BLAST2 result
BLASTP 2.2.2 [Dec-14-2001]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= AC140915.5 - phase: 0
(598 letters)
Database: sprot
164,201 sequences; 59,974,054 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
GRR1_YEAST (P24814) Ubiquitin ligase complex F-box protein GRR1 89 2e-17
FXLK_HUMAN (Q96IG2) F-box/LRR-repeat protein 20 (F-box and leuci... 86 2e-16
FXLK_MOUSE (Q9CZV8) F-box/LRR-repeat protein 20 (F-box and leuci... 86 3e-16
POF2_SCHPO (O74783) F-box/LRR-repeat protein 2 (F-box and leucin... 80 2e-14
FL2_HUMAN (Q9UKC9) F-box/LRR-repeat protein 2 (F-box and leucine... 80 2e-14
FL2_MOUSE (Q8BH16) F-box/LRR-repeat protein 2 (F-box and leucine... 77 2e-13
FXL4_HUMAN (Q9UKA2) F-box/LRR-repeat protein 4 (F-box and leucin... 75 5e-13
YKK7_CAEEL (P34284) Hypothetical F-box/LRR-repeat protein C02F5.... 69 3e-11
FXL7_HUMAN (Q9UJT9) F-box/LRR-repeat protein 7 (F-box and leucin... 67 1e-10
FXLK_RAT (Q9QZH7) F-box/LRR-repeat protein 20 (F-box and leucine... 65 4e-10
FXLE_MOUSE (Q8BID8) F-box/LRR-repeat protein 14 (F-box and leuci... 62 6e-09
FXLE_HUMAN (Q8N1E6) F-box/LRR-repeat protein 14 (F-box and leuci... 62 6e-09
FX37_MOUSE (Q91W61) F-box only protein 37 (F-box/LRR-repeat prot... 61 1e-08
FXLH_MOUSE (Q9QZN1) F-box/LRR-repeat protein 17 (F-box and leuci... 59 5e-08
FX37_HUMAN (Q9H469) F-box only protein 37 (F-box/LRR-repeat prot... 58 6e-08
FXLH_HUMAN (Q9UF56) F-box/LRR-repeat protein 17 (F-box and leuci... 58 8e-08
FXLG_HUMAN (Q8N461) F-box/LRR-repeat protein 16 (F-box and leuci... 55 4e-07
SKP2_HUMAN (Q13309) S-phase kinase-associated protein 2 (F-box p... 50 2e-05
SKP2_MOUSE (Q9Z0Z3) S-phase kinase-associated protein 2 (F-box p... 48 6e-05
SHO2_MOUSE (O88520) Leucine-rich repeat protein SHOC-2 (Ras-bind... 46 3e-04
>GRR1_YEAST (P24814) Ubiquitin ligase complex F-box protein GRR1
Length = 1151
Score = 89.4 bits (220), Expect = 2e-17
Identities = 82/382 (21%), Positives = 175/382 (45%), Gaps = 51/382 (13%)
Query: 204 IKLRKVNLSYHG-YLNGTLLSHLFKNCKFLQEVILLRCEQLTIAGVDLALLQKPTLTSLS 262
+ ++++N S+ G Y++ T L++ F CK L+ + L+ C+ +T + L L S+
Sbjct: 388 LMIKRLNFSFVGDYMHDTELNY-FVGCKNLERLTLVFCKHITSVPISAVLRGCKFLQSVD 446
Query: 263 ITCTVTTGLEHLTSHFIDSLLSLKGLTSLLLTGF------RISDQFLSSIAMESLPLRRL 316
IT G+ ++ D+L + + GF ++ L + + S L+R+
Sbjct: 447 IT-----GIRDVSDDVFDTLATY----CPRVQGFYVPQARNVTFDSLRNFIVHSPMLKRI 497
Query: 317 VLSYCPGYTYSGISFLLSKSKRIQHLDLQYTDFLNDHCVAELSLFLGDLLSLNLGNCRLL 376
++ + L +K + +D+ + + D + +L L L + + +
Sbjct: 498 KITANNNMNDELVELLANKCPLLVEVDITLSPNVTDSSLLKLLTRLVQLREFRITHNTNI 557
Query: 377 TVSTFFAL---ITNCPSLTEINMNRTNIQGTTIPNSLMDRLVN--PQFKSLFLASAACLE 431
T + F L + + PSL I+++ I + ++ +VN P+ +++FL + +
Sbjct: 558 TDNLFQELSKVVDDMPSLRLIDLSGCE----NITDKTIESIVNLAPKLRNVFLGKCSRIT 613
Query: 432 DQNIIMFAALFPNLQQLHLSCSYNITEEGIRPLLESCRKIRHLNLTCLSLKSLGTNFDLP 491
D ++ + L NLQ +H +NIT+ G+R L SC +I++++ C + + T ++L
Sbjct: 614 DASLFQLSKLGKNLQTVHFGHCFNITDNGVRALFHSCTRIQYVDFACCTNLTNRTLYELA 673
Query: 492 DLEVLNLTNTEVDDEALYIISNRCPALLQLVLLRCDYITDKGVMHVVN---NCTQLREIN 548
DL P L ++ L++C +TD+G++++V+ L ++
Sbjct: 674 DL----------------------PKLKRIGLVKCTQMTDEGLLNMVSLRGRNDTLERVH 711
Query: 549 LDGCPNVQAKVVASMVVSRPSL 570
L C N+ + +++S P L
Sbjct: 712 LSYCSNLTIYPIYELLMSCPRL 733
Score = 50.8 bits (120), Expect = 1e-05
Identities = 56/263 (21%), Positives = 115/263 (43%), Gaps = 36/263 (13%)
Query: 339 IQHLDLQYT-DFLNDHCVAELSLFLG--DLLSLNLGNCRLLTVSTFFALITNCPSLTEIN 395
I+ L+ + D+++D EL+ F+G +L L L C+ +T A++ C L ++
Sbjct: 390 IKRLNFSFVGDYMHD---TELNYFVGCKNLERLTLVFCKHITSVPISAVLRGCKFLQSVD 446
Query: 396 MNRTNIQGTTIPNSLMDRLVN--PQFKSLFLASAACLEDQNIIMFAALFPNLQQLHLSCS 453
+ T I+ + + + D L P+ + ++ A + ++ F P L+++ ++ +
Sbjct: 447 I--TGIRD--VSDDVFDTLATYCPRVQGFYVPQARNVTFDSLRNFIVHSPMLKRIKITAN 502
Query: 454 YNITEEGIRPLLESCRKIRHLNLTCLSLKSLGTNFDLPDLEVLNLTNTEVDDEALYIISN 513
N+ +E + L C + +++T + V D +L +
Sbjct: 503 NNMNDELVELLANKCPLLVEVDITL---------------------SPNVTDSSLLKLLT 541
Query: 514 RCPALLQLVLLRCDYITD---KGVMHVVNNCTQLREINLDGCPNVQAKVVASMVVSRPSL 570
R L + + ITD + + VV++ LR I+L GC N+ K + S+V P L
Sbjct: 542 RLVQLREFRITHNTNITDNLFQELSKVVDDMPSLRLIDLSGCENITDKTIESIVNLAPKL 601
Query: 571 RKIHVPPNFPLSDRNRKLFSRHG 593
R + + ++D + S+ G
Sbjct: 602 RNVFLGKCSRITDASLFQLSKLG 624
Score = 40.8 bits (94), Expect = 0.010
Identities = 54/270 (20%), Positives = 109/270 (40%), Gaps = 65/270 (24%)
Query: 157 SLNSTDIHLIADTFPLLEELDLAYPSKIINHTHATFSTGLEALSLALIKLRKVNLSYHGY 216
++N + L+A+ PLL E+D+ + + + L L L++LR+ ++++
Sbjct: 504 NMNDELVELLANKCPLLVEVDITLSPNVTD-------SSLLKLLTRLVQLREFRITHNTN 556
Query: 217 LNGTLLSHLFKNCKFLQEVILLRCEQLTIAGVDLALLQKPTLTSLSITCTVTTGLEHLTS 276
+ L L K + ++ LR +DL +G E++T
Sbjct: 557 ITDNLFQEL---SKVVDDMPSLRL-------IDL------------------SGCENITD 588
Query: 277 HFIDSLLSLKGLTSLLLTG--FRISDQFLSSIAMESLPLRRLVLSYCPGYTYSGISFLLS 334
I+S+++L + G RI+D L ++ L+ + +C T +G+ L
Sbjct: 589 KTIESIVNLAPKLRNVFLGKCSRITDASLFQLSKLGKNLQTVHFGHCFNITDNGVRALFH 648
Query: 335 KSKRIQHLDLQYTDFLNDHCVAELSLF------------------LGDLLSL-------- 368
RIQ++D L + + EL+ L +++SL
Sbjct: 649 SCTRIQYVDFACCTNLTNRTLYELADLPKLKRIGLVKCTQMTDEGLLNMVSLRGRNDTLE 708
Query: 369 --NLGNCRLLTVSTFFALITNCPSLTEINM 396
+L C LT+ + L+ +CP L+ +++
Sbjct: 709 RVHLSYCSNLTIYPIYELLMSCPRLSHLSL 738
>FXLK_HUMAN (Q96IG2) F-box/LRR-repeat protein 20 (F-box and
leucine-rich repeat protein 20) (F-box/LRR-repeat
protein 2-like)
Length = 436
Score = 86.3 bits (212), Expect = 2e-16
Identities = 76/279 (27%), Positives = 112/279 (39%), Gaps = 44/279 (15%)
Query: 313 LRRLVLSYCPGYTYSGISFLLSKSKRIQHLDLQYTDFLNDHCVAELSLFLGDLLSLNLGN 372
LR+L L C G + + + I+ L+L D LS F L L+L +
Sbjct: 93 LRKLSLRGCLGVGDNALRTFAQNCRNIEVLNLNGCTKTTDATCTSLSKFCSKLRHLDLAS 152
Query: 373 CRLLTVSTFFALITNCPSLTEINMNRTNIQGTTIPNSLMDRLVNP--QFKSLFLASAACL 430
C +T + AL CP L ++N++ + + + LV K+LFL L
Sbjct: 153 CTSITNMSLKALSEGCPLLEQLNISWCD----QVTKDGIQALVRGCGGLKALFLKGCTQL 208
Query: 431 EDQNIIMFAALFPNLQQLHLSCSYNITEEGIRPLLESCRKIRHL------NLTCLSLKSL 484
ED+ + A P L L+L IT+EG+ + C K++ L N+T L +L
Sbjct: 209 EDEALKYIGAHCPELVTLNLQTCLQITDEGLITICRGCHKLQSLCASGCSNITDAILNAL 268
Query: 485 GTNFDLPDLEVLNLTN---------------------------TEVDDEALYIISNRCPA 517
G N P L +L + ++ D L +S CP
Sbjct: 269 GQN--CPRLRILEVARCSQLTDVGFTTLARNCHELEKMDLEECVQITDSTLIQLSIHCPR 326
Query: 518 LLQLVLLRCDYITDKGVMHVVNNC---TQLREINLDGCP 553
L L L C+ ITD G+ H+ N QL I LD CP
Sbjct: 327 LQVLSLSHCELITDDGIRHLGNGACAHDQLEVIELDNCP 365
Score = 69.3 bits (168), Expect = 3e-11
Identities = 57/224 (25%), Positives = 100/224 (44%), Gaps = 29/224 (12%)
Query: 363 GDLLSLNLGNCRLLTVSTFFALITNCPSLTEINMN---RTNIQGTTIPNSLMDRLVNPQF 419
G L L+L C + + NC ++ +N+N +T T + +L
Sbjct: 91 GFLRKLSLRGCLGVGDNALRTFAQNCRNIEVLNLNGCTKTTDATCTSLSKFCSKL----- 145
Query: 420 KSLFLASAACLEDQNIIMFAALFPNLQQLHLSCSYNITEEGIRPLLESCRKIRHLNLTCL 479
+ L LAS + + ++ + P L+QL++S +T++GI+ L+ C L L
Sbjct: 146 RHLDLASCTSITNMSLKALSEGCPLLEQLNISWCDQVTKDGIQALVRGCG-----GLKAL 200
Query: 480 SLKSLGTNFDLPDLEVLNLTNTEVDDEALYIISNRCPALLQLVLLRCDYITDKGVMHVVN 539
LK T+++DEAL I CP L+ L L C ITD+G++ +
Sbjct: 201 FLKGC----------------TQLEDEALKYIGAHCPELVTLNLQTCLQITDEGLITICR 244
Query: 540 NCTQLREINLDGCPNVQAKVVASMVVSRPSLRKIHVPPNFPLSD 583
C +L+ + GC N+ ++ ++ + P LR + V L+D
Sbjct: 245 GCHKLQSLCASGCSNITDAILNALGQNCPRLRILEVARCSQLTD 288
Score = 59.7 bits (143), Expect = 2e-08
Identities = 68/291 (23%), Positives = 116/291 (39%), Gaps = 26/291 (8%)
Query: 121 LTSLNLSNQLILPANGLRAFSQNITTLTSLICSNLISLNSTDIHLIADTFPLLEELDLAY 180
L L+L L + N LR F+QN + L + ++ L LDLA
Sbjct: 93 LRKLSLRGCLGVGDNALRTFAQNCRNIEVLNLNGCTKTTDATCTSLSKFCSKLRHLDLAS 152
Query: 181 PSKIINHTHATFSTGLEALSLALIKLRKVNLSYHGYLNGTLLSHLFKNCKFLQEVILLRC 240
+ I N + L+ALS L ++N+S+ + + L + C L+ + L C
Sbjct: 153 CTSITNMS-------LKALSEGCPLLEQLNISWCDQVTKDGIQALVRGCGGLKALFLKGC 205
Query: 241 EQLTIAGVDLALLQKPTLTSLSITCTVTTGLEHLTSHFIDSLLSLKGLTSLLLTGF-RIS 299
QL + P L +L++ T L+ I L SL +G I+
Sbjct: 206 TQLEDEALKYIGAHCPELVTLNLQ----TCLQITDEGLITICRGCHKLQSLCASGCSNIT 261
Query: 300 DQFLSSIAMESLPLRRLVLSYCPGYTYSGISFLLSKSKRIQHLDLQYTDFLNDHCVAELS 359
D L+++ LR L ++ C T G + L ++ +DL+ + D + +LS
Sbjct: 262 DAILNALGQNCPRLRILEVARCSQLTDVGFTTLARNCHELEKMDLEECVQITDSTLIQLS 321
Query: 360 LFLGDLLSLNLGNCRLLTVSTFFAL--------------ITNCPSLTEINM 396
+ L L+L +C L+T L + NCP +T+ ++
Sbjct: 322 IHCPRLQVLSLSHCELITDDGIRHLGNGACAHDQLEVIELDNCPLITDASL 372
Score = 33.9 bits (76), Expect = 1.2
Identities = 23/97 (23%), Positives = 42/97 (42%), Gaps = 2/97 (2%)
Query: 502 EVDDEALYIISNRCPALLQLVLLR-CDYITDKGVMHVVNNCTQLREINLDGCPNVQAKVV 560
+++ + IS RC L+ + LR C + D + NC + +NL+GC
Sbjct: 76 DIEGRVVENISKRCGGFLRKLSLRGCLGVGDNALRTFAQNCRNIEVLNLNGCTKTTDATC 135
Query: 561 ASMVVSRPSLRKIHVPPNFPLSDRNRKLFSRHGCLLV 597
S+ LR + + +++ + K S GC L+
Sbjct: 136 TSLSKFCSKLRHLDLASCTSITNMSLKALS-EGCPLL 171
Score = 32.3 bits (72), Expect = 3.6
Identities = 36/157 (22%), Positives = 66/157 (41%), Gaps = 8/157 (5%)
Query: 93 KLTSLDLSYYYGDLDALLTQIS-SFPMLKLTSLNLSNQLILPANGLRAFSQNITTLTSLI 151
KL SL S DA+L + + P L++ + +QL G ++N L +
Sbjct: 248 KLQSLCASGCSNITDAILNALGQNCPRLRILEVARCSQLT--DVGFTTLARNCHELEKMD 305
Query: 152 CSNLISLNSTDIHLIADTFPLLEELDLAYPSKIINHTHATFSTGLEALSLALIKLRKVNL 211
+ + + + ++ P L+ L L++ I + G + A +L + L
Sbjct: 306 LEECVQITDSTLIQLSIHCPRLQVLSLSHCELITDDGIRHLGNG----ACAHDQLEVIEL 361
Query: 212 SYHGYLNGTLLSHLFKNCKFLQEVILLRCEQLTIAGV 248
+ L HL K+C L+ + L C+Q+T AG+
Sbjct: 362 DNCPLITDASLEHL-KSCHSLERIELYDCQQITRAGI 397
>FXLK_MOUSE (Q9CZV8) F-box/LRR-repeat protein 20 (F-box and
