD 303
Query: 365 RRCGWLDIVALSYSCQINGFSSLNLTKLDVLSDLDEIQLGVSYKHADGTPVQSFPSDLRL 424
RRCGW D V Y+ ++NG + LTKLDVL+ ++I + V+Y+ DG V+ P
Sbjct: 304 RRCGWFDAVIARYATRVNGLTDFFLTKLDVLTGWEQIPVCVAYE-IDGKRVEELPYSQTD 362
Query: 425 LEQLKVEYESLPGWKTDISSIRNYSDLPRAAQLYVERIEELVGVPIHYIGVGPGRDALI 483
K YE+LPGW DI+ + + DLP+ AQ YV +EE+ G PI IGVGPGRD I
Sbjct: 363 FHHAKPIYENLPGWSEDITKAKTFEDLPKNAQAYVRALEEMSGAPISAIGVGPGRDETI 421
>PURA_BIFLO (Q8G6T9) Adenylosuccinate synthetase (EC 6.3.4.4)
(IMP--aspartate ligase) (AdSS) (AMPSase)
Length = 428
Score = 387 bits (994), Expect = e-107
Identities = 204/419 (48%), Positives = 269/419 (63%), Gaps = 4/419 (0%)
Query: 66 VLGCQWGDEGKGKLVDILAQHFQIVARCQGGANAGHTIYNAEGKKFALHLVPSGILNEDT 125
++G QWGDEGKGK D++ VAR GG NAGH++ + + +ALHL+PSGI+N +
Sbjct: 6 LIGAQWGDEGKGKATDLIGTKVDYVARFNGGNNAGHSVVVGD-ESYALHLLPSGIINPNL 64
Query: 126 LCVIGNGVVVHLPGLFQEIDNLESNGVSCKGRILISDRAHLLFDFHQTVDGLREAELSKS 185
VIGNGVVV LF+EID LES G+ C + +S+ AH++ +H+T+D + E L K
Sbjct: 65 TPVIGNGVVVDPEVLFEEIDGLESRGIDCS-HLKVSEAAHIIAPYHRTLDKVTERFLGKH 123
Query: 186 FIGTTKRGIGPCYSSKANRNGIRVGDLRYMETLPQKLDLLLSDA-ALRFKDFKYGPDVLR 244
IGTT RGIGP Y+ K NR GIRV DL + L K++ L + K + P +
Sbjct: 124 KIGTTGRGIGPAYADKINRVGIRVHDLFNADHLHDKVEASLHQKNQMLVKLYNRRPIDVD 183
Query: 245 EEVEKYKRYAERLEPYIADTVHVMNEAITQKKKVLVEGGQATMLDIDFGTYPFVTSSSPS 304
+ E+ + ERL+PY+A+T ++N+A+ + K VL EG QATMLD+D GTYPFVTSS+P+
Sbjct: 184 QTTEELLKLGERLKPYVANTGLILNKALDEGKTVLFEGAQATMLDVDHGTYPFVTSSNPT 243
Query: 305 AGGICTGLGIAPRVIGDLVGVVKAYTTRVGSGPFPTEILGPGGDLLRFAGQEFGTTTGRP 364
AGG CTG G+ P I +VGV KAY TRVG GPFPTE+L G+ LR G EFG TTGRP
Sbjct: 244 AGGACTGTGVGPTRITRVVGVSKAYVTRVGEGPFPTELLDESGEWLRQQGHEFGVTTGRP 303
Query: 365 RRCGWLDIVALSYSCQINGFSSLNLTKLDVLSDLDEIQLGVSYKHADGTPVQSFPSDLRL 424
RRCGW D V Y+ Q+NG + + LTKLDVL+ L EI + V+Y DG P+D
Sbjct: 304 RRCGWFDAVVNRYASQVNGLTDIVLTKLDVLAGLKEIPICVAY-DVDGERHDDMPTDQAA 362
Query: 425 LEQLKVEYESLPGWKTDISSIRNYSDLPRAAQLYVERIEELVGVPIHYIGVGPGRDALI 483
K YE++PGW DIS+ ++ +LP Q YV+R+EEL G I IG GP RD +I
Sbjct: 363 FAAAKPIYETMPGWDEDISNCHSFDELPATCQAYVKRLEELSGCRISAIGTGPQRDHVI 421
>PURA_STRCO (Q9X8P6) Adenylosuccinate synthetase (EC 6.3.4.4)
(IMP--aspartate ligase) (AdSS) (AMPSase)
