BLAST2 result
BLASTP 2.2.2 [Dec-14-2001]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= AC142396.3 - phase: 0
(432 letters)
Database: sprot
164,201 sequences; 59,974,054 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
FEM2_HUMAN (P49593) Ca(2+)/calmodulin-dependent protein kinase p... 86 1e-16
P2C2_ARATH (O04719) Protein phosphatase 2C ABI2 (EC 3.1.3.16) (P... 79 2e-14
PDP2_HUMAN (Q9P2J9) [Pyruvate dehydrogenase [Lipoamide]]-phospha... 79 2e-14
P2CA_RAT (P20650) Protein phosphatase 2C alpha isoform (EC 3.1.3... 79 3e-14
P2CA_RABIT (P35814) Protein phosphatase 2C alpha isoform (EC 3.1... 79 3e-14
P2CA_HUMAN (P35813) Protein phosphatase 2C alpha isoform (EC 3.1... 79 3e-14
P2CA_MOUSE (P49443) Protein phosphatase 2C alpha isoform (EC 3.1... 78 4e-14
P2C2_CAEEL (P49596) Probable protein phosphatase 2C T23F11.1 (EC... 78 4e-14
P2CA_BOVIN (O62829) Protein phosphatase 2C alpha isoform (EC 3.1... 78 5e-14
P2C3_SCHPO (Q09173) Protein phosphatase 2C homolog 3 (EC 3.1.3.1... 77 1e-13
FEM2_RAT (Q9WVR7) Ca(2+)/calmodulin-dependent protein kinase pho... 75 3e-13
P2C2_SCHPO (Q09172) Protein phosphatase 2C homolog 2 (EC 3.1.3.1... 74 6e-13
P2CB_BOVIN (O62830) Protein phosphatase 2C beta isoform (EC 3.1.... 74 9e-13
P2C_PARTE (P49444) Protein phosphatase 2C (EC 3.1.3.16) (PP2C) 73 2e-12
PDP2_RAT (O88484) [Pyruvate dehydrogenase [Lipoamide]]-phosphata... 72 2e-12
P2CB_MOUSE (P36993) Protein phosphatase 2C beta isoform (EC 3.1.... 72 2e-12
P2C1_SCHPO (P40371) Protein phosphatase 2C homolog 1 (EC 3.1.3.1... 72 3e-12
P2CB_HUMAN (O75688) Protein phosphatase 2C beta isoform (EC 3.1.... 72 4e-12
P2CB_RAT (P35815) Protein phosphatase 2C beta isoform (EC 3.1.3.... 71 5e-12
P2C5_YEAST (Q12511) Protein phosphatase 2C homolog 5 (EC 3.1.3.1... 70 8e-12
>FEM2_HUMAN (P49593) Ca(2+)/calmodulin-dependent protein kinase
phosphatase (EC 3.1.3.16) (CaM-kinase phosphatase)
(CaMKPase) (Partner of PIX 2) (hFEM-2) (Protein
phosphatase 1F)
Length = 454
Score = 86.3 bits (212), Expect = 1e-16
Identities = 79/282 (28%), Positives = 125/282 (44%), Gaps = 58/282 (20%)
Query: 65 NAVFLGIYDGHGGTQASRFICEHLFKNLLRFANDNENDITEATLRNAVSATEEGFLDFAK 124
N + ++DGHGG A+R+ H+ N R E LR A T++ FL AK
Sbjct: 190 NRAYFAVFDGHGGVDAARYAAVHVHTNAAR--QPELPTDPEGALREAFRRTDQMFLRKAK 247
Query: 125 MNYMHQPNLGYVGSCCLAGIIWKETLHVANLGDSRVVIGTMVNKKIRAEQLTRDHNCNDE 184
+ G G C L I TLHVA LGDS+V++ + ++ + R +++
Sbjct: 248 RERLQS---GTTGVCAL---IAGATLHVAWLGDSQVIL-VQQGQVVKLMEPHRPERQDEK 300
Query: 185 AIREELRAMHPDDPNVVINDNGSWRVKGFITVSRAIGDAYLKRSEFTLRESFPKLEIVPE 244
A E L ++ WRV G + VSRAIGD + K
Sbjct: 301 ARIEALGGF--------VSHMDCWRVNGTLAVSRAIGDVFQK------------------ 334
Query: 245 PFTRGVLSAEPEMHTRVLTDNDQFIIFASDGLWDFLSNKKAAEIVQKNPRNGIAKRLLST 304
P+ +S E + +R LT ++ +++ A DG +D + +++ +VQ + R +
Sbjct: 335 PY----VSGEADAASRALTGSEDYLLLACDGFFDVVPHQEVVGLVQSH-----LTRQQGS 385
Query: 305 ALAVAAKRRKVTYRKIQAAATGRNNVSRRSFHDDISVIVVFL 346
L VA ++ AAA R + HD+I+V+VVFL
Sbjct: 386 GLRVA--------EELVAAARERGS------HDNITVMVVFL 413