leucine-rich repeat protein 20) (F-box/LRR-repeat
protein 2-like)
Length = 436
Score = 85.9 bits (211), Expect = 3e-16
Identities = 76/279 (27%), Positives = 111/279 (39%), Gaps = 44/279 (15%)
Query: 313 LRRLVLSYCPGYTYSGISFLLSKSKRIQHLDLQYTDFLNDHCVAELSLFLGDLLSLNLGN 372
LR+L L C G + + + I+ L L D LS F L L+L +
Sbjct: 93 LRKLSLRGCLGVGDNALRTFAQNCRNIEVLSLNGCTKTTDATCTSLSKFCSKLRHLDLAS 152
Query: 373 CRLLTVSTFFALITNCPSLTEINMNRTNIQGTTIPNSLMDRLVNP--QFKSLFLASAACL 430
C +T + AL CP L ++N++ + + + LV K+LFL L
Sbjct: 153 CTSITNMSLKALSEGCPLLEQLNISWCD----QVTKDGIQALVRGCGGLKALFLKGCTQL 208
Query: 431 EDQNIIMFAALFPNLQQLHLSCSYNITEEGIRPLLESCRKIRHL------NLTCLSLKSL 484
ED+ + A P L L+L IT+EG+ + C K++ L N+T L +L
Sbjct: 209 EDEALKYIGAHCPELVTLNLQTCLQITDEGLITICRGCHKLQSLCASGCSNITDAILNAL 268
Query: 485 GTNFDLPDLEVLNLTN---------------------------TEVDDEALYIISNRCPA 517
G N P L +L + ++ D L +S CP
Sbjct: 269 GQN--CPRLRILEVARCSQLTDVGFTTLARNCHELEKMDLEECVQITDSTLIQLSIHCPR 326
Query: 518 LLQLVLLRCDYITDKGVMHVVNNC---TQLREINLDGCP 553
L L L C+ ITD G+ H+ N QL I LD CP
Sbjct: 327 LQVLSLSHCELITDDGIRHLGNGACAHDQLEVIELDNCP 365
Score = 67.4 bits (163), Expect = 1e-10
Identities = 56/224 (25%), Positives = 100/224 (44%), Gaps = 29/224 (12%)
Query: 363 GDLLSLNLGNCRLLTVSTFFALITNCPSLTEINMN---RTNIQGTTIPNSLMDRLVNPQF 419
G L L+L C + + NC ++ +++N +T T + +L
Sbjct: 91 GFLRKLSLRGCLGVGDNALRTFAQNCRNIEVLSLNGCTKTTDATCTSLSKFCSKL----- 145
Query: 420 KSLFLASAACLEDQNIIMFAALFPNLQQLHLSCSYNITEEGIRPLLESCRKIRHLNLTCL 479
+ L LAS + + ++ + P L+QL++S +T++GI+ L+ C L L
Sbjct: 146 RHLDLASCTSITNMSLKALSEGCPLLEQLNISWCDQVTKDGIQALVRGCG-----GLKAL 200
Query: 480 SLKSLGTNFDLPDLEVLNLTNTEVDDEALYIISNRCPALLQLVLLRCDYITDKGVMHVVN 539
LK T+++DEAL I CP L+ L L C ITD+G++ +
Sbjct: 201 FLKGC----------------TQLEDEALKYIGAHCPELVTLNLQTCLQITDEGLITICR 244
Query: 540 NCTQLREINLDGCPNVQAKVVASMVVSRPSLRKIHVPPNFPLSD 583
C +L+ + GC N+ ++ ++ + P LR + V L+D
Sbjct: 245 GCHKLQSLCASGCSNITDAILNALGQNCPRLRILEVARCSQLTD 288
Score = 60.1 bits (144), Expect = 2e-08
Identities = 68/291 (23%), Positives = 116/291 (39%), Gaps = 26/291 (8%)
Query: 121 LTSLNLSNQLILPANGLRAFSQNITTLTSLICSNLISLNSTDIHLIADTFPLLEELDLAY 180
L L+L L + N LR F+QN + L + ++ L LDLA
Sbjct: 93 LRKLSLRGCLGVGDNALRTFAQNCRNIEVLSLNGCTKTTDATCTSLSKFCSKLRHLDLAS 152
Query: 181 PSKIINHTHATFSTGLEALSLALIKLRKVNLSYHGYLNGTLLSHLFKNCKFLQEVILLRC 240
+ I N + L+ALS L ++N+S+ + + L + C L+ + L C
Sbjct: 153 CTSITNMS-------LKALSEGCPLLEQLNISWCDQVTKDGIQALVRGCGGLKALFLKGC 205
Query: 241 EQLTIAGVDLALLQKPTLTSLSITCTVTTGLEHLTSHFIDSLLSLKGLTSLLLTGF-RIS 299
QL + P L +L++ T L+ I L SL +G I+
Sbjct: 206 TQLEDEALKYIGAHCPELVTLNLQ----TCLQITDEGLITICRGCHKLQSLCASGCSNIT 261
Query: 300 DQFLSSIAMESLPLRRLVLSYCPGYTYSGISFLLSKSKRIQHLDLQYTDFLNDHCVAELS 359
D L+++ LR L ++ C T G + L ++ +DL+ + D + +LS
Sbjct: 262 DAILNALGQNCPRLRILEVARCSQLTDVGFTTLARNCHELEKMDLEECVQITDSTLIQLS 321
Query: 360 LFLGDLLSLNLGNCRLLTVSTFFAL--------------ITNCPSLTEINM 396
+ L L+L +C L+T L + NCP +T+ ++
Sbjct: 322 IHCPRLQVLSLSHCELITDDGIRHLGNGACAHDQLEVIELDNCPLITDASL 372
Score = 57.8 bits (138), Expect = 8e-08
Identities = 80/337 (23%), Positives = 133/337 (38%), Gaps = 40/337 (11%)
Query: 206 LRKVNLSYHGYLNGTLLSHLFKNCKFLQEVILLRCEQLTIAGVDLALLQKPTLTSLSITC 265
LRK++L + L +NC+ ++ + L C + T A T TSLS C
Sbjct: 93 LRKLSLRGCLGVGDNALRTFAQNCRNIEVLSLNGCTKTTDA----------TCTSLSKFC 142
Query: 266 TVTTGLEHLTSHFIDSLLSLKGLTSLLLTGFRISDQFLSSIAMESLPL-RRLVLSYCPGY 324
+ L HL L S +T++ L E PL +L +S+C
Sbjct: 143 SK---LRHL------DLASCTSITNMSLKALS-----------EGCPLLEQLNISWCDQV 182
Query: 325 TYSGISFLLSKSKRIQHLDLQYTDFLNDHCVAELSLFLGDLLSLNLGNCRLLTVSTFFAL 384
T GI L+ ++ L L+ L D + + +L++LNL C +T +
Sbjct: 183 TKDGIQALVRGCGGLKALFLKGCTQLEDEALKYIGAHCPELVTLNLQTCLQITDEGLITI 242
Query: 385 ITNCPSLTEINMNRTNIQGTTIPNSLMDRLVNPQFKSLFLASAACLEDQNIIMFAALFPN 444
C L + + + I N+L P+ + L +A + L D A
Sbjct: 243 CRGCHKLQSLCASGCSNITDAILNALGQNC--PRLRILEVARCSQLTDVGFTTLARNCHE 300
Query: 445 LQQLHLSCSYNITEEGIRPLLESCRKIRHLNLTCLSL------KSLGTNFDLPD-LEVLN 497
L+++ L IT+ + L C +++ L+L+ L + LG D LEV+
Sbjct: 301 LEKMDLEECVQITDSTLIQLSIHCPRLQVLSLSHCELITDDGIRHLGNGACAHDQLEVIE 360
Query: 498 LTNTEVDDEALYIISNRCPALLQLVLLRCDYITDKGV 534
L N + +A CP+ ++ L C IT G+
Sbjct: 361 LDNCPLITDASLEHLKSCPSFERIELYDCQQITRAGI 397
Score = 32.0 bits (71), Expect = 4.7
Identities = 22/97 (22%), Positives = 42/97 (42%), Gaps = 2/97 (2%)
Query: 502 EVDDEALYIISNRCPALLQLVLLR-CDYITDKGVMHVVNNCTQLREINLDGCPNVQAKVV 560
+++ + IS RC L+ + LR C + D + NC + ++L+GC
Sbjct: 76 DIEGRVVENISKRCGGFLRKLSLRGCLGVGDNALRTFAQNCRNIEVLSLNGCTKTTDATC 135
Query: 561 ASMVVSRPSLRKIHVPPNFPLSDRNRKLFSRHGCLLV 597
S+ LR + + +++ + K S GC L+
Sbjct: 136 TSLSKFCSKLRHLDLASCTSITNMSLKALS-EGCPLL 171
>POF2_SCHPO (O74783) F-box/LRR-repeat protein 2 (F-box and
leucine-rich repeat protein 2) (F-box protein pof2)
Length = 463
Score = 80.1 bits (196), Expect = 2e-14
Identities = 99/414 (23%), Positives = 178/414 (42%), Gaps = 72/414 (17%)
Query: 96 SLDLSYYYGDLDAL-LTQISSFPMLK----------LTSLNLSN--QLILPANGLRAFSQ 142
S D+SYY+ L L +++ F K ++ LNLS ++ P G + Q
Sbjct: 60 SKDVSYYFRYLRKLNCSRVRKFLTDKHLMLMTLATGISRLNLSGCTRISEPLIG-KLLYQ 118
Query: 143 NITTLTSLICSNLISLNSTDIHLIADTFPLLEELDLAYPSKIINHTHATFSTGLEALSLA 202
N+ +T + SN+ SL + + I+D P
Sbjct: 119 NLNLVT-INFSNIFSLPANILEYISDNCP------------------------------- 146
Query: 203 LIKLRKVNLSYHGYLNGTLLSHLFKNCKFLQEVILLRCEQLTIAGVDLALLQKPTLTSLS 262
L+ +N+ G + T + + K C +L +I+ C +LT + + L +K L L
Sbjct: 147 --NLKALNIGNCGLVEDTGMVQIIKRCPYLNRLIIPNCRKLTDVSLQI-LSEKEDLIELD 203
Query: 263 ITCTVTTGLEHLTSHFIDSLLSL----KGLTSLLLTGFRISDQFLS--SIAMESLPLRRL 316
I +G E H D+L L +GL L + G F++ ++ E +R L
Sbjct: 204 I-----SGCEGF--HNADTLSRLVSRNRGLKELSMDGCTELSHFITFLNLNCELDAMRAL 256
Query: 317 VLSYCPGYTYSGISFLLSKSKRIQHLDLQYTDFLNDHCVAELSLFLGDLLSLNLGNCRLL 376
L+ P S I + K ++ L L L D + L+ L +L+LG+C +
Sbjct: 257 SLNNLPDLKDSDIELITCKFSKLNSLFLSKCIGLTDSSLLSLTKLSQSLTTLHLGHCYEI 316
Query: 377 TVSTFFALITNCPSLTEINMNRTNIQGTTIPNSLMDRLVNPQFKSLFLASAACLEDQNII 436
T L+ +C ++T I+ ++ + I S + +L P + + L CL D ++I
Sbjct: 317 TDIGVQCLLKSCKNITYIDFGGC-LRLSDIAVSAIAKL--PYLQRVGLVKCICLTDLSVI 373
Query: 437 MFAALFP-NLQQLHLSCSYNITEEGIRPLLESCRKIRHLNLT------CLSLKS 483
+ + F NL+++HLS +T + + L+ +C+ ++HL++T C L+S
Sbjct: 374 LLSGSFSRNLERVHLSYCIGLTAKSVSYLMYNCKTLKHLSVTGINSILCTELRS 427
Score = 62.0 bits (149), Expect = 4e-09
Identities = 100/424 (23%), Positives = 177/424 (41%), Gaps = 84/424 (19%)
Query: 170 FPLLEELDLAYPSKIINHTHA---TFSTGLEALSLA----------------LIKLRKVN 210
F L +L+ + K + H T +TG+ L+L+ + L +N
Sbjct: 67 FRYLRKLNCSRVRKFLTDKHLMLMTLATGISRLNLSGCTRISEPLIGKLLYQNLNLVTIN 126
Query: 211 LSYHGYLNGTLLSHLFKNCKFLQEVILLRCEQLTIAGVDLALLQKPTLTSLSITCTVTTG 270
S L +L ++ NC L+ + + C + G+ + + P L L I
Sbjct: 127 FSNIFSLPANILEYISDNCPNLKALNIGNCGLVEDTGMVQIIKRCPYLNRLIIP------ 180
Query: 271 LEHLTSHFIDSLLSLKGLTSLLLTGFRISDQFLSSIAMESLPLRRLVLSYCPGYTYSG-I 329
+ + LT + L I E L L +S C G+ + +
Sbjct: 181 -------------NCRKLTDVSL-----------QILSEKEDLIELDISGCEGFHNADTL 216
Query: 330 SFLLSKSKRIQHLDLQYTDFLNDHCVAELSLFLGDLLSLNLGNCRLLTVSTFFALITNCP 389
S L+S+++ ++ L + D C ELS F+ LNL NC L + + N P
Sbjct: 217 SRLVSRNRGLKELSM-------DGCT-ELSHFI---TFLNL-NCELDAMRALS--LNNLP 262
Query: 390 SLTEINMNRTNIQGTTIPNSLMDRLVNPQFKSLFLASAACLEDQNIIMFAALFPNLQQLH 449
L + ++I+ T S ++ SLFL+ L D +++ L +L LH
Sbjct: 263 DLKD-----SDIELITCKFSKLN--------SLFLSKCIGLTDSSLLSLTKLSQSLTTLH 309
Query: 450 LSCSYNITEEGIRPLLESCRKIRHLNL-TCLSLKSLGTN--FDLPDLEVLNLTNTE-VDD 505
L Y IT+ G++ LL+SC+ I +++ CL L + + LP L+ + L + D
Sbjct: 310 LGHCYEITDIGVQCLLKSCKNITYIDFGGCLRLSDIAVSAIAKLPYLQRVGLVKCICLTD 369
Query: 506 EALYIISNRCPALLQLV-LLRCDYITDKGVMHVVNNCTQLREINLDGCPNVQAKVVASMV 564
++ ++S L+ V L C +T K V +++ NC L+ +++ G ++ + S
Sbjct: 370 LSVILLSGSFSRNLERVHLSYCIGLTAKSVSYLMYNCKTLKHLSVTGINSILCTELRSF- 428
Query: 565 VSRP 568
SRP
Sbjct: 429 -SRP 431
Score = 50.4 bits (119), Expect = 1e-05
Identities = 64/293 (21%), Positives = 122/293 (40%), Gaps = 61/293 (20%)
Query: 326 YSGISFLLSKSKRIQHLDLQYTDFLNDHCVAELSLFLGDLLSLNLGNCRLLTVSTFFALI 385
Y ++ + I L ++++D+C +L +LN+GNC L+ + +I
Sbjct: 117 YQNLNLVTINFSNIFSLPANILEYISDNCP--------NLKALNIGNCGLVEDTGMVQII 168
Query: 386 TNCPSLTEINMNRTNIQGTTIPNSLMDRLVNPQFKSLFLASAACLEDQNIIMFAAL---- 441
CP L +RL+ P + L S L ++ ++ +
Sbjct: 169 KRCPYL--------------------NRLIIPNCRKLTDVSLQILSEKEDLIELDISGCE 208
Query: 442 -FPNLQQLHLSCSYNITEEGIRPL-LESCRKIRH----LNLTCL--SLKSLGTNFDLPDL 493
F N L S N G++ L ++ C ++ H LNL C ++++L N +LPDL
Sbjct: 209 GFHNADTLSRLVSRN---RGLKELSMDGCTELSHFITFLNLNCELDAMRALSLN-NLPDL 264
Query: 494 -----EVLNLTNTEVD-----------DEALYIISNRCPALLQLVLLRCDYITDKGVMHV 537
E++ ++++ D +L ++ +L L L C ITD GV +
Sbjct: 265 KDSDIELITCKFSKLNSLFLSKCIGLTDSSLLSLTKLSQSLTTLHLGHCYEITDIGVQCL 324
Query: 538 VNNCTQLREINLDGCPNVQAKVVASMVVSRPSLRKIHVPPNFPLSDRNRKLFS 590
+ +C + I+ GC + + + S + P L+++ + L+D + L S
Sbjct: 325 LKSCKNITYIDFGGCLRL-SDIAVSAIAKLPYLQRVGLVKCICLTDLSVILLS 376
Score = 35.0 bits (79), Expect = 0.56
Identities = 48/199 (24%), Positives = 83/199 (41%), Gaps = 20/199 (10%)
Query: 49 RKRYLKSLSVAS----KHFLSVTNRHKFCLTILYPALPVLPGLLQ--------RFTKLTS 96
R R LK LS+ HF++ N + + +L LP L +F+KL S
Sbjct: 222 RNRGLKELSMDGCTELSHFITFLNLNCELDAMRALSLNNLPDLKDSDIELITCKFSKLNS 281
Query: 97 LDLSYYYGDLDALLTQISSFPMLKLTSLNLSNQLILPANGLRAFSQNITTLTSLICSNLI 156
L LS G D+ L ++ LT+L+L + + G++ ++ +T + +
Sbjct: 282 LFLSKCIGLTDSSLLSLTKLSQ-SLTTLHLGHCYEITDIGVQCLLKSCKNITYIDFGGCL 340
Query: 157 SLNSTDIHLIADTFPLLEELDLAYPSKIINHTHATFSTGLEALSLALIKLRKVNLSYHGY 216
L+ + IA P L+ + L + + + S L +V+LSY
