BLAST2 result
BLASTP 2.2.2 [Dec-14-2001]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= AC141436.1 + phase: 0
(324 letters)
Database: sprot
164,201 sequences; 59,974,054 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
DSOR_DROME (Q24324) Dual specificity mitogen-activated protein k... 187 3e-47
MPK1_XENLA (Q05116) Dual specificity mitogen-activated protein k... 175 2e-43
MPK1_SERCA (Q91447) Dual specificity mitogen-activated protein k... 174 2e-43
MPK1_RABIT (P29678) Dual specificity mitogen-activated protein k... 174 2e-43
MPK1_HUMAN (Q02750) Dual specificity mitogen-activated protein k... 174 4e-43
MPK1_RAT (Q01986) Dual specificity mitogen-activated protein kin... 173 5e-43
MPK1_MOUSE (P31938) Dual specificity mitogen-activated protein k... 173 5e-43
MPK1_PANTR (Q9XT09) Dual specificity mitogen-activated protein k... 172 1e-42
MPK1_CRIGR (Q63980) Dual specificity mitogen-activated protein k... 170 5e-42
MKK2_YEAST (P32491) MAP kinase kinase MKK2/SSP33 (EC 2.7.1.-) 166 7e-41
WIS1_SCHPO (P33886) Protein kinase wis1 (EC 2.7.1.-) (Protein ki... 163 5e-40
MPK5_RAT (Q62862) Dual specificity mitogen-activated protein kin... 163 5e-40
MPK2_CHICK (Q90891) Dual specificity mitogen-activated protein k... 162 8e-40
MPK2_RAT (P36506) Dual specificity mitogen-activated protein kin... 162 1e-39
MPK2_MOUSE (Q63932) Dual specificity mitogen-activated protein k... 162 1e-39
MPK2_CYPCA (Q90321) Dual specificity mitogen-activated protein k... 160 5e-39
MPK2_HUMAN (P36507) Dual specificity mitogen-activated protein k... 158 2e-38
MKK1_YEAST (P32490) MAP kinase kinase MKK1/SSP32 (EC 2.7.1.-) 157 3e-38
SKH1_SCHPO (Q9Y884) MAP kinase kinase skh1/pek1 (EC 2.7.1.-) 154 2e-37
MPK5_HUMAN (Q13163) Dual specificity mitogen-activated protein k... 154 2e-37
>DSOR_DROME (Q24324) Dual specificity mitogen-activated protein
kinase kinase dSOR1 (EC 2.7.1.-) (Downstream of RAF)
(MAPKK)
Length = 393
Score = 187 bits (475), Expect = 3e-47
Identities = 128/346 (36%), Positives = 179/346 (50%), Gaps = 57/346 (16%)
Query: 22 PRFPVPLPANIYKQPSTS--ATTASVAGGD--------------------NISAGDFEKL 59
P F P ++ +P TS A T ++ G D +S D EKL
Sbjct: 28 PPFKTPSGTDLLGKPKTSIDALTETLEGLDMGDTERKRIKMFLSQKEKIGELSDEDLEKL 87
Query: 60 SVLGHGNGGTVYKVRHKLTSIIYALKINHYDSDPTTRRRALTEVNILRRATDCTNVVKYH 119
LG GNGG V KVRH T +I A K+ H + P +++ L E+ +L + ++V ++
Sbjct: 88 GELGSGNGGVVMKVRHTHTHLIMARKLIHLEVKPAIKKQILRELKVLHEC-NFPHIVGFY 146
Query: 120 GSFEKPTGDVCILMEYMDSGSLETALKTTGTFSESKLSTVARDILNGLTYLHARN-IAHR 178
G+F G++ I MEYMD GSL+ LK G ES L + +L GL+YL + I HR
Sbjct: 147 GAFYS-DGEISICMEYMDGGSLDLILKRAGRIPESILGRITLAVLKGLSYLRDNHAIIHR 205
Query: 179 DIKPSNILVNIKNEVKIADFGVSKFMGRTLEA-CNSYVGTCAYMSPERFDPEVYGGNYNG 237
D+KPSNILVN E+KI DFGVS G+ +++ NS+VGT +YMSPER G +
Sbjct: 206 DVKPSNILVNSSGEIKICDFGVS---GQLIDSMANSFVGTRSYMSPERLQ-----GTHYS 257
Query: 238 FSADIWSLGLTLFELYVGYFPF----------------LQSGQRPDWASLMCAICFSD-- 279
+DIWSLGL+L E+ +G +P +SGQ D M D
Sbjct: 258 VQSDIWSLGLSLVEMAIGMYPIPPPNTATLESIFADNAEESGQPTDEPRAMAIFELLDYI 317
Query: 280 ----PPSLP-ETASSEFRNFVECCLKKESGERWSAAQLLTHPFLCK 320
PP L + S+EF++FV+ CLKK+ ER LL+HP++ K
Sbjct: 318 VNEPPPKLEHKIFSTEFKDFVDICLKKQPDERADLKTLLSHPWIRK 363
>MPK1_XENLA (Q05116) Dual specificity mitogen-activated protein
kinase kinase 1 (EC 2.7.1.-) (MAP kinase kinase 1)
(MAPKK 1) (ERK activator kinase 1) (MAPK/ERK kinase 1)
(MEK1)
Length = 394
Score = 175 bits (443), Expect = 2e-43
Identities = 113/307 (36%), Positives = 159/307 (50%), Gaps = 53/307 (17%)
Query: 55 DFEKLSVLGHGNGGTVYKVRHKLTSIIYALKINHYDSDPTTRRRALTEVNILRRATDCTN 114
