BLAST2 result
BLASTP 2.2.2 [Dec-14-2001]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= AC141862.18 + phase: 0
(783 letters)
Database: sprot
164,201 sequences; 59,974,054 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
DSPP_HUMAN (Q9NZW4) Dentin sialophosphoprotein precursor [Contai... 239 2e-62
DSPP_MOUSE (P97399) Dentin sialophosphoprotein precursor (Dentin... 202 3e-51
DSPP_RAT (Q62598) Dentin sialophosphoprotein precursor [Contains... 150 2e-35
GARP_PLAFF (P13816) Glutamic acid-rich protein precursor 134 9e-31
ATRX_PANTR (Q7YQM4) Transcriptional regulator ATRX (X-linked hel... 132 5e-30
DMP1_MOUSE (O55188) Dentin matrix acidic phosphoprotein 1 precur... 129 2e-29
ATRX_PONPY (Q7YQM3) Transcriptional regulator ATRX (X-linked hel... 129 3e-29
ATRX_HUMAN (P46100) Transcriptional regulator ATRX (X-linked hel... 129 3e-29
DMP1_HUMAN (Q13316) Dentin matrix acidic phosphoprotein 1 precur... 128 5e-29
YFI6_YEAST (P43597) Hypothetical 137.7 kDa protein in UGS1-FAB1 ... 128 7e-29
MDN1_YEAST (Q12019) Midasin (MIDAS-containing protein) 126 2e-28
VG48_SHV21 (Q01033) Hypothetical gene 48 protein 124 1e-27
MDN1_HUMAN (Q9NU22) Midasin (MIDAS-containing protein) 124 1e-27
FUTS_DROME (Q9W596) Microtubule-associated protein futsch 124 1e-27
SR40_YEAST (P32583) Suppressor protein SRP40 122 4e-27
PLS_STAAU (P80544) Surface protein precursor (Plasmin-sensitive ... 122 4e-27
IF2P_HUMAN (O60841) Eukaryotic translation initiation factor 5B ... 121 8e-27
MLH_TETTH (P40631) Micronuclear linker histone polyprotein (MIC ... 120 1e-26
RRB1_MOUSE (Q99PL5) Ribosome-binding protein 1 (Ribosome recepto... 120 2e-26
ATRX_CAEEL (Q9U7E0) Transcriptional regulator ATRX homolog (X-li... 119 4e-26
>DSPP_HUMAN (Q9NZW4) Dentin sialophosphoprotein precursor [Contains:
Dentin phosphoprotein (Dentin phosphophoryn) (DPP);
Dentin sialoprotein (DSP)]
Length = 1253
Score = 239 bits (610), Expect = 2e-62
Identities = 128/716 (17%), Positives = 335/716 (45%), Gaps = 27/716 (3%)
Query: 77 DARHKEDEEEADELDNKHDEQTKLDDVNGVEDNSEHKEDSVEQESEESSQNAKTDLEGEQ 136
DA + D + D ++ D+ NG + +DS +S + G
Sbjct: 476 DANSESDNNSSSRGDASYNSDESKDNGNGSDSKGAEDDDSDSTSDTNNSDSNGNGNNGND 535
Query: 137 HTEKVDEENDNAENKENESVEKENEEIKKEVEDTETGESIEEKSHLENEESKETGEISEE 196
+K D +++ +++S + N + D+++ +S + +S + S +
Sbjct: 536 DNDKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNS------SSDSDSSDSDSSD 589
Query: 197 KSHLENEESKETGESSEEKSHLENEESKETGESSEEKSHLENEENKDEEKSKQENEEIKD 256
S ++ +S + +SS+ ++ +S ++ +S + S E++ + + KS + D
Sbjct: 590 SSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSD 649
Query: 257 GEKIQQENEENKDEEKSQQENEENKDEEKSQQENELKKNEGGEKETGEITEEKSKQENEE 316
++ + S + + + S ++ + ++ + ++ + E+ +
Sbjct: 650 SSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSSSSDSSNSSDSSDSSDSSNSSESSD 709
Query: 317 TSETNSKDKEN--EESNQNGSDAKEQVGENHEQDSKQGTEETNGTEGGEKEEHDKIKEDT 374
+S+++ D + + SN N SD+ + + DS ++ +N ++ + + D+
Sbjct: 710 SSDSSDSDSSDSSDSSNSNSSDS-DSSNSSDSSDSSDSSDSSNSSDSSDSSDSSN-SSDS 767
Query: 375 SSDNQVQDGEKNNEAREENYSGDNASSAVVDNKSQESSNKTEEQFDKKEKNEFELESQKN 434
S + D ++ + + N S +++ S+ D+ + S+ + + D + ++ + + +
Sbjct: 768 SDSSDSSDSSDSSNSSDSNDSSNSSDSS--DSSNSSDSSNSSDSSDSSDSSDSDSSNSSD 825
Query: 435 SNETTESTDSTITQNSQGNESEKDQAQTENDTPKGSASESDEQKQEQEQNNTTKDDVQTT 494
S+ +++S+DS+ + +S + D + +++ S++ SD N++ D +
Sbjct: 826 SSNSSDSSDSSNSSDSSDSSDSSDSSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDS 885
Query: 495 DTS--SQNGNDTTEKQNETSEDANSKKEDSSALNTTPNNEDSKSGVAGDQADSTTTTSSS 552
S S N +D+++ N + D++ S + +++ +++ S+S + D ++S+ +++SS
Sbjct: 886 SDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSS 945
Query: 553 ETQDGNTNHGEYKDTTNENPEKNSGQEGTQESGSSSNTFDNKDAASNKVQLTTTSDTSSE 612
++ D + D++N + NSG S SN+ D+ D++++ ++ + S
Sbjct: 946 DSSDSS-------DSSNSSDSSNSGDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSS 998
Query: 613 QKKDESSSAESKSESSQNDNANSGQSNTTSDES----ANDNKDSSQVTTSSENS--AEGN 666
D S+S++S S +D++NS S+ +SD S ++D+ DSS + SS++S ++ +
Sbjct: 999 DSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSS 1058
Query: 667 SNTENNSDENQNDSKNNENTNDSGNTSNDANVNENQNENAAQTKTSENEGDAQNESVESK 726
+++++ + +DS ++ +++DS ++S+ ++ +++ + + + ++ ++S +S
Sbjct: 1059 DSSDSSGSSDSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSS 1118
Query: 727 KENNESAHKDVDNNSNSNDQGSSDTSVTQDDKESRVDLGTLPESNGESHHNDVSSA 782
++ S D N+S+S+D S S D D +S+ S +D S +
Sbjct: 1119 DSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDS 1174
Score = 239 bits (609), Expect = 3e-62
Identities = 136/729 (18%), Positives = 332/729 (44%), Gaps = 31/729 (4%)
Query: 77 DARHKEDEEEADELDNKHDEQTKLDDVNGVEDNSEHKEDSVEQESEESSQNAK-TDLEGE 135
D+ +D+ + N DE DD N DN+ S+ES N +D +G
Sbjct: 451 DSYDFDDKSMQGDDPNSSDESNGNDDANSESDNNSSSRGDASYNSDESKDNGNGSDSKGA 510
Query: 136 QHTEKVDEENDNAENKENESVEKENEEIKKEVEDTETGESIEEKSHLENEESKETGEISE 195
+ D+++D+ + N + + +++G+ + S ++ +S + + S
Sbjct: 511 E-----DDDSDSTSDTNNSDSNGNGNNGNDDNDKSDSGKGKSDSSDSDSSDSSNSSD-SS 564
Query: 196 EKSHLENEESKETGESSEEKSHLENEESKETGESSEEKSHLENEENKDEEKSKQENEEIK 255
+ S ++ +S + +S S + ++ +SS ++ ++ D S ++
Sbjct: 565 DSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKS 624
Query: 256 DGEKIQQENEENKDEEKSQQENEENKDEEKSQQENELKKNEGGEKETGEITEEKSKQENE 315
D K + ++ ++ + S N + + ++ N ++ + ++ S ++
Sbjct: 625 DSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSS 684
Query: 316 ETSETNSKDKENEESNQNGSDAKEQVGENHEQDSKQGTEETNGTEGGEKEEHDKIKEDTS 375
+S++++ ++ S+ + S ++ + DS ++ +N + D+S
Sbjct: 685 SSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSS 744
Query: 376 SDNQVQDGEKNNEAREENYSGDNA----SSAVVDNKSQESSNKTEEQFDKKEKNEFELES 431
+ + ++++ + + S D++ SS D+ + SN + D + + S
Sbjct: 745 DSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSS 804
Query: 432 QKNSNETTESTDSTITQNSQGNESEKDQAQTENDTPKGSASESDEQKQEQEQNNTTKDDV 491
NS+++++S+DS+ + +S ++S +++ S+ SD ++ D
Sbjct: 805 --NSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDSSDSDSSNRSDSS 862
Query: 492 QTTDTS----SQNGNDTTEKQNETSEDANSKKEDSSALNTTPNNEDSKSGVAGDQADSTT 547
++D+S S N +D+++ + + + +S DSS + + +++ S S + D +DS+
Sbjct: 863 NSSDSSDSSDSSNSSDSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSN 922
Query: 548 TTSSSETQDGNTN-----------HGEYKDTTNENPEKNSGQEGTQESGSSSNTFDNKDA 596
++ SSE+ + + N + D++N + NSG S SN+ D+ D+
Sbjct: 923 SSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSGDSSNSSDSSDSNSSDSSDS 982
Query: 597 ASNKVQLTTTSDTSSEQKKDESSSAESKSESSQNDNANSGQSNTTSDES-ANDNKDSSQV 655
+++ ++ + S D S+S++S S +D++NS S+ +SD S ++D+ DSS
Sbjct: 983 SNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSDSSDSSDSSDS 1042
Query: 656 TTSSENSAEGNSNTENNSDEN--QNDSKNNENTNDSGNTSNDANVNENQNENAAQTKTSE 713
+ SS +S +S+ ++S ++ +DS ++ +++DS ++S+ ++ +++ + + + +
Sbjct: 1043 SDSSNSSDSSDSSDSSDSSDSSGSSDSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDS 1102
Query: 714 NEGDAQNESVESKKENNESAHKDVDNNSNSNDQGSSDTSVTQDDKESRVDLGTLPESNGE 773
++ ++S +S ++ S D ++SNS+D S S D D +S+
Sbjct: 1103 SDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDS 1162
Query: 774 SHHNDVSSA 782
S +D S +
Sbjct: 1163 SDSSDSSDS 1171
Score = 239 bits (609), Expect = 3e-62
Identities = 139/713 (19%), Positives = 342/713 (47%), Gaps = 23/713 (3%)
Query: 82 EDEEEADELDNKHDEQTKLDDVNGVEDNSEHKEDSVEQESEESSQNAKTDLEGEQHTEKV 141
+D +++D K D D + NS DS + +S +S+ ++ +D ++
Sbjct: 535 DDNDKSDSGKGKSDSS---DSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSS 591
Query: 142 DEENDNAENKENESVEKENEEIKKEVEDTET-GESIEEKSHLENEESKETGEISEEKSHL 200
D ++ ++ N + S ++ + + +++ +S + +S + +SK S
Sbjct: 592 DSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSS 651
Query: 201 ENEESKETGESSEEKSHLENEESKETGESSEEKSHLENEENKDEEKSKQENEEIKDGEKI 260
+N +S ++ SS ++ +S ++ SS+ S ++ + D S + + +
Sbjct: 652 DNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSS 711
Query: 261 QQENEENKDEEKSQQENEENKDEEKSQQENELKKNEGGEKETGEITEEKSKQENEETSET 320
+ ++ D S N + D S ++ ++ + + + S N S +
Sbjct: 712 DSSDSDSSDSSDSSNSNSSDSDSSNSSDSSD--SSDSSDSSNSSDSSDSSDSSNSSDS-S 768
Query: 321 NSKDKENEESNQNGSDAKEQVGENHEQDSKQGTEETNGTEGGEKEEHDKIKEDTSSDNQ- 379
+S D + + N SD+ + + DS ++ +N ++ + + SSD+
Sbjct: 769 DSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSN 828
Query: 380 VQDGEKNNEAREENYSGDNASSAVVDNKSQESSNKTEEQFDKKEKNEFELESQKN----S 435
D ++ + + + S D++ S+ D+ ++ S+ + + D + + S + S
Sbjct: 829 SSDSSDSSNSSDSSDSSDSSDSSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSSDS 888
Query: 436 NETTESTDSTITQNSQGNESEKDQAQTENDTPKGSASESDEQKQEQEQNNTT-----KDD 490
NE++ S+DS+ + NS ++S D + + + + ++S+S E + +N++ D
Sbjct: 889 NESSNSSDSSDSSNSSDSDSS-DSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDS 947
Query: 491 VQTTDTSSQNGNDTTEKQNETSEDANSKKEDSS-ALNTTPNNEDSKSGVAGDQADSTTTT 549
++D+S+ + + + + +S+ ++S DSS + N++ +++ S S + D +DS+ ++
Sbjct: 948 SDSSDSSNSSDSSNSGDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSS 1007
Query: 550 SSSETQDGNTNHGEYKDTTNENPEKNSGQEGTQESGSSSNTFDNKDAASNKVQLTTTSDT 609
SS++ D + + + + + +S + +S SSN+ D+ D++ + ++ +
Sbjct: 1008 DSSDSSDSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSGSS 1067
Query: 610 SSEQKKDESSSAESKSESSQNDNANSGQSNTTSDES-ANDNKDSSQVTTSSENSAEGNSN 668
S D S S++S S +D+++S +S+ +SD S ++D+ DSS + SS++S +S+
Sbjct: 1068 DSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSS 1127
Query: 669 TENNSDENQNDSKNNENTNDSGNTSNDANVNENQNENAAQTKTSENEGDAQNESVESKKE 728
+NS ++ +DS ++ +++DS ++S+ ++ +++ + + + + ++ ++S +S +
Sbjct: 1128 DSSNSSDS-SDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNES 1186
Query: 729 NNESAHKDVDNNSNSNDQGSSDTSVTQDDKESRVDLGTLPESNGESHHNDVSS 781
++ S D ++SNS+D SSD+S + D D +G ++N S
Sbjct: 1187 SDSSDSSDSSDSSNSSD--SSDSSDSSDSTSDSNDESDSQSKSGNGNNNGSDS 1237
Score = 235 bits (599), Expect = 4e-61
Identities = 131/725 (18%), Positives = 334/725 (46%), Gaps = 24/725 (3%)
Query: 77 DARHKEDEEEADELDNKHDEQT----KLDDVNGVEDNSEHKEDSVEQESEESSQNAKTD- 131
D++ ED++ D + + +D N D+ + K DS + +S +SS ++ +
Sbjct: 506 DSKGAEDDDSDSTSDTNNSDSNGNGNNGNDDNDKSDSGKGKSDSSDSDSSDSSNSSDSSD 565
Query: 132 -LEGEQHTEKVDEENDNAENKENESVEKENEEIKKEVEDTETGESIEEKSHLENEESKET 190
+ + ++D++++ ++S + ++ + + +++ +S + ++ +SK
Sbjct: 566 SSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKS- 624
Query: 191 GEISEEKSHLENEESKETGESSEEKSHLENEESKETGESSEEKSHLENEENKDEEKSKQE 250
KS ++ +S +SS+ S ++ ++ ++ +SS + ++ ++ D S
Sbjct: 625 ---DSSKSESDSSDSDSKSDSSDSNSS-DSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSS 680
Query: 251 NEEIKDGEKIQQENEENKDEEKSQQENEENKDEEKSQQENELKKNEGGEKETGEITEEKS 310
++ + + + + + E+ ++ D S + + ++ S
Sbjct: 681 SDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDS 740
Query: 311 KQENEETSETNSKDKENEESNQNGSDAKEQVGENHEQDSKQGTEETNGTEGGEKEEHDKI 370
++ + +NS D + + N SD+ + + DS ++ + + + +
Sbjct: 741 SDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSN- 799
Query: 371 KEDTSSDNQVQDGEKNNEAREENYSGDNASSAVVDNKSQESSNKTEEQFDKKEKNEFELE 430
D+S+ + D ++++ N S + SS D+ + S+ + + D + +
Sbjct: 800 SSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDSSDSDSSNRS 859
Query: 431 SQKNSNETTESTDSTITQNSQGNESEKDQAQTENDTPKGSASESDEQKQEQEQNNTTKDD 490
NS+++++S+DS+ + +S + D ++ N + +S S + N++ D
Sbjct: 860 DSSNSSDSSDSSDSSNSSDSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSD 919
Query: 491 VQTTDTSSQ--------NGNDTTEKQNETSEDANSKKEDSSALNTTPNNEDSKSGVAGDQ 542
+ SS+ N +D++ + + +S DSS + N+ DS + D
Sbjct: 920 SSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSGDSSNSSDSSDSNSSDS 979
Query: 543 ADSTTTTSSSETQDGNTNHGEYKDTTNENPEKNSGQEGTQESGSSSNTFDNKDAASNKVQ 602
+DS+ ++ SS++ D + + + + + +S + S SSN+ D+ D++ +
Sbjct: 980 SDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSDSSDSSDS 1039
Query: 603 LTTTSDTSSEQKKDESSSAESKSESSQNDNANSGQSNTTSDES-ANDNKDSSQVTTSSEN 661
++ ++S D S S++S S +D+++S S+ +SD S ++D+ DSS + SS++
Sbjct: 1040 SDSSDSSNSSDSSDSSDSSDSSDSSGSSDSSDSSDSSDSSDSSDSSDSSDSSDSSESSDS 1099
Query: 662 SAEGNSNTENNSDE--NQNDSKNNENTNDSGNTSNDANVNENQNENAAQTKTSENEGDAQ 719
S +S+ ++S + + +DS ++ +++DS N+S+ ++ +++ + + + + ++
Sbjct: 1100 SDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDS 1159
Query: 720 NESVESKKENNESAHKDVDNNSNSNDQG-SSDTSVTQDDKESRVDLGTLPESNGESHHND 778
++S +S ++ S D ++S+SN+ SSD+S + D S + S+ S ND
Sbjct: 1160 SDSSDSSDSSDSSDSSDSSDSSDSNESSDSSDSSDSSDSSNSSDSSDSSDSSDSTSDSND 1219
Query: 779 VSSAE 783
S ++
Sbjct: 1220 ESDSQ 1224
Score = 232 bits (592), Expect = 2e-60
Identities = 164/762 (21%), Positives = 355/762 (46%), Gaps = 70/762 (9%)
Query: 82 EDEEEADELDNKHDEQTKLDDVNGVEDNSE----HKEDSVEQESEESSQNAKTDLEGEQH 137
EDEE + D+ ++ + + +G ED+ + DS E E ++ +++G++
Sbjct: 263 EDEEAGNGKDSSNNSKGQEGQDHGKEDDHDSSIGQNSDSKEYYDPEGKEDPHNEVDGDKT 322
Query: 138 TEKVDEENDNAENKEN-----ESVEKENEEIKKEVEDTETGESIEEKSHLENEESKETGE 192
++ EEN ++N E +K N K VE+ T ES ++H + + E
Sbjct: 323 SKS--EENSAGIPEDNGSQRIEDTQKLNHRESKRVENRITKES---ETHAVGKSQDKGIE 377
Query: 193 ISEEKSHLENEESKETGESSEEKSH-------LENEESKETGE--------SSEEKSHLE 237
I S N +KE G+ +E K L K GE E +
Sbjct: 378 IKGPSSGNRNI-TKEVGKGNEGKEDKGQHGMILGKGNVKTQGEVVNIEGPGQKSEPGNKV 436
Query: 238 NEENKDEEKSKQENEEIKDGEKIQQENEENKDEEKSQQENEENKDEEKSQQENELKKNEG 297
N + + + +K Q ++ N +E + ++ ++ + S + N
Sbjct: 437 GHSNTGSDSNSDGYDSYDFDDKSMQGDDPNSSDESNGNDDANSESDNNSSSRGDASYNSD 496
Query: 298 GEKETGEITEEKSKQENEE--TSETNSKDKENEESNQNGSDAKEQVGENHEQDS-KQGTE 354
K+ G ++ K ++++ TS+TN+ D +N N + K G+ S ++
Sbjct: 497 ESKDNGNGSDSKGAEDDDSDSTSDTNNSDSNGNGNNGNDDNDKSDSGKGKSDSSDSDSSD 556
Query: 355 ETNGTEGGEKEEHDKIKEDTSSDNQVQDGEKNNEAREENYSGDNASSAVVDNKSQESSNK 414
+N ++ + + D ++SSD+ D + ++ + ++ N+S + + S +SS+
Sbjct: 557 SSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDS 616
Query: 415 TEEQFDKKEKNEFELESQ----------------------------KNSNETTESTDSTI 446
++ K + ++ E +S NS+++++S+DS+
Sbjct: 617 SDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSD 676
Query: 447 TQNSQGNESEKDQAQTENDTPKGSASESDEQKQEQEQNNTTKDDVQTTDTSSQNGNDTTE 506
+ +S + S D + + + + +S S E + +++ D ++D+S+ N +D+
Sbjct: 677 SSSSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSD--SSDSSNSNSSDSDS 734
Query: 507 KQNETSEDANSKKEDSSALNTTPNNEDSKSGVAGDQADSTTTTSSSETQDGN--TNHGEY 564
+ S D++ + S++ +++ +++ S S + D +DS+ ++ SS + D N +N +
Sbjct: 735 SNSSDSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDS 794
Query: 565 KDTTNENPEKNSGQEGTQESGSSSNTFDNKDAASNKVQLTTTSDTSSEQKKDESSSAESK 624
D++N + NS S S++ ++ D++++ +++ + S D S S++S
Sbjct: 795 SDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDSSDSD 854
Query: 625 SESSQNDNANSGQSNTTSDES-ANDNKDSSQVTTSSENS-AEGNSNTENNSDENQNDSKN 682
S S+++D++NS S+ +SD S ++D+ DSS + S+E+S + +S++ N+SD + +DS N
Sbjct: 855 S-SNRSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSN 913
Query: 683 NENTNDSGNTSNDA-NVNENQNENAAQTKTSENEGDAQNESVESKKENN-ESAHKDVDNN 740
+ +++DS N+S+ + + N + N N++ + S + D+ + S S N+ +S++ ++
Sbjct: 914 SSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSGDSSNSSDSSD 973
Query: 741 SNSNDQGSSDTSVTQDDKESRVDLGTLPESNGESHHNDVSSA 782
SNS+D S S D D +S+ S +D S +
Sbjct: 974 SNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDS 1015
Score = 232 bits (592), Expect = 2e-60
Identities = 125/713 (17%), Positives = 345/713 (47%), Gaps = 16/713 (2%)
Query: 81 KEDEEEADELDNKHD-EQTKLDDVNGVEDNSEHKEDSVEQESEESSQNAKTDLEGEQHTE 139
K D ++D D+ + + + D + + NS DS + +S +SS + +D +
Sbjct: 546 KSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSS 605
Query: 140 KVDEENDNAENKENESVEKENEEIKKEVEDTETGESIEEKSHLE---NEESKETGEISEE 196
+ +D++++ ++ + ++ + + + D+++ + + + N +S ++ S
Sbjct: 606 DSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNS 665
Query: 197 KSHLENEESKETGESSEEKSHLENEESKETGESSEEKSHLENEENKDEEKS-KQENEEIK 255
++ +S ++ SS+ S ++ S ++ +SS+ + E+ ++ D S ++ +
Sbjct: 666 SDSSDSSDSSDSSSSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSS 725
Query: 256 DGEKIQQENEENKDEEKSQQENEENKDEEKSQQENELKKNEGGEKETGEITEEKSKQE-- 313
+ ++ + D S ++ + + S + ++ + + + S
Sbjct: 726 NSNSSDSDSSNSSDSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDS 785
Query: 314 NEETSETNSKDKENEESNQNGSDAKEQVGENHEQDSKQGTEETNGTEGGEKEEHDKIKED 373
N+ ++ ++S D N + N SD+ + ++ + DS ++ +N ++ + D
Sbjct: 786 NDSSNSSDSSDSSNSSDSSNSSDSSDS-SDSSDSDSSNSSDSSNSSDSSDSSNSSD-SSD 843
Query: 374 TSSDNQVQDGEKNNEAREENYSGDNASSAVVDNKSQESSNKTEEQFDKKEKNEFELESQK 433
+S + D + +N + N S + SS D+ + S+ + + D E + S
Sbjct: 844 SSDSSDSSDSDSSNRSDSSNSSDSSDSS---DSSNSSDSSDSSDSSDSNESSNSSDSSDS 900
Query: 434 NSNETTESTDSTITQNSQGNESEKDQAQTENDTPKGSASESDEQKQEQEQNNTTKDDVQT 493
+++ ++S+DS+ + +S + + D +++ N + ++S+S + ++++ +
Sbjct: 901 SNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSS 960
Query: 494 TDTSSQNGNDTTEKQNETSEDANSKKEDSSALNTTPNNEDSKSGVAGDQADSTTTTSSSE 553
S N +D+++ + S D+++ + S + +++ +++ S S + D +DS+ ++ SS
Sbjct: 961 NSGDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSN 1020
Query: 554 TQDGNTNHGEYKDTTNENPEKNSGQEGTQESGSSSNTFDNKDAA--SNKVQLTTTSDTSS 611
+ D + + + + + +S + +S SS++ D+ D++ S+ + +SD+S
Sbjct: 1021 SSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSGSSDSSDSSDSSDSSD 1080
Query: 612 EQKKDESSSAESKSESS-QNDNANSGQSNTTSDESANDNKDSSQVTTSSENSAEGNSNTE 670
+SS + SESS +D+++S S+ +SD S + + S ++ S NS++ + +++
Sbjct: 1081 SSDSSDSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSD 1140
Query: 671 NNSDENQNDSKNNENTNDSGNTSNDANVNENQNENAAQTKTSENEGDAQNESVESKKENN 730
++ + +DS ++ +++DS ++S+ ++ +++ + + + + NE ++S +S +N
Sbjct: 1141 SSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDSSDSSDSSDSSN 1200
Query: 731 ESAHKDVDNNSNSNDQGSSDTSVTQDDKESRVDLGTLPESNGESHHNDVSSAE 783
S D ++S+S S+D S +Q + + G+ +S+ E ++ S+++
Sbjct: 1201 SSDSSDSSDSSDSTSD-SNDESDSQSKSGNGNNNGSDSDSDSEGSDSNHSTSD 1252
Score = 231 bits (590), Expect = 4e-60
Identities = 118/690 (17%), Positives = 317/690 (45%), Gaps = 13/690 (1%)
Query: 77 DARHKEDEEEADELDNKHDEQTKLDDVNGVEDNSEHKEDSVEQESEESSQNAKTDLEGEQ 136
D+ D + +D D+ + D + D+S+ + S +S +SS + + E
Sbjct: 573 DSNSSSDSDSSDS-DSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSES 631
Query: 137 HTEKVDEENDNAENKENESVEK-ENEEIKKEVEDTETGESIEEKSHLENEESKETGEISE 195
+ D ++D++++ ++S + ++ + +++ +S + + +S + + S
Sbjct: 632 DSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSSSSDSSN 691
Query: 196 EKSHLENEESKETGESSEEKSHLENEESKETGESSEEKSHLENEENKDEEKSKQENEEIK 255
++ +S + ESS+ +++ S + S+ S ++ + D S ++
Sbjct: 692 SSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSDSSDSSN 751
Query: 256 DGEKIQQENEENKDEEKSQQENEENKDEEKSQQENELKKNEGGEKETGEITEEKSKQENE 315
+ + N + ++ ++ D S N+ N ++ ++ + ++
Sbjct: 752 SSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSND-SSNSSDSSDSSNSSDSSNSSDSS 810
Query: 316 ETSETNSKDKENEESNQNGSDAKEQVGENHEQDSKQGTEETNGTEGGEKEEHDKIKEDTS 375
++S+++ D N + N SD+ + + DS ++ ++ + + S
Sbjct: 811 DSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDSSDSDSSNRSDSSNSSDSSDS 870
Query: 376 SDNQ-VQDGEKNNEAREENYSGDNASSAVVDNKSQESSNKTEEQFDKKEKNEFELESQKN 434
SD+ D ++++ + N S +++ S+ N S S+ + D + + N
Sbjct: 871 SDSSNSSDSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSS--------N 922
Query: 435 SNETTESTDSTITQNSQGNESEKDQAQTENDTPKGSASESDEQKQEQEQNNTTKDDVQTT 494
S++++ES++S+ NS + + D + + + + +S S + + +++ D +
Sbjct: 923 SSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSGDSSNSSDSSDSNSSDSSDS 982
Query: 495 DTSSQNGNDTTEKQNETSEDANSKKEDSSALNTTPNNEDSKSGVAGDQADSTTTTSSSET 554
SS + + + + S D+++ + S + +++ ++ S S + D +DS+ ++ SS++
Sbjct: 983 SNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSDSSDSSDSSDS 1042
Query: 555 QDGNTNHGEYKDTTNENPEKNSGQEGTQESGSSSNTFDNKDAASNKVQLTTTSDTSSEQK 614
D + + + + + +SG + +S SS++ D+ D++ + ++ + S
Sbjct: 1043 SDSSNSSDSSDSSDSSDSSDSSGSSDSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDS 1102
Query: 615 KDESSSAESKSESSQNDNANSGQSNTTSDES-ANDNKDSSQVTTSSENSAEGNSNTENNS 673
D S S++S S +D+++S S+ +S+ S ++D+ DSS + SS++S +S+ ++S
Sbjct: 1103 SDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDS 1162
Query: 674 DENQNDSKNNENTNDSGNTSNDANVNENQNENAAQTKTSENEGDAQNESVESKKENNESA 733
++ + S ++++++ S ++ ++ + + + + +++ + S + D+ + S + N+ES
Sbjct: 1163 SDSSDSSDSSDSSDSSDSSDSNESSDSSDSSDSSDSSNSSDSSDSSDSSDSTSDSNDESD 1222
Query: 734 HKDVDNNSNSNDQGSSDTSVTQDDKESRVD 763
+ N N+N S S D S D
Sbjct: 1223 SQSKSGNGNNNGSDSDSDSEGSDSNHSTSD 1252
Score = 223 bits (569), Expect = 1e-57
Identities = 158/783 (20%), Positives = 351/783 (44%), Gaps = 54/783 (6%)
Query: 39 GHSREQKASYG---ASTKTGNEVVKLGRKD-----LKPRVEETSVIDARHKEDEEEADEL 90
G +++A G ++ G E G++D + + D KED +E+
Sbjct: 260 GDDEDEEAGNGKDSSNNSKGQEGQDHGKEDDHDSSIGQNSDSKEYYDPEGKEDPH--NEV 317
Query: 91 DNKHDEQTKLDDVNGVEDNSEHKEDSVEQESEESSQNAKTDLEGEQHTEKVDEENDNA-- 148
D +++ + EDN + + ++ + S+ + + E T V + D
Sbjct: 318 DGDKTSKSEENSAGIPEDNGSQRIEDTQKLNHRESKRVENRITKESETHAVGKSQDKGIE 377
Query: 149 ---ENKENESVEKENEEIKKEVEDTETGESIEEKSHLENEESKETGEISEEKSHLENEES 205
+ N ++ KE + + ED I K +++ + E +KS N+
Sbjct: 378 IKGPSSGNRNITKEVGKGNEGKEDKGQHGMILGKGNVKTQGEVVNIEGPGQKSEPGNKVG 437
Query: 206 KETGESSEEKSHLENEESKETGESSEEKSHLENEENKDEEKSKQENEEIKDGEKIQQENE 265
S ++ + + ++ + + D+ S+ +N G+ +E
Sbjct: 438 HSNTGSDSNSDGYDSYDFDDKSMQGDDPNSSDESNGNDDANSESDNNSSSRGDASYNSDE 497
Query: 266 ENKDEEKSQQENEENKDEEKSQQENELKKNEGGEKETGEITEEKSKQENEETSETNSKDK 325
+ S + E+ D + + N N G + + S + ++S+++S D
Sbjct: 498 SKDNGNGSDSKGAEDDDSDSTSDTNNSDSNGNGNNGNDDNDKSDSGKGKSDSSDSDSSDS 557
Query: 326 ENEESNQNGSDA------KEQVGENHEQDSKQGTEETNGTEGGEKEEHDKIKEDTSSDNQ 379
N + + SD+ ++ + DS ++ + + D SSD+
Sbjct: 558 SNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSS 617
Query: 380 VQDGEKNNEAREENYSGDNAS-SAVVDNKSQESSNKTEEQFDKKEKNEFELESQKNSNET 438
K++ ++ E+ S D+ S S D+ S +SS+ ++ N + +S+++
Sbjct: 618 DSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDS 677
Query: 439 TESTDSTITQNSQGNESEKDQAQTEN-----DTPKGSASESDEQKQEQEQNNTTKDDVQT 493
+ S+DS+ + +S + D + + N D+ S S+S + N++ D +
Sbjct: 678 SSSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNS 737
Query: 494 TDTS----------SQNGNDTTEKQNET-SEDANSKKEDSSALNTTPNNEDSKSGVAGDQ 542
+D+S S + +D+++ N + S D++ + S + N++ +N+ S S + D
Sbjct: 738 SDSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDS 797
Query: 543 ADSTTTTSSSETQDGNTNHGEYKDTTNENPEKNSGQEGTQESGSSSNTFDNKDAASNKVQ 602
++S+ +++SS++ D + D+++ + +S + +S SSN+ D+ D++ +
Sbjct: 798 SNSSDSSNSSDSSDSS-------DSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDS--- 847
Query: 603 LTTTSDTSSEQKKDESSSAESKSESSQNDNANSGQSNTTSDESANDN-KDSSQVTTSSEN 661
+ +SD+ S + D S+S++S S +++++S S+ +SD + + N DSS + SS++
Sbjct: 848 -SDSSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSNESSNSSDSSDSSNSSDS 906
Query: 662 SAEGNSNTENNSD-ENQNDSKNNENTNDSGNTSNDANVNE-NQNENAAQTKTSENEGDAQ 719
+ +SN+ ++SD N +DS + N++D+ N+S+ +N ++ + + +++ + S N GD+
Sbjct: 907 DSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSGDSS 966
Query: 720 NESVESKKENNESAHKDVDNNSNSNDQGSSDTSVTQDDKESRVDLGTLPESNGESHHNDV 779
N S S ++N S D N+S+S+D S S D + D +S+ S+ +D
Sbjct: 967 NSSDSS--DSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDS 1024
Query: 780 SSA 782
S++
Sbjct: 1025 SNS 1027
Score = 217 bits (552), Expect = 1e-55
Identities = 121/671 (18%), Positives = 318/671 (47%), Gaps = 22/671 (3%)
Query: 72 ETSVIDARHKEDEEEADELDNKHDEQTKLD--DVNGVEDNSEHKEDSVEQESEESSQNAK 129
++S D+ D + +D N D D D + D+S+ K DS + ES+ S ++K
Sbjct: 581 DSSDSDSSDSSDSDSSDS-SNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSK 639
Query: 130 TDLEGEQHTEKVDE----ENDNAENKENESVEKENEEIKKEVEDTETGESIEEKSHLENE 185
+D ++ D ++ N+ N + S ++ + + + + +S ++
Sbjct: 640 SDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSSSSDSSNSSDSSDSS 699
Query: 186 ESKETGEISEEKSHLENEESKETGESSEEKSHLENEESKETGESSEEKSHLENEENKDEE 245
+S + E S+ +++ S + S+ S ++ S ++ +SS+ + ++ D
Sbjct: 700 DSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSDSSDSSNSSDSSDSS 759
Query: 246 KSKQENEEIKDGEKIQQENEENK----DEEKSQQENEENKDEEKSQQENELKKNEGGEKE 301
S ++ + + N D S ++ + + S + ++ + +
Sbjct: 760 DSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSD 819
Query: 302 TGEITEEKSKQENEETSETNSKDKENEESNQNGSDAKEQVGENHEQDSKQGTEETNGTEG 361
+ ++ + ++ ++S ++ ++ S+ + SD+ + ++ DS ++ +N ++
Sbjct: 820 SSNSSDSSNSSDSSDSSNSSDSSDSSDSSDSSDSDSSNRSDSSNSSDSSDSSDSSNSSDS 879
Query: 362 GEKEEH-DKIKEDTSSDNQVQDGEKNNEAREENYSGDNASSAVVDNKSQESSNKTEEQFD 420
+ + D + SSD+ ++++ + + S D++ S+ + S ESSN ++
Sbjct: 880 SDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSN-SSDSSESSNSSDNSNS 938
Query: 421 KKEKNEFELESQKNSNETTESTDSTITQNSQ--GNESEKDQAQTENDTPKGSASESDEQK 478
N + +S+ +++S++S + NS + + D + + N + +S+S +
Sbjct: 939 SDSSNSSDSSDSSDSSNSSDSSNSGDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSS 998
Query: 479 QEQEQNNTTKDDVQTTDTSSQNGNDTTEKQNET-SEDANSKKEDSSALNTTPNNEDSKSG 537
+ +N++ + + S N +D++ + + S D++ + S + N++ +++ S S
Sbjct: 999 DSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSS 1058
Query: 538 VAGDQADSTTTTSSSETQDGNTNHGEYKDTTNENPEKNSGQEGTQESGSSSNTFDNKDAA 597
+ D + S+ ++ SS++ D + + + + + ++S + +S SS++ D+ D++
Sbjct: 1059 DSSDSSGSSDSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSS 1118
Query: 598 SNKVQLTTTSDTSSEQKKDESSSAESKSESSQNDNANSGQSNTTSDES-ANDNKDSSQVT 656
+ ++ ++S D S S++S S +D+++S S+ +SD S ++D+ DSS +
Sbjct: 1119 DSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSS 1178
Query: 657 TSSEN--SAEGNSNTENNSDENQNDSKNNENTNDSGNTSNDANVNENQN---ENAAQTKT 711
SS++ S++ + +++++ N +DS ++ +++DS + SND + +++++ N
Sbjct: 1179 DSSDSNESSDSSDSSDSSDSSNSSDSSDSSDSSDSTSDSNDESDSQSKSGNGNNNGSDSD 1238
Query: 712 SENEGDAQNES 722
S++EG N S
Sbjct: 1239 SDSEGSDSNHS 1249
Score = 216 bits (549), Expect = 2e-55
Identities = 152/743 (20%), Positives = 351/743 (46%), Gaps = 45/743 (6%)
Query: 77 DARHKED----EEEADELDNKHDEQTKLDDVNGVEDNSEHKEDSVEQESE-ESSQNAKTD 131
DA H ED +E+ ++ ++ D++ +E++ ++ ++ E + S +N +
Sbjct: 169 DAGHNEDVAVVQEDGPQVAGSNNSTDNEDEI--IENSCRNEGNTSEITPQINSKRNGTKE 226
Query: 132 LEGEQHTEKVDEENDNAENKEN-ESVEKENEEIKKEVEDTETGESIEEKSHLENEESKET 190
E T + D DN++ + +++ +E + ED E G + ++ + +E ++
Sbjct: 227 AEVTPGTGE-DAGLDNSDGSPSGNGADEDEDEGSGDDEDEEAGNGKDSSNNSKGQEGQDH 285
Query: 191 GEISEEKSHL-ENEESKE------------------TGESSEEKSHLENEESKETGESSE 231
G+ + S + +N +SKE T +S E + + + + E ++
Sbjct: 286 GKEDDHDSSIGQNSDSKEYYDPEGKEDPHNEVDGDKTSKSEENSAGIPEDNGSQRIEDTQ 345
Query: 232 EKSHLENEENKDEEKSKQENEEI----KDGEKIQQENEENKDEEKSQQENEENKDEEKSQ 287
+ +H E++ ++ + E + G +I+ + N++ K + E K E+K Q
Sbjct: 346 KLNHRESKRVENRITKESETHAVGKSQDKGIEIKGPSSGNRNITKEVGKGNEGK-EDKGQ 404
Query: 288 QENELKKNEGGEKETGEITEEKSKQENEETSETNSKDKENEESNQNGSDAKEQVGENHEQ 347
L K G K GE+ + + E +SN +G D+ + ++ +
Sbjct: 405 HGMILGK--GNVKTQGEVVNIEGPGQKSEPGNKVGHSNTGSDSNSDGYDSYDFDDKSMQG 462
Query: 348 DSKQGTEETNGTEGGEKE-EHDKIKEDTSSDNQVQDGEKNNEAREENYSGDNASSAVVDN 406
D ++E+NG + E +++ +S N + + N + + D++ S N
Sbjct: 463 DDPNSSDESNGNDDANSESDNNSSSRGDASYNSDESKDNGNGSDSKGAEDDDSDSTSDTN 522
Query: 407 KSQESSNKTEEQFDKKEKNEFELESQKNSNETTESTDSTITQNSQGNESEKDQAQTENDT 466
S + N D + + + +S + +++++S++S+ + +S ++S + +++D+
Sbjct: 523 NSDSNGNGNNGNDDNDKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDS 582
Query: 467 PKGSASESDEQKQEQEQNNTTKDDVQTTDTSSQNGNDTTEKQNETSEDANSKKEDSSALN 526
+S+S + N++ D + SS + + + K + + +++S DS + +
Sbjct: 583 SDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDS 642
Query: 527 TTPNNEDSK-SGVAGDQADSTTTTSSSETQDGNTNHGEYKDTTNENPEKNSGQEGTQESG 585
+ N+ DS + + D ++S+ ++ SS++ D + + +++ + +S + +S
Sbjct: 643 SDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSSSSDSSNSSDSSDSSDSS 702
Query: 586 SSSNTFDNKDAASNKVQLTTTSDTSSEQKKDESSSAESKSESSQNDNANSGQSNTTSDES 645
+SS + D+ D++ + ++ S S+ D S+S++S S +D++NS S+ +SD S
Sbjct: 703 NSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSDSSDSSNSSDSSDSSDSS 762
Query: 646 -ANDNKDSSQVTTSSENSAEGNSNTENNSDE-----NQNDSKNNENTNDSGNTSNDANVN 699
++D+ DSS + SS++S +SN +NS + N +DS N+ +++DS ++S+ + N
Sbjct: 763 NSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSN 822
Query: 700 ENQNENAAQTKTSENEGDAQNESVESKKENNESAHKDVDNNSNSNDQGSSDTSVTQDDKE 759
+ + N++ + S N D+ + S S +++S+++ ++SNS+D S S D
Sbjct: 823 SSDSSNSSDSSDSSNSSDSSDSSDSSDSSDSDSSNR--SDSSNSSDSSDSSDSSNSSDSS 880
Query: 760 SRVDLGTLPESNGESHHNDVSSA 782
D ES+ S +D S++
Sbjct: 881 DSSDSSDSNESSNSSDSSDSSNS 903
Score = 110 bits (275), Expect = 1e-23
Identities = 133/650 (20%), Positives = 253/650 (38%), Gaps = 79/650 (12%)
Query: 159 ENEEIKKEVEDTETGESIEEKSHLENEESKETGEISEEKSHLENEESKETGESSEEKSHL 218
+++ +++ VE + + + +E +G I +E L +E + E++++
Sbjct: 20 QSKPLERHVEKSMNLHLLARSNVSVQDELNASGTI-KESGVLVHEGDRGRQENTQDGHKG 78
Query: 219 ENEESKET---GESSEEKSHLENEENKDEEKSKQENEEIKDGEKIQQENEENK------- 268
E SK G+S S L NEE E + + G EEN
Sbjct: 79 EGNGSKWAEVGGKSFSTYSTLANEEGNIEGWNGDTGKAETYGHDGIHGKEENITANGIQG 138
Query: 269 -----DEEKSQQENEENKDEEKSQQENELKKNEGGEKETGEITEEKSKQENEETSETNSK 323
D + + N + +K+ Q ++ + G E + +E Q + T+++
Sbjct: 139 QVSIIDNAGATNRSNTNGNTDKNTQNGDV--GDAGHNEDVAVVQEDGPQVAGSNNSTDNE 196
Query: 324 DKENEESNQNGSDAKEQVGENHEQDSKQGTEETNGTEGGEKEEHDKIKEDTSSDNQVQDG 383
D+ E S +N + E + + + + GT+E T G ED DN DG
Sbjct: 197 DEIIENSCRNEGNTSEITPQINSK--RNGTKEAEVTPG--------TGEDAGLDNS--DG 244
Query: 384 EKNNEAREENY---SGDNASSAVVDNKSQESSNKTEEQFDKKEKNEFELESQKNSNETTE 440
+ +E+ SGD+ + K +++K +E D ++++
Sbjct: 245 SPSGNGADEDEDEGSGDDEDEEAGNGKDSSNNSKGQEGQDHGKEDDH------------- 291
Query: 441 STDSTITQNSQGNE----SEKDQAQTENDTPKGSASESDEQKQEQEQNNTTKDDVQTTDT 496
DS+I QNS E K+ E D K S SE + + D
Sbjct: 292 --DSSIGQNSDSKEYYDPEGKEDPHNEVDGDKTSKSEENSAGIPE-------------DN 336
Query: 497 SSQNGNDTTEKQNETSEDANSKKEDSSALNTTPNNEDSKSGVAGDQADSTTTTSS-SETQ 555
SQ DT + + S+ ++ S + ++D + G + + T +
Sbjct: 337 GSQRIEDTQKLNHRESKRVENRITKESETHAVGKSQDKGIEIKGPSSGNRNITKEVGKGN 396
Query: 556 DGNTNHGEYKDTTNENPEKNSGQEGTQESGSSSNTFDNKDAASNKVQLTTTSDTSSEQKK 615
+G + G++ + K G+ E + NK SN T S+
Sbjct: 397 EGKEDKGQHGMILGKGNVKTQGEVVNIEGPGQKSEPGNKVGHSN---------TGSDSNS 447
Query: 616 DESSSAESKSESSQNDNANSG-QSNTTSDESANDNKDSSQVTTSSENSAEG--NSNTENN 672
D S + +S Q D+ NS +SN D ++ + +SS +S NS E N N ++
Sbjct: 448 DGYDSYDFDDKSMQGDDPNSSDESNGNDDANSESDNNSSSRGDASYNSDESKDNGNGSDS 507
Query: 673 SDENQNDSKNNENTNDSGNTSNDANVNENQNENAAQTKTSENEGDAQNESVESKKENNES 732
+DS + +TN+S + N N N++ N+ + K + D+ + + ++++S
Sbjct: 508 KGAEDDDSDSTSDTNNSDSNGNGNNGNDD-NDKSDSGKGKSDSSDSDSSDSSNSSDSSDS 566
Query: 733 AHKDVDNNSNSNDQGSSDTSVTQDDKESRVDLGTLPESNGESHHNDVSSA 782
+ D ++++S+D SSD+ + D +S+ S +D S +
Sbjct: 567 SDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDS 616
>DSPP_MOUSE (P97399) Dentin sialophosphoprotein precursor (Dentin
matrix protein-3) (DMP-3) [Contains: Dentin
phosphoprotein (Dentin phosphophoryn) (DPP); Dentin
sialoprotein (DSP)]
Length = 934
Score = 202 bits (514), Expect = 3e-51
Identities = 130/712 (18%), Positives = 333/712 (46%), Gaps = 24/712 (3%)
Query: 84 EEEADELDNKHDEQTKLDDVNGVEDNSEHKEDSVEQESEESSQNAKTDLEGEQHTEKVDE 143
E + E+ E LDD +G + +ED + A E T+
Sbjct: 218 ENQGTEVTPSIGEDAGLDDTDGSPSGNGVEEDEDTGSGDGEGAEAGDGRESHDGTKGQGG 277
Query: 144 END--NAENKENESVEKENEEIKKEVEDTETGESIEEKSHLENEESKETGEISEEKSHLE 201
++ N +++ SV E+++ KE E G + + S E ++ + +++K L
Sbjct: 278 QSHGGNTDHRGQSSVSTEDDD-SKEQEGFPNGHNGDNSSEENGVEEGDSTQATQDKEKLS 336
Query: 202 NEESKETGESSEEKSHLENEESKETGESSEEKSHLENEENKDEEKSKQENEEIKDGEKIQ 261
+++++ E + E+ +G+S ++ E ++ +E+ ++ +
Sbjct: 337 PKDTRDA-----EGGIISQSEACPSGKSQDQGIETEGPNKGNKSIITKESGKLSGSKDSN 391
Query: 262 QENEENKDEEKSQQENEENKDE---EKSQQENELKKNEGGEKETG------EITEEKSKQ 312
D+ S ++ E +K + EKS + L + G E +E +
Sbjct: 392 GHQGVELDKRNSPKQGESDKPQGTAEKSAAHSNLGHSRIGSSSNSDGHDSYEFDDESMQG 451
Query: 313 ENEETSETNSKDKENEESNQNGSDAKEQVGENHEQDSKQGTEETNGTEGGEKEEHDKIKE 372
++ ++S+ ++ E++ ++++ +++ + ++ D + + + GE + D
Sbjct: 452 DDPKSSDESNGSDESDTNSESANESGSRGDASYTSDESSDDDNDSDSHAGEDDSSDDSSG 511
Query: 373 DTSSDNQVQDGEKNNEAREENYSGDNASSAVVDNKSQESSNKTEEQFDKKEKNEFELESQ 432
D SD+ DG+ +E ++E+ S D+ +S+ ++KS S + + + +
Sbjct: 512 DGDSDSN-GDGDSESEDKDESDSSDHDNSSDSESKSDSSDSSDDSSDSSDSSDSSDSSDS 570
Query: 433 KNSNETTESTDSTITQNSQGNESEKDQAQTENDTPKGSASESDEQKQEQEQNNTTKDDVQ 492
+S+++++S+DS+ + +S + + + + + +S+S + + ++++
Sbjct: 571 SDSSDSSDSSDSSDSNSSSDSSDSSGSSDSSDSSDTCDSSDSSDSSDSSDSSDSSDSSDS 630
Query: 493 TTDTSSQNGNDTTEKQNETSEDANSKKEDSSALNTTPNNEDSKSGVAGDQADSTTTTSSS 552
+ + S + +D++ + + + S DSS + + ++ DS + D + S+ ++ SS
Sbjct: 631 SDSSDSSDSSDSSSSSDSSDSSSCSDSSDSSDSSDSSDSSDSSDSSSSDSSSSSNSSDSS 690
Query: 553 ETQDGNTNHGEYKDTTNENPEKNSGQEGTQESGSSSNTFDNKDAASNKVQLTTTSDTSSE 612
++ D +++ + + + +SG + +S +SS++ + D++ + ++ + S
Sbjct: 691 DSSDSSSSSDSSDSSDSSDSSDSSGSSDSSDSSASSDSSSSSDSSDSSSSSDSSDSSDSS 750
Query: 613 QKKDESSSAESKSESSQNDNANSGQSNTTSDES-ANDNKDSSQVTTSSENSAEGNSNTEN 671
D S S++S + S +D+++S S+ +SD S ++D+ DSS + SS++S +S+ +
Sbjct: 751 DSSDSSESSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSS 810
Query: 672 NSDENQNDSKNNENTNDSGNTSNDANVNENQNENAAQTKTSENEGDAQNESVESKKENNE 731
NS ++ +DS ++ +++DS ++S+ ++ +++ + + + + ++ ++S +S ++
Sbjct: 811 NSSDS-SDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDS 869
Query: 732 SAHKDVDNNSNSNDQGSSDTSVTQDDKESRVDLGTLPESNGESHHNDVSSAE 783
S D ++SNS+D SD+ + D G NG S N S+++
Sbjct: 870 SDSSDSSDSSNSSDSSDSDSKDSSSDSSD----GDSKSGNGNSDSNSDSNSD 917
Score = 201 bits (512), Expect = 5e-51
Identities = 129/693 (18%), Positives = 326/693 (46%), Gaps = 27/693 (3%)
Query: 93 KHDEQTKLDDVNGVEDNSEHKEDSVEQESEESSQNAKTDLEGEQHTEKVDEENDNAENKE 152
+ DE T D G E + + S TD G+ D+++ E
Sbjct: 247 EEDEDTGSGDGEGAEAGDGRESHDGTKGQGGQSHGGNTDHRGQSSVSTEDDDSKEQEGFP 306
Query: 153 NESVEKENEEIKKEVEDTETGESIEEKSHLENEESKET-GEISEEKSHLENEESKETGES 211
N +N + VE+ ++ ++ ++K L +++++ G I + + +S++ G
Sbjct: 307 NGH-NGDNSSEENGVEEGDSTQATQDKEKLSPKDTRDAEGGIISQSEACPSGKSQDQGIE 365
Query: 212 SE-----EKSHLENEESKETGESSEEKSHLENEENKDEEKSKQENEEIKDGEKIQQENEE 266
+E KS + E K +G S + H E +K + E+++ + + +
Sbjct: 366 TEGPNKGNKSIITKESGKLSG-SKDSNGHQGVELDKRNSPKQGESDKPQGTAEKSAAHSN 424
Query: 267 NKDEEKSQQENEENKD----EEKSQQENELKKNEGGEKETGEITEEKSKQENEETSETNS 322
N + D +++S Q ++ K ++ E + ++ S+ NE S ++
Sbjct: 425 LGHSRIGSSSNSDGHDSYEFDDESMQGDDPKSSD--ESNGSDESDTNSESANESGSRGDA 482
Query: 323 KDKENEESNQNGSDAKEQVGENHEQDSKQGTEETNGTEGGEKEEHDKIKEDTSSDNQVQD 382
++ES+ + +D+ GE+ D G +++ G+ E DK + D+S + D
Sbjct: 483 S-YTSDESSDDDNDSDSHAGEDDSSDDSSGDGDSDSNGDGDSESEDKDESDSSDHDNSSD 541
Query: 383 GEKNNEAREENYSGDNASSAVVDNKSQESSNKTEEQFDKKEKNEFELESQKNSNETTEST 442
E +++ + + ++S + + S +SS+ ++ + +S+ +++S+
Sbjct: 542 SESKSDSSDSSDDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNSSSDSSDSSGSSDSS 601
Query: 443 DSTITQNSQGNESEKDQAQTENDTPKGSASESDEQKQEQEQNNTTKDDVQTTDTSSQNGN 502
DS+ T +S + D + + + + +S+S + + ++++ ++ + S + +
Sbjct: 602 DSSDTCDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSSSSDSSDSSSCSDSSDSS 661
Query: 503 DTTEKQNETSEDANSKKEDSSALNTTPNNEDSKSGVAGDQADSTTTTSSSETQDGNTNHG 562
D+++ + + +S + SS+ N++ +++ S S + D +DS+ ++ SS++ + +
Sbjct: 662 DSSDSSDSSDSSDSSSSDSSSSSNSSDSSDSSDSSSSSDSSDSSDSSDSSDSSGSSDSSD 721
Query: 563 EYKDTTNENPEKNSGQEGTQESGSSSNTFDNKDAASNKVQLTTTSDTSSEQKKDESSSAE 622
+ + + +S + +S SS++ D+ D++ + ++ + S D S S++
Sbjct: 722 SSASSDSSSSSDSSDSSSSSDSSDSSDSSDSSDSSESSDSSNSSDSSDSSDSSDSSDSSD 781
Query: 623 SKSESSQNDNANSGQSNTTSDES-------ANDNKDSSQVTTSSENSAEGNSNTENNSDE 675
S S +D++NS S+ +SD S ++D+ DSS + SS++S +S+ ++S +
Sbjct: 782 SSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSD 841
Query: 676 -----NQNDSKNNENTNDSGNTSNDANVNENQNENAAQTKTSENEGDAQNESVESKKENN 730
+ +DS ++ +++DS ++S+ ++ +++ + + + + ++ D+++ S +S ++
Sbjct: 842 SSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSDSKDSSSDSSDGDS 901
Query: 731 ESAHKDVDNNSNSNDQGSSDTSVTQDDKESRVD 763
+S + + D+NS+SN SD+ + + + D
Sbjct: 902 KSGNGNSDSNSDSNSDSDSDSEGSDSNHSTSDD 934
Score = 199 bits (507), Expect = 2e-50
Identities = 154/767 (20%), Positives = 340/767 (44%), Gaps = 51/767 (6%)
Query: 55 GNEVVKLGRKDLKPR---VEETSVIDARHKEDEEEADELDNKHDEQTKLDDVN---GVED 108
G+E + +G KD + V E H + E + + E + + + G+ +
Sbjct: 85 GSESIHVGGKDFPTQPILVNEQGNTAEEHNDIETYGHDGVHARGENSTANGIRSQVGIVE 144
Query: 109 NSEHKEDSVEQESEESSQNAKTDLEGEQHTEKVDEEND-------NAENKE--------- 152
N+E E SV ++ +++++ + + +EN+ N+ N E
Sbjct: 145 NAEEAESSVHGQAGQNTKSGGASDVSQNGDATLVQENEPPEASIKNSTNHEAGIHGSGVA 204
Query: 153 NESVEKENEEIKKEVEDTETGESIEEKSHLENEESKETGEISEEKSHLENEESKETGESS 212
+ E + E + TE SI E + L++ + +G EE + + GE +
Sbjct: 205 THETTPQREGLGSENQGTEVTPSIGEDAGLDDTDGSPSGNGVEE----DEDTGSGDGEGA 260
Query: 213 EEKSHLENEESKETGESSEEKSHLENEENKDEEKSKQENEEIKDGEKIQQENEENKDEEK 272
E + ES + + +SH N +++ + E+++ K+ E N N D
Sbjct: 261 EAG---DGRESHDGTKGQGGQSHGGNTDHRGQSSVSTEDDDSKEQEGF--PNGHNGDNSS 315
Query: 273 SQQENEENKDEEKSQQENELKKNEGGEKETGEITEE------KSKQENEETSETNSKDK- 325
+ EE + +Q + +L + + E G I++ KS+ + ET N +K
Sbjct: 316 EENGVEEGDSTQATQDKEKLSPKDTRDAEGGIISQSEACPSGKSQDQGIETEGPNKGNKS 375
Query: 326 -----ENEESNQNGSDAKEQVGENHEQDSKQGTEETNGTEGGEKEEHDKIKEDTSSDNQV 380
+ S S+ + V + KQG + + H + +
Sbjct: 376 IITKESGKLSGSKDSNGHQGVELDKRNSPKQGESDKPQGTAEKSAAHSNLGHSRIGSSSN 435
Query: 381 QDGEKNNEAREENYSGDNASSAVVDNKSQESSNKTEEQFDKKEKNEFELESQKNSNETTE 440
DG + E +E+ GD+ S+ N S ES +E + + + S ++S++ +
Sbjct: 436 SDGHDSYEFDDESMQGDDPKSSDESNGSDESDTNSESANESGSRGDASYTSDESSDDDND 495
Query: 441 STDSTITQNSQGNESEKDQAQTENDTPKGSASESDEQKQEQEQNN----TTKDDVQTTDT 496
S DS ++ ++S D N + + DE N+ + D ++D
Sbjct: 496 S-DSHAGEDDSSDDSSGDGDSDSNGDGDSESEDKDESDSSDHDNSSDSESKSDSSDSSDD 554
Query: 497 SSQNGNDTTEKQNETSEDANSKKEDSSALNTTPNNEDSKSGVAGDQADSTTTTSSSETQD 556
SS + + + + S D++ + S + ++ +++ S S + D +DS+ T SS++ D
Sbjct: 555 SSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNSSSDSSDSSGSSDSSDSSDTCDSSDSSD 614
Query: 557 GNTNHGEYKDTTNENPEKNSGQEGTQESGSSSNTFDNKDAASNKVQLTTTSDTSSEQKKD 616
+++ + D+++ + +S SSS+ + + S+ + +SD+S
Sbjct: 615 -SSDSSDSSDSSDSSDSSDSSDSSDSSDSSSSSDSSDSSSCSDSSDSSDSSDSSDSSDSS 673
Query: 617 ESSSAESKSESSQNDNANSGQSNTTSDESANDNKDSSQVTTSSENSAEGNSNTENNSDEN 676
+SSS++S S S+ +D+++S S+++SD S + + S ++ S +S++ +++++++S +
Sbjct: 674 DSSSSDSSSSSNSSDSSDSSDSSSSSDSSDSSDSSDSSDSSGSSDSSDSSASSDSSSSSD 733
Query: 677 QNDSKNNENTNDSGNTSNDANVNE-NQNENAAQTKTSENEGDAQNESVESKKENNESAHK 735
+DS ++ +++DS ++S+ ++ +E + + N++ + S + D+ + S S ++ +
Sbjct: 734 SSDSSSSSDSSDSSDSSDSSDSSESSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSN 793
Query: 736 DVDNNSNSNDQGSSDTSVTQDDKESRVDLGTLPESNGESHHNDVSSA 782
D++ +S+ SSD+S + D +S D +S+ S +D S +
Sbjct: 794 SSDSSDSSDSSDSSDSSNSSDSSDSS-DSSDSSDSSDSSDSSDSSDS 839
Score = 142 bits (357), Expect = 4e-33
Identities = 88/537 (16%), Positives = 242/537 (44%), Gaps = 49/537 (9%)
Query: 83 DEEEADELDNKHDEQTKLDDVNGVEDNSEHKEDSVEQESE-----ESSQNAKTDLEGEQH 137
D E D+ + D+ D+ NG +++ + E + E S S +++ D + + H
Sbjct: 440 DSYEFDDESMQGDDPKSSDESNGSDESDTNSESANESGSRGDASYTSDESSDDDNDSDSH 499
Query: 138 TEKVDEENDNAENKENESVEKENEEIKKEVEDTETGESIEEKSHLENEESKETGEISEEK 197
+ D +D++ + +++S N + E ED + +S + + ++E ++ + S++
Sbjct: 500 AGEDDSSDDSSGDGDSDS----NGDGDSESEDKDESDSSDHDNSSDSESKSDSSDSSDDS 555
Query: 198 SHLENEESKETGESSEEKSHLENEESKETGESSEEKSHLENEENKDEEKSKQENEEIKDG 257
S +S ++ +SS+ ++ +S ++ +SS+ S ++ ++ S ++
Sbjct: 556 S-----DSSDSSDSSDSSDSSDSSDSSDSSDSSDSNSSSDSSDSSGSSDSSDSSDTCDSS 610
Query: 258 EKIQQENEENKDEEKSQQENEENKDEEKSQQENELKKNEGGEK--ETGEITEEKSKQENE 315
+ + + + ++ ++ D S + + ++ + ++ ++
Sbjct: 611 DSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSSSSDSSDSSSCSDSSDSSDSSDSSDSS 670
Query: 316 ETSETNSKDKENEESNQNGSDAKEQVGENHEQDSKQGTEETNGTEGGEKEEHDKIKEDTS 375
++S+++S D + ++ + SD+ + + DS ++ ++ + G D+S
Sbjct: 671 DSSDSSSSDSSSSSNSSDSSDSSDSSSSSDSSDSSDSSDSSDSS-GSSDSSDSSASSDSS 729
Query: 376 SDNQVQDGEKNNEAREENYSGDNASSAVVDNKSQESSNKTEEQFDKKEKNEFELESQKNS 435
S + D ++++ + + S D++ S+ +S +SSN ++ D + ++ +S
Sbjct: 730 SSSDSSDSSSSSDSSDSSDSSDSSDSS----ESSDSSNSSDSS-DSSDSSD-----SSDS 779
Query: 436 NETTESTDSTITQNSQGNESEKDQAQTENDTPKGSASESDEQKQEQEQNNTTKDDVQTTD 495
+++++S+DS+ + NS + D + + + + +S+S + + ++++ +
Sbjct: 780 SDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDS 839
Query: 496 TSSQNGNDTTEKQNETSEDANSKKEDSSALNTTPNNEDSKSGVAGDQADSTTTTSSSETQ 555
+ S + +D+++ + + +S DSS +++ +++ S S + D +DS + SSS++
Sbjct: 840 SDSSDSSDSSDSSDSSDSSDSSDSSDSS--DSSDSSDSSDSSNSSDSSDSDSKDSSSDSS 897
Query: 556 DGNTNHGEYKDTTNENPEKNSGQEGTQESGSSSNTFDNKDAASNKVQLTTTSDTSSE 612
DG++ G S SN+ N D+ S+ + TS +
Sbjct: 898 DGDSKSGN--------------------GNSDSNSDSNSDSDSDSEGSDSNHSTSDD 934
Score = 139 bits (351), Expect = 2e-32
Identities = 89/551 (16%), Positives = 245/551 (44%), Gaps = 43/551 (7%)
Query: 60 KLGRKDLKPRVEETSVIDARHKEDEEEADELDNKHDEQTKLDDVNGVEDNSEHKEDSVEQ 119
K G D E S + + + HD D+ +D E +
Sbjct: 405 KQGESDKPQGTAEKSAAHSNLGHSRIGSSSNSDGHDSYEFDDESMQGDDPKSSDESNGSD 464
Query: 120 ESEESSQNAK-----------------TDLEGEQHTEKVDEENDNAENKENESVEKENEE 162
ES+ +S++A D + + H + D +D++ + +++S N +
Sbjct: 465 ESDTNSESANESGSRGDASYTSDESSDDDNDSDSHAGEDDSSDDSSGDGDSDS----NGD 520
Query: 163 IKKEVEDTETGESIEEKSHLENEESKETGEISEEKSHLENEESKETGESSEEKSHLENEE 222
E ED + +S + + ++E ++ + S++ S +S ++ +SS+ ++ +
Sbjct: 521 GDSESEDKDESDSSDHDNSSDSESKSDSSDSSDDSS-----DSSDSSDSSDSSDSSDSSD 575
Query: 223 SKETGESSEEKSHLENEENKDEEKSKQENEEIKDGEKIQQENEENKDEEKSQQENEENKD 282
S ++ +SS+ S ++ ++ S ++ + + + + ++ ++ D
Sbjct: 576 SSDSSDSSDSNSSSDSSDSSGSSDSSDSSDTCDSSDSSDSSDSSDSSDSSDSSDSSDSSD 635
Query: 283 EEKSQQENELKKNEGGE--KETGEITEEKSKQENEETSETNSKDKENEESNQNGSDAKEQ 340
S + + ++ + ++ ++ ++S+++S D + ++ + SD+ +