Sbjct: 341 RLSDIAVSAIAK-LPYLQRVGLVKCICLTDLSVILLSGSFSR------NLERVHLSYCIG 393
Query: 217 LNGTLLSHLFKNCKFLQEV 235
L +S+L NCK L+ +
Sbjct: 394 LTAKSVSYLMYNCKTLKHL 412
>FL2_HUMAN (Q9UKC9) F-box/LRR-repeat protein 2 (F-box and
leucine-rich repeat protein 2) (F-box protein FBL2/FBL3)
Length = 423
Score = 79.7 bits (195), Expect = 2e-14
Identities = 73/278 (26%), Positives = 113/278 (40%), Gaps = 44/278 (15%)
Query: 313 LRRLVLSYCPGYTYSGISFLLSKSKRIQHLDLQYTDFLNDHCVAELSLFLGDLLSLNLGN 372
LR+L L C G S + + I+HL+L + D LS F L L+L +
Sbjct: 80 LRKLSLRGCIGVGDSSLKTFAQNCRNIEHLNLNGCTKITDSTCYSLSRFCSKLKHLDLTS 139
Query: 373 CRLLTVSTFFALITNCPSLTEINMNRTNIQGTTIPNSLMDRLVNP--QFKSLFLASAACL 430
C +T S+ + C +L +N++ + I ++ LV K+L L L
Sbjct: 140 CVSITNSSLKGISEGCRNLEYLNLSWCD----QITKDGIEALVRGCRGLKALLLRGCTQL 195
Query: 431 EDQNIIMFAALFPNLQQLHLSCSYNITEEGIRPLLESCRKIRHL------NLTCLSLKSL 484
ED+ + L L+L IT+EG+ + C +++ L NLT SL +L
Sbjct: 196 EDEALKHIQNYCHELVSLNLQSCSRITDEGVVQICRGCHRLQALCLSGCSNLTDASLTAL 255
Query: 485 GTNFDLPDLEVLNLTNTE---------------------------VDDEALYIISNRCPA 517
G N P L++L + D L +S CP
Sbjct: 256 GLN--CPRLQILEAARCSHLTDAGFTLLARNCHELEKMDLEECILITDSTLIQLSIHCPK 313
Query: 518 LLQLVLLRCDYITDKGVMHVVNNC---TQLREINLDGC 552
L L L C+ ITD G++H+ N+ +LR + LD C
Sbjct: 314 LQALSLSHCELITDDGILHLSNSTCGHERLRVLELDNC 351
Score = 72.8 bits (177), Expect = 2e-12
Identities = 61/231 (26%), Positives = 106/231 (45%), Gaps = 25/231 (10%)
Query: 363 GDLLSLNLGNCRLLTVSTFFALITNCPSLTEINMNR-TNIQGTTIPNSLMDRLVNPQFKS 421
G L L+L C + S+ NC ++ +N+N T I +T + + R + + K
Sbjct: 78 GFLRKLSLRGCIGVGDSSLKTFAQNCRNIEHLNLNGCTKITDSTCYS--LSRFCS-KLKH 134
Query: 422 LFLASAACLEDQNIIMFAALFPNLQQLHLSCSYNITEEGIRPLLESCRKIRHLNLTCLSL 481
L L S + + ++ + NL+ L+LS IT++GI L+ CR ++ L L
Sbjct: 135 LDLTSCVSITNSSLKGISEGCRNLEYLNLSWCDQITKDGIEALVRGCRGLKALLLRGC-- 192
Query: 482 KSLGTNFDLPDLEVLNLTNTEVDDEALYIISNRCPALLQLVLLRCDYITDKGVMHVVNNC 541
T+++DEAL I N C L+ L L C ITD+GV+ + C
Sbjct: 193 -------------------TQLEDEALKHIQNYCHELVSLNLQSCSRITDEGVVQICRGC 233
Query: 542 TQLREINLDGCPNVQAKVVASMVVSRPSLRKIHVPPNFPLSDRNRKLFSRH 592
+L+ + L GC N+ + ++ ++ P L+ + L+D L +R+
Sbjct: 234 HRLQALCLSGCSNLTDASLTALGLNCPRLQILEAARCSHLTDAGFTLLARN 284
Score = 54.7 bits (130), Expect = 7e-07
Identities = 55/259 (21%), Positives = 111/259 (42%), Gaps = 14/259 (5%)
Query: 121 LTSLNLSNQLILPANGLRAFSQNITTLTSLICSNLISLNSTDIHLIADTFPLLEELDLAY 180
L L+L + + + L+ F+QN + L + + + + ++ L+ LDL
Sbjct: 80 LRKLSLRGCIGVGDSSLKTFAQNCRNIEHLNLNGCTKITDSTCYSLSRFCSKLKHLDLTS 139
Query: 181 PSKIINHTHATFSTGLEALSLALIKLRKVNLSYHGYLNGTLLSHLFKNCKFLQEVILLRC 240
I N + L+ +S L +NLS+ + + L + C+ L+ ++L C
Sbjct: 140 CVSITN-------SSLKGISEGCRNLEYLNLSWCDQITKDGIEALVRGCRGLKALLLRGC 192
Query: 241 EQLTIAGVDLALLQKPTLTSLSI-TCTVTTGLEHLTSHFIDSLLSLKGLTSLLLTGF-RI 298
QL + L SL++ +C+ T + L +L L+G +
Sbjct: 193 TQLEDEALKHIQNYCHELVSLNLQSCSRITD-----EGVVQICRGCHRLQALCLSGCSNL 247
Query: 299 SDQFLSSIAMESLPLRRLVLSYCPGYTYSGISFLLSKSKRIQHLDLQYTDFLNDHCVAEL 358
+D L+++ + L+ L + C T +G + L ++ +DL+ + D + +L
Sbjct: 248 TDASLTALGLNCPRLQILEAARCSHLTDAGFTLLARNCHELEKMDLEECILITDSTLIQL 307
Query: 359 SLFLGDLLSLNLGNCRLLT 377
S+ L +L+L +C L+T
Sbjct: 308 SIHCPKLQALSLSHCELIT 326
Score = 54.3 bits (129), Expect = 9e-07
Identities = 61/258 (23%), Positives = 113/258 (43%), Gaps = 16/258 (6%)
Query: 147 LTSLICSNLISLNSTDIHLIADTFPLLEELDLAYPSKIINHTHATFSTGLEALSLALIKL 206
L L I + + + A +E L+L +KI + T +LS KL
Sbjct: 80 LRKLSLRGCIGVGDSSLKTFAQNCRNIEHLNLNGCTKITDST-------CYSLSRFCSKL 132
Query: 207 RKVNLSYHGYLNGTLLSHLFKNCKFLQEVILLRCEQLTIAGVDLALLQKPTLTSLSIT-C 265
+ ++L+ + + L + + C+ L+ + L C+Q+T G++ + L +L + C
Sbjct: 133 KHLDLTSCVSITNSSLKGISEGCRNLEYLNLSWCDQITKDGIEALVRGCRGLKALLLRGC 192
Query: 266 TVTT--GLEHLTSHFIDSLLSLKGLTSLLLTGFRISDQFLSSIAMESLPLRRLVLSYCPG 323
T L+H+ ++ L+SL L + RI+D+ + I L+ L LS C
Sbjct: 193 TQLEDEALKHI-QNYCHELVSLN-----LQSCSRITDEGVVQICRGCHRLQALCLSGCSN 246
Query: 324 YTYSGISFLLSKSKRIQHLDLQYTDFLNDHCVAELSLFLGDLLSLNLGNCRLLTVSTFFA 383
T + ++ L R+Q L+ L D L+ +L ++L C L+T ST
Sbjct: 247 LTDASLTALGLNCPRLQILEAARCSHLTDAGFTLLARNCHELEKMDLEECILITDSTLIQ 306
Query: 384 LITNCPSLTEINMNRTNI 401
L +CP L ++++ +
Sbjct: 307 LSIHCPKLQALSLSHCEL 324
Score = 51.6 bits (122), Expect = 6e-06
Identities = 84/338 (24%), Positives = 137/338 (39%), Gaps = 42/338 (12%)
Query: 206 LRKVNLSYHGYLNGTLLSHLFKNCKFLQEVILLRCEQLTIAGVDLALLQKPTLTSLSITC 265
LRK++L + + L +NC+ ++ + L C ++T + T SLS C
Sbjct: 80 LRKLSLRGCIGVGDSSLKTFAQNCRNIEHLNLNGCTKITDS----------TCYSLSRFC 129
Query: 266 TVTTGLEHLTSHFIDSLLSLKGLT----SLLLTGFRISDQF----LSSIAMESLPLRRLV 317
+ L+ LTS + SLKG++ +L DQ + ++ L+ L+
Sbjct: 130 SKLKHLD-LTSCVSITNSSLKGISEGCRNLEYLNLSWCDQITKDGIEALVRGCRGLKALL 188
Query: 318 LSYCPGYTYSGISFLLSKSKRIQHLDLQYTDFLNDHCVAELSLFLGDLLSLNLGNCRLLT 377
L C + + + + L+LQ + D V ++ L +L L C LT
Sbjct: 189 LRGCTQLEDEALKHIQNYCHELVSLNLQSCSRITDEGVVQICRGCHRLQALCLSGCSNLT 248
Query: 378 VSTFFALITNCPSLTEINMNRTNIQGTTIPNSLMDRLVNPQFKSLFLASAACLEDQNIIM 437
++ AL NCP L + R + T +L+ R + + + + L + D +I
Sbjct: 249 DASLTALGLNCPRLQILEAARCS-HLTDAGFTLLARNCH-ELEKMDLEECILITDSTLIQ 306
Query: 438 FAALFPNLQQLHLSCSYNITEEGIRPLLESCRKIRHLNLTCLSLKSLGTNFDLPDLEVLN 497
+ P LQ L LS IT++GI L N TC + L VL
Sbjct: 307 LSIHCPKLQALSLSHCELITDDGILHL---------SNSTCGHER----------LRVLE 347
Query: 498 LTN-TEVDDEALYIISNRCPALLQLVLLRCDYITDKGV 534
L N + D AL + N C L +L L C +T G+
Sbjct: 348 LDNCLLITDVALEHLEN-CRGLERLELYDCQQVTRAGI 384
Score = 31.6 bits (70), Expect = 6.2
Identities = 44/159 (27%), Positives = 63/159 (38%), Gaps = 23/159 (14%)
Query: 120 KLTSLNLSNQLILPANGLRAFSQNITTLTSLICSNLISLNSTDIHLIADTFPLLEELDLA 179
+L +L LS L L A N L L + L L+A LE++DL
Sbjct: 235 RLQALCLSGCSNLTDASLTALGLNCPRLQILEAARCSHLTDAGFTLLARNCHELEKMDLE 294
Query: 180 YPSKIINHTHATFSTG---LEALSLA---LI----------------KLRKVNLSYHGYL 217
I + T S L+ALSL+ LI +LR + L +
Sbjct: 295 ECILITDSTLIQLSIHCPKLQALSLSHCELITDDGILHLSNSTCGHERLRVLELDNCLLI 354
Query: 218 NGTLLSHLFKNCKFLQEVILLRCEQLTIAGVDLALLQKP 256
L HL +NC+ L+ + L C+Q+T AG+ Q P
Sbjct: 355 TDVALEHL-ENCRGLERLELYDCQQVTRAGIKRMRAQLP 392
>FL2_MOUSE (Q8BH16) F-box/LRR-repeat protein 2 (F-box and
leucine-rich repeat protein 2)
Length = 423
Score = 76.6 bits (187), Expect = 2e-13
Identities = 72/278 (25%), Positives = 114/278 (40%), Gaps = 44/278 (15%)
Query: 313 LRRLVLSYCPGYTYSGISFLLSKSKRIQHLDLQYTDFLNDHCVAELSLFLGDLLSLNLGN 372
LR+L L C G S + + I+HL+L + D LS F L L+L +
Sbjct: 80 LRKLSLRGCIGVGDSSLKTFAQNCRNIEHLNLNGCTKITDSTCYSLSRFCSKLKHLDLTS 139
Query: 373 CRLLTVSTFFALITNCPSLTEINMNRTNIQGTTIPNSLMDRLVNP--QFKSLFLASAACL 430
C +T S+ + C +L +N++ + I ++ LV K+L L L
Sbjct: 140 CVSVTNSSLKGISEGCRNLEYLNLSWCD----QITKEGIEALVRGCRGLKALLLRGCTQL 195
Query: 431 EDQNIIMFAALFPNLQQLHLSCSYNITEEGIRPLLESCRKIRHL------NLTCLSLKSL 484
ED+ + L L+L IT++G+ + C +++ L NLT SL +L
Sbjct: 196 EDEALKHIQNHCHELVSLNLQSCSRITDDGVVQICRGCHRLQALCLSGCSNLTDASLTAL 255
Query: 485 GTNFDLPDLEVLNLTNTE---------------------------VDDEALYIISNRCPA 517
G N P L+VL + D L +S CP
Sbjct: 256 GLN--CPRLQVLEAARCSHLTDAGFTLLARNCHELEKMDLEECVLITDSTLVQLSIHCPK 313
Query: 518 LLQLVLLRCDYITDKGVMHVVNNC---TQLREINLDGC 552
L L L C+ ITD+G++H+ ++ +LR + LD C
Sbjct: 314 LQALSLSHCELITDEGILHLSSSTCGHERLRVLELDNC 351
Score = 73.9 bits (180), Expect = 1e-12
Identities = 62/231 (26%), Positives = 105/231 (44%), Gaps = 25/231 (10%)
Query: 363 GDLLSLNLGNCRLLTVSTFFALITNCPSLTEINMNR-TNIQGTTIPNSLMDRLVNPQFKS 421
G L L+L C + S+ NC ++ +N+N T I +T + + R + + K
Sbjct: 78 GFLRKLSLRGCIGVGDSSLKTFAQNCRNIEHLNLNGCTKITDSTCYS--LSRFCS-KLKH 134
Query: 422 LFLASAACLEDQNIIMFAALFPNLQQLHLSCSYNITEEGIRPLLESCRKIRHLNLTCLSL 481
L L S + + ++ + NL+ L+LS IT+EGI L+ CR ++ L L
Sbjct: 135 LDLTSCVSVTNSSLKGISEGCRNLEYLNLSWCDQITKEGIEALVRGCRGLKALLLRGC-- 192
Query: 482 KSLGTNFDLPDLEVLNLTNTEVDDEALYIISNRCPALLQLVLLRCDYITDKGVMHVVNNC 541
T+++DEAL I N C L+ L L C ITD GV+ + C
Sbjct: 193 -------------------TQLEDEALKHIQNHCHELVSLNLQSCSRITDDGVVQICRGC 233
Query: 542 TQLREINLDGCPNVQAKVVASMVVSRPSLRKIHVPPNFPLSDRNRKLFSRH 592
+L+ + L GC N+ + ++ ++ P L+ + L+D L +R+
Sbjct: 234 HRLQALCLSGCSNLTDASLTALGLNCPRLQVLEAARCSHLTDAGFTLLARN 284
Score = 55.1 bits (131), Expect = 5e-07
Identities = 77/333 (23%), Positives = 139/333 (41%), Gaps = 42/333 (12%)
Query: 147 LTSLICSNLISLNSTDIHLIADTFPLLEELDLAYPSKIINHTHATFSTGLEALSLALIKL 206
L L I + + + A +E L+L +KI + T +LS KL
Sbjct: 80 LRKLSLRGCIGVGDSSLKTFAQNCRNIEHLNLNGCTKITDST-------CYSLSRFCSKL 132
Query: 207 RKVNLSYHGYLNGTLLSHLFKNCKFLQEVILLRCEQLTIAGVDLALLQKPTLTSLSIT-C 265
+ ++L+ + + L + + C+ L+ + L C+Q+T G++ + L +L + C
Sbjct: 133 KHLDLTSCVSVTNSSLKGISEGCRNLEYLNLSWCDQITKEGIEALVRGCRGLKALLLRGC 192
Query: 266 TVTT--GLEHLTSHFIDSLLSLKGLTSLLLTGFRISDQFLSSIAMESLPLRRLVLSYCPG 323
T L+H+ +H L+SL L + RI+D + I L+ L LS C
Sbjct: 193 TQLEDEALKHIQNH-CHELVSLN-----LQSCSRITDDGVVQICRGCHRLQALCLSGCSN 246
Query: 324 YTYSGISFLLSKSKRIQHLDLQYTDFLNDHCVAELSLFLGDLLSLNLGNCRLLTVSTFFA 383
T + ++ L R+Q L+ L D L+ +L ++L C L+T ST
Sbjct: 247 LTDASLTALGLNCPRLQVLEAARCSHLTDAGFTLLARNCHELEKMDLEECVLITDSTLVQ 306
Query: 384 LITNCPSLTEINMNRTNIQGTTIPNSLMDRLVNPQFKSLFLASAACLEDQNIIMFAALFP 443
L +CP L ++++ + + D + L L+S+ C ++
Sbjct: 307 LSIHCPKLQALSLSHCEL--------ITDEGI------LHLSSSTCGHER---------- 342
Query: 444 NLQQLHLSCSYNITEEGIRPLLESCRKIRHLNL 476
L+ L L +T+ + LE+CR + L L
Sbjct: 343 -LRVLELDNCLLVTDASLEH-LENCRGLERLEL 373
Score = 55.1 bits (131), Expect = 5e-07
Identities = 54/259 (20%), Positives = 111/259 (42%), Gaps = 14/259 (5%)
Query: 121 LTSLNLSNQLILPANGLRAFSQNITTLTSLICSNLISLNSTDIHLIADTFPLLEELDLAY 180
L L+L + + + L+ F+QN + L + + + + ++ L+ LDL