DFEK+S LG GNGG V+KV HK TS+I A K+ H + P R + + E+ +L +
Sbjct: 66 DFEKVSELGAGNGGVVFKVSHKPTSLIMARKLIHLEIKPAIRNQIIRELQVLHEC-NSPY 124
Query: 115 VVKYHGSFEKPTGDVCILMEYMDSGSLETALKTTGTFSESKLSTVARDILNGLTYLHARN 174
+V ++G+F G++ I ME+MD GSL+ LK G E L V+ ++ GLTYL ++
Sbjct: 125 IVGFYGAFYS-DGEISICMEHMDGGSLDQVLKKAGKIPEKILGKVSIAVIKGLTYLREKH 183
Query: 175 -IAHRDIKPSNILVNIKNEVKIADFGVSKFMGRTLEA-CNSYVGTCAYMSPERFDPEVYG 232
I HRD+KPSNILVN + E+K+ DFGVS G+ +++ NS+VGT +YMSPER
Sbjct: 184 KIMHRDVKPSNILVNSRGEIKLCDFGVS---GQLIDSMANSFVGTRSYMSPERLQ----- 235
Query: 233 GNYNGFSADIWSLGLTLFELYVGYFPF--------------------------------- 259
G + +DIWS+GL+L E+ +G +P
Sbjct: 236 GTHYSVQSDIWSMGLSLVEMAIGRYPIPPPDAKELELIFGCSVERDPASSELAPRPRPPG 295
Query: 260 -----LQSGQRPDWA--SLMCAICFSDPPSLPE-TASSEFRNFVECCLKKESGERWSAAQ 311
RP A L+ I PP LP +EF++FV CL K ER Q
Sbjct: 296 RPISSYGPDSRPPMAIFELLDYIVNEPPPKLPSGVFGAEFQDFVNKCLVKNPAERADLKQ 355
Query: 312 LLTHPFL 318
L+ H F+
Sbjct: 356 LMVHSFI 362
>MPK1_SERCA (Q91447) Dual specificity mitogen-activated protein
kinase kinase 1 (EC 2.7.1.-) (MAP kinase kinase 1)
(MAPKK 1) (ERK activator kinase 1) (MAPK/ERK kinase 1)
(MEK1) (Fragment)
Length = 388
Score = 174 bits (442), Expect = 2e-43
Identities = 113/307 (36%), Positives = 159/307 (50%), Gaps = 53/307 (17%)
Query: 55 DFEKLSVLGHGNGGTVYKVRHKLTSIIYALKINHYDSDPTTRRRALTEVNILRRATDCTN 114
DFEK+S LG GNGG V+KV HK + +I A K+ H + P R + + E+ +L +
Sbjct: 60 DFEKISELGAGNGGVVFKVSHKPSGLIMARKLIHLEIKPAIRNQIIRELQVLHEC-NSPY 118
Query: 115 VVKYHGSFEKPTGDVCILMEYMDSGSLETALKTTGTFSESKLSTVARDILNGLTYLHARN 174
+V ++G+F G++ I ME+MD GSL+ LK G E L V+ ++ GLTYL ++
Sbjct: 119 IVGFYGAFYS-DGEISICMEHMDGGSLDQVLKKAGRIPEQILGKVSIAVIKGLTYLREKH 177
Query: 175 -IAHRDIKPSNILVNIKNEVKIADFGVSKFMGRTLEA-CNSYVGTCAYMSPERFDPEVYG 232
I HRD+KPSNILVN + E+K+ DFGVS G+ +++ NS+VGT +YMSPER
Sbjct: 178 KIMHRDVKPSNILVNSRGEIKLCDFGVS---GQLIDSMANSFVGTRSYMSPERLQ----- 229
Query: 233 GNYNGFSADIWSLGLTLFELYVGYFPF--------------------------------- 259
G + +DIWS+GL+L E+ +G +P
Sbjct: 230 GTHYSVQSDIWSMGLSLVEMAIGRYPIPPPDSKELELMFGCPVEGDSPVTETSPRQRAPG 289
Query: 260 -----LQSGQRPDWA--SLMCAICFSDPPSLPE-TASSEFRNFVECCLKKESGERWSAAQ 311
S RP A L+ I PP LP SEF++FV CL K ER Q
Sbjct: 290 RPMSSYGSDSRPPMAIFELLDYIVNEPPPKLPNGVFGSEFQDFVNKCLIKNPAERADLKQ 349
Query: 312 LLTHPFL 318
L+ H F+
Sbjct: 350 LMIHAFI 356
>MPK1_RABIT (P29678) Dual specificity mitogen-activated protein
kinase kinase 1 (EC 2.7.1.-) (MAP kinase kinase 1)
(MAPKK 1) (ERK activator kinase 1) (MAPK/ERK kinase 1)
(MEK1)
Length = 392
Score = 174 bits (442), Expect = 2e-43
Identities = 114/305 (37%), Positives = 160/305 (52%), Gaps = 51/305 (16%)
Query: 55 DFEKLSVLGHGNGGTVYKVRHKLTSIIYALKINHYDSDPTTRRRALTEVNILRRATDCTN 114
DFEK+S LG GNGG V+KV HK + ++ A K+ H + P R + + E+ +L +
Sbjct: 66 DFEKISELGAGNGGVVFKVSHKPSGLVMARKLIHLEIKPAIRNQIIRELQVLHEC-NSPY 124
Query: 115 VVKYHGSFEKPTGDVCILMEYMDSGSLETALKTTGTFSESKLSTVARDILNGLTYLHARN 174
+V ++G+F G++ I ME+MD GSL+ LK G E L V+ ++ GLTYL ++
Sbjct: 125 IVGFYGAFYS-DGEISICMEHMDGGSLDQVLKKAGRIPEQILGKVSIAVIKGLTYLREKH 183
Query: 175 -IAHRDIKPSNILVNIKNEVKIADFGVSKFMGRTLEA-CNSYVGTCAYMSPERFDPEVYG 232
I HRD+KPSNILVN + E+K+ DFGVS G+ +++ NS+VGT +YMSPER
Sbjct: 184 KIMHRDVKPSNILVNSRGEIKLCDFGVS---GQLIDSMANSFVGTRSYMSPERLQ----- 235
Query: 233 GNYNGFSADIWSLGLTLFELYVGYFPF---------LQSG-------------------- 263
G + +DIWS+GL+L E+ VG +P L G
Sbjct: 236 GTHYSVQSDIWSMGLSLVEMAVGRYPIPPPDAKELELMFGCQVEGDAAETPPRPRTPGRP 295
Query: 264 -------QRPDWA--SLMCAICFSDPPSLPETA-SSEFRNFVECCLKKESGERWSAAQLL 313
RP A L+ I PP LP S EF++FV CL K ER QL+
Sbjct: 296 LSSYGMDSRPPMAIFELLDYIVNEPPPKLPSAVFSLEFQDFVNKCLIKNPAERADLKQLM 355