Sbjct: 636 SSDSSDSSSSSDSSDSSSCSDSSDSSDSSDSSDSSDSSDSSSSDSSSSSNSSDSSDSSDS 695
Query: 341 VGENHEQDSKQGTEETNGTEGGEKEEHDKIKEDTSSDNQVQDGEKNNEAREENYSGDNAS 400
+ DS ++ ++ + G D+SS + D ++++ + + S D++
Sbjct: 696 SSSSDSSDSSDSSDSSD-SSGSSDSSDSSASSDSSSSSDSSDSSSSSDSSDSSDSSDSSD 754
Query: 401 SAVVDNKSQESSNKTEEQFDKKEKNEFELESQKNSNETTESTDSTITQNSQGNESEKDQA 460
S ++S +SSN ++ D + ++ +S+++++S+DS+ + NS + D +
Sbjct: 755 S----SESSDSSNSSDSS-DSSDSSD-----SSDSSDSSDSSDSSDSSNSSDSSDSSDSS 804
Query: 461 QTENDTPKGSASESDEQKQEQEQNNTTKDDVQTTDTSSQNGNDTTEKQNETSEDANSKKE 520
+ + + +S+S + + ++++ + + S + +D+++ + S D++ +
Sbjct: 805 DSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSD--SSDSSDSSD 862
Query: 521 DSSALNTTPNNEDSKSGVAGDQADSTTTTSSSETQDGNTNHGEYKDTTN--ENPEKNSGQ 578
S + +++ +++ S S + D +DS + SSS++ DG++ G +N N + +S
Sbjct: 863 SSDSSDSSDSSDSSDSSNSSDSSDSDSKDSSSDSSDGDSKSGNGNSDSNSDSNSDSDSDS 922
Query: 579 EGTQESGSSSN 589
EG+ + S+S+
Sbjct: 923 EGSDSNHSTSD 933
Score = 135 bits (340), Expect = 4e-31
Identities = 86/527 (16%), Positives = 241/527 (45%), Gaps = 29/527 (5%)
Query: 38 IGHSREQKASYGASTKTGNEVVKLGRKDLK---PRVEETSVIDARHKEDEEEADELDNKH 94
+GHSR +S G++ + + ++ P+ + S + E A+E ++
Sbjct: 425 LGHSRIGSSS----NSDGHDSYEFDDESMQGDDPKSSDESNGSDESDTNSESANESGSRG 480
Query: 95 DEQTKLDDVNGVEDNSEHKEDSVEQESEESSQNAKTDLEGEQHTEKVDEENDNAENKENE 154
D D+ + +DN + S++SS + +D G+ +E D++ ++ + +N
Sbjct: 481 DASYTSDESSD-DDNDSDSHAGEDDSSDDSSGDGDSDSNGDGDSESEDKDESDSSDHDNS 539
Query: 155 SVEKENEEIKKEVEDTETGESIEEKSHLENEESKETGEISEEKSHLENEESKETGESSEE 214
S + E K + D+ + +S + ++ +S ++ + S+ ++ +S + +SS+
Sbjct: 540 S----DSESKSDSSDS-SDDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNSSSDSSDS 594
Query: 215 KSHLENEESKETGESSEEKSHLENEENKDEEKSKQENEEIKDGEKIQQENEENKDEEKSQ 274
++ +S +T +SS+ ++ ++ D S ++ + + + + S
Sbjct: 595 SGSSDSSDSSDTCDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSSSSDSSDSSSC 654
Query: 275 QENEENKDEEKSQQENELKKNEGGEKETGEITEEKSKQENEETSETNSKDKENEESNQNG 334
++ ++ D S ++ + + + + + ++ ++S+++S ++ S+
Sbjct: 655 SDSSDSSDSSDSSDSSD-----SSDSSSSDSSSSSNSSDSSDSSDSSSSSDSSDSSDS-- 707
Query: 335 SDAKEQVGENHEQDSKQGTEETNGTEGGEKEEHDKIKEDTSSDNQVQDGEKNNEAREENY 394
SD+ + G + DS ++ ++ ++ + D+S + D ++E+ + +
Sbjct: 708 SDSSDSSGSSDSSDSSASSDSSSSSDSSDSSS----SSDSSDSSDSSDSSDSSESSDSSN 763
Query: 395 SGDNASSAVVDNKSQESSNKTEEQFDKKEKNEFELESQKNSNETTESTDSTITQNSQGNE 454
S D++ S+ + S +SS+ ++ N + +S+++++S++S+ + +S +
Sbjct: 764 SSDSSDSSD-SSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSDSS 822
Query: 455 SEKDQAQTENDTPKGSASESDEQKQEQEQNNTTKDDVQTTDTSSQNGNDTTEKQNETSED 514
D + + + + +S+S + + ++++ D ++D+S + + + +++S
Sbjct: 823 DSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSS-DSSDSSDSSDSSDSSDSSDSSDSSNS 881
Query: 515 ANSKKEDSSALNTTPNNEDSKSGVAGDQADSTTTTSS---SETQDGN 558
++S DS ++ ++ DSKSG ++S + + S SE D N
Sbjct: 882 SDSSDSDSKDSSSDSSDGDSKSGNGNSDSNSDSNSDSDSDSEGSDSN 928
Score = 124 bits (310), Expect = 1e-27
Identities = 66/450 (14%), Positives = 203/450 (44%), Gaps = 43/450 (9%)
Query: 82 EDEEEADELDNKHDEQTKLDDVNGVEDNSEHKEDSVEQESEESSQNAKTDLEGEQHTEKV 141
+DE ++ + DN D ++K D + +D+S+ + S +S +SS ++
Sbjct: 528 KDESDSSDHDNSSDSESKSDSSDSSDDSSDSSDSSDSSDSSDSSDSS------------- 574
Query: 142 DEENDNAENKENESVEKENEEIKKEVEDTETGESIEEKSHLENEESKETGEISEEKSHLE 201
+ +D++++ ++ S +++ +S ++ ++ ++ + S+ +
Sbjct: 575 -DSSDSSDSSDSNS-------------SSDSSDSSGSSDSSDSSDTCDSSDSSDSSDSSD 620
Query: 202 NEESKETGESSEEKSHLENEESKETGESSEEKSHLENEENKDEEKSKQENEEIKDGEKIQ 261
+ +S ++ +SS+ ++ +S + +SS+ S ++ ++ D S ++ + D
Sbjct: 621 SSDSSDSSDSSDSSDSSDSSDSSSSSDSSDSSSCSDSSDSSDSSDS-SDSSDSSDSSSSD 679
Query: 262 QENEENKDEEKSQQENEENKDEEKSQQENELKKNEGGEKETGEITEEKSKQENEETSETN 321
+ N + ++ + D S ++ + G + S ++ + ++
Sbjct: 680 SSSSSNSSDSSDSSDSSSSSDSSDSSDSSDSSDSSGSSDSSDSSASSDSSSSSDSSDSSS 739
Query: 322 SKDKENEESNQNGSDAKEQVGENHEQDSKQGTEETNGTEGGEKEEHDKIKEDTSSDNQVQ 381
S D + + + SD+ E ++ DS ++ ++ ++ + + D+S+ +
Sbjct: 740 SSDSSDSSDSSDSSDSSESSDSSNSSDSSDSSDSSDSSDSSDSSDSSD-SSDSSNSSDSS 798
Query: 382 DGEKNNEAREENYSGDNASSAVVDNKSQESSNKTEEQFDKKEKNEFELESQKNSNETTES 441
D ++++ + + S D++ S + S +SS+ ++ + + +S+++++S
Sbjct: 799 DSSDSSDSSDSSNSSDSSDS----SDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDS 854
Query: 442 TDSTITQNSQGNESEKDQAQTENDTPKGSASESDEQKQEQEQNNTTKDDVQTTDTSSQNG 501
+DS+ + +S + D + + + + +S+SD + + ++D S++G
Sbjct: 855 SDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSDSKDSSSD----------SSDGDSKSG 904
Query: 502 NDTTEKQNETSEDANSKKEDSSALNTTPNN 531
N ++ ++++ D++S E S + ++T ++
Sbjct: 905 NGNSDSNSDSNSDSDSDSEGSDSNHSTSDD 934
Score = 43.5 bits (101), Expect = 0.002
Identities = 45/216 (20%), Positives = 84/216 (38%), Gaps = 12/216 (5%)
Query: 545 STTTTSSSETQDGNTNHGEYKDTTNENPEKNSGQEGTQESGSSSNTFDNKDAASNKVQLT 604
++TT++S+++ DG+ GE +E+ K G +GS S KD + + +
Sbjct: 54 NSTTSNSNDSPDGS-EIGE--QVLSEDGYKRDG------NGSESIHVGGKDFPTQPILVN 104
Query: 605 TTSDTSSEQKKDESSSAESKSESSQNDNANSGQSNTTSDESANDNKDSSQVTTSSENSAE 664
+T+ E E+ + +N AN +S E+A + + S +
Sbjct: 105 EQGNTAEEHNDIETYGHDGVHARGENSTANGIRSQVGIVENAEEAESSVHGQAGQNTKSG 164
Query: 665 GNSNTENNSDENQNDSKNNENTNDSGNTSNDANVNENQNENAAQTKTSENEG-DAQNESV 723
G S+ N D + +T+++A + + + A T + EG ++N+
Sbjct: 165 GASDVSQNGDATLVQENEPPEASIKNSTNHEAGI--HGSGVATHETTPQREGLGSENQGT 222
Query: 724 ESKKENNESAHKDVDNNSNSNDQGSSDTSVTQDDKE 759
E E A D + S S + D D E
Sbjct: 223 EVTPSIGEDAGLDDTDGSPSGNGVEEDEDTGSGDGE 258
>DSPP_RAT (Q62598) Dentin sialophosphoprotein precursor [Contains:
Dentin phosphoprotein (Dentin phosphophoryn) (DPP);
Dentin sialoprotein (DSP)]
Length = 687
Score = 150 bits (378), Expect = 2e-35
Identities = 143/617 (23%), Positives = 266/617 (42%), Gaps = 62/617 (10%)
Query: 165 KEVEDTETGESIEEKSHLENEESKETGEISEEKSHLENEESKETGESSEEKSHLENEESK 224
KE ED ET + H E S G I + EN E E+ E K H + +
Sbjct: 109 KEREDVETYG--HDGIHAGGENSTANG-IRGQVGIAENAE-----EAKESKVHGQPHQDT 160
Query: 225 ETGESSEEKSHLENEENKDEEKSKQENEEIKDGEKIQQENEENKDEEKSQQENEENKDEE 284
+TG +S+ + + QENE G K + E +
Sbjct: 161 KTGLASDTSQN-------GDATLVQENEPQVAGSK-----------NSTNHEVGTHGSGV 202
Query: 285 KSQQENELKKNEGGEKETGEITEEKSKQENEETSETNSKDKENEESNQNGSDAKEQVGEN 344
+Q+ ++ EG E + E+T + + +E + EE GS G+
Sbjct: 203 AAQETTPQREGEGSENQGAEVTPSIGEGAGLDNTEGSPSGNGIEEDEDTGS------GDG 256
Query: 345 HEQDSKQGTEETNGTEG--GEKEEHDKIKEDTSSDNQVQDGEKNNEAREENYSGDNASSA 402
D+ G E +GTEG G+ + S + D K E GDN SS+
Sbjct: 257 VGADAGDGRESHDGTEGHEGQSSGGNNDNRGQGSVSTEDDDSKEQEGSPNGRGGDNTSSS 316
Query: 403 VVDNKSQESSNKTEEQFDKKEKNEFELESQKNSNETTES------TDSTITQNSQGNESE 456
+ +T + E + SQ + + +S T+ + T N E
Sbjct: 317 EETGIEEGDGTQTTQDNQNLSPTEGGIISQAEACPSGQSQNQGLETEGSSTGNKSSITKE 376
Query: 457 KDQAQTENDTPKGSASESDEQKQ-EQEQNNTTKDDVQTTDTSSQNGNDTTEKQNETSEDA 515
+ D+ E D++ +Q +++ + + +DT + G+ + +
Sbjct: 377 SGKLSGSKDSNGHHGMELDKRNSPKQGESDKPQGAAEKSDTHNNMGHSRIGSSSNSDGHD 436
Query: 516 NSKKEDSSALNTTPNNEDSKSGVAGDQADSTTTTSSSETQDGNTNHGEYKDTTNENPEKN 575
+ +D S PN+ D +G D +D + S+ E N NHG+ T++E+ +
Sbjct: 437 SYDFDDESMQGDDPNSSDESNG--SDGSDDANSESAIE----NGNHGDASYTSDESSDNG 490
Query: 576 SGQEG-TQESGSSSNTFDNKDAASNKVQLTTTSDT--SSEQKKDESSSAESKSESSQNDN 632
S + E SS +T D D+ SN + + D S D S +ESKS+SS +D+
Sbjct: 491 SDSDSHAGEDDSSDDTSDTDDSDSNGDDDSESKDKDESDNSNHDNDSDSESKSDSSDSDS 550
Query: 633 --ANSGQSNTTSDES-ANDNKDSSQVTTSSENS----AEGNSNTENNSDENQNDSKNNEN 685
++S S+ +SD S +D+ DSS + SS++S + +S+T ++SD + DS + ++
Sbjct: 551 DSSDSSDSSDSSDSSETSDSSDSSDTSDSSDSSDSSDSSNSSDTSDSSDSSDGDSSDGDS 610
Query: 686 TNDSGNTSNDANVNENQNENAAQTK---TSENEGDAQNESVESKKENNES--AHKDVDNN 740
++ + S+ +N +++ + +++ + +S+++ D+++ + +S +N++S + D D++
Sbjct: 611 SDSDSSDSDSSNSSDSDSSDSSDSSSSDSSDSDSDSKDSTSDSSDDNSKSGNGNSDSDSD 670
Query: 741 SNSNDQGSSDTSVTQDD 757
S+S+ +GS T DD
Sbjct: 671 SDSDSEGSDSNHSTSDD 687
Score = 119 bits (299), Expect = 2e-26
Identities = 85/448 (18%), Positives = 191/448 (41%), Gaps = 15/448 (3%)
Query: 93 KHDEQTKLDDVNGVE--DNSEHKEDSVEQESEESSQNAKTDLEGEQHTEKVDEENDNAEN 150
+ DE T D G + D E + + E + S N +G TE ++D+ E
Sbjct: 246 EEDEDTGSGDGVGADAGDGRESHDGTEGHEGQSSGGNNDNRGQGSVSTE----DDDSKEQ 301
Query: 151 KENESVEKENEEIKKEVEDTETGESIEEKSHLENEESKETGEISEEKS----HLENEESK 206
+ + + + E E G+ + +N E G IS+ ++ +N+ +
Sbjct: 302 EGSPNGRGGDNTSSSEETGIEEGDGTQTTQDNQNLSPTEGGIISQAEACPSGQSQNQGLE 361
Query: 207 ETGESSEEKSHLENEESKETGESSEEKSHLENEENKDEEKSKQENEEIKDGEKIQQENE- 265
G S+ KS + E K +G H + ++ K + ++ EK N
Sbjct: 362 TEGSSTGNKSSITKESGKLSGSKDSNGHHGMELDKRNSPKQGESDKPQGAAEKSDTHNNM 421
Query: 266 -ENKDEEKSQQENEENKD-EEKSQQENELKKNEGGEKETGEITEEKSKQENEETSETNSK 323
++ S + ++ D +++S Q ++ N E + +++ + + E
Sbjct: 422 GHSRIGSSSNSDGHDSYDFDDESMQGDD--PNSSDESNGSDGSDDANSESAIENGNHGDA 479
Query: 324 DKENEESNQNGSDAKEQVGENHEQDSKQGTEETNGTEGGEKEEHDKIKEDTSSDNQVQDG 383
++ES+ NGSD+ GE+ D T++++ + E DK + D S+ + D
Sbjct: 480 SYTSDESSDNGSDSDSHAGEDDSSDDTSDTDDSDSNGDDDSESKDKDESDNSNHDNDSDS 539
Query: 384 EKNNEAREENYSGDNASSAVVDNKSQESSNKTEEQFDKKEKNEFELESQKNSNETTESTD 443
E +++ + + ++S + + S E+S+ ++ + + NS++T++S+D
Sbjct: 540 ESKSDSSDSDSDSSDSSDSSDSSDSSETSDSSDSSDTSDSSDSSDSSDSSNSSDTSDSSD 599
Query: 444 STITQNSQGNESEKDQAQTENDTPKGSASESDEQKQEQEQNNTTKDDVQTTDTSSQNGND 503
S+ +S G+ S+ D + +++ S S + +++ D +T SS + +
Sbjct: 600 SSDGDSSDGDSSDSDSSDSDSSNSSDSDSSDSSDSSSSDSSDSDSDSKDSTSDSSDDNSK 659
Query: 504 TTEKQNETSEDANSKKEDSSALNTTPNN 531
+ +++ D++S E S + ++T ++
Sbjct: 660 SGNGNSDSDSDSDSDSEGSDSNHSTSDD 687
Score = 77.8 bits (190), Expect = 1e-13
Identities = 47/266 (17%), Positives = 115/266 (42%), Gaps = 23/266 (8%)
Query: 83 DEEEADELDNKHDEQTKLDDVNGVEDNSEHKEDSVEQE---------SEESSQNAKTDLE 133
D + D+ + D+ D+ NG + + + +S + S+ESS N +
Sbjct: 436 DSYDFDDESMQGDDPNSSDESNGSDGSDDANSESAIENGNHGDASYTSDESSDNGS---D 492
Query: 134 GEQHTEKVDEENDNAENKENESVEKENEEIKKEVEDTETGESIEEKSHLENEESKETGEI 193
+ H + D +D ++ +++S ++ E K + E + + S +++ S +
Sbjct: 493 SDSHAGEDDSSDDTSDTDDSDSNGDDDSESKDKDESDNSNHDNDSDSESKSDSSDSDSDS 552
Query: 194 SEEKSHLENEESKETGESSEEKSHLENEESKETGESSEEKSHLENEENKDEEKSKQENEE 253
S+ ++ +S ET +SS+ ++ +S ++ +SS ++ ++ D + S
Sbjct: 553 SDSSDSSDSSDSSETSDSSDSSDTSDSSDSSDSSDSSNSSDTSDSSDSSDGDSS------ 606
Query: 254 IKDGEKIQQENEENKDEEKSQQENEENKDEEKSQQENELKKNEGGEKETGEITEEKSKQE 313
DG+ + ++ D + S + ++ D S + + + T + +++ SK
Sbjct: 607 --DGD---SSDSDSSDSDSSNSSDSDSSDSSDSSSSDSSDSDSDSKDSTSDSSDDNSKSG 661
Query: 314 NEETSETNSKDKENEESNQNGSDAKE 339
N + + D ++E S+ N S + +
Sbjct: 662 NGNSDSDSDSDSDSEGSDSNHSTSDD 687
Score = 64.3 bits (155), Expect = 1e-09
Identities = 39/211 (18%), Positives = 97/211 (45%), Gaps = 6/211 (2%)
Query: 77 DARHKEDE--EEADELDNKHDEQTKLDDVNGVEDN-SEHKEDSVEQESEES-SQNAKTDL 132
DA + DE + + D+ E DD + +D+ S +DS ++ +ES + N D
Sbjct: 478 DASYTSDESSDNGSDSDSHAGEDDSSDDTSDTDDSDSNGDDDSESKDKDESDNSNHDNDS 537
Query: 133 EGEQHTEKVDEENDNAENKENESVEKENEEIKKEVEDTETGESIEEKSHLENEESKETGE 192
+ E ++ D ++D++++ ++ S ++ E + ++T +S + ++ S +T +
Sbjct: 538 DSESKSDSSDSDSDSSDSSDS-SDSSDSSETSDSSDSSDTSDSSDSSDSSDSSNSSDTSD 596
Query: 193 ISEEKSHLENE-ESKETGESSEEKSHLENEESKETGESSEEKSHLENEENKDEEKSKQEN 251
S+ ++ +S ++ S + S+ + +S ++ +SS S + ++KD ++
Sbjct: 597 SSDSSDGDSSDGDSSDSDSSDSDSSNSSDSDSSDSSDSSSSDSSDSDSDSKDSTSDSSDD 656
Query: 252 EEIKDGEKIQQENEENKDEEKSQQENEENKD 282
+++ + D E S + + D
Sbjct: 657 NSKSGNGNSDSDSDSDSDSEGSDSNHSTSDD 687
Score = 51.2 bits (121), Expect = 1e-05
Identities = 37/193 (19%), Positives = 84/193 (43%), Gaps = 16/193 (8%)
Query: 62 GRKDLKPRVEETSVIDARHKEDEEEADELDNKHDEQTKLDDVNGVEDNSEHKEDSVE-QE 120
G D +T D+ +D E D+ ++ + D D+S+ DS + +
Sbjct: 498 GEDDSSDDTSDTDDSDSNGDDDSESKDKDESDNSNHDNDSDSESKSDSSDSDSDSSDSSD 557
Query: 121 SEESSQNAKTDLEGEQHTEKVDEENDNAENKENESVEKENEEIKKEVEDTETGESIEEKS 180
S +SS +++T ++ D + + + ++S + N + D+ G+S
Sbjct: 558 SSDSSDSSET-------SDSSDSSDTSDSSDSSDSSDSSNSSDTSDSSDSSDGDS----- 605
Query: 181 HLENEESKETGEISEEKSHLENEESKETGESSEEKSHLENEESKE-TGESSEEKSHLENE 239
+ +S ++ + S+ + +S ++ +SS S + +SK+ T +SS++ S N
Sbjct: 606 --SDGDSSDSDSSDSDSSNSSDSDSSDSSDSSSSDSSDSDSDSKDSTSDSSDDNSKSGNG 663
Query: 240 ENKDEEKSKQENE 252
+ + S ++E
Sbjct: 664 NSDSDSDSDSDSE 676
Score = 43.5 bits (101), Expect = 0.002
Identities = 26/173 (15%), Positives = 71/173 (41%), Gaps = 1/173 (0%)
Query: 51 STKTGNEVVKLGRKDLKPRVEETSVIDARHKEDEEEADELDNKHDEQTKLDDVNGVEDNS 110
S G++ + KD + D+ K D ++D + + + D + D+S
Sbjct: 512 SDSNGDDDSESKDKDESDNSNHDNDSDSESKSDSSDSDSDSSDSSDSSDSSDSSETSDSS 571
Query: 111 EHKEDSVEQESEESSQNAKTDLEGEQHTEKVDEENDNAENKENESVEKENEEIKKEVEDT 170
+ + S +S +SS ++ + + ++ D ++ + ++ +++S + ++
Sbjct: 572 DSSDTSDSSDSSDSSDSSNSS-DTSDSSDSSDGDSSDGDSSDSDSSDSDSSNSSDSDSSD 630
Query: 171 ETGESIEEKSHLENEESKETGEISEEKSHLENEESKETGESSEEKSHLENEES 223
+ S + S +++ T + S++ S N S +S + ++ S
Sbjct: 631 SSDSSSSDSSDSDSDSKDSTSDSSDDNSKSGNGNSDSDSDSDSDSEGSDSNHS 683
>GARP_PLAFF (P13816) Glutamic acid-rich protein precursor
Length = 678
Score = 134 bits (337), Expect = 9e-31
Identities = 143/691 (20%), Positives = 281/691 (39%), Gaps = 104/691 (15%)
Query: 89 ELDNKHDEQTKLDDVNGVEDNSEHKEDSVEQESEESSQNAKTDLEGEQHTEKVDEENDNA 148
EL+ D+ +K + + +++ + K+D V S ++ +NA + E T+ + N N
Sbjct: 54 ELEKNKDDNSKSETL--LKEEKDEKDD-VPTTSNDNLKNAHNNNEISSSTDPTNIINVND 110
Query: 149 ENKENESVEKENEEIKKEVEDTETGESIEEKSHLENEESKETGEISEEKSHLENEESKET 208
++ EN SV+K+ ++ +EK H ++++ K+ E+K E ++ KE
Sbjct: 111 KDNEN-SVDKKKDK--------------KEKKHKKDKKEKK-----EKKDKKEKKDKKEK 150
Query: 209 GESSEEKSHLENEESKE---------TGESSEEKSHLENEENKDEEKSKQENEEIKDG-- 257
+ +EK H ++++ KE TG+ + + EEN DEE + N + G
Sbjct: 151 -KHKKEKKHKKDKKKKENSEVMSLYKTGQHKPKNATEHGEENLDEEMVSEINNNAQGGLL 209
Query: 258 ----------------EKIQQENEENKDEEK---SQQENEENKDEE--KSQQENELKKNE 296
+ + + + KD +K S+ + E+++ EE K+ + E K+ E
Sbjct: 210 LSSPYQYREQGGCGIISSVHETSNDTKDNDKENISEDKKEDHQQEEMLKTLDKKERKQKE 269
Query: 297 GGEKETGEITEEKSKQENEE--TSETNSKDKENEESNQNGSDAKEQVGENHEQDSKQGTE 354
KE +I ++K KQE +E E K +E +E Q + K+Q E+ K+ E
Sbjct: 270 KEMKEQEKIEKKKKKQEEKEKKKQEKERKKQEKKERKQKEKEMKKQKKIEKERKKKEEKE 329
Query: 355 ETNGTEGGEKEEHDKIKEDTSSDNQVQDGEKNNEAREENYSGDNASSAVVDNKSQESSNK 414
+ +K++HDK E+T E NNE S + ++K E +
Sbjct: 330 K-------KKKKHDKENEETMQQPDQTSEETNNEIMVPLPSPLTDVTTPEEHKEGEHKEE 382
Query: 415 TEEQFDKKEKNEFELESQKNSNETTESTDSTITQNSQGNESEKDQAQTENDTPKGSASES 474
++ + KE E E ++ ++ E ++S++ +++ + D K +
Sbjct: 383 EHKEGEHKEGEHKEEEHKEEEHKKEE------------HKSKEHKSKGKKDKGKKDKGKH 430
Query: 475 DEQKQEQEQNNTTKDDVQTTDTSSQNGNDTTEKQNETSEDANSKKEDSSALNTTPNNEDS 534
+ K+E+ + + K+ ++ D D E N ED + +E + + P ++
Sbjct: 431 KKAKKEKVKKHVVKNVIEDED------KDGVEIIN--LEDKEACEEQHITVESRPLSQPQ 482
Query: 535 KSGVAGDQADSTTTTSSSETQDGNTNHGEYKDTTNENPEKNSGQEGTQESGSSSNTFDNK 594
+ D+ + T S+ ++ N + E+ G G + K
Sbjct: 483 CKLI--DEPEQLTLMDKSKVEEKNLS----------IQEQLIGTIGRVNVVPRRDNHKKK 530
Query: 595 DAASNKVQLTTTSDTSSEQ-KKDESSSAESKSESSQNDNANSGQSNTTSDESANDNKDSS 653
A + +L E+ KK+ES + +S+ Q D + DE + ++
Sbjct: 531 MAKIEEAELQKQKHVDKEEDKKEESKEVQEESKEVQED-----EEEVEEDEEEEEEEEEE 585
Query: 654 QVTTSSENSAEGNSNTENNSDENQNDSKNNENTNDSGNTSNDANVNENQNENAAQTKTSE 713
+ E E E DE++ D + E D D + E+ +E + +
Sbjct: 586 EEEEEEEEEEEEEEEEEEEEDEDEEDEDDAEEDEDDAEEDED-DAEEDDDEEDDDEEDDD 644
Query: 714 NEGDAQNESVESKKENNESAHKDVDNNSNSN 744
+ D E E ++E E + K + N N
Sbjct: 645 EDEDEDEEDEEEEEEEEEESEKKIKRNLRKN 675
Score = 130 bits (327), Expect = 1e-29
Identities = 134/695 (19%), Positives = 279/695 (39%), Gaps = 117/695 (16%)
Query: 61 LGRKDLKPRVEETSVIDARHKEDEEEADELDNKHDEQTKLDDVNGVEDNSEHKEDSVEQE 120
L +L+ ++ S + KE+++E D++ ++ K + H + +
Sbjct: 50 LNETELEKNKDDNSKSETLLKEEKDEKDDVPTTSNDNLK----------NAHNNNEISSS 99
Query: 121 SEESSQNAKTDLEGEQHTEKVDEENDNAENKENESVEKENEEIKKEVEDTETGESIEEKS 180
++ ++ D + E +K ++ + K+ + EK+ ++ KKE +D + + +EK
Sbjct: 100 TDPTNIINVNDKDNENSVDKKKDKKEKKHKKDKK--EKKEKKDKKEKKDKKEKKHKKEKK 157
Query: 181 HLENEESKETGEI-----------------------SEEKSHLENE-----------ESK 206
H ++++ KE E+ E S + N + +
Sbjct: 158 HKKDKKKKENSEVMSLYKTGQHKPKNATEHGEENLDEEMVSEINNNAQGGLLLSSPYQYR 217
Query: 207 ETG-----ESSEEKSHLENEESKETGESSEEKSHLENEENK--DEEKSKQENEEIKDGEK 259
E G S E S+ + KE +++ H + E K D+++ KQ+ +E+K+ EK
Sbjct: 218 EQGGCGIISSVHETSNDTKDNDKENISEDKKEDHQQEEMLKTLDKKERKQKEKEMKEQEK 277
Query: 260 IQQENEENKDEEKSQQENEENKDE--EKSQQENELKKNEGGEKETGEITEEKSKQENEET 317
I+++ ++ +++EK +QE E K E E+ Q+E E+KK + EK E K K+E E+
Sbjct: 278 IEKKKKKQEEKEKKKQEKERKKQEKKERKQKEKEMKKQKKIEK------ERKKKEEKEKK 331
Query: 318 SETNSKDKENEESNQNGSDAKEQVGENHEQDSKQGTEETNGTEGGEKEEHDKIKEDTSSD 377
+ + DKENEE+ Q E+ + E ++ EH KE+ +
Sbjct: 332 KKKH--DKENEETMQQPDQTSEETNNEIMVPLPSPLTDVTTPEEHKEGEH---KEEEHKE 386
Query: 378 NQVQDGE-KNNEAREENYSGDNASSAVVDNKSQESSNKTEEQFDKKEKNEFELESQKNSN 436
+ ++GE K E +EE + + ++KS+E +K ++ KK+K K+
Sbjct: 387 GEHKEGEHKEEEHKEEEHKKE-------EHKSKEHKSKGKKDKGKKDKG-------KHKK 432
Query: 437 ETTESTDSTITQNSQGNESEKDQAQTENDTPKGSASESDEQKQEQEQNNTTKDDVQTTDT 496
E + +N +E +KD + N K + +EQ E ++ + D
Sbjct: 433 AKKEKVKKHVVKNVIEDE-DKDGVEIINLEDKEAC---EEQHITVESRPLSQPQCKLIDE 488
Query: 497 SSQNGNDTTEKQNETSEDANSKKEDS-----SALNTTPNNEDSKSGVAGDQADSTTTTSS 551
Q T E+ N ++ +N P ++ K +A + +
Sbjct: 489 PEQ----LTLMDKSKVEEKNLSIQEQLIGTIGRVNVVPRRDNHKKKMA--KIEEAELQKQ 542
Query: 552 SETQDGNTNHGEYKDTTNENPEKNSGQEGTQESGSSSNTFDNKDAASNKVQLTTTSDTSS 611
E K+ E+ E +E +E D ++ + + +
Sbjct: 543 KHVDKEEDKKEESKEVQEESKEVQEDEEEVEE--------DEEEEEEEEEEEEEEEEEEE 594
Query: 612 EQKKDESSSAESKSESSQNDNANSGQSNTTSDESANDNKDSSQVTTSSENSAEGNSNTEN 671
E++++E E + E + D++ D D+ + +E + + E
Sbjct: 595 EEEEEEEEEEEDEDEEDE-------------DDAEEDEDDAEEDEDDAEEDDDEEDDDEE 641
Query: 672 NSDENQNDSKNNENTNDSGNTSNDANVNENQNENA 706
+ DE++++ + +E + ++ + N +NA
Sbjct: 642 DDDEDEDEDEEDEEEEEEEEEESEKKIKRNLRKNA 676
Score = 126 bits (317), Expect = 2e-28
Identities = 119/654 (18%), Positives = 270/654 (41%), Gaps = 59/654 (9%)
Query: 144 ENDNAENKENESVEKE--NE-EIKKEVEDTETGESIEEKSHLENEESKETGEISEEKSHL 200
+N N NK +S+ NE E++K +D E++ ++ E ++ T + + +H
Sbjct: 33 KNQNILNKSFDSITGRLLNETELEKNKDDNSKSETLLKEEKDEKDDVPTTSNDNLKNAHN 92
Query: 201 ENEESKETGESSE-EKSHLENEESKETGESSEEKSHLENEENKDEEKSKQENEEIKDGEK 259
NE S T ++ + +NE S + + +EK H ++++ K E+K K+E ++ K+ +K
Sbjct: 93 NNEISSSTDPTNIINVNDKDNENSVDKKKDKKEKKHKKDKKEKKEKKDKKEKKDKKE-KK 151
Query: 260 IQQENEENKDEEKSQQENEENKDEEKSQQENELKKNEGGEKETGE--ITEEKSKQEN--- 314
++E + KD++K +EN E K+ Q E GE+ E ++E + +
Sbjct: 152 HKKEKKHKKDKKK--KENSEVMSLYKTGQHKPKNATEHGEENLDEEMVSEINNNAQGGLL 209
Query: 315 ----------------EETSETNSKDKENEESNQNGSDAKEQVGENHEQDSKQGTEETNG 358
ET++ K+N++ N E E+H+Q+ T +
Sbjct: 210 LSSPYQYREQGGCGIISSVHETSNDTKDNDKEN-----ISEDKKEDHQQEEMLKTLDKKE 264
Query: 359 TEGGEKE--EHDKI--KEDTSSDNQVQDGEKNNEAREENYSGDNASSAVVDNKSQESSNK 414
+ EKE E +KI K+ + + + EK + +E+ K ++ K
Sbjct: 265 RKQKEKEMKEQEKIEKKKKKQEEKEKKKQEKERKKQEKKERKQKEKEMKKQKKIEKERKK 324
Query: 415 TEEQFDKKEKNEFELE-SQKNSNETTESTDSTIT-------QNSQGNESEKDQAQTENDT 466
EE+ KK+K++ E E + + ++T+E T++ I + E K+ E +
Sbjct: 325 KEEKEKKKKKHDKENEETMQQPDQTSEETNNEIMVPLPSPLTDVTTPEEHKEGEHKEEEH 384
Query: 467 PKGSASESDEQKQEQEQNNTTKDDVQTTDTSSQNGNDTTEKQNETSEDANSKKEDSSALN 526
+G E + +++E ++ K++ ++ + S+ D +K + A +K +
Sbjct: 385 KEGEHKEGEHKEEEHKEEEHKKEEHKSKEHKSKGKKDKGKKDKGKHKKAKKEKVKKHVVK 444
Query: 527 TTPNNEDSKSGVAGDQADSTTTTSSSETQDGNTNHGEYKDTTNENPEKNSGQEGTQESGS 586
+ED D + + + H + P+ E Q +
Sbjct: 445 NVIEDEDK---------DGVEIINLEDKEACEEQHITVESRPLSQPQCKLIDEPEQLTLM 495
Query: 587 SSNTFDNKDAASNKVQLTTTSDTSSEQKKDESSSAESKSESSQNDNANSGQSNTTSDESA 646
+ + K+ + + + T + ++D +K E ++ E +
Sbjct: 496 DKSKVEEKNLSIQEQLIGTIGRVNVVPRRDNHKKKMAKIEEAELQKQKHVDKEEDKKEES 555
Query: 647 NDNKDSSQVTTSSENSAEGNSNTENNSDENQNDSKNNENTNDSGNTSNDANVNENQNENA 706
+ ++ S+ E E + E +E + + + E + + + +E ++A
Sbjct: 556 KEVQEESKEVQEDEEEVEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEDEDEEDEDDA 615
Query: 707 AQTKTSENEGDAQNESVESKKENNESAHKDVDNNSNSNDQGSSDTSVTQDDKES 760
E+E DA+ + +++++++E + D++ + ++ + ++++ES
Sbjct: 616 -----EEDEDDAEEDEDDAEEDDDEEDDDEEDDDEDEDEDEEDEEEEEEEEEES 664
Score = 125 bits (314), Expect = 4e-28
Identities = 103/531 (19%), Positives = 223/531 (41%), Gaps = 59/531 (11%)
Query: 40 HSREQKASYGASTKTGNEVVKLGRKDL-KPRVEETSVIDARHKEDEEEADELDN------ 92
H +E+K K +EV+ L + KP+ + DEE E++N
Sbjct: 152 HKKEKKHKKDKKKKENSEVMSLYKTGQHKPK---NATEHGEENLDEEMVSEINNNAQGGL 208
Query: 93 ------KHDEQTKLDDVNGVEDNSEHKEDSVEQESEESSQNAKTDLEGEQHTEKVDEEND 146
++ EQ ++ V + S D+ + + E S++ K D + E+ + +D++
Sbjct: 209 LLSSPYQYREQGGCGIISSVHETSN---DTKDNDKENISEDKKEDHQQEEMLKTLDKKER 265
Query: 147 NAENKENESVEKENEEIKKEVEDTETGESIEEKSHLENEESKETGEISEEKSHLENEESK 206
+ KE + EK ++ KK+ E + + E K + E ++ E+ ++K + + K
Sbjct: 266 KQKEKEMKEQEKIEKKKKKQEEKEKKKQEKERKKQEKKERKQKEKEMKKQKKIEKERKKK 325
Query: 207 ETGESSEEKSHLENEESKETGESSEEKSHLE--------------NEENKDEEKSKQENE 252
E E ++K ENEE+ + + + E+++ E EE+K+ E ++E++
Sbjct: 326 EEKEKKKKKHDKENEETMQQPDQTSEETNNEIMVPLPSPLTDVTTPEEHKEGEHKEEEHK 385
Query: 253 EIKDGEKIQQENEENKDEEKSQQENEENKDEEKSQQENELKKNEGGEKETGEITEEKSKQ 312
E E++E + +E+ +E E K+E KS++ K + G+K+ G+ + K ++
Sbjct: 386 E--------GEHKEGEHKEEEHKEEEHKKEEHKSKEHKSKGKKDKGKKDKGKHKKAKKEK 437
Query: 313 ENEETSETNSKDKENEESNQNGSDAKEQVGENHEQDSKQGTEETNGTEGGEKE-----EH 367
+ + +D++ + + KE E H + + E E +
Sbjct: 438 VKKHVVKNVIEDEDKDGVEIINLEDKEACEEQHITVESRPLSQPQCKLIDEPEQLTLMDK 497
Query: 368 DKIKEDTSSDNQV-------------QDGEKNNEAREENYSGDNASSAVVDNKSQESSNK 414
K++E S + +D K A+ E + +E S +
Sbjct: 498 SKVEEKNLSIQEQLIGTIGRVNVVPRRDNHKKKMAKIEEAELQKQKHVDKEEDKKEESKE 557
Query: 415 TEEQFDKKEKNEFELESQKNSNETTESTDSTITQNSQGNESEKDQAQTENDTPKGSASES 474
+E+ + +++E E+E + E E + + + E E+++ + + D +E
Sbjct: 558 VQEESKEVQEDEEEVEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEDEDEEDEDDAEE 617
Query: 475 DEQKQEQEQNNTTKDDVQTTDTSSQNGNDTTEKQNETSEDANSKKEDSSAL 525
DE E+++++ +DD + D + D E + + E+ ++E +
Sbjct: 618 DEDDAEEDEDDAEEDDDEEDDDEEDDDEDEDEDEEDEEEEEEEEEESEKKI 668
Score = 111 bits (278), Expect = 6e-24
Identities = 122/632 (19%), Positives = 246/632 (38%), Gaps = 67/632 (10%)
Query: 159 ENEEIKKEVEDTETGESIEEKSHLENEESKETGEISEEKSHLENEESKETGESSEEKSHL 218
+N+ I + D+ TG + E +N++ E ++ E ++ T + + +H
Sbjct: 33 KNQNILNKSFDSITGRLLNETELEKNKDDNSKSETLLKEEKDEKDDVPTTSNDNLKNAHN 92
Query: 219 ENEESKETGESSEEKSHLENEENKDEEKS--KQENEEIKDGEKIQQENEENKDEEKSQQE 276
NE S SS + +++ N +KD E S K+++++ K +K ++E +E KD+++ + +
Sbjct: 93 NNEIS-----SSTDPTNIINVNDKDNENSVDKKKDKKEKKHKKDKKEKKEKKDKKEKKDK 147
Query: 277 NEENKDEEKSQQENELKKNEGGEKETGEITEEKSKQENEETSETNSKDKENE-ESNQNGS 335
E+ +EK ++++ KK + + K K E E ++ +E +N G
Sbjct: 148 KEKKHKKEKKHKKDKKKKENSEVMSLYKTGQHKPKNATEHGEENLDEEMVSEINNNAQGG 207
Query: 336 DAKEQVGENHEQDS----KQGTEETNGTEGGEKEEHDKIKEDTSSDNQVQDGEKNNEARE 391
+ EQ E +N T+ +KE I ED D+Q ++ K + +E
Sbjct: 208 LLLSSPYQYREQGGCGIISSVHETSNDTKDNDKEN---ISEDKKEDHQQEEMLKTLDKKE 264
Query: 392 ENYSGDNASSAVVDNKSQESSNKTEEQFDKKEKNEFELESQKNSNETTESTDSTITQNSQ 451
K +E K +E+ +KK+K + E E +K E +
Sbjct: 265 R--------------KQKEKEMKEQEKIEKKKKKQEEKEKKKQEKERKK----------- 299
Query: 452 GNESEKDQAQTENDTPKGSASESDEQKQEQEQNNTTKDDVQTTDTSSQNGNDTTEKQNET 511
+ +K++ Q E + K E + +K+E+++ K D + +T Q + E NE
Sbjct: 300 --QEKKERKQKEKEMKKQKKIEKERKKKEEKEKKKKKHDKENEETMQQPDQTSEETNNEI 357
Query: 512 SEDANSKKEDSSALNTTPNNEDSKSGVAGDQADSTTTTSSSETQDGNTNHGEYKDTTNEN 571
S D TTP E+ K G ++ E ++ E+K +++
Sbjct: 358 MVPLPSPLTDV----TTP--EEHKEGEHKEEEHKEGEHKEGEHKEEEHKEEEHKKEEHKS 411
Query: 572 PEKNSGQEGTQESGSSSNTFDNKDAASNKVQLTTTSDTSSEQKKDESSSAESKSESSQND 631
E S +G ++ G +K A KV+ + ++ KD + + + +
Sbjct: 412 KEHKS--KGKKDKGKKDKG-KHKKAKKEKVKKHVVKNVIEDEDKDGVEIINLEDKEACEE 468
Query: 632 NANSGQSNTTSDESANDNKDSSQVTTSSENSAEGNSNTENNSDENQNDSKNNENTNDSGN 691
+ +S S + Q+T D+++ + KN
Sbjct: 469 QHITVESRPLSQPQCKLIDEPEQLTLM---------------DKSKVEEKNLSIQEQLIG 513
Query: 692 TSNDANVNENQNENAAQTKTSENEGDAQNESVESKKENNESAHKDVDNNSNSNDQGSSDT 751
T NV ++ + + E E + Q + K+E+ + K+V S + +
Sbjct: 514 TIGRVNVVPRRDNHKKKMAKIE-EAELQKQKHVDKEEDKKEESKEVQEESKEVQEDEEEV 572
Query: 752 SVTQDDKESRVDLGTLPESNGESHHNDVSSAE 783
++++E + E E + E
Sbjct: 573 EEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEE 604
Score = 110 bits (276), Expect = 1e-23
Identities = 96/420 (22%), Positives = 184/420 (42%), Gaps = 67/420 (15%)
Query: 60 KLGRKDLKPRVEETSVIDARHKEDEEEADELDNKHDEQTKLDDVNGVEDNSEHKEDSVEQ 119
K RK + ++E I+ + K+ EE+ E+ K + ++ E K+ E
Sbjct: 262 KKERKQKEKEMKEQEKIEKKKKKQEEK---------EKKKQEKERKKQEKKERKQKEKEM 312
Query: 120 ESEES-SQNAKTDLEGEQHTEKVDEENDNAENKENESVEKENEEIK----KEVEDTETGE 174
+ ++ + K E E+ +K D+EN+ + +++ E+ N EI + D T E
Sbjct: 313 KKQKKIEKERKKKEEKEKKKKKHDKENEETMQQPDQTSEETNNEIMVPLPSPLTDVTTPE 372
Query: 175 SIEEKSHLENEESK---ETGEISEEKSHLENEESKETGESSEEKSHLENEESKET----- 226
+E H E E + + GE EE+ H E E KE +S E KS + ++ K+
Sbjct: 373 EHKEGEHKEEEHKEGEHKEGEHKEEE-HKEEEHKKEEHKSKEHKSKGKKDKGKKDKGKHK 431
Query: 227 -GESSEEKSHLENEENKDEEKSKQENEEIKDGEKIQQEN--------------------- 264
+ + K H+ +DE+K E ++D E ++++
Sbjct: 432 KAKKEKVKKHVVKNVIEDEDKDGVEIINLEDKEACEEQHITVESRPLSQPQCKLIDEPEQ 491
Query: 265 ----EENKDEEKSQQENEE------------NKDEEKSQ----QENELKKNEGGEKETGE 304
+++K EEK+ E+ +D K + +E EL+K + +KE E
Sbjct: 492 LTLMDKSKVEEKNLSIQEQLIGTIGRVNVVPRRDNHKKKMAKIEEAELQKQKHVDKE--E 549
Query: 305 ITEEKSKQENEETSETNSKDKENEESNQNGSDAKEQVGENHEQDSKQGTEETNGTEGGEK 364
+E+SK+ EE+ E ++E EE + + +E+ E E++ ++ EE E ++
Sbjct: 550 DKKEESKEVQEESKEVQEDEEEVEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEDEDE 609
Query: 365 EEHDKIKEDTSSDNQVQDGEKNNEAREENYSGDNASSAVVDNKSQESSNKTEEQFDKKEK 424
E+ D +ED + +D + ++ E++ D+ D + +E + EE+ +KK K
Sbjct: 610 EDEDDAEEDEDDAEEDEDDAEEDDDEEDDDEEDDDEDEDEDEEDEEEEEEEEEESEKKIK 669
Score = 103 bits (257), Expect = 2e-21
Identities = 77/379 (20%), Positives = 183/379 (47%), Gaps = 36/379 (9%)
Query: 42 REQKASYGASTKTGNEVVKLGRKDLKPRV--EETSVIDARHKEDEEEADELDNKHDEQTK 99
+E+K K + +K +K K R EE +H ++ EE + ++ E+T
Sbjct: 295 KERKKQEKKERKQKEKEMKKQKKIEKERKKKEEKEKKKKKHDKENEETMQQPDQTSEETN 354
Query: 100 ----------LDDVNGVEDNSE------------HKEDSVEQESEESSQNAKTDLEGEQH 137
L DV E++ E HKE ++E + ++ K + + ++H
Sbjct: 355 NEIMVPLPSPLTDVTTPEEHKEGEHKEEEHKEGEHKEGEHKEEEHKEEEHKKEEHKSKEH 414
Query: 138 TEKVDEENDNAENKENESVEKEN--EEIKKEVEDTETGESIEEKSHLENEESKETGEISE 195
K ++ + +++ +KE + + K V + E + +E +LE++E+ E I+
Sbjct: 415 KSKGKKDKGKKDKGKHKKAKKEKVKKHVVKNVIEDEDKDGVEI-INLEDKEACEEQHITV 473
Query: 196 EKSHLENEESKETGESSEEKSHLENEESKETGESSEEK--------SHLENEENKDEEKS 247
E L + K E E+ + ++ + +E S +E+ + + +N ++ +
Sbjct: 474 ESRPLSQPQCKLIDEP-EQLTLMDKSKVEEKNLSIQEQLIGTIGRVNVVPRRDNHKKKMA 532
Query: 248 KQENEEIKDGEKIQQENEENKDEEKSQQENEENKDEEKSQQENELKKNEGGEKETGEITE 307
K E E++ + + +E ++ ++ ++ Q+E++E +++E+ +E+E ++ E E+E E E
Sbjct: 533 KIEEAELQKQKHVDKEEDKKEESKEVQEESKEVQEDEEEVEEDEEEEEEEEEEEEEEEEE 592
Query: 308 EKSKQENEETSETNSKDKENEESNQNGSDAKEQVGENHEQDSKQGTEETNGTEGGEKEEH 367
E+ ++E EE E + +++ +++ ++ DA+E + E D ++ +E + E +++E
Sbjct: 593 EEEEEEEEEEEEEDEDEEDEDDAEEDEDDAEEDEDDAEEDDDEEDDDEEDDDEDEDEDEE 652
Query: 368 DKIKEDTSSDNQVQDGEKN 386
D+ +E+ + + ++N
Sbjct: 653 DEEEEEEEEEESEKKIKRN 671
Score = 94.0 bits (232), Expect = 1e-18
Identities = 78/294 (26%), Positives = 138/294 (46%), Gaps = 44/294 (14%)
Query: 77 DARHKEDEEEADELDNK-HDEQTKLDDVNGVEDNSEHKEDSVEQESEESSQNAKTDLEGE 135
+ HKE+E + +E +K H + K D G +D +HK+ E+ + +N D E +
Sbjct: 396 EEEHKEEEHKKEEHKSKEHKSKGKKD--KGKKDKGKHKKAKKEKVKKHVVKNVIED-EDK 452
Query: 136 QHTEKVDEENDNAENKENESVEK------------ENEEI----KKEVEDTETGESIEEK 179
E ++ E+ A +++ +VE E E++ K +VE E SI+E+
Sbjct: 453 DGVEIINLEDKEACEEQHITVESRPLSQPQCKLIDEPEQLTLMDKSKVE--EKNLSIQEQ 510
Query: 180 ---------------SHLENEESKETGEISEEKSHLENEESKETGESSEEKSHLENEESK 224
+H + E E+ ++K H++ EE K+ E+S EESK
Sbjct: 511 LIGTIGRVNVVPRRDNHKKKMAKIEEAELQKQK-HVDKEEDKK------EESKEVQEESK 563
Query: 225 ETGESSEEKSHLENEENKDEEKSKQENEEIKDGEKIQQENEENKDEEKSQQENEENKDEE 284
E E EE E EE ++EE+ ++E EE ++ E+ ++E EE++DEE E+ D E
Sbjct: 564 EVQEDEEEVEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEDEDEEDEDDAEEDEDDAE 623
Query: 285 KSQQENELKKNEGGEKETGEITEEKSKQENEETSETNSKDKENEESNQNGSDAK 338
+ + + E +E + E + +E +E+EE E ++ E + +AK
Sbjct: 624 EDEDDAEEDDDEEDDDEEDDDEDEDEDEEDEEEEEEEEEESEKKIKRNLRKNAK 677
Score = 57.8 bits (138), Expect = 1e-07
Identities = 34/133 (25%), Positives = 70/133 (52%), Gaps = 1/133 (0%)
Query: 37 QIGHSREQKASYGASTKTGNEVVKLGRKDLKPRVEETSVIDARHKEDEEEADELDNKHDE 96
+I + QK + + E K +++ K E+ ++ +E+EEE +E + + +E
Sbjct: 533 KIEEAELQKQKHVDKEEDKKEESKEVQEESKEVQEDEEEVEEDEEEEEEEEEEEEEEEEE 592
Query: 97 QTKLDDVNGVEDNSEHKEDSVE-QESEESSQNAKTDLEGEQHTEKVDEENDNAENKENES 155
+ + ++ E+ E +ED + +E E+ ++ + D E + E DEE+D+ + E+E
Sbjct: 593 EEEEEEEEEEEEEDEDEEDEDDAEEDEDDAEEDEDDAEEDDDEEDDDEEDDDEDEDEDEE 652
Query: 156 VEKENEEIKKEVE 168
E+E EE ++E E
Sbjct: 653 DEEEEEEEEEESE 665
>ATRX_PANTR (Q7YQM4) Transcriptional regulator ATRX (X-linked helicase
II) (X-linked nuclear protein) (XNP)
Length = 2492
Score = 132 bits (331), Expect = 5e-30
Identities = 146/723 (20%), Positives = 307/723 (42%), Gaps = 88/723 (12%)
Query: 67 KPRVEETSVIDARHKEDEEEADELDNKHDEQTKLDDVNGVE-------------DNSEHK 113
K + ++S+I + ++ + E+ D++ +++ K G D+SE +
Sbjct: 794 KGKSAKSSIISKKKRQTQSESSNYDSELEKEIKSMSKIGAARTTKKRIPNTKDFDSSEDE 853
Query: 114 EDSVEQESEESSQNAKTDLEGEQHTEKVDEENDNAENKENESVEKEN------EEIKKEV 167
+ S + + +N KT EG + +E +N + E +V+K+ + + K+
Sbjct: 854 KHSKKGMDNQGHKNLKTSQEGSSDDAERKQERENFSSAEG-TVDKDTTIMELRDRLPKKQ 912
Query: 168 EDTETGESIEEKSHLENE----ESKETGEISEEKSHLENEESKET--GESSEEKSHLENE 221
+ + + + +++ S E E ++ E E+ HL+ + K+ G S + L+ +
Sbjct: 913 QASASTDGVDKFSGKEESFTSLEVRKVAETKEKSKHLKTKTCKKVQDGLSDTAEKFLKKD 972
Query: 222 ESKETGESSEEKSHLENEENKDEEKSKQENEEIKDGEKIQQENEENKDEEKSQQENEENK 281
+S ET E +++S K E+ K+ ++ K K++Q+ E + D + E EE
Sbjct: 973 QSDETSEDDKKQS------KKGTEEKKKPSDFKKKVIKMEQQYESSSDGTEKLPEREEIC 1026
Query: 282 DEEKSQQENELKKNEGGEKETGEITEEKSKQENE-------ETSETNSKDKENEESNQNG 334
K ++ + +G EK++ +I ++ SK+++E T + +S D ++ ++NG
Sbjct: 1027 HFPKGIKQIKNGTTDG-EKKSKKIRDKTSKKKDELSDYAEKSTGKGDSCDSSEDKKSKNG 1085
Query: 335 SDAKEQV--------GENHEQDSKQGTEETNGTEGGEKEEHDKIKEDTSSDNQVQDGEKN 386
+ +E+ + S TE+ + E G ++K + + ++N
Sbjct: 1086 AYGREKKRCKLLGKSSRKRQDCSSSDTEKYSMKEDGCNSSDKRLKRIELRERRNLSSKRN 1145
Query: 387 NEAREENYSGDNASSAVVDNKSQESSNKTEEQFDKKEKNEFELESQKNSNET-TESTDST 445
+ E SG ++S A +S E + K +++ K+K E ++NS T T+ +
Sbjct: 1146 TK---EIQSGSSSSDA---EESSEDNKKKQQRTSSKKKAVIVKEKKRNSLRTSTKRKQAD 1199
Query: 446 ITQNSQGNESEKDQAQTENDTPKGSASESDEQKQEQEQNNTTKDDVQTTDTSSQNGNDTT 505
IT +S + + DQ N +GS SDEQK + N T +G++
Sbjct: 1200 ITSSSSSDIEDDDQ----NSIGEGS---SDEQKIKPVTENLVLSS--HTGFCQSSGDEAL 1250
Query: 506 EKQNE-TSEDANSKKEDSSALNTTPNNEDSKSGVAGDQADSTTTTSSSETQDGNTNHGEY 564
K T +D + + + + E+ K+ ++ D+ S S E ++G
Sbjct: 1251 SKSVPVTVDDDDDDNDPENRIAKKMLLEEIKANLSSDEDGS----SDDEPEEG------- 1299
Query: 565 KDTTNENPEKNSGQEGTQESGSSSNTFDNKDAASNKV-------QLTTTSDTSSEQKKDE 617
K T + E+N G E + +S + D++++ + +LT + S E+KK +
Sbjct: 1300 KKRTGKQNEENPGDEEAKNQVNSESDSDSEESKKPRYRHRLLRHKLTVSDGESGEEKKTK 1359
Query: 618 SS-----SAESKSESSQNDNANSGQSNTTSDESANDNKDSSQVTTSSENSAEGNSNTENN 672
++ + S D+ +S + E ++++D + T S AE N +
Sbjct: 1360 PKEHKEVKGRNRRKVSSEDSEDSDFQESGVSEEVSESEDEQRPRTRSAKKAELEENQRSY 1419
Query: 673 SDENQNDSKNNENTNDSGNTSNDANVNENQNENAAQTKTSENEGDAQNESVESKKENNES 732
+ + + + S N SN E + E + + E E + +N+ +S + +
Sbjct: 1420 KQKKKRRRIKVQEDSSSENKSNSEEEEEEKEEEEEEEEEEEEEEEDENDDSKSPGKGRKK 1479
Query: 733 AHK 735
K
Sbjct: 1480 IRK 1482
Score = 109 bits (272), Expect = 3e-23
Identities = 141/744 (18%), Positives = 289/744 (37%), Gaps = 68/744 (9%)
Query: 56 NEVVKLGRKDLKPRVEETSVIDARHKEDEEEADELDNKHDEQTKLDDVNGVEDNSEHKED 115
NE VK +K P ++ D R+ D + NK + + + V+ D+ E
Sbjct: 682 NETVKEKQKLSVPVRKK----DKRNSSDSAIDNPKPNKLPKSKQSETVDQNSDSDEMLAI 737
Query: 116 SVEQESEESSQNAKTDLEGEQHTEKVDEENDNAENKENESVEKENEEIKKEVEDTETGES 175
E S ++ TD+ K + K+++ K DT+ G+S
Sbjct: 738 LKEVSRMSHSSSSDTDINEIHTNHKTLYDLKTQAGKDDKGKRKRKSSTSGSDFDTKKGKS 797
Query: 176 IEEKSHLENEESKET-GEISEEKSHLENE--ESKETGESSEEKSHLENEESKETGESSEE 232
KS + +++ ++T E S S LE E + G + K + N +K+ S +E
Sbjct: 798 A--KSSIISKKKRQTQSESSNYDSELEKEIKSMSKIGAARTTKKRIPN--TKDFDSSEDE 853
Query: 233 KSHLENEENKDEEKSKQENEEIKDGEKIQQENEENKDEEKSQQENEENKDEEKSQQENEL 292
K + +N+ + K E D + +QE E S E +KD + + L
Sbjct: 854 KHSKKGMDNQGHKNLKTSQEGSSDDAERKQERENF-----SSAEGTVDKDTTIMELRDRL 908
Query: 293 KKNEGGEKETGEITEEKSKQEN------EETSETNSKDKENEESN----QNG-------- 334
K + T + + K+E+ + +ET K K + Q+G
Sbjct: 909 PKKQQASASTDGVDKFSGKEESFTSLEVRKVAETKEKSKHLKTKTCKKVQDGLSDTAEKF 968
Query: 335 --SDAKEQVGENHEQDSKQGTEETNGTEGGEKEEHDKIKEDTSSDNQVQDGEKNNEAREE 392
D ++ E+ ++ SK+GTEE +K+ D K+ + Q + E E
Sbjct: 969 LKKDQSDETSEDDKKQSKKGTEE-------KKKPSDFKKKVIKMEQQYESSSDGTEKLPE 1021
Query: 393 NYSGDNASSAV--VDNKSQESSNKTEEQFDKKEKNEFEL----ESQKNSNETTESTDSTI 446
+ + + N + + K+++ DK K + EL E ++ +S++
Sbjct: 1022 REEICHFPKGIKQIKNGTTDGEKKSKKIRDKTSKKKDELSDYAEKSTGKGDSCDSSEDKK 1081
Query: 447 TQN-SQGNESEKDQAQTENDTPKGSASESDEQKQEQEQNNTTKDDVQTTDTSSQNGNDTT 505
++N + G E ++ + ++ + S SD +K +++ D + + + +
Sbjct: 1082 SKNGAYGREKKRCKLLGKSSRKRQDCSSSDTEKYSMKEDGCNSSDKRLKRIELRERRNLS 1141
Query: 506 EKQN-------ETSEDANSKKEDSSALNTTPNNEDSKSGVAGDQADSTTTTSSSETQDGN 558
K+N +S DA ED+ +++ K+ + ++ ++ TS+ Q
Sbjct: 1142 SKRNTKEIQSGSSSSDAEESSEDNKKKQQRTSSK-KKAVIVKEKKRNSLRTSTKRKQADI 1200
Query: 559 TNHGEYKDTTNENPEKNSGQEGTQESGSSSNTFDNKDAASNKVQLTTTSDTSSEQKKDES 618
T+ + E+ ++NS EG+ + +N +S+ T +S ++ +S
Sbjct: 1201 TSSSS---SDIEDDDQNSIGEGSSDEQKIKPVTENLVLSSH----TGFCQSSGDEALSKS 1253
Query: 619 SSAESKSESSQNDNANSGQSNTTSDESANDNKDSSQVTTSSENSAEGNSNTENNSDENQN 678
+ ND N +E N S + +S + EG T ++EN
Sbjct: 1254 VPVTVDDDDDDNDPENRIAKKMLLEE-IKANLSSDEDGSSDDEPEEGKKRTGKQNEENPG 1312
Query: 679 DSKNNENTNDSGNTSNDANVNENQNENAAQTKTSENEGDAQNESVESKKENNE--SAHKD 736
D + N ++ ++ + + K + ++G++ E KE+ E ++
Sbjct: 1313 DEEAKNQVNSESDSDSEESKKPRYRHRLLRHKLTVSDGESGEEKKTKPKEHKEVKGRNRR 1372
Query: 737 VDNNSNSNDQGSSDTSVTQDDKES 760
++ +S D ++ V+++ ES
Sbjct: 1373 KVSSEDSEDSDFQESGVSEEVSES 1396
Score = 99.8 bits (247), Expect = 3e-20
Identities = 125/647 (19%), Positives = 269/647 (41%), Gaps = 105/647 (16%)
Query: 73 TSVIDARHKEDEEEADELDNKHDEQTKLDDVNGVEDNSEH--KEDSVEQESEESSQNAKT 130
TS+ + E +E++ L K ++ + +G+ D +E K+D ++ SE+ + +K
Sbjct: 932 TSLEVRKVAETKEKSKHLKTKTCKKVQ----DGLSDTAEKFLKKDQSDETSEDDKKQSKK 987
Query: 131 DLEGEQHTE-------KVDEENDNAENKENESVEKEN-----EEIKKEVEDTETGESIEE 178
E ++ K++++ +++ + + E+E + IK+ T GE +
Sbjct: 988 GTEEKKKPSDFKKKVIKMEQQYESSSDGTEKLPEREEICHFPKGIKQIKNGTTDGEKKSK 1047
Query: 179 KSHLENEESKETGEISE--EKSHLENE--ESKETGESSEEKSHLENEESKETGESSEEKS 234
K + ++ SK+ E+S+ EKS + + +S E +S E + K G+SS ++
Sbjct: 1048 K--IRDKTSKKKDELSDYAEKSTGKGDSCDSSEDKKSKNGAYGREKKRCKLLGKSSRKRQ 1105
Query: 235 HLENEENKD----EEKSKQENEEIKDGEKIQQENEENKDEEKSQQENEENKDEEKSQQEN 290
+ + + E+ ++ +K E ++ N +K K Q + D E+S ++N
Sbjct: 1106 DCSSSDTEKYSMKEDGCNSSDKRLKRIELRERRNLSSKRNTKEIQSGSSSSDAEESSEDN 1165
Query: 291 ELKKNEGGEKETGEITEEK--------SKQENEETSETNSKDKENEESNQNGSDAKEQ-- 340
+ K+ K+ I +EK +K++ + + ++S D E+++ N G + ++
Sbjct: 1166 KKKQQRTSSKKKAVIVKEKKRNSLRTSTKRKQADITSSSSSDIEDDDQNSIGEGSSDEQK 1225
Query: 341 ---VGENHEQDSKQGTEETNGTEGGEKEEHDKIKEDTSSDNQVQDGEKNNEAREE---NY 394
V EN S G +++G E K + +D DN ++ EE N
Sbjct: 1226 IKPVTENLVLSSHTGFCQSSGDEALSKSVPVTV-DDDDDDNDPENRIAKKMLLEEIKANL 1284
Query: 395 SGDNASSAVVDNKSQESSNKTEEQFDKKEKNEFELESQKNSNETTESTDSTITQNSQGNE 454
S D S+ D++ +E +T +Q + + G+E
Sbjct: 1285 SSDEDGSS--DDEPEEGKKRTGKQ----------------------------NEENPGDE 1314
Query: 455 SEKDQAQTENDTPKGSASESDEQKQEQEQNNTTKDDVQTTDTSSQNGNDTTEKQNETSED 514
K+Q +E+D S+S+E K+ + ++ + + +D S T K+++ +
Sbjct: 1315 EAKNQVNSESD------SDSEESKKPRYRHRLLRHKLTVSDGESGEEKKTKPKEHKEVKG 1368
Query: 515 ANSKKEDSSALNTTPNNEDSKSGVAGDQADS----TTTTSSSETQDGNTNHGEYKDTTNE 570
N +K S + +++ +SGV+ + ++S T S++ + N YK
Sbjct: 1369 RNRRKVSS---EDSEDSDFQESGVSEEVSESEDEQRPRTRSAKKAELEENQRSYKQ---- 1421
Query: 571 NPEKNSGQEGTQESGSSSNTFDNKDAASNKVQLTTTSDTSSEQKKDESSSAESKSESSQN 630
+K + QE SS N ++++ K E++++E E + E +
Sbjct: 1422 --KKKRRRIKVQEDSSSENKSNSEEEEEEK-----------EEEEEEEEEEEEEEEDEND 1468
Query: 631 DNANSGQSNTTSDESANDNKDSSQVTTSSENSAEGNSNTENNSDENQ 677
D+ + G+ + D+K ++ + + E E +
Sbjct: 1469 DSKSPGKGRKKIRKILKDDKLRTETQNALKEEEERRKRIAERERERE 1515
Score = 99.4 bits (246), Expect = 3e-20
Identities = 141/704 (20%), Positives = 275/704 (39%), Gaps = 81/704 (11%)
Query: 102 DVNGVEDNSEHKEDSVEQESEESSQNAKTDLEGEQHTEKVDEENDNAENKENESVEKENE 161
+ N V NS+ + + +E ++ S + + +D N K K++E
Sbjct: 669 ETNPVTSNSDEECNETVKEKQKLSVPVRKKDKRNSSDSAIDNPKPNKLPKS-----KQSE 723
Query: 162 EIKKEVEDTETGESIEEKSHLENEESKET--GEISEEKSHL--------ENEESKETGES 211
+ + + E ++E S + + S +T EI L ++++ K +S
Sbjct: 724 TVDQNSDSDEMLAILKEVSRMSHSSSSDTDINEIHTNHKTLYDLKTQAGKDDKGKRKRKS 783
Query: 212 SEEKSHLENEESKETGESSEEKSHLENEENKDEEKSKQENEEIKDGEKI------QQENE 265
S S + ++ K S K + + S+ E +EIK KI ++
Sbjct: 784 STSGSDFDTKKGKSAKSSIISKKKRQTQSESSNYDSELE-KEIKSMSKIGAARTTKKRIP 842
Query: 266 ENKDEEKSQQENEENKDEEKSQQENELKKNEGGEKETGEITEEKSKQENEETSE-TNSKD 324
KD + S+ E K + +N EG + E K ++EN ++E T KD
Sbjct: 843 NTKDFDSSEDEKHSKKGMDNQGHKNLKTSQEGSSDDA----ERKQERENFSSAEGTVDKD 898
Query: 325 ------KENEESNQNGSDAKEQVGE-NHEQDSKQGTEETNGTEGGEKEEHDKIKEDTSSD 377
++ Q S + + V + + +++S E E EK +H K T +
Sbjct: 899 TTIMELRDRLPKKQQASASTDGVDKFSGKEESFTSLEVRKVAETKEKSKHLK----TKTC 954
Query: 378 NQVQDGEKNNEAREENYSGDNASSAVVDNKSQESSNKTEEQFDKKEKNEFELESQKNSNE 437
+VQDG ++ E+ D + D+K Q S TEE KK+ ++F+ + K +
Sbjct: 955 KKVQDGL--SDTAEKFLKKDQSDETSEDDKKQ-SKKGTEE---KKKPSDFKKKVIKMEQQ 1008
Query: 438 TTESTDST--ITQNSQGNESEKDQAQTENDTPKGSASESDEQKQEQEQNNTTKDDVQTTD 495
S+D T + + + K Q +N T G + K+ +++ + KD++
Sbjct: 1009 YESSSDGTEKLPEREEICHFPKGIKQIKNGTTDGEK----KSKKIRDKTSKKKDEL---- 1060
Query: 496 TSSQNGNDTTEKQNETSEDANSKKEDSSALNTTPNNEDSKSGVAGDQADSTTTTSSSETQ 555
+D EK + +S ED + N E + + G + SSS+T+
Sbjct: 1061 ------SDYAEKSTGKGDSCDSS-EDKKSKNGAYGREKKRCKLLGKSSRKRQDCSSSDTE 1113
Query: 556 ------------DGNTNHGEYKDTTNENPEKNSGQEGTQESGSSSNTFDNKDAASNKVQL 603
D E ++ N + ++N+ + Q SSS+ ++ + K Q
Sbjct: 1114 KYSMKEDGCNSSDKRLKRIELRERRNLSSKRNTKE--IQSGSSSSDAEESSEDNKKKQQR 1171
Query: 604 TTTSDTSSEQKKDESSSAESKSESSQNDNANSGQSNTTSDES---ANDNKDSSQVTTSSE 660
T++ + K+ + +S + ++ Q D +S S+ D+ + D ++ +E
Sbjct: 1172 TSSKKKAVIVKEKKRNSLRTSTKRKQADITSSSSSDIEDDDQNSIGEGSSDEQKIKPVTE 1231
Query: 661 NSAEGNSNTENNSDENQNDSKNNENTNDSGNTSNDAN---VNENQNENAAQTKTSENEGD 717
N + S ++ SK+ T D + ND + E +S+ +G
Sbjct: 1232 NLVLSSHTGFCQSSGDEALSKSVPVTVDDDDDDNDPENRIAKKMLLEEIKANLSSDEDGS 1291
Query: 718 AQNESVESKKENNESAHKDVDNNSNSNDQGSSDTSVTQDDKESR 761
+ +E E KK + ++ + N S S +++ K+ R
Sbjct: 1292 SDDEPEEGKKRTGKQNEENPGDEEAKNQVNSESDSDSEESKKPR 1335
Score = 87.0 bits (214), Expect = 2e-16
Identities = 67/274 (24%), Positives = 128/274 (46%), Gaps = 42/274 (15%)
Query: 82 EDEEEADELDNKHDEQTKLDDVNGVEDNSEHKEDSVEQESEESSQNAKTDLEGEQHTEKV 141
+D+++ ++ +N+ ++ L+++ N ED + E EG++ T K
Sbjct: 1259 DDDDDDNDPENRIAKKMLLEEIKA---NLSSDEDGSSDDEPE---------EGKKRTGKQ 1306
Query: 142 DEEN---DNAENKENESVEKENEEIKKE------------VEDTETGESIEEKSHLENEE 186
+EEN + A+N+ N + ++EE KK V D E+GE + K +E
Sbjct: 1307 NEENPGDEEAKNQVNSESDSDSEESKKPRYRHRLLRHKLTVSDGESGEEKKTKP----KE 1362
Query: 187 SKETGEISEEKSHLENEESKETGESSEEKSHLENEESKETGESSEEKSHLENEENKDEEK 246
KE + K E+ E + ES + E+E+ + S +K+ LE + ++K
Sbjct: 1363 HKEVKGRNRRKVSSEDSEDSDFQESGVSEEVSESEDEQRPRTRSAKKAELEENQRSYKQK 1422
Query: 247 SKQENEEIK-DGEKIQQENEENKDEEKSQQENEENKDEEKSQQENELKKNEG-GEKETGE 304
K+ +++ D + N E ++EEK ++E EE ++EE+ + EN+ K+ G G K+ +
Sbjct: 1423 KKRRRIKVQEDSSSENKSNSEEEEEEKEEEEEEEEEEEEEEEDENDDSKSPGKGRKKIRK 1482
Query: 305 I---------TEEKSKQENEETSETNSKDKENEE 329
I T+ K+E E +++E E+
Sbjct: 1483 ILKDDKLRTETQNALKEEEERRKRIAEREREREK 1516
Score = 80.5 bits (197), Expect = 2e-14
Identities = 140/717 (19%), Positives = 265/717 (36%), Gaps = 57/717 (7%)
Query: 96 EQTKLDDVNGVEDNSEHKEDSVEQESEESSQNAKTDLEGEQHTEKVDEENDNAENKENES 155
EQ + ++ +SE E S S + ++ GE+ +K+D+ + +
Sbjct: 288 EQLLQQNKKKIKVDSEKSNKVYEHTSRFSPKKTSSNCNGEE--KKLDDSCSGSVTYSYSA 345
Query: 156 VEKENEEIKKEVEDTETGESIEEKSHLENEESKETGEISEEKSHLENEESKETGESSEEK 215
+ E IKK + ET ++ +++ + EIS + L ++ ++ + +K
Sbjct: 346 LIVPKEMIKKAKKLIETTANMNSSYVKFLKQATDNSEISSA-TKLRQLKAFKSVLADIKK 404
Query: 216 SHLENEESKETGESSEEKSHLENEENKDEEKSKQENEEIKDGEKIQQENEENKDEEKSQ- 274
+HL EE + + E+N E K E K + + E KD KS+
Sbjct: 405 AHLALEE--DLNSEFRAMDAVNKEKNTKEHKVIDAKFETKARKGEKPCALEKKDISKSEA 462
Query: 275 -----QENEENKDEEKSQQENELKKNEGGEKETGEITEEKSKQENEETSETNSKDKENEE 329
Q + E+ D+ +E K+ GGE + + EE + E TSE D +
Sbjct: 463 KLSRKQVDSEHMDQNVPTEEQRANKSTGGEHKKSDRKEEP-QYEPANTSEDLDMDIVSVP 521
Query: 330 SN------QNGSDAKE-QVGENHEQDSKQGTEETNGTEGGEKEEHDKIKEDTSSDNQVQD 382
S+ +N A E Q +H+ D GTE+ + E +K + SS +
Sbjct: 522 SSVPEDIFENLETAMEVQSSVDHQGDGSSGTEQ--------EVESSSVKLNISSKDNRGG 573
Query: 383 GEKNNEAREENYSGDNASSAVVDNKSQESSNKTEEQFDKKEKNEFELES--QKNSNETTE 440
+ A+ + + N + ++ E DK L +K
Sbjct: 574 IKSKTTAKVTKELYVKLTPVSLSNSPIKGADCQEVPQDKDGYKSCGLNPKLEKCGLGQEN 633
Query: 441 STDSTITQNSQG---NESEKDQAQTENDTPKGSASESDE--QKQEQEQNNTTKD----DV 491
S + + +N ES+ ++ TP +E++ ++E N T K+ V
Sbjct: 634 SDNEHLVENEVSLLLEESDLRRSPRVKTTPLRRPTETNPVTSNSDEECNETVKEKQKLSV 693
Query: 492 QTTDTSSQNGNDTTEKQNETSEDANSKKEDSSALNTTPNNEDSKSGVAGDQADSTTTTSS 551
+N +D+ + ++ SK+ + T N DS +A + S + SS
Sbjct: 694 PVRKKDKRNSSDSAIDNPKPNKLPKSKQSE-----TVDQNSDSDEMLAILKEVSRMSHSS 748