Length = 427
Score = 384 bits (987), Expect = e-106
Identities = 207/419 (49%), Positives = 267/419 (63%), Gaps = 4/419 (0%)
Query: 66 VLGCQWGDEGKGKLVDILAQHFQIVARCQGGANAGHTIYNAEGKKFALHLVPSGILNEDT 125
+LG QWGDEGKGK D+L V R QGG NAGHT+ + +K+ALHL+PSGIL+
Sbjct: 6 LLGAQWGDEGKGKATDLLGGSVDYVVRYQGGNNAGHTVVVGD-QKYALHLLPSGILSPGC 64
Query: 126 LCVIGNGVVVHLPGLFQEIDNLESNGVSCKGRILISDRAHLLFDFHQTVDGLREAELSKS 185
VIGNGVVV LF E+ L GV ++LIS AH++ ++ TVD + E L K
Sbjct: 65 TPVIGNGVVVDPSVLFSELSGLNERGVDTS-KLLISGNAHIITPYNVTVDKVTERFLGKR 123
Query: 186 FIGTTKRGIGPCYSSKANRNGIRVGDLRYMETLPQKLDLLLS-DAALRFKDFKYGPDVLR 244
IGTT RGIGP Y+ K NR GIRV DL L QK++ L + K +
Sbjct: 124 KIGTTGRGIGPTYADKINRVGIRVQDLYDESILTQKVEAALDVKNQMLTKLYNRRAIATG 183
Query: 245 EEVEKYKRYAERLEPYIADTVHVMNEAITQKKKVLVEGGQATMLDIDFGTYPFVTSSSPS 304
+ VE+ YA++L PY+ADTV V+N+A+ K VL EGGQ T+LDID GTYPFVTSS+P+
Sbjct: 184 QVVEELLGYADKLAPYVADTVLVLNQALDDDKVVLFEGGQGTLLDIDHGTYPFVTSSNPT 243
Query: 305 AGGICTGLGIAPRVIGDLVGVVKAYTTRVGSGPFPTEILGPGGDLLRFAGQEFGTTTGRP 364
AGG CTG G+ P I ++G++KAYTTRVG+GPFPTE+ G+ LR G E G TTGR
Sbjct: 244 AGGACTGAGVGPTKISRVIGILKAYTTRVGAGPFPTELFDEDGEALRRIGGERGVTTGRD 303
Query: 365 RRCGWLDIVALSYSCQINGFSSLNLTKLDVLSDLDEIQLGVSYKHADGTPVQSFPSDLRL 424
RRCGW D V Y+ ++NG + LTKLDVL+ ++I + V+Y+ DG V+ P
Sbjct: 304 RRCGWFDAVIARYATRVNGLTDFFLTKLDVLTGWEQIPVCVAYE-IDGKRVEELPYSQSD 362
Query: 425 LEQLKVEYESLPGWKTDISSIRNYSDLPRAAQLYVERIEELVGVPIHYIGVGPGRDALI 483
K YE+LPGW DI+ +++SDLP+ AQ YV+ +EE+ G PI IGVGPGRD I
Sbjct: 363 FHHAKPVYETLPGWSEDITKAKSFSDLPKNAQAYVKALEEMSGAPISAIGVGPGRDETI 421
>PURA_LACLA (Q9CE93) Adenylosuccinate synthetase (EC 6.3.4.4)
(IMP--aspartate ligase) (AdSS) (AMPSase)
Length = 430
Score = 382 bits (982), Expect = e-106
Identities = 199/416 (47%), Positives = 269/416 (63%), Gaps = 3/416 (0%)
Query: 66 VLGCQWGDEGKGKLVDILAQHFQIVARCQGGANAGHTIYNAEGKKFALHLVPSGILNEDT 125
V+G QWGDEGKGK+ D L+ + +++AR QGG NAGHTI +GKKF LHL+PSGI +
Sbjct: 6 VVGTQWGDEGKGKITDFLSSNAEVIARYQGGDNAGHTIV-IDGKKFKLHLIPSGIFFPEK 64
Query: 126 LCVIGNGVVVHLPGLFQEIDNLESNGVSCKGRILISDRAHLLFDFHQTVDGLREAELSKS 185
+ VIGNGVVV+ L +EI L NGVS + + ISDRAH++ +H+ +D L+E
Sbjct: 65 ISVIGNGVVVNPKSLIEEIAYLAENGVSAES-LRISDRAHVILPYHKKLDFLQEEAKGDK 123
