BLAST2 result
BLASTP 2.2.2 [Dec-14-2001]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= AC140916.14 - phase: 0 /pseudo
(541 letters)
Database: sprot
164,201 sequences; 59,974,054 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
NRM6_ARATH (Q9S9N8) Metal transporter Nramp6 (AtNramp6) 563 e-160
NRM1_ARATH (Q9SAH8) Metal transporter Nramp1 (AtNramp1) 558 e-158
NRM4_ARATH (Q9FN18) Metal transporter Nramp4 (AtNramp4) 298 2e-80
NRM2_ARATH (Q9C6B2) Metal transporter Nramp2 (AtNramp2) 298 3e-80
NRM5_ARATH (Q9SN36) Metal transporter Nramp5 (AtNramp5) 293 1e-78
NRM3_ARATH (Q9SNV9) Metal transporter Nramp3 (AtNramp3) 293 1e-78
NRM2_MOUSE (P49282) Natural resistance-associated macrophage pro... 288 3e-77
NRM2_HUMAN (P49281) Natural resistance-associated macrophage pro... 287 4e-77
NRM2_RAT (O54902) Natural resistance-associated macrophage prote... 284 4e-76
NRM1_PIG (O77741) Natural resistance-associated macrophage prote... 279 2e-74
NRM1_CEREL (P56436) Natural resistance-associated macrophage pro... 277 6e-74
MVL_DROME (P49283) Malvolio protein 276 7e-74
MNTH_ANASP (Q8ZSB0) Probable manganese transport protein mntH 275 2e-73
NRM1_HUMAN (P49279) Natural resistance-associated macrophage pro... 275 3e-73
MNTH_LISIN (Q92BT1) Probable manganese transport protein mntH 275 3e-73
NRM1_CANFA (Q9XT74) Natural resistance-associated macrophage pro... 274 5e-73
MNTH_LISMO (Q8Y773) Probable manganese transport protein mntH 274 5e-73
NRML_CAEEL (Q21434) NRAMP-like transporter smf-1 273 6e-73
NRM1_BUBBU (Q27946) Natural resistance-associated macrophage pro... 273 6e-73
NRM1_BOVIN (Q27981) Natural resistance-associated macrophage pro... 273 6e-73
>NRM6_ARATH (Q9S9N8) Metal transporter Nramp6 (AtNramp6)
Length = 527
Score = 563 bits (1450), Expect = e-160
Identities = 282/473 (59%), Positives = 362/473 (75%), Gaps = 14/473 (2%)
Query: 69 ETDLQAGANHGYELLWLVLIGLIFALIIQSLAANLGVTTGKHLSEVCEVEYPLFVKYCLW 128
ETDLQ+GA + YELLW++L+ AL+IQSLAANLGV TGKHL+E C EY + LW
Sbjct: 59 ETDLQSGAQYKYELLWIILVASCAALVIQSLAANLGVVTGKHLAEHCRAEYSKVPNFMLW 118
Query: 129 LLAEVAVIAADIPEVIGTAFALNILFNIPLWAGVLLTGFSTLLLLSLQRFGVRKLELLIT 188
++AE+AV+A DIPEVIGTAFALN+LFNIP+W GVLLTG STL+LL+LQ++G+RKLE LI
Sbjct: 119 VVAEIAVVACDIPEVIGTAFALNMLFNIPVWIGVLLTGLSTLILLALQQYGIRKLEFLIA 178
Query: 189 ILVFVMAGCFFAEMSYVNPPASGVLKGMFVPKLAGEGAVADAIALLGALIMPHNLFLHSA 248
LVF +A CFF E+ Y P VL G+FVP+L G GA AI+LLGA++MPHNLFLHSA
Sbjct: 179 FLVFTIALCFFVELHYSKPDPKEVLYGLFVPQLKGNGATGLAISLLGAMVMPHNLFLHSA 238
Query: 249 LVLSRKVPKSVRGINEACRYFLYESGFALFVAFLINVAMISVSGTVCSANDLSGDNVERC 308
LVLSRK+P+SV GI EACRY+L ESG AL VAFLINV++ISVSG VC+A+DLS ++ C
Sbjct: 239 LVLSRKIPRSVTGIKEACRYYLIESGLALMVAFLINVSVISVSGAVCNASDLSPEDRASC 298
Query: 309 NDLTLNSASFLLKNVLGRSSSTIYAIALLASGQSSTITGTYAGQYIMQGFLDIRMKRWKR 368
DL LN ASFLL+NV+G+ SS ++AIALLASGQSSTITGTYAGQY+MQGFLD+R++ W R
Sbjct: 299 QDLDLNKASFLLRNVVGKWSSKLFAIALLASGQSSTITGTYAGQYVMQGFLDLRLEPWLR 358
Query: 369 NLMTRCIAIAPSLAVAIIGGSSGSSRLIIIASMILSFELPFALIPLLKFSSSSTKMGPHK 428
N +TRC+AI PSL VA+IGGS+G+ +LIIIASMILSFELPFAL+PLLKF+SS TKMG H
Sbjct: 359 NFLTRCLAIIPSLIVALIGGSAGAGKLIIIASMILSFELPFALVPLLKFTSSKTKMGSHA 418
Query: 429 NSMIIITISWILGFGIISINVYYLSTAFVKWIIHSSLPKVANVFIGIIVFPLMAIYIASV 488
NS++I +++WI+G I+ IN+YYL ++F+K ++HS + VA VF+G++ F +A Y+A++
Sbjct: 419 NSLVISSVTWIIGGLIMGINIYYLVSSFIKLLLHSHMNLVAIVFLGVLGFSGIATYLAAI 478
Query: 489 IYLTFRKDTVEMFIETKNDTVMQNQVEKGIVDNGQLELSHVPYREDLADIPLP 541
YL RK+ + +D + RED+A++ LP
Sbjct: 479 SYLVLRKN--------------RESSSTHFLDFSNSQTEETLPREDIANMQLP 517
>NRM1_ARATH (Q9SAH8) Metal transporter Nramp1 (AtNramp1)
Length = 532
Score = 558 bits (1438), Expect = e-158
Identities = 281/470 (59%), Positives = 360/470 (75%), Gaps = 5/470 (1%)
Query: 69 ETDLQAGANHGYELLWLVLIGLIFALIIQSLAANLGVTTGKHLSEVCEVEYPLFVKYCLW 128
ETDLQAGA++ YELLW++L+ AL+IQSLAANLGV TGKHL+E C EY + LW
Sbjct: 67 ETDLQAGAHYKYELLWIILVASCAALVIQSLAANLGVVTGKHLAEQCRAEYSKVPNFMLW 126
Query: 129 LLAEVAVIAADIPEVIGTAFALNILFNIPLWAGVLLTGFSTLLLLSLQRFGVRKLELLIT 188
++AE+AV+A DIPEVIGTAFALN+LF+IP+W GVLLTG STL+LL+LQ++GVRKLE LI
Sbjct: 127 VVAEIAVVACDIPEVIGTAFALNMLFSIPVWIGVLLTGLSTLILLALQKYGVRKLEFLIA 186
Query: 189 ILVFVMAGCFFAEMSYVNPPASGVLKGMFVPKLAGEGAVADAIALLGALIMPHNLFLHSA 248
LVF +A CFF E+ Y P VL G+FVP+L G GA AI+LLGA++MPHNLFLHSA
Sbjct: 187 FLVFTIAICFFVELHYSKPDPGEVLHGLFVPQLKGNGATGLAISLLGAMVMPHNLFLHSA 246
Query: 249 LVLSRKVPKSVRGINEACRYFLYESGFALFVAFLINVAMISVSGTVCSANDLSGDNVERC 308
LVLSRK+P+S GI EACR++L ESG AL VAFLINV++ISVSG VC+A +LS ++ C
Sbjct: 247 LVLSRKIPRSASGIKEACRFYLIESGLALMVAFLINVSVISVSGAVCNAPNLSPEDRANC 306
