BLASTP 2.2.2 [Dec-14-2001]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= AC137831.14 + phase: 0 
         (429 letters)

Database: sprot 
           164,201 sequences; 59,974,054 total letters

Searching..................................................done

                                                                   Score     E
Sequences producing significant alignments:                        (bits)  Value

SN72_HUMAN (Q9NZZ3) SNF7 domain containing protein 2 (CGI-34) (H...    53  2e-06
SN72_MOUSE (Q9D7S9) SNF7 domain containing protein 2                   52  3e-06
M24_STRPY (P12379) M protein, serotype 24 precursor                    49  2e-05
SNF7_YEAST (P39929) Nuclear protein SNF7                               47  7e-05
CNC3_HUMAN (Q9BY43) Protein C14orf123 (HSPC134) (CDA04)                47  9e-05
GOA4_HUMAN (Q13439) Golgi autoantigen, golgin subfamily A member...    46  2e-04
M5_STRP5 (P02977) M protein, serotype 5 precursor                      44  0.001
HCR_GORGO (Q8HZ59) Alpha helical coiled-coil rod protein               42  0.002
TPM_BRABE (Q9NDS0) Tropomyosin                                         42  0.004
REST_HUMAN (P30622) Restin (Cytoplasmic linker protein-170 alpha...    41  0.005
MYS_PODCA (Q05000) Myosin heavy chain (Fragment)                       41  0.005
CDL1_HUMAN (P21127) PITSLRE serine/threonine-protein kinase CDC2...    41  0.005
MYH7_RAT (P02564) Myosin heavy chain, cardiac muscle beta isofor...    41  0.007
GOA4_MOUSE (Q91VW5) Golgi autoantigen, golgin subfamily A member...    41  0.007
C190_DROME (Q9VJE5) Restin homolog (Cytoplasmic linker protein 1...    41  0.007
YMW7_YEAST (Q04272) Hypothetical 25.6 kDa protein in ABF2-CHL12 ...    40  0.009
YAF3_SCHPO (Q09857) Hypothetical protein C29E6.03c in chromosome I     40  0.009
MYS3_HYDAT (P39922) Myosin heavy chain, clone 203 (Fragment)           40  0.009
MYS2_YEAST (P19524) Myosin-2 (Class V unconventional myosin MYO2...    40  0.009
MYHB_CHICK (P10587) Myosin heavy chain, gizzard smooth muscle          40  0.009

>SN72_HUMAN (Q9NZZ3) SNF7 domain containing protein 2 (CGI-34)
           (HSPC177)
          Length = 219

 Score = 52.8 bits (125), Expect = 2e-06
 Identities = 29/137 (21%), Positives = 72/137 (52%), Gaps = 5/137 (3%)

Query: 257 RKLALRYARELKLVTQSREKCSSLLNRVEEVHGVVVDAESTKTVSEAMQIGARAIKE--N 314
           ++ ALR  ++ ++  Q R+  +     +E+ +  +   + TKT  +AM++G + +K+   
Sbjct: 62  KQKALRVLKQKRMYEQQRDNLAQQSFNMEQANYTIQSLKDTKTTVDAMKLGVKEMKKAYK 121

Query: 315 KISVEDVDICLRDLQESIDSQKEVEKALEQTPSYTDINDEDIEEELEELE---LALEKEA 371
           ++ ++ ++     L++ ++   E+++AL ++    +++++D+E EL+ L    LA E  +
Sbjct: 122 QVKIDQIEDLQDQLEDMMEDANEIQEALSRSYGTPELDEDDLEAELDALGDELLADEDSS 181

Query: 372 QVDTLEKTTTSEEGNAT 388
            +D         EG  T
Sbjct: 182 YLDEAASAPAIPEGVPT 198


>SN72_MOUSE (Q9D7S9) SNF7 domain containing protein 2
          Length = 219

 Score = 52.0 bits (123), Expect = 3e-06
 Identities = 29/137 (21%), Positives = 72/137 (52%), Gaps = 5/137 (3%)

Query: 257 RKLALRYARELKLVTQSREKCSSLLNRVEEVHGVVVDAESTKTVSEAMQIGARAIKE--N 314
           ++ ALR  ++ ++  Q R+  +     +E+ +  +   + TKT  +AM++G + +K+   
Sbjct: 62  KQKALRVLKQKRMYEQQRDNLAQQSFNMEQANYTIQSLKDTKTTVDAMKLGVKEMKKAYK 121

