BLAST2 result
BLASTP 2.2.2 [Dec-14-2001]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= AC138130.17 + phase: 0 /pseudo
(626 letters)
Database: sprot
164,201 sequences; 59,974,054 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
ANK3_HUMAN (Q12955) Ankyrin 3 (ANK-3) (Ankyrin G) 47 2e-04
ANK2_HUMAN (Q01484) Ankyrin 2 (Brain ankyrin) (Ankyrin B) (Ankyr... 46 3e-04
LCTA_LATMA (Q9XZC0) Alpha-latrocrustotoxin (Alpha-LCT) (Crusta1) 45 6e-04
PA26_RAT (P97570) 85 kDa calcium-independent phospholipase A2 (E... 45 7e-04
PA26_MOUSE (P97819) 85 kDa calcium-independent phospholipase A2 ... 45 7e-04
BAR1_RAT (Q9QZH2) BRCA1-associated RING domain protein 1 (BARD-1) 44 0.001
ANS1_HUMAN (Q92625) Ankyrin repeat and SAM domain protein 1 44 0.001
AN28_HUMAN (O15084) Ankyrin repeat domain protein 28 (Fragment) 44 0.001
YB23_HUMAN (Q9ULJ7) Hypothetical protein KIAA1223 (Fragment) 44 0.001
V155_FOWPV (Q9J5A7) Putative ankyrin-repeat protein FPV115 43 0.002
AS13_HUMAN (Q8WXK3) Ankyrin repeat and SOCS box protein 13 (ASB-13) 43 0.002
ANK1_HUMAN (P16157) Ankyrin 1 (Erythrocyte ankyrin) (Ankyrin R) 43 0.002
TNK2_HUMAN (Q9H2K2) Tankyrase 2 (EC 2.4.2.30) (TANK2) (Tankyrase... 43 0.003
ANR6_HUMAN (Q9Y2G4) Ankyrin repeat domain protein 6 43 0.003
YB35_SCHPO (O14340) Oxysterol-binding protein homolog C2F12.05c 42 0.004
RIK4_HUMAN (P57078) Serine/threonine-protein kinase RIPK4 (EC 2.... 42 0.004
NUC2_NEUCR (Q01317) Ankyrin repeat protein nuc-2 42 0.004
ANS1_MOUSE (P59672) Ankyrin repeat and SAM domain protein 1 42 0.004
TNK1_HUMAN (O95271) Tankyrase 1 (EC 2.4.2.30) (TANK1) (Tankyrase... 41 0.008
PA26_HUMAN (O60733) 85 kDa calcium-independent phospholipase A2 ... 41 0.008
>ANK3_HUMAN (Q12955) Ankyrin 3 (ANK-3) (Ankyrin G)
Length = 4377
Score = 47.0 bits (110), Expect = 2e-04
Identities = 38/118 (32%), Positives = 57/118 (48%), Gaps = 11/118 (9%)
Query: 39 PLHLASKYGCIEMVSEIVK--LCPDMVSAENKNMETPIHEACRQENVKVLMLLLE--VNP 94
PLH+A+KYG +E+ + +++ PD A K+ TP+H A +N KV +LLL+ +P
Sbjct: 568 PLHVAAKYGKLEVANLLLQKSASPD---AAGKSGLTPLHVAAHYDNQKVALLLLDQGASP 624
Query: 95 TAACKLNPTCKSAFLVACSHGHLDLVNLLLNLSEIVGQEVAGFDQACFHVAAVRGHTE 152
AA K T +A +D+ LL V A H+AA GH +
Sbjct: 625 HAAAKNGYT---PLHIAAKKNQMDIATTLLEYG-ADANAVTRQGIASVHLAAQEGHVD 678
Score = 45.4 bits (106), Expect = 4e-04
Identities = 36/116 (31%), Positives = 60/116 (51%), Gaps = 7/116 (6%)
Query: 38 APLHLASKYGCIEMVSEIVKLCPDMVSAENKNMETPIHEACRQENVKVLMLLLE--VNPT 95
A +HLA++ G ++MVS ++ + V+ NK+ TP+H A +++ V V +L+ +
Sbjct: 666 ASVHLAAQEGHVDMVSLLLGRNAN-VNLSNKSGLTPLHLAAQEDRVNVAEVLVNQGAHVD 724
Query: 96 AACKLNPTCKSAFLVACSHGHLDLVNLLLNLSEIVGQEVAGFDQACFHVAAVRGHT 151
A K+ T V C +G++ +VN LL S V + H AA +GHT
Sbjct: 725 AQTKMGYT---PLHVGCHYGNIKIVNFLLQHSAKVNAKTKN-GYTPLHQAAQQGHT 776
Score = 41.2 bits (95), Expect = 0.008
Identities = 26/90 (28%), Positives = 53/90 (58%), Gaps = 2/90 (2%)
Query: 39 PLHLASKYGCIEMVSEIVKLCPDMVSAENKNMETPIHEACRQENVKVLMLLLEVNPTAAC 98
PLH+ YG I++V+ +++ V+A+ KN TP+H+A +Q + ++ +LL+ N +
Sbjct: 733 PLHVGCHYGNIKIVNFLLQHSAK-VNAKTKNGYTPLHQAAQQGHTHIINVLLQ-NNASPN 790
Query: 99 KLNPTCKSAFLVACSHGHLDLVNLLLNLSE 128
+L +A +A G++ +V+ L ++E
Sbjct: 791 ELTVNGNTALGIARRLGYISVVDTLKIVTE 820
Score = 41.2 bits (95), Expect = 0.008
Identities = 27/89 (30%), Positives = 46/89 (51%), Gaps = 8/89 (8%)
Query: 39 PLHLASKYGCIEMVSEIVKLCPDMVSAENKNMETPIHEACRQENVKVLMLLLEVNPTAAC 98
PLHLA++ + V+E++ V A+ K TP+H C N+K++ LL+ +
Sbjct: 700 PLHLAAQEDRVN-VAEVLVNQGAHVDAQTKMGYTPLHVGCHYGNIKIVNFLLQ----HSA 754
Query: 99 KLNPTCKSAFL---VACSHGHLDLVNLLL 124
K+N K+ + A GH ++N+LL
Sbjct: 755 KVNAKTKNGYTPLHQAAQQGHTHIINVLL 783
Score = 37.4 bits (85), Expect = 0.12
Identities = 28/89 (31%), Positives = 46/89 (51%), Gaps = 8/89 (8%)
Query: 40 LHLASKYGCIEMVSEIVKLCPDMVSAENKNMETPIHEACRQENVKVLMLLLEVNPTAACK 99
LHLASK G +E+VSE+++ + V A K T +H A +V+ +L+ T
Sbjct: 78 LHLASKEGHVEVVSELLQREAN-VDAATKKGNTALHIASLAGQAEVVKVLV----TNGAN 132
Query: 100 LNPTCKSAF---LVACSHGHLDLVNLLLN 125
+N ++ F +A HL++V LL+
Sbjct: 133 VNAQSQNGFTPLYMAAQENHLEVVKFLLD 161
Score = 37.4 bits (85), Expect = 0.12
Identities = 43/134 (32%), Positives = 62/134 (46%), Gaps = 18/134 (13%)
Query: 27 ILNQKTDDTFSA-----PLHLASKYGCIEMVSEIVKLCPD---MVSAENKNMETPIHEAC 78
+LN+ F+A PLH+ASK G M VKL D + A+ ++ TP+H
Sbjct: 254 LLNRAAAVDFTARNDITPLHVASKRGNANM----VKLLLDRGAKIDAKTRDGLTPLHCGA 309
Query: 79 RQENVKVLMLLLEVNPTAACKLNPTCK--SAFLVACSHGHLDLVNLLLNLSEIVGQEVAG 136
R + +V+ +LL+ AA L+ T S +A HL+ V LLL + +V
Sbjct: 310 RSGHEQVVEMLLD---RAAPILSKTKNGLSPLHMATQGDHLNCVQLLLQ-HNVPVDDVTN 365
Query: 137 FDQACFHVAAVRGH 150
HVAA GH
Sbjct: 366 DYLTALHVAAHCGH 379
Score = 35.8 bits (81), Expect = 0.35
Identities = 36/133 (27%), Positives = 64/133 (48%), Gaps = 28/133 (21%)
Query: 32 TDDTFSAPLHLASKYGCIEMVSEIV--KLCPDMVSAENKNMETPIHEACRQENVKVLMLL 89
T+D +A LH+A+ G ++ ++ K P+ A+ N TP+H AC++ +KV+ LL