Query: 309 NDLTLNSASFLLKNVLGRSSSTIYAIALLASGQSSTITGTYAGQYIMQGFLDIRMKRWKR 368
DL LN ASFLL+NV+G+ SS ++AIALLASGQSSTITGTYAGQY+MQGFLD+R++ W R
Sbjct: 307 EDLDLNKASFLLRNVVGKWSSKLFAIALLASGQSSTITGTYAGQYVMQGFLDLRLEPWLR 366
Query: 369 NLMTRCIAIAPSLAVAIIGGSSGSSRLIIIASMILSFELPFALIPLLKFSSSSTKMGPHK 428
NL+TRC+AI PSL VA+IGGS+G+ +LIIIASMILSFELPFAL+PLLKF+S TKMG H
Sbjct: 367 NLLTRCLAIIPSLIVALIGGSAGAGKLIIIASMILSFELPFALVPLLKFTSCKTKMGSHV 426
Query: 429 NSMIIITISWILGFGIISINVYYLSTAFVKWIIHSSLPKVANVFIGIIVFPLMAIYIASV 488
N M I ++W++G I+ IN+YYL ++F+K +IHS + + VF GI+ F +A+Y+A++
Sbjct: 427 NPMAITALTWVIGGLIMGINIYYLVSSFIKLLIHSHMKLILVVFCGILGFAGIALYLAAI 486
Query: 489 IYLTFRKDTVEMFIETKNDTVMQNQVEKGIVDNGQLELSHVPYREDLADI 538
YL FRK+ V + D+ + + + N QL P R +D+
Sbjct: 487 AYLVFRKNRVATSLLISRDSQNVETLPRQDIVNMQL-----PCRVSTSDV 531
>NRM4_ARATH (Q9FN18) Metal transporter Nramp4 (AtNramp4)
Length = 512
Score = 298 bits (763), Expect = 2e-80
Identities = 180/435 (41%), Positives = 262/435 (59%), Gaps = 24/435 (5%)
Query: 68 VETDLQAGANHGYELLWLVLIGLIFALIIQSLAANLGVTTGKHLSEVCEVEYPLFVKYCL 127
+E+DLQAGA GY L+WL++ L+IQ L+A LGV TG+HL+E+C EYP + + L
Sbjct: 72 LESDLQAGAIAGYSLIWLLMWATAIGLLIQLLSARLGVATGRHLAELCREEYPTWARMVL 131
Query: 128 WLLAEVAVIAADIPEVIGTAFALNILFN--IPLWAGVLLTGFSTLLLLSLQRFGVRKLEL 185
W++AE+A+I ADI EVIG+A A+ IL N +PLWAGV++T + L L+ +G+RKLE
Sbjct: 132 WIMAEIALIGADIQEVIGSAIAIKILSNGLVPLWAGVVITALDCFIFLFLENYGIRKLEA 191
Query: 186 LITILVFVMAGCFFAEMSYVNPPASGVLKGMFVPKLAGEGAVADAIALLGALIMPHNLFL 245
+ IL+ MA F P + +L G VPKL+ + A+ ++G +IMPHN+FL
Sbjct: 192 VFAILIATMALAFAWMFGQTKPSGTELLVGALVPKLSSR-TIKQAVGIVGCIIMPHNVFL 250
Query: 246 HSALVLSRKV-PKSVRGINEACRYFLYESGFALFVAFLINVAMISVSGTVCSANDLSGDN 304
HSALV SR+V PK + EA +Y+ ES AL V+F+INV + +V S
Sbjct: 251 HSALVQSREVDPKKRFRVKEALKYYSIESTGALAVSFIINVFVTTVFAK-------SFYG 303
Query: 305 VERCNDLTLNSASFLLKNVLGRSSST---IYAIALLASGQSSTITGTYAGQYIMQGFLDI 361
E + + L +A L++ G I+AI +LA+GQSSTITGTYAGQ+IM GFL++
Sbjct: 304 TEIADTIGLANAGQYLQDKYGGGFFPILYIWAIGVLAAGQSSTITGTYAGQFIMGGFLNL 363
Query: 362 RMKRWKRNLMTRCIAIAPSLAVAIIGGSSGS--SRLIIIASMILSFELPFALIPLLKFSS 419
+MK+W R L+TR AI P++ VA++ SS S L +++ S ++PFA+IPLL S
Sbjct: 364 KMKKWVRALITRSCAIIPTMIVALVFDSSDSMLDELNEWLNVLQSVQIPFAVIPLLCLVS 423
Query: 420 SSTKMGPHKNSMIIITISWILGFGIISINVYYLSTAFVKWIIHSSLPKVANVFIGIIVFP 479
+ MG K ++ TISWI+ +I+IN Y + F S + + +I+F
Sbjct: 424 NEQIMGSFKIQPLVQTISWIVAALVIAINGYLMVDFF------SGAATNLILLVPVIIFA 477
Query: 480 LMAIYIASVIYLTFR 494
+ Y+ V+YL R
Sbjct: 478 I--AYVVFVLYLISR 490
>NRM2_ARATH (Q9C6B2) Metal transporter Nramp2 (AtNramp2)
Length = 530
Score = 298 bits (762), Expect = 3e-80
Identities = 176/432 (40%), Positives = 257/432 (58%), Gaps = 24/432 (5%)
Query: 68 VETDLQAGANHGYELLWLVLIGLIFALIIQSLAANLGVTTGKHLSEVCEVEYPLFVKYCL 127
+E DLQAGA GY LLWL++ L+IQ L+A +GV TG+HL+E+C EYP + +Y L
Sbjct: 88 LEGDLQAGAIAGYSLLWLLMWATAMGLLIQMLSARVGVATGRHLAELCRDEYPTWARYVL 147
Query: 128 WLLAEVAVIAADIPEVIGTAFALNILFN--IPLWAGVLLTGFSTLLLLSLQRFGVRKLEL 185
W +AE+A+I ADI EVIG+A A+ IL +PLWAGV++T L L L+ +GVRKLE
Sbjct: 148 WSMAELALIGADIQEVIGSAIAIQILSRGFLPLWAGVVITASDCFLFLFLENYGVRKLEA 207
Query: 186 LITILVFVMAGCFFAEMSYVNPPASGVLKGMFVPKLAGEGAVADAIALLGALIMPHNLFL 245
+ +L+ M F P ++ G+ +P+L+ + + A+ ++G +IMPHN+FL
Sbjct: 208 VFAVLIATMGLSFAWMFGETKPSGKELMIGILLPRLSSK-TIRQAVGVVGCVIMPHNVFL 266
Query: 246 HSALVLSRKV-PKSVRGINEACRYFLYESGFALFVAFLINVAMISVSGTVCSANDLSGDN 304
HSALV SRK+ PK + EA Y+L ES ALF++F+IN+ + T A G
Sbjct: 267 HSALVQSRKIDPKRKSRVQEALNYYLIESSVALFISFMINLFV-----TTVFAKGFYG-- 319
Query: 305 VERCNDLTLNSASFLLKNVLGRSSST---IYAIALLASGQSSTITGTYAGQYIMQGFLDI 361
E+ N++ L +A L+ G I+ I LLA+GQSSTITGTYAGQ+IM GFL++
Sbjct: 320 TEKANNIGLVNAGQYLQEKFGGGLLPILYIWGIGLLAAGQSSTITGTYAGQFIMGGFLNL 379
Query: 362 RMKRWKRNLMTRCIAIAPSLAVAIIGGSSGSSRLII--IASMILSFELPFALIPLLKFSS 419
R+K+W R ++TR AI P++ VAI+ +S +S ++ +++ S ++PFAL+PLL S
Sbjct: 380 RLKKWMRAVITRSCAIVPTMIVAIVFNTSEASLDVLNEWLNVLQSVQIPFALLPLLTLVS 439
Query: 420 SSTKMGPHKNSMIIITISWILGFGIISINVYYLSTAFVKWIIHSSLPKVANVFIGIIVFP 479
MG K I+ I+W + ++ IN Y L FV +V G+ V
Sbjct: 440 KEEIMGDFKIGPILQRIAWTVAALVMIINGYLLLDFFVS--------EVDGFLFGVTVCV 491
Query: 480 LMAIYIASVIYL 491
YIA ++YL
Sbjct: 492 WTTAYIAFIVYL 503
>NRM5_ARATH (Q9SN36) Metal transporter Nramp5 (AtNramp5)
Length = 530
Score = 293 bits (749), Expect = 1e-78
Identities = 172/432 (39%), Positives = 257/432 (58%), Gaps = 24/432 (5%)
Query: 68 VETDLQAGANHGYELLWLVLIGLIFALIIQSLAANLGVTTGKHLSEVCEVEYPLFVKYCL 127
+E DLQAGA GY LLWL+L + L++Q L+A +GV TG+HL+E+C EYP + + L
Sbjct: 90 IEGDLQAGAVAGYSLLWLLLWATLMGLLMQLLSARIGVATGRHLAEICRSEYPSWARILL 149
Query: 128 WLLAEVAVIAADIPEVIGTAFALNILFN--IPLWAGVLLTGFSTLLLLSLQRFGVRKLEL 185
