BLAST2 result
BLASTP 2.2.2 [Dec-14-2001]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= AC140550.8 + phase: 0 /pseudo
(496 letters)
Database: sprot
164,201 sequences; 59,974,054 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
BRD4_MOUSE (Q9ESU6) Bromodomain-containing protein 4 (Mitotic ch... 78 6e-14
BRD4_HUMAN (O60885) Bromodomain-containing protein 4 (HUNK1 prot... 78 6e-14
YCK2_SCHPO (Q9Y7N0) Hypothetical bromodomain protein C1450.02 74 1e-12
YK82_SCHPO (Q9HGP4) Hypothetical bromodomain protein C631.02 72 3e-12
BDF1_YEAST (P35817) BDF1 protein 72 3e-12
BRD2_HUMAN (P25440) Bromodomain-containing protein 2 (RING3 prot... 71 7e-12
FSH_DROME (P13709) Female sterile homeotic protein (Fragile-chor... 69 2e-11
CBP_MOUSE (P45481) CREB-binding protein (EC 2.3.1.48) 64 7e-10
BRD3_MOUSE (Q8K2F0) Bromodomain-containing protein 3 (Bromodomai... 64 7e-10
BRD3_HUMAN (Q15059) Bromodomain-containing protein 3 (RING3-like... 64 1e-09
P300_HUMAN (Q09472) E1A-associated protein p300 (EC 2.3.1.48) 61 6e-09
CBP_HUMAN (Q92793) CREB-binding protein (EC 2.3.1.48) 61 6e-09
GCN5_YEAST (Q03330) Histone acetyltransferase GCN5 (EC 2.3.1.48) 60 2e-08
BA2B_CHICK (Q9DE13) Bromodomain adjacent to zinc finger domain 2... 58 6e-08
WDR9_HUMAN (Q9NSI6) WD-repeat protein 9 54 9e-07
CBP1_CAEEL (P34545) Protein cbp-1 54 9e-07
TAF1_HUMAN (P21675) Transcription initiation factor TFIID subuni... 53 2e-06
IE68_SHV21 (Q01042) Immediate-early protein 52 4e-06
BA2B_HUMAN (Q9UIF8) Bromodomain adjacent to zinc finger domain 2... 52 4e-06
BA1A_HUMAN (Q9NRL2) Bromodomain adjacent to zinc finger domain p... 52 4e-06
>BRD4_MOUSE (Q9ESU6) Bromodomain-containing protein 4 (Mitotic
chromosome-associated protein) (MCAP)
Length = 1400
Score = 77.8 bits (190), Expect = 6e-14
Identities = 47/132 (35%), Positives = 70/132 (52%), Gaps = 12/132 (9%)
Query: 162 NADQTSKPLPISSEIIHPKERKMPPLNPRYNKHELDTSLMIIRKVM-KMDAAEPFNVPVN 220
NA T+ P P +S P P+ ++L L ++ K + K A PF PV+
Sbjct: 39 NAASTNPPPPETSN----------PNKPKRQTNQLQYLLRVVLKTLWKHQFAWPFQQPVD 88
Query: 221 PEALGIPDYFDIIDTPMDFGTICSNLEKNDKYMNSEDVYNDVRYIWENCYKYNNKGDYIV 280
L +PDY+ II TPMD GTI LE N+ Y N+++ D ++ NCY YN GD IV
Sbjct: 89 AVKLNLPDYYKIIKTPMDMGTIKKRLE-NNYYWNAQECIQDFNTMFTNCYIYNKPGDDIV 147
Query: 281 DLMKRVKKNFMK 292
+ + ++K F++
Sbjct: 148 LMAEALEKLFLQ 159
Score = 75.1 bits (183), Expect = 4e-13
Identities = 57/197 (28%), Positives = 100/197 (49%), Gaps = 12/197 (6%)
Query: 212 AEPFNVPVNPEALGIPDYFDIIDTPMDFGTICSNLEKNDKYMNSEDVYNDVRYIWENCYK 271
A PF PV+ EALG+ DY DII PMD TI S LE + Y ++++ DVR ++ NCYK
Sbjct: 374 AWPFYKPVDVEALGLHDYCDIIKHPMDMSTIKSKLESRE-YRDAQEFGADVRLMFSNCYK 432
Query: 272 YNNKGDYIVDLMKRVKKNFMKYWAAAGLYSEQP--KGSTDFKQEESMLVESPGGEDSLSN 329
YN +V + ++++ F +A E+P S+ + +V P D S+
Sbjct: 433 YNPPDHEVVAMARKLQDVFEMRFAKMPDEPEEPVVTVSSPAVPPPTKVVAPPSSSD--SS 490
Query: 330 TDELLGTDGDVDDDKGEVTKMETSEKNCSPSDGRHEVNEVDDDGMEEENHGPEDVEEDEE 389
+D +D DD ++ E +++ + V+E + + + P+ E+D++
Sbjct: 491 SDSSSDSDSSTDD-----SEEERAQRLAELQEQLKAVHEQLAALSQPQQNKPKKKEKDKK 545
Query: 390 EDGEGEN--EEEIEMNR 404
E + ++ +EE+E N+
Sbjct: 546 EKKKEKHKKKEEVEENK 562
>BRD4_HUMAN (O60885) Bromodomain-containing protein 4 (HUNK1
protein)
Length = 1362
Score = 77.8 bits (190), Expect = 6e-14
Identities = 47/132 (35%), Positives = 70/132 (52%), Gaps = 12/132 (9%)
Query: 162 NADQTSKPLPISSEIIHPKERKMPPLNPRYNKHELDTSLMIIRKVM-KMDAAEPFNVPVN 220
NA T+ P P +S P P+ ++L L ++ K + K A PF PV+
Sbjct: 39 NAASTNPPPPETSN----------PNKPKRQTNQLQYLLRVVLKTLWKHQFAWPFQQPVD 88
Query: 221 PEALGIPDYFDIIDTPMDFGTICSNLEKNDKYMNSEDVYNDVRYIWENCYKYNNKGDYIV 280
L +PDY+ II TPMD GTI LE N+ Y N+++ D ++ NCY YN GD IV
Sbjct: 89 AVKLNLPDYYKIIKTPMDMGTIKKRLE-NNYYWNAQECIQDFNTMFTNCYIYNKPGDDIV 147
Query: 281 DLMKRVKKNFMK 292
+ + ++K F++
Sbjct: 148 LMAEALEKLFLQ 159
Score = 74.7 bits (182), Expect = 5e-13
Identities = 57/197 (28%), Positives = 100/197 (49%), Gaps = 12/197 (6%)
Query: 212 AEPFNVPVNPEALGIPDYFDIIDTPMDFGTICSNLEKNDKYMNSEDVYNDVRYIWENCYK 271
A PF PV+ EALG+ DY DII PMD TI S LE + Y ++++ DVR ++ NCYK
Sbjct: 373 AWPFYKPVDVEALGLHDYCDIIKHPMDMSTIKSKLEARE-YRDAQEFGADVRLMFSNCYK 431
Query: 272 YNNKGDYIVDLMKRVKKNFMKYWAAAGLYSEQP--KGSTDFKQEESMLVESPGGEDSLSN 329
YN +V + ++++ F +A E+P S+ + +V P D S+
Sbjct: 432 YNPPDHEVVAMARKLQDVFEMRFAKMPDEPEEPVVAVSSPAVPPPTKVVAPPSSSD--SS 489