Query: 552 SETQDGN---TNHGEYKDTTNENPEKNSGQEGTQESGSSSNTFDNKDAASNKVQLTTTSD 608
S D N TNH D + + + G+ ++S +S + FD K S K + +
Sbjct: 749 SSDTDINEIHTNHKTLYDLKTQAGKDDKGKR-KRKSSTSGSDFDTKKGKSAKSSIISKK- 806
Query: 609 TSSEQKKDESSSAESKSESSQNDNANSGQSNTTSDESAN-----DNKDSSQVTTSSENSA 663
Q + ESS+ +S+ E + G + TT N ++D +N
Sbjct: 807 --KRQTQSESSNYDSELEKEIKSMSKIGAARTTKKRIPNTKDFDSSEDEKHSKKGMDNQG 864
Query: 664 EGNSNT--ENNSDENQNDSKNNENTNDSGNTSNDANVNENQNENAAQTKTSENEGDAQNE 721
N T E +SD+ + + ++ G D + E ++ + + S +
Sbjct: 865 HKNLKTSQEGSSDDAERKQERENFSSAEGTVDKDTTIMELRDRLPKKQQASASTDGVDKF 924
Query: 722 SVESKKENNESAHKDVDNNSNSNDQGSSDTSVTQDDKESRVDLGTLPESNGESHHND 778
S + + + K + S + QD + + + E+ +D
Sbjct: 925 SGKEESFTSLEVRKVAETKEKSKHLKTKTCKKVQDGLSDTAEKFLKKDQSDETSEDD 981
Score = 75.9 bits (185), Expect = 4e-13
Identities = 83/357 (23%), Positives = 152/357 (42%), Gaps = 59/357 (16%)
Query: 79 RHKEDEEEADELDNKHDEQTKLDDVNGVEDNSEHKEDSVEQESEESSQNAKTDLEGEQHT 138
R + D + D + D+Q + G + E K V + SS G++
Sbjct: 1195 RKQADITSSSSSDIEDDDQNSI----GEGSSDEQKIKPVTENLVLSSHTGFCQSSGDEAL 1250
Query: 139 EK-----VDEENDNAENKENESVEKENEEIKKEVEDTETGESIEEKSHLENEESKETGEI 193
K VD+++D+ + + + + EEIK + E G S +E E K TG+
Sbjct: 1251 SKSVPVTVDDDDDDNDPENRIAKKMLLEEIKANLSSDEDGSSDDEPE----EGKKRTGKQ 1306
Query: 194 SEEK---SHLENEESKETGESSEEKSH-------LENEESKETGESSEEKSHL--ENEEN 241
+EE +N+ + E+ SEE L ++ + GES EEK E++E
Sbjct: 1307 NEENPGDEEAKNQVNSESDSDSEESKKPRYRHRLLRHKLTVSDGESGEEKKTKPKEHKEV 1366
Query: 242 KDEEKSKQENEEIKDGE----KIQQENEENKDEEKSQ---------QENEENKDEEKSQ- 287
K + K +E+ +D + + +E E++DE++ + +EN+ + ++K +
Sbjct: 1367 KGRNRRKVSSEDSEDSDFQESGVSEEVSESEDEQRPRTRSAKKAELEENQRSYKQKKKRR 1426
Query: 288 ----QENELKKNEGGEKETGEITEEKSKQENEETSETNSKDKENEESNQNGSDAKEQVGE 343
QE+ +N+ +E E EE+ ++E EE E ++ EN++S G K+
Sbjct: 1427 RIKVQEDSSSENKSNSEEEEEEKEEEEEEEEEEEEE---EEDENDDSKSPGKGRKKI--R 1481
Query: 344 NHEQDSKQGTEETNGTEGGEKEEHDKIKEDTSSDNQVQDGEKNNEAREENYSGDNAS 400
+D K TE N +KE+ ++ + E+ E E ++AS
Sbjct: 1482 KILKDDKLRTETQNA-----------LKEEEERRKRIAEREREREKLREVIEIEDAS 1527
Score = 70.5 bits (171), Expect = 2e-11
Identities = 102/514 (19%), Positives = 216/514 (41%), Gaps = 84/514 (16%)
Query: 41 SREQKASYGASTKTGNEVVKLGRKDLKPRVEETSVIDARH-KEDEEEADELDNKHDEQTK 99
S ++K+ GA + LG+ K + +S + KED + + K E +
Sbjct: 1077 SEDKKSKNGAYGREKKRCKLLGKSSRKRQDCSSSDTEKYSMKEDGCNSSDKRLKRIELRE 1136
Query: 100 LDDVNGVEDNSEHKEDSVEQESEESSQNAKTDLEGEQHTEKVDEENDNAENKENESVEKE 159
+++ + E + S ++EESS++ K + +K + N S +++
Sbjct: 1137 RRNLSSKRNTKEIQSGSSSSDAEESSEDNKKKQQRTSSKKKAVIVKEKKRNSLRTSTKRK 1196
Query: 160 NEEI----KKEVEDTET-----GESIEEKSHLENEE---SKETGEISEEKSHLENEESKE 207
+I ++ED + G S E+K E S TG ++
Sbjct: 1197 QADITSSSSSDIEDDDQNSIGEGSSDEQKIKPVTENLVLSSHTGFCQSSGDEALSKSVPV 1256
Query: 208 TGESSEEKSHLENEESKETGESSEEKSHLENEENKDEEKSKQENEEIKDGEKIQQENEEN 267
T + ++ + EN +K+ E K++L ++E+ + +E ++ + ++NEEN
Sbjct: 1257 TVDDDDDDNDPENRIAKKM-LLEEIKANLSSDEDGSSDDEPEEGKK-----RTGKQNEEN 1310
Query: 268 KDEE--KSQQENEENKDEEKSQQ--------ENELKKNEGGEKETGEITEEKSKQENEET 317
+E K+Q +E + D E+S++ ++L ++G E+GE + K K+ E
Sbjct: 1311 PGDEEAKNQVNSESDSDSEESKKPRYRHRLLRHKLTVSDG---ESGEEKKTKPKEHKEVK 1367
Query: 318 SETNSK--DKENEESNQNGSDAKEQVGENHEQD------SKQGTEETNGTEGGEKEEHDK 369
K +++E+S+ S E+V E+ ++ +K+ E N +K++ +
Sbjct: 1368 GRNRRKVSSEDSEDSDFQESGVSEEVSESEDEQRPRTRSAKKAELEENQRSYKQKKKRRR 1427
Query: 370 IK--EDTSSDNQVQDGEKNNEAREENYSGDNASSAVVDNKSQESSNKTEEQFDKKEKNEF 427
IK ED+SS+N+ E+ E EE EE+ +++E
Sbjct: 1428 IKVQEDSSSENKSNSEEEEEEKEEE-----------------------EEEEEEEE---- 1460
Query: 428 ELESQKNSNETTESTDSTITQNSQGNESEKDQAQTENDTPKGSASESDEQK----QEQEQ 483
E +++ N+ ++S + + + +K + +T+N + E +E++ + + +
Sbjct: 1461 --EEEEDENDDSKSPGKGRKKIRKILKDDKLRTETQN-----ALKEEEERRKRIAERERE 1513
Query: 484 NNTTKDDVQTTDTSSQNGNDTT----EKQNETSE 513
++ ++ D S TT ++ ET E
Sbjct: 1514 REKLREVIEIEDASPTKCPITTKLVLDEDEETKE 1547
Score = 55.5 bits (132), Expect = 5e-07
Identities = 103/605 (17%), Positives = 223/605 (36%), Gaps = 95/605 (15%)
Query: 258 EKIQQENEENKDEEKSQQENEENKDEEKSQ-QENELKKNEGGEKE------TGEITEEKS 310
E ++Q ++NK + K E E S+ + N GE++ +G +T S
Sbjct: 285 ENLEQLLQQNKKKIKVDSEKSNKVYEHTSRFSPKKTSSNCNGEEKKLDDSCSGSVTYSYS 344
Query: 311 KQENEETSETNSKDKENEESNQNGSDAK--EQVGENHEQDSKQGTEETNGTEG---GEKE 365
+ +K +N N S K +Q +N E S + + K+
Sbjct: 345 ALIVPKEMIKKAKKLIETTANMNSSYVKFLKQATDNSEISSATKLRQLKAFKSVLADIKK 404
Query: 366 EHDKIKEDTSSDNQVQDGEKNNEAREENYSGDNASSAVVDNKSQESSNKTEEQ--FDKKE 423
H ++ED +S+ + D + +E+ V+D K + + K E+ +KK+
Sbjct: 405 AHLALEEDLNSEFRAMDAVNKEKNTKEH--------KVIDAKFETKARKGEKPCALEKKD 456
Query: 424 --KNEFELESQKNSNETTES---TDSTITQNSQGNESEKDQAQTENDTPKGSASESDEQK 478
K+E +L ++ +E + T+ S G E +K + E + SE +
Sbjct: 457 ISKSEAKLSRKQVDSEHMDQNVPTEEQRANKSTGGEHKKSDRKEEPQYEPANTSEDLDMD 516
Query: 479 QEQEQNNTTKDDVQTTDTSSQNGNDTTEKQNETSEDANSKKEDSSALNTTPNNEDSKSGV 538
++ +D + +T+ + + + + +S ++ +SS++ +++D++ G+
Sbjct: 517 IVSVPSSVPEDIFENLETAMEVQSSVDHQGDGSS--GTEQEVESSSVKLNISSKDNRGGI 574
Query: 539 AGDQADSTTTTSSSETQDGNTNHGEYKDTT-NENPEKNSGQEGT------QESGSSSNTF 591
T + + ++ K E P+ G + ++ G
Sbjct: 575 KSKTTAKVTKELYVKLTPVSLSNSPIKGADCQEVPQDKDGYKSCGLNPKLEKCGLGQENS 634
Query: 592 DNKDAASNKVQLT-------------------------TTSDTSSE-------------- 612
DN+ N+V L TS++ E
Sbjct: 635 DNEHLVENEVSLLLEESDLRRSPRVKTTPLRRPTETNPVTSNSDEECNETVKEKQKLSVP 694
Query: 613 -QKKDESSSAESKSESSQ-NDNANSGQSNTTSDESANDN-----KDSSQVTTSSENSAEG 665
+KKD+ +S++S ++ + N S QS T S +D K+ S+++ SS + +
Sbjct: 695 VRKKDKRNSSDSAIDNPKPNKLPKSKQSETVDQNSDSDEMLAILKEVSRMSHSSSSDTDI 754
Query: 666 NSNTENN-------SDENQNDSKNNENTNDSGNTSNDANVNENQNENAAQTKTSENEGDA 718
N N+ + ++D + + + + D ++ + K + + ++
Sbjct: 755 NEIHTNHKTLYDLKTQAGKDDKGKRKRKSSTSGSDFDTKKGKSAKSSIISKKKRQTQSES 814
Query: 719 QNESVESKKENNESAHKDVDNNSNSNDQGSSDTSVTQDDKESRVDLGTLPESNGESHHND 778
N E +KE + + + D ++D+K S+ + + + H N
Sbjct: 815 SNYDSELEKEIKSMSKIGAARTTKKRIPNTKDFDSSEDEKHSKKGM------DNQGHKNL 868
Query: 779 VSSAE 783
+S E
Sbjct: 869 KTSQE 873
Score = 36.6 bits (83), Expect = 0.26
Identities = 39/165 (23%), Positives = 63/165 (37%), Gaps = 21/165 (12%)
Query: 148 AENKENESVEKENEEIKKEVEDTETGESIEEKSHLEN--------------EESKETGEI 193
+E+K N V+K ++ + E++E S + +N E SKE G
Sbjct: 7 SESKLNTLVQKLHDFLAHSSEESEETSSPPRLAMNQNTDKISGSGSNSDMMENSKEEGTS 66
Query: 194 SEEKSHLENEESKETGESSEEKSHLENEESKETGESSEEKSHLENEENKDEEKSKQENEE 253
S EKS + S K ++E E+ E + EN EN +S +
Sbjct: 67 SSEKSKSSGSSRSKRKPSIVTKYVESDDEKPLDDETVNEDASNENSENDITMQSLPKGTV 126
Query: 254 IKDGEKIQQENEENKDEEKSQQENEENKDEEKSQQENELKKNEGG 298
I E + +E+K + E + K + EN K+ E G
Sbjct: 127 IVQPEPV-------LNEDKDDFKGPEFRSRSKMKTENLKKRGEDG 164
Score = 34.3 bits (77), Expect = 1.3
Identities = 31/134 (23%), Positives = 51/134 (37%), Gaps = 21/134 (15%)
Query: 539 AGDQADSTTTTSSSETQDGNTNHGEYKDTTNENPEKNSGQEGTQESGSSSNTFDNKDAAS 598
A ++S T + D + E + T+ P Q + SGS SN+
Sbjct: 3 AEPMSESKLNTLVQKLHDFLAHSSEESEETSSPPRLAMNQNTDKISGSGSNS-------- 54
Query: 599 NKVQLTTTSDTSSEQKKDESSSAESKSESSQNDNANSGQSNTTSDESANDNKDSSQVTTS 658
E K+E +S+ KS+SS + + S T ++D K T +
Sbjct: 55 ----------DMMENSKEEGTSSSEKSKSSGSSRSKRKPSIVTKYVESDDEKPLDDETVN 104
Query: 659 SENSAEGNSNTENN 672
+ S N N+EN+
Sbjct: 105 EDAS---NENSEND 115
Score = 32.0 bits (71), Expect = 6.5
Identities = 19/91 (20%), Positives = 43/91 (46%), Gaps = 3/91 (3%)
Query: 658 SSENSAEGNSNTENNSDENQNDSKNNENTNDSGNTSNDANVNENQNENAAQTKTSENEGD 717
SSE S E +S ++N + + + +D S + + ++ ++ + S+ +
Sbjct: 25 SSEESEETSSPPRLAMNQNTDKISGSGSNSDMMENSKEEGTSSSEKSKSSGSSRSKRKPS 84
Query: 718 AQNESVESKKE---NNESAHKDVDNNSNSND 745
+ VES E ++E+ ++D N ++ ND
Sbjct: 85 IVTKYVESDDEKPLDDETVNEDASNENSEND 115
>DMP1_MOUSE (O55188) Dentin matrix acidic phosphoprotein 1 precursor
(Dentin matrix protein-1) (DMP-1) (AG1)
Length = 503
Score = 129 bits (325), Expect = 2e-29
Identities = 112/483 (23%), Positives = 218/483 (44%), Gaps = 39/483 (8%)
Query: 241 NKDEEKSKQENEEIKDGEKIQQENEENKDEEKSQQENEENKDEEKSQQENE-LKKNEGGE 299
N + E S++ +++ G N E+ +E ++ E + N D S + E L + G
Sbjct: 24 NTESESSEERTDDLA-GSPPPPTNSESSEESQASPEAQANSDHTHSSESGEELGYDRGQY 82
Query: 300 KETGEITEEKSKQENEETSETNSKDKE-NEESNQNGSDAKEQVGENHEQDSKQGTEETNG 358
+ G +++ +++ E +S D +E N G + + G + + + T
Sbjct: 83 RPAGGLSKSTGTGADKDDDEDDSGDDTFGDEDNGLGPEEGQWGGPSKLDSDEDSADTTQS 142
Query: 359 TEGGEKEEHDKIKEDTSSDNQVQDGEKNNEAREENYSGDNASSAVVDNKSQESSNKTEEQ 418
+E +E+ +DT SD++ QD E + +R + +GD+A + +++ Q +E Q
Sbjct: 143 SEDSTSQENSA--QDTPSDSKDQDSEDDAHSRPD--AGDSAQHS--ESEEQRVGGGSEGQ 196
Query: 419 FDKKEKNEFELES-QKNSNETTESTDSTITQNSQGNESEKDQAQTE----NDTPKGSASE 473
+ +EF+ E Q + E+T S +S G SE+ + E D+ + E
Sbjct: 197 SSHGDGSEFDDEGMQSDDPESTRSDRGHARMSSAGIRSEESKGDREPTSTQDSDDSQSVE 256
Query: 474 SDEQKQEQEQNNTTKD------DVQTTDTSSQNGNDTTEKQNETSEDANSKKEDSSALNT 527
+K + + +D D + +T S + DT K+ SE E S
Sbjct: 257 FSSRKSFRRSRVSEEDYRGELTDSNSRETQSDSTEDTASKEESRSESQEDTAESQSQ-ED 315
Query: 528 TPNNEDSKSGVAGDQADSTTTTSSSETQDGNTNHGEYKDTTNENPEKNSGQEGTQESGSS 587
+P +D S + ++A + SSSE+Q+G T+ ++ +NP+ N+ Q G QE S
Sbjct: 316 SPEGQDPSSE-SSEEAGEPSQESSSESQEGVTS-----ESRGDNPD-NTSQTGDQEDSES 368
Query: 588 SNTFDNKDAASNKVQLTTTSDTSSEQKKDESSSAESKSESSQNDNANSGQSNTTSDESAN 647
S + L T S + S+ ++++ S ++S S ++ S Q +S +
Sbjct: 369 ----------SEEDSLNTFSSSESQSTEEQADSESNESLSLSEESQESAQDGDSSSQEGL 418
Query: 648 DNKDSSQVTTSSENSAEGNSNTENNSDENQNDSKNNENTNDSGNTSNDANVNENQNENAA 707
++ +S + S E+ +E +S +E +SD +Q+ S++ E +N +G+ S+ +N A
Sbjct: 419 QSQSASTESRSQESQSEQDSRSEEDSD-SQDSSRSKEESNSTGSASSSEEDIRPKNMEAD 477
Query: 708 QTK 710
K
Sbjct: 478 SRK 480
Score = 118 bits (296), Expect = 5e-26
Identities = 103/475 (21%), Positives = 213/475 (44%), Gaps = 37/475 (7%)
Query: 294 KNEGGEKETGEITEEKSKQENEETSETNSKDKENEESNQN--GSDAKEQVGENHEQDSKQ 351
++E E+ T ++ N E+SE + E + ++ + S++ E++G + Q
Sbjct: 26 ESESSEERTDDLAGSPPPPTNSESSEESQASPEAQANSDHTHSSESGEELGYDRGQYRPA 85
Query: 352 GTEETNGTEGGEKEEHDKIKEDTSSDNQVQDGEKNNEAREENYSG----DNASSAVVDNK 407
G + G +K++ ED S D+ D + E + G D+ + +
Sbjct: 86 GGLSKSTGTGADKDDD----EDDSGDDTFGDEDNGLGPEEGQWGGPSKLDSDEDSADTTQ 141
Query: 408 SQESSNKTEEQFDKKEKNEFELESQKNSNETTESTDSTITQNSQGNESEKDQAQTENDTP 467
S E S E + + +S+ +++ ++ DS Q+S+ +E ++ +E +
Sbjct: 142 SSEDSTSQENSAQDTPSDSKDQDSEDDAHSRPDAGDSA--QHSE-SEEQRVGGGSEGQSS 198
Query: 468 KGSASESDEQKQEQEQNNTTKDDVQTTDTSSQNGNDTTEKQNETSEDANSKKEDSSALNT 527
G SE D++ + + +T+ D SS G + E + + + +DS ++
Sbjct: 199 HGDGSEFDDEGMQSDDPESTRSDRGHARMSSA-GIRSEESKGDREPTSTQDSDDSQSVEF 257
Query: 528 TPNNEDSKSGVAG-DQADSTTTTSSSETQDGNTNHGEYKDTTNENPEKNSGQEGTQESGS 586
+ +S V+ D T ++S ETQ +T +DT ++ ++ QE T ES S
Sbjct: 258 SSRKSFRRSRVSEEDYRGELTDSNSRETQSDST-----EDTASKEESRSESQEDTAESQS 312
Query: 587 SSNTFDNKDAASNKVQLTTTSDTSSEQKKDESSSAESKSESSQNDNANSGQSNTTSDESA 646
++ + +D +S SSE+ + S ES SES + + S N +
Sbjct: 313 QEDSPEGQDPSSE----------SSEEAGEPSQ--ESSSESQEGVTSESRGDNPDNTSQT 360
Query: 647 NDNKDSSQVTTSSENSAEGNSNTENNSDENQNDSKNNENTNDSGNTSNDANVNENQNENA 706
D +DS +S E+S S++E+ S E Q DS++NE+ + S + A ++ ++
Sbjct: 361 GDQEDSE---SSEEDSLNTFSSSESQSTEEQADSESNESLSLSEESQESAQDGDSSSQEG 417
Query: 707 AQTKTSENEGDAQNESVESKKENNESAHKDVDNNSNSNDQGSSDTSVTQDDKESR 761
Q++++ E +Q +S++++ D ++S S ++ +S S + +++ R
Sbjct: 418 LQSQSASTESRSQES--QSEQDSRSEEDSDSQDSSRSKEESNSTGSASSSEEDIR 470
Score = 107 bits (268), Expect = 9e-23
Identities = 93/464 (20%), Positives = 199/464 (42%), Gaps = 72/464 (15%)
Query: 91 DNKHDEQTKLDDVNGVEDNSEHKEDSVEQESEESSQNAKTDLEGEQHTEKVDEENDNAEN 150
D DE DD G EDN EE + L+ ++ + + ++++ +
Sbjct: 97 DKDDDEDDSGDDTFGDEDNG--------LGPEEGQWGGPSKLDSDEDSADTTQSSEDSTS 148
Query: 151 KENESVEKENEEIKKEVEDTETGESIEEKSHLENEESKETGEISEEKSHLENEESKETGE 210
+EN + + ++ ++ ED ++ + + H E+EE + G
Sbjct: 149 QENSAQDTPSDSKDQDSED----------------DAHSRPDAGDSAQHSESEEQRVGGG 192
Query: 211 SSEEKSHLENEESKETGESSEEKSHLENEENKDEEKSKQENEEIK-DGEKIQQENEENKD 269
S + SH + E + G S+ D E ++ + + I+ E +
Sbjct: 193 SEGQSSHGDGSEFDDEGMQSD-----------DPESTRSDRGHARMSSAGIRSEESKGDR 241
Query: 270 EEKSQQENEENKDEEKSQQENELKKNEGGEKETGEITEEKSKQ-ENEETSETNSKDKENE 328
E S Q++++++ E S +++ + E GE+T+ S++ +++ T +T SK++
Sbjct: 242 EPTSTQDSDDSQSVEFSSRKSFRRSRVSEEDYRGELTDSNSRETQSDSTEDTASKEESRS 301
Query: 329 ESNQNGSDAKEQVGENHEQDSKQGTEETNGTEGGEKEEHDKIKEDTSSDNQVQDGEKNNE 388
ES ++ ++++ Q +DS +G +D SS++ + GE + E
Sbjct: 302 ESQEDTAESQSQ------EDSPEG-------------------QDPSSESSEEAGEPSQE 336
Query: 389 AREENYSGDNASSAVVDNKSQESSNKTEEQFDKKEKNEFELESQKNSNETTESTDS---- 444
+ E+ G + S DN S +E + E++ S S T E DS
Sbjct: 337 SSSESQEGVTSESR-GDNPDNTSQTGDQEDSESSEEDSLNTFSSSESQSTEEQADSESNE 395
Query: 445 --TITQNSQGNESEKDQAQTENDTPKGSASESDEQKQEQEQNNTTKDDVQTTDTS-SQNG 501
++++ SQ + + D + E + +++ES Q+ + EQ++ +++D + D+S S+
Sbjct: 396 SLSLSEESQESAQDGDSSSQEGLQSQSASTESRSQESQSEQDSRSEEDSDSQDSSRSKEE 455
Query: 502 NDTTEKQNETSEDANSKKEDSSALNTTPNNEDSKSGVAGDQADS 545
+++T + + ED K ++ + + +K GDQ D+
Sbjct: 456 SNSTGSASSSEEDIRPKNMEADSRKLIVDAYHNKP--IGDQDDN 497
Score = 107 bits (266), Expect = 2e-22
Identities = 107/515 (20%), Positives = 213/515 (40%), Gaps = 50/515 (9%)
Query: 150 NKENESVEKENEEIKKEVEDTETGESIEEKSHLE----NEESKETGEISEEKSHLENEE- 204
N E+ES E+ +++ ES EE N + + E EE + +
Sbjct: 24 NTESESSEERTDDLAGSPPPPTNSESSEESQASPEAQANSDHTHSSESGEELGYDRGQYR 83
Query: 205 -----SKETGESSEEKSHLENEESKETGESSEEKSHLENEENKDEEKSKQENEEIKDGEK 259
SK TG +++ ++E+ +E + L EE + SK +++E D
Sbjct: 84 PAGGLSKSTGTGADKD---DDEDDSGDDTFGDEDNGLGPEEGQWGGPSKLDSDE--DSAD 138
Query: 260 IQQENEENKDEEKSQQENEENKDEEKSQQENELKKNEGGEKETGEITEEKSKQENEETSE 319
Q +E++ +E S Q+ + ++ S+ + + + G + E E++ +E S
Sbjct: 139 TTQSSEDSTSQENSAQDTPSDSKDQDSEDDAHSRPDAGDSAQHSESEEQRVGGGSEGQSS 198
Query: 320 TNSKDKENEESNQNGSDAKEQVGENHEQDSKQG--TEETNGTEGGEKEEHDKIKEDTSSD 377
+ ++E Q+ + H + S G +EE+ G + + S D
Sbjct: 199 HGDGSEFDDEGMQSDDPESTRSDRGHARMSSAGIRSEESKG-------DREPTSTQDSDD 251
Query: 378 NQVQDGEKNNEAREENYSGDNASSAVVDNKSQES-SNKTEEQFDKKEKNEFELESQKNSN 436
+Q + R S ++ + D+ S+E+ S+ TE D K E ESQ+++
Sbjct: 252 SQSVEFSSRKSFRRSRVSEEDYRGELTDSNSRETQSDSTE---DTASKEESRSESQEDTA 308
Query: 437 ETTESTDSTITQNSQGNESEKDQAQTENDTPKGSASESDEQKQEQEQNNTTKDDVQTTDT 496
E+ DS Q+ SE+ + S E E ++ T++ D
Sbjct: 309 ESQSQEDSPEGQDPSSESSEE------------AGEPSQESSSESQEGVTSESRGDNPDN 356
Query: 497 SSQNGNDTTEKQNETSEDANSKKEDSSALNTTPNNEDSKSGVAGDQADSTTTTSSSETQD 556
+SQ G+ ++ +E+SE+ + SS +T DS+S +++ S + S QD
Sbjct: 357 TSQTGD---QEDSESSEEDSLNTFSSSESQSTEEQADSES----NESLSLSEESQESAQD 409
Query: 557 GNTNHGEYKDTTNENPEKNSGQEGTQESGSSSNTFDNKDAASNKVQLTTTSDTSSEQKKD 616
G+++ E + + + E S + +++ S D++D++ +K + +T SS ++
Sbjct: 410 GDSSSQEGLQSQSASTESRSQESQSEQDSRSEEDSDSQDSSRSKEESNSTGSASSSEEDI 469
Query: 617 ESSSAESKSESSQNDNANSGQSNTTSDESANDNKD 651
+ E+ S D + + D+ ND +D
Sbjct: 470 RPKNMEADSRKLIVD---AYHNKPIGDQDDNDCQD 501
Score = 102 bits (253), Expect = 5e-21
Identities = 97/511 (18%), Positives = 201/511 (38%), Gaps = 36/511 (7%)
Query: 78 ARHKEDEEEADELDNKHDEQTKLDDVNGVEDNSEHKEDSVEQESEESSQNAKTDLEGEQH 137
AR+ E E+ E + DD+ G + E S E ++ +Q +
Sbjct: 20 ARYHNTESESSE--------ERTDDLAGSPPPPTNSESSEESQASPEAQANSDHTHSSES 71
Query: 138 TEKVDEENDNAENKENESVEKENEEIKKEVEDTETGESIEEKSHLENEESKETGEISEEK 197
E++ + S K + ED ++ ++ + E + G S+
Sbjct: 72 GEELGYDRGQYRPAGGLSKSTGTGADKDDDEDDSGDDTFGDEDNGLGPEEGQWGGPSKLD 131
Query: 198 SHLENEESKETGESSEEKSHLENEESKETGESSEEKSHLENEENKDEEKSKQENEEIKDG 257
S +E+S +T +SSE+ + EN +S ++ S + D S Q +E
Sbjct: 132 S---DEDSADTTQSSEDSTSQENSAQDTPSDSKDQDSEDDAHSRPDAGDSAQHSESE--- 185
Query: 258 EKIQQENEENKDEEKSQQENEENKDEEKSQQENELKKNEGGEKETGE--ITEEKSKQENE 315
+Q + + S + E DE + E +++ G I E+SK + E
Sbjct: 186 ---EQRVGGGSEGQSSHGDGSEFDDEGMQSDDPESTRSDRGHARMSSAGIRSEESKGDRE 242
Query: 316 ETSETNSKDKENEESNQNGSDAKEQV------GENHEQDSKQGTEETNGTEGGEKEEHDK 369
TS +S D ++ E + S + +V GE + +S++ ++ ++E +
Sbjct: 243 PTSTQDSDDSQSVEFSSRKSFRRSRVSEEDYRGELTDSNSRETQSDSTEDTASKEESRSE 302
Query: 370 IKEDTSSDNQVQDGEKNNEAREENYSGDNASSAVVDNKSQESSNKTEEQFDKKEKNEFEL 429
+EDT+ +D + + E SS SQESS++++E + + +
Sbjct: 303 SQEDTAESQSQEDSPEGQDPSSE-------SSEEAGEPSQESSSESQEGVTSESRGD--- 352
Query: 430 ESQKNSNETTESTDSTITQNSQGNESEKDQAQTENDTPKGSASESDEQKQEQEQNNTTKD 489
+ N+++T + DS ++ N ++Q+ + ++ES +E +++ D
Sbjct: 353 -NPDNTSQTGDQEDSESSEEDSLNTFSSSESQSTEEQADSESNESLSLSEESQESAQDGD 411
Query: 490 DVQTTDTSSQNGNDTTEKQNETSEDANSKKEDSSALNTTPNNEDSKSGVAGDQADSTTTT 549
SQ+ + + Q SE + +EDS + +++ + E+S S + ++
Sbjct: 412 SSSQEGLQSQSASTESRSQESQSEQDSRSEEDSDSQDSSRSKEESNSTGSASSSEEDIRP 471
Query: 550 SSSETQDGNTNHGEYKDTTNENPEKNSGQEG 580
+ E Y + + + N Q+G
Sbjct: 472 KNMEADSRKLIVDAYHNKPIGDQDDNDCQDG 502
Score = 82.4 bits (202), Expect = 4e-15
Identities = 85/359 (23%), Positives = 157/359 (43%), Gaps = 41/359 (11%)
Query: 40 HSREQKASYGASTKTGNEVVKLGRKDLKPRVEETSVIDARHKEDEEEADELDNKH----- 94
HSR +++ + V G + + + D + D+ E+ D H
Sbjct: 170 HSRPDAGDSAQHSESEEQRVGGGSEGQSSHGDGSEFDDEGMQSDDPESTRSDRGHARMSS 229
Query: 95 ----DEQTKLD-DVNGVEDNSEHKEDSVEQESEES---SQNAKTDLEGEQHTEKVDEEND 146
E++K D + +D+ + + SVE S +S S+ ++ D GE T+ E
Sbjct: 230 AGIRSEESKGDREPTSTQDSDDSQ--SVEFSSRKSFRRSRVSEEDYRGEL-TDSNSRETQ 286
Query: 147 NAENKENESVEKENEEIKKEVEDTETGESIEEKSHLENEESKETGEISEEKSHLENEESK 206
+ ++ S E+ E +++ ++++ E E +E S+E GE S+E S ES+
Sbjct: 287 SDSTEDTASKEESRSESQEDTAESQSQEDSPEGQDPSSESSEEAGEPSQESS----SESQ 342
Query: 207 ETGESSEEKSHLENEESKETGESSEEKSHLENEENKDEEKSKQENEEIKDGEKIQQENEE 266
E G +SE + + + +TG+ + +S E+ N Q EE Q ++E
Sbjct: 343 E-GVTSESRGD-NPDNTSQTGDQEDSESSEEDSLNTFSSSESQSTEE-------QADSES 393
Query: 267 NKDEEKSQQENEENKDEEKSQQENELKKNEGGEKETGEI-TEEKSKQENEETSETNSKDK 325
N+ S++ E +D + S QE ++ E + E +E+ S+ E + S+ +S+ K
Sbjct: 394 NESLSLSEESQESAQDGDSSSQEGLQSQSASTESRSQESQSEQDSRSEEDSDSQDSSRSK 453
Query: 326 ENEESNQNGSDAKEQV-GENHEQDSKQGTEETNGTEGGEKEEHDKIKEDTSSDNQVQDG 383
E S + S ++E + +N E DS++ + H+K D DN QDG
Sbjct: 454 EESNSTGSASSSEEDIRPKNMEADSRKLIVDA---------YHNKPIGD-QDDNDCQDG 502
Score = 70.9 bits (172), Expect = 1e-11
Identities = 63/274 (22%), Positives = 115/274 (40%), Gaps = 27/274 (9%)
Query: 39 GHSREQKASYGASTKTGN-EVVKLGRKDLKPRVEETSVIDARHKEDEEE--ADELDNKHD 95
GH+R A + G+ E D VE +S R EE EL + +
Sbjct: 223 GHARMSSAGIRSEESKGDREPTSTQDSDDSQSVEFSSRKSFRRSRVSEEDYRGELTDSNS 282
Query: 96 EQTKLDDVNGV----EDNSEHKEDSVEQESEESSQNAKTDLEGEQHTEKVDEENDNAENK 151
+T+ D E SE +ED+ E +S+E S + + +E+ E + + ++
Sbjct: 283 RETQSDSTEDTASKEESRSESQEDTAESQSQEDSPEGQD--PSSESSEEAGEPSQESSSE 340
Query: 152 ENESVEKE----NEEIKKEVEDTETGESIEEKSHLENEESKETGEISEEKSHLENEESKE 207
E V E N + + D E ES EE S N S + +EE++ E+ ES
Sbjct: 341 SQEGVTSESRGDNPDNTSQTGDQEDSESSEEDS--LNTFSSSESQSTEEQADSESNESLS 398
Query: 208 TGESSEEKSHLENEESKETGESSEEKSHLENEENKDEEKSKQENEEIKDGEKIQQENEEN 267
E S+E + + S+E +S + ++E++ E+ S+ E E+ ++
Sbjct: 399 LSEESQESAQDGDSSSQEGLQSQSASTESRSQESQSEQDSRSE------------EDSDS 446
Query: 268 KDEEKSQQENEENKDEEKSQQENELKKNEGGEKE 301
+D +S++E+ S+++ K E ++
Sbjct: 447 QDSSRSKEESNSTGSASSSEEDIRPKNMEADSRK 480
>ATRX_PONPY (Q7YQM3) Transcriptional regulator ATRX (X-linked helicase
II) (X-linked nuclear protein) (XNP)
Length = 2492
Score = 129 bits (324), Expect = 3e-29
Identities = 146/723 (20%), Positives = 306/723 (42%), Gaps = 88/723 (12%)
Query: 67 KPRVEETSVIDARHKEDEEEADELDNKHDEQTKLDDVNGVE-------------DNSEHK 113
K + ++S+I + ++ + E+ D++ +++ K G D+SE +
Sbjct: 794 KGKSAKSSIISKKKRQTQSESSNYDSELEKEIKSMSKIGAARTTKKRIPNTKDFDSSEDE 853
Query: 114 EDSVEQESEESSQNAKTDLEGEQHTEKVDEENDNAENKENESVEKEN------EEIKKEV 167
+ S + + +N KT EG + +E +N + E +V+K+ + + K+
Sbjct: 854 KHSKKGMDNQGHKNLKTSQEGSSDDAERKQERENFSSAEG-TVDKDTTIMELRDRLPKKQ 912
Query: 168 EDTETGESIEEKSHLENE----ESKETGEISEEKSHLENEESKET--GESSEEKSHLENE 221
+ + + + +++ S E E ++ E E+ HL+ + K+ G S + L+ +
Sbjct: 913 QASASTDGVDKLSGKEEGFTSLEVRKVAETKEKSKHLKTKICKKVQDGLSDITEKFLKKD 972
Query: 222 ESKETGESSEEKSHLENEENKDEEKSKQENEEIKDGEKIQQENEENKDEEKSQQENEENK 281
+S ET E +++S K E+ K+ ++ K K++Q+ E + D + E EE
Sbjct: 973 QSDETSEDDKKQS------KKGTEEKKKTSDFKKKVIKMEQQYESSSDGTEKLPEREEIC 1026
Query: 282 DEEKSQQENELKKNEGGEKETGEITEEKSKQENE-------ETSETNSKDKENEESNQNG 334
K ++ + +G EK+ +I ++ SK+++E T + +S D ++ ++NG
Sbjct: 1027 HFPKGIKQIKNGTTDG-EKKNKKIRDKTSKKKDELSDYAEKSTGKGDSCDSSEDKKSKNG 1085
Query: 335 SDAKEQV--------GENHEQDSKQGTEETNGTEGGEKEEHDKIKEDTSSDNQVQDGEKN 386
+ +E+ + S TE+ + E G ++K + + ++N
Sbjct: 1086 AYGREKKRCTLLGKSSRKRQDCSSSDTEKYSMKEDGCNSSDKRLKRIELRERRNLSSKRN 1145
Query: 387 NEAREENYSGDNASSAVVDNKSQESSNKTEEQFDKKEKNEFELESQKNSNET-TESTDST 445
+ E SG ++S A +S E + K +++ K+K E ++NS T T+ +
Sbjct: 1146 TK---EIQSGSSSSDA---EESSEDNKKKKQRTSSKKKAVIVKEKKRNSLRTSTKRKQAD 1199
Query: 446 ITQNSQGNESEKDQAQTENDTPKGSASESDEQKQEQEQNNTTKDDVQTTDTSSQNGNDTT 505
IT +S + + DQ N +GS SDEQK + N T +G++
Sbjct: 1200 ITSSSSSDIEDDDQ----NSIGEGS---SDEQKIKPVTENLVLSS--HTGFCQSSGDEAL 1250
Query: 506 EKQNE-TSEDANSKKEDSSALNTTPNNEDSKSGVAGDQADSTTTTSSSETQDGNTNHGEY 564
K T +D + + + + E+ K+ ++ D+ S S E ++G
Sbjct: 1251 SKSVPVTVDDDDDDNDPENRIAKKMLLEEIKANLSSDEDGS----SDDEPEEG------- 1299
Query: 565 KDTTNENPEKNSGQEGTQESGSSSNTFDNKDAASNKV-------QLTTTSDTSSEQKKDE 617
K T + E+N G E + +S + D++++ + +LT + S E+KK +
Sbjct: 1300 KKRTGKQNEENPGDEEAKNQVNSESDSDSEESKKPRYRHRLLRHKLTVSDGESGEEKKTK 1359
Query: 618 SS-----SAESKSESSQNDNANSGQSNTTSDESANDNKDSSQVTTSSENSAEGNSNTENN 672
++ + S D+ +S + E ++++D + T S AE N +
Sbjct: 1360 PKEHKEVKGRNRRKVSSEDSEDSDFQESGVSEEVSESEDEQRPRTRSAKKAELEENQRSY 1419
Query: 673 SDENQNDSKNNENTNDSGNTSNDANVNENQNENAAQTKTSENEGDAQNESVESKKENNES 732
+ + + + S N SN E + E + + E E + +N+ +S + +
Sbjct: 1420 KQKKKRRRIKVQEDSSSENKSNSEEEEEEKEEEEEEEEEEEEEEEDENDDSKSPGKGRKK 1479
Query: 733 AHK 735
K
Sbjct: 1480 IRK 1482
Score = 108 bits (271), Expect = 4e-23
Identities = 144/742 (19%), Positives = 288/742 (38%), Gaps = 64/742 (8%)
Query: 56 NEVVKLGRKDLKPRVEETSVIDARHKEDEEEADELDNKHDEQTKLDDVNGVEDNSEHKED 115
NE VK +K P ++ D R+ D + NK + + + V+ D+ E
Sbjct: 682 NETVKEKQKLSVPVRKK----DKRNSSDSAIDNPKPNKLPKSKQSETVDQNSDSDEMLAI 737
Query: 116 SVEQESEESSQNAKTDLEGEQHTEKVDEENDNAENKENESVEKENEEIKKEVEDTETGES 175
E S ++ TD+ K + K+++ K DT+ G+S
Sbjct: 738 LKEVSRMSHSSSSDTDINEIHTNHKTLYDLKTQAGKDDKGKRKRKSSTSGSDFDTKKGKS 797
Query: 176 IEEKSHLENEESKET-GEISEEKSHLENE--ESKETGESSEEKSHLENEESKETGESSEE 232
KS + +++ ++T E S S LE E + G + K + N +K+ S +E
Sbjct: 798 A--KSSIISKKKRQTQSESSNYDSELEKEIKSMSKIGAARTTKKRIPN--TKDFDSSEDE 853
Query: 233 KSHLENEENKDEEKSKQENEEIKDGEKIQQENEENKDEEKSQQENEENKDEEKSQQENEL 292
K + +N+ + K E D + +QE E S E +KD + + L
Sbjct: 854 KHSKKGMDNQGHKNLKTSQEGSSDDAERKQERENF-----SSAEGTVDKDTTIMELRDRL 908
Query: 293 KKNEGGEKETGEITEEKSKQEN------EETSETNSKDKENE----ESNQNG-------- 334
K + T + + K+E + +ET K K + + Q+G
Sbjct: 909 PKKQQASASTDGVDKLSGKEEGFTSLEVRKVAETKEKSKHLKTKICKKVQDGLSDITEKF 968
Query: 335 --SDAKEQVGENHEQDSKQGTEETNGTEGGEKEEHDKIKEDTSSDNQVQDGEKNNEAREE 392
D ++ E+ ++ SK+GTEE T +K+ ++ SS DG + REE
Sbjct: 969 LKKDQSDETSEDDKKQSKKGTEEKKKTSDFKKKVIKMEQQYESSS----DGTEKLPEREE 1024
Query: 393 NYSGDNASSAVVDNKSQESSNKTEEQFDKKEKNEFEL----ESQKNSNETTESTDSTITQ 448
+ N + + K ++ DK K + EL E ++ +S++ ++
Sbjct: 1025 ICHFPKGIKQI-KNGTTDGEKKNKKIRDKTSKKKDELSDYAEKSTGKGDSCDSSEDKKSK 1083
Query: 449 N-SQGNESEKDQAQTENDTPKGSASESDEQKQEQEQNNTTKDDVQTTDTSSQNGNDTTEK 507
N + G E ++ ++ + S SD +K +++ D + + + + K
Sbjct: 1084 NGAYGREKKRCTLLGKSSRKRQDCSSSDTEKYSMKEDGCNSSDKRLKRIELRERRNLSSK 1143
Query: 508 QN-------ETSEDANSKKEDSSALNTTPNNEDSKSGVAGDQADSTTTTSSSETQDGNTN 560
+N +S DA ED+ +++ K+ + ++ ++ TS+ Q T+
Sbjct: 1144 RNTKEIQSGSSSSDAEESSEDNKKKKQRTSSK-KKAVIVKEKKRNSLRTSTKRKQADITS 1202
Query: 561 HGEYKDTTNENPEKNSGQEGTQESGSSSNTFDNKDAASNKVQLTTTSDTSSEQKKDESSS 620
+ E+ ++NS EG+ + +N +S+ T +S ++ +S
Sbjct: 1203 SSS---SDIEDDDQNSIGEGSSDEQKIKPVTENLVLSSH----TGFCQSSGDEALSKSVP 1255
Query: 621 AESKSESSQNDNANSGQSNTTSDESANDNKDSSQVTTSSENSAEGNSNTENNSDENQNDS 680
+ ND N +E N S + +S + EG T ++EN D
Sbjct: 1256 VTVDDDDDDNDPENRIAKKMLLEE-IKANLSSDEDGSSDDEPEEGKKRTGKQNEENPGDE 1314
Query: 681 KNNENTNDSGNTSNDANVNENQNENAAQTKTSENEGDAQNESVESKKENNE--SAHKDVD 738
+ N ++ ++ + + K + ++G++ E KE+ E ++
Sbjct: 1315 EAKNQVNSESDSDSEESKKPRYRHRLLRHKLTVSDGESGEEKKTKPKEHKEVKGRNRRKV 1374
Query: 739 NNSNSNDQGSSDTSVTQDDKES 760
++ +S D ++ V+++ ES
Sbjct: 1375 SSEDSEDSDFQESGVSEEVSES 1396
Score = 101 bits (252), Expect = 7e-21
Identities = 139/710 (19%), Positives = 273/710 (37%), Gaps = 152/710 (21%)
Query: 62 GRKDLKPRVEETSVIDARHKEDEEEADELDNKHDEQTKL--------------------D 101
G K+LK +E S DA K++ E + D+ T + D
Sbjct: 864 GHKNLKTS-QEGSSDDAERKQERENFSSAEGTVDKDTTIMELRDRLPKKQQASASTDGVD 922
Query: 102 DVNGVEDNSEHKEDSVEQESEESSQNAKTDL------------EGEQHTEKVDE--ENDN 147
++G E+ E E++E S++ KT + E ++ DE E+D
Sbjct: 923 KLSGKEEGFTSLEVRKVAETKEKSKHLKTKICKKVQDGLSDITEKFLKKDQSDETSEDDK 982
Query: 148 AENKENESVEKENEEIKKEV-----------EDTETGESIEEKSHL-------------- 182
++K+ +K+ + KK+V + TE EE H
Sbjct: 983 KQSKKGTEEKKKTSDFKKKVIKMEQQYESSSDGTEKLPEREEICHFPKGIKQIKNGTTDG 1042
Query: 183 ENEESKETGEISEEKSHLENEESKETG-----ESSEEKSHLENEESKET------GESSE 231
E + K + S++K L + K TG +SSE+K +E G+SS
Sbjct: 1043 EKKNKKIRDKTSKKKDELSDYAEKSTGKGDSCDSSEDKKSKNGAYGREKKRCTLLGKSSR 1102
Query: 232 EKSHLENEENKD----EEKSKQENEEIKDGEKIQQENEENKDEEKSQQENEENKDEEKSQ 287
++ + + + E+ ++ +K E ++ N +K K Q + D E+S
Sbjct: 1103 KRQDCSSSDTEKYSMKEDGCNSSDKRLKRIELRERRNLSSKRNTKEIQSGSSSSDAEESS 1162
Query: 288 QENELKKNEGGEKETGEITEEK--------SKQENEETSETNSKDKENEESNQNGSDAKE 339
++N+ KK K+ I +EK +K++ + + ++S D E+++ N G + +
Sbjct: 1163 EDNKKKKQRTSSKKKAVIVKEKKRNSLRTSTKRKQADITSSSSSDIEDDDQNSIGEGSSD 1222
Query: 340 Q-----VGENHEQDSKQGTEETNGTEGGEKEEHDKIKEDTSSDNQVQDGEKNNEAREE-- 392
+ V EN S G +++G E K + +D DN ++ EE
Sbjct: 1223 EQKIKPVTENLVLSSHTGFCQSSGDEALSKSVPVTV-DDDDDDNDPENRIAKKMLLEEIK 1281
Query: 393 -NYSGDNASSAVVDNKSQESSNKTEEQFDKKEKNEFELESQKNSNETTESTDSTITQNSQ 451
N S D S+ D++ +E +T +Q + +
Sbjct: 1282 ANLSSDEDGSS--DDEPEEGKKRTGKQ----------------------------NEENP 1311
Query: 452 GNESEKDQAQTENDTPKGSASESDEQKQEQEQNNTTKDDVQTTDTSSQNGNDTTEKQNET 511
G+E K+Q +E+D S+S+E K+ + ++ + + +D S T K+++
Sbjct: 1312 GDEEAKNQVNSESD------SDSEESKKPRYRHRLLRHKLTVSDGESGEEKKTKPKEHKE 1365
Query: 512 SEDANSKKEDSSALNTTPNNEDSKSGVAGDQADS----TTTTSSSETQDGNTNHGEYKDT 567
+ N +K S + +++ +SGV+ + ++S T S++ + N YK
Sbjct: 1366 VKGRNRRKVSS---EDSEDSDFQESGVSEEVSESEDEQRPRTRSAKKAELEENQRSYKQ- 1421
Query: 568 TNENPEKNSGQEGTQESGSSSNTFDNKDAASNKVQLTTTSDTSSEQKKDESSSAESKSES 627
+K + QE SS N ++++ K E++++E E + E
Sbjct: 1422 -----KKKRRRIKVQEDSSSENKSNSEEEEEEK-----------EEEEEEEEEEEEEEED 1465
Query: 628 SQNDNANSGQSNTTSDESANDNKDSSQVTTSSENSAEGNSNTENNSDENQ 677
+D+ + G+ + D+K ++ + + E E +
Sbjct: 1466 ENDDSKSPGKGRKKIRKILKDDKLRTETQNALKEEEERRKRIAERERERE 1515
Score = 99.0 bits (245), Expect = 4e-20
Identities = 144/737 (19%), Positives = 287/737 (38%), Gaps = 74/737 (10%)
Query: 56 NEV-VKLGRKDLK--PRVEETSVIDARHKEDEEEADELDNKHDEQTKLDDVNGVEDNSEH 112
NEV + L DL+ PRV+ T + R E D + +E K V +
Sbjct: 642 NEVSLLLEESDLRRSPRVKTTPL--RRQTETNPVTSNSDEECNETVKEKQKLSVPVRKKD 699
Query: 113 KEDSVEQESEESSQNAKTDLEGEQHTEKVDEENDNAEN----------KENESVEKENEE 162
K +S + + N L + +E VD+ +D+ E + S + + E
Sbjct: 700 KRNSSDSAIDNPKPNK---LPKSKQSETVDQNSDSDEMLAILKEVSRMSHSSSSDTDINE 756
Query: 163 IK---KEVEDTETGESIEEKSHLENEESKETGEISEEKSHLENEE--SKETGESSEEKSH 217
I K + D +T ++K + + S + +K SK+ ++ E S+
Sbjct: 757 IHTNHKTLYDLKTQAGKDDKGKRKRKSSTSGSDFDTKKGKSAKSSIISKKKRQTQSESSN 816
Query: 218 LENEESKETGESSEEKSHLENEENKDEEKSKQENEEIKDGEKIQQENEENKDEEKSQQEN 277
++E KE S+ + ++ K +E+ K +K +N+ +K+ + SQ+ +
Sbjct: 817 YDSELEKEIKSMSKIGAARTTKKRIPNTKDFDSSEDEKHSKK-GMDNQGHKNLKTSQEGS 875
Query: 278 EENKDEEKSQQENELKKNEGGEKETGEITEEKSK--QENEETSETNSKDKENEESNQNGS 335
+ D E+ Q+ EG + I E + + ++ + ++ T+ DK + + S
Sbjct: 876 SD--DAERKQERENFSSAEGTVDKDTTIMELRDRLPKKQQASASTDGVDKLSGKEEGFTS 933
Query: 336 DAKEQVGENHEQDSKQGTEETNGTEGGEKEEHDK-IKEDTSSDNQVQDGEKNNEAREENY 394
+V E E+ T+ + G + +K +K+D S + D +++ + EE
Sbjct: 934 LEVRKVAETKEKSKHLKTKICKKVQDGLSDITEKFLKKDQSDETSEDDKKQSKKGTEEKK 993
Query: 395 SGDNASSAVVDNKSQ--ESSNKTEEQFDKKEKNEFELESQKNSNETT--ESTDSTITQNS 450
+ V+ + Q SS+ TE+ +++E F ++ N TT E + I +
Sbjct: 994 KTSDFKKKVIKMEQQYESSSDGTEKLPEREEICHFPKGIKQIKNGTTDGEKKNKKIRDKT 1053
Query: 451 QGNESEKDQAQTENDTPKGSASESDEQKQEQEQNNTTKDDVQTTDTSSQNGNDTTEKQNE 510
+ E E T KG + +S E K+ S+NG EK+
Sbjct: 1054 SKKKDELSD-YAEKSTGKGDSCDSSEDKK------------------SKNGAYGREKKRC 1094
Query: 511 TSEDANSKKEDSSALNTTPNNEDSKSGVAGDQADSTTTTSSSETQDGNTNHGEYKDTTNE 570
T +S+K + + T + G + D E ++ N
Sbjct: 1095 TLLGKSSRKRQDCSSSDTEKYSMKEDGC--------------NSSDKRLKRIELRERRNL 1140
Query: 571 NPEKNSGQEGTQESGSSSNTFDNKDAASNKVQLTTTSDTSSEQKKDESSSAESKSESSQN 630
+ ++N+ + Q SSS+ ++ + K Q T++ + K+ + +S + ++ Q
Sbjct: 1141 SSKRNTKE--IQSGSSSSDAEESSEDNKKKKQRTSSKKKAVIVKEKKRNSLRTSTKRKQA 1198
Query: 631 DNANSGQSNTTSDES---ANDNKDSSQVTTSSENSAEGNSNTENNSDENQNDSKNNENTN 687
D +S S+ D+ + D ++ +EN + S ++ SK+ T
Sbjct: 1199 DITSSSSSDIEDDDQNSIGEGSSDEQKIKPVTENLVLSSHTGFCQSSGDEALSKSVPVTV 1258
Query: 688 DSGNTSNDAN---VNENQNENAAQTKTSENEGDAQNESVESKKENNESAHKDVDNNSNSN 744
D + ND + E +S+ +G + +E E KK + ++ + N
Sbjct: 1259 DDDDDDNDPENRIAKKMLLEEIKANLSSDEDGSSDDEPEEGKKRTGKQNEENPGDEEAKN 1318
Query: 745 DQGSSDTSVTQDDKESR 761
S S +++ K+ R
Sbjct: 1319 QVNSESDSDSEESKKPR 1335
Score = 87.0 bits (214), Expect = 2e-16
Identities = 67/274 (24%), Positives = 128/274 (46%), Gaps = 42/274 (15%)
Query: 82 EDEEEADELDNKHDEQTKLDDVNGVEDNSEHKEDSVEQESEESSQNAKTDLEGEQHTEKV 141
+D+++ ++ +N+ ++ L+++ N ED + E EG++ T K
Sbjct: 1259 DDDDDDNDPENRIAKKMLLEEIKA---NLSSDEDGSSDDEPE---------EGKKRTGKQ 1306
Query: 142 DEEN---DNAENKENESVEKENEEIKKE------------VEDTETGESIEEKSHLENEE 186
+EEN + A+N+ N + ++EE KK V D E+GE + K +E
Sbjct: 1307 NEENPGDEEAKNQVNSESDSDSEESKKPRYRHRLLRHKLTVSDGESGEEKKTKP----KE 1362
Query: 187 SKETGEISEEKSHLENEESKETGESSEEKSHLENEESKETGESSEEKSHLENEENKDEEK 246
KE + K E+ E + ES + E+E+ + S +K+ LE + ++K
Sbjct: 1363 HKEVKGRNRRKVSSEDSEDSDFQESGVSEEVSESEDEQRPRTRSAKKAELEENQRSYKQK 1422
Query: 247 SKQENEEIK-DGEKIQQENEENKDEEKSQQENEENKDEEKSQQENELKKNEG-GEKETGE 304
K+ +++ D + N E ++EEK ++E EE ++EE+ + EN+ K+ G G K+ +
Sbjct: 1423 KKRRRIKVQEDSSSENKSNSEEEEEEKEEEEEEEEEEEEEEEDENDDSKSPGKGRKKIRK 1482
Query: 305 I---------TEEKSKQENEETSETNSKDKENEE 329
I T+ K+E E +++E E+
Sbjct: 1483 ILKDDKLRTETQNALKEEEERRKRIAEREREREK 1516
Score = 75.9 bits (185), Expect = 4e-13
Identities = 83/357 (23%), Positives = 152/357 (42%), Gaps = 59/357 (16%)
Query: 79 RHKEDEEEADELDNKHDEQTKLDDVNGVEDNSEHKEDSVEQESEESSQNAKTDLEGEQHT 138
R + D + D + D+Q + G + E K V + SS G++
Sbjct: 1195 RKQADITSSSSSDIEDDDQNSI----GEGSSDEQKIKPVTENLVLSSHTGFCQSSGDEAL 1250
Query: 139 EK-----VDEENDNAENKENESVEKENEEIKKEVEDTETGESIEEKSHLENEESKETGEI 193
K VD+++D+ + + + + EEIK + E G S +E E K TG+
Sbjct: 1251 SKSVPVTVDDDDDDNDPENRIAKKMLLEEIKANLSSDEDGSSDDEPE----EGKKRTGKQ 1306
Query: 194 SEEK---SHLENEESKETGESSEEKSH-------LENEESKETGESSEEKSHL--ENEEN 241
+EE +N+ + E+ SEE L ++ + GES EEK E++E
Sbjct: 1307 NEENPGDEEAKNQVNSESDSDSEESKKPRYRHRLLRHKLTVSDGESGEEKKTKPKEHKEV 1366
Query: 242 KDEEKSKQENEEIKDGE----KIQQENEENKDEEKSQ---------QENEENKDEEKSQ- 287
K + K +E+ +D + + +E E++DE++ + +EN+ + ++K +
Sbjct: 1367 KGRNRRKVSSEDSEDSDFQESGVSEEVSESEDEQRPRTRSAKKAELEENQRSYKQKKKRR 1426
Query: 288 ----QENELKKNEGGEKETGEITEEKSKQENEETSETNSKDKENEESNQNGSDAKEQVGE 343
QE+ +N+ +E E EE+ ++E EE E ++ EN++S G K+
Sbjct: 1427 RIKVQEDSSSENKSNSEEEEEEKEEEEEEEEEEEEE---EEDENDDSKSPGKGRKKI--R 1481
Query: 344 NHEQDSKQGTEETNGTEGGEKEEHDKIKEDTSSDNQVQDGEKNNEAREENYSGDNAS 400
+D K TE N +KE+ ++ + E+ E E ++AS
Sbjct: 1482 KILKDDKLRTETQNA-----------LKEEEERRKRIAEREREREKLREVIEIEDAS 1527
Score = 73.9 bits (180), Expect = 1e-12
Identities = 115/651 (17%), Positives = 247/651 (37%), Gaps = 44/651 (6%)
Query: 96 EQTKLDDVNGVEDNSEHKEDSVEQESEESSQNAKTDLEGEQHTEKVDEENDNAENKENES 155
EQ + ++ +SE E S S + ++ GE+ +K+D+ + +
Sbjct: 288 EQLLQQNKKKIKVDSEKSNKVYEHTSRFSPKKTSSNCNGEE--KKLDDSCSGSVTYSYSA 345
Query: 156 VEKENEEIKKEVEDTETGESIEEKSHLENEESKETGEISEEKSHLENEESKETGESSEEK 215
+ E IKK + ET ++ +++ + EI+ + L ++ ++ + +K
Sbjct: 346 LIVPKEMIKKAKKLIETTANMNSSYVKFLKQATDNSEINSA-TKLRQLKAFKSVLADIKK 404
Query: 216 SHLENEESKETGESSEEKSHLENEENKDEEKSKQENEEIKDGEKIQQENEENKDEEKSQQ 275
+HL EE + + E+N E K + E K + + E KD KS+
Sbjct: 405 AHLALEE--DLNSEFRAMDAVSKEKNTKEHKVIEAKFETKARKGEKPCALEKKDISKSEA 462
Query: 276 ENEENKDEEKSQQENELKKNEGGEKETGEITEEKSKQENEETSETNSKDKENEESNQNGS 335
+ + + + +N + + K TG ++ ++E + N+ + + + S
Sbjct: 463 KLSRKQVDSEHMYQNVPTEEQRANKSTGGEHKKSDRKEEPQYEPANTSEDLDMDIVSVPS 522
Query: 336 DAKEQVGENHE---QDSKQGTEETNGTEGGEKE-EHDKIKEDTSSDNQVQDGEKNNEARE 391
E + EN E + + +G+ G E+E E +K SS + + A+
Sbjct: 523 SVPEDIFENLETAMEVQSSVDHQGDGSSGTEQEVESSSVKLSISSKDNRGGIKSKTTAKV 582
Query: 392 ENYSGDNASSAVVDNKSQESSNKTEEQFDKKEKNEFELESQKNSNETTESTDSTITQNSQ 451
+ + N + ++ E DK L + + +
Sbjct: 583 TKELYVKLTPVSLSNSPIKGADCQEVPQDKDGYKSCGLNPK-------------LEKCGL 629
Query: 452 GNESEKDQAQTENDTPKGSASESDEQKQEQEQNNTTKDDVQTTDTSSQNGNDTTEKQNET 511
G E+ ++ EN+ ESD ++ + + + +T +S + E
Sbjct: 630 GQENSDNEHLVENEVSL-LLEESDLRRSPRVKTTPLRRQTETNPVTSNS-------DEEC 681
Query: 512 SEDANSKKEDSSALNTTPNNEDSKSGVAGDQADSTTTTSSSETQDGNTNHGEYKDTTNEN 571
+E K++ S + S S + + + + SET D N++ E E
Sbjct: 682 NETVKEKQKLSVPVRKKDKRNSSDSAIDNPKPNKLPKSKQSETVDQNSDSDEMLAILKE- 740
Query: 572 PEKNSGQEGTQESGSSSNTFDNKDAASNKVQLTTTSDTSSEQKKDESSSAESKSESSQND 631
SSS+T N+ ++K T D ++ KD+ + KS +S +D
Sbjct: 741 -------VSRMSHSSSSDTDINEIHTNHK----TLYDLKTQAGKDDKGKRKRKSSTSGSD 789
Query: 632 -NANSGQSNTTSDESANDNKDSSQVTTSSENSAEGNSNTENNSDENQNDSKNNENTNDSG 690
+ G+S +S S + S+ +++ ++ E + + + K NT D
Sbjct: 790 FDTKKGKSAKSSIISKKKRQTQSE-SSNYDSELEKEIKSMSKIGAARTTKKRIPNTKDFD 848
Query: 691 NTSNDANVNENQNENAAQTKTSENEGDAQNESVESKKENNESAHKDVDNNS 741
++ ++ + + + + + EG + + + ++EN SA VD ++
Sbjct: 849 SSEDEKHSKKGMDNQGHKNLKTSQEGSSDDAERKQERENFSSAEGTVDKDT 899
Score = 71.2 bits (173), Expect = 1e-11
Identities = 102/514 (19%), Positives = 216/514 (41%), Gaps = 84/514 (16%)
Query: 41 SREQKASYGASTKTGNEVVKLGRKDLKPRVEETSVIDARH-KEDEEEADELDNKHDEQTK 99
S ++K+ GA + LG+ K + +S + KED + + K E +
Sbjct: 1077 SEDKKSKNGAYGREKKRCTLLGKSSRKRQDCSSSDTEKYSMKEDGCNSSDKRLKRIELRE 1136
Query: 100 LDDVNGVEDNSEHKEDSVEQESEESSQNAKTDLEGEQHTEKVDEENDNAENKENESVEKE 159
+++ + E + S ++EESS++ K + +K + N S +++
Sbjct: 1137 RRNLSSKRNTKEIQSGSSSSDAEESSEDNKKKKQRTSSKKKAVIVKEKKRNSLRTSTKRK 1196
Query: 160 NEEI----KKEVEDTET-----GESIEEKSHLENEE---SKETGEISEEKSHLENEESKE 207
+I ++ED + G S E+K E S TG ++
Sbjct: 1197 QADITSSSSSDIEDDDQNSIGEGSSDEQKIKPVTENLVLSSHTGFCQSSGDEALSKSVPV 1256
Query: 208 TGESSEEKSHLENEESKETGESSEEKSHLENEENKDEEKSKQENEEIKDGEKIQQENEEN 267
T + ++ + EN +K+ E K++L ++E+ + +E ++ + ++NEEN
Sbjct: 1257 TVDDDDDDNDPENRIAKKM-LLEEIKANLSSDEDGSSDDEPEEGKK-----RTGKQNEEN 1310
Query: 268 KDEE--KSQQENEENKDEEKSQQ--------ENELKKNEGGEKETGEITEEKSKQENEET 317
+E K+Q +E + D E+S++ ++L ++G E+GE + K K+ E
Sbjct: 1311 PGDEEAKNQVNSESDSDSEESKKPRYRHRLLRHKLTVSDG---ESGEEKKTKPKEHKEVK 1367
Query: 318 SETNSK--DKENEESNQNGSDAKEQVGENHEQD------SKQGTEETNGTEGGEKEEHDK 369
K +++E+S+ S E+V E+ ++ +K+ E N +K++ +
Sbjct: 1368 GRNRRKVSSEDSEDSDFQESGVSEEVSESEDEQRPRTRSAKKAELEENQRSYKQKKKRRR 1427
Query: 370 IK--EDTSSDNQVQDGEKNNEAREENYSGDNASSAVVDNKSQESSNKTEEQFDKKEKNEF 427
IK ED+SS+N+ E+ E EE EE+ +++E
Sbjct: 1428 IKVQEDSSSENKSNSEEEEEEKEEE-----------------------EEEEEEEE---- 1460
Query: 428 ELESQKNSNETTESTDSTITQNSQGNESEKDQAQTENDTPKGSASESDEQK----QEQEQ 483
E +++ N+ ++S + + + +K + +T+N + E +E++ + + +
Sbjct: 1461 --EEEEDENDDSKSPGKGRKKIRKILKDDKLRTETQN-----ALKEEEERRKRIAERERE 1513
Query: 484 NNTTKDDVQTTDTSSQNGNDTT----EKQNETSE 513
++ ++ D S TT ++ ET E
Sbjct: 1514 REKLREVIEIEDASPTKCPITTKLVLDEDEETKE 1547
Score = 55.1 bits (131), Expect = 7e-07
Identities = 112/633 (17%), Positives = 228/633 (35%), Gaps = 78/633 (12%)
Query: 174 ESIEEKSHLENEESKETGEISEEK--SHLENEESKETGESSEEKSHLENEESKETGESSE 231
+ I+ S N+ + T S +K S+ EE K S ++ + +
Sbjct: 296 KKIKVDSEKSNKVYEHTSRFSPKKTSSNCNGEEKKLDDSCSGSVTYSYSALIVPKEMIKK 355
Query: 232 EKSHLENEENKDEE-----KSKQENEEIKDGEKIQQENEENK---DEEKSQQENEENKDE 283
K +E N + K +N EI K++Q D +K+ EE+ +
Sbjct: 356 AKKLIETTANMNSSYVKFLKQATDNSEINSATKLRQLKAFKSVLADIKKAHLALEEDLNS 415
Query: 284 EKSQQENELKKNEGGEKETGEITEEKSKQENEETSETNSKDKENEESNQNGSDAKEQVGE 343
E + K+ E + E E ++ E+ KD E+ + ++QV
Sbjct: 416 EFRAMDAVSKEKNTKEHKVIEAKFETKARKGEKPCALEKKDISKSEAKLS----RKQVDS 471
Query: 344 NHEQDSKQGTEE-TNGTEGGEKEEHDKIKE------DTSSDNQVQDGEKNNEAREENYSG 396
H + E+ N + GGE ++ D+ +E +TS D + + E+ +
Sbjct: 472 EHMYQNVPTEEQRANKSTGGEHKKSDRKEEPQYEPANTSEDLDMDIVSVPSSVPEDIFEN 531
Query: 397 DNASSAV---VDNKSQESSNKTEEQFDKKEKNEFELESQKNSNETTESTDSTITQNSQGN 453
+ V VD++ SS +E K + S+ N T + +T+
Sbjct: 532 LETAMEVQSSVDHQGDGSSGTEQEVESSSVK--LSISSKDNRGGIKSKTTAKVTKELY-- 587
Query: 454 ESEKDQAQTENDTPKGSASESDEQKQEQEQNNTTKDDVQTTDTSSQNGNDTTEKQNETS- 512
+ N KG+ + Q ++ ++ ++ +N ++ +NE S
Sbjct: 588 -VKLTPVSLSNSPIKGADCQEVPQDKDGYKSCGLNPKLEKCGLGQENSDNEHLVENEVSL 646
Query: 513 --EDANSKKEDSSALNTTPNNEDSKSGVAGDQADSTTTTSSSETQDGNTNHGEYKDTTNE 570
E+++ ++ S + TTP Q ++ TS+S+ E +T E
Sbjct: 647 LLEESDLRR--SPRVKTTPLRR---------QTETNPVTSNSDE--------ECNETVKE 687
Query: 571 NPEKNSGQEGTQESGSSSNTFDNKDAASNKVQLTTTSDTSSEQKKDESSSAESKSESSQN 630
+ + + SS + DN NK+ + S+T + + A K S +
Sbjct: 688 KQKLSVPVRKKDKRNSSDSAIDNPKP--NKLPKSKQSETVDQNSDSDEMLAILKEVSRMS 745
Query: 631 DNANSGQSNTTSDESANDNKDSSQVTTSSENSAEGNSNTENNSDENQNDSKNNENTNDSG 690
+S S+T +E ++K + T + +G ++++ + D+K ++ S
Sbjct: 746 ---HSSSSDTDINEIHTNHKTLYDLKTQAGKDDKGKRKRKSSTSGSDFDTKKGKSAKSS- 801
Query: 691 NTSNDANVNENQNENAAQTKTSENEGDAQNESVESKKENNESAHKDVDNNSNSNDQGSSD 750
K + + ++ N E +KE + + + D
Sbjct: 802 ---------------IISKKKRQTQSESSNYDSELEKEIKSMSKIGAARTTKKRIPNTKD 846
Query: 751 TSVTQDDKESRVDLGTLPESNGESHHNDVSSAE 783
++D+K S+ + + + H N +S E
Sbjct: 847 FDSSEDEKHSKKGM------DNQGHKNLKTSQE 873
Score = 36.6 bits (83), Expect = 0.26
Identities = 39/165 (23%), Positives = 63/165 (37%), Gaps = 21/165 (12%)
Query: 148 AENKENESVEKENEEIKKEVEDTETGESIEEKSHLEN--------------EESKETGEI 193
+E+K N V+K ++ + E++E S + +N E SKE G
Sbjct: 7 SESKLNTLVQKLHDFLAHSSEESEETSSPPRLAMNQNTDKISGSGSNSDMMENSKEEGTS 66
Query: 194 SEEKSHLENEESKETGESSEEKSHLENEESKETGESSEEKSHLENEENKDEEKSKQENEE 253
S EKS + S K ++E E+ E + EN EN +S +
Sbjct: 67 SSEKSKSSGSSRSKRKPSIVTKYVESDDEKPLDDETVNEDASNENSENDITMQSLPKGTV 126
Query: 254 IKDGEKIQQENEENKDEEKSQQENEENKDEEKSQQENELKKNEGG 298
I E + +E+K + E + K + EN K+ E G
Sbjct: 127 IVQPEPV-------LNEDKDDFKGPEFRSRSKMKTENLKKRGEDG 164
Score = 34.3 bits (77), Expect = 1.3
Identities = 31/134 (23%), Positives = 51/134 (37%), Gaps = 21/134 (15%)
Query: 539 AGDQADSTTTTSSSETQDGNTNHGEYKDTTNENPEKNSGQEGTQESGSSSNTFDNKDAAS 598
A ++S T + D + E + T+ P Q + SGS SN+
Sbjct: 3 AEPMSESKLNTLVQKLHDFLAHSSEESEETSSPPRLAMNQNTDKISGSGSNS-------- 54
Query: 599 NKVQLTTTSDTSSEQKKDESSSAESKSESSQNDNANSGQSNTTSDESANDNKDSSQVTTS 658
E K+E +S+ KS+SS + + S T ++D K T +
Sbjct: 55 ----------DMMENSKEEGTSSSEKSKSSGSSRSKRKPSIVTKYVESDDEKPLDDETVN 104
Query: 659 SENSAEGNSNTENN 672
+ S N N+EN+
Sbjct: 105 EDAS---NENSEND 115
Score = 32.0 bits (71), Expect = 6.5
Identities = 19/91 (20%), Positives = 43/91 (46%), Gaps = 3/91 (3%)
Query: 658 SSENSAEGNSNTENNSDENQNDSKNNENTNDSGNTSNDANVNENQNENAAQTKTSENEGD 717
SSE S E +S ++N + + + +D S + + ++ ++ + S+ +
Sbjct: 25 SSEESEETSSPPRLAMNQNTDKISGSGSNSDMMENSKEEGTSSSEKSKSSGSSRSKRKPS 84
Query: 718 AQNESVESKKE---NNESAHKDVDNNSNSND 745
+ VES E ++E+ ++D N ++ ND
Sbjct: 85 IVTKYVESDDEKPLDDETVNEDASNENSEND 115
>ATRX_HUMAN (P46100) Transcriptional regulator ATRX (X-linked helicase
II) (X-linked nuclear protein) (XNP) (Znf-HX)
Length = 2492
Score = 129 bits (324), Expect = 3e-29
Identities = 143/722 (19%), Positives = 311/722 (42%), Gaps = 86/722 (11%)
Query: 67 KPRVEETSVIDARHKEDEEEADELDNKHDEQTK-LDDVNGVEDNSEHKEDSVEQESEESS 125
K + ++S+I + ++ + E+ D++ +++ K + + + ++ + +S E
Sbjct: 794 KGKSAKSSIISKKKRQTQSESSNYDSELEKEIKSMSKIGAARTTKKRIPNTKDFDSSEDE 853
Query: 126 QNAKTDLEGEQHTE-KVDEE--NDNAENKENE--------SVEKEN------EEIKKEVE 168
+++K ++ + H K +E +D+AE K+ +V+K+ + + K+ +
Sbjct: 854 KHSKKGMDNQGHKNLKTSQEGSSDDAERKQERETFSSAEGTVDKDTTIMELRDRLPKKQQ 913
Query: 169 DTETGESIEEKSHLENE----ESKETGEISEEKSHLENEESKET--GESSEEKSHLENEE 222
+ + + +++ S E E ++ E E+ HL+ + K+ G S + L+ ++
Sbjct: 914 ASASTDGVDKLSGKEQSFTSLEVRKVAETKEKSKHLKTKTCKKVQDGLSDIAEKFLKKDQ 973
Query: 223 SKETGESSEEKSHLENEENKDEEKSKQENEEIKDGEKIQQENEENKDEEKSQQENEENKD 282
S ET E +++S K E+ K+ ++ K K++Q+ E + D + E EE
Sbjct: 974 SDETSEDDKKQS------KKGTEEKKKPSDFKKKVIKMEQQYESSSDGTEKLPEREEICH 1027
Query: 283 EEKSQQENELKKNEGGEKETGEITEEKSKQENE-------ETSETNSKDKENEESNQNGS 335
K ++ + +G EK++ +I ++ SK+++E T + +S D ++ ++NG+
Sbjct: 1028 FPKGIKQIKNGTTDG-EKKSKKIRDKTSKKKDELSDYAEKSTGKGDSCDSSEDKKSKNGA 1086
Query: 336 DAKEQV--------GENHEQDSKQGTEETNGTEGGEKEEHDKIKEDTSSDNQVQDGEKNN 387
+E+ + S TE+ + E G ++K + + ++N
Sbjct: 1087 YGREKKRCKLLGKSSRKRQDCSSSDTEKYSMKEDGCNSSDKRLKRIELRERRNLSSKRNT 1146
Query: 388 EAREENYSGDNASSAVVDNKSQESSNKTEEQFDKKEKNEFELESQKNSNET-TESTDSTI 446
+ E SG ++S A +S E + K +++ K+K E ++NS T T+ + I
Sbjct: 1147 K---EIQSGSSSSDA---EESSEDNKKKKQRTSSKKKAVIVKEKKRNSLRTSTKRKQADI 1200
Query: 447 TQNSQGNESEKDQAQTENDTPKGSASESDEQKQEQEQNNTTKDDVQTTDTSSQNGNDTTE 506
T +S + + DQ N +GS SDEQK + N T +G++
Sbjct: 1201 TSSSSSDIEDDDQ----NSIGEGS---SDEQKIKPVTENLVLSS--HTGFCQSSGDEALS 1251
Query: 507 KQNE-TSEDANSKKEDSSALNTTPNNEDSKSGVAGDQADSTTTTSSSETQDGNTNHGEYK 565
K T +D + + + + E+ K+ ++ D+ S S E ++G K
Sbjct: 1252 KSVPVTVDDDDDDNDPENRIAKKMLLEEIKANLSSDEDGS----SDDEPEEG-------K 1300