W +AEVA+I ADI EVIG+A AL IL +P+W GV++T F L+ L++ G+RKLE
Sbjct: 150 WFMAEVALIGADIQEVIGSAIALQILTRGFLPIWVGVIITSFDCFLISYLEKCGMRKLEG 209
Query: 186 LITILVFVMAGCFFAEMSYVNPPASGVLKGMFVPKLAGEGAVADAIALLGALIMPHNLFL 245
L +L+ MA F + P + G+ +PKL G + +A+ ++G +I PHN+FL
Sbjct: 210 LFAVLIATMALSFAWMFNETKPSVEELFIGIIIPKL-GSKTIREAVGVVGCVITPHNVFL 268
Query: 246 HSALVLSRKV-PKSVRGINEACRYFLYESGFALFVAFLINVAMISVSGTVCSANDLSGDN 304
HSALV SRK PK + + EA Y+ ES ALFV+F+IN+ + T A G
Sbjct: 269 HSALVQSRKTDPKEINRVQEALNYYTIESSAALFVSFMINLFV-----TAVFAKGFYG-- 321
Query: 305 VERCNDLTLNSASFLLKNVLGRSSST---IYAIALLASGQSSTITGTYAGQYIMQGFLDI 361
++ + + L +A + L+ G I+ I LLA+GQSSTITGTYAGQ+IM+GFLD+
Sbjct: 322 TKQADSIGLVNAGYYLQEKYGGGVFPILYIWGIGLLAAGQSSTITGTYAGQFIMEGFLDL 381
Query: 362 RMKRWKRNLMTRCIAIAPSLAVAIIGGSSGSSRLII--IASMILSFELPFALIPLLKFSS 419
+M++W +TR AI P++ VAI+ +S S ++ +++ S ++PFA+IPLL S
Sbjct: 382 QMEQWLSAFITRSFAIVPTMFVAIMFNTSEGSLDVLNEWLNILQSMQIPFAVIPLLTMVS 441
Query: 420 SSTKMGPHKNSMIIITISWILGFGIISINVYYLSTAFVKWIIHSSLPKVANVFIGIIVFP 479
+ MG K + ++W + ++ IN Y L F + +V +G +VF
Sbjct: 442 NEHIMGVFKIGPSLEKLAWTVAVFVMMINGYLLLDFF--------MAEVEGFLVGFLVFG 493
Query: 480 LMAIYIASVIYL 491
+ YI+ +IYL
Sbjct: 494 GVVGYISFIIYL 505
>NRM3_ARATH (Q9SNV9) Metal transporter Nramp3 (AtNramp3)
Length = 509
Score = 293 bits (749), Expect = 1e-78
Identities = 174/426 (40%), Positives = 255/426 (59%), Gaps = 19/426 (4%)
Query: 68 VETDLQAGANHGYELLWLVLIGLIFALIIQSLAANLGVTTGKHLSEVCEVEYPLFVKYCL 127
+E DLQAGA GY LLWL++ L++Q L+A LGV TG+HL+E+C EYP + + L
Sbjct: 76 LEGDLQAGAVAGYSLLWLLMWATAMGLLVQLLSARLGVATGRHLAELCRDEYPTWARMVL 135
Query: 128 WLLAEVAVIAADIPEVIGTAFALNILFN--IPLWAGVLLTGFSTLLLLSLQRFGVRKLEL 185
W++AE+A+I +DI EVIG+A A+ IL N +PLWAGV++T + L L+ +G+RKLE
Sbjct: 136 WVMAELALIGSDIQEVIGSAIAIKILSNGILPLWAGVVITALDCFVFLFLENYGIRKLEA 195
Query: 186 LITILVFVMAGCFFAEMSYVNPPASGVLKGMFVPKLAGEGAVADAIALLGALIMPHNLFL 245
+ +L+ M F P S +L G+ VPKL+ + A+ ++G +IMPHN+FL
Sbjct: 196 VFAVLIATMGVSFAWMFGQAKPSGSELLIGILVPKLSSR-TIQKAVGVVGCIIMPHNVFL 254
Query: 246 HSALVLSRKVPKSVR-GINEACRYFLYESGFALFVAFLINVAMISVSGTVCSANDLSGDN 304
HSALV SR+V K + + EA Y+ ES ALF++FLIN+ + +V DL+
Sbjct: 255 HSALVQSREVDKRQKYRVQEALNYYTIESTIALFISFLINLFVTTVFAKGFYNTDLA--- 311
Query: 305 VERCNDLTLNSASFLLKNVLGRSSST---IYAIALLASGQSSTITGTYAGQYIMQGFLDI 361
N + L +A L+ G I+AI LLA+GQSSTITGTYAGQ+IM GFL+
Sbjct: 312 ----NSIGLVNAGQYLQEKYGGGVFPILYIWAIGLLAAGQSSTITGTYAGQFIMGGFLNF 367
Query: 362 RMKRWKRNLMTRCIAIAPSLAVAIIGGSSGSSRLII--IASMILSFELPFALIPLLKFSS 419
+MK+W R L+TR AI P++ VA++ SS ++ ++ +++ S ++PFALIPLL S
Sbjct: 368 KMKKWLRALITRSCAIIPTIIVALVFDSSEATLDVLNEWLNVLQSIQIPFALIPLLCLVS 427
Query: 420 SSTKMGPHKNSMIIITISWILGFGIISINVYYLSTAF---VKWIIHSSLPKVANVFIGII 476
MG K + TI+W++ +I IN Y L F V I+++ + G
Sbjct: 428 KEQIMGSFKIGPLYKTIAWLVAALVIMINGYLLLEFFSNEVSGIVYTGFVTLFTASYGAF 487
Query: 477 VFPLMA 482
+ L+A
Sbjct: 488 ILYLIA 493
>NRM2_MOUSE (P49282) Natural resistance-associated macrophage
protein 2 (NRAMP 2)
Length = 568
Score = 288 bits (736), Expect = 3e-77
Identities = 178/452 (39%), Positives = 266/452 (58%), Gaps = 46/452 (10%)
Query: 68 VETDLQAGANHGYELLWLVLIGLIFALIIQSLAANLGVTTGKHLSEVCEVEYPLFVKYCL 127
+E+DLQ+GA G++LLW++L+ I L++Q LAA LGV TG HL+EVC +YP + L
Sbjct: 90 IESDLQSGAVAGFKLLWVLLLATIVGLLLQRLAARLGVVTGLHLAEVCHRQYPKVPRIIL 149
Query: 128 WLLAEVAVIAADIPEVIGTAFALNILF--NIPLWAGVLLTGFSTLLLLSLQRFGVRKLEL 185
WL+ E+A+I +D+ EVIG+A A+N+L +P+W GVL+T T + L L ++G+RKLE
Sbjct: 150 WLMVELAIIGSDMQEVIGSAIAINLLSAGRVPVWGGVLITIADTFVFLFLDKYGLRKLEA 209
Query: 186 LITILVFVMAGCFFAEMSYVNPPASGVLKGMFVPKLAG--EGAVADAIALLGALIMPHNL 243
L+ +MA F E V P S VL+GMFVP G V A+ ++GA+IMPHN+
Sbjct: 210 FFGFLITIMALTFGYEYITVKPSQSQVLRGMFVPSCPGCRTPQVEQAVGIVGAVIMPHNM 269
Query: 244 FLHSALVLSRKVPK-SVRGINEACRYFLYESGFALFVAFLINVAMISVSG---------- 292
+LHSALV SR+V + + + + EA +YF ES ALFV+F+INV ++SV
Sbjct: 270 YLHSALVKSRQVNRANKQEVREANKYFFIESCIALFVSFIINVFVVSVFAEAFFEKTNKQ 329
Query: 293 --TVCSANDLSGDNVERCNDLTL----NSASFLLKNVLGRSSSTIYAIALLASGQSSTIT 346
VC N ++ ++ TL +L G ++ I+A+ +LA+GQSST+T
Sbjct: 330 VVEVCKNNSSPHADLFPSDNSTLAVDIYKGGVVLGCYFGPAALYIWAVGILAAGQSSTMT 389
Query: 347 GTYAGQYIMQGFLDIRMKRWKRNLMTRCIAIAPSLAVAIIGGSSGSSRLIIIASMILSFE 406
GTY+GQ++M+GFL+++ R+ R ++TR IAI P+L VA+ + + +++ S +
Sbjct: 390 GTYSGQFVMEGFLNLKWSRFARVILTRSIAIIPTLLVAVFQDVEHLTGMNDFLNVLQSLQ 449
Query: 407 LPFALIPLLKFSSSSTKMGPHKNSMIIITISWILGFGII-----SINVYYLSTAFVKWII 461
LPFALIP+L F+S M N I W + GI+ SIN+Y++ +V+ +
Sbjct: 450 LPFALIPILTFTSLRPVMSEFSNG-----IGWRIAGGILVLIVCSINMYFV-VVYVQELG 503
Query: 462 HSSLPKVANVFIGIIVFPLMAIYIASVIYLTF 493
H +L VA V SV YLTF
