BLAST2 result
BLASTP 2.2.2 [Dec-14-2001]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= AC140916.2 + phase: 0
(413 letters)
Database: sprot
164,201 sequences; 59,974,054 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
HEM2_PEA (P30124) Delta-aminolevulinic acid dehydratase, chlorop... 750 0.0
HEM2_SOYBN (P43210) Delta-aminolevulinic acid dehydratase, chlor... 716 0.0
HEM2_ARATH (Q9SFH9) Delta-aminolevulinic acid dehydratase, chlor... 662 0.0
HEM2_SPIOL (P24493) Delta-aminolevulinic acid dehydratase, chlor... 642 0.0
HEM2_HORVU (Q42836) Delta-aminolevulinic acid dehydratase, chlor... 585 e-167
HEM2_SELMA (P45623) Delta-aminolevulinic acid dehydratase, chlor... 573 e-163
HEM2_PHYPA (Q43058) Delta-aminolevulinic acid dehydratase, chlor... 562 e-160
HEM2_CHLRE (Q42682) Delta-aminolevulinic acid dehydratase, chlor... 434 e-121
HEM2_CHLTE (Q8KCJ0) Delta-aminolevulinic acid dehydratase (EC 4.... 333 6e-91
HEM2_CHLVI (Q59334) Delta-aminolevulinic acid dehydratase (EC 4.... 332 1e-90
HEM2_BACHD (Q9K8G2) Delta-aminolevulinic acid dehydratase (EC 4.... 295 2e-79
HEM2_AQUAE (O67876) Delta-aminolevulinic acid dehydratase (EC 4.... 294 2e-79
HEM2_BRAJA (P45622) Delta-aminolevulinic acid dehydratase (EC 4.... 291 2e-78
HEM2_RHOCA (P42504) Delta-aminolevulinic acid dehydratase (EC 4.... 288 2e-77
HEM2_BACSU (P30950) Delta-aminolevulinic acid dehydratase (EC 4.... 286 9e-77
HEM2_SYNP7 (P43087) Delta-aminolevulinic acid dehydratase (EC 4.... 284 3e-76
HEM2_METJA (Q60178) Delta-aminolevulinic acid dehydratase (EC 4.... 283 4e-76
HEM2_METSC (Q02250) Delta-aminolevulinic acid dehydratase (EC 4.... 282 1e-75
HEM2_ECOLI (P15002) Delta-aminolevulinic acid dehydratase (EC 4.... 280 5e-75
HEM2_CHLPN (Q9Z7G1) Delta-aminolevulinic acid dehydratase (EC 4.... 280 6e-75
>HEM2_PEA (P30124) Delta-aminolevulinic acid dehydratase,
chloroplast precursor (EC 4.2.1.24) (Porphobilinogen
synthase) (ALADH) (Fragment)
Length = 398
Score = 750 bits (1936), Expect = 0.0
Identities = 375/398 (94%), Positives = 384/398 (96%), Gaps = 1/398 (0%)
Query: 17 HTYVDLKPALPLKNYLSFSSSKRR-PPCLFTVRASDADFEAAVVAGNVPDAPPVPPTPAA 75
HT+VDLK L NYLSFSSSKRR PP LFTVRASD+DFEAAVVAG VP+APPVPPTPA+
Sbjct: 1 HTFVDLKSPFTLSNYLSFSSSKRRQPPSLFTVRASDSDFEAAVVAGKVPEAPPVPPTPAS 60
Query: 76 PAGTPVVTSLPIQRRPRRNRRSATHRSAFQETTLSPANFVYPLFIHEGEEDTPIGAMPGC 135
PAGTPVV SLPIQRRPRRNRRS RSAFQETTLSPANFVYPLFIHEGEEDTPIGAMPGC
Sbjct: 61 PAGTPVVPSLPIQRRPRRNRRSPALRSAFQETTLSPANFVYPLFIHEGEEDTPIGAMPGC 120
Query: 136 YRLGWRHGLIEEVAKARDVGVNSVVLFPKIPDALKTPTGDEAYNENGLVPRTIRLLKDKY 195
YRLGWRHGL+EEVAKARDVGVNSVVLFPKIPDALKTPTGDEAYNE+GLVPR+IRLLKDKY
Sbjct: 121 YRLGWRHGLLEEVAKARDVGVNSVVLFPKIPDALKTPTGDEAYNEDGLVPRSIRLLKDKY 180
Query: 196 PDLVIYTDVALDPYSSDGHDGIVREDGVIMNDETVHQLCKQAVAQARAGADVVSPSDMMD 255
PDL+IYTDVALDPYSSDGHDGIVREDGVIMNDETVHQLCKQAVAQARAGADVVSPSDMMD
Sbjct: 181 PDLIIYTDVALDPYSSDGHDGIVREDGVIMNDETVHQLCKQAVAQARAGADVVSPSDMMD 240
Query: 256 GRVGAMRAALDAEGFQHVSIMSYTAKYASSFYGPFREALDSNPRFGDKKTYQMNPANYRE 315
GRVGAMR ALDAEGFQHVSIMSYTAKYASSFYGPFREALDSNPRFGDKKTYQMNPANYRE
Sbjct: 241 GRVGAMRVALDAEGFQHVSIMSYTAKYASSFYGPFREALDSNPRFGDKKTYQMNPANYRE 300
Query: 316 ALTEMREDETEGADILLVKPGLPYLDIIRLLRDNSPLPIAAYQVSGEYSMIKAGGALKMI 375
ALTEMREDE+EGADILLVKPGLPYLDIIRLLRDNSPLPIAAYQVSGEYSMIKAGGALKMI
Sbjct: 301 ALTEMREDESEGADILLVKPGLPYLDIIRLLRDNSPLPIAAYQVSGEYSMIKAGGALKMI 360
Query: 376 DEEKVMMESLLCLRRAGADIILTYFALQAARCLCGEKR 413
DEEKVMMESLLCLRRAGADIILTYFALQAAR LCGEKR
Sbjct: 361 DEEKVMMESLLCLRRAGADIILTYFALQAARTLCGEKR 398
>HEM2_SOYBN (P43210) Delta-aminolevulinic acid dehydratase,
chloroplast precursor (EC 4.2.1.24) (Porphobilinogen
synthase) (ALADH)
Length = 412
Score = 716 bits (1847), Expect = 0.0
Identities = 359/411 (87%), Positives = 379/411 (91%), Gaps = 1/411 (0%)
Query: 4 SSTIPNTPLTLNSHTYVDLKPALPLKNYLSFSSSK-RRPPCLFTVRASDADFEAAVVAGN 62
+S+IPN P NS +YV L+ L N+ S ++K R LF VRASD++FEAAVVAG
Sbjct: 2 ASSIPNAPSAFNSQSYVGLRAPLRTFNFSSPQAAKIPRSQRLFVVRASDSEFEAAVVAGK 61
Query: 63 VPDAPPVPPTPAAPAGTPVVTSLPIQRRPRRNRRSATHRSAFQETTLSPANFVYPLFIHE 122