Query: 314 THPFL 318
H F+
Sbjct: 356 VHAFI 360
>MPK1_HUMAN (Q02750) Dual specificity mitogen-activated protein
kinase kinase 1 (EC 2.7.1.-) (MAP kinase kinase 1)
(MAPKK 1) (ERK activator kinase 1) (MAPK/ERK kinase 1)
(MEK1)
Length = 392
Score = 174 bits (440), Expect = 4e-43
Identities = 114/305 (37%), Positives = 160/305 (52%), Gaps = 51/305 (16%)
Query: 55 DFEKLSVLGHGNGGTVYKVRHKLTSIIYALKINHYDSDPTTRRRALTEVNILRRATDCTN 114
DFEK+S LG GNGG V+KV HK + ++ A K+ H + P R + + E+ +L +
Sbjct: 66 DFEKISELGAGNGGVVFKVSHKPSGLVMARKLIHLEIKPAIRNQIIRELQVLHEC-NSPY 124
Query: 115 VVKYHGSFEKPTGDVCILMEYMDSGSLETALKTTGTFSESKLSTVARDILNGLTYLHARN 174
+V ++G+F G++ I ME+MD GSL+ LK G E L V+ ++ GLTYL ++
Sbjct: 125 IVGFYGAFYS-DGEISICMEHMDGGSLDQVLKKAGRIPEQILGKVSIAVIKGLTYLREKH 183
Query: 175 -IAHRDIKPSNILVNIKNEVKIADFGVSKFMGRTLEA-CNSYVGTCAYMSPERFDPEVYG 232
I HRD+KPSNILVN + E+K+ DFGVS G+ +++ NS+VGT +YMSPER
Sbjct: 184 KIMHRDVKPSNILVNSRGEIKLCDFGVS---GQLIDSMANSFVGTRSYMSPERLQ----- 235
Query: 233 GNYNGFSADIWSLGLTLFELYVGYFPF---------LQSG-------------------- 263
G + +DIWS+GL+L E+ VG +P L G
Sbjct: 236 GTHYSVQSDIWSMGLSLVEMAVGRYPIPPPDAKELELMFGCQVEGDAAETPPRPRTPGRP 295
Query: 264 -------QRPDWA--SLMCAICFSDPPSLPE-TASSEFRNFVECCLKKESGERWSAAQLL 313
RP A L+ I PP LP S EF++FV CL K ER QL+
Sbjct: 296 LSSYGMDSRPPMAIFELLDYIVNEPPPKLPSGVFSLEFQDFVNKCLIKNPAERADLKQLM 355
Query: 314 THPFL 318
H F+
Sbjct: 356 VHAFI 360
>MPK1_RAT (Q01986) Dual specificity mitogen-activated protein kinase
kinase 1 (EC 2.7.1.-) (MAP kinase kinase 1) (MAPKK 1)
(ERK activator kinase 1) (MAPK/ERK kinase 1) (MEK1)
Length = 392
Score = 173 bits (439), Expect = 5e-43
Identities = 114/305 (37%), Positives = 160/305 (52%), Gaps = 51/305 (16%)
Query: 55 DFEKLSVLGHGNGGTVYKVRHKLTSIIYALKINHYDSDPTTRRRALTEVNILRRATDCTN 114
DFEK+S LG GNGG V+KV HK + ++ A K+ H + P R + + E+ +L +
Sbjct: 66 DFEKISELGAGNGGVVFKVSHKPSGLVMARKLIHLEIKPAIRNQIIRELQVLHEC-NSPY 124
Query: 115 VVKYHGSFEKPTGDVCILMEYMDSGSLETALKTTGTFSESKLSTVARDILNGLTYLHARN 174
+V ++G+F G++ I ME+MD GSL+ LK G E L V+ ++ GLTYL ++
Sbjct: 125 IVGFYGAFYS-DGEISICMEHMDGGSLDQVLKKAGRIPEQILGKVSIAVIKGLTYLREKH 183
Query: 175 -IAHRDIKPSNILVNIKNEVKIADFGVSKFMGRTLEA-CNSYVGTCAYMSPERFDPEVYG 232
I HRD+KPSNILVN + E+K+ DFGVS G+ +++ NS+VGT +YMSPER
Sbjct: 184 KIMHRDVKPSNILVNSRGEIKLCDFGVS---GQLIDSMANSFVGTRSYMSPERLQ----- 235
Query: 233 GNYNGFSADIWSLGLTLFELYVGYFPF--------------------------------- 259
G + +DIWS+GL+L E+ VG +P
Sbjct: 236 GTHYSVQSDIWSMGLSLVEMAVGRYPIPPPDAKELELLFGCQVEGDAAETPPRPRTPGRP 295
Query: 260 LQS---GQRPDWA--SLMCAICFSDPPSLPE-TASSEFRNFVECCLKKESGERWSAAQLL 313
L S RP A L+ I PP LP S EF++FV CL K ER QL+
Sbjct: 296 LSSYGMDSRPPMAIFELLDYIVNEPPPKLPSGVFSLEFQDFVNKCLIKNPAERADLKQLM 355
Query: 314 THPFL 318
H F+
Sbjct: 356 VHAFI 360
>MPK1_MOUSE (P31938) Dual specificity mitogen-activated protein
kinase kinase 1 (EC 2.7.1.-) (MAP kinase kinase 1)
(MAPKK 1) (ERK activator kinase 1) (MAPK/ERK kinase 1)
(MEK1)
Length = 392
Score = 173 bits (439), Expect = 5e-43
Identities = 114/305 (37%), Positives = 160/305 (52%), Gaps = 51/305 (16%)
Query: 55 DFEKLSVLGHGNGGTVYKVRHKLTSIIYALKINHYDSDPTTRRRALTEVNILRRATDCTN 114
DFEK+S LG GNGG V+KV HK + ++ A K+ H + P R + + E+ +L +
Sbjct: 66 DFEKISELGAGNGGVVFKVSHKPSGLVMARKLIHLEIKPAIRNQIIRELQVLHEC-NSPY 124
Query: 115 VVKYHGSFEKPTGDVCILMEYMDSGSLETALKTTGTFSESKLSTVARDILNGLTYLHARN 174
+V ++G+F G++ I ME+MD GSL+ LK G E L V+ ++ GLTYL ++
Sbjct: 125 IVGFYGAFYS-DGEISICMEHMDGGSLDQVLKKAGRIPEQILGKVSIAVIKGLTYLREKH 183
Query: 175 -IAHRDIKPSNILVNIKNEVKIADFGVSKFMGRTLEA-CNSYVGTCAYMSPERFDPEVYG 232
I HRD+KPSNILVN + E+K+ DFGVS G+ +++ NS+VGT +YMSPER