Sbjct: 80 LRKLSLRGCIGVGDSSLKTFAQNCRNIEHLNLNGCTKITDSTCYSLSRFCSKLKHLDLTS 139
Query: 181 PSKIINHTHATFSTGLEALSLALIKLRKVNLSYHGYLNGTLLSHLFKNCKFLQEVILLRC 240
+ N + L+ +S L +NLS+ + + L + C+ L+ ++L C
Sbjct: 140 CVSVTN-------SSLKGISEGCRNLEYLNLSWCDQITKEGIEALVRGCRGLKALLLRGC 192
Query: 241 EQLTIAGVDLALLQKPTLTSLSI-TCTVTTGLEHLTSHFIDSLLSLKGLTSLLLTG-FRI 298
QL + L SL++ +C+ T + L +L L+G +
Sbjct: 193 TQLEDEALKHIQNHCHELVSLNLQSCSRIT-----DDGVVQICRGCHRLQALCLSGCSNL 247
Query: 299 SDQFLSSIAMESLPLRRLVLSYCPGYTYSGISFLLSKSKRIQHLDLQYTDFLNDHCVAEL 358
+D L+++ + L+ L + C T +G + L ++ +DL+ + D + +L
Sbjct: 248 TDASLTALGLNCPRLQVLEAARCSHLTDAGFTLLARNCHELEKMDLEECVLITDSTLVQL 307
Query: 359 SLFLGDLLSLNLGNCRLLT 377
S+ L +L+L +C L+T
Sbjct: 308 SIHCPKLQALSLSHCELIT 326
Score = 52.8 bits (125), Expect = 3e-06
Identities = 80/337 (23%), Positives = 133/337 (38%), Gaps = 40/337 (11%)
Query: 206 LRKVNLSYHGYLNGTLLSHLFKNCKFLQEVILLRCEQLTIAGVDLALLQKPTLTSLSITC 265
LRK++L + + L +NC+ ++ + L C ++T + T SLS C
Sbjct: 80 LRKLSLRGCIGVGDSSLKTFAQNCRNIEHLNLNGCTKITDS----------TCYSLSRFC 129
Query: 266 TVTTGLEHLTSHFIDSLLSLKGLTSLLLTGFRISDQFLSSIAMESLP--------LRRLV 317
+ L+ LTS + SLKG++ ++ + I E + L+ L+
Sbjct: 130 SKLKHLD-LTSCVSVTNSSLKGISEGCRNLEYLNLSWCDQITKEGIEALVRGCRGLKALL 188
Query: 318 LSYCPGYTYSGISFLLSKSKRIQHLDLQYTDFLNDHCVAELSLFLGDLLSLNLGNCRLLT 377
L C + + + + L+LQ + D V ++ L +L L C LT
Sbjct: 189 LRGCTQLEDEALKHIQNHCHELVSLNLQSCSRITDDGVVQICRGCHRLQALCLSGCSNLT 248
Query: 378 VSTFFALITNCPSLTEINMNRTNIQGTTIPNSLMDRLVNPQFKSLFLASAACLEDQNIIM 437
++ AL NCP L + R + T +L+ R + + + + L + D ++
Sbjct: 249 DASLTALGLNCPRLQVLEAARCS-HLTDAGFTLLARNCH-ELEKMDLEECVLITDSTLVQ 306
Query: 438 FAALFPNLQQLHLSCSYNITEEGIRPLLESCRKIRHLNLTCLSLKSLGTNFDLPDLEVLN 497
+ P LQ L LS IT+EGI L S TC + L VL
Sbjct: 307 LSIHCPKLQALSLSHCELITDEGILHLSSS---------TCGHER----------LRVLE 347
Query: 498 LTNTEVDDEALYIISNRCPALLQLVLLRCDYITDKGV 534
L N + +A C L +L L C +T G+
Sbjct: 348 LDNCLLVTDASLEHLENCRGLERLELYDCQQVTRAGI 384
Score = 31.2 bits (69), Expect = 8.1
Identities = 44/159 (27%), Positives = 63/159 (38%), Gaps = 23/159 (14%)
Query: 120 KLTSLNLSNQLILPANGLRAFSQNITTLTSLICSNLISLNSTDIHLIADTFPLLEELDLA 179
+L +L LS L L A N L L + L L+A LE++DL
Sbjct: 235 RLQALCLSGCSNLTDASLTALGLNCPRLQVLEAARCSHLTDAGFTLLARNCHELEKMDLE 294
Query: 180 YPSKIINHTHATFSTG---LEALSLA---LI----------------KLRKVNLSYHGYL 217
I + T S L+ALSL+ LI +LR + L +
Sbjct: 295 ECVLITDSTLVQLSIHCPKLQALSLSHCELITDEGILHLSSSTCGHERLRVLELDNCLLV 354
Query: 218 NGTLLSHLFKNCKFLQEVILLRCEQLTIAGVDLALLQKP 256
L HL +NC+ L+ + L C+Q+T AG+ Q P
Sbjct: 355 TDASLEHL-ENCRGLERLELYDCQQVTRAGIKRMRAQLP 392
>FXL4_HUMAN (Q9UKA2) F-box/LRR-repeat protein 4 (F-box and
leucine-rich repeat protein 4) (F-box protein FBL4/FBL5)
Length = 621
Score = 75.1 bits (183), Expect = 5e-13
Identities = 84/331 (25%), Positives = 143/331 (42%), Gaps = 25/331 (7%)
Query: 253 LQKPTLTSLSITCTVTTGLEHLTSHFIDSLLSLKGLTSLLLTGFRISDQFLSSIAMESLP 312
L P L L+ TC + L+ H D L + +L ++ D L +
Sbjct: 295 LTLPDLCRLAQTCKL------LSQHCCDPLQYIH--LNLQPYWAKLDDTSLEFLQSRCTL 346
Query: 313 LRRLVLSYCPGYTYSGIS----FLLSKSKRIQHLDLQYTDFLNDHCVAELSLFLGDLLSL 368
++ L LS+ + ++ FL + L+L + FLN+ C+ +S +L +L
Sbjct: 347 VQWLNLSWTGNRGFISVAGFSRFLKVCGSELVRLELSCSHFLNETCLEVISEMCPNLQAL 406
Query: 369 NLGNCRLLTVSTFFALITNCPSLTEINMNRTNIQGTTIPNSLMDRLVNPQFKSLFLASAA 428
NL +C L F + C SL + + RT ++ T + + L + + L L S
Sbjct: 407 NLSSCDKLPPQAFNHIAKLC-SLKRLVLYRTKVEQTALLSILN---FCSELQHLSLGSCV 462
Query: 429 CLEDQNII--MFAALFPNLQQLHLSCSYNITEEGIRPLLESCRKIRHLNL-TCLSLKSLG 485
+ED ++I M A L+ L L NITE GI L C + L+L C +L+S
Sbjct: 463 MIEDYDVIASMIGAKCKKLRTLDLWRCKNITENGIAELASGCPLLEELDLGWCPTLQSST 522
Query: 486 TNF-----DLPDLEVLNLT-NTEVDDEALYIISNRCPALLQLVLLRCDYITDKGVMHVVN 539
F LP+L+ L LT N V D + ++ C L QL +L ++ + ++
Sbjct: 523 GCFTRLAHQLPNLQKLFLTANRSVCDTDIDELACNCTRLQQLDILGTRMVSPASLRKLLE 582
Query: 540 NCTQLREINLDGCPNVQAKVVASMVVSRPSL 570
+C L +++ C + + V + S P +
Sbjct: 583 SCKDLSLLDVSFCSQIDNRAVLELNASFPKV 613
Score = 52.8 bits (125), Expect = 3e-06
Identities = 46/172 (26%), Positives = 72/172 (41%), Gaps = 33/172 (19%)
Query: 445 LQQLHLSCSYNITEEGIRPLLESCRKIRHLNLT-CLSLKSLGTNF--DLPDLEVLNLTNT 501
L +L LSCS+ + E + + E C ++ LNL+ C L N L L+ L L T
Sbjct: 377 LVRLELSCSHFLNETCLEVISEMCPNLQALNLSSCDKLPPQAFNHIAKLCSLKRLVLYRT 436
Query: 502 EVDDEALYIISN----------------------------RCPALLQLVLLRCDYITDKG 533
+V+ AL I N +C L L L RC IT+ G
Sbjct: 437 KVEQTALLSILNFCSELQHLSLGSCVMIEDYDVIASMIGAKCKKLRTLDLWRCKNITENG 496
Query: 534 VMHVVNNCTQLREINLDGCPNVQAKV--VASMVVSRPSLRKIHVPPNFPLSD 583
+ + + C L E++L CP +Q+ + P+L+K+ + N + D
Sbjct: 497 IAELASGCPLLEELDLGWCPTLQSSTGCFTRLAHQLPNLQKLFLTANRSVCD 548
Score = 45.1 bits (105), Expect = 5e-04
Identities = 78/334 (23%), Positives = 136/334 (40%), Gaps = 29/334 (8%)
Query: 128 NQLILP-----ANGLRAFSQNITTLTSLICSNL----ISLNSTDIHLIADTFPLLEELDL 178
N L LP A + SQ+ I NL L+ T + + L++ L+L
Sbjct: 293 NHLTLPDLCRLAQTCKLLSQHCCDPLQYIHLNLQPYWAKLDDTSLEFLQSRCTLVQWLNL 352
Query: 179 AYPSKIINHTHATFSTGLEALSLALIKLRKVNLSYHGYLNGTLLSHLFKNCKFLQEVILL 238
++ + A FS L+ L++L LS +LN T L + + C LQ + L
Sbjct: 353 SWTGNRGFISVAGFSRFLKVCGSELVRLE---LSCSHFLNETCLEVISEMCPNLQALNLS 409
Query: 239 RCEQLTIAGVD----LALLQKPTLTSLSITCTVTTGLEHLTSHFIDSLLSLKGLTSLLLT 294
C++L + L L++ L + T + +F L L + +++
Sbjct: 410 SCDKLPPQAFNHIAKLCSLKRLVLYRTKVEQTALLSI----LNFCSELQHLSLGSCVMIE 465
Query: 295 GFRISDQFLSSIAMESLPLRRLVLSYCPGYTYSGISFLLSKSKRIQHLDLQYTDFLNDH- 353
+ D S I + LR L L C T +GI+ L S ++ LDL + L
Sbjct: 466 DY---DVIASMIGAKCKKLRTLDLWRCKNITENGIAELASGCPLLEELDLGWCPTLQSST 522
Query: 354 -CVAELSLFLGDLLSLNLGNCRLLTVSTFFALITNCPSLTEINMNRTNIQGTTIPNSLMD 412
C L+ L +L L L R + + L NC L ++++ T + P SL
Sbjct: 523 GCFTRLAHQLPNLQKLFLTANRSVCDTDIDELACNCTRLQQLDILGTRM---VSPASLRK 579
Query: 413 RLVNPQFKSLF-LASAACLEDQNIIMFAALFPNL 445
L + + SL ++ + ++++ ++ A FP +
Sbjct: 580 LLESCKDLSLLDVSFCSQIDNRAVLELNASFPKV 613
>YKK7_CAEEL (P34284) Hypothetical F-box/LRR-repeat protein C02F5.7
in chromosome III
Length = 461
Score = 68.9 bits (167), Expect = 3e-11
Identities = 68/307 (22%), Positives = 137/307 (44%), Gaps = 20/307 (6%)
Query: 297 RISDQFLSSIAMESLPLRRLVLSYCPGYTYSGISFLLSKSKRIQHLDLQYTDFLNDHCVA 356
R++D ++ L L L C T + ++ + +L++ + D + D V
Sbjct: 161 RVTDASCENLGRYCHKLNYLNLENCSSITDRAMKYIGDGCPNLSYLNISWCDAIQDRGVQ 220
Query: 357 ELSLFLGDLLSLNLGNCRLLTVSTFFALITNCPSLTEINMNRTNIQGTTIPNSLMDRLVN 416
+ L +L L C LT + F ++ + ++ ++N+ +Q + + + + N
Sbjct: 221 IILSNCKSLDTLILRGCEGLTENVFGSVEAHMGAIKKLNL----LQCFQLTDITVQNIAN 276
Query: 417 PQFKSLFLASAAC--LEDQNIIMFAALFPNLQQLHLSCSYNITEEGIRPLLESCRKIRHL 474
+L + C + D++++ NL+ L LS + + G PL CR++ L
Sbjct: 277 GATALEYLCMSNCNQISDRSLVSLGQHSHNLKVLELSGCTLLGDNGFIPLARGCRQLERL 336
Query: 475 NLTCLSLKSLGTNFDLPD----LEVLNLTNTE-VDDEALYIISNRCPALLQLVLL-RCDY 528
++ SL S T L + L L+L++ E + DE++ ++++ L ++ L C
Sbjct: 337 DMEDCSLISDHTINSLANNCTALRELSLSHCELITDESIQNLASKHRETLNVLELDNCPQ 396
Query: 529 ITDKGVMHVVNNCTQLREINLDGCPNVQAKVVASMVVSRPSLRKIH------VPPNFPLS 582
+TD + H+ +C L+ I+L C NV + + RP++ +IH PP +
Sbjct: 397 LTDSTLSHL-RHCKALKRIDLYDCQNVSKEAIVRFQHHRPNI-EIHAYFAPVTPPTDQVV 454
Query: 583 DRNRKLF 589
+R LF
Sbjct: 455 NRGGMLF 461
Score = 63.9 bits (154), Expect = 1e-09
Identities = 43/146 (29%), Positives = 71/146 (48%), Gaps = 9/146 (6%)
Query: 445 LQQLHLSCSYNITEEGIRPLLESCRKIRHLNL------TCLSLKSLGTNFDLPDLEVLNL 498
L++L L N+ + +R C + HL+L T S ++LG L LNL
Sbjct: 125 LKELSLKGCENVHDSALRTFTSRCPNLEHLSLYRCKRVTDASCENLGRYCH--KLNYLNL 182
Query: 499 TN-TEVDDEALYIISNRCPALLQLVLLRCDYITDKGVMHVVNNCTQLREINLDGCPNVQA 557
N + + D A+ I + CP L L + CD I D+GV +++NC L + L GC +
Sbjct: 183 ENCSSITDRAMKYIGDGCPNLSYLNISWCDAIQDRGVQIILSNCKSLDTLILRGCEGLTE 242
Query: 558 KVVASMVVSRPSLRKIHVPPNFPLSD 583
V S+ +++K+++ F L+D
Sbjct: 243 NVFGSVEAHMGAIKKLNLLQCFQLTD 268
Score = 60.5 bits (145), Expect = 1e-08
Identities = 59/253 (23%), Positives = 106/253 (41%), Gaps = 23/253 (9%)
Query: 313 LRRLVLSYCPGYTYSGISFLLSKSKRIQHLDLQYTDFLNDHCVAELSLFLGDLLSLNLGN 372
L+ L L C S + S+ ++HL L + D L + L LNL N
Sbjct: 125 LKELSLKGCENVHDSALRTFTSRCPNLEHLSLYRCKRVTDASCENLGRYCHKLNYLNLEN 184
Query: 373 CRLLTVSTFFALITNCPSLTEINMNRTNIQGTTIPNSLMDRLVN------PQFKSLFLAS 426
C +T + CP+L+ +N++ + ++ DR V +L L
Sbjct: 185 CSSITDRAMKYIGDGCPNLSYLNISWCD--------AIQDRGVQIILSNCKSLDTLILRG 236
Query: 427 AACLEDQNIIMFAALFPNLQQLHLSCSYNITEEGIRPLLESCRKIRHL------NLTCLS 480
L + A +++L+L + +T+ ++ + + +L ++ S
Sbjct: 237 CEGLTENVFGSVEAHMGAIKKLNLLQCFQLTDITVQNIANGATALEYLCMSNCNQISDRS 296
Query: 481 LKSLGTNFDLPDLEVLNLTN-TEVDDEALYIISNRCPALLQLVLLRCDYITDKGVMHVVN 539
L SLG + +L+VL L+ T + D ++ C L +L + C I+D + + N
Sbjct: 297 LVSLGQHSH--NLKVLELSGCTLLGDNGFIPLARGCRQLERLDMEDCSLISDHTINSLAN 354
Query: 540 NCTQLREINLDGC 552
NCT LRE++L C
Sbjct: 355 NCTALRELSLSHC 367
Score = 50.1 bits (118), Expect = 2e-05
Identities = 45/199 (22%), Positives = 87/199 (43%), Gaps = 7/199 (3%)
Query: 205 KLRKVNLSYHGYLNGTLLSHLFKNCKFLQEVILLRCEQLTIAGVDLALLQKPTLTSLSIT 264
KL +NL + + ++ C L + + C+ + GV + L +L +L
Sbjct: 176 KLNYLNLENCSSITDRAMKYIGDGCPNLSYLNISWCDAIQDRGVQIILSNCKSLDTL--- 232
Query: 265 CTVTTGLEHLTSHFIDSLLSLKGLTSLL--LTGFRISDQFLSSIAMESLPLRRLVLSYCP 322
+ G E LT + S+ + G L L F+++D + +IA + L L +S C
Sbjct: 233 --ILRGCEGLTENVFGSVEAHMGAIKKLNLLQCFQLTDITVQNIANGATALEYLCMSNCN 290
Query: 323 GYTYSGISFLLSKSKRIQHLDLQYTDFLNDHCVAELSLFLGDLLSLNLGNCRLLTVSTFF 382
+ + L S ++ L+L L D+ L+ L L++ +C L++ T
Sbjct: 291 QISDRSLVSLGQHSHNLKVLELSGCTLLGDNGFIPLARGCRQLERLDMEDCSLISDHTIN 350
Query: 383 ALITNCPSLTEINMNRTNI 401
+L NC +L E++++ +
Sbjct: 351 SLANNCTALRELSLSHCEL 369