VP APPV P PAAP GTPVV SLP+ RRPRRNR+S RSAFQET++SPANFVYPLFIHE
Sbjct: 62 VPPAPPVRPRPAAPVGTPVVPSLPLHRRPRRNRKSPALRSAFQETSISPANFVYPLFIHE 121
Query: 123 GEEDTPIGAMPGCYRLGWRHGLIEEVAKARDVGVNSVVLFPKIPDALKTPTGDEAYNENG 182
GEEDTPIGAMPGCYRLGWRHGL+EEVAKARDVGVNSVVLFPKIPDALK+PTGDEAYNENG
Sbjct: 122 GEEDTPIGAMPGCYRLGWRHGLVEEVAKARDVGVNSVVLFPKIPDALKSPTGDEAYNENG 181
Query: 183 LVPRTIRLLKDKYPDLVIYTDVALDPYSSDGHDGIVREDGVIMNDETVHQLCKQAVAQAR 242
LVPRTIRLLKDKYPDLVIYTDVALDPYSSDGHDGIVREDGVIMNDETVHQLCKQAVAQA+
Sbjct: 182 LVPRTIRLLKDKYPDLVIYTDVALDPYSSDGHDGIVREDGVIMNDETVHQLCKQAVAQAQ 241
Query: 243 AGADVVSPSDMMDGRVGAMRAALDAEGFQHVSIMSYTAKYASSFYGPFREALDSNPRFGD 302
AGADVVSPSDMMDGRVGA+RAALDAEGFQHVSIMSYTAKYASSFYGPFREALDSNPRFGD
Sbjct: 242 AGADVVSPSDMMDGRVGALRAALDAEGFQHVSIMSYTAKYASSFYGPFREALDSNPRFGD 301
Query: 303 KKTYQMNPANYREALTEMREDETEGADILLVKPGLPYLDIIRLLRDNSPLPIAAYQVSGE 362
KKTYQMNPANYREALTEMREDE+EGADILLVKPGLPYLDIIRLLRDNSPLPIAAYQVSGE
Sbjct: 302 KKTYQMNPANYREALTEMREDESEGADILLVKPGLPYLDIIRLLRDNSPLPIAAYQVSGE 361
Query: 363 YSMIKAGGALKMIDEEKVMMESLLCLRRAGADIILTYFALQAARCLCGEKR 413
Y+MIKA GALKMIDEEKVMMESL+CLRRAGADIILTY ALQAARCLCGEKR
Sbjct: 362 YAMIKAAGALKMIDEEKVMMESLMCLRRAGADIILTYSALQAARCLCGEKR 412
>HEM2_ARATH (Q9SFH9) Delta-aminolevulinic acid dehydratase,
chloroplast precursor (EC 4.2.1.24) (Porphobilinogen
synthase) (ALADH)
Length = 430
Score = 662 bits (1707), Expect = 0.0
Identities = 323/364 (88%), Positives = 342/364 (93%)
Query: 50 SDADFEAAVVAGNVPDAPPVPPTPAAPAGTPVVTSLPIQRRPRRNRRSATHRSAFQETTL 109
SDA+ EAAV AGNVP+APPVPP PAAP GTP++ L + RRPRRNR S R+AFQET +
Sbjct: 67 SDAECEAAVAAGNVPEAPPVPPKPAAPVGTPIIKPLNLSRRPRRNRASPVTRAAFQETDI 126
Query: 110 SPANFVYPLFIHEGEEDTPIGAMPGCYRLGWRHGLIEEVAKARDVGVNSVVLFPKIPDAL 169
SPANFVYPLFIHEGEEDTPIGAMPGCYRLGWRHGL++EVAKAR VGVNS+VLFPK+P+AL
Sbjct: 127 SPANFVYPLFIHEGEEDTPIGAMPGCYRLGWRHGLVQEVAKARAVGVNSIVLFPKVPEAL 186
Query: 170 KTPTGDEAYNENGLVPRTIRLLKDKYPDLVIYTDVALDPYSSDGHDGIVREDGVIMNDET 229
K TGDEAYN+NGLVPRTIRLLKDKYPDL+IYTDVALDPYSSDGHDGIVREDGVIMNDET
Sbjct: 187 KNSTGDEAYNDNGLVPRTIRLLKDKYPDLIIYTDVALDPYSSDGHDGIVREDGVIMNDET 246
Query: 230 VHQLCKQAVAQARAGADVVSPSDMMDGRVGAMRAALDAEGFQHVSIMSYTAKYASSFYGP 289
VHQLCKQAV+QARAGADVVSPSDMMDGRVGA+R+ALDAEGFQ+VSIMSYTAKYASSFYGP
Sbjct: 247 VHQLCKQAVSQARAGADVVSPSDMMDGRVGAIRSALDAEGFQNVSIMSYTAKYASSFYGP 306
Query: 290 FREALDSNPRFGDKKTYQMNPANYREALTEMREDETEGADILLVKPGLPYLDIIRLLRDN 349
FREALDSNPRFGDKKTYQMNPANYREAL E REDE EGADILLVKPGLPYLDIIRLLRD
Sbjct: 307 FREALDSNPRFGDKKTYQMNPANYREALIEAREDEAEGADILLVKPGLPYLDIIRLLRDK 366
Query: 350 SPLPIAAYQVSGEYSMIKAGGALKMIDEEKVMMESLLCLRRAGADIILTYFALQAARCLC 409
SPLPIAAYQVSGEYSMIKAGG LKMIDEEKVMMESL+CLRRAGADIILTYFALQAA CLC
Sbjct: 367 SPLPIAAYQVSGEYSMIKAGGVLKMIDEEKVMMESLMCLRRAGADIILTYFALQAATCLC 426
Query: 410 GEKR 413
GEKR
Sbjct: 427 GEKR 430
>HEM2_SPIOL (P24493) Delta-aminolevulinic acid dehydratase,
chloroplast precursor (EC 4.2.1.24) (Porphobilinogen
synthase) (ALADH) (ALAD)
Length = 433
Score = 642 bits (1657), Expect = 0.0
Identities = 335/434 (77%), Positives = 359/434 (82%), Gaps = 22/434 (5%)
Query: 1 MASSSTIPNTPLTL----NSHTYVDLKPALPL---KNYLSFSSSKRRPPCLFTVRASDA- 52
MAS+ IP T+ NS + L + K S R P VRAS+
Sbjct: 1 MASTFNIPCNAGTIKNFNNSQRNLGFSSNLGINFAKTRFSNCGDSGRIPSQLVVRASERR 60
Query: 53 -------------DFEAAVVAGNVPDAPPVPPTPAAPAGTPVVTSLPIQRRPRRNRRSAT 99
+ EAAVVAGN P APPVPPTP AP+GTP V+ L + RRPRRNR S
Sbjct: 61 DNLTQQKTGLSIEECEAAVVAGNAPSAPPVPPTPKAPSGTPSVSPLSLGRRPRRNRTSPV 120
Query: 100 HRSAFQETTLSPANFVYPLFIHEGEEDTPIGAMPGCYRLGWRHGLIEEVAKARDVGVNSV 159
R+AFQETTLSPAN VYPLFIHEGEEDTPIGAMPGCYRLGWRHGL+EEVAKARDV VNS+
Sbjct: 121 FRAAFQETTLSPANVVYPLFIHEGEEDTPIGAMPGCYRLGWRHGLVEEVAKARDVVVNSI 180
Query: 160 VLFPKIPDALKTPTGDEAYNENGLVPRTIRLLKDKYPDLVIYTDVALDPYSSDGHDGIVR 219
V+FPK PDALK+PTGDEAYNENGLVPRTIR+LKDK+PDL+IYTDVALDPY DGHDGIV
Sbjct: 181 VVFPK-PDALKSPTGDEAYNENGLVPRTIRMLKDKFPDLIIYTDVALDPYYYDGHDGIVT 239
Query: 220 EDGVIMNDETVHQLCKQAVAQARAGADVVSPSDMMDGRVGAMRAALDAEGFQHVSIMSYT 279
+ GVIMNDETVHQLCKQAVAQARAGADVVSPSDMMDGRVGA+RAALDAEG+ +VSIMSYT