Sbjct: 184 KIMHRDVKPSNILVNSRGEIKLCDFGVS---GQLIDSMANSFVGTRSYMSPERLQ----- 235
Query: 233 GNYNGFSADIWSLGLTLFELYVGYFPF--------------------------------- 259
G + +DIWS+GL+L E+ VG +P
Sbjct: 236 GTHYSVQSDIWSMGLSLVEMAVGRYPIPPPDAKELELLFGCHVEGDAAETPPRPRTPGRP 295
Query: 260 LQS---GQRPDWA--SLMCAICFSDPPSLPE-TASSEFRNFVECCLKKESGERWSAAQLL 313
L S RP A L+ I PP LP S EF++FV CL K ER QL+
Sbjct: 296 LSSYGMDSRPPMAIFELLDYIVNEPPPKLPSGVFSLEFQDFVNKCLIKNPAERADLKQLM 355
Query: 314 THPFL 318
H F+
Sbjct: 356 VHAFI 360
>MPK1_PANTR (Q9XT09) Dual specificity mitogen-activated protein
kinase kinase 1 (EC 2.7.1.-) (MAP kinase kinase 1)
(MAPKK 1) (ERK activator kinase 1) (MAPK/ERK kinase 1)
(MEK1)
Length = 392
Score = 172 bits (435), Expect = 1e-42
Identities = 113/305 (37%), Positives = 160/305 (52%), Gaps = 51/305 (16%)
Query: 55 DFEKLSVLGHGNGGTVYKVRHKLTSIIYALKINHYDSDPTTRRRALTEVNILRRATDCTN 114
DFEK+S LG GNGG V+KV HK + ++ A K+ H + P R + + E+ +L +
Sbjct: 66 DFEKISELGAGNGGVVFKVSHKPSGLVMARKLIHLEIKPAIRNQIIRELQVLHEC-NSPY 124
Query: 115 VVKYHGSFEKPTGDVCILMEYMDSGSLETALKTTGTFSESKLSTVARDILNGLTYLHARN 174
+V ++G+F G++ I ME+MD GSL+ LK G E L V+ ++ GLTYL ++
Sbjct: 125 IVGFYGAFYS-DGEISICMEHMDGGSLDQVLKKAGRIPEQILGKVSIAVIKGLTYLREKH 183
Query: 175 -IAHRDIKPSNILVNIKNEVKIADFGVSKFMGRTLEA-CNSYVGTCAYMSPERFDPEVYG 232
I HRD++PSNILVN + E+K+ DFGVS G+ +++ NS+VGT +YMSPERF
Sbjct: 184 KIMHRDVQPSNILVNSRGEIKLCDFGVS---GQLIDSMANSFVGTRSYMSPERFQ----- 235
Query: 233 GNYNGFSADIWSLGLTLFELYVGYFPF---------LQSG-------------------- 263
G + +DIWS+GL+ E+ VG +P L G
Sbjct: 236 GTHYSVQSDIWSMGLSPVEMAVGRYPIPSPDAKELELMFGCQVEGDAAETPPRPRTPGRP 295
Query: 264 -------QRPDWA--SLMCAICFSDPPSLPE-TASSEFRNFVECCLKKESGERWSAAQLL 313
RP A L+ I PP LP S EF++FV CL K ER QL+
Sbjct: 296 LSSYGMDSRPPMAIFELLDYIVNEPPPKLPSGVFSLEFQDFVNKCLIKNPAERADLKQLM 355
Query: 314 THPFL 318
H F+
Sbjct: 356 VHAFI 360
>MPK1_CRIGR (Q63980) Dual specificity mitogen-activated protein
kinase kinase 1 (EC 2.7.1.-) (MAP kinase kinase 1)
(MAPKK 1) (ERK activator kinase 1) (MAPK/ERK kinase 1)
(MEK1)
Length = 393
Score = 170 bits (430), Expect = 5e-42
Identities = 114/305 (37%), Positives = 158/305 (51%), Gaps = 51/305 (16%)
Query: 55 DFEKLSVLGHGNGGTVYKVRHKLTSIIYALKINHYDSDPTTRRRALTEVNILRRATDCTN 114
DFEK+S LG GNGG V+KV HK + ++ A K+ H + P R + + E+ +L +
Sbjct: 67 DFEKISELGAGNGGVVFKVSHKPSGLVMARKLIHLEIKPAIRNQIIRELQVLHEC-NSPY 125
Query: 115 VVKYHGSFEKPTGDVCILMEYMDSGSLETALKTTGTFSESKLSTVARDILNGLTYLHARN 174
+V ++G F G++ I ME+MD GSL+ LK G E L V+ ++ GLTYL ++
Sbjct: 126 IVGFYGVFYS-DGEISICMEHMDGGSLDQVLKKAGRIPEQILGKVSIAVIKGLTYLREKH 184
Query: 175 -IAHRDIKPSNILVNIKNEVKIADFGVSKFMGRTLEA-CNSYVGTCAYMSPERFDPEVYG 232
I HRD+KPSNILVN + E+K+ DFGVS G+ +++ NS+VGT +YMSPER
Sbjct: 185 KIMHRDVKPSNILVNSRGEIKLCDFGVS---GQLIDSMANSFVGTRSYMSPERLQ----- 236
Query: 233 GNYNGFSADIWSLGLTLFELYVGYFPF--------------------------------- 259
G + +DIWS+GL+L E+ VG +P
Sbjct: 237 GTHYSVQSDIWSMGLSLVEMAVGRYPIPPPDAKELELLFGCQVEGDAAETPPRPRTPGRP 296
Query: 260 LQS---GQRPDWA--SLMCAICFSDPPSLPE-TASSEFRNFVECCLKKESGERWSAAQLL 313
L S RP A L+ I P LP S EF++FV CL K ER QLL
Sbjct: 297 LSSYGMDSRPPMAIFELLDYIVNEPPAKLPSGVFSLEFQDFVNKCLIKNPAERADLKQLL 356
Query: 314 THPFL 318
H F+
Sbjct: 357 VHAFI 361
>MKK2_YEAST (P32491) MAP kinase kinase MKK2/SSP33 (EC 2.7.1.-)
Length = 506
Score = 166 bits (420), Expect = 7e-41
Identities = 109/282 (38%), Positives = 154/282 (53%), Gaps = 29/282 (10%)
Query: 59 LSVLGHGNGGTVYKVRHKLTSIIYALK-INHYDSDPTTRRRALTEVNILRRATDCTNVVK 117
L +LG G GG+V K R K ++ALK IN ++DP +++ E+ ++ +V+
Sbjct: 217 LGILGEGAGGSVAKCRLKNGKKVFALKTINTMNTDPEYQKQIFRELQF-NKSFKSDYIVQ 275