>P2C2_ARATH (O04719) Protein phosphatase 2C ABI2 (EC 3.1.3.16)
(PP2C) (Abscisic acid-insensitive 2)
Length = 423
Score = 79.3 bits (194), Expect = 2e-14
Identities = 83/297 (27%), Positives = 132/297 (43%), Gaps = 57/297 (19%)
Query: 65 NAVFLGIYDGHGGTQASRF--------ICEHLFKNLLRFAN-DNENDITEATLRNAVSAT 115
+A F G+YDGHGG+Q + + + E + K F + D + + L N+
Sbjct: 157 SAHFFGVYDGHGGSQVANYCRERMHLALTEEIVKEKPEFCDGDTWQEKWKKALFNSFMRV 216
Query: 116 EEGFLDFAKMNYMHQPNLGYVGSCCLAGIIWKETLHVANLGDSRVVIGTMVNKKIRAEQL 175
+ A H P VGS + +++ + VAN GDSR V+ K A +
Sbjct: 217 DSEIETVA-----HAPET--VGSTSVVAVVFPTHIFVANCGDSRAVLCR--GKTPLALSV 267
Query: 176 TRDHNCNDEAIREELRAMHPDDPNVVINDNGSWRVKGFITVSRAIGDAYLKRSEFTLRES 235
+ +DEA R E VI NG+ RV G + +SR+IGD YLK S
Sbjct: 268 DHKPDRDDEAARIEAAG------GKVIRWNGA-RVFGVLAMSRSIGDRYLKPS------- 313
Query: 236 FPKLEIVPEPFTRGVLSAEPEMHTRVLTDNDQFIIFASDGLWDFLSNKKAAEIVQK---- 291
++P+P V + D +I ASDGLWD ++N++ ++ +K
Sbjct: 314 -----VIPDPEVTSVRRVK----------EDDCLILASDGLWDVMTNEEVCDLARKRILL 358
Query: 292 -NPRNGIAKRLLSTALAVAAKRRKVTYRKIQAAATGRNNVS-RRSFHDDISVIVVFL 346
+ +N +A AL A KR + +AA + ++ ++ D+ISV+VV L
Sbjct: 359 WHKKNAMA----GEALLPAEKRGEGKDPAAMSAAEYLSKMALQKGSKDNISVVVVDL 411
>PDP2_HUMAN (Q9P2J9) [Pyruvate dehydrogenase
[Lipoamide]]-phosphatase 2, mitochondrial precursor (EC
3.1.3.43) (PDP 2) (Pyruvate dehydrogenase phosphatase,
catalytic subunit 2) (PDPC 2)
Length = 529
Score = 79.0 bits (193), Expect = 2e-14
Identities = 54/153 (35%), Positives = 77/153 (50%), Gaps = 17/153 (11%)
Query: 150 LHVANLGDSRVVIGTMVNKKI-RAEQLTRDHNCNDEAIREELRAMHPD--DPNVVINDNG 206
LHVAN GD R ++G + + LTRDHN ++A L+ HP+ D +++ D
Sbjct: 279 LHVANAGDCRAILGVQEDNGMWSCLPLTRDHNAWNQAELSRLKREHPESEDRTIIMED-- 336
Query: 207 SWRVKGFITVSRAIGDAYLKRSEFTLRESFPK------LEIV----PEPFTRGVLSAEPE 256
R+ G + RA GD LK S+ R + L I P +T L+AEPE
Sbjct: 337 --RLLGVLIPCRAFGDVQLKWSKELQRSILERGFNTEALNIYQFTPPHYYTPPYLTAEPE 394
Query: 257 MHTRVLTDNDQFIIFASDGLWDFLSNKKAAEIV 289
+ L D+F++ ASDGLWD LSN+ +V
Sbjct: 395 VTYHRLRPQDKFLVLASDGLWDMLSNEDVVRLV 427
Score = 35.8 bits (81), Expect = 0.22
Identities = 17/49 (34%), Positives = 27/49 (54%), Gaps = 1/49 (2%)
Query: 42 FSSAVVQANTTMEDQSQI-EVASNNAVFLGIYDGHGGTQASRFICEHLF 89
F S + AN+ +ED+ + N + GI+DGHGG ++ + E LF
Sbjct: 109 FESNQLAANSPVEDRRGVASCLQTNGLMFGIFDGHGGHACAQAVSERLF 157
>P2CA_RAT (P20650) Protein phosphatase 2C alpha isoform (EC
3.1.3.16) (PP2C-alpha) (IA) (Protein phosphatase 1A)
Length = 382
Score = 78.6 bits (192), Expect = 3e-14
Identities = 64/230 (27%), Positives = 107/230 (45%), Gaps = 36/230 (15%)
Query: 68 FLGIYDGHGGTQASRFICEHLFKNLLRFANDNENDITEATLRNAVSATEEGFLDFAK-MN 126
F +YDGH G+Q +++ CEHL ++ D + ++ N + GFL+ + M
Sbjct: 55 FFAVYDGHAGSQVAKYCCEHLLDHITN-NQDFKGSAGAPSVENVKNGIRTGFLEIDEHMR 113
Query: 127 YMHQPNLG--YVGSCCLAGIIWKETLHVANLGDSRVVIGTMVNKKIRAEQLTRDHNCNDE 184
M + G GS + +I + + N GDSR ++ N+K+ T+DH ++
Sbjct: 114 VMSEKKHGADRSGSTAVGVLISPQHTYFINCGDSRGLL--CRNRKVHF--FTQDHKPSNP 169