Query: 186 FIGTTKRGIGPCYSSKANRNGIRVGDLRYMETLPQKLDLLLSDAALRF-KDFKYGPDVLR 244
IGTT +GIGP Y KA R GIRV DL E ++L L F K + P
Sbjct: 124 KIGTTIKGIGPAYMDKAARVGIRVADLLDKEIFEERLRTNLEAKNREFVKMYDSEPIEFE 183
Query: 245 EEVEKYKRYAERLEPYIADTVHVMNEAITQKKKVLVEGGQATMLDIDFGTYPFVTSSSPS 304
E E+Y Y ++L+ Y+ DT ++N+A+ K+VL EG Q MLDID GTYPFVTSS+P
Sbjct: 184 EIFEEYYEYGQQLKKYVTDTSVILNDALDAGKRVLFEGAQGVMLDIDQGTYPFVTSSNPV 243
Query: 305 AGGICTGLGIAPRVIGDLVGVVKAYTTRVGSGPFPTEILGPGGDLLRFAGQEFGTTTGRP 364
AGG+ G G+ P I +VGV KAYT+RVG GPFPTE+ G +R G E+GTTTGRP
Sbjct: 244 AGGVTIGSGVGPSKISKVVGVCKAYTSRVGDGPFPTELFDEVGHQIREVGHEYGTTTGRP 303
Query: 365 RRCGWLDIVALSYSCQINGFSSLNLTKLDVLSDLDEIQLGVSYKHADGTPVQSFPSDLRL 424
RR GW D V + ++ +++G ++L+L +DVLS L+ +++ V+Y+ ++G + +P+ L+
Sbjct: 304 RRVGWFDSVVMRHAKRVSGLTNLSLNSIDVLSGLETVKICVAYERSNGEQITHYPASLKE 363
Query: 425 LEQLKVEYESLPGWKTDISSIRNYSDLPRAAQLYVERIEELVGVPIHYIGVGPGRD 480
L K YE LPGW DI+S R +LP AA+ YV R+ ELVGV I VGPGR+
Sbjct: 364 LADCKPIYEELPGWSEDITSCRTLEELPEAARNYVRRVGELVGVRISTFSVGPGRE 419
>PURA_CLOPE (Q8XH63) Adenylosuccinate synthetase (EC 6.3.4.4)
(IMP--aspartate ligase) (AdSS) (AMPSase)
Length = 428
Score = 380 bits (977), Expect = e-105
Identities = 197/420 (46%), Positives = 275/420 (64%), Gaps = 5/420 (1%)
Query: 66 VLGCQWGDEGKGKLVDILAQHFQIVARCQGGANAGHTIYNAEGKKFALHLVPSGILNEDT 125
VLG QWGDEGKGK+ D LA+ ++V R QGG NAGHT+ E K++ LHL+PSGIL+++
Sbjct: 6 VLGAQWGDEGKGKMTDYLAEEAEVVVRFQGGNNAGHTV-EVEDKQYKLHLIPSGILHDEK 64
Query: 126 LCVIGNGVVVHLPGLFQEIDNLESNGVSCKG-RILISDRAHLLFDFHQTVDGLREAELSK 184
L VIGNGVVV LF EID LE GV ++++SDRAHL+ +H T+D L+E K
Sbjct: 65 LNVIGNGVVVDPKALFTEIDYLEGLGVKVTPEKLIVSDRAHLIMPYHITLDKLKEKARGK 124
Query: 185 SFIGTTKRGIGPCYSSKANRNGIRVGDLRYMETLPQKLDLLLSDAALRFKDFKYGPDVLR 244
+ IGTT +GIGPCY+ K R+GIRV DL + ++ +KL + + + + G ++
Sbjct: 125 NDIGTTCKGIGPCYTDKYERSGIRVCDLMHKDSFAEKLRINI-EMKNGYIKLLGGEELNF 183
Query: 245 EEV-EKYKRYAERLEPYIADTVHVMNEAITQKKKVLVEGGQATMLDIDFGTYPFVTSSSP 303
+E+ +Y +AERL PY+ DT + AI K VL EG Q +LDID+GTYP+VTSS+
Sbjct: 184 DEIYNEYMAFAERLRPYVKDTSVEIYNAIQADKNVLFEGAQGMLLDIDYGTYPYVTSSNT 243
Query: 304 SAGGICTGLGIAPRVIGDLVGVVKAYTTRVGSGPFPTEILGPGGDLLRFAGQEFGTTTGR 363