Score = 49.3 bits (116), Expect = 3e-05
Identities = 54/217 (24%), Positives = 90/217 (40%), Gaps = 41/217 (18%)
Query: 206 LRKVNLSYHGYLNGTLLSHLFKNCKFLQEVILLRCEQLT---IAGVD--------LALLQ 254
L +N+S+ + + + NCK L +IL CE LT V+ L LLQ
Sbjct: 203 LSYLNISWCDAIQDRGVQIILSNCKSLDTLILRGCEGLTENVFGSVEAHMGAIKKLNLLQ 262
Query: 255 KPTLTSLSIT--CTVTTGLEHLTSHFIDSLLSLKGLTSLLLTGFRISDQFLSSIAMESLP 312
LT +++ T LE+L + +ISD+ L S+ S
Sbjct: 263 CFQLTDITVQNIANGATALEYLCMSNCN----------------QISDRSLVSLGQHSHN 306
Query: 313 LRRLVLSYCPGYTYSGISFLLSKSKRIQHLDLQYTDFLNDHCVAELSLFLGDLLSLNLGN 372
L+ L LS C +G L ++++ LD++ ++DH + L+ L L+L +
Sbjct: 307 LKVLELSGCTLLGDNGFIPLARGCRQLERLDMEDCSLISDHTINSLANNCTALRELSLSH 366
Query: 373 CRLLTVSTFFAL------------ITNCPSLTEINMN 397
C L+T + L + NCP LT+ ++
Sbjct: 367 CELITDESIQNLASKHRETLNVLELDNCPQLTDSTLS 403
Score = 44.3 bits (103), Expect = 0.001
Identities = 27/93 (29%), Positives = 47/93 (50%), Gaps = 1/93 (1%)
Query: 493 LEVLNLTNTE-VDDEALYIISNRCPALLQLVLLRCDYITDKGVMHVVNNCTQLREINLDG 551
L+ L+L E V D AL ++RCP L L L RC +TD ++ C +L +NL+
Sbjct: 125 LKELSLKGCENVHDSALRTFTSRCPNLEHLSLYRCKRVTDASCENLGRYCHKLNYLNLEN 184
Query: 552 CPNVQAKVVASMVVSRPSLRKIHVPPNFPLSDR 584
C ++ + + + P+L +++ + DR
Sbjct: 185 CSSITDRAMKYIGDGCPNLSYLNISWCDAIQDR 217
>FXL7_HUMAN (Q9UJT9) F-box/LRR-repeat protein 7 (F-box and
leucine-rich repeat protein 7) (F-box protein FBL6/FBL7)
Length = 491
Score = 67.0 bits (162), Expect = 1e-10
Identities = 56/236 (23%), Positives = 110/236 (45%), Gaps = 13/236 (5%)
Query: 350 LNDHCVAELSLFLGDLLSLNLGNCRLLTVSTFFALITNCPSLTEINMNR----TNIQGTT 405
L D + ++ +L L + C ++ F +++ CP+L ++++ T I T
Sbjct: 199 LTDRGLYTIAQCCPELRRLEVSGCYNISNEAVFDVVSLCPNLEHLDVSGCSKVTCISLTR 258
Query: 406 IPNSLMDRLVNPQFKSLFLASAAC--LEDQNIIMFAALFPNLQQLHLSCSYNITEEGIRP 463
+ + L Q +L C LED+ + AA L L+L +T+EG+R
Sbjct: 259 EASIKLSPLHGKQISIRYLDMTDCFVLEDEGLHTIAAHCTQLTHLYLRRCVRLTDEGLRY 318
Query: 464 LLESCRKIRHLNLT-CLSLKSLGTNFDLPDLE----VLNLTNT-EVDDEALYIISNRCPA 517
L+ C I+ L+++ C + G ++ LE L++ + V D + ++ C
Sbjct: 319 LVIYCASIKELSVSDCRFVSDFGLR-EIAKLESRLRYLSIAHCGRVTDVGIRYVAKYCSK 377
Query: 518 LLQLVLLRCDYITDKGVMHVVNNCTQLREINLDGCPNVQAKVVASMVVSRPSLRKI 573
L L C+ ITD GV ++ NCT+L+ +++ CP V + + ++ +L+++
Sbjct: 378 LRYLNARGCEGITDHGVEYLAKNCTKLKSLDIGKCPLVSDTGLECLALNCFNLKRL 433
Score = 57.4 bits (137), Expect = 1e-07
Identities = 59/289 (20%), Positives = 119/289 (40%), Gaps = 35/289 (12%)
Query: 297 RISDQFLSSIAMESLPLRRLVLSYCPGYTYSGISFLLSKSKRIQHLDLQYTD-----FLN 351
R++D+ L +IA LRRL +S C + + ++S ++HLD+ L
Sbjct: 198 RLTDRGLYTIAQCCPELRRLEVSGCYNISNEAVFDVVSLCPNLEHLDVSGCSKVTCISLT 257
Query: 352 DHCVAELSLFLGDLLS---LNLGNCRLLTVSTFFALITNCPSLTEINMNRTNIQGTTIPN 408
+LS G +S L++ +C +L + +C LT + + R + +
Sbjct: 258 REASIKLSPLHGKQISIRYLDMTDCFVLEDEGLHTIAAHCTQLTHLYLRRC----VRLTD 313
Query: 409 SLMDRLVN--PQFKSLFLASAACLEDQNIIMFAALFPNLQQLHLSCSYNITEEGIRPLLE 466
+ LV K L ++ + D + A L L+ L ++ +T+ GIR + +
Sbjct: 314 EGLRYLVIYCASIKELSVSDCRFVSDFGLREIAKLESRLRYLSIAHCGRVTDVGIRYVAK 373
Query: 467 SCRKIRHLNLTCLSLKSLGTNFDLPDLEVLNLTNTEVDDEALYIISNRCPALLQLVLLRC 526
C K+R+LN + D + ++ C L L + +C
Sbjct: 374 YCSKLRYLNARGCE---------------------GITDHGVEYLAKNCTKLKSLDIGKC 412
Query: 527 DYITDKGVMHVVNNCTQLREINLDGCPNVQAKVVASMVVSRPSLRKIHV 575
++D G+ + NC L+ ++L C ++ + + + + L+ ++V
Sbjct: 413 PLVSDTGLECLALNCFNLKRLSLKSCESITGQGLQIVAANCFDLQTLNV 461
Score = 56.2 bits (134), Expect = 2e-07
Identities = 68/283 (24%), Positives = 122/283 (43%), Gaps = 12/283 (4%)
Query: 119 LKLTSLNLSNQLILPANGLRAFSQNITTLTSLICSNLISLNSTDIHLIADTFPLLEELDL 178
L L ++ +S L GL +Q L L S ++++ + + P LE LD+
Sbjct: 186 LMLETVTVSGCRRLTDRGLYTIAQCCPELRRLEVSGCYNISNEAVFDVVSLCPNLEHLDV 245
Query: 179 AYPSKI--INHTHATFSTGLEALSLALIKLRKVNLSYHGYLNGTLLSHLFKNCKFLQEVI 236
+ SK+ I+ T S L L I +R ++++ L L + +C L +
Sbjct: 246 SGCSKVTCISLTREA-SIKLSPLHGKQISIRYLDMTDCFVLEDEGLHTIAAHCTQLTHLY 304
Query: 237 LLRCEQLTIAGVDLALLQKPTLTSLSIT-CTVTT--GLEHLTSHFIDSLLSLKGLTSLLL 293
L RC +LT G+ ++ ++ LS++ C + GL + L S S+
Sbjct: 305 LRRCVRLTDEGLRYLVIYCASIKELSVSDCRFVSDFGLREIAK-----LESRLRYLSIAH 359
Query: 294 TGFRISDQFLSSIAMESLPLRRLVLSYCPGYTYSGISFLLSKSKRIQHLDLQYTDFLNDH 353
G R++D + +A LR L C G T G+ +L +++ LD+ ++D
Sbjct: 360 CG-RVTDVGIRYVAKYCSKLRYLNARGCEGITDHGVEYLAKNCTKLKSLDIGKCPLVSDT 418
Query: 354 CVAELSLFLGDLLSLNLGNCRLLTVSTFFALITNCPSLTEINM 396
+ L+L +L L+L +C +T + NC L +N+
Sbjct: 419 GLECLALNCFNLKRLSLKSCESITGQGLQIVAANCFDLQTLNV 461
Score = 47.4 bits (111), Expect = 1e-04
Identities = 49/220 (22%), Positives = 85/220 (38%), Gaps = 24/220 (10%)
Query: 296 FRISDQFLSSIAMESLPLRRLVLSYCPGYTYSGISFLLSKSKRIQHLDLQYTDFLNDHCV 355
F + D+ L +IA L L L C T G+ +L+ I+ L + F++D +
Sbjct: 283 FVLEDEGLHTIAAHCTQLTHLYLRRCVRLTDEGLRYLVIYCASIKELSVSDCRFVSDFGL 342
Query: 356 AELSLFLGDLLSLNLGNCRLLTVSTFFALITNCPSLTEINMNRTNIQGTTIPNSLMDRLV 415
E++ L L++ +C +T + C L +N +G T
Sbjct: 343 REIAKLESRLRYLSIAHCGRVTDVGIRYVAKYCSKLRYLNAR--GCEGITDHGVEYLAKN 400
Query: 416 NPQFKSLFLASAACLEDQNIIMFAALFPNLQQLHLSCSYNITEEGIRPLLESCRKIRHLN 475
+ KSL + + D + A NL++L L +IT +G++ + +C
Sbjct: 401 CTKLKSLDIGKCPLVSDTGLECLALNCFNLKRLSLKSCESITGQGLQIVAANCF------ 454
Query: 476 LTCLSLKSLGTNFDLPDLEVLNLTNTEVDDEALYIISNRC 515
DL+ LN+ + EV EAL + C
Sbjct: 455 ----------------DLQTLNVQDCEVSVEALRFVKRHC 478
Score = 40.0 bits (92), Expect = 0.017
Identities = 47/243 (19%), Positives = 91/243 (37%), Gaps = 43/243 (17%)
Query: 119 LKLTSLNLSNQLILPANGLRAFSQNITTLTSLICSNLISLNSTDIHLIADTFPLLEELDL 178
+ + L++++ +L GL + + T LT L + L + + ++EL
Sbjct: 272 ISIRYLDMTDCFVLEDEGLHTIAAHCTQLTHLYLRRCVRLTDEGLRYLVIYCASIKELS- 330
Query: 179 AYPSKIINHTHATFSTGLEALSLALIKLRKVNLSYHGYLNGTLLSHLFKNCKFLQEVILL 238
++ GL ++ +LR +++++ G + + ++ K C L+ +
Sbjct: 331 ------VSDCRFVSDFGLREIAKLESRLRYLSIAHCGRVTDVGIRYVAKYCSKLRYLNAR 384
Query: 239 RCEQLTIAGVDLALLQKPTLTSLSITCTVTTGLEHLTSHFIDSLLSLKGLTSLLLTGFRI 298
CE +T GV+ L SL I G L +
Sbjct: 385 GCEGITDHGVEYLAKNCTKLKSLDI-----------------------GKCPL------V 415
Query: 299 SDQFLSSIAMESLPLRRLVLSYCPGYTYSGISFLLSKSKRIQHLDLQYTD-------FLN 351
SD L +A+ L+RL L C T G+ + + +Q L++Q + F+
Sbjct: 416 SDTGLECLALNCFNLKRLSLKSCESITGQGLQIVAANCFDLQTLNVQDCEVSVEALRFVK 475
Query: 352 DHC 354
HC
Sbjct: 476 RHC 478
Score = 39.3 bits (90), Expect = 0.030
Identities = 23/89 (25%), Positives = 43/89 (47%), Gaps = 9/89 (10%)
Query: 496 LNLTNTEVD-DEALYIISNR--------CPALLQLVLLRCDYITDKGVMHVVNNCTQLRE 546
+ LT ++ D AL +++ R C L + + C +TD+G+ + C +LR
Sbjct: 157 IRLTGETINVDRALKVLTRRLCQDTPNVCLMLETVTVSGCRRLTDRGLYTIAQCCPELRR 216
Query: 547 INLDGCPNVQAKVVASMVVSRPSLRKIHV 575
+ + GC N+ + V +V P+L + V
Sbjct: 217 LEVSGCYNISNEAVFDVVSLCPNLEHLDV 245
>FXLK_RAT (Q9QZH7) F-box/LRR-repeat protein 20 (F-box and
leucine-rich repeat protein 20) (F-box/LRR-repeat
protein 2-like)
Length = 276
Score = 65.5 bits (158), Expect = 4e-10
Identities = 53/212 (25%), Positives = 95/212 (44%), Gaps = 29/212 (13%)
Query: 363 GDLLSLNLGNCRLLTVSTFFALITNCPSLTEINMN---RTNIQGTTIPNSLMDRLVNPQF 419
G L L+L C + + NC ++ +++N +T T + +L
Sbjct: 91 GFLRKLSLRGCLGVGDNALRTFAQNCRNIEVLSLNGCTKTTDATCTSLSKFCSKL----- 145
Query: 420 KSLFLASAACLEDQNIIMFAALFPNLQQLHLSCSYNITEEGIRPLLESCRKIRHLNLTCL 479
+ L LAS + + ++ + P L+QL++S +T++GI+ L+ C L L
Sbjct: 146 RHLDLASCTSITNMSLKALSEGCPLLEQLNISWCDQVTKDGIQALVRGCG-----GLKAL 200
Query: 480 SLKSLGTNFDLPDLEVLNLTNTEVDDEALYIISNRCPALLQLVLLRCDYITDKGVMHVVN 539
LK T+++DEAL I CP L+ L L C ITD+G++ +
Sbjct: 201 FLKGC----------------TQLEDEALKYIGAHCPELVTLNLQTCLQITDEGLITICR 244
Query: 540 NCTQLREINLDGCPNVQAKVVASMVVSRPSLR 571
C +L+ + GC N+ ++ ++ + P LR
Sbjct: 245 GCHKLQSLCASGCSNITDAILNALGQNCPRLR 276
Score = 61.6 bits (148), Expect = 6e-09
Identities = 51/183 (27%), Positives = 78/183 (41%), Gaps = 12/183 (6%)
Query: 313 LRRLVLSYCPGYTYSGISFLLSKSKRIQHLDLQYTDFLNDHCVAELSLFLGDLLSLNLGN 372
LR+L L C G + + + I+ L L D LS F L L+L +
Sbjct: 93 LRKLSLRGCLGVGDNALRTFAQNCRNIEVLSLNGCTKTTDATCTSLSKFCSKLRHLDLAS 152
Query: 373 CRLLTVSTFFALITNCPSLTEINMNRTNIQGTTIPNSLMDRLVN--PQFKSLFLASAACL 430
C +T + AL CP L ++N++ + + + LV K+LFL L
Sbjct: 153 CTSITNMSLKALSEGCPLLEQLNISWCD----QVTKDGIQALVRGCGGLKALFLKGCTQL 208
Query: 431 EDQNIIMFAALFPNLQQLHLSCSYNITEEGIRPLLESCRKIRHL------NLTCLSLKSL 484
ED+ + A P L L+L IT+EG+ + C K++ L N+T L +L
Sbjct: 209 EDEALKYIGAHCPELVTLNLQTCLQITDEGLITICRGCHKLQSLCASGCSNITDAILNAL 268
Query: 485 GTN 487
G N
Sbjct: 269 GQN 271
Score = 52.0 bits (123), Expect = 4e-06
Identities = 39/159 (24%), Positives = 69/159 (42%), Gaps = 14/159 (8%)
Query: 445 LQQLHLSCSYNITEEGIRPLLESCRKIRHLNL---------TCLSLKSLGTNFDLPDLEV 495
L++L L + + +R ++CR I L+L TC SL + DL
Sbjct: 93 LRKLSLRGCLGVGDNALRTFAQNCRNIEVLSLNGCTKTTDATCTSLSKFCSKLRHLDLA- 151
Query: 496 LNLTNTEVDDEALYIISNRCPALLQLVLLRCDYITDKGVMHVVNNCTQLREINLDGCPNV 555
+ T + + +L +S CP L QL + CD +T G+ +V C L+ + L GC +
Sbjct: 152 ---SCTSITNMSLKALSEGCPLLEQLNISWCDQVTKDGIQALVRGCGGLKALFLKGCTQL 208
Query: 556 QAKVVASMVVSRPSLRKIHVPPNFPLSDRNRKLFSRHGC 594
+ + + + P L +++ ++D R GC
Sbjct: 209 EDEALKYIGAHCPELVTLNLQTCLQITDEGLITICR-GC 246
Score = 32.7 bits (73), Expect = 2.8
Identities = 31/138 (22%), Positives = 58/138 (41%), Gaps = 15/138 (10%)
Query: 119 LKLTSLNLSNQLILPANGLRAFSQNITTLTSLICSNL--------ISLNSTDIHLIADTF 170
L+ + N N +L NG + T S CS L S+ + + +++
Sbjct: 109 LRTFAQNCRNIEVLSLNGCTKTTDATCTSLSKFCSKLRHLDLASCTSITNMSLKALSEGC 168
Query: 171 PLLEELDLAYPSKIINHTHATFSTGLEALSLALIKLRKVNLSYHGYLNGTLLSHLFKNCK 230
PLLE+L++++ ++ G++AL L+ + L L L ++ +C
Sbjct: 169 PLLEQLNISWCDQVT-------KDGIQALVRGCGGLKALFLKGCTQLEDEALKYIGAHCP 221
Query: 231 FLQEVILLRCEQLTIAGV 248
L + L C Q+T G+
Sbjct: 222 ELVTLNLQTCLQITDEGL 239