Query: 566 DTTNENPEKNSGQEGTQESGSSSNTFDNKDAASNKV-------QLTTTSDTSSEQKKDES 618
T + E+N G E + +S + D++++ + +LT + S E+KK +
Sbjct: 1301 KRTGKQNEENPGDEEAKNQVNSESDSDSEESKKPRYRHRLLRHKLTVSDGESGEEKKTKP 1360
Query: 619 S-----SAESKSESSQNDNANSGQSNTTSDESANDNKDSSQVTTSSENSAEGNSNTENNS 673
++ + S D+ +S + E ++++D + T S AE N +
Sbjct: 1361 KEHKEVKGRNRRKVSSEDSEDSDFQESGVSEEVSESEDEQRPRTRSAKKAELEENQRSYK 1420
Query: 674 DENQNDSKNNENTNDSGNTSNDANVNENQNENAAQTKTSENEGDAQNESVESKKENNESA 733
+ + + + S N SN E + E + + E E + +N+ +S + +
Sbjct: 1421 QKKKRRRIKVQEDSSSENKSNSEEEEEEKEEEEEEEEEEEEEEEDENDDSKSPGKGRKKI 1480
Query: 734 HK 735
K
Sbjct: 1481 RK 1482
Score = 106 bits (265), Expect = 2e-22
Identities = 138/726 (19%), Positives = 285/726 (39%), Gaps = 63/726 (8%)
Query: 76 IDARHKEDEEEADE-LDN-KHDEQTKLDDVNGVEDNSEHKE-----DSVEQESEESSQNA 128
+ R K+ +D +DN K ++ K V+ NS+ E V + S SS +
Sbjct: 693 VPVRKKDKRNSSDSAIDNPKPNKLPKSKQSETVDQNSDSDEMLAILKGVSRMSHSSSSD- 751
Query: 129 KTDLEGEQHTEKVDEENDNAENKENESVEKENEEIKKEVEDTETGESIEEKSHLENEESK 188
TD+ K + K+++ K DT+ G+S KS + +++ +
Sbjct: 752 -TDINEIHTNHKTLYDLKTQAGKDDKGKRKRKSSTSGSDFDTKKGKSA--KSSIISKKKR 808
Query: 189 ET-GEISEEKSHLENE--ESKETGESSEEKSHLENEESKETGESSEEKSHLENEENKDEE 245
+T E S S LE E + G + K + N +K+ S +EK + +N+ +
Sbjct: 809 QTQSESSNYDSELEKEIKSMSKIGAARTTKKRIPN--TKDFDSSEDEKHSKKGMDNQGHK 866
Query: 246 KSKQENEEIKDGEKIQQENEE--------NKDEEKSQQENEENKDEEKSQQENELKKNEG 297
K E D + +QE E +KD + + K ++ S + + K G
Sbjct: 867 NLKTSQEGSSDDAERKQERETFSSAEGTVDKDTTIMELRDRLPKKQQASASTDGVDKLSG 926
Query: 298 GEKETGEI-------TEEKSKQENEETSETNSKDKENEESNQNGSDAKEQVGENHEQDSK 350
E+ + T+EKSK +T + + D ++ E+ ++ SK
Sbjct: 927 KEQSFTSLEVRKVAETKEKSKHLKTKTCKKVQDGLSDIAEKFLKKDQSDETSEDDKKQSK 986
Query: 351 QGTEETNGTEGGEKEEHDKIKEDTSSDNQVQDGEKNNEAREENYSGDNASSAV--VDNKS 408
+GTEE +K+ D K+ + Q + E E + + + N +
Sbjct: 987 KGTEE-------KKKPSDFKKKVIKMEQQYESSSDGTEKLPEREEICHFPKGIKQIKNGT 1039
Query: 409 QESSNKTEEQFDKKEKNEFEL----ESQKNSNETTESTDSTITQN-SQGNESEKDQAQTE 463
+ K+++ DK K + EL E ++ +S++ ++N + G E ++ + +
Sbjct: 1040 TDGEKKSKKIRDKTSKKKDELSDYAEKSTGKGDSCDSSEDKKSKNGAYGREKKRCKLLGK 1099
Query: 464 NDTPKGSASESDEQKQEQEQNNTTKDDVQTTDTSSQNGNDTTEKQN-------ETSEDAN 516
+ + S SD +K +++ D + + + + K+N +S DA
Sbjct: 1100 SSRKRQDCSSSDTEKYSMKEDGCNSSDKRLKRIELRERRNLSSKRNTKEIQSGSSSSDAE 1159
Query: 517 SKKEDSSALNTTPNNEDSKSGVAGDQADSTTTTSSSETQDGNTNHGEYKDTTNENPEKNS 576
ED+ +++ K+ + ++ ++ TS+ Q T+ + E+ ++NS
Sbjct: 1160 ESSEDNKKKKQRTSSK-KKAVIVKEKKRNSLRTSTKRKQADITSSSS---SDIEDDDQNS 1215
Query: 577 GQEGTQESGSSSNTFDNKDAASNKVQLTTTSDTSSEQKKDESSSAESKSESSQNDNANSG 636
EG+ + +N +S+ T +S ++ +S + ND N
Sbjct: 1216 IGEGSSDEQKIKPVTENLVLSSH----TGFCQSSGDEALSKSVPVTVDDDDDDNDPENRI 1271
Query: 637 QSNTTSDESANDNKDSSQVTTSSENSAEGNSNTENNSDENQNDSKNNENTNDSGNTSNDA 696
+E N S + +S + EG T ++EN D + N ++ ++
Sbjct: 1272 AKKMLLEE-IKANLSSDEDGSSDDEPEEGKKRTGKQNEENPGDEEAKNQVNSESDSDSEE 1330
Query: 697 NVNENQNENAAQTKTSENEGDAQNESVESKKENNE--SAHKDVDNNSNSNDQGSSDTSVT 754
+ + K + ++G++ E KE+ E ++ ++ +S D ++ V+
Sbjct: 1331 SKKPRYRHRLLRHKLTVSDGESGEEKKTKPKEHKEVKGRNRRKVSSEDSEDSDFQESGVS 1390
Query: 755 QDDKES 760
++ ES
Sbjct: 1391 EEVSES 1396
Score = 101 bits (252), Expect = 7e-21
Identities = 123/661 (18%), Positives = 269/661 (40%), Gaps = 92/661 (13%)
Query: 50 ASTKTGNEVVKLGRKDLKPRVEETSVIDARHKEDEEEADELDNKHDEQTKLDDVNGVEDN 109
AS T G++ +E V + + K + D + + + +D
Sbjct: 914 ASASTDGVDKLSGKEQSFTSLEVRKVAETKEKSKHLKTKTCKKVQDGLSDIAEKFLKKDQ 973
Query: 110 SEHKEDSVEQESEESSQNAKTDLEGEQHTEKVDEENDNAENKENESVEKEN-----EEIK 164
S+ + +++S++ ++ K + ++ K++++ +++ + + E+E + IK
Sbjct: 974 SDETSEDDKKQSKKGTEEKKKPSDFKKKVIKMEQQYESSSDGTEKLPEREEICHFPKGIK 1033
Query: 165 KEVEDTETGESIEEKSHLENEESKETGEISE--EKSHLENE--ESKETGESSEEKSHLEN 220
+ T GE +K + ++ SK+ E+S+ EKS + + +S E +S E
Sbjct: 1034 QIKNGTTDGEKKSKK--IRDKTSKKKDELSDYAEKSTGKGDSCDSSEDKKSKNGAYGREK 1091
Query: 221 EESKETGESSEEKSHLENEENKD----EEKSKQENEEIKDGEKIQQENEENKDEEKSQQE 276
+ K G+SS ++ + + + E+ ++ +K E ++ N +K K Q
Sbjct: 1092 KRCKLLGKSSRKRQDCSSSDTEKYSMKEDGCNSSDKRLKRIELRERRNLSSKRNTKEIQS 1151
Query: 277 NEENKDEEKSQQENELKKNEGGEKETGEITEEK--------SKQENEETSETNSKDKENE 328
+ D E+S ++N+ KK K+ I +EK +K++ + + ++S D E++
Sbjct: 1152 GSSSSDAEESSEDNKKKKQRTSSKKKAVIVKEKKRNSLRTSTKRKQADITSSSSSDIEDD 1211
Query: 329 ESNQNGSDAKEQ-----VGENHEQDSKQGTEETNGTEGGEKEEHDKIKEDTSSDNQVQDG 383
+ N G + ++ V EN S G +++G E K + +D DN ++
Sbjct: 1212 DQNSIGEGSSDEQKIKPVTENLVLSSHTGFCQSSGDEALSKSVPVTV-DDDDDDNDPENR 1270
Query: 384 EKNNEAREE---NYSGDNASSAVVDNKSQESSNKTEEQFDKKEKNEFELESQKNSNETTE 440
EE N S D S+ D++ +E +T +Q
Sbjct: 1271 IAKKMLLEEIKANLSSDEDGSS--DDEPEEGKKRTGKQ---------------------- 1306
Query: 441 STDSTITQNSQGNESEKDQAQTENDTPKGSASESDEQKQEQEQNNTTKDDVQTTDTSSQN 500
+ + G+E K+Q +E+D S+S+E K+ + ++ + + +D S
Sbjct: 1307 ------NEENPGDEEAKNQVNSESD------SDSEESKKPRYRHRLLRHKLTVSDGESGE 1354
Query: 501 GNDTTEKQNETSEDANSKKEDSSALNTTPNNEDSKSGVAGDQADS----TTTTSSSETQD 556
T K+++ + N +K S + +++ +SGV+ + ++S T S++ +
Sbjct: 1355 EKKTKPKEHKEVKGRNRRKVSS---EDSEDSDFQESGVSEEVSESEDEQRPRTRSAKKAE 1411
Query: 557 GNTNHGEYKDTTNENPEKNSGQEGTQESGSSSNTFDNKDAASNKVQLTTTSDTSSEQKKD 616
N YK +K + QE SS N ++++ K E++++
Sbjct: 1412 LEENQRSYKQ------KKKRRRIKVQEDSSSENKSNSEEEEEEK-----------EEEEE 1454
Query: 617 ESSSAESKSESSQNDNANSGQSNTTSDESANDNKDSSQVTTSSENSAEGNSNTENNSDEN 676
E E + E +D+ + G+ + D+K ++ + + E E
Sbjct: 1455 EEEEEEEEEEDENDDSKSPGKGRKKIRKILKDDKLRTETQNALKEEEERRKRIAERERER 1514
Query: 677 Q 677
+
Sbjct: 1515 E 1515
Score = 98.2 bits (243), Expect = 7e-20
Identities = 144/737 (19%), Positives = 294/737 (39%), Gaps = 74/737 (10%)
Query: 56 NEV-VKLGRKDLK--PRVEETSVIDARHKEDEEEADELDNKHDEQTKLDDVNGVEDNSEH 112
NEV + L DL+ PRV+ T + R E D + +E K V +
Sbjct: 642 NEVSLLLEESDLRRSPRVKTTPL--RRPTETNPVTSNSDEECNETVKEKQKLSVPVRKKD 699
Query: 113 KEDSVEQESEESSQNAKTDLEGEQHTEKVDEENDNAEN----------KENESVEKENEE 162
K +S + + N L + +E VD+ +D+ E + S + + E
Sbjct: 700 KRNSSDSAIDNPKPNK---LPKSKQSETVDQNSDSDEMLAILKGVSRMSHSSSSDTDINE 756
Query: 163 IK---KEVEDTETGESIEEKSHLENEESKETGEISEEKSHLENEE--SKETGESSEEKSH 217
I K + D +T ++K + + S + +K SK+ ++ E S+
Sbjct: 757 IHTNHKTLYDLKTQAGKDDKGKRKRKSSTSGSDFDTKKGKSAKSSIISKKKRQTQSESSN 816
Query: 218 LENEESKETGESSEEKSHLENEENKDEEKSKQENEEIKDGEKIQQENEENKDEEKSQQEN 277
++E KE S+ + ++ K +E+ K +K +N+ +K+ + SQ+ +
Sbjct: 817 YDSELEKEIKSMSKIGAARTTKKRIPNTKDFDSSEDEKHSKK-GMDNQGHKNLKTSQEGS 875
Query: 278 EENKDEEKSQQENELKKNEGGEKETGEITEEKSK--QENEETSETNSKDKENEESNQNGS 335
+ D E+ Q+ EG + I E + + ++ + ++ T+ DK + + S
Sbjct: 876 SD--DAERKQERETFSSAEGTVDKDTTIMELRDRLPKKQQASASTDGVDKLSGKEQSFTS 933
Query: 336 DAKEQVGENHEQDSKQGTEETNGTEGGEKEEHDK-IKEDTSSDNQVQDGEKNNEAREENY 394
+V E E+ T+ + G + +K +K+D S + D +++ + EE
Sbjct: 934 LEVRKVAETKEKSKHLKTKTCKKVQDGLSDIAEKFLKKDQSDETSEDDKKQSKKGTEEKK 993
Query: 395 SGDNASSAVVDNKSQ--ESSNKTEEQFDKKEKNEFELESQKNSNETTESTD-STITQNSQ 451
+ V+ + Q SS+ TE+ +++E F ++ N TT+ S ++
Sbjct: 994 KPSDFKKKVIKMEQQYESSSDGTEKLPEREEICHFPKGIKQIKNGTTDGEKKSKKIRDKT 1053
Query: 452 GNESEKDQAQTENDTPKGSASESDEQKQEQEQNNTTKDDVQTTDTSSQNGNDTTEKQN-E 510
+ ++ E T KG + +S E K+ S+NG EK+ +
Sbjct: 1054 SKKKDELSDYAEKSTGKGDSCDSSEDKK------------------SKNGAYGREKKRCK 1095
Query: 511 TSEDANSKKEDSSALNTTPNNEDSKSGVAGDQADSTTTTSSSETQDGNTNHGEYKDTTNE 570
++ K++D S+ +T K + D +S+ D E ++ N
Sbjct: 1096 LLGKSSRKRQDCSSSDT------EKYSMKEDGCNSS---------DKRLKRIELRERRNL 1140
Query: 571 NPEKNSGQEGTQESGSSSNTFDNKDAASNKVQLTTTSDTSSEQKKDESSSAESKSESSQN 630
+ ++N+ + Q SSS+ ++ + K Q T++ + K+ + +S + ++ Q
Sbjct: 1141 SSKRNTKE--IQSGSSSSDAEESSEDNKKKKQRTSSKKKAVIVKEKKRNSLRTSTKRKQA 1198
Query: 631 DNANSGQSNTTSDES---ANDNKDSSQVTTSSENSAEGNSNTENNSDENQNDSKNNENTN 687
D +S S+ D+ + D ++ +EN + S ++ SK+ T
Sbjct: 1199 DITSSSSSDIEDDDQNSIGEGSSDEQKIKPVTENLVLSSHTGFCQSSGDEALSKSVPVTV 1258
Query: 688 DSGNTSNDAN---VNENQNENAAQTKTSENEGDAQNESVESKKENNESAHKDVDNNSNSN 744
D + ND + E +S+ +G + +E E KK + ++ + N
Sbjct: 1259 DDDDDDNDPENRIAKKMLLEEIKANLSSDEDGSSDDEPEEGKKRTGKQNEENPGDEEAKN 1318
Query: 745 DQGSSDTSVTQDDKESR 761
S S +++ K+ R
Sbjct: 1319 QVNSESDSDSEESKKPR 1335
Score = 93.2 bits (230), Expect = 2e-18
Identities = 156/803 (19%), Positives = 319/803 (39%), Gaps = 119/803 (14%)
Query: 63 RKDLKP-RVEETSVIDARHKEDEEEADELDNKHDEQTKLDDVNGVEDNSEHKEDSVEQES 121
RK KP +E+ + + K ++ D ++ H + EHK+ ++E
Sbjct: 444 RKGEKPCALEKKDISKSEAKLSRKQVDS-EHMHQNVPTEEQRTNKSTGGEHKKSDRKEEP 502
Query: 122 EESSQNAKTDLEGEQHTEKVDEENDNAENKE-----NESVEKENE---EIKKEVEDTETG 173
+ N DL+ + + D EN E SV+ + + ++EVE +
Sbjct: 503 QYEPANTSEDLDMDIVSVPSSVPEDIFENLETAMEVQSSVDHQGDGSSGTEQEVESSSVK 562
Query: 174 ESIEEKSHLENEESKETGEISEE-----------KSHLENEESKETGESSE-EKSHLENE 221
+I K + +SK T ++++E S ++ + +E + + KS N
Sbjct: 563 LNISSKDNRGGIKSKTTAKVTKELYVKLTPVSLPNSPIKGADCQEVPQDKDGYKSCGLNP 622
Query: 222 ESKETG---ESSEEKSHLENEENKDEEKSKQENEEIKDGEKIQQENEENKDEEKSQQENE 278
+ ++ G E+S+ + +ENE + E+S +++ E N S +E
Sbjct: 623 KLEKCGLGQENSDNEHLVENEVSLLLEESDLRRSPRVKTTPLRRPTETNPVTSNSDEECN 682
Query: 279 ENKDEEKSQQENELKKNEGGEKETGEITEEKSKQENEETSETNSKDKENEE--------- 329
E E++ KK++ ++ + +K + SET ++ +++E
Sbjct: 683 ETVKEKQKLSVPVRKKDKRNSSDSAIDNPKPNKLPKSKQSETVDQNSDSDEMLAILKGVS 742
Query: 330 --SNQNGSDAK-EQVGENHEQDSKQGTEETNGTEGGEKEEHDKIKEDTSSDNQVQDGEKN 386
S+ + SD ++ NH+ T T+ G K++ K K +S+ D +K
Sbjct: 743 RMSHSSSSDTDINEIHTNHK------TLYDLKTQAG-KDDKGKRKRKSSTSGSDFDTKK- 794
Query: 387 NEAREENYSGDNASSAVVDNKSQESSNKTEEQFDKKEKNEFELESQKNSNETTESTDSTI 446
G +A S+++ K +++ +++ +D + + E + S+ + TT+
Sbjct: 795 ---------GKSAKSSIISKKKRQTQSES-SNYDSELEKEIKSMSKIGAARTTKKRIPN- 843
Query: 447 TQNSQGNESEK-------DQAQTENDTPKGSASESDEQKQEQEQNNTTKDDVQTTDTSSQ 499
T++ +E EK +Q T + +S+ E+KQE+E ++ + V DT+
Sbjct: 844 TKDFDSSEDEKHSKKGMDNQGHKNLKTSQEGSSDDAERKQERETFSSAEGTVD-KDTTIM 902
Query: 500 NGNDTTEKQNETSEDANSKKEDSSALNTTPNNEDSKSGVAGDQADSTTTTSSSETQDGNT 559
D K+ + S + + S + + E K +++ T + + QDG +
Sbjct: 903 ELRDRLPKKQQASASTDGVDKLSGKEQSFTSLEVRKVAETKEKSKHLKTKTCKKVQDGLS 962
Query: 560 NHGE---YKDTTNENPE--KNSGQEGTQESGSSSNTFDNKDAASNKVQLTTTSDTSS--- 611
+ E KD ++E E K ++GT+E S+ K + Q ++SD +
Sbjct: 963 DIAEKFLKKDQSDETSEDDKKQSKKGTEEKKKPSDF--KKKVIKMEQQYESSSDGTEKLP 1020
Query: 612 ------------EQKKDESSSAESKSESSQNDNANSGQSNTTSDESANDNKDS--SQVTT 657
+Q K+ ++ E KS+ ++ + + E + DS S
Sbjct: 1021 EREEICHFPKGIKQIKNGTTDGEKKSKKIRDKTSKKKDELSDYAEKSTGKGDSCDSSEDK 1080
Query: 658 SSENSAEG---------NSNTENNSDENQNDSKNNENTNDSGNTSND----------ANV 698
S+N A G ++ D + +D++ D N+S+ N+
Sbjct: 1081 KSKNGAYGREKKRCKLLGKSSRKRQDCSSSDTEKYSMKEDGCNSSDKRLKRIELRERRNL 1140
Query: 699 NENQNENAAQTKTSENEGDAQNESVESKKENNESAHKDV---DNNSNS---------NDQ 746
+ +N Q+ +S ++ + +E + KK+ S K V + NS D
Sbjct: 1141 SSKRNTKEIQSGSSSSDAEESSEDNKKKKQRTSSKKKAVIVKEKKRNSLRTSTKRKQADI 1200
Query: 747 GSSDTSVTQDDKESRVDLGTLPE 769
SS +S +DD ++ + G+ E
Sbjct: 1201 TSSSSSDIEDDDQNSIGEGSSDE 1223
Score = 87.0 bits (214), Expect = 2e-16
Identities = 67/274 (24%), Positives = 128/274 (46%), Gaps = 42/274 (15%)
Query: 82 EDEEEADELDNKHDEQTKLDDVNGVEDNSEHKEDSVEQESEESSQNAKTDLEGEQHTEKV 141
+D+++ ++ +N+ ++ L+++ N ED + E EG++ T K
Sbjct: 1259 DDDDDDNDPENRIAKKMLLEEIKA---NLSSDEDGSSDDEPE---------EGKKRTGKQ 1306
Query: 142 DEEN---DNAENKENESVEKENEEIKKE------------VEDTETGESIEEKSHLENEE 186
+EEN + A+N+ N + ++EE KK V D E+GE + K +E
Sbjct: 1307 NEENPGDEEAKNQVNSESDSDSEESKKPRYRHRLLRHKLTVSDGESGEEKKTKP----KE 1362
Query: 187 SKETGEISEEKSHLENEESKETGESSEEKSHLENEESKETGESSEEKSHLENEENKDEEK 246
KE + K E+ E + ES + E+E+ + S +K+ LE + ++K
Sbjct: 1363 HKEVKGRNRRKVSSEDSEDSDFQESGVSEEVSESEDEQRPRTRSAKKAELEENQRSYKQK 1422
Query: 247 SKQENEEIK-DGEKIQQENEENKDEEKSQQENEENKDEEKSQQENELKKNEG-GEKETGE 304
K+ +++ D + N E ++EEK ++E EE ++EE+ + EN+ K+ G G K+ +
Sbjct: 1423 KKRRRIKVQEDSSSENKSNSEEEEEEKEEEEEEEEEEEEEEEDENDDSKSPGKGRKKIRK 1482
Query: 305 I---------TEEKSKQENEETSETNSKDKENEE 329
I T+ K+E E +++E E+
Sbjct: 1483 ILKDDKLRTETQNALKEEEERRKRIAEREREREK 1516
Score = 77.4 bits (189), Expect = 1e-13
Identities = 127/708 (17%), Positives = 265/708 (36%), Gaps = 39/708 (5%)
Query: 96 EQTKLDDVNGVEDNSEHKEDSVEQESEESSQNAKTDLEGEQHTEKVDEENDNAENKENES 155
EQ + ++ +SE E S S + ++ GE+ +K+D+ + +
Sbjct: 288 EQLLQQNKKKIKVDSEKSNKVYEHTSRFSPKKTSSNCNGEE--KKLDDSCSGSVTYSYSA 345
Query: 156 VEKENEEIKKEVEDTETGESIEEKSHLENEESKETGEISEEKSHLENEESKETGESSEEK 215
+ E IKK + ET ++ +++ + EIS + L ++ ++ + +K
Sbjct: 346 LIVPKEMIKKAKKLIETTANMNSSYVKFLKQATDNSEISSA-TKLRQLKAFKSVLADIKK 404
Query: 216 SHLENEESKETGESSEEKSHLENEENKDEEKSKQENEEIKDGEKIQQENEENKDEEKSQQ 275
+HL EE + + E+N E K E K + + E KD KS+
Sbjct: 405 AHLALEE--DLNSEFRAMDAVNKEKNTKEHKVIDAKFETKARKGEKPCALEKKDISKSEA 462
Query: 276 ENEENKDEEKSQQENELKKNEGGEKETGEITEEKSKQENEETSETNSKDKENEESNQNGS 335
+ + + + +N + + K TG ++ ++E + N+ + + + S
Sbjct: 463 KLSRKQVDSEHMHQNVPTEEQRTNKSTGGEHKKSDRKEEPQYEPANTSEDLDMDIVSVPS 522
Query: 336 DAKEQVGENHE---QDSKQGTEETNGTEGGEKE-EHDKIKEDTSSDNQVQDGEKNNEARE 391
E + EN E + + +G+ G E+E E +K + SS + + A+
Sbjct: 523 SVPEDIFENLETAMEVQSSVDHQGDGSSGTEQEVESSSVKLNISSKDNRGGIKSKTTAKV 582
Query: 392 ENYSGDNASSAVVDNKSQESSNKTEEQFDKKEKNEFEL--ESQKNSNETTESTDSTITQN 449
+ + N + ++ E DK L + +K S + + +N
Sbjct: 583 TKELYVKLTPVSLPNSPIKGADCQEVPQDKDGYKSCGLNPKLEKCGLGQENSDNEHLVEN 642
Query: 450 SQG---NESEKDQAQTENDTPKGSASESD--EQKQEQEQNNTTKD----DVQTTDTSSQN 500
ES+ ++ TP +E++ ++E N T K+ V +N
Sbjct: 643 EVSLLLEESDLRRSPRVKTTPLRRPTETNPVTSNSDEECNETVKEKQKLSVPVRKKDKRN 702
Query: 501 GNDTTEKQNETSEDANSKKEDSSALNTTPNNEDSKSGVA---GDQADSTTTTSSSETQDG 557
+D+ + ++ SK+ + T N DS +A G S +++S ++ +
Sbjct: 703 SSDSAIDNPKPNKLPKSKQSE-----TVDQNSDSDEMLAILKGVSRMSHSSSSDTDINEI 757
Query: 558 NTNHGEYKDTTNENPEKNSGQEGTQESGSSSNTFDNKDAASNKVQLTTTSDTSSEQKKDE 617
+TNH D + + + G+ ++S +S + FD K S K + + Q + E
Sbjct: 758 HTNHKTLYDLKTQAGKDDKGKR-KRKSSTSGSDFDTKKGKSAKSSIIS---KKKRQTQSE 813
Query: 618 SSSAESKSESSQNDNANSGQSNTTSDESAN-----DNKDSSQVTTSSENSAEGNSNT--E 670
SS+ +S+ E + G + TT N ++D +N N T E
Sbjct: 814 SSNYDSELEKEIKSMSKIGAARTTKKRIPNTKDFDSSEDEKHSKKGMDNQGHKNLKTSQE 873
Query: 671 NNSDENQNDSKNNENTNDSGNTSNDANVNENQNENAAQTKTSENEGDAQNESVESKKENN 730
+SD+ + + ++ G D + E ++ + + S + S + + +
Sbjct: 874 GSSDDAERKQERETFSSAEGTVDKDTTIMELRDRLPKKQQASASTDGVDKLSGKEQSFTS 933
Query: 731 ESAHKDVDNNSNSNDQGSSDTSVTQDDKESRVDLGTLPESNGESHHND 778
K + S + QD + + + E+ +D
Sbjct: 934 LEVRKVAETKEKSKHLKTKTCKKVQDGLSDIAEKFLKKDQSDETSEDD 981
Score = 75.9 bits (185), Expect = 4e-13
Identities = 83/357 (23%), Positives = 152/357 (42%), Gaps = 59/357 (16%)
Query: 79 RHKEDEEEADELDNKHDEQTKLDDVNGVEDNSEHKEDSVEQESEESSQNAKTDLEGEQHT 138
R + D + D + D+Q + G + E K V + SS G++
Sbjct: 1195 RKQADITSSSSSDIEDDDQNSI----GEGSSDEQKIKPVTENLVLSSHTGFCQSSGDEAL 1250
Query: 139 EK-----VDEENDNAENKENESVEKENEEIKKEVEDTETGESIEEKSHLENEESKETGEI 193
K VD+++D+ + + + + EEIK + E G S +E E K TG+
Sbjct: 1251 SKSVPVTVDDDDDDNDPENRIAKKMLLEEIKANLSSDEDGSSDDEPE----EGKKRTGKQ 1306
Query: 194 SEEK---SHLENEESKETGESSEEKSH-------LENEESKETGESSEEKSHL--ENEEN 241
+EE +N+ + E+ SEE L ++ + GES EEK E++E
Sbjct: 1307 NEENPGDEEAKNQVNSESDSDSEESKKPRYRHRLLRHKLTVSDGESGEEKKTKPKEHKEV 1366
Query: 242 KDEEKSKQENEEIKDGE----KIQQENEENKDEEKSQ---------QENEENKDEEKSQ- 287
K + K +E+ +D + + +E E++DE++ + +EN+ + ++K +
Sbjct: 1367 KGRNRRKVSSEDSEDSDFQESGVSEEVSESEDEQRPRTRSAKKAELEENQRSYKQKKKRR 1426
Query: 288 ----QENELKKNEGGEKETGEITEEKSKQENEETSETNSKDKENEESNQNGSDAKEQVGE 343
QE+ +N+ +E E EE+ ++E EE E ++ EN++S G K+
Sbjct: 1427 RIKVQEDSSSENKSNSEEEEEEKEEEEEEEEEEEEE---EEDENDDSKSPGKGRKKI--R 1481
Query: 344 NHEQDSKQGTEETNGTEGGEKEEHDKIKEDTSSDNQVQDGEKNNEAREENYSGDNAS 400
+D K TE N +KE+ ++ + E+ E E ++AS
Sbjct: 1482 KILKDDKLRTETQNA-----------LKEEEERRKRIAEREREREKLREVIEIEDAS 1527
Score = 70.5 bits (171), Expect = 2e-11
Identities = 102/514 (19%), Positives = 216/514 (41%), Gaps = 84/514 (16%)
Query: 41 SREQKASYGASTKTGNEVVKLGRKDLKPRVEETSVIDARH-KEDEEEADELDNKHDEQTK 99
S ++K+ GA + LG+ K + +S + KED + + K E +
Sbjct: 1077 SEDKKSKNGAYGREKKRCKLLGKSSRKRQDCSSSDTEKYSMKEDGCNSSDKRLKRIELRE 1136
Query: 100 LDDVNGVEDNSEHKEDSVEQESEESSQNAKTDLEGEQHTEKVDEENDNAENKENESVEKE 159
+++ + E + S ++EESS++ K + +K + N S +++
Sbjct: 1137 RRNLSSKRNTKEIQSGSSSSDAEESSEDNKKKKQRTSSKKKAVIVKEKKRNSLRTSTKRK 1196
Query: 160 NEEI----KKEVEDTET-----GESIEEKSHLENEE---SKETGEISEEKSHLENEESKE 207
+I ++ED + G S E+K E S TG ++
Sbjct: 1197 QADITSSSSSDIEDDDQNSIGEGSSDEQKIKPVTENLVLSSHTGFCQSSGDEALSKSVPV 1256
Query: 208 TGESSEEKSHLENEESKETGESSEEKSHLENEENKDEEKSKQENEEIKDGEKIQQENEEN 267
T + ++ + EN +K+ E K++L ++E+ + +E ++ + ++NEEN
Sbjct: 1257 TVDDDDDDNDPENRIAKKM-LLEEIKANLSSDEDGSSDDEPEEGKK-----RTGKQNEEN 1310
Query: 268 KDEE--KSQQENEENKDEEKSQQ--------ENELKKNEGGEKETGEITEEKSKQENEET 317
+E K+Q +E + D E+S++ ++L ++G E+GE + K K+ E
Sbjct: 1311 PGDEEAKNQVNSESDSDSEESKKPRYRHRLLRHKLTVSDG---ESGEEKKTKPKEHKEVK 1367
Query: 318 SETNSK--DKENEESNQNGSDAKEQVGENHEQD------SKQGTEETNGTEGGEKEEHDK 369
K +++E+S+ S E+V E+ ++ +K+ E N +K++ +
Sbjct: 1368 GRNRRKVSSEDSEDSDFQESGVSEEVSESEDEQRPRTRSAKKAELEENQRSYKQKKKRRR 1427
Query: 370 IK--EDTSSDNQVQDGEKNNEAREENYSGDNASSAVVDNKSQESSNKTEEQFDKKEKNEF 427
IK ED+SS+N+ E+ E EE EE+ +++E
Sbjct: 1428 IKVQEDSSSENKSNSEEEEEEKEEE-----------------------EEEEEEEE---- 1460
Query: 428 ELESQKNSNETTESTDSTITQNSQGNESEKDQAQTENDTPKGSASESDEQK----QEQEQ 483
E +++ N+ ++S + + + +K + +T+N + E +E++ + + +
Sbjct: 1461 --EEEEDENDDSKSPGKGRKKIRKILKDDKLRTETQN-----ALKEEEERRKRIAERERE 1513
Query: 484 NNTTKDDVQTTDTSSQNGNDTT----EKQNETSE 513
++ ++ D S TT ++ ET E
Sbjct: 1514 REKLREVIEIEDASPTKCPITTKLVLDEDEETKE 1547
Score = 36.6 bits (83), Expect = 0.26
Identities = 39/165 (23%), Positives = 63/165 (37%), Gaps = 21/165 (12%)
Query: 148 AENKENESVEKENEEIKKEVEDTETGESIEEKSHLEN--------------EESKETGEI 193
+E+K N V+K ++ + E++E S + +N E SKE G
Sbjct: 7 SESKLNTLVQKLHDFLAHSSEESEETSSPPRLAMNQNTDKISGSGSNSDMMENSKEEGTS 66
Query: 194 SEEKSHLENEESKETGESSEEKSHLENEESKETGESSEEKSHLENEENKDEEKSKQENEE 253
S EKS + S K ++E E+ E + EN EN +S +
Sbjct: 67 SSEKSKSSGSSRSKRKPSIVTKYVESDDEKPLDDETVNEDASNENSENDITMQSLPKGTV 126
Query: 254 IKDGEKIQQENEENKDEEKSQQENEENKDEEKSQQENELKKNEGG 298
I E + +E+K + E + K + EN K+ E G
Sbjct: 127 IVQPEPV-------LNEDKDDFKGPEFRSRSKMKTENLKKRGEDG 164
Score = 34.3 bits (77), Expect = 1.3
Identities = 31/134 (23%), Positives = 51/134 (37%), Gaps = 21/134 (15%)
Query: 539 AGDQADSTTTTSSSETQDGNTNHGEYKDTTNENPEKNSGQEGTQESGSSSNTFDNKDAAS 598
A ++S T + D + E + T+ P Q + SGS SN+
Sbjct: 3 AEPMSESKLNTLVQKLHDFLAHSSEESEETSSPPRLAMNQNTDKISGSGSNS-------- 54
Query: 599 NKVQLTTTSDTSSEQKKDESSSAESKSESSQNDNANSGQSNTTSDESANDNKDSSQVTTS 658
E K+E +S+ KS+SS + + S T ++D K T +
Sbjct: 55 ----------DMMENSKEEGTSSSEKSKSSGSSRSKRKPSIVTKYVESDDEKPLDDETVN 104
Query: 659 SENSAEGNSNTENN 672
+ S N N+EN+
Sbjct: 105 EDAS---NENSEND 115
Score = 32.0 bits (71), Expect = 6.5
Identities = 19/91 (20%), Positives = 43/91 (46%), Gaps = 3/91 (3%)
Query: 658 SSENSAEGNSNTENNSDENQNDSKNNENTNDSGNTSNDANVNENQNENAAQTKTSENEGD 717
SSE S E +S ++N + + + +D S + + ++ ++ + S+ +
Sbjct: 25 SSEESEETSSPPRLAMNQNTDKISGSGSNSDMMENSKEEGTSSSEKSKSSGSSRSKRKPS 84
Query: 718 AQNESVESKKE---NNESAHKDVDNNSNSND 745
+ VES E ++E+ ++D N ++ ND
Sbjct: 85 IVTKYVESDDEKPLDDETVNEDASNENSEND 115
>DMP1_HUMAN (Q13316) Dentin matrix acidic phosphoprotein 1 precursor
(Dentin matrix protein-1) (DMP-1)
Length = 513
Score = 128 bits (322), Expect = 5e-29
Identities = 123/537 (22%), Positives = 227/537 (41%), Gaps = 64/537 (11%)
Query: 222 ESKETGESSEEKSHLENEENKDEEKSKQENEEIKDGEKIQQENEENKDEEKSQQENEENK 281
++ E+ +S E K HL E S E +G K+ E + N+D S Q +EE
Sbjct: 23 QNNESEDSEEWKGHLAQAPTPPLESS-----ESSEGSKVSSEEQANEDPSDSTQ-SEEGL 76
Query: 282 DEEKSQQENELKKNEGGEKETGEITEEKSKQENEETSETNSKDKENEESNQNGSDAKEQV 341
+ Q L G + TG+ ++K E++ +T D ++
Sbjct: 77 GSDDHQYIYRLAG--GFSRSTGKGGDDKDDDEDDSGDDTFGDDDSGPGPKDRQEGGNSRL 134
Query: 342 GENHEQDSKQGTEETNGTEGGEK-----EEHDKIKEDTSSDNQVQDGEKNNEAREENY-- 394
G + + D E + +G + E ++ + D++ + G+ E+ E +
Sbjct: 135 GSDEDSDDTIQASEESAPQGQDSAQDTTSESRELDNEDRVDSKPEGGDSTQESESEEHWV 194
Query: 395 -SGDNASSAVVDNKS--QESSNKTEEQFDKKEKNEFELESQ-KNSNETTESTDSTITQNS 450
G + S+ D E + + + E+ + S S E+ E+++ TQ+S
Sbjct: 195 GGGSDGESSHGDGSELDDEGMQSDDPESIRSERGNSRMNSAGMKSKESGENSEQANTQDS 254
Query: 451 QGNESEKDQAQTENDTPKGSASESDEQKQEQEQNNTTKDDVQTTDTSSQNGNDTTEKQNE 510
G S+ + + K SE D++ + + N T ++V++ T + N DT
Sbjct: 255 GG--SQLLEHPSRKIFRKSRISEEDDRSELDDNN--TMEEVKSDSTENSNSRDTG----- 305
Query: 511 TSEDANSKKEDSSALNTTPNNEDSKSGVAGDQADSTTTTSSSETQDGNTNHGEYKDTTNE 570
S+ K DS EDSK ++ +++ + SS +Q+ N + E
Sbjct: 306 LSQPRRDSKGDSQ--------EDSKENLSQEESQNVDGPSSESSQEANLSSQE------- 350
Query: 571 NPEKNSGQEGTQESGSSSNTFDNKDAASNKVQLTTTSDTSSEQKKDESSSAESKSESSQN 630
NS + +QE S + DN D ++ V+ SD+S E S ++S+S Q
Sbjct: 351 ----NSSE--SQEEVVSESRGDNPDPTTSYVEDQEDSDSSEEDSSHTLSHSKSESREEQA 404
Query: 631 DNANSGQSNTT--SDESANDNKDSSQVTTSSENSAEGNSNTENNSDENQNDSKNNENTND 688
D+ +S N + S ES D SSQ S +S+ + + E++S+E+ +DS+ D
Sbjct: 405 DSESSESLNFSEESPESPEDENSSSQEGLQSHSSSAESQSEESHSEEDDSDSQ------D 458
Query: 689 SGNTSNDANVNENQNENAAQTKTSENEGDAQNESVESKKENNESAHKDVDNNSNSND 745
S + D+N E+++ +SE +G +N +ES+K ++ H + + ND
Sbjct: 459 SSRSKEDSNSTESKS-------SSEEDGQLKNIEIESRKLTVDAYHNKPIGDQDDND 508
Score = 112 bits (280), Expect = 4e-24
Identities = 123/538 (22%), Positives = 228/538 (41%), Gaps = 74/538 (13%)
Query: 168 EDTETGESIEEKSHL--------ENEESKETGEIS-EEKSHLENEESKETGESSEEKSH- 217
++ E+ +S E K HL E+ ES E ++S EE+++ + +S ++ E H
Sbjct: 23 QNNESEDSEEWKGHLAQAPTPPLESSESSEGSKVSSEEQANEDPSDSTQSEEGLGSDDHQ 82
Query: 218 ----LENEESKETGESSEEKSHLENEENKDEEKSKQENEEIKDGEKIQQENEENKDEEKS 273
L S+ TG+ ++K E++ D +++ G K +QE ++
Sbjct: 83 YIYRLAGGFSRSTGKGGDDKDDDEDDSGDDTFG----DDDSGPGPKDRQEGGNSRLGSDE 138
Query: 274 QQENEENKDEEKSQQENELKKNEGGEKETGEITEEKSKQENEETSETNSKDKENEESNQN 333
++ EE + Q G+ + T E + +NE+ ++ E +S Q
Sbjct: 139 DSDDTIQASEESAPQ---------GQDSAQDTTSESRELDNEDRVDSKP---EGGDSTQE 186
Query: 334 GSDAKEQVGENHEQDSKQGTEETNGTEGGEKEEHDKIKEDTSSDNQVQDGEKNNEAREEN 393
+ VG + +S G EG + ++ + I+ + + G K+ E
Sbjct: 187 SESEEHWVGGGSDGESSHGDGSELDDEGMQSDDPESIRSERGNSRMNSAGMKSKE----- 241
Query: 394 YSGDNASSAVVDNK--SQESSNKTEEQFDKKEKNEFELESQKNSNETTESTDSTITQNSQ 451
SG+N+ A + SQ + + + F K +E + S+ + N T E S T+NS
Sbjct: 242 -SGENSEQANTQDSGGSQLLEHPSRKIFRKSRISEEDDRSELDDNNTMEEVKSDSTENSN 300
Query: 452 GNESEKDQAQTENDTPKGSASESDEQKQEQEQNNTTKDDVQTTDTSSQNGNDTTEKQNET 511
++ Q + ++ KG + E ++ QE++ Q D S +E+
Sbjct: 301 SRDTGLSQPRRDS---KGDSQEDSKENLSQEES-------QNVDGPS----------SES 340
Query: 512 SEDANSKKEDSSALNTTPNNEDSKSGVAGDQADSTTTTSSSETQDGNTNHGEYKDTTNEN 571
S++AN SS N++ + E+ S GD D TTS E Q+ + + E T +
Sbjct: 341 SQEANL----SSQENSSESQEEVVSESRGDNPD--PTTSYVEDQEDSDSSEEDSSHTLSH 394
Query: 572 PEKNSGQEGTQESGSSSNTFDNKDAASNKVQLTTTSDTSSEQKKDESSSAESKSESSQND 631
+ S +E S S F + S + + + +S E + SSSAES+SE S
Sbjct: 395 SKSESREEQADSESSESLNFSEESPESPEDE----NSSSQEGLQSHSSSAESQSEES--- 447
Query: 632 NANSGQSNTTSDESANDNKDSSQVTTSSENSAEGN-SNTENNSDENQNDSKNNENTND 688
+S + ++ S +S+ +DS+ + S + +G N E S + D+ +N+ D
Sbjct: 448 --HSEEDDSDSQDSSRSKEDSNSTESKSSSEEDGQLKNIEIESRKLTVDAYHNKPIGD 503
Score = 110 bits (276), Expect = 1e-23
Identities = 104/489 (21%), Positives = 212/489 (43%), Gaps = 37/489 (7%)
Query: 288 QENELKKNEGGEKETGEITEEKSKQENEETSETNSKDKENEESNQNGSDA---KEQVGEN 344
Q NE +E E+ G + + + S SK E++N++ SD+ +E +G +
Sbjct: 23 QNNE---SEDSEEWKGHLAQAPTPPLESSESSEGSKVSSEEQANEDPSDSTQSEEGLGSD 79
Query: 345 HEQDSKQ---GTEETNGTEGGEKEE-HDKIKEDTSSDNQVQDGEKNNEAREENYSGDNAS 400
Q + G + G G +K++ D +DT D+ G K+ + + G +
Sbjct: 80 DHQYIYRLAGGFSRSTGKGGDDKDDDEDDSGDDTFGDDDSGPGPKDRQEGGNSRLGSDED 139
Query: 401 SAVVDNKSQESSNKTEEQFDKKEKNEFELESQKNSNETTESTDSTITQNSQGNESEKDQA 460
S S+ES+ + ++ EL+++ + E DST Q +ESE+
Sbjct: 140 SDDTIQASEESAPQGQDSAQDTTSESRELDNEDRVDSKPEGGDST-----QESESEEHWV 194
Query: 461 Q--TENDTPKGSASESDEQKQEQEQNNTTKDDVQTTDTSSQNGNDTTEKQNETSEDANSK 518
++ ++ G SE D++ + + + + + + +S +++ E SE AN++
Sbjct: 195 GGGSDGESSHGDGSELDDEGMQSDDPESIRSERGNSRMNSAGMK--SKESGENSEQANTQ 252
Query: 519 KEDSSALNTTPNNEDSKSGVAGDQADSTTTTSSSETQDGNTNHGEYKDTTNENPEKNSGQ 578
S L P+ + + ++ D SE D NT D+T + +++G
Sbjct: 253 DSGGSQLLEHPSRKIFRKSRISEEDDR------SELDDNNTMEEVKSDSTENSNSRDTGL 306
Query: 579 EGTQESGSSSNTFDNKDAASNKVQLTTTSDTSSEQKKDESSSAESKSESSQNDNANSGQS 638
+ + D+K+ S + +S ++ SS E+ SES + + S
Sbjct: 307 SQPRRDSKGDSQEDSKENLSQEESQNVDGPSSESSQEANLSSQENSSESQEEVVSESRGD 366
Query: 639 N---TTSDESANDNKDSSQVTTSSENSAEGNSNTENNSDENQNDSKNNENTNDSGNTSND 695
N TTS ++ DSS+ E+S+ S++++ S E Q DS+++E+ N S +
Sbjct: 367 NPDPTTSYVEDQEDSDSSE-----EDSSHTLSHSKSESREEQADSESSESLNFSEESPES 421
Query: 696 ANVNENQNENAAQTKTSENEGDAQNESVESKKENNESAHKDVDNNSNSNDQGSSDTSVTQ 755
+ ++ Q+ +S A+++S ES E ++S +D + ++ S +S +
Sbjct: 422 PEDENSSSQEGLQSHSS----SAESQSEESHSEEDDSDSQDSSRSKEDSNSTESKSSSEE 477
Query: 756 DDKESRVDL 764
D + +++
Sbjct: 478 DGQLKNIEI 486
Score = 105 bits (261), Expect = 6e-22
Identities = 107/533 (20%), Positives = 240/533 (44%), Gaps = 72/533 (13%)
Query: 79 RHKEDEEEADELDNKHDEQTKLDDVNGVEDNSEHKEDSVEQESEESSQNAKTD--LEGEQ 136
R++ +E E E H Q + E + K S EQ +E+ S + +++ L +
Sbjct: 21 RYQNNESEDSEEWKGHLAQAPTPPLESSESSEGSKVSSEEQANEDPSDSTQSEEGLGSDD 80
Query: 137 HT------------------EKVDEENDNAENKENESVEKENEEIKKEVEDTETGESIEE 178
H +K D+E+D+ ++ + + ++E ++ G
Sbjct: 81 HQYIYRLAGGFSRSTGKGGDDKDDDEDDSGDDTFGDDDSGPGPKDRQEGGNSRLGS---- 136
Query: 179 KSHLENEESKETGEISEEKSHLENEESKETGESSEEKSHLENEESKETGESSEEKSHLEN 238
+E+S +T + SEE + + +++T S E + + +SK G S ++S E+
Sbjct: 137 -----DEDSDDTIQASEESAPQGQDSAQDTTSESRELDNEDRVDSKPEGGDSTQES--ES 189
Query: 239 EENKDEEKSKQENEEIKDGEKIQQENEENKDEEKSQQENEENKDEEKSQQENELKKNEGG 298
EE+ S E+ DG ++ E ++ D E + E ++ +
Sbjct: 190 EEHWVGGGSDGESSH-GDGSELDDEGMQSDDPESIRSERGNSRMNSAGMKS--------- 239
Query: 299 EKETGEITEEKSKQEN--EETSETNSKDKENEESNQNGSDAKEQVGENH--EQDSKQGTE 354
KE+GE +E+ + Q++ + E S+ K +S + D + ++ +N+ E+ TE
Sbjct: 240 -KESGENSEQANTQDSGGSQLLEHPSR-KIFRKSRISEEDDRSELDDNNTMEEVKSDSTE 297
Query: 355 ETNGTEGGEKEEHDKIKEDTSSDNQVQDGEKNNEAREENYSGDNASSAVVDN-KSQESSN 413
+N + G + + D+ D+Q E ++ +N G ++ S+ N SQE+S+
Sbjct: 298 NSNSRDTGLSQP----RRDSKGDSQEDSKENLSQEESQNVDGPSSESSQEANLSSQENSS 353
Query: 414 KTEEQF------DKKEKNEFELESQKNSNETTESTDSTITQNSQGNESEKDQAQTENDTP 467
+++E+ D + +E Q++S+ + E + T++ + +ES ++QA +E+
Sbjct: 354 ESQEEVVSESRGDNPDPTTSYVEDQEDSDSSEEDSSHTLSHSK--SESREEQADSESSES 411
Query: 468 KGSASESDEQKQEQEQNNTTKDDVQTTDTSSQNGNDTTEKQNETSEDANSKKEDSSALNT 527
+ ES E +++ N+++++ +Q+ +S+++ SE+++S+++DS + ++
Sbjct: 412 LNFSEESPESPEDE--NSSSQEGLQSHSSSAES----------QSEESHSEEDDSDSQDS 459
Query: 528 TPNNEDSKSGVAGDQADSTTTTSSSETQDGNTNHGEYKDTTNENPEKNSGQEG 580
+ + EDS S + ++ + E + Y + + + N Q+G
Sbjct: 460 SRSKEDSNSTESKSSSEEDGQLKNIEIESRKLTVDAYHNKPIGDQDDNDCQDG 512
Score = 95.5 bits (236), Expect = 5e-19
Identities = 93/477 (19%), Positives = 197/477 (40%), Gaps = 69/477 (14%)
Query: 331 NQNGSDAKEQVGENHEQDSKQGTEETNGTEGGEKEEHDKIKEDTSSDNQVQDGEKNNEAR 390
N D++E G + Q E + +EG + ++ ED S Q ++G +++ +
Sbjct: 24 NNESEDSEEWKG-HLAQAPTPPLESSESSEGSKVSSEEQANEDPSDSTQSEEGLGSDDHQ 82
Query: 391 EENYSGDNASSAVV---DNKSQESSNKTEEQFDKKEKNEFELESQKNSNETTESTDSTIT 447
S + D+K + + ++ F + + Q+ N S +
Sbjct: 83 YIYRLAGGFSRSTGKGGDDKDDDEDDSGDDTFGDDDSGPGPKDRQEGGNSRLGSDE---- 138
Query: 448 QNSQGNESEKDQAQTENDTPKGSASESDEQKQEQEQNNTTKDDVQTTDTSSQNGNDTTEK 507
+S+ +E P+G S D + +E +N + D+ + G+ T E
Sbjct: 139 ------DSDDTIQASEESAPQGQDSAQDTTSESRELDNEDR-----VDSKPEGGDSTQES 187
Query: 508 QNET-----SEDANSKKEDSSALNTTPNNEDSKSGVAGDQADSTTTTSSSETQDGNTNHG 562
++E D S D S L+ D + ++ +S ++ ++++
Sbjct: 188 ESEEHWVGGGSDGESSHGDGSELDDEGMQSDDPESIRSERGNSRMNSAGMKSKESG---- 243
Query: 563 EYKDTTNENPEKNSGQEGTQESGSSSNTFDNKDAASNKVQLTTTSDTSSEQKKDESSSAE 622
+NS Q TQ+SG S K +++ D S + D ++ E
Sbjct: 244 -----------ENSEQANTQDSGGSQLLEHPSRKIFRKSRISEEDDRS--ELDDNNTMEE 290
Query: 623 SKSESSQNDNA-NSGQSNTTSDESANDNKDSSQVTT----------SSENSAEGNSNTEN 671
KS+S++N N+ ++G S D + +DS + + SSE+S E N +++
Sbjct: 291 VKSDSTENSNSRDTGLSQPRRDSKGDSQEDSKENLSQEESQNVDGPSSESSQEANLSSQE 350
Query: 672 NSDENQND---SKNNENTNDSGNTSNDANVNENQNENAAQT------KTSENEGDAQN-- 720
NS E+Q + +N + + + D +++ E+++ T ++ E + D+++
Sbjct: 351 NSSESQEEVVSESRGDNPDPTTSYVEDQEDSDSSEEDSSHTLSHSKSESREEQADSESSE 410
Query: 721 ------ESVESKKENNESAHKDVDNNSNSNDQGSSDTSVTQDDKESRVDLGTLPESN 771
ES ES ++ N S+ + + ++S+S + S ++ +DD +S+ + +SN
Sbjct: 411 SLNFSEESPESPEDENSSSQEGLQSHSSSAESQSEESHSEEDDSDSQDSSRSKEDSN 467
Score = 90.5 bits (223), Expect = 2e-17
Identities = 91/423 (21%), Positives = 173/423 (40%), Gaps = 39/423 (9%)
Query: 385 KNNEARE-ENYSGDNASSAVVDNKSQESSN----KTEEQFDKKEKNEFELESQKNSNETT 439
+NNE+ + E + G A + +S ESS +EEQ ++ + + E S++
Sbjct: 23 QNNESEDSEEWKGHLAQAPTPPLESSESSEGSKVSSEEQANEDPSDSTQSEEGLGSDDHQ 82
Query: 440 ---ESTDSTITQNSQGNESEKDQAQTENDTPKGSASESDEQKQEQEQNNTTKDDVQTTDT 496
+G + + D D G K QE N+
Sbjct: 83 YIYRLAGGFSRSTGKGGDDKDDDEDDSGDDTFGDDDSGPGPKDRQEGGNSRLG------- 135
Query: 497 SSQNGNDTTEKQNETSEDANSKKEDSSALNTTPNNEDSKSGVAGDQADSTTTTSSSET-- 554
S ++ +DT + E++ +D+++ + +NED + DST + S E
Sbjct: 136 SDEDSDDTIQASEESAPQGQDSAQDTTSESRELDNEDRVDSKP-EGGDSTQESESEEHWV 194
Query: 555 ---QDGNTNHGEYKDTTNENPEKNSGQEGTQESGSS---SNTFDNKDAASNKVQLTTTSD 608
DG ++HG+ + +E + + + E G+S S +K++ N Q T
Sbjct: 195 GGGSDGESSHGDGSELDDEGMQSDDPESIRSERGNSRMNSAGMKSKESGENSEQANTQDS 254
Query: 609 TSSEQKKDESSSAESKSESSQNDNANSGQSNTTSDESANDNKDSS--------QVTTSSE 660
S+ + S KS S+ D+ + N T +E +D+ ++S Q S+
Sbjct: 255 GGSQLLEHPSRKIFRKSRISEEDDRSELDDNNTMEEVKSDSTENSNSRDTGLSQPRRDSK 314
Query: 661 NSAEGNSNTENNSDENQNDSKNNENTNDSGNTSNDANVNENQNENAAQTKTSENEGDAQN 720
++ +S + +E+QN + ++ N S+ N +E+Q E SE+ GD
Sbjct: 315 GDSQEDSKENLSQEESQNVDGPSSESSQEANLSSQENSSESQEE-----VVSESRGD-NP 368
Query: 721 ESVESKKENNESAHKDVDNNSNSNDQGSSDTSVTQDDKESRVDLGTLPESNGESHHNDVS 780
+ S E+ E + +++S++ S++ Q D ES L E + ES ++ S
Sbjct: 369 DPTTSYVEDQEDSDSSEEDSSHTLSHSKSESREEQADSESSESL-NFSEESPESPEDENS 427
Query: 781 SAE 783
S++
Sbjct: 428 SSQ 430
Score = 86.3 bits (212), Expect = 3e-16
Identities = 87/396 (21%), Positives = 161/396 (39%), Gaps = 59/396 (14%)
Query: 62 GRKDLKPRVEETSVIDARHKEDEEEADELDNKHDEQTKLDDVNGVEDNSEHKEDSVEQES 121
G L + I A + + D + E +LD+ + V+ E + + E ES
Sbjct: 130 GNSRLGSDEDSDDTIQASEESAPQGQDSAQDTTSESRELDNEDRVDSKPEGGDSTQESES 189
Query: 122 EESSQNAKTDLEGEQHT-EKVDEENDNAENKENESVEKENEEIKKE-VEDTETGESIEEK 179
EE +D E ++D+E +++ E+ E+ N + ++ E+GE+ E+
Sbjct: 190 EEHWVGGGSDGESSHGDGSELDDEGMQSDDPESIRSERGNSRMNSAGMKSKESGENSEQA 249
Query: 180 SHLENEESK----------ETGEISEEKSHLENEESKETGESSEEKSHLENEESKETGES 229
+ ++ S+ ISEE E +++ E + + EN S++TG S
Sbjct: 250 NTQDSGGSQLLEHPSRKIFRKSRISEEDDRSELDDNNTMEEVKSDST--ENSNSRDTGLS 307
Query: 230 -----SEEKSHLENEENKDEEKSKQ----ENEEIKDGEKIQQENEENKDEEKSQQENEEN 280
S+ S +++EN +E+S+ +E ++ QEN EE + +N
Sbjct: 308 QPRRDSKGDSQEDSKENLSQEESQNVDGPSSESSQEANLSSQENSSESQEEVVSESRGDN 367
Query: 281 KDEEKSQQENELKKNEGGEKETGEITEEKSKQENEETSETNSKDKENEESNQNGSDAKEQ 340
D S E+ +E S E++S T S K Q S++ E
Sbjct: 368 PDPTTSYVED----------------QEDSDSSEEDSSHTLSHSKSESREEQADSESSES 411
Query: 341 VGENHEQDSKQGTEETNGTEGGEKEEHDKIKEDTSSDNQVQDGEKNNEAREENYSGDNAS 400
+ N ++S + E+ N + + H E S EE++S ++ S
Sbjct: 412 L--NFSEESPESPEDENSSSQEGLQSHSSSAESQS---------------EESHSEEDDS 454
Query: 401 SAVVDNKSQESSNKTEEQFDKKEKNE---FELESQK 433
+ ++S+E SN TE + +E + E+ES+K
Sbjct: 455 DSQDSSRSKEDSNSTESKSSSEEDGQLKNIEIESRK 490
Score = 74.3 bits (181), Expect = 1e-12
Identities = 61/240 (25%), Positives = 106/240 (43%), Gaps = 23/240 (9%)
Query: 60 KLGRKDLKPRVEETSVIDARHKEDEEEADELDNKHDEQTKLDDVNGVEDNSEHKEDSVEQ 119
K+ RK ++ S +D + +E ++D +N + T L + + +EDS E
Sbjct: 266 KIFRKSRISEEDDRSELDDNNTMEEVKSDSTENSNSRDTGLSQPRR-DSKGDSQEDSKEN 324
Query: 120 ESEESSQNAK-TDLEGEQHTEKVDEENDNAENKE--NESVEKENEEIKKEVEDTETGESI 176
S+E SQN E Q +EN + +E +ES + VED E +S
Sbjct: 325 LSQEESQNVDGPSSESSQEANLSSQENSSESQEEVVSESRGDNPDPTTSYVEDQEDSDSS 384
Query: 177 EEKSHLENEESKETGEISEEKSHLENEESKETGESSEEKSHLENEESKETGESSEEKSHL 236
EE S SK E EE++ E+ ES E S E EN S+E +S H
Sbjct: 385 EEDSSHTLSHSKS--ESREEQADSESSESLNFSEESPESPEDENSSSQEGLQS-----HS 437
Query: 237 ENEENKDEEKSKQENEEIKDGEKIQQENEENKDEEKSQQENEENKDEEKSQQENELKKNE 296
+ E++ EE +E ++ +++D +S++++ + + S+++ +LK E
Sbjct: 438 SSAESQSEESHSEE------------DDSDSQDSSRSKEDSNSTESKSSSEEDGQLKNIE 485
Score = 57.0 bits (136), Expect = 2e-07
Identities = 49/216 (22%), Positives = 97/216 (44%), Gaps = 34/216 (15%)
Query: 63 RKDLKPRVEETSVIDARHKEDEEEADELDNKHDEQTKLDDVNGVEDNSEHKEDSVEQESE 122
R+D K +E D++ +EE+ +D E ++ +++ E++SE +E+ V +
Sbjct: 310 RRDSKGDSQE----DSKENLSQEESQNVDGPSSESSQEANLSSQENSSESQEEVVSESRG 365
Query: 123 ESSQNAKTDLEGEQHTEKVDEENDNAENKENESVEKENEEIKKEVEDTETGESIE----- 177
++ + +E + E++D++E + ++ E ++E D+E+ ES+
Sbjct: 366 DNPDPTTSYVEDQ-------EDSDSSEEDSSHTLSHSKSESREEQADSESSESLNFSEES 418
Query: 178 -EKSHLENEESKE-------TGEISEEKSHLENEES--------KETGESSEEKSHLENE 221
E EN S+E + E E+SH E ++S KE S+E KS E +
Sbjct: 419 PESPEDENSSSQEGLQSHSSSAESQSEESHSEEDDSDSQDSSRSKEDSNSTESKSSSEED 478
Query: 222 ESKETGESSEEKSHLENEENKDEEKSKQENEEIKDG 257
+ E K ++ NK Q++ + +DG
Sbjct: 479 GQLKNIEIESRKLTVDAYHNK--PIGDQDDNDCQDG 512
Score = 32.0 bits (71), Expect = 6.5
Identities = 24/122 (19%), Positives = 47/122 (37%), Gaps = 14/122 (11%)
Query: 36 YQIGHSREQKASYGASTKTGNEVVKLGRKDLKPRVEETSVIDARHKEDEEEADELDNKHD 95
+ + HS+ + A +++ + P E +S + + + H
Sbjct: 390 HTLSHSKSESREEQADSESSESLNFSEESPESPEDENSSSQEGLQSHSSSAESQSEESHS 449
Query: 96 EQTKLDDVNGVEDNSEHKEDSVEQE----SEESSQNAKTDLEGEQ------HTEKVDEEN 145
E+ D +D+S KEDS E SEE Q ++E + H + + +++
Sbjct: 450 EEDDSDS----QDSSRSKEDSNSTESKSSSEEDGQLKNIEIESRKLTVDAYHNKPIGDQD 505
Query: 146 DN 147
DN
Sbjct: 506 DN 507
>YFI6_YEAST (P43597) Hypothetical 137.7 kDa protein in UGS1-FAB1
intergenic region
Length = 1233
Score = 128 bits (321), Expect = 7e-29
Identities = 182/797 (22%), Positives = 326/797 (40%), Gaps = 91/797 (11%)
Query: 56 NEVVKLGRKDLKPRVEETSVIDARHKEDEEEAD-ELDNKH--DEQTKLDDVNGVEDNSEH 112
NE +K+ +P E I R++ ++ D ++ NK DE + + N E+ +EH
Sbjct: 234 NEDIKVNIVQDEPVNVEKMDIRTRNESSDKTFDIDVPNKDNVDETSSKSENNINEEKAEH 293
Query: 113 ----KEDSVEQESEESSQNAKTDLEGEQHTEKVDEENDNAENK--ENESVEKENEEIKK- 165
+E+ + +E ++ + K LE H + +EN A K E+ES+ K K+
Sbjct: 294 TLPREENEILNVNEGNAASFKHQLE--PHGLEAGDENGQASTKDVESESLTKNGFNFKEN 351
Query: 166 EVEDTETGESIEEKSHLEN-------EESKETGEISEEKSHLENEESKETGESSEEKS-- 216
E + + GE + +S + + KET EI +E H+ ++ KE + +E S
Sbjct: 352 ESKHLKAGEKQQTESDRDGISPSVLAKNQKET-EIGKE-DHVFEQKDKEDEKCRKELSVN 409
Query: 217 HLENEESKETGESSEEKSHLENEENKDEEKSKQENEEIKDGEKIQQENEENKDEEKSQQE 276
H N S+ E E ++++ + I D EK Q + E ++E
Sbjct: 410 HENNMSHNFNAAGSDSIIPPETERETYDDETMGPTKRISDNEKNLQHGTNDISVEVEKEE 469
Query: 277 NEENKDEEKSQQENELKKNEGGEKE---TGEI--TEEKSKQENEETSETNSKDKENEESN 331
EE ++EE S K+N GE+E E+ TEE+S + EE + K E E +
Sbjct: 470 EEEEEEEENSTFSKVKKENVTGEQEAVRNNEVSGTEEESTSKGEEIMGGDEKQSEAGEKS 529
Query: 332 Q----NGSDAKEQVGENH---EQDSKQGTEETNGTE-GGEKEEHDKIKEDTSSDNQVQDG 383
GS ++ +++ E +++ T+E TE GE + D ++D V+
Sbjct: 530 SIIEIEGSANSAKISKDNLVLEDEAEAPTQENKPTEVVGEIDIPDAPRDDVEIVEAVEKN 589
Query: 384 --EKNNEAREENYSG-----DNASSAVVDNK-SQESSNKTEEQFDKKEKNEFELESQKNS 435
++ E +E+ G D A+ D+K + + E KK++ EL ++K
Sbjct: 590 IIPEDLEVAKEDQEGEQVKLDEPVKAMKDDKIAMRGAESISEDMKKKQEGTAELSNEKAK 649
Query: 436 NETTESTDSTITQNSQGNESEKDQAQTENDTPKGSASESDEQKQEQEQN-NTTKDDVQTT 494
E D T ++++G E EK + K S E Q E++ K+DV+
Sbjct: 650 KE----VDETARESAEGVEVEKSKTPESPKVVKRCTSGRPEDLQINERDPEVLKEDVRVP 705
Query: 495 DTSSQNGNDTTEKQNETSEDANSKKEDSSALNTTPNNEDSKSGVAGDQADSTTTTSSSE- 553
D + TT + NS++ED + + E +++ D D +TTS E
Sbjct: 706 DEDVKPEIATTIE--------NSEEEDPKSQRVQISTEQAET-TQKDMGDVGSTTSFKEE 756
Query: 554 --------TQDG--------NTNHGEYKDTTNENPEKNSGQEGTQESGSSSNTFDNKDAA 597
TQ+G N HGE + +EN + GT E ++ K
Sbjct: 757 EKPKRFEITQEGDKITGKDTNHEHGEATEAASEN--SKASDVGTAEKYIEPSSESVKKDT 814
Query: 598 SNKVQLTTTSDTSSEQKKDESSSAESKSESSQNDNANSGQSNTTSDESANDNKDSSQVTT 657
++ + T + K E + ++ E+ N + D + ++S+ T
Sbjct: 815 EEDAEVENSEKTEFIKVKAELENLDAPKEAEVTAELNKENEDVEVDTEEDAEVENSEKTE 874
Query: 658 SSENSAE-GNSNTENNSDENQNDSKNNENTNDSGNTSNDANVN-----ENQNENAAQTKT 711
+ AE GN + ++ +K NE+ + + D E E+ T+
Sbjct: 875 FIKVKAELGNLDAPKEAEVTAELNKENEDVEVAATSKEDIETKCSEPAETPIEDGTCTEA 934
Query: 712 SENEGDAQNESVESKKENNESAHKDVDNNSNSNDQGSSDTSVTQDDKESRVDLGTL---- 767
++ DA E+V + EN E++ + DQ D +++ D+ + V+L L
Sbjct: 935 EVSKKDA--EAVTKEDENMENSKIAEALKDVTGDQEIDDINIS-DEFQRTVELPELEKQD 991
Query: 768 -PESNGESHHNDVSSAE 783
++ GE +V E
Sbjct: 992 IKDNKGEDKELEVEETE 1008
Score = 112 bits (281), Expect = 3e-24
Identities = 143/724 (19%), Positives = 289/724 (39%), Gaps = 79/724 (10%)
Query: 71 EETSVIDARHKEDEEEADELDNKHDEQTKLDDVNGVEDNSEHKEDSVEQES--EESSQNA 128
+E V + + KEDE+ EL H E+N H ++ +S ++
Sbjct: 387 KEDHVFEQKDKEDEKCRKELSVNH------------ENNMSHNFNAAGSDSIIPPETERE 434
Query: 129 KTDLEGEQHTEKVDEENDNAENKENE---SVEKENEEIKKEVEDTETGESIEEKSHLENE 185
D E T+++ + N ++ N+ VEKE EE ++E E+ T +++++ +
Sbjct: 435 TYDDETMGPTKRISDNEKNLQHGTNDISVEVEKEEEE-EEEEEENSTFSKVKKENVTGEQ 493
Query: 186 ESKETGEIS--EEKSHLENEE----SKETGESSEEKSHLENEESKETGESSEEKSHLENE 239
E+ E+S EE+S + EE ++ E+ E+ S +E E S + + S++ LE+E
Sbjct: 494 EAVRNNEVSGTEEESTSKGEEIMGGDEKQSEAGEKSSIIEIEGSANSAKISKDNLVLEDE 553
Query: 240 ENKDEEKSKQEN--------EEIKDGEKIQQENEENKDEE-----KSQQENEENKDEE-- 284
+++K + +D +I + E+N E K QE E+ K +E
Sbjct: 554 AEAPTQENKPTEVVGEIDIPDAPRDDVEIVEAVEKNIIPEDLEVAKEDQEGEQVKLDEPV 613
Query: 285 -------------KSQQENELKKNEGGEKETGEITEEKSKQENEETSETNSKDKENEESN 331
+S E+ KK EG T E++ EK+K+E +ET+ +++ E E+S
Sbjct: 614 KAMKDDKIAMRGAESISEDMKKKQEG----TAELSNEKAKKEVDETARESAEGVEVEKSK 669
Query: 332 QNGSDAKEQVGENHEQDSKQGTEETNGTEGGEKEEHDKIKEDTSSDNQVQDGEKNNEARE 391
S + + + Q E + + +KED ++ D +
Sbjct: 670 TPESPKVVKRCTSGRPEDLQINER----------DPEVLKEDVRVPDE--DVKPEIATTI 717
Query: 392 ENYSGDNASSAVVDNKSQESSNKTEEQFDKKEKNEFELESQKNSNETTESTDSTITQNSQ 451
EN ++ S V ++++ ++ D F+ E + E T+ D +++
Sbjct: 718 ENSEEEDPKSQRVQISTEQAETTQKDMGDVGSTTSFKEEEKPKRFEITQEGDKITGKDTN 777
Query: 452 GNESEKDQAQTENDTPKGSASESDEQKQEQEQNNTTKDDVQTTDTSSQNGNDTTEKQNET 511
E +A +EN K S + E+ E + KD + + + + + + E
Sbjct: 778 HEHGEATEAASENS--KASDVGTAEKYIEPSSESVKKDTEEDAEVENSEKTEFIKVKAEL 835
Query: 512 SEDANSKKEDSSALNTTPNNEDSKSGVAGD---QADSTTTTSSSETQDGNTNHGEYKDTT 568
E+ ++ KE NED + D + T + + GN + + + T
Sbjct: 836 -ENLDAPKEAEVTAELNKENEDVEVDTEEDAEVENSEKTEFIKVKAELGNLDAPKEAEVT 894
Query: 569 NENPEKNSGQEGTQESGSSSNTFDNKDAASNKVQLTTTSDTSSEQKKDESSSAESKSESS 628
E ++N E + + +S + K + + + + T +E K ++ + + E+
Sbjct: 895 AELNKEN---EDVEVAATSKEDIETKCSEPAETPIEDGTCTEAEVSKKDAEAVTKEDENM 951
Query: 629 QNDNANSGQSNTTSDESANDNKDSSQVTTSSE-NSAEGNSNTENNSDENQNDSKNNENTN 687
+N + T D+ +D S + + E E +N ++ + + + E
Sbjct: 952 ENSKIAEALKDVTGDQEIDDINISDEFQRTVELPELEKQDIKDNKGEDKELEVEETEKET 1011
Query: 688 DSGNTSNDANVNENQNENAAQTKTSENEGDAQNESVESKKENN-ESAHKDVDNNSNSNDQ 746
+ + N+ E +NE + + + ES+ + NN E+ +D N
Sbjct: 1012 SLPDLVVEENITEEKNEIKQEEEEVSQLDFNETESISKEAPNNDENGFEDQSTRENPKKA 1071
Query: 747 GSSD 750
+ D
Sbjct: 1072 SADD 1075
Score = 112 bits (280), Expect = 4e-24
Identities = 151/733 (20%), Positives = 294/733 (39%), Gaps = 133/733 (18%)
Query: 44 QKASYGASTKTGNEVVKLGRKDLKPRVEETSVIDARHKEDEEEADE--------LDNKHD 95
++ +Y T + + K+L+ + SV + +E+EEE +E +N
Sbjct: 432 ERETYDDETMGPTKRISDNEKNLQHGTNDISVEVEKEEEEEEEEEENSTFSKVKKENVTG 491
Query: 96 EQTKL--DDVNGVEDNSEHKEDSV----EQESEESSQNAKTDLEGEQHTEKVDEEN---- 145
EQ + ++V+G E+ S K + + E++SE +++ ++EG ++ K+ ++N
Sbjct: 492 EQEAVRNNEVSGTEEESTSKGEEIMGGDEKQSEAGEKSSIIEIEGSANSAKISKDNLVLE 551
Query: 146 DNAE--NKENESVE-----------KENEEIKKEVE------DTETGESIEEKSHLENEE 186
D AE +EN+ E +++ EI + VE D E + +E ++ +E
Sbjct: 552 DEAEAPTQENKPTEVVGEIDIPDAPRDDVEIVEAVEKNIIPEDLEVAKEDQEGEQVKLDE 611
Query: 187 ------------------SKETGEISEEKSHLENEESK-ETGESSEEKSHLENEESKETG 227
S++ + E + L NE++K E E++ E + E +T
Sbjct: 612 PVKAMKDDKIAMRGAESISEDMKKKQEGTAELSNEKAKKEVDETARESAEGVEVEKSKTP 671
Query: 228 ESSEEKSHLENEENKDEEKSKQENEEIKDGEKIQQENEENKDEEKSQQENEENKDEEKSQ 287
ES + + +D + ++++ E +K E ++ +E+ K E + EN E +D + +
Sbjct: 672 ESPKVVKRCTSGRPEDLQINERDPEVLK--EDVRVPDEDVKPEIATTIENSEEEDPKSQR 729
Query: 288 QENELKKNEGGEKETG-----------------EITEEKSKQENEETSETNSKDKENEES 330
+ ++ E +K+ G EIT+E K ++T+ + + E
Sbjct: 730 VQISTEQAETTQKDMGDVGSTTSFKEEEKPKRFEITQEGDKITGKDTNHEHGEATEAASE 789
Query: 331 NQNGSDA--KEQVGENHEQDSKQGTEETNGTEGGEKEEHDKIKEDTSSDNQVQDGEKNNE 388
N SD E+ E + K+ TEE E EK E K+K + + + ++ E E
Sbjct: 790 NSKASDVGTAEKYIEPSSESVKKDTEEDAEVENSEKTEFIKVKAELENLDAPKEAEVTAE 849
Query: 389 AREENYSGDNASSAVVDNKSQESSNKTEEQFDKKEKNEFELESQKNSNETTE----STDS 444
+EN ++ ++ E+S KTE F K + L++ K + T E + D
Sbjct: 850 LNKEN---EDVEVDTEEDAEVENSEKTE--FIKVKAELGNLDAPKEAEVTAELNKENEDV 904
Query: 445 TITQNSQGNESEKDQAQTENDTPKGSASESDEQKQEQEQNNTTKDD-------------- 490
+ S+ + K E G+ +E++ K++ E TK+D
Sbjct: 905 EVAATSKEDIETKCSEPAETPIEDGTCTEAEVSKKDAEA--VTKEDENMENSKIAEALKD 962
Query: 491 -------------------VQTTDTSSQNGNDTTEKQNETSEDANSKKEDSSALNTTPNN 531
V+ + Q+ D + E + K+ L N
Sbjct: 963 VTGDQEIDDINISDEFQRTVELPELEKQDIKDNKGEDKELEVEETEKETSLPDLVVEENI 1022
Query: 532 EDSKSGVAGD-----QADSTTTTSSSETQDGNTNHGEYKDTTNENPEKNSGQEGTQESGS 586
+ K+ + + Q D T S S+ N +G +T ENP+K S + ++
Sbjct: 1023 TEEKNEIKQEEEEVSQLDFNETESISKEAPNNDENGFEDQSTRENPKKASADDIFKDILD 1082
Query: 587 SSNTFDNKDAASNKVQLTTTSDTSS-EQKKDESSSAESKSESSQNDNANSGQSNTTSDES 645
+N F ++++ S+ ++ Q D S +E S+ +N TTS+
