BLAST2 result
BLASTP 2.2.2 [Dec-14-2001]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= AC140913.13 + phase: 0 /pseudo
(676 letters)
Database: sprot
164,201 sequences; 59,974,054 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
IFA2_CAEEL (O02365) Intermediate filament protein ifa-2 (Interme... 63 2e-09
IFA3_CAEEL (Q21065) Intermediate filament protein ifa-3 (Interme... 63 3e-09
MYSS_CYPCA (Q90339) Myosin heavy chain, fast skeletal muscle 59 5e-08
MYSN_DROME (Q99323) Myosin heavy chain, non-muscle (Zipper prote... 58 9e-08
MYHB_CHICK (P10587) Myosin heavy chain, gizzard smooth muscle 58 9e-08
MYHA_HUMAN (P35580) Myosin heavy chain, nonmuscle type B (Cellul... 57 1e-07
MYH9_HUMAN (P35579) Myosin heavy chain, nonmuscle type A (Cellul... 56 3e-07
TAXB_CHICK (Q9I969) Beta-taxilin (Muscle derived protein 77) 56 4e-07
MYSB_CAEEL (P02566) Myosin heavy chain B (MHC B) 56 4e-07
MYHB_RABIT (P35748) Myosin heavy chain, smooth muscle isoform (S... 55 5e-07
EEA1_HUMAN (Q15075) Early endosome antigen 1 (Endosome-associate... 55 5e-07
MYHA_BOVIN (Q27991) Myosin heavy chain, nonmuscle type B (Cellul... 55 8e-07
USO1_YEAST (P25386) Intracellular protein transport protein USO1 54 1e-06
MYHB_HUMAN (P35749) Myosin heavy chain, smooth muscle isoform (S... 54 1e-06
MYHA_RAT (Q9JLT0) Myosin heavy chain, nonmuscle type B (Cellular... 54 2e-06
MYH3_HUMAN (P11055) Myosin heavy chain, fast skeletal muscle, em... 54 2e-06
CING_XENLA (Q9PTD7) Cingulin 54 2e-06
MYH9_RAT (Q62812) Myosin heavy chain, nonmuscle type A (Cellular... 53 2e-06
TRHY_RABIT (P37709) Trichohyalin 53 3e-06
MYSP_BOOMI (Q86RN8) Paramyosin 53 3e-06
>IFA2_CAEEL (O02365) Intermediate filament protein ifa-2
(Intermediate filament protein A2) (IF-A2) (Cel IF A2)
Length = 581
Score = 63.2 bits (152), Expect = 2e-09
Identities = 51/199 (25%), Positives = 88/199 (43%), Gaps = 24/199 (12%)
Query: 44 KGRIGEPHYSLKT--STELLKVLNRIWSLEEQHSSNISLIKALKTELDRTRIKVKELLRD 101
+GR G+ S+K E+ N + + H I+ L+ +LD R K +E R
Sbjct: 107 QGRFGKSTGSVKVMYEMEITTATNVVKQTGKDHGETEKEIRKLQDQLDELRKKFEEAQRG 166
Query: 102 RQADRHEVDDLMKQIA----------------EDKLVRKSKEQDRLHAAVQSVRDELEDE 145
R DR ++DDL+ ++ E+++ R KE RL + +Q VR EL+ E
Sbjct: 167 RAEDRLKIDDLLVTLSNLEAEINLLKRRIALLEEEVARLKKENFRLTSELQRVRIELDQE 226
Query: 146 RKLRKRSESIHRKLARELSEMKSSFTSALKDLEQERTRRKLLED---LCDEFARGINEYE 202
LR +++ + + E+ MK F + LK+L+ + R E+ +E A + +
Sbjct: 227 TLLRIDNQNKVKTILEEIDFMKRGFETELKELQAQAARDTTSENREYFKNELANAMRDIR 286
Query: 203 QEVHTLKQKSEKD---WVQ 218
E + + D W Q
Sbjct: 287 AEYDQIMNGNRNDMESWYQ 305
>IFA3_CAEEL (Q21065) Intermediate filament protein ifa-3
(Intermediate filament protein A3) (IF-A3) (Cel IF A3)
Length = 581
Score = 62.8 bits (151), Expect = 3e-09
Identities = 69/288 (23%), Positives = 120/288 (40%), Gaps = 39/288 (13%)
Query: 44 KGRIGEPHYSLKT--STELLKVLNRIWSLEEQHSSNISLIKALKTELDRTRIKVKELLRD 101
+ R G+ S+K E+ N + + H I +K +LD R K +E +
Sbjct: 107 QSRFGKSTGSVKIMYEMEITTATNVVKETGKDHEEAEKEIGKIKDQLDELRKKFEEAQKG 166
Query: 102 RQADRHEVDDLMKQIA----------------EDKLVRKSKEQDRLHAAVQSVRDELEDE 145
R DR ++D+L+ ++ E+++ R KE RL + +Q VR EL+ E
Sbjct: 167 RAEDRLKIDELLVTLSNLEAEINLLKRRIALLEEEVARLKKENFRLTSELQRVRSELDQE 226
Query: 146 RKLRKRSESIHRKLARELSEMKSSFTSALKDLEQERTRRKLLEDLCDEFARGINEYEQEV 205
LR +++ + E+ MK F + LKDL+ + R E+ E+ + NE +
Sbjct: 227 TLLRIDNQNKVTTILEEIDFMKRGFETELKDLQAQAARDTTSEN--REYFK--NELMNSI 282
Query: 206 HTLKQKSEKDWVQRADHDRLVL---HISESWLDERMQ---MQLEAAQNGFMDKNSIVDKL 259
+ RA++DR + + ESW R+Q Q K V +L
Sbjct: 283 RDI----------RAEYDRFMAGNRNDLESWSQIRVQEINTQTNRQNAEINHKRDEVKRL 332
Query: 260 SLEIETFIKAKQNSRSAENQVIRDRRNSLESVPLNDAVSAPQAMGDDD 307
++ +K+K +A N ++ + L +D S A+ D D
Sbjct: 333 HSQVSE-LKSKHAELAARNGLLEKQLEDLNYQLEDDQRSYEAALNDKD 379
>MYSS_CYPCA (Q90339) Myosin heavy chain, fast skeletal muscle
Length = 1935
Score = 58.5 bits (140), Expect = 5e-08
Identities = 82/370 (22%), Positives = 154/370 (41%), Gaps = 31/370 (8%)
Query: 64 LNRIWSLEEQHSSNISLIKALKTELDRTRIKVKELLRDRQADRHEVDDLMKQI--AEDKL 121
+ R LEE ++ + ++ K L + +Q + EV+DLM + A
Sbjct: 1381 IQRTEELEEAKKKLAQRLQDAEESIEAVNSKCASLEKTKQRLQGEVEDLMIDVERANSLA 1440
Query: 122 VRKSKEQDRLHAAVQSVRDELEDERKLRKRSESIHRKLARELSEMKSSFTSALKDLEQER 181
K+Q + + + E+ + + ++ R L+ EL +MK+S+ AL LE +
Sbjct: 1441 ANLDKKQRNFDKVLAEWKQKYEESQAELEGAQKEARSLSTELFKMKNSYEEALDHLETLK 1500
Query: 182 TRRKLLEDLCDEFARGINEYEQEVHTLKQ-----KSEKDWVQRA-DHDRLVLHISESWLD 235
K L+ + + E + +H L++ +SEK +Q A + L ES +
Sbjct: 1501 RENKNLQQEISDLTEQLGETGKSIHELEKAKKTVESEKSEIQTALEEAEGTLEHEESKI- 1559
Query: 236 ERMQMQLEAAQNGFMDKNSIVDKLSLEIETFIKAKQNSRSAENQVIRDRRNSLESV--PL 293
+++QLE Q K+ I KL+ + E + K+NS+ +VI +++L+S
Sbjct: 1560 --LRVQLELNQ----VKSEIDRKLAEKDEEMEQIKRNSQ----RVIDSMQSTLDSEVRSR 1609
Query: 294 NDAVSAPQAMGDDDDDDSVGSDSHCFELNKPSHMGAKVHKEEILDKNLDETSKSNVKKKK 353
NDA+ + M D ++ + +L+ + A+ K+ L + + + +
Sbjct: 1610 NDALRVKKKMEGDLNEMEI-------QLSHANRQAAEAQKQ--LRNVQGQLKDAQLHLDE 1660
Query: 354 SVPG-EGFKNHIPSNSNKKSQSVDAEEGLTTNIRLVEGTRISEEPEHFEISESGGFERKN 412
+V G E K + + S E L + E R E E + SE G
Sbjct: 1661 AVRGQEDMKEQVAMVERRNSLMQAEIEELRAALEQTERGRKVAEQELVDASERVGLLHSQ 1720
Query: 413 NLSELHSTSK 422
N S +++ K
Sbjct: 1721 NTSLINTKKK 1730
Score = 48.5 bits (114), Expect = 6e-05
Identities = 51/186 (27%), Positives = 86/186 (45%), Gaps = 28/186 (15%)
Query: 71 EEQHSSNISLIKALKTELDRTRIKVKELLRDRQA--DRHE--VDDLMKQIAEDKLVRKSK 126
+E+H++ + +K L E+ + +L ++++A + H+ +DDL Q EDK+ +K
Sbjct: 967 KEKHATE-NKVKNLTEEMASQDESIAKLTKEKKALQEAHQQTLDDL--QAEEDKVNTLTK 1023
Query: 127 EQDRLHAAVQSVRDELEDERKLRKRSESIHRKLARELSEMKSSFTSALKDLEQ--ERTRR 184
+ +L V + LE E+KLR E RKL +L + S + +Q E+ ++
Sbjct: 1024 AKTKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESIMDLENEKQQSDEKIKK 1083
Query: 185 K------LLEDLCDEFARG-------------INEYEQEVHTLKQKSEKDWVQRADHDRL 225
K LL + DE + G I E E+E+ + K QRAD R
Sbjct: 1084 KDFEISQLLSKIEDEQSLGAQLQKKIKELQARIEELEEEIEAERAARAKVEKQRADLSRE 1143
Query: 226 VLHISE 231
+ ISE
Sbjct: 1144 LEEISE 1149
Score = 44.7 bits (104), Expect = 8e-04
Identities = 64/276 (23%), Positives = 110/276 (39%), Gaps = 49/276 (17%)
Query: 57 STELLKVLNRIWSLEEQHSSNISLIKALKTELDRTRIKVKE----------LLRDRQADR 106
S EL ++ R+ ++ I + K + E + R ++E LR QAD
Sbjct: 1141 SRELEEISERLEEAGGATAAQIEMNKKREAEFQKMRRDLEESTLQHEATAAALRKEQAD- 1199
Query: 107 HEVDDLMKQIAEDKLVRKS--KEQDRLHAAVQSVRDELEDERKLRKRSESIHRKLARELS 164
V +L +QI + V++ KE+ + + +E K + E + R L +LS
Sbjct: 1200 -SVAELGEQIDNLQRVKQKLEKEKSEYKMEIDDLTSNMEAVAKAKANLEKMCRTLEDQLS 1258
Query: 165 EMKSSFTSALKDLEQERTRRKLLEDLCDEFARGINE--------------YEQEVHTLKQ 210
E+K+ ++ L +R L+ EF+R + E Y Q++ LK+
Sbjct: 1259 EIKTKSDENVRQLNDMNAQRARLQTENGEFSRQLEEKEALVSQLTRGKQAYTQQIEELKR 1318
Query: 211 KSEKD---------WVQRADHDRLVLHISESWLDERMQMQLEAAQNGFMDKNSIVDKLSL 261
E++ VQ A HD + +E + + E Q G NS V +
Sbjct: 1319 HIEEEVKAKNALAHAVQSARHD---CDLLREQYEEEQEAKAE-LQRGMSKANSEVAQWRT 1374
Query: 262 EIETFIKAKQNSRSAEN------QVIRDRRNSLESV 291
+ ET A Q + E Q ++D S+E+V
Sbjct: 1375 KYET--DAIQRTEELEEAKKKLAQRLQDAEESIEAV 1408
Score = 43.9 bits (102), Expect = 0.001
Identities = 49/248 (19%), Positives = 104/248 (41%), Gaps = 33/248 (13%)
Query: 69 SLEEQHSSNISLIKA---LKTELDRTRIKVKELLRDRQADRH-------EVDDLMKQIAE 118
SLE++ + L +A L+ +L + + +L ++Q E+ L+ +I +
Sbjct: 1038 SLEQEKKLRMDLERAKRKLEGDLKLAQESIMDLENEKQQSDEKIKKKDFEISQLLSKIED 1097
Query: 119 DKLV--RKSKEQDRLHAAVQSVRDELEDERKLRKRSESIHRKLARELSEMKSSFTSA--- 173
++ + + K+ L A ++ + +E+E ER R + E L+REL E+ A
Sbjct: 1098 EQSLGAQLQKKIKELQARIEELEEEIEAERAARAKVEKQRADLSRELEEISERLEEAGGA 1157
Query: 174 -LKDLEQERTRRKLLEDLCDEFARGINEYEQEVHTLKQKSEKDWVQRADHDRLVLHISES 232
+E + R + + + ++E L+++ + + + + +
Sbjct: 1158 TAAQIEMNKKREAEFQKMRRDLEESTLQHEATAAALRKEQADSVAELGEQIDNLQRVKQK 1217
Query: 233 WLDERMQMQLEAAQNGFMDKNSIVDKLSLEIETFIKAKQN----SRSAENQVIRDRRNSL 288
E+ + ++E +D L+ +E KAK N R+ E+Q+ + S
Sbjct: 1218 LEKEKSEYKME------------IDDLTSNMEAVAKAKANLEKMCRTLEDQLSEIKTKSD 1265
Query: 289 ESV-PLND 295
E+V LND
Sbjct: 1266 ENVRQLND 1273
Score = 41.6 bits (96), Expect = 0.007
Identities = 56/246 (22%), Positives = 102/246 (40%), Gaps = 30/246 (12%)
Query: 61 LKVLNRIWSLEEQHSSNISLIKALKTELDRTRIKVKELLRDRQADRHEVDDLMKQI---- 116
+K L + E++ ++ + +K +L + K KEL + E +DL Q+
Sbjct: 837 IKPLLKSAETEKEMAAMKENYEKMKEDLTKALAKKKELEEKMVSLLQEKNDLQLQVTAES 896
Query: 117 -----AEDKLVRKSKEQDRLHAAVQSVRDELEDERKLRKRSESIHRKLARELSEMKS--- 168
AE++ K + +L A ++ + LEDE ++ + RKL E SE+K
Sbjct: 897 ENLSDAEERCEGLIKSKIQLEAKLKETNERLEDEEEINAELTAKKRKLEDECSELKKDID 956
Query: 169 --SFTSALKDLEQERTRRKLLEDLCDEFARGINEYEQEVHTLKQKSEKDWVQRADHDRL- 225
T A + E+ T K +++L +E A Q+ K EK +Q A L
Sbjct: 957 DLELTLAKVEKEKHATENK-VKNLTEEMA------SQDESIAKLTKEKKALQEAHQQTLD 1009
Query: 226 VLHISESWLDERMQMQLEAAQNGFMDKNSIVDKLSLEIETFIKAKQNSRSAENQVIRDRR 285
L E ++ + + + Q VD L +E K + + A+ ++ D +
Sbjct: 1010 DLQAEEDKVNTLTKAKTKLEQQ--------VDDLEGSLEQEKKLRMDLERAKRKLEGDLK 1061
Query: 286 NSLESV 291
+ ES+
Sbjct: 1062 LAQESI 1067
Score = 37.4 bits (85), Expect = 0.13
Identities = 51/227 (22%), Positives = 104/227 (45%), Gaps = 20/227 (8%)
Query: 75 SSNISLIKALKTELDRTRIKVKELLRDRQADRHEVDDLMKQI--AEDKLVRKSKEQDRLH 132
S + L+ + T L T+ K+L D + EVDD +++ AE+K + + +
Sbjct: 1711 SERVGLLHSQNTSLINTK---KKLEADLVQVQGEVDDAVQEARNAEEKAKKAITDAAMMA 1767
Query: 133 AAVQSVRDELEDERKLRKRSESIHRKLARELSEMKS-SFTSALKDLEQERTRRKLLEDLC 191
++ +D +++K E + L L E +S + K L++ +R + LE
Sbjct: 1768 EELKKEQDTSAHLERMKKNLEVTVKDLQHRLDEAESLAMKGGKKQLQKLESRVRELEAEV 1827
Query: 192 D-------EFARGINEYEQEVHTLKQKSEKDWVQRADHDRLVLHISESWLDERM-QMQLE 243
+ + +G+ +YE+ V L ++E+D + + RL + + L ++ + Q E
Sbjct: 1828 EAEQRRGADAVKGVRKYERRVKELTYQTEED---KKNVIRLQDLVDKLQLKVKVYKRQAE 1884
Query: 244 AAQNGFMDKNSIVDKLSLEIETFIKAKQNSRSAENQVIRDRRNSLES 290
A+ S K+ E+E +A++ + AE+QV + R S ++
Sbjct: 1885 EAEEQTNTHLSRYRKVQHELE---EAQERADVAESQVNKLRAKSRDA 1928
>MYSN_DROME (Q99323) Myosin heavy chain, non-muscle (Zipper protein)
(Myosin II) (Non-muscle MHC)
Length = 2057
Score = 57.8 bits (138), Expect = 9e-08
Identities = 76/370 (20%), Positives = 152/370 (40%), Gaps = 39/370 (10%)
Query: 62 KVLNR-IWSLEEQHSSNISLIKALKTELDRTRIKVKELLRDRQADRHEVDDLMKQIAEDK 120
K LN+ I +LE Q + + A LD+++ K++ L D E++ ++ E
Sbjct: 1479 KRLNKDIEALERQ----VKELIAQNDRLDKSKKKIQSELEDATI---ELEAQRTKVLE-- 1529
Query: 121 LVRKSKEQDRLHAAVQSVRDELEDERKLRKRSESIHRKLARELSEMKSSFTSALKDLEQE 180
L +K K D++ A +++ +++ ER +R +S ++DLE +
Sbjct: 1530 LEKKQKNFDKILAEEKAISEQIAQERDTAEREAREKETKVLSVSRELDEAFDKIEDLENK 1589
Query: 181 R-TRRKLLEDLCD----------EFARGINEYEQEVHTLKQKSEK--DWVQRADHDRLVL 227
R T + L+DL + E + E ++ LK ++E+ D +Q + +L L
Sbjct: 1590 RKTLQNELDDLANTQGTADKNVHELEKAKRALESQLAELKAQNEELEDDLQLTEDAKLRL 1649
Query: 228 HISESWLDERMQMQLEAAQNGFMDKNSIVDKLSLEIETFIKAKQNSRSA----------- 276
++ L + + L A + G +K + K ++ET + ++ R+A
Sbjct: 1650 EVNMQALRSQFERDLLAKEEGAEEKRRGLVKQLRDLETELDEERKQRTAAVASKKKLEGD 1709
Query: 277 --ENQVIRDRRNSLESVPLNDAVSAPQAMGDD--DDDDSVGSDSHCFELNKPSHMGAKVH 332
E + + N ++ L A + D D +++ + L+K + K
Sbjct: 1710 LKEIETTMEMHNKVKEDALKHAKKLQAQVKDALRDAEEAKAAKEELQALSKEADGKVKAL 1769
Query: 333 KEEILDKNLDETSKSNVKKKKSVPGEGFKNHIPSNSNKKSQSVDAEEGLTTNIRLVEGTR 392
+ E+L D S ++ + I +N+NK S +D + L I +E
Sbjct: 1770 EAEVLQLTEDLASSERARRAAETERDELAEEIANNANKGSLMIDEKRRLEARIATLE-EE 1828
Query: 393 ISEEPEHFEI 402
+ EE + E+
Sbjct: 1829 LEEEQSNSEV 1838
Score = 45.8 bits (107), Expect = 4e-04
Identities = 37/167 (22%), Positives = 79/167 (47%), Gaps = 14/167 (8%)
Query: 71 EEQHSSNISL---------IKALKTELDRTRIKVKELLRDRQADRHEVDDLMKQIAEDKL 121
EEQ +S + L I+ L TEL + ++ R + +L ++AE +
Sbjct: 1831 EEQSNSEVLLDRSRKAQLQIEQLTTELANEKSNSQKNENGRALLERQNKELKAKLAEIET 1890
Query: 122 VRKSKEQDR---LHAAVQSVRDELEDERKLRKRSESIHRKLARELSEMKSSFTSALKDLE 178
+++K + L A + ++ ++LE+E K R + +RK+ +++ E+ + + ++
Sbjct: 1891 AQRTKVKATIATLEAKIANLEEQLENEGKERLLQQKANRKMDKKIKELTMNIEDERRHVD 1950
Query: 179 QERTRRKLLEDLCDEFARGINEYEQEVHTLKQKSEKDWVQRADHDRL 225
Q + + L R ++E E+E+ K+K++K QR D +
Sbjct: 1951 QHKEQMDKLNSRIKLLKRNLDETEEELQ--KEKTQKRKYQRECEDMI 1995
Score = 45.4 bits (106), Expect = 5e-04
Identities = 52/227 (22%), Positives = 102/227 (44%), Gaps = 30/227 (13%)
Query: 81 IKALKTELDRTRIKVKELLRDRQADRHEVDDLMKQIAEDKLVRK--SKEQDRLHAAVQSV 138
IK + +L T + ++LL++++ +DL + +AE++ K +K + + A + +
Sbjct: 1064 IKKYEEDLALTDDQNQKLLKEKKLLEERANDLSQTLAEEEEKAKHLAKLKAKHEATITEL 1123
Query: 139 RDELEDERKLRKRSESIHRKLARELSEMKSSFTSALKDLEQERTRRKLLEDLCDEFARGI 198
+ L +++ R+ S+ RK+ E++++K EQ RR ++++ + A+
Sbjct: 1124 EERLHKDQQQRQESDRSKRKIETEVADLK----------EQLNERRVQVDEMQAQLAKRE 1173
Query: 199 NEYEQEVHTLKQKS-EKDWVQRADHDRLVLHISESWLDERMQMQLEAAQNGFMDKNSIVD 257
E Q + + ++S K Q+A + ES L E +Q LEA + +
Sbjct: 1174 EELTQTLLRIDEESATKATAQKAQRE------LESQLAE-IQEDLEAEKAARAKAEKVRR 1226
Query: 258 KLSLEIETF----------IKAKQNSRSAENQVIRDRRNSLESVPLN 294
LS E+E A+Q RS Q + + SLE +N
Sbjct: 1227 DLSEELEALKNELLDSLDTTAAQQELRSKREQELATLKKSLEEETVN 1273
Score = 41.6 bits (96), Expect = 0.007
Identities = 25/132 (18%), Positives = 68/132 (50%), Gaps = 2/132 (1%)
Query: 81 IKALKTELDRT-RIKVKELLRDRQADRHEVDDLMKQIAEDKLVRKSKEQDRLHAAVQSVR 139
+KA E++ R KVK + +A +++ ++ +++L+++ K ++ ++ +
Sbjct: 1881 LKAKLAEIETAQRTKVKATIATLEAKIANLEEQLENEGKERLLQQ-KANRKMDKKIKELT 1939
Query: 140 DELEDERKLRKRSESIHRKLARELSEMKSSFTSALKDLEQERTRRKLLEDLCDEFARGIN 199
+EDER+ + + KL + +K + ++L++E+T+++ + C++
Sbjct: 1940 MNIEDERRHVDQHKEQMDKLNSRIKLLKRNLDETEEELQKEKTQKRKYQRECEDMIESQE 1999
Query: 200 EYEQEVHTLKQK 211
+E+++LK K
Sbjct: 2000 AMNREINSLKTK 2011
Score = 40.8 bits (94), Expect = 0.012
Identities = 43/186 (23%), Positives = 82/186 (43%), Gaps = 10/186 (5%)
Query: 81 IKALKTELDRTRIKVKELLRDRQADRHEVDDLMKQIAED--KLVRKSKEQDRLHAAVQSV 138
+KAL+ E+ + + R R+A E D+L ++IA + K E+ RL A + ++
Sbjct: 1766 VKALEAEVLQLTEDLASSERARRAAETERDELAEEIANNANKGSLMIDEKRRLEARIATL 1825
Query: 139 RDELEDERKLRKRSESIHRKLARELSEMKSSFTSALKDLEQERTRRKLLEDLCDEFARGI 198
+ELE+E+ + RK ++ ++ + + + ++ R LLE E +
Sbjct: 1826 EEELEEEQSNSEVLLDRSRKAQLQIEQLTTELANEKSNSQKNENGRALLERQNKELKAKL 1885
Query: 199 NEYEQEVHTLKQKSEKDWVQRADHDRLVLHISESWLDERMQMQLEAAQNGFMDKNSIVDK 258
E E T K A + + ++ E +E + L+ N MDK + +
Sbjct: 1886 AEIETAQRT------KVKATIATLEAKIANLEEQLENEGKERLLQQKANRKMDKK--IKE 1937
Query: 259 LSLEIE 264
L++ IE
Sbjct: 1938 LTMNIE 1943
Score = 40.4 bits (93), Expect = 0.015
Identities = 73/385 (18%), Positives = 160/385 (40%), Gaps = 51/385 (13%)
Query: 8 DRNNHALQPLSPASYGSSMEMTPYNPAATPNSSL--DFKGRIGEPHYSLKTSTELLKVLN 65
D+N H L+ A E+ N + L D K R+ +L++ E +L
Sbjct: 1608 DKNVHELEKAKRALESQLAELKAQNEELEDDLQLTEDAKLRLEVNMQALRSQFER-DLLA 1666
Query: 66 RIWSLEEQHSSNISLIKALKTELDRTRIKVKELLRDR---QADRHEVDDLMK---QIAED 119
+ EE+ + ++ L+TELD R + + + + D E++ M+ ++ ED
Sbjct: 1667 KEEGAEEKRRGLVKQLRDLETELDEERKQRTAAVASKKKLEGDLKEIETTMEMHNKVKED 1726