Query: 330 TDELLGTDGDVDDDKGEVTKMETSEKNCSPSDGRHEVNEVDDDGMEEENHGPEDVEEDEE 389
+D +D DD ++ E +++ + V+E + + + P+ E+D++
Sbjct: 490 SDSSSDSDSSTDD-----SEEERAQRLAELQEQLKAVHEQLAALSQPQQNKPKKKEKDKK 544
Query: 390 EDGEGEN--EEEIEMNR 404
E + ++ +EE+E N+
Sbjct: 545 EKKKEKHKRKEEVEENK 561
>YCK2_SCHPO (Q9Y7N0) Hypothetical bromodomain protein C1450.02
Length = 578
Score = 73.6 bits (179), Expect = 1e-12
Identities = 71/303 (23%), Positives = 130/303 (42%), Gaps = 45/303 (14%)
Query: 41 DVGSKEDNNSGMEVDTPSSTGTDQHSNLANINPDGSIRKPVGRVKVKLKT--SKMLDSQP 98
D+G+ E + E P D + +N PVG + L+ + L P
Sbjct: 132 DLGTIEKKLTSYEYSVPQEFIDDMNLMFSNCFLYNGTESPVGSMGKALQEVFERQLKQLP 191
Query: 99 NSSDAPSQSDTDKSSQQQHGLERHGVNADRIEDSVTSFPDLKYGASYKKAGSIKIKSSKV 158
++ + P+ + KS Q+ S ++ P ++ S+ S+ V
Sbjct: 192 DA-EQPAAAPVKKSKQK----------------SASTAPPRT-----RRNSSVSSTSASV 229
Query: 159 LGLNADQTSKPLPISSEIIHPKERKMPPLNPRYNKHELDTSLMIIRKVMKMDA---AEPF 215
A + + P + P+ RK N ++ +++++ K A PF
Sbjct: 230 AASTAPKAASPAVLPEG--KPRRRK--------NNSQMRFCSTVLKELYKRQYESFAFPF 279
Query: 216 NVPVNPEALGIPDYFDIIDTPMDFGTICSNLEKNDKYMNSEDVYNDVRYIWENCYKYNNK 275
PV+P A PDYFD+I PMD TI S L KN+ Y E+ +D+ ++ NC+ YN
Sbjct: 280 YQPVDPVACDCPDYFDVIKEPMDLSTIQSKLNKNE-YSTLEEFESDILLMFNNCFTYNPP 338
Query: 276 GDYIVDLMKRVKKNFMKYWAAAGLYSEQPKGSTDFKQEES---MLVESPGGEDSLSNTDE 332
G + + ++++ F + W A + + +T KQ+E+ L ++ E++L + +E
Sbjct: 339 GTPVHVMGRQLENVFKEKWEARPKFDD----ATLVKQQEAETDALFDNGEEEEALMSEEE 394
Query: 333 LLG 335
+ G
Sbjct: 395 ING 397
Score = 58.2 bits (139), Expect = 5e-08
Identities = 33/107 (30%), Positives = 54/107 (49%), Gaps = 8/107 (7%)
Query: 184 MPPLNPRYNKHELDTSLMIIRKVMKMDAAEPFNVPVNPEALGIPDYFDIIDTPMDFGTIC 243
MPP +Y L I+R++ + + PF VPV+P IPDY I+ PMD GTI
Sbjct: 85 MPPPQQKY-------CLAIVRQLKRTKNSAPFKVPVDPIKQNIPDYPTIVKNPMDLGTIE 137
Query: 244 SNLEKNDKYMNSEDVYNDVRYIWENCYKYNNKGDYIVDLMKRVKKNF 290
L + Y ++ +D+ ++ NC+ YN + + K +++ F
Sbjct: 138 KKLTSYE-YSVPQEFIDDMNLMFSNCFLYNGTESPVGSMGKALQEVF 183
>YK82_SCHPO (Q9HGP4) Hypothetical bromodomain protein C631.02
Length = 727
Score = 72.4 bits (176), Expect = 3e-12
Identities = 45/134 (33%), Positives = 66/134 (48%), Gaps = 17/134 (12%)
Query: 212 AEPFNVPVNPEALGIPDYFDIIDTPMDFGTICSNLEKNDKYMNSEDVYNDVRYIWENCYK 271
A PF PVNP A G PDYF +I PMD GT+ + L N+ Y + + D+ +++NCYK
Sbjct: 413 AYPFYKPVNPTACGCPDYFKVIKHPMDLGTMQNKLNHNE-YASMKAFEADMVLMFKNCYK 471
Query: 272 YNNKGDYIVDLMKRVKKNFMKYWAAAGLYSEQPKGSTDFKQEESMLVESP------GGED 325
+N+ G + + K+++ F K WA DF E M + S G +
Sbjct: 472 FNSAGTPVHLMGKKLESIFQKLWA----------NKPDFDSETYMGMSSVNTDYYYGDNE 521
Query: 326 SLSNTDELLGTDGD 339
+ DE L DG+
Sbjct: 522 VFDSGDEFLEDDGE 535
Score = 61.6 bits (148), Expect = 4e-09
Identities = 67/296 (22%), Positives = 121/296 (40%), Gaps = 37/296 (12%)
Query: 12 PKGNTNPVSVTLTNEQEEEEEEEEETSAFDVGSK----EDNNSGMEVDTPSSTGTDQHSN 67
P + ++ L + E E+E++ + D S+ + + ++PSS H +
Sbjct: 53 PISENDDGTLDLFGDSELEKEQKGDNQETDYSSQYLHPTPPYTNFDDESPSSP---THPS 109
Query: 68 LANINPDGSIRKPVGRVKVKLKTSKMLDSQP-------NSSDAPSQSDTDKSSQQQ---- 116
++NI DG +K +++ + K+S+ LDS N D+ + S T S
Sbjct: 110 VSNITVDGDSKKHSLQLQEEEKSSESLDSHTHPPKRVRNEDDSLTFSKTSPVSPSSLKDG 169
Query: 117 --HGLERHGVNADRIEDSVTSFPDLKYGASYKKAGSIKIKSSKVLGLNADQTSKPLPISS 174
+ + N + E S ++ P AGS K SS D+T K
Sbjct: 170 ASNTVTNDASNKIKSEASESASPSALQALDSTAAGSSKEHSSP-----HDETVK------ 218
Query: 175 EIIHPKERKMPPLNPRYNKHELDTSLMIIRKVMKMDAAEPFNVPVNPEALGIPDYFDIID 234
KE P K + ++R++ + + PF PV+P IPDY II
Sbjct: 219 -----KEENDKDQYPPMTKEQHKYIHAMLRQLRRGRDSIPFRAPVDPVKQNIPDYPTIIK 273
Query: 235 TPMDFGTICSNLEKNDKYMNSEDVYNDVRYIWENCYKYNNKGDYIVDLMKRVKKNF 290
P+D GT+ + Y +++ +D+ ++ NC+ YN + + K ++ F
Sbjct: 274 NPIDLGTMQKKF-SSGVYSSAQHFIDDMNLMFSNCFLYNGTESPVGVMGKNLQATF 328
>BDF1_YEAST (P35817) BDF1 protein
Length = 686
Score = 72.4 bits (176), Expect = 3e-12
Identities = 55/192 (28%), Positives = 85/192 (43%), Gaps = 41/192 (21%)
Query: 171 PISSEIIHPKERKMPPLNPRYNKHELDTSLMIIRKVMKMDAAE-------PFNVPVNPEA 223
P S+ I+P E K P L ++ + V+K A+ PF PV+P +
Sbjct: 295 PPKSKDIYPYESKKP------KSKRLQQAMKFCQSVLKELMAKKHASYNYPFLEPVDPVS 348
Query: 224 LGIPDYFDIIDTPMDFGTICSNLEKND-KYMNSEDVYNDVRYIWENCYKYNNKGDYIVDL 282
+ +P YFD + PMD GTI L ND +Y ED DVR +++NCY +N G + +
Sbjct: 349 MNLPTYFDYVKEPMDLGTIAKKL--NDWQYQTMEDFERDVRLVFKNCYTFNPDGTIVNMM 406
Query: 283 MKRVKKNFMKYWAAAGLYSEQPKGSTDFKQEESMLVESPGGEDSLSNTDELLGTDGDVDD 342
R+++ F WA + P +D ++DE T GD DD