Sbjct: 364 TNDYLTA-LHVAAHCGHYKVAKVLLDKKANPN---AKALNGFTPLHIACKKNRIKVMELL 419
Query: 90 LE----VNPTAACKLNPTCKSAFLVACSHGHLDLVNLLL------NLSEIVGQEVAGFDQ 139
L+ + L P +AF+ GH+++V+ L+ N + + G +
Sbjct: 420 LKHGASIQAVTESGLTPIHVAAFM-----GHVNIVSQLMHHGASPNTTNVRG-------E 467
Query: 140 ACFHVAAVRGHTE 152
H+AA G E
Sbjct: 468 TALHMAARSGQAE 480
Score = 33.5 bits (75), Expect = 1.7
Identities = 27/106 (25%), Positives = 54/106 (50%), Gaps = 3/106 (2%)
Query: 20 IVKEREGILNQKTDDTFSAPLHLASKYGCIEMVSEIVKLCPDMVSAENKNMETPIHEACR 79
++ +R ++ KT D + PLH ++ G ++V ++ ++S + KN +P+H A +
Sbjct: 286 LLLDRGAKIDAKTRDGLT-PLHCGARSGHEQVVEMLLDRAAPILS-KTKNGLSPLHMATQ 343
Query: 80 QENVKVLMLLLEVNPTAACKLNPTCKSAFLVACSHGHLDLVNLLLN 125
+++ + LLL+ N N +A VA GH + +LL+
Sbjct: 344 GDHLNCVQLLLQHNVPVDDVTNDYL-TALHVAAHCGHYKVAKVLLD 388
Score = 33.5 bits (75), Expect = 1.7
Identities = 25/87 (28%), Positives = 41/87 (46%), Gaps = 2/87 (2%)
Query: 39 PLHLASKYGCIEMVSEIVKLCPDMVSAENKNMETPIHEACRQENVKVLMLLLEVNPTAAC 98
PLH+A+ YG I + + ++ V +N TP+H A ++ N ++ LLL+
Sbjct: 238 PLHIAAHYGNINVATLLLNRAA-AVDFTARNDITPLHVASKRGNANMVKLLLDRGAKIDA 296
Query: 99 KLNPTCKSAFLVACSHGHLDLVNLLLN 125
K A S GH +V +LL+
Sbjct: 297 KTRDGLTPLHCGARS-GHEQVVEMLLD 322
>ANK2_HUMAN (Q01484) Ankyrin 2 (Brain ankyrin) (Ankyrin B) (Ankyrin,
nonerythroid)
Length = 3924
Score = 46.2 bits (108), Expect = 3e-04
Identities = 41/147 (27%), Positives = 70/147 (46%), Gaps = 14/147 (9%)
Query: 11 KNDMITFSSIVKEREGILNQKTDDTFSAPLHLASKYGCIEMVSEIVKLCPDMVSAENKNM 70
+ + +S++ E + T F+ PLH+A+KYG +++ +++ SA KN
Sbjct: 539 REGQVDVASVLLEAGAAHSLATKKGFT-PLHVAAKYGSLDVAKLLLQRRAAADSA-GKNG 596
Query: 71 ETPIHEACRQENVKVLMLLLE--VNPTAACKLNPTCKSAFLVACSHGHLDLVNLLLNL-- 126
TP+H A +N KV +LLLE +P A K T +A + + + LLN
Sbjct: 597 LTPLHVAAHYDNQKVALLLLEKGASPHATAKNGYT---PLHIAAKKNQMQIASTLLNYGA 653
Query: 127 -SEIVGQEVAGFDQACFHVAAVRGHTE 152
+ IV ++ H+A+ GHT+
Sbjct: 654 ETNIVTKQ----GVTPLHLASQEGHTD 676
Score = 43.5 bits (101), Expect = 0.002
Identities = 42/146 (28%), Positives = 67/146 (45%), Gaps = 9/146 (6%)
Query: 8 AIKKNDMITFSSIVKEREGILNQKTDDTFSAPLHLASKYGCIEMVSEIVKLCPDMVSAEN 67
A KKN M S+++ G PLHLAS+ G +MV+ ++ + +
Sbjct: 636 AAKKNQMQIASTLLNY--GAETNIVTKQGVTPLHLASQEGHTDMVTLLLDKGAN-IHMST 692
Query: 68 KNMETPIHEACRQENVKVLMLLLE--VNPTAACKLNPTCKSAFLVACSHGHLDLVNLLLN 125
K+ T +H A +++ V V +L + + A KL T +VAC +G++ +VN LL
Sbjct: 693 KSGLTSLHLAAQEDKVNVADILTKHGADQDAHTKLGYT---PLIVACHYGNVKMVNFLLK 749
Query: 126 LSEIVGQEVAGFDQACFHVAAVRGHT 151
V + H AA +GHT
Sbjct: 750 QGANVNAKTKN-GYTPLHQAAQQGHT 774
Score = 40.0 bits (92), Expect = 0.018
Identities = 29/94 (30%), Positives = 53/94 (55%), Gaps = 6/94 (6%)
Query: 39 PLHLASKYGCIEMVSEIVKLCPDMVSAENKNMETPIHEACRQENVKVLMLLLE--VNPTA 96
PL +A YG ++MV+ ++K + V+A+ KN TP+H+A +Q + ++ +LL+ P A
Sbjct: 731 PLIVACHYGNVKMVNFLLKQGAN-VNAKTKNGYTPLHQAAQQGHTHIINVLLQHGAKPNA 789
Query: 97 ACKLNPTCKSAFLVACSHGHLDLVNLLLNLSEIV 130
T A +A G++ +V+ L ++E V
Sbjct: 790 TTANGNT---ALAIAKRLGYISVVDTLKVVTEEV 820
Score = 38.9 bits (89), Expect = 0.041
Identities = 35/106 (33%), Positives = 48/106 (45%), Gaps = 12/106 (11%)
Query: 24 REGILNQKTDDTFSAPLHLASKYGCIEMVSEIVK--LCPDMVSAENKNMETPIHEACRQE 81
R G L PLH+AS+ G E+V +++ PD A N TP+H + R+
Sbjct: 485 RNGALVDARAREEQTPLHIASRLGKTEIVQLLLQHMAHPD---AATTNGYTPLHISAREG 541
Query: 82 NVKVLMLLLEVNPTAACKLNPTCKSAFL---VACSHGHLDLVNLLL 124
V V +LLE A + K F VA +G LD+ LLL
Sbjct: 542 QVDVASVLLE----AGAAHSLATKKGFTPLHVAAKYGSLDVAKLLL 583
Score = 36.2 bits (82), Expect = 0.27
Identities = 37/113 (32%), Positives = 52/113 (45%), Gaps = 5/113 (4%)
Query: 39 PLHLASKYGCIEMVSEIVKLCPDMVSAENKNMETPIHEACRQENVKVLMLLLEVN-PTAA 97
PLH+ASK G MV ++ + A+ ++ TP+H A R + +V+ LLLE P A
Sbjct: 269 PLHVASKRGNTNMVKLLLDR-GGQIDAKTRDGLTPLHCAARSGHDQVVELLLERGAPLLA 327
Query: 98 CKLNPTCKSAFLVACSHGHLDLVNLLLNLSEIVGQEVAGFDQACFHVAAVRGH 150
N S +A H++ V LL V + A HVAA GH
Sbjct: 328 RTKNGL--SPLHMAAQGDHVECVKHLLQHKAPVDDVTLDYLTA-LHVAAHCGH 377
Score = 35.4 bits (80), Expect = 0.45
Identities = 28/87 (32%), Positives = 47/87 (53%), Gaps = 6/87 (6%)
Query: 40 LHLASKYGCIEMVSEIVKLCPDMVSAENKNMETPIHEACRQENVKVLMLLLE--VNPTAA 97
LH+AS G E+V +VK + ++A+++N TP++ A ++ ++ V+ LLE N + A
Sbjct: 101 LHIASLAGQAEVVKVLVKEGAN-INAQSQNGFTPLYMAAQENHIDVVKYLLENGANQSTA 159
Query: 98 CKLNPTCKSAFLVACSHGHLDLVNLLL 124
+ T VA GH V +LL
Sbjct: 160 TEDGFT---PLAVALQQGHNQAVAILL 183
Score = 34.7 bits (78), Expect = 0.77
Identities = 28/94 (29%), Positives = 44/94 (46%), Gaps = 12/94 (12%)
Query: 64 SAENKNMETPIHEACRQENVKVLMLLLE----VNPTAACKLNPTCKSAFLVACSHGHLDL 119
+A N TP+H AC++ +KV+ LL++ + L P +AF+ GHL++
Sbjct: 392 NARALNGFTPLHIACKKNRIKVMELLVKYGASIQAITESGLTPIHVAAFM-----GHLNI 446
Query: 120 VNLLLNLSEIVGQEVAGF-DQACFHVAAVRGHTE 152
V LLL +V + H+AA G E
Sbjct: 447 VLLLLQNG--ASPDVTNIRGETALHMAARAGQVE 478
Score = 33.9 bits (76), Expect = 1.3
Identities = 24/87 (27%), Positives = 47/87 (53%), Gaps = 6/87 (6%)
Query: 40 LHLASKYGCIEMVSEIVKLCPDMVSAENKNMETPIHEACRQENVKVLMLLLE--VNPTAA 97