Query: 120 KLVRKSKEQDRLHAAVQSVRDELEDERKLRKRSESIHRKLARELSEMKSSFTSALKDLEQ 179
L K +L A V+ + E+ + ++ +++ ++ ++ +++ +DL
Sbjct: 1727 AL----KHAKKLQAQVKDALRDAEEAKAAKEELQALSKEADGKVKALEAEVLQLTEDLAS 1782
Query: 180 ERTRRKLLE----DLCDEFARGINE----------YEQEVHTLKQKSEKDW------VQR 219
R+ E +L +E A N+ E + TL+++ E++ + R
Sbjct: 1783 SERARRAAETERDELAEEIANNANKGSLMIDEKRRLEARIATLEEELEEEQSNSEVLLDR 1842
Query: 220 ADHDRLVLH-ISESWLDERMQMQLEAAQNGFMDKNSIVDKLSL-EIETFIKAKQNSRSA- 276
+ +L + ++ +E+ Q +++ + K L EIET + K + A
Sbjct: 1843 SRKAQLQIEQLTTELANEKSNSQKNENGRALLERQNKELKAKLAEIETAQRTKVKATIAT 1902
Query: 277 --------ENQVIRDRRNSLESVPLNDAVSAP-QAMGDDDDDDSVGSDSHCFELNKPSHM 327
E Q+ + + L N + + + + +D+ D H +++K +
Sbjct: 1903 LEAKIANLEEQLENEGKERLLQQKANRKMDKKIKELTMNIEDERRHVDQHKEQMDK---L 1959
Query: 328 GAKVHKEEILDKNLDETSKSNVKKK 352
+++ ++L +NLDET + K+K
Sbjct: 1960 NSRI---KLLKRNLDETEEELQKEK 1981
>MYHB_CHICK (P10587) Myosin heavy chain, gizzard smooth muscle
Length = 1978
Score = 57.8 bits (138), Expect = 9e-08
Identities = 83/392 (21%), Positives = 164/392 (41%), Gaps = 45/392 (11%)
Query: 42 DFKGRIGEPHYSLKTSTELLKVLNR-IWSLEEQHSSNISLIKALKTELDRTRIKVKELLR 100
D K ++ E +++T E K L R I SL +Q + L+ +R + ++ +L+
Sbjct: 1380 DSKKKLQEFTATVETMEEGKKKLQREIESLTQQFEEKAASYDKLEKTKNRLQQELDDLVV 1439
Query: 101 DRQADRHEVDDLMKQIAEDKLVRKSKEQDRLHAAVQSVRDELEDERKLRKRSESIHRKLA 160
D R V +L K K K+ D++ A +++ + DER R+E+ R+
Sbjct: 1440 DLDNQRQLVSNLEK---------KQKKFDQMLAEEKNISSKYADERD---RAEAEAREKE 1487
Query: 161 RELSEMKSSFTSALKDLEQ-ERTRRKL---LEDLC---DEFARGINEYEQEVHTLKQKSE 213
+ + + AL+ E+ ERT + L +EDL D+ + ++E E+ TL+Q+ E
Sbjct: 1488 TKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRTLEQQVE 1547
Query: 214 K---------DWVQRADHDRLVLHISESWLDERMQMQLEAAQNGFMDKNSIVDKLSLEIE 264
+ D +Q A+ +L L ++ + + + L+A +K + K E E
Sbjct: 1548 EMKTQLEELEDELQAAEDAKLRLEVNMQAMKSQFERDLQARDEQNEEKRRQLLKQLHEHE 1607
Query: 265 TFIKAKQNSRS---------------AENQVIRDRRNSLESVPLNDAVSAPQAMGDDDDD 309
T ++ ++ R+ E+QV + E++ + A D D
Sbjct: 1608 TELEDERKQRALAAAAKKKLEVDVKDLESQVDSANKAREEAIKQLRKLQAQMKDYQRDLD 1667
Query: 310 DSVGSDSHCFELNKPSHMGAKVHKEEILDKNLDETSKSNVKKKKSVPGEGFKNHIPSNSN 369
D+ + F + + AK + E++ D + +K+ + E + S ++
Sbjct: 1668 DARAAREEIFATARENEKKAKNLEAELIQLQEDLAAAERARKQADLEKEEMAEELASANS 1727
Query: 370 KKSQSVDAEEGLTTNIRLVEGTRISEEPEHFE 401
++ D + L I +E + EE + E
Sbjct: 1728 GRTSLQDEKRRLEARIAQLE-EELDEEHSNIE 1758
Score = 51.6 bits (122), Expect = 7e-06
Identities = 63/277 (22%), Positives = 122/277 (43%), Gaps = 43/277 (15%)
Query: 61 LKVLNRIWSLEEQHSSNISLIKALKTELDRTRIKVKELLRDRQADRHEVDDLMKQIAEDK 120
++V N L E S NI L K + T L +ELL++ + V ++Q+ +DK
Sbjct: 1292 IEVENVTSLLNEAESKNIKLTKDVAT-LGSQLQDTQELLQEETRQKLNVTTKLRQLEDDK 1350
Query: 121 ------LVRKSKEQDRLHAAVQSVRDELED-ERKLRKRSESIH------RKLARELSEMK 167
L + + + L + ++ +L D ++KL++ + ++ +KL RE+ +
Sbjct: 1351 NSLQEQLDEEVEAKQNLERHISTLTIQLSDSKKKLQEFTATVETMEEGKKKLQREIESLT 1410
Query: 168 SSFTSALKDLEQ-ERTRRKLLEDLCDEFARGINEYEQEVHTLKQKSEKDWVQRADHDRLV 226
F ++ E+T+ +L ++L D+ ++ Q V L++K +K A+
Sbjct: 1411 QQFEEKAASYDKLEKTKNRLQQEL-DDLVVDLDNQRQLVSNLEKKQKKFDQMLAEEK--- 1466
Query: 227 LHISESWLDERMQMQLEAAQNGFMDKNSIVDKLSLEIETFIKAKQNSRSAENQVIRDRRN 286
+IS + DER + + EA +K + L+ +E ++AK+ +R N
Sbjct: 1467 -NISSKYADERDRAEAEA-----REKETKALSLARALEEALEAKEE---------LERTN 1511
Query: 287 SLESVPLNDAVSAPQAMGDDDDDDSVGSDSHCFELNK 323
+ + D VS+ D VG + H E +K
Sbjct: 1512 KMLKAEMEDLVSS---------KDDVGKNVHELEKSK 1539
Score = 41.6 bits (96), Expect = 0.007
Identities = 46/250 (18%), Positives = 105/250 (41%), Gaps = 37/250 (14%)
Query: 59 ELLKVLNRIWSLEEQHSSNISLIKALKTELDRTRIKVKELLRDRQADRHEV-------DD 111
EL ++L+ + + E+ ++A K ++ + + ++E L + +A R ++ D
Sbjct: 924 ELEEILHEMEARIEEEEERSQQLQAEKKKMQQQMLDLEEQLEEEEAARQKLQLEKVTADG 983
Query: 112 LMKQIAEDKLV------RKSKEQDRLHAAVQSVRDELEDERKLRKRSESIHRKLARELSE 165
+K++ +D L+ + +KE+ L V + L +E + K + K +SE
Sbjct: 984 KIKKMEDDILIMEDQNNKLTKERKLLEERVSDLTTNLAEEEEKAKNLTKLKNKHESMISE 1043
Query: 166 MKSSFTSALKDLEQERTRRKLLEDLCDEFARGINEYEQEVHTLKQKSEKDWVQRADHDRL 225
++ K ++ ++ LE + I E + ++ LK + K
Sbjct: 1044 LEVRLKKEEKSRQELEKIKRKLEGESSDLHEQIAELQAQIAELKAQLAKK---------- 1093
Query: 226 VLHISESWLDERMQMQLEAAQNGFMDKNSIVDKLSLEIETFIKAKQ----NSRSAENQVI 281
+E +Q L ++ KN+ + K+ E+E+ I Q + ++A N+
Sbjct: 1094 ---------EEELQAALARLEDETSQKNNALKKIR-ELESHISDLQEDLESEKAARNKAE 1143
Query: 282 RDRRNSLESV 291
+ +R+ E +
Sbjct: 1144 KQKRDLSEEL 1153
Score = 40.8 bits (94), Expect = 0.012
Identities = 53/292 (18%), Positives = 121/292 (41%), Gaps = 19/292 (6%)
Query: 70 LEEQ-HSSNISLIKALKTELDRTRIKVKELLRDRQADRHEVDDLMKQIAEDKLVRKSKEQ 128
LE Q S+N + +A+K +L + + ++K+ RD R +++ E++ K+
Sbjct: 1634 LESQVDSANKAREEAIK-QLRKLQAQMKDYQRDLDDARAAREEIFATARENE-----KKA 1687
Query: 129 DRLHAAVQSVRDELEDERKLRKRSESIHRKLARELSEMKSSFTSALKDLEQERTRRKLLE 188
L A + ++++L + RK+++ ++A EL+ S TS + + R LE
Sbjct: 1688 KNLEAELIQLQEDLAAAERARKQADLEKEEMAEELASANSGRTSLQDEKRRLEARIAQLE 1747
Query: 189 DLCDEFARGINEYEQEVHTLKQK---------SEKDWVQRADHDRLVLHISESWLDERMQ 239
+ DE I + Q+ +E+ Q+ ++ R L L ++Q
Sbjct: 1748 EELDEEHSNIETMSDRMRKAVQQAEQLNNELATERATAQKNENARQQLERQNKELRSKLQ 1807
Query: 240 MQLEAAQNGFMDKNSIVDKLSLEIETFIKAKQNSRSAENQVIRDRRNSLES--VPLNDAV 297
A ++ F + ++ +E ++ + + A + +R + L+ + + D
Sbjct: 1808 EMEGAVKSKFKSTIAALEAKIASLEEQLEQEAREKQAAAKTLRQKDKKLKDALLQVEDER 1867
Query: 298 SAPQAMGDDDDDDSVGSDSHCFELNKPSHMGAKVH-KEEILDKNLDETSKSN 348
+ D + ++ +L + +++ L + LDE ++SN
Sbjct: 1868 KQAEQYKDQAEKGNLRLKQLKRQLEEAEEESQRINANRRKLQRELDEATESN 1919
Score = 35.4 bits (80), Expect = 0.49
Identities = 49/252 (19%), Positives = 113/252 (44%), Gaps = 26/252 (10%)
Query: 61 LKVLNRIWSLEEQHSSNISLIKALKTELDRTRIKVKELLRDRQADRHEVDDLMKQI---- 116
+K L ++ EE+ + ++ K + ++KEL + E + L +++
Sbjct: 846 VKPLLQVTRQEEEMQAKDEELQRTKERQQKAEAELKELEQKHTQLCEEKNLLQEKLQAET 905
Query: 117 -----AEDKLVRKSKEQDRLHAAVQSVRDELEDERKLRKRSESIHRKLARELSEMKSSFT 171
AE+ VR + ++ L + + +E+E + ++ ++ +K+ +++ +++
Sbjct: 906 ELYAEAEEMRVRLAAKKQELEEILHEMEARIEEEEERSQQLQAEKKKMQQQMLDLEEQLE 965
Query: 172 SALKDLEQERTRRKL-LEDLCDEFARGINEYEQEVHTLKQKSEKDWVQRADHDRLVLHIS 230
E+E R+KL LE + + I + E ++ ++ ++ K +R +L
Sbjct: 966 ------EEEAARQKLQLEKVTAD--GKIKKMEDDILIMEDQNNK-----LTKERKLLEER 1012
Query: 231 ESWLDERMQMQLEAAQNGFMDKNSIVDKLSLEIETFIKAKQNSRSAENQVIRDRRNSLES 290
S L + + E A+N KN +S E+E +K ++ SR ++ R+ ES
Sbjct: 1013 VSDLTTNLAEEEEKAKNLTKLKNKHESMIS-ELEVRLKKEEKSRQELEKI--KRKLEGES 1069
Query: 291 VPLNDAVSAPQA 302
L++ ++ QA
Sbjct: 1070 SDLHEQIAELQA 1081
Score = 31.6 bits (70), Expect = 7.1
Identities = 30/105 (28%), Positives = 50/105 (47%), Gaps = 14/105 (13%)
Query: 66 RIWSLEEQHSSNISLIKALKTELDRTRIKVKELLRDRQADRHEVDDLMKQIAEDKLVRKS 125
+I SLEEQ L+ E + K L RQ D+ D L++ E K +
Sbjct: 1827 KIASLEEQ----------LEQEAREKQAAAKTL---RQKDKKLKDALLQVEDERKQAEQY 1873
Query: 126 KEQ-DRLHAAVQSVRDELEDERKLRKRSESIHRKLARELSEMKSS 169
K+Q ++ + ++ ++ +LE+ + +R + RKL REL E S
Sbjct: 1874 KDQAEKGNLRLKQLKRQLEEAEEESQRINANRRKLQRELDEATES 1918
>MYHA_HUMAN (P35580) Myosin heavy chain, nonmuscle type B (Cellular
myosin heavy chain, type B) (Nonmuscle myosin heavy
chain-B) (NMMHC-B)
Length = 1976
Score = 57.4 bits (137), Expect = 1e-07
Identities = 76/378 (20%), Positives = 158/378 (41%), Gaps = 46/378 (12%)
Query: 64 LNRIWSLEEQHSSNISLIKALKTELDRTRIKVKELLRDRQADRHEVDDL------MKQIA 117
L I SLEE + +AL L+ + +L + + + E+DDL +Q+A
Sbjct: 1384 LGTIESLEEAKKKLLKDAEALSQRLEEKALAYDKLEKTKNRLQQELDDLTVDLDHQRQVA 1443
Query: 118 EDKLVRKSKEQDRLHAAVQSVRDELEDERKLRKRSESIHRKLARELSEMKSSFTSALKDL 177
+ L +K K+ D+L A +S+ +E R R+E+ R+ + + + AL+
Sbjct: 1444 SN-LEKKQKKFDQLLAEEKSISARYAEE---RDRAEAEAREKETKALSLARALEEALEAK 1499
Query: 178 EQ-ERTRRKL---LEDLC---DEFARGINEYEQEVHTLKQKSE---------KDWVQRAD 221
E+ ER ++L +EDL D+ + ++E E+ L+Q+ E +D +Q +
Sbjct: 1500 EEFERQNKQLRADMEDLMSSKDDVGKNVHELEKSKRALEQQVEEMRTQLEELEDELQATE 1559
Query: 222 HDRLVLHISESWLDERMQMQLEAAQNGFMDKNSIVDKLSLEIETFIKAKQNSRSAENQVI 281
+L L ++ + + + L+ +K ++ K E+E ++ ++ R+ V
Sbjct: 1560 DAKLRLEVNMQAMKAQFERDLQTRDEQNEEKKRLLIKQVRELEAELEDERKQRAL--AVA 1617
Query: 282 RDRRNSLESVPLNDAVSAPQAMGDD-----------------DDDDSVGSDSHCFELNKP 324
++ ++ L + A D+ + +++ S F +K
Sbjct: 1618 SKKKMEIDLKDLEAQIEAANKARDEVIKQLRKLQAQMKDYQRELEEARASRDEIFAQSKE 1677
Query: 325 SHMGAKVHKEEILDKNLDETSKSNVKKKKSVPGEGFKNHIPSNSNKKSQSVDAEEGLTTN 384
S K + EIL + S ++ + + I ++++ KS +D + L
Sbjct: 1678 SEKKLKSLEAEILQLQEELASSERARRHAEQERDELADEITNSASGKSALLDEKRRLEAR 1737
Query: 385 IRLVEGTRISEEPEHFEI 402
I +E + EE + E+
Sbjct: 1738 IAQLE-EELEEEQSNMEL 1754
Score = 44.7 bits (104), Expect = 8e-04
Identities = 74/372 (19%), Positives = 156/372 (41%), Gaps = 41/372 (11%)
Query: 43 FKGRIGEPHYSLKTSTELL----KVLNRIWSLEEQHS-----SNISLIKALKTELDRTRI 93
FK + + L+T + L KVL ++ E +H + + + A +E DR R+
Sbjct: 1218 FKANLEKNKQGLETDNKELACEVKVLQQV-KAESEHKRKKLDAQVQELHAKVSEGDRLRV 1276
Query: 94 KVKELLRDRQADRHEVDDLMKQIAEDKLVRKSKEQDRLHAAVQSVRDELEDERKLRKRSE 153
++ E Q + V L+++ AE K ++ +K+ L + +Q ++ L++E + +
Sbjct: 1277 ELAEKASKLQNELDNVSTLLEE-AEKKGIKFAKDAASLESQLQDTQELLQEETRQKLNLS 1335
Query: 154 SIHRKLARELSEMKSSFTSALKDLEQERTRRKLLED----LCDEFARGINEYEQEVHTLK 209
S R+L E + ++ + E+E RK LE L + A + + ++ T++
Sbjct: 1336 SRIRQLEEEKNSLQ-------EQQEEEEEARKNLEKQVLALQSQLADTKKKVDDDLGTIE 1388
Query: 210 QKSEKDWVQRADHDRLVLHISESWL--------DERMQMQLEAAQNGFMDKNSIVDKLSL 261
E D + L + E L R+Q +L+ + + L
Sbjct: 1389 SLEEAKKKLLKDAEALSQRLEEKALAYDKLEKTKNRLQQELDDLTVDLDHQRQVASNLEK 1448
Query: 262 EIETF--IKAKQNSRSAENQVIRDRRNSLESVPLNDAVSAPQAMGDDDDDDSVGSDSHCF 319
+ + F + A++ S SA RDR + A+S +A+ ++++ +
Sbjct: 1449 KQKKFDQLLAEEKSISARYAEERDRAEAEAREKETKALSLARAL-----EEALEAKEEFE 1503
Query: 320 ELNKP--SHMGAKVHKEEILDKNLDETSKSNVKKKKSVPGEGFKNHIPSNSNKKSQSVDA 377
NK + M + ++ + KN+ E KS ++ V E + + ++ + DA
Sbjct: 1504 RQNKQLRADMEDLMSSKDDVGKNVHELEKSKRALEQQV--EEMRTQLEELEDELQATEDA 1561
Query: 378 EEGLTTNIRLVE 389
+ L N++ ++
Sbjct: 1562 KLRLEVNMQAMK 1573
Score = 43.5 bits (101), Expect = 0.002
Identities = 51/253 (20%), Positives = 115/253 (45%), Gaps = 27/253 (10%)
Query: 82 KALKTELDRTRIKVKELLRDRQAD-----RHEVD--DLMKQIAEDKLVRKSKEQDRLHAA 134
+AL+ +++ R +++EL + QA R EV+ + Q D R + +++
Sbjct: 1535 RALEQQVEEMRTQLEELEDELQATEDAKLRLEVNMQAMKAQFERDLQTRDEQNEEKKRLL 1594
Query: 135 VQSVRD---ELEDERKLRKRSESIHRKLARELSEMKSSFTSALKDLEQERTRRKLLEDLC 191
++ VR+ ELEDERK R + + +K+ +L ++++ +A K ++ + + L+
Sbjct: 1595 IKQVRELEAELEDERKQRALAVASKKKMEIDLKDLEAQIEAANKARDEVIKQLRKLQAQM 1654
Query: 192 DEFARGINEYEQEVHTLKQKSEKDWVQRADHDRLVLHISESWL-DERMQMQLEAAQNGFM 250
++ R + E + +S++ + + +L + E ER + E ++
Sbjct: 1655 KDYQRELEEARASRDEIFAQSKESEKKLKSLEAEILQLQEELASSERARRHAEQERDELA 1714
Query: 251 DK--NSIVDKLSL------------EIETFIKAKQNSRSAENQVIRDRRNSLESVPLNDA 296
D+ NS K +L ++E ++ +Q++ N R R+ +L+ LN
Sbjct: 1715 DEITNSASGKSALLDEKRRLEARIAQLEEELEEEQSNMELLND--RFRKTTLQVDTLNAE 1772
Query: 297 VSAPQAMGDDDDD 309
++A ++ D+
Sbjct: 1773 LAAERSAAQKSDN 1785
Score = 40.8 bits (94), Expect = 0.012
Identities = 50/245 (20%), Positives = 108/245 (43%), Gaps = 35/245 (14%)
Query: 34 AATPNSSLDFKGRIGEPHYSLKTSTELLKVLNRIWS--------LEEQHSSNISL----- 80
A+ +D K + + K E++K L ++ + LEE +S +
Sbjct: 1617 ASKKKMEIDLKDLEAQIEAANKARDEVIKQLRKLQAQMKDYQRELEEARASRDEIFAQSK 1676
Query: 81 -----IKALKTELDRTRIKVKELLRDRQADRHEVDDLMKQIAEDKLVRKS--KEQDRLHA 133
+K+L+ E+ + + ++ R R+ E D+L +I + + E+ RL A
Sbjct: 1677 ESEKKLKSLEAEILQLQEELASSERARRHAEQERDELADEITNSASGKSALLDEKRRLEA 1736
Query: 134 AVQSVRDELEDE-----------RKLRKRSESIHRKLARELSEMKSSFTSALKDLEQERT 182
+ + +ELE+E RK + ++++ +LA E S + S + + Q +
Sbjct: 1737 RIAQLEEELEEEQSNMELLNDRFRKTTLQVDTLNAELAAERSAAQKSDNARQQLERQNKE 1796
Query: 183 RRKLLEDL----CDEFARGINEYEQEVHTLKQKSEKDWVQRADHDRLVLHISESWLDERM 238
+ L++L +F I+ E ++ L+++ E++ +RA ++LV + + M
Sbjct: 1797 LKAKLQELEGAVKSKFKATISALEAKIGQLEEQLEQEAKERAAANKLVRRTEKKLKEIFM 1856
Query: 239 QMQLE 243
Q++ E
Sbjct: 1857 QVEDE 1861
Score = 40.4 bits (93), Expect = 0.015
Identities = 43/209 (20%), Positives = 87/209 (41%), Gaps = 24/209 (11%)
Query: 93 IKVKELLRDRQADRHEVDDLMKQIAEDKLVRKS--KEQDRLHAAVQSVRDELEDERKLRK 150
IK K+L+ DR A+ Q+AE++ K+ K +++ + + + L+ E K R+
Sbjct: 998 IKEKKLMEDRIAE------CSSQLAEEEEKAKNLAKIRNKQEVMISDLEERLKKEEKTRQ 1051
Query: 151 RSESIHRKLARELSEMKSSFTSALKDLEQERTR-RKLLEDLCDEFARG------------ 197
E RKL E ++++ +++ + + K E+L ARG
Sbjct: 1052 ELEKAKRKLDGETTDLQDQIAELQAQIDELKLQLAKKEEELQGALARGDDETLHKNNALK 1111
Query: 198 -INEYEQEVHTLKQKSEKDWVQRADHDRLVLHISESWLDERMQMQLEAAQNGFMDKNSIV 256
+ E + ++ L++ E + R ++ +SE E ++ +LE + + +
Sbjct: 1112 VVRELQAQIAELQEDFESEKASRNKAEKQKRDLSEEL--EALKTELEDTLDTTAAQQELR 1169
Query: 257 DKLSLEIETFIKAKQNSRSAENQVIRDRR 285
K E+ KA + I+D R
Sbjct: 1170 TKREQEVAELKKALEEETKNHEAQIQDMR 1198
Score = 36.6 bits (83), Expect = 0.22
Identities = 75/374 (20%), Positives = 151/374 (40%), Gaps = 56/374 (14%)
Query: 44 KGRIGEPHYSLKTSTELLKVLNRIWSLEEQHSSNISLIKALKTELD-----RTRIKVKEL 98
K + E + L++ E + N+I L+ + + I+ L+ +LD R +++++++
Sbjct: 917 KQELEEILHDLESRVEEEEERNQI--LQNEKKKMQAHIQDLEEQLDEEEGARQKLQLEKV 974
Query: 99 LRDRQADRHEVDDLMKQIAEDKLVRKSKEQDRLHAAVQSVRDELEDERKLRKRSESIHRK 158
+ + + E + L+ ED+ + KE+ + + +L +E + K I K
Sbjct: 975 TAEAKIKKMEEEILL---LEDQNSKFIKEKKLMEDRIAECSSQLAEEEEKAKNLAKIRNK 1031
Query: 159 LARELSEMKSSFTSALKDLEQ-ERTRRKL---LEDLCDEFARGINEYEQEVHTLKQKSEK 214
+S+++ K ++ E+ +RKL DL D+ A E + ++ LK + K
Sbjct: 1032 QEVMISDLEERLKKEEKTRQELEKAKRKLDGETTDLQDQIA----ELQAQIDELKLQLAK 1087
Query: 215 DWVQRADHDRLVLHISESWLDERMQMQLEAAQNGFMDKNS---IVDKLSLEI----ETFI 267
+E +Q L + + KN+ +V +L +I E F
Sbjct: 1088 K-------------------EEELQGALARGDDETLHKNNALKVVRELQAQIAELQEDFE 1128
Query: 268 KAKQNSRSAENQVIRDRRNSLESV--PLNDAVSAPQAMGDDDDDDSVGSDSHCFELNKPS 325
K + AE Q RD LE++ L D + A + + EL K
Sbjct: 1129 SEKASRNKAEKQK-RDLSEELEALKTELEDTLDTTAA----QQELRTKREQEVAELKKAL 1183
Query: 326 HMGAKVHKEEILDKNLDETSKSNVKKKKSVPGEGFKNHIPSNSNKKSQSVDAEEGLTTNI 385
K H+ +I D + ++ + FK ++ NK+ D +E L +
Sbjct: 1184 EEETKNHEAQIQDMRQRHATALEELSEQLEQAKRFKANL--EKNKQGLETDNKE-LACEV 1240
Query: 386 RLVEGTRISEEPEH 399
++++ ++ E EH
Sbjct: 1241 KVLQ--QVKAESEH 1252
Score = 34.7 bits (78), Expect = 0.84
Identities = 24/100 (24%), Positives = 45/100 (45%), Gaps = 12/100 (12%)
Query: 66 RIWSLEEQHSSNISLIKALKTELDRTRIKVKELLRDRQADRHEVDDLMKQIAEDKLVRKS 125
+I LEEQ A + RT K+KE+ + +R D +Q+
Sbjct: 1822 KIGQLEEQLEQEAKERAAANKLVRRTEKKLKEIFMQVEDERRHADQYKEQM--------- 1872
Query: 126 KEQDRLHAAVQSVRDELEDERKLRKRSESIHRKLARELSE 165
++ +A ++ ++ +LE+ + R+ + RKL REL +
Sbjct: 1873 ---EKANARMKQLKRQLEEAEEEATRANASRRKLQRELDD 1909
Score = 32.7 bits (73), Expect = 3.2
Identities = 36/139 (25%), Positives = 69/139 (48%), Gaps = 16/139 (11%)
Query: 81 IKALKTELD-RTRIKVKELLRDRQADRHEVDDLMKQIAED-----KLVRKS-KEQDRLHA 133
+KA EL+ + K K + +A ++++ ++Q A++ KLVR++ K+ +
Sbjct: 1797 LKAKLQELEGAVKSKFKATISALEAKIGQLEEQLEQEAKERAAANKLVRRTEKKLKEIFM 1856