Query: 118 YHGSF-EKPTGDVCILMEYMDSGSLETA----LKTTGTFSESKLSTVARDILNGLTYLHA 172
Y+G F ++ + + I MEYM SLE LK G SE + +A +L GL+YLH
Sbjct: 276 YYGMFTDEQSSSIYIAMEYMGGKSLEATYKNLLKRGGRISERVIGKIAESVLRGLSYLHE 335
Query: 173 RNIAHRDIKPSNILVNIKNEVKIADFGVSKFMGRTLEACNS----YVGTCAYMSPERFDP 228
R + HRDIKP NIL+N K E+K+ DFGVS EA NS + GT YM+PER
Sbjct: 336 RKVIHRDIKPQNILLNEKGEIKLCDFGVSG------EAVNSLAMTFTGTSFYMAPERIQG 389
Query: 229 EVYGGNYNGFSADIWSLGLTLFELYVGYFPFLQSGQRPDWAS---LMCAICFS----DPP 281
+ Y + D+WSLGLTL E+ G FPF + A L + FS D P
Sbjct: 390 QPY-----SVTCDVWSLGLTLLEVAGGRFPFESDKITQNVAPIELLTMILTFSPQLKDEP 444
Query: 282 SLPETASSEFRNFVECCLKKESGERWSAAQLLTHPFLCKDME 323
L + S FR+F++ CLKK++ ER S Q+L HP++ M+
Sbjct: 445 ELDISWSKTFRSFIDYCLKKDARERPSPRQMLKHPWIVGQMK 486
>WIS1_SCHPO (P33886) Protein kinase wis1 (EC 2.7.1.-) (Protein
kinase sty2)
Length = 605
Score = 163 bits (413), Expect = 5e-40
Identities = 107/276 (38%), Positives = 150/276 (53%), Gaps = 15/276 (5%)
Query: 51 ISAGDFEKLSVLGHGNGGTVYKVRHKLTSIIYALKINHYDSDPTTRRRALTEVNILRRAT 110
I+ + KL LG GN G VYK H+ T + ALK + T + + E++IL +A
Sbjct: 315 INMSEIIKLEELGKGNYGVVYKALHQPTGVTMALKEIRLSLEEATFNQIIMELDILHKAV 374
Query: 111 DCTNVVKYHGSFEKPTGDVCILMEYMDSGSLETALKTTGTFSESKLSTVARDILNGL-TY 169
+V ++G+F G V I MEYMD+GS++ L G E L+ A ++ GL T
Sbjct: 375 S-PYIVDFYGAFFVE-GSVFICMEYMDAGSMDK-LYAGGIKDEGVLARTAYAVVQGLKTL 431
Query: 170 LHARNIAHRDIKPSNILVNIKNEVKIADFGVSKFMGRTLEACNSYVGTCAYMSPERFDPE 229
NI HRD+KP+N+LVN +VK+ DFGVS + ++ N +G +YM+PER
Sbjct: 432 KEEHNIIHRDVKPTNVLVNSNGQVKLCDFGVSGNLVASISKTN--IGCQSYMAPERIR-- 487
Query: 230 VYGGNYNGF-----SADIWSLGLTLFELYVGYFPFLQSGQRPDWASLMCAICFSDPPSLP 284
GG NG AD+WSLGLT+ E+ +G +P+ +A L AIC DPPSLP
Sbjct: 488 -VGGPTNGVLTYTVQADVWSLGLTILEMALGAYPYPPESYTSIFAQLS-AICDGDPPSLP 545
Query: 285 ETASSEFRNFVECCLKKESGERWSAAQLLTHPFLCK 320
++ S E R+FV CL K R +L HP+L K
Sbjct: 546 DSFSPEARDFVNKCLNKNPSLRPDYHELANHPWLLK 581
>MPK5_RAT (Q62862) Dual specificity mitogen-activated protein kinase
kinase 5 (EC 2.7.1.-) (MAP kinase kinase 5) (MAPKK 5)
(MAPK/ERK kinase 5)
Length = 448
Score = 163 bits (413), Expect = 5e-40
Identities = 107/296 (36%), Positives = 160/296 (53%), Gaps = 21/296 (7%)
Query: 28 LPANIYKQPSTSATTASVAGGDNISAGDFEKLSVLGHGNGGTVYKVRHKLTSIIYALKIN 87
LP+N K+ +SA + ++ D LGHGNGGTVYK H + I A+K+
Sbjct: 140 LPSNSLKK--SSAELRKILANGQMNEQDIRYRDTLGHGNGGTVYKAYHVPSGKILAVKVI 197
Query: 88 HYDSDPTTRRRALTEVNILRRATDCTNVVKYHGSFEKPTGDVCILMEYMDSGSLETALKT 147
D +++ ++E+ IL + D + ++ ++G+F + I E+MD GSL+ K
Sbjct: 198 LLDITLELQKQIMSELEILYKC-DSSYIIGFYGAFFVENR-ISICTEFMDGGSLDVYRK- 254
Query: 148 TGTFSESKLSTVARDILNGLTYLHARNIAHRDIKPSNILVNIKNEVKIADFGVSKFMGRT 207
E L +A ++ GLTYL + I HRD+KPSN+LVN +VK+ DFGVS + +
Sbjct: 255 ---IPEHVLGRIAVAVVKGLTYLWSLKILHRDVKPSNMLVNTSGQVKLCDFGVSTQLVNS 311
Query: 208 LEACNSYVGTCAYMSPERFDPEVYGGNYNGFSADIWSLGLTLFELYVGYFPFLQ----SG 263
+ +YVGT AYM+PER E Y G +D+WSLG++ EL +G FP+ Q G
Sbjct: 312 I--AKTYVGTNAYMAPERISGEQY-----GIHSDVWSLGISFMELALGRFPYPQIQKNQG 364
Query: 264 QRPDWASLMCAICFSDPPSLPETASSE-FRNFVECCLKKESGERWSAAQLLTHPFL 318
L C I D P LP SE F +F+ C++K+ ER + +L+ HPF+
Sbjct: 365 SLMPLQLLQC-IVDEDSPVLPLGEFSEPFVHFITQCMRKQPKERPAPEELMGHPFI 419
>MPK2_CHICK (Q90891) Dual specificity mitogen-activated protein
kinase kinase 2 (EC 2.7.1.-) (MAP kinase kinase 2)
(MAPKK 2) (ERK activator kinase 2) (MAPK/ERK kinase 2)
(MEK2)
Length = 398
Score = 162 bits (411), Expect = 8e-40
Identities = 108/309 (34%), Positives = 155/309 (49%), Gaps = 55/309 (17%)
Query: 55 DFEKLSVLGHGNGGTVYKVRHKLTSIIYALKINHYDSDPTTRRRALTEVNILRRATDCTN 114
DFE++S LG GNGG V KV+HK + +I A K+ H + P R + + E+ +L +