Query: 185 AIREELRAMHPDDPNVVINDNGS---WRVKGFITVSRAIGDAYLKRSEFTLRESFPKLEI 241
+E ++ N GS RV G + VSRA+GD F +
Sbjct: 170 LEKERIQ-----------NAGGSVMIQRVNGSLAVSRALGD-------------FDYKCV 205
Query: 242 VPEPFTRGVLSAEPEMH-TRVLTDNDQFIIFASDGLWDFLSNKKAAEIVQ 290
+ T ++S EPE+H ++DQFII A DG+WD + N++ + V+
Sbjct: 206 HGKGPTEQLVSPEPEVHDIERSEEDDQFIILACDGIWDVMGNEELCDFVR 255
>P2CA_RABIT (P35814) Protein phosphatase 2C alpha isoform (EC
3.1.3.16) (PP2C-alpha) (IA) (Protein phosphatase 1A)
Length = 382
Score = 78.6 bits (192), Expect = 3e-14
Identities = 64/230 (27%), Positives = 107/230 (45%), Gaps = 36/230 (15%)
Query: 68 FLGIYDGHGGTQASRFICEHLFKNLLRFANDNENDITEATLRNAVSATEEGFLDFAK-MN 126
F +YDGH G+Q +++ CEHL ++ D + ++ N + GFL+ + M
Sbjct: 55 FFAVYDGHAGSQVAKYCCEHLLDHITN-NQDFKGSAGAPSVENVKNGIRTGFLEIDEHMR 113
Query: 127 YMHQPNLG--YVGSCCLAGIIWKETLHVANLGDSRVVIGTMVNKKIRAEQLTRDHNCNDE 184
M + G GS + +I + + N GDSR ++ N+K+ T+DH ++
Sbjct: 114 VMSEKKHGADRSGSTAVGVLISPQHTYFINCGDSRGLL--CRNRKVHF--FTQDHKPSNP 169
Query: 185 AIREELRAMHPDDPNVVINDNGS---WRVKGFITVSRAIGDAYLKRSEFTLRESFPKLEI 241
+E ++ N GS RV G + VSRA+GD F +
Sbjct: 170 LEKERIQ-----------NAGGSVMIQRVNGSLAVSRALGD-------------FDYKCV 205
Query: 242 VPEPFTRGVLSAEPEMH-TRVLTDNDQFIIFASDGLWDFLSNKKAAEIVQ 290
+ T ++S EPE+H ++DQFII A DG+WD + N++ + V+
Sbjct: 206 HGKGPTEQLVSPEPEVHDIERSEEDDQFIILACDGIWDVMGNEELCDFVR 255
>P2CA_HUMAN (P35813) Protein phosphatase 2C alpha isoform (EC
3.1.3.16) (PP2C-alpha) (IA) (Protein phosphatase 1A)
Length = 382
Score = 78.6 bits (192), Expect = 3e-14
Identities = 64/230 (27%), Positives = 107/230 (45%), Gaps = 36/230 (15%)
Query: 68 FLGIYDGHGGTQASRFICEHLFKNLLRFANDNENDITEATLRNAVSATEEGFLDFAK-MN 126
F +YDGH G+Q +++ CEHL ++ D + ++ N + GFL+ + M
Sbjct: 55 FFAVYDGHAGSQVAKYCCEHLLDHITN-NQDFKGSAGAPSVENVKNGIRTGFLEIDEHMR 113
Query: 127 YMHQPNLG--YVGSCCLAGIIWKETLHVANLGDSRVVIGTMVNKKIRAEQLTRDHNCNDE 184
M + G GS + +I + + N GDSR ++ N+K+ T+DH ++
Sbjct: 114 VMSEKKHGADRSGSTAVGVLISPQHTYFINCGDSRGLL--CRNRKVHF--FTQDHKPSNP 169
Query: 185 AIREELRAMHPDDPNVVINDNGS---WRVKGFITVSRAIGDAYLKRSEFTLRESFPKLEI 241
+E ++ N GS RV G + VSRA+GD F +
Sbjct: 170 LEKERIQ-----------NAGGSVMIQRVNGSLAVSRALGD-------------FDYKCV 205
Query: 242 VPEPFTRGVLSAEPEMH-TRVLTDNDQFIIFASDGLWDFLSNKKAAEIVQ 290
+ T ++S EPE+H ++DQFII A DG+WD + N++ + V+
Sbjct: 206 HGKGPTEQLVSPEPEVHDIERSEEDDQFIILACDGIWDVMGNEELCDFVR 255
>P2CA_MOUSE (P49443) Protein phosphatase 2C alpha isoform (EC
3.1.3.16) (PP2C-alpha) (IA) (Protein phosphatase 1A)
Length = 382
Score = 78.2 bits (191), Expect = 4e-14
Identities = 64/230 (27%), Positives = 106/230 (45%), Gaps = 36/230 (15%)
Query: 68 FLGIYDGHGGTQASRFICEHLFKNLLRFANDNENDITEATLRNAVSATEEGFLDFAK-MN 126
F +YDGH G+Q +++ CEHL ++ D ++ N + GFL+ + M
Sbjct: 55 FFAVYDGHAGSQVAKYCCEHLLDHITN-NQDFRGSAGAPSVENVKNGIRTGFLEIDEHMR 113
Query: 127 YMHQPNLG--YVGSCCLAGIIWKETLHVANLGDSRVVIGTMVNKKIRAEQLTRDHNCNDE 184
M + G GS + +I + + N GDSR ++ N+K+ T+DH ++
Sbjct: 114 VMSEKKHGADRSGSTAVGVLISPQHTYFINCGDSRGLL--CRNRKVHF--FTQDHKPSNP 169