>FXLE_MOUSE (Q8BID8) F-box/LRR-repeat protein 14 (F-box and
leucine-rich repeat protein 14)
Length = 400
Score = 61.6 bits (148), Expect = 6e-09
Identities = 78/259 (30%), Positives = 108/259 (41%), Gaps = 31/259 (11%)
Query: 118 MLKLTSLNLSNQLILPANGL-RAFSQNITTLTSLICSNLISLNSTDIHLIADTFPLLEEL 176
M + SLNLS L NGL AF Q I +L +L S + + + IA LE L
Sbjct: 89 MANIESLNLSGCYNLTDNGLGHAFVQEIGSLRALNLSLCKQITDSSLGRIAQYLKGLEVL 148
Query: 177 DLAYPSKIINHTHATFSTGLEALSLALIKLRKVNLSYHGYLNGTLLSHLFKNCKFLQEVI 236
+L S I N TGL ++ L +L+ +NL +L+ + HL + E
Sbjct: 149 ELGGCSNITN-------TGLLLIAWGLQRLKSLNLRSCRHLSDVGIGHLAGMTRSAAEGC 201
Query: 237 LLRCEQLTIAGVDLALLQKPTLTSLSITCTVTTGLEHLTSHFIDSLLSLKGLTSLLLTGF 296
L EQLT+ QK T SL TGL L F + S GL L G
Sbjct: 202 L-GLEQLTLQDC-----QKLTDLSLKHISRGLTGLRLLNLSFCGGI-SDAGLLHLSHMG- 253
Query: 297 RISDQFLSSIAMESLPLRRLVLSYCPGYTYSGISFLLSKSKRIQHLDLQYTDFLNDHCVA 356
LR L L C + +GI L S R+ LD+ + D + D +A
Sbjct: 254 ---------------SLRSLNLRSCDNISDTGIMHLAMGSLRLSGLDVSFCDKVGDQSLA 298
Query: 357 ELSLFLGDLLSLNLGNCRL 375
++ L L SL+L +C +
Sbjct: 299 YIAQGLDGLKSLSLCSCHI 317
Score = 50.4 bits (119), Expect = 1e-05
Identities = 67/292 (22%), Positives = 125/292 (41%), Gaps = 35/292 (11%)
Query: 270 GLEHLTSHFIDSLLSLKGLTSLLLTGFRISDQFLSSIAMESLPLRRLVLSYCPGYTYSGI 329
GL H F+ + SL+ L L +I+D L IA L L L C T +G+
Sbjct: 107 GLGHA---FVQEIGSLRALNLSLCK--QITDSSLGRIAQYLKGLEVLELGGCSNITNTGL 161
Query: 330 SFLLSKSKRIQHLDLQYTDFLNDHCVAELSLFLGDLLSLNLGNCRLLTVSTFFALITNCP 389
+ +R++ L+L+ L+D + L+ LG +L + +C
Sbjct: 162 LLIAWGLQRLKSLNLRSCRHLSDVGIGHLAGMTRSAAEGCLGLEQLT--------LQDCQ 213
Query: 390 SLTEINMNRTNIQGTTIPNSLMDRLVNPQFKSLFLASAACLEDQNIIMFAALFPNLQQLH 449
LT++++ + T + RL+N F + D ++ + + +L+ L+
Sbjct: 214 KLTDLSLKHISRGLTGL------RLLNLSF-------CGGISDAGLLHLSHM-GSLRSLN 259
Query: 450 LSCSYNITEEGIRPLLESCRKIRHLNLTCL------SLKSLGTNFDLPDLEVLNLTNTEV 503
L NI++ GI L ++ L+++ SL + D L+ L+L + +
Sbjct: 260 LRSCDNISDTGIMHLAMGSLRLSGLDVSFCDKVGDQSLAYIAQGLD--GLKSLSLCSCHI 317
Query: 504 DDEALYIISNRCPALLQLVLLRCDYITDKGVMHVVNNCTQLREINLDGCPNV 555
D+ + + + L L + +C ITDKG+ + + +QL I+L GC +
Sbjct: 318 SDDGINRMVRQMHGLRTLNIGQCVRITDKGLELIAEHLSQLTGIDLYGCTRI 369
Score = 45.4 bits (106), Expect = 4e-04
Identities = 53/228 (23%), Positives = 97/228 (42%), Gaps = 22/228 (9%)
Query: 362 LGDLLSLNLGNCRLLTVSTF-FALITNCPSLTEINMNRTNIQGTTIPNSLMDRLVN--PQ 418
+ ++ SLNL C LT + A + SL +N++ I +S + R+
Sbjct: 89 MANIESLNLSGCYNLTDNGLGHAFVQEIGSLRALNLSLCK----QITDSSLGRIAQYLKG 144
Query: 419 FKSLFLASAACLEDQNIIMFAALFPNLQQLHLSCSYNITEEGI-------RPLLESCRKI 471
+ L L + + + +++ A L+ L+L ++++ GI R E C +
Sbjct: 145 LEVLELGGCSNITNTGLLLIAWGLQRLKSLNLRSCRHLSDVGIGHLAGMTRSAAEGCLGL 204
Query: 472 RHLNL------TCLSLKSLGTNFDLPDLEVLNLTNTEVDDEALYIISNRCPALLQLVLLR 525
L L T LSLK + L L +LNL+ +A + + +L L L
Sbjct: 205 EQLTLQDCQKLTDLSLKHISRG--LTGLRLLNLSFCGGISDAGLLHLSHMGSLRSLNLRS 262
Query: 526 CDYITDKGVMHVVNNCTQLREINLDGCPNVQAKVVASMVVSRPSLRKI 573
CD I+D G+MH+ +L +++ C V + +A + L+ +
Sbjct: 263 CDNISDTGIMHLAMGSLRLSGLDVSFCDKVGDQSLAYIAQGLDGLKSL 310
>FXLE_HUMAN (Q8N1E6) F-box/LRR-repeat protein 14 (F-box and
leucine-rich repeat protein 14)
Length = 418
Score = 61.6 bits (148), Expect = 6e-09
Identities = 78/259 (30%), Positives = 108/259 (41%), Gaps = 31/259 (11%)
Query: 118 MLKLTSLNLSNQLILPANGL-RAFSQNITTLTSLICSNLISLNSTDIHLIADTFPLLEEL 176
M + SLNLS L NGL AF Q I +L +L S + + + IA LE L
Sbjct: 89 MANIESLNLSGCYNLTDNGLGHAFVQEIGSLRALNLSLCKQITDSSLGRIAQYLKGLEVL 148
Query: 177 DLAYPSKIINHTHATFSTGLEALSLALIKLRKVNLSYHGYLNGTLLSHLFKNCKFLQEVI 236
+L S I N TGL ++ L +L+ +NL +L+ + HL + E
Sbjct: 149 ELGGCSNITN-------TGLLLIAWGLQRLKSLNLRSCRHLSDVGIGHLAGMTRSAAEGC 201
Query: 237 LLRCEQLTIAGVDLALLQKPTLTSLSITCTVTTGLEHLTSHFIDSLLSLKGLTSLLLTGF 296
L EQLT+ QK T SL TGL L F + S GL L G
Sbjct: 202 L-GLEQLTLQDC-----QKLTDLSLKHISRGLTGLRLLNLSFCGGI-SDAGLLHLSHMG- 253
Query: 297 RISDQFLSSIAMESLPLRRLVLSYCPGYTYSGISFLLSKSKRIQHLDLQYTDFLNDHCVA 356
LR L L C + +GI L S R+ LD+ + D + D +A
Sbjct: 254 ---------------SLRSLNLRSCDNISDTGIMHLAMGSLRLSGLDVSFCDKVGDQSLA 298
Query: 357 ELSLFLGDLLSLNLGNCRL 375
++ L L SL+L +C +
Sbjct: 299 YIAQGLDGLKSLSLCSCHI 317
Score = 50.4 bits (119), Expect = 1e-05
Identities = 67/292 (22%), Positives = 125/292 (41%), Gaps = 35/292 (11%)
Query: 270 GLEHLTSHFIDSLLSLKGLTSLLLTGFRISDQFLSSIAMESLPLRRLVLSYCPGYTYSGI 329
GL H F+ + SL+ L L +I+D L IA L L L C T +G+
Sbjct: 107 GLGHA---FVQEIGSLRALNLSLCK--QITDSSLGRIAQYLKGLEVLELGGCSNITNTGL 161
Query: 330 SFLLSKSKRIQHLDLQYTDFLNDHCVAELSLFLGDLLSLNLGNCRLLTVSTFFALITNCP 389
+ +R++ L+L+ L+D + L+ LG +L + +C
Sbjct: 162 LLIAWGLQRLKSLNLRSCRHLSDVGIGHLAGMTRSAAEGCLGLEQLT--------LQDCQ 213
Query: 390 SLTEINMNRTNIQGTTIPNSLMDRLVNPQFKSLFLASAACLEDQNIIMFAALFPNLQQLH 449
LT++++ + T + RL+N F + D ++ + + +L+ L+
Sbjct: 214 KLTDLSLKHISRGLTGL------RLLNLSF-------CGGISDAGLLHLSHM-GSLRSLN 259
Query: 450 LSCSYNITEEGIRPLLESCRKIRHLNLTCL------SLKSLGTNFDLPDLEVLNLTNTEV 503
L NI++ GI L ++ L+++ SL + D L+ L+L + +
Sbjct: 260 LRSCDNISDTGIMHLAMGSLRLSGLDVSFCDKVGDQSLAYIAQGLD--GLKSLSLCSCHI 317
Query: 504 DDEALYIISNRCPALLQLVLLRCDYITDKGVMHVVNNCTQLREINLDGCPNV 555
D+ + + + L L + +C ITDKG+ + + +QL I+L GC +
Sbjct: 318 SDDGINRMVRQMHGLRTLNIGQCVRITDKGLELIAEHLSQLTGIDLYGCTRI 369
Score = 45.4 bits (106), Expect = 4e-04
Identities = 53/228 (23%), Positives = 97/228 (42%), Gaps = 22/228 (9%)
Query: 362 LGDLLSLNLGNCRLLTVSTF-FALITNCPSLTEINMNRTNIQGTTIPNSLMDRLVN--PQ 418
+ ++ SLNL C LT + A + SL +N++ I +S + R+
Sbjct: 89 MANIESLNLSGCYNLTDNGLGHAFVQEIGSLRALNLSLCK----QITDSSLGRIAQYLKG 144
Query: 419 FKSLFLASAACLEDQNIIMFAALFPNLQQLHLSCSYNITEEGI-------RPLLESCRKI 471
+ L L + + + +++ A L+ L+L ++++ GI R E C +
Sbjct: 145 LEVLELGGCSNITNTGLLLIAWGLQRLKSLNLRSCRHLSDVGIGHLAGMTRSAAEGCLGL 204
Query: 472 RHLNL------TCLSLKSLGTNFDLPDLEVLNLTNTEVDDEALYIISNRCPALLQLVLLR 525
L L T LSLK + L L +LNL+ +A + + +L L L
Sbjct: 205 EQLTLQDCQKLTDLSLKHISRG--LTGLRLLNLSFCGGISDAGLLHLSHMGSLRSLNLRS 262
Query: 526 CDYITDKGVMHVVNNCTQLREINLDGCPNVQAKVVASMVVSRPSLRKI 573
CD I+D G+MH+ +L +++ C V + +A + L+ +
Sbjct: 263 CDNISDTGIMHLAMGSLRLSGLDVSFCDKVGDQSLAYIAQGLDGLKSL 310
>FX37_MOUSE (Q91W61) F-box only protein 37 (F-box/LRR-repeat protein
15)
Length = 296
Score = 60.8 bits (146), Expect = 1e-08
Identities = 53/184 (28%), Positives = 86/184 (45%), Gaps = 13/184 (7%)
Query: 403 GTTIPNSLMDRLVNPQFKSLFLASAAC---LEDQNIIMFAALFPNLQQLHLSCSYNITEE 459
G IP + + RL+ LA A C L D++++ A P L+ + L+ ++
Sbjct: 67 GPQIPRAALARLLRDAEGLQELALAPCHEWLSDEDLVPVLARNPQLRSVALAGCGQLSRR 126
Query: 460 GIRPLLESCRKIRHLNLT-C-----LSLKSLGTNFDLPDLEVLNLTNT-EVDDEAL-YII 511
+ L E C +++ L+L C L+L+ L P LE L+LT ++ DEA+ Y+
Sbjct: 127 ALGALAEGCPRLQRLSLAHCDWVDGLALRGLADR--CPALEELDLTACRQLKDEAIVYLA 184
Query: 512 SNRCPALLQLVLLRCDYITDKGVMHVVNNCTQLREINLDGCPNVQAKVVASMVVSRPSLR 571
R L L L + D V + NC QL ++L GC V + V ++ P+LR
Sbjct: 185 QRRGAGLRSLSLAVNANVGDTAVQELARNCPQLEHLDLTGCLRVGSDGVRTLAEYCPALR 244
Query: 572 KIHV 575
+ V
Sbjct: 245 SLRV 248
Score = 35.4 bits (80), Expect = 0.43
Identities = 56/226 (24%), Positives = 92/226 (39%), Gaps = 25/226 (11%)
Query: 51 RYLKSLSVASKHFLSVTNRH-----KFCLTILYPALP--VLPGLLQRFTKLTSLDLSYYY 103
R L L S+ F ++ H +F + P +P L LL+ L L L+ +
Sbjct: 35 RQLLRLQRVSRAFRALVQLHLARLRRFDAAQVGPQIPRAALARLLRDAEGLQELALAPCH 94
Query: 104 GDL--DALLTQISSFPMLKLTSLNLSNQLILPANGLRAFSQNITTLTSLICSNLISLNST 161
L + L+ ++ P L+ +L QL A G A ++ L L ++ ++
Sbjct: 95 EWLSDEDLVPVLARNPQLRSVALAGCGQLSRRALG--ALAEGCPRLQRLSLAHCDWVDGL 152
Query: 162 DIHLIADTFPLLEELDLA----YPSKIINHTHATFSTGLEALSLALIKLRKVNLSYHGYL 217
+ +AD P LEELDL + I + GL +LSLA+ + +
Sbjct: 153 ALRGLADRCPALEELDLTACRQLKDEAIVYLAQRRGAGLRSLSLAV----------NANV 202
Query: 218 NGTLLSHLFKNCKFLQEVILLRCEQLTIAGVDLALLQKPTLTSLSI 263
T + L +NC L+ + L C ++ GV P L SL +
Sbjct: 203 GDTAVQELARNCPQLEHLDLTGCLRVGSDGVRTLAEYCPALRSLRV 248
Score = 32.0 bits (71), Expect = 4.7
Identities = 35/128 (27%), Positives = 59/128 (45%), Gaps = 6/128 (4%)
Query: 196 LEALSLALIKLRKVNLSYHGYLNGTLLSHLFKNCKFLQEVILLRCEQL-TIAGVDLALLQ 254
L AL+ +L++++L++ +++G L L C L+E+ L C QL A V LA +
Sbjct: 128 LGALAEGCPRLQRLSLAHCDWVDGLALRGLADRCPALEELDLTACRQLKDEAIVYLAQRR 187
Query: 255 KPTLTSLSITCTVTTGLEHLTSHFIDSLLSLKGLTSLLLTG-FRISDQFLSSIAMESLPL 313
L SLS+ G + + + L L LTG R+ + ++A L
Sbjct: 188 GAGLRSLSLAVNANVG----DTAVQELARNCPQLEHLDLTGCLRVGSDGVRTLAEYCPAL 243
Query: 314 RRLVLSYC 321
R L + +C
Sbjct: 244 RSLRVRHC 251
>FXLH_MOUSE (Q9QZN1) F-box/LRR-repeat protein 17 (F-box and
leucine-rich repeat protein 17) (F-box only protein 13)
(Fragment)
Length = 462
Score = 58.5 bits (140), Expect = 5e-08
Identities = 51/233 (21%), Positives = 105/233 (44%), Gaps = 5/233 (2%)
Query: 332 LLSKSKRIQHLDLQYTDFLNDHCVAELSLFLGDLLSLNLGNCRLLTVSTFFALITNCPSL 391
+ S+S+ I +++ L+D V L+ LL C+ L+ ++ A+ ++CP L
Sbjct: 142 IASRSQNIIEINISDCRSLSDSGVCVLAFKCPGLLRYTAYRCKQLSDTSIIAVASHCPLL 201
Query: 392 TEINMNRTNIQGTTIPNSLMDRLVNPQFKSLFLASAACLEDQNIIMFAALFPNLQQLHLS 451
++++ + L R + K + + D+ +I+ A LQ++++
Sbjct: 202 QKVHVGNQDKLTDEGLKQLGSRC--RELKDIHFGQCYKISDEGMIVIAKSCLKLQRIYMQ 259
Query: 452 CSYNITEEGIRPLLESCRKIRHLNLTCLSLKSLGTNF--DLPDLEVLNLTN-TEVDDEAL 508
+ +T++ ++ E C +++++ S+ S G L +L L+L + TE+D+E +
Sbjct: 260 ENKLVTDQSVKAFAEHCPELQYVGFMGCSVTSKGVIHLTKLRNLSSLDLRHITELDNETV 319
Query: 509 YIISNRCPALLQLVLLRCDYITDKGVMHVVNNCTQLREINLDGCPNVQAKVVA 561
I RC L L L I D+ V + L+E+ L C ++A
Sbjct: 320 MEIVKRCKNLSSLNLCLNWIINDRCVEVIAKEGQNLKELYLVSCKITDYALIA 372
Score = 57.8 bits (138), Expect = 8e-08
Identities = 48/254 (18%), Positives = 106/254 (40%), Gaps = 25/254 (9%)