Sbjct: 407 GHRLEEVFNSKWA-----------------------DRPNLDD--YDSDEDSRTQGDYDD 441
Query: 343 DKGEVTKMETSE 354
+ E ++ + E
Sbjct: 442 YESEYSESDIDE 453
Score = 60.5 bits (145), Expect = 1e-08
Identities = 69/283 (24%), Positives = 114/283 (39%), Gaps = 29/283 (10%)
Query: 56 TPSSTGTDQHSNLANINPDGSIRKPVGRVKVKLKTSKMLDSQPNSSD-----APSQSDTD 110
TP D + N N + ++++P+ + S L + N ++ ++ D D
Sbjct: 5 TPVQNDVDVNGNNVNDDVSSNLKRPIDQGD----PSNGLAEEENPANNQLHLKKARLDGD 60
Query: 111 KSSQQQHGLERHGVN-ADRIEDSVTSFPDLKYGASYKKAGSIKIKSSK-VLGLNADQTSK 168
+ GL +G+ A + + GA ++ G K + + + D+ SK
Sbjct: 61 ALTSSPAGLAENGIEGATLAANGENGYNATGSGAEDEQQGLKKEEGGQGTKQEDLDENSK 120
Query: 169 P-LPISSEIIHPKE-RKMPPLNPRYN--------KHELDTSLMIIRKVMKMDAAEPFNVP 218
LP+ PKE PP P N KH+ +L+ I+ V ++ A PF P
Sbjct: 121 QELPMEV----PKEPAPAPPPEPDMNNLPQNPIPKHQQKHALLAIKAVKRLKDARPFLQP 176
Query: 219 VNPEALGIPDYFDIIDTPMDFGTICSNLEKNDKYMNSEDVYNDVRYIWENCYKYNNKGDY 278
V+P L IP YF+ I PMD TI L Y E + D + N K+N
Sbjct: 177 VDPVKLDIPFYFNYIKRPMDLSTIERKLNVG-AYEVPEQITEDFNLMVNNSIKFNGPNAG 235
Query: 279 IVDLMKRVKKNFMKYWAAAGLYSEQP---KGSTDFKQEESMLV 318
I + + ++ +F K+ P KG QE++ +V
Sbjct: 236 ISQMARNIQASFEKHMLNMPAKDAPPVIAKGRRSSAQEDAPIV 278
>BRD2_HUMAN (P25440) Bromodomain-containing protein 2 (RING3
protein) (O27.1.1)
Length = 801
Score = 70.9 bits (172), Expect = 7e-12
Identities = 53/206 (25%), Positives = 95/206 (45%), Gaps = 9/206 (4%)
Query: 212 AEPFNVPVNPEALGIPDYFDIIDTPMDFGTICSNLEKNDKYMNSEDVYNDVRYIWENCYK 271
A PF PV+ ALG+ DY DII PMD T+ +E D Y ++++ DVR ++ NCYK
Sbjct: 369 AWPFYKPVDASALGLHDYHDIIKHPMDLSTVKRKMENRD-YRDAQEFAADVRLMFSNCYK 427
Query: 272 YNNKGDYIVDLMKRVKKNFMKYWAAAGLYSEQPKGSTDFKQEESMLVESPGGEDSLSNTD 331
YN +V + ++++ F +A +P L +S S ++
Sbjct: 428 YNPPDHDVVAMARKLQDVFEFRYAKMPDEPLEPGPLPVSTAMPPGLAKSSSESSSEESSS 487
Query: 332 ELLGTDGDVDDDKGEVTKMETSEKNCSPSDGRHEVNEVDD------DGMEEENHGPEDVE 385
E + + +D++ E + E SE + S + H + E+ + + + + GP
Sbjct: 488 ESSSEEEEEEDEEDE--EEEESESSDSEEERAHRLAELQEQLRAVHEQLAALSQGPISKP 545
Query: 386 EDEEEDGEGENEEEIEMNRVKRRMDE 411
+ + E E + + + E +R + DE
Sbjct: 546 KRKREKKEKKKKRKAEKHRGRAGADE 571
Score = 63.5 bits (153), Expect = 1e-09
Identities = 34/92 (36%), Positives = 52/92 (55%), Gaps = 1/92 (1%)
Query: 201 MIIRKVMKMDAAEPFNVPVNPEALGIPDYFDIIDTPMDFGTICSNLEKNDKYMNSEDVYN 260
++++ + K A PF PV+ LG+PDY II PMD GTI LE N+ Y + +
Sbjct: 85 VVMKALWKHQFAWPFRQPVDAVKLGLPDYHKIIKQPMDMGTIKRRLE-NNYYWAASECMQ 143
Query: 261 DVRYIWENCYKYNNKGDYIVDLMKRVKKNFMK 292
D ++ NCY YN D IV + + ++K F++
Sbjct: 144 DFNTMFTNCYIYNKPTDDIVLMAQTLEKIFLQ 175
>FSH_DROME (P13709) Female sterile homeotic protein (Fragile-chorion
membrane protein)
Length = 2038
Score = 69.3 bits (168), Expect = 2e-11
Identities = 40/122 (32%), Positives = 66/122 (53%), Gaps = 8/122 (6%)
Query: 172 ISSEIIHPKERKMPPLNPRYNKHELDTSLMIIRKVM-KMDAAEPFNVPVNPEALGIPDYF 230
+ +I P ER P N ++L + + KV+ K + PF PV+ + L +PDY
Sbjct: 21 VQPPVIPPAER------PGRNTNQLQYLIKTVMKVIWKHHFSWPFQQPVDAKKLNLPDYH 74
Query: 231 DIIDTPMDFGTICSNLEKNDKYMNSEDVYNDVRYIWENCYKYNNKGDYIVDLMKRVKKNF 290
II PMD GTI LE N+ Y ++++ D ++ NCY YN G+ +V + + ++K F
Sbjct: 75 KIIKQPMDMGTIKKRLE-NNYYWSAKETIQDFNTMFNNCYVYNKPGEDVVVMAQTLEKVF 133
Query: 291 MK 292
++
Sbjct: 134 LQ 135
Score = 65.1 bits (157), Expect = 4e-10
Identities = 39/110 (35%), Positives = 61/110 (55%), Gaps = 9/110 (8%)
Query: 192 NKHELDTSLMIIRKVMK-------MDAAEPFNVPVNPEALGIPDYFDIIDTPMDFGTICS 244
NK +L +L +++K A PF PV+ E LG+ DY DII PMD GT+
Sbjct: 473 NKEKLSDALKSCNEILKELFSKKHSGYAWPFYKPVDAEMLGLHDYHDIIKKPMDLGTVKR 532
Query: 245 NLEKNDKYMNSEDVYNDVRYIWENCYKYNNKGDYIVDLMKRVKKNF-MKY 293
++ N +Y ++ + DVR I+ NCYKYN +V + ++++ F M+Y
Sbjct: 533 KMD-NREYKSAPEFAADVRLIFTNCYKYNPPDHDVVAMGRKLQDVFEMRY 581
>CBP_MOUSE (P45481) CREB-binding protein (EC 2.3.1.48)
Length = 2441
Score = 64.3 bits (155), Expect = 7e-10
Identities = 59/246 (23%), Positives = 101/246 (40%), Gaps = 41/246 (16%)
Query: 54 VDTPSSTGTDQHSNLANINPDGSIRKPVGRVKVKLKTSKMLDSQPNSSDAPSQSDTDKSS 113
V TPS T T ++ PD P+ +K +++T D++P +++ + ++
Sbjct: 973 VPTPS-TVTSAETSSQQPGPD----VPMLEMKTEVQTD---DAEPEPTESKGEPRSEMME 1024
Query: 114 QQQHGLERHGVNADRIEDSVTSF------PDLKYGASYKKAGSIKIKSSKVLGLNADQTS 167
+ G + D E P++K A ++ S +S Q++
Sbjct: 1025 EDLQGSSQVKEETDTTEQKSEPMEVEEKKPEVKVEAKEEEENSSNDTAS--------QST 1076
Query: 168 KPLPISSEIIHPKERK---MPPLNPRYNKHELDTSLMIIRKVMKMDAAEPFNVPVNPEAL 224
P +I P+E + MP L Y + + PF PV+P+ L