Sbjct: 240 QHGVIMNDETVHQLCKQAVAQARAGADVVSPSDMMDGRVGAIRAALDAEGYSNVSIMSYT 299
Query: 280 AKYASSFYGPFREALDSNPRFGDKKTYQMNPANYREALTEMREDETEGADILLVKPGLPY 339
AKYASSFYGPFREALDSNPRFGDKKTYQMNPANYREAL E +EDE+EGADILLVKPGLPY
Sbjct: 300 AKYASSFYGPFREALDSNPRFGDKKTYQMNPANYREALIETQEDESEGADILLVKPGLPY 359
Query: 340 LDIIRLLRDNSPLPIAAYQVSGEYSMIKAGGALKMIDEEKVMMESLLCLRRAGADIILTY 399
LDIIRLLRDNS LPIAAYQVSGEYSMIKAGG LKMIDEEKVM+ESLLCLRRAGADIILTY
Sbjct: 360 LDIIRLLRDNSDLPIAAYQVSGEYSMIKAGGVLKMIDEEKVMLESLLCLRRAGADIILTY 419
Query: 400 FALQAARCLCGEKR 413
FALQAARCLCGEKR
Sbjct: 420 FALQAARCLCGEKR 433
>HEM2_HORVU (Q42836) Delta-aminolevulinic acid dehydratase,
chloroplast precursor (EC 4.2.1.24) (Porphobilinogen
synthase) (ALADH)
Length = 428
Score = 585 bits (1507), Expect = e-167
Identities = 294/369 (79%), Positives = 320/369 (86%), Gaps = 4/369 (1%)
Query: 46 TVRA----SDADFEAAVVAGNVPDAPPVPPTPAAPAGTPVVTSLPIQRRPRRNRRSATHR 101
TVRA S + EA VAG P V TP AP GTP + L + +RPRRNRRS R
Sbjct: 55 TVRAPSGRSIEECEADAVAGRFPAPSCVCQTPKAPDGTPEIRPLDMAKRPRRNRRSPALR 114
Query: 102 SAFQETTLSPANFVYPLFIHEGEEDTPIGAMPGCYRLGWRHGLIEEVAKARDVGVNSVVL 161
+AFQET++SPAN V PLFIHEGEED PIGAMPGC+RLGW+HGL+ EV KARDVGVNS VL
Sbjct: 115 AAFQETSISPANLVLPLFIHEGEEDAPIGAMPGCFRLGWQHGLLAEVYKARDVGVNSFVL 174
Query: 162 FPKIPDALKTPTGDEAYNENGLVPRTIRLLKDKYPDLVIYTDVALDPYSSDGHDGIVRED 221
FPK+PDALK+PTG EAYN+NGLVPRTIRLLKDK+PD+++YTDVALDPYSSDGHDGIVR+D
Sbjct: 175 FPKVPDALKSPTGVEAYNDNGLVPRTIRLLKDKFPDIIVYTDVALDPYSSDGHDGIVRKD 234
Query: 222 GVIMNDETVHQLCKQAVAQARAGADVVSPSDMMDGRVGAMRAALDAEGFQHVSIMSYTAK 281
GVI+NDETV+QLCKQAV+QARAGADVVSPS+MMDGRVGA+R+ALDAEGF VSIMSYTAK
Sbjct: 235 GVILNDETVYQLCKQAVSQARAGADVVSPSNMMDGRVGAIRSALDAEGFNDVSIMSYTAK 294
Query: 282 YASSFYGPFREALDSNPRFGDKKTYQMNPANYREALTEMREDETEGADILLVKPGLPYLD 341
YASSFYGPFREALDSNPRFGDKKTYQMNPANYREAL E DE EGADILLVKPGLPYLD
Sbjct: 295 YASSFYGPFREALDSNPRFGDKKTYQMNPANYREALLETAADEAEGADILLVKPGLPYLD 354
Query: 342 IIRLLRDNSPLPIAAYQVSGEYSMIKAGGALKMIDEEKVMMESLLCLRRAGADIILTYFA 401
IIRL RDNS LPIAAYQVSGEYSMIKAGGAL MIDEEKVMMESL+CLRRAGAD+ILTYFA
Sbjct: 355 IIRLSRDNSALPIAAYQVSGEYSMIKAGGALNMIDEEKVMMESLMCLRRAGADVILTYFA 414
Query: 402 LQAARCLCG 410
Q LCG
Sbjct: 415 RQPPAVLCG 423
>HEM2_SELMA (P45623) Delta-aminolevulinic acid dehydratase,
chloroplast precursor (EC 4.2.1.24) (Porphobilinogen
synthase) (ALADH) (ALAD)
Length = 417
Score = 573 bits (1477), Expect = e-163
Identities = 283/358 (79%), Positives = 311/358 (86%)
Query: 55 EAAVVAGNVPDAPPVPPTPAAPAGTPVVTSLPIQRRPRRNRRSATHRSAFQETTLSPANF 114
EA VV+GN P AP P AP GTPVV L + RPRRNR+SA R AFQETTL+PANF
Sbjct: 60 EADVVSGNPPAAPAAPAKAKAPPGTPVVKPLRLTSRPRRNRKSAALRDAFQETTLTPANF 119
Query: 115 VYPLFIHEGEEDTPIGAMPGCYRLGWRHGLIEEVAKARDVGVNSVVLFPKIPDALKTPTG 174
+ PLFIHEGEED+PIGAMPGC RLGWRHGLI+EV KARDVGVNSVVLFPKIPDALK+ TG
Sbjct: 120 ILPLFIHEGEEDSPIGAMPGCSRLGWRHGLIDEVYKARDVGVNSVVLFPKIPDALKSSTG 179
Query: 175 DEAYNENGLVPRTIRLLKDKYPDLVIYTDVALDPYSSDGHDGIVREDGVIMNDETVHQLC 234
DEAYN +GLVPR IR LKDK+PDLVIYTDVALDPYSSDGHDGIVREDGVIMNDETVHQLC
Sbjct: 180 DEAYNPDGLVPRAIRTLKDKFPDLVIYTDVALDPYSSDGHDGIVREDGVIMNDETVHQLC 239
Query: 235 KQAVAQARAGADVVSPSDMMDGRVGAMRAALDAEGFQHVSIMSYTAKYASSFYGPFREAL 294
KQAVAQA AGADVVSPSDMMDGRVGA+R ALD G+ HVSIM+YTAKYAS+FY PFRE L
Sbjct: 240 KQAVAQAEAGADVVSPSDMMDGRVGAIRTALDEAGYYHVSIMAYTAKYASAFYEPFREEL 299
Query: 295 DSNPRFGDKKTYQMNPANYREALTEMREDETEGADILLVKPGLPYLDIIRLLRDNSPLPI 354
DSNPRFGDKKTYQMNP NYREAL E+ DE+EGADIL+VKP +PYL +IRLLRD S LPI
Sbjct: 300 DSNPRFGDKKTYQMNPENYREALLEVHADESEGADILMVKPAMPYLHVIRLLRDTSALPI 359
Query: 355 AAYQVSGEYSMIKAGGALKMIDEEKVMMESLLCLRRAGADIILTYFALQAARCLCGEK 412
+AYQVSGEYSMIKA + M+DE+K ++ESLLC++RAGAD+ILTY ALQAAR LCGEK
Sbjct: 360 SAYQVSGEYSMIKAAASQGMLDEKKAILESLLCIKRAGADVILTYAALQAARWLCGEK 417
>HEM2_PHYPA (Q43058) Delta-aminolevulinic acid dehydratase,
chloroplast precursor (EC 4.2.1.24) (Porphobilinogen
synthase) (ALADH)
Length = 430
Score = 562 bits (1449), Expect = e-160
Identities = 279/358 (77%), Positives = 314/358 (86%), Gaps = 2/358 (0%)
Query: 55 EAAVVAGNVPDAPPVPPTPAAPAGTPVVTSLPIQRRPRRNRRSATHRSAFQETTLSPANF 114
