BLASTP 2.2.2 [Dec-14-2001]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= AC143339.7 - phase: 0 
         (358 letters)

Database: sprot 
           164,201 sequences; 59,974,054 total letters

Searching..................................................done

                                                                   Score     E
Sequences producing significant alignments:                        (bits)  Value

P2C3_SCHPO (Q09173) Protein phosphatase 2C homolog 3 (EC 3.1.3.1...   250  4e-66
P2C2_SCHPO (Q09172) Protein phosphatase 2C homolog 2 (EC 3.1.3.1...   243  4e-64
P2C_PARTE (P49444) Protein phosphatase 2C (EC 3.1.3.16) (PP2C)        231  3e-60
P2C2_CAEEL (P49596) Probable protein phosphatase 2C T23F11.1 (EC...   226  7e-59
P2CB_MOUSE (P36993) Protein phosphatase 2C beta isoform (EC 3.1....   211  2e-54
P2CB_RAT (P35815) Protein phosphatase 2C beta isoform (EC 3.1.3....   207  3e-53
P2CA_RAT (P20650) Protein phosphatase 2C alpha isoform (EC 3.1.3...   205  1e-52
P2CA_MOUSE (P49443) Protein phosphatase 2C alpha isoform (EC 3.1...   205  1e-52
P2CA_BOVIN (O62829) Protein phosphatase 2C alpha isoform (EC 3.1...   205  2e-52
P2CA_HUMAN (P35813) Protein phosphatase 2C alpha isoform (EC 3.1...   204  2e-52
P2CB_HUMAN (O75688) Protein phosphatase 2C beta isoform (EC 3.1....   204  3e-52
P2CB_BOVIN (O62830) Protein phosphatase 2C beta isoform (EC 3.1....   204  4e-52
P2CA_RABIT (P35814) Protein phosphatase 2C alpha isoform (EC 3.1...   203  5e-52
P2C2_YEAST (P39966) Protein phosphatase 2C homolog 2 (EC 3.1.3.1...   203  6e-52
P2C3_YEAST (P34221) Protein phosphatase 2C homolog 3 (EC 3.1.3.1...   199  9e-51
P2C1_CAEEL (P49595) Probable protein phosphatase 2C F42G9.1 (EC ...   185  2e-46
P2CG_BOVIN (P79126) Protein phosphatase 2C gamma isoform (EC 3.1...   182  1e-45
P2CG_HUMAN (O15355) Protein phosphatase 2C gamma isoform (EC 3.1...   179  1e-44
P2CG_MOUSE (Q61074) Protein phosphatase 2C gamma isoform (EC 3.1...   177  4e-44
P2C3_ARATH (P49599) Protein phosphatase 2C PPH1 (EC 3.1.3.16) (P...   134  3e-31

>P2C3_SCHPO (Q09173) Protein phosphatase 2C homolog 3 (EC 3.1.3.16)
           (PP2C-3)
          Length = 414

 Score =  250 bits (638), Expect = 4e-66
 Identities = 147/343 (42%), Positives = 196/343 (56%), Gaps = 53/343 (15%)

Query: 1   MGTTLSIPKTEKFSEDGENDNLRYGLSSMQGWRATMEDAHAAHLDVDSST-----SFFGV 55
           MG TLS P TEK S +G N+ + YGLSSMQGWR +MEDAH+A L ++ S       FF V
Sbjct: 1   MGQTLSEPVTEKHSVNGSNEFVLYGLSSMQGWRISMEDAHSAILSMECSAVKDPVDFFAV 60

Query: 56  YDGHGGKAVAKFCAKHLHQQVLKSEEYIAGDVGTSLTKAFLRMDEMMRGQRGWRELAVLG 115
           YDGHGG  VAK+C  +L Q + K+ ++  GD   +L  +FL  D+           A+L 
Sbjct: 61  YDGHGGDKVAKWCGSNLPQILEKNPDFQKGDFVNALKSSFLNADK-----------AIL- 108

Query: 116 DKVKGFNGIIEGLIRSPRSNDNKDQSDDWAFEKGPHSDFDGPNSGSTACVAIIRNNLLFV 175
                                     DD  F   P        SG TA V +   N L+ 
Sbjct: 109 --------------------------DDDQFHTDP--------SGCTATVVLRVGNKLYC 134

Query: 176 ANAGDSRCVISRNGQAYNLSRDHKPELVIEKERIYKAGGFIHAGRINGSLNLARAIGDVD 235
           ANAGDSR V+   G A  LS DHKP    EK RI  AGGF+  GR+NG+L L+RAIGD +
Sbjct: 135 ANAGDSRTVLGSKGIAKPLSADHKPSNEAEKARICAAGGFVDFGRVNGNLALSRAIGDFE 194

Query: 236 FKNNRFLSAEKQVVTANPDINIVDLHDEDEFIVIACDGIWDCLSSQQLVDFVRQELLLET 295
           FKN+  L  EKQ+VTA PD+ + ++ D+DEF+V+ACDGIWDC +SQQ+++FVR+ ++  T
Sbjct: 195 FKNSN-LEPEKQIVTALPDVVVHEITDDDEFVVLACDGIWDCKTSQQVIEFVRRGIVAGT 253

Query: 296 KLSEVCERVLDRCLAPSL-AVGDGCDNMTMILVQFKKPLQTSA 337
            L ++ E ++D C+A      G GCDNMT+ +V   +    SA
Sbjct: 254 SLEKIAENLMDNCIASDTETTGLGCDNMTVCIVALLQENDKSA 296


>P2C2_SCHPO (Q09172) Protein phosphatase 2C homolog 2 (EC 3.1.3.16)
           (PP2C-2)
          Length = 370

 Score =  243 bits (621), Expect = 4e-64
 Identities = 140/337 (41%), Positives = 187/337 (54%), Gaps = 54/337 (16%)

Query: 1   MGTTLSIPKTEKFSEDGENDNLRYGLSSMQGWRATMEDAHAAHLDVDSS------TSFFG 54
           MG TLS P  +K S  G +  L +G+S MQGWR +MEDAH A L+   S      TSFFG
Sbjct: 1   MGQTLSEPVLDKHSSSGGDRWLHFGVSHMQGWRISMEDAHCALLNFTDSNSSNPPTSFFG 60

Query: 55  VYDGHGGKAVAKFCAKHLHQQVLKSEEYIAGDVGTSLTKAFLRMDEMMRGQRGWRELAVL 114
           V+DGHGG  VAK+C +HL   +     +  G+   +L   FL  D  +   R  +E    
Sbjct: 61  VFDGHGGDRVAKYCRQHLPDIIKSQPSFWKGNYDEALKSGFLAADNALMQDRDMQE---- 116

Query: 115 GDKVKGFNGIIEGLIRSPRSNDNKDQSDDWAFEKGPHSDFDGPNSGSTACVA-IIRNNLL 173
                                                       SG TA  A I+ + ++
Sbjct: 117 ------------------------------------------DPSGCTATTALIVDHQVI 134

Query: 174 FVANAGDSRCVISRNGQAYNLSRDHKPELVIEKERIYKAGGFIHAGRINGSLNLARAIGD 233
           + ANAGDSR V+ R G A  LS DHKP   +EK RI  AGGFI  GR+NGSL L+RAIGD
Sbjct: 135 YCANAGDSRTVLGRKGTAEPLSFDHKPNNDVEKARITAAGGFIDFGRVNGSLALSRAIGD 194