Query: 315 KISVEDVDICLRDLQESIDSQKEVEKALEQTPSYTDINDEDIEEELEELE---LALEKEA 371
           ++ ++ ++     L++ ++   E+++AL ++    +++++D+E EL+ L    LA E  +
Sbjct: 122 EVKIDQIEDLQDQLEDMMEDANEIQEALGRSYGTPELDEDDLEAELDALGDELLADEDSS 181

Query: 372 QVDTLEKTTTSEEGNAT 388
            +D         EG  T
Sbjct: 182 YLDEAASAPAIPEGVPT 198


>M24_STRPY (P12379) M protein, serotype 24 precursor
          Length = 539

 Score = 48.9 bits (115), Expect = 2e-05
 Identities = 56/225 (24%), Positives = 103/225 (44%), Gaps = 15/225 (6%)

Query: 209 ALSGASNLDCDVLYLIWTIEKLQQQLDVIDRRCELSRKSAVASLHSGNRKLALRYARELK 268
           AL GA N        I T+E  +  L+    + +L  +S V + +  + +  L  +RE K
Sbjct: 268 ALEGAMNFSTADSAKIKTLEAEKAALEA--EKADLEHQSQVLNANRQSLRRDLDASREAK 325

Query: 269 LVTQSREKCSSLLNRVEEV--HGVVVDAESTKTVSEAMQIGARAIKE-NKISVEDVDICL 325
              ++  +     N++ E     +  D ++++   + ++   + ++E NKIS        
Sbjct: 326 KQLEAEHQKLEEQNKISEASRQSLRRDLDASREAKKQLEAEHQKLEEQNKISEASRQSLR 385

Query: 326 RDLQESIDSQKEVEKALEQTPS---YTDINDEDIEE-----ELEELELALEKEAQVDTL- 376
           RDL  S +++K+VEKALE+  S     +  ++++EE     E E+ EL  + EA+   L 
Sbjct: 386 RDLDASREAKKQVEKALEEANSKLAALEKLNKELEESKKLTEKEKAELQAKLEAEAKALK 445

Query: 377 EKTTTSEEGNATLEASELLSDTLSNLKLSDRPV-GKSRTTHAASE 420
           EK     E  A L A +       + K  ++ V GK +   A ++
Sbjct: 446 EKLAKQAEELAKLRAGKASDSQTPDAKPGNKAVPGKGQAPQAGTK 490


>SNF7_YEAST (P39929) Nuclear protein SNF7
          Length = 240

 Score = 47.4 bits (111), Expect = 7e-05
 Identities = 31/126 (24%), Positives = 62/126 (48%), Gaps = 3/126 (2%)

Query: 252 LHSGNRKLALRYARELKLVTQSREKCSSLLNRVEEVHGVVVDAESTKTVSEAMQIGARAI 311
           L  GN+ +A    ++ K + Q   K    +  +E+    +  A        AMQ GA+A+
Sbjct: 55  LTKGNKVMAKNALKKKKTIEQLLSKVEGTMESMEQQLFSIESANLNLETMRAMQEGAKAM 114

Query: 312 K--ENKISVEDVDICLRDLQESIDSQKEVEKALEQTPSYTDINDEDIEEELEELELALEK 369
           K   + + ++ VD  + +++E ++   E+  A+ + P  T  N+ D +E  EEL++  ++
Sbjct: 115 KTIHSGLDIDKVDETMDEIREQVELGDEISDAISR-PLITGANEVDEDELDEELDMLAQE 173

Query: 370 EAQVDT 375
            A  +T
Sbjct: 174 NANQET 179


>CNC3_HUMAN (Q9BY43) Protein C14orf123 (HSPC134) (CDA04)
          Length = 222

 Score = 47.0 bits (110), Expect = 9e-05
 Identities = 39/172 (22%), Positives = 80/172 (45%), Gaps = 12/172 (6%)