EA VVAGN P APPVP P+AP GTP ++ L + RPRRNRRS R+AFQETT+SPANF
Sbjct: 74 EANVVAGNAPAAPPVPAKPSAPEGTPAISPLVMPARPRRNRRSPALRAAFQETTISPANF 133
Query: 115 VYPLFIHEGEEDTPIGAMPGCYRLGWRHGLIEEVAKARDVGVNSVVLFPKIPDALKTPTG 174
+ PLF+HEGE++ PIGAMPGC RLGWRHGLI+EV KARDVGVNSVVLFPK+PDALK+ TG
Sbjct: 134 ILPLFVHEGEQNAPIGAMPGCQRLGWRHGLIDEVYKARDVGVNSVVLFPKVPDALKSSTG 193
Query: 175 DEAYNENGLVPRTIRLLKDKYPDLVIYTDVALDPYSSDGHDGIVREDGVIMNDETVHQLC 234
DEAYN +GLVPR IRLLK PDLVIYTDVALDPYSSDGHDGIVREDG+IMNDETVHQLC
Sbjct: 194 DEAYNPDGLVPRCIRLLK-AIPDLVIYTDVALDPYSSDGHDGIVREDGLIMNDETVHQLC 252
Query: 235 KQAVAQARAGADVVSPSDMMDGRVGAMRAALDAEGFQHVSIMSYTAKYASSFYGPFREAL 294
KQAVAQA+AGADVVSPSDMMDGRVGA+R ALD G Q VSI++YTAKYAS+FYGP REAL
Sbjct: 253 KQAVAQAQAGADVVSPSDMMDGRVGAIRKALDLAGHQDVSIIAYTAKYASAFYGPSREAL 312
Query: 295 DSNPRFGDKKTYQMNPANYREALTEMREDETEGADILLVKPGLPYLDIIRLLRDNSPLPI 354
DSNPRFGDKKTYQMNPANYREAL E R DE EGADIL+VKP +PYLD+IRLLRDN+ LPI
Sbjct: 313 DSNPRFGDKKTYQMNPANYREALIETRMDEAEGADILMVKPAMPYLDVIRLLRDNTALPI 372
Query: 355 AAYQVSGEYSMIKAGGALKMIDEEKVMMESLLCLRRAGADIILTYFALQAARCLCGEK 412
+AYQVSGEYSMI+A G M+DE+K ++ESLL +RRAGAD+ILTYFA+QAA+ LC E+
Sbjct: 373 SAYQVSGEYSMIRA-GCRGMLDEKKAVLESLLSIRRAGADVILTYFAIQAAQWLCAER 429
>HEM2_CHLRE (Q42682) Delta-aminolevulinic acid dehydratase,
chloroplast precursor (EC 4.2.1.24) (Porphobilinogen
synthase) (ALADH)
Length = 390
Score = 434 bits (1117), Expect = e-121
Identities = 210/346 (60%), Positives = 270/346 (77%), Gaps = 9/346 (2%)
Query: 76 PAGTPVVTSLPIQRRPRRNRRSATHRSAFQETTLSPANFVYPLFIHE-GEEDTPIGAMPG 134
P GTP+VT + RPRRNRRS + R++ +E +SPANF+ P+FIHE ++ PI +MPG
Sbjct: 45 PEGTPIVTPQDLPSRPRRNRRSESFRASVREVNVSPANFILPIFIHEESNQNVPIASMPG 104
Query: 135 CYRLGWRHGLIEEVAKARDVGVNSVVLFPKIPDALKTPTGDEAYNENGLVPRTIRLLKDK 194
RL + +I+ VA+ R GVN VV+FPK PD LKT T +EA+N+NGL RTIRLLKD
Sbjct: 105 INRLAYGKNVIDYVAEPRSYGVNQVVVFPKTPDHLKTQTAEEAFNKNGLSQRTIRLLKDS 164
Query: 195 YPDLVIYTDVALDPYSSDGHDGIVREDGVIMNDETVHQLCKQAVAQARAGADVVSPSDMM 254
+PDL +YTDVALDPY+SDGHDGIV + GVI+NDET+ LC+QAV+QA AGADVVSPSDMM
Sbjct: 165 FPDLEVYTDVALDPYNSDGHDGIVSDAGVILNDETIEYLCRQAVSQAEAGADVVSPSDMM 224
Query: 255 DGRVGAMRAALDAEGFQHVSIMSYTAKYASSFYGPFREALDSNPRFG--------DKKTY 306
DGRVGA+R ALD EGF +VSIMSYTAKYAS++YGPFR+AL S P+ G +KKTY
Sbjct: 225 DGRVGAIRRALDREGFTNVSIMSYTAKYASAYYGPFRDALASAPKPGQAHRRIPPNKKTY 284
Query: 307 QMNPANYREALTEMREDETEGADILLVKPGLPYLDIIRLLRDNSPLPIAAYQVSGEYSMI 366
QM+PANYREA+ E + DE EGADI++VKPG+PYLD++RLLR+ SPLP+A Y VSGEY+M+
Sbjct: 285 QMDPANYREAIREAKADEAEGADIMMVKPGMPYLDVVRLLRETSPLPVAVYHVSGEYAML 344
Query: 367 KAGGALKMIDEEKVMMESLLCLRRAGADIILTYFALQAARCLCGEK 412
KA ++E+ ++E++ C RRAG D+ILTY+ ++A++ L GEK
Sbjct: 345 KAAAERGWLNEKDAVLEAMTCFRRAGGDLILTYYGIEASKWLAGEK 390
>HEM2_CHLTE (Q8KCJ0) Delta-aminolevulinic acid dehydratase (EC
4.2.1.24) (Porphobilinogen synthase) (ALAD) (ALADH)
Length = 328
Score = 333 bits (853), Expect = 6e-91
Identities = 181/327 (55%), Positives = 231/327 (70%), Gaps = 9/327 (2%)
Query: 85 LPIQRRPRRNRRSATHRSAFQETTLSPANFVYPLFIHEGE---EDTPIGAMPGCYRLGWR 141
L I RPRR RR+A R+ QE TL+ + V+PLF+ G E+ P +MPG +R
Sbjct: 7 LNIVHRPRRLRRTAALRNLVQENTLTVNDLVFPLFVMPGTNAVEEVP--SMPGSFRFTID 64
Query: 142 HGLIEEVAKARDVGVNSVVLFPKIPDALKTPTGDEAYNENGLVPRTIRLLKDKYPDLVIY 201
+EE + D+G+ ++ LF IP+ KT G EAYN+NG++ + IR +K P+L I
Sbjct: 65 RA-VEECKELYDLGIQAIDLFG-IPEK-KTEDGSEAYNDNGILQQAIRAIKKAVPELCIM 121
Query: 202 TDVALDPYSSDGHDGIVREDGVIMNDETVHQLCKQAVAQARAGADVVSPSDMMDGRVGAM 261
TDVALDP++ GHDG+VR DG+I+NDETV L K AV+ A AGAD VSPSDMMDGR+GA+
Sbjct: 122 TDVALDPFTPFGHDGLVR-DGIILNDETVEVLQKMAVSHAEAGADFVSPSDMMDGRIGAI 180
Query: 262 RAALDAEGFQHVSIMSYTAKYASSFYGPFREALDSNPRFGDKKTYQMNPANYREALTEMR 321
R ALD V I+SY AKYASSFYGPFR+AL S P+FGDK TYQMNPAN EA+ E+
Sbjct: 181 REALDESDHSDVGILSYAAKYASSFYGPFRDALHSAPQFGDKSTYQMNPANTDEAMKEVE 240
Query: 322 EDETEGADILLVKPGLPYLDIIRLLRDNSPLPIAAYQVSGEYSMIKAGGALKMIDEEKVM 381
D EGADI++VKPGL YLDI+ ++ +P+A Y VSGEY+M+KA A IDEE+VM
Sbjct: 241 LDIIEGADIVMVKPGLAYLDIVWRTKERFDVPVAIYHVSGEYAMVKAAAANGWIDEERVM 300
Query: 382 MESLLCLRRAGADIILTYFALQAARCL 408