Query: 234 VDFKNNRFLSAEKQVVTANPDINIVDLHDEDEFIVIACDGIWDCLSSQQLVDFVRQELLL 293
            ++K +  L  EKQ+VTA PD+ I ++  +DEF+++ACDGIWDC SSQQ+V+FVR+ ++ 
Sbjct: 195 FEYKKDSSLPPEKQIVTAFPDVVIHNIDPDDEFLILACDGIWDCKSSQQVVEFVRRGIVA 254

Query: 294 ETKLSEVCERVLDRCLAP-SLAVGDGCDNMTMILVQF 329
              L  +CE ++DRC+A  S + G GCDNMT+ +V F
Sbjct: 255 RQSLEVICENLMDRCIASNSESCGIGCDNMTICIVAF 291


>P2C_PARTE (P49444) Protein phosphatase 2C (EC 3.1.3.16) (PP2C)
          Length = 300

 Score =  231 bits (588), Expect = 3e-60
 Identities = 129/335 (38%), Positives = 192/335 (56%), Gaps = 39/335 (11%)

Query: 1   MGTTLSIPKTEKFSEDGENDNLRYGLSSMQGWRATMEDAHAAHLDVDSSTSFFGVYDGHG 60
           MG  LS PK +K +  G+  ++ +  S MQGWR TMEDAH    D+    S FGV+DGHG
Sbjct: 1   MGPYLSQPKRDKTTTTGQGKSVIFAASEMQGWRNTMEDAHIHRHDIIQDVSVFGVFDGHG 60

Query: 61  GKAVAKFCAKHLHQQVLKSEEYIAGDVGTSLTKAFLRMDEMMRGQRGWRELAVLGDKVKG 120
           G+ VA+F  KH   ++LK++ +       +L + FL+MDE++    G +EL         
Sbjct: 61  GREVAQFVEKHFVDELLKNKNFKEQKFEEALKETFLKMDELLLTPEGQKEL--------- 111

Query: 121 FNGIIEGLIRSPRSNDNKDQSDDWAFEKGPHSDFDGPNSGSTACVAIIRNNLLFVANAGD 180
                         N  K             +D D   +G TA VA+I  N L+VANAGD
Sbjct: 112 --------------NQYKA------------TDTDESYAGCTANVALIYKNTLYVANAGD 145

Query: 181 SRCVISRNGQAYNLSRDHKPELVIEKERIYKAGGFIHAGRINGSLNLARAIGDVDFKNNR 240
           SR V+ RN   +++S DHKP+   EK RI +AGGF+  GR+NG+LNL+RA+GD+++K + 
Sbjct: 146 SRSVLCRNNTNHDMSVDHKPDNPEEKSRIERAGGFVSDGRVNGNLNLSRALGDLEYKRDN 205

Query: 241 FLSAEKQVVTANPDINIVDLHDEDEFIVIACDGIWDCLSSQQLVDFVR----QELLLETK 296
            L + +Q++ A PD+   +L  +D+FI++ CDG+++ L+ Q+L+  V     Q  + E  
Sbjct: 206 KLRSNEQLIIALPDVKKTELTPQDKFILMGCDGVFETLNHQELLKQVNSTIGQAQVTEEL 265

Query: 297 LSEVCERVLDRCLAPSLAVGDGCDNMTMILVQFKK 331
           L +  E +LD+ LAP  + G GCDNMT ILV  ++
Sbjct: 266 LKKAAEDLLDQLLAPDTSQGTGCDNMTTILVYLRR 300


>P2C2_CAEEL (P49596) Probable protein phosphatase 2C T23F11.1 (EC
           3.1.3.16) (PP2C)
          Length = 356

 Score =  226 bits (576), Expect = 7e-59
 Identities = 132/330 (40%), Positives = 184/330 (55%), Gaps = 49/330 (14%)

Query: 1   MGTTLSIPKTEKFSEDGENDNLRYGLSSMQGWRATMEDAHAAHLDV--DSSTSFFGVYDG 58
           MG TLS P T+K S    N+N   G S MQGWR  MEDAH   L +  D   +FF VYDG
Sbjct: 1   MGQTLSEPVTKKESASCANENYLVGSSCMQGWRVDMEDAHTHLLSLPDDPKCAFFAVYDG 60

Query: 59  HGGKAVAKFCAKHLHQQVLKSEEYIAGDVGTSLTKAFLRMDEMMRGQRGWRELAVLGDKV 118
           HGG  V+++   +LH++V+  +E+  G++  ++ K FL +D+ MR               
Sbjct: 61  HGGSKVSQYSGINLHKKVVAQKEFSEGNMKEAIEKGFLELDQQMRV-------------- 106

Query: 119 KGFNGIIEGLIRSPRSNDNKDQSDDWAFEKGPHSDFDGPNSGSTACVAIIRNNLLFVANA 178
                             +++  DD               SG+TA V +I+   ++  NA
Sbjct: 107 ------------------DEETKDDV--------------SGTTAVVVLIKEGDVYCGNA 134

Query: 179 GDSRCVISRNGQAYNLSRDHKPELVIEKERIYKAGGFIHAGRINGSLNLARAIGDVDFKN 238
           GDSR V S  G+A  LS DHKP    E  RI  AGG++   R+NG+L L+RA+GD  FKN
Sbjct: 135 GDSRAVSSVVGEARPLSFDHKPSHETEARRIIAAGGWVEFNRVNGNLALSRALGDFAFKN 194

Query: 239 NRFLSAEKQVVTANPDINIVDLHDEDEFIVIACDGIWDCLSSQQLVDFVRQELLLETKLS 298
                AE+Q+VTA PD+    L  + EFIV+ACDGIWD +++Q++VDFVR++L  +    
Sbjct: 195 CDTKPAEEQIVTAFPDVITDKLTPDHEFIVLACDGIWDVMTNQEVVDFVREKLAEKRDPQ 254

Query: 299 EVCERVLDRCLAPSLAVGD-GCDNMTMILV 327
            +CE +L RCLAP   +G  GCDNMT++LV
Sbjct: 255 SICEELLTRCLAPDCQMGGLGCDNMTVVLV 284


>P2CB_MOUSE (P36993) Protein phosphatase 2C beta isoform (EC
           3.1.3.16) (PP2C-beta) (IA) (Protein phosphatase 1B)
          Length = 390

 Score =  211 bits (538), Expect = 2e-54
 Identities = 129/359 (35%), Positives = 184/359 (50%), Gaps = 64/359 (17%)

Query: 1   MGTTLSIPKTEKFSEDGENDNLRYGLSSMQGWRATMEDAHAAHLDVD---SSTSFFGVYD 57
           MG  L  PKTEK +  G  + LRYGLSSMQGWR  MEDAH A + +     + SFF VYD
Sbjct: 1   MGAFLDKPKTEKHNAHGAGNGLRYGLSSMQGWRVEMEDAHTAVVGIPHGLDNWSFFAVYD 60

Query: 58  GHGGKAVAKFCAKHLHQQVLKSEEYIAGD------------VGTSLTKAFLRMDEMMRGQ 105
           GH G  VA +C+ HL + +  +E++ A D            V T +   FL++DE MR  
Sbjct: 61  GHAGSRVANYCSTHLLEHITTNEDFRAADKSGSALEPSVESVKTGIRTGFLKIDEYMRN- 119

Query: 106 RGWRELAVLGDKVKGFNGIIEGLIRSPRSNDNKDQSDDWAFEKGPHSDFDGPNSGSTACV 165
                          F+ +  G+ RS                            GSTA  
Sbjct: 120 ---------------FSDLRNGMDRS----------------------------GSTAVG 136