Query: 227 IEKLQQQLDVIDRRCELSRKSAVASLHSG------NRKLALRYARELKLVTQSREKCSSL 280
           I+KL++   ++ ++ E   +     L +       N++ AL+  R  K   Q   +    
Sbjct: 23  IQKLKETEKILIKKQEFLEQKIQQELQTAKKYGTKNKRAALQALRRKKRFEQQLAQTDGT 82

Query: 281 LNRVEEVHGVVVDAESTKTVSEAMQIGARAIKE--NKISVEDVDICLRDLQESIDSQKEV 338
           L+ +E     + +A +   V   M++ A+++K+    + ++ VD  + D+ E  +  +++
Sbjct: 83  LSTLEFQREAIENATTNAEVLRTMELAAQSMKKAYQDMDIDKVDELMTDITEQQEVAQQI 142

Query: 339 EKALEQTPSYTDINDED-IEEELEELELALEKEAQVDTLEKTTTSEEGNATL 389
             A+ +   + D  DED + EELEELE   ++E   + L      EE +  L
Sbjct: 143 SDAISRPMGFRDDVDEDELLEELEELE---QEELAQELLNVGDKEEEPSVKL 191


>GOA4_HUMAN (Q13439) Golgi autoantigen, golgin subfamily A member 4
           (Trans-Golgi p230) (256 kDa golgin) (Golgin-245) (72.1
           protein)
          Length = 2230

 Score = 45.8 bits (107), Expect = 2e-04
 Identities = 50/206 (24%), Positives = 96/206 (46%), Gaps = 32/206 (15%)

Query: 228 EKLQQQLDVIDRRCELSRKSAVASLHSGNRKLALRYARELKLVTQSREKCSSLLNRVEEV 287
           E LQ+QLD  +R  EL +   +  LH          A + KL+TQ R+   +L+ ++E+ 
Sbjct: 317 EALQEQLD--ERLQELEK---IKDLHM---------AEKTKLITQLRD-AKNLIEQLEQD 361

Query: 288 HGVVVDAESTKTVSEAMQIGARAIKENKISVEDVDICLRDLQESIDSQK-----EVEKAL 342
            G+V+ AE+ + + E +++    I + +  ++ +     +L+E  +  +     E+EKAL
Sbjct: 362 KGMVI-AETKRQMHETLEMKEEEIAQLRSRIKQMTTQGEELREQKEKSERAAFEELEKAL 420

Query: 343 EQTPSYTDINDEDIEEELEELELALEKEAQVDTLEKTTTSEEGNATLEASELLSDTLSNL 402
             T   T+     ++ E++E         Q+ T+EKT+  E  +   E S +  + +  +
Sbjct: 421 S-TAQKTEEARRKLKAEMDE---------QIKTIEKTSEEERISLQQELSRVKQEVVDVM 470

Query: 403 -KLSDRPVGKSRTTHAASEGHKTANL 427
            K S+  + K +  H      K   L
Sbjct: 471 KKSSEEQIAKLQKLHEKELARKEQEL 496


>M5_STRP5 (P02977) M protein, serotype 5 precursor
          Length = 492

 Score = 43.5 bits (101), Expect = 0.001
 Identities = 47/194 (24%), Positives = 90/194 (46%), Gaps = 14/194 (7%)

Query: 228 EKLQQQLDVIDRRCELSRKSAVASLHSGNRKLALR---YARELKLVTQSREKCSSLLNRV 284
           +K +Q +  + +  EL++K     +   +RK   R    +RE K   ++  +     N++
Sbjct: 237 QKSKQNIGALKQ--ELAKKDEANKISDASRKGLRRDLDASREAKKQLEAEHQKLEEQNKI 294

Query: 285 EEVH--GVVVDAESTKTVSEAMQIGARAIKE-NKISVEDVDICLRDLQESIDSQKEVEKA 341
            E    G+  D ++++   + ++   + ++E NKIS        RDL  S +++K+VEKA
Sbjct: 295 SEASRKGLRRDLDASREAKKQLEAEQQKLEEQNKISEASRKGLRRDLDASREAKKQVEKA 354

Query: 342 LEQTPSYTDINDEDIEEELEELELALEKE-----AQVDTLEKTTTSEEGNATLEASELLS 396
           LE+  S      E + +ELEE +   EKE     A+++   K    +      E ++L +
Sbjct: 355 LEEANSKLAAL-EKLNKELEESKKLTEKEKAELQAKLEAEAKALKEQLAKQAEELAKLRA 413