Query: 185 AIREELRAMHPDDPNVVINDNGS---WRVKGFITVSRAIGDAYLKRSEFTLRESFPKLEI 241
+E ++ N GS RV G + VSRA+GD F +
Sbjct: 170 LEKERIQ-----------NAGGSVMIQRVNGSLAVSRALGD-------------FDYKCV 205
Query: 242 VPEPFTRGVLSAEPEMH-TRVLTDNDQFIIFASDGLWDFLSNKKAAEIVQ 290
+ T ++S EPE+H ++DQFII A DG+WD + N++ + V+
Sbjct: 206 HGKGPTEQLVSPEPEVHDIERSEEDDQFIILACDGIWDVMGNEELCDFVR 255
>P2C2_CAEEL (P49596) Probable protein phosphatase 2C T23F11.1 (EC
3.1.3.16) (PP2C)
Length = 356
Score = 78.2 bits (191), Expect = 4e-14
Identities = 63/250 (25%), Positives = 112/250 (44%), Gaps = 47/250 (18%)
Query: 68 FLGIYDGHGGTQASRFICEHLFKNLLRFANDNENDITEATLRNAVSATEEGFLDFAKMNY 127
F +YDGHGG++ S++ +L K ++ + + +E ++ A+ E+GFL+ +
Sbjct: 54 FFAVYDGHGGSKVSQYSGINLHKKVVA-----QKEFSEGNMKEAI---EKGFLELDQQMR 105
Query: 128 MHQPNLGYVGSCCLAGIIWKE-TLHVANLGDSRVVIGTMVNKKIRAEQLTRDHNCNDEAI 186
+ + V ++ KE ++ N GDSR V + A L+ DH + E
Sbjct: 106 VDEETKDDVSGTTAVVVLIKEGDVYCGNAGDSRAVSSVVGE----ARPLSFDHKPSHETE 161
Query: 187 REELRAMHPDDPNVVINDNGSW----RVKGFITVSRAIGDAYLKRSEFTLRESFPKLEIV 242
+ A G W RV G + +SRA+GD K +
Sbjct: 162 ARRIIAA------------GGWVEFNRVNGNLALSRALGDFAFKNCD------------- 196
Query: 243 PEPFTRGVLSAEPEMHTRVLTDNDQFIIFASDGLWDFLSNKKAAEIV-----QKNPRNGI 297
+P +++A P++ T LT + +FI+ A DG+WD ++N++ + V +K I
Sbjct: 197 TKPAEEQIVTAFPDVITDKLTPDHEFIVLACDGIWDVMTNQEVVDFVREKLAEKRDPQSI 256
Query: 298 AKRLLSTALA 307
+ LL+ LA
Sbjct: 257 CEELLTRCLA 266
>P2CA_BOVIN (O62829) Protein phosphatase 2C alpha isoform (EC
3.1.3.16) (PP2C-alpha)
Length = 382
Score = 77.8 bits (190), Expect = 5e-14
Identities = 64/230 (27%), Positives = 107/230 (45%), Gaps = 36/230 (15%)
Query: 68 FLGIYDGHGGTQASRFICEHLFKNLLRFANDNENDITEATLRNAVSATEEGFLDFAK-MN 126
F +YDGH G+Q +++ CEHL ++ D + ++ N + GFL+ + M
Sbjct: 55 FFAVYDGHAGSQVAKYCCEHLLDHITN-NQDFKGSAGAPSVENVKNGIRTGFLEIDEHMR 113
Query: 127 YMHQPNLG--YVGSCCLAGIIWKETLHVANLGDSRVVIGTMVNKKIRAEQLTRDHNCNDE 184
M + G GS + +I + + N GDSR ++ N+K+ T+DH ++
Sbjct: 114 VMSEKKHGADRSGSTAVGVLISPQHTYFINCGDSRGLL--CRNRKVYF--FTQDHKPSNP 169
Query: 185 AIREELRAMHPDDPNVVINDNGS---WRVKGFITVSRAIGDAYLKRSEFTLRESFPKLEI 241
+E ++ N GS RV G + VSRA+GD F +
Sbjct: 170 LEKERIQ-----------NAGGSVMIQRVNGSLAVSRALGD-------------FDYKCV 205
Query: 242 VPEPFTRGVLSAEPEMH-TRVLTDNDQFIIFASDGLWDFLSNKKAAEIVQ 290
+ T ++S EPE+H ++DQFII A DG+WD + N++ + V+
Sbjct: 206 HGKGPTEQLVSPEPEVHDIERSEEDDQFIILACDGIWDVMGNEELCDFVR 255
>P2C3_SCHPO (Q09173) Protein phosphatase 2C homolog 3 (EC 3.1.3.16)
(PP2C-3)
Length = 414
Score = 76.6 bits (187), Expect = 1e-13
Identities = 68/247 (27%), Positives = 120/247 (48%), Gaps = 42/247 (17%)
Query: 68 FLGIYDGHGGTQASRFICEHLFKNLLRFANDNENDITEATLRNAVSATEEGFLDFAKMNY 127
F +YDGHGG + +++ +L + L + + + D A L+++ ++ LD +
Sbjct: 57 FFAVYDGHGGDKVAKWCGSNLPQILEKNPDFQKGDFVNA-LKSSFLNADKAILDD---DQ 112
Query: 128 MHQPNLGYVGSCCLAGIIWK--ETLHVANLGDSRVVIGTMVNKKIRAEQLTRDHNCNDEA 185
H G C A ++ + L+ AN GDSR V+G+ K A+ L+ DH ++EA
Sbjct: 113 FHTDPSG-----CTATVVLRVGNKLYCANAGDSRTVLGS----KGIAKPLSADHKPSNEA 163