Sbjct: 1083 ETNEF------LEQLKIVDDSELNALLQSLDAKDSTTQTTEQSKKNNDKPQDVITTSEIR 1136
Query: 646 ANDNKDSSQVTTS 658
+ K+ + TS
Sbjct: 1137 KLNEKEPVYIYTS 1149
>MDN1_YEAST (Q12019) Midasin (MIDAS-containing protein)
Length = 4910
Score = 126 bits (317), Expect = 2e-28
Identities = 125/578 (21%), Positives = 250/578 (42%), Gaps = 54/578 (9%)
Query: 77 DARHKEDEEEADELDNKHDEQTKLDDVNGVEDNSEHKEDSVEQESEESSQNAKTDLEGEQ 136
D ++DE E D ++ + D +L+D++ E+N + DS E+E +E + D E
Sbjct: 4096 DKDERDDENEDDAVEMEGDMAGELEDLSNGEENDDEDTDSEEEELDE-----EIDDLNED 4150
Query: 137 HTEKVDEE--NDNAENKENESVEKENEEIKKEVEDTETGESIEEKSHLENEESKETGEIS 194
+D++ +D A + E +N + K + ED + E+ E++ + ++
Sbjct: 4151 DPNAIDDKMWDDKASDNSKEKDTDQNLDGKNQEEDVQAAENDEQQRDNKEGGDEDPNAPE 4210
Query: 195 EEKSHLENEE-SKETGESSEEKSHLENEESKETGESSEEKSHLENEENKDEEKSKQENEE 253
+ +EN+E ++E + E++ +++EE ++ + E L+ E+ + + +E++E
Sbjct: 4211 DGDEEIENDENAEEENDVGEQEDEVKDEEGEDLEANVPEIETLDLPEDMNLDSEHEESDE 4270
Query: 254 ---IKDG--EKIQQENEENKDEEKSQQENEENKDEEKSQQENELKKNEGGEKETGEITEE 308
+ DG + + +E N+DEE Q+ E+ +E E + GE ET EE
Sbjct: 4271 DVDMSDGMPDDLNKEEVGNEDEEVKQESGIESDNENDEPGPEE----DAGETETALDEEE 4326
Query: 309 KSKQENEETSETNSKDKENEESNQNGSDAKE-----QVGENHEQDSKQGTEETNGTEGGE 363
++++ + T++ +D+EN Q SD +E + EN E+ +Q TE +G E E
Sbjct: 4327 GAEEDVDMTNDEGKEDEENGPEEQAMSDEEELKQDAAMEENKEKGGEQNTEGLDGVE--E 4384
Query: 364 KEEHDKIKEDTSSDNQVQDGEKNNEAREENYSGDNASSAVVDNKSQE-SSNKTEEQFDKK 422
K + + I ++ + +A + D S N +E + T+ + +
Sbjct: 4385 KADTEDIDQEAAVQQDSGSKGAGADATDTQEQDDVGGSGTTQNTYEEDQEDVTKNNEESR 4444
Query: 423 EKNEFELESQKNSNETTESTDSTITQNSQGNESEKDQAQTENDTP------KGSASESDE 476
E+ L+ +S + I + +Q N E + + N+ P +G+ +E+D
Sbjct: 4445 EEATAALKQLGDSMKEYHRRRQDI-KEAQTNGEEDENLEKNNERPDEFEHVEGANTETD- 4502
Query: 477 QKQEQEQNNTTKDDVQTTDTSSQNGNDTTEK---QNETSEDANSKKEDSSALNTTPNNED 533
Q + T+D +QT D +D E+ Q E EDA+ +K D + E+
Sbjct: 4503 ---TQALGSATQDQLQTIDEDMAIDDDREEQEVDQKELVEDADDEKMDI-------DEEE 4552
Query: 534 SKSGVAGDQADSTTTTSSSETQDGNTNHGEYKDTTNENPEKNSGQEGTQESGSSSNTFDN 593
S + A++ + S + ++++ + ++ ++ N DN
Sbjct: 4553 MLSDIDAHDANNDVDSKKSGFIGKRKSEEDFENELSNEHFSADQEDDSEIQSLIENIEDN 4612
Query: 594 KDAASNKVQLTTTSDTSSEQKKDESSSAESKSESSQND 631
AS + + E+ +ES KSE S D
Sbjct: 4613 PPDAS--------ASLTPERSLEESRELWHKSEISTAD 4642
Score = 124 bits (310), Expect = 1e-27
Identities = 113/594 (19%), Positives = 245/594 (41%), Gaps = 40/594 (6%)
Query: 228 ESSEEKSHLENEENKDEEKSKQENEEIKDGEKI----QQENEENKDEEKSQQENEENKDE 283
E ++K+ E D E ++ N++++ E + Q EN+E +D+++ ENE++ E
Sbjct: 4051 EEVDDKNLQEGTGLGDGEGAQNNNKDVEQDEDLTEDAQNENKEQQDKDERDDENEDDAVE 4110
Query: 284 EKSQQENELKKNEGGEKETGEITEEKSKQENEETSETNSKDK---ENEESNQNGSDAKEQ 340
+ EL+ GE+ E T+ + ++ +EE + N D +++ + SD ++
Sbjct: 4111 MEGDMAGELEDLSNGEENDDEDTDSEEEELDEEIDDLNEDDPNAIDDKMWDDKASDNSKE 4170
Query: 341 VGENHEQDSKQGTEETNGTEGGEKEEHDKIKEDTSSDNQVQDG----EKNNEAREENYSG 396
+ D K E+ E E++ +K D N +DG E + A EEN G
Sbjct: 4171 KDTDQNLDGKNQEEDVQAAENDEQQRDNKEGGD-EDPNAPEDGDEEIENDENAEEENDVG 4229
Query: 397 DNASSAVVDNKSQESSNKTE-EQFDKKEKNEFELESQKNSNET--TESTDSTITQNSQGN 453
+ + +N E E D E + E +++ + ++ + + GN
Sbjct: 4230 EQEDEVKDEEGEDLEANVPEIETLDLPEDMNLDSEHEESDEDVDMSDGMPDDLNKEEVGN 4289
Query: 454 ESEKDQAQT------ENDTPKGSASESDEQKQEQEQNNTTKDDVQTTDTSSQNGNDTTEK 507
E E+ + ++ END P G ++ E + ++ ++DV T+ + + +
Sbjct: 4290 EDEEVKQESGIESDNENDEP-GPEEDAGETETALDEEEGAEEDVDMTNDEGKEDEENGPE 4348
Query: 508 QNETSEDANSKKEDSSALNTTPNNEDSKSGVAG--DQADSTTTTSSSETQDGNTNHGEYK 565
+ S++ K++ + N E + G+ G ++AD+ + Q + + G
Sbjct: 4349 EQAMSDEEELKQDAAMEENKEKGGEQNTEGLDGVEEKADTEDIDQEAAVQQDSGSKGAGA 4408
Query: 566 DTTNENPEKNSGQEGTQES-------GSSSNTFDNKDAASNKVQLTTTSDTSSEQKKDES 618
D T+ + + G GT ++ + N ++++ A+ ++ S +++ +
Sbjct: 4409 DATDTQEQDDVGGSGTTQNTYEEDQEDVTKNNEESREEATAALKQLGDSMKEYHRRRQDI 4468
Query: 619 SSAESKSESSQNDNANSGQ---------SNTTSDESANDNKDSSQVTTSSENSAEGNSNT 669
A++ E +N N+ + +NT +D A + Q+ T E+ A +
Sbjct: 4469 KEAQTNGEEDENLEKNNERPDEFEHVEGANTETDTQALGSATQDQLQTIDEDMAIDDDRE 4528
Query: 670 ENNSDENQNDSKNNENTNDSGNTSNDANVNENQNENAAQTKTSENEGDAQNESVESKKEN 729
E D+ + ++ D ++++ + N +K S G ++E + +
Sbjct: 4529 EQEVDQKELVEDADDEKMDIDEEEMLSDIDAHDANNDVDSKKSGFIGKRKSEEDFENELS 4588
Query: 730 NESAHKDVDNNSNSNDQGSSDTSVTQDDKESRVDLGTLPESNGESHHNDVSSAE 783
NE D +++S + D S +L ES H +++S+A+
Sbjct: 4589 NEHFSADQEDDSEIQSLIENIEDNPPDASASLTPERSLEESRELWHKSEISTAD 4642
Score = 124 bits (310), Expect = 1e-27
Identities = 137/619 (22%), Positives = 264/619 (42%), Gaps = 74/619 (11%)
Query: 87 ADELDNKH-DEQTKLDDVNGVEDNS---EHKEDSVEQ-ESEESSQNAKTDLEGEQHTEKV 141
++E+D+K+ E T L D G ++N+ E ED E ++E Q K + + E + V
Sbjct: 4050 SEEVDDKNLQEGTGLGDGEGAQNNNKDVEQDEDLTEDAQNENKEQQDKDERDDENEDDAV 4109
Query: 142 DEEND---------NAENKENESVEKENEEIKKEVEDTETGE--SIEEK----SHLENEE 186
+ E D N E ++E + E EE+ +E++D + +I++K +N +
Sbjct: 4110 EMEGDMAGELEDLSNGEENDDEDTDSEEEELDEEIDDLNEDDPNAIDDKMWDDKASDNSK 4169
Query: 187 SKETGEISEEKSHLENEESKETGESSEEKSHLENEESKETGESSEEKSHLENEENKDEEK 246
K+T + + K+ E+ ++ E E + +E+ + EE +EN+EN +EE
Sbjct: 4170 EKDTDQNLDGKNQEEDVQAAENDEQQRDNKEGGDEDPNAPEDGDEE---IENDENAEEEN 4226
Query: 247 SKQENE-EIKDGEKIQQENEENKDE-EKSQQENEENKDEEKSQQENELKKNEG-----GE 299
E E E+KD E ++ E N E E + N D E + + ++ ++G +
Sbjct: 4227 DVGEQEDEVKDEE--GEDLEANVPEIETLDLPEDMNLDSEHEESDEDVDMSDGMPDDLNK 4284
Query: 300 KETGEITEEKSKQENEETSETNSKDKENEESNQNGSDAKEQVGENHEQD--SKQGTE-ET 356
+E G EE ++ E+ N + E++ + + E+ G + D + +G E E
Sbjct: 4285 EEVGNEDEEVKQESGIESDNENDEPGPEEDAGETETALDEEEGAEEDVDMTNDEGKEDEE 4344
Query: 357 NGTEGGEKEEHDKIKEDTS-SDNQVQDGEKNNE----AREENYSGDNASSAVVDNKSQE- 410
NG E + +++K+D + +N+ + GE+N E E+ + D A V S
Sbjct: 4345 NGPEEQAMSDEEELKQDAAMEENKEKGGEQNTEGLDGVEEKADTEDIDQEAAVQQDSGSK 4404
Query: 411 ----SSNKTEEQFD----KKEKNEFELESQKNSNETTESTDSTITQNSQGNESEKDQAQT 462
+ T+EQ D +N +E + + + ES + Q +S K+ +
Sbjct: 4405 GAGADATDTQEQDDVGGSGTTQNTYEEDQEDVTKNNEESREEATAALKQLGDSMKEYHRR 4464
Query: 463 ENDTPKGSASESDEQKQEQEQNNTTKDDVQTTDTSSQNGNDTTEKQNETSEDANSKKEDS 522
D + A + E+ + E+NN D+ + + + DT + T + + ED
Sbjct: 4465 RQDIKE--AQTNGEEDENLEKNNERPDEFEHVE-GANTETDTQALGSATQDQLQTIDEDM 4521
Query: 523 SALNTTPNNEDSKSGVAGDQADSTTTTSSSETQDGNTNHGEYKDTTNENPEKNSGQEGTQ 582
+ + E + + D D E H D N+ K SG G +
Sbjct: 4522 AIDDDREEQEVDQKELVEDADDEKMDIDEEEMLSDIDAH----DANNDVDSKKSGFIGKR 4577
Query: 583 ESGSSSNTFDNKDAASNKVQLTTTSDTSSEQKKDESSSAESKSESSQNDNANSGQSNTTS 642
+ S F+N+ + S++Q+ D S +S E+ + DN ++ T
Sbjct: 4578 K---SEEDFENE---------LSNEHFSADQEDD--SEIQSLIENIE-DNPPDASASLTP 4622
Query: 643 DESANDNKD---SSQVTTS 658
+ S ++++ S+++T+
Sbjct: 4623 ERSLEESRELWHKSEISTA 4641
Score = 124 bits (310), Expect = 1e-27
Identities = 134/633 (21%), Positives = 259/633 (40%), Gaps = 69/633 (10%)
Query: 110 SEHKEDSVEQESE-----ESSQNAKTDLEGEQHTEKVDEENDNAENKENESVEKENEEIK 164
SE +D QE E +QN D+E ++ + D +N+N E ++ + + ENE+
Sbjct: 4050 SEEVDDKNLQEGTGLGDGEGAQNNNKDVEQDEDLTE-DAQNENKEQQDKDERDDENEDDA 4108
Query: 165 KEVEDTETGESIEEKSHLENEESKETGEISEEKSHLENEESKETGESSEEKSHLENEESK 224
E+E GE +E+ S+ E + ++T SEE+ E EE L ++
Sbjct: 4109 VEMEGDMAGE-LEDLSNGEENDDEDTD--SEEE------------ELDEEIDDLNEDDPN 4153
Query: 225 ETGESSEEKSHLENEENKDEE-----KSKQENEEIKDGEKIQQENEENKDEEKSQQENEE 279
+ + +N + KD + K+++E+ + + ++ Q++N+E DE+ + E
Sbjct: 4154 AIDDKMWDDKASDNSKEKDTDQNLDGKNQEEDVQAAENDEQQRDNKEGGDEDPNA---PE 4210
Query: 280 NKDEEKSQQENELKKNEGGEKETGEITEEKSKQENEETSETNSKDKENEESNQNGSDAKE 339
+ DEE EN ++N+ GE+ E++ K E E E N + E + ++ + E
Sbjct: 4211 DGDEEIENDENAEEENDVGEQ------EDEVKDEEGEDLEANVPEIETLDLPEDMNLDSE 4264
Query: 340 QVGENHEQDSKQG-TEETNGTEGGEKEEHDKIKEDTSSDNQVQDGEKNNEAREENYSGDN 398
+ + D G ++ N E G ++E K + SDN+ + +A E + D
Sbjct: 4265 HEESDEDVDMSDGMPDDLNKEEVGNEDEEVKQESGIESDNENDEPGPEEDAGETETALDE 4324
Query: 399 ASSAVVDNKSQESSNKTEEQFDKKEKNEFELESQKNSNETTESTDSTITQNSQGNESEKD 458
A D K +E+ +E+ + E K E+ + QN++G + ++
Sbjct: 4325 EEGAEEDVDMTNDEGKEDEENGPEEQAMSDEEELKQDAAMEENKEKGGEQNTEGLDGVEE 4384
Query: 459 QAQTENDTPKGSASESDEQKQEQEQNNTTKDDVQTTDTSSQN---GNDTTEKQNETSEDA 515
+A TE + D++ Q+ + + TDT Q+ G+ TT+
Sbjct: 4385 KADTE---------DIDQEAAVQQDSGSKGAGADATDTQEQDDVGGSGTTQ--------- 4426
Query: 516 NSKKEDSSALNTTPNNEDSKSGVAGDQADSTTTTSSSETQDGNTNHGEYKDTTNENPEKN 575
N+ +ED + T NNE+S+ + + + + +EN EKN
Sbjct: 4427 NTYEEDQE--DVTKNNEESREEATAALKQLGDSMKEYHRRRQDIKEAQTNGEEDENLEKN 4484
Query: 576 SGQEGTQESGSSSNTFDNKDA--ASNKVQLTTTSDTSSEQKKDESSSAESKS--ESSQND 631
+ + E +NT + A ++ + QL T + + E + K E + ++
Sbjct: 4485 NERPDEFEHVEGANTETDTQALGSATQDQLQTIDEDMAIDDDREEQEVDQKELVEDADDE 4544
Query: 632 NANSGQSNTTSDESANDNKDSSQVTTSSENSAEGNSNTENNSDENQNDSKNNENTNDSGN 691
+ + SD A+D ++ G + ++ +N+ N + D +
Sbjct: 4545 KMDIDEEEMLSDIDAHD------ANNDVDSKKSGFIGKRKSEEDFENELSNEHFSADQED 4598
Query: 692 TSNDANVNENQNENAAQTKTSENEGDAQNESVE 724
S ++ EN +N S + ES E
Sbjct: 4599 DSEIQSLIENIEDNPPDASASLTPERSLEESRE 4631
Score = 108 bits (271), Expect = 4e-23
Identities = 112/474 (23%), Positives = 202/474 (41%), Gaps = 66/474 (13%)
Query: 77 DARHKEDEEEADELDNKH---DEQTKLDDVNGVEDNSEHKEDSVEQESEES--------- 124
D + ++++E DE N DE+ + D+ E++ +ED V+ E E
Sbjct: 4192 DEQQRDNKEGGDEDPNAPEDGDEEIENDENAEEENDVGEQEDEVKDEEGEDLEANVPEIE 4251
Query: 125 ----SQNAKTDLEGEQHTEKVDEENDNAENKENESVEKENEEIKKE---VEDTETGESIE 177
++ D E E+ E VD + ++ E V E+EE+K+E D E E
Sbjct: 4252 TLDLPEDMNLDSEHEESDEDVDMSDGMPDDLNKEEVGNEDEEVKQESGIESDNENDEPGP 4311
Query: 178 EKSHLENEESKETGEISEEKSHLENEESKETGESSEEKSHLENEESKETG---ESSEEKS 234
E+ E E + + E +EE + N+E KE E+ E+ + +EE + E ++EK
Sbjct: 4312 EEDAGETETALDEEEGAEEDVDMTNDEGKEDEENGPEEQAMSDEEELKQDAAMEENKEKG 4371
Query: 235 HLENEENKDEEKSKQENEEIKDGEKIQQEN-------------EENKDEEKSQQENEENK 281
+N E D + K + E+I +QQ++ E++ +N +
Sbjct: 4372 GEQNTEGLDGVEEKADTEDIDQEAAVQQDSGSKGAGADATDTQEQDDVGGSGTTQNTYEE 4431
Query: 282 DEEKSQQENELKKNE--GGEKETGEITEEKSKQENE-ETSETNSKDKENEESNQNGSDAK 338
D+E + NE + E K+ G+ +E ++ + + ++TN ++ EN E N D
Sbjct: 4432 DQEDVTKNNEESREEATAALKQLGDSMKEYHRRRQDIKEAQTNGEEDENLEKNNERPDEF 4491
Query: 339 EQV-GENHEQDSK------QGTEETNGTEGGEKEEHDKIKEDTSSDNQVQDGEKNNEARE 391
E V G N E D++ Q +T + ++ ++ + D + D EK + E
Sbjct: 4492 EHVEGANTETDTQALGSATQDQLQTIDEDMAIDDDREEQEVDQKELVEDADDEKMDIDEE 4551
Query: 392 ENYSGDNASSAVVDNKSQES----SNKTEEQFDKKEKNEFELESQKNSNETTESTDSTIT 447
E S +A A D S++S K+EE F+ + NE Q++ +E ++
Sbjct: 4552 EMLSDIDAHDANNDVDSKKSGFIGKRKSEEDFENELSNEHFSADQEDDSEIQSLIEN--- 4608
Query: 448 QNSQGNESEKDQAQTENDTPKGSASESDEQKQEQEQNNTTKDDVQTTDTSSQNG 501
E++ P SAS + E+ E+ + K ++ T D S+ G
Sbjct: 4609 --------------IEDNPPDASASLTPERSLEESRELWHKSEISTADLVSRLG 4648
Score = 75.5 bits (184), Expect = 5e-13
Identities = 80/331 (24%), Positives = 151/331 (45%), Gaps = 41/331 (12%)
Query: 67 KPRVEETSVIDARHKEDEEEADELDNKHDEQTKLDDVNGVEDNSEHKEDSVEQESEESSQ 126
+P EE + ++EE A+E + +++ K D+ NG E+ + E+ ++Q++
Sbjct: 4308 EPGPEEDAGETETALDEEEGAEEDVDMTNDEGKEDEENGPEEQAMSDEEELKQDAAMEEN 4367
Query: 127 NAKTDLEGEQHTEKVD--EENDNAENKENESVEKENEEIK---KEVEDTETGESIEEKSH 181
K GEQ+TE +D EE + E+ + E+ +++ K + DT+ + +
Sbjct: 4368 KEK---GGEQNTEGLDGVEEKADTEDIDQEAAVQQDSGSKGAGADATDTQEQDDVGGSGT 4424
Query: 182 LEN---EESKETGEISEEKSHLENEESKETGESSEEKSHLENEESKETGESSEEKSHLE- 237
+N E+ ++ + +EE K+ G+S +E H ++ KE + EE +LE
Sbjct: 4425 TQNTYEEDQEDVTKNNEESREEATAALKQLGDSMKE-YHRRRQDIKEAQTNGEEDENLEK 4483
Query: 238 NEENKDE----EKSKQENEEIKDGEKIQQE----------NEENKDEEKSQQENEENKDE 283
N E DE E + E + G Q + +++ +++E Q+E E+ D+
Sbjct: 4484 NNERPDEFEHVEGANTETDTQALGSATQDQLQTIDEDMAIDDDREEQEVDQKELVEDADD 4543
Query: 284 EKSQQENEL---------KKNEGGEKETGEITEEKSKQ--ENEETSETNSKDKENEESNQ 332
EK + E N+ K++G I + KS++ ENE ++E S D+E++ Q
Sbjct: 4544 EKMDIDEEEMLSDIDAHDANNDVDSKKSGFIGKRKSEEDFENELSNEHFSADQEDDSEIQ 4603
Query: 333 NGSDAKEQVGENHEQDSKQGTEETNGTEGGE 363
+ E + +N S T E + E E
Sbjct: 4604 S---LIENIEDNPPDASASLTPERSLEESRE 4631
Score = 73.6 bits (179), Expect = 2e-12
Identities = 71/314 (22%), Positives = 121/314 (37%), Gaps = 32/314 (10%)
Query: 474 SDEQKQEQEQNNTTKDDVQTTDTSSQNGNDTTEKQNETSEDA-NSKKEDSSALNTTPNNE 532
S+E + Q T D + +QN N E+ + +EDA N KE NE
Sbjct: 4050 SEEVDDKNLQEGTGLGDGE----GAQNNNKDVEQDEDLTEDAQNENKEQQDKDERDDENE 4105
Query: 533 DSKSGVAGDQADSTTTTSSSETQDGNTNHGEYKDTTNENPEKNSGQEGTQESGSSSNTFD 592
D + GD A S+ E D E ++ E + N + +D
Sbjct: 4106 DDAVEMEGDMAGELEDLSNGEENDDEDTDSEEEELDEEIDDLNE----DDPNAIDDKMWD 4161
Query: 593 NKDAASNKVQLTTTSDTSSEQKKDESSSAESKSESSQNDNANSGQSNTTSDESANDNKDS 652
+K + ++K + T D + + K E ++++ Q DN G DE N +D
Sbjct: 4162 DKASDNSKEKDT---DQNLDGKNQEEDVQAAENDEQQRDNKEGG------DEDPNAPEDG 4212
Query: 653 SQVTTSSENSAEGNSNTENN---SDENQNDSKNNENTNDSGNTSNDANVNENQNENAAQT 709
+ + EN+ E N E DE D + N ++ + D N++ E+
Sbjct: 4213 DEEIENDENAEEENDVGEQEDEVKDEEGEDLEANVPEIETLDLPEDMNLDSEHEESDEDV 4272
Query: 710 KTSE------NEGDAQNESVESKKENNESAHKDVDNNSNSNDQGSSDTSV-----TQDDK 758
S+ N+ + NE E K+E+ + + D D G ++T++ ++D
Sbjct: 4273 DMSDGMPDDLNKEEVGNEDEEVKQESGIESDNENDEPGPEEDAGETETALDEEEGAEEDV 4332
Query: 759 ESRVDLGTLPESNG 772
+ D G E NG
Sbjct: 4333 DMTNDEGKEDEENG 4346
Score = 40.8 bits (94), Expect = 0.014
Identities = 32/150 (21%), Positives = 69/150 (45%), Gaps = 7/150 (4%)
Query: 49 GASTKTGNEVVKLGRKDLKPRVEETSVIDARHKEDEEEADEL-DNKHDEQTKLDDVNGVE 107
GA+T+T + + +D ++E ID +E E + EL ++ DE+ +D+ +
Sbjct: 4496 GANTETDTQALGSATQDQLQTIDEDMAIDDDREEQEVDQKELVEDADDEKMDIDEEEMLS 4555
Query: 108 DNSEHKEDSVEQESEESSQNAKTDLEGEQHTEKVDEENDNAENKENESVEKENEEIKKEV 167
D H ++ + +S++S K E E ++ E+ +A+ +++ ++ E I+
Sbjct: 4556 DIDAHDANN-DVDSKKSGFIGKRKSE-EDFENELSNEHFSADQEDDSEIQSLIENIEDNP 4613
Query: 168 EDTETG----ESIEEKSHLENEESKETGEI 193
D S+EE L ++ T ++
Sbjct: 4614 PDASASLTPERSLEESRELWHKSEISTADL 4643
>VG48_SHV21 (Q01033) Hypothetical gene 48 protein
Length = 797
Score = 124 bits (311), Expect = 1e-27
Identities = 98/435 (22%), Positives = 192/435 (43%), Gaps = 50/435 (11%)
Query: 82 EDEEEA----DELDNKHDEQTKLDDVNGVEDNSEHKEDSVEQESEESSQNAKTDLEG-EQ 136
EDE E DE+D++ LDD +S S Q D + E+
Sbjct: 338 EDEVELCISDDEVDSEDGNLCVLDD------------ESESVNSVALRQVLTVDKQANEK 385
Query: 137 HTEKVDEENDNAENKENESVEKENEEIKKEVEDTETGESIEEKSHLENEESKETGEISEE 196
+K+ +++D+ ++++ + E ENEE ++ E+ E + +EK
Sbjct: 386 EYKKIIDKSDDRDDRDKDEYELENEEYNRDEEEDEGEDEEDEKD---------------- 429
Query: 197 KSHLENEESKETGESSEEKSHLENEESKETGESSEEKSHLENEENKDEEKSKQENEEIKD 256
E EE ++ G+ E++ E E+ + G+ +E +E+ +E++ + E +E +
Sbjct: 430 ----EKEEGEDEGDDGEDEGEDEGEDEGDEGDEGDEGEDEGEDEDDEEDEGEDEGDEGDE 485
Query: 257 GEKIQQENEENKDEEKSQQENEENKDEEKSQQENELKKNEGGEKETGEITEEKSKQENEE 316
GE E +E +DE E +E KDE E + + +EG E + G+ E++ + E +E
Sbjct: 486 GEDEGDEGDEGEDE---GDEGDEGKDEGDEGDEGKDEGDEGDEGDEGDEGEDEWEDEGDE 542
Query: 317 -TSETNSKDKENEESNQNGSDAKEQVGENHEQDSKQGTEETNGTEGGEKEEHDKIKEDTS 375
E + + E +E G D ++ GE+ +D E+ EG E E+ + + D
Sbjct: 543 GEDEGDEGEDEGDEGEDEGEDEGDE-GEDEGEDEGDEGEDEGEDEGDEGEDEGEDEGDEG 601
Query: 376 SDNQVQDGEKNNEAREENYSGDNASSAVVDNKSQESSNKTEEQFDKKEKNEFELESQKNS 435
D +G++ +E +E G++ ++ ++ ++ E++ D+ E E E + +
Sbjct: 602 EDEGEDEGDEGDEGEDEGDEGEDEG-----DEGEDEGDEGEDEGDEGEDEGDEGEDEGDE 656
Query: 436 NETTESTDSTITQNSQGNESEKDQAQTENDTPKG-SASESDEQKQEQEQNNTTKDDVQTT 494
E + D +G+E E + + E++ +G E DE + +++ +D
Sbjct: 657 GE--DEGDEGDEGEDEGDEGEDEGDEGEDEGDEGDEGDEGDEGDEGEDEGEDEGEDEGDE 714
Query: 495 DTSSQNGNDTTEKQN 509
T + GN QN
Sbjct: 715 GTKDKEGNANKVVQN 729
Score = 123 bits (308), Expect = 2e-27
Identities = 83/371 (22%), Positives = 174/371 (46%), Gaps = 27/371 (7%)
Query: 71 EETSVIDARHKEDEEEADELDNKHDEQTKLDDVNGVEDNSEHKEDSVEQESEESSQNAKT 130
E +ID D+ + DE + +++E + ++ ED E +ED +++ E +
Sbjct: 386 EYKKIIDKSDDRDDRDKDEYELENEEYNRDEE----EDEGEDEEDEKDEKEEGEDEGDDG 441
Query: 131 DLEGEQHTEKVDEENDNAENKENESVEKENEEIKKEVEDTETGESIEEKSHLENEESKET 190
+ EGE E +E D + E+E ++++EE + E E E E +E E +E ++
Sbjct: 442 EDEGEDEGEDEGDEGDEGDEGEDEGEDEDDEEDEGEDEGDEGDEGEDEGD--EGDEGEDE 499
Query: 191 GEISEEKSHLENEESKETGESSEEKSHLENEESKETGESSEEKSHLENEENKDEEKSKQE 250
G+ E +E K+ G+ +E E +E E E E + E+E ++ E++ +
Sbjct: 500 GD--------EGDEGKDEGDEGDEGKD-EGDEGDEGDEGDEGEDEWEDEGDEGEDEGDEG 550
Query: 251 NEEIKDGEKIQQENEENKDEEKSQQENEENKDEEKSQQENELKKNEGGEKETGEITEEKS 310
+E +GE E E+ DE + + E+E ++ E++ + E + ++EG ++ G+ E++
Sbjct: 551 EDEGDEGE---DEGEDEGDEGEDEGEDEGDEGEDEGEDEGDEGEDEG--EDEGDEGEDEG 605
Query: 311 KQENEETSETNSKDKENEESNQNGSDAKEQVGENHEQDSKQGTEETNGTEGGEKEEHDKI 370
+ E +E E + E E+ G D ++ + ++ +G E + + GE E +
Sbjct: 606 EDEGDEGDEGEDEGDEGEDEGDEGEDEGDEGEDEGDEGEDEGDEGEDEGDEGEDEGDEGD 665
Query: 371 KEDTSSDNQVQDGEKNNEAREENYSGDNASSAVVDNKSQESSNKTEEQFDKKEKNEFELE 430
+ + D +G++ + +E GD D E ++ E++ D+ K +
Sbjct: 666 EGEDEGDEGEDEGDEGEDEGDEGDEGDEGDEG--DEGEDEGEDEGEDEGDEGTK-----D 718
Query: 431 SQKNSNETTES 441
+ N+N+ ++
Sbjct: 719 KEGNANKVVQN 729
Score = 123 bits (308), Expect = 2e-27
Identities = 92/394 (23%), Positives = 186/394 (46%), Gaps = 28/394 (7%)
Query: 71 EETSVIDARHKEDEEEADELDNKHDEQTKLDDVNGVEDNSEHKEDSVEQESEESSQNAKT 130
+E + + + DEEE + D + ++ K + + +D + ED E E +E + +
Sbjct: 403 DEYELENEEYNRDEEEDEGEDEEDEKDEKEEGEDEGDDGEDEGEDEGEDEGDEGDEGDEG 462
Query: 131 DLEGEQHTEKVDE------ENDNAENKENESVEKENEEIKKEVEDTETGESIEEKSHLEN 184
+ EGE ++ DE E D E++ +E E E+E + + E E E K +
Sbjct: 463 EDEGEDEDDEEDEGEDEGDEGDEGEDEGDEGDEGEDEGDEGDEGKDEGDEGDEGKDEGDE 522
Query: 185 EESKETGEISEEKSHLENEESKETGESSEEKSHLENEESKETGESSEEKSHLENEENKDE 244
+ + G+ E++ E +E ++ G+ E++ +E ++ G+ E++ E +E +DE
Sbjct: 523 GDEGDEGDEGEDEWEDEGDEGEDEGDEGEDEGDEGEDEGEDEGDEGEDEGEDEGDEGEDE 582
Query: 245 ---EKSKQENEEIKDGEKIQQENEENKDE-EKSQQENEENKDE-EKSQQENELKKNEGGE 299
E + E+E +G++ + E E+ DE ++ + E +E +DE ++ + E + ++EG E
Sbjct: 583 GEDEGDEGEDEGEDEGDEGEDEGEDEGDEGDEGEDEGDEGEDEGDEGEDEGDEGEDEGDE 642
Query: 300 KETGEITEEKSKQENEETSETNSKDKENEESNQNGSDAKEQVGENHEQDSKQGTEETNGT 359
GE ++ + E +E + + E E+ G D G+ E + +G E G
Sbjct: 643 ---GEDEGDEGEDEGDEGEDEGDEGDEGEDEGDEGEDE----GDEGEDEGDEGDEGDEGD 695
Query: 360 EGGEKEEHDKIKEDTSSDNQVQDGEKN-NEAREENYSGDN----ASSAVVDNKS-QESSN 413
EG E E+ + + + D +D E N N+ + + N ++ ++V NKS + +
Sbjct: 696 EGDEGEDEGEDEGEDEGDEGTKDKEGNANKVVQNPFDYYNWLQKSTLSIVHNKSIHATEH 755
Query: 414 KTEEQFDKKEKNEFE----LESQKNSNETTESTD 443
E+Q FE ++ +N+ E+ +T+
Sbjct: 756 MLEDQLQHSLTASFETHLYIKPFRNTKESQAATN 789
Score = 105 bits (263), Expect = 4e-22
Identities = 103/467 (22%), Positives = 194/467 (41%), Gaps = 52/467 (11%)
Query: 146 DNAENKENESVEKENEEIKKEVEDTETGESIEEKSHLENEESKETGEISEEKSHLENEES 205
D+ + +E + + +E++ + D E L++E + ++ + +
Sbjct: 324 DHKLSPVSEYEDFDEDEVELCISDDEVDSEDGNLCVLDDESESVNSVALRQVLTVDKQAN 383
Query: 206 KETGESSEEKSHLENEESKETGESSEEKSHLENEENK--DEEKSKQENEEIKDGEKIQQE 263
++ + +KS ++ K+ E E+ + + EE++ DEE K E EE +D E
Sbjct: 384 EKEYKKIIDKSDDRDDRDKDEYELENEEYNRDEEEDEGEDEEDEKDEKEEGED------E 437
Query: 264 NEENKDEEKSQQENEENKDEEKSQQENELKKNEGGEKETGEITEEKSKQENEETSETNSK 323
++ +DE + + E+E ++ +E + E+E GE E E E++ + E +E E +
Sbjct: 438 GDDGEDEGEDEGEDEGDEGDEGDEGEDE------GEDEDDE--EDEGEDEGDEGDEGEDE 489
Query: 324 DKENEESNQNGSDAKEQVGENHEQDSKQGTEETNGTEGGEKEEHDKIKEDTSSDNQVQDG 383
E +E G + E E E D +G +E G EG E +E D+ ED D +
Sbjct: 490 GDEGDEGEDEGDEGDEGKDEGDEGD--EGKDE--GDEGDEGDEGDE-GEDEWEDEGDEGE 544
Query: 384 EKNNEAREENYSGDNASSAVVDNKSQESSNKTEEQFDKKEKNEFELESQKNSNETTESTD 443
++ +E +E G++ D E ++ +E D+ E E E + +E E D
Sbjct: 545 DEGDEGEDEGDEGEDEGEDEGDEGEDEGEDEGDEGEDEGEDEGDEGEDE-GEDEGDEGED 603
Query: 444 STITQNSQGNESEK--DQAQTENDTPKGSASESDEQKQEQEQNNTTKDDVQTTDTSSQNG 501
+ +G+E E D+ + E D + E +++ E E +D +
Sbjct: 604 EGEDEGDEGDEGEDEGDEGEDEGDEGEDEGDEGEDEGDEGEDEGDEGEDEGDEGEDEGDE 663
Query: 502 NDTTEKQNETSEDANSKKEDSSALNTTPNNEDSKSGVAGDQADSTTTTSSSETQDGNTNH 561
D E + + ED + ED ++ G GD+ D E +D +
Sbjct: 664 GDEGEDEGDEGEDEGDEGED--------EGDEGDEGDEGDEGD--------EGEDEGEDE 707
Query: 562 GEYKDTTNENPEKNSGQEGTQE-SGSSSNTFDNKDAASNKVQLTTTS 607
GE + G EGT++ G+++ N N +Q +T S
Sbjct: 708 GE-----------DEGDEGTKDKEGNANKVVQNPFDYYNWLQKSTLS 743
Score = 90.9 bits (224), Expect = 1e-17
Identities = 82/434 (18%), Positives = 169/434 (38%), Gaps = 58/434 (13%)
Query: 313 ENEETSETNSKDKENEESNQNGSDAKEQV----GENHEQDSKQGTEETNGTEGGEKEEHD 368
++E SE + ++ES S A QV + +E++ K+ ++++ + +K+E++
Sbjct: 347 DDEVDSEDGNLCVLDDESESVNSVALRQVLTVDKQANEKEYKKIIDKSDDRDDRDKDEYE 406
Query: 369 KIKEDTSSDNQVQDGEKNNEAREENYSGDNASSAVVDNKSQESSNKTEEQFDK-KEKNEF 427
E+ + D + +GE + ++E G++ D+ E ++ E++ D+ E +E
Sbjct: 407 LENEEYNRDEEEDEGEDEEDEKDEKEEGEDEG----DDGEDEGEDEGEDEGDEGDEGDEG 462
Query: 428 ELESQKNSNETTESTDSTITQNSQGNESEKDQAQTENDTPKGSASESDEQKQEQEQNNTT 487
E E + +E E D + +G+E E + E D + E DE K E ++ +
Sbjct: 463 EDEGEDEDDEEDEGED----EGDEGDEGEDEG--DEGDEGEDEGDEGDEGKDEGDEGDEG 516
Query: 488 KDDVQTTDTSSQN--GNDTTEKQNETSEDANSKKEDSSALNTTPNNEDSKSGVAGDQADS 545
KD+ D + G D E + + ED + ED GD+ +
Sbjct: 517 KDEGDEGDEGDEGDEGEDEWEDEGDEGEDEGDEGEDE-----------------GDEGE- 558
Query: 546 TTTTSSSETQDGNTNHGEYKDTTNENPEKNSGQEGTQESGSSSNTFDNKDAASNKVQLTT 605
+ GE + E+ ++ G EG E + + +D ++
Sbjct: 559 --------------DEGEDEGDEGEDEGEDEGDEGEDEGEDEGD--EGEDEGEDE----- 597
Query: 606 TSDTSSEQKKDESSSAESKSESSQNDNANSGQSNTTSDESANDNKDSSQVTTSSENSAEG 665
D ++ +DE + + + DE ++ + E+ +
Sbjct: 598 -GDEGEDEGEDEGDEGDEGEDEGDEGEDEGDEGEDEGDEGEDEGDEGEDEGDEGEDEGDE 656
Query: 666 NSNTENNSDENQNDSKNNENTNDSGNTSNDANVNENQNENAAQTKTSENEGDAQNESVES 725
+ + DE +++ E+ D G D +E + E E + ++E E
Sbjct: 657 GEDEGDEGDEGEDEGDEGEDEGDEGEDEGDEG-DEGDEGDEGDEGEDEGEDEGEDEGDEG 715
Query: 726 KKENNESAHKDVDN 739
K+ +A+K V N
Sbjct: 716 TKDKEGNANKVVQN 729
Score = 89.4 bits (220), Expect = 3e-17
Identities = 70/365 (19%), Positives = 140/365 (38%), Gaps = 25/365 (6%)
Query: 386 NNEAREENYSGDNASSAVVDNKSQESSNKTEEQFDKKEKNEFELESQKNSNETTESTDST 445
+ +A E+ Y S D++ ++ E++++ E+ + + + +E E D
Sbjct: 379 DKQANEKEYKKIIDKSDDRDDRDKDEYELENEEYNRDEEEDEGEDEEDEKDEKEEGED-- 436
Query: 446 ITQNSQGNESEKDQAQTENDTPKGSASESDEQKQEQEQNNTTKDDVQTTDTSSQNGNDTT 505
+ G + +D+ + E D DE + E ++ + +D+ D G++
Sbjct: 437 --EGDDGEDEGEDEGEDEGDEGDEGDEGEDEGEDEDDEEDEGEDEGDEGDEGEDEGDEGD 494
Query: 506 EKQNETSEDANSKKEDSSALNTTPNNEDSKSGVAGDQADSTTTTSSSETQDGNTNHGEYK 565
E ++E E K E ++ G GD+ + E +D + GE +
Sbjct: 495 EGEDEGDEGDEGKDEGDEGDEGKDEGDEGDEGDEGDEGEDEWEDEGDEGEDEG-DEGEDE 553
Query: 566 DTTNENPEKNSGQEGTQESGSSSNTFDNKDAASNKVQLTTTSDTSSEQKKDESSSAESKS 625
E+ ++ G EG E + + +D ++ D ++ +DE E +
Sbjct: 554 GDEGEDEGEDEGDEGEDEGEDEGD--EGEDEGEDE------GDEGEDEGEDEGDEGEDEG 605
Query: 626 ESSQNDNANSGQSNTTSDESANDNKDSSQVTTSSENSAEGNSNTENNSDENQNDSKNNEN 685
E + D + G+ E D + E EG+ E+ DE +++ E+
Sbjct: 606 ED-EGDEGDEGEDEGDEGEDEGDEGEDE----GDEGEDEGDEG-EDEGDEGEDEGDEGED 659
Query: 686 TNDSGNTSNDANVNENQNENAAQTKTSENEGDAQNESVESKKENNESAHKDVDNNSNSND 745
D G+ D +E + E+EGD +E E E +E + D + D
Sbjct: 660 EGDEGDEGEDEG-----DEGEDEGDEGEDEGDEGDEGDEG-DEGDEGEDEGEDEGEDEGD 713
Query: 746 QGSSD 750
+G+ D
Sbjct: 714 EGTKD 718
Score = 86.3 bits (212), Expect = 3e-16
Identities = 70/393 (17%), Positives = 147/393 (36%), Gaps = 34/393 (8%)
Query: 391 EENYSGDNASSAVVDNKSQESSNKTEEQFDKKEKNEFELESQKNSNETTESTDSTITQNS 450
++ ++ + V+D++S+ ++ Q +K E E +K I ++
Sbjct: 347 DDEVDSEDGNLCVLDDESESVNSVALRQVLTVDKQANEKEYKK-----------IIDKSD 395
Query: 451 QGNESEKDQAQTENDTPKGSASESDEQKQEQEQNNTTKDDVQTTDTSSQNGNDTTEKQNE 510
++ +KD+ + EN+ DE++ E E KD+ + + +G D E + E
Sbjct: 396 DRDDRDKDEYELENEE-----YNRDEEEDEGEDEEDEKDEKEEGEDEGDDGEDEGEDEGE 450
Query: 511 TSEDANSKKEDSSALNTTPNNEDSKSGVAGDQADSTTTTSSSETQDGNTNHGEYKDTTNE 570
D + ++ ++E+ + GD+ D E +G+ E +
Sbjct: 451 DEGDEGDEGDEGEDEGEDEDDEEDEGEDEGDEGDE----GEDEGDEGDEGEDEGDEGDEG 506
Query: 571 NPEKNSGQEGTQESGSSSNTFDNKDAASNKVQLTTTSDTSSEQKKDESSSAESKSESSQN 630
E + G EG E G + D D ++ + ++ +DE E + + ++
Sbjct: 507 KDEGDEGDEGKDE-GDEGDEGDEGDEGEDE------WEDEGDEGEDEGDEGEDEGDEGED 559
Query: 631 DNANSGQSNTTSDESANDNKDSSQVTTSSENSAEGNSNTENNSDENQNDSKNNENTNDSG 690
+ + G E D + E EG + DE +++ + D G
Sbjct: 560 EGEDEGDEGEDEGEDEGDEGEDEGEDEGDEGEDEGEDEGDEGEDEGEDEGDEGDEGEDEG 619
Query: 691 NTSNDANVNENQNENAAQTKTSENEGDAQNESVESKKENNESAHKDVDNNSNSNDQGSSD 750
+ D +E ++E + + +EG+ + + E + + E + D + D+G +
Sbjct: 620 DEGEDEG-DEGEDE-GDEGEDEGDEGEDEGDEGEDEGDEGEDEGDEGDEGEDEGDEGEDE 677
Query: 751 TSVTQD-----DKESRVDLGTLPESNGESHHND 778
+D D+ D G E GE D
Sbjct: 678 GDEGEDEGDEGDEGDEGDEGDEGEDEGEDEGED 710
Score = 76.3 bits (186), Expect = 3e-13
Identities = 69/364 (18%), Positives = 129/364 (34%), Gaps = 49/364 (13%)
Query: 415 TEEQFDKKEKNEFELESQKNSNETTESTDSTITQNSQGNESEKDQAQTENDTPKGSASES 474
++++ D ++ N L+ + S + + +T + Q NE E + ++D
Sbjct: 346 SDDEVDSEDGNLCVLDDESESVNSV-ALRQVLTVDKQANEKEYKKIIDKSD------DRD 398
Query: 475 DEQKQEQEQNNTTKDDVQTTDTSSQNGNDTTEKQNETSEDANSKKEDSSALNTTPNNEDS 534
D K E E N + D E + E ED +KE+ + + ED
Sbjct: 399 DRDKDEYELEN------------EEYNRDEEEDEGEDEEDEKDEKEEGE--DEGDDGEDE 444
Query: 535 KSGVAGDQADSTTTTSSSETQDGNTNHGEYKDTTNENPEKNSGQEGTQESGSSSNTFDNK 594
D+ D E +G+ E +D E+ E++ G++ E + D
Sbjct: 445 GEDEGEDEGD--------EGDEGDEGEDEGED---EDDEEDEGEDEGDEGDEGEDEGDEG 493
Query: 595 DAASNKVQLTTTSDTSSEQKKDESSSAESKSESSQNDNANSGQSNTTSDESANDNKDSSQ 654
D ++ D E K + E K E + D + G E D +
Sbjct: 494 DEGEDE------GDEGDEGKDEGDEGDEGKDEGDEGDEGDEGDEGEDEWEDEGDEGE--- 544
Query: 655 VTTSSENSAEGNSNTENNSDENQNDSKNNENTNDSGNTSNDANVNENQNENAAQTKTSEN 714
+ EG + DE +++ E D G D +E ++E E+
Sbjct: 545 -----DEGDEGEDEGDEGEDEGEDEGDEGE---DEGEDEGDEGEDEGEDEGDEGEDEGED 596
Query: 715 EGDAQNESVESKKENNESAHKDVDNNSNSNDQGSSDTSVTQDDKESRVDLGTLPESNGES 774
EGD + E + + + + D + D+G + +D+ + D G E G+
Sbjct: 597 EGDEGEDEGEDEGDEGDEGEDEGDEGEDEGDEGEDEGDEGEDEGDEGEDEGDEGEDEGDE 656
Query: 775 HHND 778
++
Sbjct: 657 GEDE 660
Score = 74.3 bits (181), Expect = 1e-12
Identities = 64/348 (18%), Positives = 122/348 (34%), Gaps = 26/348 (7%)
Query: 443 DSTITQNSQGNESEKDQAQT-----ENDTPKGSASESDEQKQEQEQNNTTKDDVQTTDTS 497
D ++ S+ + ++D+ + E D+ G+ D++ + N+ V T D
Sbjct: 324 DHKLSPVSEYEDFDEDEVELCISDDEVDSEDGNLCVLDDESESV--NSVALRQVLTVD-- 379
Query: 498 SQNGNDTTEKQNETSEDANSKKEDSSALNTTPNNEDSKSGVAGDQADSTTTTSSSETQ-D 556
Q +K + S+D + + +D L N D + D+ D E + D
Sbjct: 380 KQANEKEYKKIIDKSDDRDDRDKDEYELENEEYNRDEEEDEGEDEEDEKDEKEEGEDEGD 439
Query: 557 GNTNHGEYKDTTNENPEKNSGQEGTQESGSSSNTFD-----------NKDAASNKVQLTT 605
+ GE + +E E + G EG E + D +D +
Sbjct: 440 DGEDEGE-DEGEDEGDEGDEGDEGEDEGEDEDDEEDEGEDEGDEGDEGEDEGDEGDEGED 498
Query: 606 TSDTSSEQKKDESSSAESKSESSQNDNANSGQSNTTSDESANDNKDSSQVTTSSENSAEG 665
D E K + E K E + D + G E D + E EG
Sbjct: 499 EGDEGDEGKDEGDEGDEGKDEGDEGDEGDEGDEGEDEWEDEGDEGEDE----GDEGEDEG 554
Query: 666 NSNTENNSDENQNDSKNNENTNDSGNTSNDANVNENQNENAAQTKTSENEGDAQNESVES 725
+ + DE E+ D G + +E ++E + E+EG+ + + +
Sbjct: 555 DEGEDEGEDEGDEGEDEGEDEGDEGEDEGEDEGDEGEDEGEDEGDEGEDEGEDEGDEGDE 614
Query: 726 KKENNESAHKDVDNNSNSNDQGSSDTSVTQDDKESRVDLGTLPESNGE 773
++ + + D + D+G + +D+ + D G E G+
Sbjct: 615 GEDEGDEGEDEGDEGEDEGDEGEDEGDEGEDEGDEGEDEGDEGEDEGD 662
>MDN1_HUMAN (Q9NU22) Midasin (MIDAS-containing protein)
Length = 5596
Score = 124 bits (310), Expect = 1e-27
Identities = 129/579 (22%), Positives = 255/579 (43%), Gaps = 71/579 (12%)
Query: 62 GRKDLKPRV-EETSVIDARHKEDEEEADELDNKHDEQTKLDDVNGVEDNSEHKEDSVEQE 120
G KD+ ++ E V D K E++ ++ D+K D + + + + ED D +E
Sbjct: 4685 GMKDVSDQIGNEEQVEDTFQKGQEKDKEDPDSKSDIKGEDNAIEMSEDFDGKMHDGELEE 4744
Query: 121 SEESSQNAKTDLEGEQHTEKVDEENDNAENKENESV------EKENEEIKKEVEDTETGE 174
EE + K+D EG + + + N +K +E + E++ EE + E+T G
Sbjct: 4745 QEEDDE--KSDSEGGDLDKHMGDLNGEEADKLDERLWGDDDEEEDEEEEDNKTEETGPGM 4802
Query: 175 SIEEKSHLENEESKETGEISEEKSHLENEESKETGESSEEKSHLENEESKETGESSEEKS 234
E+ + +++ ++G +++KS + +E KE E+ ++ E++ +++ E +++
Sbjct: 4803 DEEDSELVAKDDNLDSGNSNKDKSQQDKKEEKEEAEA-DDGGQGEDKINEQIDERDYDEN 4861
Query: 235 HLENEENKDEEKSKQENEEIKDGEKIQQENEENKDEEKSQQENEENKDEEKSQQENE-LK 293
++ E+ + E ++ D + E++ ++ +++ EEN E K + E +
Sbjct: 4862 EVDPYHGNQEKVPEPEALDLPDDLNLDSEDKNGGEDTDNEEGEEENPLEIKEKPEEAGHE 4921
Query: 294 KNEGGEKETGEITEEKSKQENEETSETNSKDKENEESNQNGSDAKE----QVGENHEQDS 349
E GE ET + E +S QE EE + K E EE G+D ++ Q E H ++
Sbjct: 4922 AEERGETETDQ-NESQSPQEPEEGPSEDDK-AEGEEEMDTGADDQDGDAAQHPEEHSEEQ 4979
Query: 350 KQGTEETN---GTEGGE--------KEEHDKIKEDTSSDNQVQD----------GEKNNE 388
+Q EE + EGGE + + ++ +ED+ ++ QV + G+ E
Sbjct: 4980 QQSVEEKDKEADEEGGENGPADQGFQPQEEEEREDSDTEEQVPEALERKEHASCGQTGVE 5039
Query: 389 AREENYSGDNASSAVVDNKSQESSNKTEEQFDKKEKNE----FELESQKNSNETTES--- 441
+ + + A +A + +E ++ E +E +L SQK++ + T+S
Sbjct: 5040 NMQNTQAMELAGAAPEKEQGKEEHGSGAADANQAEGHESNFIAQLASQKHTRKNTQSFKR 5099
Query: 442 -TDSTITQNSQGNESEK-----DQAQTENDTPKGSASESDEQKQEQEQNNTTKD-----D 490
+ S G+ +E+ T++ +G A + Q ++ + K D
Sbjct: 5100 KPGQADNERSMGDHNERVHKRLRTVDTDSHAEQGPAQQPQAQVEDADAFEHIKQGSDAYD 5159
Query: 491 VQTTDTSSQ--------NGNDTTEKQ-NETSEDANSKKEDSSALNTTPNNEDSKSGVAG- 540
QT D +S+ +G D E++ +T D ++E +A E+ KSG
Sbjct: 5160 AQTYDVASKEQQQSAKDSGKDQEEEEIEDTLMDTEEQEEFKAADVEQLKPEEIKSGTTAP 5219
Query: 541 ----DQADSTTTTSSSETQDGNTNHGEYKDTTNENPEKN 575
+ T + E QD T+ +K+T NE PE++
Sbjct: 5220 LGFDEMEVEIQTVKTEEDQDPRTDKA-HKETENEKPERS 5257
Score = 104 bits (259), Expect = 1e-21
Identities = 114/634 (17%), Positives = 249/634 (38%), Gaps = 50/634 (7%)
Query: 131 DLEGEQHTEKVDEENDNAENKENESVEKENEEIKKEVEDTETGESIEEKSHLENEESKET 190
D GE TE D E E E ++ +++I E + +T + +EK + E+
Sbjct: 4663 DSAGEGATEFHDYEGGGIG--EGEGMKDVSDQIGNEEQVEDTFQKGQEK---DKEDPDSK 4717
Query: 191 GEISEEKSHLENEESKETGESSEEKSHLENEESKETGESSEEKSHLENEENKDEEKSKQE 250
+I E + +E E + E E ++ K E + H+ + N +E E
Sbjct: 4718 SDIKGEDNAIEMSEDFDGKMHDGELEEQEEDDEKSDSEGGDLDKHM-GDLNGEEADKLDE 4776
Query: 251 NEEIKDGEKIQQENEENKDEEKSQQENEENKDEEKSQQENELKKNEGGEKETGEITEEKS 310
D E+ +E E+NK EE +EE D E +++ L ++G ++KS
Sbjct: 4777 RLWGDDDEEEDEEEEDNKTEETGPGMDEE--DSELVAKDDNL--------DSGNSNKDKS 4826
Query: 311 KQENEETSETNSKDKENEESNQNGSDAKEQVGENHEQDSKQGTEETNGTEGGEKEEHDKI 370
+Q+ +E E + E ++ Q EQ+ E ++ E + G +++ +
Sbjct: 4827 QQDKKEEKE----EAEADDGGQGEDKINEQIDERDYDEN-----EVDPYHGNQEKVPEPE 4877
Query: 371 KEDTSSDNQVQDGEKNNEAREENYSGDNASSAVVDNKSQESSNKTEEQFDKKEKNEFELE 430
D D + +KN +N G+ + + K +E+ ++ EE+ E E
Sbjct: 4878 ALDLPDDLNLDSEDKNGGEDTDNEEGEEENPLEIKEKPEEAGHEAEER--------GETE 4929
Query: 431 SQKNSNETTESTDSTITQNSQGNESEKDQAQTENDTPKGSASESDEQKQEQEQNNTTKDD 490
+ +N +++ + + +++ + E + T D G A++ E+ E++Q + + D
Sbjct: 4930 TDQNESQSPQEPEEGPSEDDKAEGEE--EMDTGADDQDGDAAQHPEEHSEEQQQSVEEKD 4987
Query: 491 VQTTDTSSQNG---NDTTEKQNETSEDANSKKEDSSALNTTPNNEDSKSGVAGDQADSTT 547
+ + +NG ++ E ED++++++ AL + ++GV Q
Sbjct: 4988 KEADEEGGENGPADQGFQPQEEEEREDSDTEEQVPEALERKEHASCGQTGVENMQNTQAM 5047
Query: 548 TTSSS--ETQDGNTNHGEYKDTTN--ENPEKNSGQEGTQESGSSSNTFDNKDAASNKVQL 603
+ + E + G HG N E E N + + + NT K
Sbjct: 5048 ELAGAAPEKEQGKEEHGSGAADANQAEGHESNFIAQLASQKHTRKNTQSFKRKPGQADNE 5107
Query: 604 TTTSDTSSE-QKKDESSSAESKSESSQNDNANSGQSNTTSDESANDNKDSSQVTT----S 658
+ D + K+ + +S +E + + + E D+ T S
Sbjct: 5108 RSMGDHNERVHKRLRTVDTDSHAEQGPAQQPQAQVEDADAFEHIKQGSDAYDAQTYDVAS 5167
Query: 659 SENSAEGNSNTENNSDENQNDSKNNENTNDSGNTSNDANVNENQNENAAQTKTSENEGDA 718
E + ++ +E D+ + + ++ + + ++ +E +
Sbjct: 5168 KEQQQSAKDSGKDQEEEEIEDTLMDTEEQEEFKAADVEQLKPEEIKSGTTAPLGFDEMEV 5227
Query: 719 QNESVESKKENN---ESAHKDVDNNSNSNDQGSS 749
+ ++V+++++ + + AHK+ +N + S+
Sbjct: 5228 EIQTVKTEEDQDPRTDKAHKETENEKPERSREST 5261
Score = 88.6 bits (218), Expect = 6e-17
Identities = 105/455 (23%), Positives = 197/455 (43%), Gaps = 74/455 (16%)
Query: 54 TGNEVVKLGRKDLKPRVEETSVIDARHKEDEEEADELDNKHDEQTKLDDVNGVEDNSEHK 113
+GN ++D K EE D ED+ +++D + ++ ++D +G ++
Sbjct: 4818 SGNSNKDKSQQDKKEEKEEAEADDGGQGEDKIN-EQIDERDYDENEVDPYHGNQEKVPEP 4876
Query: 114 E-----DSVEQESEESSQNAKTDLEG--EQHTEKVDEENDNAENKENESVEKENEEIKKE 166
E D + +SE+ + TD E E++ ++ E+ + A ++ E E E ++ + +
Sbjct: 4877 EALDLPDDLNLDSEDKNGGEDTDNEEGEEENPLEIKEKPEEAGHEAEERGETETDQNESQ 4936
Query: 167 V-EDTETGESIEEKSHLENEESKETGEISEEKSHLEN--EESKETGESSEEKSHLENEES 223
++ E G S ++K+ E EE +TG ++ ++ E S+E +S EEK +EE
Sbjct: 4937 SPQEPEEGPSEDDKA--EGEEEMDTGADDQDGDAAQHPEEHSEEQQQSVEEKDKEADEEG 4994
Query: 224 KETGESSEEKSHLENEENKDEEKSKQENE--EIKDGEKIQQENEENKDEEKSQQ------ 275
E G + + E EE +D + +Q E E K+ Q EN ++ +
Sbjct: 4995 GENGPADQGFQPQEEEEREDSDTEEQVPEALERKEHASCGQTGVENMQNTQAMELAGAAP 5054
Query: 276 ENEENKDEEKS--------------------QQENELKKNEGGEKETGEITEEKSKQENE 315
E E+ K+E S Q++ K + +++ G+ E+S ++
Sbjct: 5055 EKEQGKEEHGSGAADANQAEGHESNFIAQLASQKHTRKNTQSFKRKPGQADNERSMGDHN 5114
Query: 316 E-------TSETNS--------------KDKENEESNQNGSDAKEQVGENHEQDSKQGTE 354
E T +T+S +D + E + GSDA + + ++ SK+ +
Sbjct: 5115 ERVHKRLRTVDTDSHAEQGPAQQPQAQVEDADAFEHIKQGSDAYD--AQTYDVASKE--Q 5170
Query: 355 ETNGTEGGEKEEHDKIKEDTSSDNQVQDGEKNNEAR----EENYSGDNASSAVVDNKSQE 410
+ + + G+ +E ++I EDT D + Q+ K + EE SG A + + +
Sbjct: 5171 QQSAKDSGKDQEEEEI-EDTLMDTEEQEEFKAADVEQLKPEEIKSGTTAPLGFDEMEVEI 5229
Query: 411 SSNKTEEQFD---KKEKNEFELESQKNSNETTEST 442
+ KTEE D K E E E + S E+T T
Sbjct: 5230 QTVKTEEDQDPRTDKAHKETENEKPERSRESTIHT 5264
Score = 74.3 bits (181), Expect = 1e-12
Identities = 84/459 (18%), Positives = 176/459 (38%), Gaps = 67/459 (14%)
Query: 346 EQDSKQGTEETNGTEGG---EKEEHDKIKEDTSSDNQVQDGEKNNEAREENYSGDNASSA 402
E + +G E + EGG E E + + ++ QV+D + + +++ D+ S
Sbjct: 4662 EDSAGEGATEFHDYEGGGIGEGEGMKDVSDQIGNEEQVEDTFQKGQEKDKE-DPDSKS-- 4718
Query: 403 VVDNKSQESSNKTEEQFDKKEKNEFELESQKNSNETTESTDSTITQNS---QGNESEKDQ 459
D K ++++ + E FD K ++ ELE Q+ +E ++S + ++ G E++K
Sbjct: 4719 --DIKGEDNAIEMSEDFDGK-MHDGELEEQEEDDEKSDSEGGDLDKHMGDLNGEEADKLD 4775
Query: 460 AQTENDTPKGSASESDEQKQEQEQNNTTKDDVQTTDTSSQNGNDTTEKQNETSEDANSKK 519
+ D DE++ E+E++N T++ D D+ + + D+ +
Sbjct: 4776 ERLWGD--------DDEEEDEEEEDNKTEETGPGMDEE-----DSELVAKDDNLDSGNSN 4822
Query: 520 EDSSALNTTPNNEDSKSGVAGDQADSTTTTSSSETQDGNT---NHGEYK----------- 565
+D S + E++++ G D D N HG +
Sbjct: 4823 KDKSQQDKKEEKEEAEADDGGQGEDKINEQIDERDYDENEVDPYHGNQEKVPEPEALDLP 4882
Query: 566 -DTTNENPEKNSGQEGTQESGSSSNTFDNKDAASNKVQLTTTSDTSSEQKKDESSSAESK 624
D ++ +KN G++ E G N + K E+ ++ AE +
Sbjct: 4883 DDLNLDSEDKNGGEDTDNEEGEEENPLEIK-----------------EKPEEAGHEAEER 4925
Query: 625 SESSQNDNANSGQSNTTSDESANDNKDSSQVTTSSENSAEGNS--NTENNSDENQN--DS 680
E+ + N + S +D + + + + +G++ + E +S+E Q +
Sbjct: 4926 GETETDQNESQSPQEPEEGPSEDDKAEGEEEMDTGADDQDGDAAQHPEEHSEEQQQSVEE 4985
Query: 681 KNNENTNDSG-NTSNDANVNENQNENAAQTKTSENEGDAQNESVESKKENNESAHKDVDN 739
K+ E + G N D + E + T E +A +KE+ V+N
Sbjct: 4986 KDKEADEEGGENGPADQGFQPQEEEEREDSDTEEQVPEAL-----ERKEHASCGQTGVEN 5040
Query: 740 NSNSNDQGSSDTSVTQDDKESRVDLGTLPESNGESHHND 778
N+ + + ++ + G + E H ++
Sbjct: 5041 MQNTQAMELAGAAPEKEQGKEEHGSGAADANQAEGHESN 5079
Score = 54.7 bits (130), Expect = 9e-07
Identities = 60/315 (19%), Positives = 128/315 (40%), Gaps = 60/315 (19%)
Query: 62 GRKDLKPRVEETSVIDARHKED--EEEADELDNKHDEQTKLDDVNGVEDNSEHKEDSVEQ 119
G +++ ++ A+H E+ EE+ ++ K E + NG D ++ E+
Sbjct: 4953 GEEEMDTGADDQDGDAAQHPEEHSEEQQQSVEEKDKEADEEGGENGPADQGFQPQEEEER 5012
Query: 120 ESEESSQNAKTDLEGEQHTEKVDEENDNAENKENESVEKENEEIKKEVEDTETGESIEEK 179
E ++ + LE ++H +N +N +++E +KE E G +
Sbjct: 5013 EDSDTEEQVPEALERKEHASCGQTGVENMQN--TQAMELAGAAPEKEQGKEEHGSGAADA 5070
Query: 180 SHLENEESKETGEISEEKSHLENEES--KETGESSEEKSH-------------LENEESK 224
+ E ES +++ +K +N +S ++ G++ E+S ++ +
Sbjct: 5071 NQAEGHESNFIAQLASQKHTRKNTQSFKRKPGQADNERSMGDHNERVHKRLRTVDTDSHA 5130
Query: 225 ETGESSEEKSHLENEE--------------------NKDEEKSK------QENEEIKDGE 258
E G + + ++ +E+ + +K++++S QE EEI+D
Sbjct: 5131 EQGPAQQPQAQVEDADAFEHIKQGSDAYDAQTYDVASKEQQQSAKDSGKDQEEEEIEDTL 5190
Query: 259 KIQQENEENKDEEKSQQENEENK---------DEEKSQ------QENELKKNEGGEKETG 303
+E EE K + Q + EE K DE + + +E++ + + KET
Sbjct: 5191 MDTEEQEEFKAADVEQLKPEEIKSGTTAPLGFDEMEVEIQTVKTEEDQDPRTDKAHKETE 5250
Query: 304 EITEEKSKQENEETS 318
E+S++ T+
Sbjct: 5251 NEKPERSRESTIHTA 5265
>FUTS_DROME (Q9W596) Microtubule-associated protein futsch
Length = 5412
Score = 124 bits (310), Expect = 1e-27
Identities = 164/800 (20%), Positives = 336/800 (41%), Gaps = 94/800 (11%)
Query: 41 SREQKASYGASTKTGN---EVVKLGRKDLKPRVEETSVIDAR-------HKEDEEEADEL 90
S+EQ+ +K G+ E L KD + +E S ++ KE A
Sbjct: 3275 SKEQRPESLPQSKAGSIKDEKSPLASKDEAEKSKEESRRESVAEQFPLVSKEVSRPASVA 3334
Query: 91 DNKHDEQTKLDDVNGVEDNSEHKEDSVEQESEESSQNAKTDLEGEQHTEKVDEENDNAEN 150
++ DE K + + + + SV ++ ++ +K + E EK + A
Sbjct: 3335 ESVKDEAEKSKEESPLMSKEASRPASVAGSVKDEAEKSKEESRRESVAEKSPLPSKEASR 3394
Query: 151 KEN--ESVEKENEEIKKEVEDTETGESIEEKSHLENEESKETGEISEE-KSHLENEESKE 207
+ ESV+ E ++ K+E ES EKS L ++E+ ++E K E + +
Sbjct: 3395 PASVAESVKDEADKSKEE----SRRESGAEKSPLASKEASRPASVAESIKDEAEKSKEES 3450
Query: 208 TGESSEEKSHLENEES----------KETGESSEEKSHLENEENKDEEKSKQENEEIKDG 257
ES EKS L ++E+ K+ E S+E+S ++ K SK+ +
Sbjct: 3451 RRESVAEKSPLPSKEASRPTSVAESVKDEAEKSKEESRRDSVAEKSPLASKEASRPASVA 3510
Query: 258 EKIQQENEENKDEEKSQQ----------------------ENEENKDEEKSQQENELKKN 295
E +Q E E++K+E + + ++E K +E+S++E+ +K+
Sbjct: 3511 ESVQDEAEKSKEESRRESVAEKSPLASKEASRPASVAESIKDEAEKSKEESRRESVAEKS 3570
Query: 296 EGGEKETGEITE--EKSKQENEETSETNSKDKENEESNQNGSDAKE--QVGENHEQDSKQ 351
KE T E K E E++ E +S+D E+S +A V E+ + ++++
Sbjct: 3571 PLASKEASRPTSVAESVKDEAEKSKEESSRDSVAEKSPLASKEASRPASVAESVQDEAEK 3630
Query: 352 GTEETNGTEGGEKE---EHDKIKEDTSSDNQVQDGEKNNEAREENYSGDNASSAVVDNKS 408
EE+ EK + + + +++ D EK+ E + + A +
Sbjct: 3631 SKEESRRESVAEKSPLASKEASRPASVAESVKDDAEKSKEESRRESVAEKSPLASKEASR 3690
Query: 409 QESSNKTEEQFDKKEKNEFELES--QKNSNETTESTDSTITQNSQGNESEKDQAQTEND- 465
S ++ + +K K E ES +K+ + E++ T S +E+EK + ++ +
Sbjct: 3691 PASVAESVKDEAEKSKEESRRESVAEKSPLPSKEASRPTSVAESVKDEAEKSKEESRRES 3750
Query: 466 ------------TPKGSASESDEQKQEQEQNNTTKDDV-QTTDTSSQNGNDTTEKQNETS 512
+ S +ES + + E+ + + ++ V + + +S+ +
Sbjct: 3751 VAEKSSLASKKASRPASVAESVKDEAEKSKEESRRESVAEKSPLASKEASRPASVAESVK 3810
Query: 513 EDANSKKEDSSALNTTPNNEDSKSGVAGDQADSTTTTSSSETQDGNTNHGEYKDTTNENP 572
++A KE+S + KS + +A T+ + S + + + E + +
Sbjct: 3811 DEAEKSKEESRRESVA-----EKSPLPSKEASRPTSVAESVKDEADKSKEESRRESGAEK 3865
Query: 573 EKNSGQEGTQESGSSSNTFDNKDAA---SNKVQLTTTSDTSSEQKKDESSSAESKSESSQ 629
+ E ++ + + + D + + S + +T S S++ +S AES + ++
Sbjct: 3866 SPLASMEASRPTSVAESVKDETEKSKEESRRESVTEKSPLPSKEASRPTSVAESVKDEAE 3925
Query: 630 NDNANSGQSNTTSDESANDNKDSSQ---VTTSSENSAEG---NSNTENNSDENQNDS-KN 682
S + + +++S +K+SS+ V S ++ AEG S E+ + + +S K
Sbjct: 3926 KSKEES-RRESVAEKSPLASKESSRPASVAESIKDEAEGTKQESRRESMPESGKAESIKG 3984
Query: 683 NENTNDSGNTSNDANVNENQNENAAQTKTSENEGDAQNES-VESKKENNESAHKDVDNNS 741
++++ S TS +V E + + +T + EG A ++S V S+ E+ + KD +
Sbjct: 3985 DQSSLASKETSRPDSVVE-----SVKDETEKPEGSAIDKSQVASRPESVAVSAKDEKSPL 4039
Query: 742 NSNDQGSSDTSVTQDDKESR 761
+S + +D S + SR
Sbjct: 4040 HSRPESVADKSPDASKEASR 4059
Score = 112 bits (280), Expect = 4e-24
Identities = 143/730 (19%), Positives = 284/730 (38%), Gaps = 61/730 (8%)
Query: 69 RVEETSVIDARHKEDEEEADELDNKHDEQTKLDDVNGVEDNSEHKEDSVEQESEESSQNA 128
R T ++ H ED +E ++K + L D + V S +E E S++SSQ
Sbjct: 1810 RESSTEIVLPCHAEDSKEPSRPESKVE---CLKDESEVLKGSTRRESVAE--SDKSSQPF 1864
Query: 129 KTDLEGEQHTEKVDEENDNAENKENESVE------KENEEIKKEVEDTETG-ESIEEKSH 181
K E + +E+ + E ESV+ +E E + G + ++E S
Sbjct: 1865 KETSRPESAVGSMKDESMSKEPSRRESVKDGAAQSRETSRPASVAESAKDGADDLKELSR 1924
Query: 182 LENE-ESKETGEISEEKSHLENEESKETGESSEEKSHLENEESKETGESSEEKSHLENEE 240
E+ +SKE G I +EKS L +EE+ +E K+ E S+E+S E+
Sbjct: 1925 PESTTQSKEAGSIKDEKSPLASEEASRPASVAESV--------KDEAEKSKEESRRESVA 1976
Query: 241 NKDEEKSKQENEEIKDGEKIQQENEENKDEEK-----------SQQENEENKDEEKSQQE 289
K SK+ + E I+ E E++K+E + S++ + E + E
Sbjct: 1977 EKSPLPSKEASRPASVAESIKDEAEKSKEESRRESVAEKSPLPSKEASRPASVAESIKDE 2036
Query: 290 NELKKNEGGEKETGEITEEKSKQENEETSETNSKDKENEESNQNGSDAKEQVGENHEQDS 349
E K E + E + SK+ + S S E E+S + +E V E S
Sbjct: 2037 AEKSKEESRRESVAEKSPLPSKEASRPASVAESIKDEAEKSKE--ESRRESVAEKSPLPS 2094
Query: 350 KQGTEETNGTEG----GEKEEHDKIKEDTSSDNQVQDGEKNNEAREENYSGDNASSAVVD 405
K+ + + E EK + + +E + + + E + A D A + +
Sbjct: 2095 KEASRPASVAESIKDEAEKSKEESRRESVAEKSPLPSKEASRPASVAESIKDEAEKSKEE 2154
Query: 406 NKSQESSNKTEEQFDKKEKNEFELESQKNSNETT--ESTDSTITQNSQGNESEKDQAQTE 463
++ + + K+ + + ES K+ E + ES ++ + S E + +
Sbjct: 2155 SRRESVAEKSPLPSKEASRPASVAESIKDEAEKSKEESRRESVAEKSPLPSKEASRPASV 2214
Query: 464 NDTPKGSASESDEQKQEQ---EQNNTTKDDVQTTDTSSQNGNDTTEKQNETSEDANSKKE 520
++ K A +S E+ + + E++ + + +++ D EK E S++E
Sbjct: 2215 AESIKDEAEKSKEETRRESVAEKSPLPSKEASRPASVAESIKDEAEKSKE-----ESRRE 2269
Query: 521 DSSALNTTPNNEDSK-SGVAGDQADSTTTTSSSETQDGNTNHGEYKDTT-NENPEKN-SG 577
++ + P+ E S+ + VA D + ++ G+ + +++P K S
Sbjct: 2270 SAAEKSPLPSKEASRPASVAESVKDEADKSKEESRRESMAESGKAQSIKGDQSPLKEVSR 2329
Query: 578 QEGTQESGSSSNTFDNKDAASNKVQLTTTSDTSSEQKKDESSSAESKSESSQNDNANSGQ 637
E ES + + V + T+D++ +D+ S ESK S +S +
Sbjct: 2330 PESVAESVKDDPVKSKEPSRRESVAGSVTADSA----RDDQSPLESKGASRPESVVDSVK 2385
Query: 638 SNTTSDESANDNKDSSQVTTSSENSAEGN------SNTENNSDENQNDSKNNENTNDSGN 691
ES ++K S + +++ S TE ++ K ++ + +
Sbjct: 2386 DEAEKQESRRESKTESVIPPKAKDDKSPKEVLQPVSMTETIREDADQPMKPSQAESRRES 2445
Query: 692 TSNDANVNENQNENAAQTKTSENEGDAQNESVESKKENNESAHKDVDNNSNSNDQGSSDT 751
+ + ++E + + + ES++ + + D + + +
Sbjct: 2446 IAESIKASSPRDEKSPLASKEASRPGSVAESIKYDLDKPQIIKDDKSTEHSRRESLEDKS 2505
Query: 752 SVTQDDKESR 761
+VT + SR
Sbjct: 2506 AVTSEKSVSR 2515
Score = 112 bits (279), Expect = 5e-24
Identities = 148/730 (20%), Positives = 306/730 (41%), Gaps = 81/730 (11%)
Query: 84 EEEADELDNKHDEQTKLDDVNGVEDNSEHKEDSVEQESEESSQNAKTDLEGEQHTEKVDE 143
++E D+ +++ + K++ V S+ K S + + +E S A E + V+
Sbjct: 2899 KDEHDKAESRRESIAKVESVIDEAGKSDSKSSSQDSQKDEKSTLASK--EASRRESVVES 2956
Query: 144 ENDNAENKEN--ESVEKENEEIKKEVE------DTETGESIEEKSHLENEESKETGEISE 195
D+AE E+ ESV E + +E + DT S+ E E+E+S++ E