Sbjct: 1077 SPSQPRKKIFKPEELRQALMPTLEALYRQDP---------------ESLPFRQPVDPQLL 1121
Query: 225 GIPDYFDIIDTPMDFGTICSNLEKNDKYMNSEDVYNDVRYIWENCYKYNNKGDYIVDLMK 284
GIPDYFDI+ PMD TI L+ +Y +DVR ++ N + YN K +
Sbjct: 1122 GIPDYFDIVKNPMDLSTIKRKLD-TGQYQEPWQYVDDVRLMFNNAWLYNRKTSRVYKFCS 1180
Query: 285 RVKKNF 290
++ + F
Sbjct: 1181 KLAEVF 1186
>BRD3_MOUSE (Q8K2F0) Bromodomain-containing protein 3
(Bromodomain-containing FSH-like protein FSRG2)
Length = 726
Score = 64.3 bits (155), Expect = 7e-10
Identities = 54/258 (20%), Positives = 114/258 (43%), Gaps = 10/258 (3%)
Query: 212 AEPFNVPVNPEALGIPDYFDIIDTPMDFGTICSNLEKNDKYMNSEDVYNDVRYIWENCYK 271
A PF PV+ EAL + DY DII PMD T+ ++ + Y +++ D+R ++ NCYK
Sbjct: 330 AWPFYKPVDAEALELHDYHDIIKHPMDLSTVKRKMDSRE-YPDAQGFAADIRLMFSNCYK 388
Query: 272 YNNKGDYIVDLMKRVKKNFMKYWAAAGLYSEQPKGSTDFKQEESMLVESPGGEDSLSNTD 331
YN +V + ++++ F +A ++P + + +V G +S +++
Sbjct: 389 YNPPDHEVVAMARKLQDVFEMRFAK---MPDEPMEAPALPAPTAPIVSK--GAESSRSSE 443
Query: 332 ELLGTDGDVDDDKGEVTKM-ETSEKNCSPSDGRHEVNE--VDDDGMEEENHGPEDVEEDE 388
E G D ++ T++ E E+ + + +++ V+ ++E E ++D+
Sbjct: 444 ESSSDSGSSDSEEERATRLAELQEQLKAVHEQLAALSQAPVNKPKKKKEKKEKEKKKKDK 503
Query: 389 EEDGEGENEEEIEMNRVKRRMDETLRHG-GTLAEESEVGDTAALHDEYKNTQQEGQAAVV 447
++D E E + K + + A + T + K ++ A+
Sbjct: 504 DKDKEKEKHKAKSEEEKKAKAAPAAKQAQQKKAPTKKANSTTTASRQLKKGGKQASASYD 563
Query: 448 QQQKKHKEPQDKHQKAKL 465
++++ P +K +L
Sbjct: 564 SEEEEEGLPMSYDEKRQL 581
Score = 62.8 bits (151), Expect = 2e-09
Identities = 33/92 (35%), Positives = 52/92 (55%), Gaps = 1/92 (1%)
Query: 201 MIIRKVMKMDAAEPFNVPVNPEALGIPDYFDIIDTPMDFGTICSNLEKNDKYMNSEDVYN 260
++++ + K A PF PV+ L +PDY II PMD GTI LE N+ Y ++ +
Sbjct: 44 VVVKTLWKHQFAWPFYQPVDAIKLNLPDYHKIIKNPMDMGTIKKRLE-NNYYWSASECMQ 102
Query: 261 DVRYIWENCYKYNNKGDYIVDLMKRVKKNFMK 292
D ++ NCY YN D IV + + ++K F++
Sbjct: 103 DFNTMFTNCYIYNKPTDDIVLMAQALEKIFLQ 134
>BRD3_HUMAN (Q15059) Bromodomain-containing protein 3 (RING3-like
protein)
Length = 726
Score = 63.5 bits (153), Expect = 1e-09
Identities = 49/195 (25%), Positives = 92/195 (47%), Gaps = 11/195 (5%)
Query: 212 AEPFNVPVNPEALGIPDYFDIIDTPMDFGTICSNLEKNDKYMNSEDVYNDVRYIWENCYK 271
A PF PV+ EAL + DY DII PMD T+ ++ + Y +++ DVR ++ NCYK
Sbjct: 331 AWPFYKPVDAEALELHDYHDIIKHPMDLSTVKRKMDGRE-YPDAQGFAADVRLMFSNCYK 389
Query: 272 YNNKGDYIVDLMKRVKKNFMKYWAAAGLYSEQPKGSTDFKQEESMLVESPGGEDSLSNTD 331
YN +V + ++++ F +A ++P + + +V G +S +++
Sbjct: 390 YNPPDHEVVAMARKLQDVFEMRFAK---MPDEPVEAPALPAPAAPMVSK--GAESSRSSE 444
Query: 332 ELLGTDGDVDDDKGEVTKMETSEKNCSPSDGRHEVNEVDDDGMEEENHGPEDVEEDEEED 391
E G D ++ T++ ++ HE ++ N + E+ E+E
Sbjct: 445 ESSSDSGSSDSEEERATRLAELQEQLK---AVHE--QLAALSQAPVNKPKKKKEKKEKEK 499
Query: 392 GEGENEEEIEMNRVK 406
+ + E+E E ++VK
Sbjct: 500 KKKDKEKEKEKHKVK 514
Score = 62.8 bits (151), Expect = 2e-09
Identities = 33/92 (35%), Positives = 52/92 (55%), Gaps = 1/92 (1%)
Query: 201 MIIRKVMKMDAAEPFNVPVNPEALGIPDYFDIIDTPMDFGTICSNLEKNDKYMNSEDVYN 260
++++ + K A PF PV+ L +PDY II PMD GTI LE N+ Y ++ +
Sbjct: 45 VVVKTLWKHQFAWPFYQPVDAIKLNLPDYHKIIKNPMDMGTIKKRLE-NNYYWSASECMQ 103
Query: 261 DVRYIWENCYKYNNKGDYIVDLMKRVKKNFMK 292
D ++ NCY YN D IV + + ++K F++
Sbjct: 104 DFNTMFTNCYIYNKPTDDIVLMAQALEKIFLQ 135
>P300_HUMAN (Q09472) E1A-associated protein p300 (EC 2.3.1.48)
Length = 2414
Score = 61.2 bits (147), Expect = 6e-09
Identities = 48/225 (21%), Positives = 94/225 (41%), Gaps = 25/225 (11%)
Query: 71 INPDGSIRKPVGRVKVKLKTSKMLDSQPNSSDAPSQSDTDKSSQQQHGLERHGVNADRIE 130
++ +G + P ++ + + + QP S + ++ + + + ++ ++E
Sbjct: 945 VSIEGQVSNPPSTSSTEVNSQAIAEKQP-SQEVKMEAKMEVDQPEPADTQPEDISESKVE 1003
Query: 131 DSVTSFPDLKYGASYKKAGSIKIKSSKVLGLNADQTSKPLPISSE--IIHPKERK---MP 185
D + + ++ K +IK + + S P P S+ I P+E + MP
Sbjct: 1004 DCKMESTETEERSTELKT---EIKEEEDQPSTSATQSSPAPGQSKKKIFKPEELRQALMP 1060
Query: 186 PLNPRYNKHELDTSLMIIRKVMKMDAAEPFNVPVNPEALGIPDYFDIIDTPMDFGTICSN 245
L Y + + PF PV+P+ LGIPDYFDI+ +PMD TI
Sbjct: 1061 TLEALYRQDP---------------ESLPFRQPVDPQLLGIPDYFDIVKSPMDLSTIKRK 1105
Query: 246 LEKNDKYMNSEDVYNDVRYIWENCYKYNNKGDYIVDLMKRVKKNF 290
L+ +Y +D+ ++ N + YN K + ++ + F
Sbjct: 1106 LD-TGQYQEPWQYVDDIWLMFNNAWLYNRKTSRVYKYCSKLSEVF 1149
>CBP_HUMAN (Q92793) CREB-binding protein (EC 2.3.1.48)
Length = 2442
Score = 61.2 bits (147), Expect = 6e-09
Identities = 59/243 (24%), Positives = 99/243 (40%), Gaps = 35/243 (14%)
Query: 54 VDTPSSTGTDQHSNLANINPDGSIRKPVGRVKVKLKTSKMLDSQPNSSDAPSQSDTDKSS 113