MESLLC++RAGADII TY+A +AA+ L
Sbjct: 301 MESLLCMKRAGADIIFTYYAKEAAKKL 327
>HEM2_CHLVI (Q59334) Delta-aminolevulinic acid dehydratase (EC
4.2.1.24) (Porphobilinogen synthase) (ALAD) (ALADH)
Length = 328
Score = 332 bits (850), Expect = 1e-90
Identities = 177/325 (54%), Positives = 228/325 (69%), Gaps = 5/325 (1%)
Query: 85 LPIQRRPRRNRRSATHRSAFQETTLSPANFVYPLFIHEGEEDTP-IGAMPGCYRLGWRHG 143
L I RPRR RR+A R+ QE TL+ + V+PLF+ G + +MPG +R
Sbjct: 7 LNIVHRPRRLRRTAALRNLVQENTLTVNDLVFPLFVMPGTNAVEEVSSMPGSFRFTIDRA 66
Query: 144 LIEEVAKARDVGVNSVVLFPKIPDALKTPTGDEAYNENGLVPRTIRLLKDKYPDLVIYTD 203
+EE + D+G+ + LF IP+ KT G EAYN+NG++ + IR +K P+L I TD
Sbjct: 67 -VEECKELYDLGIQGIDLFG-IPEQ-KTEDGSEAYNDNGILQQAIRAIKKAVPELCIMTD 123
Query: 204 VALDPYSSDGHDGIVREDGVIMNDETVHQLCKQAVAQARAGADVVSPSDMMDGRVGAMRA 263
VALDP++ GHDG+V+ DG+I+NDETV L K AV+ A AGAD VSPSDMMDGR+GA+R
Sbjct: 124 VALDPFTPFGHDGLVK-DGIILNDETVEVLQKMAVSHAEAGADFVSPSDMMDGRIGAIRE 182
Query: 264 ALDAEGFQHVSIMSYTAKYASSFYGPFREALDSNPRFGDKKTYQMNPANYREALTEMRED 323
ALD V I+SY AKYASSFYGPFR+AL S P+FGDK TYQMNPAN EA+ E+ D
Sbjct: 183 ALDETDHSDVGILSYAAKYASSFYGPFRDALHSAPQFGDKSTYQMNPANTEEAMKEVELD 242
Query: 324 ETEGADILLVKPGLPYLDIIRLLRDNSPLPIAAYQVSGEYSMIKAGGALKMIDEEKVMME 383
EGADI++VKPGL YLDI+ ++ +P+A Y VSGEY+M+KA A IDE++VMME
Sbjct: 243 IVEGADIVMVKPGLAYLDIVWRTKERFDVPVAIYHVSGEYAMVKAAAAKGWIDEDRVMME 302
Query: 384 SLLCLRRAGADIILTYFALQAARCL 408
SLLC++RAGADII TY+A +AA+ L
Sbjct: 303 SLLCMKRAGADIIFTYYAKEAAKKL 327
>HEM2_BACHD (Q9K8G2) Delta-aminolevulinic acid dehydratase (EC
4.2.1.24) (Porphobilinogen synthase) (ALAD) (ALADH)
Length = 328
Score = 295 bits (754), Expect = 2e-79
Identities = 159/327 (48%), Positives = 222/327 (67%), Gaps = 9/327 (2%)
Query: 89 RRPRRNRRSATHRSAFQETTLSPANFVYPLFIHEGE---EDTPIGAMPGCYRLGWRHGLI 145
+R RR R++A R+ +ET L + +YP+F+ EGE ++ P +MP Y+L L
Sbjct: 8 KRHRRLRQTAAIRNMVRETKLHIDDLIYPIFVKEGEGVRQEVP--SMPNVYQLSLDQ-LD 64
Query: 146 EEVAKARDVGVNSVVLFPKIPDALKTPTGDEAYNENGLVPRTIRLLKDKYPDLVIYTDVA 205
EV + +G+ +++LF +P A K G AY+E+G+V + IR +K+ YPDL + D
Sbjct: 65 AEVDEIVSLGIPAIILFG-VP-AEKDAVGSAAYHEHGIVQQAIRQVKESYPDLTVIADTC 122
Query: 206 LDPYSSDGHDGIVREDGVIMNDETVHQLCKQAVAQARAGADVVSPSDMMDGRVGAMRAAL 265
L ++ GH G++ E+G I+ND ++ L + AV+QA+AGAD+++PS+MMDG V A+RA L
Sbjct: 123 LCQFTDHGHCGVI-EEGKILNDPSLDLLARTAVSQAKAGADIIAPSNMMDGFVAAIRAGL 181
Query: 266 DAEGFQHVSIMSYTAKYASSFYGPFREALDSNPRFGDKKTYQMNPANYREALTEMREDET 325
D+ GF V +MSY KYAS+FYGPFR+A S+P FGD+KTYQM+PAN EAL E R D
Sbjct: 182 DSAGFTDVPVMSYAVKYASAFYGPFRDAAHSSPVFGDRKTYQMDPANRLEALREARSDVE 241
Query: 326 EGADILLVKPGLPYLDIIRLLRDNSPLPIAAYQVSGEYSMIKAGGALKMIDEEKVMMESL 385
EGAD L+VKP L YLDIIR +++ + LP+ AY VSGEYSMIKA IDE+ ++E L
Sbjct: 242 EGADFLIVKPALSYLDIIREVKNETGLPVVAYNVSGEYSMIKAASLQGWIDEKSTVLEKL 301
Query: 386 LCLRRAGADIILTYFALQAARCLCGEK 412
+ ++RAGAD+ILTYFA AR L EK
Sbjct: 302 ISMKRAGADLILTYFAKDVARWLNEEK 328
>HEM2_AQUAE (O67876) Delta-aminolevulinic acid dehydratase (EC
4.2.1.24) (Porphobilinogen synthase) (ALAD) (ALADH)
Length = 330
Score = 294 bits (753), Expect = 2e-79
Identities = 155/322 (48%), Positives = 222/322 (68%), Gaps = 9/322 (2%)
Query: 90 RPRRNRRSATHRSAFQETTLSPANFVYPLFIHEGE---EDTPIGAMPGCYRLGWRHGLIE 146
RPRR RR+ R +ET L+ + +YP+F+ GE E+ P +MPG YR +++
Sbjct: 10 RPRRLRRNENIRRLVRETHLTLDDLIYPIFVRWGENVVEEVP--SMPGVYRYSVDK-VVD 66
Query: 147 EVAKARDVGVNSVVLFPKIPDALKTPTGDEAYNENGLVPRTIRLLKDKYPDLVIYTDVAL 206
V + RD+G+ +++LF IP+ K G + ++E G++ R +R +K + PD+ + TDV
Sbjct: 67 AVKEVRDLGIPAIILFG-IPEH-KDEVGSDTWSEEGIIQRALRKIKKEVPDIYVITDVCF 124
Query: 207 DPYSSDGHDGIVREDGVIMNDETVHQLCKQAVAQARAGADVVSPSDMMDGRVGAMRAALD 266
Y++ GH G++ + V ND T+ L KQ V+ A GAD+V+PS MMDG V +R ALD
Sbjct: 125 CEYTTHGHCGVLHDHDV-ENDLTLENLKKQVVSHAENGADMVAPSGMMDGMVKVIREALD 183
Query: 267 AEGFQHVSIMSYTAKYASSFYGPFREALDSNPRFGDKKTYQMNPANYREALTEMREDETE 326
GF+H+ IM+Y+AK+AS++YGPFREA +S P FGD++TYQM+PAN REAL E+ D E
Sbjct: 184 EAGFKHIPIMAYSAKFASAYYGPFREAAESAPAFGDRRTYQMDPANSREALKEVLMDVEE 243
Query: 327 GADILLVKPGLPYLDIIRLLRDNSPLPIAAYQVSGEYSMIKAGGALKMIDEEKVMMESLL 386
GAD+++VKP L YLDII +++N +P+ AY VSGEYS+IKA G L IDE+KVM E+LL