Query: 186 IREELRAMHPDDPNVVINDNGSWRVKGFITVSRAIGDAYLKRSEFTLRESFPKLEIVPEP 245
+ + A D G RV G + +SRAIGD K S + PE
Sbjct: 164 EKARICAAGG------FVDFG--RVNGNLALSRAIGDFEFKNSN-----------LEPE- 203
Query: 246 FTRGVLSAEPEMHTRVLTDNDQFIIFASDGLWDFLSNKKAAEIVQKNPRNG-----IAKR 300
+ +++A P++ +TD+D+F++ A DG+WD ++++ E V++ G IA+
Sbjct: 204 --KQIVTALPDVVVHEITDDDEFVVLACDGIWDCKTSQQVIEFVRRGIVAGTSLEKIAEN 261
Query: 301 LLSTALA 307
L+ +A
Sbjct: 262 LMDNCIA 268
>FEM2_RAT (Q9WVR7) Ca(2+)/calmodulin-dependent protein kinase
phosphatase (EC 3.1.3.16) (CaM-kinase phosphatase)
(CaMKPase) (Partner of PIX 2) (Protein phosphatase 1F)
Length = 450
Score = 75.1 bits (183), Expect = 3e-13
Identities = 83/320 (25%), Positives = 136/320 (41%), Gaps = 68/320 (21%)
Query: 63 SNNAVFLGIYDGHGGTQASRFICEHLFKNLLRFANDNENDITE--ATLRNAVSATEEGFL 120
S + + ++DGHGG A+R+ H+ N A+ +T+ A L+ A T++ FL
Sbjct: 184 SVHRAYFAVFDGHGGVDAARYASVHVHTN----ASHQPELLTDPAAALKEAFRHTDQMFL 239
Query: 121 DFAKMNYMHQPNLGYVGSCCLAGIIWKETLHVANLGDSRVVIGTMVNKKIRAEQLTRDHN 180
AK + G G C L I LHVA LGDS+V++ ++ + +L H
Sbjct: 240 QKAKRERLQS---GTTGVCAL---ITGAALHVAWLGDSQVILV----QQGQVVKLMEPHK 289
Query: 181 CNDEAIREELRAMHPDDPNVVINDNGSWRVKGFITVSRAIGDAYLKRSEFTLRESFPKLE 240
+ + + A+ ++ WRV G + VSRAIGD + K
Sbjct: 290 PERQDEKSRIEAL-----GGFVSLMDCWRVNGTLAVSRAIGDVFQK-------------- 330
Query: 241 IVPEPFTRGVLSAEPEMHTRVLTDNDQFIIFASDGLWDFLSNKKAAEIVQKNPRNGIAKR 300
P+ +S E + +R LT + +++ A DG +D + + + +V +G R
Sbjct: 331 ----PY----VSGEADAASRELTGLEDYLLLACDGFFDVVPHHEIPGLV-----HGHLLR 377
Query: 301 LLSTALAVAAKRRKVTYRKIQAAATGRNNVSRRSFHDDISVIVVFLDKTSFPRQPVLNLS 360
+ + VA + A R+ R HD+I+V+VVFL R P+ L
Sbjct: 378 QKGSGMHVAE----------ELVAVARD----RGSHDNITVMVVFL------RDPLELLE 417
Query: 361 YTGSSDRPVQSDFAQFGLTT 380
G Q+D L+T
Sbjct: 418 GGGQGAGGAQADVGSQDLST 437
>P2C2_SCHPO (Q09172) Protein phosphatase 2C homolog 2 (EC 3.1.3.16)
(PP2C-2)
Length = 370
Score = 74.3 bits (181), Expect = 6e-13
Identities = 69/239 (28%), Positives = 111/239 (45%), Gaps = 47/239 (19%)
Query: 68 FLGIYDGHGGTQASRFICEHL---FKNLLRFANDNENDITEATLRNAVSATEEGFLDFAK 124
F G++DGHGG + +++ +HL K+ F N ++ A + GFL A
Sbjct: 58 FFGVFDGHGGDRVAKYCRQHLPDIIKSQPSFWKGNYDE-----------ALKSGFLA-AD 105
Query: 125 MNYMHQPNLGYVGSCCLAG---IIWKETLHVANLGDSRVVIGTMVNKKIRAEQLTRDHNC 181
M ++ S C A I+ + ++ AN GDSR V+G +K AE L+ DH
Sbjct: 106 NALMQDRDMQEDPSGCTATTALIVDHQVIYCANAGDSRTVLG----RKGTAEPLSFDHKP 161
Query: 182 NDEAIREELRAMHPDDPNVVINDNGSWRVKGFITVSRAIGDAYLKRSEFTLRESFPKLEI 241
N++ + + A D G RV G + +SRAIGD K+ +
Sbjct: 162 NNDVEKARITAAGG------FIDFG--RVNGSLALSRAIGDFEYKKDS----------SL 203
Query: 242 VPEPFTRGVLSAEPEMHTRVLTDNDQFIIFASDGLWDFLSNKKAAEIVQKNPRNGIAKR 300
PE + +++A P++ + +D+F+I A DG+WD S+++ E V R GI R
Sbjct: 204 PPE---KQIVTAFPDVVIHNIDPDDEFLILACDGIWDCKSSQQVVEFV----RRGIVAR 255
>P2CB_BOVIN (O62830) Protein phosphatase 2C beta isoform (EC
3.1.3.16) (PP2C-beta)
Length = 387
Score = 73.6 bits (179), Expect = 9e-13
Identities = 65/237 (27%), Positives = 105/237 (43%), Gaps = 46/237 (19%)
Query: 68 FLGIYDGHGGTQASRFICEHLFKNLLRF----ANDNENDITEATLRNAVSATEEGFL--D 121