V TPSS + + +N PD PV +K + + D++P+ ++ + ++
Sbjct: 972 VPTPSSVASAE-TNSQQPGPD----VPVLEMKTETQAE---DTEPDPGESKGEPRSEMME 1023
Query: 114 QQQHGLERHGVNADRIEDSVTSFP-DLKYGASYKKAGSIKIKSSKVLGLN--ADQTSKPL 170
+ G + D E D K K +++K + N A Q++ P
Sbjct: 1024 EDLQGASQVKEETDIAEQKSEPMEVDEK-----KPEVKVEVKEEEESSSNGTASQSTSPS 1078
Query: 171 PISSEIIHPKERK---MPPLNPRYNKHELDTSLMIIRKVMKMDAAEPFNVPVNPEALGIP 227
+I P+E + MP L Y + + PF PV+P+ LGIP
Sbjct: 1079 QPRKKIFKPEELRQALMPTLEALYRQDP---------------ESLPFRQPVDPQLLGIP 1123
Query: 228 DYFDIIDTPMDFGTICSNLEKNDKYMNSEDVYNDVRYIWENCYKYNNKGDYIVDLMKRVK 287
DYFDI+ PMD TI L+ +Y +DV ++ N + YN K + ++
Sbjct: 1124 DYFDIVKNPMDLSTIKRKLD-TGQYQEPWQYVDDVWLMFNNAWLYNRKTSRVYKFCSKLA 1182
Query: 288 KNF 290
+ F
Sbjct: 1183 EVF 1185
>GCN5_YEAST (Q03330) Histone acetyltransferase GCN5 (EC 2.3.1.48)
Length = 439
Score = 59.7 bits (143), Expect = 2e-08
Identities = 34/89 (38%), Positives = 45/89 (50%), Gaps = 3/89 (3%)
Query: 202 IIRKVMKMDAAEPFNVPVNPEALGIPDYFDIIDTPMDFGTICSNLEKNDKYMNSEDVYND 261
I+ ++ AA PF PVN E +PDY+D I PMD T+ LE N KY ED D
Sbjct: 339 ILTELQNHAAAWPFLQPVNKEE--VPDYYDFIKEPMDLSTMEIKLESN-KYQKMEDFIYD 395
Query: 262 VRYIWENCYKYNNKGDYIVDLMKRVKKNF 290
R ++ NC YN + R++K F
Sbjct: 396 ARLVFNNCRMYNGENTSYYKYANRLEKFF 424
>BA2B_CHICK (Q9DE13) Bromodomain adjacent to zinc finger domain 2B
(Extracellular matrix protein F22)
Length = 2130
Score = 57.8 bits (138), Expect = 6e-08
Identities = 54/184 (29%), Positives = 80/184 (43%), Gaps = 22/184 (11%)
Query: 111 KSSQQQHGLERHGVNADRIEDSVTSFPDLKYGASYKKAGSIKIKSSKVLGLNADQTSKPL 170
KS++Q+ G + G D EDS T+ LK G + K + S G + T+
Sbjct: 1962 KSNEQKRGRKLPGDTED--EDSATTSTSLKRGKTEPKKRKMDESVSVSQGKQENFTA--- 2016
Query: 171 PISSEIIHPKERKMPPLNPRYNKHELDTSLMIIRKVMKMDAAEPFNVPVNPEALGIPDYF 230
I PK R + +L MI+ ++ + A PF +PVN + +P Y
Sbjct: 2017 -----IKKPK---------RDDSKDLAICSMILSELETHEDAWPFLLPVNLKL--VPGYK 2060
Query: 231 DIIDTPMDFGTICSNLEKNDKYMNSEDVYNDVRYIWENCYKYNNKGDYIVDLMKRVKKNF 290
+I PMDF TI L +Y N E DVR +++NC +N I ++K F
Sbjct: 2061 KVIKKPMDFSTIRDKLTSG-QYPNVEAFSLDVRLVFDNCETFNEDDSDIGRAGHNMRKYF 2119
Query: 291 MKYW 294
K W
Sbjct: 2120 EKKW 2123
Score = 42.4 bits (98), Expect = 0.003
Identities = 36/144 (25%), Positives = 57/144 (39%), Gaps = 13/144 (9%)
Query: 329 NTDELLGTDGDVDDDKGEVTKMETSEKNCSPSDGRHE------VNEVDDDGMEEENHGPE 382
N +LL T D DK K S N G ++ D D +EE+ E
Sbjct: 160 NKVQLLDTRADKIKDKKPRKKAVESSSNSDSDSGSSSDTSSEGISSSDSDDLEEDEEEEE 219
Query: 383 DVEEDEEEDGEGENEEEIEMNRVKRRMDETLRHGGTLAEESEVGDTAALHDEYKNTQQEG 442
D +E ED E ++E E ++ L H G +++ G A + K T Q
Sbjct: 220 DQSAEESEDDESDSENEAH----HENKNKVLMHSGVKDMKTD-GQKAHEKSQEKRTHQ-- 272
Query: 443 QAAVVQQQKKHKEPQDKHQKAKLL 466
Q +V + H Q + ++ ++L
Sbjct: 273 QIPLVSDSQTHSSFQSQQKQPQVL 296
Score = 37.4 bits (85), Expect = 0.090
Identities = 29/111 (26%), Positives = 54/111 (48%), Gaps = 20/111 (18%)
Query: 319 ESPGGEDSLSNTDELLGTDGDVDDDKGEVTKMETSEKNCSPSDGRHEVNEVDDDGMEEEN 378
++P ++S + D D D D+D+ E + + S+ + S SD +E D DG E+E+
Sbjct: 546 DAPSSKESDDSND-----DDDDDEDEDEDDEDDDSDDSQSESDSN---SESDTDGSEDED 597
Query: 379 HGPEDVEEDEEEDGEGENEEEIEMNRVKRRMDETLRHGGTLAEESEVGDTA 429
+ED+++ E + + E E +K L+ G+ + S +G A
Sbjct: 598 ------DEDDKDQDESDTDTEGEKTPLK------LKKTGSSIKSSSIGPVA 636
Score = 33.1 bits (74), Expect = 1.7
Identities = 72/400 (18%), Positives = 150/400 (37%), Gaps = 32/400 (8%)
Query: 19 VSVTLTNEQEEEEEEEEETSAFDVGSKEDNNSGMEVDTPSSTGTDQHSNLANINPDGSIR 78
+S + +++ EE+EEEEE+ SA + ++++S E + HS + ++ DG
Sbjct: 203 ISSSDSDDLEEDEEEEEDQSA-EESEDDESDSENEAHHENKNKVLMHSGVKDMKTDGQKA 261
Query: 79 KPVGRVK-VKLKTSKMLDSQPNSSDAPSQSDTDKSSQQ-----------QHGLERHGVNA 126
+ K + + DSQ +SS Q SQQ + + +H +
Sbjct: 262 HEKSQEKRTHQQIPLVSDSQTHSSFQSQQKQPQVLSQQLPFIFQSSQAKEESVNKH-TSV 320
Query: 127 DRIEDSVTSFPDLKYGASYKKAGSIKI---KSSKVLGLNADQTSKPLPISSEIIHPKERK 183
+ V + L KK +KI + N + + + +P+ S+ + K +
Sbjct: 321 IQSTGLVPNVKPLSLVHQTKKEAYLKIIVPPPDLLKAGNKNTSEESIPLISD-VRSKREQ 379
Query: 184 MPPLNPRYNKHELDTSLMIIRKVMKMDAAEPFNVPVNPEALGIPDYFDIIDTPMDFGTIC 243
P + ++S + + + + +++P +P + + P +
Sbjct: 380 YKQTFPAAQLKKQESSKNLKKVIASLSSSKP--TSCSPAHQKLTSLENNHSNPFLTNALL 437
Query: 244 SNLEKNDKYMNSEDVYNDVRYIWENCYKYNNKGDYIVDLMKRVKKNFMKYWAAAGLYSEQ 303
N + N + V +V K K + V + + +A G ++
Sbjct: 438 GNHQPNGVI---QSVIQEVPLALTTKQKSQTKINESVAIASSTPFSLPVNLSACG---KK 491
Query: 304 PKGSTDFKQEESMLVESPGGEDS--LSNTDELLGTDGDVDDDKGEVTKMETSEKNCSPSD 361