Query: 134 AVQSVRDELEDERKLRKRSESIHRKLARELSEMKSSFTSALKDLEQERTRRKLLEDLCDE 193
V+ R + ++ +++ + ++L R+L E + T A +RRKL +L D
Sbjct: 1857 QVEDERRHADQYKEQMEKANARMKQLKRQLEEAEEEATRA------NASRRKLQRELDD- 1909
Query: 194 FARGINE-YEQEVHTLKQK 211
A NE +EV TLK +
Sbjct: 1910 -ATEANEGLSREVSTLKNR 1927
>MYH9_HUMAN (P35579) Myosin heavy chain, nonmuscle type A (Cellular
myosin heavy chain, type A) (Nonmuscle myosin heavy
chain-A) (NMMHC-A)
Length = 1960
Score = 56.2 bits (134), Expect = 3e-07
Identities = 95/463 (20%), Positives = 184/463 (39%), Gaps = 83/463 (17%)
Query: 58 TELLKVLNRIWSLEEQHSSNISLIKALKTELDRTRIKVKELLRDRQADRHEVDDLMKQIA 117
T+L L+ + L Q S S + + L+ +ELL++ + + +KQ+
Sbjct: 1276 TKLQVELDNVTGLLSQSDSKSSKLTKDFSALESQLQDTQELLQEENRQKLSLSTKLKQVE 1335
Query: 118 EDK-LVRKSKEQDR------------LHAAVQSVRDELEDERKLRKRSESIHRKLARE-- 162
++K R+ E++ LHA V ++ ++ED + +E + RKL ++
Sbjct: 1336 DEKNSFREQLEEEEEAKHNLEKQIATLHAQVADMKKKMEDSVGCLETAEEVKRKLQKDLE 1395
Query: 163 -LSEMKSSFTSALKDLEQERTRRKLLEDLCDEFARGINEYEQEVHTLKQKSEKDWVQRAD 221
LS+ +A LE+ +TR L+ D+ ++ Q L++K +K
Sbjct: 1396 GLSQRHEEKVAAYDKLEKTKTR---LQQELDDLLVDLDHQRQSACNLEKKQKK------- 1445
Query: 222 HDRLVLH---ISESWLDERMQMQLEA------------AQNGFMDKNSIVDKLS----LE 262
D+L+ IS + +ER + + EA A M++ + +++L+ E
Sbjct: 1446 FDQLLAEEKTISAKYAEERDRAEAEAREKETKALSLARALEEAMEQKAELERLNKQFRTE 1505
Query: 263 IETFIKAK----------QNSRSAENQVIRDRRNSLESVPLNDAVSAP-----------Q 301
+E + +K + S+ A Q + + + LE L D + A Q
Sbjct: 1506 MEDLMSSKDDVGKSVHELEKSKRALEQQVEEMKTQLEE--LEDELQATEDAKLRLEVNLQ 1563
Query: 302 AMGDDDDDDSVGSDSHCFELNKPSHMGAKVHKEEILDKNLDETSKSNVKKKKSVPGEGFK 361
AM + D G D E K + + E+ D+ + +KK + + +
Sbjct: 1564 AMKAQFERDLQGRDEQSEEKKKQLVRQVREMEAELEDERKQRSMAVAARKKLEMDLKDLE 1623
Query: 362 NHIPSNSNKKSQSVDAEEGLTTN----IRLVEGTRISEEPEHFEISESGGFERKNNLSEL 417
HI S + + +++ L +R ++ TR S E EI + K N +L
Sbjct: 1624 AHIDSANKNRDEAIKQLRKLQAQMKDCMRELDDTRASRE----EILA----QAKENEKKL 1675
Query: 418 HSTSKNHIIDNLIRGQLLASESGKNNKHAEHNNYGEASCSNAG 460
S I ++ +L A+E K E + + +++G
Sbjct: 1676 KSMEAEMI---QLQEELAAAERAKRQAQQERDELADEIANSSG 1715
Score = 42.7 bits (99), Expect = 0.003
Identities = 56/283 (19%), Positives = 124/283 (43%), Gaps = 13/283 (4%)
Query: 81 IKALKTELDRTRIKVKELLRDRQADRHEVDDLMKQIAEDKLVRKSKEQD---RLHAAVQS 137
++ALKTEL+ T R EV+ L K + E+ +++ Q+ + AV+
Sbjct: 1141 LEALKTELEDTLDSTAAQQELRSKREQEVNILKKTLEEEAKTHEAQIQEMRQKHSQAVEE 1200
Query: 138 VRDELEDERKLRKRSESIHRKLARELSEMKSSFTSALKDLEQERTRRKLLEDLCDEFARG 197
+ ++LE ++++ E + L E E+ + L+ +RK +E E
Sbjct: 1201 LAEQLEQTKRVKANLEKAKQTLENERGELANEVKVLLQGKGDSEHKRKKVEAQLQELQVK 1260
Query: 198 INEYEQEVHTLKQKSEKDWVQRADHDRLVLHISESWLDERMQMQLEAAQNGFMDKNSIV- 256
NE E+ L K K V+ D+ +L S+S ++ A ++ D ++
Sbjct: 1261 FNEGERVRTELADKVTKLQVE-LDNVTGLLSQSDS-KSSKLTKDFSALESQLQDTQELLQ 1318
Query: 257 --DKLSLEIETFIKAKQNSRSAENQVIRDRRNSLESVPLNDA-VSAPQAMGDDDDDDSVG 313
++ L + T +K ++ +++ + + + + ++ A + A A +DSVG
Sbjct: 1319 EENRQKLSLSTKLKQVEDEKNSFREQLEEEEEAKHNLEKQIATLHAQVADMKKKMEDSVG 1378
Query: 314 ----SDSHCFELNKPSHMGAKVHKEEILDKNLDETSKSNVKKK 352
++ +L K ++ H+E++ + E +K+ ++++
Sbjct: 1379 CLETAEEVKRKLQKDLEGLSQRHEEKVAAYDKLEKTKTRLQQE 1421
Score = 41.2 bits (95), Expect = 0.009
Identities = 77/359 (21%), Positives = 135/359 (37%), Gaps = 62/359 (17%)
Query: 42 DFKGRIGEPHYSLK-TSTELLKVLNRIWSLEEQHSSNISLIKALKTELDRTRIKVKELLR 100
D + R+ E + E K+ I LEEQ S + L+ E T K+K+L
Sbjct: 919 DLEARVEEEEERCQHLQAEKKKMQQNIQELEEQLEEEESARQKLQLEKVTTEAKLKKLEE 978
Query: 101 DRQADRHEVDDLMKQIAEDKLVRKSKEQDRLHAAVQSVRDELEDERKLRKRSESIHRKLA 160
++ I ED+ + +KE+ L + L +E + K + K
Sbjct: 979 EQI------------ILEDQNCKLAKEKKLLEDRIAEFTTNLTEEEEKSKSLAKLKNKHE 1026
Query: 161 RELSEMKSSFTSALKDLEQ-ERTRRKLLEDLCDEFARGINEYEQEVHTLKQKSEKDWVQR 219
+++++ K ++ E+TRRKL D D + I E + ++ LK + K
Sbjct: 1027 AMITDLEERLRREEKQRQELEKTRRKLEGDSTD-LSDQIAELQAQIAELKMQLAKK---- 1081
Query: 220 ADHDRLVLHISESWLDERMQMQLEAAQNGFMDKNSIVDKLSLEIETFIKAKQNSRSAENQ 279
+E +Q L + KN + K+ E+E+ I Q +E
Sbjct: 1082 ---------------EEELQAALARVEEEAAQKNMALKKIR-ELESQISELQEDLESE-- 1123
Query: 280 VIRDRRNSLESV--PLNDAVSAPQAMGDDDDDDSVGSDSHCFELNKPSHMGAKVHKEEIL 337
R RN E L + + A + +D D + EL + + IL
Sbjct: 1124 --RASRNKAEKQKRDLGEELEALKTELEDTLDSTAAQQ----ELR-----SKREQEVNIL 1172
Query: 338 DKNLDETSKSN------VKKKKSVPGEGF------KNHIPSNSNKKSQSVDAEEGLTTN 384
K L+E +K++ +++K S E + +N K Q+++ E G N
Sbjct: 1173 KKTLEEEAKTHEAQIQEMRQKHSQAVEELAEQLEQTKRVKANLEKAKQTLENERGELAN 1231
Score = 33.9 bits (76), Expect = 1.4
Identities = 51/249 (20%), Positives = 107/249 (42%), Gaps = 23/249 (9%)
Query: 73 QHSSNISLIKALKTELDRTRIKVKELLRDRQADRHEVDDLMKQIAED--KLVRKSKEQDR 130
Q N +K+++ E+ + + ++ R ++ + E D+L +IA K +E+ R
Sbjct: 1667 QAKENEKKLKSMEAEMIQLQEELAAAERAKRQAQQERDELADEIANSSGKGALALEEKRR 1726
Query: 131 LHAAVQSVRDELEDE-----------RKLRKRSESIHRKLARELSEMKSSFTSALKDLEQ 179
L A + + +ELE+E +K + + I+ L E S + + +A + LE+
Sbjct: 1727 LEARIAQLEEELEEEQGNTELINDRLKKANLQIDQINTDLNLERSHAQKN-ENARQQLER 1785
Query: 180 ERTRRKL-LEDL----CDEFARGINEYEQEVHTLKQKSEKDWVQRADHDRLVLHISESWL 234
+ K+ L+++ ++ I E ++ L+++ + + +R + V +
Sbjct: 1786 QNKELKVKLQEMEGTVKSKYKASITALEAKIAQLEEQLDNETKERQAACKQVRRTEKKLK 1845
Query: 235 DERMQMQLEAAQNGFMDKNSIVDKLSLEIETFIKAKQNSRSAENQVIRDRRNSLESVPLN 294
D +Q+ + +N K+ DK S ++ +K + E Q R L+ L
Sbjct: 1846 DVLLQVD-DERRNAEQYKDQ-ADKASTRLKQ-LKRQLEEAEEEAQRANASRRKLQR-ELE 1901
Query: 295 DAVSAPQAM 303
DA AM
Sbjct: 1902 DATETADAM 1910
Score = 33.1 bits (74), Expect = 2.5
Identities = 30/128 (23%), Positives = 57/128 (44%), Gaps = 12/128 (9%)
Query: 38 NSSLDFKGRIGEPHYSLKTSTELLKVLNRIWSLEEQHSSNISLIKALKTELDRTRIKVKE 97
N L K + E K + + +I LEEQ + +A ++ RT K+K+
Sbjct: 1787 NKELKVKLQEMEGTVKSKYKASITALEAKIAQLEEQLDNETKERQAACKQVRRTEKKLKD 1846
Query: 98 LLRDRQADRHEVDDLMKQIAEDKLVRKSKEQDRLHAAVQSVRDELEDERKLRKRSESIHR 157
+L +VDD + + K + D+ ++ ++ +LE+ + +R+ + R
Sbjct: 1847 VLL-------QVDDERRNAEQYK-----DQADKASTRLKQLKRQLEEAEEEAQRANASRR 1894
Query: 158 KLARELSE 165
KL REL +
Sbjct: 1895 KLQRELED 1902
>TAXB_CHICK (Q9I969) Beta-taxilin (Muscle derived protein 77)
Length = 676
Score = 55.8 bits (133), Expect = 4e-07
Identities = 72/324 (22%), Positives = 135/324 (41%), Gaps = 24/324 (7%)
Query: 57 STELLKVLNRI---WSLEEQHSSNISLIKALKTELDRTRIKVKELLRDRQADRH--EVDD 111
+TEL + L I + L E+H I + L+ +L +++ + + +RH E +
Sbjct: 273 NTELAEKLKSIIDQYELREEHLDKIFKHRELQQKLVDAKLEQSQEMMKEAEERHQKEKEY 332
Query: 112 LMKQIAEDKLVRKS-KEQDR-LHAAVQSVRDELEDERKLRKRSESIHRKLARELSEMKSS 169
L+ Q AE KL K KEQ+ L A + + E+ +K +S + +E+ +M
Sbjct: 333 LLNQAAEWKLQAKMLKEQETVLQAQITLYSERFEEFQKTLTKSNEVFATFKQEMEKMTKK 392
Query: 170 FTSALKDLEQERTR----RKLLEDLCDEFARGINEYEQEVHTLKQKSEKDWVQRADHDRL 225
KD ++R + L D+ +E A EYE V +++ + + + L
Sbjct: 393 MKKLEKDTATWKSRFENCNRALLDMIEEKAMRTKEYECFVLKIQRLENLCRALQEERNEL 452
Query: 226 VLHISESWLDERMQMQLEAAQNGFMDKN-SIVDKLSLE--------IETFIKAKQNSRSA 276
I ++ L E + ++ + N S ++ S+E ++ +A + S A
Sbjct: 453 YRKIKQAQLPEEVNGNDILEEDDDANTNPSSSEQASIELCAADKNMLQELAEAFRVSHKA 512
Query: 277 ENQVIRDRRN-SLESVPLNDAVSAPQAMGDDDDDDSVGSDSHCFELN---KPSHMGAKVH 332
E + D N +V + +A+S P+ G+ F ++ P HM A
Sbjct: 513 EETLPSDGSNPETCNVQMCEAISVPELPSHLTSQPEAGNHCEQFSMSTSAPPEHMPAATE 572
Query: 333 KEEILDKNLDETSKSNVKKKKSVP 356
L +N+ + +KS + VP
Sbjct: 573 NMTTLIENMPKPTKSMPMPPEMVP 596
>MYSB_CAEEL (P02566) Myosin heavy chain B (MHC B)
Length = 1966
Score = 55.8 bits (133), Expect = 4e-07
Identities = 73/331 (22%), Positives = 140/331 (42%), Gaps = 38/331 (11%)
Query: 56 TSTELLKVLNRIWSLEEQHSSNISLIKALKTELDRTRIKVKELLRDRQADRHEVDDLMKQ 115
T T+L R+ LE Q + L +L + ++ R ++ EV+ L KQ
Sbjct: 906 TKTQLSDAEERLAKLEAQQKDASKQLSELNDQLADNEDRTADVQRAKKKIEAEVEALKKQ 965
Query: 116 IAE-DKLVRK--SKEQDRLHAAVQSVRDELEDE-------RKLRKRSESIHRKLAREL-- 163
I + + +RK S++Q + H ++S++DE++ + K +K E I+RKL +L
Sbjct: 966 IQDLEMSLRKAESEKQSKDH-QIRSLQDEMQQQDEAIAKLNKEKKHQEEINRKLMEDLQS 1024
Query: 164 --------SEMKSSFTSALKDLEQERTRRKLLEDLCDEFARGINEYEQEVHTLKQKSEKD 215
+++K+ L DLE R K D+ R + E E+ ++ ++
Sbjct: 1025 EEDKGNHQNKVKAKLEQTLDDLEDSLEREKRARADLDKQKRKV---EGELKIAQENIDES 1081
Query: 216 WVQRADHDRLV------LHISESWLDERMQMQLEAAQNGFMDKNSIVDKLSLEIETFIKA 269
QR D + + LH S L++ Q + Q D S + +L E+E ++
Sbjct: 1082 GRQRHDLENNLKKKESELHSVSSRLEDE-QALVSKLQRQIKDGQSRISELEEELENERQS 1140
Query: 270 KQNSRSAENQVIRDRRNSLESVPLNDAVSAPQAMGDDDDDDSVGS---DSHCFELNKPSH 326
+ + A++ + R+ E + +A Q + + + D +N +
Sbjct: 1141 RSKADRAKSDLQRELEELGEKLDEQGGATAAQVEVNKKREAELAKLRRDLEEANMNHENQ 1200
Query: 327 MGA--KVHKEEI--LDKNLDETSKSNVKKKK 353
+G K H + + L LD+ +K+ K +K
Sbjct: 1201 LGGLRKKHTDAVAELTDQLDQLNKAKAKVEK 1231
Score = 54.3 bits (129), Expect = 1e-06
Identities = 66/329 (20%), Positives = 142/329 (43%), Gaps = 58/329 (17%)
Query: 70 LEEQHSSNISLIKALKTELDRTRIKVKELLRDRQADRHEVDDLMKQIA--EDKLVRKSKE 127
L E+ +S + +++ KT+L ++ +L ++ ++ +L Q+A ED+ +
Sbjct: 892 LVEEKTSLFTNLESTKTQLSDAEERLAKLEAQQKDASKQLSELNDQLADNEDRTADVQRA 951
Query: 128 QDRLHAAVQSVRDELED-ERKLRKRSESIH------RKLARELSEMKSSFTSALKDLE-Q 179
+ ++ A V++++ +++D E LRK R L E+ + + K+ + Q
Sbjct: 952 KKKIEAEVEALKKQIQDLEMSLRKAESEKQSKDHQIRSLQDEMQQQDEAIAKLNKEKKHQ 1011
Query: 180 ERTRRKLLEDLCDEFARGINE------YEQEVHTLKQKSEKDWVQRADHDRL------VL 227
E RKL+EDL E +G ++ EQ + L+ E++ RAD D+ L
Sbjct: 1012 EEINRKLMEDLQSEEDKGNHQNKVKAKLEQTLDDLEDSLEREKRARADLDKQKRKVEGEL 1071
Query: 228 HISESWLDE-------------RMQMQLEAAQNGFMDKNSIVDKLS----------LEIE 264
I++ +DE + + +L + + D+ ++V KL E+E
Sbjct: 1072 KIAQENIDESGRQRHDLENNLKKKESELHSVSSRLEDEQALVSKLQRQIKDGQSRISELE 1131
Query: 265 TFIKAKQNSRSAENQVIRDRRNSLESVPLNDAVSAPQAMGDDDDDDSVGSDSHCFELNKP 324
++ ++ SRS ++ D + LE + + D+ G+ + E+NK
Sbjct: 1132 EELENERQSRSKADRAKSDLQRELEEL-------------GEKLDEQGGATAAQVEVNKK 1178
Query: 325 SHMGAKVHKEEILDKNLDETSKSNVKKKK 353
+ ++ + N++ ++ +KK
Sbjct: 1179 REAELAKLRRDLEEANMNHENQLGGLRKK 1207
Score = 38.1 bits (87), Expect = 0.076
Identities = 44/218 (20%), Positives = 94/218 (42%), Gaps = 17/218 (7%)
Query: 87 ELDRTRIKVKELLRDRQADRHEVDDLMKQIAEDKLVRKSKEQDRL-HAAVQSVRDELEDE 145
E R R ++ L+ ++++ H V ++ E LV K + Q + + + + +ELE+E
Sbjct: 1080 ESGRQRHDLENNLKKKESELHSVSSRLED--EQALVSKLQRQIKDGQSRISELEEELENE 1137
Query: 146 RKLRKRSESIHRKLARELSEMKSSFT----SALKDLEQERTRRKLLEDLCDEFARGINEY 201
R+ R +++ L REL E+ + +E + R L L + +
Sbjct: 1138 RQSRSKADRAKSDLQRELEELGEKLDEQGGATAAQVEVNKKREAELAKLRRDLEEANMNH 1197
Query: 202 EQEVHTLKQKSEKDWVQRADH-DRLVLHISESWLD--------ERMQMQLEAAQNGFMDK 252
E ++ L++K + D D+L ++ D E + QL+ +G ++
Sbjct: 1198 ENQLGGLRKKHTDAVAELTDQLDQLNKAKAKVEKDKAQAVRDAEDLAAQLDQETSGKLNN 1257
Query: 253 NSIVDKLSLEIETFIKAKQNSRSAENQVIRDRRNSLES 290
+ + L++ T +++K + +S + Q + L S
Sbjct: 1258 EKLAKQFELQL-TELQSKADEQSRQLQDFTSLKGRLHS 1294
Score = 33.5 bits (75), Expect = 1.9
Identities = 85/419 (20%), Positives = 162/419 (38%), Gaps = 66/419 (15%)
Query: 99 LRDRQADRHEVDDLMKQIAE--DKLVRKSKEQDRLHAAVQSVRDELEDERKLRKRSESIH 156
LR+ D + + +++AE + L R++K L ++ + D+L + + + I
Sbjct: 1486 LRNTSTDLFKAKNAQEELAEVVEGLRRENKS---LSQEIKDLTDQLGEGGRSVHEMQKII 1542
Query: 157 RKLARELSEMKSSFTSALKDLEQERTRRKLLEDLCDEFARGINEYEQEVHTLKQKSEKDW 216
R+L E E++ + A LE E + K+L + +++ E+ Q+ E+++
Sbjct: 1543 RRLEIEKEELQHALDEAEAALEAEES--KVLRAQVE-----VSQIRSEIEKRIQEKEEEF 1595
Query: 217 VQ-RADHDRLVLHISESWLDERMQMQLEAAQNGFMDKNSIVDKLSLEIETFIKAKQNSRS 275
R +H R + E MQ LE G + I KL +I A ++
Sbjct: 1596 ENTRKNHARAL---------ESMQASLETEAKGKAELLRIKKKLEGDINELEIALDHANK 1646
Query: 276 AENQVIRDRRNSLESV-PLNDAVSAPQAMGDDDDDDSVGSDSHCFELNKPSHMGAKVHKE 334
A ++ + E V L V Q G D + ++ L KE
Sbjct: 1647 ANADAQKNLKRYQEQVRELQLQVEEEQRNGADTREQFFNAEKRATLLQS--------EKE 1698
Query: 335 EILDKNLDETSKSNVKKKKSVPGEGFKNHIPSNSNKKSQSVDAE-EGLTTNIRLVEGTRI 393
E+L N ++ + +K E +++ ++ +A+ LT+ R +EG
Sbjct: 1699 ELLVAN-----EAAERARKQAEYEA------ADARDQANEANAQVSSLTSAKRKLEG--- 1744
Query: 394 SEEPEHFEISESGGFERKNNLSELHSTSKNHIIDNLIRGQLLASESGKNNKHAEHNNYGE 453
+ H ++ E+ N SK I D LA E + +H++H
Sbjct: 1745 EIQAIHADLDET-----LNEYKAAEERSKKAIAD----ATRLAEELRQEQEHSQH----- 1790
Query: 454 ASCSNAGWRNQASPVRQWMASLDISEASKVHSGSK---DNTLKAKLLEARSKGQRSRLR 509
G Q +++ LD +EA+ + G K + + LE+ G++ R +
Sbjct: 1791 VDRLRKGLEQQ---LKEIQVRLDEAEAAALKGGKKVIAKLEQRVRELESELDGEQRRFQ 1846
Score = 32.7 bits (73), Expect = 3.2
Identities = 72/365 (19%), Positives = 155/365 (41%), Gaps = 65/365 (17%)
Query: 65 NRIWSLEEQHSSNISLIKALKTELDRTRIKVKELLRDRQADRHEVDDLMKQIAEDKLVRK 124
N++ L ++H+ ++ + +L++ + KV+ +D+ + +DL Q+ ++ +
Sbjct: 1199 NQLGGLRKKHTDAVAELTDQLDQLNKAKAKVE---KDKAQAVRDAEDLAAQLDQETSGKL 1255
Query: 125 SKEQ-----DRLHAAVQSVRDE----LEDERKLRKRSESIHRKLARELSEMKSSFTSALK 175
+ E+ + +QS DE L+D L+ R S + L R+L + +S
Sbjct: 1256 NNEKLAKQFELQLTELQSKADEQSRQLQDFTSLKGRLHSENGDLVRQLEDAESQVN---- 1311
Query: 176 DLEQERTRRKLLEDLCDEFARGINEYEQEVHTLKQKSEKDWVQRADHDRLVLHISESWLD 235
+ R + +L L +E R +E +E T+ ++ K++ A+ L
Sbjct: 1312 --QLTRLKSQLTSQL-EEARRTADEEARERQTVAAQA-KNYQHEAEQ-----------LQ 1356
Query: 236 ERMQMQLEAAQNGFMDKNSIVDKLS------------LEIETFIKAK--QNSRSAENQVI 281
E ++ ++E KN I+ +LS E E +KA ++++ + Q I
Sbjct: 1357 ESLEEEIEG-------KNEILRQLSKANADIQQWKARFEGEGLLKADELEDAKRRQAQKI 1409
Query: 282 RDRRNSLESVPLNDAVSAPQAMGDDDDDDSVGS-DSHCFELNKPSHMGAKVHKEEI-LDK 339
+ + +L DA ++ A + VG D ++ + + + + + K++ DK
Sbjct: 1410 NELQEAL------DAANSKNASLEKTKSRLVGDLDDAQVDVERANGVASALEKKQKGFDK 1463
Query: 340 NLDETSKSNVKKKKSVPGEGFKNHIPSNSNKKSQSVDAEEGLTTNIRLVEGTRISEEPEH 399
+DE K + +G + + + S ++ +A+E L +VEG R +
Sbjct: 1464 IIDEWRKKTDDLAAEL--DGAQRDLRNTSTDLFKAKNAQEELA---EVVEGLRRENKSLS 1518
Query: 400 FEISE 404
EI +
Sbjct: 1519 QEIKD 1523
>MYHB_RABIT (P35748) Myosin heavy chain, smooth muscle isoform (SMMHC)
Length = 1972
Score = 55.5 bits (132), Expect = 5e-07
Identities = 97/429 (22%), Positives = 170/429 (39%), Gaps = 62/429 (14%)
Query: 46 RIGEPHYSLKTSTELLKVLNRIWSLEEQHSSNISLIKALKTELDRTRIKVKELLRDRQ-- 103
RI + +L E K L + L+ +H S IS ++ + +++R ++++L R
Sbjct: 1007 RISDLTTNLAEEEEKAKNLTK---LKNKHESMISELEVRLKKEEKSRQELEKLKRKMDGE 1063
Query: 104 -ADRHE-VDDLMKQIAEDKLVRKSKEQDRLHAAVQSVRDELEDERKLRKRSESIHRKLAR 161
+D HE + DL QIAE K+ + +K+++ L AA+ + DE + K+
Sbjct: 1064 ASDLHEQIADLQAQIAELKM-QLAKKEEELQAALARLEDETSQKNNALKK---------- 1112
Query: 162 ELSEMKSSFTSALKDLEQERTRRKLLE----DLCDEFARGINEYEQEVHTLKQKSEKDWV 217
+ E++ + +DL+ ER R E DL +E E E + T + E
Sbjct: 1113 -IRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDTTATQQEL--- 1168
Query: 218 QRADHDRLVLHISESWLDERMQMQLEAAQNGFMDKNSIVDKLSLEIETFIKAKQN----- 272
RA ++ V + ++ LDE + Q +V++L+ ++E F +AK N
Sbjct: 1169 -RAKREQEVTVLKKA-LDEETRSHEAQVQEMRQKHTQVVEELTEQLEQFKRAKANLDKTK 1226
Query: 273 --------SRSAENQVIRDRRNSLESVPLNDAVSAPQAMGDDDDDDSVGSDSHCFELNKP 324
+ E +V+ + +E V + D + + ELN
Sbjct: 1227 QTLEKENADLAGELRVLGQAKQEVEHKKKKLEVQLQELQSKCSDGERARA-----ELNDK 1281
Query: 325 SHMGAKVHKE-EILDKNLDETSKSNVKKKKSVPGEGFKNHIPSNSNKKSQSVDAEEGLTT 383
H K+ E E + L E +K K V G + + + + ++T
Sbjct: 1282 VH---KLQNEVESVTGMLSEAEGKAIKLAKEVASLG--SQLQDTQELLQEETRQKLNVST 1336
