BLASTP 2.2.2 [Dec-14-2001]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= AC142498.7 + phase: 0 
         (1705 letters)

Database: sprot 
           164,201 sequences; 59,974,054 total letters

Searching..................................................done

                                                                   Score     E
Sequences producing significant alignments:                        (bits)  Value

CLH1_HUMAN (Q00610) Clathrin heavy chain 1 (CLH-17)                  1891  0.0
CLH_BOVIN (P49951) Clathrin heavy chain                              1889  0.0
CLH_RAT (P11442) Clathrin heavy chain                                1887  0.0
CLH_DROME (P29742) Clathrin heavy chain                              1881  0.0
CLH2_HUMAN (P53675) Clathrin heavy chain 2 (CLH-22)                  1825  0.0
CLH_DICDI (P25870) Clathrin heavy chain                              1809  0.0
CLH_CAEEL (P34574) Probable clathrin heavy chain                     1801  0.0
CLH_SCHPO (Q10161) Probable clathrin heavy chain                     1618  0.0
CLH_YEAST (P22137) Clathrin heavy chain                              1453  0.0
DIA2_HUMAN (O60879) Diaphanous protein homolog 2 (Diaphanous-rel...    49  9e-05
DIA2_MOUSE (O70566) Diaphanous protein homolog 2 (Diaphanous-rel...    49  2e-04
DIA_DROME (P48608) Diaphanous protein                                  46  8e-04
PRA_MYCTU (O53426) Proline-rich antigen homolog                        46  0.001
DIA3_HUMAN (Q9NSV4) Diaphanous protein homolog 3 (Diaphanous-rel...    45  0.002
SEPA_EMENI (P78621) Cytokinesis protein sepA (FH1/2 protein) (Fo...    44  0.003
DIA1_HUMAN (O60610) Diaphanous protein homolog 1 (Diaphanous-rel...    44  0.004
SF01_HUMAN (Q15637) Splicing factor 1 (Zinc finger protein 162) ...    43  0.007
DIA1_MOUSE (O08808) Diaphanous protein homolog 1 (Diaphanous-rel...    43  0.007
FMN2_MOUSE (Q9JL04) Formin 2                                           42  0.011
SMR1_MOUSE (Q61900) Submaxillary gland androgen regulated protei...    41  0.025

>CLH1_HUMAN (Q00610) Clathrin heavy chain 1 (CLH-17)
          Length = 1674

 Score = 1891 bits (4899), Expect = 0.0
 Identities = 949/1700 (55%), Positives = 1255/1700 (73%), Gaps = 36/1700 (2%)

Query: 8    PILMREALTLPSIGINPQHITFTHVTMESDKYICVRE-TAPQNSVVIVDMNMPNQPLRRP 66
            PI  +E L L ++GINP +I F+ +TMESDK+IC+RE    Q  VVI+DMN P+ P+RRP
Sbjct: 5    PIRFQEHLQLQNLGINPANIGFSTLTMESDKFICIREKVGEQAQVVIIDMNDPSNPIRRP 64

Query: 67   ITADSALMNPNSRILALKAQLQGTTQDHLQIFNIELKAKMKSYQMPEQVVFWKWISPKLL 126
            I+ADSA+MNP S+++ALKA   G T   LQIFNIE+K+KMK++ M + V FWKWIS   +
Sbjct: 65   ISADSAIMNPASKVIALKA---GKT---LQIFNIEMKSKMKAHTMTDDVTFWKWISLNTV 118

Query: 127  GLVTQTSVYHWSIEGDSEPVKMFERTANLANNQIINYRCDPTEKWLVLIGIAPGSPERPQ 186
             LVT  +VYHWS+EG+S+PVKMF+R ++LA  QIINYR D  +KWL+L GI+     +  
Sbjct: 119  ALVTDNAVYHWSMEGESQPVKMFDRHSSLAGCQIINYRTDAKQKWLLLTGISA----QQN 174

Query: 187  LVKGNMQLFSVEQQRSQALEAHAASFAQFKVPGNENPSTLISFATKTVNAGQVISKLHVI 246
             V G MQL+SV+++ SQ +E HAASFAQFK+ GN   STL  FA +    GQ   KLH+I
Sbjct: 175  RVVGAMQLYSVDRKVSQPIEGHAASFAQFKMEGNAEESTLFCFAVR----GQAGGKLHII 230

Query: 247  ELGAQP-GKPSFTKKQADLFFPPDFADDFPVSMQISHKYSLIYVITKLGLLFVYDLETAT 305
            E+G  P G   F KK  D+FFPP+  +DFPV+MQIS K+ ++++ITK G + +YDLET T
Sbjct: 231  EVGTPPTGNQPFPKKAVDVFFPPEAQNDFPVAMQISEKHDVVFLITKYGYIHLYDLETGT 290

Query: 306  AVYRNRISPDPIFLTSEATSVGGFYAINRRGQVLLATVNEQTIVNFVSGQLNNLELAVNL 365
             +Y NRIS + IF+T+   +  G   +NR+GQVL   V E+ I+ +++  L N +LA+ +
Sbjct: 291  CIYMNRISGETIFVTAPHEATAGIIGVNRKGQVLSVCVEEENIIPYITNVLQNPDLALRM 350

Query: 366  AKRGNLPGAEKLVVERFHELFAQTKYKEAAELAAESPQGILRTPDTVAKFQSVPVQAGQT 425
            A R NL GAE+L   +F+ LFAQ  Y EAA++AA +P+GILRTPDT+ +FQSVP Q GQT
Sbjct: 351  AVRNNLAGAEELFARKFNALFAQGNYSEAAKVAANAPKGILRTPDTIRRFQSVPAQPGQT 410

Query: 426  PPLLQYFGTLLTRGKLNAFESLELSRLVVNQNKKNLLENWLAEDKLECSEELGDLVKTVD 485
             PLLQYFG LL +G+LN +ESLEL R V+ Q +K LLE WL EDKLECSEELGDLVK+VD
Sbjct: 411  SPLLQYFGILLDQGQLNKYESLELCRPVLQQGRKQLLEKWLKEDKLECSEELGDLVKSVD 470

Query: 486  NDLALKIYIKARATPKVVAAFAEKREFDKILIYSKQVGYTPDYLFLLQSILRTDPQGAVN 545
              LAL +Y++A    KV+  FAE  +  KI++Y+K+VGYTPD++FLL++++R  P     
Sbjct: 471  PTLALSVYLRANVPNKVIQCFAETGQVQKIVLYAKKVGYTPDWIFLLRNVMRISPDQGQQ 530

Query: 546  FALMMSQMEGGCPVDYNTITDLFLQRNLIREATAFLLDVLKPNLPEHGFLQTKVLEINLV 605
            FA M+ Q E     D   I D+F++ NLI++ TAFLLD LK N P  G LQT++LE+NL+
Sbjct: 531  FAQMLVQDEEPL-ADITQIVDVFMEYNLIQQCTAFLLDALKNNRPSEGPLQTRLLEMNLM 589

Query: 606  TFPNVADAILANGMFSHYDRPRIAQLCEKAGLYVRALQHYTELPDIKRVIVNTHAIEPQA 665
              P VADAIL N MF+HYDR  IAQLCEKAGL  RAL+H+T+L DIKR +V+TH + P+ 
Sbjct: 590  HAPQVADAILGNQMFTHYDRAHIAQLCEKAGLLQRALEHFTDLYDIKRAVVHTHLLNPEW 649

Query: 666  LVEFFGTLSKEWALECMKDLLLVNLRGNLQIIVQVAKEYCEQLGVDACIKIFEQFRSYEG 725
            LV +FG+LS E +LEC++ +L  N+R NLQI VQVA +Y EQL   + I++FE F+S+EG
Sbjct: 650  LVNYFGSLSVEDSLECLRAMLSANIRQNLQICVQVASKYHEQLSTQSLIELFESFKSFEG 709

Query: 726  LYFFLGSYLSSSEDPDIHFKYIEAAAKTGQIKEVERVTRESSFYDPEKTKNFLMEAKLPD 785
            L++FLGS ++ S+DPD+HFKYI+AA KTGQIKEVER+ RES+ YDPE+ KNFL EAKL D
Sbjct: 710  LFYFLGSIVNFSQDPDVHFKYIQAACKTGQIKEVERICRESNCYDPERVKNFLKEAKLTD 769

Query: 786  ARPLINVCDRFGFVPDLTHYLYTSNMLRYIEGYVQKVNPGNAPLVVGQLLDDECPEDFIK 845
              PLI VCDRF FV DL  YLY +N+ +YIE YVQKVNP   P+V+G LLD +C ED IK
Sbjct: 770  QLPLIIVCDRFDFVHDLVLYLYRNNLQKYIEIYVQKVNPSRLPVVIGGLLDVDCSEDVIK 829

Query: 846  GLILSVRSLLPVEPLVAECEKRNRLRLLTQFLEHLVSEGSQDVHVHNALGKIIIDSNNNP 905
             LIL VR     + LVAE EKRNRL+LL  +LE  + EG ++   HNAL KI IDSNNNP
Sbjct: 830  NLILVVRGQFSTDELVAEVEKRNRLKLLLPWLEARIHEGCEEPATHNALAKIYIDSNNNP 889

Query: 906  EHFLTTNPYYDSRVVGKYCEKRDPTLAVVAYRRGVCDDELINVTNKNSLFKLQARYVVER 965
            E FL  NPYYDSRVVGKYCEKRDP LA VAY RG CD ELINV N+NSLFK  +RY+V R
Sbjct: 890  ERFLRENPYYDSRVVGKYCEKRDPHLACVAYERGQCDLELINVCNENSLFKSLSRYLVRR 949

Query: 966  MDADLWEKVLNPDNTYRRQLIDQVVSTALPESKSPEQVSASVKAFMTADLPHELIELLEK 1025
             D +LW  VL   N YRR LIDQVV TAL E++ PE+VS +VKAFMTADLP+ELIELLEK
Sbjct: 950  KDPELWGSVLLESNPYRRPLIDQVVQTALSETQDPEEVSVTVKAFMTADLPNELIELLEK 1009

Query: 1026 IVLQNSAFSGNFNLQNLLILTAIKADSSRVMDYVNRLDNFDGPQVGEVAVEAELYEEAFA 1085
            IVL NS FS + NLQNLLILTAIKAD +RVM+Y+NRLDN+D P +  +A+  EL+EEAFA
Sbjct: 1010 IVLDNSVFSEHRNLQNLLILTAIKADRTRVMEYINRLDNYDAPDIANIAISNELFEEAFA 1069

Query: 1086 IFKKFNLNVQAVNVLLDNIHSIDRAVEFAFRVEEDAVWSQVAKAQLREGLVSDAIESFIR 1145
            IF+KF++N  AV VL+++I ++DRA EFA R  E AVWSQ+AKAQL++G+V +AI+S+I+
Sbjct: 1070 IFRKFDVNTSAVQVLIEHIGNLDRAYEFAERCNEPAVWSQLAKAQLQKGMVKEAIDSYIK 1129

Query: 1146 ADDATQFLDVIRAAQDGNAYQDLVRYLLMVRQKTKEPKVDSELIYAYAKIDRLSDIEEFI 1205
            ADD + +++V++AA     +++LV+YL M R+K +E  V++ELI+A AK +RL+++EEFI
Sbjct: 1130 ADDPSSYMEVVQAANTSGNWEELVKYLQMARKKARESYVETELIFALAKTNRLAELEEFI 1189

Query: 1206 LMPNVANLQNVGDRLYDEELYEAAKIIFAFISNWAKLAVTLVKLKQFQGAVDAARKANSA 1265
              PN A++Q VGDR YDE++Y+AAK+++  +SN+ +LA TLV L ++Q AVD ARKANS 
Sbjct: 1190 NGPNNAHIQQVGDRCYDEKMYDAAKLLYNNVSNFGRLASTLVHLGEYQAAVDGARKANST 1249

Query: 1266 KTWKEVCFACVDEEEFRLAQICGLNIIIQVDDLEEVSEYYQNRGCFNELISLMESGLGLE 1325
            +TWKEVCFACVD +EFRLAQ+CGL+I++  D+LEE+  YYQ+RG F ELI+++E+ LGLE
Sbjct: 1250 RTWKEVCFACVDGKEFRLAQMCGLHIVVHADELEELINYYQDRGYFEELITMLEAALGLE 1309

Query: 1326 RAHMGIFTELGVLYARYRPEKLMEHIKLFATRLNIPKLIRACDEQQHWKELTYLYIQYDE 1385
            RAHMG+FTEL +LY++++P+K+ EH++LF +R+NIPK++RA ++   W EL +LY +Y+E
Sbjct: 1310 RAHMGMFTELAILYSKFKPQKMREHLELFWSRVNIPKVLRAAEQAHLWAELVFLYDKYEE 1369

Query: 1386 FDNAATTIMNHSPEAWDHMQFKDVIAKVANVELYYKAVHFYLQEHPDLINDVLNVLALRV 1445
            +DNA  T+MNH  +AW   QFKD+I KVANVELYY+A+ FYL+  P L+ND+L VL+ R+
Sbjct: 1370 YDNAIITMMNHPTDAWKEGQFKDIITKVANVELYYRAIQFYLEFKPLLLNDLLMVLSPRL 1429

Query: 1446 DHARVVDIMRKAGHLRLVKPYMVAVQSNNVSAVNEALNEIYVEEEDYDRLRESIDLHDNF 1505
            DH R V+   K   L LVKPY+ +VQ++N  +VNE+LN +++ EEDY  LR SID +DNF
Sbjct: 1430 DHTRAVNYFSKVKQLPLVKPYLRSVQNHNNKSVNESLNNLFITEEDYQALRTSIDAYDNF 1489

Query: 1506 DQIGLAQKIEKHELLEMRRVAAYIYKKAGRWKQSIALSKKDNLYKDAMETASQSGERELA 1565
            D I LAQ++EKHEL+E RR+AAY++K   RWKQS+ L KKD+LYKDAM+ AS+S + ELA
Sbjct: 1490 DNISLAQRLEKHELIEFRRIAAYLFKGNNRWKQSVELCKKDSLYKDAMQYASESKDTELA 1549

Query: 1566 EELLVYFIDQGKKECFASCLFVCYDLIRVDVALELAWMHNMIDFAFPYLLQFIREYTGKV 1625
            EELL +F+ + K+ECF +CLF CYDL+R DV LE AW HN++DFA PY +Q ++EY  KV
Sbjct: 1550 EELLQWFLQEEKRECFGACLFTCYDLLRPDVVLETAWRHNIMDFAMPYFIQVMKEYLTKV 1609

Query: 1626 DELVKHKIESQNEVKAKEQEEKEVIAQQNMYAQLLPLALPAPPMPGMGGGMGGGYAPPPP 1685
            D     K+++   ++ +E++  E         QL+  A P+  +P           P  P
Sbjct: 1610 D-----KLDASESLRKEEEQATETQPIVYGQPQLMLTAGPSVAVP-----------PQAP 1653

Query: 1686 MGGGMGMPPMPPFGMPMGGY 1705
             G G      PP+G P  G+
Sbjct: 1654 FGYGY---TAPPYGQPQPGF 1670


>CLH_BOVIN (P49951) Clathrin heavy chain
          Length = 1675

 Score = 1889 bits (4894), Expect = 0.0
 Identities = 950/1701 (55%), Positives = 1254/1701 (72%), Gaps = 37/1701 (2%)

Query: 8    PILMREALTLPSIGINPQHITFTHVTMESDKYICVRE-TAPQNSVVIVDMNMPNQPLRRP 66
            PI  +E L L ++GINP +I F+ +TMESDK+IC+RE    Q  VVI+DMN P+ P+RRP
Sbjct: 6    PIRFQEHLQLQNLGINPANIGFSTLTMESDKFICIREKVGEQAQVVIIDMNDPSNPIRRP 65

Query: 67   ITADSALMNPNSRILALKAQLQGTTQDHLQIFNIELKAKMKSYQMPEQVVFWKWISPKLL 126
            I+ADSA+MNP S+++ALKA   G T   LQIFNIE+K+KMK++ M + V FWKWIS   +
Sbjct: 66   ISADSAIMNPASKVIALKA---GKT---LQIFNIEMKSKMKAHTMTDDVTFWKWISLNTV 119

Query: 127  GLVTQTSVYHWSIEGDSEPVKMFERTANLANNQIINYRCDPTEKWLVLIGIAPGSPERPQ 186
             LVT  +VYHWS+EG+S+PVKMF+R ++LA  QIINYR D  +KWL+L GI+     +  
Sbjct: 120  ALVTDNAVYHWSMEGESQPVKMFDRHSSLAGCQIINYRTDAKQKWLLLTGISA----QQN 175

Query: 187  LVKGNMQLFSVEQQRSQALEAHAASFAQFKVPGNENPSTLISFATKTVNAGQVISKLHVI 246
             V G MQL+SV+++ SQ +E HAASFAQFK+ GN   STL  FA +    GQ   KLH+I
Sbjct: 176  RVVGAMQLYSVDRKVSQPIEGHAASFAQFKMEGNAEESTLFCFAVR----GQAGGKLHII 231

Query: 247  ELGAQP-GKPSFTKKQADLFFPPDFADDFPVSMQISHKYSLIYVITKLGLLFVYDLETAT 305
            E+G  P G   F KK  D+FFPP+  +DFPV+MQIS K+ ++++ITK G + +YDLET T
Sbjct: 232  EVGTPPTGNQPFPKKAVDVFFPPEAQNDFPVAMQISEKHDVVFLITKYGYIHLYDLETGT 291