Sbjct: 2957 SKDDAEKSESRPESVIASGEPVPRESKSPLDSKDTSRPGSMVESVTAEDEKSEQQSR-RE 3015
Query: 196 EKSHLENEESKETGESSE-------EKSHLENEESKETGESSEEKSHLENEENKDE---- 244
+ ++K+ G+S E ++ +++E +E+ S SH DE
Sbjct: 3016 SVAESVKADTKKDGKSQEASRPSSVDELLKDDDEKQESRRQSITGSHKAMSTMGDESPMD 3075
Query: 245 --EKSKQENEEIKDGEKIQQENEENKDEEK---SQQEN--EENKDEEKSQQENELKKNEG 297
+KSK+ + E I+ EN KDEE S++++ E K + +++ L E
Sbjct: 3076 KADKSKEPSRPESVAESIKHEN--TKDEESPLGSRRDSVAESIKSDITKGEKSPLPSKEV 3133
Query: 298 GEKET--GEITEEKSKQENEETSET----NSKDKENEESNQNGSDAKEQVGENHEQDSKQ 351
E+ G I +EK++ E +E+ +SKD + ++ S + +G ++ K
Sbjct: 3134 SRPESVVGSIKDEKAESRRESVAESVKPESSKDATSAPPSKEHSRPESVLGSLKDEGDKT 3193
Query: 352 GTEETNGTEGGEKEEHDKIKEDTSSDNQVQDGEKNNEA-REENYSGDNASSAVVDNKSQE 410
+ + + + E+ + ++ S + K+ A +E ++ + +V D KS
Sbjct: 3194 TSRRVSVADSIKDEKSLLVSQEASRPESEAESLKDAAAPSQETSRPESVTESVKDGKSPV 3253
Query: 411 SSNKTEEQFDKKEKNEFELESQKNSNETTESTDSTITQNSQGNESEKDQAQTENDTPKGS 470
+S + E ++ +++E+ E ++ Q+ G S KD+ +P S
Sbjct: 3254 ASKEASRPASVAE------NAKDSADESKEQRPESLPQSKAG--SIKDE-----KSPLAS 3300
Query: 471 ASESDEQKQEQEQNNTTKDDVQTTDTSSQNGNDTTEKQNETSEDANSKKEDSSALNTTPN 530
E+++ K+E + + + S+ + ++A KE+S ++ +
Sbjct: 3301 KDEAEKSKEESRRESV----AEQFPLVSKEVSRPASVAESVKDEAEKSKEESPLMSKEAS 3356
Query: 531 NEDSKSGVAGDQADSTTTTSSSET--------QDGNTNHGEYKDTTNENPEKNSGQEGTQ 582
S +G D+A+ + S E+ + ++ + +K S +E +
Sbjct: 3357 RPASVAGSVKDEAEKSKEESRRESVAEKSPLPSKEASRPASVAESVKDEADK-SKEESRR 3415
Query: 583 ESGSSSNTFDNKDA---ASNKVQLTTTSDTSSEQKKDESSSAESKSES-----------S 628
ESG+ + +K+A AS + ++ S E+ + ES + +S S S
Sbjct: 3416 ESGAEKSPLASKEASRPASVAESIKDEAEKSKEESRRESVAEKSPLPSKEASRPTSVAES 3475
Query: 629 QNDNANSGQSNTTSDESANDNKDSSQVTTSSENSAEG-NSNTENNSDENQNDSKNNENTN 687
D A + + D A + +S+ + + AE E + +E++ +S ++
Sbjct: 3476 VKDEAEKSKEESRRDSVAEKSPLASKEASRPASVAESVQDEAEKSKEESRRESVAEKSPL 3535
Query: 688 DSGNTSNDANVNENQNENAAQTK-TSENEGDAQNESVESKKENN-ESAHKDVDNNSNSND 745
S S A+V E+ + A ++K S E A+ + SK+ + S + V + + +
Sbjct: 3536 ASKEASRPASVAESIKDEAEKSKEESRRESVAEKSPLASKEASRPTSVAESVKDEAEKSK 3595
Query: 746 QGSSDTSVTQ 755
+ SS SV +
Sbjct: 3596 EESSRDSVAE 3605
Score = 108 bits (270), Expect = 5e-23
Identities = 144/757 (19%), Positives = 307/757 (40%), Gaps = 77/757 (10%)
Query: 64 KDLKPRVEETSVIDARHKEDEEEADELDNKHDEQTKLDD--VNGVEDNSEHKEDSVEQES 121
+ +KP + + KE L + DE K V+ + + K V QE+
Sbjct: 3157 ESVKPESSKDATSAPPSKEHSRPESVLGSLKDEGDKTTSRRVSVADSIKDEKSLLVSQEA 3216
Query: 122 ---EESSQNAKTDLEGEQHTEKVDEENDNAENKENESVEKENEEIKKEVEDTETGESIEE 178
E +++ K Q T + + ++ ++ ++ KE E+ + +
Sbjct: 3217 SRPESEAESLKDAAAPSQETSRPESVTESVKDGKSPVASKEASRPASVAENAKDSADESK 3276
Query: 179 KSHLENEESKETGEISEEKSHLENEESKETGESSEEKSHLEN------------------ 220
+ E+ + G I +EKS L SK+ E S+E+S E+
Sbjct: 3277 EQRPESLPQSKAGSIKDEKSPLA---SKDEAEKSKEESRRESVAEQFPLVSKEVSRPASV 3333
Query: 221 -EESKETGESSEEKSHLENEEN----------KDE-EKSKQENEEIKDGEKIQQENEEN- 267
E K+ E S+E+S L ++E KDE EKSK+E+ EK ++E
Sbjct: 3334 AESVKDEAEKSKEESPLMSKEASRPASVAGSVKDEAEKSKEESRRESVAEKSPLPSKEAS 3393
Query: 268 ---------KDE-EKSQQENEENKDEEKSQQENELKKNEGGEKETGEITEEKSKQENEET 317
KDE +KS++E+ EKS ++ E+ + EKSK+E+
Sbjct: 3394 RPASVAESVKDEADKSKEESRRESGAEKSPLASKEASRPASVAESIKDEAEKSKEESRRE 3453
Query: 318 SETNSKDKENEESNQNGSDA---KEQVGENHEQDSKQGTEETNGTEGGEKEEHDKIKEDT 374
S ++E+++ S A K++ ++ E+ + E + E + E
Sbjct: 3454 SVAEKSPLPSKEASRPTSVAESVKDEAEKSKEESRRDSVAEKSPLASKEASRPASVAESV 3513
Query: 375 SSDNQVQDGEKNNE--AREENYSGDNAS--SAVVDNKSQESSNKTEEQFDKKEKNEFELE 430
+ + E E A + + AS ++V ++ E+ EE + + L
Sbjct: 3514 QDEAEKSKEESRRESVAEKSPLASKEASRPASVAESIKDEAEKSKEESRRESVAEKSPLA 3573
Query: 431 SQKNSNETT------ESTDSTITQNSQGNESEKDQAQTENDTPKGSASESDEQKQEQEQN 484
S++ S T+ + + + ++S+ + +EK ++ + S +ES + + E+ +
Sbjct: 3574 SKEASRPTSVAESVKDEAEKSKEESSRDSVAEKSPLASKEASRPASVAESVQDEAEKSKE 3633
Query: 485 NTTKDDV-QTTDTSSQNGNDTTEKQNETSEDANSKKEDSSALNTTPNNEDSKSGVAGDQA 543
+ ++ V + + +S+ + +DA KE+S + KS +A +A
Sbjct: 3634 ESRRESVAEKSPLASKEASRPASVAESVKDDAEKSKEESRRESVA-----EKSPLASKEA 3688
Query: 544 DSTTTTSSSETQDGNTNHGEYKDTTNENPEKNSGQEGTQESGSSSNTFDNKDAASNKVQL 603
+ + S + + E + + +E ++ + + + D + + + +
Sbjct: 3689 SRPASVAESVKDEAEKSKEESRRESVAEKSPLPSKEASRPTSVAESVKDEAEKSKEESRR 3748
Query: 604 TTTSDTSSEQKKDES---SSAESKSESSQNDNANSGQSNTTSDESANDNKDSSQVTTSSE 660
+ ++ SS K S S AES + ++ S + + +++S +K++S+ + +E
Sbjct: 3749 ESVAEKSSLASKKASRPASVAESVKDEAEKSKEES-RRESVAEKSPLASKEASRPASVAE 3807
Query: 661 NSAEGNSNTENNSDENQNDSKNNENTNDSGNTSNDANVNENQNENAAQTK-TSENEGDAQ 719
+ + E + +E++ +S ++ S S +V E+ + A ++K S E A+
Sbjct: 3808 SVKD---EAEKSKEESRRESVAEKSPLPSKEASRPTSVAESVKDEADKSKEESRRESGAE 3864
Query: 720 NESVESKKENN-ESAHKDVDNNSNSNDQGSSDTSVTQ 755
+ S + + S + V + + + + S SVT+
Sbjct: 3865 KSPLASMEASRPTSVAESVKDETEKSKEESRRESVTE 3901
Score = 106 bits (265), Expect = 2e-22
Identities = 127/625 (20%), Positives = 262/625 (41%), Gaps = 68/625 (10%)
Query: 78 ARHKEDEEEADELDNKHDEQTKLDDVNGVEDNSEHK-EDSVEQESEESSQNAKTDLEGEQ 136
A +DE E + +++ D + + E + +SV+ E+E+S + ++ + E+
Sbjct: 3473 AESVKDEAEKSKEESRRDSVAEKSPLASKEASRPASVAESVQDEAEKSKEESRRESVAEK 3532
Query: 137 HTEKVDEENDNAENKENESVEKENEEIKKEVEDTETGESIEEKSHLENEESKETGEISEE 196
E + A E S++ E E+ K+E ES+ EKS L ++E+ ++E
Sbjct: 3533 SPLASKEASRPASVAE--SIKDEAEKSKEE----SRRESVAEKSPLASKEASRPTSVAES 3586
Query: 197 -KSHLENEESKETGESSEEKSHLENEES----------KETGESSEEKSHLENEENKDEE 245
K E + + + +S EKS L ++E+ ++ E S+E+S E+ K
Sbjct: 3587 VKDEAEKSKEESSRDSVAEKSPLASKEASRPASVAESVQDEAEKSKEESRRESVAEKSPL 3646
Query: 246 KSKQENEEIKDGEKIQQENEENKDEEK-----------SQQENEENKDEEKSQQENELKK 294
SK+ + E ++ + E++K+E + S++ + E + E E K
Sbjct: 3647 ASKEASRPASVAESVKDDAEKSKEESRRESVAEKSPLASKEASRPASVAESVKDEAEKSK 3706
Query: 295 NEGGEKETGEITEEKSKQENEETSETNSKDKENEESNQNGSDAKEQVGENHEQDSKQGTE 354
E + E + SK+ + TS S E E+S + +E V E SK+ +
Sbjct: 3707 EESRRESVAEKSPLPSKEASRPTSVAESVKDEAEKSKE--ESRRESVAEKSSLASKKASR 3764
Query: 355 ETNGTEGGEKEEHDKIKEDTSSDNQVQDGEKNNEAREENYSGDNASSAVVDNKSQESSNK 414
+ E K+E +K KE++ ++ EK+ A +E + ++V ++ E+
Sbjct: 3765 PASVAE-SVKDEAEKSKEESRRESV---AEKSPLASKE----ASRPASVAESVKDEAEKS 3816
Query: 415 TEEQFDKKEKNEFELESQKNSNETT------ESTDSTITQNSQGNESEKDQAQTENDTPK 468
EE + + L S++ S T+ + D + ++ + + +EK + +
Sbjct: 3817 KEESRRESVAEKSPLPSKEASRPTSVAESVKDEADKSKEESRRESGAEKSPLASMEASRP 3876
Query: 469 GSASESDEQKQEQEQNNTTKDDV-QTTDTSSQNGNDTTEKQNETSEDANSKKEDS---SA 524
S +ES + + E+ + + ++ V + + S+ + T ++A KE+S S
Sbjct: 3877 TSVAESVKDETEKSKEESRRESVTEKSPLPSKEASRPTSVAESVKDEAEKSKEESRRESV 3936
Query: 525 LNTTPNNEDSKSGVAG------DQADSTTTTSSSETQDGNTNHGEYKDTTNENPEKNSGQ 578
+P S A D+A+ T S E+ + K + K + +
Sbjct: 3937 AEKSPLASKESSRPASVAESIKDEAEGTKQESRRESMPESGKAESIKGDQSSLASKETSR 3996
Query: 579 EGTQESGSSSNTFDNKDAASNKVQLTTTSDTSSEQKKDESSSAESKSESSQNDNANSGQS 638
+ T + +A +K Q+ + ++ + KDE S S+ ES
Sbjct: 3997 PDSVVESVKDETEKPEGSAIDKSQVASRPESVAVSAKDEKSPLHSRPES----------- 4045
Query: 639 NTTSDESANDNKDSSQVTTSSENSA 663
+D+S + +K++S+ + +E ++
Sbjct: 4046 --VADKSPDASKEASRSLSVAETAS 4068
Score = 105 bits (263), Expect = 4e-22
Identities = 144/728 (19%), Positives = 289/728 (38%), Gaps = 56/728 (7%)
Query: 81 KEDEEEADELDNKHDEQTKLDDVNGVEDNSEHKEDSVEQESEESSQNAKTDLEGEQHTEK 140
K++ E++ E + K + +SV+ E+E+S + + D E+
Sbjct: 3551 KDEAEKSKEESRRESVAEKSPLASKEASRPTSVAESVKDEAEKSKEESSRDSVAEKSPLA 3610
Query: 141 VDEENDNAENKENESVEKENEEIKKEVEDTETGESIEEKSHLENEESKETGEISEE-KSH 199
E + A E SV+ E E+ K+E ES+ EKS L ++E+ ++E K
Sbjct: 3611 SKEASRPASVAE--SVQDEAEKSKEE----SRRESVAEKSPLASKEASRPASVAESVKDD 3664
Query: 200 LENEESKETGESSEEKSHLENEESKE---TGESSEEKSHLENEENKDEEKSKQENEEIKD 256
E + + ES EKS L ++E+ ES ++++ EE++ E +++ K+
Sbjct: 3665 AEKSKEESRRESVAEKSPLASKEASRPASVAESVKDEAEKSKEESRRESVAEKSPLPSKE 3724
Query: 257 GEKIQQENEENKDE-EKSQQENEENKDEEKSQQENELKKNEGGEKETGEITEEKSKQENE 315
+ E KDE EKS++E+ EKS ++ E+ + EKSK+E+
Sbjct: 3725 ASRPTSVAESVKDEAEKSKEESRRESVAEKSSLASKKASRPASVAESVKDEAEKSKEESR 3784
Query: 316 ETSETNSKDKENEESNQNGSDA---KEQVGENHEQDSKQGTEETNGTEGGEKEEHDKIKE 372
S ++E+++ S A K++ ++ E+ ++ E + E + E
Sbjct: 3785 RESVAEKSPLASKEASRPASVAESVKDEAEKSKEESRRESVAEKSPLPSKEASRPTSVAE 3844
Query: 373 DTSSDNQVQDGEKNNEAREENYSGDNASSAVVDNKSQESSNKTEEQFDKKEKNEFELESQ 432
+ D K RE +S + + + +E KE++ E ++
Sbjct: 3845 SVKDE---ADKSKEESRRESGAEKSPLASMEASRPTSVAESVKDETEKSKEESRRESVTE 3901
Query: 433 KNSNETTESTDSTITQNSQGNESEKDQAQTENDT-PKGSASESDEQKQEQEQNNTTKDDV 491
K+ + E++ T S +E+EK + ++ ++ + S S E + + KD+
Sbjct: 3902 KSPLPSKEASRPTSVAESVKDEAEKSKEESRRESVAEKSPLASKESSRPASVAESIKDEA 3961
Query: 492 QTTDTSS------QNGNDTTEKQNETSEDANSKKEDSSALNTTPNNEDSKSGVAGDQADS 545
+ T S ++G + K +++S + S + + + + G A D++
Sbjct: 3962 EGTKQESRRESMPESGKAESIKGDQSSLASKETSRPDSVVESVKDETEKPEGSAIDKSQV 4021
Query: 546 TTTTSS---SETQDGNTNHGEYKDTTNENPEKN---SGQEGTQESGSSSNTFDNKDAASN 599
+ S S + + H + +++P+ + S E+ SS + A
Sbjct: 4022 ASRPESVAVSAKDEKSPLHSRPESVADKSPDASKEASRSLSVAETASSPIEEGPRSIADL 4081
Query: 600 KVQLTTTSDT-------SSEQKKDESSSAESKSESSQNDNANSGQSNTTSDESANDNKDS 652
+ L T + SS E E K+ESS S + + ++ +
Sbjct: 4082 SLPLNLTGEAKGKLPTLSSPIDVAEGDFLEVKAESSPRPAVLSKPAEFSQPDTGH----- 4136
Query: 653 SQVTTSSENSAEGNSNTENNSDENQNDSKNNENTNDSGNTSNDANVNENQNENAAQTKTS 712
T+S E + E Q+ +G T+ ++ + ++ TK S
Sbjct: 4137 ----TASTPVDEASPVLEEIEVVEQH---TTSGVGATGATAETDLLDLTETKSETVTKQS 4189
Query: 713 ENE-GDAQNESVESKKENNESAHKDVDNNSNSNDQGSSDT------SVTQDDKESRVDLG 765
E + VESK E ES+ K V+ ++ + + T +T+ E ++
Sbjct: 4190 ETTLFETLTSKVESKVEVLESSVKQVEEKVQTSVKQAETTVTDSLEQLTKKSSEQLTEIK 4249
Query: 766 TLPESNGE 773
++ ++N E
Sbjct: 4250 SVLDTNFE 4257
Score = 93.2 bits (230), Expect = 2e-18
Identities = 156/806 (19%), Positives = 308/806 (37%), Gaps = 138/806 (17%)
Query: 54 TGNEVVKLGRKDLKPRVEETSVIDARHKEDEEEADELDNKHDEQTKLDDVNGVEDNSEHK 113
T + +V D ++ + A + D E+ ELD+ +EQ + ++ V E K
Sbjct: 850 TDSSLVSTPSADEATAAKKLQDLTASQELDAEKQRELDDLKEEQEVVREIEAVFSRDEMK 909
Query: 114 EDSVEQESEESSQNAKTDLEGEQHTEKVDEENDNAENKENESVEKENEEIKKEVEDT--- 170
+ Q K +L D EN+ E +E +EKE E+++ ED+
Sbjct: 910 R--------QQHQQIKAELREMPAEGTGDGENEPDEEEEYLIIEKE--EVEQYTEDSIVE 959
Query: 171 -ETGESIEEKSHLENEESKETGEISEEKSHLENEESKETGESSEEKSHLE-----NEESK 224
E+ + EE+ +S+E+ + ++ + E E + E++E K+ LE +ES+
Sbjct: 960 QESSMTKEEEIQKHQRDSQESEKKRKKSAEEEIEAAIAKVEAAERKARLEGASARQDESE 1019
Query: 225 ETGESSEEKSHLENEE----NKDEEKSKQENEEIKDGEKIQQENEENKDEEKSQQENEEN 280
E + K E ++ KD KS+ E + K E +E EEK ++ +
Sbjct: 1020 LDVEPEQSKIKAEVQDIIATAKDIAKSRTEEQLAKPAE---EELSSPTPEEKLSKKTSDT 1076
Query: 281 KDEEKSQQENELKKN--------------EGGEKETGEITEE--------------KSKQ 312
KD++ + L N E G + E+ + K
Sbjct: 1077 KDDQIGAPVDVLPVNLQESLPEEKFSATIESGATTAPTLPEDERIPLDQIKEDLVIEEKY 1136
Query: 313 ENEETSETNSKDKENEESNQNGSD-AKEQVGENHEQDS-KQGTEETNG--TEGGEK---- 364
EET E + ++ + A + + + +D+ K E G + GE+
Sbjct: 1137 VKEETKEAEAIVVATVQTLPEAAPLAIDTILASATKDAPKDANAEALGELPDSGERVLPM 1196
Query: 365 -----EEHDKIKEDTSSDNQVQDGEKNNEAREENYSGDNASSAVVDNKSQESSNKTEEQF 419
+ + +++ + ++V D + EA Y D+ + +E S K E++
Sbjct: 1197 KMTFEAQQNLLRDVIKTPDEVADLPVHEEADLGLYEKDSQDAGAKSISHKEESAKEEKET 1256
Query: 420 DKKEKNE---------------------------------FELESQKNSNETTESTDSTI 446
D +++N+ E +K E E+T + I
Sbjct: 1257 DDEKENKVGEIELGDEPNKVDISHVLLKESVQEVAEKVVVIETTVEKKQEEIVEAT-TVI 1315
Query: 447 TQNSQGN--ESEKDQAQTENDTPKGSASESDEQK-----QEQEQNNTTKDD---VQTTDT 496
TQ +Q + E KD+ + E G +E + +K +E+E ++ T DD Q D
Sbjct: 1316 TQENQEDLMEQVKDKEEHEQKIESGIITEKEAKKSASTPEEKETSDITSDDELPAQLADP 1375
Query: 497 SSQNGNDTTEKQNETSEDANSKKEDSSALNTTPNNEDSKSGVAGDQADST--TTTSSSET 554
++ ++++ S ++ E++ + E K A ++A T + +S ET
Sbjct: 1376 TTVPPKSAKDREDTGSIESPPTIEEAIEVEVQAKQEAQKPVPAPEEAIKTEKSPLASKET 1435
Query: 555 QDGNTNHGEYKDTTNENPEKNSGQEGTQESGSSSNTFDNKDAASNKVQLTTTSDTSSEQK 614
+ G K+ T + K S ES D S
Sbjct: 1436 SRPESATGSVKEDTEQTKSKKSPVPSRPES--------------------EAKDKKSPFA 1475
Query: 615 KDESSSAESKSESSQNDNANSGQSNTTSDESANDNKDSSQVTTSSENSAEGNSNTENNSD 674
E+S ES +ES +++ +G++ + + A +KD S + + E + S E+
Sbjct: 1476 SGEASRPESVAESVKDE---AGKAESRRESIAKTHKDESSLDKAKEQESRRESLAESIKP 1532
Query: 675 ENQNDSKNNENTNDSGNTSN--DANVNENQNENAAQTKTSENEGDAQNESVESKKENNES 732
E+ D K+ + ++ + D + ++ E+ A++ +E+ D ++ + S
Sbjct: 1533 ESGIDEKSALASKEASRPESVTDKSKEPSRRESIAESLKAESTKDEKSAPPSKEASRPGS 1592
Query: 733 AHKDVDNNSNSNDQGSSDTSVTQDDK 758
+ V + + + + S S+ + K
Sbjct: 1593 VVESVKDETEKSKEPSRRESIAESAK 1618
Score = 91.3 bits (225), Expect = 9e-18
Identities = 132/626 (21%), Positives = 261/626 (41%), Gaps = 51/626 (8%)
Query: 190 TGEISEEKSHLENEESKETGESSEEKSHLENEESKETGESSEEKSHLENEENKDEEKSKQ 249
TG +E E ET E + E SK + +S ++ E K + KQ
Sbjct: 4166 TGATAETDLLDLTETKSETVTKQSETTLFETLTSKVESKVEVLESSVKQVEEKVQTSVKQ 4225
Query: 250 ENEEIKDG-EKIQQENEENKDEEKSQQENEENKDEEKSQQENELKKNEGGEKETGEITEE 308
+ D E++ +++ E E KS + EE ++ ++ K +K+ +I +
Sbjct: 4226 AETTVTDSLEQLTKKSSEQLTEIKSVLDTNF---EEVAKIVADVAKVLKSDKDITDIIPD 4282
Query: 309 KSKQENEETSETNSKDKENEESNQNGSDAKEQVGENHEQDSKQGTEETNGTEGGEKEEHD 368
+++ EE ++ + +E + + + E + + K ++ +G EE D
Sbjct: 4283 FDERQLEEKLKSTADTEEESDKSTRDEKSLEISVKVEIESEKSSPDQKSGPIS--IEEKD 4340
Query: 369 KIKEDTSSDNQVQDGEKNNEAREENYSGDNASSAVVDNKSQESSNKTEEQFDKKEKNEFE 428
KI++ S Q++ G + +R E+ + S V + SQ +++ ++ + E ++ E
Sbjct: 4341 KIEQ--SEKAQLRQGILTS-SRPESVASQPES---VPSPSQSAASHEHKEVELSESHKAE 4394
Query: 429 LESQKNS-----NETTESTDSTITQNSQGNESEKDQAQTENDTPKGSASESDEQKQEQEQ 483
S+ S +E T + SQ + E D+ TE+ + +E+ E KQ +E+
Sbjct: 4395 KSSRPESVASQVSEKDMKTSRPASSTSQFSTKEGDEETTESLLHSLTTTETVETKQMEEK 4454
Query: 484 NNTTKDDVQTTDTSSQNGNDTTEKQNE-TSEDANS--KKEDSSALNTTPNNEDSKSGVAG 540
++ T ++ + T + + E TSE +S K EDSS +S S +
Sbjct: 4455 SSFESVSTSVTKSTVLSSQSTVQLREESTSESLSSSLKVEDSS-------RRESLSSLLA 4507
Query: 541 DQADSTTTTSSSETQDGNTNHGEYKDTTNENPEKNSGQEGTQESGSSSNTFDNKDAASNK 600
++ T TS E + + E +E S Q S + + + KDA K
Sbjct: 4508 EKGGIATNTSLKEDTSASASQLEELLVQSEECSSESIVSEIQTSIAQKSNKEIKDARETK 4567
Query: 601 VQLTTTSDTSSEQKKDESSSAESKSESSQNDNANSGQSNTTSDESANDNKDSSQVTTSSE 660
V T+ TSS K D ++ +++ + +T + +SA+D + + S
Sbjct: 4568 VTSQFTTTTSSATKDDSLKETVAEFLATEKIVSAKEAFSTEATKSADDCLKKTTASAVSS 4627
Query: 661 NSAE------GNSNTENNS-----DENQNDSKNNENTNDSGNTSNDANVNENQNENAAQT 709
SA G + S E++ + E+ + + ++V E+++++ A
Sbjct: 4628 TSASQRALFVGTDESRRESLLSQASESRLTHSDPEDEEPADDVDERSSVKESRSKSIATI 4687
Query: 710 ------KTSENEGDAQNESVESKKENNESAHKDVDNNS------NSNDQGSSDTSVTQDD 757
K SE + + ++ VE + E+ E ++V + S S++Q S+ TS T
Sbjct: 4688 MMTSIYKPSE-DMEPISKLVEEEHEHVEELAQEVTSTSKTTTLLQSSEQSSTTTSSTSKT 4746
Query: 758 KESRVDLGTLPESNGESHHNDVSSAE 783
SRV+ TL + + ++ + A+
Sbjct: 4747 GASRVESITLTQMDQQTSQSQGDPAD 4772
Score = 88.2 bits (217), Expect = 8e-17
Identities = 140/744 (18%), Positives = 300/744 (39%), Gaps = 81/744 (10%)
Query: 83 DEEEADELDNKHDEQTKLDDVNGVEDNS-EHKEDSVEQESEESSQNA-KTDLEGEQHTEK 140
+E+E ++ + + +L D V S + +ED+ ES + + A + +++ +Q +K
Sbjct: 1355 EEKETSDITSDDELPAQLADPTTVPPKSAKDREDTGSIESPPTIEEAIEVEVQAKQEAQK 1414
Query: 141 --------VDEENDNAENKENESVEKENEEIKKEVEDTETGES-IEEKSHLENEESKE-- 189
+ E +KE E +K++ E T++ +S + + E ++ K
Sbjct: 1415 PVPAPEEAIKTEKSPLASKETSRPESATGSVKEDTEQTKSKKSPVPSRPESEAKDKKSPF 1474
Query: 190 -TGEISEEKSHLENEESK----ETGESSEEKSHLEN---EESKETGESSEEKSHLENEEN 241
+GE S +S E+ + + E+ S K+H + +++KE E + E+
Sbjct: 1475 ASGEASRPESVAESVKDEAGKAESRRESIAKTHKDESSLDKAKEQESRRESLAESIKPES 1534
Query: 242 KDEEKSKQENEEIKDGEKIQQENEE-NKDEEKSQQENEENKDEEKSQQENELKKNEGGEK 300
+EKS ++E E + +++E ++ E ++ E+ +EKS ++ G
Sbjct: 1535 GIDEKSALASKEASRPESVTDKSKEPSRRESIAESLKAESTKDEKSAPPSKEASRPGSVV 1594
Query: 301 ETGEITEEKSKQENEETSETNS-------KDKENEESNQNGSDAKEQVGENHEQDSKQGT 353
E+ + EKSK+ + S S ++ ES +G E +DS +
Sbjct: 1595 ESVKDETEKSKEPSRRESIAESAKPPIEFREVSRPESVIDGI-KDESAKPESRRDSPLAS 1653
Query: 354 EETNGTE------------GGEKEEHDKIKEDTSSDNQVQDGEKNNEAREENYSGDNASS 401
+E + E EK + + E +D+ EK+ ++ ++A
Sbjct: 1654 KEASRPESVLESVKDEPIKSTEKSRRESVAESFKADS--TKDEKSPLTSKDISRPESAVE 1711
Query: 402 AVVDNKSQESSNKTEEQFDKKE--KNEFELESQKNSNETTESTDSTITQNSQGNESEKDQ 459
V+D ++ E ++ + E ES+K+ + ES ++ S E EK
Sbjct: 1712 NVMDAVGSAERSQPESVTASRDVSRPESVAESEKDDTDKPESVVESVIPASDVVEIEKGA 1771
Query: 460 AQTEN-----------DTPK------GSASESDEQKQEQEQNNTTKDDVQTTDTSSQN-- 500
A E D+P G ES + + +E + D+ +
Sbjct: 1772 ADKEKGVFVSLEIGKPDSPSEVISRPGPVVESVKPESRRESSTEIVLPCHAEDSKEPSRP 1831
Query: 501 -------GNDTTEKQNETSEDANSKKEDSSALNTTPNNEDSKSGVAGDQADSTTTTSSSE 553
+++ + T ++ ++ + SS + +S G D++ S +
Sbjct: 1832 ESKVECLKDESEVLKGSTRRESVAESDKSSQPFKETSRPESAVGSMKDESMSKEPSRRES 1891
Query: 554 TQDGNTNHGEYKDTTNENPEKNSGQEGTQESGSSSNTFDNKDAASNKVQLTTTSDTSSEQ 613
+DG E + G + +E +T +K+A S K + S +SE+
Sbjct: 1892 VKDGAAQSRETSRPASVAESAKDGADDLKELSRPESTTQSKEAGSIKDE---KSPLASEE 1948
Query: 614 KKDESSSAESKSESSQNDNANSGQSNTTSDESANDNKDSSQVTTSSENSAEGNSNTENNS 673
+S AES + ++ S + + +++S +K++S+ + +E+ + E +
Sbjct: 1949 ASRPASVAESVKDEAEKSKEES-RRESVAEKSPLPSKEASRPASVAESIKD---EAEKSK 2004
Query: 674 DENQNDSKNNENTNDSGNTSNDANVNENQNENAAQTK-TSENEGDAQNESVESKKENN-E 731
+E++ +S ++ S S A+V E+ + A ++K S E A+ + SK+ +
Sbjct: 2005 EESRRESVAEKSPLPSKEASRPASVAESIKDEAEKSKEESRRESVAEKSPLPSKEASRPA 2064
Query: 732 SAHKDVDNNSNSNDQGSSDTSVTQ 755
S + + + + + + S SV +
Sbjct: 2065 SVAESIKDEAEKSKEESRRESVAE 2088
Score = 77.0 bits (188), Expect = 2e-13
Identities = 134/680 (19%), Positives = 250/680 (36%), Gaps = 74/680 (10%)
Query: 136 QHTEKVDEENDNAENKENESVEKENEEIKKEVEDTETGESIEEKSHLENEESKETGEISE 195
+H + D + A ++E S +K + +K+ ES ++ + L++ + +
Sbjct: 2644 EHISRADSPAECA-SEEIASQDKSPQVLKESSRPAWVAESKDDAAQLKSS-------VED 2695
Query: 196 EKSHLENEESKETGESSEEKSHLENEESKETGESSE-EKSHLE-NEENKDEEKSKQENEE 253
+S + + E + E S E K+ E + EK+ L E K + +
Sbjct: 2696 LRSPVASTEISRPASAGETASSPIEEAPKDFAEFEQAEKAVLPLTIELKGNLPTLSSPVD 2755
Query: 254 IKDGEKIQQENEENKDEEKSQQENEENK-DEEKSQQE--NELKKNEGG----EKETGEIT 306
+ G+ Q + S Q E +K D EK+ +E K+ G E+
Sbjct: 2756 VAHGDFPQTSTPTSSPTVASVQPAELSKVDIEKTASSPIDEAPKSLIGCPAEERPESPAE 2815
Query: 307 EEKSKQENEETSETNSKDKENEESNQNGSD------AKEQVGENHEQDSKQGTEETNGTE 360
K E+ E S+ S+ ES + S + E V E + D ++ E +
Sbjct: 2816 SAKDAAESVEKSKDASRPPSVVESTKADSTKGDISPSPESVLEGPKDDVEKSKESSRPPS 2875
Query: 361 GGEKEEHDKIKEDTSSDNQVQDGEKNNEAREENYSGDNASSAVVDNKSQESSNKTEEQFD 420
D K+ + + V+ + ++ E +V+D + S + +
Sbjct: 2876 VSASITGDSTKDVSRPASVVESVKDEHDKAESRRESIAKVESVIDEAGKSDSKSSSQDSQ 2935
Query: 421 KKEKN----------EFELESQKNSNETTESTDSTITQNSQGNESEKDQAQTENDTPK-G 469
K EK+ E +ES K+ E +ES ++ + + E DT + G
Sbjct: 2936 KDEKSTLASKEASRRESVVESSKDDAEKSESRPESVIASGEPVPRESKSPLDSKDTSRPG 2995
Query: 470 SASES----DEQKQEQEQNNT--------TKDDVQTTDTSSQNGNDTTEKQNETSEDA-- 515
S ES DE+ ++Q + + TK D ++ + S + D K ++ +++
Sbjct: 2996 SMVESVTAEDEKSEQQSRRESVAESVKADTKKDGKSQEASRPSSVDELLKDDDEKQESRR 3055
Query: 516 ----NSKKEDSSALNTTPNNEDSKSGVAGDQADSTTTTSSSETQDGNTNHGEYKDTTNEN 571
S K S+ + +P ++ KS + T+D + G +D+ E+
Sbjct: 3056 QSITGSHKAMSTMGDESPMDKADKSKEPSRPESVAESIKHENTKDEESPLGSRRDSVAES 3115
Query: 572 -------------PEKN-SGQEGTQESGSSSNTFDNKDAASNKVQLTTTSDTSSEQKKDE 617
P K S E S +++ + V+ ++ D +S E
Sbjct: 3116 IKSDITKGEKSPLPSKEVSRPESVVGSIKDEKAESRRESVAESVKPESSKDATSAPPSKE 3175
Query: 618 SSSAESKSESSQNDNANSGQSNTTSDESANDNKD--SSQVTTSSENSAEGNSNTENNSDE 675
S ES S +++ + + +S D K SQ + E+ AE + S E
Sbjct: 3176 HSRPESVLGSLKDEGDKTTSRRVSVADSIKDEKSLLVSQEASRPESEAESLKDAAAPSQE 3235
Query: 676 NQNDSKNNENTND------SGNTSNDANVNENQNENAAQTKTSENEGDAQNESVESKKEN 729
E+ D S S A+V EN ++A ++K E Q+++ K E
Sbjct: 3236 TSRPESVTESVKDGKSPVASKEASRPASVAENAKDSADESKEQRPESLPQSKAGSIKDEK 3295
Query: 730 NESAHKDVDNNSNSNDQGSS 749
+ A KD S + S
Sbjct: 3296 SPLASKDEAEKSKEESRRES 3315
Score = 74.3 bits (181), Expect = 1e-12
Identities = 127/597 (21%), Positives = 239/597 (39%), Gaps = 87/597 (14%)
Query: 127 NAKTDLEGEQHTEKVDEENDNAEN--------KENESVEKENEEIKKEVEDTETGESIEE 178
+A D + + E + E D+ E + +++ ++ + EV D E E
Sbjct: 1169 SATKDAPKDANAEALGELPDSGERVLPMKMTFEAQQNLLRDVIKTPDEVADLPVHE--EA 1226
Query: 179 KSHLENEESKETGEISEEKSHLENEESKETGESSEEKSHLENEESKETGESSEEKSHLEN 238
L ++S++ G ++ SH E E +KE E+ +EK + E + + SH+
Sbjct: 1227 DLGLYEKDSQDAG--AKSISHKE-ESAKEEKETDDEKENKVGEIELGDEPNKVDISHVLL 1283
Query: 239 EENKDE--EK--------SKQENEEIKDGEKIQQENEEN-----KDEEKSQQENEENKDE 283
+E+ E EK K++ E ++ I QEN+E+ KD+E+ +Q+ E
Sbjct: 1284 KESVQEVAEKVVVIETTVEKKQEEIVEATTVITQENQEDLMEQVKDKEEHEQKIESGIIT 1343
Query: 284 EKSQQENELKKNEGGEKETGEITEE---------------KSKQENEETSETNSK---DK 325
EK E + + EKET +IT + KS ++ E+T S ++
Sbjct: 1344 EK---EAKKSASTPEEKETSDITSDDELPAQLADPTTVPPKSAKDREDTGSIESPPTIEE 1400
Query: 326 ENEESNQNGSDAKEQVGENHE----QDSKQGTEETNGTE---GGEKEEHDKIKEDTS--- 375
E Q +A++ V E + S ++ET+ E G KE+ ++ K S
Sbjct: 1401 AIEVEVQAKQEAQKPVPAPEEAIKTEKSPLASKETSRPESATGSVKEDTEQTKSKKSPVP 1460
Query: 376 --SDNQVQDGEKNNEAREENYSGDNASSAVVDNKSQESSNKTEEQFDKKEKNEFELESQK 433
+++ +D +K+ A E ++ + +V D + S + E K K+E L+ K
Sbjct: 1461 SRPESEAKD-KKSPFASGEASRPESVAESVKDEAGKAESRR--ESIAKTHKDESSLDKAK 1517
Query: 434 NSNETTESTDSTITQNSQGNE----SEKDQAQTENDTPKGSASESDEQKQEQEQNNTTKD 489
ES +I S +E + K+ ++ E+ T K E E + +TKD
Sbjct: 1518 EQESRRESLAESIKPESGIDEKSALASKEASRPESVTDKSKEPSRRESIAESLKAESTKD 1577
Query: 490 D--VQTTDTSSQNGNDTTEKQNETSEDANSKKEDSSALNTTP--------NNEDSKSGVA 539
+ + +S+ G+ ++ET + + +S A + P E G+
Sbjct: 1578 EKSAPPSKEASRPGSVVESVKDETEKSKEPSRRESIAESAKPPIEFREVSRPESVIDGIK 1637
Query: 540 GDQADSTTTTSSSETQDGNTNHGEYKDTTNENPEKN---SGQEGTQESGSSSNTFDNKDA 596
+ A + S + ++ + P K+ S +E ES + +T D K
Sbjct: 1638 DESAKPESRRDSPLASKEASRPESVLESVKDEPIKSTEKSRRESVAESFKADSTKDEKS- 1696
Query: 597 ASNKVQLTTTSDTSSEQKKDESSSAESKSESSQNDNANSGQSNTTSDESANDNKDSS 653
LT+ + E + A +E SQ ++ + + + + A KD +
Sbjct: 1697 -----PLTSKDISRPESAVENVMDAVGSAERSQPESVTASRDVSRPESVAESEKDDT 1748
Score = 71.2 bits (173), Expect = 1e-11
Identities = 133/626 (21%), Positives = 255/626 (40%), Gaps = 76/626 (12%)
Query: 57 EVVKLGRKDLKPRVEETSVIDARHKEDEEEADELDNKHDEQTKLDDVNGVEDNSEHKEDS 116
EV++ K ++ +V+ TSV A + ++L K EQ L ++ V D + +
Sbjct: 4206 EVLESSVKQVEEKVQ-TSVKQAETTVTDS-LEQLTKKSSEQ--LTEIKSVLDTNFEEVAK 4261
Query: 117 VEQE------SEESSQNAKTDLEGEQHTEKVDEENDNAENKENESVEKENEEIKKEVE-- 168
+ + S++ + D + Q EK+ D E + + ++++ EI +VE
Sbjct: 4262 IVADVAKVLKSDKDITDIIPDFDERQLEEKLKSTADTEEESDKSTRDEKSLEISVKVEIE 4321
Query: 169 ------DTETGE-SIEEKSHLENEESKETGEISEEKSHLENEESKETGESSEEKSHLENE 221
D ++G SIEEK +E E + + S E+ S+ S +S
Sbjct: 4322 SEKSSPDQKSGPISIEEKDKIEQSEKAQLRQGILTSSRPESVASQPESVPSPSQS----- 4376
Query: 222 ESKETGESSEEKSHLENEENKDEEKSKQENEEIKDGEKIQQENEENKDEEKSQQENEENK 281
S E K +E +K E+ S+ E+ + EK + + ++ + Q + +
Sbjct: 4377 -----AASHEHKEVELSESHKAEKSSRPESVASQVSEK---DMKTSRPASSTSQFSTKEG 4428
Query: 282 DEEKSQQENELKKNEGGEKETGEITEEKSKQENEETSETNSKDKENEESNQNGSDAKEQV 341
DEE + E+ L E + EEKS E+ TS T S ++ + Q ++ +
Sbjct: 4429 DEETT--ESLLHSLTTTETVETKQMEEKSSFESVSTSVTKSTVLSSQSTVQLREESTSES 4486
Query: 342 GENH---EQDSKQGTEETNGTEGGEKEEHDKIKEDTS-SDNQVQDGEKNNEAREENYSGD 397
+ E S++ + + E G + +KEDTS S +Q+++ + E S +
Sbjct: 4487 LSSSLKVEDSSRRESLSSLLAEKGGIATNTSLKEDTSASASQLEE----LLVQSEECSSE 4542
Query: 398 NASSAVVDNKSQESSNKTEEQFDKKEKNEFELESQKNSNETTESTDSTITQNSQGNESEK 457
+ S + + +Q+S+ + ++ + K ++F +T S+ T++ E+
Sbjct: 4543 SIVSEIQTSIAQKSNKEIKDARETKVTSQF------------TTTTSSATKDDSLKETVA 4590
Query: 458 DQAQTENDTPKGSASESDEQKQEQE-QNNTTKDDVQTTDTSSQN---GNDTTEKQNETSE 513
+ TE A ++ K + TT V +T S + G D + +++ S+
Sbjct: 4591 EFLATEKIVSAKEAFSTEATKSADDCLKKTTASAVSSTSASQRALFVGTDESRRESLLSQ 4650
Query: 514 DANSKKEDSSALNTTPNNE-DSKSGVAGDQADSTTTTSSSETQDGNTNHGEYKDTTNENP 572
+ S+ S + P ++ D +S V ++ S T + + + E
Sbjct: 4651 ASESRLTHSDPEDEEPADDVDERSSVKESRSKSIATIMMTSIYKPSEDMEPISKLVEE-- 4708
Query: 573 EKNSGQEGTQESGSSSNTFDNKDAASNKVQLTTTSDTSSEQKKDESSSAESKSESSQNDN 632
E +E QE S+S TTT SSEQ +SS SK+ +S+ ++
Sbjct: 4709 EHEHVEELAQEVTSTSK--------------TTTLLQSSEQSSTTTSST-SKTGASRVES 4753
Query: 633 ANSGQSNTTSDESANDNKDSSQVTTS 658
Q + + +S D D T+
Sbjct: 4754 ITLTQMDQQTSQSQGDPADRKTPPTA 4779
>SR40_YEAST (P32583) Suppressor protein SRP40
Length = 406
Score = 122 bits (306), Expect = 4e-27
Identities = 74/319 (23%), Positives = 164/319 (51%), Gaps = 14/319 (4%)
Query: 464 NDTPKGSASESDEQKQEQEQNNTTKDDVQTTDTSSQNGNDTTEKQNETSEDANSKKEDSS 523
++ PK S E + +++ ++++ ++ +SS + + + E + +S ++S DSS
Sbjct: 9 DEVPKLSVKEKEIEEKSSSSSSSSSSSSSSSSSSSSSSSSSGESSSSSSSSSSSSSSDSS 68
Query: 524 ALNTTPNNEDSKSGVAGDQADSTTTTSSSETQDGNTNHGEYKDTTNENPEKNSGQEGTQE 583
+ ++E S S + + S+++ S S ++ +++ G +++ + E +S E E
Sbjct: 69 ---DSSDSESSSSSSSSSSSSSSSSDSESSSESDSSSSGSSSSSSSSSDESSSESESEDE 125
Query: 584 SGSSSNTFDNKDAASNKVQLTTTSDTSSEQKKDESSSAESKSESSQNDNANSGQSNTTSD 643
+ + DN+DA K T +SS + SS+ S+SES +++S S+++S
Sbjct: 126 TKKRARESDNEDAKETKKAKTEPESSSSSESSSSGSSSSSESESGSESDSDSSSSSSSSS 185
Query: 644 ESANDNKDSSQVTTSSENSAEGNSNTENNSDENQNDSKNNENTNDSGNTSNDANVNENQN 703
+S +D++ SQ ++SS +S++ +S+++++S ++ +DS DS ++S+ ++ + + +
Sbjct: 186 DSESDSESDSQ-SSSSSSSSDSSSDSDSSSSDSSSDS-------DSSSSSSSSSSDSDSD 237
Query: 704 ENAAQTKTSENEGDAQNESVESKKENNESAHKDVDNNSNSNDQGSSDTSVTQDDKESRVD 763
+++ S D+ + S S E+ S D D++S D GSS T++
Sbjct: 238 SDSSSDSDSSGSSDSSSSSDSSSDESTSSDSSDSDSDS---DSGSSSELETKEATADESK 294
Query: 764 LGTLPESNGESHHNDVSSA 782
P S+ ES + SS+
Sbjct: 295 AEETPASSNESTPSASSSS 313
Score = 120 bits (301), Expect = 1e-26
Identities = 71/320 (22%), Positives = 164/320 (51%), Gaps = 10/320 (3%)
Query: 454 ESEKDQAQTENDTPKGSASESDEQKQEQEQNNTTKDDVQTTDTSSQNGNDTTEKQNETSE 513
E E+ + + + + S+S S ++ ++ +SS + +D+++ ++ +S
Sbjct: 20 EIEEKSSSSSSSSSSSSSSSSSSSSSSSSSGESSSSSSSSSSSSSSDSSDSSDSESSSSS 79
Query: 514 DANSKKEDSSALNTTPNNEDSKSGVAGDQADSTTTTSSSETQDGNTNHGEYKDTTNENPE 573
++S SS+ + + + DS S + + S++ SSSE++ + +++ NE+ +
Sbjct: 80 SSSSSSSSSSSDSESSSESDSSSSGSSSSSSSSSDESSSESESEDETKKRARESDNEDAK 139
Query: 574 KNSGQEGTQESGSSSNTFDNKDAASNKVQLTTTSDTSSEQKKDESSSAESKSESSQNDNA 633
+ + ES SSS + + ++S++ + + SD+ S SS +ES SES ++
Sbjct: 140 ETKKAKTEPESSSSSESSSSGSSSSSESESGSESDSDSSSSSSSSSDSESDSESDSQSSS 199
Query: 634 NSGQSNTTSD---ESANDNKDSSQVTTSSENSAEGNSNTENNSDENQNDSKNNENTNDSG 690
+S S+++SD S++ + DS ++SS +S++ +S+++++SD + + S ++ +++DS
Sbjct: 200 SSSSSDSSSDSDSSSSDSSSDSDSSSSSSSSSSDSDSDSDSSSDSDSSGSSDSSSSSDSS 259
Query: 691 ---NTSNDANVNENQNENAAQTKTSENEGDAQNESVE----SKKENNESAHKDVDNNSNS 743
+TS+D++ +++ +++ + ++ E A E S E+ SA N +
Sbjct: 260 SDESTSSDSSDSDSDSDSGSSSELETKEATADESKAEETPASSNESTPSASSSSSANKLN 319
Query: 744 NDQGSSDTSVTQDDKESRVD 763
G+ + Q SRVD
Sbjct: 320 IPAGTDEIKEGQRKHFSRVD 339
Score = 115 bits (287), Expect = 6e-25
Identities = 88/373 (23%), Positives = 181/373 (47%), Gaps = 26/373 (6%)
Query: 369 KIKEDTSSDNQVQDGEKNNEAREENYSGDNASSAVVDNKSQESSNKTEEQFDKKEKNEFE 428
KIK D V+ EK E + + S ++SS+ + S SS+ + E
Sbjct: 5 KIKVDEVPKLSVK--EKEIEEKSSSSSSSSSSSSSSSSSSSSSSSSSGESSSSS------ 56
Query: 429 LESQKNSNETTESTDSTITQNSQGNESEKDQAQTENDTPKGSASESDEQKQEQEQNNTTK 488
S +S+ +++S+DS+ +++S + S + + +D+ S+SESD ++++
Sbjct: 57 --SSSSSSSSSDSSDSSDSESSSSSSSSSSSSSSSSDSE--SSSESDSSSSGSSSSSSSS 112
Query: 489 DDVQTTDTSSQNGNDTTEKQNETSEDANSKKEDSSALNTTPNNEDSKSGVAGDQADSTTT 548
D ++++ S++ ++++ +EDA K+ + ++ ++E S SG +
Sbjct: 113 SDESSSESESEDETKKRARESD-NEDAKETKKAKTEPESSSSSESSSSG----------S 161
Query: 549 TSSSETQDGNTNHGEYKDTTNENPEKNSGQEGTQESGSSSNTFD-NKDAASNKVQLTTTS 607
+SSSE++ G+ + + +++ + + S E +S SSS++ D + D+ S+ ++ S
Sbjct: 162 SSSSESESGSESDSDSSSSSSSSSDSESDSESDSQSSSSSSSSDSSSDSDSSSSDSSSDS 221
Query: 608 DTSSEQKKDESSSAESKSESSQNDNANSGQSNTTSDESANDNKDSSQVTTSSENSAEGNS 667
D+SS S S SS +D++ S S+++SD S++D SS + S +S G+S
Sbjct: 222 DSSSSSSSSSSDSDSDSDSSSDSDSSGSSDSSSSSD-SSSDESTSSDSSDSDSDSDSGSS 280
Query: 668 NTENNSDENQNDSKNNENTNDSGNTSNDANVNENQNENAAQTKTSE-NEGDAQNESVESK 726
+ + ++SK E S ++ A+ + + N+ T E EG ++ S +
Sbjct: 281 SELETKEATADESKAEETPASSNESTPSASSSSSANKLNIPAGTDEIKEGQRKHFSRVDR 340
Query: 727 KENNESAHKDVDN 739
+ N A + DN
Sbjct: 341 SKINFEAWELTDN 353
Score = 112 bits (279), Expect = 5e-24
Identities = 82/390 (21%), Positives = 182/390 (46%), Gaps = 24/390 (6%)
Query: 309 KSKQENEETSETNSKDKENEESNQNGSDAKEQVGENHEQDSKQGTEETN-GTEGGEKEEH 367
K K+ E++S ++S + S+ + S + GE+ S + ++ ++ + E
Sbjct: 17 KEKEIEEKSSSSSSSSSSSSSSSSSSSSSSSSSGESSSSSSSSSSSSSSDSSDSSDSESS 76
Query: 368 DKIKEDTSSDNQVQDGEKNNEAREENYSGDNASSAVVDNKSQESSNKTEEQFDKKEKNEF 427
+SS + D E ++E+ + ++SS+ D S ES ++ E + +E +
Sbjct: 77 SSSSSSSSSSSSSSDSESSSESDSSSSGSSSSSSSSSDESSSESESEDETKKRARESDNE 136
Query: 428 ELESQKNSNETTESTDSTITQNSQGNESEKDQAQTENDTPKGSASESDEQKQEQEQNNTT 487
+ + K + ES+ S+ + +S + S + ++ +E+D+ S+S S + ++
Sbjct: 137 DAKETKKAKTEPESSSSSESSSSGSSSSSESESGSESDSDSSSSSSSSSDSESDSES--- 193
Query: 488 KDDVQTTDTSSQNGNDTTEKQNETSEDANSKKEDSSALNTTPNNEDSKSGVAGDQADSTT 547
D Q+ +SS + +D++ + +S D++S + SS+ +++ ++ DS S + D +DS+
Sbjct: 194 --DSQS--SSSSSSSDSSSDSDSSSSDSSSDSDSSSSSSSSSSDSDSDSDSSSD-SDSSG 248
Query: 548 TTSSSETQDGNTNHGEYKDTTNENPEKNSGQEGTQESGSSSNTFDNKDAAS--NKVQLTT 605
++ SS + D +++ D+++ + + +SG SS+ + K+A + +K + T
Sbjct: 249 SSDSSSSSDSSSDESTSSDSSDSDSDSDSG---------SSSELETKEATADESKAEETP 299
Query: 606 TSDTSSEQKKDESSSAESKSESSQNDNANSGQSNTTSD-ESANDNKDSSQVTTSSENSAE 664
S S SSSA + + D GQ S + + N ++ ++T ++ A
Sbjct: 300 ASSNESTPSASSSSSANKLNIPAGTDEIKEGQRKHFSRVDRSKINFEAWELTDNTYKGAA 359
Query: 665 GNSNTENNSDENQ---NDSKNNENTNDSGN 691
G + N + D N+N G+
Sbjct: 360 GTWGEKANEKLGRVRGKDFTKNKNKMKRGS 389
Score = 112 bits (279), Expect = 5e-24
Identities = 62/323 (19%), Positives = 166/323 (51%), Gaps = 4/323 (1%)
Query: 455 SEKDQAQTENDTPKGSASESDEQKQEQEQNNTTKDDVQTTDTSSQNGNDTTEKQNETSED 514
S K++ E + S+S S ++++ ++ +SS + + +++ + S D
Sbjct: 15 SVKEKEIEEKSSSSSSSSSSSSSSSSSSSSSSSSSGESSSSSSSSSSSSSSDSSD--SSD 72
Query: 515 ANSKKEDSSALNTTPNNEDSKSGVAGDQADSTTTTSSSETQDGNTNHGEYKDTTNENPEK 574
+ S SS+ +++ ++ DS+S D + S +++SSS + D +++ E +D T + +
Sbjct: 73 SESSSSSSSSSSSSSSSSDSESSSESDSSSSGSSSSSSSSSDESSSESESEDETKKRARE 132
Query: 575 NSGQEGTQESGSSSNTFDNKDAASNKVQLTTTSDTSSEQKKDESSSAESKSESSQNDNAN 634
+ ++ + + + + + S+ +++S++ S + D SS+ S S S ++
Sbjct: 133 SDNEDAKETKKAKTEPESSSSSESSSSGSSSSSESESGSESDSDSSSSSSSSSDSESDSE 192
Query: 635 SGQSNTTSDESANDNKDSSQVTTSSENSAEGNSNTENNSDENQNDSKNNENTNDSGNTSN 694
S +++S S++ + DS ++ S + ++ +S++ ++S ++ +DS ++ +++ SG++ +
Sbjct: 193 SDSQSSSSSSSSDSSSDSDSSSSDSSSDSDSSSSSSSSSSDSDSDSDSSSDSDSSGSSDS 252
Query: 695 DANVNENQNEN-AAQTKTSENEGDAQNESVESKKENNESAHKDVDNNSNSNDQGSSDTSV 753
++ + + +E+ ++ + S+++ D+ + S KE K + ++SN+ S +S
Sbjct: 253 SSSSDSSSDESTSSDSSDSDSDSDSGSSSELETKEATADESKAEETPASSNESTPSASSS 312
Query: 754 TQDDKESRVDLGTLPESNGESHH 776
+ +K + GT G+ H
Sbjct: 313 SSANK-LNIPAGTDEIKEGQRKH 334
Score = 108 bits (271), Expect = 4e-23
Identities = 61/277 (22%), Positives = 149/277 (53%), Gaps = 9/277 (3%)
Query: 507 KQNETSEDANSKKEDSSALNTTPNNEDSKSGVAGDQADSTTTTSSSETQDGNTNHGEYKD 566
K+ E E ++S SS+ +++ ++ S S +G+ + S++++SSS + D + +
Sbjct: 17 KEKEIEEKSSSSSSSSSSSSSSSSSSSSSSSSSGESSSSSSSSSSSSSSDSSDSSDSESS 76
Query: 567 TTNENPEKNSGQEGTQESGSSSNTFDNKDAASNKVQLTTTSDTSSEQKKDESSSAESKSE 626
+++ + +S ES S S++ + ++S+ +++SD SS + + E + + ++
Sbjct: 77 SSSSSSSSSSSSSSDSESSSESDSSSSGSSSSS----SSSSDESSSESESEDET-KKRAR 131
Query: 627 SSQNDNANSGQSNTTSDESANDNKDSSQVTTSSENSAEGNSNTENNSDENQNDSKNNENT 686
S N++A + T ES++ ++ SS + S +S+E S +E++SD + + S ++++
Sbjct: 132 ESDNEDAKETKKAKTEPESSSSSESSS---SGSSSSSESESGSESDSDSSSSSSSSSDSE 188
Query: 687 NDSGNTSNDANVNENQNENAAQTKTSENEGDAQNESVESKKENNESAHKDVDNNSNSNDQ 746
+DS + S ++ + + +++++ + +S ++ + ++S S ++ + D D++S+S+
Sbjct: 189 SDSESDSQSSS-SSSSSDSSSDSDSSSSDSSSDSDSSSSSSSSSSDSDSDSDSSSDSDSS 247
Query: 747 GSSDTSVTQDDKESRVDLGTLPESNGESHHNDVSSAE 783
GSSD+S + D +S+ +S S E
Sbjct: 248 GSSDSSSSSDSSSDESTSSDSSDSDSDSDSGSSSELE 284
Score = 106 bits (265), Expect = 2e-22
Identities = 88/418 (21%), Positives = 187/418 (44%), Gaps = 40/418 (9%)
Query: 338 KEQVGENHEQDSKQGTEETNGTEGGEKEEHDKIKEDTSSDNQVQDGEKNNEAREENYSGD 397
K +V E + K+ E + +SS + GE ++ + + S
Sbjct: 5 KIKVDEVPKLSVKEKEIEEKSSSSSSSSSSSSSSSSSSSSSSSSSGESSSSSSSSSSSSS 64
Query: 398 NASSAVVDNKSQESSNKTEEQFDKKEKNEFELESQKNSNETTESTDSTITQNSQGNESEK 457
+ SS D++S SS+ + +E ES +S+ ++ S+ S+ ++S +ESE
Sbjct: 65 SDSSDSSDSESSSSSSSSSSSSSSSSDSESSSESDSSSSGSSSSSSSSSDESSSESESED 124
Query: 458 DQAQTENDTPKGSASESDEQKQEQEQNNTTKDDVQTTDTSSQNGNDTTEKQNETSEDANS 517
+ + ++ A E+ + K E E +++++ + +SS++ + + + +S ++S
Sbjct: 125 ETKKRARESDNEDAKETKKAKTEPESSSSSESSSSGSSSSSESESGSESDSDSSSSSSSS 184
Query: 518 KKEDSSALNTTPNNEDSKSGVAGDQADSTTTTSSSETQDGNTNHGEYKDTTNENPEKNSG 577
+S + + + ++ S S + +DS+++ SSS++ D+++ + +S
Sbjct: 185 SDSESDSESDSQSSSSSSSSDSSSDSDSSSSDSSSDS-----------DSSSSSSSSSSD 233
Query: 578 QEGTQESGSSSNTFDNKDAASNKVQLTTTSDTSSEQKKDESSSAESKSESSQNDNANSGQ 637
+ +S S S++ + D++S SS+ DES+S++S S +D+ +S +
Sbjct: 234 SDSDSDSSSDSDSSGSSDSSS-----------SSDSSSDESTSSDSSDSDSDSDSGSSSE 282
Query: 638 SNT---TSDESANDN--KDSSQVTTSSENSAEGNS-NTENNSDENQNDSKNNENTNDSGN 691
T T+DES + S++ T S+ +S+ N N +DE + + + + D
Sbjct: 283 LETKEATADESKAEETPASSNESTPSASSSSSANKLNIPAGTDEIKEGQRKHFSRVDRSK 342
Query: 692 TSNDA-NVNENQNENAAQTKTSENEGDAQNESVESKKENNESAHKDVDNNSNSNDQGS 748
+ +A + +N + AA T G+ NE + KD N N +GS
Sbjct: 343 INFEAWELTDNTYKGAAGT-----WGEKANEKL------GRVRGKDFTKNKNKMKRGS 389
Score = 102 bits (253), Expect = 5e-21
Identities = 78/414 (18%), Positives = 169/414 (39%), Gaps = 48/414 (11%)
Query: 193 ISEEKSHLENEESKETGESSEEKSHLENEESKETGESSEEKSHLENEENKDEEKSKQENE 252
+ E++ ++ S + SS S + S +GESS S + + D S
Sbjct: 16 VKEKEIEEKSSSSSSSSSSSSSSSSSSSSSSSSSGESSSSSSSSSSSSSSDSSDSS---- 71
Query: 253 EIKDGEKIQQENEENKDEEKSQQENEENKDEEKSQQENELKKNEGGEKETGEITEEKSKQ 312
+ E+ S + + + +S E++ + + E S+
Sbjct: 72 -----------DSESSSSSSSSSSSSSSSSDSESSSESDSSSSGSSSSSSSSSDESSSES 120
Query: 313 ENEETSETNSKDKENEESNQNGSDAKEQVGENHEQDSKQGTEETNGTEGGEKEEHDKIKE 372
E+E+ ++ +++ +NE++ + E + + S G+ ++ +E G + + D
Sbjct: 121 ESEDETKKRARESDNEDAKETKKAKTEPESSSSSESSSSGSSSSSESESGSESDSDSSSS 180
Query: 373 DTSSDNQVQDGEKNNEAREENYSGDNASSAVVDNKSQESSNKTEEQFDKKEK---NEFEL 429
+SS + D E ++++ + S D++S + D+ S +SS+ ++ ++ +
Sbjct: 181 SSSSSDSESDSESDSQSSSSSSSSDSSSDS--DSSSSDSSSDSDSSSSSSSSSSDSDSDS 238
Query: 430 ESQKNSNETTESTDSTITQNSQGNESEKDQAQTENDTPKGSASE-------SDEQKQEQE 482
+S +S+ + S S+ + +S + D + +++D+ GS+SE +DE K E+
Sbjct: 239 DSSSDSDSSGSSDSSSSSDSSSDESTSSDSSDSDSDSDSGSSSELETKEATADESKAEET 298
Query: 483 QNNTTKDDVQTTDTSSQN-------GNDTTEKQNETSEDANSKKEDSSALNTTPNNEDSK 535
++ + + +SS N ++ E Q + + K + A T N
Sbjct: 299 PASSNESTPSASSSSSANKLNIPAGTDEIKEGQRKHFSRVDRSKINFEAWELTDNTYKGA 358
Query: 536 SGVAGDQADSTTTTSSSETQDGNTNHGEYKDTTNENPEKNSGQEG---TQESGS 586
+G G++A+ G ++ T N+N K G T ESGS
Sbjct: 359 AGTWGEKANEKL---------GRVRGKDF--TKNKNKMKRGSYRGGSITLESGS 401
Score = 97.1 bits (240), Expect = 2e-19
Identities = 80/395 (20%), Positives = 164/395 (41%), Gaps = 28/395 (7%)
Query: 158 KENEEIKKEVEDTETGESIEEKSHLENEESKETGEISEEKSHLENEESKETGESSEEKSH 217
K +E K V++ E IEEKS + S + S S S +GESS S
Sbjct: 7 KVDEVPKLSVKEKE----IEEKSSSSSSSSSSSSSSSSSSS----SSSSSSGESSSSSSS 58
Query: 218 LENEESKETGESSEEKSHLENEENKDEEKSKQENEEIKDGEKIQQENEENKDEEKSQQEN 277
+ S ++ +SS+ +S + + S ++E + + + + S +
Sbjct: 59 SSSSSSSDSSDSSDSESSSSSSSSSSSSSSSSDSESSSESD-----SSSSGSSSSSSSSS 113
Query: 278 EENKDEEKSQQENELKKNEGGEKETGEITEEKSKQENEETSETNSKDKENEESNQNGS-- 335
+E+ E +S+ E + + E ++ E + K++ E+ +SE++S + +++GS
Sbjct: 114 DESSSESESEDETKKRARESDNEDAKETKKAKTEPESSSSSESSSSGSSSSSESESGSES 173
Query: 336 DAKEQVGENHEQDSKQGTEETNGTEGGEKEEHDKIKEDTSSDNQVQDGEKNNEAREENYS 395
D+ + DS+ +E + + D+SS + D + ++ + +
Sbjct: 174 DSDSSSSSSSSSDSESDSESDSQSSSSSSSSDSSSDSDSSSSDSSSDSDSSSSSSSSSSD 233
Query: 396 GDNASSAVVDNKSQESSNKTEEQFDKKEKNEFELESQKNSNETTESTDSTITQNSQGNES 455
D+ S + D+ S SS+ + +++ S +S+ + S+ T+ + +ES
Sbjct: 234 SDSDSDSSSDSDSSGSSDSSSSSDSSSDESTSSDSSDSDSDSDSGSSSELETKEATADES 293
Query: 456 EKDQ--AQTENDTPKGSASES----------DEQKQEQEQNNTTKDDVQTTDTSSQNGND 503
+ ++ A + TP S+S S DE K+ Q ++ + D + + + ++
Sbjct: 294 KAEETPASSNESTPSASSSSSANKLNIPAGTDEIKEGQRKHFSRVDRSKINFEAWELTDN 353
Query: 504 TTEKQNET-SEDANSKKEDSSALNTTPNNEDSKSG 537
T + T E AN K + T N K G
Sbjct: 354 TYKGAAGTWGEKANEKLGRVRGKDFTKNKNKMKRG 388
Score = 94.4 bits (233), Expect = 1e-18
Identities = 67/331 (20%), Positives = 141/331 (42%), Gaps = 21/331 (6%)
Query: 124 SSQNAKTDLEGEQHTEKVDEENDNAENKENESVEKENEEIKKEVEDTETGESIEEKSHLE 183
+S+ K D E + + K E + + + + S + + +GES S
Sbjct: 2 ASKKIKVD-EVPKLSVKEKEIEEKSSSSSSSSSSSSSSSSSSSSSSSSSGESSSSSSSSS 60
Query: 184 NEESKETGEISEEKSHLENEESKETGESSEEKSHLENEESKETGESSEEKSHLENEENKD 243
+ S ++ + S+ +S + S + SS + +S +G SS S + D
Sbjct: 61 SSSSSDSSDSSDSESSSSSSSSSSSSSSSSDSESSSESDSSSSGSSSSSSS------SSD 114
Query: 244 EEKSKQENEEIKDGEKIQQENEENKDEEKSQQENEENKDEEKSQ--QENELKKNEGGEKE 301
E S+ E+E+ + +NE+ K+ +K++ E E + E S + + G E +
Sbjct: 115 ESSSESESEDETKKRARESDNEDAKETKKAKTEPESSSSSESSSSGSSSSSESESGSESD 174
Query: 302 TGEITEEKSKQENEETSETNSKDKENEESNQNGSDAKEQVGENHEQDSKQGTEETNGTEG 361
+ + S ++E SE++S+ + S+ + SD+ + S + +++ +
Sbjct: 175 SDSSSSSSSSSDSESDSESDSQSSSSSSSSDSSSDS--------DSSSSDSSSDSDSSSS 226
Query: 362 GEKEEHDKIKEDTSSDNQVQDGEKNNEAREENYSGDNASSAVVDNKSQESSNKTEEQFDK 421
D + SS + G ++ + ++ S ++ SS D+ S S + E +
Sbjct: 227 SSSSSSDSDSDSDSSSDSDSSGSSDSSSSSDSSSDESTSSDSSDSDSDSDSGSSSE-LET 285
Query: 422 KEKNEFELESQK---NSNETTESTDSTITQN 449
KE E ++++ +SNE+T S S+ + N
Sbjct: 286 KEATADESKAEETPASSNESTPSASSSSSAN 316
Score = 94.0 bits (232), Expect = 1e-18
Identities = 70/377 (18%), Positives = 150/377 (39%), Gaps = 29/377 (7%)
Query: 118 EQESEESSQNAKTDLEGEQHTEKVDEENDNAENKENESVEKENEEIKKEVEDTETGESIE 177
E+E EE S ++ + + + ++ + + S + + D+ ES
Sbjct: 18 EKEIEEKSSSSSSSSSSSSSSSSSSSSSSSSSGESSSSSSSSSSSSSSDSSDSSDSESSS 77
Query: 178 EKSHLENEESKETGEISEEKSHLENEESKETGESSEEKSHLENEESKETGESSEEKSHLE 237
S + S + S +S + S + SS ++S E+E ET + + E +
Sbjct: 78 SSSSSSSSSSSSSDSESSSESDSSSSGSSSSSSSSSDESSSESESEDETKKRARES---D 134
Query: 238 NEENKDEEKSKQENEEIKDGEKIQQENEENKDEEKSQQENEENKDEEKSQQENELKKNEG 297
NE+ K+ +K+K E E E + + + E + + ++ S ++E
Sbjct: 135 NEDAKETKKAKTEPESSSSSESSSSGSSSSSESESGSESDSDSSSSSSSSSDSESDSESD 194
Query: 298 GEKETGEITEEKSKQENEETSETNSKDKENEESNQNGSDAKEQVGENHEQDSKQGTEETN 357
+ + + + S + +S+++S + S+ + SD+ + + DS ++ ++
Sbjct: 195 SQSSSSSSSSDSSSDSDSSSSDSSSDSDSSSSSSSSSSDSDSDSDSSSDSDSSGSSDSSS 254
Query: 358 GTEGGEKEEHDKIKEDTSSDN--------QVQDGEKNNEAREENYSGDNASSAVVDNKSQ 409
++ E D+ SD+ + ++ + EE + N S+ + S
Sbjct: 255 SSDSSSDESTSSDSSDSDSDSDSGSSSELETKEATADESKAEETPASSNESTPSASSSS- 313
Query: 410 ESSNK------TEEQFDKKEKNEFELESQKNSNETTESTDSTI-----TQNSQGNES--- 455
S+NK T+E + + K+ ++ K + E E TD+T T + NE
Sbjct: 314 -SANKLNIPAGTDEIKEGQRKHFSRVDRSKINFEAWELTDNTYKGAAGTWGEKANEKLGR 372
Query: 456 --EKDQAQTENDTPKGS 470
KD + +N +GS
Sbjct: 373 VRGKDFTKNKNKMKRGS 389
Score = 90.9 bits (224), Expect = 1e-17
Identities = 53/220 (24%), Positives = 117/220 (53%), Gaps = 9/220 (4%)
Query: 565 KDTTNENPEKNSGQEGTQESGSSSNTFDNKDAASNKVQLTTTSDTSSEQKKDESSSAESK 624
K +E P+ + ++ +E SSS++ + ++S+ +++S + SSS+ S
Sbjct: 5 KIKVDEVPKLSVKEKEIEEKSSSSSSSSSSSSSSSSSSSSSSSSSGESSSSSSSSSSSSS 64
Query: 625 SESSQNDNANSGQSNTTSDESANDNKDSSQVTTSSENSAEGNSNTENNSDENQNDSKNNE 684
S+SS + ++ S S+++S S++ + DS + S +S+ +S++ ++SDE+ ++S++ +
Sbjct: 65 SDSSDSSDSESSSSSSSSSSSSSSSSDSESSSESDSSSSGSSSSSSSSSDESSSESESED 124
Query: 685 NTNDSGNTSNDANVNENQNENAAQTKTSENEGDAQNESVESKKENNESAHKDVDNNSNSN 744
T E+ NE+A +TK ++ E ++ + S S ++ S+ + + S+S+
Sbjct: 125 ETK--------KRARESDNEDAKETKKAKTEPESSSSSESSSSGSSSSSESESGSESDSD 176
Query: 745 DQGSSDTSV-TQDDKESRVDLGTLPESNGESHHNDVSSAE 783
SS +S ++ D ES + S+ S +D SS++
Sbjct: 177 SSSSSSSSSDSESDSESDSQSSSSSSSSDSSSDSDSSSSD 216
Score = 90.5 bits (223), Expect = 2e-17
Identities = 69/400 (17%), Positives = 160/400 (39%), Gaps = 30/400 (7%)
Query: 67 KPRVEETSVIDARHKEDEEEADELDNKHDEQTKLDDVNGVEDNSEHKEDSVEQESEESSQ 126
K +V+E + + KE EE++ + + + +S + S S SS
Sbjct: 5 KIKVDEVPKLSVKEKEIEEKSSSSSSSSSSSSSSSSSSSSSSSSSGESSSSSSSSSSSSS 64
Query: 127 NAKTDLEGEQHTEKVDEENDNAENKENESVEKENEEIKKEVEDTETGESIEEKSHLENEE 186
+ +D + + + ++ + + E++ + + S E S E+E
Sbjct: 65 SDSSDSSDSESSSSSSSSSSSSSSSSDSESSSESDSSSSGSSSSSSSSSDESSS--ESES 122
Query: 187 SKETGEISEEKSHLENEESKETGESSEEKSHLENEESKETGESSEEKSHLENEENKDEEK 246
ET + + E +NE++KET ++ E + ES +G SS +S +E + D
Sbjct: 123 EDETKKRARES---DNEDAKETKKAKTEPESSSSSESSSSGSSSSSESESGSESDSDSSS 179
Query: 247 SKQENEEIK-DGEKIQQENEENKDEEKSQQENEENKD--EEKSQQENELKKNEGGEKETG 303
S + + + D E Q + + + S + + D + + + + ++
Sbjct: 180 SSSSSSDSESDSESDSQSSSSSSSSDSSSDSDSSSSDSSSDSDSSSSSSSSSSDSDSDSD 239
Query: 304 EITEEKSKQENEETSETNSKDKENEESNQNGSDAKEQVGENHEQDSKQGTEETNGTEGGE 363
++ S ++ +S ++S E+ S+ + SD+ G + E ++K+ T + + E
Sbjct: 240 SSSDSDSSGSSDSSSSSDSSSDESTSSDSSDSDSDSDSGSSSELETKEATADESKAEETP 299
Query: 364 KEEHDKIKEDTSSD-----------NQVQDGEKNNEAREENYSGDNASSAVVDN------ 406
++ +SS +++++G++ + +R + + + + DN
Sbjct: 300 ASSNESTPSASSSSSANKLNIPAGTDEIKEGQRKHFSRVDRSKINFEAWELTDNTYKGAA 359
Query: 407 -----KSQESSNKTEEQFDKKEKNEFELESQKNSNETTES 441
K+ E + + K KN+ + S + + T ES
Sbjct: 360 GTWGEKANEKLGRVRGKDFTKNKNKMKRGSYRGGSITLES 399
Score = 77.8 bits (190), Expect = 1e-13
Identities = 44/196 (22%), Positives = 109/196 (55%), Gaps = 7/196 (3%)
Query: 593 NKDAASNKVQLTTTSDTSSEQKKDESSSAES----KSESSQNDNANSGQSNTTSDESAND 648
+K ++V + + E+K SSS+ S S SS + +++SG+S+++S S++
Sbjct: 3 SKKIKVDEVPKLSVKEKEIEEKSSSSSSSSSSSSSSSSSSSSSSSSSGESSSSSSSSSSS 62
Query: 649 NKDSSQVTTSSENSAEGNSNTENNSDENQNDSKNNENTNDSG-NTSNDANVNENQNENAA 707
+ S ++ SE+S+ +S++ ++S + ++S + +++ SG ++S+ ++ +E+ +E+ +
Sbjct: 63 SSSDSSDSSDSESSSSSSSSSSSSSSSSDSESSSESDSSSSGSSSSSSSSSDESSSESES 122