Sbjct: 504 HVALYVVAAV--------------VSVAYLTF 521
>NRM2_HUMAN (P49281) Natural resistance-associated macrophage
protein 2 (NRAMP 2) (Divalent metal transporter 1)
(DMT1) (OK/SW-cl.20)
Length = 568
Score = 287 bits (735), Expect = 4e-77
Identities = 176/450 (39%), Positives = 266/450 (59%), Gaps = 40/450 (8%)
Query: 68 VETDLQAGANHGYELLWLVLIGLIFALIIQSLAANLGVTTGKHLSEVCEVEYPLFVKYCL 127
+E+DLQ+GA G++LLW++L+ + L++Q LAA LGV TG HL+EVC +YP + L
Sbjct: 90 IESDLQSGAVAGFKLLWILLLATLVGLLLQRLAARLGVVTGLHLAEVCHRQYPKVPRVIL 149
Query: 128 WLLAEVAVIAADIPEVIGTAFALNILF--NIPLWAGVLLTGFSTLLLLSLQRFGVRKLEL 185
WL+ E+A+I +D+ EVIG+A A+N+L IPLW GVL+T T + L L ++G+RKLE
Sbjct: 150 WLMVELAIIGSDMQEVIGSAIAINLLSVGRIPLWGGVLITIADTFVFLFLDKYGLRKLEA 209
Query: 186 LITILVFVMAGCFFAEMSYVNPPASGVLKGMFVPKLAG--EGAVADAIALLGALIMPHNL 243
L+ +MA F E V P S VLKGMFVP +G + A+ ++GA+IMPHN+
Sbjct: 210 FFGFLITIMALTFGYEYVTVKPSQSQVLKGMFVPSCSGCRTPQIEQAVGIVGAVIMPHNM 269
Query: 244 FLHSALVLSRKVPK-SVRGINEACRYFLYESGFALFVAFLINVAMISVSGTVCSANDLSG 302
+LHSALV SR+V + + + + EA +YF ES ALFV+F+INV ++SV A G
Sbjct: 270 YLHSALVKSRQVNRNNKQEVREANKYFFIESCIALFVSFIINVFVVSV-----FAEAFFG 324
Query: 303 DNVERCNDLTLNSAS---------------------FLLKNVLGRSSSTIYAIALLASGQ 341
E+ ++ N++S +L G ++ I+A+ +LA+GQ
Sbjct: 325 KTNEQVVEVCTNTSSPHAGLFPKDNSTLAVDIYKGGVVLGCYFGPAALYIWAVGILAAGQ 384
Query: 342 SSTITGTYAGQYIMQGFLDIRMKRWKRNLMTRCIAIAPSLAVAIIGGSSGSSRLIIIASM 401
SST+TGTY+GQ++M+GFL+++ R+ R ++TR IAI P+L VA+ + + ++
Sbjct: 385 SSTMTGTYSGQFVMEGFLNLKWSRFARVVLTRSIAIIPTLLVAVFQDVEHLTGMNDFLNV 444
Query: 402 ILSFELPFALIPLLKFSSSSTKMGPHKNSMIIITISWILGFGIISINVYYLSTAFVKWII 461
+ S +LPFALIP+L F+S M N + IL I SIN+Y++ +V+ +
Sbjct: 445 LQSLQLPFALIPILTFTSLRPVMSDFANGLGWRIAGGILVLIICSINMYFV-VVYVRDLG 503
Query: 462 HSSLPKVANVFIGIIVFPLMAIYIASVIYL 491
H +L VA V + Y+ V YL
Sbjct: 504 HVALYVVAAV--------VSVAYLGFVFYL 525
>NRM2_RAT (O54902) Natural resistance-associated macrophage protein
2 (NRAMP 2) (Metal ion transporter DCT1)
Length = 568
Score = 284 bits (727), Expect = 4e-76
Identities = 178/451 (39%), Positives = 267/451 (58%), Gaps = 42/451 (9%)
Query: 68 VETDLQAGANHGYELLWLVLIGLIFALIIQSLAANLGVTTGKHLSEVCEVEYPLFVKYCL 127
+E+DLQ+GA G++LLW++L+ I L++Q LAA LGV TG HL+EVC +YP + L
Sbjct: 90 IESDLQSGAVAGFKLLWVLLLATIVGLLLQRLAARLGVVTGLHLAEVCHRQYPKVPRIIL 149
Query: 128 WLLAEVAVIAADIPEVIGTAFALNILF--NIPLWAGVLLTGFSTLLLLSLQRFGVRKLEL 185
WL+ E+A+I +D+ EVIG+A A+N+L +PL+ GVL+T T + L L ++G+RKLE
Sbjct: 150 WLMVELAIIGSDMQEVIGSAIAINLLSAGRVPLYGGVLITIADTFVFLFLDKYGLRKLEA 209
Query: 186 LITILVFVMAGCFFAEMSYVNPPASGVLKGMFVPKLAG--EGAVADAIALLGALIMPHNL 243
L+ +MA F E V P S VL+GMFVP +G V A+ ++GA+IMPHN+
Sbjct: 210 FFGFLITIMALTFGYEYVTVKPSQSQVLRGMFVPSCSGCHTPQVEQAVGIVGAVIMPHNM 269
Query: 244 FLHSALVLSRKVPK-SVRGINEACRYFLYESGFALFVAFLINVAMISVSGTVCSANDLSG 302
+LHSALV SR+V + + + + EA +YF ES ALFV+F+INV ++SV +
Sbjct: 270 YLHSALVKSRQVNRANKQEVREANKYFFIESCIALFVSFIINVFVVSVFAE-AFFEKTNE 328
Query: 303 DNVERCN-------DLTLNSASFLLKNV----------LGRSSSTIYAIALLASGQSSTI 345
VE C DL N S L ++ G ++ I+A+ +LA+GQSST+
Sbjct: 329 QVVEVCRNSSSPHADLFPNDNSTLAVDIYKGGVVLGCYFGPAALYIWAVGILAAGQSSTM 388
Query: 346 TGTYAGQYIMQGFLDIRMKRWKRNLMTRCIAIAPSLAVAIIGGSSGSSRLIIIASMILSF 405
TGTY+GQ++M+GFL+++ R+ R ++TR IAI P+L VA+ + + +++ S
Sbjct: 389 TGTYSGQFVMEGFLNLKWSRFARVILTRSIAIIPTLLVAVFQDVEHLTGMNDFLNVLQSL 448
Query: 406 ELPFALIPLLKFSSSSTKMGPHKNSMIIITISWILGFGII-----SINVYYLSTAFVKWI 460
+LPFALIP+L F+S M N I W + GI+ SIN+Y++ +V+ +
Sbjct: 449 QLPFALIPILTFTSLRPVMSEFSNG-----IGWRIAGGILVLLVCSINMYFV-VVYVQEL 502
Query: 461 IHSSLPKVANVFIGIIVFPLMAIYIASVIYL 491
H +L VA V + Y+ V YL
Sbjct: 503 GHVALYVVAAV--------VSVAYLGFVFYL 525
>NRM1_PIG (O77741) Natural resistance-associated macrophage protein
1 (NRAMP 1)
Length = 538
Score = 279 bits (713), Expect = 2e-74
Identities = 172/448 (38%), Positives = 258/448 (57%), Gaps = 31/448 (6%)
Query: 68 VETDLQAGANHGYELLWLVLIGLIFALIIQSLAANLGVTTGKHLSEVCEVEYPLFVKYCL 127
+++DLQAGA G++LLW++L + L+ Q LAA LGV TGK L E+C + YP + L
Sbjct: 75 IQSDLQAGAVAGFKLLWVLLWATVLGLLCQRLAARLGVVTGKDLGEICHLYYPKVPRTLL 134
Query: 128 WLLAEVAVIAADIPEVIGTAFALNILF--NIPLWAGVLLTGFSTLLLLSLQRFGVRKLEL 185
WL E+A++ +D+ EVIGTA A N+L IPLW GVL+T T L L +G+RKLE
Sbjct: 135 WLNMELAIVGSDMQEVIGTAIAFNLLSAGRIPLWGGVLITVVDTFFFLYLNNYGLRKLEA 194
Query: 186 LITILVFVMAGCFFAEMSYVNPPASGVLKGMFVPKLAGEGA--VADAIALLGALIMPHNL 243
L+ +MA F E P +L+G+F+P +G G + A+ ++GA+IMPHN+
Sbjct: 195 FFAFLIAIMAFTFGYEYVVARPAQGALLRGLFLPSCSGCGQPELLQAVGIVGAIIMPHNI 254
Query: 244 FLHSALVLSRKVPKSVR-GINEACRYFLYESGFALFVAFLINVAMISVSG---------- 292
+LHSALV SR+V ++ R I EA YFL ES ALFV+F IN+ +++V G
Sbjct: 255 YLHSALVKSREVDRTRREDIREANMYFLIESTIALFVSFFINLFVMAVFGQAFYQQTNQA 314