Query: 306  AVYRNRISPDPIFLTSEATSVGGFYAINRRGQVLLATVNEQTIVNFVSGQLNNLELAVNL 365
             +Y NRIS + IF+T+   +  G   +NR+GQVL   V E+ I+ +++  L N +LA+ +
Sbjct: 292  CIYMNRISGETIFVTAPHEATAGIIGVNRKGQVLSVCVEEENIIPYITNVLQNPDLALRM 351

Query: 366  AKRGNLPGAEKLVVERFHELFAQTKYKEAAELAAESPQGILRTPDTVAKFQSVPVQAGQT 425
            A R NL GAE+L   +F+ LFAQ  Y EAA++AA +P+GILRTPDT+ +FQSVP Q GQT
Sbjct: 352  AVRNNLAGAEELFARKFNALFAQGNYSEAAKVAANAPKGILRTPDTIRRFQSVPAQPGQT 411

Query: 426  PPLLQYFGTLLTRGKLNAFESLELSRLVVNQNKKNLLENWLAEDKLECSEELGDLVKTVD 485
             PLLQYFG LL +G+LN +ESLEL R V+ Q +K LLE WL EDKLECSEELGDLVK+VD
Sbjct: 412  SPLLQYFGILLDQGQLNKYESLELCRPVLQQGRKQLLEKWLKEDKLECSEELGDLVKSVD 471

Query: 486  NDLALKIYIKARATPKVVAAFAEKREFDKILIYSKQVGYTPDYLFLLQSILRTDPQGAVN 545
              LAL +Y++A    KV+  FAE  +  KI++Y+K+VGYTPD++FLL++++R  P     
Sbjct: 472  PTLALSVYLRANVPNKVIQCFAETGQVQKIVLYAKKVGYTPDWIFLLRNVMRISPDQGQQ 531

Query: 546  FALMMSQMEGGCPVDYNTITDLFLQRNLIREATAFLLDVLKPNLPEHGFLQTKVLEINLV 605
            FA M+ Q E     D   I D+F++ NLI++ TAFLLD LK N P  G LQT++LE+NL+
Sbjct: 532  FAQMLVQDEEPL-ADITQIVDVFMEYNLIQQCTAFLLDALKNNRPSEGPLQTRLLEMNLM 590

Query: 606  TFPNVADAILANGMFSHYDRPRIAQLCEKAGLYVRALQHYTELPDIKRVIVNTHAIEPQA 665
              P VADAIL N MF+HYDR  IAQLCEKAGL  RAL+H+T+L DIKR +V+TH + P+ 
Sbjct: 591  HAPQVADAILGNQMFTHYDRAHIAQLCEKAGLLQRALEHFTDLYDIKRAVVHTHLLNPEW 650

Query: 666  LVEFFGTLSKEWALECMKDLLLVNLRGNLQIIVQVAKEYCEQLGVDACIKIFEQFRSYEG 725
            LV +FG+LS E +LEC++ +L  N+R NLQI VQVA +Y EQL   + I++FE F+S+EG
Sbjct: 651  LVNYFGSLSVEDSLECLRAMLSANIRQNLQICVQVASKYHEQLSTQSLIELFESFKSFEG 710

Query: 726  LYFFLGSYLSSSEDPDIHFKYIEAAAKTGQIKEVERVTRESSFYDPEKTKNFLMEAKLPD 785
            L++FLGS ++ S+DPD+HFKYI+AA KTGQIKEVER+ RES+ YDPE+ KNFL EAKL D
Sbjct: 711  LFYFLGSIVNFSQDPDVHFKYIQAACKTGQIKEVERICRESNCYDPERVKNFLKEAKLTD 770

Query: 786  ARPLINVCDRFGFVPDLTHYLYTSNMLRYIEGYVQKVNPGNAPLVVGQLLDDECPEDFIK 845
              PLI VCDRF FV DL  YLY +N+ +YIE YVQKVNP   P+V+G LLD +C ED IK
Sbjct: 771  QLPLIIVCDRFDFVHDLVLYLYRNNLQKYIEIYVQKVNPSRLPVVIGGLLDVDCSEDVIK 830

Query: 846  GLILSVRSLLPVEPLVAECEKRNRLRLLTQFLEHLVSEGSQDVHVHNALGKIIIDSNNNP 905
             LIL VR     + LVAE EKRNRL+LL  +LE  + EG ++   HNAL KI IDSNNNP
Sbjct: 831  NLILVVRGQFSTDELVAEVEKRNRLKLLLPWLEARIHEGCEEPATHNALAKIYIDSNNNP 890

Query: 906  EHFLTTNPYYDSRVVGKYCEKRDPTLAVVAYRRGVCDDELINVTNKNSLFKLQARYVVER 965
            E FL  NPYYDSRVVGKYCEKRDP LA VAY RG CD ELINV N+NSLFK  +RY+V R
Sbjct: 891  ERFLRENPYYDSRVVGKYCEKRDPHLACVAYERGQCDLELINVCNENSLFKSLSRYLVRR 950

Query: 966  MDADLWEKVLNPDNTYRRQLIDQVVSTALPESKSPEQVSASVKAFMTADLPHELIELLEK 1025
             D +LW  VL   N YRR LIDQVV TAL E++ PE+VS +VKAFMTADLP+ELIELLEK
Sbjct: 951  KDPELWGSVLLESNPYRRPLIDQVVQTALSETQDPEEVSVTVKAFMTADLPNELIELLEK 1010

Query: 1026 IVLQNSAFSGNFNLQNLLILTAIKADSSRVMDYVNRLDNFDGPQVGEVAVEAELYEEAFA 1085
            IVL NS FS + NLQNLLILTAIKAD +RVM+Y+NRLDN+D P +  +A+  EL+EEAFA
Sbjct: 1011 IVLDNSVFSEHRNLQNLLILTAIKADRTRVMEYINRLDNYDAPDIANIAISNELFEEAFA 1070

Query: 1086 IFKKFNLNVQAVNVLLDNIHSIDRAVEFAFRVEEDAVWSQVAKAQLREGLVSDAIESFIR 1145
            IF+KF++N  AV VL+++I ++DRA EFA R  E AVWSQ+AKAQL++G+V +AI+S+I+
Sbjct: 1071 IFRKFDVNTSAVQVLIEHIGNLDRAYEFAERCNEPAVWSQLAKAQLQKGMVKEAIDSYIK 1130

Query: 1146 ADDATQFLDVIRAAQDGNAYQDLVRYLLMVRQKTKEPKVDSELIYAYAKIDRLSDIEEFI 1205
            ADD + +++V++AA     +++LV+YL M R+K +E  V++ELI+A AK +RL+++EEFI
Sbjct: 1131 ADDPSSYMEVVQAANTSGNWEELVKYLQMARKKARESYVETELIFALAKTNRLAELEEFI 1190

Query: 1206 LMPNVANLQNVGDRLYDEELYEAAKIIFAFISNWAKLAVTLVKLKQFQGAVDAARKANSA 1265
              PN A++Q VGDR YDE++Y+AAK+++  +SN+ +LA TLV L ++Q AVD ARKANS 
Sbjct: 1191 NGPNNAHIQQVGDRCYDEKMYDAAKLLYNNVSNFGRLASTLVHLGEYQAAVDGARKANST 1250

Query: 1266 KTWKEVCFACVDEEEFRLAQICGLNIIIQVDDLEEVSEYYQNRGCFNELISLMESGLGLE 1325
            +TWKEVCFACVD +EFRLAQ+CGL+I++  D+LEE+  YYQ+RG F ELI+++E+ LGLE
Sbjct: 1251 RTWKEVCFACVDGKEFRLAQMCGLHIVVHADELEELINYYQDRGYFEELITMLEAALGLE 1310

Query: 1326 RAHMGIFTELGVLYARYRPEKLMEHIKLFATRLNIPKLIRACDEQQHWKELTYLYIQYDE 1385
            RAHMG+FTEL +LY++++P+K+ EH++LF +R+NIPK++RA ++   W EL +LY +Y+E
Sbjct: 1311 RAHMGMFTELAILYSKFKPQKMREHLELFWSRVNIPKVLRAAEQAHLWAELVFLYDKYEE 1370

Query: 1386 FDNAATTIMNHSPEAWDHMQFKDVIAKVANVELYYKAVHFYLQEHPDLINDVLNVLALRV 1445
            +DNA  T+MNH  +AW   QFKD+I KVANVELYY+A+ FYL+  P L+ND+L VL+ R+
Sbjct: 1371 YDNAIITMMNHPTDAWKEGQFKDIITKVANVELYYRAIQFYLEFKPLLLNDLLMVLSPRL 1430

Query: 1446 DHARVVDIMRKAGHLRLVKPYMVAVQSNNVSAVNEALNEIYVEEEDYDRLRESIDLHDNF 1505
            DH R V+   K   L LVKPY+ +VQ++N  +VNE+LN +++ EEDY  LR SID +DNF
Sbjct: 1431 DHTRAVNYFSKVKQLPLVKPYLRSVQNHNNKSVNESLNNLFITEEDYQALRTSIDAYDNF 1490

Query: 1506 DQIGLAQKIEKHELLEMRRVAAYIYKKAGRWKQSIALSKKDNLYKDAMETASQSGERELA 1565
            D I LAQ++EKHEL+E RR+AAY++K   RWKQS+ L KKD+LYKDAM+ AS+S + ELA
Sbjct: 1491 DNISLAQRLEKHELIEFRRIAAYLFKGNNRWKQSVELCKKDSLYKDAMQYASESKDTELA 1550

Query: 1566 EELLVYFIDQGKKECFASCLFVCYDLIRVDVALELAWMHNMIDFAFPYLLQFIREYTGKV 1625
            EELL +F+ + K+ECF +CLF CYDL+R DV LE AW HN++DFA PY +Q ++EY  KV
Sbjct: 1551 EELLQWFLQEEKRECFGACLFTCYDLLRPDVVLETAWRHNIMDFAMPYFIQVMKEYLTKV 1610

Query: 1626 DELVKHKIESQNEVKAKEQEEKEVIAQQNMYAQLLPLALPAPPMPGMGGGMGGGYAPPPP 1685
            D     K+++   ++ +E++  E         QL+  A P+  +P           P  P
Sbjct: 1611 D-----KLDASESLRKEEEQATETQPIVYGQPQLMLTAGPSVAVP-----------PQAP 1654

Query: 1686 MGGGMGMP----PMPPFGMPM 1702
             G G   P    P P FG  M
Sbjct: 1655 FGYGYTAPAYGQPQPGFGYSM 1675


>CLH_RAT (P11442) Clathrin heavy chain
          Length = 1675

 Score = 1887 bits (4887), Expect = 0.0
 Identities = 948/1700 (55%), Positives = 1254/1700 (73%), Gaps = 36/1700 (2%)

Query: 8    PILMREALTLPSIGINPQHITFTHVTMESDKYICVRE-TAPQNSVVIVDMNMPNQPLRRP 66
            PI  +E L L ++GINP +I F+ +TMESDK+IC+RE    Q  VVI+DMN P+ P+RRP
Sbjct: 6    PIRFQEHLQLQNLGINPANIGFSTLTMESDKFICIREKVGEQAQVVIIDMNDPSNPIRRP 65

Query: 67   ITADSALMNPNSRILALKAQLQGTTQDHLQIFNIELKAKMKSYQMPEQVVFWKWISPKLL 126
            I+ADSA+MNP S+++ALKA   G T   LQIFNIE+K+KMK++ M + V FWKWIS   +
Sbjct: 66   ISADSAIMNPASKVIALKA---GKT---LQIFNIEMKSKMKAHTMTDDVTFWKWISLNTV 119

Query: 127  GLVTQTSVYHWSIEGDSEPVKMFERTANLANNQIINYRCDPTEKWLVLIGIAPGSPERPQ 186
             LVT  +VYHWS+EG+S+PVKMF+R ++LA  QIINYR D  +KWL+L GI+     +  
Sbjct: 120  ALVTDNAVYHWSMEGESQPVKMFDRHSSLAGCQIINYRTDAKQKWLLLTGISA----QQN 175

Query: 187  LVKGNMQLFSVEQQRSQALEAHAASFAQFKVPGNENPSTLISFATKTVNAGQVISKLHVI 246
             V G MQL+SV+++ SQ +E HAASFAQFK+ GN   STL  FA +    GQ   KLH+I
Sbjct: 176  RVVGAMQLYSVDRKVSQPIEGHAASFAQFKMEGNAEESTLFCFAVR----GQAGGKLHII 231

Query: 247  ELGAQP-GKPSFTKKQADLFFPPDFADDFPVSMQISHKYSLIYVITKLGLLFVYDLETAT 305
            E+G  P G   F KK  D+FFPP+  +DFPV+MQIS K+ ++++ITK G + +YDLET T
Sbjct: 232  EVGTPPTGNQPFPKKAVDVFFPPEAQNDFPVAMQISEKHDVVFLITKYGYIHLYDLETGT 291

Query: 306  AVYRNRISPDPIFLTSEATSVGGFYAINRRGQVLLATVNEQTIVNFVSGQLNNLELAVNL 365
             +Y NRIS + IF+T+   +  G   +NR+GQVL   V E+ I+ +++  L N +LA+ +
Sbjct: 292  CIYMNRISGETIFVTAPHEATAGIIGVNRKGQVLSVCVEEENIIPYITNVLQNPDLALRM 351

Query: 366  AKRGNLPGAEKLVVERFHELFAQTKYKEAAELAAESPQGILRTPDTVAKFQSVPVQAGQT 425
            A R NL GAE+L   +F+ LFAQ  Y EAA++AA +P+GILRTPDT+ +FQSVP Q GQT
Sbjct: 352  AVRNNLAGAEELFARKFNALFAQGNYSEAAKVAANAPKGILRTPDTIRRFQSVPAQPGQT 411

Query: 426  PPLLQYFGTLLTRGKLNAFESLELSRLVVNQNKKNLLENWLAEDKLECSEELGDLVKTVD 485
             PLLQYFG LL +G+LN +ESLEL R V+ Q +K LLE WL EDKLECSEELGDLVK+VD
Sbjct: 412  SPLLQYFGILLDQGQLNKYESLELCRPVLQQGRKQLLEKWLKEDKLECSEELGDLVKSVD 471

Query: 486  NDLALKIYIKARATPKVVAAFAEKREFDKILIYSKQVGYTPDYLFLLQSILRTDPQGAVN 545
              LAL +Y++A    KV+  FAE  +  KI++Y+K+VGYTPD++FLL++++R  P     
Sbjct: 472  PTLALSVYLRANVPNKVIQCFAETGQVQKIVLYAKKVGYTPDWIFLLRNVMRISPDQGQQ 531

Query: 546  FALMMSQMEGGCPVDYNTITDLFLQRNLIREATAFLLDVLKPNLPEHGFLQTKVLEINLV 605
            FA M+ Q E     D   I D+F++ NLI++ TAFLLD LK N P  G LQT++LE+NL+
Sbjct: 532  FAQMLVQDEEPL-ADITQIVDVFMEYNLIQQCTAFLLDALKNNRPSEGPLQTRLLEMNLM 590

Query: 606  TFPNVADAILANGMFSHYDRPRIAQLCEKAGLYVRALQHYTELPDIKRVIVNTHAIEPQA 665
              P VADAIL N MF+HYDR  IAQLCEKAGL  RAL+H+T+L DIKR +V+TH + P+ 
Sbjct: 591  HAPQVADAILGNQMFTHYDRAHIAQLCEKAGLLQRALEHFTDLYDIKRAVVHTHLLNPEW 650

Query: 666  LVEFFGTLSKEWALECMKDLLLVNLRGNLQIIVQVAKEYCEQLGVDACIKIFEQFRSYEG 725
            LV +FG+LS E +LEC++ +L  N+R NLQI VQVA +Y EQL   + I++FE F+S+EG
Sbjct: 651  LVNYFGSLSVEDSLECLRAMLSANIRQNLQIWVQVASKYHEQLSTQSLIELFESFKSFEG 710

Query: 726  LYFFLGSYLSSSEDPDIHFKYIEAAAKTGQIKEVERVTRESSFYDPEKTKNFLMEAKLPD 785
            L++FLGS ++ S+DPD+HFKYI+AA KTGQIKEVER+ RES+ YDPE+ KNFL EAKL D
Sbjct: 711  LFYFLGSIVNFSQDPDVHFKYIQAACKTGQIKEVERICRESNCYDPERVKNFLKEAKLTD 770

Query: 786  ARPLINVCDRFGFVPDLTHYLYTSNMLRYIEGYVQKVNPGNAPLVVGQLLDDECPEDFIK 845
              PLI VCDRF FV DL  YLY +++ +YIE YVQKVNP   P+V+G LLD +C ED IK
Sbjct: 771  QLPLIIVCDRFDFVHDLVLYLYRNSLQKYIEIYVQKVNPSRLPVVIGGLLDVDCSEDVIK 830

Query: 846  GLILSVRSLLPVEPLVAECEKRNRLRLLTQFLEHLVSEGSQDVHVHNALGKIIIDSNNNP 905
             LIL VR     + LVAE EKRNRL+LL  +LE  + EG ++   HNAL KI IDSNNNP
Sbjct: 831  NLILVVRGQFSTDELVAEVEKRNRLKLLLPWLEARIHEGCEEPATHNALAKIYIDSNNNP 890

Query: 906  EHFLTTNPYYDSRVVGKYCEKRDPTLAVVAYRRGVCDDELINVTNKNSLFKLQARYVVER 965
            E FL  NPYYDSRVVGKYCEKRDP LA VAY RG CD ELINV N+NSLFK  +RY+V R
Sbjct: 891  ERFLRENPYYDSRVVGKYCEKRDPHLACVAYERGQCDLELINVCNENSLFKSLSRYLVRR 950