Sbjct: 69 DFERISELGAGNGGVVTKVQHKPSGLIMARKLIHLEIKPAIRNQIIRELQVLHEC-NSPY 127
Query: 115 VVKYHGSFEKPTGDVCILMEYMDSGSLETALKTTGTFSESKLSTVARDILNGLTYLHARN 174
+V ++G+F G++ I ME+MD GSL+ LK E L V+ +L GL YL ++
Sbjct: 128 IVGFYGAFYS-DGEISICMEHMDGGSLDQVLKEAKRIPEEILGKVSIAVLRGLAYLREKH 186
Query: 175 -IAHRDIKPSNILVNIKNEVKIADFGVSKFMGRTLEA-CNSYVGTCAYMSPERFDPEVYG 232
I HRD+KPSNILVN + E+K+ DFGVS G+ +++ NS+VGT +YMSPER
Sbjct: 187 QIMHRDVKPSNILVNSRGEIKLCDFGVS---GQLIDSMANSFVGTRSYMSPERLQ----- 238
Query: 233 GNYNGFSADIWSLGLTLFELYVGYFPFL---------------------QSGQRPDWA-- 269
G + +DIWS+GL+L EL +G +P +S WA
Sbjct: 239 GTHYSVQSDIWSMGLSLVELSIGRYPIPPPDSKELEAIFGRPVVDGAEGESHSVSPWARP 298
Query: 270 -------------------SLMCAICFSDPPSLPE-TASSEFRNFVECCLKKESGERWSA 309
L+ I PP LP + +F+ FV CL K ER
Sbjct: 299 PGRPISGHGMDSRPAMAIFELLDYIVNEPPPKLPNGVFTQDFQEFVNKCLIKNPAERADL 358
Query: 310 AQLLTHPFL 318
L+ H F+
Sbjct: 359 KMLMNHTFI 367
>MPK2_RAT (P36506) Dual specificity mitogen-activated protein kinase
kinase 2 (EC 2.7.1.-) (MAP kinase kinase 2) (MAPKK 2)
(ERK activator kinase 2) (MAPK/ERK kinase 2) (MEK2)
Length = 400
Score = 162 bits (409), Expect = 1e-39
Identities = 110/309 (35%), Positives = 156/309 (49%), Gaps = 55/309 (17%)
Query: 55 DFEKLSVLGHGNGGTVYKVRHKLTSIIYALKINHYDSDPTTRRRALTEVNILRRATDCTN 114
DFE++S LG GNGG V K RH+ + +I A K+ H + P R + + E+ +L +
Sbjct: 71 DFERISELGAGNGGVVTKARHRPSGLIMARKLIHLEIKPAVRNQIIRELQVLHEC-NSPY 129
Query: 115 VVKYHGSFEKPTGDVCILMEYMDSGSLETALKTTGTFSESKLSTVARDILNGLTYLHARN 174
+V ++G+F G++ I ME+MD GSL+ LK E L V+ +L GL YL ++
Sbjct: 130 IVGFYGAFYS-DGEISICMEHMDGGSLDQVLKEAKRIPEDILGKVSIAVLRGLAYLREKH 188
Query: 175 -IAHRDIKPSNILVNIKNEVKIADFGVSKFMGRTLEA-CNSYVGTCAYMSPERFDPEVYG 232
I HRD+KPSNILVN + E+K+ DFGVS G+ +++ NS+VGT +YMSPER
Sbjct: 189 QIMHRDVKPSNILVNSRGEIKLCDFGVS---GQLIDSMANSFVGTRSYMSPERLQ----- 240
Query: 233 GNYNGFSADIWSLGLTLFELYVGYFPF-------LQSG---------------------- 263
G + +DIWS+GL+L EL +G +P L++
Sbjct: 241 GTHYSVQSDIWSMGLSLVELAIGRYPIPPPDAKELEASFGRPVVDGADGEPHSVSPRPRP 300
Query: 264 -----------QRPDWA--SLMCAICFSDPPSLPE-TASSEFRNFVECCLKKESGERWSA 309
RP A L+ I PP LP SS+F+ FV CL K ER
Sbjct: 301 PGRPISGHGMDSRPAMAIFELLDYIVNEPPPKLPSGVFSSDFQEFVNKCLIKNPAERADL 360
Query: 310 AQLLTHPFL 318
L H F+
Sbjct: 361 KLLTNHAFI 369
>MPK2_MOUSE (Q63932) Dual specificity mitogen-activated protein
kinase kinase 2 (EC 2.7.1.-) (MAP kinase kinase 2)
(MAPKK 2) (ERK activator kinase 2) (MAPK/ERK kinase 2)
(MEK2)
Length = 401
Score = 162 bits (409), Expect = 1e-39
Identities = 110/310 (35%), Positives = 156/310 (49%), Gaps = 56/310 (18%)
Query: 55 DFEKLSVLGHGNGGTVYKVRHKLTSIIYALKINHYDSDPTTRRRALTEVNILRRATDCTN 114
DFE++S LG GNGG V K RH+ + I A K+ H + P R + + E+ +L +
Sbjct: 71 DFERISELGAGNGGVVTKARHRPSGFIMARKLIHLEIKPAVRNQIIRELQVLHEC-NSPY 129
Query: 115 VVKYHGSFEKPTGDVCILMEYMDSGSLETALKTTGTFSESKLSTVARDILNGLTYLHARN 174
+V ++G+F G++ I ME+MD GSL+ LK E L V+ +L GL YL ++
Sbjct: 130 IVGFYGAFYS-DGEISICMEHMDGGSLDQVLKEAKRIPEDILGKVSIAVLRGLAYLREKH 188
Query: 175 -IAHRDIKPSNILVNIKNEVKIADFGVSKFMGRTLEA-CNSYVGTCAYMSPERFDPEVYG 232
I HRD+KPSNILVN + E+K+ DFGVS G+ +++ NS+VGT +YMSPER
Sbjct: 189 QIMHRDVKPSNILVNSRGEIKLCDFGVS---GQLIDSMANSFVGTRSYMSPERLQ----- 240
Query: 233 GNYNGFSADIWSLGLTLFELYVGYFPF-------LQSG---------------------- 263
G + +DIWS+GL+L EL +G +P L++
Sbjct: 241 GTHYSVQSDIWSMGLSLVELAIGRYPIPPPDAKELEASFGRPVVDGADGEPHSVSPRPRP 300
Query: 264 ------------QRPDWA--SLMCAICFSDPPSLPE-TASSEFRNFVECCLKKESGERWS 308
RP A L+ I PP LP SS+F+ FV CL K ER
Sbjct: 301 PGRPISVGHGMDSRPAMAIFELLDYIVNEPPPKLPSGVFSSDFQEFVNKCLIKNPAERAD 360
Query: 309 AAQLLTHPFL 318