Query: 397 DTLSNLKLSDRPVG 410
              S+ +  D   G
Sbjct: 414 GKASDSQTPDTKPG 427


>HCR_GORGO (Q8HZ59) Alpha helical coiled-coil rod protein
          Length = 782

 Score = 42.4 bits (98), Expect = 0.002
 Identities = 53/222 (23%), Positives = 98/222 (43%), Gaps = 34/222 (15%)

Query: 223 LIWTIEKLQQQLDVIDRRCELSR---KSAVASLHSGNRKLALRYARELKLVTQSREKCSS 279
           L+ T++ LQ+  D +    EL +   +S    L     +L  +      L  +   KC S
Sbjct: 273 LLETMQHLQEDRDSLQATAELLQVRVQSLTHILALQEEELTRKVQPSDSLEPEFTRKCQS 332

Query: 280 LLNRVEEVHGVVVDAESTKTVSEAMQIGARAIKENKISVEDVDICLRDLQESIDSQKEVE 339
           LLNR  E           K  +  +Q+ A+ + E+  SV+ +   +  LQE + SQ + +
Sbjct: 333 LLNRWRE-----------KVFALMVQLKAQEL-EHSDSVKQLKGQVASLQEKVTSQSQEQ 380

Query: 340 KALEQTPSYTDINDEDIEEELE-------ELELALEKEAQVDTLEKTTTSEEG-----NA 387
             L+Q+     + D+  E E+E       +LEL+  +EA+    ++T ++EE      NA
Sbjct: 381 AILQQS-----LQDKAAEVEVERMGAKGLQLELSRAQEARCRWQQQTASAEEQLRLVVNA 435

Query: 388 TLEASELLSDTLSNLK--LSDRPVGKSRTTHAASEGHKTANL 427
              +   L  T++ ++   +  P   +R ++A  + H    L
Sbjct: 436 VSSSQIWLETTMAKVEGAAAQLPSLNNRLSYAVRKVHTIRGL 477


>TPM_BRABE (Q9NDS0) Tropomyosin
          Length = 284

 Score = 41.6 bits (96), Expect = 0.004
 Identities = 43/174 (24%), Positives = 79/174 (44%), Gaps = 16/174 (9%)

Query: 228 EKLQQQLDVIDRRCELSRKSAVASLHSGNRKLALRYA------RELKLVTQSREKCSSLL 281
           +K++   D +D+  E S K A   L +  +K A   A      R ++LV +  ++    L
Sbjct: 48  KKIRMVEDELDKAQE-SLKEATEQLEAATKKAADAEAEVASLNRRIQLVEEELDRAQERL 106

Query: 282 NRVEEVHGVVVDAESTKTVSEAMQIGARAIKENKISVEDVDICLRDLQ--ESIDSQKEVE 339
           N   E    + D+E     SE     AR + EN+   ++  + L D+Q  E+    +E +
Sbjct: 107 NSTVEK---LTDSEKAADESER----ARKVLENRQGADEDKMELLDMQLREAKMIAEEAD 159

Query: 340 KALEQTPSYTDINDEDIEEELEELELALEKEAQVDTLEKTTTSEEGNATLEASE 393
           +  E+      I + D+E   E  +LA  K  +++   KTTT +  +   +A++
Sbjct: 160 RKYEEVARKLVITEGDLERAEERADLAETKARELEDELKTTTGQLKSMEAQATK 213


>REST_HUMAN (P30622) Restin (Cytoplasmic linker protein-170 alpha-2)
            (CLIP-170) (Reed-Sternberg intermediate filament
            associated protein)
          Length = 1427

 Score = 41.2 bits (95), Expect = 0.005
 Identities = 37/143 (25%), Positives = 66/143 (45%), Gaps = 11/143 (7%)

Query: 273  SREKCSSLLNRVEEVHGVVVDAESTKTVSEAMQIGARAIKENK---ISVEDVDICLRDLQ 329
            +RE+ S LL  +EE+      A++ +T  +AMQI  +  KE      S+ED       LQ
Sbjct: 1050 AREENSGLLQELEELRKQADKAKAAQTAEDAMQIMEQMTKEKTETLASLEDTKQTNAKLQ 1109

