BLASTP 2.2.2 [Dec-14-2001]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= AC138130.14 + phase: 0 
         (330 letters)

Database: sprot 
           164,201 sequences; 59,974,054 total letters

Searching..................................................done

                                                                   Score     E
Sequences producing significant alignments:                        (bits)  Value

DFRA_CALCH (P51103) Dihydroflavonol-4-reductase (EC 1.1.1.219) (...   238  2e-62
DFRA_MAIZE (P51108) Dihydroflavonol-4-reductase (EC 1.1.1.219) (...   236  8e-62
DFRA_GERHY (P51105) Dihydroflavonol-4-reductase (EC 1.1.1.219) (...   233  6e-61
DFRA_ARATH (P51102) Dihydroflavonol-4-reductase (EC 1.1.1.219) (...   232  8e-61
DFRA_VITVI (P51110) Dihydroflavonol-4-reductase (EC 1.1.1.219) (...   232  1e-60
DFRA_DIACA (P51104) Dihydroflavonol-4-reductase (EC 1.1.1.219) (...   219  1e-56
DFRA_PETHY (P14720) Dihydroflavonol-4-reductase (EC 1.1.1.219) (...   218  2e-56
BAN_ARATH (Q9SEV0) Leucoanthocyanidin reductase (EC 1.-.-.-) (LA...   218  2e-56
DFRA_HORVU (P51106) Dihydroflavonol-4-reductase (EC 1.1.1.219) (...   218  2e-56
DFRA_LYCES (P51107) Dihydroflavonol-4-reductase (EC 1.1.1.219) (...   204  2e-52
DFRA_ANTMA (P14721) Dihydroflavonol-4-reductase (EC 1.1.1.219) (...   199  1e-50
DFRA_MEDSA (P51109) Dihydroflavonol-4-reductase (EC 1.1.1.219) (...   157  3e-38
ALD2_SPOSA (Q9UUN9) Aldehyde reductase II (EC 1.1.1.2) (ARII)         115  2e-25
GRE2_YEAST (Q12068) NADPH-dependent methylglyoxal reductase GRE2...   101  3e-21
YGD9_YEAST (P53183) Hypothetical protein YGL039W                       99  1e-20
YGP7_YEAST (P53111) Hypothetical protein YGL157W                       96  2e-19
DFRA_SYNY3 (P73212) Putative dihydroflavonol-4-reductase (EC 1.1...    72  2e-12
YA14_HAEIN (P44094) Hypothetical protein HI1014                        52  2e-06
3BHD_HORSE (O46516) 3 beta-hydroxysteroid dehydrogenase/delta 5-...    51  5e-06
3BHS_PIG (Q9N119) 3 beta-hydroxysteroid dehydrogenase/delta 5-->...    50  6e-06

>DFRA_CALCH (P51103) Dihydroflavonol-4-reductase (EC 1.1.1.219)
           (DFR) (Dihydrokaempferol 4-reductase)
          Length = 364

 Score =  238 bits (607), Expect = 2e-62
 Identities = 134/322 (41%), Positives = 194/322 (59%), Gaps = 11/322 (3%)

Query: 5   VCVTGASGFLASWLIKRLLLSGYHVIGTVRDLGKKQKVEHLWKLEGATERLKLVQADLME 64
           VCVTGA+GF+ SWL+ RLL  GY V  TVR+ G  +KV+HL +L  A   L L +ADL +
Sbjct: 9   VCVTGAAGFIGSWLVMRLLERGYIVRATVRNPGDMKKVKHLLELPKAETNLTLWKADLTQ 68

Query: 65  ENSFDNAIMGCKGVFHIASPVLNHISNDPKAEILEPAVQGTLNVLRSCRKNPALVRVVLA 124
           E SFD AI GC GVFH+A+P ++  S DP+ EI++P ++G L+++RSC K   + ++V  
Sbjct: 69  EGSFDEAIEGCHGVFHVATP-MDFESKDPENEIIKPTIEGILSIIRSCAKAKTVKKLVYT 127

Query: 125 SSSSAVRVRADFDPNIPI-DESSWSSLELC--EKLQAW-YPMSKTLAEKAAWDYCKENGI 180
           SS+  V V+   +  +P+ DES WS L+    +K+ AW Y +SKTLAEKAA +  KEN I
Sbjct: 128 SSAGTVNVQ---ETQLPVYDESHWSDLDFIYSKKMTAWMYFVSKTLAEKAAMEAAKENNI 184

Query: 181 DLVTILPSFIIGPNLPTDLCSTASDVLGLFKGETEKFQWHGRMGYVHIDDVALCHILLYE 240
           D V+I+P  ++GP +      +    L L  G    +    +  YVH+DD+  CHI LYE
Sbjct: 185 DFVSIIPPLVVGPFINPTFPPSLITALSLINGAESHYSIIKQGQYVHLDDLCECHIFLYE 244

Query: 241 NKASDGRYLCSSKIMDNDDLVGMLANRYPGFPIPKRFKKLDR--PHYELNTGKLESLGFK 298
           N  + GRY+CS +      L  M+  ++P + +P +F  +D   P    ++ KL  +GFK
Sbjct: 245 NPEAKGRYICSKQDATIHQLARMIKQKWPEYHVPTQFAGIDEELPTVSFSSKKLIDMGFK 304

Query: 299 FK-SVEEMFDDCFASFVEQGHL 319
           FK  +E+MF     S  E+G L
Sbjct: 305 FKYDLEDMFKGAIDSCKEKGFL 326


>DFRA_MAIZE (P51108) Dihydroflavonol-4-reductase (EC 1.1.1.219)
           (DFR) (Dihydrokaempferol 4-reductase)
          Length = 357

 Score =  236 bits (601), Expect = 8e-62
 Identities = 128/320 (40%), Positives = 196/320 (61%), Gaps = 10/320 (3%)

Query: 5   VCVTGASGFLASWLIKRLLLSGYHVIGTVRDLGKKQKVEHLWKLEGATERLKLVQADLME 64
           V VTGASGF+ SWL+ +LL +GY V  TVRD     K + L  L GATERL + +ADL E
Sbjct: 13  VLVTGASGFVGSWLVMKLLQAGYTVRATVRDPANVGKTKPLMDLPGATERLSIWKADLAE 72

Query: 65  ENSFDNAIMGCKGVFHIASPVLNHISNDPKAEILEPAVQGTLNVLRSCRKNPALVRVVLA 124
           E SF +AI GC GVFH+A+P ++ +S DP+ E+++P V+G ++++R+C++   + R+V  
Sbjct: 73  EGSFHDAIRGCTGVFHVATP-MDFLSKDPENEVIKPTVEGMISIMRACKEAGTVRRIVFT 131