Query: 166 AIIRNNLLFVANAGDSRCVISRNGQAYNLSRDHKPELVIEKERIYKAGGFIHAGRINGSL 225
            ++    ++  N GDSR V+ RNGQ    ++DHKP   +EKERI  AGG +   R+NGSL
Sbjct: 137 VMVSPTHMYFINCGDSRAVLCRNGQVCFSTQDHKPCNPVEKERIQNAGGSVMIQRVNGSL 196

Query: 226 NLARAIGDVDFKNNRFLSAEKQVVTANPDINIVDLHDEDEFIVIACDGIWDCLSSQQLVD 285
            ++RA+GD D+K        +Q+V+  P++  +   +EDEF+V+ACDGIWD +S+++L +
Sbjct: 197 AVSRALGDYDYKCVDGKGPTEQLVSPEPEVYEIVRAEEDEFVVLACDGIWDVMSNEELCE 256

Query: 286 FVRQELLLETKLSEVCERVLDRCLAPSLAVGDGCDNMTMILVQFKKPLQTSAPAQEQSS 344
           FV+  L +   L  VC  V+D CL          DNM+++LV F    + S  A ++ S
Sbjct: 257 FVKSRLEVSDDLENVCNWVVDTCLHKG-----SRDNMSVVLVCFSNAPKVSEEAVKRDS 310


>P2CB_RAT (P35815) Protein phosphatase 2C beta isoform (EC 3.1.3.16)
           (PP2C-beta) (IA) (Protein phosphatase 1B)
          Length = 390

 Score =  207 bits (527), Expect = 3e-53
 Identities = 129/354 (36%), Positives = 179/354 (50%), Gaps = 64/354 (18%)

Query: 1   MGTTLSIPKTEKFSEDGENDNLRYGLSSMQGWRATMEDAHAAHLDVDSST---SFFGVYD 57
           MG  L  PKTEK +  G  + LRYGLSSMQGWR  MEDAH A + +       SFF VYD
Sbjct: 1   MGAFLDKPKTEKHNAHGAGNGLRYGLSSMQGWRVEMEDAHTAVVGIPHGLEDWSFFAVYD 60

Query: 58  GHGGKAVAKFCAKHLHQQVLKSEEYIAGD------------VGTSLTKAFLRMDEMMRGQ 105
           GH G  VA +C+ HL + +  +E++ A D            V T +   FL++DE MR  
Sbjct: 61  GHAGSRVANYCSTHLLEHITTNEDFRAADKSGFALEPSVENVKTGIRTGFLKIDEYMRN- 119

Query: 106 RGWRELAVLGDKVKGFNGIIEGLIRSPRSNDNKDQSDDWAFEKGPHSDFDGPNSGSTACV 165
                          F+ +  G+ RS                            GSTA  
Sbjct: 120 ---------------FSDLRNGMDRS----------------------------GSTAVG 136

Query: 166 AIIRNNLLFVANAGDSRCVISRNGQAYNLSRDHKPELVIEKERIYKAGGFIHAGRINGSL 225
            +I    ++  N GDSR V+ RNGQ    ++DHKP   +EKERI  AGG +   R+NGSL
Sbjct: 137 VMISPTHIYFINCGDSRAVLCRNGQVCFSTQDHKPCNPMEKERIQNAGGSVMIQRVNGSL 196

Query: 226 NLARAIGDVDFKNNRFLSAEKQVVTANPDINIVDLHDEDEFIVIACDGIWDCLSSQQLVD 285
            ++RA+GD D+K        +Q+V+  P++  +   +EDEF+V+ACDGIWD +S+++L +
Sbjct: 197 AVSRALGDYDYKCVDGKGPTEQLVSPEPEVYEILRAEEDEFVVLACDGIWDVMSNEELCE 256

Query: 286 FVRQELLLETKLSEVCERVLDRCLAPSLAVGDGCDNMTMILVQFKKPLQTSAPA 339
           FV   L +   L  VC  V+D CL          DNM+++LV F    + S  A
Sbjct: 257 FVNSRLEVSDDLENVCNWVVDTCLHKG-----SRDNMSIVLVCFANAPKVSDEA 305


>P2CA_RAT (P20650) Protein phosphatase 2C alpha isoform (EC
           3.1.3.16) (PP2C-alpha) (IA) (Protein phosphatase 1A)
          Length = 382

 Score =  205 bits (522), Expect = 1e-52
 Identities = 124/355 (34%), Positives = 183/355 (50%), Gaps = 60/355 (16%)

Query: 1   MGTTLSIPKTEKFSEDGENDNLRYGLSSMQGWRATMEDAHAAHLDVDSST---SFFGVYD 57
           MG  L  PK EK +  G+ + LRYGLSSMQGWR  MEDAH A + + S     SFF VYD
Sbjct: 1   MGAFLDKPKMEKHNAQGQGNGLRYGLSSMQGWRVEMEDAHTAVIGLPSGLETWSFFAVYD 60

Query: 58  GHGGKAVAKFCAKHLHQQVLKSEEYIAG-------DVGTSLTKAFLRMDEMMRGQRGWRE 110
           GH G  VAK+C +HL   +  ++++          +V   +   FL +DE MR       
Sbjct: 61  GHAGSQVAKYCCEHLLDHITNNQDFKGSAGAPSVENVKNGIRTGFLEIDEHMR------- 113

Query: 111 LAVLGDKVKGFNGIIEGLIRSPRSNDNKDQSDDWAFEKGPHSDFDGPNSGSTACVAIIRN 170
             V+ +K  G +                                    SGSTA   +I  
Sbjct: 114 --VMSEKKHGAD-----------------------------------RSGSTAVGVLISP 136

Query: 171 NLLFVANAGDSRCVISRNGQAYNLSRDHKPELVIEKERIYKAGGFIHAGRINGSLNLARA 230
              +  N GDSR ++ RN + +  ++DHKP   +EKERI  AGG +   R+NGSL ++RA
Sbjct: 137 QHTYFINCGDSRGLLCRNRKVHFFTQDHKPSNPLEKERIQNAGGSVMIQRVNGSLAVSRA 196

Query: 231 IGDVDFKNNRFLSAEKQVVTANPDINIVDLHDE-DEFIVIACDGIWDCLSSQQLVDFVRQ 289
           +GD D+K        +Q+V+  P+++ ++  +E D+FI++ACDGIWD + +++L DFVR 
Sbjct: 197 LGDFDYKCVHGKGPTEQLVSPEPEVHDIERSEEDDQFIILACDGIWDVMGNEELCDFVRS 256

Query: 290 ELLLETKLSEVCERVLDRCLAPSLAVGDGCDNMTMILVQFKKPLQTSAPAQEQSS 344
            L +   L +VC  V+D CL          DNM++IL+ F    + SA A ++ +
Sbjct: 257 RLEVTDDLEKVCNEVVDTCLYKG-----SRDNMSVILICFPNAPKVSAEAVKKEA 306


>P2CA_MOUSE (P49443) Protein phosphatase 2C alpha isoform (EC
           3.1.3.16) (PP2C-alpha) (IA) (Protein phosphatase 1A)
          Length = 382

 Score =  205 bits (522), Expect = 1e-52
 Identities = 124/355 (34%), Positives = 183/355 (50%), Gaps = 60/355 (16%)