Query: 384 NIRLVEGTRISEEPEHFEISESGGFERKNNLSELHSTSKNHIIDNLIRGQLLAS-----E 438
+R +E R S + + E E K NL ST + D+ + Q AS E
Sbjct: 1337 KLRQLEDERNSLQEQLDE-----EMEAKQNLERHISTLNIQLSDSKKKLQDFASTVESLE 1391
Query: 439 SGKNNKHAE 447
GK E
Sbjct: 1392 EGKKRFQKE 1400
Score = 50.4 bits (119), Expect = 1e-05
Identities = 91/479 (18%), Positives = 188/479 (38%), Gaps = 51/479 (10%)
Query: 69 SLEEQHSSNISLIKALKTELDRTRIKVKELLRDRQADRHEVDDLMKQIAEDK-----LVR 123
SLEE I++L + + +L + + + E+DDL+ + + L +
Sbjct: 1389 SLEEGKKRFQKEIESLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEK 1448
Query: 124 KSKEQDRLHAAVQSVRDELEDERKLRKRSESIHRKLARELSEMKSSFTSALKDLEQ-ERT 182
K K+ D+L A +++ + DE R R+E+ R+ + + + AL+ E+ ERT
Sbjct: 1449 KQKKFDQLLAEEKNISSKYADE---RDRAEAEAREKETKALSLARALEEALEAKEELERT 1505
Query: 183 RRKL---LEDLC---DEFARGINEYEQEVHTLKQKSE---------KDWVQRADHDRLVL 227
+ L +EDL D+ + ++E E+ L+ + E +D +Q + +L L
Sbjct: 1506 NKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRL 1565
Query: 228 HISESWLDERMQMQLEAAQNGFMDKNSIVDKLSLEIETFIKAKQNSRSAENQVIRDRRNS 287
++ L + + L+A +K + + E ET ++ ++ R+ +
Sbjct: 1566 EVNMQALKVQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGD 1625
Query: 288 LESVPL--NDAVSAP----------QAMGDD---DDDDSVGSDSHCFELNKPSHMGAKVH 332
L+ + L + A+ QA D + +D+ S F K + AK
Sbjct: 1626 LKDLELQADSAIKGREEAIKQLLKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSL 1685
Query: 333 KEEILDKNLDETSKSNVKKKKSVPGEGFKNHIPSNSNKKSQSVDAEEGLTTNIRLVEGTR 392
+ +++ D + +K+ + E + S+ + ++ D + L I +
Sbjct: 1686 EADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARI-----AQ 1740
Query: 393 ISEEPEHFEISESGGFERKNNLSELHSTSKNHIIDNLIRGQLLASESGKNNKHAEHNNYG 452
+ EE E E G E ++ + + + L + A ++ + E N
Sbjct: 1741 LEEELE----EEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKE 1796
Query: 453 EASCSNAGWRNQASPVRQWMASLDISEA---SKVHSGSKDNTLKAKLLEARSKGQRSRL 508
S S + +A+L+ A +V +++ AK L+ R K + L
Sbjct: 1797 LKSKLQEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAAAKALKQRDKKLKEML 1855
Score = 40.0 bits (92), Expect = 0.020
Identities = 100/502 (19%), Positives = 189/502 (36%), Gaps = 94/502 (18%)
Query: 72 EQHSSNISLIKALKTELDRTRIKVKELLRDRQAD-----------RHEVDDLMKQIAEDK 120
E+ + + K K LD+T K+ L AD + EV+ K++
Sbjct: 1206 EELTEQLEQFKRAKANLDKT----KQTLEKENADLAGELRVLGQAKQEVEHKKKKLEVQL 1261
Query: 121 LVRKSKEQD------RLHAAVQSVRDELEDERKLRKRSESIHRKLARELSEMKSSFTSAL 174
+SK D L+ V +++E+E + +E KLA+E++ + S
Sbjct: 1262 QELQSKCSDGERARAELNDKVHKLQNEVESVTGMLSEAEGKAIKLAKEVASLGSQLQDT- 1320
Query: 175 KDLEQERTRRKL---------------LEDLCDEFARGINEYEQEVHTLKQKSEKDWVQR 219
++L QE TR+KL L++ DE E+ + TL + +
Sbjct: 1321 QELLQEETRQKLNVSTKLRQLEDERNSLQEQLDEEMEAKQNLERHISTLNIQLSDSKKKL 1380
Query: 220 ADHDRLVLHISESWLDERMQMQLEAAQNGFMDKNSIVDK-------LSLEIETFIKAKQN 272
D V + E +R Q ++E+ + +K + DK L E++ + N
Sbjct: 1381 QDFASTVESLEEG--KKRFQKEIESLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDN 1438
Query: 273 SRS----------------AENQVI-------RDRRNSLESVPLNDAVSAPQAMGDDDDD 309
R AE + I RDR + A+S +A+ +
Sbjct: 1439 QRQLVSNLEKKQKKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARAL-----E 1493
Query: 310 DSVGSDSHCFELNK--PSHMGAKVHKEEILDKNLDETSKSNVKKKKSVPGEGFKNHIPSN 367
+++ + NK + M V ++ + KN+ E KS K+ E K +
Sbjct: 1494 EALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKS--KRALETQMEEMKTQLEEL 1551
Query: 368 SNKKSQSVDAEEGLTTNIRLVEGTRISEEPEHFEISESGGFERKNNLSELHSTSKNHIID 427
++ + DA+ L N ++ ++ E + E +R+ +LH + + D
Sbjct: 1552 EDELQATEDAKLRLEVN---MQALKVQFERDLQARDEQNEEKRRQLQRQLHE-YETELED 1607
Query: 428 NLIRGQLLASESGKNNKHAEHNNYGEASCSNAGWRNQA--------SPVRQWMASLDISE 479
R Q + + K + + + S R +A + ++ + L+ +
Sbjct: 1608 E--RKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLLKLQAQMKDFQRELEDAR 1665
Query: 480 ASK--VHSGSKDNTLKAKLLEA 499
AS+ + + +K+N KAK LEA
Sbjct: 1666 ASRDEIFATAKENEKKAKSLEA 1687
Score = 36.2 bits (82), Expect = 0.29
Identities = 55/308 (17%), Positives = 126/308 (40%), Gaps = 54/308 (17%)
Query: 59 ELLKVLNRIWSLEEQHSSNISLIKALKTELDRTRIKVKELLRDRQADRHEV-------DD 111
EL ++L+ + + E+ ++A + ++ + + ++E L + +A R ++ +
Sbjct: 919 ELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEA 978
Query: 112 LMKQIAEDKLV------RKSKEQDRLHAAVQSVRDELEDERKLRKRSESIHRKLARELSE 165
+K++ +D LV + SKE+ L + + L +E + K + K +SE
Sbjct: 979 KIKKLEDDILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISE 1038
Query: 166 MKSSFTSALKDLEQERTRRKLLEDLCDEFARGINEYEQEVHTLKQKSEKDWVQRADHDRL 225
++ K ++ ++ ++ + I + + ++ LK + K
Sbjct: 1039 LEVRLKKEEKSRQELEKLKRKMDGEASDLHEQIADLQAQIAELKMQLAKK---------- 1088
Query: 226 VLHISESWLDERMQMQLEAAQNGFMDKNSIVDKLSLEIETFIKAKQ----NSRSAENQVI 281
+E +Q L ++ KN+ + K+ E+E I Q + R+A N+
Sbjct: 1089 ---------EEELQAALARLEDETSQKNNALKKIR-ELEGHISDLQEDLDSERAARNKAE 1138
Query: 282 RDRRNSLESVPLNDAVSAPQAMGDDDDDDSVGSDSHCFELNKPSHMGAKVHKE-EILDKN 340
+ +R+ L + + A + +D D + + AK +E +L K
Sbjct: 1139 KQKRD------LGEELEALKTELEDTLDTTA----------TQQELRAKREQEVTVLKKA 1182
Query: 341 LDETSKSN 348
LDE ++S+
Sbjct: 1183 LDEETRSH 1190
Score = 35.8 bits (81), Expect = 0.38
Identities = 51/241 (21%), Positives = 111/241 (45%), Gaps = 23/241 (9%)
Query: 82 KALKTELDRTRIKVKELLRDRQADRHEVDDLMKQIAEDKLVRKS--KEQDRLHAAVQSVR 139
K+L+ +L + + + R R+ E ++L +++A R + E+ RL A + +
Sbjct: 1683 KSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLE 1742
Query: 140 DELEDE-----------RKLRKRSESIHRKLARELSEMKSSFTSALKDLEQE--RTRRKL 186
+ELE+E RK +++E + +LA E S + + SA + LE++ + KL
Sbjct: 1743 EELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKN-ESARQQLERQNKELKSKL 1801
Query: 187 LE---DLCDEFARGINEYEQEVHTLKQKSEKDWVQRADHDRLVLHISESWLDERMQMQLE 243
E + +F I E ++ L+++ E++ ++ + + + + M +Q+E
Sbjct: 1802 QEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAAAKALKQRDKKL--KEMLLQVE 1859
Query: 244 AAQNGFMDKNSIVDKLSLEIETFIKAKQNSRSAENQVIRDRRNSLESVPLNDAVSAPQAM 303
+ +K + +++ +K + E+Q I R L+ L++A + +AM
Sbjct: 1860 DERKMAEQYKEQAEKGNAKVKQ-LKRQLEEAEEESQRINANRRKLQR-ELDEATESNEAM 1917
Query: 304 G 304
G
Sbjct: 1918 G 1918
Score = 35.0 bits (79), Expect = 0.65
Identities = 29/136 (21%), Positives = 66/136 (48%), Gaps = 9/136 (6%)
Query: 82 KALKTELDR----TRIKVKELLRDRQADRHEVDDLMKQIAEDK--LVRKSKEQDRLHAAV 135
K LK++L + K K + +A ++++ ++Q A +K + K++D+ +
Sbjct: 1795 KELKSKLQEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAAAKALKQRDK---KL 1851
Query: 136 QSVRDELEDERKLRKRSESIHRKLARELSEMKSSFTSALKDLEQERTRRKLLEDLCDEFA 195
+ + ++EDERK+ ++ + K ++ ++K A ++ ++ R+ L+ DE
Sbjct: 1852 KEMLLQVEDERKMAEQYKEQAEKGNAKVKQLKRQLEEAEEESQRINANRRKLQRELDEAT 1911
Query: 196 RGINEYEQEVHTLKQK 211
+EV+ LK K
Sbjct: 1912 ESNEAMGREVNALKSK 1927
Score = 34.7 bits (78), Expect = 0.84
Identities = 44/200 (22%), Positives = 87/200 (43%), Gaps = 33/200 (16%)
Query: 94 KVKELLRDRQADRHEVDDLMKQIAEDKLVRKSKEQDRLHAAVQSVRD---ELEDERKLRK 150
KVK LL Q R E + Q ED+L + + Q + + +Q ++ +L +E+ L +
Sbjct: 840 KVKPLL---QVTRQEEE---MQAKEDELQKIKERQQKAESELQELQQKHTQLSEEKNLLQ 893
Query: 151 RSESIHRKLARELSEMKSSFTSALKDLEQERTRRKLLEDLCDEFARGINEYEQEVHTLKQ 210
+L E EM+ + +++ LE++ E + E E L+
Sbjct: 894 EQLQAETELYAEAEEMRVRLAA----------KKQELEEILHEMEARLEEEEDRGQQLQA 943
Query: 211 KSEKDWVQRADHDRLVLHISESWLDERMQMQLEAAQNGFMDKNSIVDKL-SLEIETFIKA 269
+ +K Q D L+E+++ + A Q ++K + K+ LE + +
Sbjct: 944 ERKKMAQQMLD------------LEEQLEEEEAARQKLQLEKVTAEAKIKKLEDDILVMD 991
Query: 270 KQNSR-SAENQVIRDRRNSL 288
QN++ S E +++ +R + L
Sbjct: 992 DQNNKLSKERKLLEERISDL 1011
Score = 33.9 bits (76), Expect = 1.4
Identities = 31/105 (29%), Positives = 51/105 (48%), Gaps = 14/105 (13%)
Query: 66 RIWSLEEQHSSNISLIKALKTELDRTRIKVKELLRDRQADRHEVDDLMKQIAEDKLVRKS 125
+I LEEQ +A L + K+KE+L +V+D E K+ +
Sbjct: 1822 KIAQLEEQVEQEAREKQAAAKALKQRDKKLKEMLL-------QVED------ERKMAEQY 1868
Query: 126 KEQ-DRLHAAVQSVRDELEDERKLRKRSESIHRKLARELSEMKSS 169
KEQ ++ +A V+ ++ +LE+ + +R + RKL REL E S
Sbjct: 1869 KEQAEKGNAKVKQLKRQLEEAEEESQRINANRRKLQRELDEATES 1913
>EEA1_HUMAN (Q15075) Early endosome antigen 1 (Endosome-associated
protein p162) (Zinc finger FYVE domain containing
protein 2)
Length = 1411
Score = 55.5 bits (132), Expect = 5e-07
Identities = 85/461 (18%), Positives = 190/461 (40%), Gaps = 91/461 (19%)
Query: 41 LDFKGRIGEPHYSLKTSTELL--KVLNR----------IWSLEEQHSSNISLIKALKTEL 88
L+ + ++GE H LK +L K++++ + LEEQ ++ L+ +L
Sbjct: 424 LETERQLGEAHGRLKEQRQLSSEKLMDKEQQVADLQLKLSRLEEQLKEKVTNSTELQHQL 483
Query: 89 DRTRIKVKELLRDRQAD-------RHEVDDLMKQIAE--------DKLVRKSKE------ 127
D+T+ + +E +Q+ +++++ +++QI + + L++KSKE
Sbjct: 484 DKTKQQHQEQQALQQSTTAKLREAQNDLEQVLRQIGDKDQKIQNLEALLQKSKENISLLE 543
Query: 128 --QDRLHAAVQSVRDELEDERKLRKRSESIHRK---LARELSEMKSSFTSALKDL----E 178
++ L+A +Q+ E +L++++ ++ + L +L S A ++L +
Sbjct: 544 KEREDLYAKIQAGEGETAVLNQLQEKNHTLQEQVTQLTEKLKNQSESHKQAQENLHDQVQ 603
Query: 179 QERTRRKLLEDLCDEFARGINEYEQEVHTLKQKSEKDWVQRADHDRLVLHISESWLDERM 238
+++ + +D +NE +++ K+K + +Q L+L + +R
Sbjct: 604 EQKAHLRAAQDRVLSLETSVNELNSQLNESKEKVSQLDIQIKAKTELLLSAEAAKTAQRA 663
Query: 239 QMQ--LEAAQNGFMDKNSIVDKLSLEI-------------------------ETFIKAKQ 271
+Q L+ AQN DK ++K++ ++ E ++ +Q
Sbjct: 664 DLQNHLDTAQNALQDKQQELNKITTQLDQVTAKLQDKQEHCSQLESHLKEYKEKYLSLEQ 723
Query: 272 NSRSAENQVIRDRRNSLESVPLNDAVSAPQAMGDDDDDDSVGSD--SHCFELNKPSHMGA 329
+ E Q+ LE+ L S QA+ D + +D EL+K M
Sbjct: 724 KTEELEGQI-----KKLEADSLEVKASKEQALQDLQQQRQLNTDLELRATELSKQLEMEK 778
Query: 330 KVHKEEILDKNLDETSKSNVKKK-------KSVPGEGFKNHIPSNSNKKSQSVDAEEGLT 382
++ LD + ++K+K K + + F+ + K Q + +
Sbjct: 779 EIVSSTRLDLQKKSEALESIKQKLTKQEEEKQILKQDFET---LSQETKIQHEELNNRIQ 835
Query: 383 TNIRLVEGTRISEEPEHFEISESGGFERKNNLSELHSTSKN 423
T + ++ ++ +E E+S K+ LS++ + KN
Sbjct: 836 TTVTELQKVKMEKEALMTELSTV-----KDKLSKVSDSLKN 871
Score = 46.2 bits (108), Expect = 3e-04
Identities = 74/382 (19%), Positives = 163/382 (42%), Gaps = 67/382 (17%)
Query: 38 NSSL-DFKGRIGEPHYSLKTSTELLKVLNRIWSLEEQHSSNISLIKALKTELDRTRIKVK 96
NS L + K ++ + +K TELL S + A + +L +
Sbjct: 627 NSQLNESKEKVSQLDIQIKAKTELLL-------------SAEAAKTAQRADLQNHLDTAQ 673
Query: 97 ELLRDRQADRHEVDDLMKQIAEDKLVRKSKEQDRLHAAVQSVRDELEDERKLRKRSESIH 156
L+D+Q + +++ + Q+ KL K + +L + ++ +++ + + E
Sbjct: 674 NALQDKQQELNKITTQLDQVTA-KLQDKQEHCSQLESHLKEYKEKYLSLEQKTEELEGQI 732
Query: 157 RKLARELSEMKSSFTSALKDLEQERTRRKLLEDLCDEFARGINEYEQEVHT-----LKQK 211
+KL + E+K+S AL+DL+Q+R LE E ++ + E E+E+ + L++K
Sbjct: 733 KKLEADSLEVKASKEQALQDLQQQRQLNTDLELRATELSKQL-EMEKEIVSSTRLDLQKK 791
Query: 212 SE-----KDWVQRADHDRLVL-----------HISESWLDERMQMQLEAAQNGFMDKNSI 255
SE K + + + ++ +L I L+ R+Q + Q M+K ++
Sbjct: 792 SEALESIKQKLTKQEEEKQILKQDFETLSQETKIQHEELNNRIQTTVTELQKVKMEKEAL 851
Query: 256 VDKLSL------EIETFIKAKQNSRSAENQ-----------VIRDRRNSLESVPLNDAVS 298
+ +LS ++ +K ++ ENQ ++ ++ L+ V + + +
Sbjct: 852 MTELSTVKDKLSKVSDSLKNSKSEFEKENQKGKAAILDLEKTCKELKHQLQ-VQMENTLK 910
Query: 299 APQAMGDDDDDDSVGSDSHCFELNKPSHMGAKVHKEEILDKNLDETSKSNVKKKKSVPGE 358
+ + + + S ELN +E+++ T K N K+++ + +
Sbjct: 911 EQKELKKSLEKEKEASHQLKLELNS--------MQEQLI--QAQNTLKQNEKEEQQL--Q 958
Query: 359 GFKNHIPSNSNKKSQSVDAEEG 380
G N + +S +K + ++A +G
Sbjct: 959 GNINELKQSSEQKKKQIEALQG 980
Score = 39.3 bits (90), Expect = 0.034
Identities = 75/403 (18%), Positives = 154/403 (37%), Gaps = 74/403 (18%)
Query: 118 EDKLVRKSKEQDRLHAAVQSVRDELEDER----KLRKRSESIHRKLARE------LSEMK 167
E L K + L VQ ++ L++E+ +L+K E +E +++
Sbjct: 75 ESNLALKRDDVTLLRQEVQDLQASLKEEKWYSEELKKELEKYQGLQQQEAKPDGLVTDSS 134
Query: 168 SSFTSALKDLEQERTRRKLLEDLCDEFARGINEYEQEVHTLKQKSEKDWVQRADHDRLVL 227
+ S + LE+ +T ++ + D F + + E+ +K K +++ R ++ V
Sbjct: 135 AELQSLEQQLEEAQTENFNIKQMKDLFEQKAAQLATEIADIKSKYDEERSLREAAEQKVT 194
Query: 228 HISESWLDER---MQMQLEAAQNGFMDKNSIVDKLSLEIETFIKAKQNSRSAENQVIRDR 284
++E E ++ E Q ++ +++ K ++++T + R E++ ++D
Sbjct: 195 RLTEELNKEATVIQDLKTELLQRPGIEDVAVLKKELVQVQTLMDNMTLERERESEKLKDE 254
Query: 285 RNSLESVPLNDAVSAPQAMGDDDDDDSVGSDSHCFELNK-PSHMGAKVHKEEILDKNLDE 343
L+S + + Q EL K P + V + + L +++E
Sbjct: 255 CKKLQSQYASSEATISQLRS---------------ELAKGPQEVAVYVQELQKLKSSVNE 299
Query: 344 TSKSNVKKKKSVPGEGFKNHIPSNSNKKSQSVDAEEGLTTNIRLVEGTRISEEPEHFEIS 403
++ N + LT N+ E E +H E S
Sbjct: 300 LTQKN------------------------------QTLTENLLKKEQDYTKLEEKHNEES 329
Query: 404 ESGGFERKNNLSELHSTSKNHIIDNLIRGQLLASESGKNNKHAEHNNYGEA--------S 455
S +KN + LH + + ++ +L ASE+ + H E + GEA S
Sbjct: 330 VS----KKNIQATLH---QKDLDCQQLQSRLSASETSLHRIHVELSEKGEATQKLKEELS 382
Query: 456 CSNAGWRNQASPVRQWMASLDISEASKVHSGSKDNTLKAKLLE 498
+++ + +Q + E + S+ N L +KLLE
Sbjct: 383 EVETKYQHLKAEFKQLQQQREEKEQHGLQLQSEINQLHSKLLE 425
>MYHA_BOVIN (Q27991) Myosin heavy chain, nonmuscle type B (Cellular
myosin heavy chain, type B) (Nonmuscle myosin heavy
chain-B) (NMMHC-B)
Length = 1976
Score = 54.7 bits (130), Expect = 8e-07
Identities = 69/374 (18%), Positives = 149/374 (39%), Gaps = 38/374 (10%)
Query: 64 LNRIWSLEEQHSSNISLIKALKTELDRTRIKVKELLRDRQADRHEVDDLMKQIAEDK--- 120
L I +LEE + ++ L L+ + +L + + + E+DDL+ + +
Sbjct: 1384 LGTIENLEEAKKKLLKDVEVLSQRLEEKALAYDKLEKTKTRLQQELDDLLVDLDHQRQIV 1443
Query: 121 --LVRKSKEQDRLHAAVQSVRDELEDERKL----RKRSESIHRKLARELSEMKSSFTSAL 174
L +K K+ D+L A +++ +ER + E+ LAR L E + A
Sbjct: 1444 SNLEKKQKKFDQLLAEEKNISARYAEERDRAEAEAREKETKALSLARALEEALEAREEAE 1503
Query: 175 KDLEQERTRRKLLEDLCDEFARGINEYEQEVHTLKQKSE---------KDWVQRADHDRL 225
+ +Q R + L D+ + ++E E+ L+Q+ E +D +Q + +L
Sbjct: 1504 RQNKQLRADMEDLMSSKDDVGKNVHELEKSKRALEQQVEEMRTQLEELEDELQATEDAKL 1563
Query: 226 VLHISESWLDERMQMQLEAAQNGFMDKNSIVDKLSLEIETFIKAKQNSRSAENQVIRDRR 285
L ++ + + + L+ +K ++ K E+E ++ ++ R+ V ++
Sbjct: 1564 RLEVNMQAMKAQFERDLQTRDEQNEEKKRLLIKQVRELEAELEDERKQRAL--AVASKKK 1621
Query: 286 NSLESVPLNDAVSAPQAMGDD-----------------DDDDSVGSDSHCFELNKPSHMG 328
++ L + A D+ + +++ S F +K S
Sbjct: 1622 MEIDLKDLEAQIEAANKARDEVIKQLRKLQAQMKDYQRELEEARASRDEIFAQSKESEKK 1681
Query: 329 AKVHKEEILDKNLDETSKSNVKKKKSVPGEGFKNHIPSNSNKKSQSVDAEEGLTTNIRLV 388
K + EIL + S ++ + + I ++++ KS +D + L I +
Sbjct: 1682 LKSLEAEILQLQEELASSERARRHAEQERDELADEIANSASGKSALLDEKRRLEARIAQL 1741
Query: 389 EGTRISEEPEHFEI 402
E + EE + E+
Sbjct: 1742 E-EELEEEQSNMEL 1754
Score = 43.9 bits (102), Expect = 0.001
Identities = 51/253 (20%), Positives = 115/253 (45%), Gaps = 27/253 (10%)
Query: 82 KALKTELDRTRIKVKELLRDRQAD-----RHEVD--DLMKQIAEDKLVRKSKEQDRLHAA 134
+AL+ +++ R +++EL + QA R EV+ + Q D R + +++
Sbjct: 1535 RALEQQVEEMRTQLEELEDELQATEDAKLRLEVNMQAMKAQFERDLQTRDEQNEEKKRLL 1594
Query: 135 VQSVRD---ELEDERKLRKRSESIHRKLARELSEMKSSFTSALKDLEQERTRRKLLEDLC 191
++ VR+ ELEDERK R + + +K+ +L ++++ +A K ++ + + L+
Sbjct: 1595 IKQVRELEAELEDERKQRALAVASKKKMEIDLKDLEAQIEAANKARDEVIKQLRKLQAQM 1654
Query: 192 DEFARGINEYEQEVHTLKQKSEKDWVQRADHDRLVLHISESWL-DERMQMQLEAAQNGFM 250
++ R + E + +S++ + + +L + E ER + E ++
Sbjct: 1655 KDYQRELEEARASRDEIFAQSKESEKKLKSLEAEILQLQEELASSERARRHAEQERDELA 1714
Query: 251 DK--NSIVDKLSL------------EIETFIKAKQNSRSAENQVIRDRRNSLESVPLNDA 296