++ G+ +G GI P ++ + VG+ KAYTTRVG GPFPTE+ GD +R G E+G TTGR
Sbjct: 244 TSCGVASGAGIGPNMVTNAVGIAKAYTTRVGKGPFPTELENETGDWIREKGHEYGVTTGR 303
Query: 364 PRRCGWLDIVALSYSCQINGFSSLNLTKLDVLSDLDEIQLGVSYKHADGTPVQSFPSDLR 423
RRCGWLD+V L + ++ G +SL +TK+D L+ LD+IQ+ V Y+ DG + FP+ L
Sbjct: 304 SRRCGWLDLVILKTTTRVCGLTSLVVTKIDTLAGLDKIQMCVGYE-LDGKVIDYFPASLE 362
Query: 424 LLEQLKVEYESLPGWKTDISSIRNYSDLPRAAQLYVERIEELVGVPIHYIGVGPGRDALI 483
L + K YE GW +++ R+Y +LP A+ Y+ RIEE G + +GVGP R+ I
Sbjct: 363 DLARCKPVYEEFEGWGEEVADARSYEELPENAKTYLRRIEEFTGTKVSIVGVGPKRNQTI 422
>PURA_FUSNN (P58793) Adenylosuccinate synthetase (EC 6.3.4.4)
(IMP--aspartate ligase) (AdSS) (AMPSase)
Length = 425
Score = 377 bits (968), Expect = e-104
Identities = 196/416 (47%), Positives = 276/416 (66%), Gaps = 7/416 (1%)
Query: 66 VLGCQWGDEGKGKLVDILAQHFQIVARCQGGANAGHTIYNAEGKKFALHLVPSGILNEDT 125
V+G QWGDEGKGK++D+L++ V R QGG NAGHT+ +G+KF L L+PSG+L T
Sbjct: 6 VVGTQWGDEGKGKIIDVLSEKADYVVRFQGGNNAGHTVV-VDGEKFILQLLPSGVLQAGT 64
Query: 126 LCVIGNGVVVHLPGLFQEIDNLESNGVSCKGRILISDRAHLLFDFHQTVDGLREAELSKS 185
CVIG GVV+ EID +E G ++ISDRAH++ +H +D +RE+ +
Sbjct: 65 -CVIGPGVVIDPKVFLDEIDRIEKRGAKTD-HVIISDRAHVIMPYHIEMDKIRESVEDRI 122
Query: 186 FIGTTKRGIGPCYSSKANRNGIRVGDLRYMETLPQKLDLLLSDAALRFKDFKYGPDVLRE 245
IGTTK+GIGPCY+ K +R+GIR+ DL ++ +KL L + F YG + L
Sbjct: 123 KIGTTKKGIGPCYADKISRDGIRMSDLLDLKQFEEKLRYNLKEKNEIFTKI-YGLEPLDF 181
Query: 246 EV--EKYKRYAERLEPYIADTVHVMNEAITQKKKVLVEGGQATMLDIDFGTYPFVTSSSP 303
+ E+YK YAE+++ I DT+ ++N+A+ + K VL EG QA MLDI++GTYP+VTSSSP
Sbjct: 182 DTIFEEYKGYAEKIKHRIVDTIPMVNKALDENKLVLFEGAQAMMLDINYGTYPYVTSSSP 241
Query: 304 SAGGICTGLGIAPRVIGDLVGVVKAYTTRVGSGPFPTEILGPGGDLLRFAGQEFGTTTGR 363
+ GG+ TG GI+PR I +GV+KAYTTRVG GPF TEI G GD +R G E+G TGR
Sbjct: 242 TLGGVTTGAGISPRKIDKGIGVMKAYTTRVGEGPFVTEIKGEFGDKIRGIGGEYGAVTGR 301
Query: 364 PRRCGWLDIVALSYSCQINGFSSLNLTKLDVLSDLDEIQLGVSYKHADGTPVQSFPSDLR 423
PRRCGWLD+V Y+ +ING + + +TK+DVLS L ++++ +Y+ DG + P+D +
Sbjct: 302 PRRCGWLDLVVGRYATEINGLTDIVMTKIDVLSGLGKLKICTAYE-IDGVIHEYVPADTK 360
Query: 424 LLEQLKVEYESLPGWKTDISSIRNYSDLPRAAQLYVERIEELVGVPIHYIGVGPGR 479
L++ YE L GW DI+ I+ Y DLP + Y+ER++E++G PI + VGP R