Query: 340 QHLDLQYTDFLNDHCVAELSLFLGDLLSLNLGNCRLLTVSTFFALITNCPSLTEINMNRT 399
+ LDL + D + +++ +++ +N+ +CR L+ S L CP L R
Sbjct: 124 KQLDLSSRQQVTDELLEKIASRSQNIIEINISDCRSLSDSGVCVLAFKCPGLLRYTAYRC 183
Query: 400 NIQGTTIPNSLMDRLVNPQFKSLFLASAACLEDQNIIMFAALFPNLQQLHLSCSYNITEE 459
T ++ P + + + + L D+ + + L+ +H Y I++E
Sbjct: 184 KQLSDTSIIAVASHC--PLLQKVHVGNQDKLTDEGLKQLGSRCRELKDIHFGQCYKISDE 241
Query: 460 GIRPLLESCRKIRHLNLTCLSLKSLGTNFDLPDLEVLNLTNTEVDDEALYIISNRCPALL 519
G+ + +SC K++ + + N V D+++ + CP L
Sbjct: 242 GMIVIAKSCLKLQRIYMQ---------------------ENKLVTDQSVKAFAEHCPELQ 280
Query: 520 QLVLLRCDYITDKGVMHVVNNCTQLREINLDGCPNVQAKVVASMVVSRPSLRKIHVPPNF 579
+ + C +T KGV+H + L ++L + + V +V +L +++ N+
Sbjct: 281 YVGFMGCS-VTSKGVIH-LTKLRNLSSLDLRHITELDNETVMEIVKRCKNLSSLNLCLNW 338
Query: 580 PLSDRNRKLFSRHG 593
++DR ++ ++ G
Sbjct: 339 IINDRCVEVIAKEG 352
Score = 41.6 bits (96), Expect = 0.006
Identities = 57/301 (18%), Positives = 119/301 (38%), Gaps = 40/301 (13%)
Query: 97 LDLSYYYGDLDALLTQISSFPMLKLTSLNLSNQLILPANGLRAFSQNITTLTSLICSNLI 156
LDLS D LL +I+S + +N+S+ L +G+ + L
Sbjct: 126 LDLSSRQQVTDELLEKIASRSQ-NIIEINISDCRSLSDSGVCVLAFKCPGLLRYTAYRCK 184
Query: 157 SLNSTDIHLIADTFPLLEELDLAYPSKIINH-------------------THATFSTGLE 197
L+ T I +A PLL+++ + K+ + + G+
Sbjct: 185 QLSDTSIIAVASHCPLLQKVHVGNQDKLTDEGLKQLGSRCRELKDIHFGQCYKISDEGMI 244
Query: 198 ALSLALIKLRKVNLSYHGYLNGTLLSHLFKNCKFLQEVILLRCEQLT-----------IA 246
++ + +KL+++ + + + + ++C LQ V + C + ++
Sbjct: 245 VIAKSCLKLQRIYMQENKLVTDQSVKAFAEHCPELQYVGFMGCSVTSKGVIHLTKLRNLS 304
Query: 247 GVDL---ALLQKPTLTSLSITCTVTTGLEHLTSHFIDS----LLSLKG--LTSLLLTGFR 297
+DL L T+ + C + L + I+ +++ +G L L L +
Sbjct: 305 SLDLRHITELDNETVMEIVKRCKNLSSLNLCLNWIINDRCVEVIAKEGQNLKELYLVSCK 364
Query: 298 ISDQFLSSIAMESLPLRRLVLSYCPGYTYSGISFLLSKSKRIQHLDLQYTDFLNDHCVAE 357
I+D L +I S+ + + + +C T G + + SK +++L L D +N+ V +
Sbjct: 365 ITDYALIAIGRYSVTIETVDVGWCKEITDQGATLIAQSSKSLRYLGLMRCDKVNELTVEQ 424
Query: 358 L 358
L
Sbjct: 425 L 425
Score = 35.4 bits (80), Expect = 0.43
Identities = 51/272 (18%), Positives = 97/272 (34%), Gaps = 36/272 (13%)
Query: 298 ISDQFLSSIAMESLPLRRLVLSYCPGYTYSGISFLLSKSKRIQHLDLQYTDFLNDHCVAE 357
+SD + +A + L R C + + I + S +Q + + D L D + +
Sbjct: 160 LSDSGVCVLAFKCPGLLRYTAYRCKQLSDTSIIAVASHCPLLQKVHVGNQDKLTDEGLKQ 219
Query: 358 LSLFLGDLLSLNLGNCRLLTVSTFFALITNCPSLTEINMNRTNIQGTTIPNSLMDRLVNP 417
L +L ++ G C ++ + +C L I M + + +
Sbjct: 220 LGSRCRELKDIHFGQCYKISDEGMIVIAKSCLKLQRIYMQENKLVTDQSVKAFAEHCPEL 279
Query: 418 QFKSLFLASAACLEDQNIIMFAALFPNLQQLHLSCSYNITEEGIRPLLESCRKIRHLNLT 477
Q+ C ++ NL L L + E + +++ C+ + LNL
Sbjct: 280 QYVGFM----GCSVTSKGVIHLTKLRNLSSLDLRHITELDNETVMEIVKRCKNLSSLNL- 334
Query: 478 CLS-----------------LKSLG------TNFDLPDLEVLNLTNTEVD--------DE 506
CL+ LK L T++ L + ++T VD D+
Sbjct: 335 CLNWIINDRCVEVIAKEGQNLKELYLVSCKITDYALIAIGRYSVTIETVDVGWCKEITDQ 394
Query: 507 ALYIISNRCPALLQLVLLRCDYITDKGVMHVV 538
+I+ +L L L+RCD + + V +V
Sbjct: 395 GATLIAQSSKSLRYLGLMRCDKVNELTVEQLV 426
>FX37_HUMAN (Q9H469) F-box only protein 37 (F-box/LRR-repeat protein
15)
Length = 296
Score = 58.2 bits (139), Expect = 6e-08
Identities = 52/184 (28%), Positives = 84/184 (45%), Gaps = 13/184 (7%)
Query: 403 GTTIPNSLMDRLVNPQFKSLFLASAAC---LEDQNIIMFAALFPNLQQLHLSCSYNITEE 459
G IP + + RL+ LA A C L D++++ A P L+ + L ++
Sbjct: 67 GPQIPRAALARLLRDAEGLQELALAPCHEWLSDEDLVPVLARNPQLRSVALGGCGQLSRR 126
Query: 460 GIRPLLESCRKIRHLNLT-C-----LSLKSLGTNFDLPDLEVLNLTNT-EVDDEAL-YII 511
+ L E C +++ L+L C L+L+ L P LE L+LT ++ DEA+ Y+
Sbjct: 127 ALGALAEGCPRLQRLSLAHCDWVDGLALRGLADR--CPALEELDLTACRQLKDEAIVYLA 184
Query: 512 SNRCPALLQLVLLRCDYITDKGVMHVVNNCTQLREINLDGCPNVQAKVVASMVVSRPSLR 571
R L L L + D V + NC +L ++L GC V + V ++ P LR
Sbjct: 185 QRRGAGLRSLSLAVNANVGDAAVQELARNCPELHHLDLTGCLRVGSDGVRTLAEYCPVLR 244
Query: 572 KIHV 575
+ V
Sbjct: 245 SLRV 248
Score = 52.0 bits (123), Expect = 4e-06
Identities = 54/242 (22%), Positives = 100/242 (41%), Gaps = 28/242 (11%)
Query: 297 RISDQFLSSIAMESLPLRRLVLSYC-PGYTYSGISFLLSKSKRIQHLDLQYT-DFLNDHC 354
R+S F S + + LRR + P + ++ LL ++ +Q L L ++L+D
Sbjct: 42 RVSRAFRSLVQLHLAGLRRFDAAQVGPQIPRAALARLLRDAEGLQELALAPCHEWLSDED 101
Query: 355 VAELSLFLGDLLSLNLGNCRLLTVSTFFALITNCPSLTEINMNRTNIQGTTIPNSLMDRL 414
+ + L S+ LG C L+ AL CP L +++ + L DR
Sbjct: 102 LVPVLARNPQLRSVALGGCGQLSRRALGALAEGCPRLQRLSLAHCDWVDGLALRGLADRC 161
Query: 415 VNPQFKSLFLASAACLEDQNIIMFA-ALFPNLQQLHLSCSYNITEEGIRPLLESCRKIRH 473
P + L L + L+D+ I+ A L+ L L+ + N+ + ++ L +C ++ H
Sbjct: 162 --PALEELDLTACRQLKDEAIVYLAQRRGAGLRSLSLAVNANVGDAAVQELARNCPELHH 219
Query: 474 LNLT-CLSLKSLGTNFDLPDLEVLNLTNTEVDDEALYIISNRCPALLQLVLLRCDYITDK 532
L+LT CL V + + ++ CP L L + C ++ +
Sbjct: 220 LDLTGCL----------------------RVGSDGVRTLAEYCPVLRSLRVRHCHHVAES 257
Query: 533 GV 534
+
Sbjct: 258 SL 259
Score = 37.0 bits (84), Expect = 0.15
Identities = 19/83 (22%), Positives = 39/83 (46%), Gaps = 1/83 (1%)
Query: 502 EVDDEALYIISNRCPALLQLVLLRCDYITDKGVMHVVNNCTQLREINLDGCPNVQAKVVA 561
++ AL ++ CP L +L L CD++ + + + C L E++L C ++ + +
Sbjct: 122 QLSRRALGALAEGCPRLQRLSLAHCDWVDGLALRGLADRCPALEELDLTACRQLKDEAIV 181
Query: 562 SMVVSR-PSLRKIHVPPNFPLSD 583
+ R LR + + N + D
Sbjct: 182 YLAQRRGAGLRSLSLAVNANVGD 204
Score = 34.7 bits (78), Expect = 0.73
Identities = 56/226 (24%), Positives = 90/226 (39%), Gaps = 25/226 (11%)
Query: 51 RYLKSLSVASKHFLSVTNRH-----KFCLTILYPALP--VLPGLLQRFTKLTSLDLSYYY 103
R L L S+ F S+ H +F + P +P L LL+ L L L+ +
Sbjct: 35 RQLLRLQRVSRAFRSLVQLHLAGLRRFDAAQVGPQIPRAALARLLRDAEGLQELALAPCH 94
Query: 104 GDL--DALLTQISSFPMLKLTSLNLSNQLILPANGLRAFSQNITTLTSLICSNLISLNST 161
L + L+ ++ P L+ +L QL A G A ++ L L ++ ++
Sbjct: 95 EWLSDEDLVPVLARNPQLRSVALGGCGQLSRRALG--ALAEGCPRLQRLSLAHCDWVDGL 152
Query: 162 DIHLIADTFPLLEELDLA----YPSKIINHTHATFSTGLEALSLALIKLRKVNLSYHGYL 217
+ +AD P LEELDL + I + GL +LSLA+ + +
Sbjct: 153 ALRGLADRCPALEELDLTACRQLKDEAIVYLAQRRGAGLRSLSLAV----------NANV 202
Query: 218 NGTLLSHLFKNCKFLQEVILLRCEQLTIAGVDLALLQKPTLTSLSI 263
+ L +NC L + L C ++ GV P L SL +
Sbjct: 203 GDAAVQELARNCPELHHLDLTGCLRVGSDGVRTLAEYCPVLRSLRV 248
Score = 32.7 bits (73), Expect = 2.8
Identities = 38/139 (27%), Positives = 63/139 (44%), Gaps = 6/139 (4%)
Query: 196 LEALSLALIKLRKVNLSYHGYLNGTLLSHLFKNCKFLQEVILLRCEQL-TIAGVDLALLQ 254
L AL+ +L++++L++ +++G L L C L+E+ L C QL A V LA +
Sbjct: 128 LGALAEGCPRLQRLSLAHCDWVDGLALRGLADRCPALEELDLTACRQLKDEAIVYLAQRR 187
Query: 255 KPTLTSLSITCTVTTGLEHLTSHFIDSLLSLKGLTSLLLTG-FRISDQFLSSIAMESLPL 313
L SLS+ G + + + L L LTG R+ + ++A L
Sbjct: 188 GAGLRSLSLAVNANVG----DAAVQELARNCPELHHLDLTGCLRVGSDGVRTLAEYCPVL 243
Query: 314 RRLVLSYCPGYTYSGISFL 332
R L + +C S +S L
Sbjct: 244 RSLRVRHCHHVAESSLSRL 262
>FXLH_HUMAN (Q9UF56) F-box/LRR-repeat protein 17 (F-box and
leucine-rich repeat protein 17) (F-box only protein 13)
(Fragment)
Length = 370
Score = 57.8 bits (138), Expect = 8e-08
Identities = 52/236 (22%), Positives = 107/236 (45%), Gaps = 11/236 (4%)
Query: 332 LLSKSKRIQHLDLQYTDFLNDHCVAELSLFLGDLLSLNLGNCRLLTVSTFFALITNCPSL 391
+ S+S+ I +++ ++D+ V L+ LL C+ L+ ++ A+ ++CP L
Sbjct: 50 IASRSQNIIEINISDCRSMSDNGVCVLAFKCPGLLRYTAYRCKQLSDTSIIAVASHCPLL 109
Query: 392 TEI---NMNRTNIQGTTIPNSLMDRLVNPQFKSLFLASAACLEDQNIIMFAALFPNLQQL 448
++ N ++ +G S L K + + D+ +I+ A LQ++
Sbjct: 110 QKVHVGNQDKLTDEGLKQLGSKCREL-----KDIHFGQCYKISDEGMIVIAKGCLKLQRI 164
Query: 449 HLSCSYNITEEGIRPLLESCRKIRHLNLTCLSLKSLGTNF--DLPDLEVLNLTN-TEVDD 505
++ + +T++ ++ E C +++++ S+ S G L +L L+L + TE+D+
Sbjct: 165 YMQENKLVTDQSVKAFAEHCPELQYVGFMGCSVTSKGVIHLTKLRNLSSLDLRHITELDN 224
Query: 506 EALYIISNRCPALLQLVLLRCDYITDKGVMHVVNNCTQLREINLDGCPNVQAKVVA 561
E + I RC L L L I D+ V + L+E+ L C ++A
Sbjct: 225 ETVMEIVKRCKNLSSLNLCLNWIINDRCVEVIAKEGQNLKELYLVSCKITDYALIA 280
Score = 57.0 bits (136), Expect = 1e-07
Identities = 51/259 (19%), Positives = 107/259 (40%), Gaps = 35/259 (13%)
Query: 340 QHLDLQYTDFLNDHCVAELSLFLGDLLSLNLGNCRLLTVSTFFALITNCPSLTEINMNRT 399
+ LDL + D + +++ +++ +N+ +CR ++ + L CP L R
Sbjct: 32 KQLDLSSRQQVTDELLEKIASRSQNIIEINISDCRSMSDNGVCVLAFKCPGLLRYTAYR- 90
Query: 400 NIQGTTIPNSLMDRLVNPQFKSLFLASAACLEDQNIIMFAALFPNLQQLHLSCSYNITEE 459
L D +II A+ P LQ++H+ +T+E
Sbjct: 91 ---------------------------CKQLSDTSIIAVASHCPLLQKVHVGNQDKLTDE 123
Query: 460 GIRPLLESCRKIRHLNL-TCLSLKSLG----TNFDLPDLEVLNLTNTEVDDEALYIISNR 514
G++ L CR+++ ++ C + G L + N V D+++ +
Sbjct: 124 GLKQLGSKCRELKDIHFGQCYKISDEGMIVIAKGCLKLQRIYMQENKLVTDQSVKAFAEH 183
Query: 515 CPALLQLVLLRCDYITDKGVMHVVNNCTQLREINLDGCPNVQAKVVASMVVSRPSLRKIH 574
CP L + + C +T KGV+H + L ++L + + V +V +L ++
Sbjct: 184 CPELQYVGFMGCS-VTSKGVIH-LTKLRNLSSLDLRHITELDNETVMEIVKRCKNLSSLN 241
Query: 575 VPPNFPLSDRNRKLFSRHG 593
+ N+ ++DR ++ ++ G
Sbjct: 242 LCLNWIINDRCVEVIAKEG 260
Score = 42.7 bits (99), Expect = 0.003
Identities = 57/301 (18%), Positives = 118/301 (38%), Gaps = 40/301 (13%)
Query: 97 LDLSYYYGDLDALLTQISSFPMLKLTSLNLSNQLILPANGLRAFSQNITTLTSLICSNLI 156
LDLS D LL +I+S + +N+S+ + NG+ + L
Sbjct: 34 LDLSSRQQVTDELLEKIASRSQ-NIIEINISDCRSMSDNGVCVLAFKCPGLLRYTAYRCK 92
Query: 157 SLNSTDIHLIADTFPLLEELDLAYPSKIINH-------------------THATFSTGLE 197
L+ T I +A PLL+++ + K+ + + G+
Sbjct: 93 QLSDTSIIAVASHCPLLQKVHVGNQDKLTDEGLKQLGSKCRELKDIHFGQCYKISDEGMI 152
Query: 198 ALSLALIKLRKVNLSYHGYLNGTLLSHLFKNCKFLQEVILLRCEQLT-----------IA 246
++ +KL+++ + + + + ++C LQ V + C + ++
Sbjct: 153 VIAKGCLKLQRIYMQENKLVTDQSVKAFAEHCPELQYVGFMGCSVTSKGVIHLTKLRNLS 212
Query: 247 GVDL---ALLQKPTLTSLSITCTVTTGLEHLTSHFIDS----LLSLKG--LTSLLLTGFR 297
+DL L T+ + C + L + I+ +++ +G L L L +
Sbjct: 213 SLDLRHITELDNETVMEIVKRCKNLSSLNLCLNWIINDRCVEVIAKEGQNLKELYLVSCK 272
Query: 298 ISDQFLSSIAMESLPLRRLVLSYCPGYTYSGISFLLSKSKRIQHLDLQYTDFLNDHCVAE 357