Query: 125 SSSSAVRVRADFDPNIPIDESSWSSLELCE--KLQAW-YPMSKTLAEKAAWDYCKENGID 181
           SS+  V +     P    DE SW+ ++ C   K+  W Y +SKTLAEKAA  Y  E+G+D
Sbjct: 132 SSAGTVNLEERQRP--VYDEESWTDVDFCRRVKMTGWMYFVSKTLAEKAALAYAAEHGLD 189

Query: 182 LVTILPSFIIGPNLPTDLCSTASDVLGLFKGETEKFQWHGRMGYVHIDDVALCHILLYEN 241
           LVTI+P+ ++GP +   +  +    L L  G    +    ++  +H+DD+    I L+EN
Sbjct: 190 LVTIIPTLVVGPFISASMPPSLITALALITGNAPHYSILKQVQLIHLDDLCDAEIFLFEN 249

Query: 242 KASDGRYLCSSKIMDNDDLVGMLANRYPGFPIPKRFKKL--DRPHYELNTGKLESLG--F 297
            A+ GRY+CSS  +    L  ML +RYP + +P+RF  +  D      ++ KL+ LG  F
Sbjct: 250 PAAAGRYVCSSHDVTIHGLAAMLRDRYPEYDVPQRFPGIQDDLQPVRFSSKKLQDLGFTF 309

Query: 298 KFKSVEEMFDDCFASFVEQG 317
           ++K++E+MFD    +  E+G
Sbjct: 310 RYKTLEDMFDAAIRTCQEKG 329


>DFRA_GERHY (P51105) Dihydroflavonol-4-reductase (EC 1.1.1.219)
           (DFR) (Dihydrokaempferol 4-reductase)
          Length = 366

 Score =  233 bits (593), Expect = 6e-61
 Identities = 132/322 (40%), Positives = 195/322 (59%), Gaps = 11/322 (3%)

Query: 5   VCVTGASGFLASWLIKRLLLSGYHVIGTVRDLGKKQKVEHLWKLEGATERLKLVQADLME 64
           VCVTGA+GF+ SWL+ RLL  GY V  TVRD G  +KV+HL +L  A   LKL +ADL +
Sbjct: 9   VCVTGAAGFIGSWLVMRLLERGYVVHATVRDPGDLKKVKHLLELPKAQTNLKLWKADLTQ 68

Query: 65  ENSFDNAIMGCKGVFHIASPVLNHISNDPKAEILEPAVQGTLNVLRSCRKNPALVRVVLA 124
           E SFD AI GC GVFH+A+P ++  S DP+ EI++P ++G L+++RSC K   + ++V  
Sbjct: 69  EGSFDEAIQGCHGVFHLATP-MDFESKDPENEIIKPTIEGVLSIIRSCVKAKTVKKLVFT 127

Query: 125 SSSSAVRVRADFDPNIPI-DESSWSSLEL--CEKLQAW-YPMSKTLAEKAAWDYCKENGI 180
           SS+  V  +   +  + + DES WS L+    +K+ AW Y +SKTLAEKAAWD  K N I
Sbjct: 128 SSAGTVNGQ---EKQLHVYDESHWSDLDFIYSKKMTAWMYFVSKTLAEKAAWDATKGNNI 184

Query: 181 DLVTILPSFIIGPNLPTDLCSTASDVLGLFKGETEKFQWHGRMGYVHIDDVALCHILLYE 240
             ++I+P+ ++GP + +    +    L L  G    +    +  YVH+DD+  CHI LYE
Sbjct: 185 SFISIIPTLVVGPFITSTFPPSLVTALSLITGNEAHYSIIKQGQYVHLDDLCECHIYLYE 244

Query: 241 NKASDGRYLCSSKIMDNDDLVGMLANRYPGFPIPKRFKKLDR--PHYELNTGKLESLGFK 298
           N  + GRY+CSS       L  ++ +++P + IP +F  +D   P    ++ KL   GF+
Sbjct: 245 NPKAKGRYICSSHDATIHQLAKIIKDKWPEYYIPTKFPGIDEELPIVSFSSKKLIDTGFE 304

Query: 299 FK-SVEEMFDDCFASFVEQGHL 319
           FK ++E+MF     +  E+G L
Sbjct: 305 FKYNLEDMFKGAIDTCREKGLL 326


>DFRA_ARATH (P51102) Dihydroflavonol-4-reductase (EC 1.1.1.219)
           (DFR) (Dihydrokaempferol 4-reductase) (TRANSPARENT TESTA
           3 protein)
          Length = 382

 Score =  232 bits (592), Expect = 8e-61
 Identities = 131/321 (40%), Positives = 191/321 (58%), Gaps = 9/321 (2%)

Query: 5   VCVTGASGFLASWLIKRLLLSGYHVIGTVRDLGKKQKVEHLWKLEGATERLKLVQADLME 64
           VCVTGASGF+ SWL+ RLL  GY V  TVRD G  +KV+HL  L  A   L L +ADL E
Sbjct: 8   VCVTGASGFIGSWLVMRLLERGYFVRATVRDPGNLKKVQHLLDLPNAKTLLTLWKADLSE 67

Query: 65  ENSFDNAIMGCKGVFHIASPVLNHISNDPKAEILEPAVQGTLNVLRSCRKNPALVRVVLA 124
           E S+D+AI GC GVFH+A+P ++  S DP+ E+++P V G L ++++C K   + R V  
Sbjct: 68  EGSYDDAINGCDGVFHVATP-MDFESKDPENEVIKPTVNGMLGIMKACVKAKTVRRFVFT 126

Query: 125 SSSSAVRVRADFDPNIPIDESSWSSLE--LCEKLQAW-YPMSKTLAEKAAWDYCKENGID 181
           SS+  V V  +   N+  DE+ WS LE  + +K+  W Y +SKTLAEKAAWD+ +E G+D
Sbjct: 127 SSAGTVNVE-EHQKNV-YDENDWSDLEFIMSKKMTGWMYFVSKTLAEKAAWDFAEEKGLD 184

Query: 182 LVTILPSFIIGPNLPTDLCSTASDVLGLFKGETEKFQWHGRMGYVHIDDVALCHILLYEN 241
            ++I+P+ ++GP + T +  +    L         +    +  YVH+DD+   HI LYE 
Sbjct: 185 FISIIPTLVVGPFITTSMPPSLITALSPITRNEAHYSIIRQGQYVHLDDLCNAHIFLYEQ 244

Query: 242 KASDGRYLCSSKIMDNDDLVGMLANRYPGFPIPKRFKKLDR--PHYELNTGKLESLGFKF 299
            A+ GRY+CSS       +   L  +YP + +P  F+ +D      E ++ KL  +GF F
Sbjct: 245 AAAKGRYICSSHDATILTISKFLRPKYPEYNVPSTFEGVDENLKSIEFSSKKLTDMGFNF 304