Query: 330  ESIDSQKEVE----KALEQTPSYTDINDEDIEEELEELELALEKEAQVDTLEKTTTSEEG 385
              +D+ KE      + L ++     + ++ +EE  +E+E    K+A     ++ +  +E 
Sbjct: 1110 NELDTLKENNLKNVEELNKSKELLTVENQKMEEFRKEIETL--KQAAAQKSQQLSALQEE 1167

Query: 386  NATL--EASELLSDTLSNLKLSD 406
            N  L  E      +  S+ KL +
Sbjct: 1168 NVKLAEELGRSRDEVTSHQKLEE 1190



 Score = 32.0 bits (71), Expect = 3.1
 Identities = 35/156 (22%), Positives = 73/156 (46%), Gaps = 10/156 (6%)

Query: 227 IEKLQQQLDVIDRRCELSRKS-AVASLHSGNRKLALRYAREL--KLVTQSREKCSSLLNR 283
           +++ QQ ++ +    +L R   A A+ H G  +  L  AR+   + V +   K   L   
Sbjct: 357 LKEKQQHIEQLLAERDLERAEVAKATSHVGEIEQELALARDGHDQHVLELEAKMDQLRTM 416

Query: 284 VEEVHGVVVDAESTKTVSEAMQIGARAIKENKISVEDVDICLRDLQESIDSQKEVEKALE 343
           VE       D E  + +++ ++   R +++ +  VE+  I   DL+     +    K LE
Sbjct: 417 VE-----AADREKVELLNQ-LEEEKRKVEDLQFRVEEESITKGDLETQTKLEHARIKELE 470

Query: 344 QTPSYTDINDEDIEEELEELELA-LEKEAQVDTLEK 378
           Q+  +     + ++ ELE+  +A + +++++  LEK
Sbjct: 471 QSLLFEKTKADKLQRELEDTRVATVSEKSRIMELEK 506


>MYS_PODCA (Q05000) Myosin heavy chain (Fragment)
          Length = 692

 Score = 41.2 bits (95), Expect = 0.005
 Identities = 40/200 (20%), Positives = 88/200 (44%), Gaps = 32/200 (16%)

Query: 227 IEKLQQQLDVIDRRCELSRKSAVASLHSGNRKLALRYARELKLVTQSREKCSSLLNRVEE 286
           +EKL+++L + +   +++ + A A+L     KL L+   E   + QS ++   L  + EE
Sbjct: 265 VEKLRRKLGMENEELQIALEEAEAALEQEEGKL-LKVQLEYTQLRQSSDR--KLSEKDEE 321

Query: 287 VHGV-------------VVDAEST----------KTVSEAMQIGARAIKENKISVED--- 320
           + G+              +D+ES           K  ++ M++ ++    N+++ E    
Sbjct: 322 LEGLRKNHQRQMESLQNTIDSESRSKAEQQKLRKKYDADMMELESQLESSNRVAAESQKQ 381

Query: 321 ---VDICLRDLQESIDSQKEVEKALEQTPSYTDINDEDIEEELEELELALEKEAQVDTLE 377
              +   +++LQ  ID +      +  + S ++    D+  +L+E  +ALE+  +   L 
Sbjct: 382 MKKLQAQIKELQSMIDDESRGRDDMRDSASRSERRANDLAVQLDEARVALEQAERARKLA 441

Query: 378 KTTTSEEGNATLEASELLSD 397
           +   SE  +   E   L ++
Sbjct: 442 ENEKSENSDRVAELQALYNN 461


>CDL1_HUMAN (P21127) PITSLRE serine/threonine-protein kinase CDC2L1
           (EC 2.7.1.37) (Galactosyltransferase associated protein
           kinase p58/GTA) (Cell division cycle 2-like 1) (CLK-1)
           (CDK11) (p58 CLK-1)
          Length = 795

 Score = 41.2 bits (95), Expect = 0.005
 Identities = 45/196 (22%), Positives = 87/196 (43%), Gaps = 21/196 (10%)

Query: 231 QQQLDVIDRRCELSRKSAVASLHSGNRKLALRYARELKLVTQSREKCSSLLNRVEEVHGV 290
           + +L+ ++R+ E  RK          +K   R A E +   ++R + S+    + E +  
Sbjct: 165 RDRLEQLERKRERERKMREQQKEQREQKERERRAEERRKEREARREVSAHHRTMREDYSD 224