LH+A++ G +E+V +++ +V A + +TP+H A R +++ LLL+ +P AA
Sbjct: 468 LHMAARAGQVEVVRCLLRNGA-LVDARAREEQTPLHIASRLGKTEIVQLLLQHMAHPDAA 526
Query: 98 CKLNPTCKSAFLVACSHGHLDLVNLLL 124
T ++ G +D+ ++LL
Sbjct: 527 TTNGYT---PLHISAREGQVDVASVLL 550
>LCTA_LATMA (Q9XZC0) Alpha-latrocrustotoxin (Alpha-LCT) (Crusta1)
Length = 1395
Score = 45.1 bits (105), Expect = 6e-04
Identities = 39/148 (26%), Positives = 65/148 (43%), Gaps = 4/148 (2%)
Query: 8 AIKKNDMITFSSIVKEREGILNQKTDDTFSAPLHLASKYGCIEMVSEIVKLCPDMVSAEN 67
A+ +N++ +VK + + + D+ PLH AS G +E V V+A+
Sbjct: 619 AVLQNNLSAAKVLVKSNKKVKLNEMDNNGMTPLHYASMLGNLEFVKYFTSEQGIDVNAKT 678
Query: 68 KNME-TPIHEACRQENVKVLMLLLEVNPTAACKLNPTCKSAFLVACSHGHLDLVNLLLNL 126
K TP+H A + V LL+V + +A + G+ +V +LN
Sbjct: 679 KVKNWTPLHLAILFKKFDVAQSLLQVRNIDISTRADQAITPLHLAAATGNSQIVKTILNS 738
Query: 127 SEIVGQEVA-GFDQACFHVAAVRGHTES 153
+V QE A GF H+A + +TE+
Sbjct: 739 GAVVDQETANGF--TALHLAIMNPNTET 764
Score = 37.7 bits (86), Expect = 0.091
Identities = 34/128 (26%), Positives = 57/128 (43%), Gaps = 9/128 (7%)
Query: 28 LNQKTDDTFSAPLHLASKYGCIEMVSEIVKLCPDM---VSAENKNMETPIHEACRQENVK 84
+N KT+D S PLH A+ G + I +L D + AEN + PIHEA ++
Sbjct: 775 INAKTNDG-STPLHFAAALG----KTNIFQLLMDKGANIKAENLINQMPIHEAVVNGHLA 829
Query: 85 VLMLLLEVNPTAACKLNPTCKSAFLVACSHGHLDLVNLLLNLSEIVGQEVAGFDQACFHV 144
++ +L+E + + N + F +A + D+ N L + V E H+
Sbjct: 830 IVKMLIEQDSSLMNAKNMRDEYPFYLAAEKRYKDVFNYLESKGADV-NEKNNDGNTLLHL 888
Query: 145 AAVRGHTE 152
++ G E
Sbjct: 889 FSINGEVE 896
Score = 32.3 bits (72), Expect = 3.8
Identities = 15/53 (28%), Positives = 29/53 (54%)
Query: 39 PLHLASKYGCIEMVSEIVKLCPDMVSAENKNMETPIHEACRQENVKVLMLLLE 91
PL +A+ G ++V +V+ V+ NK TP+H A +++ V+ L++
Sbjct: 1095 PLFIAAMIGQYDIVKSLVEQHKIDVNTRNKEQFTPLHAAASNDHIDVVKYLIQ 1147
>PA26_RAT (P97570) 85 kDa calcium-independent phospholipase A2 (EC
3.1.1.4) (iPLA2) (CaI-PLA2) (Group VI phospholipase A2)
(GVI PLA2)
Length = 751
Score = 44.7 bits (104), Expect = 7e-04
Identities = 27/96 (28%), Positives = 47/96 (48%)
Query: 29 NQKTDDTFSAPLHLASKYGCIEMVSEIVKLCPDMVSAENKNMETPIHEACRQENVKVLML 88
N ++ PLHLA + G E++ E+V+ C + + ET H A + +N +VL L
Sbjct: 144 NSTENEEGCTPLHLACRKGDSEILVELVQYCHAQMDVTDNKGETAFHYAVQGDNPQVLQL 203
Query: 89 LLEVNPTAACKLNPTCKSAFLVACSHGHLDLVNLLL 124
L + ++N + +AC G ++V +LL
Sbjct: 204 LGKNASAGLNQVNNQGLTPLHLACQMGKQEMVRVLL 239
>PA26_MOUSE (P97819) 85 kDa calcium-independent phospholipase A2 (EC
3.1.1.4) (iPLA2) (CaI-PLA2) (Group VI phospholipase A2)
(GVI PLA2)
Length = 752
Score = 44.7 bits (104), Expect = 7e-04
Identities = 27/96 (28%), Positives = 47/96 (48%)
Query: 29 NQKTDDTFSAPLHLASKYGCIEMVSEIVKLCPDMVSAENKNMETPIHEACRQENVKVLML 88
N ++ PLHLA + G E++ E+V+ C + + ET H A + +N +VL L
Sbjct: 145 NSTENEEGCTPLHLACRKGDSEILVELVQYCHAQMDVTDNKGETAFHYAVQGDNPQVLQL 204
Query: 89 LLEVNPTAACKLNPTCKSAFLVACSHGHLDLVNLLL 124
L + ++N + +AC G ++V +LL
Sbjct: 205 LGKNASAGLNQVNNQGLTPLHLACKMGKQEMVRVLL 240
>BAR1_RAT (Q9QZH2) BRCA1-associated RING domain protein 1 (BARD-1)
Length = 768
Score = 44.3 bits (103), Expect = 0.001
Identities = 36/116 (31%), Positives = 59/116 (50%), Gaps = 10/116 (8%)
Query: 14 MITFSSIVKEREGILNQKTDDTFSAPLHLASKYGCIEMVSEIVKLCPDMVSAENKNMETP 73
M++ S VK GI +K + LH+AS G I V +++ D ++ TP
Sbjct: 396 MMSKPSTVKLSSGIPARKRNHRGETLLHIASIKGDISSVEYLLQNGNDPNVKDHAGW-TP 454
Query: 74 IHEACRQENVKVLMLLLE----VNPTAACKLNPTCKSAFLVACSHGHLDLVNLLLN 125
+HEAC ++K++ LLL+ VN T +P +A +GH+D+V +LL+
Sbjct: 455 LHEACSHGHLKIVELLLQHNALVNTTGYHNDSPLHDAA-----KNGHIDIVKVLLS 505
>ANS1_HUMAN (Q92625) Ankyrin repeat and SAM domain protein 1
Length = 1134
Score = 44.3 bits (103), Expect = 0.001
Identities = 32/103 (31%), Positives = 50/103 (48%), Gaps = 8/103 (7%)
Query: 27 ILNQKTDDT-----FSAPLHLASKYGCIEMVSEIVKLCPDMVSAENKNMETPIHEACRQE 81
+L + TD T F PL LA+ YG +E+V ++ P+++S K TP+H A R
Sbjct: 168 LLEELTDPTMRNNKFETPLDLAALYGRLEVVKMLLNAHPNLLSCNTKK-HTPLHLAARNG 226
Query: 82 NVKVLMLLLEVNPTAACKLNPTCKSAFLVACSHGHLDLVNLLL 124
+ V+ +LL+ + SA A G D+V +LL
Sbjct: 227 HKAVVQVLLDAGMDS--NYQTEMGSALHEAALFGKTDVVQILL 267
Score = 40.8 bits (94), Expect = 0.011
Identities = 36/132 (27%), Positives = 62/132 (46%), Gaps = 19/132 (14%)
Query: 28 LNQKTDDTFSAPLHLASKYGCIEMVSEIVKLCPDMVSAENKNMETPIHEACRQENVKVLM 87
+N++ +D +A LH A++YG E+V +++ D NK ETP+ A ++V+
Sbjct: 142 VNEQNNDNETA-LHCAAQYGHTEVVKVLLEELTDPTMRNNK-FETPLDLAALYGRLEVVK 199
Query: 88 LLLEVNPTAACKLNPTCKSAFLVACSHGHLDLVNLLLNLSEIVGQEVAGFDQ-------A 140
+LL +P N + +A +GH +V +LL+ AG D +
Sbjct: 200 MLLNAHPN-LLSCNTKKHTPLHLAARNGHKAVVQVLLD---------AGMDSNYQTEMGS 249
Query: 141 CFHVAAVRGHTE 152
H AA+ G T+
Sbjct: 250 ALHEAALFGKTD 261
Score = 37.7 bits (86), Expect = 0.091
Identities = 28/91 (30%), Positives = 51/91 (55%), Gaps = 12/91 (13%)
Query: 284 VAIRTKVDINTRNNEGLTALDILDQAMDNAENRQLQAIFIRD--GGKRSTPSSFSLELDN 341
+ + D+N ++N GLTALD + + + + +++Q+ A+ I D GKRST E+D