Query: 300 K-SVEEMFDDCFASFVEQGHL 319
           K S+EEMF +   +  ++G L
Sbjct: 305 KYSLEEMFIESIETCRQKGFL 325


>DFRA_VITVI (P51110) Dihydroflavonol-4-reductase (EC 1.1.1.219)
           (DFR) (Dihydrokaempferol 4-reductase)
          Length = 337

 Score =  232 bits (591), Expect = 1e-60
 Identities = 130/309 (42%), Positives = 189/309 (61%), Gaps = 11/309 (3%)

Query: 5   VCVTGASGFLASWLIKRLLLSGYHVIGTVRDLGKKQKVEHLWKLEGATERLKLVQADLME 64
           VCVTGASGF+ SWL+ RLL     V  TVRD    +KV+HL  L  A   L L +ADL +
Sbjct: 8   VCVTGASGFIGSWLVMRLLERRLTVRATVRDPTNVKKVKHLLDLPKAETHLTLWKADLAD 67

Query: 65  ENSFDNAIMGCKGVFHIASPVLNHISNDPKAEILEPAVQGTLNVLRSCRKNPALVRVVLA 124
           E SFD AI GC GVFH+A+P ++  S DP+ E+++P ++G L +++SC     + R+V  
Sbjct: 68  EGSFDEAIKGCTGVFHVATP-MDFESKDPENEVIKPTIEGMLGIMKSCAAAKTVRRLVFT 126

Query: 125 SSSSAVRVRADFDPNIPI-DESSWSSLELC--EKLQAW-YPMSKTLAEKAAWDYCKENGI 180
           SS+  V ++   +  +P+ DES WS +E C  +K+ AW Y +SKTLAE+AAW Y KEN I
Sbjct: 127 SSAGTVNIQ---EHQLPVYDESCWSDMEFCRAKKMTAWMYFVSKTLAEQAAWKYAKENNI 183

Query: 181 DLVTILPSFIIGPNLPTDLCSTASDVLGLFKGETEKFQWHGRMGYVHIDDVALCHILLYE 240
           D +TI+P+ ++GP + + +  +    L    G    +    +  +VH+DD+   HI L+E
Sbjct: 184 DFITIIPTLVVGPFIMSSMPPSLITALSPITGNEAHYSIIRQGQFVHLDDLCNAHIYLFE 243

Query: 241 NKASDGRYLCSSKIMDNDDLVGMLANRYPGFPIPKRFKKLDRPHYEL--NTGKLESLGFK 298
           N  ++GRY+CSS      DL  ML  +YP + IP  FK +D     +  ++ KL  LGF+
Sbjct: 244 NPKAEGRYICSSHDCIILDLAKMLREKYPEYNIPTEFKGVDENLKSVCFSSKKLTDLGFE 303

Query: 299 FK-SVEEMF 306
           FK S+E+MF
Sbjct: 304 FKYSLEDMF 312


>DFRA_DIACA (P51104) Dihydroflavonol-4-reductase (EC 1.1.1.219)
           (DFR) (Dihydrokaempferol 4-reductase)
          Length = 360

 Score =  219 bits (557), Expect = 1e-56
 Identities = 134/326 (41%), Positives = 189/326 (57%), Gaps = 20/326 (6%)

Query: 5   VCVTGASGFLASWLIKRLLLSGYHVIGTVRDLGKKQKVEHLWKLEGATERLKLVQADLME 64
           VCVTGASGF+ SWLI RLL  GY V  TVRD    +KV+HL  L  A   L L +ADL E
Sbjct: 25  VCVTGASGFIGSWLIMRLLERGYTVRATVRDPDNTKKVQHLLDLPNAKTNLTLWKADLHE 84

Query: 65  ENSFDNAIMGCKGVFHIASPVLNHISNDPKAEILEPAVQGTLNVLRSCRKNPALVRVVLA 124
           E SFD A+ GC GVFHIA+P ++  S DP+ E+++P + G L++L+SC K   L RVV  
Sbjct: 85  EGSFDAAVDGCTGVFHIATP-MDFESKDPENEMIKPTINGMLDILKSCVK-AKLRRVVFT 142

Query: 125 SSSSAVRVRADFDPNIPIDESSWSSLELCE--KLQAW-YPMSKTLAEKAAWDYCKENGID 181
           SS   V V A   P    DE+ WS+L+     K+  W Y +SK LAE+AAW Y  EN ++
Sbjct: 143 SSGGTVNVEATQKP--VYDETCWSALDFIRSVKMTGWMYFVSKILAEQAAWKYAAENNLE 200

Query: 182 LVTILPSFIIG----PNLPTDLCSTASDVLGLFKGETEKFQWHGRMG-YVHIDDVALCHI 236
            ++I+P  ++G    P++P  L +  S +       TE      + G +VH+DD+ + HI
Sbjct: 201 FISIIPPLVVGPFIMPSMPPSLITALSPIT-----RTESHYTIIKQGQFVHLDDLCMSHI 255

Query: 237 LLYENKASDGRYLCSSKIMDNDDLVGMLANRYPGFPIPKRFK--KLDRPHYELNTGKLES 294
            LYEN  ++GRY+ S+      D+  ML   YP + +P +FK  K D    + ++ KL  
Sbjct: 256 FLYENPKANGRYIASACAATIYDIAKMLREEYPEYNVPTKFKDYKEDMGQVQFSSKKLTD 315

Query: 295 LGFKFK-SVEEMFDDCFASFVEQGHL 319
           LGF+FK  +++M+     S   +G L
Sbjct: 316 LGFEFKYGLKDMYTAAVESCRAKGLL 341


>DFRA_PETHY (P14720) Dihydroflavonol-4-reductase (EC 1.1.1.219)
           (DFR) (Dihydrokaempferol 4-reductase)
          Length = 380

 Score =  218 bits (555), Expect = 2e-56
 Identities = 121/308 (39%), Positives = 186/308 (60%), Gaps = 9/308 (2%)

Query: 5   VCVTGASGFLASWLIKRLLLSGYHVIGTVRDLGKKQKVEHLWKLEGATERLKLVQADLME 64
           VCVTGA+GF+ SWL+ RLL  GY+V  TVRD   K+KV+HL +L  A   L L +ADL  
Sbjct: 18  VCVTGAAGFIGSWLVMRLLERGYNVHATVRDPENKKKVKHLLELPKADTNLTLWKADLTV 77

Query: 65  ENSFDNAIMGCKGVFHIASPVLNHISNDPKAEILEPAVQGTLNVLRSCRKNPALVRVVLA 124
           E SFD AI GC+GVFH+A+P ++  S DP+ E+++P V+G L+++ SC K   + R+V  
Sbjct: 78  EGSFDEAIQGCQGVFHVATP-MDFESKDPENEVIKPTVRGMLSIIESCAKANTVKRLVFT 136