G+ + V G+D +N + T + K V + + + S
Sbjct: 492 TTGNRTLVVPSTSPVLPGSGKDKPVSNNAVNAVKTQHCLPSAKLVVEQFRGVDSDAPSSK 551
Query: 362 GRHEVNEVDDDGMEEENHGPEDVEEDEEEDGEGENEEEIE 401
+ N+ DDD +E+ ED E+D+ +D + E++ E
Sbjct: 552 ESDDSNDDDDDDEDED----EDDEDDDSDDSQSESDSNSE 587
Score = 32.0 bits (71), Expect = 3.8
Identities = 18/73 (24%), Positives = 35/73 (47%)
Query: 310 FKQEESMLVESPGGEDSLSNTDELLGTDGDVDDDKGEVTKMETSEKNCSPSDGRHEVNEV 369
F+ +S S +DS + D+ D D +DD + ++ E+ + S +DG + ++
Sbjct: 540 FRGVDSDAPSSKESDDSNDDDDDDEDEDEDDEDDDSDDSQSESDSNSESDTDGSEDEDDE 599
Query: 370 DDDGMEEENHGPE 382
DD +E + E
Sbjct: 600 DDKDQDESDTDTE 612
Score = 31.6 bits (70), Expect = 4.9
Identities = 28/110 (25%), Positives = 47/110 (42%), Gaps = 6/110 (5%)
Query: 5 RGHKKGRPKGNTNPVSVTLTNEQEEEEEEEEETSAFDVGSKEDNNSGMEVDTPSSTGTDQ 64
RG P + S ++ E+E+E++E+ + D S+ D+NS + D G++
Sbjct: 541 RGVDSDAPSSKESDDSNDDDDDDEDEDEDDEDDDSDDSQSESDSNSESDTD-----GSED 595
Query: 65 HSNLANINPDGSIRKPVGRVKVKLKTSKMLDSQPNSSDAPSQSDTDKSSQ 114
+ + + D S G K LK K S +SS P T + Q
Sbjct: 596 EDDEDDKDQDESDTDTEGE-KTPLKLKKTGSSIKSSSIGPVAHSTPLNLQ 644
>WDR9_HUMAN (Q9NSI6) WD-repeat protein 9
Length = 2269
Score = 53.9 bits (128), Expect = 9e-07
Identities = 55/237 (23%), Positives = 101/237 (42%), Gaps = 32/237 (13%)
Query: 202 IIRKVMKMDAAEPFNVPVNPEALGIPDYFDIIDTPMDFGTICSNLEKNDKYMNSEDVYND 261
++ + + + +EPF PV + + PDY DIIDTPMDFGT+ L+ + Y + + D
Sbjct: 1325 LVNLIFQCEDSEPFRQPV--DLVEYPDYRDIIDTPMDFGTVRETLDAGN-YDSPLEFCKD 1381
Query: 262 VRYIWENCYKYN-NKGDYIVDLMKRVK-------KNFMKYWAAAGLYSEQPKGSTDFKQE 313
+R I+ N Y NK I + R+ K + ++E+ + S FKQ
Sbjct: 1382 IRLIFSNAKAYTPNKRSKIYSMTLRLSALFEEKMKKISSDFKIGQKFNEKLRRSQRFKQR 1441
Query: 314 ESMLVESPGGEDSLSNTDELLGTDGDVDDDKGEVTKMETSEKNCSPSDGRHEVNEVDDDG 373
++ +S + + + L + + + TS + G H+ + G
Sbjct: 1442 QNCKGDSQPNKSIRNLKPKRLKSQTKIIPELVGSPTQSTSSRTAYL--GTHKTSAGISSG 1499
Query: 374 MEEENHGPEDVEEDEEEDGEGENEEEIEMNRVKRRMDETLRHGGTLAEESEVGDTAA 430
+ G++ + E + +R+ + + +G TL+ ESEV D+ A
Sbjct: 1500 VT-----------------SGDSSDSAESSE-RRKRNRPITNGSTLS-ESEVEDSLA 1537
>CBP1_CAEEL (P34545) Protein cbp-1
Length = 2056
Score = 53.9 bits (128), Expect = 9e-07
Identities = 29/92 (31%), Positives = 48/92 (51%), Gaps = 1/92 (1%)
Query: 200 LMIIRKVMKMDAAEPFNVPVNPEALGIPDYFDIIDTPMDFGTICSNLEKNDKYMNSEDVY 259
L + K+ K + A PF VPV+ + L IPDY +II PMD T+ L +Y N+
Sbjct: 874 LPVWEKLDKSEDAAPFRVPVDAKLLNIPDYHEIIKRPMDLETVHKKLYAG-QYQNAGQFC 932
Query: 260 NDVRYIWENCYKYNNKGDYIVDLMKRVKKNFM 291
+D+ + +N + YN K + ++ + F+
Sbjct: 933 DDIWLMLDNAWLYNRKNSKVYKYGLKLSEMFV 964
>TAF1_HUMAN (P21675) Transcription initiation factor TFIID subunit 1
(EC 2.7.1.37) (Transcription initiation factor TFIID 250
kDa subunit) (TAF(II)250) (TAFII-250) (TAFII250)
(TBP-associated factor 250 kDa) (p250) (Cell cycle gene 1
protein)
Length = 1872
Score = 52.8 bits (125), Expect = 2e-06
Identities = 63/265 (23%), Positives = 112/265 (41%), Gaps = 61/265 (23%)
Query: 201 MIIRKVMKMDAAEPFNVPVNPEALGIPDYFDIIDTPMDFGTICSNLEKNDKYMNSEDVYN 260
++ +K+M + + PF+ PVN + +PDY+ +I PMD TI N+ K+ KY + E +
Sbjct: 1514 IVTQKMMAVPDSWPFHHPVNKKF--VPDYYKVIVNPMDLETIRKNISKH-KYQSRESFLD 1570
Query: 261 DVRYIWENCYKYN-------NKGDYIVDL-----------MKRVKKNFMKYWAAA----- 297
DV I N KYN IV++ + +++K+ AA
Sbjct: 1571 DVNLILANSVKYNGPESQYTKTAQEIVNVCYQTLTEYDEHLTQLEKDICTAKEAALEEAE 1630
Query: 298 ---------GLYSEQP-------------KGSTDFKQEESM-LVESPGGEDSLSNTDELL 334
G Y+ QP + ++ F+ E +M +++ P T E
Sbjct: 1631 LESLDPMTPGPYTPQPPDLYDTNTSLSMSRDASVFQDESNMSVLDIPSATPEKQVTQEGE 1690
Query: 335 GTDGDV-DDDKGEVTKMETS--EKNCSPSDGRHEVNEVDDDGMEEENHGP------EDVE 385
DGD+ D+++G V + + S ++ S+G ++ +D G +EE P +
Sbjct: 1691 DGDGDLADEEEGTVQQPQASVLYEDLLMSEGE---DDEEDAGSDEEGDNPFSAIQLSESG 1747
Query: 386 EDEEEDGEGENEEEIEMNRVKRRMD 410
D + G ++ M + RMD
Sbjct: 1748 SDSDVGSGGIRPKQPRMLQENTRMD 1772
Score = 38.1 bits (87), Expect = 0.053
Identities = 23/72 (31%), Positives = 35/72 (47%), Gaps = 3/72 (4%)
Query: 202 IIRKVMKMDAAEPFNVPVNPEALGIPDYFDIIDTPMDFGTICSNLEKNDKYMNSEDVYND 261
II + + PF+ PVN + + DY+ II PMD T+ N+ K Y + E+
Sbjct: 1392 IINDMRDLPNTYPFHTPVNAKV--VKDYYKIITRPMDLQTLRENVRKR-LYPSREEFREH 1448
Query: 262 VRYIWENCYKYN 273
+ I +N YN
Sbjct: 1449 LELIVKNSATYN 1460
Score = 32.7 bits (73), Expect = 2.2
Identities = 33/109 (30%), Positives = 51/109 (46%), Gaps = 16/109 (14%)
Query: 296 AAGLYSEQPK-----GSTDFKQEESML-VESPGGEDSLSNTDELLGTDGDVDDDKGEVTK 349