Sbjct: 361 SLDRAIPIYEELDGWDEDITQIKKYEDLPVNCRKYLERVQEILGCPISVVSVGPDR 416
>PURA_CHLTE (Q8KAK6) Adenylosuccinate synthetase (EC 6.3.4.4)
(IMP--aspartate ligase) (AdSS) (AMPSase)
Length = 435
Score = 376 bits (966), Expect = e-104
Identities = 198/422 (46%), Positives = 274/422 (64%), Gaps = 4/422 (0%)
Query: 66 VLGCQWGDEGKGKLVDILAQHFQIVARCQGGANAGHTIYNAEGKKFALHLVPSGILNEDT 125
++G Q+GDEGKGKLVD L+ + IV R QGGANAGHTI +GK LHL+PSGI N+D
Sbjct: 16 LVGTQFGDEGKGKLVDYLSDKYDIVVRYQGGANAGHTIC-FDGKTVVLHLIPSGIFNKDC 74
Query: 126 LCVIGNGVVVHLPGLFQEIDNLESNGVSCKGRILISDRAHLLFDFHQTVDGLREAELS-K 184
+CVIGNGVV+ L EI +E G KGR+ IS AHL+ +H+ +D L E+ LS
Sbjct: 75 ICVIGNGVVIDPNALMDEIKKVEELGYDVKGRLYISHNAHLIMPYHKRLDSLSESCLSGD 134
Query: 185 SFIGTTKRGIGPCYSSKANRNGIRVGDLRYMETLPQKL-DLLLSDAALRFKDFKYGPDVL 243
+ IGTT RGIGP Y K R GIRV DL + L +KL + L + L K ++ +
Sbjct: 135 NKIGTTGRGIGPSYEDKFARKGIRVVDLLDRDVLKEKLRENLAAKNKLISKVYEQEEIDV 194
Query: 244 REEVEKYKRYAERLEPYIADTVHVMNEAITQKKKVLVEGGQATMLDIDFGTYPFVTSSSP 303
+ +Y+ + + ++PY+ +T +N I K +L+EG Q +LD+D GTYPFVTSS+P
Sbjct: 195 EAIIREYEEFDKAIDPYVTNTQLFLNRQIKAGKTILLEGAQGCLLDVDHGTYPFVTSSNP 254
Query: 304 SAGGICTGLGIAPRVIGDLVGVVKAYTTRVGSGPFPTEILGPGGDLLRFAGQEFGTTTGR 363
++GG CTG G+AP +G ++GV KAYTTRVG+G FPTE+ G+ L G EFG TTGR
Sbjct: 255 TSGGACTGSGVAPNHVGKIIGVCKAYTTRVGNGDFPTELDDETGEALGRIGCEFGATTGR 314
Query: 364 PRRCGWLDIVALSYSCQINGFSSLNLTKLDVLSDLDEIQLGVSYKHADGTPVQSFPSDLR 423
RRCGWLD+VAL YS ++G + L LTKLDVL +EI++ SY DG + FP++ +
Sbjct: 315 KRRCGWLDLVALRYSVTVSGVTELALTKLDVLDTFEEIKVCTSYM-LDGKEIFDFPTEHQ 373
Query: 424 LLEQLKVEYESLPGWKTDISSIRNYSDLPRAAQLYVERIEELVGVPIHYIGVGPGRDALI 483
L +++ Y+SL GW + ++++++ AQ YV +EE + VP+ +I VGPGRD +
Sbjct: 374 TLSRVQPVYKSLKGWMASNAKAKSFAEMHPNAQAYVNFLEEALEVPVTFISVGPGRDETV 433
Query: 484 FK 485
FK
Sbjct: 434 FK 435
>PURA_STRR6 (P65888) Adenylosuccinate synthetase (EC 6.3.4.4)
(IMP--aspartate ligase) (AdSS) (AMPSase)
Length = 428
Score = 375 bits (964), Expect = e-103
Identities = 192/416 (46%), Positives = 272/416 (65%), Gaps = 4/416 (0%)
Query: 66 VLGCQWGDEGKGKLVDILAQHFQIVARCQGGANAGHTIYNAEGKKFALHLVPSGILNEDT 125
V+G QWGDEGKGK+ D L+ + +++AR QGG NAGHTI +GKKF LHL+PSGI +
Sbjct: 6 VVGTQWGDEGKGKITDFLSANAEVIARYQGGDNAGHTIV-IDGKKFKLHLIPSGIFFPEK 64