Query: 125 SSSSAVRVRADFDPNIPIDESSWSSLEL--CEKLQAW-YPMSKTLAEKAAWDYCKENGID 181
           SS+  + V+      +  D++SWS L+    +K+  W Y  SK LAEKAA +  K+  ID
Sbjct: 137 SSAGTLDVQE--QQKLFYDQTSWSDLDFIYAKKMTGWMYFASKILAEKAAMEEAKKKNID 194

Query: 182 LVTILPSFIIGPNLPTDLCSTASDVLGLFKGETEKFQWHGRMGYVHIDDVALCHILLYEN 241
            ++I+P  ++GP +      +    L L  G    +    +  YVH+DD+   HI LYE+
Sbjct: 195 FISIIPPLVVGPFITPTFPPSLITALSLITGNEAHYCIIKQGQYVHLDDLCEAHIFLYEH 254

Query: 242 KASDGRYLCSSKIMDNDDLVGMLANRYPGFPIPKRFKKLDR--PHYELNTGKLESLGFKF 299
             +DGR++CSS      D+  M+  ++P + +P  FK +D+  P    ++ KL  +GF+F
Sbjct: 255 PKADGRFICSSHHAIIYDVAKMVREKWPEYYVPTEFKGIDKDLPVVSFSSKKLTDMGFQF 314

Query: 300 K-SVEEMF 306
           K ++E+M+
Sbjct: 315 KYTLEDMY 322


>BAN_ARATH (Q9SEV0) Leucoanthocyanidin reductase (EC 1.-.-.-) (LAR)
           (BANYULS) (Anthocyanin spotted testa) (ast)
          Length = 340

 Score =  218 bits (555), Expect = 2e-56
 Identities = 124/326 (38%), Positives = 198/326 (60%), Gaps = 14/326 (4%)

Query: 4   KVCVTGASGFLASWLIKRLLLSGYHVIGTVRDLGKKQKVEHLWKLEGATERLKLVQADLM 63
           K CV G +G LAS LIK LL SGY V  TVRD   ++K+ HL KL+   + LK+ +ADL 
Sbjct: 12  KACVIGGTGNLASILIKHLLQSGYKVNTTVRDPENEKKIAHLRKLQELGD-LKIFKADLT 70

Query: 64  EENSFDNAIMGCKGVFHIASPVLNHISNDPKAEILEPAVQGTLNVLRSCRKNPALVRVVL 123
           +E+SF+++  GC+ +FH+A+P+ N  S DP+ ++++PA+QG +NVL+SC K+ ++ RV+ 
Sbjct: 71  DEDSFESSFSGCEYIFHVATPI-NFKSEDPEKDMIKPAIQGVINVLKSCLKSKSVKRVIY 129

Query: 124 ASSSSAVRVRADFDPNIPIDESSWSSLELC--EKLQAW-YPMSKTLAEKAAWDYCKENGI 180
            SS++AV +       I ++E +W+ +E    EK   W YP+SK LAEK AW++ KEN I
Sbjct: 130 TSSAAAVSINNLSGTGIVMNEENWTDVEFLTEEKPFNWGYPISKVLAEKTAWEFAKENKI 189

Query: 181 DLVTILPSFIIGPNLPTDLCSTASDVLGLFKGE-------TEKFQWHGRMGYVHIDDVAL 233
           +LVT++P+ I G +L +D  S+ S  +    G+        E  +  G + +VH+DD+A 
Sbjct: 190 NLVTVIPALIAGNSLLSDPPSSLSLSMSFITGKEMHVTGLKEMQKLSGSISFVHVDDLAR 249

Query: 234 CHILLYENKASDGRYLCSSKIMDNDDLVGMLANRYPGFPIPKRFKK-LDRPHYELNTGKL 292
            H+ L E + + GRY+C +      ++   L  RYP + +   F++ L  P   L++ KL
Sbjct: 250 AHLFLAEKETASGRYICCAYNTSVPEIADFLIQRYPKYNVLSEFEEGLSIPKLTLSSQKL 309

Query: 293 ESLGFKFK-SVEEMFDDCFASFVEQG 317
            + GF+F+  + EM+D     F  +G
Sbjct: 310 INEGFRFEYGINEMYDQMIEYFESKG 335


>DFRA_HORVU (P51106) Dihydroflavonol-4-reductase (EC 1.1.1.219)
           (DFR) (Dihydrokaempferol 4-reductase)
          Length = 354

 Score =  218 bits (554), Expect = 2e-56
 Identities = 119/319 (37%), Positives = 191/319 (59%), Gaps = 9/319 (2%)

Query: 5   VCVTGASGFLASWLIKRLLLSGYHVIGTVRDLGKKQKVEHLWKLEGATERLKLVQADLME 64
           V VTGASGF+ SWL+ +LL +GY V  TVRD    +K + L +L GA ERL + +ADL E
Sbjct: 8   VVVTGASGFVGSWLVMKLLQAGYTVRATVRDPANVEKTKPLLELPGAKERLSIWKADLSE 67

Query: 65  ENSFDNAIMGCKGVFHIASPVLNHISNDPKAEILEPAVQGTLNVLRSCRKNPALVRVVLA 124
           + SF+ AI GC GVFH+A+P ++  S DP+ E+++P V+G L+++R+C++   + R+V  
Sbjct: 68  DGSFNEAIAGCTGVFHVATP-MDFDSQDPENEVIKPTVEGMLSIMRACKEAGTVKRIVFT 126

Query: 125 SSSSAVRVRADFDPNIPIDESSWSSLELCE--KLQAW-YPMSKTLAEKAAWDYCKENGID 181
           SS+ +V +  +  P    D+ +WS ++ C   K+  W Y +SK LAEKAA +Y  ENG+D
Sbjct: 127 SSAGSVNI--EERPRPAYDQDNWSDIDYCRRVKMTGWMYFVSKALAEKAAMEYASENGLD 184

Query: 182 LVTILPSFIIGPNLPTDLCSTASDVLGLFKGETEKFQWHGRMGYVHIDDVALCHILLYEN 241
            ++I+P+ ++GP L   +  +    L L  G    +    ++  VH+DD+      L+E+
Sbjct: 185 FISIIPTLVVGPFLSAGMPPSLVTALALITGNEAHYSILKQVQLVHLDDLCDAMTFLFEH 244

Query: 242 KASDGRYLCSSKIMDNDDLVGMLANRYPGFPIPKRFKKLD--RPHYELNTGKLESLGFKF 299
             ++GRY+CSS       L  ML +R+P + IP++F  +D        ++ KL   GF F
Sbjct: 245 PEANGRYICSSHDATIHGLARMLQDRFPEYDIPQKFAGVDDNLQPIHFSSKKLLDHGFSF 304