L+ H F+
Sbjct: 361 LKLLMNHAFI 370
>MPK2_CYPCA (Q90321) Dual specificity mitogen-activated protein
kinase kinase 2 (EC 2.7.1.-) (MAP kinase kinase 2)
(MAPKK 2) (ERK activator kinase 2) (MAPK/ERK kinase 2)
(MEK2)
Length = 397
Score = 160 bits (404), Expect = 5e-39
Identities = 105/309 (33%), Positives = 154/309 (48%), Gaps = 55/309 (17%)
Query: 55 DFEKLSVLGHGNGGTVYKVRHKLTSIIYALKINHYDSDPTTRRRALTEVNILRRATDCTN 114
DF+ + LG GNGG V+KVRHK + ++ A K+ H + P R + + E+ +L +
Sbjct: 68 DFDPICELGAGNGGVVHKVRHKPSRLVMARKLIHLEIKPAIRNQIIRELQVLHEC-NSPY 126
Query: 115 VVKYHGSFEKPTGDVCILMEYMDSGSLETALKTTGTFSESKLSTVARDILNGLTYLHARN 174
+V ++G+F G++ I ME+MD GSL+ LK E L V+ +L GL YL ++
Sbjct: 127 IVGFYGAFYS-DGEISICMEHMDGGSLDQVLKEARRIPEEILGKVSIAVLRGLVYLREKH 185
Query: 175 -IAHRDIKPSNILVNIKNEVKIADFGVSKFMGRTLEA-CNSYVGTCAYMSPERFDPEVYG 232
I HRD+KPSNILVN + E+K+ DFGVS G+ +++ NS+VGT +YMSPER
Sbjct: 186 QIMHRDVKPSNILVNSRGEIKLCDFGVS---GQLIDSMANSFVGTRSYMSPERLQ----- 237
Query: 233 GNYNGFSADIWSLGLTLFELYVGYFPF--------------------------LQSGQRP 266
G + +D+WS+GL+L EL +G FP + QRP
Sbjct: 238 GTHYSVQSDVWSMGLSLVELAIGRFPIPPPDAKELEAIFGRPVLDKGGAEGHSMSPRQRP 297
Query: 267 DWA----------------SLMCAICFSDPPSLPE-TASSEFRNFVECCLKKESGERWSA 309
L+ I PP LP +++F FV CL K +R
Sbjct: 298 PGRPVSGHGMDSRPAMAIFELLDYIVNEPPPKLPHGVFTTDFEEFVMKCLMKNPADRADL 357
Query: 310 AQLLTHPFL 318
L+ H F+
Sbjct: 358 KMLMGHTFI 366
>MPK2_HUMAN (P36507) Dual specificity mitogen-activated protein
kinase kinase 2 (EC 2.7.1.-) (MAP kinase kinase 2)
(MAPKK 2) (ERK activator kinase 2) (MAPK/ERK kinase 2)
(MEK2)
Length = 400
Score = 158 bits (400), Expect = 2e-38
Identities = 108/309 (34%), Positives = 156/309 (49%), Gaps = 55/309 (17%)
Query: 55 DFEKLSVLGHGNGGTVYKVRHKLTSIIYALKINHYDSDPTTRRRALTEVNILRRATDCTN 114
DFE++S LG GNGG V KV+H+ + +I A K+ H + P R + + E+ +L +
Sbjct: 71 DFERISELGAGNGGVVTKVQHRPSGLIMARKLIHLEIKPAIRNQIIRELQVLHEC-NSPY 129
Query: 115 VVKYHGSFEKPTGDVCILMEYMDSGSLETALKTTGTFSESKLSTVARDILNGLTYLHARN 174
+V ++G+F G++ I ME+MD GSL+ LK E L V+ +L GL YL ++
Sbjct: 130 IVGFYGAFYS-DGEISICMEHMDGGSLDQVLKEAKRIPEEILGKVSIAVLRGLAYLREKH 188
Query: 175 -IAHRDIKPSNILVNIKNEVKIADFGVSKFMGRTLEA-CNSYVGTCAYMSPERFDPEVYG 232
I HRD+KPSNILVN + E+K+ DFGVS G+ +++ NS+VGT +YM+PER
Sbjct: 189 QIMHRDVKPSNILVNSRGEIKLCDFGVS---GQLIDSMANSFVGTRSYMAPERLQ----- 240
Query: 233 GNYNGFSADIWSLGLTLFELYVGYFPF---------------LQSGQ------------- 264
G + +DIWS+GL+L EL VG +P + G+
Sbjct: 241 GTHYSVQSDIWSMGLSLVELAVGRYPIPPPDAKELEAIFGRPVVDGEEGEPHSISPRPRP 300
Query: 265 ------------RPDWA--SLMCAICFSDPPSLPE-TASSEFRNFVECCLKKESGERWSA 309
RP A L+ I PP LP + +F+ FV CL K ER
Sbjct: 301 PGRPVSGHGMDSRPAMAIFELLDYIVNEPPPKLPNGVFTPDFQEFVNKCLIKNPAERADL 360
Query: 310 AQLLTHPFL 318
L H F+
Sbjct: 361 KMLTNHTFI 369
>MKK1_YEAST (P32490) MAP kinase kinase MKK1/SSP32 (EC 2.7.1.-)
Length = 508
Score = 157 bits (397), Expect = 3e-38
Identities = 102/280 (36%), Positives = 150/280 (53%), Gaps = 21/280 (7%)
Query: 57 EKLSVLGHGNGGTVYKVRHKLTSIIYALK-INHYDSDPTTRRRALTEVNILRRATDCTNV 115
E L +LG G GG+V K + K S I+ALK IN ++DP +++ E+ R+ +
Sbjct: 222 ETLGILGEGAGGSVSKCKLKNGSKIFALKVINTLNTDPEYQKQIFRELQF-NRSFQSEYI 280
Query: 116 VKYHGSF-EKPTGDVCILMEYMDSGSLETALKTT----GTFSESKLSTVARDILNGLTYL 170
V+Y+G F + + I MEYM SL+ K G SE L +A +L GL+YL
Sbjct: 281 VRYYGMFTDDENSSIYIAMEYMGGRSLDAIYKNLLERGGRISEKVLGKIAEAVLRGLSYL 340
Query: 171 HARNIAHRDIKPSNILVNIKNEVKIADFGVSKFMGRTLEACNSYVGTCAYMSPERFDPEV 230
H + + HRDIKP NIL+N +VK+ DFGVS +L ++ GT YM+PER +
Sbjct: 341 HEKKVIHRDIKPQNILLNENGQVKLCDFGVSGEAVNSL--ATTFTGTSFYMAPERIQGQP 398
Query: 231 YGGNYNGFSADIWSLGLTLFELYVGYFPFLQSGQRPDWAS---LMCAICFS----DPPSL 283