I+D L +I S+ + + + +C T G + + SK +++L L D +N+ V +
Sbjct: 273 ITDYALIAIGRYSMTIETVDVGWCKEITDQGATLIAQSSKSLRYLGLMRCDKVNEVTVEQ 332
Query: 358 L 358
L
Sbjct: 333 L 333
Score = 36.6 bits (83), Expect = 0.19
Identities = 45/250 (18%), Positives = 106/250 (42%), Gaps = 16/250 (6%)
Query: 297 RISDQFLSSIAMESLPLRRLVLSYCPGYTYSGISFLLSKSKRIQHLDLQYTDFLNDHCVA 356
++SD + ++A L+++ + T G+ L SK + ++ + ++D +
Sbjct: 93 QLSDTSIIAVASHCPLLQKVHVGNQDKLTDEGLKQLGSKCRELKDIHFGQCYKISDEGMI 152
Query: 357 ELSLFLGDLLSLNLGNCRLLTVSTFFALITNCPSLTEINMNRTNIQGTTIPNSLMDRLVN 416
++ L + + +L+T + A +CP L + ++ + + + +L N
Sbjct: 153 VIAKGCLKLQRIYMQENKLVTDQSVKAFAEHCPELQYVGFMGCSVTSKGVIH--LTKLRN 210
Query: 417 PQFKSLFLASAACLEDQNIIMFAALFPNLQQLHLSCSYNITEEGIRPLLESCRKIRHLNL 476
SL L L+++ ++ NL L+L ++ I + + + + + ++ L L
Sbjct: 211 --LSSLDLRHITELDNETVMEIVKRCKNLSSLNLCLNWIINDRCVEVIAKEGQNLKELYL 268
Query: 477 TCLSLKSLGTNFDLPDLEVLNLTNTEVD--------DEALYIISNRCPALLQLVLLRCDY 528
+ T++ L + ++T VD D+ +I+ +L L L+RCD
Sbjct: 269 VSCKI----TDYALIAIGRYSMTIETVDVGWCKEITDQGATLIAQSSKSLRYLGLMRCDK 324
Query: 529 ITDKGVMHVV 538
+ + V +V
Sbjct: 325 VNEVTVEQLV 334
>FXLG_HUMAN (Q8N461) F-box/LRR-repeat protein 16 (F-box and
leucine-rich repeat protein 16) (cg14134)
Length = 479
Score = 55.5 bits (132), Expect = 4e-07
Identities = 71/293 (24%), Positives = 124/293 (42%), Gaps = 38/293 (12%)
Query: 278 FIDSL-LSLKGLTSLLLTGFRISDQFLSSIAMESLPLRRLVLSYCPGYTYSGISFLLSKS 336
FID+ LS KG+ ++ L I+D L + + + RL LS C +T +G+ S S
Sbjct: 184 FIDNYALSKKGVKAMSLKRSTITDAGLEVMLEQMQGVVRLELSGCNDFTEAGL--WSSLS 241
Query: 337 KRIQHLDLQYTDFLNDHCVAELSLFLGDLLSLNLGNCRLLTVSTFFALITNCPSLTEINM 396
RI L + + D +A +S L P+L E+++
Sbjct: 242 ARITSLSVSDCINVADDAIAAISQLL--------------------------PNLAELSL 275
Query: 397 NRTNIQGTTIPNSLMDRLVNPQFKSLFLASAACLEDQNIIMFAALFPNLQQLHLSCSYNI 456
++ T + + +L L S + + ++ PNL L LS +
Sbjct: 276 QAYHVTDTAL--AYFTARQGHSTHTLRLLSCWEITNHGVVNVVHSLPNLTALSLSGCSKV 333
Query: 457 TEEGIRPLLESCRKIRHLNLT-CLSLKSLGTNF---DLPDLEVLNLTN-TEVDDEALYII 511
T++G+ + E+ RK+R L+L+ C + + + DL LE L L + D L +
Sbjct: 334 TDDGVELVAENLRKLRSLDLSWCPRITDMALEYVACDLHRLEELVLDRCVRITDTGLSYL 393
Query: 512 SNRCPALLQLVLLRCDYITDKGVMHVVNNCTQLREINLDGCPNVQAKVVASMV 564
S +L L L C + D G+ H++ LR ++ GCP + ++ +V
Sbjct: 394 ST-MSSLRSLYLRWCCQVQDFGLKHLL-ALGSLRLLSPAGCPLLTTTGLSGLV 444
Score = 52.0 bits (123), Expect = 4e-06
Identities = 58/209 (27%), Positives = 96/209 (45%), Gaps = 19/209 (9%)
Query: 196 LEALSLALIKLRKVNLSYHGYLNGTLLSHLFKNCKFLQEVILLRCEQLTIAGVDLALLQK 255
+ A+S L L +++L + + L + + LL C ++T GV +
Sbjct: 260 IAAISQLLPNLAELSLQAYHVTDTALAYFTARQGHSTHTLRLLSCWEITNHGVVNVVHSL 319
Query: 256 PTLTSLSITCTVTTGLEHLTSHFIDSLL-SLKGLTSLLLTGF-RISDQFLSSIAMESLPL 313
P LT+LS++ G +T ++ + +L+ L SL L+ RI+D L +A + L
Sbjct: 320 PNLTALSLS-----GCSKVTDDGVELVAENLRKLRSLDLSWCPRITDMALEYVACDLHRL 374
Query: 314 RRLVLSYCPGYTYSGISFLLSKSKRIQHLDLQYTDFLNDHCVAELSLFLGDLLSLNLGNC 373
LVL C T +G+S+L + S ++ L L++ + D + L L LG L L+ C
Sbjct: 375 EELVLDRCVRITDTGLSYLSTMSS-LRSLYLRWCCQVQDFGLKHL-LALGSLRLLSPAGC 432
Query: 374 RLLTVSTFFALI----------TNCPSLT 392
LLT + L+ TNCP T
Sbjct: 433 PLLTTTGLSGLVQLQELEELELTNCPGAT 461
Score = 43.1 bits (100), Expect = 0.002
Identities = 40/167 (23%), Positives = 77/167 (45%), Gaps = 8/167 (4%)
Query: 415 VNPQFKSLFLASAACLEDQNIIMFAALFPNLQQLHLSCSYNITEEGIRPLLESCRKIRHL 474
++ + SL ++ + D I + L PNL +L L +Y++T+ + H
Sbjct: 240 LSARITSLSVSDCINVADDAIAAISQLLPNLAELSLQ-AYHVTDTALAYFTARQGHSTHT 298
Query: 475 N--LTCLSLKSLGTN---FDLPDLEVLNLTN-TEVDDEALYIISNRCPALLQLVLLRCDY 528
L+C + + G LP+L L+L+ ++V D+ + +++ L L L C
Sbjct: 299 LRLLSCWEITNHGVVNVVHSLPNLTALSLSGCSKVTDDGVELVAENLRKLRSLDLSWCPR 358
Query: 529 ITDKGVMHVVNNCTQLREINLDGCPNVQAKVVASMVVSRPSLRKIHV 575
ITD + +V + +L E+ LD C + S + + SLR +++
Sbjct: 359 ITDMALEYVACDLHRLEELVLDRCVRI-TDTGLSYLSTMSSLRSLYL 404
Score = 42.0 bits (97), Expect = 0.005
Identities = 60/242 (24%), Positives = 104/242 (42%), Gaps = 23/242 (9%)
Query: 87 LLQRFTKLTSLDLSYYYGDLDALLTQI-SSFPMLKLTSLNLSNQLILPANGLRAFSQNIT 145
L R T L+ D D A ++Q+ + L L + ++++ + + S +
Sbjct: 240 LSARITSLSVSDCINVADDAIAAISQLLPNLAELSLQAYHVTDTALAYFTARQGHSTH-- 297
Query: 146 TLTSLICSNLISLNSTDIHLIADTFPLLEELDLAYPSKIINHTHATFSTGLEALSLALIK 205
TL L C + + ++ + P L L L+ SK+ + G+E ++ L K
Sbjct: 298 TLRLLSCWEITNHGVVNV---VHSLPNLTALSLSGCSKVTDD-------GVELVAENLRK 347
Query: 206 LRKVNLSYHGYLNGTLLSHLFKNCKFLQEVILLRCEQLTIAGVD-LALLQKPTLTSLSIT 264
LR ++LS+ + L ++ + L+E++L RC ++T G+ L+ + L
Sbjct: 348 LRSLDLSWCPRITDMALEYVACDLHRLEELVLDRCVRITDTGLSYLSTMSSLRSLYLRWC 407
Query: 265 CTVTT-GLEHLTSHFIDSLLSLKGLTSLLLTGFRISDQFLSSIAMESLPLRRLVLSYCPG 323
C V GL+HL + LLS G L TG S ++ L L L+ CPG
Sbjct: 408 CQVQDFGLKHLLALGSLRLLSPAGCPLLTTTGL--------SGLVQLQELEELELTNCPG 459
Query: 324 YT 325
T
Sbjct: 460 AT 461
Score = 40.8 bits (94), Expect = 0.010
Identities = 33/173 (19%), Positives = 77/173 (44%), Gaps = 9/173 (5%)
Query: 390 SLTEINMNRTNIQGTTIPNSLMDRLVNPQFKSLFLASAACLEDQNIIMFAALFPNLQQLH 449
+L++ + +++ +TI ++ ++ ++ + L + C + ++++L + L
Sbjct: 189 ALSKKGVKAMSLKRSTITDAGLEVMLEQMQGVVRLELSGCNDFTEAGLWSSLSARITSLS 248
Query: 450 LSCSYNITEEGIRPLLESCRKIRHLNL-------TCLSLKSLGTNFDLPDLEVLNLTNTE 502
+S N+ ++ I + + + L+L T L+ + L +L+ E
Sbjct: 249 VSDCINVADDAIAAISQLLPNLAELSLQAYHVTDTALAYFTARQGHSTHTLRLLSCW--E 306
Query: 503 VDDEALYIISNRCPALLQLVLLRCDYITDKGVMHVVNNCTQLREINLDGCPNV 555
+ + + + + P L L L C +TD GV V N +LR ++L CP +
Sbjct: 307 ITNHGVVNVVHSLPNLTALSLSGCSKVTDDGVELVAENLRKLRSLDLSWCPRI 359
>SKP2_HUMAN (Q13309) S-phase kinase-associated protein 2 (F-box
protein Skp2) (Cyclin A/CDK2-associated protein p45)
(p45skp2) (F-box/LRR-repeat protein 1)
Length = 424
Score = 49.7 bits (117), Expect = 2e-05
Identities = 35/112 (31%), Positives = 56/112 (49%), Gaps = 3/112 (2%)
Query: 288 LTSLLLTGFRISDQFLSSIAMESLPLRRLVLSYCPGYTYSGISFLLSKSKRIQHLDLQYT 347
L +L L G R+SD ++++A S L RL LS C G++ + LLS R+ L+L +
Sbjct: 208 LQNLSLEGLRLSDPIVNTLAKNS-NLVRLNLSGCSGFSEFALQTLLSSCSRLDELNLSWC 266
Query: 348 -DFLNDHCVAELSLFLGDLLSLNLGNCRL-LTVSTFFALITNCPSLTEINMN 397
DF H ++ + LNL R L S L+ CP+L ++++
Sbjct: 267 FDFTEKHVQVAVAHVSETITQLNLSGYRKNLQKSDLSTLVRRCPNLVHLDLS 318
>SKP2_MOUSE (Q9Z0Z3) S-phase kinase-associated protein 2 (F-box
protein Skp2) (Cyclin A/CDK2-associated protein p45)
(F-box/WD-40 protein 1) (FWD1)
Length = 424
Score = 48.1 bits (113), Expect = 6e-05
Identities = 33/112 (29%), Positives = 56/112 (49%), Gaps = 3/112 (2%)
Query: 288 LTSLLLTGFRISDQFLSSIAMESLPLRRLVLSYCPGYTYSGISFLLSKSKRIQHLDLQYT 347
L +L L G ++SD + ++A L RL L C G++ S ++ LLS R+ L+L +
Sbjct: 208 LQNLSLEGLQLSDPIVKTLAQNE-NLVRLNLCGCSGFSESAVATLLSSCSRLDELNLSWC 266
Query: 348 -DFLNDHCVAELSLFLGDLLSLNLGNCRL-LTVSTFFALITNCPSLTEINMN 397
DF H A ++ + LNL R L + +I CP+L ++++
Sbjct: 267 FDFTEKHVQAAVAHLPNTITQLNLSGYRKNLQKTDLCTIIKRCPNLIRLDLS 318
Score = 33.1 bits (74), Expect = 2.1
Identities = 43/199 (21%), Positives = 88/199 (43%), Gaps = 27/199 (13%)
Query: 396 MNRTNIQGTTIPNSLMDRLVNPQFKSLFL-----ASAACLEDQNIIMFAALFPNL----Q 446
++R N G + +SL D L+ F L L S C + + +L+ +L +
Sbjct: 87 LSRENFPGVSW-DSLPDELLLGIFSCLCLPELLRVSGVCKRWYRLSLDESLWQSLDLAGK 145
Query: 447 QLHLSCSYNITEEGI-----------RPLLESCR--KIRHLNLTCLSLKSLGTNFDLPD- 492
LH + + G+ +PL ES +++H++L+ + + L +
Sbjct: 146 NLHPDVTVRLLSRGVVAFRCPRSFMEQPLGESFSSFRVQHMDLSNSVINVSNLHKILSEC 205
Query: 493 --LEVLNLTNTEVDDEALYIISNRCPALLQLVLLRCDYITDKGVMHVVNNCTQLREINLD 550
L+ L+L ++ D + ++ L++L L C ++ V ++++C++L E+NL
Sbjct: 206 SKLQNLSLEGLQLSDPIVKTLAQN-ENLVRLNLCGCSGFSESAVATLLSSCSRLDELNLS 264
Query: 551 GCPNVQAKVVASMVVSRPS 569
C + K V + V P+
Sbjct: 265 WCFDFTEKHVQAAVAHLPN 283
>SHO2_MOUSE (O88520) Leucine-rich repeat protein SHOC-2 (Ras-binding
protein Sur-8)
Length = 582
Score = 45.8 bits (107), Expect = 3e-04
Identities = 57/223 (25%), Positives = 101/223 (44%), Gaps = 38/223 (17%)
Query: 338 RIQHLDLQYTDFLNDHCVAELSLFLGDLLSLNLGNCRLLTVSTFFALITNCPSLTEINMN 397
+I +LDLQ+ D L +L +G+L SLN R +S + C +L E+N+
Sbjct: 262 QITNLDLQHNDLL------DLPDTIGNLSSLNRLGLRYNRLSAIPRSLAKCSALEELNLE 315
Query: 398 RTNIQGTTIPNSLMDRLVNPQFKSLFLASAACLEDQNIIMFAALFPNLQQLHLSCSYNIT 457
NI +T+P SL+ LV + SL LA C + L+P S Y++
Sbjct: 316 NNNI--STLPESLLSSLV--KLNSLTLA-RNCFQ---------LYPVGGPSQFSTIYSLN 361
Query: 458 EEGIR------PLLESCRKIRHLNLTCLSLKSL----GTNFDLPDLEVLNLTNTEVDDEA 507
E R + + + LN+ L SL GT + +L + T++ ++
Sbjct: 362 MEHNRINKIPFGIFSRAKVLSKLNMKDNQLTSLPLDFGTWTSMVELNLATNQLTKIPEDV 421
Query: 508 LYIISNRCPALLQLVLLRCDYITDKGVMHVVNNCTQLREINLD 550
++S L++++L + + K + H + N +LRE++L+
Sbjct: 422 SGLVS------LEVLILSNNLL--KKLPHGLGNLRKLRELDLE 456
Database: sprot
Posted date: Nov 25, 2004 10:54 AM
Number of letters in database: 59,974,054
Number of sequences in database: 164,201
Lambda K H
0.323 0.138 0.400
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 64,021,829
Number of Sequences: 164201
Number of extensions: 2520189
Number of successful extensions: 6535
Number of sequences better than 10.0: 81
Number of HSP's better than 10.0 without gapping: 24
Number of HSP's successfully gapped in prelim test: 58
Number of HSP's that attempted gapping in prelim test: 6140
Number of HSP's gapped (non-prelim): 248
length of query: 598
length of database: 59,974,054
effective HSP length: 116
effective length of query: 482
effective length of database: 40,926,738
effective search space: 19726687716
effective search space used: 19726687716
T: 11
A: 40
X1: 16 ( 7.5 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (22.0 bits)
S2: 69 (31.2 bits)
Medicago: description of AC140915.5