Query: 300 K-SVEEMFDDCFASFVEQG 317
           + + E+MFD    +  ++G
Sbjct: 305 RYTTEDMFDAAIHTCRDKG 323


>DFRA_LYCES (P51107) Dihydroflavonol-4-reductase (EC 1.1.1.219)
           (DFR) (Dihydrokaempferol 4-reductase)
          Length = 379

 Score =  204 bits (519), Expect = 2e-52
 Identities = 117/308 (37%), Positives = 186/308 (59%), Gaps = 12/308 (3%)

Query: 5   VCVTGASGFLASWLIKRLLLSGYHVIGTVRDLGKKQKVEHLWKLEGATERLKLVQADLME 64
           V VTG +GF+ SWL+ RLL  GY+V  TVRD   ++KV+HL +L  A   L L +ADL  
Sbjct: 20  VWVTGGAGFIGSWLVMRLLERGYNVHATVRDPENQKKVKHLLELPKADTNLTLWKADLAV 79

Query: 65  ENSFDNAIMGCKGVFHIASPVLNHISNDPKAEILEPAVQGTLNVLRSCRKNPALVRVVLA 124
           E SFD AI GC+GVFH+A+P ++  S DP+ E+++P V+G L+++ SC K   + R+V  
Sbjct: 80  EGSFDEAIQGCQGVFHVATP-MDFESKDPENEVIKPTVRGMLSIIESCAKANTVKRLVFT 138

Query: 125 SSSSAVRVRADFDPNIPIDESSWSSLEL--CEKLQAW-YPMSKTLAEKAAWDYCKENGID 181
           SS+  + V+   D  +  DE+SWS L+    +K+  W Y +SK LAEKAA +  ++N ID
Sbjct: 139 SSAGTLDVQE--DQKLFYDETSWSDLDFIYAKKMTGWMYFVSKILAEKAAMEEARKNNID 196

Query: 182 LVTILPSFIIGPNLPTDLCSTASDVLGLFKGETEKFQWHGRMGYVHIDDVALCHILLYEN 241
            ++I+P  ++GP + +    +    L L    T  +    +  YVH+DD+   HI LYE+
Sbjct: 197 FISIIPPLVVGPFITSTFPPSLITALSLI---TAHYGIIKQGQYVHLDDLCEAHIFLYEH 253

Query: 242 KASDGRYLCSSKIMDNDDLVGMLANRYPGFPIPKRFKKLDR--PHYELNTGKLESLGFKF 299
             ++GR++CSS      D+  M+  ++P + +P  FK +D+       ++ KL  + F+F
Sbjct: 254 PKAEGRFICSSHHAIIYDVAKMVRQKWPEYYVPTEFKGIDKDLALVSFSSKKLMDIKFQF 313

Query: 300 K-SVEEMF 306
           K ++E+M+
Sbjct: 314 KHTLEDMY 321


>DFRA_ANTMA (P14721) Dihydroflavonol-4-reductase (EC 1.1.1.219)
           (DFR) (Dihydrokaempferol 4-reductase)
          Length = 446

 Score =  199 bits (505), Expect = 1e-50
 Identities = 114/319 (35%), Positives = 176/319 (54%), Gaps = 5/319 (1%)

Query: 5   VCVTGASGFLASWLIKRLLLSGYHVIGTVRDLGKKQKVEHLWKLEGATERLKLVQADLME 64
           VCVTGA+GF+ SWL+ RLL  GY V  TVRD G  +KV+HL +L  A   L L +AD+  
Sbjct: 20  VCVTGAAGFIGSWLVMRLLERGYTVRATVRDPGNMKKVKHLIELPKADTNLTLWKADMTV 79

Query: 65  ENSFDNAIMGCKGVFHIASPVLNHISNDPKAEILEPAVQGTLNVLRSCRKNPALVRVVLA 124
           E SFD AI GC+GVFH+A+  +   S DP+ E+++P + G LN+++SC +   + + +  
Sbjct: 80  EGSFDEAIQGCEGVFHLATS-MEFDSVDPENEVIKPTIDGMLNIIKSCVQAKTVKKFIFT 138

Query: 125 SSSSAVRVRADFDPNIPIDESSWSSLELCEKLQAW-YPMSKTLAEKAAWDYCKENGIDLV 183
           +S   V V     P     +SS       +K+  W Y +SK LAEKA  +  KEN ID +
Sbjct: 139 TSGGTVNVEEHQKPVYDETDSSDMDFINSKKMTGWMYFVSKILAEKAGMEAAKENNIDFI 198

Query: 184 TILPSFIIGPNLPTDLCSTASDVLGLFKGETEKFQWHGRMGYVHIDDVALCHILLYENKA 243
           +I+P  ++GP +      +    L    G    +    +  YVH+DD+   HI L+E   
Sbjct: 199 SIIPPLVVGPFIMPTFPPSLITALSPITGNEAHYSIIKQCQYVHLDDLCEGHIFLFEYPK 258

Query: 244 SDGRYLCSSKIMDNDDLVGMLANRYPGFPIPKRFKKLDR--PHYELNTGKLESLGFKFK- 300
           ++GRY+CSS      D+  ++   +P + IP  F+ +D+  P    ++ K+  +GF FK 
Sbjct: 259 AEGRYICSSHDATIYDIAKLITENWPEYHIPDEFEGIDKDIPVVSFSSKKMIGMGFIFKY 318

Query: 301 SVEEMFDDCFASFVEQGHL 319
           ++E+M      +  E+G L
Sbjct: 319 TLEDMVRGAIDTCREKGML 337


>DFRA_MEDSA (P51109) Dihydroflavonol-4-reductase (EC 1.1.1.219)
           (DFR) (Dihydrokaempferol 4-reductase) (Fragment)
          Length = 217

 Score =  157 bits (397), Expect = 3e-38
 Identities = 86/219 (39%), Positives = 131/219 (59%), Gaps = 6/219 (2%)

Query: 16  SWLIKRLLLSGYHVIGTVRDLGKKQKVEHLWKLEGATERLKLVQADLMEENSFDNAIMGC 75
           SWL+ RL+  GY V  TVRD    +KV  L +L GA  +L + +ADL EE SFD AI GC
Sbjct: 2   SWLVMRLMEPGYMVRATVRDPENLKKVSPLLELPGAKSKLSIWKADLGEEGSFDEAIKGC 61

Query: 76  KGVFHIASPVLNHISNDPKAEILEPAVQGTLNVLRSCRKNPALVRVVLASSSSAVRVRAD 135
            GVFH+A+P ++  S DP+ E+++P ++G L+++++C K   + R++  SS+  + V  D
Sbjct: 62  TGVFHVATP-MDFESKDPENEMIKPTIKGVLDIMKACLKAKTVRRLIYTSSAGTLNVTED 120