Query: 293 --TVCSANDLSG-DNVERCNDLTLN----SASFLLKNVLGRSSSTIYAIALLASGQSSTI 345
+C+ + L + N+LT+ +L + G ++ I+A+ LLA+GQSST+
Sbjct: 315 AFNICANSSLHDYAKIFPRNNLTVAVDFYQGGVILGCLFGPAALYIWAVGLLAAGQSSTM 374
Query: 346 TGTYAGQYIMQGFLDIRMKRWKRNLMTRCIAIAPSLAVAIIGGSSGSSRLIIIASMILSF 405
TGTYAGQ++M+GFL +R R+ R L+TR AI P+L VA+ S L + +++ S
Sbjct: 375 TGTYAGQFVMEGFLKLRWSRFARLLLTRSCAILPALLVAVFKELQDLSSLNDLLNVLQSL 434
Query: 406 ELPFALIPLLKFSSSSTKMGPHKNSMIIITISWILGFGIISINVYYLSTAFVKWIIHSSL 465
LPFA++P+L F+S M + + I+ + + +IN Y+L + SL
Sbjct: 435 LLPFAVLPILTFTSMPALMQEFASGRVNKVITSSIMLLVCAINFYFLVSYL------PSL 488
Query: 466 PKVANVFIGIIVFPLMAIYIASVIYLTF 493
P A + G++ L IY+ YL +
Sbjct: 489 PHPA--YFGLVAL-LAVIYLGLTTYLVW 513
>NRM1_CEREL (P56436) Natural resistance-associated macrophage
protein 1 (NRAMP 1)
Length = 548
Score = 277 bits (708), Expect = 6e-74
Identities = 170/448 (37%), Positives = 258/448 (56%), Gaps = 31/448 (6%)
Query: 68 VETDLQAGANHGYELLWLVLIGLIFALIIQSLAANLGVTTGKHLSEVCEVEYPLFVKYCL 127
+E+DLQAGA G++LLW++L + L+ Q LAA LGV TGK L EVC + YP + L
Sbjct: 75 IESDLQAGAVAGFKLLWVLLWATVLGLLCQRLAARLGVVTGKDLGEVCHLYYPKVPRILL 134
Query: 128 WLLAEVAVIAADIPEVIGTAFALNILF--NIPLWAGVLLTGFSTLLLLSLQRFGVRKLEL 185
WL E+A++ +D+ EVIGTA A ++L IPLW GVL+T T L L +G+RKLE
Sbjct: 135 WLTIELAIVGSDMQEVIGTAIAFSLLSAGRIPLWGGVLITIVDTFFFLFLDNYGLRKLEA 194
Query: 186 LITILVFVMAGCFFAEMSYVNPPASGVLKGMFVPKLAGEGA--VADAIALLGALIMPHNL 243
L+ +MA F E P +L+G+F+P AG G + A+ ++GA+IMPHN+
Sbjct: 195 FFGFLITIMALTFGYEYVVARPAQGALLQGLFLPSCAGCGQPELLQAVGIVGAIIMPHNI 254
Query: 244 FLHSALVLSRKVPKSVRG-INEACRYFLYESGFALFVAFLINVAMISVSG---------- 292
+LHS+LV SR+V +S R I EA YFL E+ AL V+FLIN+ +++V G
Sbjct: 255 YLHSSLVKSREVDRSRRADIREANMYFLIEATIALSVSFLINLFVMAVFGQAFYKQTNQA 314
Query: 293 --TVCSANDLSG-DNVERCNDLT----LNSASFLLKNVLGRSSSTIYAIALLASGQSSTI 345
+C+ + L + N+LT + +L + G ++ I+A+ LLA+GQSST+
Sbjct: 315 AFNICANSSLHDYATIFPRNNLTVAVDIYQGGVILGCLFGPAALYIWAVGLLAAGQSSTM 374
Query: 346 TGTYAGQYIMQGFLDIRMKRWKRNLMTRCIAIAPSLAVAIIGGSSGSSRLIIIASMILSF 405
TGTYAGQ++M+GFL +R R+ R L+TR AI P++ VA+ S L + +++ S
Sbjct: 375 TGTYAGQFVMEGFLKLRWSRFARVLLTRSCAILPTVLVAVFRDLRDLSGLNDLLNVLQSL 434
Query: 406 ELPFALIPLLKFSSSSTKMGPHKNSMIIITISWILGFGIISINVYYLSTAFVKWIIHSSL 465
LPFA++P+L F+S M N ++ IS + + ++N+Y+ + S +
Sbjct: 435 LLPFAVLPILTFTSMPAVMQEFANGLVSKVISSSIMVLVCAVNLYF---------VISYV 485
Query: 466 PKVANVFIGIIVFPLMAIYIASVIYLTF 493
P + + +V L A Y+ YL +
Sbjct: 486 PSLPHPDYFSLVALLAAAYLGLTTYLVW 513
>MVL_DROME (P49283) Malvolio protein
Length = 596
Score = 276 bits (707), Expect = 7e-74
Identities = 164/444 (36%), Positives = 254/444 (56%), Gaps = 28/444 (6%)
Query: 68 VETDLQAGANHGYELLWLVLIGLIFALIIQSLAANLGVTTGKHLSEVCEVEYPLFVKYCL 127
+E+D+Q+GA Y++LW++L + L++Q LAA LGV TG HL+E+C +Y ++ L
Sbjct: 97 IESDMQSGAAAKYKILWVLLWATVLGLLMQRLAARLGVVTGLHLAEMCYRQYKRLPRWIL 156
Query: 128 WLLAEVAVIAADIPEVIGTAFALNILFN--IPLWAGVLLTGFSTLLLLSLQRFGVRKLEL 185
W++ E+A+I +D+ EVIGTA A+ +L N +PLW GVL+T T L L ++G+RKLE
Sbjct: 157 WIMIEIAIIGSDMQEVIGTAIAIYLLSNKVVPLWGGVLITIVDTFTFLFLDKYGLRKLEF 216
Query: 186 LITILVFVMAGCFFAEMSYVNPPASGVLKGMFVPKLAG--EGAVADAIALLGALIMPHNL 243
L L+ +MA F E P VL+GMFVP + + A+ ++GA+IMPHNL
Sbjct: 217 LFGTLITIMAVSFGYEYIVSAPNQGEVLEGMFVPWCSNCNSNVLLQAVGVVGAVIMPHNL 276
Query: 244 FLHSALVLSRKVPK-SVRGINEACRYFLYESGFALFVAFLINVAMISVSG---------- 292
+LHSALV SR + + + ++EA YF E+ ALFV+F+IN+ +++V
Sbjct: 277 YLHSALVKSRDIDRRQTKKVSEANFYFFIEASVALFVSFIINLFVVAVFAHGMYGKTNND 336
Query: 293 --TVCSANDLSGDN----VERCN-----DLTLNSASFLLKNVLGRSSSTIYAIALLASGQ 341
VC + D V+ N D L L G + I+ + +LA+GQ
Sbjct: 337 VVEVCKDKSMYEDAKMSFVDNVNGTAIIDADLYKGGLFLGCTFGAVAMYIWGVGILAAGQ 396
Query: 342 SSTITGTYAGQYIMQGFLDIRMKRWKRNLMTRCIAIAPSLAVAIIGGSSGSSRLIIIASM 401
SST+TGTYAGQ+ M+GFL+++ RW R L+TRCIAI P+ +A+ + + I +
Sbjct: 397 SSTMTGTYAGQFSMEGFLNLQWPRWCRVLVTRCIAIIPTFCLAMFSKMEDLTSMNDILNA 456
Query: 402 ILSFELPFALIPLLKFSSSSTKMGPHKNSMIIITISWILGFGIISINVYYLSTAFVKWII 461
++S +LPFA IP + F+S + MG N + +S +L +I +N+Y++ I
Sbjct: 457 VMSLQLPFAAIPTIAFTSCAAIMGEFVNGLGNKIVSILLTIVVIGVNLYFVVVQVENMEI 516
Query: 462 HSSLPKVANVFIGIIVFPLMAIYI 485
L +A V I I++ L +Y+
Sbjct: 517 KGGL--LALVCIFAILYILFNLYL 538
>MNTH_ANASP (Q8ZSB0) Probable manganese transport protein mntH
Length = 442
Score = 275 bits (703), Expect = 2e-73
Identities = 156/396 (39%), Positives = 240/396 (60%), Gaps = 12/396 (3%)
Query: 70 TDLQAGANHGYELLWLVLIGLIFALIIQSLAANLGVTTGKHLSEVCEVEYPLFVKYCLWL 129
TD+ G+ GY LL ++L+ + A+++QSL LGV TG+ L++ C + V +CLW+
Sbjct: 51 TDIAGGSKFGYTLLTVILLSNLMAILLQSLCVRLGVATGRDLAQACRDYFSPKVSFCLWV 110