Query: 966  MDADLWEKVLNPDNTYRRQLIDQVVSTALPESKSPEQVSASVKAFMTADLPHELIELLEK 1025
             D +LW  VL   N YRR LIDQVV TAL E++ PE+VS +VKAFMTADLP+ELIELLEK
Sbjct: 951  KDPELWGSVLLESNPYRRPLIDQVVQTALSETQDPEEVSVTVKAFMTADLPNELIELLEK 1010

Query: 1026 IVLQNSAFSGNFNLQNLLILTAIKADSSRVMDYVNRLDNFDGPQVGEVAVEAELYEEAFA 1085
            IVL NS FS + NLQNLLILTAIKAD +RVM+Y+NRLDN+D P +  +A+  EL+EEAFA
Sbjct: 1011 IVLDNSVFSEHRNLQNLLILTAIKADRTRVMEYINRLDNYDAPDIANIAISNELFEEAFA 1070

Query: 1086 IFKKFNLNVQAVNVLLDNIHSIDRAVEFAFRVEEDAVWSQVAKAQLREGLVSDAIESFIR 1145
            IF+KF++N  AV VL+++I ++DRA EFA R  E AVWSQ+AKAQL++G+V +AI+S+I+
Sbjct: 1071 IFRKFDVNTSAVQVLIEHIGNLDRAYEFAERCNEPAVWSQLAKAQLQKGMVKEAIDSYIK 1130

Query: 1146 ADDATQFLDVIRAAQDGNAYQDLVRYLLMVRQKTKEPKVDSELIYAYAKIDRLSDIEEFI 1205
            ADD + +++V++AA     +++LV+YL M R+K +E  V++ELI+A AK +RL+++EEFI
Sbjct: 1131 ADDPSSYMEVVQAANTSGNWEELVKYLQMARKKARESYVETELIFALAKTNRLAELEEFI 1190

Query: 1206 LMPNVANLQNVGDRLYDEELYEAAKIIFAFISNWAKLAVTLVKLKQFQGAVDAARKANSA 1265
              PN A++Q VGDR YDE++Y+AAK+++  +SN+ +LA TLV L ++Q AVD ARKANS 
Sbjct: 1191 NGPNNAHIQQVGDRCYDEKMYDAAKLLYNNVSNFGRLASTLVHLGEYQAAVDGARKANST 1250

Query: 1266 KTWKEVCFACVDEEEFRLAQICGLNIIIQVDDLEEVSEYYQNRGCFNELISLMESGLGLE 1325
            +TWKEVCFACVD +EFRLAQ+CGL+I++  D+LEE+  YYQ+RG F ELI+++E+ LGLE
Sbjct: 1251 RTWKEVCFACVDGKEFRLAQMCGLHIVVHADELEELINYYQDRGYFEELITMLEAALGLE 1310

Query: 1326 RAHMGIFTELGVLYARYRPEKLMEHIKLFATRLNIPKLIRACDEQQHWKELTYLYIQYDE 1385
            RAHMG+FTEL +LY++++P+K+ EH++LF +R+NIPK++RA ++   W EL +LY +Y+E
Sbjct: 1311 RAHMGMFTELAILYSKFKPQKMREHLELFWSRVNIPKVLRAAEQAHLWAELVFLYDKYEE 1370

Query: 1386 FDNAATTIMNHSPEAWDHMQFKDVIAKVANVELYYKAVHFYLQEHPDLINDVLNVLALRV 1445
            +DNA  T+MNH  +AW   QFKD+I KVANVELYYKA+ FYL+  P L+ND+L VL+ R+
Sbjct: 1371 YDNAIITMMNHPTDAWKEGQFKDIITKVANVELYYKAIQFYLEFKPLLLNDLLMVLSPRL 1430

Query: 1446 DHARVVDIMRKAGHLRLVKPYMVAVQSNNVSAVNEALNEIYVEEEDYDRLRESIDLHDNF 1505
             H R V+   K   L LVKPY+ +VQ++N  +VNE+LN +++ EEDY  LR SID +DNF
Sbjct: 1431 AHTRAVNYFSKVKQLPLVKPYLRSVQNHNNKSVNESLNNLFITEEDYQALRTSIDAYDNF 1490

Query: 1506 DQIGLAQKIEKHELLEMRRVAAYIYKKAGRWKQSIALSKKDNLYKDAMETASQSGERELA 1565
            D I LAQ++EKHEL+E RR+AAY++K   RWKQS+ L KKD+LYKDAM+ AS+S + ELA
Sbjct: 1491 DNISLAQRLEKHELIEFRRIAAYLFKGNNRWKQSVELCKKDSLYKDAMQYASESKDTELA 1550

Query: 1566 EELLVYFIDQGKKECFASCLFVCYDLIRVDVALELAWMHNMIDFAFPYLLQFIREYTGKV 1625
            EELL +F+ + K+ECF +CLF CYDL+R DV LE AW HN++DFA PY +Q ++EY  KV
Sbjct: 1551 EELLQWFLQEEKRECFGACLFTCYDLLRPDVVLETAWRHNIMDFAMPYFIQVMKEYLTKV 1610

Query: 1626 DELVKHKIESQNEVKAKEQEEKEVIAQQNMYAQLLPLALPAPPMPGMGGGMGGGYAPPPP 1685
            D     K+++   ++ +E++  E         QL+  A P+  +P           P  P
Sbjct: 1611 D-----KLDASESLRKEEEQATETQPIVYGQPQLMLTAGPSVAVP-----------PQAP 1654

Query: 1686 MGGGMGMPPMPPFGMPMGGY 1705
             G G      PP+G P  G+
Sbjct: 1655 FGYGY---TAPPYGQPQPGF 1671


>CLH_DROME (P29742) Clathrin heavy chain
          Length = 1678

 Score = 1881 bits (4873), Expect = 0.0
 Identities = 949/1666 (56%), Positives = 1238/1666 (73%), Gaps = 23/1666 (1%)

Query: 8    PILMREALTLPSIGINPQHITFTHVTMESDKYICVRETAPQNS-VVIVDMNMPNQPLRRP 66
            PI  +E L L ++GIN    +F+ +TMESDK+ICVRE     + VVI+DMN    P RRP
Sbjct: 6    PIRFQEHLQLTNVGINANSFSFSTLTMESDKFICVREKVNDTAQVVIIDMNDATNPTRRP 65

Query: 67   ITADSALMNPNSRILALKAQLQGTTQDHLQIFNIELKAKMKSYQMPEQVVFWKWISPKLL 126
            I+ADSA+MNP S+++ALKAQ        LQIFNIE+K+KMK++ M E VVFWKWIS   L
Sbjct: 66   ISADSAIMNPASKVIALKAQKT------LQIFNIEMKSKMKAHTMNEDVVFWKWISLNTL 119

Query: 127  GLVTQTSVYHWSIEGDSEPVKMFERTANLANNQIINYRCDPTEKWLVLIGIAPGSPERPQ 186
             LVT+TSV+HWS+EGDS P KMF+R ++L   QIINYRC+ +++WL+L+GI+      P 
Sbjct: 120  ALVTETSVFHWSMEGDSMPQKMFDRHSSLNGCQIINYRCNASQQWLLLVGISA----LPS 175

Query: 187  LVKGNMQLFSVEQQRSQALEAHAASFAQFKVPGNENPSTLISFATKTVNAGQVISKLHVI 246
             V G MQL+SVE++ SQA+E HAASFA FK+  N+ P+TL  FA +T   G    KLH+I
Sbjct: 176  RVAGAMQLYSVERKVSQAIEGHAASFATFKIDANKEPTTLFCFAVRTATGG----KLHII 231

Query: 247  ELGAQP-GKPSFTKKQADLFFPPDFADDFPVSMQISHKYSLIYVITKLGLLFVYDLETAT 305
            E+GA P G   F KK  D+FFPP+  +DFPV+MQ+S KY  IY+ITK G + +YD+ETAT
Sbjct: 232  EVGAPPNGNQPFAKKAVDVFFPPEAQNDFPVAMQVSAKYDTIYLITKYGYIHLYDMETAT 291

Query: 306  AVYRNRISPDPIFLTSEATSVGGFYAINRRGQVLLATVNEQTIVNFVSGQLNNLELAVNL 365
             +Y NRIS D IF+T+   + GG   +NR+GQVL  TV+E+ I+ +++  L N +LA+ +
Sbjct: 292  CIYMNRISADTIFVTAPHEASGGIIGVNRKGQVLSVTVDEEQIIPYINTVLQNPDLALRM 351

Query: 366  AKRGNLPGAEKLVVERFHELFAQTKYKEAAELAAESPQGILRTPDTVAKFQSVPVQAGQT 425
            A R NL GAE L V +F++LF   +Y EAA++AA +P+ ILRTP T+ +FQ V   AG T
Sbjct: 352  AVRNNLAGAEDLFVRKFNKLFTAGQYAEAAKVAALAPKAILRTPQTIQRFQQVQTPAGST 411

Query: 426  -PPLLQYFGTLLTRGKLNAFESLELSRLVVNQNKKNLLENWLAEDKLECSEELGDLVKTV 484
             PPLLQYFG LL +GKLN FESLEL R V+ Q KK L E WL E+KLECSEELGDLVK  
Sbjct: 412  TPPLLQYFGILLDQGKLNKFESLELCRPVLLQGKKQLCEKWLKEEKLECSEELGDLVKAS 471

Query: 485  DNDLALKIYIKARATPKVVAAFAEKREFDKILIYSKQVGYTPDYLFLLQSILRTDPQGAV 544
            D  LAL IY++A    KV+  FAE  +F KI++Y+K+V YTPDY+FLL+S++R++P+   
Sbjct: 472  DLTLALSIYLRANVPNKVIQCFAETGQFQKIVLYAKKVNYTPDYVFLLRSVMRSNPEQGA 531

Query: 545  NFALMMSQMEGGCPVDYNTITDLFLQRNLIREATAFLLDVLKPNLPEHGFLQTKVLEINL 604
             FA M+   E     D N I D+F++ +++++ TAFLLD LK N P  G LQT++LE+NL
Sbjct: 532  GFASMLVAEEEPL-ADINQIVDIFMEHSMVQQCTAFLLDALKHNRPAEGALQTRLLEMNL 590

Query: 605  VTFPNVADAILANGMFSHYDRPRIAQLCEKAGLYVRALQHYTELPDIKRVIVNTHAIEPQ 664
            ++ P VADAIL N MF+HYDR  IAQLCEKAGL  RAL+HYT+L DIKR +V+TH +  +
Sbjct: 591  MSAPQVADAILGNAMFTHYDRAHIAQLCEKAGLLQRALEHYTDLYDIKRAVVHTHMLNAE 650

Query: 665  ALVEFFGTLSKEWALECMKDLLLVNLRGNLQIIVQVAKEYCEQLGVDACIKIFEQFRSYE 724
             LV FFGTLS E +LEC+K +L  NLR NLQI VQ+A +Y EQL   A I +FE F+SY+
Sbjct: 651  WLVSFFGTLSVEDSLECLKAMLTANLRQNLQICVQIATKYHEQLTNKALIDLFEGFKSYD 710

Query: 725  GLYFFLGSYLSSSEDPDIHFKYIEAAAKTGQIKEVERVTRESSFYDPEKTKNFLMEAKLP 784
            GL++FL S ++ S+DP++HFKYI+AA KT QIKEVER+ RES+ Y+PE+ KNFL EAKL 
Sbjct: 711  GLFYFLSSIVNFSQDPEVHFKYIQAACKTNQIKEVERICRESNCYNPERVKNFLKEAKLT 770

Query: 785  DARPLINVCDRFGFVPDLTHYLYTSNMLRYIEGYVQKVNPGNAPLVVGQLLDDECPEDFI 844
            D  PLI VCDRF FV DL  YLY +N+ +YIE YVQKVNP   P+VVG LLD +C ED I
Sbjct: 771  DQLPLIIVCDRFDFVHDLVLYLYRNNLQKYIEIYVQKVNPSRLPVVVGGLLDVDCSEDII 830

Query: 845  KGLILSVRSLLPVEPLVAECEKRNRLRLLTQFLEHLVSEGSQDVHVHNALGKIIIDSNNN 904
            K LIL V+     + LV E EKRNRL+LL  +LE  V EG  +   HNAL KI IDSNNN
Sbjct: 831  KNLILVVKGQFSTDELVEEVEKRNRLKLLLPWLESRVHEGCVEPATHNALAKIYIDSNNN 890

Query: 905  PEHFLTTNPYYDSRVVGKYCEKRDPTLAVVAYRRGVCDDELINVTNKNSLFKLQARYVVE 964
            PE +L  N YYDSRVVG+YCEKRDP LA VAY RG+CD ELI V N+NSLFK +ARY+V 
Sbjct: 891  PERYLKENQYYDSRVVGRYCEKRDPHLACVAYERGLCDRELIAVCNENSLFKSEARYLVG 950

Query: 965  RMDADLWEKVLNPDNTYRRQLIDQVVSTALPESKSPEQVSASVKAFMTADLPHELIELLE 1024
            R DA+LW +VL+  N Y+RQLIDQVV TAL E++ P+ +S +VKAFMTADLP+ELIELLE
Sbjct: 951  RRDAELWAEVLSESNPYKRQLIDQVVQTALSETQDPDDISVTVKAFMTADLPNELIELLE 1010

Query: 1025 KIVLQNSAFSGNFNLQNLLILTAIKADSSRVMDYVNRLDNFDGPQVGEVAVEAELYEEAF 1084
            KI+L +S FS + NLQNLLILTAIKAD +RVMDY+NRL+N+D P +  +A+  +LYEEAF
Sbjct: 1011 KIILDSSVFSDHRNLQNLLILTAIKADRTRVMDYINRLENYDAPDIANIAISNQLYEEAF 1070

Query: 1085 AIFKKFNLNVQAVNVLLDNIHSIDRAVEFAFRVEEDAVWSQVAKAQLREGLVSDAIESFI 1144
            AIFKKF++N  A+ VL+D +++++RA EFA R  E AVWSQ+AKAQL++GLV +AI+S+I
Sbjct: 1071 AIFKKFDVNTSAIQVLIDQVNNLERANEFAERCNEPAVWSQLAKAQLQQGLVKEAIDSYI 1130

Query: 1145 RADDATQFLDVIRAAQDGNAYQDLVRYLLMVRQKTKEPKVDSELIYAYAKIDRLSDIEEF 1204
            +ADD + ++DV+  A    ++ DLVRYL M R+K +E  ++SELIYAYA+  RL+D+EEF
Sbjct: 1131 KADDPSAYVDVVDVASKVESWDDLVRYLQMARKKARESYIESELIYAYARTGRLADLEEF 1190

Query: 1205 ILMPNVANLQNVGDRLYDEELYEAAKIIFAFISNWAKLAVTLVKLKQFQGAVDAARKANS 1264
            I  PN A++Q +G+R + + +Y+AAK+++  +SN+A+LA+TLV LK+FQGAVD+ARKANS
Sbjct: 1191 ISGPNHADIQKIGNRCFSDGMYDAAKLLYNNVSNFARLAITLVYLKEFQGAVDSARKANS 1250

Query: 1265 AKTWKEVCFACVDEEEFRLAQICGLNIIIQVDDLEEVSEYYQNRGCFNELISLMESGLGL 1324
             +TWKEVCFACVD EEFRLAQ+CGL+I++  D+LE++  YYQNRG F+ELI+L+ES LGL
Sbjct: 1251 TRTWKEVCFACVDAEEFRLAQMCGLHIVVHADELEDLINYYQNRGYFDELIALLESALGL 1310

Query: 1325 ERAHMGIFTELGVLYARYRPEKLMEHIKLFATRLNIPKLIRACDEQQHWKELTYLYIQYD 1384
            ERAHMG+FTEL +LY++++P K+ EH++LF +R+NIPK++RA +    W EL +LY +Y+
Sbjct: 1311 ERAHMGMFTELAILYSKFKPSKMREHLELFWSRVNIPKVLRAAESAHLWSELVFLYDKYE 1370

Query: 1385 EFDNAATTIMNHSPEAWDHMQFKDVIAKVANVELYYKAVHFYLQEHPDLINDVLNVLALR 1444
            E+DNA   +M H  EAW    FKD+I KVAN+ELYYKA+ FYL   P L+ND+L VLA R
Sbjct: 1371 EYDNAVLAMMAHPTEAWREGHFKDIITKVANIELYYKAIEFYLDFKPLLLNDMLLVLAPR 1430

Query: 1445 VDHARVVDIMRKAGHLRLVKPYMVAVQSNNVSAVNEALNEIYVEEEDYDRLRESIDLHDN 1504
            +DH R V    K G+L LVKPY+ +VQS N  A+NEALN + ++EEDY  LR SID  DN
Sbjct: 1431 MDHTRAVSYFSKTGYLPLVKPYLRSVQSLNNKAINEALNGLLIDEEDYQGLRNSIDGFDN 1490

Query: 1505 FDQIGLAQKIEKHELLEMRRVAAYIYKKAGRWKQSIALSKKDNLYKDAMETASQSGEREL 1564
            FD I LAQK+EKHEL E RR+AAY+YK   RWKQS+ L KKD LYKDAME A++S ++++
Sbjct: 1491 FDNIALAQKLEKHELTEFRRIAAYLYKGNNRWKQSVELCKKDKLYKDAMEYAAESCKQDI 1550

Query: 1565 AEELLVYFIDQGKKECFASCLFVCYDLIRVDVALELAWMHNMIDFAFPYLLQFIREYTGK 1624
            AEELL +F+++   +CFA+CL+ CYDL+R DV LELAW H ++DFA PYL+Q +REYT K
Sbjct: 1551 AEELLGWFLERDAYDCFAACLYQCYDLLRPDVILELAWKHKIVDFAMPYLIQVLREYTTK 1610