Query: 136 FDPNIPIDESSWSSLELCE--KLQAW-YPMSKTLAEKAAWDYCKENGIDLVTILPSFIIG 192
             P    DES WS +E C   K+  W Y +SKTLAE+ AW + KE+ +D++TI+P  ++G
Sbjct: 121 QKP--LWDESCWSDVEFCRRVKMTGWMYFVSKTLAEQEAWKFAKEHKMDVITIIPPLVVG 178

Query: 193 PNLPTDLCSTASDVLGLFKGETEKFQWHGRMGYVHIDDV 231
           P L   +  +    L    G    +    +  YVH+DD+
Sbjct: 179 PFLIPTMPPSLITALSPITGNEAHYSIIKQGQYVHLDDL 217


>ALD2_SPOSA (Q9UUN9) Aldehyde reductase II (EC 1.1.1.2) (ARII)
          Length = 342

 Score =  115 bits (287), Expect = 2e-25
 Identities = 101/330 (30%), Positives = 153/330 (45%), Gaps = 26/330 (7%)

Query: 5   VCVTGASGFLASWLIKRLLLSGYHVIGTVRDLGKKQKVEHLWKLEGATERLKLVQADLME 64
           V VTGA+GF+AS ++++LL  GY V GT R   K   ++  W  +        V  D+++
Sbjct: 14  VLVTGANGFVASHVVEQLLEHGYKVRGTARSASKLANLQKRWDAKYPGRFETAVVEDMLK 73

Query: 65  ENSFDNAIMGCKGVFHIASPVLNHISNDPKAEILEPAVQGTLNVLRSCRKNPALVRVVLA 124
           + ++D  I G  GV HIAS V      D   E++ PA+ GTLN LR+    P++ R VL 
Sbjct: 74  QGAYDEVIKGAAGVAHIASVVSFSNKYD---EVVTPAIGGTLNALRAAAATPSVKRFVLT 130

Query: 125 SSSSAVRVRADFDPNIPIDESSWSSLELCEKLQA----------W-YPMSKTLAEKAAWD 173
           SS+ +  +       I +DE SW +LE  +K +           W Y  SKT AE AAW 
Sbjct: 131 SSTVSALIPKPNVEGIYLDEKSW-NLESIDKAKTLPESDPQKSLWVYAASKTEAELAAWK 189

Query: 174 YCKEN--GIDLVTILPSFIIGP--NLPTDLCSTASDVLGLFKGE-TEKFQWHGRMGYVHI 228
           +  EN     L  +LP++ IG   +  T   ST+  ++ LF GE +          YV  
Sbjct: 190 FMDENKPHFTLNAVLPNYTIGTIFDPETQSGSTSGWMMSLFNGEVSPALALMPPQYYVSA 249

Query: 229 DDVALCHI-LLYENKASDGRYLCSSKIMDNDDLVGMLANRYPGFPIPKRFKKLDRPHYEL 287
            D+ L H+  L   +    R   ++   D + ++      YP    P  F    +   + 
Sbjct: 250 VDIGLLHLGCLVLPQIERRRVYGTAGTFDWNTVLATFRKLYPSKTFPADFPDQGQDLSKF 309

Query: 288 NTGK----LESLGFK-FKSVEEMFDDCFAS 312
           +T      L+SLG   ++S+EE   D   S
Sbjct: 310 DTAPSLEILKSLGRPGWRSIEESIKDLVGS 339


>GRE2_YEAST (Q12068) NADPH-dependent methylglyoxal reductase GRE2
           (EC 1.1.1.-) (Genes de respuesta a estres protein 2)
          Length = 342

 Score =  101 bits (251), Expect = 3e-21
 Identities = 97/335 (28%), Positives = 161/335 (47%), Gaps = 38/335 (11%)

Query: 5   VCVTGASGFLASWLIKRLLLSGYHVIGTVRDLGKKQKVEHLWKLEGATERLKL-VQADLM 63
           V V+GA+GF+A  ++  LL   Y VIG+ R    ++K E+L +  G   +  + V  D+ 
Sbjct: 3   VFVSGANGFIAQHIVDLLLKEDYKVIGSAR---SQEKAENLTEAFGNNPKFSMEVVPDIS 59

Query: 64  EENSFDNAIM----GCKGVFHIASPVLNHISNDPKAEILEPAVQGTLNVLRSCRKNPA-- 117
           + ++FD+         K V H ASP    I+ D + ++L PAV G   +L S +K  A  
Sbjct: 60  KLDAFDHVFQKHGKDIKIVLHTASPFCFDIT-DSERDLLIPAVNGVKGILHSIKKYAADS 118

Query: 118 LVRVVLASSSSAV-RVRADFDPNIPIDESSW--SSLELCEKLQA-WYPMSKTLAEKAAWD 173
           + RVVL SS +AV  +  + D ++  +E SW  ++ E C+      Y  SK  AEKAAW+
Sbjct: 119 VERVVLTSSYAAVFDMAKENDKSLTFNEESWNPATWESCQSDPVNAYCGSKKFAEKAAWE 178

Query: 174 YCKEN----GIDLVTILPSFIIGPNL--------PTDLCSTASDVLGLFKGETEKFQWHG 221
           + +EN      +L  + P ++ GP +            C   + ++ L   E +  +  G
Sbjct: 179 FLEENRDSVKFELTAVNPVYVFGPQMFDKDVKKHLNTSCELVNSLMHL-SPEDKIPELFG 237

Query: 222 RMGYVHIDDVALCHILLYENKASDG-RYLCSSKIMDNDDLVGMLANRYPGFP--IPKRFK 278
             GY+ + DVA  H++ ++ + + G R + S       D++ +L   +P     IP    
Sbjct: 238 --GYIDVRDVAKAHLVAFQKRETIGQRLIVSEARFTMQDVLDILNEDFPVLKGNIPVGKP 295

Query: 279 KLDRPHYEL-----NTGKLESLGFKFKSVEEMFDD 308
                H  L     N    + LGFKF++++E  DD
Sbjct: 296 GSGATHNTLGATLDNKKSKKLLGFKFRNLKETIDD 330


>YGD9_YEAST (P53183) Hypothetical protein YGL039W
          Length = 348

 Score = 99.0 bits (245), Expect = 1e-20
 Identities = 100/346 (28%), Positives = 164/346 (46%), Gaps = 45/346 (13%)

Query: 5   VCVTGASGFLASWLIKRLLLSGYHVIGTVRDLGKKQKVEHLWKLEGATERLKL-VQADLM 63
           V V+GA+GF+A  ++  LL +GY VIG+ R    ++K + L K   +   L + +  D+ 
Sbjct: 8   VFVSGATGFIALHVVDDLLKTGYKVIGSGR---SQEKNDGLLKKFKSNPNLSMEIVEDIA 64