Sbjct: 265 ILLAAGTDVNIKDNHGLTALDTV-RELPSQKSQQIAAL-IEDHMTGKRSTK-----EVDK 317
Query: 342 TSSPSP---TSRHSLSRRYISKEMEVLTEMV 369
T P P +S S+S++ + +TE++
Sbjct: 318 TPPPQPPLISSMDSISQKSQGDVEKAVTELI 348
>AN28_HUMAN (O15084) Ankyrin repeat domain protein 28 (Fragment)
Length = 1059
Score = 44.3 bits (103), Expect = 0.001
Identities = 35/127 (27%), Positives = 58/127 (45%), Gaps = 6/127 (4%)
Query: 30 QKTDDTFSAPLHLA---SKYGCIEMVSEIVKLCPDMVSAENKNMETPIHEACRQENVKVL 86
QKT+ +PLH A G EM+ I L +V+A + TP+H A ++V+ L
Sbjct: 788 QKTEGNAFSPLHCAVINDNEGAAEML--IDTLGASIVNATDSKGRTPLHAAAFTDHVECL 845
Query: 87 MLLLEVNPTAACKLNPTCKSAFLVACSHGHLDLVNLLLNLSEIVGQEVAGFDQACFHVAA 146
LLL N ++ T K+ ++A +G + V +L++ + H+A
Sbjct: 846 QLLLSHN-AQVNSVDSTGKTPLMMAAENGQTNTVEMLVSSASAELTLQDNSKNTALHLAC 904
Query: 147 VRGHTES 153
+GH S
Sbjct: 905 SKGHETS 911
Score = 42.0 bits (97), Expect = 0.005
Identities = 40/127 (31%), Positives = 59/127 (45%), Gaps = 17/127 (13%)
Query: 33 DDTFSAPLHLASKYGCIEMVSEIVKLCPDMVSAENKNMETPIHEACRQENVK----VLML 88
D + PLH A E V ++K D V+A +KN +TP+H A + VK ++ L
Sbjct: 77 DSKWLTPLHRAVASCSEEAVQVLLKHSAD-VNARDKNWQTPLHIAAANKAVKCAEALVPL 135
Query: 89 LLEVNPTAACKLNPTCKSAFLVACSHGHLDLVNLLLNLSEIVGQEVAGF---DQACFHVA 145
L VN + + ++A A GH ++V LLL+ G + F D+ H A
Sbjct: 136 LSNVNVS-----DRAGRTALHHAAFSGHGEMVKLLLSR----GANINAFDKKDRRAIHWA 186
Query: 146 AVRGHTE 152
A GH E
Sbjct: 187 AYMGHIE 193
Score = 37.0 bits (84), Expect = 0.16
Identities = 32/111 (28%), Positives = 53/111 (46%), Gaps = 3/111 (2%)
Query: 40 LHLASKYGCIEMVSEIVKLCPDMVSAENKNMETPIHEACRQENVKVLMLLLEVNPTAACK 99
+H A+ G IE+V +V + V+ ++K TP+H A + V+ LL++ +
Sbjct: 183 IHWAAYMGHIEVVKLLVSHGAE-VTCKDKKSYTPLHAAASSGMISVVKYLLDLG-VDMNE 240
Query: 100 LNPTCKSAFLVACSHGHLDLVNLLLNLSEIVGQE-VAGFDQACFHVAAVRG 149
N + VAC +G +VN L++ IV Q+ GF F A+ G
Sbjct: 241 PNAYGNTPLHVACYNGQDVVVNELIDCGAIVNQKNEKGFTPLHFAAASTHG 291
Score = 35.4 bits (80), Expect = 0.45
Identities = 31/116 (26%), Positives = 52/116 (44%), Gaps = 3/116 (2%)
Query: 39 PLHLASKYGCIEMVSEIVKLCPDMVSAENKNMETPIHEACRQENVKVLMLLL-EVNPTAA 97
PL LA+ G +E V ++ ++ + TPIH A + + L LL+ P A
Sbjct: 592 PLDLAAFKGHVECVDVLINQGASILVKDYILKRTPIHAAATNGHSECLRLLIGNAEPQNA 651
Query: 98 CKL-NPTCKSAFLVACSHGHLDLVNLLLNLSEIVGQEVAGFDQACFHVAAVRGHTE 152
+ + ++ +++ +GH D V LLN V + + + H AV GH E
Sbjct: 652 VDIQDGNGQTPLMLSVLNGHTDCVYSLLNKGANVDAK-DKWGRTALHRGAVTGHEE 706
Score = 32.3 bits (72), Expect = 3.8
Identities = 33/125 (26%), Positives = 52/125 (41%), Gaps = 4/125 (3%)
Query: 28 LNQKTDDTFSAPLHLASKYGCIEMVSEIVKLCPDMVSAENKNMETPIHEACRQENVKVLM 87
+N K+ D PLH+ + +G I++ ++ E+KN TP+H A R + ++
Sbjct: 305 VNMKSKDG-KTPLHMTALHGRFSRSQTIIQ-SGAVIDCEDKNGNTPLHIAARYGHELLIN 362
Query: 88 LLLEVNPTAACKLNPTCKSAFLVACSHGHLDLVNLLLNLSEIVGQEVAGFDQACFHVAAV 147
L+ A + L A S G D LL+ S F + C H AA
Sbjct: 363 TLITSGADTAKRGIHGMFPLHLAALS-GFSDCCRKLLS-SGFDIDTPDDFGRTCLHAAAA 420
Query: 148 RGHTE 152
G+ E
Sbjct: 421 GGNLE 425
Score = 32.0 bits (71), Expect = 5.0
Identities = 33/115 (28%), Positives = 51/115 (43%), Gaps = 10/115 (8%)
Query: 39 PLHLASKYGCIEMVSEIVKLCPDMVSAENKNMETPIHEACRQENVKVLMLLLE----VNP 94
PLH A+ G I +V ++ L DM + N TP+H AC V+ L++ VN
Sbjct: 215 PLHAAASSGMISVVKYLLDLGVDM-NEPNAYGNTPLHVACYNGQDVVVNELIDCGAIVNQ 273
Query: 95 TAACKLNPTCKSAFLVACSHGHLDLVNLLLNLSEIVGQEVAGFDQACFHVAAVRG 149
P F A +HG L L L+ N +++ + G + H+ A+ G
Sbjct: 274 KNEKGFTPL---HFAAASTHGALCLELLVGNGADVNMKSKDG--KTPLHMTALHG 323
>YB23_HUMAN (Q9ULJ7) Hypothetical protein KIAA1223 (Fragment)
Length = 768
Score = 43.9 bits (102), Expect = 0.001
Identities = 33/116 (28%), Positives = 57/116 (48%), Gaps = 9/116 (7%)
Query: 40 LHLASKYGCIEMVSEIVKLCPDMVSAENKNMETPIHEACRQENVKVLMLLLEVNPTAACK 99
LH++ G +EMV ++ D+ +A+N+ + + A Q +VKV+ LL+E
Sbjct: 322 LHVSCWQGHMEMVQVLIAYHADVNAADNEK-RSALQSAAWQGHVKVVQLLIEHGAV---- 376
Query: 100 LNPTCK---SAFLVACSHGHLDLVNLLLNLSEIVGQEVAGFDQACFHVAAVRGHTE 152
++ TC +A +A GH+D+V +LL F + VAA GH++
Sbjct: 377 VDHTCNQGATALCIAAQEGHIDVVQVLLE-HGADPNHADQFGRTAMRVAAKNGHSQ 431
>V155_FOWPV (Q9J5A7) Putative ankyrin-repeat protein FPV115
Length = 542
Score = 43.1 bits (100), Expect = 0.002
Identities = 27/97 (27%), Positives = 49/97 (49%), Gaps = 4/97 (4%)
Query: 28 LNQKTDDTFSAPLHLASKYGCIEMVSEIVKLCPDMVSAENKNMETPIHEACRQENVKVLM 87
+N K +A + + CIE V EI+K D ++ +++ TP+H AC+ ++K+
Sbjct: 245 INTKDKKGKTALHYACNSINCIETVKEIMKYGAD-INVKDREGLTPLHSACKYGDLKLSK 303
Query: 88 LLLEVNPTAACKLNPTCKSAFLVACSHGHLDLVNLLL 124
LL+E K T + +A G+++LV L+
Sbjct: 304 LLIEYGADVKVK---TTSTVLNLAVESGNVELVKFLI 337
Score = 34.3 bits (77), Expect = 1.0
Identities = 22/74 (29%), Positives = 38/74 (50%), Gaps = 13/74 (17%)
Query: 21 VKEREGILNQKTDDTFSAPLHLASKYGCIEMVSEIVKLCPDMVSAENKNMETPIHEACRQ 80
VK+REG+ PLH A KYG +++ +++ D+ + K T ++ A
Sbjct: 281 VKDREGL----------TPLHSACKYGDLKLSKLLIEYGADV---KVKTTSTVLNLAVES 327
Query: 81 ENVKVLMLLLEVNP 94
NV+++ L+E NP
Sbjct: 328 GNVELVKFLIEKNP 341
>AS13_HUMAN (Q8WXK3) Ankyrin repeat and SOCS box protein 13 (ASB-13)