Query: 1625 VDELVKHKIESQNEVKAKEQEEKEVIAQQNMYAQLLPLALPAPPMP 1670
            VD+L  +  E+Q E +    E K +I    M  QL+  A PA  +P
Sbjct: 1611 VDKLELN--EAQREKEDDSTEHKNII---QMEPQLMITAGPAMGIP 1651


>CLH2_HUMAN (P53675) Clathrin heavy chain 2 (CLH-22)
          Length = 1640

 Score = 1825 bits (4728), Expect = 0.0
 Identities = 909/1624 (55%), Positives = 1211/1624 (73%), Gaps = 19/1624 (1%)

Query: 8    PILMREALTLPSIGINPQHITFTHVTMESDKYICVRE-TAPQNSVVIVDMNMPNQPLRRP 66
            P+  +E   L ++GINP +I F+ +TMESDK+IC+RE    Q  V I+DM+ P  P+RRP
Sbjct: 6    PVRFQEHFQLQNLGINPANIGFSTLTMESDKFICIREKVGEQAQVTIIDMSDPMAPIRRP 65

Query: 67   ITADSALMNPNSRILALKAQLQGTTQDHLQIFNIELKAKMKSYQMPEQVVFWKWISPKLL 126
            I+A+SA+MNP S+++ALKA   G T   LQIFNIE+K+KMK++ M E+V+FWKW+S   +
Sbjct: 66   ISAESAIMNPASKVIALKA---GKT---LQIFNIEMKSKMKAHTMAEEVIFWKWVSVNTV 119

Query: 127  GLVTQTSVYHWSIEGDSEPVKMFERTANLANNQIINYRCDPTEKWLVLIGIAPGSPERPQ 186
             LVT+T+VYHWS+EGDS+P+KMF+R  +L   Q+I+YR D  +KWL+L+GI+     +  
Sbjct: 120  ALVTETAVYHWSMEGDSQPMKMFDRHTSLVGCQVIHYRTDEYQKWLLLVGISA----QQN 175

Query: 187  LVKGNMQLFSVEQQRSQALEAHAASFAQFKVPGNENPSTLISFATKTVNAGQVISKLHVI 246
             V G MQL+SV+++ SQ +E HAA+FA+FK+ GN  P+TL  FA +    G    KLH+I
Sbjct: 176  RVVGAMQLYSVDRKVSQPIEGHAAAFAEFKMEGNAKPATLFCFAVRNPTGG----KLHII 231

Query: 247  ELGAQP--GKPSFTKKQADLFFPPDFADDFPVSMQISHKYSLIYVITKLGLLFVYDLETA 304
            E+G QP  G   F KK  D+FFPP+  +DFPV+MQI  K+ +IY+ITK G L +YDLE+ 
Sbjct: 232  EVG-QPAAGNQPFVKKAVDVFFPPEAQNDFPVAMQIGAKHGVIYLITKYGYLHLYDLESG 290

Query: 305  TAVYRNRISPDPIFLTSEATSVGGFYAINRRGQVLLATVNEQTIVNFVSGQLNNLELAVN 364
              +  NRIS D IF+T+      G   +N++GQVL   V E  IVN+ +  L N +L + 
Sbjct: 291  VCICMNRISADTIFVTAPHKPTSGIIGVNKKGQVLSVCVEEDNIVNYATNVLQNPDLGLR 350

Query: 365  LAKRGNLPGAEKLVVERFHELFAQTKYKEAAELAAESPQGILRTPDTVAKFQSVPVQAGQ 424
            LA R NL GAEKL V +F+ LFAQ  Y EAA++AA +P+GILRT +TV KFQS+P Q+GQ
Sbjct: 351  LAVRSNLAGAEKLFVRKFNTLFAQGSYAEAAKVAASAPKGILRTRETVQKFQSIPAQSGQ 410

Query: 425  TPPLLQYFGTLLTRGKLNAFESLELSRLVVNQNKKNLLENWLAEDKLECSEELGDLVKTV 484
              PLLQYFG LL +G+LN  ESLEL  LV+ Q +K LLE WL EDKLECSEELGDLVKT 
Sbjct: 411  ASPLLQYFGILLDQGQLNKLESLELCHLVLQQGRKQLLEKWLKEDKLECSEELGDLVKTT 470

Query: 485  DNDLALKIYIKARATPKVVAAFAEKREFDKILIYSKQVGYTPDYLFLLQSILRTDPQGAV 544
            D  LAL +Y++A    KV+  FAE  +F KI++Y+K+VGYTPD++FLL+ +++  P+  +
Sbjct: 471  DPMLALSVYLRANVPSKVIQCFAETGQFQKIVLYAKKVGYTPDWIFLLRGVMKISPEQGL 530

Query: 545  NFALMMSQMEGGCPVDYNTITDLFLQRNLIREATAFLLDVLKPNLPEHGFLQTKVLEINL 604
             F+ M+ Q E     + + I D+F++ +LI++ T+FLLD LK N P  G LQT +LE+NL
Sbjct: 531  QFSRMLVQDEEPL-ANISQIVDIFMENSLIQQCTSFLLDALKNNRPAEGLLQTWLLEMNL 589

Query: 605  VTFPNVADAILANGMFSHYDRPRIAQLCEKAGLYVRALQHYTELPDIKRVIVNTHAIEPQ 664
            V  P VADAIL N MF+HYDR  IAQLCEKAGL  +AL+HYT+L DIKR +V+TH + P+
Sbjct: 590  VHAPQVADAILGNKMFTHYDRAHIAQLCEKAGLLQQALEHYTDLYDIKRAVVHTHLLNPE 649

Query: 665  ALVEFFGTLSKEWALECMKDLLLVNLRGNLQIIVQVAKEYCEQLGVDACIKIFEQFRSYE 724
             LV FFG+LS E ++EC+  +L  N+R NLQ+ VQVA +Y EQLG  A +++FE F+SY+
Sbjct: 650  WLVNFFGSLSVEDSVECLHAMLSANIRQNLQLCVQVASKYHEQLGTQALVELFESFKSYK 709

Query: 725  GLYFFLGSYLSSSEDPDIHFKYIEAAAKTGQIKEVERVTRESSFYDPEKTKNFLMEAKLP 784
            GL++FLGS ++ S+DPD+H KYI+AA KTGQIKEVER+ RESS Y+PE+ KNFL EAKL 
Sbjct: 710  GLFYFLGSIVNFSQDPDVHLKYIQAACKTGQIKEVERICRESSCYNPERVKNFLKEAKLT 769

Query: 785  DARPLINVCDRFGFVPDLTHYLYTSNMLRYIEGYVQKVNPGNAPLVVGQLLDDECPEDFI 844
            D  PLI VCDRFGFV DL  YLY +N+ RYIE YVQKVNP   P V+G LLD +C E+ I
Sbjct: 770  DQLPLIIVCDRFGFVHDLVLYLYRNNLQRYIEIYVQKVNPSRTPAVIGGLLDVDCSEEVI 829

Query: 845  KGLILSVRSLLPVEPLVAECEKRNRLRLLTQFLEHLVSEGSQDVHVHNALGKIIIDSNNN 904
            K LI++VR     + LVAE EKRNRL+LL  +LE  + EG ++   HNAL KI IDSNN+
Sbjct: 830  KHLIMAVRGQFSTDELVAEVEKRNRLKLLLPWLESQIQEGCEEPATHNALAKIYIDSNNS 889

Query: 905  PEHFLTTNPYYDSRVVGKYCEKRDPTLAVVAYRRGVCDDELINVTNKNSLFKLQARYVVE 964
            PE FL  N YYDS VVG+YCEKRDP LA VAY RG CD ELI V N+NSLFK +ARY+V 
Sbjct: 890  PECFLRENAYYDSSVVGRYCEKRDPHLACVAYERGQCDLELIKVCNENSLFKSEARYLVC 949

Query: 965  RMDADLWEKVLNPDNTYRRQLIDQVVSTALPESKSPEQVSASVKAFMTADLPHELIELLE 1024
            R D +LW  VL   N  RRQLIDQVV TAL E++ PE++S +VKAFMTADLP+ELIELLE
Sbjct: 950  RKDPELWAHVLEETNPSRRQLIDQVVQTALSETRDPEEISVTVKAFMTADLPNELIELLE 1009

Query: 1025 KIVLQNSAFSGNFNLQNLLILTAIKADSSRVMDYVNRLDNFDGPQVGEVAVEAELYEEAF 1084
            KIVL NS FS + NLQNLLILTAIKAD +RVM+Y++RLDN+D   +  +AV + LYEEAF
Sbjct: 1010 KIVLDNSVFSEHRNLQNLLILTAIKADRTRVMEYISRLDNYDALDIASIAVSSALYEEAF 1069

Query: 1085 AIFKKFNLNVQAVNVLLDNIHSIDRAVEFAFRVEEDAVWSQVAKAQLREGLVSDAIESFI 1144
             +F KF++N  A+ VL+++I ++DRA EFA R  E AVWSQ+A+AQL++ LV +AI S+I
Sbjct: 1070 TVFHKFDMNASAIQVLIEHIGNLDRAYEFAERCNEPAVWSQLAQAQLQKDLVKEAINSYI 1129

Query: 1145 RADDATQFLDVIRAAQDGNAYQDLVRYLLMVRQKTKEPKVDSELIYAYAKIDRLSDIEEF 1204
            R DD + +L+V+++A   N ++DLV++L M R+K +E  +++ELI+A AK  R+S++E+F
Sbjct: 1130 RGDDPSSYLEVVQSASRSNNWEDLVKFLQMARKKGRESYIETELIFALAKTSRVSELEDF 1189

Query: 1205 ILMPNVANLQNVGDRLYDEELYEAAKIIFAFISNWAKLAVTLVKLKQFQGAVDAARKANS 1264
            I  PN A++Q VGDR Y+E +YEAAK++++ +SN+A+LA TLV L ++Q AVD +RKA+S
Sbjct: 1190 INGPNNAHIQQVGDRCYEEGMYEAAKLLYSNVSNFARLASTLVHLGEYQAAVDNSRKASS 1249

Query: 1265 AKTWKEVCFACVDEEEFRLAQICGLNIIIQVDDLEEVSEYYQNRGCFNELISLMESGLGL 1324
             +TWKEVCFAC+D +EFR AQ+CGL+I+I  D+LEE+  YYQ+RG F ELI L+E+ LGL
Sbjct: 1250 TRTWKEVCFACMDGQEFRFAQLCGLHIVIHADELEELMCYYQDRGYFEELILLLEAALGL 1309

Query: 1325 ERAHMGIFTELGVLYARYRPEKLMEHIKLFATRLNIPKLIRACDEQQHWKELTYLYIQYD 1384
            ERAHMG+FTEL +LY++++P+K++EH++LF +R+NIPK++RA ++   W EL +LY +Y+
Sbjct: 1310 ERAHMGMFTELAILYSKFKPQKMLEHLELFWSRVNIPKVLRAAEQAHLWAELVFLYDKYE 1369

Query: 1385 EFDNAATTIMNHSPEAWDHMQFKDVIAKVANVELYYKAVHFYLQEHPDLINDVLNVLALR 1444
            E+DNA  T+M+H  EAW   QFKD+I KVANVEL Y+A+ FYL   P LIND+L VL+ R
Sbjct: 1370 EYDNAVLTMMSHPTEAWKEGQFKDIITKVANVELCYRALQFYLDYKPLLINDLLLVLSPR 1429

Query: 1445 VDHARVVDIMRKAGHLRLVKPYMVAVQSNNVSAVNEALNEIYVEEEDYDRLRESIDLHDN 1504
            +DH   V    KAG L LVKPY+ +VQS+N  +VNEALN +  EEEDY  LR SID +DN
Sbjct: 1430 LDHTWTVSFFSKAGQLPLVKPYLRSVQSHNNKSVNEALNHLLTEEEDYQGLRASIDAYDN 1489

Query: 1505 FDQIGLAQKIEKHELLEMRRVAAYIYKKAGRWKQSIALSKKDNLYKDAMETASQSGEREL 1564
            FD I LAQ++EKH+L+E R +AAY+YK    W QS+ L KKD+LYKDAM+ A++S + EL
Sbjct: 1490 FDNISLAQQLEKHQLMEFRCIAAYLYKGNNWWAQSVELCKKDHLYKDAMQHAAESRDAEL 1549

Query: 1565 AEELLVYFIDQGKKECFASCLFVCYDLIRVDVALELAWMHNMIDFAFPYLLQFIREYTGK 1624
            A++LL +F+++GK+ECFA+CLF CYDL+R D+ LELAW HN++D A PY +Q +REY  K
Sbjct: 1550 AQKLLQWFLEEGKRECFAACLFTCYDLLRPDMVLELAWRHNLVDLAMPYFIQVMREYLSK 1609

Query: 1625 VDEL 1628
            VD+L
Sbjct: 1610 VDKL 1613


>CLH_DICDI (P25870) Clathrin heavy chain
          Length = 1694

 Score = 1809 bits (4686), Expect = 0.0
 Identities = 915/1709 (53%), Positives = 1236/1709 (71%), Gaps = 36/1709 (2%)

Query: 6    NAPILMREALTLPSIGINPQHITFTHVTMESDKYICVRETAP--QNSVVIVDMNMPNQPL 63
            N PI  +E L L ++GI    I F+ +TMES+KYIC+RET P  +N+VVI+D + P+Q L
Sbjct: 3    NLPIRFQEVLQLTNLGIGSNSIGFSTLTMESEKYICIRETTPDDKNNVVIIDTDNPSQIL 62

Query: 64   RRPITADSALMNPNSRILALKAQLQGTTQDHLQIFNIELKAKMKSYQMPEQVVFWKWISP 123
            R+ +  D+A+MNP   ILALK          LQ+ +IE K ++KS QM E + FWKWISP
Sbjct: 63   RKQMKTDAAIMNPKEPILALKIG------QVLQLISIEQKMQLKSCQMQEPLEFWKWISP 116

Query: 124  KLLGLVTQTSVYHWSIEGDSEPVKMFERTANLANNQIINYRCDPTEKWLVLIGIAPGSPE 183
              L LVT TSV+HW+ EG+S+PVK+F+R  +L N +IINYR D T+ WLVL+ I     +
Sbjct: 117  NTLALVTATSVFHWTKEGNSDPVKVFDRHPDLQNTEIINYRSDSTQNWLVLVAIH----Q 172

Query: 184  RPQLVKGNMQLFSVEQQRSQALEAHAASFAQFKVPGNENPSTLISFATKTVNAGQVISKL 243
            R   V G +QL+SVE+Q SQ++E HAA FA + VPG   PSTL + +++T NA    SK+
Sbjct: 173  RDGRVVGRIQLYSVEKQISQSIEGHAACFANYIVPGATRPSTLFAISSRTQNA----SKI 228

Query: 244  HVIELGAQPGKPSFTKKQADLFFPPDF-ADDFPVSMQISHKYSLIYVITKLGLLFVYDLE 302
             V+E+    G P+F K+ +D+F+PP+  A DFPV+MQ+S KY +IY++TKLG + ++DL 
Sbjct: 229  LVLEVSKGDG-PNFQKRASDVFYPPEIGASDFPVAMQVSEKYEVIYMVTKLGYIHLFDLG 287

Query: 303  TATAVYRNRISPDPIFLTSEATSVGGFYAINRRGQVLLATVNEQTIVNFVSGQLNNLELA 362
            TA  +YRNRIS + IF+T+   S  G  A+NR+GQVL  +++++ I+ ++   LNNLELA
Sbjct: 288  TANLIYRNRISNENIFVTAFEESTNGIIAVNRKGQVLSVSIDDKNIIPYICNTLNNLELA 347

Query: 363  VNLAKRGNLPGAEKLVVERFHELFAQTKYKEAAELAAESPQGILRTPDTVAKFQSVPVQA 422
            +++A + NLPGAE L+  +F   F Q +YKEAA++AA+SP  ILR   T+ KFQS+P   
Sbjct: 348  ISMACKNNLPGAEGLLTTQFERYFQQGQYKEAAKVAADSPGSILRNLQTIQKFQSIPPIP 407

Query: 423  GQTPPLLQYFGTLLTRGKLNAFESLELSRLVVNQNKKNLLENWLAEDKLECSEELGDLVK 482
             Q   LLQYFG LL +GKLN  ESLEL R V+ Q KK +LE WL EDKLECSE+LGD V+
Sbjct: 408  DQPSALLQYFGMLLEKGKLNKVESLELVRPVLAQGKKPILEKWLTEDKLECSEQLGDEVR 467

Query: 483  TVDNDLALKIYIKARATPKVVAAFAEKREFDKILIYSKQVGYTPDYLFLLQSILRTDPQG 542
              D  LAL IY +A A+ KV+  FAE  EFDKI+ Y K+  Y PD++FLLQ +   +P G
Sbjct: 468  PHDRKLALSIYYRANASDKVITLFAETGEFDKIIAYCKKFNYKPDFMFLLQRMANANPMG 527

Query: 543  AVNFALMMSQMEGGCPVDYNTITDLFLQRNLIREATAFLLDVLKPNLPEHGFLQTKVLEI 602
            A +FA+ + + EGG  +D N + +LF  RN+I+E + FL  +L  + P+   LQTK+LEI
Sbjct: 528  AADFAVKLVKEEGGPYIDANQVVELFSARNMIQETSNFLFAILDGDRPQDANLQTKLLEI 587

Query: 603  NLVTFPNVADAILANGMFSHYDRPRIAQLCEKAGLYVRALQHYTELPDIKRVIVNT-HAI 661
            NL+  P  ADAI+    F+HY+R RI  LCEKAGLY RAL+HYT+L DIKRV+ +  H +
Sbjct: 588  NLLHAPQNADAIMGGQKFTHYNRLRIGGLCEKAGLYQRALEHYTDLADIKRVLSHAGHMV 647