Query: 1   MGTTLSIPKTEKFSEDGENDNLRYGLSSMQGWRATMEDAHAAHLDVDSST---SFFGVYD 57
           MG  L  PK EK +  G+ + LRYGLSSMQGWR  MEDAH A + + S     SFF VYD
Sbjct: 1   MGAFLDKPKMEKHNAQGQGNGLRYGLSSMQGWRVEMEDAHTAVIGLPSGLETWSFFAVYD 60

Query: 58  GHGGKAVAKFCAKHLHQQVLKSEEYIAG-------DVGTSLTKAFLRMDEMMRGQRGWRE 110
           GH G  VAK+C +HL   +  ++++          +V   +   FL +DE MR       
Sbjct: 61  GHAGSQVAKYCCEHLLDHITNNQDFRGSAGAPSVENVKNGIRTGFLEIDEHMR------- 113

Query: 111 LAVLGDKVKGFNGIIEGLIRSPRSNDNKDQSDDWAFEKGPHSDFDGPNSGSTACVAIIRN 170
             V+ +K  G +                                    SGSTA   +I  
Sbjct: 114 --VMSEKKHGAD-----------------------------------RSGSTAVGVLISP 136

Query: 171 NLLFVANAGDSRCVISRNGQAYNLSRDHKPELVIEKERIYKAGGFIHAGRINGSLNLARA 230
              +  N GDSR ++ RN + +  ++DHKP   +EKERI  AGG +   R+NGSL ++RA
Sbjct: 137 QHTYFINCGDSRGLLCRNRKVHFFTQDHKPSNPLEKERIQNAGGSVMIQRVNGSLAVSRA 196

Query: 231 IGDVDFKNNRFLSAEKQVVTANPDINIVDLHDE-DEFIVIACDGIWDCLSSQQLVDFVRQ 289
           +GD D+K        +Q+V+  P+++ ++  +E D+FI++ACDGIWD + +++L DFVR 
Sbjct: 197 LGDFDYKCVHGKGPTEQLVSPEPEVHDIERSEEDDQFIILACDGIWDVMGNEELCDFVRS 256

Query: 290 ELLLETKLSEVCERVLDRCLAPSLAVGDGCDNMTMILVQFKKPLQTSAPAQEQSS 344
            L +   L +VC  V+D CL          DNM++IL+ F    + SA A ++ +
Sbjct: 257 RLEVTDDLEKVCNEVVDTCLYKG-----SRDNMSVILICFPSAPKVSAEAVKKEA 306


>P2CA_BOVIN (O62829) Protein phosphatase 2C alpha isoform (EC
           3.1.3.16) (PP2C-alpha)
          Length = 382

 Score =  205 bits (521), Expect = 2e-52
 Identities = 124/350 (35%), Positives = 179/350 (50%), Gaps = 60/350 (17%)

Query: 1   MGTTLSIPKTEKFSEDGENDNLRYGLSSMQGWRATMEDAHAAHLDVDSST---SFFGVYD 57
           MG  L  PK EK +  G+ + LRYGLSSMQGWR  MEDAH A + + S     SFF VYD
Sbjct: 1   MGAFLDKPKMEKHNAQGQGNGLRYGLSSMQGWRVEMEDAHTAVIGLPSGLETWSFFAVYD 60

Query: 58  GHGGKAVAKFCAKHLHQQVLKSEEYIAG-------DVGTSLTKAFLRMDEMMRGQRGWRE 110
           GH G  VAK+C +HL   +  ++++          +V   +   FL +DE MR       
Sbjct: 61  GHAGSQVAKYCCEHLLDHITNNQDFKGSAGAPSVENVKNGIRTGFLEIDEHMR------- 113

Query: 111 LAVLGDKVKGFNGIIEGLIRSPRSNDNKDQSDDWAFEKGPHSDFDGPNSGSTACVAIIRN 170
             V+ +K  G +                                    SGSTA   +I  
Sbjct: 114 --VMSEKKHGAD-----------------------------------RSGSTAVGVLISP 136

Query: 171 NLLFVANAGDSRCVISRNGQAYNLSRDHKPELVIEKERIYKAGGFIHAGRINGSLNLARA 230
              +  N GDSR ++ RN + Y  ++DHKP   +EKERI  AGG +   R+NGSL ++RA
Sbjct: 137 QHTYFINCGDSRGLLCRNRKVYFFTQDHKPSNPLEKERIQNAGGSVMIQRVNGSLAVSRA 196

Query: 231 IGDVDFKNNRFLSAEKQVVTANPDINIVDLHDE-DEFIVIACDGIWDCLSSQQLVDFVRQ 289
           +GD D+K        +Q+V+  P+++ ++  +E D+FI++ACDGIWD + +++L DFVR 
Sbjct: 197 LGDFDYKCVHGKGPTEQLVSPEPEVHDIERSEEDDQFIILACDGIWDVMGNEELCDFVRS 256

Query: 290 ELLLETKLSEVCERVLDRCLAPSLAVGDGCDNMTMILVQFKKPLQTSAPA 339
            L +   L +VC  V+D CL          DNM++IL+ F    + S  A
Sbjct: 257 RLEVTDDLEKVCNEVVDTCLYKG-----SRDNMSVILICFPNAPKVSPEA 301


>P2CA_HUMAN (P35813) Protein phosphatase 2C alpha isoform (EC
           3.1.3.16) (PP2C-alpha) (IA) (Protein phosphatase 1A)
          Length = 382

 Score =  204 bits (520), Expect = 2e-52
 Identities = 124/355 (34%), Positives = 183/355 (50%), Gaps = 60/355 (16%)

Query: 1   MGTTLSIPKTEKFSEDGENDNLRYGLSSMQGWRATMEDAHAAHLDVDS---STSFFGVYD 57
           MG  L  PK EK +  G+ + LRYGLSSMQGWR  MEDAH A + + S   S SFF VYD
Sbjct: 1   MGAFLDKPKMEKHNAQGQGNGLRYGLSSMQGWRVEMEDAHTAVIGLPSGLESWSFFAVYD 60

Query: 58  GHGGKAVAKFCAKHLHQQVLKSEEYIAG-------DVGTSLTKAFLRMDEMMRGQRGWRE 110
           GH G  VAK+C +HL   +  ++++          +V   +   FL +DE MR       
Sbjct: 61  GHAGSQVAKYCCEHLLDHITNNQDFKGSAGAPSVENVKNGIRTGFLEIDEHMR------- 113

Query: 111 LAVLGDKVKGFNGIIEGLIRSPRSNDNKDQSDDWAFEKGPHSDFDGPNSGSTACVAIIRN 170
             V+ +K  G +                                    SGSTA   +I  
Sbjct: 114 --VMSEKKHGAD-----------------------------------RSGSTAVGVLISP 136

Query: 171 NLLFVANAGDSRCVISRNGQAYNLSRDHKPELVIEKERIYKAGGFIHAGRINGSLNLARA 230
              +  N GDSR ++ RN + +  ++DHKP   +EKERI  AGG +   R+NGSL ++RA
Sbjct: 137 QHTYFINCGDSRGLLCRNRKVHFFTQDHKPSNPLEKERIQNAGGSVMIQRVNGSLAVSRA 196

Query: 231 IGDVDFKNNRFLSAEKQVVTANPDINIVDLHDE-DEFIVIACDGIWDCLSSQQLVDFVRQ 289
           +GD D+K        +Q+V+  P+++ ++  +E D+FI++ACDGIWD + +++L DFVR 
Sbjct: 197 LGDFDYKCVHGKGPTEQLVSPEPEVHDIERSEEDDQFIILACDGIWDVMGNEELCDFVRS 256