Sbjct: 244 GADVVMVKPALAYLDIIAKVKENVLVPVCAYNVSGEYSLIKAAGKLGWIDEKKVMWETLL 303
Query: 387 CLRRAGADIILTYFALQAARCL 408
++RAGAD+I+TYFA AAR +
Sbjct: 304 SIKRAGADMIITYFAKDAARMI 325
>HEM2_BRAJA (P45622) Delta-aminolevulinic acid dehydratase (EC
4.2.1.24) (Porphobilinogen synthase) (ALAD) (ALADH)
Length = 353
Score = 291 bits (746), Expect = 2e-78
Identities = 154/333 (46%), Positives = 217/333 (64%), Gaps = 4/333 (1%)
Query: 78 GTPVVTSLPIQRRPRRNRRSATHRSAFQETTLSPANFVYPLFIHEGEEDTP-IGAMPGCY 136
G +L + RPRRNR++ R +E L+ + ++PLF+ +G I +MPG
Sbjct: 19 GAAASPALDLAIRPRRNRKAEWARRMVRENVLTTDDLIWPLFLIDGNNKREQIASMPGVE 78
Query: 137 RLGWRHGLIEEVAKARDVGVNSVVLFPKIPDALKTPTGDEAYNENGLVPRTIRLLKDKYP 196
RL + E +A + + + LFP +L+ G EA N N LV + +R +K ++P
Sbjct: 79 RLSVDQA-VREAERAMKLTIPCIALFPYTDPSLRDEEGSEACNPNNLVCQAVRAIKKEFP 137
Query: 197 DLVIYTDVALDPYSSDGHDGIVREDGVIMNDETVHQLCKQAVAQARAGADVVSPSDMMDG 256
++ + DVALDP++S GHDG++ DG I+NDETV L +QA+ QA AG D+++PSDMMDG
Sbjct: 138 EIGVLCDVALDPFTSHGHDGLIA-DGAILNDETVAVLVRQALVQAEAGCDIIAPSDMMDG 196
Query: 257 RVGAMRAALDAEGFQHVSIMSYTAKYASSFYGPFREALDSNPRF-GDKKTYQMNPANYRE 315
RV A+R LD G V IM+Y AKYAS+FYGPFR+A+ S GDK+TYQM+ AN E
Sbjct: 197 RVAAIREGLDQAGLIDVQIMAYAAKYASAFYGPFRDAIGSAKTLTGDKRTYQMDSANTDE 256
Query: 316 ALTEMREDETEGADILLVKPGLPYLDIIRLLRDNSPLPIAAYQVSGEYSMIKAGGALKMI 375
AL E+ D +EGAD+++VKPG+PYLD++R ++D +P AYQVSGEY+MI A +
Sbjct: 257 ALREVELDISEGADMVMVKPGMPYLDVVRRVKDTFAMPTFAYQVSGEYAMIAAAAGNGWL 316
Query: 376 DEEKVMMESLLCLRRAGADIILTYFALQAARCL 408
D ++ MMESLL +RAGAD +L+YFA +AA L
Sbjct: 317 DGDRAMMESLLAFKRAGADGVLSYFAPKAAEKL 349
>HEM2_RHOCA (P42504) Delta-aminolevulinic acid dehydratase (EC
4.2.1.24) (Porphobilinogen synthase) (ALAD) (ALADH)
Length = 332
Score = 288 bits (737), Expect = 2e-77
Identities = 153/321 (47%), Positives = 214/321 (66%), Gaps = 4/321 (1%)
Query: 90 RPRRNRRSATHRSAFQETTLSPANFVYPLFIHEGE-EDTPIGAMPGCYRLGWRHGLIEEV 148
R RR RR+ R QE LS + ++P+FI + D I +MPG R G ++
Sbjct: 12 RLRRMRRTEALRDLAQENRLSVKDLIWPIFITDVPGADVEISSMPGVVRRTM-DGALKAA 70
Query: 149 AKARDVGVNSVVLFPKIPDALKTPTGDEAYNENGLVPRTIRLLKDKYPDLVIYTDVALDP 208
+RD G + + P A+KT T + A+ + R I +K P++ I TD+ALDP
Sbjct: 71 EGSRDAGHSRDLPVPLTDPAVKTETCEMAWQPDNFTNRVIAAMKQAVPEVAIMTDIALDP 130
Query: 209 YSSDGHDGIVREDGVIMNDETVHQLCKQAVAQARAGADVVSPSDMMDGRVGAMRAALDAE 268
Y+++GHDG+VR DG+++NDET L K A+AQA AGAD++ PSDMMDGRVGA+R A++A
Sbjct: 131 YNANGHDGLVR-DGILLNDETTEALVKMALAQAAAGADILGPSDMMDGRVGAIRQAMEAA 189
Query: 269 GFQHVSIMSYTAKYASSFYGPFREALDSNPRF-GDKKTYQMNPANYREALTEMREDETEG 327
G + ++I+SY AKYAS+FYGPFR+A+ ++ GDKKTYQMNPAN EAL + D EG
Sbjct: 190 GHKDIAILSYAAKYASAFYGPFRDAVGASSALKGDKKTYQMNPANSAEALRNVARDIAEG 249
Query: 328 ADILLVKPGLPYLDIIRLLRDNSPLPIAAYQVSGEYSMIKAGGALKMIDEEKVMMESLLC 387
AD+++VKPG+PYLDI+R ++D +P AYQVSGEY+M+ A ++ +KVM+ESL+
Sbjct: 250 ADMVMVKPGMPYLDIVRQVKDAFGMPTYAYQVSGEYAMLMAAVQNGWLNHDKVMLESLMA 309
Query: 388 LRRAGADIILTYFALQAARCL 408
RRAG D +LTYFA AA+ +
Sbjct: 310 FRRAGCDGVLTYFAPAAAKLI 330
>HEM2_BACSU (P30950) Delta-aminolevulinic acid dehydratase (EC
4.2.1.24) (Porphobilinogen synthase) (ALAD) (ALADH)
Length = 324
Score = 286 bits (731), Expect = 9e-77
Identities = 150/320 (46%), Positives = 220/320 (67%), Gaps = 5/320 (1%)
Query: 90 RPRRNRRSATHRSAFQETTLSPANFVYPLFIHEG-EEDTPIGAMPGCYRLGWRHGLIEEV 148
R RR R S R +ET L P++F+YP+F+ EG E + +MP + + L +EV
Sbjct: 7 RHRRLRTSKAMREMVKETRLHPSDFIYPIFVVEGLEGKKAVPSMPDVHHVSLDL-LKDEV 65
Query: 149 AKARDVGVNSVVLFPKIPDALKTPTGDEAYNENGLVPRTIRLLKDKYPDLVIYTDVALDP 208
A+ +G+ SV++F IP+ K G +AY+++G+V + I +K+ +P++V+ D L
Sbjct: 66 AELVKLGIQSVIVFG-IPEE-KDDCGTQAYHDHGIVQKAITEIKEHFPEMVVVADTCLCE 123
Query: 209 YSSDGHDGIVREDGVIMNDETVHQLCKQAVAQARAGADVVSPSDMMDGRVGAMRAALDAE 268
Y+ GH G+V+ DGVI+NDE++ L + AV+QA+AGAD+++PS+MMDG V +R ALD E
Sbjct: 124 YTDHGHCGLVK-DGVILNDESLELLAQTAVSQAKAGADIIAPSNMMDGFVTVIREALDKE 182
Query: 269 GFQHVSIMSYTAKYASSFYGPFREALDSNPRFGDKKTYQMNPANYREALTEMREDETEGA 328
GF ++ IMSY KY+S FYGPFR+A +S P+FGD+KTYQM+PAN EAL E + D EGA
Sbjct: 183 GFVNIPIMSYAVKYSSEFYGPFRDAANSTPQFGDRKTYQMDPANRMEALREAQSDVEEGA 242