F +YDGH G++ + + HL +++ A E ++ N + GFL D
Sbjct: 55 FFAVYDGHAGSRVANYCSTHLLEHITNNEDFRAAGKSGSALEPSVENVKNGIRTGFLKID 114
Query: 122 FAKMNYMHQPN-LGYVGSCCLAGIIWKETLHVANLGDSRVVIGTMVNKKIRAEQL---TR 177
N+ N + GS + +I + ++ N GDSR V+ R+ Q+ T+
Sbjct: 115 EYMRNFSDLRNGMDRSGSTAVGVMISPKHIYFINCGDSRAVL-------YRSGQVCFSTQ 167
Query: 178 DHN-CNDEAIREELRAMHPDDPNVVINDNGS---WRVKGFITVSRAIGDAYLKRSEFTLR 233
DH CN P + + N GS RV G + VSRA+GD K +
Sbjct: 168 DHKPCN------------PREKERIQNAGGSVMIQRVNGSLAVSRALGDYDYKCVD---- 211
Query: 234 ESFPKLEIVPEPFTRGVLSAEPEMHTRVLTDNDQFIIFASDGLWDFLSNKKAAEIVQ 290
+ T ++S EPE++ + + D+FII A DG+WD +SN++ E V+
Sbjct: 212 ---------GKGPTEQLVSPEPEVYEILRAEEDEFIILACDGIWDVMSNEELCEFVK 259
>P2C_PARTE (P49444) Protein phosphatase 2C (EC 3.1.3.16) (PP2C)
Length = 300
Score = 72.8 bits (177), Expect = 2e-12
Identities = 67/254 (26%), Positives = 121/254 (47%), Gaps = 41/254 (16%)
Query: 42 FSSAVVQA-NTTMEDQS--QIEVASNNAVFLGIYDGHGGTQASRFICEHLFKNLLRFAND 98
F+++ +Q TMED + ++ + +VF G++DGHGG + ++F+ +H LL+ N
Sbjct: 24 FAASEMQGWRNTMEDAHIHRHDIIQDVSVF-GVFDGHGGREVAQFVEKHFVDELLKNKNF 82
Query: 99 NENDITEATLRNAVSATEEGFLDFAKMNYMHQ-----PNLGYVGSCCLAGIIWKETLHVA 153
E EA L+ +E L ++Q + Y G +I+K TL+VA
Sbjct: 83 KEQKFEEA-LKETFLKMDELLLTPEGQKELNQYKATDTDESYAGCTANVALIYKNTLYVA 141
Query: 154 NLGDSRVVIGTMVNKKIRAEQLTRDHNCNDEAIREELRAMHPDDPNVVINDNG---SWRV 210
N GDSR V L R++ +D ++ + + +P++ + + G RV
Sbjct: 142 NAGDSRSV-------------LCRNNTNHDMSV--DHKPDNPEEKSRIERAGGFVSDGRV 186
Query: 211 KGFITVSRAIGDAYLKRSEFTLRESFPKLEIVPEPFTRGVLSAEPEMHTRVLTDNDQFII 270
G + +SRA+GD KR LR + ++ A P++ LT D+FI+
Sbjct: 187 NGNLNLSRALGDLEYKRDN-KLRSN------------EQLIIALPDVKKTELTPQDKFIL 233
Query: 271 FASDGLWDFLSNKK 284
DG+++ L++++
Sbjct: 234 MGCDGVFETLNHQE 247
>PDP2_RAT (O88484) [Pyruvate dehydrogenase [Lipoamide]]-phosphatase
2, mitochondrial precursor (EC 3.1.3.43) (PDP 2)
(Pyruvate dehydrogenase phosphatase, catalytic subunit
2) (PDPC 2)
Length = 530
Score = 72.4 bits (176), Expect = 2e-12
Identities = 53/153 (34%), Positives = 74/153 (47%), Gaps = 17/153 (11%)
Query: 150 LHVANLGDSRVVIGTMV-NKKIRAEQLTRDHNCNDEAIREELRAMHPD--DPNVVINDNG 206
LH+AN GD R ++G N LT DHN +EA L+ HP+ D ++I+D
Sbjct: 280 LHIANAGDCRAILGVQGDNGAWSCLPLTCDHNAWNEAELSRLKREHPESEDRTLIIDD-- 337
Query: 207 SWRVKGFITVSRAIGDAYLKRSEFTLRESFPK------LEIV----PEPFTRGVLSAEPE 256
R+ G + RA GD LK S+ R + L I P T L+A+PE
Sbjct: 338 --RLLGVLLPCRAFGDVQLKWSKELQRNVLERGFDTEALNIYQFTPPHYHTPPYLTAKPE 395
Query: 257 MHTRVLTDNDQFIIFASDGLWDFLSNKKAAEIV 289
+ L D+F++ ASDGLWD L N+ +V
Sbjct: 396 VTYHRLRPQDKFLVLASDGLWDMLDNEDVVRLV 428
Score = 34.3 bits (77), Expect = 0.64
Identities = 19/50 (38%), Positives = 29/50 (58%), Gaps = 3/50 (6%)
Query: 42 FSSAVVQANTTMEDQSQIE--VASNNAVFLGIYDGHGGTQASRFICEHLF 89
F S + AN+ +ED+ + V + VF GI+DGHGG ++ + E LF
Sbjct: 110 FESNQLAANSPVEDRQGVASCVQTRGTVF-GIFDGHGGHACAQAVSERLF 158
>P2CB_MOUSE (P36993) Protein phosphatase 2C beta isoform (EC
3.1.3.16) (PP2C-beta) (IA) (Protein phosphatase 1B)