Query: 662  EPQALVEFFGTLSKEWALECMKDLLLVNLRGNLQIIVQVAKEYCEQLGVDACIKIFEQFR 721
              + LV +FG+L+ E  +ECM+D L  N R NLQ++V +A  Y +Q+  +A I +FE FR
Sbjct: 648  NQEFLVSYFGSLNPEDRMECMRDFLRTNPRQNLQLVVAIAVSYSDQITPEAIIAMFESFR 707

Query: 722  SYEGLYFFLGSYLSSSEDPDIHFKYIEAAAKTGQIKEVERVTRESSFYDPEKTKNFLMEA 781
             YEGLY +L   + +S  P++HFKYIEAAAK  Q KEVER+ R+S++YDPEKT++FL EA
Sbjct: 708  LYEGLYLYLTQVVVTSTSPEVHFKYIEAAAKINQFKEVERMCRDSNYYDPEKTRDFLKEA 767

Query: 782  KLPDARPLINVCDRFGFVPDLTHYLYTSNMLRYIEGYVQKVNPGNAPLVVGQLLDDECPE 841
            KLPD  PLI VCDR+ F+ DLT+YLY +N+ +YIE YVQK+NP N PLVVG LLD +C E
Sbjct: 768  KLPDQLPLIIVCDRYEFISDLTNYLYKNNLSKYIEAYVQKINPVNTPLVVGALLDLDCQE 827

Query: 842  DFIKGLILSVRSLLPVEPLVAECEKRNRLRLLTQFLEHLVSEGSQDVHVHNALGKIIIDS 901
            D+++ LI+SVR++ P + LV + EKRNRL+LL  +LE  V+EG+ +  +HNAL KI IDS
Sbjct: 828  DYLRNLIMSVRNMCPADSLVEQVEKRNRLKLLLPWLEARVAEGNIEPAIHNALAKIYIDS 887

Query: 902  NNNPEHFLTTNPYYDSRVVGKYCEKRDPTLAVVAYRRGVCDDELINVTNKNSLFKLQARY 961
            N NPE FL  N +YDS+VVGKYCEKRDP L+ VAY+RG+CD ELI VTNKN+LFK QARY
Sbjct: 888  NKNPEAFLLHNQFYDSKVVGKYCEKRDPYLSFVAYKRGLCDYELIEVTNKNTLFKNQARY 947

Query: 962  VVERMDADLWEKVLNPDNTYRRQLIDQVVSTALPESKSPEQVSASVKAFMTADLPHELIE 1021
            +VER D DLW  VL+  N Y+R LIDQVV TALPES +  +VSA+VKAFM A+LP+ELIE
Sbjct: 948  LVERQDPDLWAYVLSDQNEYKRSLIDQVVQTALPESTNATEVSATVKAFMDANLPNELIE 1007

Query: 1022 LLEKIVLQNSAFSGNFNLQNLLILTAIKADSSRVMDYVNRLDNFDGPQVGEVAVEAELYE 1081
            LLEKIVL+   F     LQNLLILTAI+AD SRV DY+NRLDNFDG ++  +A+E++LYE
Sbjct: 1008 LLEKIVLEGKEFKTAKELQNLLILTAIRADKSRVTDYINRLDNFDGSKLAPIAIESQLYE 1067

Query: 1082 EAFAIFKKFNLNVQAVNVLLDNIHSIDRAVEFAFRVEEDAVWSQVAKAQLREGLVSDAIE 1141
            EAF ++KKF  NV+A++VL+ +I SI+RA +FA R  +  V+S++  AQL+  +V + IE
Sbjct: 1068 EAFFMYKKFQFNVEAIDVLITHIGSIERAHDFAERCNQTEVYSKLGVAQLKAEMVKECIE 1127

Query: 1142 SFIRADDATQFLDVIRAAQDGNAYQDLVRYLLMVRQKTKEPKVDSELIYAYAKIDRLSDI 1201
            SFI+A+D   + +V+ AA+  + Y+DLV++L M R+K KEP ++SELI+AYAK+++L+++
Sbjct: 1128 SFIKANDTEHYQEVVAAAERKDEYEDLVKFLQMCRKKIKEPAIESELIFAYAKVNKLAEM 1187

Query: 1202 EEFILMPNVANLQNVGDRLYDEELYEAAKIIFAFISNWAKLAVTLVKLKQFQGAVDAARK 1261
            E+FI  PN A++Q VGDR ++  LYEAAK+++  ISN+++L   LVKL Q+Q AVDAARK
Sbjct: 1188 EDFINSPNSAHIQVVGDRCFENGLYEAAKVLYTNISNFSRLTSCLVKLGQYQAAVDAARK 1247

Query: 1262 ANSAKTWKEVCFACVDEEEFRLAQICGLNIIIQVDDLEEVSEYYQNRGCFNELISLMESG 1321
            ANS KTWKEV  AC+D +EFRLAQ+CG+NII+  D+LEE+   Y++RG FNELISL+ESG
Sbjct: 1248 ANSTKTWKEVSAACIDAKEFRLAQVCGINIIVHGDELEELIRQYEDRGYFNELISLLESG 1307

Query: 1322 LGLERAHMGIFTELGVLYARYRPEKLMEHIKLFATRLNIPKLIRACDEQQHWKELTYLYI 1381
            L  ERAH+G+FTEL +LY++Y+ EKLMEH+KLF +RLN+PK+I+AC   Q W +LTYLYI
Sbjct: 1308 LASERAHVGMFTELAILYSKYKEEKLMEHLKLFYSRLNVPKVIKACQANQQWPQLTYLYI 1367

Query: 1382 QYDEFDNAATTIMNHSPEAWDHMQFKDVIAKVANVELYYKAVHFYLQEHPDLINDVLNVL 1441
             YDE DNA  T++NHS EAWDH+ FK+ I KVA ++LYY A+ FYL+E P LIND+L+VL
Sbjct: 1368 HYDEHDNAIQTMINHSIEAWDHVLFKETIPKVAKLDLYYSAISFYLEEQPLLINDLLSVL 1427

Query: 1442 ALRVDHARVVDIMRKAGHLRLVKPYMVAVQSNNVSAVNEALNEIYVEEEDYDRLRESIDL 1501
            + R+DH R V ++R  GHL LVKPY+V+ Q  NV+A+NEALNE+YVEEEDY+ LR SID 
Sbjct: 1428 SPRIDHTRAVTLIRSLGHLPLVKPYLVSAQDQNVAALNEALNELYVEEEDYESLRSSIDA 1487

Query: 1502 HDNFDQIGLAQKIEKHELLEMRRVAAYIYKKAGRWKQSIALSKKDNLYKDAMETASQSGE 1561
            + NF  I LAQK+EKHELLE RR+AAY+YKK  RW QS+ LSKKD LYKDA+++AS S  
Sbjct: 1488 NSNFGTIALAQKLEKHELLEFRRIAAYLYKKNNRWAQSVELSKKDKLYKDAIQSASDSKN 1547

Query: 1562 RELAEELLVYFIDQGKKECFASCLFVCYDLIRVDVALELAWMHNMIDFAFPYLLQFIREY 1621
              + EELL YF+DQ     FA+CL+ CYD ++ D  +ELAW +N+++++FPYL+Q+++EY
Sbjct: 1548 PAIGEELLQYFVDQQNNSAFAACLYTCYDFLKPDAVIELAWRNNILNYSFPYLIQYVKEY 1607

Query: 1622 TGKVDELVKHKIESQNEVKAKEQEEKEVIAQQNMYAQLLPLALPAPPMPGMGGG---MGG 1678
            T KVD+LV       ++ KA++++ +E   QQN+ +         P +  +  G    GG
Sbjct: 1608 TTKVDQLV-------DDFKARQKKTEEEKEQQNIESSQY-----QPDLTNLSYGYAATGG 1655

Query: 1679 GYAPPPPMGGGMGMPPMPPF--GMPMGGY 1705
              A PP +G      P   +     MGG+
Sbjct: 1656 MLALPPAVGYQQQQQPQQMYNPNQMMGGF 1684


>CLH_CAEEL (P34574) Probable clathrin heavy chain
          Length = 1681

 Score = 1801 bits (4666), Expect = 0.0
 Identities = 914/1693 (53%), Positives = 1231/1693 (71%), Gaps = 25/1693 (1%)

Query: 8    PILMREALTLPSIGINPQHITFTHVTMESDKYICVRET-APQNSVVIVDMNMPNQPLRRP 66
            PI   E L LP+ GI   +ITF++VTMESDK I VRE    Q  VVI+D+     P RRP
Sbjct: 4    PIKFHEHLQLPNAGIRVPNITFSNVTMESDKNIVVREMIGDQQQVVIIDLADTANPTRRP 63

Query: 67   ITADSALMNPNSRILALKAQLQGTTQDHLQIFNIELKAKMKSYQMPEQVVFWKWISPKLL 126
            I+ADS +M+P ++ILALK+   G T   LQIFNIELKAK+K++Q  E VV+WKWIS K +
Sbjct: 64   ISADSVIMHPTAKILALKS---GKT---LQIFNIELKAKVKAHQNVEDVVYWKWISEKTI 117

Query: 127  GLVTQTSVYHWSIEGDSEPVKMFERTANLANNQIINYRCDPTEKWLVLIGIAPGSPERPQ 186
             LV+ T+VYHWSIEGD+ PVKMF+R  +LA  QIINYR D   KWLVLIGI+     +  
Sbjct: 118  ALVSDTAVYHWSIEGDAAPVKMFDRHQSLAGTQIINYRADAENKWLVLIGISA----KDS 173

Query: 187  LVKGNMQLFSVEQQRSQALEAHAASFAQFKVPGNENPSTLISFATKTVNAGQVISKLHVI 246
             V G+MQL+S E++ SQ +E HAA F +FKV GN+NPS L  F+ KT N G    KLHVI
Sbjct: 174  RVVGSMQLYSTERKVSQPIEGHAACFVRFKVDGNQNPSNLFCFSVKTDNGG----KLHVI 229

Query: 247  ELGAQP-GKPSFTKKQADLFFPPDFADDFPVSMQISHKYSLIYVITKLGLLFVYDLETAT 305
            E+G    G   F KK  D+ +  D A DFPVSMQ+S K  +IY++TK G + +YD+E+ T
Sbjct: 230  EVGTPAAGNTPFQKKNVDVPYTADTAGDFPVSMQVSAKQGIIYLVTKQGYVHLYDVESGT 289

Query: 306  AVYRNRISPDPIFLTSEATSVGGFYAINRRGQVLLATVNEQTIVNFVSGQLNNLELAVNL 365
             +Y NRIS D +F+T E T+ GG   INR+GQVL  +++E  +V FV+ QL N +LA+ L
Sbjct: 290  RIYSNRISTDTVFVTCEYTATGGIMGINRKGQVLSVSIDEANLVPFVTNQLQNPDLALKL 349

Query: 366  AKRGNLPGAEKLVVERFHELFAQTKYKEAAELAAESPQGILRTPDTVAKFQSVPVQAGQT 425
            A R +LPGAE+L V +F+ LF+  ++ E+A++AA +PQGILRTP T+ KFQ  P      
Sbjct: 350  AVRCDLPGAEELFVRKFNLLFSNGQFGESAKVAASAPQGILRTPATIQKFQQCPSTGPGP 409

Query: 426  PPLLQYFGTLLTRGKLNAFESLELSRLVVNQNKKNLLENWLAEDKLECSEELGDLVKTVD 485
             PLLQYFG LL +GKLN +E+LEL R V+ Q +K L+  WL + KLEC EELGDL+K  D
Sbjct: 410  SPLLQYFGILLDQGKLNKYETLELCRPVLAQGRKELITKWLNDQKLECCEELGDLIKPHD 469

Query: 486  NDLALKIYIKARATPKVVAAFAEKREFDKILIYSKQVGYTPDYLFLLQSILR-TDPQGAV 544
             + AL +Y++     KVV +FAE  +FDKI++Y+K+VG+ PDYLF L+ ILR ++P    
Sbjct: 470  VNTALSVYLRGNVPHKVVQSFAETGQFDKIVMYAKRVGFQPDYLFQLRQILRNSNPDHGA 529

Query: 545  NFA-LMMSQMEGGCPV-DYNTITDLFLQRNLIREATAFLLDVLKPNLPEHGFLQTKVLEI 602
             FA L++S+ E G P+ D + I D F++   ++  T+FLL+VLK + PE G LQT++LE+
Sbjct: 530  KFAQLLVSESENGEPLADLSQIIDCFMEVQAVQPCTSFLLEVLKGDKPEEGHLQTRLLEM 589

Query: 603  NLVTFPNVADAILANGMFSHYDRPRIAQLCEKAGLYVRALQHYTELPDIKRVIVNTHAIE 662
            NL+  P VADAILAN MFSHYDR  I QLCEKAGL  RAL+H+T+L DIKR +V+TH ++
Sbjct: 590  NLLAAPAVADAILANKMFSHYDRAAIGQLCEKAGLLQRALEHFTDLYDIKRTVVHTHLLK 649

Query: 663  PQALVEFFGTLSKEWALECMKDLLLVNLRGNLQIIVQVAKEYCEQLGVDACIKIFEQFRS 722
            P  LV +FG+LS E ++EC+K +L  N+R NLQ++VQ+A +Y EQLG D  I++FE  +S
Sbjct: 650  PDWLVGYFGSLSVEDSVECLKAMLTQNIRQNLQVVVQIASKYHEQLGADKLIEMFENHKS 709

Query: 723  YEGLYFFLGSYLSSSEDPDIHFKYIEAAAKTGQIKEVERVTRESSFYDPEKTKNFLMEAK 782
            YEGL++FLGS ++ S+DP++HFKYI+AA +TGQIKEVER+ RES  YD E+ KNFL EAK
Sbjct: 710  YEGLFYFLGSIVNFSQDPEVHFKYIQAATRTGQIKEVERICRESQCYDAERVKNFLKEAK 769

Query: 783  LPDARPLINVCDRFGFVPDLTHYLYTSNMLRYIEGYVQKVNPGNAPLVVGQLLDDECPED 842
            L D  PLI VCDR   V DL  YLY + + +YIE +VQKVN    P+VVG LLD +C ED
Sbjct: 770  LNDQLPLIIVCDRHNMVHDLVLYLYRNQLQKYIEVFVQKVNAARLPIVVGALLDVDCSED 829

Query: 843  FIKGLILSVRSLLPVEPLVAECEKRNRLRLLTQFLEHLVSEGSQDVHVHNALGKIIIDSN 902
             IK LI++ R    ++ LV E EKRNRL+LL  +LE  + EG+ D   HNA+ KI IDSN
Sbjct: 830  AIKQLIINTRGKFDIDELVEEVEKRNRLKLLNHWLESKIQEGATDAATHNAMAKIYIDSN 889

Query: 903  NNPEHFLTTNPYYDSRVVGKYCEKRDPTLAVVAYRRGVCDDELINVTNKNSLFKLQARYV 962
            NNPE FL  NPYYDS+VVGKYCEKRDP  A ++Y RG CD ELINV N+NSLFK  ARY+
Sbjct: 890  NNPERFLKENPYYDSKVVGKYCEKRDPHYAFLSYERGQCDAELINVCNENSLFKNLARYL 949

Query: 963  VERMDADLWEKVLNPDNTYRRQLIDQVVSTALPESKSPEQVSASVKAFMTADLPHELIEL 1022
            V+R D  LWE+VLN +N +RRQLIDQVV TAL E++ PE +S +VKAFM ADLP+ELIEL
Sbjct: 950  VKRRDFTLWEQVLNEENVHRRQLIDQVVQTALSETQDPEDISVTVKAFMAADLPNELIEL 1009

Query: 1023 LEKIVLQNSAFSGNFNLQNLLILTAIKADSSRVMDYVNRLDNFDGPQVGEVAVEAELYEE 1082
            LEKIVL NSAFS + NLQNLLILTA++AD +RVM+Y+ +LDN+D P +  +A+ +ELYEE
Sbjct: 1010 LEKIVLDNSAFSEHRNLQNLLILTAMRADRTRVMEYIQKLDNYDAPDIANIAITSELYEE 1069

Query: 1083 AFAIFKKFNLNVQAVNVLLDNIHSIDRAVEFAFRVEEDAVWSQVAKAQLREGLVSDAIES 1142
            AFAIFKKF++N  A+NVL++N++++DRA EFA +  +  VW+ +AKAQL++ LV +A++S
Sbjct: 1070 AFAIFKKFDVNSSAINVLIENVNNLDRAYEFAEKCNQSDVWASLAKAQLQQNLVKEAVDS 1129

Query: 1143 FIRADDATQFLDVIRAAQDGNAYQDLVRYLLMVRQKTKEPKVDSELIYAYAKIDRLSDIE 1202
            FI+ADD   +++V+        ++DLVRYL M R+K++E  +++EL++A AK  RL+++E
Sbjct: 1130 FIKADDPGAYMEVVNKCSQTEHWEDLVRYLQMARKKSRESYIETELVFALAKTGRLTELE 1189

Query: 1203 EFILMPNVANLQNVGDRLYDEELYEAAKIIFAFISNWAKLAVTLVKLKQFQGAVDAARKA 1262
            EFI  PN A +  +GDR +D  ++++AKI+F  +SN+AKL+VTLV+L ++QGAVDAARKA
Sbjct: 1190 EFIAGPNHAQIGQIGDRCFDNGMFDSAKILFNNVSNFAKLSVTLVRLGEYQGAVDAARKA 1249