Query: 291 VVDAES-----TKTVSEAMQIG----------ARA-----IKENKISVEDVDICLRDLQE 330
            V A        +   E  ++G          ARA     +KE K+   D+   L+D+ +
Sbjct: 225 KVKASHWSRSPPRPPRERFELGDGRKPGEARPARAQKPAQLKEEKMEERDLLSDLQDISD 284

Query: 331 SIDSQKEVEKALEQTPSYTDINDEDIEEELEELELALEKEAQVDTLEKTTTSEEGNATLE 390
           S       E +  ++ S ++  +E+ EEE EE   + E E + +  E+    E G+ + E
Sbjct: 285 SERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEE-EEEEEEETGSNSEE 343

Query: 391 ASELLSDTLSNLKLSD 406
           ASE  ++ +S  ++S+
Sbjct: 344 ASEQSAEEVSEEEMSE 359


>MYH7_RAT (P02564) Myosin heavy chain, cardiac muscle beta isoform
            (MyHC-beta)
          Length = 1935

 Score = 40.8 bits (94), Expect = 0.007
 Identities = 61/250 (24%), Positives = 98/250 (38%), Gaps = 46/250 (18%)

Query: 187  TQYLSVLKNEFVEGVKISLSAAALSGASNLDCDVL------------YLIWTIEKLQQQL 234
            TQ L  LK +  E VK   + A    ++  DCD+L             L   + K   ++
Sbjct: 1309 TQQLEDLKRQLEEEVKAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEV 1368

Query: 235  DVIDRRCELSRKSAVASLHSGNRKLALRYARELKLVTQSREKCSSL---LNRVE-EVHGV 290
                 + E         L    +KLA R     + V     KCSSL    +R++ E+  +
Sbjct: 1369 AQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEAVEAVNAKCSSLEKTKHRLQNEIEDL 1428

Query: 291  VVDAESTKTVSEAMQIGARAIKENKISVEDVDICLRDLQESIDSQKEV------------ 338
            +VD E +   + A+    R    +KI VE          E   SQKE             
Sbjct: 1429 MVDVERSNAAAAALDKKQRNF--DKILVEWKQKYEESQSELESSQKEARSLSTELFKLKN 1486

Query: 339  --EKALEQTPSYTDINDEDIEEELEEL------------EL-ALEKEAQVDTLEKTTTSE 383
              E++LE   ++   N ++++EE+ +L            EL  + K+ + + LE  +  E
Sbjct: 1487 AYEESLEHLETFKREN-KNLQEEISDLTEQLGSTGKSIHELEKIRKQLEAEKLELQSALE 1545

Query: 384  EGNATLEASE 393
            E  A+LE  E
Sbjct: 1546 EAEASLEHEE 1555



 Score = 31.6 bits (70), Expect = 4.1
 Identities = 36/176 (20%), Positives = 75/176 (42%), Gaps = 27/176 (15%)

Query: 227  IEKLQQQLDVIDRRCELSRKSAVASLHSGNRKLALRYARELKLVTQSREKCSSLLNRVEE 286
            +++LQ +++ ++   E  R +          KL    +REL+ +++          R+EE
Sbjct: 1108 LKELQARIEELEEELEAERTARAKV-----EKLRSDLSRELEEISE----------RLEE 1152

Query: 287  VHGVV-VDAESTKTVSEAMQIGARAIKENKISVEDVDICLR--------DLQESIDSQKE 337
              G   V  E  K      Q   R ++E  +  E     LR        +L E ID+ + 
Sbjct: 1153 AGGATSVQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQR 1212

Query: 338  VEKALEQTPSYTDINDEDIEEELEELELALEKEAQVDTLEKTTTSEEGNATLEASE 393
            V++ LE+  S   +  +D+   +E++   ++ +A ++ + +T   +      +A E
Sbjct: 1213 VKQKLEKEKSEFKLELDDVTSNMEQI---IKAKANLEKMCRTLEDQMNEHRSKAEE 1265


>GOA4_MOUSE (Q91VW5) Golgi autoantigen, golgin subfamily A member 4
            (tGolgin-1)
          Length = 2238