Length = 390
Score = 72.4 bits (176), Expect = 2e-12
Identities = 64/241 (26%), Positives = 106/241 (43%), Gaps = 46/241 (19%)
Query: 64 NNAVFLGIYDGHGGTQASRFICEHLFKNLLRF----ANDNENDITEATLRNAVSATEEGF 119
+N F +YDGH G++ + + HL +++ A D E ++ + + GF
Sbjct: 51 DNWSFFAVYDGHAGSRVANYCSTHLLEHITTNEDFRAADKSGSALEPSVESVKTGIRTGF 110
Query: 120 L--DFAKMNYMHQPN-LGYVGSCCLAGIIWKETLHVANLGDSRVVIGTMVNKKIRAEQL- 175
L D N+ N + GS + ++ ++ N GDSR V+ R Q+
Sbjct: 111 LKIDEYMRNFSDLRNGMDRSGSTAVGVMVSPTHMYFINCGDSRAVL-------CRNGQVC 163
Query: 176 --TRDHN-CNDEAIREELRAMHPDDPNVVINDNGS---WRVKGFITVSRAIGDAYLKRSE 229
T+DH CN P + + N GS RV G + VSRA+GD K +
Sbjct: 164 FSTQDHKPCN------------PVEKERIQNAGGSVMIQRVNGSLAVSRALGDYDYKCVD 211
Query: 230 FTLRESFPKLEIVPEPFTRGVLSAEPEMHTRVLTDNDQFIIFASDGLWDFLSNKKAAEIV 289
+ T ++S EPE++ V + D+F++ A DG+WD +SN++ E V
Sbjct: 212 -------------GKGPTEQLVSPEPEVYEIVRAEEDEFVVLACDGIWDVMSNEELCEFV 258
Query: 290 Q 290
+
Sbjct: 259 K 259
>P2C1_SCHPO (P40371) Protein phosphatase 2C homolog 1 (EC 3.1.3.16)
(PP2C-1)
Length = 347
Score = 72.0 bits (175), Expect = 3e-12
Identities = 72/250 (28%), Positives = 113/250 (44%), Gaps = 56/250 (22%)
Query: 68 FLGIYDGHGGTQASRFICEHLFKNLL-RFANDNENDITEATLRNAVSATEEGFLDFAKMN 126
F+ +YDGH G QAS + ++L K LL + N+ + +T+ V + AK
Sbjct: 104 FVAVYDGHAGIQASDYCQKNLHKVLLEKVRNEPDRLVTDLMDETFVEVNSK----IAKAT 159
Query: 127 YMHQPNLGYVGSCCLAGIIW--------KETLHVANLGDSRVVIGTMVNKKIRAEQLTRD 178
H G C A + + + L+ AN GD+R+V+ + +A +L+ D
Sbjct: 160 --HNDICG-----CTAAVAFFRYEKNRTRRVLYTANAGDARIVLC----RDGKAIRLSYD 208
Query: 179 HNCNDEAIREELRAMHPDDPNVVINDNGSWRVKGFITVSRAIGDAYLKRSEFTLRESFPK 238
H +D E R + +V N R+ G + V+RA+GD YLK
Sbjct: 209 HKGSDA---NESRRVTQLGGLMVQN-----RINGVLAVTRALGDTYLKEL---------- 250
Query: 239 LEIVPEPFTRGVLSAEPEMHTRVLTDNDQFIIFASDGLWDFLSNKKAAEIVQK--NPRNG 296
+ PFT TR+ +D+F I A DGLWD +S+++A + V+ +PR
Sbjct: 251 --VSAHPFTT---------ETRIWNGHDEFFIIACDGLWDVVSDQEAVDFVRNFVSPREA 299
Query: 297 IAKRLLSTAL 306
A RL+ AL
Sbjct: 300 -AVRLVEFAL 308
>P2CB_HUMAN (O75688) Protein phosphatase 2C beta isoform (EC
3.1.3.16) (PP2C-beta)
Length = 479
Score = 71.6 bits (174), Expect = 4e-12
Identities = 65/237 (27%), Positives = 104/237 (43%), Gaps = 46/237 (19%)
Query: 68 FLGIYDGHGGTQASRFICEHLFKNLLRF----ANDNENDITEATLRNAVSATEEGFL--D 121
F +YDGH G++ + + HL +++ A E ++ N + GFL D
Sbjct: 55 FFAVYDGHAGSRVANYCSTHLLEHITTNEDFRAAGKSGSALELSVENVKNGIRTGFLKID 114
Query: 122 FAKMNYMHQPN-LGYVGSCCLAGIIWKETLHVANLGDSRVVIGTMVNKKIRAEQL---TR 177
N+ N + GS + +I + ++ N GDSR V+ R Q+ T+
Sbjct: 115 EYMRNFSDLRNGMDRSGSTAVGVMISPKHIYFINCGDSRAVL-------YRNGQVCFSTQ 167
Query: 178 DHN-CNDEAIREELRAMHPDDPNVVINDNGS---WRVKGFITVSRAIGDAYLKRSEFTLR 233
DH CN P + + N GS RV G + VSRA+GD K +
Sbjct: 168 DHKPCN------------PREKERIQNAGGSVMIQRVNGSLAVSRALGDYDYKCVD---- 211
Query: 234 ESFPKLEIVPEPFTRGVLSAEPEMHTRVLTDNDQFIIFASDGLWDFLSNKKAAEIVQ 290
+ T ++S EPE++ + + D+FII A DG+WD +SN++ E V+
Sbjct: 212 ---------GKGPTEQLVSPEPEVYEILRAEEDEFIILACDGIWDVMSNEELCEYVK 259