D+ NS K +L ++E ++ +Q++ N R R+ +L+ LN
Sbjct: 1715 DEIANSASGKSALLDEKRRLEARIAQLEEELEEEQSNMELLND--RFRKTTLQVDTLNTE 1772
Query: 297 VSAPQAMGDDDDD 309
++A ++ D+
Sbjct: 1773 LAAERSAAQKSDN 1785
Score = 42.4 bits (98), Expect = 0.004
Identities = 51/245 (20%), Positives = 109/245 (43%), Gaps = 35/245 (14%)
Query: 34 AATPNSSLDFKGRIGEPHYSLKTSTELLKVLNRIWS--------LEEQHSSNISL----- 80
A+ +D K + + K E++K L ++ + LEE +S +
Sbjct: 1617 ASKKKMEIDLKDLEAQIEAANKARDEVIKQLRKLQAQMKDYQRELEEARASRDEIFAQSK 1676
Query: 81 -----IKALKTELDRTRIKVKELLRDRQADRHEVDDLMKQIAEDKLVRKS--KEQDRLHA 133
+K+L+ E+ + + ++ R R+ E D+L +IA + + E+ RL A
Sbjct: 1677 ESEKKLKSLEAEILQLQEELASSERARRHAEQERDELADEIANSASGKSALLDEKRRLEA 1736
Query: 134 AVQSVRDELEDE-----------RKLRKRSESIHRKLARELSEMKSSFTSALKDLEQERT 182
+ + +ELE+E RK + ++++ +LA E S + S + + Q +
Sbjct: 1737 RIAQLEEELEEEQSNMELLNDRFRKTTLQVDTLNTELAAERSAAQKSDNARQQLERQNKE 1796
Query: 183 RRKLLEDL----CDEFARGINEYEQEVHTLKQKSEKDWVQRADHDRLVLHISESWLDERM 238
+ L++L +F I+ E ++ L+++ E++ +RA ++LV + + M
Sbjct: 1797 LKAKLQELEGAVKSKFKATISALEAKIGQLEEQLEQEAKERAAANKLVRRTEKKLKEIFM 1856
Query: 239 QMQLE 243
Q++ E
Sbjct: 1857 QVEDE 1861
Score = 41.6 bits (96), Expect = 0.007
Identities = 43/209 (20%), Positives = 88/209 (41%), Gaps = 24/209 (11%)
Query: 93 IKVKELLRDRQADRHEVDDLMKQIAEDKLVRKS--KEQDRLHAAVQSVRDELEDERKLRK 150
IK K+L+ DR A+ Q+AE++ K+ K +++ + + + L+ E K R+
Sbjct: 998 IKEKKLMEDRIAE------CSSQLAEEEEKAKNLAKIRNKQEVMISDLEERLKKEEKTRQ 1051
Query: 151 RSESIHRKLARELSEMKSSFTSALKDLEQERTR-RKLLEDLCDEFARG------------ 197
E RKL E ++++ +++ + + K E+L ARG
Sbjct: 1052 ELEKAKRKLDGETTDLQDQIAELQAQIDELKIQVAKKEEELQGALARGDDETLHKNNALK 1111
Query: 198 -INEYEQEVHTLKQKSEKDWVQRADHDRLVLHISESWLDERMQMQLEAAQNGFMDKNSIV 256
+ E + ++ L++ E + R ++ +SE E ++ +LE + + +
Sbjct: 1112 VVRELQAQIAELQEDFESEKASRNKAEKQKRDLSEEL--EALKTELEDTLDTTAAQQELR 1169
Query: 257 DKLSLEIETFIKAKQNSRSAENQVIRDRR 285
K E+ KA + + I+D R
Sbjct: 1170 TKREQEVAELKKALEEETKSHEAQIQDMR 1198
Score = 36.6 bits (83), Expect = 0.22
Identities = 75/374 (20%), Positives = 151/374 (40%), Gaps = 56/374 (14%)
Query: 44 KGRIGEPHYSLKTSTELLKVLNRIWSLEEQHSSNISLIKALKTELD-----RTRIKVKEL 98
K + E + L++ E + N+I L+ + + I+ L+ +LD R +++++++
Sbjct: 917 KQELEEILHDLESRVEEEEERNQI--LQNEKKKMQAHIQDLEEQLDEEEGARQKLQLEKV 974
Query: 99 LRDRQADRHEVDDLMKQIAEDKLVRKSKEQDRLHAAVQSVRDELEDERKLRKRSESIHRK 158
+ + + E + L+ ED+ + KE+ + + +L +E + K I K
Sbjct: 975 TAEAKIKKMEEEILL---LEDQNSKFIKEKKLMEDRIAECSSQLAEEEEKAKNLAKIRNK 1031
Query: 159 LARELSEMKSSFTSALKDLEQ-ERTRRKL---LEDLCDEFARGINEYEQEVHTLKQKSEK 214
+S+++ K ++ E+ +RKL DL D+ A E + ++ LK + K
Sbjct: 1032 QEVMISDLEERLKKEEKTRQELEKAKRKLDGETTDLQDQIA----ELQAQIDELKIQVAK 1087
Query: 215 DWVQRADHDRLVLHISESWLDERMQMQLEAAQNGFMDKNS---IVDKLSLEI----ETFI 267
+E +Q L + + KN+ +V +L +I E F
Sbjct: 1088 K-------------------EEELQGALARGDDETLHKNNALKVVRELQAQIAELQEDFE 1128
Query: 268 KAKQNSRSAENQVIRDRRNSLESV--PLNDAVSAPQAMGDDDDDDSVGSDSHCFELNKPS 325
K + AE Q RD LE++ L D + A + + EL K
Sbjct: 1129 SEKASRNKAEKQK-RDLSEELEALKTELEDTLDTTAA----QQELRTKREQEVAELKKAL 1183
Query: 326 HMGAKVHKEEILDKNLDETSKSNVKKKKSVPGEGFKNHIPSNSNKKSQSVDAEEGLTTNI 385
K H+ +I D + ++ + FK ++ NK+ D +E L +
Sbjct: 1184 EEETKSHEAQIQDMRQRHATALEELSEQLEQAKRFKANL--EKNKQGLETDNKE-LACEV 1240
Query: 386 RLVEGTRISEEPEH 399
++++ ++ E EH
Sbjct: 1241 KVLQ--QVKAESEH 1252
Score = 35.8 bits (81), Expect = 0.38
Identities = 74/383 (19%), Positives = 156/383 (40%), Gaps = 63/383 (16%)
Query: 43 FKGRIGEPHYSLKTSTELL----KVLNRIWSLEEQHS-----SNISLIKALKTELDRTRI 93
FK + + L+T + L KVL ++ E +H + + + A +E DR R+
Sbjct: 1218 FKANLEKNKQGLETDNKELACEVKVLQQV-KAESEHKRKKLDAQVQELHAKVSEGDRLRV 1276
Query: 94 KVKELLRDRQADRHEVDDLMKQIAEDKLVRKSKEQDRLHAAVQSVRDELEDERKLRKRSE 153
++ E Q + V L+++ AE K ++ +K+ L + +Q ++ L++E +
Sbjct: 1277 ELAEKANKLQNELDNVSTLLEE-AEKKGIKFAKDAAGLESQLQDTQELLQEETR------ 1329
Query: 154 SIHRKLARELSEMKSSFTSALKDLEQERT------------RRKL---LEDLCDEFARGI 198
K + +S ++ LE+ER+ RR L L+ L +
Sbjct: 1330 ------------QKLNLSSRIRQLEEERSSLQEQQEEEEEARRSLEKQLQALQAQLTDTK 1377
Query: 199 NEYEQEVHTLKQKSEKDWVQRADHDRLVLHISESWL--------DERMQMQLEAAQNGFM 250
+ + ++ T++ E D + L + E L R+Q +L+
Sbjct: 1378 KKVDDDLGTIENLEEAKKKLLKDVEVLSQRLEEKALAYDKLEKTKTRLQQELDDLLVDLD 1437
Query: 251 DKNSIVDKLSLEIETF--IKAKQNSRSAENQVIRDRRNSLESVPLNDAVSAPQAMGDDDD 308
+ IV L + + F + A++ + SA RDR + A+S +A+
Sbjct: 1438 HQRQIVSNLEKKQKKFDQLLAEEKNISARYAEERDRAEAEAREKETKALSLARAL----- 1492
Query: 309 DDSVGSDSHCFELNKP--SHMGAKVHKEEILDKNLDETSKSNVKKKKSVPGEGFKNHIPS 366
++++ + NK + M + ++ + KN+ E KS ++ V E + +
Sbjct: 1493 EEALEAREEAERQNKQLRADMEDLMSSKDDVGKNVHELEKSKRALEQQV--EEMRTQLEE 1550
Query: 367 NSNKKSQSVDAEEGLTTNIRLVE 389
++ + DA+ L N++ ++
Sbjct: 1551 LEDELQATEDAKLRLEVNMQAMK 1573
Score = 34.7 bits (78), Expect = 0.84
Identities = 24/100 (24%), Positives = 45/100 (45%), Gaps = 12/100 (12%)
Query: 66 RIWSLEEQHSSNISLIKALKTELDRTRIKVKELLRDRQADRHEVDDLMKQIAEDKLVRKS 125
+I LEEQ A + RT K+KE+ + +R D +Q+
Sbjct: 1822 KIGQLEEQLEQEAKERAAANKLVRRTEKKLKEIFMQVEDERRHADQYKEQM--------- 1872
Query: 126 KEQDRLHAAVQSVRDELEDERKLRKRSESIHRKLARELSE 165
++ +A ++ ++ +LE+ + R+ + RKL REL +
Sbjct: 1873 ---EKANARMKQLKRQLEEAEEEATRANASRRKLQRELDD 1909
Score = 32.7 bits (73), Expect = 3.2
Identities = 36/139 (25%), Positives = 69/139 (48%), Gaps = 16/139 (11%)
Query: 81 IKALKTELD-RTRIKVKELLRDRQADRHEVDDLMKQIAED-----KLVRKS-KEQDRLHA 133
+KA EL+ + K K + +A ++++ ++Q A++ KLVR++ K+ +
Sbjct: 1797 LKAKLQELEGAVKSKFKATISALEAKIGQLEEQLEQEAKERAAANKLVRRTEKKLKEIFM 1856
Query: 134 AVQSVRDELEDERKLRKRSESIHRKLARELSEMKSSFTSALKDLEQERTRRKLLEDLCDE 193
V+ R + ++ +++ + ++L R+L E + T A +RRKL +L D
Sbjct: 1857 QVEDERRHADQYKEQMEKANARMKQLKRQLEEAEEEATRA------NASRRKLQRELDD- 1909
Query: 194 FARGINE-YEQEVHTLKQK 211
A NE +EV TLK +
Sbjct: 1910 -ATEANEGLSREVSTLKNR 1927
>USO1_YEAST (P25386) Intracellular protein transport protein USO1
Length = 1790
Score = 54.3 bits (129), Expect = 1e-06
Identities = 61/243 (25%), Positives = 115/243 (47%), Gaps = 22/243 (9%)
Query: 54 LKTSTELLKVL-NRIWSLEEQHSSNISLIKALKTELDRTRIKVKELLRDRQADRHEVDDL 112
L+ S E++K L + I S E + S++ I+ +L++++ +E +++ Q HE DL
Sbjct: 1500 LEKSKEMMKKLESTIESNETELKSSMETIRKSDEKLEQSKKSAEEDIKNLQ---HEKSDL 1556
Query: 113 MKQIAE-DKLVRKSKEQDRLHAAVQSVRDELEDERKLRKRSESIHRKLARELSEMKSSFT 171
+ +I E +K + + K + R+ A S ELE ++ ++ R A E + +KS
Sbjct: 1557 ISRINESEKDIEELKSKLRIEAKSGS---ELETVKQELNNAQEKIRINAEENTVLKSKLE 1613
Query: 172 SALKDLEQERTRRKLLEDLCDEFARGINEYEQEVHTLKQKSEKDWVQRADHDRLVLHISE 231
++L+ ++ K ++ + + E EQE+ + +QK++K +R R + +
Sbjct: 1614 DIERELKDKQAEIKSNQEEKELLTSRLKELEQELDSTQQKAQKSEEERRAEVR-KFQVEK 1672
Query: 232 SWLDERMQMQLEAAQNGFMDK-----------NSIVDKLSLEIETFIKAKQNSRSAENQV 280
S LDE+ M LE N ++K D EIE K N + AEN
Sbjct: 1673 SQLDEK-AMLLETKYNDLVNKEQAWKRDEDTVKKTTDSQRQEIEKLAKELDNLK-AENSK 1730
Query: 281 IRD 283
+++
Sbjct: 1731 LKE 1733
Score = 48.9 bits (115), Expect = 4e-05
Identities = 66/324 (20%), Positives = 131/324 (40%), Gaps = 61/324 (18%)
Query: 65 NRIWSLEEQHSSNISLIKALKTELDRTRIKVKELLRDRQADRHEVDDLMKQIAEDKLVRK 124
+ I S +++ + N + +++ + R +KE LR Q + +V++ +K++ E+ K
Sbjct: 1438 DEILSYKDKITRNDEKLLSIERDNKRDLESLKEQLRAAQESKAKVEEGLKKLEEESSKEK 1497
Query: 125 SKEQDRLHAAVQSVRDELEDERKLRKRSESIHRKLARELSEMKSSFTSALKDLEQERTRR 184
+ E ++ ++ + +E K S RK +L + K S +K+L+ E++
Sbjct: 1498 A-ELEKSKEMMKKLESTIESNETELKSSMETIRKSDEKLEQSKKSAEEDIKNLQHEKS-- 1554
Query: 185 KLLEDLCDEFARGINEYEQEVHTLKQK--------SEKDWVQRA---DHDRLVLHISESW 233
+ INE E+++ LK K SE + V++ +++ ++ E+
Sbjct: 1555 --------DLISRINESEKDIEELKSKLRIEAKSGSELETVKQELNNAQEKIRINAEENT 1606
Query: 234 LDERMQMQLEAAQNGFMDKN--------------SIVDKLSLEIETFIKAKQNSRSAENQ 279
+ ++ +LE + DK S + +L E+++ + Q S
Sbjct: 1607 V---LKSKLEDIERELKDKQAEIKSNQEEKELLTSRLKELEQELDSTQQKAQKSEEERRA 1663
Query: 280 VIR---------DRRNSLESVPLNDAVSAPQAMGDDDDDDSVGSDSHCFELNKPSHMGAK 330
+R D + L ND V+ QA D+D +DS E+ K
Sbjct: 1664 EVRKFQVEKSQLDEKAMLLETKYNDLVNKEQAWKRDEDTVKKTTDSQRQEIEK------- 1716
Query: 331 VHKEEILDKNLDETSKSNVKKKKS 354
L K LD N K K++
Sbjct: 1717 ------LAKELDNLKAENSKLKEA 1734
Score = 47.8 bits (112), Expect = 1e-04
Identities = 63/294 (21%), Positives = 143/294 (48%), Gaps = 36/294 (12%)
Query: 85 KTELDRTRIKVKELLRDRQADRHEVDDLMKQIAEDKLVRKSKEQDRLHAAVQSVRDELED 144
K+E+D +++KEL + + + + + +K + E + V+ + QD + + V ELED
Sbjct: 1222 KSEIDALNLQIKELKKKNETNEASLLESIKSV-ESETVKIKELQDECNFKEKEV-SELED 1279
Query: 145 ERKLRKRSESIHRKLARELSEMKSSFTSALKDLEQERTRRKLLEDLCDEFARGINEYEQE 204
+ K + S + +L +E ++K ++L+ + T K+ + ++ + E E
Sbjct: 1280 KLKASEDKNSKYLELQKESEKIK-------EELDAKTTELKIQLEKITNLSKAKEKSESE 1332
Query: 205 VHTLKQKS---EKDWVQRADHDRLVLHISESWLDERMQMQLEAAQ---NGFMDK-NSIVD 257
+ LK+ S K+ ++ + + + I ++ ++ E + + +K N++ D
Sbjct: 1333 LSRLKKTSSEERKNAEEQLEKLKNEIQIKNQAFEKERKLLNEGSSTITQEYSEKINTLED 1392
Query: 258 KL-SLEIETFIKAKQ--NSRS-------AENQVIRDRRNSLESVPLNDAVSAPQAMGDDD 307
+L L+ E +KAK+ N+RS + ++++ +++N+++S+ ++ +S + +D
Sbjct: 1393 ELIRLQNENELKAKEIDNTRSELEKVSLSNDELLEEKQNTIKSLQ-DEILSYKDKITRND 1451
Query: 308 D-------DDSVGSDSHCFELNKPSHMGAKVHKEEILDKNLDETSKSNVKKKKS 354
+ D+ +S +L AKV EE L K +E+SK + +KS
Sbjct: 1452 EKLLSIERDNKRDLESLKEQLRAAQESKAKV--EEGLKKLEEESSKEKAELEKS 1503
Score = 45.8 bits (107), Expect = 4e-04
Identities = 70/353 (19%), Positives = 142/353 (39%), Gaps = 51/353 (14%)
Query: 70 LEEQHSSNISLIKALKTELDRTRIKVKELLRDRQADRHEVDDLMKQIAEDKLVRKSKEQD 129
LE + N + + K+ + + +K L + + + K+ AED + + K+
Sbjct: 816 LETKDKENQTALLEYKSTIHKQEDSIKTLEKGLETILSQ-----KKKAEDGINKMGKDLF 870
Query: 130 RLHAAVQSVRDELEDERKLRKRSESIHRKLARELSEMKSSFTSALKDLEQERTRRKLLED 189
L +Q+V + ++ +K + +S H+K + L E D+ + T K + +
Sbjct: 871 ALSREMQAVEENCKNLQKEKDKSNVNHQKETKSLKE----------DIAAKITEIKAINE 920
Query: 190 LCDEFARGINEYEQEVHTLKQKSEKDWVQRADHDRLVLHISESWLDERMQMQLEAAQNGF 249
+E N +E + ++ + + HD LV ++E +L++ N +
Sbjct: 921 NLEEMKIQCNNLSKEKEHISKELVEYKSRFQSHDNLVAKLTE---------KLKSLANNY 971
Query: 250 MDKNSIVDKLSLEIETFIKAKQNSRSAENQVIRDRRNSLESVPLNDAVSAPQAMGDDDDD 309
D + E E+ IKA + S++ + + + +N ++S M + ++
Sbjct: 972 KD-------MQAENESLIKAVEESKNESSIQLSNLQNKIDS------------MSQEKEN 1012
Query: 310 DSV--GSDSHCFELNKPSHMGAKVHKEEILDKNLDETSKSNVKKKKSVPGEGFKNHIPSN 367
+ GS E K + + KEEI+ K+ ++SK + + S+ E + +N
Sbjct: 1013 FQIERGSIEKNIEQLKKTISDLEQTKEEIISKS--DSSKDEYESQISLLKEKLETATTAN 1070
Query: 368 S---NKKSQSVDAEEGLTTNIRLVEGTRISEEPEHFEISESGGFERKNNLSEL 417
NK S+ E L + + + +E E SE E K N L
Sbjct: 1071 DENVNKISELTKTREELEAELAAYKNLK-NELETKLETSEKALKEVKENEEHL 1122
Score = 45.4 bits (106), Expect = 5e-04
Identities = 87/485 (17%), Positives = 200/485 (40%), Gaps = 55/485 (11%)
Query: 55 KTSTELLKVLN----RIWSLEEQHSSNISLIKALKTELDRTRIKVKELLRDRQADRHEVD 110
K +TE + LN + SLE++H + +K + ++ ++RQ + E+
Sbjct: 1131 KEATETKQQLNSLRANLESLEKEHEDLAAQLKKYEEQIAN---------KERQYNE-EIS 1180
Query: 111 DLMKQIAEDKLVRKS--KEQDRLHAAVQSVRDELEDERKLRKRSESIHRKLARELSEM-- 166
L +I + +S K+ D L V++++ E++ L+K +EL +
Sbjct: 1181 QLNDEITSTQQENESIKKKNDELEGEVKAMKSTSEEQSNLKKSEIDALNLQIKELKKKNE 1240
Query: 167 --KSSFTSALKDLEQERTRRKLLEDLCDEFARGINEYEQEVHTLKQKSEKDWVQRADHDR 224
++S ++K +E E + K L+D C+ + ++E E ++ + K+ K + + ++
Sbjct: 1241 TNEASLLESIKSVESETVKIKELQDECNFKEKEVSELEDKLKASEDKNSKYLELQKESEK 1300
Query: 225 LVLHISESWLDERMQMQ----LEAAQNGFMDKNSIVDKLSLE----IETFIKAKQNSRSA 276
+ + + ++Q++ L A+ + S + K S E E ++ +N
Sbjct: 1301 IKEELDAKTTELKIQLEKITNLSKAKEKSESELSRLKKTSSEERKNAEEQLEKLKNEIQI 1360
Query: 277 ENQVIRDRRNSLESVPLNDAVSAPQAMGDDDDDDSVGSDSHCFELNKPSHMGAKVHKEEI 336
+NQ R L + + +D+ + + + + + +++ K +
Sbjct: 1361 KNQAFEKERKLLNEGSSTITQEYSEKINTLEDELIRLQNENELKAKEIDNTRSELEKVSL 1420
Query: 337 LDKNLDETSKSNVKKKKSVPGE--GFKNHIPSNSNKKSQSVDAE-----EGLTTNIRLVE 389
+ L E ++ + KS+ E +K+ I N ++K S++ + E L +R +
Sbjct: 1421 SNDELLEEKQNTI---KSLQDEILSYKDKITRN-DEKLLSIERDNKRDLESLKEQLRAAQ 1476
Query: 390 GTRISEEPEHFEISESGGFER------KNNLSELHSTSKNH------IIDNLIRGQLLAS 437
++ E ++ E E+ K + +L ST +++ ++ + +
Sbjct: 1477 ESKAKVEEGLKKLEEESSKEKAELEKSKEMMKKLESTIESNETELKSSMETIRKSDEKLE 1536
Query: 438 ESGKNNKHAEHNNYGEASCSNAGWRNQASPVRQWMASLDISEASKVHSGSKDNTLKAKLL 497
+S K+ + N E S + + + + L I + SGS+ T+K +L
Sbjct: 1537 QSKKSAEEDIKNLQHEKSDLISRINESEKDIEELKSKLRI----EAKSGSELETVKQELN 1592
Query: 498 EARSK 502
A+ K
Sbjct: 1593 NAQEK 1597
>MYHB_HUMAN (P35749) Myosin heavy chain, smooth muscle isoform (SMMHC)
Length = 1972
Score = 53.9 bits (128), Expect = 1e-06
Identities = 99/479 (20%), Positives = 194/479 (39%), Gaps = 79/479 (16%)
Query: 46 RIGEPHYSLKTSTELLKVLNRIWSLEEQHSSNISLIKALKTELDRTRIKVKELLRDRQAD 105
RI + +L E K L + L+ +H S IS ++ + +++R ++++L R + D
Sbjct: 1007 RISDLTTNLAEEEEKAKNLTK---LKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGD 1063
Query: 106 ----RHEVDDLMKQIAEDKLVRKSKEQD-----------------------RLHAAVQSV 138
++ DL QIAE K+ KE++ L + +
Sbjct: 1064 ASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDL 1123
Query: 139 RDELEDERKLRKRSESIHRKLARELSEMKSSFTSALKDLEQERTRRKLLEDLCDEFARGI 198
+++L+ ER R ++E R L EL +K+ L ++ R E + +
Sbjct: 1124 QEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKAL 1183
Query: 199 NE----YEQEVHTLKQK---------SEKDWVQRA----DHDRLVLHISESWLDERMQMQ 241
+E +E +V ++QK + + +RA D ++ L + L +++
Sbjct: 1184 DEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVL 1243
Query: 242 LEAAQNGFMDKNSIVDKLSLEIETFIKAKQNSRSAENQVIRDRRNSLESVP--LNDAVSA 299
+A Q K + ++ E+++ + +R+ N + +N +ESV LN+A
Sbjct: 1244 GQAKQEVEHKKKKLEAQVQ-ELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGK 1302
Query: 300 PQAMGDD--------DDDDSVGSDSHCFELNKPSHMGAKVHKEEILDKNLDET--SKSNV 349
+ D D + + +LN + + + L LDE +K N+
Sbjct: 1303 AIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNL 1362
Query: 350 KKKKSVPGEGFKNHIPSNSNKKSQ----SVDA-EEGLTTNIRLVEGT--RISEEPEHFEI 402
++ S N S+S KK Q +V+A EEG + +E + E+ ++
Sbjct: 1363 ERHIST-----LNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDK 1417
Query: 403 SESGGFERKNNLSEL--HSTSKNHIIDNLIR-----GQLLASESGKNNKHAEHNNYGEA 454
E + L +L ++ ++ NL + QLLA E ++K+A+ + EA
Sbjct: 1418 LEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEA 1476
Score = 45.8 bits (107), Expect = 4e-04
Identities = 50/236 (21%), Positives = 104/236 (43%), Gaps = 27/236 (11%)
Query: 82 KALKTELDRTRIKVKELLRDRQAD-----RHEVD--DLMKQIAEDKLVRKSKEQDR---L 131
+AL+T+++ + +++EL + QA R EV+ L Q D R + +++ L
Sbjct: 1535 RALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQL 1594
Query: 132 HAAVQSVRDELEDERKLRKRSESIHRKLARELSEMKSSFTSALKDLEQERTRRKLLEDLC 191
+ ELEDERK R + + +KL +L +++ SA+K E+ + + L+
Sbjct: 1595 QRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQM 1654
Query: 192 DEFARGINE---YEQEVHTLKQKSEK-------DWVQ------RADHDRLVLHISESWLD 235
+F R + + E+ +++EK D +Q A+ R + + L
Sbjct: 1655 KDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELA 1714
Query: 236 ERMQMQLEAAQNGFMDKNSIVDKLSLEIETFIKAKQNSRSAENQVIRDRRNSLESV 291