Length = 278
Score = 43.1 bits (100), Expect = 0.002
Identities = 39/148 (26%), Positives = 69/148 (46%), Gaps = 10/148 (6%)
Query: 7 DAIKKNDMITFSSIVKEREGILNQKTDDTFSAPLHLASKYGCIEMVSEIVKLCPDMVSAE 66
+A ++ + + ++ E +NQ T D+ + PLH AS G V +++ V A
Sbjct: 25 EAAQRGESLQLQQLI-ESGACVNQVTVDSIT-PLHAASLQGQARCV-QLLLAAGAQVDAR 81
Query: 67 NKNMETPIHEACRQENVKVLMLLLEVNPTAACKLNPTCKSAFLV--ACSHGHLDLVNLLL 124
N + TP+ +AC +++ + LLL + K+NP +A + AC G + V LL+
Sbjct: 82 NIDGSTPLCDACASGSIECVKLLL----SYGAKVNPPLYTASPLHEACMSGSSECVRLLI 137
Query: 125 NLSEIVGQEVAGFDQACFHVAAVRGHTE 152
++ + F HVA R H +
Sbjct: 138 DVGANLEAHDCHFGTP-LHVACAREHLD 164
>ANK1_HUMAN (P16157) Ankyrin 1 (Erythrocyte ankyrin) (Ankyrin R)
Length = 1880
Score = 43.1 bits (100), Expect = 0.002
Identities = 32/88 (36%), Positives = 45/88 (50%), Gaps = 6/88 (6%)
Query: 39 PLHLASKYGCIEMVSEIVKLCPDMVSAENKNMETPIHEACRQENVKVLMLLLE--VNPTA 96
PLH+A++ G +E V +++ K TP+H A + V+V LLLE +P A
Sbjct: 505 PLHIAAREGHVETVLALLEKEASQACMTKKGF-TPLHVAAKYGKVRVAELLLERDAHPNA 563
Query: 97 ACKLNPTCKSAFLVACSHGHLDLVNLLL 124
A K T VA H +LD+V LLL
Sbjct: 564 AGKNGLT---PLHVAVHHNNLDIVKLLL 588
Score = 42.0 bits (97), Expect = 0.005
Identities = 40/152 (26%), Positives = 64/152 (41%), Gaps = 17/152 (11%)
Query: 8 AIKKNDMITFSSIVKEREGILNQKTDDTFSAPLHLASKYGCIEMVSEIVKLCPDMVSAEN 67
A KKN + ++K I ++ PLH+AS G + +V +++ + N
Sbjct: 377 ACKKNHVRVMELLLKTGASI--DAVTESGLTPLHVASFMGHLPIVKNLLQRGASP-NVSN 433
Query: 68 KNMETPIHEACRQENVKVLMLLLEVNPTAACKLNPTCKSAFLVACSHGHLDLVNLLL--- 124
+ETP+H A R + +V LL+ K ++ A GH ++V LLL
Sbjct: 434 VKVETPLHMAARAGHTEVAKYLLQNKAKVNAKAKDD-QTPLHCAARIGHTNMVKLLLENN 492
Query: 125 ---NLSEIVGQEVAGFDQACFHVAAVRGHTES 153
NL+ G H+AA GH E+
Sbjct: 493 ANPNLATTAG-------HTPLHIAAREGHVET 517
Score = 40.8 bits (94), Expect = 0.011
Identities = 26/100 (26%), Positives = 56/100 (56%), Gaps = 2/100 (2%)
Query: 24 REGILNQKTDDTFSAPLHLASKYGCIEMVSEIVKLCPDMVSAENKNMETPIHEACRQENV 83
+ G++ T PLH+AS YG I++V +++ D V+A+ K +P+H+A +Q +
Sbjct: 688 KHGVMVDATTRMGYTPLHVASHYGNIKLVKFLLQHQAD-VNAKTKLGYSPLHQAAQQGHT 746
Query: 84 KVLMLLLEVNPTAACKLNPTCKSAFLVACSHGHLDLVNLL 123
++ LLL+ N + +++ + +A G++ + ++L
Sbjct: 747 DIVTLLLK-NGASPNEVSSDGTTPLAIAKRLGYISVTDVL 785
Score = 40.8 bits (94), Expect = 0.011
Identities = 34/105 (32%), Positives = 50/105 (47%), Gaps = 9/105 (8%)
Query: 22 KEREGILNQKTDDTFSAPLHLASKYGCIEMVSEIVKLCPDMVSAENKNMETPIHEACRQE 81
K+ G L K+ T PLHL ++ G + + ++K MV A + TP+H A
Sbjct: 656 KQANGNLGNKSGLT---PLHLVAQEGHVPVADVLIKHGV-MVDATTRMGYTPLHVASHYG 711
Query: 82 NVKVLMLLLE--VNPTAACKLNPTCKSAFLVACSHGHLDLVNLLL 124
N+K++ LL+ + A KL S A GH D+V LLL
Sbjct: 712 NIKLVKFLLQHQADVNAKTKLG---YSPLHQAAQQGHTDIVTLLL 753
Score = 39.3 bits (90), Expect = 0.031
Identities = 34/117 (29%), Positives = 52/117 (44%), Gaps = 9/117 (7%)
Query: 39 PLHLASKYGCIEMVSEIVKLCPDMVSAENKNMETPIHEACRQENVKVLMLLLEVNPTAAC 98
PLH+A+KYG + V+E++ +A KN TP+H A N+ ++ LLL P
Sbjct: 538 PLHVAAKYGKVR-VAELLLERDAHPNAAGKNGLTPLHVAVHHNNLDIVKLLL---PRGGS 593
Query: 99 KLNPTCK--SAFLVACSHGHLDLVNLLLNLSEIVGQE-VAGFDQACFHVAAVRGHTE 152
+P + +A +++ LL E V G H+AA GH E
Sbjct: 594 PHSPAWNGYTPLHIAAKQNQVEVARSLLQYGGSANAESVQGVTP--LHLAAQEGHAE 648
Score = 38.5 bits (88), Expect = 0.053
Identities = 36/122 (29%), Positives = 57/122 (46%), Gaps = 19/122 (15%)
Query: 39 PLHLASKYGCIEMVSEIVKLCPDMVSAENK---NMETPIHEACRQENVKVLMLLLE---- 91
PLH+A+ G + K+ D + N N TP+H AC++ +V+V+ LLL+
Sbjct: 340 PLHVAAHCGH----HRVAKVLLDKGAKPNSRALNGFTPLHIACKKNHVRVMELLLKTGAS 395
Query: 92 VNPTAACKLNPTCKSAFLVACSHGHLDLVNLLLNLSEIVGQEVAGFD-QACFHVAAVRGH 150
++ L P ++F+ GHL +V LL V+ + H+AA GH
Sbjct: 396 IDAVTESGLTPLHVASFM-----GHLPIVKNLLQRG--ASPNVSNVKVETPLHMAARAGH 448
Query: 151 TE 152
TE
Sbjct: 449 TE 450
Score = 37.4 bits (85), Expect = 0.12
Identities = 34/117 (29%), Positives = 62/117 (52%), Gaps = 9/117 (7%)
Query: 39 PLHLASKYGCIEMVSEIVKLCPDMVSAENKNMETPIHEACRQENVKVLMLLLE--VNPTA 96
PLHLA++ G EMV+ ++ + + NK+ TP+H ++ +V V +L++ V A
Sbjct: 637 PLHLAAQEGHAEMVALLLSKQAN-GNLGNKSGLTPLHLVAQEGHVPVADVLIKHGVMVDA 695
Query: 97 ACKLNPTCKSAFLVACSHGHLDLVNLLL-NLSEIVGQEVAGFDQACFHVAAVRGHTE 152
++ T VA +G++ LV LL + +++ + G+ H AA +GHT+
Sbjct: 696 TTRMGYT---PLHVASHYGNIKLVKFLLQHQADVNAKTKLGYSP--LHQAAQQGHTD 747
Score = 36.6 bits (83), Expect = 0.20
Identities = 28/99 (28%), Positives = 49/99 (49%), Gaps = 7/99 (7%)
Query: 28 LNQKTDDTFSAPLHLASKYGCIEMVSEIVK--LCPDMVSAENKNMETPIHEACRQENVKV 85
+N K D PLH A++ G MV +++ P++ + TP+H A R+ +V+
Sbjct: 462 VNAKAKDD-QTPLHCAARIGHTNMVKLLLENNANPNLATTAG---HTPLHIAAREGHVET 517
Query: 86 LMLLLEVNPTAACKLNPTCKSAFLVACSHGHLDLVNLLL 124
++ LLE + AC + + VA +G + + LLL
Sbjct: 518 VLALLEKEASQAC-MTKKGFTPLHVAAKYGKVRVAELLL 555
Score = 34.7 bits (78), Expect = 0.77
Identities = 36/136 (26%), Positives = 65/136 (47%), Gaps = 14/136 (10%)
Query: 20 IVKEREGILNQKTDDTFSAPLHLASKYGCIEMVSEIVKLCPDMVSAENKNMETPIHEACR 79