Query: 130 LAEVAVIAADIPEVIGTAFALNILFNIPLWAGVLLTGFSTLLLLSLQRFGVRKLELLITI 189
L E+A+ A D+ E++G+A AL +LF IPL GV +T L+LL LQ G R E L+ +
Sbjct: 111 LCEIAIAACDLAELLGSAIALQLLFVIPLIWGVCITALDVLVLLFLQHKGFRYTEALVIM 170
Query: 190 LVFVMAGCFFAEMSYVNPPASGVLKGMFVPK---LAGEGAVADAIALLGALIMPHNLFLH 246
LV + CF AE+ + P G+L G ++PK L + AI +LGA +MPHNL+LH
Sbjct: 171 LVATVGICFTAEILFSRPDMGGILLG-YLPKKEILQNPEMLYIAIGILGATVMPHNLYLH 229
Query: 247 SALVLSRKVPKSVRGINEACRYFLYESGFALFVAFLINVAMISVSGTVCSANDLSGDNVE 306
S++V +R + EA ++ +S FAL +A IN A++ VS + SG+
Sbjct: 230 SSIVQTRDWQPTTEKRWEAIKFGTIDSTFALSLALFINSAILIVS---AATFHFSGNQ-- 284
Query: 307 RCNDLTLNSASFLLKNVLGRS-SSTIYAIALLASGQSSTITGTYAGQYIMQGFLDIRMKR 365
N + A LL +LG S +S I+ IALLASGQSST+T T AGQ +M+GFL R+
Sbjct: 285 --NVAEIQDAYKLLSPLLGVSAASAIFGIALLASGQSSTLTATLAGQIVMEGFLQFRLPS 342
Query: 366 WKRNLMTRCIAIAPSLAVAIIGGSSGSSRLIIIASMILSFELPFALIPLLKFSSSSTKMG 425
W R L+TR +AI P+L I+ G + +S LI+++ +ILS +LPFA+IPL+ F+S+ MG
Sbjct: 343 WLRRLITRLLAIIPALITIILFGENSTSSLIVLSQVILSLQLPFAVIPLVMFTSNRRLMG 402
Query: 426 PHKNSMIIITISWILGFGIISINVYYLSTAFVKWII 461
N + + +++W++ I+ +N + L + W++
Sbjct: 403 EFVNPLWLKSLAWLVAIVIVGLNAWLLLQSLWGWLL 438
>NRM1_HUMAN (P49279) Natural resistance-associated macrophage
protein 1 (NRAMP 1)
Length = 550
Score = 275 bits (702), Expect = 3e-73
Identities = 170/448 (37%), Positives = 259/448 (56%), Gaps = 31/448 (6%)
Query: 68 VETDLQAGANHGYELLWLVLIGLIFALIIQSLAANLGVTTGKHLSEVCEVEYPLFVKYCL 127
+E+DLQAGA G++LLW++L + L+ Q LAA LGV TGK L EVC + YP + L
Sbjct: 78 IESDLQAGAVAGFKLLWVLLWATVLGLLCQRLAARLGVVTGKDLGEVCHLYYPKVPRTVL 137
Query: 128 WLLAEVAVIAADIPEVIGTAFALNILF--NIPLWAGVLLTGFSTLLLLSLQRFGVRKLEL 185
WL E+A++ +D+ EVIGTA A N+L IPLW GVL+T T L L +G+RKLE
Sbjct: 138 WLTIELAIVGSDMQEVIGTAIAFNLLSAGRIPLWGGVLITIVDTFFFLFLDNYGLRKLEA 197
Query: 186 LITILVFVMAGCFFAEMSYVNPPASGVLKGMFVPKLAGEG--AVADAIALLGALIMPHNL 243
+L+ +MA F E P +L+G+F+P G G + A+ ++GA+IMPHN+
Sbjct: 198 FFGLLITIMALTFGYEYVVARPEQGALLRGLFLPSCPGCGHPELLQAVGIVGAIIMPHNI 257
Query: 244 FLHSALVLSRKVPKSVRG-INEACRYFLYESGFALFVAFLINVAMISVSG---------- 292
+LHSALV SR++ ++ R I EA YFL E+ AL V+F+IN+ +++V G
Sbjct: 258 YLHSALVKSREIDRARRADIREANMYFLIEATIALSVSFIINLFVMAVFGQAFYQKTNQA 317
Query: 293 --TVCSANDLSG-DNVERCNDLT----LNSASFLLKNVLGRSSSTIYAIALLASGQSSTI 345
+C+ + L + N+ T + +L + G ++ I+AI LLA+GQSST+
Sbjct: 318 AFNICANSSLHDYAKIFPMNNATVAVDIYQGGVILGCLFGPAALYIWAIGLLAAGQSSTM 377
Query: 346 TGTYAGQYIMQGFLDIRMKRWKRNLMTRCIAIAPSLAVAIIGGSSGSSRLIIIASMILSF 405
TGTYAGQ++M+GFL +R R+ R L+TR AI P++ VA+ S L + +++ S
Sbjct: 378 TGTYAGQFVMEGFLRLRWSRFARVLLTRSCAILPTVLVAVFRDLRDLSGLNDLLNVLQSL 437
Query: 406 ELPFALIPLLKFSSSSTKMGPHKNSMIIITISWILGFGIISINVYYLSTAFVKWIIHSSL 465
LPFA++P+L F+S T M N ++ ++ + + +IN+Y++ + SL
Sbjct: 438 LLPFAVLPILTFTSMPTLMQEFANGLLNKVVTSSIMVLVCAINLYFVVSYL------PSL 491
Query: 466 PKVANVFIGIIVFPLMAIYIASVIYLTF 493
P A + G+ L A Y+ YL +
Sbjct: 492 PHPA--YFGLAAL-LAAAYLGLSTYLVW 516
>MNTH_LISIN (Q92BT1) Probable manganese transport protein mntH
Length = 448
Score = 275 bits (702), Expect = 3e-73
Identities = 155/387 (40%), Positives = 242/387 (62%), Gaps = 12/387 (3%)
Query: 70 TDLQAGANHGYELLWLVLIGLIFALIIQSLAANLGVTTGKHLSEVCEVEYPLFVKYCLWL 129
T + G+ GY LL ++LI I A+++QSLA+ LG+ TG+ L++ + + LW+
Sbjct: 63 TSIAGGSEFGYTLLSVILISNILAVLLQSLASKLGIVTGRDLAQASSDHFSKPFGFVLWI 122
Query: 130 LAEVAVIAADIPEVIGTAFALNILFNIPLWAGVLLTGFSTLLLLSLQRFGVRKLELLITI 189
LAE+A+IA DI EVIG+A ALN+LF IPL GV +T L+L LQ G R +E+++
Sbjct: 123 LAELAIIATDIAEVIGSAIALNLLFGIPLIWGVCITALDIFLVLFLQHKGFRYIEVIVIT 182
Query: 190 LVFVMAGCFFAEMSYVNPPASGVLKGMFVPK---LAGEGAVADAIALLGALIMPHNLFLH 246
L+ + CF AEM +P + KG F+P+ + + A+ +LGA +MPHNL+LH
Sbjct: 183 LMVTILVCFGAEMVMSHPDMQAIAKG-FIPQSEIVTNPAMLYIALGILGATVMPHNLYLH 241
Query: 247 SALVLSRKVPKSVRGINEACRYFLYESGFALFVAFLINVAMISVSGTVCSANDLSGDNVE 306
S++V +R+ ++ G EA R+ +S F+L +A LIN +++ ++ +A +G +
Sbjct: 242 SSIVQTRQYARTKEGKREAIRFSFIDSTFSLTIALLINASILILAA---AAFYTTGQH-- 296
Query: 307 RCNDLTLNSASFLLKNVLGRS-SSTIYAIALLASGQSSTITGTYAGQYIMQGFLDIRMKR 365
N + A LL LG S +ST++A+ALLASGQ+ST+TGT AGQ +M+GFL+IR+K
Sbjct: 297 --NVAGIEDAYKLLNPTLGSSIASTVFAVALLASGQNSTLTGTLAGQIVMEGFLNIRLKP 354
Query: 366 WKRNLMTRCIAIAPSLAVAIIGGSSGSSRLIIIASMILSFELPFALIPLLKFSSSSTKMG 425
R L+TR +AI P++ + + G++G + L+I + +ILS +L FA+IPL+ F+S KMG
Sbjct: 355 VVRRLLTRVLAIVPAVIITALYGANGINELLIFSQVILSMQLSFAVIPLVMFTSDKQKMG 414
Query: 426 PHKNSMIIITISWILGFGIISINVYYL 452
NS + +SW + I +N+Y L
Sbjct: 415 EFVNSPWLKIVSWSVAIFIAFLNIYLL 441
>NRM1_CANFA (Q9XT74) Natural resistance-associated macrophage
protein 1 (NRAMP 1)
Length = 547
Score = 274 bits (700), Expect = 5e-73
Identities = 169/448 (37%), Positives = 257/448 (56%), Gaps = 31/448 (6%)