E + L + +N D+ ++ ++E ++ +Q + A + +R E +
Sbjct: 1715 EELASSL-SGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQL 1769
Score = 40.4 bits (93), Expect = 0.015
Identities = 64/369 (17%), Positives = 144/369 (38%), Gaps = 40/369 (10%)
Query: 69 SLEEQHSSNISLIKALKTELDRTRIKVKELLRDRQADRHEVDDLMKQIAEDK-----LVR 123
+LEE I+ L + + +L + + + E+DDL+ + + L +
Sbjct: 1389 ALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEK 1448
Query: 124 KSKEQDRLHAAVQSVRDELEDERKLRKRSESIHRKLARELSEMKSSFTSALKDLEQERTR 183
K ++ D+L A +++ + DER R+E+ R+ + + + AL+ E+
Sbjct: 1449 KQRKFDQLLAEEKNISSKYADERD---RAEAEAREKETKALSLARALEEALEAKEELERT 1505
Query: 184 RKLLEDLCDEFARGINEYEQEVHTLKQKSE----------------KDWVQRADHDRLVL 227
K+L+ ++ ++ + VH L++ +D +Q + +L L
Sbjct: 1506 NKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRL 1565
Query: 228 HISESWLDERMQMQLEAAQNGFMDKNSIVDKLSLEIETFIKAKQNSRSAENQVIRDRRNS 287
++ L + + L+A +K + + E ET ++ ++ R+ +
Sbjct: 1566 EVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGD 1625
Query: 288 LESVPL--NDAVSAP----------QAMGDD---DDDDSVGSDSHCFELNKPSHMGAKVH 332
L+ + L + A+ QA D + +D+ S F K + AK
Sbjct: 1626 LKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSL 1685
Query: 333 KEEILDKNLDETSKSNVKKKKSVPGEGFKNHIPSNSNKKSQSVDAEEGLTTNIRLVEGTR 392
+ +++ D + +K+ + E + S+ + ++ D + L I +E
Sbjct: 1686 EADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLE-EE 1744
Query: 393 ISEEPEHFE 401
+ EE + E
Sbjct: 1745 LEEEQGNME 1753
Score = 39.3 bits (90), Expect = 0.034
Identities = 61/309 (19%), Positives = 129/309 (41%), Gaps = 56/309 (18%)
Query: 59 ELLKVLNRIWSLEEQHSSNISLIKALKTELDRTRIKVKELLRDRQADRHEV-------DD 111
EL ++L+ + + E+ ++A + ++ + + ++E L + +A R ++ +
Sbjct: 919 ELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEA 978
Query: 112 LMKQIAEDKLV------RKSKEQDRLHAAVQSVRDELEDERKLRKRSESIHRKLARELSE 165
+K++ ++ LV + SKE+ L + + L +E + K + K +SE
Sbjct: 979 KIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISE 1038
Query: 166 MKSSFTSALKDLEQ-ERTRRKLLEDLCDEFARGINEYEQEVHTLKQKSEKDWVQRADHDR 224
++ K ++ E+ +RKL D D F I + + ++ LK + K
Sbjct: 1039 LEVRLKKEEKSRQELEKLKRKLEGDASD-FHEQIADLQAQIAELKMQLAKK--------- 1088
Query: 225 LVLHISESWLDERMQMQLEAAQNGFMDKNSIVDKLSLEIETFIKAKQ----NSRSAENQV 280
+E +Q L + KN+ + K+ E+E I Q + R+A N+
Sbjct: 1089 ----------EEELQAALARLDDEIAQKNNALKKIR-ELEGHISDLQEDLDSERAARNKA 1137
Query: 281 IRDRRNSLESVPLNDAVSAPQAMGDDDDDDSVGSDSHCFELNKPSHMGAKVHKE-EILDK 339
+ +R+ L + + A + +D D + + AK +E +L K
Sbjct: 1138 EKQKRD------LGEELEALKTELEDTLDSTA----------TQQELRAKREQEVTVLKK 1181
Query: 340 NLDETSKSN 348
LDE ++S+
Sbjct: 1182 ALDEETRSH 1190
Score = 38.9 bits (89), Expect = 0.045
Identities = 48/224 (21%), Positives = 99/224 (43%), Gaps = 24/224 (10%)
Query: 61 LKVLNRIWSLEEQHSSNISLIKALKTELDRTRIKVKELLRDRQADRHEVDDLMKQI---- 116
+K L ++ EE+ + ++ K + ++KEL + E + L +Q+
Sbjct: 841 VKPLLQVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAET 900
Query: 117 -----AEDKLVRKSKEQDRLHAAVQSVRDELEDERKLRKRSESIHRKLARELSEMKSSFT 171
AE+ VR + ++ L + + LE+E ++ ++ +K+A+++ +++
Sbjct: 901 ELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLE 960
Query: 172 SALKDLEQERTRRKL-LEDLCDEFARGINEYEQEVHTLKQKSEKDWVQRADHDRLVLHIS 230
E+E R+KL LE + E I + E E+ + ++ K +R +L
Sbjct: 961 ------EEEAARQKLQLEKVTAE--AKIKKLEDEILVMDDQNNK-----LSKERKLLEER 1007
Query: 231 ESWLDERMQMQLEAAQNGFMDKNSIVDKLSLEIETFIKAKQNSR 274
S L + + E A+N KN +S E+E +K ++ SR
Sbjct: 1008 ISDLTTNLAEEEEKAKNLTKLKNKHESMIS-ELEVRLKKEEKSR 1050
Score = 37.0 bits (84), Expect = 0.17
Identities = 59/250 (23%), Positives = 112/250 (44%), Gaps = 41/250 (16%)
Query: 82 KALKTELDRTRIKVKELLRDRQADRHEVDDLMKQIAEDKLVRKS--KEQDRLHAAVQSVR 139
K+L+ +L + + + R R+ E ++L +++A R + E+ RL A + +
Sbjct: 1683 KSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLE 1742
Query: 140 DELEDE-----------RKLRKRSESIHRKLARELSEMKSSFTSALKDLEQE--RTRRKL 186
+ELE+E RK +++E + +LA E S + + SA + LE++ R KL
Sbjct: 1743 EELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKN-ESARQQLERQNKELRSKL 1801
Query: 187 LE---DLCDEFARGINEYEQEVHTLKQKSEKDWVQR-------ADHDRLVLHISESWLDE 236
E + +F I E ++ L+++ E++ ++ D+ + I DE
Sbjct: 1802 HEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDE 1861
Query: 237 R--MQMQLEAAQNGFMDKNSIVDKLSLEIETFIKAKQNSRSAENQVIRDRRNSLESVPLN 294
R + E A+ G N+ V +L ++E E+Q I R L+ L+
Sbjct: 1862 RKMAEQYKEQAEKG----NARVKQLKRQLE--------EAEEESQRINANRRKLQR-ELD 1908
Query: 295 DAVSAPQAMG 304
+A + +AMG
Sbjct: 1909 EATESNEAMG 1918
Score = 34.3 bits (77), Expect = 1.1
Identities = 25/120 (20%), Positives = 58/120 (47%), Gaps = 5/120 (4%)
Query: 94 KVKELLRDRQADRHEVDDLMKQIAEDK--LVRKSKEQDRLHAAVQSVRDELEDERKLRKR 151
K K + +A ++++ ++Q A +K + K++D+ ++ + ++EDERK+ ++
Sbjct: 1811 KFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDK---KLKEILLQVEDERKMAEQ 1867
Query: 152 SESIHRKLARELSEMKSSFTSALKDLEQERTRRKLLEDLCDEFARGINEYEQEVHTLKQK 211
+ K + ++K A ++ ++ R+ L+ DE +EV+ LK K
Sbjct: 1868 YKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSK 1927
Score = 34.3 bits (77), Expect = 1.1
Identities = 31/105 (29%), Positives = 51/105 (48%), Gaps = 14/105 (13%)
Query: 66 RIWSLEEQHSSNISLIKALKTELDRTRIKVKELLRDRQADRHEVDDLMKQIAEDKLVRKS 125
+I LEEQ +A L + K+KE+L +V+D E K+ +
Sbjct: 1822 KIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILL-------QVED------ERKMAEQY 1868
Query: 126 KEQ-DRLHAAVQSVRDELEDERKLRKRSESIHRKLARELSEMKSS 169
KEQ ++ +A V+ ++ +LE+ + +R + RKL REL E S
Sbjct: 1869 KEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRELDEATES 1913
>MYHA_RAT (Q9JLT0) Myosin heavy chain, nonmuscle type B (Cellular
myosin heavy chain, type B) (Nonmuscle myosin heavy
chain-B) (NMMHC-B)
Length = 1976
Score = 53.5 bits (127), Expect = 2e-06
Identities = 74/378 (19%), Positives = 156/378 (40%), Gaps = 46/378 (12%)
Query: 64 LNRIWSLEEQHSSNISLIKALKTELDRTRIKVKELLRDRQADRHEVDDL------MKQIA 117
L I LEE + ++AL L+ + +L + + + E+DDL +QI
Sbjct: 1384 LGTIEGLEEAKKKLLKDVEALSQRLEEKVLAYDKLEKTKNRLQQELDDLTVDLDHQRQIV 1443
Query: 118 EDKLVRKSKEQDRLHAAVQSVRDELEDERKLRKRSESIHRKLARELSEMKSSFTSALKDL 177
+ L +K K+ D+L A + + +E R R+E+ R+ + + + AL+
Sbjct: 1444 SN-LEKKQKKFDQLLAEEKGISARYAEE---RDRAEAEAREKETKALSLARALEEALEAK 1499
Query: 178 EQ-ERTRRKL---LEDLC---DEFARGINEYEQEVHTLKQKSE---------KDWVQRAD 221
E+ ER ++L +EDL D+ + ++E E+ L+Q+ E +D +Q +
Sbjct: 1500 EEFERQNKQLRADMEDLMSSKDDVGKNVHELEKSKRALEQQVEEMRTQLEELEDELQATE 1559
Query: 222 HDRLVLHISESWLDERMQMQLEAAQNGFMDKNSIVDKLSLEIETFIKAKQNSRSAENQVI 281
+L L ++ + + + L+ +K ++ K E+E ++ ++ R+ V
Sbjct: 1560 DAKLRLEVNMQAMKAQFERDLQTRDEQNEEKKRLLLKQVRELEAELEDERKQRAL--AVA 1617
Query: 282 RDRRNSLESVPLNDAVSAPQAMGDD-----------------DDDDSVGSDSHCFELNKP 324
++ ++ L + A D+ + +++ S F +K
Sbjct: 1618 SKKKMEIDLKDLEAQIEAANKARDEVIKQLRKLQAQMKDYQRELEEARASRDEIFAQSKE 1677
Query: 325 SHMGAKVHKEEILDKNLDETSKSNVKKKKSVPGEGFKNHIPSNSNKKSQSVDAEEGLTTN 384
S K + EIL + S ++ + + I ++++ KS +D + L
Sbjct: 1678 SEKKLKSLEAEILQLQEELASSERARRHAEQERDELADEIANSASGKSALLDEKRRLEAR 1737
Query: 385 IRLVEGTRISEEPEHFEI 402
I +E + EE + E+
Sbjct: 1738 IAQLE-EELEEEQSNMEL 1754
Score = 43.1 bits (100), Expect = 0.002
Identities = 51/253 (20%), Positives = 115/253 (45%), Gaps = 27/253 (10%)
Query: 82 KALKTELDRTRIKVKELLRDRQAD-----RHEVD--DLMKQIAEDKLVRKSKEQDRLHAA 134
+AL+ +++ R +++EL + QA R EV+ + Q D R + +++
Sbjct: 1535 RALEQQVEEMRTQLEELEDELQATEDAKLRLEVNMQAMKAQFERDLQTRDEQNEEKKRLL 1594
Query: 135 VQSVRD---ELEDERKLRKRSESIHRKLARELSEMKSSFTSALKDLEQERTRRKLLEDLC 191
++ VR+ ELEDERK R + + +K+ +L ++++ +A K ++ + + L+
Sbjct: 1595 LKQVRELEAELEDERKQRALAVASKKKMEIDLKDLEAQIEAANKARDEVIKQLRKLQAQM 1654
Query: 192 DEFARGINEYEQEVHTLKQKSEKDWVQRADHDRLVLHISESWL-DERMQMQLEAAQNGFM 250
++ R + E + +S++ + + +L + E ER + E ++
Sbjct: 1655 KDYQRELEEARASRDEIFAQSKESEKKLKSLEAEILQLQEELASSERARRHAEQERDELA 1714
Query: 251 DK--NSIVDKLSL------------EIETFIKAKQNSRSAENQVIRDRRNSLESVPLNDA 296
D+ NS K +L ++E ++ +Q++ N R R+ +L+ LN
Sbjct: 1715 DEIANSASGKSALLDEKRRLEARIAQLEEELEEEQSNMELLND--RFRKTTLQVDTLNTE 1772
Query: 297 VSAPQAMGDDDDD 309
++A ++ D+
Sbjct: 1773 LAAERSAAQKSDN 1785
Score = 42.4 bits (98), Expect = 0.004
Identities = 56/275 (20%), Positives = 111/275 (40%), Gaps = 33/275 (12%)
Query: 42 DFKGRI-GEPHYSLKTSTELLKVLNRIWSLEEQHSSNISLIKALKTELDRTRIKVKEL-- 98
D + R+ GE + E K+ I LEEQ + L+ E K+K++
Sbjct: 926 DLESRVEGEEERNQILQNEKKKMQAHIQDLEEQLDEEEGARQKLQLEKVTAEAKIKKMEE 985
Query: 99 ------------LRDRQADRHEVDDLMKQIAEDKLVRKS--KEQDRLHAAVQSVRDELED 144
+++++ + + Q+AE++ K+ K +++ + + + L+
Sbjct: 986 EVLLLEDQNSKFIKEKKLMEDRIAECSSQLAEEEEKAKNLAKIRNKQEVMISDLEERLKK 1045
Query: 145 ERKLRKRSESIHRKLARELSEMKSSFTSALKDLEQERTR-RKLLEDLCDEFARGINEYEQ 203
E K R+ E RKL E ++++ +++ + + K E+L ARG +E
Sbjct: 1046 EEKTRQELEKAKRKLDGETTDLQDQIAELQAQVDELKVQLTKKEEELQGALARGDDETLH 1105
Query: 204 EVHTLKQKSEKDWVQRADHDRLVLHISESWLD-ERMQMQLEAAQNGFMDKNSIVDKLSLE 262
+ + LK E L I+E D E + A+ D + ++ L E
Sbjct: 1106 KNNALKVARE-----------LQAQIAELQEDFESEKASRNKAEKQKRDLSEELEALKTE 1154
Query: 263 IETFI---KAKQNSRSAENQVIRDRRNSLESVPLN 294
+E + A+Q R+ Q + + + +LE N
Sbjct: 1155 LEDTLDTTAAQQELRTKREQEVAELKKALEDETKN 1189
Score = 42.4 bits (98), Expect = 0.004
Identities = 51/245 (20%), Positives = 109/245 (43%), Gaps = 35/245 (14%)
Query: 34 AATPNSSLDFKGRIGEPHYSLKTSTELLKVLNRIWS--------LEEQHSSNISL----- 80
A+ +D K + + K E++K L ++ + LEE +S +
Sbjct: 1617 ASKKKMEIDLKDLEAQIEAANKARDEVIKQLRKLQAQMKDYQRELEEARASRDEIFAQSK 1676
Query: 81 -----IKALKTELDRTRIKVKELLRDRQADRHEVDDLMKQIAEDKLVRKS--KEQDRLHA 133
+K+L+ E+ + + ++ R R+ E D+L +IA + + E+ RL A
Sbjct: 1677 ESEKKLKSLEAEILQLQEELASSERARRHAEQERDELADEIANSASGKSALLDEKRRLEA 1736
Query: 134 AVQSVRDELEDE-----------RKLRKRSESIHRKLARELSEMKSSFTSALKDLEQERT 182
+ + +ELE+E RK + ++++ +LA E S + S + + Q +
Sbjct: 1737 RIAQLEEELEEEQSNMELLNDRFRKTTLQVDTLNTELAAERSAAQKSDNARQQLERQNKE 1796
Query: 183 RRKLLEDL----CDEFARGINEYEQEVHTLKQKSEKDWVQRADHDRLVLHISESWLDERM 238
+ L++L +F I+ E ++ L+++ E++ +RA ++LV + + M
Sbjct: 1797 LKAKLQELEGAVKSKFKATISALEAKIGQLEEQLEQEAKERAAANKLVRRTEKKLKEIFM 1856
Query: 239 QMQLE 243
Q++ E
Sbjct: 1857 QVEDE 1861
Score = 41.6 bits (96), Expect = 0.007
Identities = 70/378 (18%), Positives = 149/378 (38%), Gaps = 32/378 (8%)
Query: 97 ELLRDRQADRHEVDDLMKQIAEDKLVRKSKEQDR--LHAAVQSVRDELEDERKLRKRSES 154
++ R+ QA ++ +L + +K R E+ + L +++++ ELED +
Sbjct: 1111 KVARELQA---QIAELQEDFESEKASRNKAEKQKRDLSEELEALKTELEDTLDTTAAQQE 1167
Query: 155 IHRKLARELSEMKSSFTSALKDLEQE-----RTRRKLLEDLCDEFARGINEYEQEVHTLK 209
+ K +E++E+K + K+ E + + LE+L ++ + ++ + K
Sbjct: 1168 LRTKREQEVAELKKALEDETKNHEAQIQDMRQRHATALEELSEQLEQA-KRFKANLEKNK 1226
Query: 210 QKSEKDWVQRADHDRLVLHISESWLDERMQMQLEAAQNGFMDKNSIVDKLSLEIETFIKA 269
Q E D + A +++ + E + +L+A K S D+L +E+
Sbjct: 1227 QGLETDNKELACEVKVLQQVKAE--SEHKRKKLDAQVQELHAKVSEGDRLRVELAEKANK 1284
Query: 270 KQNSRSAENQVIRDRRNSLESVPLNDAVSAPQAMGDDDDDDSVGSDSHCFELNKPSHMGA 329
QN + ++ + E + A A D + + +LN S +
Sbjct: 1285 LQNELDNVSTLLEE----AEKKGMKFAKDAAGLESQLQDTQELLQEETRQKLNLSSRIRQ 1340
Query: 330 KVHKEEILDKNLDETSKSNVKKKKSVPGEGFKNHIPSNSNKKSQSVDAEEGLTTNIR--L 387
++ L + +E ++ +K V ++ + K + EGL + L
Sbjct: 1341 LEEEKNSLQEQQEEEEEARKNLEKQV--LALQSQLADTKKKVDDDLGTIEGLEEAKKKLL 1398
Query: 388 VEGTRISEEPEHFEISESGGFERKNNLSE------LHSTSKNHIIDNLIR-----GQLLA 436
+ +S+ E ++ + KN L + + + I+ NL + QLLA
Sbjct: 1399 KDVEALSQRLEEKVLAYDKLEKTKNRLQQELDDLTVDLDHQRQIVSNLEKKQKKFDQLLA 1458
Query: 437 SESGKNNKHAEHNNYGEA 454
E G + ++AE + EA
Sbjct: 1459 EEKGISARYAEERDRAEA 1476
Score = 34.7 bits (78), Expect = 0.84
Identities = 24/100 (24%), Positives = 45/100 (45%), Gaps = 12/100 (12%)
Query: 66 RIWSLEEQHSSNISLIKALKTELDRTRIKVKELLRDRQADRHEVDDLMKQIAEDKLVRKS 125
+I LEEQ A + RT K+KE+ + +R D +Q+
Sbjct: 1822 KIGQLEEQLEQEAKERAAANKLVRRTEKKLKEIFMQVEDERRHADQYKEQM--------- 1872
Query: 126 KEQDRLHAAVQSVRDELEDERKLRKRSESIHRKLARELSE 165
++ +A ++ ++ +LE+ + R+ + RKL REL +
Sbjct: 1873 ---EKANARMKQLKRQLEEAEEEATRANASRRKLQRELDD 1909
Score = 32.7 bits (73), Expect = 3.2
Identities = 36/139 (25%), Positives = 69/139 (48%), Gaps = 16/139 (11%)
Query: 81 IKALKTELD-RTRIKVKELLRDRQADRHEVDDLMKQIAED-----KLVRKS-KEQDRLHA 133
+KA EL+ + K K + +A ++++ ++Q A++ KLVR++ K+ +
Sbjct: 1797 LKAKLQELEGAVKSKFKATISALEAKIGQLEEQLEQEAKERAAANKLVRRTEKKLKEIFM 1856
Query: 134 AVQSVRDELEDERKLRKRSESIHRKLARELSEMKSSFTSALKDLEQERTRRKLLEDLCDE 193
V+ R + ++ +++ + ++L R+L E + T A +RRKL +L D
Sbjct: 1857 QVEDERRHADQYKEQMEKANARMKQLKRQLEEAEEEATRA------NASRRKLQRELDD- 1909
Query: 194 FARGINE-YEQEVHTLKQK 211
A NE +EV TLK +
Sbjct: 1910 -ATEANEGLSREVSTLKNR 1927
>MYH3_HUMAN (P11055) Myosin heavy chain, fast skeletal muscle,
embryonic (Muscle embryonic myosin heavy chain) (SMHCE)
Length = 1940
Score = 53.5 bits (127), Expect = 2e-06
Identities = 51/235 (21%), Positives = 105/235 (43%), Gaps = 17/235 (7%)
Query: 64 LNRIWSLEEQHSSNISLIKALKTELDRTRIKVKELLRDRQADRHEVDDLMKQI--AEDKL 121
+ R LEE ++ + +++ K L + +Q + EV+DLM + A
Sbjct: 1381 IQRTEELEEAKKKLAQRLQDSEEQVEAVNAKCASLEKTKQRLQGEVEDLMVDVERANSLA 1440
Query: 122 VRKSKEQDRLHAAVQSVRDELEDERKLRKRSESIHRKLARELSEMKSSFTSALKDLEQER 181
K+Q + + + E+ + + S R L+ EL ++K+++ AL LE +
Sbjct: 1441 AALDKKQRNFDKVLAEWKTKCEESQAELEASLKESRSLSTELFKLKNAYEEALDQLETVK 1500
Query: 182 TRRKLLEDLCDEFARGINEYEQEVHTLKQKSEKDWVQRADHDRLVLHISESWLDER---- 237
K LE + I E + +H L++ ++ +++AD +L L +E+ L+
Sbjct: 1501 RENKNLEQEIADLTEQIAENGKTIHELEKSRKQIELEKAD-IQLALEEAEAALEHEEAKI 1559
Query: 238 MQMQLEAAQ------NGFMDKNSIVDKLSLEIETFIKAKQNSRSAE----NQVIR 282
+++QLE Q +K+ +++L + ++ Q++ AE N+ IR
Sbjct: 1560 LRIQLELTQVKSEIDRKIAEKDEEIEQLKRNYQRTVETMQSALDAEVRSRNEAIR 1614
Score = 51.2 bits (121), Expect = 9e-06
Identities = 84/404 (20%), Positives = 173/404 (42%), Gaps = 48/404 (11%)
Query: 71 EEQHSSNISLIKALKTELDRTRIKVKELLRDRQA--DRHE--VDDLMKQIAEDKLVRKSK 126
+E+H++ + +K L EL + +L R+++A + H+ +DDL Q EDK+ +K
Sbjct: 967 KEKHATE-NKVKNLTEELSGLDETIAKLTREKKALQEAHQQALDDL--QAEEDKVNSLNK 1023
Query: 127 EQDRLHAAVQSVRDELEDERKLRKRSESIHRKLARELSEMKSSFTSALKDLEQ--ERTRR 184
+ +L V+ + LE E+KLR E RKL +L + S D +Q ER ++
Sbjct: 1024 TKSKLEQQVEDLESSLEQEKKLRVDLERNKRKLEGDLKLAQESILDLENDKQQLDERLKK 1083
Query: 185 K------LLEDLCDEFARG-------------INEYEQEVHTLKQKSEKDWVQRADHDRL 225
K L + DE G I E E+E+ + K QR+D+ R
Sbjct: 1084 KDFEYCQLQSKVEDEQTLGLQFQKKIKELQARIEELEEEIEAERATRAKTEKQRSDYARE 1143
Query: 226 VLHISESWLDE-----RMQMQLEAAQNG-FMDKNSIVDKLSLEIETFIKAKQNSRSAENQ 279
+ +SE L+E Q++L + F+ +++ +L+ E + + +
Sbjct: 1144 LEELSER-LEEAGGVTSTQIELNKKREAEFLKLRRDLEEATLQHEAMVATLRKKHADSVA 1202
Query: 280 VIRDRRNSLESVPLNDAVSAPQAMGDDDDDDSVGSDSHCFELNKPSHMGAKVHKE-EILD 338
+ ++ ++L+ V Q + + + + D + S A + K L+
Sbjct: 1203 ELGEQIDNLQRV--------KQKLEKEKSEFKLEIDDLSSSMESVSKSKANLEKICRTLE 1254
Query: 339 KNLDETSKSNVKKKKSVPG-EGFKNHIPSNSNKKSQSVDAEEGLTTNIRLVEGTRISEEP 397
L E N + ++S+ K+ + + + + S+ ++ +E + + + + +++
Sbjct: 1255 DQLSEARGKNEEIQRSLSELTTQKSRLQTEAGELSRQLEEKESIVSQLSRSK-QAFTQQT 1313