+ G+ +QP+ D + EESM+ E GGE S D + + D K
Sbjct: 1754 SGGIRPKQPRMLQENTRMDMENEESMMSYEGDGGEASHGLEDSNISYGSYEEPDP----K 1809
Query: 350 METSEKNCSPSDGRHEVNEVDDDGMEEENH-GPEDVEE----DEEEDGE 393
T + + S S G +EV+E ++D EEE GP + + ++EED E
Sbjct: 1810 SNTQDTSFS-SIGGYEVSEEEEDEEEEEQRSGPSVLSQVHLSEDEEDSE 1857
>IE68_SHV21 (Q01042) Immediate-early protein
Length = 407
Score = 52.0 bits (123), Expect = 4e-06
Identities = 41/171 (23%), Positives = 71/171 (40%), Gaps = 9/171 (5%)
Query: 302 EQPKGSTDFKQEESMLVESPGGEDSLSNTDELLGTDGDVDDDKGEVTKMETSEKNCSPSD 361
+Q T+ ++ E VE G E +E G G+ + + E + E EK +
Sbjct: 53 QQQAALTEEQRREE--VEEEGEERERRGEEEREGEGGEEGEGREEAEEEEAEEKEAEEEE 110
Query: 362 GRH-----EVNEVDDDGMEEENHGPEDVEEDEEEDGEGENEEEIEMNRVKRRMDETLRHG 416
E E ++ EEE E+ EE+E E+ E E EE E + +E
Sbjct: 111 AEEAEEEAEEEEAEEAEAEEEEAEEEEAEEEEAEEAEEEEAEEAEEEAEEEEAEEEAEEE 170
Query: 417 GTLAEESEVGDTAALHDEYKNTQQEGQAAVVQQQKKHKEPQDKHQKAKLLE 467
AEE+E + A E +E + A + ++ +E ++ ++A+ E
Sbjct: 171 AEEAEEAE--EEAEEEAEEAEEAEEAEEAEEEAEEAEEEAEEAEEEAEEAE 219
Score = 44.7 bits (104), Expect = 6e-04
Identities = 32/156 (20%), Positives = 66/156 (41%), Gaps = 5/156 (3%)
Query: 302 EQPKGSTDFKQEES--MLVESPGGEDSLSNTDELLGTDGDVDDDKGEVTKMETSEKNCSP 359
E+ +G + ++EE+ E E++ +E + + ++++ E + E E +
Sbjct: 88 EEGEGREEAEEEEAEEKEAEEEEAEEAEEEAEEEEAEEAEAEEEEAEEEEAEEEEAEEAE 147
Query: 360 SDGRHEVNEVDDDGMEEENHGPEDVEEDEEEDGEGENEEEIEMNRVKRRMDETLRHGGTL 419
+ E E +++ EEE + E +E E+ E E EEE E +E
Sbjct: 148 EE---EAEEAEEEAEEEEAEEEAEEEAEEAEEAEEEAEEEAEEAEEAEEAEEAEEEAEEA 204
Query: 420 AEESEVGDTAALHDEYKNTQQEGQAAVVQQQKKHKE 455
EE+E + A E +E + + +++ +E
Sbjct: 205 EEEAEEAEEEAEEAEEAEEAEEAEEEAEEAEEEEEE 240
Score = 40.0 bits (92), Expect = 0.014
Identities = 34/157 (21%), Positives = 67/157 (42%), Gaps = 15/157 (9%)
Query: 319 ESPGGEDS--LSNTDELLGTDGDVDDDKGEVTKMETSEKNCSPSDGRHEV--------NE 368
E GGE+ +E + + ++++ E + E E+ ++ E E
Sbjct: 83 EGEGGEEGEGREEAEEEEAEEKEAEEEEAEEAEEEAEEEEAEEAEAEEEEAEEEEAEEEE 142
Query: 369 VDDDGMEEENHGPEDVEEDE-EEDGEGENEEEIEMNRVKRRMDETLRHGGTLAEESEVGD 427
++ EE E+ EE+E EE+ E E EE E E AEE+E +
Sbjct: 143 AEEAEEEEAEEAEEEAEEEEAEEEAEEEAEEAEEAEEEAEEEAEEAEE----AEEAEEAE 198
Query: 428 TAALHDEYKNTQQEGQAAVVQQQKKHKEPQDKHQKAK 464
A E + + E +A ++ ++ +E +++ ++A+
Sbjct: 199 EEAEEAEEEAEEAEEEAEEAEEAEEAEEAEEEAEEAE 235
Score = 34.7 bits (78), Expect = 0.58
Identities = 41/199 (20%), Positives = 78/199 (38%), Gaps = 13/199 (6%)
Query: 302 EQPKGSTDFKQEESMLVESPGGEDSLSNTDELLGTDGDVDDDKGEVTKMETSEKNCSPSD 361
E+ + ++EE+ E+ E + +E + + ++++ E E +E+ +
Sbjct: 120 EEEAEEAEAEEEEAEEEEAEEEEAEEAEEEEAEEAEEEAEEEEAEEEAEEEAEEAEEAEE 179
Query: 362 GRHEVNEVDDDGMEEENHGPEDVEEDEE-EDGEGENEEEIEMNRVKRRMDETLRHGGTLA 420
E E ++ E E E E +EE E+ E E EE E + +E
Sbjct: 180 EAEEEAEEAEEAEEAEEAEEEAEEAEEEAEEAEEEAEEAEEAEEAEEAEEEAEE---AEE 236
Query: 421 EESEVGDTAALHDEYK------NTQQEGQAAV---VQQQKKHKEPQDKHQKAKLLESLCS 471
EE E G + YK +TQ G + +Q Q + + P+ K K+ + +
Sbjct: 237 EEEEAGPSTPRLPHYKVVGQKPSTQPGGVPKLCLKMQPQHRSRLPKGKQSHDKVPKKYQA 296
Query: 472 ENPMLSSLCGTLFPKNSQS 490
N S ++ + +S
Sbjct: 297 RNKFFSQAAPSVLDLSPKS 315
>BA2B_HUMAN (Q9UIF8) Bromodomain adjacent to zinc finger domain 2B
(hWALp4)
Length = 1972
Score = 52.0 bits (123), Expect = 4e-06
Identities = 34/105 (32%), Positives = 51/105 (48%), Gaps = 3/105 (2%)
Query: 190 RYNKHELDTSLMIIRKVMKMDAAEPFNVPVNPEALGIPDYFDIIDTPMDFGTICSNLEKN 249
R + +L MI+ ++ + A PF +PVN + +P Y +I PMDF TI L
Sbjct: 1864 RDDSKDLALCSMILTEMETHEDAWPFLLPVNLKL--VPGYKKVIKKPMDFSTIREKLSSG 1921
Query: 250 DKYMNSEDVYNDVRYIWENCYKYNNKGDYIVDLMKRVKKNFMKYW 294
+Y N E DVR +++NC +N I ++K F K W
Sbjct: 1922 -QYPNLETFALDVRLVFDNCETFNEDDSDIGRAGHNMRKYFEKKW 1965
Score = 40.4 bits (93), Expect = 0.011
Identities = 28/114 (24%), Positives = 46/114 (39%), Gaps = 18/114 (15%)
Query: 304 PKGSTDFKQEESMLVESPGGEDSLSNT-----------------DELLGTDGDVDDDKGE 346
P T S ++ S G E ++SN ++ GTD D+ K
Sbjct: 349 PGNQTPVMPSASPILHSQGKEKAVSNNVNPVKTQHHSHPAKSLVEQFRGTDSDIPSSKDS 408
Query: 347 VTKMETSEKNCSPSDGR-HEVNEVDDDGMEEENHGPEDVEEDEEEDGEGENEEE 399
E E++ D E +E DD E +++ D E EEED + ++++E
Sbjct: 409 EDSNEDEEEDDEEEDEEDDEDDESDDSQSESDSNSESDTEGSEEEDDDDKDQDE 462
Score = 37.4 bits (85), Expect = 0.090
Identities = 33/121 (27%), Positives = 52/121 (42%), Gaps = 22/121 (18%)
Query: 341 DDDKGEVTKMETSEKNCSPSDGRHEVNEVDDDGMEEENHGPEDVEEDEEEDGEGENEEEI 400
D D G T +TS + S SD DD E+E + +EE E++D + E+E +