Query: 1263 NSAKTWKEVCFACVDEEEFRLAQICGLNIIIQVDDLEEVSEYYQNRGCFNELISLMESGL 1322
            NS KTWK+VCF+CV+  EFRLAQ+CGL+I++  D+LEE+  +YQ+RG F ELI+L+E+ L
Sbjct: 1250 NSTKTWKQVCFSCVENGEFRLAQMCGLHIVVHADELEELINFYQDRGHFEELIALLEAAL 1309

Query: 1323 GLERAHMGIFTELGVLYARYRPEKLMEHIKLFATRLNIPKLIRACDEQQHWKELTYLYIQ 1382
            GLERAHMG+FTEL +LY++Y+PEK+ EH++LF +R+NIPK++RA ++   W EL +LY +
Sbjct: 1310 GLERAHMGMFTELAILYSKYKPEKMREHLELFWSRVNIPKVLRAAEQAHLWSELVFLYDK 1369

Query: 1383 YDEFDNAATTIMNHSPEAWDHMQFKDVIAKVANVELYYKAVHFYLQEHPDLINDVLNVLA 1442
            Y+E+DNAA T+M H  E+W    FK+VIAKVANVELYYKA+ FYL   P L+ND+L VL+
Sbjct: 1370 YEEYDNAALTMMQHPTESWREQHFKEVIAKVANVELYYKAMQFYLDYKPLLLNDLLTVLS 1429

Query: 1443 LRVDHARVVDIMRKAGHLRLVKPYMVAVQSNNVSAVNEALNEIYVEEEDYDRLRESIDLH 1502
             R+DH+R V    K   + LVKPY+  VQ+ N  A+NEALN++ ++EED+  LR SI+  
Sbjct: 1430 PRLDHSRTVLFFNKLKQIPLVKPYLRQVQNLNNKAINEALNQLLIDEEDHAGLRSSIEAQ 1489

Query: 1503 DNFDQIGLAQKIEKHELLEMRRVAAYIYKKAGRWKQSIALSKKDNLYKDAMETASQSGER 1562
            DNFD I LAQ++EKH L+E RR++AY++K   RWKQSI L KKD LYKDAME A++S   
Sbjct: 1490 DNFDNITLAQQLEKHPLVEFRRISAYLFKGNNRWKQSIELCKKDKLYKDAMEYAAESRNG 1549

Query: 1563 ELAEELLVYFIDQGKKECFASCLFVCYDLIRVDVALELAWMHNMIDFAFPYLLQFIREYT 1622
            ELAEELL +F+D+   +CFA+ L+ CYDL+  DV +ELAW H ++D+A PY++Q +R+Y 
Sbjct: 1550 ELAEELLSFFLDEKLYDCFAASLYHCYDLLHPDVIMELAWKHKIMDYAMPYMIQVMRDYQ 1609

Query: 1623 GKVDELVKHKIESQNEVKAKEQEEKEVIAQQNMYAQLLPLALPAPPM--PGMGGGMGGGY 1680
             ++++L + + E + E KA++Q+   +  +  +   +L    PAP M  PG  GG GG  
Sbjct: 1610 TRLEKLERSEHERKEE-KAEQQQNNGMTMEPQL---MLTYGAPAPQMTYPGTTGGYGGQP 1665

Query: 1681 APPPPMGGGMGMP 1693
            A   P   G   P
Sbjct: 1666 AYGQPGQPGYNAP 1678


>CLH_SCHPO (Q10161) Probable clathrin heavy chain
          Length = 1666

 Score = 1618 bits (4190), Expect = 0.0
 Identities = 808/1647 (49%), Positives = 1150/1647 (69%), Gaps = 21/1647 (1%)

Query: 4    AANAPILMREALTLPSIGINPQHITFTHVTMESDKYICVRETAPQ-NSVVIVDMNMPNQP 62
            A   PI   E L L S+GI P    F +VT+ESDKY+CVR+     N VVIVD+  P+  
Sbjct: 2    AQQLPIRFSEVLQLASVGIQPSSFGFANVTLESDKYVCVRDNPNGVNQVVIVDLEDPSNV 61

Query: 63   LRRPITADSALMNPNSRILALKAQLQGTTQDHLQIFNIELKAKMKSYQMPEQVVFWKWIS 122
            LRRPI+ADS +++P  +I+ALKAQ Q      LQ+F++E KAK+ SY M + VV+W WIS
Sbjct: 62   LRRPISADSVILHPKKKIIALKAQRQ------LQVFDLEAKAKINSYVMNQDVVYWTWIS 115

Query: 123  PKLLGLVTQTSVYHWSIEGDSEPVKMFERTANLANNQIINYRCDPTEKWLVLIGIAPGSP 182
              ++G+VT TSV+HW++ G S+PVKMF+R ++L   QII+Y+ +  E+W  LIGI+    
Sbjct: 116  DSVIGMVTDTSVFHWTVSG-SDPVKMFDRHSSLNGTQIISYKSNYNEEWFTLIGIS---- 170

Query: 183  ERPQLVKGNMQLFSVEQQRSQALEAHAASFAQFKVPGNENPSTLISFATKTVNAGQVISK 242
             R   + GN+QL+S +++ SQ LE+HA++FA  +  G ++   +++ A++        SK
Sbjct: 171  SRDNRIAGNLQLYSKKRKVSQPLESHASAFAVIQPEGVDHEVQVLALASRLPTG----SK 226

Query: 243  LHVIELGAQPGKPSFTKKQADLFFPPDFADDFPVSMQISHKYSLIYVITKLGLLFVYDLE 302
            L ++E+   P  P+F  K  DLFFPP+  +DFP++++I   Y++ YV+TK G + VYDLE
Sbjct: 227  LSIVEVDRNPNNPAFATKTVDLFFPPEAVNDFPIAIEIGSTYNVAYVVTKYGFIHVYDLE 286

Query: 303  TATAVYRNRISPDPIFLTSEATSVGGFYAINRRGQVLLATVNEQTIVNFVSGQLNNLELA 362
            TA  +Y NR+S + IF+T+   SV G  AINR+GQVL  ++N +TI+ ++   LN+  LA
Sbjct: 287  TAKCIYMNRVSGESIFVTTAHKSVNGLMAINRKGQVLSVSINPETIIPYILSNLNDPGLA 346

Query: 363  VNLAKRGNLPGAEKLVVERFHELFAQTKYKEAAELAAESPQGILRTPDTVAKFQSVPVQA 422
            V +A   NLPGA+ L +++F +L AQ  Y EAA++AA SP+GILRT   + +F+ +    
Sbjct: 347  VRMASHANLPGADNLYMQQFQQLMAQGNYSEAAKVAASSPRGILRTSQVIDQFKLIQAAP 406

Query: 423  GQTPPLLQYFGTLLTRGKLNAFESLELSRLVVNQNKKNLLENWLAEDKLECSEELGDLVK 482
            GQ  P+LQYFGTLL +G LN  E++EL+R V+ QN+  LLE W  E+KL C+E LGDLVK
Sbjct: 407  GQIAPILQYFGTLLDKGPLNEHETIELARPVLAQNRIQLLEKWYGENKLACTEALGDLVK 466

Query: 483  TVDNDLALKIYIKARATPKVVAAFAEKREFDKILIYSKQVGYTPDYLFLLQSILRTDPQG 542
              +   ALKIY  A    KVV   +E  +F K+  Y+ Q   TPDY+ LLQ+++R +P  
Sbjct: 467  PYNTPFALKIYETANVPNKVVMCLSELGDFGKLATYTSQQNITPDYVSLLQNLVRVNPDQ 526

Query: 543  AVNFALMMSQMEGGCPVDYNTITDLFLQRNLIREATAFLLDVLKPNLPEHGFLQTKVLEI 602
            A  FA  M        ++   I D+F+ +NL+++ATAFLLD LK + PEH  LQT++LEI
Sbjct: 527  AAEFATQM--FNSNPSINLEKIVDIFMSQNLVQQATAFLLDALKDDNPEHSHLQTRLLEI 584

Query: 603  NLVTFPNVADAILANGMFSHYDRPRIAQLCEKAGLYVRALQHYTELPDIKRVIVNTHAIE 662
            NL+  P VADAIL N MF+H+DR  IA LCE+AGL  RAL+ Y +  DIKRVIV+++ + 
Sbjct: 585  NLINAPQVADAILGNQMFTHFDRAVIASLCERAGLVQRALELYDKPADIKRVIVHSNLLN 644

Query: 663  PQALVEFFGTLSKEWALECMKDLLLVNLRGNLQIIVQVAKEYCEQLGVDACIKIFEQFRS 722
            P+ L+ +F   S +   + ++++L  NLR NLQI+VQ+A  Y + +G    I++FE+F++
Sbjct: 645  PEWLMNYFSRFSPDEVYDYLREMLRSNLRQNLQIVVQIATRYSDLVGAQRIIEMFEKFKT 704

Query: 723  YEGLYFFLGSYLSSSEDPDIHFKYIEAAAKTGQIKEVERVTRESSFYDPEKTKNFLMEAK 782
            +EGLY++LGS ++ +EDP++ +KYI+AA    Q  EVER+ R+++ Y+PEK KN L EAK
Sbjct: 705  FEGLYYYLGSIVNITEDPEVVYKYIQAACLMNQFTEVERICRDNNVYNPEKVKNLLKEAK 764

Query: 783  LPDARPLINVCDRFGFVPDLTHYLYTSNMLRYIEGYVQKVNPGNAPLVVGQLLDDECPED 842
            L D  PLI VCDR+ FV DL  YL+ +NM ++IE YVQ++NP   P VVG LLD +C E+
Sbjct: 765  LADQLPLILVCDRYDFVNDLVFYLFRNNMFQFIEIYVQRINPSKTPQVVGALLDIDCDEE 824

Query: 843  FIKGLILSVRSLLPVEPLVAECEKRNRLRLLTQFLEHLVSEGSQDVHVHNALGKIIIDSN 902
             ++ L++SV   +PV+ LV E E+RNRL+LL  +LE L+  GSQD  +++AL KI IDSN
Sbjct: 825  LVQNLLMSVVGQVPVDELVEEVERRNRLKLLLPYLESLLQSGSQDRAIYDALAKIYIDSN 884

Query: 903  NNPEHFLTTNPYYDSRVVGKYCEKRDPTLAVVAYRRGVCDDELINVTNKNSLFKLQARYV 962
            NNPE FL  N +YD+  VGKYCEKRDP LA +AY +G  D E+IN+ N+NS+FK  ARY+
Sbjct: 885  NNPEVFLKENNFYDTLTVGKYCEKRDPYLAFIAYEKGGNDTEIINLCNENSMFKQLARYL 944

Query: 963  VERMDADLWEKVLNPDNTYRRQLIDQVVSTALPESKSPEQVSASVKAFMTADLPHELIEL 1022
            ++R D++LW +VL  D+ YRR L+DQV++TA+PES  PE VS  VKA M  DLP +LIEL
Sbjct: 945  LKRSDSNLWSEVLQ-DSAYRRPLLDQVIATAVPESSDPEAVSIVVKALMEVDLPSQLIEL 1003

Query: 1023 LEKIVLQNSAFSGNFNLQNLLILTAIKADSSRVMDYVNRLDNFDGPQVGEVAVEAELYEE 1082
            LEKIVLQ S+FS N NLQNLL LTAIKAD SRVM+Y+++LD +D  ++ E+A+E  LYEE
Sbjct: 1004 LEKIVLQPSSFSENANLQNLLFLTAIKADKSRVMEYIDKLDKYDVDEIAEIAIENGLYEE 1063

Query: 1083 AFAIFKKFNLNVQAVNVLLDNIHSIDRAVEFAFRVEEDAVWSQVAKAQLREGLVSDAIES 1142
            AF I+K  N + QA+ VL+++I S+DRA ++A  VE+  VWS++AKAQL    + DAIES
Sbjct: 1064 AFRIYKIHNKHEQAMKVLVEDIVSLDRAQDYAETVEQPEVWSRLAKAQLDGIRIPDAIES 1123

Query: 1143 FIRADDATQFLDVIRAAQDGNAYQDLVRYLLMVRQKTKEPKVDSELIYAYAKIDRLSDIE 1202
            +++ADD + + +VI  A     Y++L++YLLM R K  EP VDS L+ AYAK ++L+++E
Sbjct: 1124 YLKADDPSNYSEVIELASRAGKYEELIKYLLMARSKMHEPDVDSALLIAYAKTNQLTEME 1183

Query: 1203 EFILMPNVANLQNVGDRLYDEELYEAAKIIFAFISNWAKLAVTLVKLKQFQGAVDAARKA 1262
             F++  NVA+++ VGD  ++ + YEAAK++++ ISNW+ LA TLV L ++QGAVD ARKA
Sbjct: 1184 TFLIGSNVADVKAVGDECFESKNYEAAKLMYSSISNWSMLATTLVYLGEYQGAVDCARKA 1243

Query: 1263 NSAKTWKEVCFACVDEEEFRLAQICGLNIIIQVDDLEEVSEYYQNRGCFNELISLMESGL 1322
            NS K WK+V  AC+D+ EFRLAQICGLN+I+  ++L  +   Y+ RG F E+ISLME+GL
Sbjct: 1244 NSIKVWKQVGTACIDKREFRLAQICGLNLIVHAEELPGLIRLYEERGYFEEVISLMEAGL 1303

Query: 1323 GLERAHMGIFTELGVLYARYRPEKLMEHIKLFATRLNIPKLIRACDEQQHWKELTYLYIQ 1382
            GLERAHM  +TEL +LYA+Y+PE++MEH+KLF  RLN+ K+IRACD+   W E  +LY+ 
Sbjct: 1304 GLERAHMAFYTELAILYAKYKPERMMEHLKLFWGRLNMAKVIRACDQMHLWNEAVFLYVH 1363

Query: 1383 YDEFDNAATTIMNHSPEAWDHMQFKDVIAKVANVELYYKAVHFYLQEHPDLINDVLNVLA 1442
               +DNAA  +M   PEA+DH  FKD+I  VAN+ELYY+A++FYL++HP L+ D+L  L 
Sbjct: 1364 DQSYDNAA-AVMMEQPEAFDHQSFKDIIVHVANLELYYRALNFYLEQHPMLLTDLLAALT 1422

Query: 1443 LRVDHARVVDIMRKAGHLRLVKPYMVAVQSNNVSAVNEALNEIYVEEEDYDRLRESIDLH 1502
             R+DH RV+ I  K+ +  L+  +MVA+Q  N+ AVN A N++ +E EDY  L++SI+ +
Sbjct: 1423 PRIDHPRVIRIFEKSENTPLILNFMVAIQHLNIQAVNHAYNDLLIEMEDYQSLQDSIENY 1482

Query: 1503 DNFDQIGLAQKIEKHELLEMRRVAAYIYKKAGRWKQSIALSKKDNLYKDAMETASQSGER 1562
            D+FD I LA+++EKH LLE RR+AAYIY+K  RW QSI LSK+D  YKDA+ TA  S + 
Sbjct: 1483 DHFDAIALARRLEKHSLLEFRRIAAYIYRKNKRWTQSIELSKQDRFYKDAIITARDSDQT 1542

Query: 1563 ELAEELLVYFIDQGKKECFASCLFVCYDLIRVDVALELAWMHNMIDFAFPYLLQFIREYT 1622
             +AE+L+ YF++ G  ECFA+ L+ CY L+R D+ +E++W   + D+A+PY + F  E  
Sbjct: 1543 TIAEDLMKYFVEIGNYECFAAILYTCYHLLRNDLVMEISWRKGLQDYAYPYFINFQCEMF 1602

Query: 1623 GKVDELVKHKIESQNEVKAKEQEEKEV 1649
             KV  L K  ++ +  VK++E+    +
Sbjct: 1603 SKVLNLEK-DLKDRQAVKSEEESASTI 1628


>CLH_YEAST (P22137) Clathrin heavy chain
          Length = 1653

 Score = 1453 bits (3761), Expect = 0.0
 Identities = 725/1632 (44%), Positives = 1103/1632 (67%), Gaps = 18/1632 (1%)

Query: 5    ANAPILMREALTLPSIGINPQHITFTHVTMESDKYICVRETAP-QNSVVIVDMNMPNQPL 63
            ++ PI   E + L S+GI+PQ + F   T ESD ++ VRET    NSV IVD+   N+  
Sbjct: 2    SDLPIEFTELVDLMSLGISPQFLDFRSTTFESDHFVTVRETKDGTNSVAIVDLAKGNEVT 61

Query: 64   RRPITADSALMNPNSRILALKAQLQGTTQDHLQIFNIELKAKMKSYQMPEQVVFWKWISP 123
            R+ +  DSA+M+P+  +++++A   GT    +QIFN+E K+K+KS+ + E V+FW+W+S 
Sbjct: 62   RKNMGGDSAIMHPSQMVISVRAN--GTI---VQIFNLETKSKLKSFTLDEPVIFWRWLSE 116

Query: 124  KLLGLVTQTSVYHWSI---EGDSEPVKMFERTANLANNQIINYRCDPTEKWLVLIGIAPG 180
              LG VT  S+   ++     +++P  +  R ANL N QIIN+  +    W  ++GI   
Sbjct: 117  TTLGFVTARSILTSNVFDGNVNAKPQLLTLRHANLNNTQIINFVANKNLDWFAVVGILQE 176

Query: 181  SPERPQLVKGNMQLFSVEQQRSQALEAHAASFAQFKVPGNENPSTLISFATKTVNAGQVI 240
            +      + G +QLFS ++  SQA++ H A F    + GN +    + F T   NA    
Sbjct: 177  NGR----IAGRIQLFSKQRNISQAIDGHVAIFTNILLEGNGSTPVQV-FVTGNRNATTGA 231