Query: 68 VETDLQAGANHGYELLWLVLIGLIFALIIQSLAANLGVTTGKHLSEVCEVEYPLFVKYCL 127
+E+DLQAGA G++LLW++L + L+ Q LAA LGV TGK L E+C + YP + L
Sbjct: 75 IESDLQAGAVAGFKLLWVLLWATVLGLLCQRLAARLGVVTGKDLGEICHLYYPKVPRTLL 134
Query: 128 WLLAEVAVIAADIPEVIGTAFALNILF--NIPLWAGVLLTGFSTLLLLSLQRFGVRKLEL 185
WL E+A++ +D+ EVIGTA A ++L IPLW GVL+T T L L +G+RKLE
Sbjct: 135 WLTIELAIVGSDMQEVIGTAIAFSLLSAGRIPLWGGVLITIVDTFFFLFLDNYGLRKLEA 194
Query: 186 LITILVFVMAGCFFAEMSYVNPPASGVLKGMFVPKLAGEGA--VADAIALLGALIMPHNL 243
IL+ +MA F E P +L+G+ +P G G + A+ ++GA+IMPHN+
Sbjct: 195 FFGILITIMALTFGYEYVVARPAQVALLQGLLLPSCPGCGRPELLQAVGIVGAIIMPHNI 254
Query: 244 FLHSALVLSRKVPKSVR-GINEACRYFLYESGFALFVAFLINVAMISVSG---------- 292
+LHSALV SR++ +S R I EA YFL E+ AL V+F IN+ +++V G
Sbjct: 255 YLHSALVKSREIDRSRRPDIREANMYFLIEASIALSVSFFINLFVVAVFGQAFYQQTNEA 314
Query: 293 --TVCSANDLSG-DNVERCNDLTLN----SASFLLKNVLGRSSSTIYAIALLASGQSSTI 345
VC+ + L + N+LT+ +L V G ++ I+A+ LLA+GQSST+
Sbjct: 315 AFNVCANSSLHDYAKIFPRNNLTVEVDIYQGGVMLGCVFGPAALYIWAVGLLAAGQSSTM 374
Query: 346 TGTYAGQYIMQGFLDIRMKRWKRNLMTRCIAIAPSLAVAIIGGSSGSSRLIIIASMILSF 405
TGTYAGQ++M+GFL +R R+ R L+TR AI P++ V + S L + +++ S
Sbjct: 375 TGTYAGQFVMEGFLRLRWSRFARVLLTRSCAILPTVLVVVFRDLKDLSGLNDLLNVLQSL 434
Query: 406 ELPFALIPLLKFSSSSTKMGPHKNSMIIITISWILGFGIISINVYYLSTAFVKWIIHSSL 465
LPFA++P+L F+S M N + I+ + + +IN+Y++ +I+ L
Sbjct: 435 LLPFAVLPILTFTSMPALMQEFANGRLSKAITSFIMALVCAINLYFV-------VIY--L 485
Query: 466 PKVANVFIGIIVFPLMAIYIASVIYLTF 493
P + + I+V L +Y+ YL +
Sbjct: 486 PSLPHPAYFILVALLAIVYLGLTTYLVW 513
>MNTH_LISMO (Q8Y773) Probable manganese transport protein mntH
Length = 448
Score = 274 bits (700), Expect = 5e-73
Identities = 155/387 (40%), Positives = 241/387 (62%), Gaps = 12/387 (3%)
Query: 70 TDLQAGANHGYELLWLVLIGLIFALIIQSLAANLGVTTGKHLSEVCEVEYPLFVKYCLWL 129
T + G+ GY LL ++LI I A+++QSLA+ LG+ TG+ L++ + + LW+
Sbjct: 63 TSIAGGSEFGYTLLSVILISNILAVLLQSLASKLGIVTGRDLAQASSDHFSKPFGFVLWI 122
Query: 130 LAEVAVIAADIPEVIGTAFALNILFNIPLWAGVLLTGFSTLLLLSLQRFGVRKLELLITI 189
LAE+A+IA DI EVIG+A ALN+LF IPL GV +T L+L LQ G R +E+++
Sbjct: 123 LAELAIIATDIAEVIGSAIALNLLFGIPLIWGVCITALDIFLVLFLQHKGFRYIEVIVIT 182
Query: 190 LVFVMAGCFFAEMSYVNPPASGVLKGMFVPK---LAGEGAVADAIALLGALIMPHNLFLH 246
L+ + CF AEM +P + KG F+P+ + + A+ +LGA +MPHNL+LH
Sbjct: 183 LMVTILVCFGAEMVMSHPDMQAIAKG-FIPQSEIVTNPAMLYIALGILGATVMPHNLYLH 241
Query: 247 SALVLSRKVPKSVRGINEACRYFLYESGFALFVAFLINVAMISVSGTVCSANDLSGDNVE 306
S++V +R+ ++ G EA R+ +S F+L +A LIN +++ ++ +A +G +
Sbjct: 242 SSIVQTRQYARTKEGKKEAIRFSFIDSTFSLTIALLINASILILAA---AAFYTTGQH-- 296
Query: 307 RCNDLTLNSASFLLKNVLGRS-SSTIYAIALLASGQSSTITGTYAGQYIMQGFLDIRMKR 365
N + A LL LG S +ST++A+ALLASGQ+ST+TGT AGQ +M+GFL+IR+K
Sbjct: 297 --NVAGIEDAYKLLNPTLGSSIASTVFAVALLASGQNSTLTGTLAGQIVMEGFLNIRLKP 354
Query: 366 WKRNLMTRCIAIAPSLAVAIIGGSSGSSRLIIIASMILSFELPFALIPLLKFSSSSTKMG 425
R L+TR +AI P++ + + G++G + L+I + +ILS +L FA+IPL+ F+S KMG
Sbjct: 355 VVRRLLTRVLAIVPAVIITALYGANGINELLIFSQVILSMQLSFAVIPLVMFTSDKQKMG 414
Query: 426 PHKNSMIIITISWILGFGIISINVYYL 452
N + ISW + I +N+Y L
Sbjct: 415 EFVNPTWLKIISWAVAIFIAVLNIYLL 441
>NRML_CAEEL (Q21434) NRAMP-like transporter smf-1
Length = 557
Score = 273 bits (699), Expect = 6e-73
Identities = 165/442 (37%), Positives = 251/442 (56%), Gaps = 25/442 (5%)
Query: 68 VETDLQAGANHGYELLWLVLIGLIFALIIQSLAANLGVTTGKHLSEVCEVEYPLFVKYCL 127
+E+DLQ+GA Y+LLW++L I +++Q ++A LGV +GKH++EV YP + L
Sbjct: 76 IESDLQSGAQAAYKLLWVLLSAHIIGMLLQRMSARLGVVSGKHMAEVAYQFYPRLPRIIL 135
Query: 128 WLLAEVAVIAADIPEVIGTAFALNILFN--IPLWAGVLLTGFSTLLLLSLQRFGVRKLEL 185
WL+ E+A++ +D+ EVIGTA A+ +L +PL+ GV +T T L + R+G+RKLEL
Sbjct: 136 WLMIEIAIVCSDMQEVIGTAIAIFLLSKGFVPLYVGVFITILDTFTFLLIDRYGIRKLEL 195
Query: 186 LITILVFVMAGCFFAEMSYVNPPASGVLKGMFVPKLA--GEGAVADAIALLGALIMPHNL 243
+ L+ M F E V PP V+ GM VP A G+G AI+++GA+IMPHNL
Sbjct: 196 IFGFLILTMTVSFGYEFVVVKPPIGEVISGMVVPWCAGCGKGEFMQAISVVGAVIMPHNL 255
Query: 244 FLHSALVLSRKVP-KSVRGINEACRYFLYESGFALFVAFLINVAMISVSG---------- 292
+LHSALV SR+V K R + EA +YF ES ALF++F IN+ +++V
Sbjct: 256 YLHSALVKSRRVDRKDRRRVAEANKYFTLESAIALFLSFFINLFVVAVFAHGLYQKTNAD 315
Query: 293 --TVCSANDLSGDNVERCNDLTLNSASFLLKNVLGRSSSTIYAIALLASGQSSTITGTYA 350
+C A D N+ L G + I+ I + A+GQSST+TGTY
Sbjct: 316 VREMCIARHDIPDADIFPNNTEPVEGGIYLGCQFGAIAMFIWGIGIFAAGQSSTMTGTYT 375
Query: 351 GQYIMQGFLDIRMKRWKRNLMTRCIAIAPSLAVAIIG-GSSGSSRLIIIASMILSFELPF 409
GQ++M+GF+ I +WKR L+TR IAI P+L + G + + + + +LPF
Sbjct: 376 GQFVMEGFVKIEWPKWKRVLITRAIAITPTLVLTFYSQGVQNLTGMNDFLNCVQMIQLPF 435
Query: 410 ALIPLLKFSSSSTKMGPHKNSMIIITISWILGFGIISINVYYLSTAFVKWIIHSSLPKVA 469
ALIP++ F+SS M ++S + + I I+SINVY++S + S L +