Query: 126 LCVIGNGVVVHLPGLFQEIDNLESNGVSCKGRILISDRAHLLFDFHQTVDGLREAELSKS 185
+ VIGNG+VV+ L +E+ L GV+ + ISDRAH++ +H +D L+E +
Sbjct: 65 ISVIGNGMVVNPKSLVKELSYLHEEGVTTDN-LRISDRAHVILPYHIELDRLQEEAKGDN 123
Query: 186 FIGTTKRGIGPCYSSKANRNGIRVGDLRYMETLPQKLDLLLSDAALRFKDFKYGPDVLRE 245
IGTT +GIGP Y KA R GIR+ DL + ++L+ L++ F+ ++ +
Sbjct: 124 KIGTTIKGIGPAYMDKAARVGIRIADLLDKDIFRERLERNLAEKNRLFEKLYDSKAIVFD 183
Query: 246 EV-EKYKRYAERLEPYIADTVHVMNEAITQKKKVLVEGGQATMLDIDFGTYPFVTSSSPS 304
++ E+Y Y ++++ Y+ DT ++N+A+ K+VL EG Q MLDID GTYPFVTSS+P
Sbjct: 184 DIFEEYYEYGQQIKKYVIDTSVILNDALDNGKRVLFEGAQGVMLDIDQGTYPFVTSSNPV 243
Query: 305 AGGICTGLGIAPRVIGDLVGVVKAYTTRVGSGPFPTEILGPGGDLLRFAGQEFGTTTGRP 364
AGG+ G G+ P I +VGV KAYT+RVG GPFPTE+ G+ +R G E+GTTTGRP
Sbjct: 244 AGGVTIGSGVGPSKIDKVVGVCKAYTSRVGDGPFPTELFDEVGERIREVGHEYGTTTGRP 303
Query: 365 RRCGWLDIVALSYSCQINGFSSLNLTKLDVLSDLDEIQLGVSYKHADGTPVQSFPSDLRL 424
RR GW D V + +S +++G ++L+L +DVLS LD +++ V+Y DG + +P+ L
Sbjct: 304 RRVGWFDSVVMRHSRRVSGITNLSLNSIDVLSGLDTVKICVAY-DLDGQRIDYYPASLEQ 362
Query: 425 LEQLKVEYESLPGWKTDISSIRNYSDLPRAAQLYVERIEELVGVPIHYIGVGPGRD 480
L++ K YE LPGW DI+ +RN DLP A+ YV R+ ELVGV I VGPGR+
Sbjct: 363 LKRCKPIYEELPGWSEDITGVRNLEDLPENARNYVRRVSELVGVRISTFSVGPGRE 418
Database: sprot
Posted date: Nov 25, 2004 10:54 AM
Number of letters in database: 59,974,054
Number of sequences in database: 164,201
Lambda K H
0.320 0.140 0.416
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 60,724,160
Number of Sequences: 164201
Number of extensions: 2769579
Number of successful extensions: 6908
Number of sequences better than 10.0: 147
Number of HSP's better than 10.0 without gapping: 136
Number of HSP's successfully gapped in prelim test: 11
Number of HSP's that attempted gapping in prelim test: 6257
Number of HSP's gapped (non-prelim): 161
length of query: 485
length of database: 59,974,054
effective HSP length: 114
effective length of query: 371
effective length of database: 41,255,140
effective search space: 15305656940
effective search space used: 15305656940
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 68 (30.8 bits)
Medicago: description of AC143341.5