++ +R + KT D + PLH A++ G + +SEI+ + A+ KN +PIH A +
Sbjct: 256 LLLDRGAQIETKTKDELT-PLHCAARNGHVR-ISEILLDHGAPIQAKTKNGLSPIHMAAQ 313
Query: 80 QENVKVLMLLL----EVNPTAACKLNPTCKSAFLVACSHGHLDLVNLLLNL-SEIVGQEV 134
+++ + LLL E++ L P VA GH + +LL+ ++ + +
Sbjct: 314 GDHLDCVRLLLQYDAEIDDITLDHLTP-----LHVAAHCGHHRVAKVLLDKGAKPNSRAL 368
Query: 135 AGFDQACFHVAAVRGH 150
GF H+A + H
Sbjct: 369 NGFTP--LHIACKKNH 382
Score = 31.2 bits (69), Expect = 8.5
Identities = 21/86 (24%), Positives = 42/86 (48%), Gaps = 2/86 (2%)
Query: 39 PLHLASKYGCIEMVSEIVKLCPDMVSAENKNMETPIHEACRQENVKVLMLLLEVNPTAAC 98
PLH+A+K +E+ +++ +AE+ TP+H A ++ + +++ LLL
Sbjct: 604 PLHIAAKQNQVEVARSLLQY-GGSANAESVQGVTPLHLAAQEGHAEMVALLLSKQANGNL 662
Query: 99 KLNPTCKSAFLVACSHGHLDLVNLLL 124
LVA GH+ + ++L+
Sbjct: 663 GNKSGLTPLHLVA-QEGHVPVADVLI 687
>TNK2_HUMAN (Q9H2K2) Tankyrase 2 (EC 2.4.2.30) (TANK2) (Tankyrase
II) (TNKS-2) (TRF1-interacting ankyrin-related
ADP-ribose polymerase 2) (Tankyrase-like protein)
(Tankyrase-related protein)
Length = 1166
Score = 42.7 bits (99), Expect = 0.003
Identities = 39/126 (30%), Positives = 58/126 (45%), Gaps = 9/126 (7%)
Query: 2 DQEFFDAIKKNDMITFSSIVKEREGILNQKTDDTFSAPLHLASKYGCIEMVSEIVKLCPD 61
D DA KK + + + + + T S PLHLA+ Y +E+ +++ D
Sbjct: 646 DAALLDAAKKGCLARVKKL-SSPDNVNCRDTQGRHSTPLHLAAGYNNLEVAEYLLQHGAD 704
Query: 62 MVSAENKNMETPIHEACRQENVKVLMLLLEVNPTAACKLNPTCKSAFL---VACSHGHLD 118
V+A++K P+H A +V V LL++ N AC +N T K AF A G
Sbjct: 705 -VNAQDKGGLIPLHNAASYGHVDVAALLIKYN---AC-VNATDKWAFTPLHEAAQKGRTQ 759
Query: 119 LVNLLL 124
L LLL
Sbjct: 760 LCALLL 765
Score = 37.4 bits (85), Expect = 0.12
Identities = 32/127 (25%), Positives = 59/127 (46%), Gaps = 11/127 (8%)
Query: 2 DQEFFDAIKKNDMITFSSIVKEREGILNQKTDDTFSAPLHLASKYGCIEMVSEIVKLCPD 61
D++ +A K D+ T + + + + + S PLH A+ Y + +V +++ D
Sbjct: 493 DRQLLEAAKAGDVETVKKLCTV-QSVNCRDIEGRQSTPLHFAAGYNRVSVVEYLLQHGAD 551
Query: 62 MVSAENKNMETPIHEACRQENVKVLMLLLE----VNPTAACKLNPTCKSAFLVACSHGHL 117
V A++K P+H AC + +V LL++ VN K P ++A + G
Sbjct: 552 -VHAKDKGGLVPLHNACSYGHYEVAELLVKHGAVVNVADLWKFTPLHEAA-----AKGKY 605
Query: 118 DLVNLLL 124
++ LLL
Sbjct: 606 EICKLLL 612
Score = 37.0 bits (84), Expect = 0.16
Identities = 34/120 (28%), Positives = 54/120 (44%), Gaps = 18/120 (15%)
Query: 43 ASKYGCIEMVSEIVKLCPDMVSAENKN--METPIHEACRQENVKVLMLLLEVNPTAACKL 100
A+K GC+ V ++ PD V+ + TP+H A N++V LL+ +
Sbjct: 652 AAKKGCLARVKKLSS--PDNVNCRDTQGRHSTPLHLAAGYNNLEVAEYLLQ----HGADV 705
Query: 101 NPTCKSAFLV---ACSHGHLDLVNLLLNLSEIVGQEVAGFDQACF---HVAAVRGHTESC 154
N K + A S+GH+D+ LL+ + V D+ F H AA +G T+ C
Sbjct: 706 NAQDKGGLIPLHNAASYGHVDVAALLIKYNACVN----ATDKWAFTPLHEAAQKGRTQLC 761
Score = 35.8 bits (81), Expect = 0.35
Identities = 28/98 (28%), Positives = 51/98 (51%), Gaps = 10/98 (10%)
Query: 32 TDDTFSAPLHLASKYGCIEMVSEIVKLCPDMVSAENKNMETPIHEACRQENVKVLMLLLE 91
+D S PLHLA+ Y +++V +++ D V A++K P+H AC + +V LL++
Sbjct: 207 SDGRKSTPLHLAAGYNRVKIVQLLLQHGAD-VHAKDKGDLVPLHNACSYGHYEVTELLVK 265
Query: 92 ----VNPTAACKLNPTCKSAFLVACSHGHLDLVNLLLN 125
VN + P ++A S +++ +LLL+
Sbjct: 266 HGACVNAMDLWQFTPLHEAA-----SKNRVEVCSLLLS 298
Score = 35.4 bits (80), Expect = 0.45
Identities = 21/62 (33%), Positives = 35/62 (55%), Gaps = 1/62 (1%)
Query: 30 QKTDDTFSAPLHLASKYGCIEMVSEIVKLCPDMVSAENKNMETPIHEACRQENVKVLMLL 89
Q DD PLH A +G E+V+ +++ D + +N N TP+HEA + + V ++L
Sbjct: 85 QARDDGGLIPLHNACSFGHAEVVNLLLRHGADPNARDNWNY-TPLHEAAIKGKIDVCIVL 143
Query: 90 LE 91
L+
Sbjct: 144 LQ 145
Score = 34.3 bits (77), Expect = 1.0
Identities = 28/103 (27%), Positives = 50/103 (48%), Gaps = 4/103 (3%)
Query: 3 QEFFDAIKKNDMITFSSIVKEREGILNQKTDDTFSAPLHLASKYGCIEMVSEIVKLCPDM 62
+E F+A + D+ +V E + ++ T S PLH A+ +G ++V +++ +
Sbjct: 26 RELFEACRNGDVERVKRLVTP-EKVNSRDTAGRKSTPLHFAAGFGRKDVVEYLLQNGAN- 83
Query: 63 VSAENKNMETPIHEACRQENVKVLMLLLE--VNPTAACKLNPT 103
V A + P+H AC + +V+ LLL +P A N T
Sbjct: 84 VQARDDGGLIPLHNACSFGHAEVVNLLLRHGADPNARDNWNYT 126
Score = 32.7 bits (73), Expect = 2.9
Identities = 30/77 (38%), Positives = 39/77 (49%), Gaps = 10/77 (12%)
Query: 39 PLHLASKYGCIEMVSEIVK--LCPDMVSAENKNMETPIHEACRQENVKVLMLLLE--VNP 94
PLH A YG E+ +VK C V+A + TP+HEA + V+V LLL +P
Sbjct: 247 PLHNACSYGHYEVTELLVKHGAC---VNAMDLWQFTPLHEAASKNRVEVCSLLLSYGADP 303
Query: 95 TAACKLNPTCKSAFLVA 111
T LN KSA +A
Sbjct: 304 TL---LNCHNKSAIDLA 317
Score = 31.2 bits (69), Expect = 8.5
Identities = 34/121 (28%), Positives = 52/121 (42%), Gaps = 20/121 (16%)
Query: 43 ASKYGCIEMVSEIVKL----CPDMVSAENKNMETPIHEACRQENVKVLMLLLEVNPTAAC 98
A+K G +E V ++ + C D+ ++ TP+H A V V+ LL+
Sbjct: 499 AAKAGDVETVKKLCTVQSVNCRDIEGRQS----TPLHFAAGYNRVSVVEYLLQHGADVHA 554
Query: 99 KLNPTCKSAFLV----ACSHGHLDLVNLLLNLSEIVGQEVAG-FDQACFHVAAVRGHTES 153
K LV ACS+GH ++ LL+ +V VA + H AA +G E
Sbjct: 555 K-----DKGGLVPLHNACSYGHYEVAELLVKHGAVV--NVADLWKFTPLHEAAAKGKYEI 607
Query: 154 C 154
C
Sbjct: 608 C 608
>ANR6_HUMAN (Q9Y2G4) Ankyrin repeat domain protein 6
Length = 692
Score = 42.7 bits (99), Expect = 0.003