Query: 290 ELLLETKLSEVCERVLDRCLAPSLAVGDGCDNMTMILVQFKKPLQTSAPAQEQSS 344
            L +   L +VC  V+D CL          DNM++IL+ F    + S  A ++ +
Sbjct: 257 RLEVTDDLEKVCNEVVDTCLYKG-----SRDNMSVILICFPNAPKVSPEAVKKEA 306


>P2CB_HUMAN (O75688) Protein phosphatase 2C beta isoform (EC
           3.1.3.16) (PP2C-beta)
          Length = 479

 Score =  204 bits (519), Expect = 3e-52
 Identities = 126/348 (36%), Positives = 185/348 (52%), Gaps = 42/348 (12%)

Query: 1   MGTTLSIPKTEKFSEDGENDNLRYGLSSMQGWRATMEDAHAAHLDVDSST---SFFGVYD 57
           MG  L  PKTEK +  G  + LRYGLSSMQGWR  MEDAH A + +       SFF VYD
Sbjct: 1   MGAFLDKPKTEKHNAHGAGNGLRYGLSSMQGWRVEMEDAHTAVVGIPHGLEDWSFFAVYD 60

Query: 58  GHGGKAVAKFCAKHLHQQVLKSEEY-IAGDVGTSLTKAFLRMDEMMRGQRGWRELAVLGD 116
           GH G  VA +C+ HL + +  +E++  AG  G++L    L ++ +  G R       + +
Sbjct: 61  GHAGSRVANYCSTHLLEHITTNEDFRAAGKSGSALE---LSVENVKNGIR--TGFLKIDE 115

Query: 117 KVKGFNGIIEGLIRSPRSNDNKDQSDDWAFEKGPHSDFDGPNSGSTACVAIIRNNLLFVA 176
            ++ F+ +  G+ RS                            GSTA   +I    ++  
Sbjct: 116 YMRNFSDLRNGMDRS----------------------------GSTAVGVMISPKHIYFI 147

Query: 177 NAGDSRCVISRNGQAYNLSRDHKPELVIEKERIYKAGGFIHAGRINGSLNLARAIGDVDF 236
           N GDSR V+ RNGQ    ++DHKP    EKERI  AGG +   R+NGSL ++RA+GD D+
Sbjct: 148 NCGDSRAVLYRNGQVCFSTQDHKPCNPREKERIQNAGGSVMIQRVNGSLAVSRALGDYDY 207

Query: 237 KNNRFLSAEKQVVTANPDINIVDLHDEDEFIVIACDGIWDCLSSQQLVDFVRQELLLETK 296
           K        +Q+V+  P++  +   +EDEFI++ACDGIWD +S+++L ++V+  L +   
Sbjct: 208 KCVDGKGPTEQLVSPEPEVYEILRAEEDEFIILACDGIWDVMSNEELCEYVKSRLEVSDD 267

Query: 297 LSEVCERVLDRCLAPSLAVGDGCDNMTMILVQFKKPLQTSAPAQEQSS 344
           L  VC  V+D CL          DNM+++LV F    + S  A ++ S
Sbjct: 268 LENVCNWVVDTCLHKG-----SRDNMSIVLVCFSNAPKVSDEAVKKDS 310


>P2CB_BOVIN (O62830) Protein phosphatase 2C beta isoform (EC
           3.1.3.16) (PP2C-beta)
          Length = 387

 Score =  204 bits (518), Expect = 4e-52
 Identities = 129/359 (35%), Positives = 183/359 (50%), Gaps = 64/359 (17%)

Query: 1   MGTTLSIPKTEKFSEDGENDNLRYGLSSMQGWRATMEDAHAAHLDVDSST---SFFGVYD 57
           MG  L  PKTEK +  G  + LRYGLSSMQGWR  MEDAH A + +       SFF VYD
Sbjct: 1   MGAFLDKPKTEKHNAHGAGNGLRYGLSSMQGWRVEMEDAHTAVVGIPHGLEDWSFFAVYD 60

Query: 58  GHGGKAVAKFCAKHLHQQVLKSEEY-IAGDVGTSLTKA-----------FLRMDEMMRGQ 105
           GH G  VA +C+ HL + +  +E++  AG  G++L  +           FL++DE MR  
Sbjct: 61  GHAGSRVANYCSTHLLEHITNNEDFRAAGKSGSALEPSVENVKNGIRTGFLKIDEYMRN- 119

Query: 106 RGWRELAVLGDKVKGFNGIIEGLIRSPRSNDNKDQSDDWAFEKGPHSDFDGPNSGSTACV 165
                          F+ +  G+ RS                            GSTA  
Sbjct: 120 ---------------FSDLRNGMDRS----------------------------GSTAVG 136

Query: 166 AIIRNNLLFVANAGDSRCVISRNGQAYNLSRDHKPELVIEKERIYKAGGFIHAGRINGSL 225
            +I    ++  N GDSR V+ R+GQ    ++DHKP    EKERI  AGG +   R+NGSL
Sbjct: 137 VMISPKHIYFINCGDSRAVLYRSGQVCFSTQDHKPCNPREKERIQNAGGSVMIQRVNGSL 196

Query: 226 NLARAIGDVDFKNNRFLSAEKQVVTANPDINIVDLHDEDEFIVIACDGIWDCLSSQQLVD 285
            ++RA+GD D+K        +Q+V+  P++  +   +EDEFI++ACDGIWD +S+++L +
Sbjct: 197 AVSRALGDYDYKCVDGKGPTEQLVSPEPEVYEILRAEEDEFIILACDGIWDVMSNEELCE 256

Query: 286 FVRQELLLETKLSEVCERVLDRCLAPSLAVGDGCDNMTMILVQFKKPLQTSAPAQEQSS 344
           FV+  L +   L  VC  V+D CL          DNM+++LV F    + S  A  + S
Sbjct: 257 FVKSRLEVSDDLENVCNWVVDTCLHKG-----SRDNMSIVLVCFSNAPKVSDEAMRKDS 310


>P2CA_RABIT (P35814) Protein phosphatase 2C alpha isoform (EC
           3.1.3.16) (PP2C-alpha) (IA) (Protein phosphatase 1A)
          Length = 382

 Score =  203 bits (517), Expect = 5e-52
 Identities = 123/355 (34%), Positives = 182/355 (50%), Gaps = 60/355 (16%)

Query: 1   MGTTLSIPKTEKFSEDGENDNLRYGLSSMQGWRATMEDAHAAHLDVDSST---SFFGVYD 57
           MG  L  PK EK +  G+ + LRYGLSSMQGWR  MEDAH A + + S     SFF VYD
Sbjct: 1   MGAFLDKPKMEKHNAQGQGNGLRYGLSSMQGWRVEMEDAHTAVIGLPSGLETWSFFAVYD 60

Query: 58  GHGGKAVAKFCAKHLHQQVLKSEEYIAG-------DVGTSLTKAFLRMDEMMRGQRGWRE 110
           GH G  VAK+C +HL   +  ++++          +V   +   FL +DE MR       
Sbjct: 61  GHAGSQVAKYCCEHLLDHITNNQDFKGSAGAPSVENVKNGIRTGFLEIDEHMR------- 113

Query: 111 LAVLGDKVKGFNGIIEGLIRSPRSNDNKDQSDDWAFEKGPHSDFDGPNSGSTACVAIIRN 170
             V+ +K  G +                                    SGSTA   +I  
Sbjct: 114 --VMSEKKHGAD-----------------------------------RSGSTAVGVLISP 136