Sbjct: 50 DSDSG--TSSDTSSEGISSSDS--------DDLEEDEEEEDQSIEESEDDDSDSESEAQH 99
Query: 401 EMNRVKRRMDETLRHGGTLAEESEVGDTAALHDEYKNTQQEGQAAVVQQ----QKKHKEP 456
+ N ++ L HG +++ G A + K Q A Q Q + K+P
Sbjct: 100 KSN------NQVLLHG--ISDPKADGQKATEKAQEKRIHQPLPLASESQTHSFQSQQKQP 151
Query: 457 Q 457
Q
Sbjct: 152 Q 152
Score = 35.4 bits (80), Expect = 0.34
Identities = 35/131 (26%), Positives = 55/131 (41%), Gaps = 21/131 (16%)
Query: 382 EDVEEDEEEDGEGENEEEIEMNRVKRRMDETLRHGGTLAEESEVGDTAALHDEYKNTQQE 441
ED EDEEED E E+EE+ E + E+ + + E SE D + ++ E
Sbjct: 409 EDSNEDEEEDDEEEDEEDDEDDESDDSQSESDSNSESDTEGSEEEDDDDKDQDESDSDTE 468
Query: 442 GQAAVVQQQKK-------------HKEPQDKH---QKAKLLESLCSENPMLSSLCGTLFP 485
G+ ++ K H P++ H +LCSE+ + L GT
Sbjct: 469 GEKTSMKLNKTTSSVKSPSMSLTGHSTPRNLHIAKAPGSAPAALCSESQSPAFL-GT--- 524
Query: 486 KNSQSVWSGPH 496
+S ++ S PH
Sbjct: 525 -SSSTLTSSPH 534
Score = 32.7 bits (73), Expect = 2.2
Identities = 25/86 (29%), Positives = 43/86 (49%), Gaps = 10/86 (11%)
Query: 310 FKQEESMLVESPGGEDSLSNTDELLGTDGDVDDDKGEVTKMETSEKNCSPSDGRHEVNEV 369
F+ +S + S EDS + +E + + DD+ E S+ + S SD +E
Sbjct: 395 FRGTDSDIPSSKDSEDSNEDEEEDDEEEDEEDDEDDE------SDDSQSESDSN---SES 445
Query: 370 DDDGMEEENHGPEDVEEDEEEDGEGE 395
D +G EEE+ +D +++ + D EGE
Sbjct: 446 DTEGSEEEDDDDKD-QDESDSDTEGE 470
Score = 32.3 bits (72), Expect = 2.9
Identities = 30/109 (27%), Positives = 44/109 (39%), Gaps = 9/109 (8%)
Query: 5 RGHKKGRPKGNTNPVSVTLTNEQEEEEEEEEETSAFDVGSKEDNNSGMEVDTPSSTGTDQ 64
RG P + S E +EEE+EE++ S+ +++S E DT S D
Sbjct: 396 RGTDSDIPSSKDSEDSNEDEEEDDEEEDEEDDEDDESDDSQSESDSNSESDTEGSEEEDD 455
Query: 65 HSNLANINPDGSIRKPVGRVKVKLKTSKMLDSQPNSSDAPSQSDTDKSS 113
+ D S G KTS L+ +S +PS S T S+
Sbjct: 456 DDK----DQDESDSDTEGE-----KTSMKLNKTTSSVKSPSMSLTGHST 495
Score = 32.0 bits (71), Expect = 3.8
Identities = 18/67 (26%), Positives = 32/67 (46%), Gaps = 12/67 (17%)
Query: 335 GTDGDVDDDKGEVTKMETSEKNCSPSDGRHEVNEVDDDGMEEENHGPEDVEEDEEEDGEG 394
G D D DDD + SD + + ++ D++ E++ D+ EDE+E +
Sbjct: 1098 GGDSDYDDDDDD------------DSDDQGDEDDEDEEDKEDKKGKKTDICEDEDEGDQA 1145
Query: 395 ENEEEIE 401
+ EE+E
Sbjct: 1146 ASVEELE 1152
>BA1A_HUMAN (Q9NRL2) Bromodomain adjacent to zinc finger domain
protein 1A (ATP-utilizing chromatin assembly and
remodeling factor 1) (hACF1) (ATP-dependent chromatin
remodelling protein) (Williams syndrome transcription
factor-related chromatin remodelin
Length = 1556
Score = 52.0 bits (123), Expect = 4e-06
Identities = 57/275 (20%), Positives = 110/275 (39%), Gaps = 39/275 (14%)
Query: 26 EQEEEEEEEEETSAFDVGSKEDN----NSGMEVDTPSSTGTDQH-----SNLANINPDGS 76
+ E++ +EEEE S G + G + SS G Q S P +
Sbjct: 1247 QDEDDSQEEEEVSLPKRGRPQVRLPVKTRGKLSSSFSSRGQQQEPGRYPSRSQQSTPKTT 1306
Query: 77 IRKPVGRVKVKL--------KTSKMLDSQPNSSDAPSQSDTDKSSQQQHGLERHGVNADR 128
+ GR K+ K+ ++ S P Q+D R +A++
Sbjct: 1307 VSSKTGRSLRKINSAPPTETKSLRIASRSTRHSHGPLQADVFVELLSPRRKRRGRKSANK 1366
Query: 129 IEDSVTSFPDLKYGASYKKAGSIKIKSSKVLGLNADQTSKPLPISSEIIHPKERKMPPLN 188
++ +FP+ + A+ S + + L L ++ + K+R+ P +
Sbjct: 1367 TPENSPNFPNFRVIATKSSEQSRSVNIASKLSLQESESKRRC---------KKRQSPEPS 1417
Query: 189 P----------RYNKHELDTSLMIIRKVMKMDAAEPFNVPVNPEALGIPDYFDIIDTPMD 238
P + HEL ++ ++++ D + PF V+ + +PDY+DII P+
Sbjct: 1418 PVTLGRRSSGRQGGVHELSAFEQLVVELVRHDDSWPFLKLVSK--IQVPDYYDIIKKPIA 1475
Query: 239 FGTICSNLEKNDKYMNSEDVYNDVRYIWENCYKYN 273
I + K + + SE + +D+ ++ NC++YN
Sbjct: 1476 LNIIREKVNKCEYKLASEFI-DDIELMFSNCFEYN 1509
Database: sprot
Posted date: Nov 25, 2004 10:54 AM
Number of letters in database: 59,974,054
Number of sequences in database: 164,201
Lambda K H
0.305 0.127 0.356
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 65,968,690
Number of Sequences: 164201
Number of extensions: 3252623
Number of successful extensions: 26311
Number of sequences better than 10.0: 821
Number of HSP's better than 10.0 without gapping: 327
Number of HSP's successfully gapped in prelim test: 515
Number of HSP's that attempted gapping in prelim test: 14153
Number of HSP's gapped (non-prelim): 4896
length of query: 496
length of database: 59,974,054
effective HSP length: 114
effective length of query: 382
effective length of database: 41,255,140
effective search space: 15759463480
effective search space used: 15759463480
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 43 (21.9 bits)
S2: 68 (30.8 bits)
Medicago: description of AC140550.8