Query: 398 EHFEISESGGFERKNNLSELHSTSKNHIIDNLIRGQLLASESGK 441
E + + KN L+ +S++ +L+R Q + GK
Sbjct: 1314 EELKRQLEEENKAKNALAHALQSSRHDC--DLLREQYEEEQEGK 1355
Score = 41.6 bits (96), Expect = 0.007
Identities = 59/273 (21%), Positives = 113/273 (40%), Gaps = 36/273 (13%)
Query: 61 LKVLNRIWSLEEQHSSNISLIKALKTELDRTRIKVKELLRDRQADRHEVDDLMKQI---- 116
+K L + E++ ++ + K EL ++ K KEL E +DL Q+
Sbjct: 837 IKPLLKSAETEKEMATMKEEFQKTKDELAKSEAKRKELEEKLVTLVQEKNDLQLQVQAES 896
Query: 117 -----AEDKLVRKSKEQDRLHAAVQSVRDELEDERKLRKRSESIHRKLARELSEMKS--- 168
AE++ + K + +L A ++ V + EDE ++ + RKL E SE+K
Sbjct: 897 ENLLDAEERCDQLIKAKFQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDID 956
Query: 169 --SFTSALKDLEQERTRRKL------LEDLCDEFARGINEYE--QEVHTL---KQKSEKD 215
T A + E+ T K+ L L + A+ E + QE H ++E+D
Sbjct: 957 DLELTLAKVEKEKHATENKVKNLTEELSGLDETIAKLTREKKALQEAHQQALDDLQAEED 1016
Query: 216 WVQRADHDRLVLHIS----ESWLDERMQMQLEAAQNGFMDKNSIVDKLSLEIETFIKAKQ 271
V + + L ES L++ +++++ +N K + L L E+ + +
Sbjct: 1017 KVNSLNKTKSKLEQQVEDLESSLEQEKKLRVDLERN----KRKLEGDLKLAQESILDLEN 1072
Query: 272 NSRSAENQVIRDRRNSLESVPLNDAVSAPQAMG 304
+ + + ++ ++ E L V Q +G
Sbjct: 1073 DKQQLDERL---KKKDFEYCQLQSKVEDEQTLG 1102
Score = 40.4 bits (93), Expect = 0.015
Identities = 57/241 (23%), Positives = 105/241 (42%), Gaps = 29/241 (12%)
Query: 59 ELLKVLNRIWSLEEQHSSNISLIKALKTELDRTRIKVKELLRDRQADRHEVDDLMKQIAE 118
ELL R+ L Q++S I K L+T+L + + +V++ RD R+ + K I +
Sbjct: 1706 ELLDSNERVQLLHTQNTSLIHTKKKLETDLMQLQSEVEDASRDA---RNAEEKAKKAITD 1762
Query: 119 DKLVRK--SKEQD----------RLHAAVQSVRDELEDERKLR--------KRSESIHRK 158
++ + KEQD L V+ ++ L++ +L ++ E+ R+
Sbjct: 1763 AAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLETRIRE 1822
Query: 159 LARELSEMKSSFTSALKDLEQERTRRKLLEDLCDEFARGINEYEQEVHTL--KQKSEKDW 216
L EL + T ++K L + R K L +E + + + V L K KS K
Sbjct: 1823 LEFELEGEQKKNTESVKGLRKYERRVKELTYQSEEDRKNVLRLQDLVDKLQVKVKSYKRQ 1882
Query: 217 VQRADHDRLVLHISESWLDERMQMQLEAAQNGFMDKNSIVDKLSLEIETFIKAKQNSRSA 276
+ AD ++ H+++ + Q +LE A+ S V+KL + F ++ +
Sbjct: 1883 AEEAD-EQANAHLTKF---RKAQHELEEAEERADIAESQVNKLRAKTRDFTSSRMVVHES 1938
Query: 277 E 277
E
Sbjct: 1939 E 1939
Score = 33.1 bits (74), Expect = 2.5
Identities = 39/172 (22%), Positives = 74/172 (42%), Gaps = 15/172 (8%)
Query: 53 SLKTSTELLKVLNRIWSLEEQHSSNISLIKALKTELDRTRIKVKELLRDRQADRHEVDDL 112
SLK S L L ++ + E+ + +K L++ + E + + HE++
Sbjct: 1471 SLKESRSLSTELFKLKNAYEEALDQLETVKRENKNLEQEIADLTEQIAENGKTIHELEKS 1530
Query: 113 MKQI----AEDKLVRKSKEQDRLHAAVQSVRDEL-------EDERKLRKRSESIH---RK 158
KQI A+ +L + E H + +R +L E +RK+ ++ E I R
Sbjct: 1531 RKQIELEKADIQLALEEAEAALEHEEAKILRIQLELTQVKSEIDRKIAEKDEEIEQLKRN 1590
Query: 159 LARELSEMKSSFTSALKDL-EQERTRRKLLEDLCDEFARGINEYEQEVHTLK 209
R + M+S+ + ++ E R ++K+ DL + + + Q TLK
Sbjct: 1591 YQRTVETMQSALDAEVRSRNEAIRLKKKMEGDLNEIEIQLSHANRQAAETLK 1642
>CING_XENLA (Q9PTD7) Cingulin
Length = 1360
Score = 53.5 bits (127), Expect = 2e-06
Identities = 84/348 (24%), Positives = 142/348 (40%), Gaps = 73/348 (20%)
Query: 49 EPHYSLKTSTELLKVLNRIWSLEEQHSSNISLIKALKTELDRTRIKVKELLRDRQADRHE 108
E +L+ T +L L ++ SL+ Q + + + K EL+R KV EL R +
Sbjct: 404 ESENTLRKKTSIL--LEKLPSLQVQPGEDTISLGSQKKELER---KVAELQR-------Q 451
Query: 109 VDDLMKQIAEDKLVRKSKEQDRLHAAVQSVRDELEDERKLRKRSESIHRKLARELSEMKS 168
+DD MKQ ++ Q R A +Q + ELE+ ++ R + ++ K ELS M
Sbjct: 452 LDDEMKQ-----RMKLETSQGRPKAGMQRLEIELEESKEECSRLKELYEKKKNELSAMSQ 506
Query: 169 SFTSALKDLEQERTRRKLLED--------LCDEFARG---------INEYEQ------EV 205
EQ T+ + +ED L A+G + E E+ EV
Sbjct: 507 ELMEVRMGKEQVETKLRTMEDKLMDSKEELSHLRAKGGTSPDKLALLKELEEVQDELDEV 566
Query: 206 HTLKQKSEKDWVQR---------------ADHDRLVLHISESWLDERMQMQLEAAQNGFM 250
++QK E+ Q+ A+HD+ + + E + ++ Q++ M
Sbjct: 567 LQIRQKQEELLRQKDRELTALKGALKDEVANHDKDLDRVREQYQNDMQQLRKN------M 620
Query: 251 DKNSIVDKLSLEIETFIKAKQNSRSAENQVIRDRRNSLESVPLNDAVSAPQAMGDDDDDD 310
D N D+LSLE E R NQV+R+ + LE +D +S + M + ++
Sbjct: 621 D-NVSQDQLSLESE---------RQKINQVVRNLQRELEE--SSDEISQWKEMFQKNKEE 668
Query: 311 SVGSDSHCFELNKPSHMGAKVHKEEILDKNLDETSKSNVKKKKSVPGE 358
+ ++ KE +L ++ + VKK PGE
Sbjct: 669 LRSTKQELLQMKLEKEESEDELKETRDRFSLLQSELAQVKKGSVDPGE 716
Score = 41.2 bits (95), Expect = 0.009
Identities = 35/143 (24%), Positives = 81/143 (56%), Gaps = 12/143 (8%)
Query: 53 SLKTSTELLKVLNRIWSLEEQH--SSNISLIKALKTEL-DRTRIKVKE---LLRDRQADR 106
SL+ + LK NR+ S+E Q S N+S ++A E+ +R +++ +E LL +
Sbjct: 1184 SLERQNKELK--NRLASMEGQQKPSVNVSHLEAKLQEIQERLQLEEREKATLLSTNRKLE 1241
Query: 107 HEVDDLMKQIAEDKLVRKSKEQDRLHAAVQSVRDELEDERKLRKRSESIHRKLAREL--- 163
++ +L Q+ ED+ ++ + ++D+L+ V++++ ++++ + +R E + +K RE+
Sbjct: 1242 RKLKELNIQL-EDERLQVNDQKDQLNLRVKALKRQVDEAEEEIERLEGLRKKAVREMEEQ 1300
Query: 164 SEMKSSFTSALKDLEQERTRRKL 186
E+ + +K +E+E R+ +
Sbjct: 1301 QEINEQLQTRVKVMEKESKRKPI 1323
Score = 37.0 bits (84), Expect = 0.17
Identities = 62/282 (21%), Positives = 116/282 (40%), Gaps = 44/282 (15%)
Query: 35 ATPNSSLDFKGRIGEPHYSLKTSTELLKVLNRIWSLEEQHSSNISLIKALKTELDRTRIK 94
+T L K E LK + + +L + ++ S + + +++ EL R + +
Sbjct: 671 STKQELLQMKLEKEESEDELKETRDRFSLLQSELAQVKKGSVDPGEVASVRKELQRVQDQ 730
Query: 95 VKELLRDRQ------ADRHEVDDLMKQIAEDKLVRKSKEQDRLHAAVQS----------- 137
+K+L D+Q R +K ++++ + +E RL +QS
Sbjct: 731 LKQLSVDKQKVEENLQQREREMSALKGTLKEEVSGRDRETVRLREQLQSEVMHVKKENEG 790
Query: 138 -------VRDELEDERKLRKRSESIHRKLARELSEMKSSFTSALKD--LEQERTRRKLLE 188
++D+L+ ++R E + RELS +K ALKD ++R KL E
Sbjct: 791 LAKESRRIQDQLKQVLLEKQRHEETVHQRERELSVLK----GALKDEVSGRDRETEKLRE 846
Query: 189 DLCDEFARGINEYEQEVHTLKQ-KSEKDWVQRADHDRLVLHISESWLDER------MQMQ 241
L + YE+ V K+ +SEK ++R V + E+ L E ++ +
Sbjct: 847 RLEQDALMTKRSYEELVKINKRLESEKTDLER------VRQVIENNLQESREENDDLRRK 900
Query: 242 LEAAQNGFMDKNSIVDKLSLEIETFIKAKQNSRSAENQVIRD 283
+ + + N+ D L E+ +K K N AE + + D
Sbjct: 901 ILGLEAQLKETNTFCDDLQ-RAESRLKDKINKLEAERKRMED 941
>MYH9_RAT (Q62812) Myosin heavy chain, nonmuscle type A (Cellular
myosin heavy chain, type A) (Nonmuscle myosin heavy
chain-A) (NMMHC-A)
Length = 1961
Score = 53.1 bits (126), Expect = 2e-06
Identities = 83/429 (19%), Positives = 176/429 (40%), Gaps = 64/429 (14%)
Query: 76 SNISLIKALKTELDRTRIKVKELLRDRQADRHEVDDLMKQIAEDKLVRKSKEQDRLHAAV 135
S + + L E +R ++ + L+ + +++ + +++ E+ K+ LHA V
Sbjct: 1308 SQLQDTQELLQEENRQKLSLSTKLKQMEDEKNSFREQLEEEEEEAKRNLEKQIATLHAQV 1367
Query: 136 QSVRDELEDERKLRKRSESIHRKLARELSEMKSSFTSALKDLEQ-ERTRRKLLEDLCDEF 194
++ ++ED + +E R+L ++L + + ++ E+T+ +L ++L D+
Sbjct: 1368 TDMKKKMEDGVGCLETAEEAKRRLQKDLEGLSQRLEEKVAAYDKLEKTKTRLQQEL-DDL 1426
Query: 195 ARGINEYEQEVHTLKQKSEKDWVQRADHDRLVLH---ISESWLDERMQMQLEA------- 244
++ Q V L++K +K D+L+ IS + +ER + + EA
Sbjct: 1427 LVDLDHQRQSVSNLEKKQKK-------FDQLLAEEKTISAKYAEERDRAEAEAREKETKA 1479
Query: 245 -----AQNGFMDKNSIVDKLS----LEIETFIKAK-----------QNSRSAENQV---- 280
A M++ + +++L+ E+E + +K +++R+ E QV
Sbjct: 1480 LSLARALEEAMEQKAELERLNKQFRTEMEDLMSSKDDVGKSVHELEKSNRALEQQVEEMK 1539
Query: 281 -----IRDRRNSLESVPLNDAVSAPQAMGDDDDDDSVGSDSHCFELNKPSHMGAKVHKEE 335
+ D + E L V+ QAM + D G D E K + + E
Sbjct: 1540 TQLEELEDELQATEDAKLRLEVNL-QAMKAQFERDLQGRDEQSEEKKKQLVRQVREMEAE 1598
Query: 336 ILDKNLDETSKSNVKKKKSVPGEGFKNHIPSNSNKKSQSVDAEEGLTTN----IRLVEGT 391
+ D+ + +KK + + + HI + + + +++ L +R V+ T
Sbjct: 1599 LEDERKQRSIAMAARKKLEMDLKDLEAHIDTANKNREEAIKQLRKLQAQMKDCMRDVDDT 1658
Query: 392 RISEEPEHFEISESGGFERKNNLSELHSTSKNHIIDNLIRGQLLASESGKNNKHAEHNNY 451
R S E EI + K N +L S I ++ +L A+E K E +
Sbjct: 1659 RASRE----EILA----QAKENEKKLKSMEAEMI---QLQEELAAAERAKRQAQQERDEL 1707
Query: 452 GEASCSNAG 460
+ +++G
Sbjct: 1708 ADEIANSSG 1716
Score = 42.4 bits (98), Expect = 0.004
Identities = 57/251 (22%), Positives = 99/251 (38%), Gaps = 39/251 (15%)
Query: 42 DFKGRIGEPHYSLK-TSTELLKVLNRIWSLEEQHSSNISLIKALKTELDRTRIKVKELLR 100
D + R+ E + E K+ I LEEQ S + L+ E T K+K+L
Sbjct: 919 DLEARVEEEEERCQYLQAEKKKMQQNIQELEEQLEEEESARQKLQLEKVTTEAKLKKLEE 978
Query: 101 DRQADRHEVDDLMKQIAEDKLVRKSKEQDRLHAAVQSVRDELEDERKLRKRSESIHRKLA 160
D+ I ED+ + +KE+ L V +L +E + K + K
Sbjct: 979 DQI------------IMEDQNCKLAKEKKLLEDRVAEFTTDLMEEEEKSKSLAKLKNKHE 1026
Query: 161 RELSEMKSSFTSALKDLEQ-ERTRRKLLEDLCDEFARGINEYEQEVHTLKQKSEKDWVQR 219
+++++ K ++ E+TRRKL D D + I E + ++ LK + K
Sbjct: 1027 AMITDLEERLRREEKQRQELEKTRRKLEGDSTD-LSDQIAELQAQIAELKMQLAKK---- 1081
Query: 220 ADHDRLVLHISESWLDERMQMQLEAAQNGFMDKNSIVDKLSLEIETFIKAKQ----NSRS 275
+E +Q L + KN + K+ E+ET I Q + R+
Sbjct: 1082 ---------------EEELQAALARVEEEAAQKNMALKKIR-ELETQISELQEDLESERA 1125
Query: 276 AENQVIRDRRN 286
N+ + +R+
Sbjct: 1126 CRNKAEKQKRD 1136
Score = 40.4 bits (93), Expect = 0.015
Identities = 46/218 (21%), Positives = 92/218 (42%), Gaps = 10/218 (4%)
Query: 81 IKALKTELDRTRIKVKELLRDRQADRHEVDDLMKQIAEDKLVRKSKEQD---RLHAAVQS 137
++ALKTEL+ T R EV L K + ++ +++ Q+ + AV+
Sbjct: 1141 LEALKTELEDTLDSTAAQQELRSKREQEVSILKKTLEDEAKTHEAQIQEMRQKHSQAVEE 1200
Query: 138 VRDELEDERKLRKRSESIHRKLARELSEMKSSFTSALKDLEQERTRRKLLEDLCDEFARG 197
+ ++LE ++++ E + L E E+ + + L+ +RK +E E
Sbjct: 1201 LAEQLEQTKRVKATLEKAKQTLENERGELANEVKALLQGKGDSEHKRKKVEAQLQELQVK 1260
Query: 198 INEYEQEVHTLKQKSEKDWVQRADHDRLVLHISESWLDE------RMQMQLEAAQNGFMD 251
+E E+ L K K V+ D +L+ S+S + ++ QL+ Q +
Sbjct: 1261 FSEGERVRTELADKVSKLQVE-LDSVTGLLNQSDSKSSKLTKDFSALESQLQDTQELLQE 1319
Query: 252 KNSIVDKLSLEIETFIKAKQNSRSAENQVIRDRRNSLE 289
+N LS +++ K + R + + + +LE
Sbjct: 1320 ENRQKLSLSTKLKQMEDEKNSFREQLEEEEEEAKRNLE 1357
Score = 33.5 bits (75), Expect = 1.9
Identities = 29/133 (21%), Positives = 60/133 (44%), Gaps = 3/133 (2%)
Query: 82 KALKTELDRTRIKVKELLRDRQADRH-EVDDLMKQIAEDKLVRK--SKEQDRLHAAVQSV 138
K LK +L VK + A ++ L +Q+ + R+ SK+ R ++ V
Sbjct: 1789 KELKAKLQEMESAVKSKYKASIAALEAKIAQLEEQLDNETKERQAASKQVRRAEKKLKDV 1848
Query: 139 RDELEDERKLRKRSESIHRKLARELSEMKSSFTSALKDLEQERTRRKLLEDLCDEFARGI 198
++EDER+ ++ + K + L ++K A ++ ++ R+ L+ ++
Sbjct: 1849 LLQVEDERRNAEQFKDQADKASTRLKQLKRQLEEAEEEAQRANASRRKLQRELEDATETA 1908
Query: 199 NEYEQEVHTLKQK 211
+ +EV +LK K
Sbjct: 1909 DAMNREVSSLKNK 1921
Score = 33.5 bits (75), Expect = 1.9
Identities = 51/250 (20%), Positives = 104/250 (41%), Gaps = 25/250 (10%)
Query: 73 QHSSNISLIKALKTELDRTRIKVKELLRDRQADRHEVDDLMKQIAED--KLVRKSKEQDR 130
Q N +K+++ E+ + + ++ R ++ + E D+L +IA K +E+ R
Sbjct: 1668 QAKENEKKLKSMEAEMIQLQEELAAAERAKRQAQQERDELADEIANSSGKGALALEEKRR 1727
Query: 131 LHAAVQSVRDELEDE-----------RKLRKRSESIHRKLARELSEMKSSFTSALKDLEQ 179
L A + + +ELE+E +K + + I+ L E S + + +A + LE+
Sbjct: 1728 LEALIALLEEELEEEQGNTELINDRLKKANLQIDQINTDLNLERSHAQKN-ENARQQLER 1786
Query: 180 ERTRRK-----LLEDLCDEFARGINEYEQEVHTLKQKSEKDWVQRADHDRLVLHISESWL 234
+ K + + ++ I E ++ L+++ + + +R + V +
Sbjct: 1787 QNKELKAKLQEMESAVKSKYKASIAALEAKIAQLEEQLDNETKERQAASKQVRRAEKKLK 1846
Query: 235 DERMQMQLEAAQ-NGFMDKNSIVDKLSLEIETFIKAKQNSRSAENQVIRDRRNSLESVPL 293
D +Q++ E F D+ DK S ++ +K + E Q R L+ L
Sbjct: 1847 DVLLQVEDERRNAEQFKDQ---ADKASTRLKQ-LKRQLEEAEEEAQRANASRRKLQR-EL 1901
Query: 294 NDAVSAPQAM 303
DA AM
Sbjct: 1902 EDATETADAM 1911
Score = 32.7 bits (73), Expect = 3.2
Identities = 25/126 (19%), Positives = 56/126 (43%), Gaps = 14/126 (11%)
Query: 42 DFKGRIGEPHYSLKTS--TELLKVLNRIWSLEEQHSSNISLIKALKTELDRTRIKVKELL 99
+ K ++ E ++K+ + + +I LEEQ + +A ++ R K+K++L
Sbjct: 1790 ELKAKLQEMESAVKSKYKASIAALEAKIAQLEEQLDNETKERQAASKQVRRAEKKLKDVL 1849
Query: 100 RDRQADRHEVDDLMKQIAEDKLVRKSKEQDRLHAAVQSVRDELEDERKLRKRSESIHRKL 159
+ +R + Q D+ ++ ++ +LE+ + +R+ + RKL
Sbjct: 1850 LQVEDERRNAEQFKDQ------------ADKASTRLKQLKRQLEEAEEEAQRANASRRKL 1897
Query: 160 ARELSE 165
REL +
Sbjct: 1898 QRELED 1903
>TRHY_RABIT (P37709) Trichohyalin
Length = 1407
Score = 52.8 bits (125), Expect = 3e-06
Identities = 45/197 (22%), Positives = 99/197 (49%), Gaps = 14/197 (7%)
Query: 59 ELLKVLNRIWSLEEQHSSNISLIKALKTELDRTRIKVKELLRDRQADRHEVDDLMKQIAE 118
+L + +R + EEQ + + E +R + ++LL++R+ +R + +++ E
Sbjct: 765 QLRRERDRKFREEEQLLQEREEERLRRQERERKLREEEQLLQEREEERLRRQERERKLRE 824
Query: 119 DKLVRKSKEQDRLHAAVQSVRDELEDERKLRKRSESIHRKLARELSEMKSSFTSALKDLE 178
++ + + +E++RL + R E+E+ LR+ + + ++ AR+L E + ++L
Sbjct: 825 EEQLLQEREEERLRRQERE-RKLREEEQLLRQEEQELRQERARKLREEEQLLRQEEQELR 883
Query: 179 QERTR---------RKLLEDLCDEFARGINEYEQEVHTLKQKSEKDWVQRADHDRLVLHI 229
QER R R+ ++L E R + E EQ L Q+SE++ ++R + +R +
Sbjct: 884 QERDRKLREEEQLLRQEEQELRQERDRKLREEEQ----LLQESEEERLRRQERERKLREE 939
Query: 230 SESWLDERMQMQLEAAQ 246
+ E +++ E A+
Sbjct: 940 EQLLRREEQELRRERAR 956
Score = 51.6 bits (122), Expect = 7e-06
Identities = 44/188 (23%), Positives = 90/188 (47%), Gaps = 6/188 (3%)
Query: 59 ELLKVLNRIWSLEEQHSSNISLIKALKTELDRTRIKVKELLRDRQADRHEVDDLMKQIAE 118
E L+ R L E+ + L+ E DR + ++LL++ + +R + +++ E
Sbjct: 1113 ERLRRQERARKLREEEQLLRREEQLLRQERDRKFREEEQLLQESEEERLRRQERERKLRE 1172
Query: 119 DKLVRKSKEQDRLHAAVQSVRDELEDERKLRKRSESIHRKLARELSEMKSSFTSALKDLE 178
++ + + +E++RL + R E+E+ LR+ + + ++ AR+L E + ++L
Sbjct: 1173 EEQLLQEREEERLRRQ-ERARKLREEEQLLRQEEQELRQERARKLREEEQLLRQEEQELR 1231
Query: 179 QERTRR-----KLLEDLCDEFARGINEYEQEVHTLKQKSEKDWVQRADHDRLVLHISESW 233
QER R+ +LL E R + +E L Q+ E++ ++R + R + E
Sbjct: 1232 QERDRKFREEEQLLRREEQELRRERDRKFREEEQLLQEREEERLRRQERARKLREEEEQL 1291
Query: 234 LDERMQMQ 241
L E + Q
Sbjct: 1292 LFEEQEEQ 1299
Score = 47.0 bits (110), Expect = 2e-04
Identities = 53/223 (23%), Positives = 99/223 (43%), Gaps = 15/223 (6%)
Query: 71 EEQHSSNISLIKALKTELDRTRIKVKELLRDRQADRHEVDDLMKQIAEDKLVRKSKEQDR 130
EE+ + L+ E R + +EL ++R+ E + L+++ E++L+R+ E+DR
Sbjct: 685 EEERLRRQERARKLREEEQLLRQEEQELRQERERKLREEEQLLRR--EEQLLRQ--ERDR 740
Query: 131 LHAAVQSVRDELEDERKLRKRSESIHRKLARELSEMKSSFTSALKDLEQERTRRKLLEDL 190
+ + E E+ER R+ E ++L RE L++ E+ER RR+ E
Sbjct: 741 KLREEEQLLQESEEERLRRQERE---QQLRRERDRKFREEEQLLQEREEERLRRQERERK 797
Query: 191 CDEFARGINEYEQE-----VHTLKQKSEKDWVQRADHDRLVLHISESWLDERMQMQLEAA 245
E + + E E+E K + E+ +Q + +RL E L E Q+ +
Sbjct: 798 LREEEQLLQEREEERLRRQERERKLREEEQLLQEREEERLRRQERERKLREEEQLLRQEE 857
Query: 246 QNGFMDKNSIVDKLSLEIETFIKAKQNSRSAENQVIRDRRNSL 288
Q ++ KL E + + +Q R ++ +R+ L
Sbjct: 858 QELRQER---ARKLREEEQLLRQEEQELRQERDRKLREEEQLL 897
Score = 47.0 bits (110), Expect = 2e-04
Identities = 42/160 (26%), Positives = 85/160 (52%), Gaps = 13/160 (8%)
Query: 84 LKTELDRTRIKVKELLRDRQADRHEVDDLMKQIAEDKLVRKSKEQDRLHAAVQSVRDELE 143
L+ E +R + ++LL++R+ +R + +++ E++ + + +EQ+ + +R E
Sbjct: 666 LRQERERKLREEEQLLQEREEERLRRQERARKLREEEQLLRQEEQELRQERERKLR---E 722
Query: 144 DERKLRKRSESIHRKLARELSEMKSSFTSALKDLEQERTRRKLLE-DLCDEFARGINEYE 202
+E+ LR+ + + ++ R+L E + L++ E+ER RR+ E L E R E E
Sbjct: 723 EEQLLRREEQLLRQERDRKLREEE----QLLQESEEERLRRQEREQQLRRERDRKFREEE 778
Query: 203 QEVHTLKQKSEKDWVQRADHDRLVLHISESWLDERMQMQL 242
Q L Q+ E++ ++R + +R L E L ER + +L
Sbjct: 779 Q----LLQEREEERLRRQERER-KLREEEQLLQEREEERL 813
Score = 44.3 bits (103), Expect = 0.001
Identities = 50/231 (21%), Positives = 99/231 (42%), Gaps = 28/231 (12%)
Query: 71 EEQHSSNISLIKALKTELDRTRIKVKELLRDRQADRHEVDDLMKQIAEDKLVRKSKEQ-- 128