Query: 241  SKLHVIELGAQPGKPS-FTKKQADLFFPPDFADDFPVSMQISHKYSLIYVITKLGLLFVY 299
             +L +IE+      PS + K+  D+FFPPD  +DFP+++Q+S KY +IY++TK G + +Y
Sbjct: 232  GELRIIEIDHDASLPSQYQKETTDIFFPPDATNDFPIAVQVSEKYGIIYLLTKYGFIHLY 291

Query: 300  DLETATAVYRNRISPDPIFLTSEATSVGGFYAINRRGQVLLATVNEQTIVNFVSGQLNNL 359
            +LET T ++ NRI+ + +F  +      G   IN++GQVL   ++   IV ++  +L+N+
Sbjct: 292  ELETGTNLFVNRITAESVFTAAPYNHENGIACINKKGQVLAVEISTSQIVPYILNKLSNV 351

Query: 360  ELAVNLAKRGNLPGAEKLVVERFHELFAQTKYKEAAELAAESPQGILRTPDTVAKFQSVP 419
             LA+ +A RG LPGA+ L  ++F  L  Q  Y+ AA++AA S    LR  +T+ + +++ 
Sbjct: 352  ALALIVATRGGLPGADDLFQKQFESLLLQNDYQNAAKVAASSTS--LRNQNTINRLKNIQ 409

Query: 420  VQAGQTPPLLQYFGTLLTRGKLNAFESLELSRLVVNQNKKNLLENWLAEDKLECSEELGD 479
               G   P+L YF TLL +GKLN  E++EL+R V+ Q++K L E WL EDKLECSEELGD
Sbjct: 410  APPGAISPILLYFSTLLDKGKLNKEETIELARPVLQQDRKQLFEKWLKEDKLECSEELGD 469

Query: 480  LVKTVDNDLALKIYIKARATPKVVAAFAEKREFDKILIYSKQVGYTPDYLFLLQSILRTD 539
            +VK  D  LAL  Y++A A  KV++  AE ++F+KI+ Y ++VGY P++L L+ S++R+ 
Sbjct: 470  IVKPFDTTLALACYLRAGAHAKVISCLAELQQFEKIIPYCQKVGYQPNFLVLISSLIRSS 529

Query: 540  PQGAVNFALMMSQM-EGGCPVDYNTITDLFLQRNLIREATAFLLDVLKPNLPEHGFLQTK 598
            P  A  FA+ + Q  E    +D   I DLF  +N I++ T+ LLD LK + P+ G LQT+
Sbjct: 530  PDRASEFAVSLLQNPETASQIDIEKIADLFFSQNHIQQGTSLLLDALKGDTPDQGHLQTR 589

Query: 599  VLEINLVTFPNVADAILANGMFSHYDRPRIAQLCEKAGLYVRALQHYTELPDIKRVIVNT 658
            VLE+NL+  P VADAIL N +FSHYD+P IA L EKAGLY RAL++YT++ DIKR +V+T
Sbjct: 590  VLEVNLLHAPQVADAILGNNIFSHYDKPTIASLSEKAGLYQRALENYTDIKDIKRCVVHT 649

Query: 659  HAIEPQALVEFFGTLSKEWALECMKDLLLVNLRGNLQIIVQVAKEYCEQLGVDACIKIFE 718
            +A+    LV +FG L+ E +L C+K L+  N++ N+Q +VQVA ++ + +G    IK+FE
Sbjct: 650  NALPIDWLVGYFGKLNVEQSLACLKALMDNNIQANIQTVVQVATKFSDLIGPSTLIKLFE 709

Query: 719  QFRSYEGLYFFLGSYLSSSEDPDIHFKYIEAAAKTGQIKEVERVTRESSFYDPEKTKNFL 778
             + + EGLY++L S ++ +ED D+ +KYIEAAAK  Q +E+ER+ ++++ YDPE+ KNFL
Sbjct: 710  DYNATEGLYYYLASLVNLTEDKDVVYKYIEAAAKMKQYREIERIVKDNNVYDPERVKNFL 769

Query: 779  MEAKLPDARPLINVCDRFGFVPDLTHYLYTSNMLRYIEGYVQKVNPGNAPLVVGQLLDDE 838
             +A L D  PL+ VCDRF FV ++  YLY S  L++IE YVQ+VNP     VVG LLD +
Sbjct: 770  KDANLEDQLPLVIVCDRFDFVHEMILYLYKSQNLKFIETYVQQVNPSKTAQVVGALLDMD 829

Query: 839  CPEDFIKGLILSVRSLLPVEPLVAECEKRNRLRLLTQFLEHLVSEGSQDVHVHNALGKII 898
            C E FI+ L+ SV   +P+  L  E EKRNRL++L  FLE  +S+G QD  V+NAL KI 
Sbjct: 830  CDEAFIQSLLQSVLGQVPINELTTEVEKRNRLKILLPFLEQSLSQGIQDQAVYNALAKIY 889

Query: 899  IDSNNNPEHFLTTNPYYDSRVVGKYCEKRDPTLAVVAYRRGVCDDELINVTNKNSLFKLQ 958
            IDSNN+PE FL  N  YD+  VG YCEKRDP LA +AY +G  DD+LI +TN+NS++K Q
Sbjct: 890  IDSNNSPEKFLKENDQYDTLDVGHYCEKRDPYLAYIAYEKGQNDDDLIRITNENSMYKYQ 949

Query: 959  ARYVVERMDADLWEKVLNPDNTYRRQLIDQVVSTALPESKSPEQVSASVKAFMTADLPHE 1018
            ARY++ER D DLW KVLN +N +RRQLID V+S  +PE   PE VS +V+AFMT  L  E
Sbjct: 950  ARYLLERSDLDLWNKVLNQENIHRRQLIDSVISVGIPELTDPEPVSLTVQAFMTNGLKLE 1009

Query: 1019 LIELLEKIVLQNSAFSGNFNLQNLLILTAIKADSSRVMDYVNRLDNFDGPQVGEVAVEAE 1078
            LIELLEKI+L+ S F+ N  LQ LL+L+AIK + ++V  Y+ +LDN+D  ++  + +E +
Sbjct: 1010 LIELLEKIILEPSPFNENVALQGLLLLSAIKYEPTKVSSYIEKLDNYDADEIAPLCIEHD 1069

Query: 1079 LYEEAFAIFKKFNLNVQAVNVLLDNIHSIDRAVEFAFRVEEDAVWSQVAKAQLREGLVSD 1138
            L EEAF I+ K  +  +A+ VL+++I S+DRA  +A ++    +WSQ+  AQL    + D
Sbjct: 1070 LKEEAFEIYDKHEMYGKALKVLIEDIMSLDRAASYADKINTPELWSQIGTAQLDGLRIPD 1129

Query: 1139 AIESFIRADDATQFLDVIRAAQDGNAYQDLVRYLLMVRQKTKEPKVDSELIYAYAKIDRL 1198
            AIES+I+A+D + + +VI  A+    Y++L+ +LLM R+  KEPK+D  LI AYA+++++
Sbjct: 1130 AIESYIKAEDPSNYENVIDIAEQAGKYEELIPFLLMARKTLKEPKIDGALILAYAELNKI 1189

Query: 1199 SDIEEFILMPNVANLQNVGDRLYDEELYEAAKIIFAFISNWAKLAVTLVKLKQFQGAVDA 1258
             +IE  +   NVANL +VGD+L++ + Y+AA++ ++ +SN++KLA TLV L  +Q AVD 
Sbjct: 1190 HEIENLLAGSNVANLDHVGDKLFENKEYKAARLCYSAVSNYSKLASTLVYLGDYQAAVDT 1249

Query: 1259 ARKANSAKTWKEVCFACVDEEEFRLAQICGLNIIIQVDDLEEVSEYYQNRGCFNELISLM 1318
            ARKA++ K WK V  AC++++EF+LAQICGLN+I+  ++L+E+ E Y++ G F ELISL 
Sbjct: 1250 ARKASNIKVWKLVNDACIEKKEFKLAQICGLNLIVHAEELDELVERYESNGYFEELISLF 1309

Query: 1319 ESGLGLERAHMGIFTELGVLYARYRPEKLMEHIKLFATRLNIPKLIRACDEQQHWKELTY 1378
            E+GLGLERAHMG+FTEL +LY++Y P+K  EH+KLF +R+NIPK+IRA ++   W EL +
Sbjct: 1310 EAGLGLERAHMGMFTELAILYSKYEPDKTFEHLKLFWSRINIPKVIRAVEQAHLWSELVF 1369

Query: 1379 LYIQYDEFDNAATTIMNHSPEAWDHMQFKDVIAKVANVELYYKAVHFYLQEHPDLINDVL 1438
            LY  YDE+DNAA T++  S +  DH  FK+V+ KV+N+E+YYKA++FY++ HP L+ D+L
Sbjct: 1370 LYAHYDEWDNAALTLIEKSTKDLDHAYFKEVVVKVSNLEIYYKAINFYVKFHPSLLVDLL 1429

Query: 1439 NVLALRVDHARVVDIMRKAGHLRLVKPYMVAVQSNNVSAVNEALNEIYVEEEDYDRLRES 1498
              L  R+D  R V I  K+ +L L+KP+++ V   N S VN+A +++ +EEEDY  L+++
Sbjct: 1430 TSLTPRLDIPRTVKIFSKSDNLPLIKPFLINVLPKNNSVVNQAYHDLMIEEEDYKALQDA 1489

Query: 1499 IDLHDNFDQIGLAQKIEKHELLEMRRVAAYIYKKAGRWKQSIALSKKDNLYKDAMETASQ 1558
            +D +D FDQ+GLA ++E H+L+  +++ A +Y++  +W +S+++ K++ L+KDA+ETA+ 
Sbjct: 1490 VDSYDKFDQLGLASRLESHKLIFFKKIGALLYRRNKKWAKSLSILKEEKLWKDAIETAAI 1549

Query: 1559 SGERELAEELLVYFIDQGKKECFASCLFVCYDLIRVDVALELAWMHNMIDFAFPYLLQFI 1618
            S + ++ E LL YF++ G +E F + L+  Y+L+R++  LE++WM+++ D+  P+ +   
Sbjct: 1550 SQDPKVVEALLTYFVETGNREGFVALLYAAYNLVRIEFVLEISWMNSLEDYIKPFEISIK 1609

Query: 1619 REYTGKVDELVK 1630
            +E    + ++ +
Sbjct: 1610 KEQNDSIKKITE 1621


>DIA2_HUMAN (O60879) Diaphanous protein homolog 2 (Diaphanous-related
            formin 2) (DRF2)
          Length = 1101

 Score = 49.3 bits (116), Expect = 9e-05
 Identities = 36/104 (34%), Positives = 54/104 (51%), Gaps = 19/104 (18%)

Query: 1620 EYTGKVDELVKHKIESQNEVKAKEQEEKEV---IAQQNMYAQLL------PLALPAPPMP 1670
            E++ K DE    + E+Q E++ ++++ KE+   I Q    AQ+L      P    APP+P
Sbjct: 499  EFSKKFDEEFTARQEAQAELQKRDEKIKELEAEIQQLRTQAQVLSSSSGIPGPPAAPPLP 558

Query: 1671 GMGGG-------MGGGYA---PPPPMGGGMGMPPMPPFGMPMGG 1704
            G+G         + GG     PPPP+ G MG+PP PP  +  GG
Sbjct: 559  GVGPPPPPPAPPLPGGAPLPPPPPPLPGMMGIPPPPPPPLLFGG 602


>DIA2_MOUSE (O70566) Diaphanous protein homolog 2 (Diaphanous-related
            formin 2) (DRF2) (mDia3)
          Length = 1098

 Score = 48.5 bits (114), Expect = 2e-04
 Identities = 37/115 (32%), Positives = 55/115 (47%), Gaps = 20/115 (17%)

Query: 1607 IDFAFPYLL-------------QFIREYTGKVDELVKHKIESQNEVKAKEQEEKEVIAQ- 1652
            IDF F +LL             Q   E++ K DE    + E+Q E++ ++++ KE+  + 
Sbjct: 472  IDFDFTHLLDACVNKAKVEENEQKAMEFSKKFDEEFTARQEAQAELQKRDEKIKELETEI 531

Query: 1653 QNMYAQLLPLALPAPPMPGMGGGMGG------GYAPPPPMGGGMGMPPMPPFGMP 1701
            Q +  Q +P A+P PP P    G G          PPPP+ G +  PP P  GMP
Sbjct: 532  QQLRGQGVPSAIPGPPPPPPLPGAGPCPPPPPPPPPPPPLPGVVPPPPPPLPGMP 586


>DIA_DROME (P48608) Diaphanous protein
          Length = 1091

 Score = 46.2 bits (108), Expect = 8e-04
 Identities = 40/119 (33%), Positives = 46/119 (38%), Gaps = 36/119 (30%)

Query: 1620 EYTGKVDELVKHKIESQNEVKAKEQEEKEVIAQQNMYAQLLPLALPA------------- 1666
            EY  K+++L   K E+  E KA   EEK  + + N  A   P  LP              
Sbjct: 464  EYEKKIEQLESAKQEA--EAKAAHLEEKVKLMEANGVAAPSPNKLPKVNIPMPPPPPGGG 521

Query: 1667 -------PPMPGMGGG-------------MGGGYAPPPPMG-GGMGMPPMPPFGMPMGG 1704
                   PPMPG  GG              GG   PPPP G GG   PPMP    P GG
Sbjct: 522  GAPPPPPPPMPGRAGGGPPPPPPPPMPGRAGGPPPPPPPPGMGGPPPPPMPGMMRPGGG 580



 Score = 34.3 bits (77), Expect = 3.0
 Identities = 20/41 (48%), Positives = 22/41 (52%), Gaps = 9/41 (21%)

Query: 1665 PAPPMPGMGG-------GM--GGGYAPPPPMGGGMGMPPMP 1696
            P PP PGMGG       GM   GG  PPPPM  G  +P +P
Sbjct: 556  PPPPPPGMGGPPPPPMPGMMRPGGGPPPPPMMMGPMVPVLP 596


>PRA_MYCTU (O53426) Proline-rich antigen homolog
          Length = 240

 Score = 45.8 bits (107), Expect = 0.001
 Identities = 24/49 (48%), Positives = 24/49 (48%), Gaps = 12/49 (24%)

Query: 1665 PAPPMPGMGGGM---------GGGYAPPPPMGGGMGMPPMPPFGMPMGG 1704
            P PP PG  GG          G GYAPPPP   G G PP PP   P GG
Sbjct: 13   PPPPPPGPSGGHEPPPAAPPGGSGYAPPPPPSSGSGYPPPPP---PPGG 58



 Score = 37.7 bits (86), Expect = 0.27
 Identities = 17/33 (51%), Positives = 17/33 (51%), Gaps = 5/33 (15%)

Query: 1665 PAPPMPGMGGGMGGGYAPPPPMGGGMGMPPMPP 1697
            P PP PG     GG Y PPPP  GG   PP  P
Sbjct: 51   PPPPPPG-----GGAYPPPPPSAGGYAPPPPGP 78


>DIA3_HUMAN (Q9NSV4) Diaphanous protein homolog 3 (Diaphanous-related
            formin 3) (DRF3) (Fragment)
          Length = 853

 Score = 44.7 bits (104), Expect = 0.002
 Identities = 35/117 (29%), Positives = 53/117 (44%), Gaps = 14/117 (11%)

Query: 1594 VDVALELAWMHNMIDFAFPYLLQFIREYTGKVDELVKHKIESQNEVKAKEQEEKEVIAQQ 1653
            VD+ ++ A +    + A     +F +E+T        H+ E+Q E++ KE +  E+ A+ 
Sbjct: 236  VDICIDQAKLEEFEEKASELYKKFEKEFTD-------HQ-ETQAELQKKEAKINELQAEL 287

Query: 1654 NMYAQ---LLPLALPAPPMPGMGGGMGGGYAPPPP---MGGGMGMPPMPPFGMPMGG 1704
              +      LP     P  P   GG G    PPPP    GGG+  PP PP   P+ G
Sbjct: 288  QAFKSQFGALPADCNIPLPPSKEGGTGHSALPPPPPLPSGGGVPPPPPPPPPPPLPG 344



 Score = 43.1 bits (100), Expect = 0.007
 Identities = 20/40 (50%), Positives = 24/40 (60%), Gaps = 4/40 (10%)

Query: 1665 PAPPMPGMGGGMGGGYAPPPPMG--GGMGMPPMP--PFGM 1700
            P PP+PGM     G   PPPP+G  GG   PP+P  PFG+
Sbjct: 338  PPPPLPGMRMPFSGPVPPPPPLGFLGGQNSPPLPILPFGL 377


>SEPA_EMENI (P78621) Cytokinesis protein sepA (FH1/2 protein) (Forced
            expression inhibition of growth A)
          Length = 1790

 Score = 44.3 bits (103), Expect = 0.003
 Identities = 20/41 (48%), Positives = 22/41 (52%)

Query: 1665 PAPPMPGMGGGMGGGYAPPPPMGGGMGMPPMPPFGMPMGGY 1705
            P PP PG G        PPPP  GG+G PP PP   P GG+
Sbjct: 1040 PPPPPPGAGAAPPPPPPPPPPPPGGLGGPPPPPPPPPPGGF 1080



 Score = 43.9 bits (102), Expect = 0.004
 Identities = 22/43 (51%), Positives = 23/43 (53%), Gaps = 6/43 (13%)

Query: 1665 PAPPMPGMGGGMGGGYAPPPPMGGGMGMPPMPP------FGMP 1701
            P PP P   GG GG   PPPP GG  G PP PP      FG+P
Sbjct: 1069 PPPPPPPPPGGFGGPPPPPPPPGGFGGPPPPPPPPPGGAFGVP 1111



 Score = 42.4 bits (98), Expect = 0.011
 Identities = 21/42 (50%), Positives = 24/42 (57%), Gaps = 1/42 (2%)