>P2CB_RAT (P35815) Protein phosphatase 2C beta isoform (EC 3.1.3.16)
(PP2C-beta) (IA) (Protein phosphatase 1B)
Length = 390
Score = 71.2 bits (173), Expect = 5e-12
Identities = 64/236 (27%), Positives = 103/236 (43%), Gaps = 46/236 (19%)
Query: 68 FLGIYDGHGGTQASRFICEHLFKNLLRF----ANDNENDITEATLRNAVSATEEGFL--D 121
F +YDGH G++ + + HL +++ A D E ++ N + GFL D
Sbjct: 55 FFAVYDGHAGSRVANYCSTHLLEHITTNEDFRAADKSGFALEPSVENVKTGIRTGFLKID 114
Query: 122 FAKMNYMHQPN-LGYVGSCCLAGIIWKETLHVANLGDSRVVIGTMVNKKIRAEQL---TR 177
N+ N + GS + +I ++ N GDSR V+ R Q+ T+
Sbjct: 115 EYMRNFSDLRNGMDRSGSTAVGVMISPTHIYFINCGDSRAVL-------CRNGQVCFSTQ 167
Query: 178 DHN-CNDEAIREELRAMHPDDPNVVINDNGS---WRVKGFITVSRAIGDAYLKRSEFTLR 233
DH CN P + + N GS RV G + VSRA+GD K +
Sbjct: 168 DHKPCN------------PMEKERIQNAGGSVMIQRVNGSLAVSRALGDYDYKCVD---- 211
Query: 234 ESFPKLEIVPEPFTRGVLSAEPEMHTRVLTDNDQFIIFASDGLWDFLSNKKAAEIV 289
+ T ++S EPE++ + + D+F++ A DG+WD +SN++ E V
Sbjct: 212 ---------GKGPTEQLVSPEPEVYEILRAEEDEFVVLACDGIWDVMSNEELCEFV 258
>P2C5_YEAST (Q12511) Protein phosphatase 2C homolog 5 (EC 3.1.3.16)
(PP2C-5)
Length = 572
Score = 70.5 bits (171), Expect = 8e-12
Identities = 76/272 (27%), Positives = 117/272 (42%), Gaps = 49/272 (18%)
Query: 54 EDQSQIEVASNNAVFLGIYDGHGGTQASRFICEHLFKNLLRFAN-------DNENDITEA 106
ED IE + F GI+DGHGG F E L K+L+R+ D + +
Sbjct: 181 EDGKSIE---KDLYFFGIFDGHGGP----FTSEKLSKDLVRYVAYQLGQVYDQNKTVFHS 233
Query: 107 TLRNAV-SATEEGFL---------DFAKMNYMHQPNLGYV--------GSCCLAGII--W 146
+ SA +GFL F K+ PN + GSC L +
Sbjct: 234 DPNQLIDSAISKGFLKLDNDLVIESFRKL--FQDPNNTNIANTLPAISGSCALLSLYNST 291
Query: 147 KETLHVANLGDSRVVIGTMVNK-KIRAEQLTRDHNCNDEAIREELRAMHPDDPNVVINDN 205
L VA GDSR +I + N+ + L+ D ++ +R HP +PNV+ N
Sbjct: 292 NSILKVAVTGDSRALICGLDNEGNWTVKSLSTDQTGDNLDEVRRIRKEHPGEPNVIRNG- 350
Query: 206 GSWRVKGFITVSRAIGDAYLKRSEFTLRESFPKLEIV-------PEPF-TRGVLSAEPEM 257
R+ G + SRA GD K E + E+ P F T ++AEP +
Sbjct: 351 ---RILGSLQPSRAFGDYRYKIKEVDGKPLSDLPEVAKLYFRREPRDFKTPPYVTAEPVI 407
Query: 258 HTRVLTDNDQFIIFASDGLWDFLSNKKAAEIV 289
+ + +N +F++ SDGL++ L+N++ A +V
Sbjct: 408 TSAKIGENTKFMVMGSDGLFELLTNEEIASLV 439
Database: sprot
Posted date: Nov 25, 2004 10:54 AM
Number of letters in database: 59,974,054
Number of sequences in database: 164,201
Lambda K H
0.318 0.133 0.383
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 48,364,215
Number of Sequences: 164201
Number of extensions: 1934645
Number of successful extensions: 4487
Number of sequences better than 10.0: 59
Number of HSP's better than 10.0 without gapping: 43
Number of HSP's successfully gapped in prelim test: 16
Number of HSP's that attempted gapping in prelim test: 4334
Number of HSP's gapped (non-prelim): 81
length of query: 432
length of database: 59,974,054
effective HSP length: 113
effective length of query: 319
effective length of database: 41,419,341
effective search space: 13212769779
effective search space used: 13212769779
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 67 (30.4 bits)
Medicago: description of AC142396.3