Query: 171 NLLFVANAGDSRCVISRNGQAYNLSRDHKPELVIEKERIYKAGGFIHAGRINGSLNLARA 230
              +  N GDSR ++ RN + +  ++DHKP   +EKERI  AGG +   R+NGSL ++RA
Sbjct: 137 QHTYFINCGDSRGLLCRNRKVHFFTQDHKPSNPLEKERIQNAGGSVMIQRVNGSLAVSRA 196

Query: 231 IGDVDFKNNRFLSAEKQVVTANPDINIVDLHDE-DEFIVIACDGIWDCLSSQQLVDFVRQ 289
           +GD D+K        +Q+V+  P+++ ++  +E D+FI++ACDGIWD + +++L DFVR 
Sbjct: 197 LGDFDYKCVHGKGPTEQLVSPEPEVHDIERSEEDDQFIILACDGIWDVMGNEELCDFVRS 256

Query: 290 ELLLETKLSEVCERVLDRCLAPSLAVGDGCDNMTMILVQFKKPLQTSAPAQEQSS 344
            L +   L +VC  V+D CL          DNM++IL+ F    + S  A ++ +
Sbjct: 257 RLEVTDDLEKVCNEVVDTCLYKG-----SRDNMSVILICFPNAPKVSPEAVKKEA 306


>P2C2_YEAST (P39966) Protein phosphatase 2C homolog 2 (EC 3.1.3.16)
           (PP2C-2)
          Length = 464

 Score =  203 bits (516), Expect = 6e-52
 Identities = 127/360 (35%), Positives = 187/360 (51%), Gaps = 55/360 (15%)

Query: 1   MGTTLSIPKTEKFSEDGENDNLRYGLSSMQGWRATMEDAHAAHLDVDSST-----SFFGV 55
           MG  LS P  +K S  G +    +GL +MQGWR +MED+H    +V + +     +F+G+
Sbjct: 1   MGQILSNPVIDKESHSGADSLTAFGLCAMQGWRMSMEDSHILEPNVLTKSDKDHIAFYGI 60

Query: 56  YDGHGGKAVAKFCAKHLHQQVLKSEEYIAGDVGTSLTKAFLRMDEMMRGQRGWRELAVLG 115
           +DGHGG  VA++C   + + + + + +  G++  +L   F+  D                
Sbjct: 61  FDGHGGAKVAEYCGNKIVEILQEQKSFHEGNLPRALIDTFINTD---------------- 104

Query: 116 DKVKGFNGIIEGLIRSPRSNDNKDQSDDWAFEKGPHSDFDGPNSGSTACVAIIRN--NLL 173
             VK        L++ P   ++                    +SG TA   ++    NLL
Sbjct: 105 --VK--------LLQDPVMKED--------------------HSGCTATSILVSKSQNLL 134

Query: 174 FVANAGDSRCVISRNGQAYNLSRDHKPELVIEKERIYKAGGFIHAGRINGSLNLARAIGD 233
              NAGDSR V++ +G A  LS DHKP L  EK RI  A GF+   R+NG+L L+RAIGD
Sbjct: 135 VCGNAGDSRTVLATDGNAKALSYDHKPTLASEKSRIVAADGFVEMDRVNGNLALSRAIGD 194

Query: 234 VDFKNNRFLSAEKQVVTANPDINIVDL-HDEDEFIVIACDGIWDCLSSQQLVDFVRQELL 292
            +FK+N  L  E+Q+VT  PDI    L +D DEF+++ACDGIWDCL+SQ  VD V   L 
Sbjct: 195 FEFKSNPKLGPEEQIVTCVPDILEHSLDYDRDEFVILACDGIWDCLTSQDCVDLVHLGLR 254

Query: 293 LETKLSEVCERVLDRCLAPSL-AVGDGCDNMTMILVQFKKPLQTSAPAQEQSSSNEQDAS 351
               L+E+  R++D C AP+    G GCDNM++++V   K  +  A   ++  S     S
Sbjct: 255 EGKTLNEISSRIIDVCCAPTTEGTGIGCDNMSIVVVALLKEGEDVAQWSDRMKSKAHRTS 314


>P2C3_YEAST (P34221) Protein phosphatase 2C homolog 3 (EC 3.1.3.16)
           (PP2C-3)
          Length = 468

 Score =  199 bits (506), Expect = 9e-51
 Identities = 127/356 (35%), Positives = 186/356 (51%), Gaps = 58/356 (16%)

Query: 1   MGTTLSIPKTEKFSEDGENDNLRYGLSSMQGWRATMEDAHAAHLDV-----DSSTSFFGV 55
           MG  LS P  +K    G +    +GL +MQGWR +MEDAH    ++     +   +F+G+
Sbjct: 1   MGQILSNPIIDKEHHSGTDCLTAFGLCAMQGWRMSMEDAHIVEPNLLAESDEEHLAFYGI 60

Query: 56  YDGHGGKAVAKFCAKHLHQQVLKSEEYIAGDVGTSLTKAFLRMD-EMMRGQRGWRELAVL 114
           +DGHGG +VA+FC   +   + K E + +G +   L   FL  D E+++           
Sbjct: 61  FDGHGGSSVAEFCGSKMISILKKQESFKSGMLEQCLIDTFLATDVELLK----------- 109

Query: 115 GDKVKGFNGIIEGLIRSPRSNDNKDQSDDWAFEKGPHSDFDGPNSGSTACVAIIRN--NL 172
                                D K + D               +SG TA V ++     L
Sbjct: 110 ---------------------DEKLKDD---------------HSGCTATVILVSQLKKL 133

Query: 173 LFVANAGDSRCVISRNGQAYNLSRDHKPELVIEKERIYKAGGFIHAGRINGSLNLARAIG 232
           L  AN+GDSR V+S  G +  +S DHKP L+ EK RI  A GF+   R+NG+L L+RAIG
Sbjct: 134 LICANSGDSRTVLSTGGNSKAMSFDHKPTLLSEKSRIVAADGFVEMDRVNGNLALSRAIG 193

Query: 233 DVDFKNNRFLSAEKQVVTANPDINIVDL-HDEDEFIVIACDGIWDCLSSQQLVDFVRQEL 291
           D +FK+N  L   +QVVT  PDI   +L +DEDEF+++ACDGIWDCL+SQ+ VD V   +
Sbjct: 194 DFEFKSNTKLGPHEQVVTCVPDIICHNLNYDEDEFVILACDGIWDCLTSQECVDLVHYGI 253

Query: 292 LL-ETKLSEVCERVLDRCLAPSL-AVGDGCDNMTMILVQFKKPLQTSAPAQEQSSS 345
                 LS++  R++D C +P+    G GCDNM++ +V   K  ++ +   E+  S
Sbjct: 254 SQGNMTLSDISSRIVDVCCSPTTEGSGIGCDNMSISIVALLKENESESQWFERMRS 309


>P2C1_CAEEL (P49595) Probable protein phosphatase 2C F42G9.1 (EC
           3.1.3.16) (PP2C)
          Length = 491

 Score =  185 bits (469), Expect = 2e-46
 Identities = 93/181 (51%), Positives = 125/181 (68%), Gaps = 1/181 (0%)

Query: 152 SDFDGPNSGSTACVAIIRNNLLFVANAGDSRCVISRNGQAYNLSRDHKPELVIEKERIYK 211
           ++  G +SG+TACV ++  + + VANAGDSR V+ RNG+A +LS DHKPE  +E  RI+ 
Sbjct: 308 AEVPGEDSGTTACVCLVGKDKVIVANAGDSRAVLCRNGKAVDLSVDHKPEDEVETNRIHA 367