Identities = 37/126 (29%), Positives = 57/126 (44%), Gaps = 3/126 (2%)
Query: 25 EGILNQKTDDTFSAPLHLASKYGCIEMVSEIVKLCPDMVSAENKNMETPIHEACRQENVK 84
EG + D + LH AS +G + +VK +++ A+NK T +H AC+ + +
Sbjct: 97 EGCALDRQDKDGNTALHEASWHGFSQSAKLLVKAGANVL-AKNKAGNTALHLACQNSHSQ 155
Query: 85 VLMLLLEVNPTAACKLNPTCKSAFLVACSHGHLDLVNLLLNLSEIVGQEVAGFDQACFHV 144
+LL A K N + VA + HL ++ LLL V ++ D A HV
Sbjct: 156 STRVLLLAGSRADLK-NNAGDTCLHVAARYNHLSIIRLLLTAFCSVHEKNQAGDTA-LHV 213
Query: 145 AAVRGH 150
AA H
Sbjct: 214 AAALNH 219
Score = 31.6 bits (70), Expect = 6.5
Identities = 29/119 (24%), Positives = 53/119 (44%), Gaps = 11/119 (9%)
Query: 39 PLHLASKYGCIEMVSEIVKLCPDMVSAENKNMETPIHEACRQENVKVLMLLLEVNPTAAC 98
PLHLA+ G + +V ++K D+ ++ +T +H A N +++ L+ C
Sbjct: 45 PLHLAANKGHLPVVQILLKAGCDL-DVQDDGDQTALHRATVVGNTEIIAALIH----EGC 99
Query: 99 KLNPTCK---SAFLVACSHGHLDLVNLLLNL-SEIVGQEVAGFDQACFHVAAVRGHTES 153
L+ K +A A HG LL+ + ++ + AG H+A H++S
Sbjct: 100 ALDRQDKDGNTALHEASWHGFSQSAKLLVKAGANVLAKNKAG--NTALHLACQNSHSQS 156
>YB35_SCHPO (O14340) Oxysterol-binding protein homolog C2F12.05c
Length = 1310
Score = 42.4 bits (98), Expect = 0.004
Identities = 32/122 (26%), Positives = 64/122 (52%), Gaps = 8/122 (6%)
Query: 4 EFFDAIKKNDMITF--SSIVKEREGILNQKTDDTFSAPLHLASKYGCIEMVSEIVKLCPD 61
E D++K+ ++ + +K+ + +L+ K+ D + L ++ + ++MV I+ +
Sbjct: 21 ELSDSLKQLQLLQAFQAGDIKQVDNLLHNKSKDECTHALFISIQCANVQMVKHILSVFDV 80
Query: 62 MVSAENKNMETPIHEAC---RQENVKVLMLLLEVNPTAACKLNPTCKSAFLVACSHGHLD 118
V+A +KN TP+H A RQ+ V+ L+L ++N +N K A+ VA S +D
Sbjct: 81 DVNAYDKNKNTPLHLAAMAGRQDIVEALLLHPDINYNL---VNANNKKAYQVATSPQLMD 137
Query: 119 LV 120
+
Sbjct: 138 FM 139
>RIK4_HUMAN (P57078) Serine/threonine-protein kinase RIPK4 (EC
2.7.1.37) (Receptor-interacting serine-threonine kinase
4) (Ankyrin repeat domain protein 3)
(PKC-delta-interacting protein kinase)
Length = 832
Score = 42.4 bits (98), Expect = 0.004
Identities = 32/115 (27%), Positives = 55/115 (47%), Gaps = 5/115 (4%)
Query: 39 PLHLASKYGCIEMVSEIVKLCPDMVSAENKNMETPIHEACRQENVKVLMLLLEVNPTAAC 98
PLHLA++ G + ++ LC D V+ + +TP+H A + LLL
Sbjct: 655 PLHLAAQRGHYRVARILIDLCSD-VNVCSLLAQTPLHVAAETGHTSTARLLLHRGAGKEA 713
Query: 99 KLNPTCKSAFLVACSHGHLDLVNLLLN-LSEIVGQEVAGFDQACFHVAAVRGHTE 152
+ +A +A +GHL V LL+ ++++ + +Q H+AA GH+E
Sbjct: 714 -MTSDGYTALHLAARNGHLATVKLLVEEKADVLAR--GPLNQTALHLAAAHGHSE 765
Score = 40.4 bits (93), Expect = 0.014
Identities = 32/114 (28%), Positives = 54/114 (47%), Gaps = 6/114 (5%)
Query: 39 PLHLASKYGCIEMVSEIVKLCPDMVSAENKNMETPIHEACRQENVKVLMLLLEV-NPTAA 97
PLH A+ G + +V + K V+A+ + TP+H A ++ + +V +L+++ +
Sbjct: 621 PLHYAAWQGHLPIVKLLAKQPGVSVNAQTLDGRTPLHLAAQRGHYRVARILIDLCSDVNV 680
Query: 98 CKLNPTCKSAFLVACSHGHLDLVNLLLNLSEIVGQEVAGFD-QACFHVAAVRGH 150
C L ++ VA GH LLL+ G+E D H+AA GH
Sbjct: 681 CSL--LAQTPLHVAAETGHTSTARLLLHRG--AGKEAMTSDGYTALHLAARNGH 730
Score = 35.8 bits (81), Expect = 0.35
Identities = 33/115 (28%), Positives = 57/115 (48%), Gaps = 5/115 (4%)
Query: 37 SAPLHLASKYGCIEMVSEIVKLCPDMVSAENKNMETPIHEACRQENVKVLMLLLEVNPTA 96
S PLH+A + + V E++ V+A++++ T +H A + + LLLE N +
Sbjct: 520 STPLHMAVERR-VRGVVELLLARKISVNAKDEDQWTALHFAAQNGDESSTRLLLEKNASV 578
Query: 97 ACKLNPTCKSAFLVACSHGHLDLVNLLLNLSEIVGQEVAGFDQ-ACFHVAAVRGH 150
+++ ++ VAC HG ++V +LL V + G D H AA +GH
Sbjct: 579 N-EVDFEGRTPMHVACQHGQENIVRILLRRG--VDVSLQGKDAWLPLHYAAWQGH 630
>NUC2_NEUCR (Q01317) Ankyrin repeat protein nuc-2
Length = 1066
Score = 42.4 bits (98), Expect = 0.004
Identities = 25/103 (24%), Positives = 55/103 (53%), Gaps = 7/103 (6%)
Query: 25 EGILNQKTDDTFSAPLHLASKYGCIEMVSEIVKLCPDMVSAENKNMETPIHEACRQENVK 84
+G+ ++TD PLH AS +G ++M+ ++ P ++ + + TP+ + + +++
Sbjct: 326 KGVDAERTDAYGRVPLHYASMHGRLDMIDALLNASPKTINLIDHDNFTPLVHSIVRNHLE 385
Query: 85 VLMLLLEVNPTAACKLNPTCKSAFL---VACSHGHLDLVNLLL 124
+ LLE + +++P + + +AC HG + +V LLL
Sbjct: 386 CVGRLLE----RSARIDPVSDTDHVPLNLACQHGSVAIVELLL 424
>ANS1_MOUSE (P59672) Ankyrin repeat and SAM domain protein 1
Length = 1150
Score = 42.4 bits (98), Expect = 0.004
Identities = 31/105 (29%), Positives = 51/105 (48%), Gaps = 8/105 (7%)
Query: 25 EGILNQKTDDT-----FSAPLHLASKYGCIEMVSEIVKLCPDMVSAENKNMETPIHEACR 79
+ +L + TD T F PL LA+ YG +E+V ++ P+++S + TP+H A R
Sbjct: 183 KALLEELTDPTMRNNKFETPLDLAALYGRLEVVKLLLGAHPNLLSCSTRK-HTPLHLAAR 241
Query: 80 QENVKVLMLLLEVNPTAACKLNPTCKSAFLVACSHGHLDLVNLLL 124
+ V+ +LL+ + SA A G D+V +LL
Sbjct: 242 NGHKAVVQVLLDAGMDS--NYQTEMGSALHEAALFGKTDVVQILL 284
Score = 32.0 bits (71), Expect = 5.0
Identities = 24/80 (30%), Positives = 46/80 (57%), Gaps = 10/80 (12%)
Query: 284 VAIRTKVDINTRNNEGLTALDILDQAMDNAENRQLQAIFIRD--GGKRS------TPSSF 335
+ + +D+N ++N GLTALD + + + + +++Q+ A+ I D GKRS T ++
Sbjct: 282 ILLAAGIDVNIKDNRGLTALDTV-RDLPSQKSQQIAAL-IEDHMTGKRSVKEVDRTSTAQ 339
Query: 336 SLELDNTSSPSPTSRHSLSR 355
L NT + +P S+ S+ +
Sbjct: 340 LPLLSNTDAIAPMSQGSMEK 359
Score = 31.6 bits (70), Expect = 6.5
Identities = 31/126 (24%), Positives = 53/126 (41%), Gaps = 28/126 (22%)