Query: 708 QTKTSENEGDAQNESVESKKENNESAHKDVDNNSNSNDQGSSDTSVTQDDKESRVDLGTL 767
+ +T + ++ NE ++K+ + ++S S+ GSS +S ++ ES D +
Sbjct: 123 EDETKKRARESDNE--DAKETKKAKTEPESSSSSESSSSGSSSSSESESGSESDSDSSSS 180
Query: 768 PESNGESHHNDVSSAE 783
S+ +S + S ++
Sbjct: 181 SSSSSDSESDSESDSQ 196
Score = 65.1 bits (157), Expect = 7e-10
Identities = 56/315 (17%), Positives = 115/315 (35%), Gaps = 14/315 (4%)
Query: 41 SREQKASYGASTKTGNEVVKLGRKDLKPRVEETSVIDARHKEDEEEADELDNKHDEQTKL 100
S + ++S +S+ + + + +S + +E+ DE K
Sbjct: 70 SSDSESSSSSSSSSSSSSSSSDSESSSESDSSSSGSSSSSSSSSDESSSESESEDETKKR 129
Query: 101 DDVNGVEDNSEHKEDSVEQESEESSQNAKTDLEGEQHTEKVDEENDNAENKENESVEKEN 160
+ ED E K+ E ES SS+++ + +E E + ++ + + S + E+
Sbjct: 130 ARESDNEDAKETKKAKTEPESSSSSESSSSGSSSSSESESGSESDSDSSSSSSSSSDSES 189
Query: 161 EEIKKEVEDTETGESIEEKSHLENEESKETGEISEEKSHLENEESKETGESSEEKSHLEN 220
+ E + + S S +++ S + S + S ++ S+ S ++
Sbjct: 190 DS---ESDSQSSSSSSSSDSSSDSDSSSSDSSSDSDSSSSSSSSSSDSDSDSDSSSDSDS 246
Query: 221 EESKETGESSEEKSHLENEENKDEEKSKQENEEIKDGEKIQQENEENKDEEKSQQENEEN 280
S ++ SS+ S + + S ++ + E + +E+K EE NE
Sbjct: 247 SGSSDSSSSSDSSSDESTSSDSSDSDSDSDSGSSSELETKEATADESKAEETPASSNEST 306
Query: 281 KDEEKSQQENEL-------KKNEGGEKETGEITEEKSKQENEETSETNSKDKENEESNQN 333
S N+L + EG K + K E E ++ K +
Sbjct: 307 PSASSSSSANKLNIPAGTDEIKEGQRKHFSRVDRSKINFEAWELTDNTYKG----AAGTW 362
Query: 334 GSDAKEQVGENHEQD 348
G A E++G +D
Sbjct: 363 GEKANEKLGRVRGKD 377
>PLS_STAAU (P80544) Surface protein precursor (Plasmin-sensitive
surface protein) (230 kDa cell-wall protein)
Length = 1637
Score = 122 bits (306), Expect = 4e-27
Identities = 129/695 (18%), Positives = 274/695 (38%), Gaps = 58/695 (8%)
Query: 114 EDSVEQESEESSQNAKTDL-----------EGEQHTEKVDEENDNAENKENESVEKENEE 162
E+ V QE + + T EGE TE E D E V + +
Sbjct: 941 EEKVTQEGQTGEKTTTTPTTINPLTGEKVGEGEPTTEVTKEPVDEITQFGGEEVPQGH-- 998
Query: 163 IKKEVEDTETGESIEEKSHLENEESKETGEISEEKSHLENEESKETGESSEEKSHLENEE 222
K E + + EE ++ ETGE+ + + GE K + E+
Sbjct: 999 -KDEFDPNLPIDGTEEVPGKPGIKNPETGEVVTPPVDDVTKHGPKAGEPEVTKEEIPFEK 1057
Query: 223 SKETGESSEEKSHLENEENKDEEKSKQE--------NEEIKDGEKIQQENEENKDE---- 270
+E + +E + EK+ E++ +GE + +E DE
Sbjct: 1058 KREFNPDLKPGEEKVTQEGQTGEKTTTTPTTINPLTGEKVGEGEPTTEVTKEPVDEITQF 1117
Query: 271 --EKSQQENEENKDEEKSQQENELKKNEGGEK--ETGEITEEKSKQENEETSETNSKDKE 326
E+ Q +++ D E + G K ETGE+ + + +
Sbjct: 1118 GGEEVPQGHKDEFDPNLPIDGTEEVPGKPGIKNPETGEVVTPPVDDVTKHGPKAGEPEVT 1177
Query: 327 NEESNQNGSDAKEQVGENHEQDSKQGTEETNGTEGGEKEEHDKIKEDTSSDNQVQDGEKN 386
EE + K + E S + E GEK + + +V +GE
Sbjct: 1178 KEEIPY---ETKRVLDPTMEPGSPDKVAQKG--ENGEKTTTTPTTINPLTGEKVGEGEPT 1232
Query: 387 NEAREENYSG--DNASSAVVDNKSQESSNKTEEQFDKKEKNEFELESQKNSNETTESTDS 444
E +E + A + +E E K + L+ + E D
Sbjct: 1233 TEVTKEPIDEIVNYAPEIIPHGTREEIDPNLPEGETKVIPGKDGLKDPETGEIIEEPQDE 1292
Query: 445 TITQNSQGNESEKDQAQTENDTPKGSASESDEQKQEQEQNNTTKDDVQTTDTSSQNGNDT 504
I + KD + ++D+ S S++D ++ D +D+ S + +D
Sbjct: 1293 VIIHGA------KDDSDADSDSDADSDSDADSDSDADSDSDADSDSDSDSDSDSDSDSDA 1346
Query: 505 -TEKQNETSEDANSKKEDSSALNTTPNNEDSKSGVAGDQADSTTTTSSSETQDGNTNHGE 563
++ +++ DA+S + S + +++ + ADS + + S D +++
Sbjct: 1347 DSDSDSDSDSDADSDSDADSDSDADSDSDSDADSDSDSDADSDSDSDSDSDADSDSDSDS 1406
Query: 564 YKDTTNENP-EKNSGQEGTQESGSSSNTFDNKDAASNKVQLTTTSDTSSEQKKDESSSAE 622
D +++ + +S + ++ S S++ + DA S+ SD S+ D S A+
Sbjct: 1407 DSDADSDSDADSDSDSDSDSDADSDSDSDSDSDADSD-------SDADSDSDADSDSDAD 1459
Query: 623 SKSESSQNDNANSGQSNTTSDESANDNKDSSQVTTSSENSAEGNSNTENNSDENQNDSKN 682
S S+S + +A+S + ++ +D+ S + S++ A+ +S+++++SD + DS +
Sbjct: 1460 SDSDSDSDSDADSDSDADSDSDADSDSDADSDSDSDSDSDADSDSDSDSDSDSDA-DSDS 1518
Query: 683 NENTNDSGNTSNDANVNENQNENAAQTKTSENEGDAQNESVESKKENNESAHKDVDNNSN 742
+ +++ + +D++ + + + + S+++ D+ ++S +++ + D D +S+
Sbjct: 1519 DADSDSDSDADSDSDADSDSDADGDSDADSDSDADSDSDS-----DSDSDSDSDSDADSD 1573
Query: 743 SNDQGSSDTSVTQDDKESRVDLGTLPESNGESHHN 777
S+ SD +DK + + LP++ ++ +N
Sbjct: 1574 SDSDSDSDADRDHNDKTDKPNNKELPDTGNDAQNN 1608
Score = 118 bits (295), Expect = 7e-26
Identities = 136/695 (19%), Positives = 284/695 (40%), Gaps = 52/695 (7%)
Query: 43 EQKASYGASTKTGNE-VVKLGRKDLKPRVEETSVIDARHKEDEEEADELDNKHDEQTKLD 101
E+K + K G E V + G+ K T++ ++ E + + ++
Sbjct: 928 EKKREFNPDLKPGEEKVTQEGQTGEKTTTTPTTINPLTGEKVGEGEPTTEVTKEPVDEIT 987
Query: 102 DVNGVEDNSEHKEDSVEQ------ESEESSQNAKTDLEGEQHTEKVDEENDNAENKENES 155
G E HK++ E K GE T VD+ +
Sbjct: 988 QFGGEEVPQGHKDEFDPNLPIDGTEEVPGKPGIKNPETGEVVTPPVDDVTKHGPKAGEPE 1047
Query: 156 VEKENEEIKKEVEDTETGESIEEKSHLENEESKET-----------------GEISEEKS 198
V KE +K+ E + EEK E + ++T GE + E +
Sbjct: 1048 VTKEEIPFEKKREFNPDLKPGEEKVTQEGQTGEKTTTTPTTINPLTGEKVGEGEPTTEVT 1107
Query: 199 HLENEESKETGESSEEKSHLENEESKETGESSEE---KSHLENEENKDEEKSKQENEEIK 255
+E + G + H + + + +EE K ++N E E + ++ K
Sbjct: 1108 KEPVDEITQFGGEEVPQGHKDEFDPNLPIDGTEEVPGKPGIKNPET-GEVVTPPVDDVTK 1166
Query: 256 DGEKIQQENEENKDEEKSQQENEENKDEEKSQQENELKKNEGGEKET------GEITEEK 309
G K E E K+E + + + E + +K E GEK T +T EK
Sbjct: 1167 HGPKAG-EPEVTKEEIPYETKRVLDPTMEPGSPDKVAQKGENGEKTTTTPTTINPLTGEK 1225
Query: 310 SKQENEETSETNSKDKENEESNQNGSDAKEQVGENHEQDSKQG-TEETNGTEGGEKEEHD 368
E E T+E +K+ +E N E + + +G T+ G +G + E
Sbjct: 1226 VG-EGEPTTEV-TKEPIDEIVNYAPEIIPHGTREEIDPNLPEGETKVIPGKDGLKDPETG 1283
Query: 369 KIKEDTSSDNQVQDGEKNNEAREENYSGDNASSAVVDNKSQESSNK---TEEQFDKKEKN 425
+I E+ D + G K++ + + D+ S A D+ + S+ ++ D +
Sbjct: 1284 EIIEEPQ-DEVIIHGAKDDSDADSDSDADSDSDADSDSDADSDSDADSDSDSDSDSDSDS 1342
Query: 426 EFELESQKNSNETTES-TDSTITQNSQGNESEKDQAQTENDTPKGSASESDEQKQEQEQN 484
+ + +S +S+ +++ +DS +S + A +++D+ S S+SD +
Sbjct: 1343 DSDADSDSDSDSDSDADSDSDADSDSDADSDSDSDADSDSDSDADSDSDSDSDSDADSDS 1402
Query: 485 NTTKDDVQTTDTSSQNGNDTTEKQNETSEDANSKKEDSSALNTTPNNEDSKSGVAGDQAD 544
++ D +D+ + + +D+ + S+ + D+ + + ++ D+ S D
Sbjct: 1403 DSDSDSDADSDSDADSDSDSDSDSDADSDSDSDSDSDADSDSDADSDSDADSDSDADSDS 1462
Query: 545 STTTTSSSETQDGNTNHGEYKDTTNENPEKNSGQEGTQESGSSSNTFDNKDAASNKVQLT 604
+ + S +++ + + ++ + + +S + +S S S++ + DA S+
Sbjct: 1463 DSDSDSDADSDSDADSDSDADSDSDADSDSDSDSDSDADSDSDSDSDSDSDADSD----- 1517
Query: 605 TTSDTSSEQKKDESSSAESKSESSQNDNANSGQSNTTSDESANDNKDSSQVTTSSENSAE 664
+ +D+ S+ D S A+S S++ + +A+S S+ SD ++ + DS + S+ ++
Sbjct: 1518 SDADSDSDSDADSDSDADSDSDADGDSDADS-DSDADSDSDSDSDSDSD---SDSDADSD 1573
Query: 665 GNSNTENNSDENQNDSKNNENTNDSGNTSNDANVN 699
+S++++++D + ND + N + +T NDA N
Sbjct: 1574 SDSDSDSDADRDHNDKTDKPNNKELPDTGNDAQNN 1608
Score = 109 bits (273), Expect = 2e-23
Identities = 167/799 (20%), Positives = 326/799 (39%), Gaps = 89/799 (11%)
Query: 43 EQKASYGASTKTGNE-VVKLGRKDLKPRVEETSVIDARHKEDEEEADELDNKHDEQTKLD 101
E+K + K G E V + G+ K T++ ++ E + + ++
Sbjct: 800 EKKREFNPDLKPGEEKVTQEGQTGEKTTTTPTTINPLTGEKVGEGEPTTEVTKEPVDEIT 859
Query: 102 DVNGVEDNSEHKEDSVEQ------ESEESSQNAKTDLEGEQHTEKVDEENDNAENKENES 155
G E HK++ E K GE T VD+ +
Sbjct: 860 QFGGEEVPQGHKDEFDPNLPIDGTEEVPGKPGIKNPETGEVVTPPVDDVTKHGPKAGEPE 919
Query: 156 VEKENEEIKKEVEDTETGESIEEKSHLENEESKET-----------------GEISEEKS 198
V KE +K+ E + EEK E + ++T GE + E +
Sbjct: 920 VTKEEIPFEKKREFNPDLKPGEEKVTQEGQTGEKTTTTPTTINPLTGEKVGEGEPTTEVT 979
Query: 199 HLENEESKETGESSEEKSHLENEESKETGESSEE---KSHLENEENKDEEKSKQENEEIK 255
+E + G + H + + + +EE K ++N E E + ++ K
Sbjct: 980 KEPVDEITQFGGEEVPQGHKDEFDPNLPIDGTEEVPGKPGIKNPET-GEVVTPPVDDVTK 1038
Query: 256 DGEKIQQENEENKDEEKSQQENEENKDEEKSQQENELKKNEGGEKET------GEITEEK 309
G K E E K+E +++ E N D K +E ++ + GEK T +T EK
Sbjct: 1039 HGPKAG-EPEVTKEEIPFEKKREFNPDL-KPGEEKVTQEGQTGEKTTTTPTTINPLTGEK 1096
Query: 310 SKQENEETSETNSKDKENEESNQNGSDAKEQVGENHEQDSK---QGTEETNGTEGGEKEE 366
E E T+E +K+ +E + G + + G E D GTEE G G + E
Sbjct: 1097 VG-EGEPTTEV-TKEPVDEITQFGGEEVPQ--GHKDEFDPNLPIDGTEEVPGKPGIKNPE 1152
Query: 367 HDKIKEDTSSDNQVQDGEKNNEAREENYSGDNASSAVVDNKSQESS-NKTEEQFDKKEKN 425
++ D+ + G K E + V+D + S +K ++ + EK
Sbjct: 1153 TGEVVTPPV-DDVTKHGPKAGEPEVTKEEIPYETKRVLDPTMEPGSPDKVAQKGENGEKT 1211
Query: 426 EFELESQKNSNETTESTDSTITQNSQGNESEKDQAQTE----------NDTPKGSASESD 475
TT +T + +T G + E P G+ E D
Sbjct: 1212 T-----------TTPTTINPLTGEKVGEGEPTTEVTKEPIDEIVNYAPEIIPHGTREEID 1260
Query: 476 EQKQEQEQNNTT-KDDVQTTDTSSQNGNDTTEKQNET----SEDANSKKEDSSALNTTPN 530
E E KD ++ +T G E Q+E ++D + DS A + +
Sbjct: 1261 PNLPEGETKVIPGKDGLKDPET----GEIIEEPQDEVIIHGAKDDSDADSDSDADSDSDA 1316
Query: 531 NEDSKSGVAGDQADSTTTTSSSETQDGNTNHGEYKDTTNENPEKNSGQEGTQESGSSSNT 590
+ DS + D ADS + + S D +++ D+ +++ + +S + +S + S++
Sbjct: 1317 DSDSDADSDSD-ADSDSDSDSDSDSDSDSDADSDSDSDSDS-DADSDSDADSDSDADSDS 1374
Query: 591 FDNKDAASNKVQLTTTSDTSSEQKKDESSSAESKSESSQNDNANS---GQSNTTSDESAN 647
+ D+ S+ + SD+ S+ D S ++S S++ + +A+S S++ +D ++
Sbjct: 1375 DSDADSDSDS-DADSDSDSDSDSDADSDSDSDSDSDADSDSDADSDSDSDSDSDADSDSD 1433
Query: 648 DNKDSSQVTTSSENSAEGNSNTENNSDENQNDSKNNENTNDSGNTSNDANVNENQNENAA 707
+ DS S++ A+ +S+ +++SD + +DS ++ +++ ++ D++ + + + +A
Sbjct: 1434 SDSDSD---ADSDSDADSDSDADSDSDAD-SDSDSDSDSDADSDSDADSDSDADSDSDAD 1489
Query: 708 QTKTSENEGDAQNESVESKKENNESAHKDVDNNSNSNDQGSSDTSVTQD---DKESRVDL 764
S+++ DA ++S +S +++ A D D +S+S+ SD+ D D +S D
Sbjct: 1490 SDSDSDSDSDADSDS-DSDSDSDSDADSDSDADSDSDSDADSDSDADSDSDADGDSDADS 1548
Query: 765 GTLPESNGESHHNDVSSAE 783
+ +S+ +S + S ++
Sbjct: 1549 DSDADSDSDSDSDSDSDSD 1567
Score = 100 bits (249), Expect = 1e-20
Identities = 100/563 (17%), Positives = 216/563 (37%), Gaps = 56/563 (9%)
Query: 114 EDSVEQESEESSQNAKTDL-----------EGEQHTEKVDEENDNAENKENESVEKENEE 162
E+ V QE + + T EGE TE E D E V + +
Sbjct: 1069 EEKVTQEGQTGEKTTTTPTTINPLTGEKVGEGEPTTEVTKEPVDEITQFGGEEVPQGH-- 1126
Query: 163 IKKEVEDTETGESIEEKSHLENEESKETGEISEEKSHLENEESKETGESSEEKSHLENEE 222
K E + + EE ++ ETGE+ + + GE K + E
Sbjct: 1127 -KDEFDPNLPIDGTEEVPGKPGIKNPETGEVVTPPVDDVTKHGPKAGEPEVTKEEIPYET 1185
Query: 223 SK------ETGESSEEKSHLENEENKDEEKSKQE---NEEIKDGEKIQQENEENKDE--- 270
+ E G + EN E + E++ +GE + +E DE
Sbjct: 1186 KRVLDPTMEPGSPDKVAQKGENGEKTTTTPTTINPLTGEKVGEGEPTTEVTKEPIDEIVN 1245
Query: 271 ---EKSQQENEENKDEEKSQQENELKKNEGGEK--ETGEITEEKSKQ-------ENEETS 318
E E D + E ++ + G K ETGEI EE + ++ +
Sbjct: 1246 YAPEIIPHGTREEIDPNLPEGETKVIPGKDGLKDPETGEIIEEPQDEVIIHGAKDDSDAD 1305
Query: 319 ETNSKDKENEESNQNGSDAKEQVGENHEQDSKQGTEETNGTEGGEKEEHDKIKEDTSSDN 378
+ D +++ + + +D+ + + DS ++ + + + D + S +
Sbjct: 1306 SDSDADSDSDADSDSDADSDSDADSDSDSDSDSDSDSDSDADSDSDSDSDSDADSDSDAD 1365
Query: 379 QVQDGEKNNEAREENYSGDNASSAVVDNKSQESSNKTEEQFDKKEKNEFELESQKNSNET 438
D + ++++ ++ S +A S + ++ + ++ D ++ + +S +S+
Sbjct: 1366 SDSDADSDSDSDADSDSDSDADSDSDSDSDSDADSDSDSDSDSDADSDSDADSDSDSDSD 1425
Query: 439 TESTDSTITQNSQGNESEKDQAQTENDTPKGSASESDEQKQEQEQNNTTKDDVQTTDTSS 498
+++ + + + +S+ D A +++D S ++SD ++ D +D S
Sbjct: 1426 SDADSDSDSDSDSDADSDSD-ADSDSDADSDSDADSDSDSDSDSDADSDSDADSDSDADS 1484
Query: 499 QNGNDTTEKQNETSEDANSKKEDSSALNTTPNNEDSKSGVAGDQADSTTTTSSSETQDGN 558
+ D+ + +++ DA+S + S ++ +++ + ADS + S DG+
Sbjct: 1485 DSDADS-DSDSDSDSDADSDSDSDSDSDSDADSDSDADSDSDSDADSDSDADSDSDADGD 1543
Query: 559 TNHGEYKDTTNENPEKNSGQEGTQESGSSSNTFDNKDAASNKVQLTTTSDTSSEQKKDES 618
++ + +S + +S S S++ + DA S+ + SD+ S+ +D +
Sbjct: 1544 SD-----------ADSDSDADSDSDSDSDSDSDSDSDADSD-----SDSDSDSDADRDHN 1587
Query: 619 SSAESKSESSQNDNANSGQSNTT 641
+ + D N Q+N T
Sbjct: 1588 DKTDKPNNKELPDTGNDAQNNGT 1610
Score = 95.1 bits (235), Expect = 6e-19
Identities = 171/815 (20%), Positives = 317/815 (37%), Gaps = 102/815 (12%)
Query: 44 QKASYGASTKTGNEVVKLGRKDLKPRVEETSVIDARHKED--EEEADELDNKHDEQTKLD 101
QK G T T V D+ R E T+ + ++ +E+ H ++
Sbjct: 690 QKGEDGEKTTTTPTKVDPDTGDVVERGEPTTEVTKNPVDEIVHFTPEEVPQGHKDEF--- 746
Query: 102 DVNGVEDNSEHKEDSVEQESEESSQNAKTDLEGEQHTEKVDEENDNAENKENESVEKENE 161
D N D +E E + +N +T GE T VD+ + V KE
Sbjct: 747 DPNLPIDGTE------EVPGKPGIKNPET---GEVVTPPVDDVTKHGPKAGEPEVTKEEI 797
Query: 162 EIKKEVEDTETGESIEEKSHLENEESKET-----------------GEISEEKSHLENEE 204
+K+ E + EEK E + ++T GE + E + +E
Sbjct: 798 PFEKKREFNPDLKPGEEKVTQEGQTGEKTTTTPTTINPLTGEKVGEGEPTTEVTKEPVDE 857
Query: 205 SKETGESSEEKSHLENEESKETGESSEE---KSHLENEENKDEEKSKQENEEIKDGEKIQ 261
+ G + H + + + +EE K ++N E E + ++ K G K
Sbjct: 858 ITQFGGEEVPQGHKDEFDPNLPIDGTEEVPGKPGIKNPET-GEVVTPPVDDVTKHGPK-A 915
Query: 262 QENEENKDEEKSQQENEENKDEEKSQQENELKKNEGGEKET------GEITEEKSKQENE 315
E E K+E +++ E N D K +E ++ + GEK T +T EK E E
Sbjct: 916 GEPEVTKEEIPFEKKREFNPD-LKPGEEKVTQEGQTGEKTTTTPTTINPLTGEK-VGEGE 973
Query: 316 ETSETNSKDKENEESNQNGSDAKEQVGENHEQDSK-----QGTEETNGTEGGEKEEHDKI 370
T+E +K+ +E + G E+V + H+ + GTEE G G + E ++
Sbjct: 974 PTTEV-TKEPVDEITQFGG----EEVPQGHKDEFDPNLPIDGTEEVPGKPGIKNPETGEV 1028
Query: 371 KEDTSSDNQVQDGEK--NNEAREENYSGDNASSAVVDNKSQESSNKTEEQFDKKEK---- 424
D+ + G K E +E + D K E E Q +K
Sbjct: 1029 -VTPPVDDVTKHGPKAGEPEVTKEEIPFEKKREFNPDLKPGEEKVTQEGQTGEKTTTTPT 1087
Query: 425 --NEFELESQKNSNETTESTDSTITQNSQGNESEKDQAQTENDTPKGSASESDEQKQEQE 482
N E TTE T + + +Q E Q + P ++E +
Sbjct: 1088 TINPLTGEKVGEGEPTTEVTKEPVDEITQFGGEEVPQGHKDEFDPNLPIDGTEEVPGKPG 1147
Query: 483 QNNTTKDDVQT--TDTSSQNGNDTTEKQ--------------NETSEDAN-----SKKED 521
N +V T D +++G E + + T E + K E+
Sbjct: 1148 IKNPETGEVVTPPVDDVTKHGPKAGEPEVTKEEIPYETKRVLDPTMEPGSPDKVAQKGEN 1207
Query: 522 SSALNTTPNNEDSKSGVAGDQADSTTTTSSSETQDGNTN-------HGEYKDTTNENPEK 574
TTP + +G + + TT + E D N HG ++ PE
Sbjct: 1208 GEKTTTTPTTINPLTGEKVGEGEPTTEV-TKEPIDEIVNYAPEIIPHGTREEIDPNLPEG 1266
Query: 575 NS----GQEGTQESGSSSNTFDNKDAASNKVQLTTTSDTSSEQKKDESSSAESKSESSQN 630
+ G++G ++ + + +D SD S+ D S A+S S++ +
Sbjct: 1267 ETKVIPGKDGLKDPETGEIIEEPQDEVIIH-GAKDDSDADSDSDADSDSDADSDSDADSD 1325
Query: 631 DNANSGQSNTTSDESANDNKDSSQVTTSSENSAEGNSNTENNSDENQNDSKNNENTNDSG 690
+A+S + + +S +D+ S + S++ A+ +S+ +++SD DS ++ + +
Sbjct: 1326 SDADSDSDSDSDSDSDSDSDADSDSDSDSDSDADSDSDADSDSDA---DSDSDSDADSDS 1382
Query: 691 NTSNDANVNENQNENAAQTKTSENEGDAQNES-VESKKENNESAHKDVDNNSNSNDQGSS 749
++ D++ + + + +A S+++ DA ++S +S +++ + D D++S+S+ S
Sbjct: 1383 DSDADSDSDSDSDSDADSDSDSDSDSDADSDSDADSDSDSDSDSDADSDSDSDSDSDADS 1442
Query: 750 DTSVTQD-DKESRVDLGTLPESNGESHHNDVSSAE 783
D+ D D +S D + +S+ +S + S A+
Sbjct: 1443 DSDADSDSDADSDSDADSDSDSDSDSDADSDSDAD 1477
Score = 80.9 bits (198), Expect = 1e-14
Identities = 125/556 (22%), Positives = 210/556 (37%), Gaps = 70/556 (12%)
Query: 83 DEEEADELDNKHDEQTKLDDVNGVEDNSEHKEDSVEQESEESSQNAKTDLEGEQHTEKVD 142
D+ EA E +N +Q D + V+ N + ++EQ S S+++ D+ + K
Sbjct: 44 DQAEAAE-NNTTQKQDDSSDASKVKGNVQ----TIEQSSANSNES---DIPEQVDVTKDT 95
Query: 143 EENDNAENKENESVEKENEEIKKEVEDTETGES--IEEKSHLENEESKETGEISEEKSHL 200
E + E K N + + EE E T E+ E +E EE+ + E + +
Sbjct: 96 TEQASTEEKANTTEQASTEEKADTTEQATTEEAPKAEGTDKVETEEAPKAEETDKATTE- 154
Query: 201 ENEESKETGESSEEKSHLENEESKETGES--SEEKSHLENEEN-KDEEKSKQENEEIKDG 257
E +++ET +++EE E + T E+ +EE S EE K EE SK EE
Sbjct: 155 EAPKAEETDKATEEAPKTEETDKATTEEAPAAEETSKAATEEAPKAEETSKAATEEAPKA 214
Query: 258 EKIQQENEEN--KDEEKSQQENEENKDEE---KSQQENELKKNEGGEKETGEI--TEEKS 310
E+ ++ E K EE + E EE E K+ E K E + ET E EE +
Sbjct: 215 EETEKTATEEAPKTEETDKVETEEAPKAEETSKAATEKAPKAEETNKVETEEAPAAEETN 274
Query: 311 KQENEETSETNSKDKENEESNQNGSDAKEQVGENHEQDSKQGTEETNGTEGGEKEEHDKI 370
K EET + ++ + Q + QV + +D + +E T EK E +K+
Sbjct: 275 KAATEETPAVEDTNAKSNSNAQPSETERTQVVDTVAKDLYKKSEVTE----AEKAEIEKV 330
Query: 371 --KEDTSSDNQVQDGEKNNEAREENYSGDNASSAVVDNKSQESSNKTEEQFDKKEKNEFE 428
K+ ++ N+ +E +E + +NA ++ T + +
Sbjct: 331 LPKDISNLSNEEIKKIALSEVLKETANKENAQPRATFRSVSSNARTTNVNY-----SATA 385
Query: 429 LESQKNSNETTESTDSTITQNSQGNESEKDQAQTE------------NDTPKGSASESDE 476
L + T + T + +++ K++ E N KG+ +D+
Sbjct: 386 LRAAAQDTVTKKGTGNFTAHGDIIHKTYKEEFPNEGTLTAFNTNFNPNTGTKGALEYNDK 445
Query: 477 -----------QKQEQEQNNTTKDDVQTTDTSSQNGNDTTEKQNETSEDANSKKEDSSAL 525
Q NTT D + NG D Q D +
Sbjct: 446 IDFNKDFTITVPVANNNQGNTTGADGWGFMFTQGNGQDFL-NQGGILRDKGMANASGFKI 504
Query: 526 NTTPNNEDSKSGVAGDQADSTTTTSSSETQDGNTNHGEYKDTTNENPEKNSGQEGTQESG 585
+T NN + K D+ D+ T + S+ +G + KN T + G
Sbjct: 505 DTAYNNVNGKV----DKLDADKTNNLSQIGAAKVGYGTF--------VKNGADGVTNQVG 552
Query: 586 SSSNTFDNKDAASNKV 601
N + KD NK+
Sbjct: 553 --QNALNTKDKPVNKI 566
Score = 76.6 bits (187), Expect = 2e-13
Identities = 101/439 (23%), Positives = 167/439 (38%), Gaps = 47/439 (10%)
Query: 209 GESSEEKSHLENEESKETGESSEEKSHLENEENKDEEKSKQENEEIKDGEKIQQENEENK 268
G ++++ EN +++ +SS+ N + ++ + +I + + ++ E
Sbjct: 40 GVANDQAEAAENNTTQKQDDSSDASKVKGNVQTIEQSSANSNESDIPEQVDVTKDTTEQA 99
Query: 269 DEEKSQQENEENKDEEKSQ-----QENELKKNEGGEK-ETGEI--TEEKSKQENEETSET 320
E+ E+ EEK+ E K EG +K ET E EE K EE +
Sbjct: 100 STEEKANTTEQASTEEKADTTEQATTEEAPKAEGTDKVETEEAPKAEETDKATTEEAPKA 159
Query: 321 NSKDKENEES--NQNGSDAKEQVGENHEQDSKQGTEETNGTEGGEK---EEHDKIK--ED 373
DK EE+ + A + E+ SK TEE E K EE K + E
Sbjct: 160 EETDKATEEAPKTEETDKATTEEAPAAEETSKAATEEAPKAEETSKAATEEAPKAEETEK 219
Query: 374 TSSDNQVQDGEKNNEAREENYSGDNASSAVVDNKSQ-ESSNKTEEQFDKKEKNEFELESQ 432
T+++ + E + EE + S A + + E +NK E + E E ++
Sbjct: 220 TATEEAPKTEETDKVETEEAPKAEETSKAATEKAPKAEETNKVETE----EAPAAEETNK 275
Query: 433 KNSNETTESTDSTITQNSQGNESEKDQAQTENDTPKGSASESDEQKQEQ-EQNNTTKDDV 491
+ ET D+ NS SE ++ Q + K +S+ + E+ E D+
Sbjct: 276 AATEETPAVEDTNAKSNSNAQPSETERTQVVDTVAKDLYKKSEVTEAEKAEIEKVLPKDI 335
Query: 492 QTTDTSSQNGNDTTEKQNETSEDANSK-----KEDSSALNTTPNNEDSKSGVAGDQADST 546
+E ET+ N++ + SS TT N + + A Q T
Sbjct: 336 SNLSNEEIKKIALSEVLKETANKENAQPRATFRSVSSNARTTNVNYSATALRAAAQDTVT 395
Query: 547 TTTSSSETQDGNTNHGEYKD-----------TTNENPEKNSGQEGTQESGSSSNTFDNKD 595
+ + T G+ H YK+ TN NP N+G +G E + NKD
Sbjct: 396 KKGTGNFTAHGDIIHKTYKEEFPNEGTLTAFNTNFNP--NTGTKGALEYNDKIDF--NKD 451
Query: 596 ------AASNKVQLTTTSD 608
A+N TT +D
Sbjct: 452 FTITVPVANNNQGNTTGAD 470
Score = 64.7 bits (156), Expect = 9e-10
Identities = 69/349 (19%), Positives = 132/349 (37%), Gaps = 40/349 (11%)
Query: 376 SDNQVQDGEKNNEAREENYSGDNASSAVVDNKSQESSNKTEEQFDKKEKNEFELESQKNS 435
+++Q + E N ++++ S + V Q S+N E + + ++
Sbjct: 42 ANDQAEAAENNTTQKQDDSSDASKVKGNVQTIEQSSANSNESDIPE----QVDVTKDTTE 97
Query: 436 NETTESTDSTITQNSQGNESEKDQAQTENDTPKGSAS---ESDEQKQEQEQNNTTKDDV- 491
+TE +T Q S +++ + T + PK + E++E + +E + T ++
Sbjct: 98 QASTEEKANTTEQASTEEKADTTEQATTEEAPKAEGTDKVETEEAPKAEETDKATTEEAP 157
Query: 492 --QTTDTSSQNGNDTTEKQNETSEDANSKKEDSSALNTTPNNEDSKSGVAGDQADSTTTT 549
+ TD +++ T E T+E+A + +E S A + S A ++A T
Sbjct: 158 KAEETDKATEEAPKTEETDKATTEEAPAAEETSKAATEEAPKAEETSKAATEEAPKAEET 217
Query: 550 SSSETQDGNTNHGEYKDTTNENPEKNSGQEGTQESGSSSNTFDNKDAASNKVQLTTTSDT 609
+ T++ K T E P+ +E+ ++ K +NKV+ T +
Sbjct: 218 EKTATEEAPKTEETDKVETEEAPK-------AEETSKAATEKAPKAEETNKVE-TEEAPA 269
Query: 610 SSEQKK--DESSSAESKSESSQNDNANSGQSNTTS--DESANDNKDSSQVTTSSENSAEG 665
+ E K E + A + + N NA ++ T D A D S+VT + + E
Sbjct: 270 AEETNKAATEETPAVEDTNAKSNSNAQPSETERTQVVDTVAKDLYKKSEVTEAEKAEIE- 328
Query: 666 NSNTENNSDENQNDSKNNENTNDSGNTSNDANVNENQNENAAQTKTSEN 714
D N SN+ +E +T EN
Sbjct: 329 -----------------KVLPKDISNLSNEEIKKIALSEVLKETANKEN 360
Score = 61.2 bits (147), Expect = 1e-08
Identities = 48/270 (17%), Positives = 110/270 (39%), Gaps = 7/270 (2%)
Query: 495 DTSSQNGNDTTEKQNETSEDANSKKEDSSALNTTPNNEDSKSGVAGDQADSTTTTSSSET 554
D + N+TT+KQ+++S+ + K + ++ N+ +S D TT +S+E
Sbjct: 44 DQAEAAENNTTQKQDDSSDASKVKGNVQTIEQSSANSNESDIPEQVDVTKDTTEQASTEE 103
Query: 555 QDGNTNHGEYKDTTNENPEKNSGQEGTQESGSSSNTFDNKDAASNKVQLTTTSDTSSEQK 614
+ T + + E + Q T+E+ + T + + K + T + T K
Sbjct: 104 KANTT-----EQASTEEKADTTEQATTEEAPKAEGTDKVETEEAPKAEETDKATTEEAPK 158
Query: 615 KDESSSA-ESKSESSQNDNANSGQSNTTSDESANDNKDSSQVTTSSENSAEGNSNTENNS 673
+E+ A E ++ + D A + ++ + S +++ + +S+ + E E
Sbjct: 159 AEETDKATEEAPKTEETDKATTEEAPAAEETSKAATEEAPKAEETSKAATEEAPKAEETE 218
Query: 674 DENQNDSKNNENTNDSGNTSNDANVNENQNENAAQTKTSENEGDAQNESVESKKENNESA 733
++ E T D T E + +E + E + +E N++A
Sbjct: 219 KTATEEAPKTEET-DKVETEEAPKAEETSKAATEKAPKAEETNKVETEEAPAAEETNKAA 277
Query: 734 HKDVDNNSNSNDQGSSDTSVTQDDKESRVD 763
++ ++N + +S+ ++ ++ VD
Sbjct: 278 TEETPAVEDTNAKSNSNAQPSETERTQVVD 307
Score = 60.8 bits (146), Expect = 1e-08
Identities = 58/315 (18%), Positives = 125/315 (39%), Gaps = 38/315 (12%)
Query: 449 NSQGNESEKDQAQTENDTPKGSASESDEQKQEQEQNNTTKDDVQ-----TTDTSSQNGND 503
N Q +E + Q ++D+ S + + Q EQ N+ + D+ T DT+ Q +
Sbjct: 43 NDQAEAAENNTTQKQDDSSDASKVKGNVQTIEQSSANSNESDIPEQVDVTKDTTEQASTE 102
Query: 504 ---------TTEKQNETSEDANSKKEDSSALNTTPNNEDSKSGVAGDQADSTTTTSSSET 554
+TE++ +T+E A +++ + E++ D+A + + ET
Sbjct: 103 EKANTTEQASTEEKADTTEQATTEEAPKAEGTDKVETEEAPKAEETDKATTEEAPKAEET 162
Query: 555 QDGNTNHGEYKDTTNENPEKNSGQEGTQESGSSSNTFDNKDAASNKVQLTTTSDTSSEQK 614
T E P+ + T E ++ ++ + + ++ +S+
Sbjct: 163 D----------KATEEAPKTEETDKATTEEAPAA-----EETSKAATEEAPKAEETSKAA 207
Query: 615 KDESSSAESKSESSQNDNANSGQSNTTSDESANDNKDSSQVTTSSENSAEGNSNTENNSD 674
+E+ AE +++ + + +++ E A +++S+ T AE + E ++
Sbjct: 208 TEEAPKAEETEKTATEEAPKTEETDKVETEEAPKAEETSKAATEKAPKAEETNKVE--TE 265
Query: 675 ENQNDSKNNENTNDSGNTSNDANVNENQNENAAQTK------TSENEGDAQNESVESKKE 728
E + N+ + D N N N ++T+ T + ++E E++K
Sbjct: 266 EAPAAEETNKAATEETPAVEDTNAKSNSNAQPSETERTQVVDTVAKDLYKKSEVTEAEKA 325
Query: 729 NNESA-HKDVDNNSN 742
E KD+ N SN
Sbjct: 326 EIEKVLPKDISNLSN 340
Score = 58.9 bits (141), Expect = 5e-08
Identities = 91/461 (19%), Positives = 176/461 (37%), Gaps = 60/461 (13%)
Query: 313 ENEETSETNSKDKENEESNQNGSDAKEQVGENHEQDSKQGTEETNGTEGGEKEEHDKIKE 372
+ E +E N+ K+++ S+ S K V + EQ S N E E+ D K+
Sbjct: 44 DQAEAAENNTTQKQDDSSD--ASKVKGNV-QTIEQSS------ANSNESDIPEQVDVTKD 94
Query: 373 DTSSDNQVQDGEKNNEAREENYSGDNASSAVVDNKSQESSNKTEEQFDKKE-KNEFELES 431
T Q EK N + A + K+ + T E+ K E ++ E E
Sbjct: 95 TTE---QASTEEKANTTEQ----------ASTEEKADTTEQATTEEAPKAEGTDKVETEE 141
Query: 432 QKNSNETTESTDSTITQNSQGNESEKDQAQTENDTPKGSASESDEQKQEQEQNNTTKDDV 491
+ ET ++T + + +++ ++ +TE +T K + E+ ++ +
Sbjct: 142 APKAEETDKATTEEAPKAEETDKATEEAPKTE-ETDKATTEEAPAAEETSKAATEEAPKA 200
Query: 492 QTTDTSSQNGNDTTEKQNETSEDANSKKEDSSALNT--TPNNEDSKSGVAGDQADSTTTT 549
+ T ++ E+ +T+ + K E++ + T P E++ S A ++A T
Sbjct: 201 EETSKAATEEAPKAEETEKTATEEAPKTEETDKVETEEAPKAEET-SKAATEKAPKAEET 259
Query: 550 SSSETQDGNTNHGEYKDTTNENPEKNSGQEGTQESGSSSNTFDNKDAASNKVQLTTTSDT 609
+ ET++ K T E P + +N N +A ++ + T DT
Sbjct: 260 NKVETEEAPAAEETNKAATEETP-----------AVEDTNAKSNSNAQPSETERTQVVDT 308
Query: 610 SSEQ--KKDESSSAESKS---------ESSQNDNANSGQSNTTSDESANDNKDSSQVTTS 658
++ KK E + AE + N+ + E+AN + T
Sbjct: 309 VAKDLYKKSEVTEAEKAEIEKVLPKDISNLSNEEIKKIALSEVLKETANKENAQPRATFR 368
Query: 659 SENSAEGNSNTENNSDENQNDSKNNENTNDSGN-TSNDANVNENQNENAAQ--TKTSENE 715
S +S +N ++ + +++ +GN T++ +++ E T T+ N
Sbjct: 369 SVSSNARTTNVNYSATALRAAAQDTVTKKGTGNFTAHGDIIHKTYKEEFPNEGTLTAFNT 428
Query: 716 GDAQNESVESKKENNESA--HKD------VDNNSNSNDQGS 748
N + E N+ +KD V NN+ N G+
Sbjct: 429 NFNPNTGTKGALEYNDKIDFNKDFTITVPVANNNQGNTTGA 469
Score = 49.3 bits (116), Expect = 4e-05
Identities = 34/159 (21%), Positives = 70/159 (43%), Gaps = 5/159 (3%)
Query: 630 NDNANSGQSNTT--SDESANDNKDSSQVTTSSENSAEGNSNTENNSDENQNDSKNNENTN 687
ND A + ++NTT D+S++ +K V T ++SA N + + D+ +T
Sbjct: 43 NDQAEAAENNTTQKQDDSSDASKVKGNVQTIEQSSANSNESDIPEQVDVTKDTTEQASTE 102
Query: 688 DSGNTSNDANVNE--NQNENAAQTKTSENEGDAQNESVES-KKENNESAHKDVDNNSNSN 744
+ NT+ A+ E + E A + + EG + E+ E+ K E + A + +
Sbjct: 103 EKANTTEQASTEEKADTTEQATTEEAPKAEGTDKVETEEAPKAEETDKATTEEAPKAEET 162
Query: 745 DQGSSDTSVTQDDKESRVDLGTLPESNGESHHNDVSSAE 783
D+ + + T++ ++ + E ++ + AE
Sbjct: 163 DKATEEAPKTEETDKATTEEAPAAEETSKAATEEAPKAE 201
Score = 33.1 bits (74), Expect = 2.9
Identities = 19/127 (14%), Positives = 52/127 (39%), Gaps = 3/127 (2%)
Query: 77 DARHKEDEEEADELDNKHDEQTKLDDVNGVEDNSEHKEDSVEQESEESSQNAKTDLEGEQ 136
D+ D + + D D + D + + +S+ DS +S ++ +D +G+
Sbjct: 1485 DSDADSDSDSDSDSDADSDSDSDSDSDSDADSDSDADSDSDSDADSDSDADSDSDADGDS 1544
Query: 137 HTEK---VDEENDNAENKENESVEKENEEIKKEVEDTETGESIEEKSHLENEESKETGEI 193
+ D ++D+ + +++S + + + + + ++ N+E +TG
Sbjct: 1545 DADSDSDADSDSDSDSDSDSDSDSDADSDSDSDSDSDADRDHNDKTDKPNNKELPDTGND 1604
Query: 194 SEEKSHL 200
++ L
Sbjct: 1605 AQNNGTL 1611
>IF2P_HUMAN (O60841) Eukaryotic translation initiation factor 5B
(eIF-5B) (Translation initiation factor IF-2)
Length = 1220
Score = 121 bits (303), Expect = 8e-27
Identities = 130/631 (20%), Positives = 283/631 (44%), Gaps = 81/631 (12%)
Query: 64 KDLKPRVEETSVIDARHKEDEEEADELDNKHDEQTKLDDVNGVEDNSEHKEDSVEQESEE 123
K+ +P+ + + K+D +E D L K E+ L+ G++ + E + +EE
Sbjct: 33 KEQEPQKSKGKKKKEKKKQDFDEDDIL--KELEELSLE-AQGIKADRETVAVKPTENNEE 89
Query: 124 SSQNAKTDLEGEQHTEKVDEENDNAENKENESVEKENEEIKKEV----EDTETGESIEEK 179
+ +G++ ++ ++ND+ E ++ +S K+ + K E+ +D + + +K
Sbjct: 90 EFTSKDKKKKGQKGKKQSFDDNDSEELEDKDSKSKKTAKPKVEMYSGSDDDDDFNKLPKK 149
Query: 180 SHLENEESKETGEISEE-----KSHLENEESKETGESSEEKSH-LENEESKETGESSEEK 233
+ + ++S + + SEE K E +GES +E L++ + ++ + ++
Sbjct: 150 AKGKAQKSNKKWDGSEEDEDNSKKIKERSRINSSGESGDESDEFLQSRKGQKKNQKNKPG 209
Query: 234 SHLENEENKDEEKSKQENEEIKDGEKIQQENEENKDEEKSQQENEENKDEEKSQQENELK 293
++E+ D+ K + K EK ++E ++ +DEEK++ + K+E ++ ++++ K
Sbjct: 210 PNIESGNEDDDASFKIKTVAQKKAEKKERERKK-RDEEKAKLRKLKEKEELETGKKDQSK 268
Query: 294 KNEGGEKETGEITEEKSKQE------NEETSETNSKDKENEESNQNGSDAKEQVGENHEQ 347
+ E K E + K + +EE +ET + +++ E ++ D K++ GE E+
Sbjct: 269 QKESQRKFEEETVKSKVTVDTGVIPASEEKAETPTAAEDDNEGDKKKKDKKKKKGEKEEK 328
Query: 348 DSKQGTEETNGTEGGEKEEHDKIKEDTSSDNQVQDGEKNNEAREENYSGDNASSAVVDNK 407
+ ++ + T +E K+KE+ + Q ++ E+ + EE + + K
Sbjct: 329 EKEKKKGPSKATVKAMQEALAKLKEE--EERQKREEEERIKRLEELEAKRKEEERLEQEK 386
Query: 408 SQESSNKTEEQFDK-KEKNEFELESQKNSNETTESTDSTITQNSQGNESEKDQAQTENDT 466
+ K +E+ ++ K++ + +SQ+ + E+T + +QG E +++
Sbjct: 387 RERKKQKEKERKERLKKEGKLLTKSQREARARAEATLKLL--QAQGVE-----VPSKDSL 439
Query: 467 PKGSASESDEQKQEQEQNNTTKDDVQTTDTSSQNGNDTTEKQNETSEDANSKKEDSSALN 526
PK D+++++ Q +K+ ++ + + E E +KE++
Sbjct: 440 PKKRPIYEDKKRKKIPQQLESKEVSESMELCAAV---------EVMEQGVPEKEETPP-P 489
Query: 527 TTPNNEDSKSGVAGDQADSTTTTSSSETQDGNTNHGEYKDTTNENPEKNSGQEGTQESGS 586
P E+ D ++ + +E +GNT H E K ENPE+ +E +E
Sbjct: 490 VEPEEEEDTEDAGLDDWEAMASDEETEKVEGNTVHIEVK----ENPEEEEEEEEEEE--- 542
Query: 587 SSNTFDNKDAASNKVQLTTTSDTSSEQKKDESSSAESKSESSQNDNANSGQSNTTSDESA 646
D SE++++E E +SE S+ D DE
Sbjct: 543 --------------------EDEESEEEEEE----EGESEGSEGDE---------EDEKV 569
Query: 647 NDNKDSSQVTTSSENSAEGNSNTENNSDENQ 677
+D KDS + T + S E +S++E +SD+++
Sbjct: 570 SDEKDSGK-TLDKKPSKEMSSDSEYDSDDDR 599
Score = 101 bits (251), Expect = 9e-21
Identities = 114/537 (21%), Positives = 229/537 (42%), Gaps = 57/537 (10%)
Query: 63 RKDLKPRVEETSVIDARHKEDEEEADELDNKHDEQTKLDDVNGVEDNSEHKEDSVEQESE 122
+K KP+VE S D D+++ ++L K + K N D SE ED+ ++ E
Sbjct: 124 KKTAKPKVEMYSGSD-----DDDDFNKLPKK--AKGKAQKSNKKWDGSEEDEDNSKKIKE 176
Query: 123 ESSQNAKTDL--EGEQHTEKVDEENDNAENKENESVEKENE------------EIKKEVE 168
S N+ + E ++ + + N +NK ++E NE + K E +
Sbjct: 177 RSRINSSGESGDESDEFLQSRKGQKKNQKNKPGPNIESGNEDDDASFKIKTVAQKKAEKK 236
Query: 169 DTETGESIEEKSHLENEESKETGEISEEKSHLENEESKETGESSEEKSHLENEESKETG- 227
+ E + EEK+ L + KE E ++ + + KE+ EE++ ++++ + +TG
Sbjct: 237 ERERKKRDEEKAKLRKLKEKEELETGKK----DQSKQKESQRKFEEET-VKSKVTVDTGV 291
Query: 228 -ESSEEKSHLEN-EENKDEEKSKQENEEIKDGEKIQQENEENKDEE----KSQQEN---- 277
+SEEK+ E+ +E K+++++ K GEK ++E E+ K K+ QE
Sbjct: 292 IPASEEKAETPTAAEDDNEGDKKKKDKKKKKGEKEEKEKEKKKGPSKATVKAMQEALAKL 351
Query: 278 EENKDEEKSQQENELKKNEGGEKETGEITEEKSKQENEETSETNSKDKENEESNQNGSDA 337
+E ++ +K ++E +K+ E E E EE+ +QE E + K+++ +
Sbjct: 352 KEEEERQKREEEERIKRLE--ELEAKRKEEERLEQEKRERKKQKEKERKERLKKEGKLLT 409
Query: 338 KEQVGENHEQDSKQGTEETNGTEGGEKEEHDKIKEDTSSDNQVQDGEKNNEAREENYSGD 397
K Q ++ + G E K+ K K D + + + E++E + S +
Sbjct: 410 KSQREARARAEATLKLLQAQGVEVPSKDSLPK-KRPIYEDKKRKKIPQQLESKEVSESME 468
Query: 398 NASSAVVDNKSQESSNKTEEQFDKKEKNEFELESQKNSNETTESTDSTITQNSQGNESEK 457
++ V E+ +KE+ +E E E T+ + + S++
Sbjct: 469 LCAAVEV----------MEQGVPEKEETPPPVEP-----EEEEDTEDAGLDDWEAMASDE 513
Query: 458 DQAQTENDTPKGSASESDEQKQEQEQNNTTKDDVQTTDTSSQNGNDTTEKQNETSEDANS 517
+ + E +T E+ E+++E+E+ ++D ++ + + G + +E E +
Sbjct: 514 ETEKVEGNTVHIEVKENPEEEEEEEEEE--EEDEESEEEEEEEGESEGSEGDEEDEKVSD 571
Query: 518 KKEDSSALNTTPNNEDSKSGVAGDQADSTTTTSSSETQDGNTNHGEYKDTTNENPEK 574
+K+ L+ P+ E S D T + + + + N N EK
Sbjct: 572 EKDSGKTLDKKPSKEMSSDSEYDSDDDRTKEERAYDKAKRRIEKRRLEHSKNVNTEK 628
Score = 89.0 bits (219), Expect = 4e-17
Identities = 122/683 (17%), Positives = 265/683 (37%), Gaps = 123/683 (18%)
Query: 118 EQESEESSQNAKTDLEGEQHTEKVDEENDNAENKENESVEKENEEIKKEVEDTETGESIE 177
+++ +S + K D++ + +++ E + +S K+ +E KK+ D
Sbjct: 3 KKQKNKSEDSTKDDIDLDALAAEIEGAGAAKEQEPQKSKGKKKKEKKKQDFD-------- 54
Query: 178 EKSHLENEESKETGEISEE----KSHLENEESKETGESSEEKSHLENEESKETGESSEEK 233
E++ KE E+S E K+ E K T + EE +++ K+ G+ +++
Sbjct: 55 -----EDDILKELEELSLEAQGIKADRETVAVKPTENNEEE---FTSKDKKKKGQKGKKQ 106
Query: 234 SHLENEENKDEEKSKQENEEIKDGEKIQQENEENKDEEKSQQENEENKDEEKSQQENELK 293
S +N+ + E+K + + K ++ ++++ D K + K + K+Q+ N K
Sbjct: 107 SFDDNDSEELEDKDSKSKKTAKPKVEMYSGSDDDDDFNKLPK-----KAKGKAQKSN--K 159
Query: 294 KNEGGEKETGEITEEKSKQENEETSETNSKDKENEESNQNGSDAKEQVGENHEQDSKQGT 353
K +G E++ E + ++ +E S NS + +ES++ K G+ Q +K G
Sbjct: 160 KWDGSEED------EDNSKKIKERSRINSSGESGDESDEFLQSRK---GQKKNQKNKPGP 210
Query: 354 EETNGTEGGEKEEHDKIKEDTSSDNQVQDGEKNNEAREENYSGDNASSAVVDNKSQESSN 413
E G +++ K T + + + E+ + R+E + A + K + +
Sbjct: 211 N----IESGNEDDDASFKIKTVAQKKAEKKERERKKRDE----EKAKLRKLKEKEELETG 262
Query: 414 KTEEQFDKKEKNEFELESQKN----------SNETTESTDSTITQNSQGNESEKDQAQTE 463
K ++ K+ + +FE E+ K+ ++E T + +++G++ +KD+ + +
Sbjct: 263 KKDQSKQKESQRKFEEETVKSKVTVDTGVIPASEEKAETPTAAEDDNEGDKKKKDKKKKK 322
Query: 464 NDTPKGSASESDEQKQEQEQNNTTKDDVQTTDTSSQNGNDTTEKQNETSEDANSKKEDSS 523
+ E+K+++++ +K V+ + + E+Q E+ + E+
Sbjct: 323 GEK---------EEKEKEKKKGPSKATVKAMQEALAKLKEEEERQKREEEERIKRLEELE 373
Query: 524 ALNTTPNNEDSKSGVAGDQADSTTTTSSSETQDGNTNHGEYKDTTNENPEKNSGQEGT-- 581
A E+ + + + E + E K T E + E T
Sbjct: 374 A----KRKEEERL-----EQEKRERKKQKEKERKERLKKEGKLLTKSQREARARAEATLK 424
Query: 582 --QESGSSSNTFDN--------KDAASNKVQLTTTSDTSSE----------------QKK 615
Q G + D+ +D K+ S SE +K+
Sbjct: 425 LLQAQGVEVPSKDSLPKKRPIYEDKKRKKIPQQLESKEVSESMELCAAVEVMEQGVPEKE 484
Query: 616 DESSSAESKSESSQNDNANSGQSNTTSDESANDNKDSSQVTTSSENSAEGNSNTENNSDE 675
+ E + E D SDE + ++ EN E E +E
Sbjct: 485 ETPPPVEPEEEEDTEDAGLDDWEAMASDEETEKVEGNTVHIEVKENPEEE----EEEEEE 540
Query: 676 NQNDSKNNENTNDSGNTSNDANVNENQNENAAQTKTSENEGDAQNESVESKKENNESAHK 735
+ D ++ E + G + +EGD ++E V +K++ ++ K
Sbjct: 541 EEEDEESEEEEEEEGESEG-------------------SEGDEEDEKVSDEKDSGKTLDK 581
Query: 736 DVDNNSNSNDQGSSDTSVTQDDK 758
+S+ + SD T++++
Sbjct: 582 KPSKEMSSDSEYDSDDDRTKEER 604
Score = 87.4 bits (215), Expect = 1e-16
Identities = 95/443 (21%), Positives = 188/443 (41%), Gaps = 61/443 (13%)
Query: 39 GHSREQKASYGASTKTGNE-------VVKLGRKDLKPRVEETSVIDARHKEDEEEAD--E 89
G + QK G + ++GNE + + +K + + E R K DEE+A +
Sbjct: 199 GQKKNQKNKPGPNIESGNEDDDASFKIKTVAQKKAEKKERE------RKKRDEEKAKLRK 252
Query: 90 LDNKHDEQT-KLDDVNGVEDNSEHKEDSVE-------------QESEESSQNAKTDLEGE 135
L K + +T K D E + +E++V+ +E E+ A+ D EG+
Sbjct: 253 LKEKEELETGKKDQSKQKESQRKFEEETVKSKVTVDTGVIPASEEKAETPTAAEDDNEGD 312
Query: 136 QHTEKVDEENDNAENKENESVEKENEEIKKEVEDTETGESIEEKSHLENEESKETGEISE 195
+ +K D++ E +E E EK+ K V+ + E + L+ EE ++ E E
Sbjct: 313 K--KKKDKKKKKGEKEEKEK-EKKKGPSKATVKAMQ-----EALAKLKEEEERQKREEEE 364
Query: 196 EKSHLENEESKETGES--SEEKSHLENEESKETGESSEEKSHLENEENKDEEKSKQENEE 253
LE E+K E +EK + ++ KE E +++ L + ++ + +
Sbjct: 365 RIKRLEELEAKRKEEERLEQEKRERKKQKEKERKERLKKEGKLLTKSQREARARAEATLK 424
Query: 254 IKDGEKIQQENEENKDEEKSQQENEENKDEEKSQQENELKKN----------EGGEKETG 303
+ + ++ ++++ +++ E+++ K + + E+ ++ E G E
Sbjct: 425 LLQAQGVEVPSKDSLPKKRPIYEDKKRKKIPQQLESKEVSESMELCAAVEVMEQGVPEKE 484
Query: 304 EITEEKSKQENEETSETNSKD-----KENEESNQNGSDAKEQVGENHEQDSKQGTEETNG 358
E +E E+T + D + E G+ +V EN E++ ++ EE
Sbjct: 485 ETPPPVEPEEEEDTEDAGLDDWEAMASDEETEKVEGNTVHIEVKENPEEEEEEEEEEEED 544
Query: 359 TEGGEKEEHDKIKEDTSSDNQ---VQDGEKNNEAREENYSGDNASSAVVDNKSQESSNKT 415
E E+EE + E + D + V D + + + ++ S + +S + D S + K
Sbjct: 545 EESEEEEEEEGESEGSEGDEEDEKVSDEKDSGKTLDKKPSKEMSSDSEYD--SDDDRTKE 602
Query: 416 EEQFDKKEK--NEFELESQKNSN 436
E +DK ++ + LE KN N
Sbjct: 603 ERAYDKAKRRIEKRRLEHSKNVN 625
Score = 86.7 bits (213), Expect = 2e-16
Identities = 99/568 (17%), Positives = 213/568 (37%), Gaps = 24/568 (4%)
Query: 219 ENEESKETGESSEEKSHLENEENKDEEKSKQENEEIK---DGEKIQQENEENKDEEKSQQ 275
E E K G+ +EK +++ DE+ +E EE+ G K +E K E +++
Sbjct: 34 EQEPQKSKGKKKKEKK----KQDFDEDDILKELEELSLEAQGIKADRETVAVKPTENNEE 89
Query: 276 ENEENKDEEKSQQENELKKNEGGEKETGEITEEKSKQENEETSETNSKDKENEESNQNGS 335
E +KD++K Q+ + + + + E E + KSK+ + E S ++++ N+
Sbjct: 90 E-FTSKDKKKKGQKGKKQSFDDNDSEELEDKDSKSKKTAKPKVEMYSGSDDDDDFNKLPK 148
Query: 336 DAKEQVGENHEQDSKQGTEETNGTEGGEKEEHDKIKEDTSSDNQVQDGEKNNEAREENYS 395
AK + +++++ +E N + E+ + E ++ K + ++N
Sbjct: 149 KAKGKAQKSNKKWDGSEEDEDNSKKIKERSRINSSGESGDESDEFLQSRKGQKKNQKNKP 208
Query: 396 GDNASSA-VVDNKSQESSNKTEEQFDKKEKNEFELESQKNSNETTESTDSTITQNSQGNE 454
G N S D+ S + +++ +KKE+ + + +K + + T ++
Sbjct: 209 GPNIESGNEDDDASFKIKTVAQKKAEKKERERKKRDEEKAKLRKLKEKEELETGKKDQSK 268
Query: 455 SEKDQAQTENDTPKGSASESDEQKQEQEQNNTTKDDVQTTDTSSQNGNDTTEKQNETSED 514
++ Q + E +T K + E+ T + + + D +K+ E E
Sbjct: 269 QKESQRKFEEETVKSKVTVDTGVIPASEEKAETPTAAEDDNEGDKKKKDKKKKKGEKEEK 328
Query: 515 ANSKKEDSSALNTTPNNEDSKSGVAGDQADSTTTTSSSETQDGNTNHGEYKDTTNENPEK 574
KK+ S E +A + + E + E K E E+
Sbjct: 329 EKEKKKGPSKATVKAMQE----ALAKLKEEEERQKREEEERIKRLEELEAKRKEEERLEQ 384
Query: 575 NSGQEGTQESGSSSNTFDNKDAASNKVQLTTTSDTSSEQKKDESSSAESKSESSQNDN-- 632
+ Q+ + K Q + + K ++ E S+ S
Sbjct: 385 EKRERKKQKEKERKERLKKEGKLLTKSQREARARAEATLKLLQAQGVEVPSKDSLPKKRP 444
Query: 633 --ANSGQSNTTSDESANDNKDSSQVTTSSENSAEGNSNTENNSDENQNDSKNNENTNDSG 690
+ + + + +S ++ + E +G E + + + E+T D+G
Sbjct: 445 IYEDKKRKKIPQQLESKEVSESMELCAAVEVMEQGVPEKEETPPPVEPEEE--EDTEDAG 502
Query: 691 NTSNDANVNENQNE----NAAQTKTSENEGDAQNESVESKKENNESAHKDVDNNSNSNDQ 746
+A ++ + E N + EN + + E E ++E+ ES ++ + + +
Sbjct: 503 LDDWEAMASDEETEKVEGNTVHIEVKENP-EEEEEEEEEEEEDEESEEEEEEEGESEGSE 561
Query: 747 GSSDTSVTQDDKESRVDLGTLPESNGES 774
G + D+K+S L P S
Sbjct: 562 GDEEDEKVSDEKDSGKTLDKKPSKEMSS 589
Score = 79.3 bits (194), Expect = 4e-14
Identities = 89/384 (23%), Positives = 166/384 (43%), Gaps = 39/384 (10%)
Query: 60 KLGRKDLKPRVE-ETSVIDA-RHKEDEEEADELDNKHDEQTK--LDDVNGVEDNSEHKED 115
K + +K +V +T VI A K + A E DN+ D++ K E+ + K+
Sbjct: 275 KFEEETVKSKVTVDTGVIPASEEKAETPTAAEDDNEGDKKKKDKKKKKGEKEEKEKEKKK 334
Query: 116 SVEQESEESSQNAKTDLEGEQHTEKVDEEND-------NAENKENESVEKENEEIKKEVE 168
+ + ++ Q A L+ E+ +K +EE A+ KE E +E+E E KK+ E
Sbjct: 335 GPSKATVKAMQEALAKLKEEEERQKREEEERIKRLEELEAKRKEEERLEQEKRERKKQKE 394
Query: 169 DTETGESIEEKSHLENEESKETGEISEEKSHLENEESKETG------------ESSEEKS 216
E E ++++ L + +E +E L + E E + K
Sbjct: 395 K-ERKERLKKEGKLLTKSQREARARAEATLKLLQAQGVEVPSKDSLPKKRPIYEDKKRKK 453
Query: 217 HLENEESKETGESSEEKSHLENEENKDEEKSKQENEEIKDGEKIQQENEENKDEEKSQQE 276
+ ESKE ES E + +E E EK +E + E+ + + D+ ++
Sbjct: 454 IPQQLESKEVSESMELCAAVEVMEQGVPEK--EETPPPVEPEEEEDTEDAGLDDWEAMAS 511
Query: 277 NEENKDEEKSQQENELKKNEGGEKETGEITEEKSKQENEETSETNSKDKENEESNQNGSD 336
+EE + E + E+K+N E+E EE+ ++E+EE+ E +++E E G +
Sbjct: 512 DEETEKVEGNTVHIEVKENPEEEEE-----EEEEEEEDEESEE--EEEEEGESEGSEGDE 564
Query: 337 AKEQVGENHEQDSKQGTEETNGTEGGEKEEH----DKIKEDTSSDNQVQDGEKNNEAREE 392
E+V + E+DS + ++ E E+ D+ KE+ + D + EK +
Sbjct: 565 EDEKVSD--EKDSGKTLDKKPSKEMSSDSEYDSDDDRTKEERAYDKAKRRIEKRRLEHSK 622
Query: 393 NYSGDNASSAVVDNKSQESSNKTE 416
N + + + ++ + KT+
Sbjct: 623 NVNTEKLRAPIICVLGHVDTGKTK 646
Score = 64.3 bits (155), Expect = 1e-09
Identities = 59/308 (19%), Positives = 123/308 (39%), Gaps = 29/308 (9%)
Query: 477 QKQEQEQNNTTKDDVQTTDTSSQNGNDTTEKQNETSEDANSKKEDSSALNTTPNN----- 531
+KQ+ + ++TKDD+ +++ K+ E + KK++ + ++
Sbjct: 3 KKQKNKSEDSTKDDIDLDALAAEIEGAGAAKEQEPQKSKGKKKKEKKKQDFDEDDILKEL 62
Query: 532 EDSKSGVAGDQADSTTTTSSSETQDGNTNHGEYKDTTNENPEKNSGQEGTQES--GSSSN 589
E+ G +AD T T + E + T+ + +K GQ+G ++S + S
Sbjct: 63 EELSLEAQGIKADRETVAVKP------TENNEEEFTSKD--KKKKGQKGKKQSFDDNDSE 114
Query: 590 TFDNKDAASNKVQLTTTSDTSSEQKKDESSSAESKSESSQNDNANSGQSNTTSDESANDN 649
++KD+ S K S D+ + K++ + + ++++
Sbjct: 115 ELEDKDSKSKKTAKPKVEMYSGSDDDDDFNKLPKKAKGKAQKSNKKWDGSEEDEDNSKKI 174
Query: 650 KDSSQVTTSSENSAEGNSNTENNSDENQNDSKNNENTNDSGNTSNDANVNENQNENAAQT 709
K+ S++ +S E+ E + ++ + +N +SGN +DA+ + + AQ
Sbjct: 175 KERSRINSSGESGDESDEFLQSRKGQKKNQKNKPGPNIESGNEDDDASF---KIKTVAQK 231
Query: 710 KTSENEGDAQNESVE-------SKKENNESAHKDVDNNSNSNDQGSSDTSVTQDDKESRV 762
K + E + + E +KE E+ KD S + +T + V
Sbjct: 232 KAEKKERERKKRDEEKAKLRKLKEKEELETGKKDQSKQKESQRKFEEETV----KSKVTV 287
Query: 763 DLGTLPES 770
D G +P S
Sbjct: 288 DTGVIPAS 295
Score = 50.8 bits (120), Expect = 1e-05
Identities = 48/243 (19%), Positives = 106/243 (42%), Gaps = 19/243 (7%)
Query: 60 KLGRKDLKPRVEETSVIDARHK---EDEEEADELDNKHDEQTKLDDVNGVEDNSEHKEDS 116
+L K++ +E + ++ + E EE ++ + +E T + G++D D
Sbjct: 457 QLESKEVSESMELCAAVEVMEQGVPEKEETPPPVEPEEEEDT---EDAGLDDWEAMASDE 513
Query: 117 VEQESEESSQNAKTDLEGEQHTEKVDEENDNAENKENESVEKENEEIKKEVEDTETGESI 176
++ E ++ + + E+ E+ +EE ++ E++E E E E+E + + ED + +
Sbjct: 514 ETEKVEGNTVHIEVKENPEEEEEEEEEEEEDEESEEEEEEEGESEGSEGDEEDEKVSDEK 573
Query: 177 EEKSHLENEESKETGEISEEKSHLENEESKETGESSEEKSHLENEESKETGESSEEK--- 233
+ L+ + SKE SE S +++ +KE + K +E + + + EK
Sbjct: 574 DSGKTLDKKPSKEMSSDSEYDS--DDDRTKEERAYDKAKRRIEKRRLEHSKNVNTEKLRA 631
Query: 234 ------SHLENEENKDEEKSKQENEEIKDGEKIQQENEENKDEEKSQQENEENKDEEKSQ 287
H++ + K +K + + ++DGE + + NE+ K +
Sbjct: 632 PIICVLGHVDTGKTKILDKLR--HTHVQDGEAGGITQQIGATNVPLEAINEQTKMIKNFD 689
Query: 288 QEN 290
+EN
Sbjct: 690 REN 692
>MLH_TETTH (P40631) Micronuclear linker histone polyprotein (MIC LH)
[Contains: Micronuclear linker histone-alpha;
Micronuclear linker histone-beta; Micronuclear linker
histone-delta; Micronuclear linker histone-gamma]
Length = 633
Score = 120 bits (301), Expect = 1e-26
Identities = 116/616 (18%), Positives = 248/616 (39%), Gaps = 49/616 (7%)
Query: 139 EKVDEENDNAENKE-----NESVEKENEEIKKEVEDTETGESIEEKSHLENEESKETGEI 193
EK + N +NK+ N+ E E ++K V++ E EE H N + +
Sbjct: 27 EKKNALGKNFDNKKVQADYNKLSNNEKERLQKLVDNAEEKYK-EELFHYNNHIQGKGKQK 85
Query: 194 SEEKSHLENEESKETG------ESSEEK---SHLENEESKETGESSEEKSHLENEENKDE 244
+ + + K G E + +K H + +K SE+ ++L +E K
Sbjct: 86 YVPQVKVPEKPKKPIGSFFRFLEENRQKYAAKHKDLTNAKILKIMSEDFNNLPQKEVKVY 145
Query: 245 EKSKQEN--EEIKDGEKIQQENEENKDEEKSQQENEENKDEEKSQQENELKKNEGGEKET 302
E + Q+ + + + +K ++ + +++++++N +K +S + + ++G K T
Sbjct: 146 EDAYQKEYAQYLVEFKKWNEKYGQAAQKKQTKRKNSTSKSR-RSSSKGKSSVSKGRTKST 204
Query: 303 GEITE-EKSKQENEETSETNSKDKENEESNQNGSDAKEQVGENHEQDSKQGTEETNGTEG 361
+ S + S ++++ K + +Q G+ + + N + + + N +
Sbjct: 205 SSKRRADSSASQGRSQSSSSNRRKASSSKDQKGTRSSSRKASNSKGRKNSTSNKRNSSSS 264
Query: 362 GEKEEHDKIKEDTSSDNQVQDGEKNNEAREENYSGDNASSAVVDNKSQESSNKTEEQFDK 421
++ K K+ +SS N+ K ++ G ASS+ S+K++++
Sbjct: 265 SKRSSSSKNKKSSSSKNKKSSSSKGRKSSSSR--GRKASSS-----KNRKSSKSKDRKSS 317
Query: 422 KEKNEFELESQKNSNETTESTDSTITQNSQGNESEKDQAQTENDTPKGSASESDEQKQEQ 481
K S K++ S+ + +S+G +S K Q + + E + QK+ Q
Sbjct: 318 SSKGRKSSSSSKSNKRKASSSRGRKSSSSKGRKSSKSQERKNSHADTSKQMEDEGQKRRQ 377
Query: 482 EQNNTTKDDVQTTDTSSQNGNDTTEKQNETSEDANSKKEDSSALNTTPNNEDSKSGVAGD 541
++ +D+ SS+ + K+ T + AN+K ++ + + + S S G
Sbjct: 378 SSSSAKRDE------SSKKSRRNSMKEARTKK-ANNKSASKASKSGSKSKGKSASKSKGK 430
Query: 542 QADSTTTTSSSETQDGNTNHGEYKDTTNENPEKNSGQEGTQESGSSSNTFDNKDAASNKV 601
+ + S +N + + T++ + + T ++ + + KD + K
Sbjct: 431 SSSKGKNSKSRSASKPKSNAAQNSNNTHQTADSSENASSTTQTRTRGRQREQKDMVNEKS 490
Query: 602 QLTTTSDTSSEQKKDESSSAESKSESSQNDNANSGQSNTTSDESANDNKDSSQVTTSSE- 660
++S K + S ++SKS S NA+ + +TT+ +K S+ + SE
Sbjct: 491 NSKSSSKGKKNSKSNTRSKSKSKSASKSRKNASKSKKDTTNHGRQTRSKSRSESKSKSEA 550
Query: 661 -NSAEGNSNTENNSDENQNDSKNNENTNDSGNTSNDANVNENQNENAAQTKTSENEGDAQ 719
N E +D K E+ + S ++D K S+N D++
Sbjct: 551 PNKPSNKMEVIEQPKEESSDRKRRESRSQSAKKTSD--------------KKSKNRSDSK 596
Query: 720 NESVESKKENNESAHK 735
+ E K+NN K
Sbjct: 597 KMTAEDPKKNNAEDSK 612
Score = 113 bits (282), Expect = 2e-24
Identities = 113/629 (17%), Positives = 258/629 (40%), Gaps = 59/629 (9%)
Query: 100 LDDVNGVEDNSEHKEDSVEQESEESSQNAKTDLEG------EQHTEKVDEENDNAENKEN 153
L+ N + N ++K+ V+ + + S N K L+ E++ E++ N++ + K
Sbjct: 26 LEKKNALGKNFDNKK--VQADYNKLSNNEKERLQKLVDNAEEKYKEELFHYNNHIQGKGK 83
Query: 154 ESV-------EKENEEIKKEVEDTETGESIEEKSHLENEESKETGEISEEKSHLENEESK 206
+ EK + I E H + +K +SE+ ++L +E K
Sbjct: 84 QKYVPQVKVPEKPKKPIGSFFRFLEENRQKYAAKHKDLTNAKILKIMSEDFNNLPQKEVK 143
Query: 207 ETGESSEEKSHLE-----NEESKETGESSEEK-SHLENEENKDEEKSKQENEEIKDGEKI 260
E + +K + + + +++ G+++++K + +N +K S + + G
Sbjct: 144 -VYEDAYQKEYAQYLVEFKKWNEKYGQAAQKKQTKRKNSTSKSRRSSSKGKSSVSKGRTK 202
Query: 261 QQENEENKDEEKSQQENEENKDEEKSQQENELKKNEGGEKETGEITEEKSKQENEETSET 320
++ D SQ ++ + + ++ +K T S++ +
Sbjct: 203 STSSKRRADSSASQGRSQSSSSNRRKASSSKDQKG----------TRSSSRKAS------ 246
Query: 321 NSKDKENEESNQ-NGSDAKEQVGENHEQDSKQGTEETNGTEGGEKEEHDKIKEDTSSDNQ 379
NSK ++N SN+ N S + ++ + + S + + + G K + ++ +SS N+
Sbjct: 247 NSKGRKNSTSNKRNSSSSSKRSSSSKNKKSSSSKNKKSSSSKGRKSSSSRGRKASSSKNR 306
Query: 380 VQDGEKNNEAREENYSGDNASSAVVDNKSQESSNKTEEQFDKKEKNEFELESQKNSNETT 439
K+ + + + G +SS+ NK + SS++ + K + + + +KNS+
Sbjct: 307 --KSSKSKDRKSSSSKGRKSSSSSKSNKRKASSSRGRKSSSSKGRKSSKSQERKNSH--- 361
Query: 440 ESTDSTITQNSQGNESEKDQAQTEND-TPKGSASESDEQKQEQEQNNTTKDDVQTTDTSS 498
D++ +G + + + + D + K S S ++ + ++ NN + + + S
Sbjct: 362 --ADTSKQMEDEGQKRRQSSSSAKRDESSKKSRRNSMKEARTKKANNKSASKASKSGSKS 419