Query: 64  EENSFDNAIM----GCKGVFHIASPVLNHISNDPKAEILEPAVQGTLNVLRSCRKNPA-- 117
             N+FD          K V HIASPV +  + D + ++L PAV GT ++L + +   A  
Sbjct: 65  APNAFDKVFQKHGKEIKVVLHIASPV-HFNTTDFEKDLLIPAVNGTKSILEAIKNYAADT 123

Query: 118 LVRVVLASSSSAVRVRADF-DPNIPIDESSWS--SLELCE-KLQAWYPMSKTLAEKAAWD 173
           + +VV+ SS +A+    D  D +  ++E SW+  + E C+    + Y  SK  AEK AWD
Sbjct: 124 VEKVVITSSVAALASPGDMKDTSFVVNEESWNKDTWESCQANAVSAYCGSKKFAEKTAWD 183

Query: 174 YCKEN----GIDLVTILPSFIIGPNLPTD-----LCSTASDVLGLFKGETEKFQWHGRMG 224
           + +EN       L TI P F+ GP L  D     + S+++ +  L   +     ++    
Sbjct: 184 FLEENQSSIKFTLSTINPGFVFGPQLFADSLRNGINSSSAIIANLVSYKLGDNFYNYSGP 243

Query: 225 YVHIDDVALCHILLYENKASDGRYL-------CSSKIMD--NDD---LVGMLANRYPGFP 272
           ++ + DV+  H+L +E     G+ L       CS + +D  N++   L G +A   PG  
Sbjct: 244 FIDVRDVSKAHLLAFEKPECAGQRLFLCEDMFCSQEALDILNEEFPQLKGKIATGEPGSG 303

Query: 273 ---IPKRFKKLDRPHYELNTGKLESLGFKFKSVEEMFDDCFASFVE 315
              + K   K D      N      LGF+F    +   D  +  +E
Sbjct: 304 STFLTKNCCKCD------NRKTKNLLGFQFNKFRDCIVDTASQLLE 343


>YGP7_YEAST (P53111) Hypothetical protein YGL157W
          Length = 347

 Score = 95.5 bits (236), Expect = 2e-19
 Identities = 99/343 (28%), Positives = 165/343 (47%), Gaps = 39/343 (11%)

Query: 5   VCVTGASGFLASWLIKRLLLSGYHVIGTVRDLGKKQKVEHLWKLEGATERLKL-VQADLM 63
           V V+GA+GF+A  ++  LL +GY VIG+ R    ++K + L K      +L + +  D+ 
Sbjct: 7   VFVSGATGFIALHIMNDLLKAGYTVIGSGR---SQEKNDGLLKKFNNNPKLSMEIVEDIA 63

Query: 64  EENSFDNAI----MGCKGVFHIASPVLNHISNDPKAEILEPAVQGTLNVLRSCRKNPA-- 117
             N+FD          K V H ASP     +N  K ++L PAV GT ++L + +K  A  
Sbjct: 64  APNAFDEVFKKHGKEIKIVLHTASPFHFETTNFEK-DLLTPAVNGTKSILEAIKKYAADT 122

Query: 118 LVRVVLASSSSAVRVRADFDP-NIPIDESSWS--SLELCE-KLQAWYPMSKTLAEKAAWD 173
           + +V++ SS++A+    D +  ++ I E SW+  + + C+    A Y  SK  AEK AW+
Sbjct: 123 VEKVIVTSSTAALVTPTDMNKGDLVITEESWNKDTWDSCQANAVAAYCGSKKFAEKTAWE 182

Query: 174 YCKEN----GIDLVTILPSFIIGPNLPTDL----CSTASDVLGLFKGETEKFQWHGRMG- 224
           + KEN       L TI P F+ GP +  D      +T+S ++          +++   G 
Sbjct: 183 FLKENKSSVKFTLSTINPGFVFGPQMFADSLKHGINTSSGIVSELIHSKVGGEFYNYCGP 242

Query: 225 YVHIDDVALCHILLYENKASDGRYL-------CSSKIMD--NDD---LVGMLANRYPGFP 272
           ++ + DV+  H++  E     G+ L       C  +I+D  N++   L G +A   P   
Sbjct: 243 FIDVRDVSKAHLVAIEKPECTGQRLVLSEGLFCCQEIVDILNEEFPQLKGKIATGEPATG 302

Query: 273 IPKRFKKLDRPHYELNTGKLESLGFKFKSVEEMFDDCFASFVE 315
            P   +K         T KL  LGF+F ++++   D  A  +E
Sbjct: 303 -PSFLEKNSCKFDNSKTKKL--LGFQFYNLKDCIVDTAAQMLE 342


>DFRA_SYNY3 (P73212) Putative dihydroflavonol-4-reductase (EC
           1.1.1.219) (DFR) (Dihydrokaempferol 4-reductase)
          Length = 343

 Score = 71.6 bits (174), Expect = 2e-12
 Identities = 80/279 (28%), Positives = 125/279 (44%), Gaps = 38/279 (13%)

Query: 7   VTGASGFLASWLIKRLLLSGYHVIGTVRDLGKKQKVEHLWKLEGATERLKLVQADLMEEN 66
           VTG +GF+ + L++ LL  GY V   VR   +   +++L         +  V  DL  + 
Sbjct: 15  VTGGTGFVGANLVRHLLEQGYQVRALVRASSRPDNLQNL--------PIDWVVGDL-NDG 65

Query: 67  SFDNAIMGCKGVFHIASPVLNHIS--NDPKAEILEPAVQGTLNVLRSCRKNPALVRVVLA 124
                + GC+G+FH+A+    H S     +  +    V GT N+L +C +   + R V  
Sbjct: 66  DLHQQMQGCQGLFHVAA----HYSLWQKDREALYRSNVLGTRNIL-ACAQKAGIERTVYT 120

Query: 125 SSSSAVRVRADFDPNIPIDESSWSSLELCEKLQAWYPMSKTLAEKAAWDYCKENGIDLVT 184
           SS +A+ V+ D       DES  S +   EKL   Y  SK  AE+ A     + G D+V 
Sbjct: 121 SSVAAIGVKGD---GQRADESYQSPV---EKLIGAYKQSKYWAEQEALT-AAQQGQDIVI 173

Query: 185 ILPSFIIGP--NLPTDLCSTASDVLGLFKGETEKFQWHGRMGYVHIDDVALCHILLYENK 242
           + PS  IGP    PT    T   +L   + +   +   G +  + + DVA  H+L ++  
Sbjct: 174 VNPSTPIGPWDIKPT---PTGEIILRFLRRQMPAYVNTG-LNLIDVRDVAAGHLLAWQRG 229

Query: 243 AS----DGRYLCSSKIMDNDDLVGMLA--NRYPGFPIPK 275
            +      RY+      +N  L G+LA  +   G P PK
Sbjct: 230 KTALTRGDRYILGH---ENISLQGILAHLSTITGLPAPK 265