Query: 212 AGGFIHAGRINGSLNLARAIGDVDFKNNRFLSAEKQVVTANPDINIVDLHDEDEFIVIAC 271
           AGG I  GR+NG LNL+RA GD  +K N+ L  ++Q++TA PD+ I  L  EDEFIV+AC
Sbjct: 368 AGGQIEDGRVNGGLNLSRAFGDHAYKKNQELGLKEQMITALPDVKIEALTPEDEFIVVAC 427

Query: 272 DGIWDCLSSQQLVDFVRQELLLETKLSEVCERVLDRCLAPSL-AVGDGCDNMTMILVQFK 330
           DGIW+ + SQQ+VDFVR  L   +  +EVC+ + D CLA S    G GCDNMT+I   F 
Sbjct: 428 DGIWNSMESQQVVDFVRDLLAKGSSCAEVCDALCDACLADSTDGDGTGCDNMTVICTTFD 487

Query: 331 K 331
           +
Sbjct: 488 R 488



 Score = 93.2 bits (230), Expect = 9e-19
 Identities = 47/119 (39%), Positives = 68/119 (56%)

Query: 1   MGTTLSIPKTEKFSEDGENDNLRYGLSSMQGWRATMEDAHAAHLDVDSSTSFFGVYDGHG 60
           MG  L+ P  EK  E+G  + L Y  ++MQGWR   EDAH   +D+ +    FGVYDGHG
Sbjct: 1   MGAYLNKPIIEKEKEEGSGNGLSYACTTMQGWRVNQEDAHNCVVDLHTDWHMFGVYDGHG 60

Query: 61  GKAVAKFCAKHLHQQVLKSEEYIAGDVGTSLTKAFLRMDEMMRGQRGWRELAVLGDKVK 119
           G  V+KF +  L   + + + + A DV   L KAF+  D+ +R +   +EL  +GD+ K
Sbjct: 61  GTEVSKFTSAKLPDFLKERKFWEADDVAECLQKAFVDFDDFIRAEESMKELKDIGDEGK 119


>P2CG_BOVIN (P79126) Protein phosphatase 2C gamma isoform (EC
           3.1.3.16) (PP2C-gamma) (Protein phosphatase
           magnesium-dependent 1 gamma) (Protein phosphatase 1B)
           (Magnesium-dependent calcium inhibitable phosphatase)
           (MCPP)
          Length = 543

 Score =  182 bits (461), Expect = 1e-45
 Identities = 97/194 (50%), Positives = 135/194 (69%), Gaps = 9/194 (4%)

Query: 156 GPNSGSTACVAIIRNNLLFVANAGDSRCVISRNGQAYNLSRDHKPELVIEKERIYKAGGF 215
           G +SG+TA VA+IR   L VANAGDSRCV+S  G+A ++S DHKPE  +E  RI  AGG 
Sbjct: 322 GSDSGTTAVVALIRGKQLIVANAGDSRCVVSEAGKALDMSYDHKPEDEVELARIKNAGGK 381

Query: 216 IHA-GRINGSLNLARAIGDVDFKNNRFLSAEKQVVTANPDINIVDLHDEDEFIVIACDGI 274
           +   GR+NG LNL+RAIGD  +K N+ L  E+Q+++A PDI ++ L D+ EF+VIACDGI
Sbjct: 382 VTMDGRVNGGLNLSRAIGDHFYKRNKNLPPEEQMISALPDIKVLTLTDDHEFMVIACDGI 441

Query: 275 WDCLSSQQLVDFVRQELLLETK------LSEVCERVLDRCLAPSLA-VGDGCDNMTMILV 327
           W+ +SSQ+++DF++ ++    +      LS + E +LD+CLAP  +  G GCDNMT I++
Sbjct: 442 WNVMSSQEVIDFIQSKISQRDENGELRLLSSIVEYLLDQCLAPDTSGDGTGCDNMTCIII 501

Query: 328 QFKKPLQTSAPAQE 341
            F KP  T+AP  E
Sbjct: 502 CF-KPRNTAAPQPE 514



 Score = 94.0 bits (232), Expect = 5e-19
 Identities = 51/120 (42%), Positives = 70/120 (57%), Gaps = 3/120 (2%)

Query: 1   MGTTLSIPKTEKFSEDGENDN---LRYGLSSMQGWRATMEDAHAAHLDVDSSTSFFGVYD 57
           MG  LS P T K S DG   +   L YG S+MQGWR +MEDAH    ++DS T+ F VYD
Sbjct: 1   MGAYLSQPNTVKCSGDGVGASRLPLPYGFSAMQGWRVSMEDAHNCIQELDSETAMFSVYD 60

Query: 58  GHGGKAVAKFCAKHLHQQVLKSEEYIAGDVGTSLTKAFLRMDEMMRGQRGWRELAVLGDK 117
           GHGG+ VA +CAK+L   +   + Y  G +  +L  AFL +D  +  +   +ELA +  +
Sbjct: 61  GHGGEEVALYCAKYLPDIIKDQKAYKEGKLQKALEDAFLAIDAKLTTEEVIKELAQIAGR 120


>P2CG_HUMAN (O15355) Protein phosphatase 2C gamma isoform (EC
           3.1.3.16) (PP2C-gamma) (Protein phosphatase
           magnesium-dependent 1 gamma) (Protein phosphatase 1C)
          Length = 546

 Score =  179 bits (454), Expect = 1e-44
 Identities = 97/220 (44%), Positives = 144/220 (65%), Gaps = 10/220 (4%)

Query: 136 DNKDQSDDWAFEKGPHSDFDGPNSGSTACVAIIRNNLLFVANAGDSRCVISRNGQAYNLS 195
           D++++ ++         +  G +SG+TA VA+IR   L VANAGDSRCV+S  G+A ++S
Sbjct: 304 DDEEEEEEMMVPGMEGKEEPGSDSGTTAVVALIRGKQLIVANAGDSRCVVSEAGKALDMS 363

Query: 196 RDHKPELVIEKERIYKAGGFIHA-GRINGSLNLARAIGDVDFKNNRFLSAEKQVVTANPD 254
            DHKPE  +E  RI  AGG +   GR+NG LNL+RAIGD  +K N+ L  E+Q+++A PD
Sbjct: 364 YDHKPEDEVELARIKNAGGKVTMDGRVNGGLNLSRAIGDHFYKRNKNLPPEEQMISALPD 423

Query: 255 INIVDLHDEDEFIVIACDGIWDCLSSQQLVDFVRQELLLETK------LSEVCERVLDRC 308
           I ++ L D+ EF+VIACDGIW+ +SSQ++VDF++ ++    +      LS + E +LD+C
Sbjct: 424 IKVLTLTDDHEFMVIACDGIWNVMSSQEVVDFIQSKISQRDENGELRLLSSIVEELLDQC 483

Query: 309 LAPSLA-VGDGCDNMTMILVQFKKPLQTSAPAQEQSSSNE 347
           LAP  +  G GCDNMT I++ FK   + +A  Q +S   +
Sbjct: 484 LAPDTSGDGTGCDNMTCIIICFKP--RNTAELQPESGKRK 521



 Score = 92.4 bits (228), Expect = 2e-18
 Identities = 51/120 (42%), Positives = 69/120 (57%), Gaps = 3/120 (2%)