Query: 1665 PAPPMPGMGGGMGGGYAPPPPMGGGMGM-PPMPPFGMPMGGY 1705
            P PP P  GG  G    PPPP GG  G+ PP PP G  +GG+
Sbjct: 1083 PPPPPPPPGGFGGPPPPPPPPPGGAFGVPPPPPPPGTVIGGW 1124



 Score = 42.0 bits (97), Expect = 0.015
 Identities = 22/42 (52%), Positives = 24/42 (56%), Gaps = 3/42 (7%)

Query: 1665 PAPPMPGMGGGMGGGYAPPPPM-GGGMGMPPMPPFGMPMGGY 1705
            P PP P   GG+GG   PPPP   GG G PP PP   P GG+
Sbjct: 1054 PPPPPPPPPGGLGGPPPPPPPPPPGGFGGPPPPP--PPPGGF 1093



 Score = 36.6 bits (83), Expect = 0.61
 Identities = 24/68 (35%), Positives = 27/68 (39%), Gaps = 3/68 (4%)

Query: 1640 KAKEQEEKEVIAQQNMYAQLLPLALPAPPMPGMGGGMGGGYAPPPPMGGGMGM---PPMP 1696
            K  EQ   + +A     A   P   P P  PG+ G       PPPP   G G    PP P
Sbjct: 997  KGDEQGVDDTVAVDKATAAPPPPPPPPPAHPGLSGAAPPPPPPPPPPPPGAGAAPPPPPP 1056

Query: 1697 PFGMPMGG 1704
            P   P GG
Sbjct: 1057 PPPPPPGG 1064


>DIA1_HUMAN (O60610) Diaphanous protein homolog 1 (Diaphanous-related
            formin 1) (DRF1)
          Length = 1248

 Score = 43.9 bits (102), Expect = 0.004
 Identities = 21/38 (55%), Positives = 23/38 (60%), Gaps = 6/38 (15%)

Query: 1665 PAPPMPGMGGGMGGGYAPPPPMGGGMGMPPMPP-FGMP 1701
            P PP+PG     G G  PPPP  GG G+PP PP  GMP
Sbjct: 695  PPPPLPG-----GPGIPPPPPFPGGPGIPPPPPGMGMP 727



 Score = 43.1 bits (100), Expect = 0.007
 Identities = 20/43 (46%), Positives = 23/43 (52%), Gaps = 9/43 (20%)

Query: 1665 PAPPMPGMGG---------GMGGGYAPPPPMGGGMGMPPMPPF 1698
            P PP+PG  G         G  G   PPPP+ GG G+PP PPF
Sbjct: 669  PPPPLPGSAGIPPPPPPLPGEAGMPPPPPPLPGGPGIPPPPPF 711



 Score = 38.5 bits (88), Expect = 0.16
 Identities = 24/52 (46%), Positives = 25/52 (47%), Gaps = 17/52 (32%)

Query: 1665 PAPPMPGMGGGM-------GGGYAPPPP--MGG--------GMGMPPMPPFG 1699
            P PP+PG  G         GG   PPPP   GG        GMGMPP PPFG
Sbjct: 682  PPPPLPGEAGMPPPPPPLPGGPGIPPPPPFPGGPGIPPPPPGMGMPPPPPFG 733



 Score = 37.4 bits (85), Expect = 0.36
 Identities = 24/80 (30%), Positives = 35/80 (43%), Gaps = 8/80 (10%)

Query: 1618 IREYTGKVDELVKHKIESQNEVKAKEQEEKEVIAQQNMYAQLLPLALPAPPMPGMGGGMG 1677
            + + TG+V +L K       E++  ++E   + A        +P   P PP P + G   
Sbjct: 532  VSQLTGEVAKLTK-------ELEDAKKEMASLSAAAITVPPSVPSRAPVPPAPPLPGD-S 583

Query: 1678 GGYAPPPPMGGGMGMPPMPP 1697
            G   PPPP  G    PP PP
Sbjct: 584  GTIIPPPPAPGDSTTPPPPP 603



 Score = 36.6 bits (83), Expect = 0.61
 Identities = 19/41 (46%), Positives = 23/41 (55%), Gaps = 6/41 (14%)

Query: 1665 PAPPMPGMGGGM-----GGGYAPPPPMGGGMGMPPMPPFGM 1700
            P PP PG G G+     G G  PPPP G G+   P+ PFG+
Sbjct: 707  PPPPFPG-GPGIPPPPPGMGMPPPPPFGFGVPAAPVLPFGL 746



 Score = 36.6 bits (83), Expect = 0.61
 Identities = 16/39 (41%), Positives = 21/39 (53%), Gaps = 5/39 (12%)

Query: 1665 PAPPMPGMGGGMGGGYAPPPPMGGGMGMPPMPPFGMPMG 1703
            P PP+PG     G   +PPPP+ G   +PP PP    +G
Sbjct: 608  PPPPLPG-----GTAISPPPPLSGDATIPPPPPLPEGVG 641



 Score = 33.1 bits (74), Expect = 6.7
 Identities = 18/40 (45%), Positives = 23/40 (57%), Gaps = 7/40 (17%)

Query: 1665 PAPPMP-GMG----GGMGGGYA--PPPPMGGGMGMPPMPP 1697
            P PP+P G+G      + GG A  PPPP+ G   +PP PP
Sbjct: 632  PPPPLPEGVGIPSPSSLPGGTAIPPPPPLPGSARIPPPPP 671


>SF01_HUMAN (Q15637) Splicing factor 1 (Zinc finger protein 162)
            (Transcription factor ZFM1) (Zinc finger gene in MEN1
            locus) (Mammalian branch point binding protein mBBP)
            (BBP)
          Length = 639

 Score = 43.1 bits (100), Expect = 0.007
 Identities = 24/53 (45%), Positives = 25/53 (46%), Gaps = 11/53 (20%)

Query: 1660 LPLALPAPPMPGMGGGMGGGYAPPPPMGG-----------GMGMPPMPPFGMP 1701
            LP   P PP P   G  G  YAPPPP              GMG+  MPPFGMP
Sbjct: 577  LPPGAPPPPPPPPPGSAGMMYAPPPPPPPPMDPSNFVTMMGMGVAGMPPFGMP 629


>DIA1_MOUSE (O08808) Diaphanous protein homolog 1 (Diaphanous-related
            formin 1) (DRF1) (mDIA1) (p140mDIA)
          Length = 1255

 Score = 43.1 bits (100), Expect = 0.007
 Identities = 27/80 (33%), Positives = 44/80 (54%), Gaps = 7/80 (8%)

Query: 1618 IREYTGKVDELVKHKIESQNEVKAKEQEEKEVIAQQNMYAQLLPLALPAPPMPGMGGGMG 1677
            + + TG+V +L K   +++NE+ +       V+A     +  +P   PAPP+PG  G + 
Sbjct: 532  VSKLTGEVAKLSKELEDAKNEMASLSAV---VVAPSVSSSAAVP---PAPPLPGDSGTVI 585

Query: 1678 GGYAPPPPMGGGMGMPPMPP 1697
                PPPP+ GG+ +PP PP
Sbjct: 586  PPPPPPPPLPGGV-VPPSPP 604



 Score = 40.4 bits (93), Expect = 0.042
 Identities = 21/49 (42%), Positives = 24/49 (48%), Gaps = 11/49 (22%)

Query: 1660 LPLALPAPPMPGMGGGMG-----------GGYAPPPPMGGGMGMPPMPP 1697
            LP A   PP P + GG G            G  PPPP+ GG G+PP PP
Sbjct: 665  LPGATAIPPPPPLPGGTGIPPPPPPLPGSVGVPPPPPLPGGPGLPPPPP 713



 Score = 39.3 bits (90), Expect = 0.094
 Identities = 22/51 (43%), Positives = 26/51 (50%), Gaps = 14/51 (27%)

Query: 1660 LPLALPAPPMPGMGGGMG-----------GGYAPPPPMGGGMGMPPMPPFG 1699
            LP ++  PP P + GG G            G  PPPP   GMG+PP PPFG
Sbjct: 690  LPGSVGVPPPPPLPGGPGLPPPPPPFPGAPGIPPPPP---GMGVPPPPPFG 737



 Score = 38.1 bits (87), Expect = 0.21
 Identities = 18/38 (47%), Positives = 21/38 (54%), Gaps = 2/38 (5%)

Query: 1660 LPLALPAPPMPGMGGGMGGGYAPPPPMGGGMGMPPMPP 1697
            LP A   PP P + G       PPPP+ GG G+PP PP
Sbjct: 653  LPGATAIPPPPPLPGAT--AIPPPPPLPGGTGIPPPPP 688



 Score = 37.0 bits (84), Expect = 0.47
 Identities = 18/40 (45%), Positives = 21/40 (52%), Gaps = 4/40 (10%)

Query: 1665 PAPPMPGMGG----GMGGGYAPPPPMGGGMGMPPMPPFGM 1700
            P PP PG  G      G G  PPPP G G+   P+ PFG+
Sbjct: 711  PPPPFPGAPGIPPPPPGMGVPPPPPFGFGVPAAPVLPFGL 750



 Score = 34.7 bits (78), Expect = 2.3
 Identities = 14/33 (42%), Positives = 18/33 (54%), Gaps = 5/33 (15%)

Query: 1665 PAPPMPGMGGGMGGGYAPPPPMGGGMGMPPMPP 1697
            P PP+PG+         PPPP+ G   +PP PP
Sbjct: 637  PPPPLPGVAS-----IPPPPPLPGATAIPPPPP 664



 Score = 33.9 bits (76), Expect = 4.0
 Identities = 17/40 (42%), Positives = 21/40 (52%), Gaps = 6/40 (15%)

Query: 1665 PAPPMPGMGGGMGGGYAPPPPMGGGMGM-PPMPPFGMPMG 1703
            P PP+PG          PPPP+ GG G+ PP PP    +G
Sbjct: 661  PPPPLPG-----ATAIPPPPPLPGGTGIPPPPPPLPGSVG 695


>FMN2_MOUSE (Q9JL04) Formin 2
          Length = 1567

 Score = 42.4 bits (98), Expect = 0.011
 Identities = 23/45 (51%), Positives = 26/45 (57%), Gaps = 10/45 (22%)

Query: 1660 LPLALPAPPMPGMG-------GGMGGGYAPPPPMGGGMGMPPMPP 1697
            +P   PAPP+PGMG        GMG    PPPP   GMG+PP PP
Sbjct: 907  VPPPPPAPPLPGMGIPPPPPLPGMG---IPPPPPLPGMGIPPPPP 948



 Score = 39.3 bits (90), Expect = 0.094
 Identities = 19/37 (51%), Positives = 21/37 (56%)

Query: 1661 PLALPAPPMPGMGGGMGGGYAPPPPMGGGMGMPPMPP 1697
            P  LPAPP P    G+G    PP P   GMG+PP PP
Sbjct: 890  PEMLPAPPQPPPLPGLGVPPPPPAPPLPGMGIPPPPP 926



 Score = 38.5 bits (88), Expect = 0.16
 Identities = 21/50 (42%), Positives = 26/50 (52%), Gaps = 13/50 (26%)

Query: 1658 QLLPLALPAPPMPGMG----------GGMGGGYAPPPPMGGGMGMPPMPP 1697
            ++LP     PP+PG+G           GMG    PPPP   GMG+PP PP
Sbjct: 891  EMLPAPPQPPPLPGLGVPPPPPAPPLPGMG---IPPPPPLPGMGIPPPPP 937



 Score = 38.1 bits (87), Expect = 0.21
 Identities = 17/33 (51%), Positives = 20/33 (60%), Gaps = 7/33 (21%)

Query: 1665 PAPPMPGMGGGMGGGYAPPPPMGGGMGMPPMPP 1697
            P PP+PG+G        PPPP   GMG+PP PP
Sbjct: 1011 PPPPLPGVG-------IPPPPPLPGMGIPPPPP 1036



 Score = 37.7 bits (86), Expect = 0.27
 Identities = 18/37 (48%), Positives = 22/37 (58%), Gaps = 4/37 (10%)

Query: 1665 PAPPMPGMG----GGMGGGYAPPPPMGGGMGMPPMPP 1697
            P PP+PGMG      + G   PPPP   G+G+PP PP
Sbjct: 934  PPPPLPGMGIPPPPPLPGVGIPPPPPLPGVGIPPPPP 970



 Score = 37.0 bits (84), Expect = 0.47
 Identities = 17/37 (45%), Positives = 21/37 (55%), Gaps = 4/37 (10%)

Query: 1665 PAPPMPGMG----GGMGGGYAPPPPMGGGMGMPPMPP 1697
            P PP+PGMG      + G   PPPP   G+ +PP PP
Sbjct: 1022 PPPPLPGMGIPPPPPLPGSGIPPPPALPGVAIPPPPP 1058



 Score = 36.6 bits (83), Expect = 0.61
 Identities = 16/33 (48%), Positives = 20/33 (60%), Gaps = 7/33 (21%)

Query: 1665 PAPPMPGMGGGMGGGYAPPPPMGGGMGMPPMPP 1697
            P PP+PG+G        PPPP   G+G+PP PP
Sbjct: 967  PPPPLPGVG-------IPPPPPLPGVGIPPPPP 992



 Score = 36.6 bits (83), Expect = 0.61
 Identities = 16/33 (48%), Positives = 20/33 (60%), Gaps = 7/33 (21%)

Query: 1665 PAPPMPGMGGGMGGGYAPPPPMGGGMGMPPMPP 1697
            P PP+PG+G        PPPP   G+G+PP PP
Sbjct: 989  PPPPLPGVG-------IPPPPPLPGVGIPPPPP 1014



 Score = 36.6 bits (83), Expect = 0.61
 Identities = 16/33 (48%), Positives = 20/33 (60%), Gaps = 7/33 (21%)

Query: 1665 PAPPMPGMGGGMGGGYAPPPPMGGGMGMPPMPP 1697
            P PP+PG+G        PPPP   G+G+PP PP
Sbjct: 956  PPPPLPGVG-------IPPPPPLPGVGIPPPPP 981



 Score = 36.6 bits (83), Expect = 0.61
 Identities = 16/33 (48%), Positives = 20/33 (60%), Gaps = 7/33 (21%)

Query: 1665 PAPPMPGMGGGMGGGYAPPPPMGGGMGMPPMPP 1697
            P PP+PG+G        PPPP   G+G+PP PP
Sbjct: 1000 PPPPLPGVG-------IPPPPPLPGVGIPPPPP 1025



 Score = 36.6 bits (83), Expect = 0.61
 Identities = 16/33 (48%), Positives = 20/33 (60%), Gaps = 7/33 (21%)

Query: 1665 PAPPMPGMGGGMGGGYAPPPPMGGGMGMPPMPP 1697
            P PP+PG+G        PPPP   G+G+PP PP
Sbjct: 978  PPPPLPGVG-------IPPPPPLPGVGIPPPPP 1003



 Score = 35.0 bits (79), Expect = 1.8
 Identities = 17/37 (45%), Positives = 20/37 (53%), Gaps = 4/37 (10%)

Query: 1665 PAPPMPGMG----GGMGGGYAPPPPMGGGMGMPPMPP 1697
            P PP+PG G      + G   PPPP   GMG+PP  P
Sbjct: 1033 PPPPLPGSGIPPPPALPGVAIPPPPPLPGMGVPPPAP 1069



 Score = 32.7 bits (73), Expect = 8.8
 Identities = 18/37 (48%), Positives = 21/37 (56%), Gaps = 4/37 (10%)

Query: 1665 PAPPMPGMGGGMGGGYAPPPPMGGGMGMPPMPPFGMP 1701
            P PP+PGMG       APPPP G G+  PP+ P   P
Sbjct: 1055 PPPPLPGMGVPPP---APPPP-GAGIPPPPLLPGSGP 1087


>SMR1_MOUSE (Q61900) Submaxillary gland androgen regulated protein 1
            precursor (Salivary protein MSG1)
          Length = 147

 Score = 41.2 bits (95), Expect = 0.025
 Identities = 19/37 (51%), Positives = 23/37 (61%), Gaps = 2/37 (5%)

Query: 1667 PPMPGMGGGMGGGYAPPPPMGGGMGMPPMPPFGMPMG 1703
            PP P  G G+G  +  PPP G G+G PP PPFG  +G
Sbjct: 37   PPPPPHGPGIGRPH--PPPFGPGIGRPPPPPFGPGIG 71



 Score = 38.9 bits (89), Expect = 0.12
 Identities = 21/44 (47%), Positives = 23/44 (51%), Gaps = 7/44 (15%)

Query: 1661 PLALPAPPM-PGMGG------GMGGGYAPPPPMGGGMGMPPMPP 1697
            P   P PP  PG+G       G G G  PPPP G G+G PP PP
Sbjct: 34   PFPPPPPPHGPGIGRPHPPPFGPGIGRPPPPPFGPGIGRPPPPP 77


  Database: sprot
    Posted date:  Nov 25, 2004 10:54 AM
  Number of letters in database: 59,974,054
  Number of sequences in database:  164,201
  
Lambda     K      H
   0.320    0.137    0.394 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 196,768,431
Number of Sequences: 164201
Number of extensions: 8574490
Number of successful extensions: 30364
Number of sequences better than 10.0: 143
Number of HSP's better than 10.0 without gapping: 42
Number of HSP's successfully gapped in prelim test: 106
Number of HSP's that attempted gapping in prelim test: 29087
Number of HSP's gapped (non-prelim): 738
length of query: 1705
length of database: 59,974,054
effective HSP length: 124
effective length of query: 1581
effective length of database: 39,613,130
effective search space: 62628358530
effective search space used: 62628358530
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 73 (32.7 bits)