Query: 499 QNGNDTTEKQNETSEDANSKKEDSSALNTTPNNEDSKSGVAGDQADSTTTTSSSETQDGN 558
+ + + K +S+ NSK +S + + + D +++ ++T+ + T+
Sbjct: 420 KGKSASKSKGKSSSKGKNSKSRSASKPKSNAAQNSNNTHQTADSSENASSTTQTRTRG-- 477
Query: 559 TNHGEYKDTTNENPEKNSGQEGTQESGSSSNTFDNKDAASNKVQLTTTSDTSSEQKKDES 618
E KD NE S +G + S S++ + +AS + +S+ KKD +
Sbjct: 478 -RQREQKDMVNEKSNSKSSSKGKKNSKSNTRSKSKSKSASK------SRKNASKSKKDTT 530
Query: 619 S---SAESKSESSQNDNANSGQSNTTSDESANDNKDSSQVTTSSENSAEGNSNTENNSDE 675
+ SKS S + + + E K+ S E+ ++ T + +
Sbjct: 531 NHGRQTRSKSRSESKSKSEAPNKPSNKMEVIEQPKEESSDRKRRESRSQSAKKTSDKKSK 590
Query: 676 NQNDSKNNENTNDSGNTSNDANVNENQNE 704
N++DSK + N + D+ + E
Sbjct: 591 NRSDSKKMTAEDPKKNNAEDSKGKKKSKE 619
Score = 105 bits (263), Expect = 4e-22
Identities = 92/537 (17%), Positives = 204/537 (37%), Gaps = 29/537 (5%)
Query: 84 EEEADELDNKHDEQT--KLDDVNGVEDNSEHKEDSVEQESEESSQNAKTDLEGEQHTEKV 141
EE + KH + T K+ + + N+ +++ E + A+ +E ++ EK
Sbjct: 108 EENRQKYAAKHKDLTNAKILKIMSEDFNNLPQKEVKVYEDAYQKEYAQYLVEFKKWNEKY 167
Query: 142 DEENDNAENKENESVEKENEEIKKEVEDTETGESIEEKSHLENEESKETGEISEEKSHLE 201
+ + K S K K G + S + S G S+
Sbjct: 168 GQAAQKKQTKRKNSTSKSRRSSSKGKSSVSKGRTKSTSSKRRADSSASQGRSQSSSSNRR 227
Query: 202 ----NEESKETGESSEEKSHLENEESKETGESSEEKSHLENEENKDEEKSKQENEEIKDG 257
+++ K T SS + S+ + ++ + + + S + +K+++ S +N++
Sbjct: 228 KASSSKDQKGTRSSSRKASNSKGRKNSTSNKRNSSSSSKRSSSSKNKKSSSSKNKKSSSS 287
Query: 258 EKIQQENEENKDEEKSQQENEENKDEEKSQQENELKKNEGGEKETGEITEEKSKQENEET 317
+ + + + S+ + KS K + + + + + ++ +
Sbjct: 288 KGRKSSSSRGRKASSSKNRKSSKSKDRKSSSSKGRKSSSSSKSNKRKASSSRGRKSSSSK 347
Query: 318 SETNSKDKENEESNQNGSDAKEQVGENHEQDSKQGTEETNGTEGGEKEEHDKIKEDTSSD 377
+SK +E + S+ + S E G+ Q S + E +K + +KE +
Sbjct: 348 GRKSSKSQERKNSHADTSKQMEDEGQKRRQSSSSAKRD----ESSKKSRRNSMKEARTK- 402
Query: 378 NQVQDGEKNNEAREENYSGDNASSAVVDNKSQESSNKTEEQFDKKEKNEFELESQKNSNE 437
+ NN++ + + S +KS+ S+ + + ++ + + +NSN
Sbjct: 403 ------KANNKSASKASKSGSKSKGKSASKSKGKSSSKGKNSKSRSASKPKSNAAQNSNN 456
Query: 438 TTESTD------STITQNSQGNESEKDQAQTENDTPKGSASESDEQKQEQEQNNTTKDDV 491
T ++ D ST ++G + E+ E K S+ K + +K
Sbjct: 457 THQTADSSENASSTTQTRTRGRQREQKDMVNEKSNSKSSSKGKKNSKSNTRSKSKSKSAS 516
Query: 492 QTTDTSSQNGNDTTEKQNETSEDANSKKEDSSALNTTPNN-----EDSKSGVAGDQADST 546
++ +S++ DTT +T + S+ + S P+N E K + + +
Sbjct: 517 KSRKNASKSKKDTTNHGRQTRSKSRSESKSKSEAPNKPSNKMEVIEQPKEESSDRKRRES 576
Query: 547 TTTSSSETQDGNT-NHGEYKDTTNENPEKNSGQEGTQESGSSSNTFDNKDAASNKVQ 602
+ S+ +T D + N + K T E+P+KN+ ++ + S +NK Q
Sbjct: 577 RSQSAKKTSDKKSKNRSDSKKMTAEDPKKNNAEDSKGKKKSKEGKTGAYGKKANKKQ 633
Score = 104 bits (260), Expect = 8e-22
Identities = 104/598 (17%), Positives = 260/598 (43%), Gaps = 40/598 (6%)
Query: 193 ISEEKSHL-ENEESKETGESSEEKSHLENEESKETGESSEEK--SHLENEENKDEEKSKQ 249
+ E+K+ L +N ++K+ + S+ E E ++ +++EEK L + N + K KQ
Sbjct: 25 VLEKKNALGKNFDNKKVQADYNKLSNNEKERLQKLVDNAEEKYKEELFHYNNHIQGKGKQ 84
Query: 250 EN-EEIKDGEKIQQEN-------EENKDEEKSQQENEENKDEEKSQQENELKKNEGGEKE 301
+ ++K EK ++ EEN+ + ++ ++ N K E+ N +KE
Sbjct: 85 KYVPQVKVPEKPKKPIGSFFRFLEENRQKYAAKHKDLTNAKILKIMSEDF---NNLPQKE 141
Query: 302 TGEITEEKSKQENEETSETNSKDKENEESNQNGSDAKEQVGENHEQDSKQGTEETNGTEG 361
+ K+ + E +++ ++ Q ++ + S +G +++ ++G
Sbjct: 142 VKVYEDAYQKEYAQYLVEFKKWNEKYGQAAQKKQTKRKNSTSKSRRSSSKG--KSSVSKG 199
Query: 362 GEKEEHDKIKEDTSSDNQVQDGEKNNEAREENYSGDNASSAVVDNKSQESSNKTEEQFDK 421
K K + D+S+ +Q + ++ R+ + S D + K+ S + +K
Sbjct: 200 RTKSTSSKRRADSSA-SQGRSQSSSSNRRKASSSKDQKGTRSSSRKASNSKGRKNSTSNK 258
Query: 422 KEKNEFELESQKNSNETTESTDSTITQNSQGNESEKDQAQTENDTPKGSASESDEQKQEQ 481
+ + S + N+ + S+ + + +S+G +S + + + + +S+S ++K
Sbjct: 259 RNSSSSSKRSSSSKNKKSSSSKNKKSSSSKGRKSSSSRGRKASSSKNRKSSKSKDRKSSS 318
Query: 482 EQNNTTKDDVQTTDTSSQNGNDTTEKQNETSEDANSKKEDSSALNTTPNNEDSKSGVAGD 541
+ + ++ + + ++ + + S++ +S +T+ ED
Sbjct: 319 SKGRKSSSSSKSNKRKASSSRGRKSSSSKGRKSSKSQERKNSHADTSKQMEDEGQKRRQS 378
Query: 542 QADSTTTTSSSETQDGNTNHGEYKDTTNENPEKNSGQEGTQESGSSSNTFDNKDAASNKV 601
+ + SS +++ + K N++ K S + G++ G S++ K ++ K
Sbjct: 379 SSSAKRDESSKKSRRNSMKEARTKKANNKSASKAS-KSGSKSKGKSASKSKGKSSSKGK- 436
Query: 602 QLTTTSDTSSEQKKDESSSAESKSESSQNDNANSGQSNTTSDES---ANDNKDSSQVTTS 658
+ S K +S++A++ + + Q +++ S+TT + + KD ++
Sbjct: 437 -----NSKSRSASKPKSNAAQNSNNTHQTADSSENASSTTQTRTRGRQREQKDMVNEKSN 491
Query: 659 SENSAEGNSNTENN----------SDENQNDSKNNENTNDSGNTSNDANVNENQNENAAQ 708
S++S++G N+++N S +N SK+ ++T + G + + +E+++++ A
Sbjct: 492 SKSSSKGKKNSKSNTRSKSKSKSASKSRKNASKSKKDTTNHGRQTRSKSRSESKSKSEAP 551
Query: 709 TKTS---ENEGDAQNESVESKKENNESAHKDVDNNSNSNDQGSSDTSVTQDDKESRVD 763
K S E + ES + K+ + S ++ S ++ S +D K++ +
Sbjct: 552 NKPSNKMEVIEQPKEESSDRKRRESRSQSAKKTSDKKSKNRSDSKKMTAEDPKKNNAE 609
Score = 103 bits (258), Expect = 1e-21
Identities = 106/568 (18%), Positives = 235/568 (40%), Gaps = 53/568 (9%)
Query: 119 QESEESSQNAKTDLEGEQHTEKVDEENDNAENKE----NESVEKENEEIKKEVE--DTET 172
+E+ + DL + + + E+ +N KE ++ +KE + E + + +
Sbjct: 108 EENRQKYAAKHKDLTNAKILKIMSEDFNNLPQKEVKVYEDAYQKEYAQYLVEFKKWNEKY 167
Query: 173 GESIEEK-SHLENEESKETGEISEEKSHLENEESKETGESSEEKSHLENEESKETGESSE 231
G++ ++K + +N SK S+ KS + +K T SS+ ++ + + SS
Sbjct: 168 GQAAQKKQTKRKNSTSKSRRSSSKGKSSVSKGRTKST--SSKRRADSSASQGRSQSSSSN 225
Query: 232 EKSHLENEENKDEEKSKQENEEIKDGEKIQQENEENKDEEKSQQENEENKDEEKSQQENE 291
+ +++ K S ++ K G K N+ N + + +NK + S +N+
Sbjct: 226 RRKASSSKDQKGTRSSSRKASNSK-GRKNSTSNKRNSSSSSKRSSSSKNK--KSSSSKNK 282
Query: 292 LKKNEGGEKETGEITEEKSKQENEETSETNSKDKENEESNQNGSDAKEQVGENHEQDSK- 350
+ G K + + S +N ++S+ SKD+++ S S + + + S+
Sbjct: 283 KSSSSKGRKSSSSRGRKASSSKNRKSSK--SKDRKSSSSKGRKSSSSSKSNKRKASSSRG 340
Query: 351 QGTEETNGTEGGEKEEHDKIKEDTSSDNQVQDGEKNNEAREENYSGDNASSAVVDNKSQE 410
+ + + G + + +E DTS + +G+K ++ +SSA D S++
Sbjct: 341 RKSSSSKGRKSSKSQERKNSHADTSKQME-DEGQKRRQS---------SSSAKRDESSKK 390
Query: 411 SS-NKTEEQFDKKEKNEFELESQKNSNETT-ESTDSTITQNSQGNESEKDQAQTENDTPK 468
S N +E KK N+ ++ K+ +++ +S + ++S ++ K ++ ++ +
Sbjct: 391 SRRNSMKEARTKKANNKSASKASKSGSKSKGKSASKSKGKSSSKGKNSKSRSASKPKSNA 450
Query: 469 GSASESDEQKQEQEQNNTTKDDVQTTDTSSQNGNDTTEKQNETSEDANSKKEDSSALNTT 528
S + Q + +N ++ +T + + EK N S K S+ + +
Sbjct: 451 AQNSNNTHQTADSSENASSTTQTRTRGRQREQKDMVNEKSNSKSSSKGKKNSKSNTRSKS 510
Query: 529 PNNEDSKSGVAGDQADSTTTTSSSETQDGNTNHGEYKDTTNENPEKNSGQEGTQESGSSS 588
+ SKS ++S+++ TNHG Q ++ S
Sbjct: 511 KSKSASKS-----------RKNASKSKKDTTNHGR--------------QTRSKSRSESK 545
Query: 589 NTFDNKDAASNKVQ-LTTTSDTSSEQKKDESSSAESKSESSQNDNANSGQSNTTSDESAN 647
+ + + SNK++ + + SS++K+ ES S +K S + S T+++
Sbjct: 546 SKSEAPNKPSNKMEVIEQPKEESSDRKRRESRSQSAKKTSDKKSKNRSDSKKMTAEDPKK 605
Query: 648 DNKDSSQVTTSSENSAEGNSNTENNSDE 675
+N + S+ S+ G + N +
Sbjct: 606 NNAEDSKGKKKSKEGKTGAYGKKANKKQ 633
Score = 85.5 bits (210), Expect = 5e-16
Identities = 96/461 (20%), Positives = 189/461 (40%), Gaps = 49/461 (10%)
Query: 336 DAKEQVGENHEQDSKQGTEETNGTEGGEKEEHDKIKEDTSSDNQVQDGEKNNEAREENYS 395
+ K +G+N D+K+ + N EKE K+ ++ + + NN +
Sbjct: 27 EKKNALGKNF--DNKKVQADYNKLSNNEKERLQKLVDNAEEKYKEELFHYNNHIQ----- 79
Query: 396 GDNASSAVVDNKSQESSNKT--------EEQFDKKEKNEFELESQKNSNETTESTDSTIT 447
G V K E K EE K +L + K +E ++
Sbjct: 80 GKGKQKYVPQVKVPEKPKKPIGSFFRFLEENRQKYAAKHKDLTNAKILKIMSEDFNNLPQ 139
Query: 448 QNSQGNES--EKDQAQTENDTPKGSAS--ESDEQKQEQEQNNTTKDDVQTTDTSSQNGND 503
+ + E +K+ AQ + K + ++ ++KQ + +N+T+K + SS G
Sbjct: 140 KEVKVYEDAYQKEYAQYLVEFKKWNEKYGQAAQKKQTKRKNSTSK-----SRRSSSKGKS 194
Query: 504 TTEKQNETSEDANSKKEDSSALNTTPNNEDSKSGVAGDQADSTTTTSSSETQDGNTNHGE 563
+ K T ++ ++ DSSA + S A D T SSS + + + G
Sbjct: 195 SVSK-GRTKSTSSKRRADSSASQGRSQSSSSNRRKASSSKDQKGTRSSS--RKASNSKGR 251
Query: 564 YKDTTNENPEKNSGQEGTQESGSSSNTFDNKDAASNKVQLTTTSDTSSEQKKDESSSAES 623
T+N+ +S + + S++ NK ++S+K + SS + ++SS+++
Sbjct: 252 KNSTSNKRNSSSSSKRSSSSKNKKSSSSKNKKSSSSKGR------KSSSSRGRKASSSKN 305
Query: 624 KSESSQNDNANSGQSNTTSDESANDNKDSSQVTTSSENSAEGNSNTENNSDENQNDSKNN 683
+ S D +S S S+ NK A + +++S + + SK+
Sbjct: 306 RKSSKSKDRKSSSSKGRKSSSSSKSNK----------RKASSSRGRKSSSSKGRKSSKSQ 355
Query: 684 ENTNDSGNTSND-ANVNENQNENAAQTKTSENEGDAQNESVE---SKKENNESAHKDVDN 739
E N +TS + + + ++++ K E+ ++ S++ +KK NN+SA K +
Sbjct: 356 ERKNSHADTSKQMEDEGQKRRQSSSSAKRDESSKKSRRNSMKEARTKKANNKSASKASKS 415
Query: 740 NSNSNDQGSSDT--SVTQDDKESRVDLGTLPESNGESHHND 778
S S + +S + + K S+ + P+SN + N+
Sbjct: 416 GSKSKGKSASKSKGKSSSKGKNSKSRSASKPKSNAAQNSNN 456
Score = 84.3 bits (207), Expect = 1e-15
Identities = 83/401 (20%), Positives = 176/401 (43%), Gaps = 37/401 (9%)
Query: 384 EKNNEAREENYSGDNASSAVVDNKSQESSNKTEEQFDKKEKNEFELESQKNSNETTESTD 443
+K + E+ Y + A V K E + ++ K KN S S ++
Sbjct: 139 QKEVKVYEDAYQKEYAQYLVEFKKWNEKYGQAAQKKQTKRKN-----STSKSRRSSSKGK 193
Query: 444 STITQNSQGNESEKDQAQTENDTPKGSASESDEQKQEQEQNNTTKDDVQTTDTSSQNGND 503
S++++ + S K +A + + +S S+ +K + D + T +SS+ ++
Sbjct: 194 SSVSKGRTKSTSSKRRADSSASQGRSQSSSSNRRKASSSK------DQKGTRSSSRKASN 247
Query: 504 TTEKQNETSEDANSKKEDSSALNTTPNNEDSKSGVAGDQADSTTTTSSSETQDGNTNHGE 563
+ ++N TS NS SS +++ N+ S S ++ S+ SS ++ + +
Sbjct: 248 SKGRKNSTSNKRNSSS--SSKRSSSSKNKKSSSS-KNKKSSSSKGRKSSSSRGRKASSSK 304
Query: 564 YKDTTNENPEKNSGQEGTQESGSSSNTFDNKDAASNKVQLTTTSDTSSEQKKDESSSAES 623
+ ++ K+S +G + S SS + NK AS SS +K SS
Sbjct: 305 NRKSSKSKDRKSSSSKGRKSSSSSKS---NKRKAS-----------SSRGRKSSSSKGRK 350
Query: 624 KSESSQNDNANSGQSNTTSDESANDNKDSSQVTTS-SENSAEGNSNTENNSDE--NQNDS 680
S+S + N+++ S DE + SS S + NS E + + N++ S
Sbjct: 351 SSKSQERKNSHADTSKQMEDEGQKRRQSSSSAKRDESSKKSRRNSMKEARTKKANNKSAS 410
Query: 681 KNNENTNDSGNTSNDANVNENQNENAAQTKTSENEGDAQNESVESKKENNESAHKDVDNN 740
K + SG+ S + ++++ +++++ K S++ ++ +S ++ NN H+ D++
Sbjct: 411 K----ASKSGSKSKGKSASKSKGKSSSKGKNSKSRSASKPKSNAAQNSNN--THQTADSS 464
Query: 741 SNSNDQGSSDTSVTQDDKESRVDLGTLPESNGESHHNDVSS 781
N++ + T Q +++ V+ + +S+ + N S+
Sbjct: 465 ENASSTTQTRTRGRQREQKDMVNEKSNSKSSSKGKKNSKSN 505
Score = 75.9 bits (185), Expect = 4e-13
Identities = 73/364 (20%), Positives = 136/364 (37%), Gaps = 35/364 (9%)
Query: 41 SREQKASYGASTKTGNEVVKLGRKDLKPRVEETSVIDARHKEDEEEADELDNKHDEQTKL 100
S K +S+K GRK R + S R ++ +K + +
Sbjct: 268 SSSSKNKKSSSSKNKKSSSSKGRKSSSSRGRKASSSKNRKSSKSKDRKSSSSKGRKSSSS 327
Query: 101 DDVNGVEDNSEHKEDSVEQESEESSQ-----NAKTDLEGEQHTEKVDEENDNAENKENES 155
N + +S S + +SS+ N+ D + E ++ K +ES
Sbjct: 328 SKSNKRKASSSRGRKSSSSKGRKSSKSQERKNSHADTSKQMEDEGQKRRQSSSSAKRDES 387
Query: 156 VEKENEEIKKEVEDTETGESIEEKSHLENEESK-ETGEISEEKSHLENEESKETGESSEE 214
+K KE + K+ +SK ++ S+ KS + + SK S +
Sbjct: 388 SKKSRRNSMKEARTKKANNKSASKASKSGSKSKGKSASKSKGKSSSKGKNSKSRSASKPK 447
Query: 215 KSHLENEESK-ETGESSEEKSHL-------ENEENKDEEKSKQENEEIKDGEKIQQENEE 266
+ +N + +T +SSE S E KD K ++ G+K + N
Sbjct: 448 SNAAQNSNNTHQTADSSENASSTTQTRTRGRQREQKDMVNEKSNSKSSSKGKKNSKSNTR 507
Query: 267 NKDEEKSQQENEEN-----------------KDEEKSQQENELKKNEGGEKETGEITEEK 309
+K + KS ++ +N K +S+ ++E + E E +E+
Sbjct: 508 SKSKSKSASKSRKNASKSKKDTTNHGRQTRSKSRSESKSKSEAPNKPSNKMEVIEQPKEE 567
Query: 310 SKQENEETSETNSKDKENEESNQNGSDAKEQVGE----NHEQDSKQGTEETNGTEGGEKE 365
S S + S K +++ ++N SD+K+ E N+ +DSK + G G +
Sbjct: 568 SSDRKRRESRSQSAKKTSDKKSKNRSDSKKMTAEDPKKNNAEDSKGKKKSKEGKTGAYGK 627
Query: 366 EHDK 369
+ +K
Sbjct: 628 KANK 631
Score = 68.6 bits (166), Expect = 6e-11
Identities = 74/323 (22%), Positives = 138/323 (41%), Gaps = 42/323 (13%)
Query: 41 SREQKASYGASTKTGNEVVKLGRKDLKPRVEETSVID-ARHKEDEEEADELDN---KHDE 96
S ++KAS K+ + GRK K + + S D ++ EDE + + K DE
Sbjct: 330 SNKRKASSSRGRKSSSSK---GRKSSKSQERKNSHADTSKQMEDEGQKRRQSSSSAKRDE 386
Query: 97 QTKLDDVNGVEDNSEHKEDSVEQESEESSQNAKTDLEGEQHTEKVDEENDNAENKENESV 156
+K N +++ K ++ + S+ S +K+ +G+ ++ + + +N ++ S
Sbjct: 387 SSKKSRRNSMKEARTKKANN-KSASKASKSGSKS--KGKSASKSKGKSSSKGKNSKSRSA 443
Query: 157 EKENEEIKKEVEDT-ETGESIEEKSHLENEESKETGEISEEKSHLENEESKETGESSEEK 215
K + +T +T +S E S +++ G E+K + NE+S S +K
Sbjct: 444 SKPKSNAAQNSNNTHQTADSSENAS--STTQTRTRGRQREQKD-MVNEKSNSKSSSKGKK 500
Query: 216 SHLENEESKETGESSEEKSHLENEENKD--------------EEKSKQE--NEEIKDGEK 259
+ N SK +S+ + ++ KD E KSK E N+ E
Sbjct: 501 NSKSNTRSKSKSKSASKSRKNASKSKKDTTNHGRQTRSKSRSESKSKSEAPNKPSNKMEV 560
Query: 260 IQQENEENKDEEKSQQENEENK--DEEKSQQENELKKNEGGEKETGEITEEKSKQENEET 317
I+Q EE+ D ++ + ++ K ++KS+ ++ KK +T E K+ N E
Sbjct: 561 IEQPKEESSDRKRRESRSQSAKKTSDKKSKNRSDSKK----------MTAEDPKKNNAED 610
Query: 318 SETNSKDKENEESNQNGSDAKEQ 340
S+ K KE + K+Q
Sbjct: 611 SKGKKKSKEGKTGAYGKKANKKQ 633
>RRB1_MOUSE (Q99PL5) Ribosome-binding protein 1 (Ribosome receptor
protein) (mRRp)
Length = 1605
Score = 120 bits (300), Expect = 2e-26
Identities = 132/662 (19%), Positives = 250/662 (36%), Gaps = 58/662 (8%)
Query: 138 TEKVDEENDNAEN--KENESVEKENEEIKKEVEDTETGESIEEKSHLENEESKETGEISE 195
T ++ A+N K+ E + + ++ + + GE + ++ + E ++ G+ E
Sbjct: 194 TSSQGKKGQGAQNQAKKGEGAQNQGKKGEGAQNQAKKGEGAQNQAK-KGEGAQNQGKKGE 252
Query: 196 EKSHLENEESKETGESSEEKSHLENEESKETGESSEEKSHLENEENKDEEKSKQENEEIK 255
+N+ K G ++ K + + GE ++ + +K + + K
Sbjct: 253 GA---QNQAKKGEGGQNQAKKGEGAQNQGKKGEGAQNQGKKGEGAQNQAKKGEGAQNQAK 309
Query: 256 DGEKIQQENEENKDEEKSQQENEENKDEEKSQQ--ENELKKNEGGEKET--GEITEEKSK 311
GE Q + ++ + + ++ E +++ K + +N+ KK EG + + GE + ++K
Sbjct: 310 KGEGAQNQGKKGEGAQNQSKKGEGAQNQAKKGEGGQNQAKKGEGAQNQAKKGEGAQNQAK 369
Query: 312 Q----ENEETSETNSKDKENEESNQNGSDAKEQVGENHEQDSKQGTEETN-GTEGGEKEE 366
+ +N+ + ++ N + AK+ GE + +K+G N G +G ++
Sbjct: 370 KGEGVQNQAKKGVEGAQNQGKKGEANQNQAKK--GEGGQNQTKKGEGPQNQGKKGEAAQK 427
Query: 367 HDKIKEDTSSDNQVQDGEKNNEAREENYSGDNASSAVVDNKSQESSNKTEEQFDKKEKNE 426
DK E + + +G N + E N+S++ + Q K E +
Sbjct: 428 QDKKIEGAQNQGKKPEGTSNQGKKGEGAQNQGKKGEGAQNQSKKGEG-AQNQAKKGEGGQ 486
Query: 427 FELESQKNSNETTESTDSTITQNSQG----NESEKDQAQTENDTPKGSASESDEQKQEQE 482
+ + + + + + Q +G N+++K +N KG A+++ +K E
Sbjct: 487 NQAKKGEGAQNQAKKGEGAQNQAKKGEGVQNQAKKGVEGAQNQGKKGEANQNQAKKGEGG 546
Query: 483 QNNTTKDDVQTTDTSSQNGNDTTEKQNETSEDANSKKEDSSALNTTPNNEDSKSGVAGDQ 542
QN T K + G K+ E ++ + K E + P S G G+
Sbjct: 547 QNQTKKGE----------GPQNQGKKGEAAQKQDKKIEGAQNQGKKPEG-TSNQGKKGEG 595
Query: 543 ADSTTTTSSSETQDGNTNHGEYKDTTNENPEKNSGQ--EGTQESGSSSNTFDNKDAASNK 600
A + G G +N G+ EG Q G N+
Sbjct: 596 AQNQGKKGEGAQNQGKKGEGAQNQGKKGEGAQNQGKKGEGAQNQGKKGEGAQNQGKKGEG 655
Query: 601 VQLTTTSDTSSEQKKDESSSAES-KSESSQND--NANSGQSNTTSDESANDNKDSSQVTT 657
Q ++ KK E ++ K E +QN Q+ E A + ++
Sbjct: 656 AQ--------NQGKKGEGPQNQAKKGEGAQNQGKKGEGAQNQGKKGEGAQNQGKKAEGVQ 707
Query: 658 SSENSAEGNSNTENNSDENQNDSKNNEN-TNDSGNTSNDANVNENQNENAAQTKTSE--- 713
S EG N D N N K E +N + T AN Q + Q K SE
Sbjct: 708 SQSKKGEGTQNQGKKGDGNPNQGKKGEGASNQNRKTDTVANQGTKQEGVSNQVKKSEGSP 767
Query: 714 NEG----DAQNESVESKKENNESAHKDVDNNSNSNDQGSSDTSVTQDDKESRVDLGTLPE 769
N+G A N+ KK+ + S K VD +N + S+ + Q K S V P+
Sbjct: 768 NQGKKAEGAPNQG--KKKDGSPSQAKKVDAAANQGKK--SEMAPAQGQKASMVQSQEAPK 823
Query: 770 SN 771
+
Sbjct: 824 QD 825
Score = 119 bits (298), Expect = 3e-26
Identities = 125/656 (19%), Positives = 249/656 (37%), Gaps = 54/656 (8%)
Query: 105 GVEDNSEHKEDSVEQESE-ESSQNAKTDLEGEQHTEKVDEENDNAENKENESVEKENEEI 163
G ++ ++ E + Q + E +QN EG Q+ K E N + K+ E + + ++
Sbjct: 203 GAQNQAKKGEGAQNQGKKGEGAQNQAKKGEGAQNQAKKGEGAQN-QGKKGEGAQNQAKKG 261
Query: 164 KKEVEDTETGESIEEKSH----LENEESKETGEISEEKSH--LENEESKETGESSEEKSH 217
+ + GE + + +N+ K G ++ K +N+ K G ++ K
Sbjct: 262 EGGQNQAKKGEGAQNQGKKGEGAQNQGKKGEGAQNQAKKGEGAQNQAKKGEGAQNQGKKG 321
Query: 218 LENEESKETGESSEEKSHLENEENKDEEKSKQENEEIKDGEKIQQENEENK---DEEKSQ 274
+ + GE ++ ++ +K + + K GE Q + ++ + ++ K
Sbjct: 322 EGAQNQSKKGEGAQNQAKKGEGGQNQAKKGEGAQNQAKKGEGAQNQAKKGEGVQNQAKKG 381
Query: 275 QENEENKDEEKSQQENELKKNEGGEKET---------GEITEEKSKQENEETSETNSKDK 325
E +N+ ++ +N+ KK EGG+ +T G+ E KQ+ + N K
Sbjct: 382 VEGAQNQGKKGEANQNQAKKGEGGQNQTKKGEGPQNQGKKGEAAQKQDKKIEGAQNQGKK 441
Query: 326 ENEESNQNGSDAKEQVGENHEQDSKQGTEETNGTEGGEKEEHDKIKEDTSSDNQVQDGE- 384
SNQ + GE + K+G N ++ GE + ++ K+ NQ + GE
Sbjct: 442 PEGTSNQG------KKGEGAQNQGKKGEGAQNQSKKGEGAQ-NQAKKGEGGQNQAKKGEG 494
Query: 385 -KNNEAREENYSGDNASSAVVDNKSQESSNKTEEQFDKKEKNEFELESQKNSNETTESTD 443
+N + E V N++++ + Q K E N+ + + + T+ +
Sbjct: 495 AQNQAKKGEGAQNQAKKGEGVQNQAKKGVEGAQNQGKKGEANQNQAKKGEGGQNQTKKGE 554
Query: 444 STITQNSQGNESEK-----DQAQTENDTPKGSASESDEQKQEQEQNNTTKDDVQTTDTSS 498
Q +G ++K + AQ + P+G++++ +K E QN K +
Sbjct: 555 GPQNQGKKGEAAQKQDKKIEGAQNQGKKPEGTSNQG--KKGEGAQNQGKKGEGAQNQGKK 612
Query: 499 QNGNDTTEKQNETSEDANSKKEDSSALNTTPNNEDSKSGVAGDQADSTTTTSSSETQDGN 558
G K+ E +++ K E + G G+ A + G
Sbjct: 613 GEGAQNQGKKGEGAQNQGKKGEGA-----------QNQGKKGEGAQNQGKKGEGAQNQGK 661
Query: 559 TNHGEYKDTTNENPEKNSGQ--EGTQESGSSSNTFDNKDAASNKVQLTTT--SDTSSEQK 614
G +N G+ EG Q G N+ + VQ + T ++ K
Sbjct: 662 KGEGPQNQAKKGEGAQNQGKKGEGAQNQGKKGEGAQNQGKKAEGVQSQSKKGEGTQNQGK 721
Query: 615 KDESSSAESK---SESSQNDNANSGQSNTTSDESANDNKDSSQVTTSSENSAEGNSNTEN 671
K + + + K S+QN ++ + T E ++ S+ + + AEG N
Sbjct: 722 KGDGNPNQGKKGEGASNQNRKTDTVANQGTKQEGVSNQVKKSEGSPNQGKKAEGAPNQGK 781
Query: 672 NSDENQNDSKNNENTNDSGNTSNDANVNENQNENAAQTKTSENEGDAQNESVESKK 727
D + + +K + + G S A + + + + A+ +S KK
Sbjct: 782 KKDGSPSQAKKVDAAANQGKKSEMAPAQGQKASMVQSQEAPKQDAPAKKKSGSRKK 837
Score = 100 bits (250), Expect = 1e-20
Identities = 102/537 (18%), Positives = 195/537 (35%), Gaps = 36/537 (6%)
Query: 261 QQENEENKDEEKSQQENEENKDEEKSQQENELKKNEGGEKETGEITEEKSKQENEETSET 320
Q + + + + E +N+ ++ +N+ KK EG + + K E +
Sbjct: 197 QGKKGQGAQNQAKKGEGAQNQGKKGEGAQNQAKKGEGAQNQA-------KKGEGAQNQGK 249
Query: 321 NSKDKENEESNQNGSDAKEQVGENHEQDSKQGTEETNGTEGGEKEEHDKIKEDTSSDNQV 380
+ +N+ G + + GE + K+G N + GE + ++ K+ + NQ
Sbjct: 250 KGEGAQNQAKKGEGGQNQAKKGEGAQNQGKKGEGAQNQGKKGEGAQ-NQAKKGEGAQNQA 308
Query: 381 QDGE-------KNNEAREENYSGDNASSAVVDNKSQESSNKTEEQFDKKEKNEFELESQK 433
+ GE K A+ ++ G+ A + + ++ K E + K ++Q
Sbjct: 309 KKGEGAQNQGKKGEGAQNQSKKGEGAQNQAKKGEGGQNQAKKGEGAQNQAKKGEGAQNQA 368
Query: 434 NSNETTESTDSTITQNSQGNESEKDQAQTENDTPKGSASESDEQKQEQEQNNTTKDD-VQ 492
E ++ + +Q N+ +K +A +N KG ++ +K E QN K + Q
Sbjct: 369 KKGEGVQNQAKKGVEGAQ-NQGKKGEA-NQNQAKKGEGGQNQTKKGEGPQNQGKKGEAAQ 426
Query: 493 TTDTSSQNGNDTTEKQNETSEDA-------NSKKEDSSALNTTPNNE----DSKSGVAGD 541
D + + +K TS N K+ A N + E +K G G
Sbjct: 427 KQDKKIEGAQNQGKKPEGTSNQGKKGEGAQNQGKKGEGAQNQSKKGEGAQNQAKKGEGGQ 486
Query: 542 QADSTTTTSSSETQDGNTNHGEYKDTTNENPEKNSGQEGTQESGSSSNTFDN--KDAASN 599
+ ++ + G + K + G EG Q G N K
Sbjct: 487 NQAKKGEGAQNQAKKGEGAQNQAKKGEGVQNQAKKGVEGAQNQGKKGEANQNQAKKGEGG 546
Query: 600 KVQLTTTSDTSSEQKKDESSSAESKS-ESSQNDNAN-SGQSNT-TSDESANDNKDSSQVT 656
+ Q ++ KK E++ + K E +QN G SN E A + +
Sbjct: 547 QNQTKKGEGPQNQGKKGEAAQKQDKKIEGAQNQGKKPEGTSNQGKKGEGAQNQGKKGEGA 606
Query: 657 TSSENSAEGNSNTENNSDENQNDSKNNENTNDSGNTSNDANVNENQNENAAQTKTSENEG 716
+ EG N + QN K E + G A N+ + AQ + + EG
Sbjct: 607 QNQGKKGEGAQNQGKKGEGAQNQGKKGEGAQNQGKKGEGAQ-NQGKKGEGAQNQGKKGEG 665
Query: 717 DAQNESVESKKENNESAHKDVDNNSNSNDQGSSDTSVTQDDKESRVDLGTLPESNGE 773
QN++ + + N+ + N +G+ + + +S+ G ++ G+
Sbjct: 666 -PQNQAKKGEGAQNQGKKGEGAQNQGKKGEGAQNQGKKAEGVQSQSKKGEGTQNQGK 721
Score = 97.1 bits (240), Expect = 2e-19
Identities = 118/576 (20%), Positives = 223/576 (38%), Gaps = 62/576 (10%)
Query: 39 GHSREQKASYGAST--KTGNEVVKLGRKDLKPRVEETSVIDARHKEDEEEADELDNKHDE 96
G + K GA K G G+K + + A+++ + E + K E
Sbjct: 263 GGQNQAKKGEGAQNQGKKGEGAQNQGKKGEGAQNQAKKGEGAQNQAKKGEGAQNQGKKGE 322
Query: 97 --QTKLDDVNGVEDNSEHKEDSVEQESE-ESSQNAKTDLEGEQHTEKVDEENDNAENKEN 153
Q + G ++ ++ E Q + E +QN EG Q+ K E N K
Sbjct: 323 GAQNQSKKGEGAQNQAKKGEGGQNQAKKGEGAQNQAKKGEGAQNQAKKGEGVQNQAKKGV 382
Query: 154 ESVE---KENEEIKKEVEDTETGESIEEKSHLENEESKETGEISEEKSHLE---NEESKE 207
E + K+ E + + + E G++ +K + K+ ++ +E N+ K
Sbjct: 383 EGAQNQGKKGEANQNQAKKGEGGQNQTKKGEGPQNQGKKGEAAQKQDKKIEGAQNQGKKP 442
Query: 208 TGESSEEKSHLENEESKETGESSEEKSH----LENEENKDE------EKSKQENEEIKDG 257
G S++ K + + GE ++ +S +N+ K E +K + + K G
Sbjct: 443 EGTSNQGKKGEGAQNQGKKGEGAQNQSKKGEGAQNQAKKGEGGQNQAKKGEGAQNQAKKG 502
Query: 258 EKIQQENEENK---DEEKSQQENEENKDEEKSQQENELKKNEGGEKET---------GEI 305
E Q + ++ + ++ K E +N+ ++ +N+ KK EGG+ +T G+
Sbjct: 503 EGAQNQAKKGEGVQNQAKKGVEGAQNQGKKGEANQNQAKKGEGGQNQTKKGEGPQNQGKK 562
Query: 306 TEEKSKQENEETSETNSKDKENEESNQN----GSDAKEQVGENHEQDSKQGTEETNGTEG 361
E KQ+ + N K SNQ G+ + + GE + K+G N +
Sbjct: 563 GEAAQKQDKKIEGAQNQGKKPEGTSNQGKKGEGAQNQGKKGEGAQNQGKKGEGAQNQGKK 622
Query: 362 GEKEEHDKIKEDTSSDNQVQDGEKNNEAREENYSGDNASSAVVDNKSQESSNKTEEQFDK 421
GE ++ K+ + NQ G+K A+ + G+ A + + ++ K E
Sbjct: 623 GEGAQNQG-KKGEGAQNQ---GKKGEGAQNQGKKGEGAQNQGKKGEGPQNQAKKGEGAQN 678
Query: 422 KEKNEFELESQKNSNETTESTDSTITQNSQGNESEKDQAQ-TENDTPKGSASESDEQKQE 480
+ K ++Q E ++ + ++G +S+ + + T+N KG + + +K E
Sbjct: 679 QGKKGEGAQNQGKKGEGAQNQG----KKAEGVQSQSKKGEGTQNQGKKGDGNPNQGKKGE 734
Query: 481 QEQNNTTKDDVQTTDTSSQNGNDTTEKQNETSEDANSKKEDSSALNTTPNNEDSKSGVAG 540
N K D + Q G K++E S + K E + PN K G
Sbjct: 735 GASNQNRKTDTVANQGTKQEGVSNQVKKSEGSPNQGKKAEGA------PNQGKKKDG--- 785
Query: 541 DQADSTTTTSSSETQDGNTNHGEYKDTTNENPEKNS 576
+ S ++ D N G+ + +K S
Sbjct: 786 -------SPSQAKKVDAAANQGKKSEMAPAQGQKAS 814
Score = 90.5 bits (223), Expect = 2e-17
Identities = 89/503 (17%), Positives = 180/503 (35%), Gaps = 34/503 (6%)
Query: 298 GEKETGEITEEKSKQ-ENEETSETNSKDKENEESNQNGSDAKEQVGENHEQDSKQGTEET 356
G K + T + K+ + + + +N+ G+ + + GE + +K+G
Sbjct: 186 GSKASSPATSSQGKKGQGAQNQAKKGEGAQNQGKKGEGAQNQAKKGEGAQNQAKKGEGAQ 245
Query: 357 NGTEGGEKEEHDKIKEDTSSDNQVQDGE-------KNNEAREENYSGDNASSAVVDNKSQ 409
N + GE + ++ K+ NQ + GE K A+ + G+ A + +
Sbjct: 246 NQGKKGEGAQ-NQAKKGEGGQNQAKKGEGAQNQGKKGEGAQNQGKKGEGAQNQAKKGEGA 304
Query: 410 ESSNKTEEQFDKKEKNEFELESQKNSNETTESTDSTITQNSQGNESEKDQAQTENDTPKG 469
++ K E + K E +N ++ E + + G K +N KG
Sbjct: 305 QNQAKKGEGAQNQGKKG---EGAQNQSKKGEGAQNQAKKGEGGQNQAKKGEGAQNQAKKG 361
Query: 470 SASESDEQKQEQEQNNTTKDDVQTTDTSSQNG--NDTTEKQNETSEDANSKKE---DSSA 524
+++ +K E QN K V+ + G N K+ E ++ K E +
Sbjct: 362 EGAQNQAKKGEGVQNQ-AKKGVEGAQNQGKKGEANQNQAKKGEGGQNQTKKGEGPQNQGK 420
Query: 525 LNTTPNNEDSKSGVAGDQADSTTTTSS-SETQDGNTNHGEYKDTTNENPEKNSGQEGTQE 583
+D K A +Q TS+ + +G N G+ + +K G + +
Sbjct: 421 KGEAAQKQDKKIEGAQNQGKKPEGTSNQGKKGEGAQNQGKKGEGAQNQSKKGEGAQNQAK 480
Query: 584 SG-----------SSSNTFDNKDAASNKVQLTTTSDTSSEQKKDESSSAESKSESSQND- 631
G + N + A N+ + +++ + + + K E++QN
Sbjct: 481 KGEGGQNQAKKGEGAQNQAKKGEGAQNQAKKGEGVQNQAKKGVEGAQNQGKKGEANQNQA 540
Query: 632 -NANSGQSNTTSDESANDNKDSSQVTTSSENSAEGNSNTENNSDENQNDSKNNENTNDSG 690
GQ+ T E + + + EG N + N K E + G
Sbjct: 541 KKGEGGQNQTKKGEGPQNQGKKGEAAQKQDKKIEGAQNQGKKPEGTSNQGKKGEGAQNQG 600
Query: 691 NTSNDANVNENQNENAAQTKTSENEGDAQNESVESKKENNESAHKDVDNNSNSNDQGSSD 750
A N+ + AQ + + EG AQN+ + + N+ + N +G+ +
Sbjct: 601 KKGEGAQ-NQGKKGEGAQNQGKKGEG-AQNQGKKGEGAQNQGKKGEGAQNQGKKGEGAQN 658
Query: 751 TSVTQDDKESRVDLGTLPESNGE 773
+ +++ G ++ G+
Sbjct: 659 QGKKGEGPQNQAKKGEGAQNQGK 681
Score = 75.5 bits (184), Expect = 5e-13
Identities = 83/465 (17%), Positives = 176/465 (37%), Gaps = 40/465 (8%)
Query: 39 GHSREQKASYGAS----TKTGNEVVKLGRKDLKPRVEETSVIDARHKEDEEEADELDNKH 94
G + + +A G TK G G+K + ++ + A+++ + E K
Sbjct: 392 GEANQNQAKKGEGGQNQTKKGEGPQNQGKKGEAAQKQDKKIEGAQNQGKKPEGTSNQGKK 451
Query: 95 DE--QTKLDDVNGVEDNSEHKEDSVEQESE-ESSQNAKTDLEGEQHTEKVDE-------E 144
E Q + G ++ S+ E + Q + E QN EG Q+ K E +
Sbjct: 452 GEGAQNQGKKGEGAQNQSKKGEGAQNQAKKGEGGQNQAKKGEGAQNQAKKGEGAQNQAKK 511
Query: 145 NDNAENKENESVE------KENEEIKKEVEDTETGESIEEKSHLENEESKETGEISEEKS 198
+ +N+ + VE K+ E + + + E G++ +K + K+ ++
Sbjct: 512 GEGVQNQAKKGVEGAQNQGKKGEANQNQAKKGEGGQNQTKKGEGPQNQGKKGEAAQKQDK 571
Query: 199 HLE---NEESKETGESSEEKSHLENEESKETGESSEEKSHLENEENKDEEKSKQENEEIK 255
+E N+ K G S++ K + + GE ++ + +K + + K
Sbjct: 572 KIEGAQNQGKKPEGTSNQGKKGEGAQNQGKKGEGAQNQGKKGEGAQNQGKKGEGAQNQGK 631
Query: 256 DGEKIQQENEENKDEEKSQQENE--ENKDEEKSQQENELKKNEGGEKETGEITEEKSKQE 313
GE Q + ++ + + ++ E +N+ ++ +N+ KK EG + + K E
Sbjct: 632 KGEGAQNQGKKGEGAQNQGKKGEGAQNQGKKGEGPQNQAKKGEGAQ-------NQGKKGE 684
Query: 314 NEETSETNSKDKENEESNQNGSDAKEQVGENHEQDSKQGTEETNGTEGGEKEEHDKIKED 373
+ + +N+ G ++ + GE + K+G N + GE + K D
Sbjct: 685 GAQNQGKKGEGAQNQGKKAEGVQSQSKKGEGTQNQGKKGDGNPNQGKKGEGASNQNRKTD 744
Query: 374 T-SSDNQVQDGEKNNEAREEN--YSGDNASSAVVDNKSQESSNKTEEQFDKKEKNEFELE 430
T ++ Q+G N + E G A A K ++ S ++ D +
Sbjct: 745 TVANQGTKQEGVSNQVKKSEGSPNQGKKAEGAPNQGKKKDGSPSQAKKVDAAAN-----Q 799
Query: 431 SQKNSNETTESTDSTITQNSQGNESEKDQAQTENDTPKGSASESD 475
+K+ + +++ Q+ + + + + KG D
Sbjct: 800 GKKSEMAPAQGQKASMVQSQEAPKQDAPAKKKSGSRKKGEPGPPD 844
Score = 55.8 bits (133), Expect = 4e-07
Identities = 118/607 (19%), Positives = 229/607 (37%), Gaps = 61/607 (10%)
Query: 176 IEEKSHLENEESKETGEISEEKSHLENEESKE-----TGESSEEKSHLENEESKETGESS 230
++EK L E ++ + L E + E GE+ +K + E+ ++
Sbjct: 905 LQEKEKLLATEQEDAAVAKSKLRELNKEMASEKAKAAAGEAKVKKQLVAREQEIAAVQAR 964
Query: 231 EEKSHLEN--EENKDEEKSKQENEEIKDGE-----KIQQENEENKD---EEKSQQENEEN 280
+ S+ ++ E + + K + E++++G ++QQEN +D + SQ E+++N
Sbjct: 965 MQASYRDHVKEVQQLQGKIRTLQEQLENGPNTQLARLQQENSILRDALNQATSQVESKQN 1024
Query: 281 KDEEKSQQENELKKNEGGEKETGEITEEKSKQENEETSETNSKD--------KENEESNQ 332
+ K +QE E EK EE+ ++ E + T K KE+EE+ Q
Sbjct: 1025 TELAKLRQELSKVNKELVEKSEASRQEEQQRKALEAKAATFEKQVLQLQASHKESEEALQ 1084
Query: 333 -------------NGSDAKEQVGENHEQDSKQGTEETNG-TEGGEKEEHDKIKEDTSSDN 378
S A + Q+ +Q E + + E E K +E +S
Sbjct: 1085 KRLEEVTRELCRAQTSHANLRADAEKAQEQQQRVAELHSKLQSSEVEVKSKCEELSSLHG 1144
Query: 379 QVQDGEKNNEAREENYSGDNASSAVVDNKSQESSNKTEEQFDKKEKNEFELESQKN--SN 436
Q+++ N E + A+++ + + + + ++++ ELESQ +
Sbjct: 1145 QLKEARAENSQLTERI---RSIEALLEAGQAQDTQASHAEANQQQTRLKELESQVSCLEK 1201
Query: 437 ETTESTDSTITQNSQGNE-SEKDQAQTENDTPKGSASE----SDEQKQEQEQNNTTKDDV 491
ET+E ++ Q + N+ EK+ E A E S Q +E+ + +
Sbjct: 1202 ETSELKEAMEQQKGKNNDLREKNWKAMEALALAERACEEKLRSLTQAKEESEKQLHLAEA 1261
Query: 492 QTTDT--SSQNGNDTTEKQNETSEDANSKKEDSSALNTTPNNEDSKSGVAG-DQADSTTT 548
QT +T + G + QN K++ S L P E S V +A+ T
Sbjct: 1262 QTKETLLALLPGLSISAHQNYAEWLQEFKEKGSELLKKPPTLEPSMDIVLKLREAEETQN 1321
Query: 549 TSSSETQDGNTNHGEYKDTTNENPEKNSGQEGTQESGSSSNTFDNKDAASNKVQLTTTSD 608
+ +E T E + + + +E ++ + ++ ++V + D
Sbjct: 1322 SLQAECDQYRTILAETEGMLKDLQKSVEEEERVWKAKVGA---AEEELHKSRVTVKHLED 1378
Query: 609 TSSEQKKDESSSAESKSESSQNDNANSGQSNTTSDESANDNKDSS---QVTTSSENSA-E 664
+ K + SS + + +S + S E N K+ + Q+ S++ E
Sbjct: 1379 IVEKLKGELESSDQVREHTSHLEAELEKHMAAASAECQNYAKEVAGLRQLLLESQSQLDE 1438
Query: 665 GNSNTENNSDE----NQNDSKNNENTNDSGNTSNDANVNENQNENAAQTKTSENEGDAQN 720
S + SDE Q S + D + A Q+ +T+ E +
Sbjct: 1439 AKSEAQKQSDELALVRQQLSDMRSHVEDGDVAGSPAVPPAEQDPMKLKTQLERTEATLEA 1498
Query: 721 ESVESKK 727
E +K
Sbjct: 1499 EQTRRQK 1505
Score = 55.5 bits (132), Expect = 5e-07
Identities = 124/608 (20%), Positives = 241/608 (39%), Gaps = 86/608 (14%)
Query: 45 KASYGASTKTGNEVVKLGRKDLKPRVEETSVIDA-RHKEDEEEADELDNKHDEQTKLDDV 103
+A+ +K E+ KL ++ K E +A R +E + +A E E+ L
Sbjct: 1014 QATSQVESKQNTELAKLRQELSKVNKELVEKSEASRQEEQQRKALEAKAATFEKQVLQLQ 1073
Query: 104 NGVEDNSEHKEDSVEQESEESSQNAKTDLEGEQHTEKVDEENDNAENKENESVEKENEEI 163
+++ E + +E+ + E + + EK E+ ++ ++ E+
Sbjct: 1074 ASHKESEEALQKRLEEVTRELCRAQTSHANLRADAEKAQEQQQRVAELHSK-LQSSEVEV 1132
Query: 164 KKEVEDTETGESIEEKSHLENEESKETGEISEEKSHLENEESKET----GESSEEKSHLE 219
K + E+ + +++ EN S+ T I ++ LE ++++T E++++++ L+
Sbjct: 1133 KSKCEELSSLHGQLKEARAEN--SQLTERIRSIEALLEAGQAQDTQASHAEANQQQTRLK 1190
Query: 220 NEES------KETGESSEEKSHLENEENKDEEKSKQENEEIKDGEKIQQENEENKDEEKS 273
ES KET E E + + N EK+ + E + E+ +E + + K
Sbjct: 1191 ELESQVSCLEKETSELKEAMEQQKGKNNDLREKNWKAMEALALAERACEEKLRSLTQAKE 1250
Query: 274 QQENEENKDEEKSQQ--------------ENELK-----KNEGGEKETGEITEEKSK--- 311
+ E + + E ++++ +N + K +G E T E S
Sbjct: 1251 ESEKQLHLAEAQTKETLLALLPGLSISAHQNYAEWLQEFKEKGSELLKKPPTLEPSMDIV 1310
Query: 312 ---QENEET---------------SETNSKDKENEESNQNGSDA-KEQVGENHEQDSK-- 350
+E EET +ET K+ ++S + K +VG E+ K
Sbjct: 1311 LKLREAEETQNSLQAECDQYRTILAETEGMLKDLQKSVEEEERVWKAKVGAAEEELHKSR 1370
Query: 351 ---QGTEETNGTEGGEKEEHDKIKEDTSS-DNQVQDGEKNNEAREENYSGDNAS--SAVV 404
+ E+ GE E D+++E TS + +++ A +NY+ + A ++
Sbjct: 1371 VTVKHLEDIVEKLKGELESSDQVREHTSHLEAELEKHMAAASAECQNYAKEVAGLRQLLL 1430
Query: 405 DNKSQESSNKTEEQFDKKEKNEFELESQKNSNETTESTDSTITQNSQGNESEKDQAQTEN 464
+++SQ K+E Q K+ +E L Q+ S+ + D + + +E+D + +
Sbjct: 1431 ESQSQLDEAKSEAQ---KQSDELALVRQQLSDMRSHVEDGDVAGSPAVPPAEQDPMKLKT 1487
Query: 465 DTPKGSASESDEQKQEQEQNNTTKDDVQTTDTSSQNGNDTTEKQNETSEDANSKKEDSSA 524
+ A+ EQ + Q+ ++ Q T Q + EK +S KE+ +
Sbjct: 1488 QLERTEATLEAEQTRRQKL-TAEFEEAQRTACRIQ---EELEKLRAAGPLESSGKEEITQ 1543
Query: 525 LNTTPNNEDSKSGVAGDQA----DSTTTTSSSETQDGNTNHGEYKDTTNENPEKNSGQEG 580
L E + G A + TT T++ KDT + E Q G
Sbjct: 1544 LKERLEKEKRLTSDLGRAAIKLQELLKTTQEQLTKE--------KDTVKKLQE----QLG 1591
Query: 581 TQESGSSS 588
E GSSS
Sbjct: 1592 KAEDGSSS 1599
Score = 49.7 bits (117), Expect = 3e-05
Identities = 37/181 (20%), Positives = 71/181 (38%), Gaps = 8/181 (4%)
Query: 609 TSSEQKKDESSSAESKS-ESSQNDN--ANSGQSNTTSDESANDNKDSSQVTTSSENSAEG 665
TSS+ KK + + ++K E +QN Q+ E A + + + EG
Sbjct: 194 TSSQGKKGQGAQNQAKKGEGAQNQGKKGEGAQNQAKKGEGAQNQAKKGEGAQNQGKKGEG 253
Query: 666 NSNTENNSDENQNDSKNNENTNDSGNTSNDANVNENQNENAAQTKTSENEGDAQNESVES 725
N + QN +K E + G A N+ + AQ + + EG AQN++ +
Sbjct: 254 AQNQAKKGEGGQNQAKKGEGAQNQGKKGEGAQ-NQGKKGEGAQNQAKKGEG-AQNQAKKG 311
Query: 726 KKENNESAHKDVDNNSNSNDQGSSDTSVTQDDKESRVDLGTLPES---NGESHHNDVSSA 782
+ N+ + N + +G+ + + + +++ G ++ GE N
Sbjct: 312 EGAQNQGKKGEGAQNQSKKGEGAQNQAKKGEGGQNQAKKGEGAQNQAKKGEGAQNQAKKG 371
Query: 783 E 783
E
Sbjct: 372 E 372
Score = 46.2 bits (108), Expect = 3e-04
Identities = 114/649 (17%), Positives = 238/649 (36%), Gaps = 91/649 (14%)
Query: 39 GHSREQKASYGAST--KTGNEVVKLGRKDLKPRVEETSVIDARHKEDEEEADELDNKHDE 96
G + K GA K G G+K + + A+++ + E + K E
Sbjct: 605 GAQNQGKKGEGAQNQGKKGEGAQNQGKKGEGAQNQGKKGEGAQNQGKKGEGAQNQGKKGE 664
Query: 97 --QTKLDDVNGVEDNSEHKEDSVEQESE-ESSQNAKTDLEGEQHTEKVDEENDNAENK-- 151
Q + G ++ + E + Q + E +QN EG Q K E N K
Sbjct: 665 GPQNQAKKGEGAQNQGKKGEGAQNQGKKGEGAQNQGKKAEGVQSQSKKGEGTQNQGKKGD 724
Query: 152 --ENESVEKENEEIKKEVEDTETGESIEEKSHLENEESKETGEISEEKSH--LENEESKE 207
N+ + E + DT + +++ + N+ K G ++ K N+ K+
Sbjct: 725 GNPNQGKKGEGASNQNRKTDTVANQGTKQEG-VSNQVKKSEGSPNQGKKAEGAPNQGKKK 783
Query: 208 TGESSEEK----SHLENEESKETGESSEEKSHLENEEN-KDEEKSKQENEEIKDGEK--- 259
G S+ K + + ++S+ ++ S ++++E K + +K+++ K GE
Sbjct: 784 DGSPSQAKKVDAAANQGKKSEMAPAQGQKASMVQSQEAPKQDAPAKKKSGSRKKGEPGPP 843
Query: 260 --------------------IQQENEENK-----DEEKSQQENEENKDEEKS-------Q 287
+ E E + E+ ++ +K +K +
Sbjct: 844 DCDGPLFLPYKTLVSTVGSMVFSEGEAQRLIEILSEKTGVIQDTWHKATQKGDPVAILKR 903
Query: 288 QENELKKNEGGEKETGEITEEKSKQENEETSETNSKDKENEESNQNGSDAKEQVGENHEQ 347
Q E +K E+E + + K ++ N+E + +K E + K+ V E
Sbjct: 904 QLQEKEKLLATEQEDAAVAKSKLRELNKEMASEKAKAAAGEAKVK-----KQLVAREQEI 958
Query: 348 DSKQGTEETNGTEGGEKEEHDKIKEDTSSDNQVQDGEKNNEAREENYSGDNASSAVVDNK 407
+ Q + + D +KE +++ +E+ +G N A + +
Sbjct: 959 AAVQARMQAS--------YRDHVKEVQQLQGKIR------TLQEQLENGPNTQLARLQQE 1004
Query: 408 S---QESSNKTEEQFDKKEKNE---FELESQKNSNETTESTDSTITQNSQGNESEKDQAQ 461
+ +++ N+ Q + K+ E E K + E E ++++ + Q E A
Sbjct: 1005 NSILRDALNQATSQVESKQNTELAKLRQELSKVNKELVEKSEASRQEEQQRKALEAKAAT 1064
Query: 462 TENDTPKGSASESDEQKQEQEQNNTTKDDVQTTDTSSQNGNDTTEKQNETSE---DANSK 518
E + AS + ++ Q++ ++ TS N EK E + + +SK
Sbjct: 1065 FEKQVLQLQASHKESEEALQKRLEEVTRELCRAQTSHANLRADAEKAQEQQQRVAELHSK 1124
Query: 519 KEDSSALNTTPNNEDSK--SGVAGDQADSTTTTSSSETQDGNTNHGEYKDTTNENPEKNS 576
+ S + E S + +A+++ T + + G+ +DT + E N
Sbjct: 1125 LQSSEVEVKSKCEELSSLHGQLKEARAENSQLTERIRSIEALLEAGQAQDTQASHAEANQ 1184
Query: 577 GQEGTQESGSSSNTFDNKDAASNKVQLTTTSDTSSEQKKDESSSAESKS 625
Q +E S + + + T+ + EQ+K +++ K+
Sbjct: 1185 QQTRLKELESQVSCLEKE---------TSELKEAMEQQKGKNNDLREKN 1224
>ATRX_CAEEL (Q9U7E0) Transcriptional regulator ATRX homolog
(X-linked nuclear protein-1)
Length = 1359
Score = 119 bits (297), Expect = 4e-26
Identities = 99/461 (21%), Positives = 222/461 (47%), Gaps = 27/461 (5%)
Query: 86 EADELDNKHDEQTKLDDVNGVEDNSEHKEDSVEQESEESSQNAKTDLEGEQHTEKVDEEN 145
E+++ D E L+ +E+ E KE ++ E+ + K + ++ +
Sbjct: 7 ESEDSDGHVIEDEDLEMARQIEN--ERKEKRAQKLKEKREREGKPPPKKRPAKKRKASSS 64
Query: 146 DNAENKENESVEKENEEIKKEVE-DTETGESIEEKSHLENEESKETGEISEEKSHLENE- 203
+ ++ E ES K +++ +K + ++E+ ES EE+ +++ K+ + +EKS +
Sbjct: 65 EEDDDDEEESPRKSSKKSRKRAKSESESDESDEEEDRKKSKSKKKVDQKKKEKSKKKRTT 124
Query: 204 ESKETGESSEEKSHLENEESKETGESSEEKSHLENEENKDEEKSKQENEEI--KDGEKIQ 261
S E +S EE+ ++SK+T + + +S E+EE + +KSK+ E+ K E +
Sbjct: 125 SSSEDEDSDEEREQKSKKKSKKTKKQTSSESSEESEEERKVKKSKKNKEKSVKKRAETSE 184
Query: 262 QENEENKDEEKSQ---QENEENKDEEKSQQENELKKNEGGEKETGEITEEKSKQENEETS 318
+ +E+ K +KS+ ++ +++ E +S+ E E+KK+ +K++ ++ +++S+ E+E
Sbjct: 185 ESDEDEKPSKKSKKGLKKKAKSESESESEDEKEVKKS---KKKSKKVVKKESESEDE--- 238
Query: 319 ETNSKDKENEESNQNGSDAKEQVGENHEQDSKQGTEETNGTEGGEKEEHDKIKEDTSSDN 378
+ +K+ E + + E+ E+ + D ++ EE + +K++ +K+ SSD
Sbjct: 239 ---APEKKKTEKRKRSKTSSEESSESEKSDEEE--EEKESSPKPKKKKPLAVKK-LSSDE 292
Query: 379 QVQDGEKNNEAREENYSGDNASSAVVDNKSQESSNKTEEQFDKKEKNEFELESQKNSNET 438
+ ++ + +++ S D K Q+S ++ + +K K + + Q++S
Sbjct: 293 ESEESDVEVLPQKKKRGAVTLISDSEDEKDQKSESEASDVEEKVSKK--KAKKQESSESG 350
Query: 439 TESTDSTITQNSQGNESEKDQAQTEN---DTPKGSASESDEQKQEQE-QNNTTKDDVQTT 494
++S++ +IT N + + EK + + + D+ K D ++ E+E + K +
Sbjct: 351 SDSSEGSITVNRKSKKKEKPEKKKKGIIMDSSKLQKETIDAERAEKERRKRLEKKQKEFN 410
Query: 495 DTSSQNGNDTTEKQNETSEDANSKKEDSSALNTTPNNEDSK 535
+ G D TE TS K ++T + E K
Sbjct: 411 GIVLEEGEDLTEMLTGTSSQRKLKSVVLDPDSSTVDEESKK 451
Score = 111 bits (278), Expect = 6e-24
Identities = 95/453 (20%), Positives = 203/453 (43%), Gaps = 41/453 (9%)
Query: 70 VEETSVIDARHKEDEEE---ADELDNKHDEQ-----TKLDDVNGVEDNSEHKEDSVEQES 121
+E+ + AR E+E + A +L K + + K +SE +D E+
Sbjct: 16 IEDEDLEMARQIENERKEKRAQKLKEKREREGKPPPKKRPAKKRKASSSEEDDDDEEESP 75
Query: 122 EESSQNAKTDLEGEQHTEKVDEENDNAENKENESVEKENEEIKKEVEDTETGE---SIEE 178
+SS+ ++ + E +++ DEE D ++K + V+++ +E K+ T + E S EE
Sbjct: 76 RKSSKKSRKRAKSESESDESDEEEDRKKSKSKKKVDQKKKEKSKKKRTTSSSEDEDSDEE 135
Query: 179 KSHLENEESKETGEISEEKSHLENEESK-----------------ETGESSEEKSHLENE 221
+ ++SK+T + + +S E+EE + ET E S+E +
Sbjct: 136 REQKSKKKSKKTKKQTSSESSEESEEERKVKKSKKNKEKSVKKRAETSEESDEDEKPSKK 195
Query: 222 ESKETGESSEEKSHLENEENKDEEKSKQENEEI--KDGEKIQQENEENKDEEK--SQQEN 277
K + ++ +S E+E+ K+ +KSK++++++ K+ E + E+ K E++ S+ +
Sbjct: 196 SKKGLKKKAKSESESESEDEKEVKKSKKKSKKVVKKESESEDEAPEKKKTEKRKRSKTSS 255
Query: 278 EENKDEEKSQQENELKKNEGGEKETGEITEEK--SKQENEETSETNSKDKENEESNQNGS 335
EE+ + EKS +E E K++ K+ + +K S +E+EE+ K+ + S
Sbjct: 256 EESSESEKSDEEEEEKESSPKPKKKKPLAVKKLSSDEESEESDVEVLPQKKKRGAVTLIS 315
Query: 336 DAKEQVGENHEQDSKQGTEETNGTEGGEKEEHDKIKEDTSSDNQVQDGEKNNEAREENYS 395
D++++ + E ++ E+ + + ++E + + + V K E E+
Sbjct: 316 DSEDEKDQKSESEASDVEEKVSKKKAKKQESSESGSDSSEGSITVNRKSKKKEKPEKKKK 375
Query: 396 GDNASSAVVDNKSQESSNKTEEQFDKKEKNEFELESQKNSNETTESTDSTITQNSQGNES 455
G ++D+ + E+ +K+ + E + QK N +T+ G S
Sbjct: 376 G-----IIMDSSKLQKETIDAERAEKERRKRLE-KKQKEFNGIVLEEGEDLTEMLTGTSS 429
Query: 456 EKDQAQTENDTPKGSASESDEQKQEQEQNNTTK 488
++ D P S + + +K + N+ +
Sbjct: 430 QRKLKSVVLD-PDSSTVDEESKKPVEVHNSLVR 461
Score = 103 bits (257), Expect = 2e-21
Identities = 100/434 (23%), Positives = 190/434 (43%), Gaps = 58/434 (13%)
Query: 37 QIGHSREQKASYGASTKTGNEVVKLGRKDLKPRVEETSVIDARHKEDEEEADELDNKHDE 96
QI + R++K + K E G+ K R + + ++D++E + +
Sbjct: 26 QIENERKEKRAQKLKEKRERE----GKPPPKKRPAKKRKASSSEEDDDDEEESPRKSSKK 81
Query: 97 QTKLDDVNGVEDNSEHKEDSVEQESEESSQNAKTDLEGEQHTEKVDEENDNAENKENESV 156
K D S+ +ED + +S++ K + ++ T E+ D+ E +E +S
Sbjct: 82 SRKRAKSESESDESDEEEDRKKSKSKKKVDQKKKEKSKKKRTTSSSEDEDSDEEREQKS- 140
Query: 157 EKENEEIKKEVEDTETGESIEEKSHLENEESKE--------TGEISEE------------ 196
+K++++ KK+ + ES EE+ +++++KE T E S+E
Sbjct: 141 KKKSKKTKKQTSSESSEESEEERKVKKSKKNKEKSVKKRAETSEESDEDEKPSKKSKKGL 200
Query: 197 ------KSHLENEESKETGESSEEKSHLENEESKETGESSEEK-------SHLENEENKD 243
+S E+E+ KE +S ++ + +ES+ E+ E+K S +EE+ +
Sbjct: 201 KKKAKSESESESEDEKEVKKSKKKSKKVVKKESESEDEAPEKKKTEKRKRSKTSSEESSE 260
Query: 244 EEKSKQENEEIKDGEKIQQENEENKDEEKSQQENEENKDEEKSQQ----------ENELK 293
EKS +E EE + K +++ + S +E+EE+ E Q+ ++E +
Sbjct: 261 SEKSDEEEEEKESSPKPKKKKPLAVKKLSSDEESEESDVEVLPQKKKRGAVTLISDSEDE 320
Query: 294 KNEGGEKETGEITEE--KSKQENEETSETNSKDKENEESNQNGSDAKEQVGENHE---QD 348
K++ E E ++ E+ K K + +E+SE+ S E + S KE+ + + D
Sbjct: 321 KDQKSESEASDVEEKVSKKKAKKQESSESGSDSSEGSITVNRKSKKKEKPEKKKKGIIMD 380
Query: 349 SKQGTEETNGTEGGEKEEHDKIKEDTSSDNQV--QDGEKNNEAREENYSGDNASSAVVDN 406
S + +ET E EKE ++++ N + ++GE E S S V+D
Sbjct: 381 SSKLQKETIDAERAEKERRKRLEKKQKEFNGIVLEEGEDLTEMLTGTSSQRKLKSVVLDP 440
Query: 407 KS---QESSNKTEE 417
S E S K E
Sbjct: 441 DSSTVDEESKKPVE 454
Score = 102 bits (255), Expect = 3e-21
Identities = 97/498 (19%), Positives = 202/498 (40%), Gaps = 57/498 (11%)
Query: 174 ESIEEKSHLENEESKETGEISEEKSHLENEESKETGESSEEKSHLENEESKETGESSEEK 233
ES + H+ +E E +ENE ++ + +EK E + + + + K
Sbjct: 7 ESEDSDGHVIEDEDLEMAR------QIENERKEKRAQKLKEKREREGKPPPKKRPAKKRK 60
Query: 234 SHLENEENKDEEKSKQENEEIKDGEKIQQENEENKDEEKSQQENEENKDEEKSQQENELK 293
+ E++ DEE+S +++ + K ++ + E+E ++ +E EE++ + KS+++ + K
Sbjct: 61 ASSSEEDDDDEEESPRKSSK-KSRKRAKSESESDESDE------EEDRKKSKSKKKVDQK 113
Query: 294 KNEGGEKETGEITEEKSKQENEETSETNSKDKENEESNQNGSDAKEQVGENHEQDSKQGT 353
K E +K+ T ++++E E SK K + Q S++ E+ +
Sbjct: 114 KKEKSKKK--RTTSSSEDEDSDEEREQKSKKKSKKTKKQTSSESSEE------------S 159
Query: 354 EETNGTEGGEKEEHDKIKEDTSSDNQVQDGEKNNEAREENYSGDNASSAVVDNKSQESSN 413
EE + +K + +K+ + + + EK ++ ++ S + +++ ++
Sbjct: 160 EEERKVKKSKKNKEKSVKKRAETSEESDEDEKPSKKSKKGLKKKAKSESESESEDEKEVK 219
Query: 414 KTEEQFDKKEKNEFELESQKNSNETTESTDSTITQNSQGNESEKDQAQTEN--DTPKGSA 471
K++++ K K E E E + + TE + T + + +ESEK + E +PK
Sbjct: 220 KSKKKSKKVVKKESESEDEAPEKKKTEKRKRSKTSSEESSESEKSDEEEEEKESSPKPKK 279
Query: 472 SESDEQKQEQEQNNTTKDDVQTTDTSSQNG-----NDTTEKQNETSEDANSKKEDSSALN 526
+ K+ + + DV+ + G +D+ +++++ SE S E+ +
Sbjct: 280 KKPLAVKKLSSDEESEESDVEVLPQKKKRGAVTLISDSEDEKDQKSESEASDVEEKVSKK 339
Query: 527 TTPNNEDSKSGVAGDQADSTTTTSSSETQDGNTNHGEYKDTTNENPEKNSGQEGTQESGS 586
E S+SG D ++ + T + K E PEK S
Sbjct: 340 KAKKQESSESG--SDSSEGSITVNR-------------KSKKKEKPEKKKKGIIMDSSKL 384
Query: 587 SSNTFDNKDAASNKVQLTTTSDTSSEQKKDESSSAESKSESSQNDNANSGQSNTTSDESA 646
T D + A + +KK + + E +G S+ +S
Sbjct: 385 QKETIDAERAEKER--------RKRLEKKQKEFNGIVLEEGEDLTEMLTGTSSQRKLKSV 436
Query: 647 NDNKDSSQVTTSSENSAE 664
+ DSS V S+ E
Sbjct: 437 VLDPDSSTVDEESKKPVE 454
Score = 84.0 bits (206), Expect = 1e-15
Identities = 73/425 (17%), Positives = 175/425 (41%), Gaps = 24/425 (5%)
Query: 340 QVGENHEQDSKQGTEETNGTEGGEKEEHDKIKEDTSSDNQVQDGEKNNEAREENYSGDNA 399
+VG + +DS E E + E+++ ++ + ++ E ++ A
Sbjct: 2 RVGVSESEDSDGHVIEDEDLEMARQIENERKEKRAQKLKEKREREGKPPPKKRPAKKRKA 61
Query: 400 SSAVVDNKSQESS-NKTEEQFDKKEKNEFELESQKNSNETTESTDSTITQNSQGNESEKD 458
SS+ D+ +E S K+ ++ K+ K+E E S+E+ E D +++ + + +K
Sbjct: 62 SSSEEDDDDEEESPRKSSKKSRKRAKSESE------SDESDEEEDRKKSKSKKKVDQKKK 115
Query: 459 QAQTENDTPKGSASESDEQKQEQEQNNTTKDDVQTTDTSSQNGNDTTEKQNETSEDANSK 518
+ + T S+SE ++ +E+EQ + K TSS++ ++ E++ N +
Sbjct: 116 EKSKKKRTT--SSSEDEDSDEEREQKSKKKSKKTKKQTSSESSEESEEERKVKKSKKNKE 173
Query: 519 KEDSSALNTTPNNEDSKSGVAGDQADSTTTTSSSETQDGNTNHGEYKDTTNENPEKNSGQ 578
K T+ +++ D+ S + + + + + E +D K +
Sbjct: 174 KSVKKRAETSEESDE-------DEKPSKKSKKGLKKKAKSESESESEDEKEVKKSKKKSK 226
Query: 579 EGTQESGSSSNTFDNKDAASNKVQLTTTSDTSSEQKKDESSSAESKSESSQNDNANSGQS 638
+ ++ S + K + + T+S+ SSE +K + E +S
Sbjct: 227 KVVKKESESEDEAPEKKKTEKRKRSKTSSEESSESEKSDEEEEEKESSPKPKKKKPLAVK 286
Query: 639 NTTSDESANDNKDSSQVTTSSENSAEGNSNTENNSDENQNDSKNNENTNDSGNTSNDANV 698
+SDE + + S V + G ++S+ D K+ ++ +++ + +
Sbjct: 287 KLSSDEES----EESDVEVLPQKKKRGAVTLISDSE----DEKDQKSESEASDVEEKVSK 338
Query: 699 NENQNENAAQTKTSENEGDAQNESVESKKENNESAHKDVDNNSNSNDQGSSDTSVTQDDK 758
+ + + ++++ + +EG KKE E K + +S+ + + D + ++
Sbjct: 339 KKAKKQESSESGSDSSEGSITVNRKSKKKEKPEKKKKGIIMDSSKLQKETIDAERAEKER 398
Query: 759 ESRVD 763
R++
Sbjct: 399 RKRLE 403
Score = 34.3 bits (77), Expect = 1.3
Identities = 25/132 (18%), Positives = 61/132 (45%), Gaps = 11/132 (8%)
Query: 425 NEFELESQKNSNETTESTDSTITQNSQGNESEKD---QAQTENDTPKGSASESDEQKQEQ 481
+E +E ++ E E ++ + G+ESE + ++ +E+D+ K SD++ +
Sbjct: 801 HEQRMERERVMREDAEE-EADFIDDGDGSESESEGSFKSGSESDSGKSVVLSSDDEGSSK 859
Query: 482 EQNNTTKDDVQTTDTSSQNGNDTTEKQNETSEDANSKKEDSSALNTTPNNEDSKSGVAGD 541
++ N K +++ T +++ S+D + + + +A+ + +AG+
Sbjct: 860 KKKNGNKPEIKKTAPQK-------KRKFLNSDDEDEEDGEDTAMAILQDGIRQSKRLAGE 912
Query: 542 QADSTTTTSSSE 553
+AD T + E
Sbjct: 913 EADLRDTDTPPE 924
Database: sprot
Posted date: Nov 25, 2004 10:54 AM
Number of letters in database: 59,974,054
Number of sequences in database: 164,201
Lambda K H
0.284 0.108 0.264
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 95,383,181
Number of Sequences: 164201
Number of extensions: 4811947
Number of successful extensions: 157573
Number of sequences better than 10.0: 5559
Number of HSP's better than 10.0 without gapping: 2366
Number of HSP's successfully gapped in prelim test: 3294
Number of HSP's that attempted gapping in prelim test: 23940
Number of HSP's gapped (non-prelim): 42492
length of query: 783
length of database: 59,974,054
effective HSP length: 118
effective length of query: 665
effective length of database: 40,598,336
effective search space: 26997893440
effective search space used: 26997893440
T: 11
A: 40
X1: 18 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 45 (21.6 bits)
S2: 70 (31.6 bits)
Medicago: description of AC141862.18