Query: 24 REGILNQKTDDTFSAPLHLASKYGCIEMVSEIVKLCPD---------------------- 61
R L D PLHLA+ G ++V +++ P
Sbjct: 97 RNDALTNVADSKGCYPLHLAAWKGDAQIVRLLIQQGPSHTRVNEQNALEIRELKKYGPFD 156
Query: 62 -MVSAENKNMETPIHEACRQENVKVLMLLLE--VNPTAACKLNPTCKSAFLVACSHGHLD 118
++A+N + ET +H A + + +V+ LLE +PT N ++ +A +G L+
Sbjct: 157 PYINAKNNDNETALHCAAQYGHTEVVKALLEELTDPTMR---NNKFETPLDLAALYGRLE 213
Query: 119 LVNLLL 124
+V LLL
Sbjct: 214 VVKLLL 219
>TNK1_HUMAN (O95271) Tankyrase 1 (EC 2.4.2.30) (TANK1) (Tankyrase I)
(TNKS-1) (TRF1-interacting ankyrin-related ADP-ribose
polymerase)
Length = 1327
Score = 41.2 bits (95), Expect = 0.008
Identities = 38/126 (30%), Positives = 56/126 (44%), Gaps = 9/126 (7%)
Query: 2 DQEFFDAIKKNDMITFSSIVKEREGILNQKTDDTFSAPLHLASKYGCIEMVSEIVKLCPD 61
D DA KK + + E I + T S PLHLA+ Y +E+ +++ D
Sbjct: 804 DAALLDAAKKGCLARVQKLCTP-ENINCRDTQGRNSTPLHLAAGYNNLEVAEYLLEHGAD 862
Query: 62 MVSAENKNMETPIHEACRQENVKVLMLLLEVNPTAACKLNPTCKSAFL---VACSHGHLD 118
V+A++K P+H A +V + LL++ N +N T K AF A G
Sbjct: 863 -VNAQDKGGLIPLHNAASYGHVDIAALLIKYNTC----VNATDKWAFTPLHEAAQKGRTQ 917
Query: 119 LVNLLL 124
L LLL
Sbjct: 918 LCALLL 923
Score = 38.9 bits (89), Expect = 0.041
Identities = 47/158 (29%), Positives = 69/158 (42%), Gaps = 23/158 (14%)
Query: 7 DAIKKN-DMITFSSIVKEREGILNQKTDDTFSAPLHLASKYGCIEMVSEIVKLC-PDMVS 64
D KKN D T +VKE + + A L A+K GC+ V KLC P+ ++
Sbjct: 775 DPTKKNRDGNTPLDLVKEGDTDIQDLLKG--DAALLDAAKKGCLARVQ---KLCTPENIN 829
Query: 65 AENKN--METPIHEACRQENVKVLMLLLEVNPTAACKLNPTCKSAFLV---ACSHGHLDL 119
+ TP+H A N++V LLE +N K + A S+GH+D+
Sbjct: 830 CRDTQGRNSTPLHLAAGYNNLEVAEYLLE----HGADVNAQDKGGLIPLHNAASYGHVDI 885
Query: 120 VNLLLNLSEIVGQEVAGFDQACF---HVAAVRGHTESC 154
LL+ + V D+ F H AA +G T+ C
Sbjct: 886 AALLIKYNTCVN----ATDKWAFTPLHEAAQKGRTQLC 919
Score = 37.0 bits (84), Expect = 0.16
Identities = 32/128 (25%), Positives = 56/128 (43%), Gaps = 11/128 (8%)
Query: 1 MDQEFFDAIKKNDMITFSSIVKEREGILNQKTDDTFSAPLHLASKYGCIEMVSEIVKLCP 60
+D +A K D+ T + + + + + S PLH A+ Y + +V ++
Sbjct: 650 VDYRLLEASKAGDLETVKQLCSS-QNVNCRDLEGRHSTPLHFAAGYNRVSVVEYLLHHGA 708
Query: 61 DMVSAENKNMETPIHEACRQENVKVLMLLL----EVNPTAACKLNPTCKSAFLVACSHGH 116
D V A++K P+H AC + +V LL+ VN K P ++A + G
Sbjct: 709 D-VHAKDKGGLVPLHNACSYGHYEVAELLVRHGASVNVADLWKFTPLHEAA-----AKGK 762
Query: 117 LDLVNLLL 124
++ LLL
Sbjct: 763 YEICKLLL 770
Score = 36.6 bits (83), Expect = 0.20
Identities = 29/98 (29%), Positives = 50/98 (50%), Gaps = 10/98 (10%)
Query: 32 TDDTFSAPLHLASKYGCIEMVSEIVKLCPDMVSAENKNMETPIHEACRQENVKVLMLLLE 91
+D S PLHLA+ Y + +V +++ D V A++K P+H AC + +V LLL+
Sbjct: 365 SDGRKSTPLHLAAGYNRVRIVQLLLQHGAD-VHAKDKGGLVPLHNACSYGHYEVTELLLK 423
Query: 92 ----VNPTAACKLNPTCKSAFLVACSHGHLDLVNLLLN 125
VN + P ++A S +++ +LLL+
Sbjct: 424 HGACVNAMDLWQFTPLHEAA-----SKNRVEVCSLLLS 456
Score = 33.9 bits (76), Expect = 1.3
Identities = 21/59 (35%), Positives = 33/59 (55%), Gaps = 1/59 (1%)
Query: 33 DDTFSAPLHLASKYGCIEMVSEIVKLCPDMVSAENKNMETPIHEACRQENVKVLMLLLE 91
DD PLH A +G E+VS ++ D + +N N TP+HEA + + V ++LL+
Sbjct: 246 DDGGLIPLHNACSFGHAEVVSLLLCQGADPNARDNWNY-TPLHEAAIKGKIDVCIVLLQ 303
Score = 31.6 bits (70), Expect = 6.5
Identities = 17/54 (31%), Positives = 32/54 (58%), Gaps = 1/54 (1%)
Query: 37 SAPLHLASKYGCIEMVSEIVKLCPDMVSAENKNMETPIHEACRQENVKVLMLLL 90
S+PLH A+ +G ++V ++++ + V A + P+H AC + +V+ LLL
Sbjct: 217 SSPLHFAAGFGRKDVVEHLLQMGAN-VHARDDGGLIPLHNACSFGHAEVVSLLL 269
>PA26_HUMAN (O60733) 85 kDa calcium-independent phospholipase A2 (EC
3.1.1.4) (iPLA2) (CaI-PLA2) (Group VI phospholipase A2)
(GVI PLA2)
Length = 806
Score = 41.2 bits (95), Expect = 0.008
Identities = 26/86 (30%), Positives = 43/86 (49%)
Query: 39 PLHLASKYGCIEMVSEIVKLCPDMVSAENKNMETPIHEACRQENVKVLMLLLEVNPTAAC 98
PLHLA + G E++ E+V+ C + + ET H A + +N +VL LL
Sbjct: 155 PLHLACRKGDGEILVELVQYCHTQMDVTDYKGETVFHYAVQGDNSQVLQLLGRNAVAGLN 214
Query: 99 KLNPTCKSAFLVACSHGHLDLVNLLL 124
++N + +AC G ++V +LL
Sbjct: 215 QVNNQGLTPLHLACQLGKQEMVRVLL 240
Database: sprot
Posted date: Nov 25, 2004 10:54 AM
Number of letters in database: 59,974,054
Number of sequences in database: 164,201
Lambda K H
0.330 0.140 0.426
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 67,972,841
Number of Sequences: 164201
Number of extensions: 2689123
Number of successful extensions: 10549
Number of sequences better than 10.0: 115
Number of HSP's better than 10.0 without gapping: 16
Number of HSP's successfully gapped in prelim test: 100
Number of HSP's that attempted gapping in prelim test: 10215
Number of HSP's gapped (non-prelim): 366
length of query: 626
length of database: 59,974,054
effective HSP length: 116
effective length of query: 510
effective length of database: 40,926,738
effective search space: 20872636380
effective search space used: 20872636380
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.9 bits)
S2: 69 (31.2 bits)
Medicago: description of AC138130.17