Sbjct: 436 ALIPIITFTSSRKIMHDFRSSKVFQIFALITSALILSINVYFISD-----YVFSRLG--S 488
Query: 470 NVFIGIIVFPLMAIYIASVIYL 491
+I +++ P+ Y+ V+YL
Sbjct: 489 EWYIIMVLAPITFAYVLFVLYL 510
>NRM1_BUBBU (Q27946) Natural resistance-associated macrophage
protein 1 (NRAMP 1)
Length = 548
Score = 273 bits (699), Expect = 6e-73
Identities = 167/448 (37%), Positives = 257/448 (57%), Gaps = 31/448 (6%)
Query: 68 VETDLQAGANHGYELLWLVLIGLIFALIIQSLAANLGVTTGKHLSEVCEVEYPLFVKYCL 127
+E+DLQAGA G++LLW++L + L+ Q LAA LGV TGK L EVC + YP + L
Sbjct: 75 IESDLQAGAVAGFKLLWVLLWATVLGLLCQRLAARLGVVTGKDLGEVCHLYYPKVPRILL 134
Query: 128 WLLAEVAVIAADIPEVIGTAFALNILF--NIPLWAGVLLTGFSTLLLLSLQRFGVRKLEL 185
WL E+A++ +D+ EVIGTA A ++L IPLW GVL+T T L L +G+RKLE
Sbjct: 135 WLTIELAIVGSDMQEVIGTAIAFSLLSAGRIPLWGGVLITVVDTFFFLFLDNYGLRKLEA 194
Query: 186 LITILVFVMAGCFFAEMSYVNPPASGVLKGMFVPKLAGEGA--VADAIALLGALIMPHNL 243
L+ +MA F E P +L+G+F+P G G + A+ ++GA+IMPHN+
Sbjct: 195 FFGFLITIMALTFGYEYVVAQPAQGALLQGLFLPSCRGCGQPELLQAVGIIGAIIMPHNI 254
Query: 244 FLHSALVLSRKVPKSVRG-INEACRYFLYESGFALFVAFLINVAMISVSG---------- 292
+LHS+LV SR+V +S R I EA YFL E+ AL V+FLIN+ +++V G
Sbjct: 255 YLHSSLVKSREVDRSRRADIREANMYFLIEATIALSVSFLINLFVMAVFGQAFYKQTNQA 314
Query: 293 --TVCSANDLSG-DNVERCNDLT----LNSASFLLKNVLGRSSSTIYAIALLASGQSSTI 345
+C+ + L + N+LT + +L + G ++ I+A+ LLA+GQSST+
Sbjct: 315 AFNICAKSSLHDYAPIFPRNNLTVAVDIYQGGVILGCLFGPAALYIWAVGLLAAGQSSTM 374
Query: 346 TGTYAGQYIMQGFLDIRMKRWKRNLMTRCIAIAPSLAVAIIGGSSGSSRLIIIASMILSF 405
TGTYAGQ++M+GFL +R R+ R L+TR AI P++ +A+ S L + +++ S
Sbjct: 375 TGTYAGQFVMEGFLKLRWSRFARVLLTRSCAILPTVLLAVFRDLRDLSGLNDLLNVLQSL 434
Query: 406 ELPFALIPLLKFSSSSTKMGPHKNSMIIITISWILGFGIISINVYYLSTAFVKWIIHSSL 465
LPFA++P+L F+S M N ++ I+ + + ++N+Y+ + S +
Sbjct: 435 LLPFAVLPILTFTSMPALMQEFANGLVSKVITSSIMVLVCAVNLYF---------VISYV 485
Query: 466 PKVANVFIGIIVFPLMAIYIASVIYLTF 493
P + + +V L A Y+ YL +
Sbjct: 486 PSLPHPAYFSLVALLAAAYLGLTTYLVW 513
>NRM1_BOVIN (Q27981) Natural resistance-associated macrophage
protein 1 (NRAMP 1)
Length = 548
Score = 273 bits (699), Expect = 6e-73
Identities = 168/448 (37%), Positives = 256/448 (56%), Gaps = 31/448 (6%)
Query: 68 VETDLQAGANHGYELLWLVLIGLIFALIIQSLAANLGVTTGKHLSEVCEVEYPLFVKYCL 127
+E+DLQAGA G++LLW++L + L+ Q LAA LGV TGK L EVC + YP + L
Sbjct: 75 IESDLQAGAVAGFKLLWVLLWATVLGLLCQRLAARLGVVTGKDLGEVCHLYYPKVPRILL 134
Query: 128 WLLAEVAVIAADIPEVIGTAFALNILF--NIPLWAGVLLTGFSTLLLLSLQRFGVRKLEL 185
WL E+A++ +D+ EVIGTA A ++L IPLW GVL+T T L L +G+RKLE
Sbjct: 135 WLTIELAIVGSDMQEVIGTAIAFSLLSAGRIPLWGGVLITVVDTFFFLFLDNYGLRKLEA 194
Query: 186 LITILVFVMAGCFFAEMSYVNPPASGVLKGMFVPKLAGEGA--VADAIALLGALIMPHNL 243
L+ +MA F E P +L+G+F+P G G + A+ ++GA+IMPHN+
Sbjct: 195 FFGFLITIMALTFGYEYVVAQPAQGALLQGLFLPSCPGCGQPELLQAVGIIGAIIMPHNI 254
Query: 244 FLHSALVLSRKVPKSVRG-INEACRYFLYESGFALFVAFLINVAMISVSG---------- 292
+LHS+LV SR+V +S R I EA YFL E+ AL V+FLIN+ +++V G
Sbjct: 255 YLHSSLVKSREVDRSRRADIREANMYFLIEATIALSVSFLINLFVMAVFGQAFYKQTNQA 314
Query: 293 --TVCSANDLSG-DNVERCNDLT----LNSASFLLKNVLGRSSSTIYAIALLASGQSSTI 345
+C+ + L + N+LT + +L + G + I+A+ LLA+GQSST+
Sbjct: 315 AFNICADSSLHDYAPIFPRNNLTVAVDIYQGGVILGCLFGPPALYIWAVGLLAAGQSSTM 374
Query: 346 TGTYAGQYIMQGFLDIRMKRWKRNLMTRCIAIAPSLAVAIIGGSSGSSRLIIIASMILSF 405
TGTYAGQ++M+GFL +R R+ R L+TR AI P++ +A+ S L + +++ S
Sbjct: 375 TGTYAGQFVMEGFLKLRWSRFARVLLTRSCAILPTVLLAVFRDLRDLSGLNDLLNVLQSL 434
Query: 406 ELPFALIPLLKFSSSSTKMGPHKNSMIIITISWILGFGIISINVYYLSTAFVKWIIHSSL 465
LPFA++P+L F+S M N ++ I+ + + ++N+Y+ + S L
Sbjct: 435 LLPFAVLPILTFTSMPALMQEFANGLVSKVITSSIMVLVCAVNLYF---------VISYL 485
Query: 466 PKVANVFIGIIVFPLMAIYIASVIYLTF 493
P + + +V L A Y+ YL +
Sbjct: 486 PSLPHPAYFSLVALLAAAYLGLTTYLVW 513
Database: sprot
Posted date: Nov 25, 2004 10:54 AM
Number of letters in database: 59,974,054
Number of sequences in database: 164,201
Lambda K H
0.328 0.141 0.415
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 56,623,805
Number of Sequences: 164201
Number of extensions: 2223410
Number of successful extensions: 19042
Number of sequences better than 10.0: 202
Number of HSP's better than 10.0 without gapping: 176
Number of HSP's successfully gapped in prelim test: 26
Number of HSP's that attempted gapping in prelim test: 15417
Number of HSP's gapped (non-prelim): 1565
length of query: 541
length of database: 59,974,054
effective HSP length: 115
effective length of query: 426
effective length of database: 41,090,939
effective search space: 17504740014
effective search space used: 17504740014
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.7 bits)
S2: 68 (30.8 bits)
Medicago: description of AC140916.14