Query: 1   MGTTLSIPKTEKFSEDGENDN---LRYGLSSMQGWRATMEDAHAAHLDVDSSTSFFGVYD 57
           MG  LS P T K S DG       L YG S+MQGWR +MEDAH    ++DS T+ F VYD
Sbjct: 1   MGAYLSQPNTVKCSGDGVGAPRLPLPYGFSAMQGWRVSMEDAHNCIPELDSETAMFSVYD 60

Query: 58  GHGGKAVAKFCAKHLHQQVLKSEEYIAGDVGTSLTKAFLRMDEMMRGQRGWRELAVLGDK 117
           GHGG+ VA +CAK+L   +   + Y  G +  +L  AFL +D  +  +   +ELA +  +
Sbjct: 61  GHGGEEVALYCAKYLPDIIKDQKAYKEGKLQKALEDAFLAIDAKLTTEEVIKELAQIAGR 120


>P2CG_MOUSE (Q61074) Protein phosphatase 2C gamma isoform (EC
           3.1.3.16) (PP2C-gamma) (Protein phosphatase
           magnesium-dependent 1 gamma) (Protein phosphatase 1C)
           (Fibroblast growth factor inducible protein 13) (FIN13)
          Length = 542

 Score =  177 bits (449), Expect = 4e-44
 Identities = 96/211 (45%), Positives = 137/211 (64%), Gaps = 8/211 (3%)

Query: 156 GPNSGSTACVAIIRNNLLFVANAGDSRCVISRNGQAYNLSRDHKPELVIEKERIYKAGGF 215
           G +SG+TA VA+IR   L VANAGDSRCV+S  G+A ++S DHKPE  +E  RI  AGG 
Sbjct: 321 GSDSGTTAVVALIRGKQLIVANAGDSRCVVSEAGKALDMSYDHKPEDEVELARIKNAGGK 380

Query: 216 IHA-GRINGSLNLARAIGDVDFKNNRFLSAEKQVVTANPDINIVDLHDEDEFIVIACDGI 274
           +   GR+NG LNL+RAIGD  +K N+ L  ++Q+++A PDI ++ L D+ EF+VIACDGI
Sbjct: 381 VTMDGRVNGGLNLSRAIGDHFYKRNKNLPPQEQMISALPDIKVLTLTDDHEFMVIACDGI 440

Query: 275 WDCLSSQQLVDFVRQELLLETK------LSEVCERVLDRCLAPSLA-VGDGCDNMTMILV 327
           W+ +SSQ++VDF++ ++    +      LS + E +LD+CLAP  +  G GCDNMT I++
Sbjct: 441 WNVMSSQEVVDFIQSKISQRDENGELRLLSSIVEELLDQCLAPDTSGDGTGCDNMTCIII 500

Query: 328 QFKKPLQTSAPAQEQSSSNEQDASEPTLENS 358
            FK        A+      E+  S    E++
Sbjct: 501 CFKPRNTVELQAESGKRKLEEALSTEGAEDT 531



 Score = 91.3 bits (225), Expect = 3e-18
 Identities = 50/120 (41%), Positives = 69/120 (56%), Gaps = 3/120 (2%)

Query: 1   MGTTLSIPKTEKFSEDGENDN---LRYGLSSMQGWRATMEDAHAAHLDVDSSTSFFGVYD 57
           MG  LS P T K S DG       L YG S+MQGWR +MEDAH    ++D+ T+ F VYD
Sbjct: 1   MGAYLSQPNTVKCSGDGVGAPRLPLPYGFSAMQGWRVSMEDAHNCIPELDNETAMFSVYD 60

Query: 58  GHGGKAVAKFCAKHLHQQVLKSEEYIAGDVGTSLTKAFLRMDEMMRGQRGWRELAVLGDK 117
           GHGG+ VA +CAK+L   +   + Y  G +  +L  AFL +D  +  +   +ELA +  +
Sbjct: 61  GHGGEEVALYCAKYLPDIIKDQKAYKEGKLQKALQDAFLAIDAKLTTEEVIKELAQIAGR 120


>P2C3_ARATH (P49599) Protein phosphatase 2C PPH1 (EC 3.1.3.16)
           (PP2C)
          Length = 388

 Score =  134 bits (338), Expect = 3e-31
 Identities = 106/346 (30%), Positives = 163/346 (46%), Gaps = 65/346 (18%)

Query: 22  LRYGLSSMQGWRATMEDAHAAHLDVDSSTSFFGVYDGHGGKAVAKFCAKHLHQQVLKSEE 81
           +R+G +S+QG+R  MED      D   S S+  V+DGH G +  KF  + L+++ + +  
Sbjct: 58  IRWGYTSVQGFRDEMEDDIVIRSDAVDSFSYAAVFDGHAGSSSVKFLREELYKECVGA-- 115

Query: 82  YIAGDVGTSLTKAFLRMDEMMRGQRGWRELAVLGDKVKGFNGIIEGLIRSPRSNDNKDQS 141
                         L+   ++ G          GD    F  I E LI++  S D     
Sbjct: 116 --------------LQAGSLLNG----------GD----FAAIKEALIKAFESVDRNLLK 147

Query: 142 DDWAFEKGPHSDFDGPNSGSTACVAIIRNNLLFVANAGDSRCVISRNGQAYNLSRDHKP- 200
             W    G   D     SGSTA V IIRN++ F+A+ GDS  V+SR+GQ   L+  H+P 
Sbjct: 148 --WLEANGDEED----ESGSTATVMIIRNDVSFIAHIGDSCAVLSRSGQIEELTDYHRPY 201

Query: 201 ----ELVIEKERIYKAGGFIHAGRINGSLNLARAIGDVDFK----------------NNR 240
                 + E +R+ +AGG+I  GRI G + ++RA GD+ FK                + +
Sbjct: 202 GSSRAAIQEVKRVKEAGGWIVNGRICGDIAVSRAFGDIRFKTKKNDMLKKGVDEGRWSEK 261

Query: 241 FLSA---EKQVVTANPDINIVDLHDEDEFIVIACDGIWDCLSSQQLVDFVRQELLLETKL 297
           F+S    +  +V A PDI  V L  + EFI++A DG+WD + S  +V +VR +L     +
Sbjct: 262 FVSRIEFKGDMVVATPDIFQVPLTSDVEFIILASDGLWDYMKSSDVVSYVRDQLRKHGNV 321

Query: 298 SEVCERVLDRCLAPSLAVGDGCDNMTMILVQFKKPLQTSAPAQEQS 343
              CE      LA         DN+++I+    +    + PAQ Q+
Sbjct: 322 QLACE-----SLAQVALDRRSQDNISIIIADLGRTEWKNLPAQRQN 362


  Database: sprot
    Posted date:  Nov 25, 2004 10:54 AM
  Number of letters in database: 59,974,054
  Number of sequences in database:  164,201
  
Lambda     K      H
   0.317    0.134    0.393 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 43,072,709
Number of Sequences: 164201
Number of extensions: 1833209
Number of successful extensions: 4343
Number of sequences better than 10.0: 61
Number of HSP's better than 10.0 without gapping: 46
Number of HSP's successfully gapped in prelim test: 15
Number of HSP's that attempted gapping in prelim test: 4161
Number of HSP's gapped (non-prelim): 105
length of query: 358
length of database: 59,974,054
effective HSP length: 111
effective length of query: 247
effective length of database: 41,747,743
effective search space: 10311692521
effective search space used: 10311692521
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 66 (30.0 bits)