Query: 329 DILLVKPGLPYLDIIRLLRDNSPLPIAAYQVSGEYSMIKAGGALKMIDEEKVMMESLLCL 388
D L+VKP L Y+DI+R +++ LP+ AY VSGEYSM+KA I E+++++E L +
Sbjct: 243 DFLIVKPSLSYMDIMRDVKNEFTLPLVAYNVSGEYSMVKAAAQNGWIKEKEIVLEILTSM 302
Query: 389 RRAGADIILTYFALQAARCL 408
+RAGAD+I+TY A AA+ L
Sbjct: 303 KRAGADLIITYHAKDAAKWL 322
>HEM2_SYNP7 (P43087) Delta-aminolevulinic acid dehydratase (EC
4.2.1.24) (Porphobilinogen synthase) (ALAD) (ALADH)
Length = 326
Score = 284 bits (726), Expect = 3e-76
Identities = 153/323 (47%), Positives = 214/323 (65%), Gaps = 7/323 (2%)
Query: 90 RPRRNRRSATHRSAFQETTLSPANFVYPLFIHEGEEDTP-IGAMPGCYRLGWRHGLIEEV 148
RPRR R S T R +ETTL+ A+F+YPLF GE + +MPG Y+L ++EE
Sbjct: 6 RPRRLRSSETLRRMVRETTLTSADFIYPLFAVPGEGVAKEVTSMPGVYQLSIDK-IVEEA 64
Query: 149 AKARDVGVNSVVLFPKIPDALKTPTGDEAYNENGLVPRTIRLLKDKYPDLVIYTDVALDP 208
+ D+G+ S++LF D TG A+++ G+V + +K+ P+L++ D L
Sbjct: 65 KEVYDLGIPSIILFGIPTDKDNDATG--AWHDCGIVQKAATAVKEAVPELIVAADTCLCE 122
Query: 209 YSSDGHDGIVRE---DGVIMNDETVHQLCKQAVAQARAGADVVSPSDMMDGRVGAMRAAL 265
Y+ GH G + G ++ND T+ L K AV+QA+AGAD+++PS MMDG V +R AL
Sbjct: 123 YTPHGHCGYLEVGDLSGRVLNDPTLELLRKTAVSQAKAGADIIAPSGMMDGFVATIRDAL 182
Query: 266 DAEGFQHVSIMSYTAKYASSFYGPFREALDSNPRFGDKKTYQMNPANYREALTEMREDET 325
D GF IM+Y+AKYAS++YGPFR+A +S P+FGD++TYQM+P N REAL E+ D
Sbjct: 183 DEAGFSDTPIMAYSAKYASAYYGPFRDAAESTPQFGDRRTYQMDPGNSREALKEVELDVA 242
Query: 326 EGADILLVKPGLPYLDIIRLLRDNSPLPIAAYQVSGEYSMIKAGGALKMIDEEKVMMESL 385
EGADI++VKP L Y+DII +++ + LP+AAY VSGEYSM+KA IDEE+V++E+L
Sbjct: 243 EGADIVMVKPALSYMDIICRIKETTDLPVAAYNVSGEYSMVKAARLNGWIDEERVVLETL 302
Query: 386 LCLRRAGADIILTYFALQAARCL 408
+RAGAD+ILTY A AAR L
Sbjct: 303 TSFKRAGADLILTYHAKDAARWL 325
>HEM2_METJA (Q60178) Delta-aminolevulinic acid dehydratase (EC
4.2.1.24) (Porphobilinogen synthase) (ALAD) (ALADH)
Length = 335
Score = 283 bits (725), Expect = 4e-76
Identities = 158/322 (49%), Positives = 216/322 (67%), Gaps = 12/322 (3%)
Query: 90 RPRRNRRSATHRSAFQETTLSPANFVYPLFIHE---GEEDTPIGAMPGCYRLGWRHGLIE 146
RPRR R++ R +ET L+ + + P+F+ E G E I +MP YR G IE
Sbjct: 13 RPRRLRKNQKIRDLVRETILTKNDLIMPIFVDENLKGNEKKEISSMPNQYRFSVE-GAIE 71
Query: 147 EVAKARDVGVNSVVLF--PKIPDALKTPTGDEAYNENGLVPRTIRLLKDKYPD-LVIYTD 203
E + D+G+ +V+LF PK D + + AY++NG+V RTIR +K++ D L++ D
Sbjct: 72 EAKEIADLGIPAVILFGIPKHKDEIAS----SAYDKNGVVQRTIRGIKEELGDELLVIAD 127
Query: 204 VALDPYSSDGHDGIVREDGVIMNDETVHQLCKQAVAQARAGADVVSPSDMMDGRVGAMRA 263
L Y+S GH GIV+ DG I+ND T+ L K A++ A AG D+V+PSDMMDGRV A+R
Sbjct: 128 CCLCEYTSHGHCGIVK-DGKILNDATLPILAKIALSYADAGVDIVAPSDMMDGRVRAIRE 186
Query: 264 ALDAEGFQHVSIMSYTAKYASSFYGPFREALDSNPRFGDKKTYQMNPANYREALTEMRED 323
L+ G+ V+IMSY+AKYASSFYGPFREA +S P+FGD+K+YQM+ N REAL E+ D
Sbjct: 187 ILEENGYDDVAIMSYSAKYASSFYGPFREAAESAPKFGDRKSYQMDIGNAREALKEIALD 246
Query: 324 ETEGADILLVKPGLPYLDIIRLLRDNSPLPIAAYQVSGEYSMIKAGGALKMIDEEKVMME 383
EGAD++LVKP LPYLDIIR+ +D +PI Y VSGEY+M++A +D EKV+ E
Sbjct: 247 IEEGADLILVKPALPYLDIIRMAKDRFDVPIGGYCVSGEYAMVEAAARNGWLDREKVIYE 306
Query: 384 SLLCLRRAGADIILTYFALQAA 405
LL ++RAGAD I+TY+A + A
Sbjct: 307 ILLSIKRAGADFIITYWAKEVA 328
>HEM2_METSC (Q02250) Delta-aminolevulinic acid dehydratase (EC
4.2.1.24) (Porphobilinogen synthase) (ALAD) (ALADH)
Length = 320
Score = 282 bits (721), Expect = 1e-75
Identities = 160/313 (51%), Positives = 216/313 (68%), Gaps = 7/313 (2%)
Query: 90 RPRRNRRSATHRSAFQETTLSPANFVYPLFIHEG-EEDTPIGAMPGCYRLGWRHGLIEEV 148
R RR R+++ RS +ETTLS + +YP+F+ EG + I MPG YR LI+E
Sbjct: 7 RMRRLRKNSKIRSLVKETTLSKDDLIYPVFVKEGIKTKEKIPKMPGQYRYSVDE-LIDEA 65
Query: 149 AKARDVGVNSVVLFPKIPDALKTPTGDEAYNENGLVPRTIRLLKDKYPDLVIYTDVALDP 208
K + G+ ++++F IP K G AY+ NG+V ++++LLK++ DLV+ TDV L
Sbjct: 66 KKLEEKGLKAILVFG-IPKK-KDKYGSSAYDPNGIVQKSVKLLKEE-TDLVVITDVCLCQ 122
Query: 209 YSSDGHDGIVREDGVIMNDETVHQLCKQAVAQARAGADVVSPSDMMDGRVGAMRAALDAE 268
Y+ GH GIV+ ++ NDET+ L K A++ A AGADVV+PSDMMDGRV A+R L+
Sbjct: 123 YTEHGHCGIVKNKKIV-NDETLKYLSKVALSHAEAGADVVAPSDMMDGRVKAIREELEKN 181
Query: 269 GFQHVSIMSYTAKYASSFYGPFREALDSNPRFGDKKTYQMNPANYREALTEMREDETEGA 328
GF V IMSY+AKYASSFY PFR A+ S+P FGD+ TYQM+P N EAL E++ D EGA