>YA14_HAEIN (P44094) Hypothetical protein HI1014
          Length = 315

 Score = 52.0 bits (123), Expect = 2e-06
 Identities = 53/207 (25%), Positives = 84/207 (39%), Gaps = 30/207 (14%)

Query: 4   KVCVTGASGFLASWLIKRLLL-SGYHV-----IGTVRDLGKKQKVEHLWKLEGATERLKL 57
           KV +TG  GFL   L K LL  +  H+     I  V+ +                 R++ 
Sbjct: 2   KVVITGGQGFLGQRLAKTLLAQNNVHIDDLILIDVVKPIAPNND-----------PRVRC 50

Query: 58  VQADLMEENSFDNAIMG-CKGVFHIASPVLNHISNDPKAEILEPAVQGTLNVLRSCRKNP 116
            + +L      D  I      +FH+A+ V +H   DP     E     T N+L  CRKN 
Sbjct: 51  YEMNLRYPTGLDELITEETDAIFHLAAIVSSHAEQDPDLGY-ETNFLATRNILEICRKNN 109

Query: 117 ALVRVVLASSSSAVRVRADFDPNIPIDESSWSSLELCEKLQAWYPMSKTLAEKAAWDYCK 176
             VR +    SS++ +     P   +D ++++        Q+ Y   K + E    DY +
Sbjct: 110 PKVRFIF---SSSLAIFGGELPETILDSTAFTP-------QSTYGTQKAMCELLINDYSR 159

Query: 177 ENGID-LVTILPSFIIGPNLPTDLCST 202
           +  +D +V  LP+  I P  P    S+
Sbjct: 160 KGFVDGIVVRLPTICIRPGKPNKAASS 186


>3BHD_HORSE (O46516) 3 beta-hydroxysteroid dehydrogenase/delta
           5-->4-isomerase (3Beta-HSD) (3b-HSD) [Includes:
           3-beta-hydroxy-delta(5)-steroid dehydrogenase (EC
           1.1.1.145) (3-beta-hydroxy-5-ene steroid dehydrogenase)
           (Progesterone reductase); Steroid delt
          Length = 372

 Score = 50.8 bits (120), Expect = 5e-06
 Identities = 61/201 (30%), Positives = 94/201 (46%), Gaps = 21/201 (10%)

Query: 7   VTGASGFLASWLIKRLLLSGYHV--IGTVRDLGKKQKVEHLWKLEGATERLKLVQADLME 64
           VTGA GFL   ++ RLL+    V  I  +  + + +  E   KL+    +L +++ D+++
Sbjct: 7   VTGAGGFLGQRIV-RLLVEEKEVQEIRALDKVFRPELREEFSKLQSKV-KLTVLEGDILD 64

Query: 65  ENSFDNAIMGCKGVFHIASPVLNHISNDPKAEI-LEPAVQGTLNVLRSCRKNPALVRVVL 123
           E     A  G   V H AS +   ++N    ++ +   V+GT  +L +C +  A V + +
Sbjct: 65  EQFLKRACQGASAVIHTASII--DVTNLFNPQVTMNVNVEGTQLLLEACSQ--ASVPIFI 120

Query: 124 ASSSSAVRVRADFDPNI--PIDESSWSSLELCEKLQAWYPMSKTLAEK---AAWDYCKEN 178
            +SS AV       PN    I ++      L  K  + YP SK LAEK   AA     +N
Sbjct: 121 YTSSVAVA-----GPNSYREIIQNGHEEAHLETKWSSPYPYSKKLAEKAVLAANGLPLKN 175

Query: 179 GIDLVT--ILPSFIIGPNLPT 197
           G  L T  + P FI G   PT
Sbjct: 176 GGTLYTCALRPMFIYGEGSPT 196


>3BHS_PIG (Q9N119) 3 beta-hydroxysteroid dehydrogenase/delta
           5-->4-isomerase (3Beta-HSD) [Includes:
           3-beta-hydroxy-delta(5)-steroid dehydrogenase (EC
           1.1.1.145) (3-beta-hydroxy-5-ene steroid dehydrogenase)
           (Progesterone reductase); Steroid delta-isomerase
          Length = 372

 Score = 50.4 bits (119), Expect = 6e-06
 Identities = 64/239 (26%), Positives = 109/239 (44%), Gaps = 19/239 (7%)

Query: 7   VTGASGFLASWLIKRLLLS-GYHVIGTVRDLGKKQKVEHLWKLEGATERLKLVQADLMEE 65
           VTG  GFL   ++  LL       I  +  + K +  E   KL+    +L +++ D+++E
Sbjct: 7   VTGGGGFLGQRIVHLLLEEKDLQEIRVLDKVFKPEVREEFSKLQSKI-KLTMLEGDILDE 65

Query: 66  NSFDNAIMGCKGVFHIASPVLNHISNDPKAEILEPAVQGTLNVLRSCRKNPALVRVVLAS 125
                A  G   V H AS +++ ++   +  +++  V+GT  +L +C +  A V V + +
Sbjct: 66  QCLKGACQGASVVIHTAS-IIDVVNAVGRETVMKVNVKGTQLLLEACVQ--ASVPVFIHT 122

Query: 126 SSSAVRVRADFDPNIPIDESSWSSLELCEKLQAWYPMSKTLAEKAAWD---YCKENGIDL 182
           SS  V     +   I   +++     L     A YP+SK LAEKA  +   +  +NG  L
Sbjct: 123 SSIEVAGPNSYREVI---QNACEEDRLETAWSAPYPLSKKLAEKAVLEANGWALQNGGTL 179

Query: 183 VT--ILPSFIIGPNLPTDLC--STASDVLGLFKGETEKFQWHGRMGYVHIDDVALCHIL 237
            T  + P +I G   P      + A +  G+      KF    R+  V++ +VA  HIL
Sbjct: 180 HTCALRPMYIYGEGSPFIFAHMNKALENNGVLT-HNSKF---SRVNPVYVGNVAWAHIL 234


  Database: sprot
    Posted date:  Nov 25, 2004 10:54 AM
  Number of letters in database: 59,974,054
  Number of sequences in database:  164,201
  
Lambda     K      H
   0.321    0.138    0.422 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 40,942,270
Number of Sequences: 164201
Number of extensions: 1735885
Number of successful extensions: 4386
Number of sequences better than 10.0: 104
Number of HSP's better than 10.0 without gapping: 29
Number of HSP's successfully gapped in prelim test: 75
Number of HSP's that attempted gapping in prelim test: 4257
Number of HSP's gapped (non-prelim): 107
length of query: 330
length of database: 59,974,054
effective HSP length: 111
effective length of query: 219
effective length of database: 41,747,743
effective search space: 9142755717
effective search space used: 9142755717
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 66 (30.0 bits)