Y ++D+WSLGLT+ E+ G FP + A LM + F+ D P
Sbjct: 399 Y-----SVTSDVWSLGLTILEVANGKFPCSSEKMAANIAPFELLMWILTFTPELKDEPES 453
Query: 284 PETASSEFRNFVECCLKKESGERWSAAQLLTHPFLCKDME 323
S F++F++ CLKK+S ER S Q++ HP++ M+
Sbjct: 454 NIIWSPSFKSFIDYCLKKDSRERPSPRQMINHPWIKGQMK 493
>SKH1_SCHPO (Q9Y884) MAP kinase kinase skh1/pek1 (EC 2.7.1.-)
Length = 363
Score = 154 bits (390), Expect = 2e-37
Identities = 103/278 (37%), Positives = 151/278 (54%), Gaps = 18/278 (6%)
Query: 51 ISAGDFEKLSVLGHGNGGTVYKVRHKLTSIIYALKINHYDSDPTTRRRALTEVNILRRAT 110
++ G ++ LG G G+V K R + T +I+A+K + +++ L E+ I R T
Sbjct: 74 VTNGGILYMNSLGEGVSGSVRKCRIRGTQMIFAMKTVLAAPNTALQKQLLRELKINRSCT 133
Query: 111 DCTNVVKYHGS-FEKPTGDVCILMEYMDSGSLETALKTT----GTFSESKLSTVARDILN 165
+VKY+G+ + + I MEY +GSL+ K G E L +A +L+
Sbjct: 134 S-PYIVKYYGACYNNAECQLNIAMEYCGAGSLDAIYKRVRSQGGRTGERPLGKIAFGVLS 192
Query: 166 GLTYLHARNIAHRDIKPSNILVNIKNEVKIADFGVSKFMGRTLEACNSYVGTCAYMSPER 225
GL+YLH R I HRDIKPSNIL+ K +VK+ DFGVS + +L ++ GT YM+PER
Sbjct: 193 GLSYLHDRKIIHRDIKPSNILLTSKGQVKLCDFGVSGELVNSL--AGTFTGTSYYMAPER 250
Query: 226 FDPEVYGGNYNGFSADIWSLGLTLFELYVGYFPFLQSGQRPDW-ASLMCAICFSDPPSLP 284
+ GG+Y S+DIWSLGLTL E+ + FPF G P L+ I PP LP
Sbjct: 251 ----ISGGSYT-ISSDIWSLGLTLMEVALNRFPFPPEGSPPPMPIELLSYIINMPPPLLP 305
Query: 285 ETA----SSEFRNFVECCLKKESGERWSAAQLLTHPFL 318
+ S F++F+ CL K+ R ++LTHP++
Sbjct: 306 QEPGIKWSKSFQHFLCVCLDKDKTRRPGPQKMLTHPWV 343
>MPK5_HUMAN (Q13163) Dual specificity mitogen-activated protein
kinase kinase 5 (EC 2.7.1.-) (MAP kinase kinase 5)
(MAPKK 5) (MAPK/ERK kinase 5)
Length = 438
Score = 154 bits (390), Expect = 2e-37
Identities = 102/292 (34%), Positives = 156/292 (52%), Gaps = 23/292 (7%)
Query: 28 LPANIYKQPSTSATTASVAGGDNISAGDFEKLSVLGHGNGGTVYKVRHKLTSIIYALKIN 87
LP+N K+ +SA + ++ D LGHGNGGTVYK H + I A+K+
Sbjct: 140 LPSNSLKK--SSAELKKILANGQMNEQDIRYRDTLGHGNGGTVYKAYHVPSGKILAVKVI 197
Query: 88 HYDSDPTTRRRALTEVNILRRATDCTNVVKYHGSFEKPTGDVCILMEYMDSGSLETALKT 147
D +++ ++E+ IL + D + ++ ++G+F + I E+MD GSL+ K
Sbjct: 198 LLDITLELQKQIMSELEILYKC-DSSYIIGFYGAFFVENR-ISICTEFMDGGSLDVYRK- 254
Query: 148 TGTFSESKLSTVARDILNGLTYLHARNIAHRDIKPSNILVNIKNEVKIADFGVSKFMGRT 207
E L +A ++ GLTYL + I HRD+KPSN+LVN + +VK+ DFGVS + +
Sbjct: 255 ---MPEHVLGRIAVAVVKGLTYLWSLKILHRDVKPSNMLVNTRGQVKLCDFGVSTQLVNS 311
Query: 208 LEACNSYVGTCAYMSPERFDPEVYGGNYNGFSADIWSLGLTLFELYVGYFPFLQSGQRPD 267
+ +YVGT AYM+PER E Y G +D+WSLG++ E+ Q P
Sbjct: 312 I--AKTYVGTNAYMAPERISGEQY-----GIHSDVWSLGISFMEIQKN-----QGSLMP- 358
Query: 268 WASLMCAICFSDPPSLPETASSE-FRNFVECCLKKESGERWSAAQLLTHPFL 318
L+ I D P LP SE F +F+ C++K+ ER + +L+ HPF+
Sbjct: 359 -LQLLQCIVDEDSPVLPVGEFSEPFVHFITQCMRKQPKERPAPEELMGHPFI 409
Database: sprot
Posted date: Nov 25, 2004 10:54 AM
Number of letters in database: 59,974,054
Number of sequences in database: 164,201
Lambda K H
0.319 0.135 0.410
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 40,242,414
Number of Sequences: 164201
Number of extensions: 1738044
Number of successful extensions: 8215
Number of sequences better than 10.0: 1702
Number of HSP's better than 10.0 without gapping: 1556
Number of HSP's successfully gapped in prelim test: 146
Number of HSP's that attempted gapping in prelim test: 4018
Number of HSP's gapped (non-prelim): 1947
length of query: 324
length of database: 59,974,054
effective HSP length: 110
effective length of query: 214
effective length of database: 41,911,944
effective search space: 8969156016
effective search space used: 8969156016
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 66 (30.0 bits)
Medicago: description of AC141436.1