EEQ + L+ E DR + ++LL++R+ +R + +++ E++ + + +EQ
Sbjct: 1079 EEQQRRRQEREQQLRRERDRKFREEEQLLQEREEERLRRQERARKLREEEQLLRREEQLL 1138
Query: 129 ----DRLHAAVQSVRDELEDERKLRKRSESIHRKLARELSEMKSSFTSALKDLEQERTRR 184
DR + + E E+ER R+ E RKL E L++ E+ER RR
Sbjct: 1139 RQERDRKFREEEQLLQESEEERLRRQERE---RKLREE--------EQLLQEREEERLRR 1187
Query: 185 KLLEDLCDEFARGINEYEQEVHTLKQKSEKDWVQRADHDRLVLHISESWL----DERMQM 240
+ E AR + E EQ + +Q+ ++ ++ + +L E L D + +
Sbjct: 1188 Q-------ERARKLREEEQLLRQEEQELRQERARKLREEEQLLRQEEQELRQERDRKFRE 1240
Query: 241 QLEAAQNGFMDKNSIVDKLSLEIETFIKAKQNSRSAENQVIRDRRNSLESV 291
+ + + + D+ E E ++ ++ R + R R E +
Sbjct: 1241 EEQLLRREEQELRRERDRKFREEEQLLQEREEERLRRQERARKLREEEEQL 1291
Score = 43.9 bits (102), Expect = 0.001
Identities = 44/200 (22%), Positives = 93/200 (46%), Gaps = 25/200 (12%)
Query: 84 LKTELDRTRIKVKELLRDRQADRHEVDDLMKQIAEDKLVRKSKEQDRLHAAVQSVRDELE 143
L+ E DR + ++LL++ + +R + +++ E++ + + +EQ+ + +R E
Sbjct: 904 LRQERDRKLREEEQLLQESEEERLRRQERERKLREEEQLLRREEQELRRERARKLR---E 960
Query: 144 DERKLRKRSESIHRKLARELSEMKSSFTSALKDLEQERTRRKLLEDLCDEFARGINEYEQ 203
+E+ L++R E R+ R A K E+E+ R+ ++L E R E EQ
Sbjct: 961 EEQLLQEREEERLRRQER-----------ARKLREEEQLLRREEQELRQERDRKFREEEQ 1009
Query: 204 EVHTLKQKSEKDWVQRADHDRLVLHISESWLDERMQMQLEAAQNGFMDKNSIVDKLSLEI 263
L Q+ E++ ++R + DR + +E Q++ + + F + +L +I
Sbjct: 1010 ----LLQEREEERLRRQERDR-------KFREEERQLRRQELEEQFRQERDRKFRLEEQI 1058
Query: 264 ETFIKAKQNSRSAENQVIRD 283
+ KQ R ++ R+
Sbjct: 1059 RQEKEEKQLRRQERDRKFRE 1078
Score = 43.5 bits (101), Expect = 0.002
Identities = 34/154 (22%), Positives = 78/154 (50%), Gaps = 14/154 (9%)
Query: 89 DRTRIKVKELLRDRQADRHEVDDLMKQIAEDKLVRKSKEQDRLHAAVQSVRDELEDERKL 148
DR + ++LL++R+ +R + +++ E++ + + +EQ+ + +R E+E+ L
Sbjct: 603 DRKLREEEQLLQEREEERLRRQERERKLREEEQLLRQEEQELRQERERKLR---EEEQLL 659
Query: 149 RKRSESIHRKLARELSEMKSSFTSALKDLEQERTRRKLLEDLCDEFARGINEYEQEVHTL 208
R+ + + ++ R+L E + L++ E+ER RR+ E AR + E EQ +
Sbjct: 660 RREEQELRQERERKLREEE----QLLQEREEERLRRQ-------ERARKLREEEQLLRQE 708
Query: 209 KQKSEKDWVQRADHDRLVLHISESWLDERMQMQL 242
+Q+ ++ ++ + +L E L + +L
Sbjct: 709 EQELRQERERKLREEEQLLRREEQLLRQERDRKL 742
Score = 42.7 bits (99), Expect = 0.003
Identities = 51/217 (23%), Positives = 100/217 (45%), Gaps = 30/217 (13%)
Query: 82 KALKTELDRTRIKVKELLRDRQADRHEVDDLMKQIAEDKLVRKSKEQDRLHAAVQSVRDE 141
K + E R +++E R + + +++ ++Q E+K +R+ +E+DR R+E
Sbjct: 1027 KFREEERQLRRQELEEQFRQERDRKFRLEEQIRQEKEEKQLRR-QERDR------KFREE 1079
Query: 142 LEDERKLRKRSESIHRKLARELSEMKSSFTSALKDLEQERTRRKLLEDLCDEFARGINEY 201
E +R+ ++R + + R+ R+ E + L++ E+ER RR+ E AR + E
Sbjct: 1080 -EQQRRRQEREQQLRRERDRKFREEE----QLLQEREEERLRRQ-------ERARKLREE 1127
Query: 202 EQ----EVHTLKQ------KSEKDWVQRADHDRLVLHISESWLDERMQMQLEAAQNGFMD 251
EQ E L+Q + E+ +Q ++ +RL E L E Q+ L+ + +
Sbjct: 1128 EQLLRREEQLLRQERDRKFREEEQLLQESEEERLRRQERERKLREEEQL-LQEREEERLR 1186
Query: 252 KNSIVDKLSLEIETFIKAKQNSRSAENQVIRDRRNSL 288
+ KL E + + +Q R + +R+ L
Sbjct: 1187 RQERARKLREEEQLLRQEEQELRQERARKLREEEQLL 1223
Score = 39.3 bits (90), Expect = 0.034
Identities = 37/157 (23%), Positives = 72/157 (45%), Gaps = 8/157 (5%)
Query: 71 EEQHSSNISLIKALKTELDRTRIKVKELLRDRQADRHEVDDLMKQIAEDKLVRKSKEQDR 130
EE+ + L+ E R + +EL R+R E + L+++ E++L R+ + +
Sbjct: 923 EEERLRRQERERKLREEEQLLRREEQELRRERARKLREEEQLLQEREEERL-RRQERARK 981
Query: 131 LHAAVQSVRDELEDERKLRKRSESIHRKLARELSE---MKSSFTSALKDLEQERTRRKLL 187
L Q +R E ++ R+ R R +L +E E + ++ E++ R++L
Sbjct: 982 LREEEQLLRREEQELRQERDRKFREEEQLLQEREEERLRRQERDRKFREEERQLRRQELE 1041
Query: 188 EDLCDEFARGINEYEQEVHTLKQKSEKDWVQRADHDR 224
E E R EQ ++Q+ E+ ++R + DR
Sbjct: 1042 EQFRQERDRKFRLEEQ----IRQEKEEKQLRRQERDR 1074
Score = 38.9 bits (89), Expect = 0.045
Identities = 32/137 (23%), Positives = 67/137 (48%), Gaps = 6/137 (4%)
Query: 82 KALKTELDRTRIKVKELLRDRQADRHEVDDLMKQIAEDKLVRKSKEQDRLHAAVQSVRDE 141
+ + E R + +EL R+R E + L+++ E++L R+ + + +L + + E
Sbjct: 1236 RKFREEEQLLRREEQELRRERDRKFREEEQLLQEREEERLRRQERAR-KLREEEEQLLFE 1294
Query: 142 LEDERKLRKRSESIHR---KLARELSEMKSSFTSALKDLEQERTRRKLLEDLCDEFARGI 198
++E++LR+ + +R + ARE E L+ E++R RR+ +E R
Sbjct: 1295 EQEEQRLRQERDRRYRAEEQFARE--EKSRRLERELRQEEEQRRRRERERKFREEQLRRQ 1352
Query: 199 NEYEQEVHTLKQKSEKD 215
E EQ L+++ ++
Sbjct: 1353 QEEEQRRRQLRERQFRE 1369
Score = 36.6 bits (83), Expect = 0.22
Identities = 52/232 (22%), Positives = 104/232 (44%), Gaps = 29/232 (12%)
Query: 68 WSLEEQHSSNISLIKALKTELDRTRIKVKELLRDRQADRHEVDDLMKQIAEDKLVRKSKE 127
W L+E+ + A + ++ R + +EL R+++ E + E+KL R+ E
Sbjct: 524 WQLQEEAQRRRHTLYAKPGQQEQLR-EEEELQREKRRQERE----REYREEEKLQREEDE 578
Query: 128 QDRLHAAVQSVRD--ELEDERKLRKRSESIHRKLARELSEMKSSFTSALKDLEQERTRR- 184
+ R + R+ EL E +LR R +L +E E + L+ E+ER R
Sbjct: 579 KRRRQERERQYRELEELRQEEQLRDRKLREEEQLLQEREEER------LRRQERERKLRE 632
Query: 185 --KLL----EDLCDEFARGINEYEQEVHTLKQKSEKDWVQRADHDRLVLHISESWLDERM 238
+LL ++L E R + E EQ + +Q+ ++ ++ + +L E +ER+
Sbjct: 633 EEQLLRQEEQELRQERERKLREEEQLLRREEQELRQERERKLREEEQLLQERE---EERL 689
Query: 239 QMQLEAAQNGFMDKNSIV----DKLSLEIETFIKAKQNSRSAENQVIRDRRN 286
+ Q A + ++ ++ +L E E ++ ++ E Q++R R+
Sbjct: 690 RRQERARK--LREEEQLLRQEEQELRQERERKLREEEQLLRREEQLLRQERD 739
Score = 35.4 bits (80), Expect = 0.49
Identities = 45/176 (25%), Positives = 84/176 (47%), Gaps = 21/176 (11%)
Query: 71 EEQHSSNISLIKALKTELDRTRIKVKELLRDRQADRHEVDDLMKQIAEDKLVRKSKEQDR 130
+E+ + L+ E R + +EL ++R E + L+++ E++ +R+ E+DR
Sbjct: 1203 QEEQELRQERARKLREEEQLLRQEEQELRQERDRKFREEEQLLRR--EEQELRR--ERDR 1258
Query: 131 LHAAVQSVRDELEDERKLRKRSESIHRKLARELSEMKSSFTSALKDLEQERTRRKLLEDL 190
+ + E E+ER LR++ + RKL RE E + L QER RR E
Sbjct: 1259 KFREEEQLLQEREEER-LRRQERA--RKL-REEEEQLLFEEQEEQRLRQERDRRYRAE-- 1312
Query: 191 CDEFARGINEYEQEVHTLKQKSEKDWVQRADHDRLVLHISESWLDERMQMQLEAAQ 246
++FAR E++ L+++ ++ QR +R + +E+++ Q E Q
Sbjct: 1313 -EQFAR-----EEKSRRLERELRQEEEQRRRRER-----ERKFREEQLRRQQEEEQ 1357
Score = 34.7 bits (78), Expect = 0.84
Identities = 33/136 (24%), Positives = 65/136 (47%), Gaps = 24/136 (17%)
Query: 84 LKTELDRTRIKVKELLRDRQADR-----------HEVDDLMKQIAEDKLVRKSKEQDRLH 132
L+ E DR + ++LL++R+ +R E + L+ + E++ +R+ +++ R
Sbjct: 1252 LRRERDRKFREEEQLLQEREEERLRRQERARKLREEEEQLLFEEQEEQRLRQERDR-RYR 1310
Query: 133 AAVQSVRDELED--ERKLRKRSESIHRK----------LARELSEMKSSFTSALKDLEQE 180
A Q R+E ER+LR+ E R+ L R+ E + + ++
Sbjct: 1311 AEEQFAREEKSRRLERELRQEEEQRRRRERERKFREEQLRRQQEEEQRRRQLRERQFRED 1370
Query: 181 RTRRKLLEDLCDEFAR 196
++RR++LE +FAR
Sbjct: 1371 QSRRQVLEPGTRQFAR 1386
Score = 32.7 bits (73), Expect = 3.2
Identities = 32/129 (24%), Positives = 59/129 (44%), Gaps = 30/129 (23%)
Query: 99 LRDRQAD------RHEVDDLMKQIAEDKLVRKSKEQDRLHAAVQS-------VRDELEDE 145
LRDRQ + R + + +++AE++ RK +E+ H + Q R ELE+
Sbjct: 123 LRDRQFEDEPERRRWQKQEQERELAEEEEQRKKRERFEQHYSRQYRDKEQRLQRQELEER 182
Query: 146 RKLRKRSESIHRKLARELSEMKSSFTSALKDLEQERTRRKLLEDLCDEFARGINEYEQEV 205
R E + R+ R+ E +E+E+ RR+ ++L R + E EQ+
Sbjct: 183 RA---EEEQLRRRKGRDAEEF----------IEEEQLRRREQQEL----KRELREEEQQR 225
Query: 206 HTLKQKSEK 214
+++ E+
Sbjct: 226 RERREQHER 234
Score = 32.7 bits (73), Expect = 3.2
Identities = 40/195 (20%), Positives = 84/195 (42%), Gaps = 17/195 (8%)
Query: 85 KTELDRTRIKVKELLRDRQADRHEVDDLMKQIAEDKLVRKSKEQDRLHAAVQSVRDELED 144
+ EL+ R + ++L R + D E I E++L R+ +++ + R+ E+
Sbjct: 176 RQELEERRAEEEQLRRRKGRDAEEF------IEEEQLRRREQQELK--------RELREE 221
Query: 145 ERKLRKRSESIHRKLARELSEMKSSFTSALKDLEQERTRRKLLEDLCDEFARGINEYEQE 204
E++ R+R E R L E ++ + EQ++ RR+L E E + + + E+
Sbjct: 222 EQQRRERREQHERALQEEEEQLLRQRRWREEPREQQQLRRELEE--IREREQRLEQEERR 279
Query: 205 VHTLKQKSEKDWVQRADHDRLVLHISESWLDERMQMQLEAAQNGFMDKNSIVDKLSLEIE 264
L+++ + +R + +L + E E+ Q E + + +L E+E
Sbjct: 280 EQQLRREQRLEQEERRE-QQLRRELEEIREREQRLEQEERREQRLEQEERREQQLKRELE 338
Query: 265 TFIKAKQNSRSAENQ 279
+ +Q E +
Sbjct: 339 EIREREQRLEQEERR 353
Score = 31.6 bits (70), Expect = 7.1
Identities = 26/114 (22%), Positives = 52/114 (44%), Gaps = 6/114 (5%)
Query: 174 LKDLEQERTRRKLLED--LCDEFARGINEYEQEVHTLKQKSEKDWVQRADHDRLVLHISE 231
L++ QE RR L D DE R + +++ L ++ E QR +R H S
Sbjct: 110 LQNRRQEDQRRFELRDRQFEDEPERRRWQKQEQERELAEEEE----QRKKRERFEQHYSR 165
Query: 232 SWLDERMQMQLEAAQNGFMDKNSIVDKLSLEIETFIKAKQNSRSAENQVIRDRR 285
+ D+ ++Q + + ++ + + + E FI+ +Q R + ++ R+ R
Sbjct: 166 QYRDKEQRLQRQELEERRAEEEQLRRRKGRDAEEFIEEEQLRRREQQELKRELR 219
Score = 31.6 bits (70), Expect = 7.1
Identities = 41/214 (19%), Positives = 88/214 (40%), Gaps = 22/214 (10%)
Query: 49 EPHYSLKTSTELLKVLNRIWSLEEQHSSNISLIKALKTELDRTRIKVKELLRDRQADRHE 108
EP + EL ++ R LE++ L + + E + R ++L R+ + R
Sbjct: 252 EPREQQQLRRELEEIREREQRLEQEERREQQLRREQRLEQEERR--EQQLRRELEEIRER 309
Query: 109 VDDL-MKQIAEDKLVRKSKEQDRLHAAVQSVRDE---LEDERK------------LRKRS 152
L ++ E +L ++ + + +L ++ +R+ LE E + R+R
Sbjct: 310 EQRLEQEERREQRLEQEERREQQLKRELEEIREREQRLEQEERREQLLAEEVREQARERG 369
Query: 153 ESIHRKLARELSEMKSSFTSALKDLEQERTRRKLLEDLCDEFARGINEYEQEVHTLKQKS 212
ES+ R+ R+L + S + + + + L + D+ R E E+E+ + +
Sbjct: 370 ESLTRRWQRQLESEAGARQSKVYSRPRRQEEQSLRQ---DQERRQRQERERELEE-QARR 425
Query: 213 EKDWVQRADHDRLVLHISESWLDERMQMQLEAAQ 246
++ W + +R +S Q++ E Q
Sbjct: 426 QQQWQAEEESERRRQRLSARPSLRERQLRAEERQ 459
>MYSP_BOOMI (Q86RN8) Paramyosin
Length = 873
Score = 52.8 bits (125), Expect = 3e-06
Identities = 64/236 (27%), Positives = 107/236 (45%), Gaps = 12/236 (5%)
Query: 59 ELLKVLNRIWSLEEQHSSNISLIKALKTELDRTRIKVKELLRDRQADRHEVDDLMKQIAE 118
+L +L R +LE+Q S S ++ L +L++ + L + R A +++ +K E
Sbjct: 325 QLEALLTRCSNLEKQKSRLQSEVEVLIMDLEKATAHAQNLEK-RVAQLEKLNIDLKSKVE 383
Query: 119 DKLVRKSKEQDRLH---AAVQSVRDELEDERKLRKRSESIHRKLARELSEMKSSFTSALK 175
+ + + Q L A +Q ++ E E R+ R + ++KL +LSE KS A++
Sbjct: 384 ELTILLEQSQRELRQKVAEIQKLQHEYEKMREQRDALQRENKKLVDDLSEAKSQLADAIR 443
Query: 176 DLEQERTRRKLLEDLCDEFARGINEYE----QEVHTLKQKSEKDWVQRADHDRLVLHISE 231
L + K LE+ DE A E E QE ++ + + R +++R L I E
Sbjct: 444 RLHEYELEIKRLENERDELAAAYKEAETLRKQEEAKCQRLTAELAQVRHEYERR-LQIKE 502
Query: 232 SWLDE-RMQMQLEAAQNGFMDKNSIVDKLSLEIETFIKAKQNSRSAENQVIRDRRN 286
++ R Q QLE Q M KL EI IK K ++ E ++ D N
Sbjct: 503 EEIEALRKQYQLEVEQLN-MRLAEAEAKLKTEIAR-IKKKYQAQITELEMSLDAAN 556
Score = 39.7 bits (91), Expect = 0.026
Identities = 56/269 (20%), Positives = 111/269 (40%), Gaps = 42/269 (15%)
Query: 55 KTSTELLKVLNRIWSLEEQHSSNISLIKALKTELDRTRIKVKELLRDRQADRHEVDDLMK 114
+T TE+ R L +++ + + LK LD +L + R ++D
Sbjct: 190 RTVTEVTAQRTR---LSAENAEYLKEVHELKVSLDNVNHLKSQLATQLEDTRRRLED--- 243
Query: 115 QIAEDKLVRKSKEQDRLHAAVQSVRDELEDERKLRKRSESIHRKLARELSEMKSSFTSAL 174
E K L ++S++ +LE+E + R E K + + K+ + + +
Sbjct: 244 --EERKRASLESSMHTLEVEIESLKVQLEEESEARLEVERQLVKANADAAAYKTKYETEV 301
Query: 175 KDLEQERTRRKLLEDLCDEFARGINEYEQEVHTL--------KQKS-------------E 213
+ E +E+L + A+ I+EYE+++ L KQKS E
Sbjct: 302 QAHADE------VEELRRKMAQKISEYEEQLEALLTRCSNLEKQKSRLQSEVEVLIMDLE 355
Query: 214 KDWVQRADHDRLVLHISESWLD-----ERMQMQLEAAQNGFMDKNSIVDKLSLEIETFIK 268
K + ++ V + + +D E + + LE +Q K + + KL E E ++
Sbjct: 356 KATAHAQNLEKRVAQLEKLNIDLKSKVEELTILLEQSQRELRQKVAEIQKLQHEYEK-MR 414
Query: 269 AKQNSRSAENQVIRDRRNSLESVPLNDAV 297
++++ EN+ + D + +S L DA+
Sbjct: 415 EQRDALQRENKKLVDDLSEAKS-QLADAI 442
Score = 37.7 bits (86), Expect = 0.100
Identities = 42/199 (21%), Positives = 84/199 (42%), Gaps = 31/199 (15%)
Query: 82 KALKTELDRTRIKVKELLRDRQADRHEVDDLMKQIAEDKLVRKSKEQDRLHAAVQSVRDE 141
K + E IKV+ + + + + + ++++ + L + +L A ++ V E
Sbjct: 689 KDILVEEQERYIKVESIKKSLEVEVRNLQVRLEEVEANALAGGKRVIAKLEARIRDVEIE 748
Query: 142 LEDERKLRKRSESIHRKLARELSEMKSSFTSALKDLEQERTRRKLLEDLCDEFARGINEY 201
LE+E+K ++ I RK E+ L E++ +L D ++ + Y
Sbjct: 749 LEEEKKRHAETQKILRKKDHRAKEL-------LLQTEEDHKTITMLNDAVEKLNEKVKVY 801
Query: 202 EQEVHTLKQKSEKDWVQRADHDRLVLHISESWLDERMQMQLEAAQNGFMDKNSIVDKLSL 261
+ +Q +E++ + + + R+ R Q +LEAA++ +S LSL
Sbjct: 802 K------RQLNEQEGLSQQNLTRV----------RRFQRELEAAED---RADSAESNLSL 842
Query: 262 EIETFIKAKQNSRSAENQV 280
I+AK S +QV
Sbjct: 843 -----IRAKHRSWVTTSQV 856
Score = 34.3 bits (77), Expect = 1.1
Identities = 32/144 (22%), Positives = 66/144 (45%), Gaps = 18/144 (12%)
Query: 130 RLHAAVQSVRDELEDERKLRKRSESIHRKLARELSEMKSSFTSA------LKDLEQERTR 183
RL ++ ++++LE ER+LR+R E L +L ++ A + ++ ++R
Sbjct: 32 RLEDKLRLLQEDLESERELRQRIEREKSDLTVQLMQLSDRLEEAEGSSETVVEMNKKRDT 91
Query: 184 -----RKLLEDLCDEFARGINEYEQEVHTLKQKSEKDWVQRADHDRLVLHISESWLDERM 238
RKLLED+ E E+ H L++K ++ + + L+ ER
Sbjct: 92 ELSKLRKLLEDV-------HLESEETAHHLRKKHQEAVAEMQEQMDLMTKAKSKAEKERQ 144
Query: 239 QMQLEAAQNGFMDKNSIVDKLSLE 262
+ Q E + +N+ +K++++
Sbjct: 145 KFQAEVYELLAQVENTNKEKITIQ 168
Score = 33.5 bits (75), Expect = 1.9
Identities = 76/380 (20%), Positives = 155/380 (40%), Gaps = 50/380 (13%)
Query: 40 SLDFKGRIGEPHYSLKTS--------TELLKVLNRIWSLEEQHSSNISLIKALKTELDRT 91
++D K ++ E L+ S E+ K+ + + EQ + K L +L
Sbjct: 375 NIDLKSKVEELTILLEQSQRELRQKVAEIQKLQHEYEKMREQRDALQRENKKLVDDLSEA 434
Query: 92 RIKVKELLR-------DRQADRHEVDDLMKQIAEDKLVRKSKEQ--DRLHAAVQSVRDEL 142
+ ++ + +R + + +E D+L E + +RK +E RL A + VR E
Sbjct: 435 KSQLADAIRRLHEYELEIKRLENERDELAAAYKEAETLRKQEEAKCQRLTAELAQVRHEY 494
Query: 143 EDERKLRKRSESI---HRKLARELSEMKSSFTSALKDLEQERTR-RKLLEDLCDEFARGI 198
E R+L+ + E I ++ E+ ++ A L+ E R +K + E +
Sbjct: 495 E--RRLQIKEEEIEALRKQYQLEVEQLNMRLAEAEAKLKTEIARIKKKYQAQITELEMSL 552
Query: 199 NEYEQEVHTLKQKSEKDWVQRADHDRLVLHISESWLDERMQM---QLEAAQNGFMDKNSI 255
+ ++ L++ +K +Q + L H E + ++Q QL +Q +
Sbjct: 553 DAANKQNMDLQKIIKKQAIQITE---LQAHYDE--VHRQLQQCADQLAISQRRCQGLQAE 607
Query: 256 VDKLSLEIETFIKAKQNSRSAENQVIRDRRNSLESVPLNDAVSAPQAMGDDDDDDSVGSD 315
+D+ + +E+ +++K R+AE + + E +N ++A + +
Sbjct: 608 LDEQRVALESALRSK---RAAEQSLEESQARVNELTTINVNIAAAKNKLES--------- 655
Query: 316 SHCFELNKPSHMGAKVHKE-EILDKNLDETSKSNVKKKKSVPGEGFKNHIPSNSNKKSQS 374
EL+ ++HKE ++D+ T +K K + E + +I S KKS
Sbjct: 656 ----ELSALQADYDELHKELRVVDERCQRTI-VELKSTKDILVEEQERYIKVESIKKSLE 710
Query: 375 VDAEEGLTTNIRLVEGTRIS 394
V+ L + VE ++
Sbjct: 711 VEV-RNLQVRLEEVEANALA 729
Database: sprot
Posted date: Nov 25, 2004 10:54 AM
Number of letters in database: 59,974,054
Number of sequences in database: 164,201
Lambda K H
0.317 0.131 0.368
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 73,078,065
Number of Sequences: 164201
Number of extensions: 2996190
Number of successful extensions: 15537
Number of sequences better than 10.0: 844
Number of HSP's better than 10.0 without gapping: 97
Number of HSP's successfully gapped in prelim test: 764
Number of HSP's that attempted gapping in prelim test: 13017
Number of HSP's gapped (non-prelim): 2336
length of query: 676
length of database: 59,974,054
effective HSP length: 117
effective length of query: 559
effective length of database: 40,762,537
effective search space: 22786258183
effective search space used: 22786258183
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 69 (31.2 bits)
Medicago: description of AC140913.13