Sbjct: 182 GFDDVIIMSYSAKYASSFYEPFRSAVYSSPAFGDRSTYQMDPPNSLEALREVKLDIDEGA 241
Query: 329 DILLVKPGLPYLDIIRLLRDNSPLPIAAYQVSGEYSMIKAGGALKMIDEEKVMMESLLCL 388
DI++VKP LPYLDIIRL++D +P AAY VSGEYSMIKA + KV++E+LL +
Sbjct: 242 DIVMVKPALPYLDIIRLVKDTFGVPTAAYNVSGEYSMIKAAIDANYL-SNKVIIETLLSI 300
Query: 389 RRAGADIILTYFA 401
+RAGAD+I+T+FA
Sbjct: 301 KRAGADLIITHFA 313
>HEM2_ECOLI (P15002) Delta-aminolevulinic acid dehydratase (EC
4.2.1.24) (Porphobilinogen synthase) (ALAD) (ALADH)
Length = 323
Score = 280 bits (716), Expect = 5e-75
Identities = 157/318 (49%), Positives = 210/318 (65%), Gaps = 6/318 (1%)
Query: 89 RRPRRNRRSATHRSAFQETTLSPANFVYPLFIHEGEED-TPIGAMPGCYRLGWRHGLIEE 147
+RPRR R+S R+ F+ETTLS + V P+F+ E +D + AMPG R+ +H L E
Sbjct: 5 QRPRRLRKSPALRAMFEETTLSLNDLVLPIFVEEEIDDYKAVEAMPGVMRIPEKH-LARE 63
Query: 148 VAKARDVGVNSVVLFPKIPDALKTPTGDEAYNENGLVPRTIRLLKDKYPDLVIYTDVALD 207
+ + + G+ SV+ F TG +A+ E+GLV R R+ K P++++ +D
Sbjct: 64 IERIANAGIRSVMTFGISHHT--DETGSDAWREDGLVARMSRICKQTVPEMIVMSDTCFC 121
Query: 208 PYSSDGHDGIVREDGVIMNDETVHQLCKQAVAQARAGADVVSPSDMMDGRVGAMRAALDA 267
Y+S GH G++ E GV ND T+ L KQAV A AGAD ++PS MDG+V A+R ALDA
Sbjct: 122 EYTSHGHCGVLCEHGVD-NDATLENLGKQAVVAAAAGADFIAPSAAMDGQVQAIRQALDA 180
Query: 268 EGFQHVSIMSYTAKYASSFYGPFREALDSNPRFGDKKTYQMNPANYREALTEMREDETEG 327
GF+ +IMSY+ K+ASSFYGPFREA S + GD+K+YQMNP N REA+ E DE +G
Sbjct: 181 AGFKDTAIMSYSTKFASSFYGPFREAAGSALK-GDRKSYQMNPMNRREAIRESLLDEAQG 239
Query: 328 ADILLVKPGLPYLDIIRLLRDNSPLPIAAYQVSGEYSMIKAGGALKMIDEEKVMMESLLC 387
AD L+VKP YLDI+R LR+ + LPI AYQVSGEY+MIK IDEEKV++ESL
Sbjct: 240 ADCLMVKPAGAYLDIVRELRERTELPIGAYQVSGEYAMIKFAALAGAIDEEKVVLESLGS 299
Query: 388 LRRAGADIILTYFALQAA 405
++RAGAD+I +YFAL A
Sbjct: 300 IKRAGADLIFSYFALDLA 317
>HEM2_CHLPN (Q9Z7G1) Delta-aminolevulinic acid dehydratase (EC
4.2.1.24) (Porphobilinogen synthase) (ALAD) (ALADH)
Length = 332
Score = 280 bits (715), Expect = 6e-75
Identities = 150/322 (46%), Positives = 209/322 (64%), Gaps = 5/322 (1%)
Query: 82 VTSLPIQRRPRRNRRSATHRSAFQETTLSPANFVYPLFIHEGEE-DTPIGAMPGCYRLGW 140
++SL + RRPRRNR++A R ET LSP + + P F+ G I ++PG +R W
Sbjct: 1 MSSLTLSRRPRRNRKTAAIRDLLAETHLSPKDLIAPFFVKYGNNIKEEIPSLPGVFR--W 58
Query: 141 RHGLI-EEVAKARDVGVNSVVLFPKIPDALKTPTGDEAYNENGLVPRTIRLLKDKYPDLV 199
L+ +E+ + G+ +V+LFP IPD LK G + N ++ +I +K+ +P L
Sbjct: 59 SLDLLLKEIERLCTYGLRAVMLFPIIPDDLKDAYGSYSSNPKNILCHSIHEIKNAFPHLC 118
Query: 200 IYTDVALDPYSSDGHDGIVREDGVIMNDETVHQLCKQAVAQARAGADVVSPSDMMDGRVG 259
+ +D+ALDPY++ GHDGI +G ++NDE+V A A GAD+V+PSDMMDGR+G
Sbjct: 119 LISDIALDPYTTHGHDGIFL-NGEVLNDESVRIFGNIATLHAEMGADIVAPSDMMDGRIG 177
Query: 260 AMRAALDAEGFQHVSIMSYTAKYASSFYGPFREALDSNPRFGDKKTYQMNPANYREALTE 319
+R+ LD G+ SIMSY+ KYAS Y PFR+AL S+ GDKK YQMNP N EAL E
Sbjct: 178 YIRSKLDQSGYSKTSIMSYSVKYASCLYSPFRDALSSHVTSGDKKQYQMNPKNVLEALLE 237
Query: 320 MREDETEGADILLVKPGLPYLDIIRLLRDNSPLPIAAYQVSGEYSMIKAGGALKMIDEEK 379
DE EGADIL+VKP YLD+I +R N+ LP+AAYQVSGEY+MI + +D+E
Sbjct: 238 SSLDEEEGADILMVKPAGLYLDVIYRIRQNTCLPLAAYQVSGEYAMILSAFQQGWLDKET 297
Query: 380 VMMESLLCLRRAGADIILTYFA 401
+ ESL+ ++RAGAD+I++Y A
Sbjct: 298 LFHESLIAIKRAGADMIISYSA 319
Database: sprot
Posted date: Nov 25, 2004 10:54 AM
Number of letters in database: 59,974,054
Number of sequences in database: 164,201
Lambda K H
0.318 0.135 0.397
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 51,209,308
Number of Sequences: 164201
Number of extensions: 2296481
Number of successful extensions: 10152
Number of sequences better than 10.0: 81
Number of HSP's better than 10.0 without gapping: 55
Number of HSP's successfully gapped in prelim test: 26
Number of HSP's that attempted gapping in prelim test: 9854
Number of HSP's gapped (non-prelim): 151
length of query: 413
length of database: 59,974,054
effective HSP length: 113
effective length of query: 300
effective length of database: 41,419,341
effective search space: 12425802300
effective search space used: 12425802300
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 67 (30.4 bits)
Medicago: description of AC140916.2