 Score = 40.8 bits (94), Expect = 0.007
 Identities = 47/177 (26%), Positives = 79/177 (44%), Gaps = 25/177 (14%)

Query: 231  QQQLDVIDRRCELSRKSAVASLHSGNRKLALRYARELKLV-----TQSREKCSSLLNRVE 285
            QQ+LD++ R CE   + A   L      L L++   LK +     TQ  +K   L   V+
Sbjct: 1972 QQELDILKRECE---QEAEEKLKQEQEDLELKHTSTLKQLMREFNTQLAQKEQELERTVQ 2028

Query: 286  EV--HGVVVDAESTKTVSEAMQIGARAIKENKISVEDVDICLRDLQESIDSQKEVEKALE 343
            E       V+AE  ++  E  Q   R I E +   +D+    R  +E +D+++E     E
Sbjct: 2029 ETIDKAQEVEAELLESHQEETQQLHRKIAEKE---DDLRRTARRYEEILDAREE-----E 2080

Query: 344  QTPSYTDINDEDIEEELEELELALEK--EAQVDTLEKTTTSEEGNATLEASELLSDT 398
             T   T     D++ +LEEL+   ++  E +  T +  T  E      + + L+SD+
Sbjct: 2081 MTGKVT-----DLQTQLEELQKKYQQRLEQEESTKDSVTILELQTQLAQKTTLISDS 2132


>C190_DROME (Q9VJE5) Restin homolog (Cytoplasmic linker protein 190)
            (Microtubule binding protein 190) (d-CLIP-190)
          Length = 1690

 Score = 40.8 bits (94), Expect = 0.007
 Identities = 44/212 (20%), Positives = 93/212 (43%), Gaps = 19/212 (8%)

Query: 226  TIEKLQQQLDVIDRRCELSRKSA-------------VASLHSGNRKLALRYARELKLVTQ 272
            TI+ LQ++L++ +   +   K A             V ++   N  ++   A EL  V +
Sbjct: 1081 TIKDLQERLEITNAELQHKEKMASEDAQKIADLKTLVEAIQVANANISATNA-ELSTVLE 1139

Query: 273  SREKCSSLLNRVEEVHGVVVDAESTKTVSEAMQIGARAIKENKISVEDVDICLRDLQESI 332
              +   S  N + E+  +  D  S + + +   I    +KE  + +++      +L+E +
Sbjct: 1140 VLQAEKSETNHIFELFEMEADMNSERLIEKVTGI-KEELKETHLQLDERQKKFEELEEKL 1198

Query: 333  DSQKEVEKALEQTPSYTDINDEDIEEELEELELAL-EKEAQVDTLEKTTTSEEGNATLEA 391
               ++ E+ L+Q    +     +I++ L+EL+ ++ +KE  V  LE+     E ++ +EA
Sbjct: 1199 KQAQQSEQKLQQESQTSKEKLTEIQQSLQELQDSVKQKEELVQNLEEKV--RESSSIIEA 1256

Query: 392  SELLSDTLSNLKLSDRPVGKSRTTHAASEGHK 423
                 +  SN++L ++      T     E  K
Sbjct: 1257 QNTKLNE-SNVQLENKTSCLKETQDQLLESQK 1287


>YMW7_YEAST (Q04272) Hypothetical 25.6 kDa protein in ABF2-CHL12
           intergenic region
          Length = 221

 Score = 40.4 bits (93), Expect = 0.009
 Identities = 33/137 (24%), Positives = 62/137 (45%), Gaps = 4/137 (2%)

Query: 257 RKLALRYARELKLVTQSREKCSSLLNRVEEVHGVVVDAESTKTVSEAMQIGARAIKENKI 316
           R L  R   +  L+ Q+ ++  +L N V  +   +V+    K     ++ G   +K+   
Sbjct: 63  RFLLKRIHYQEHLLQQASDQLINLENMVSTLEFKMVE----KQFINGLKNGNEILKKLNK 118

Query: 317 SVEDVDICLRDLQESIDSQKEVEKALEQTPSYTDINDEDIEEELEELELALEKEAQVDTL 376
              +VD  + D+Q+ I  Q E+ + L ++   T   ++D+++EL+ LE  L  E   +  
Sbjct: 119 EFSNVDELMDDVQDQIAYQNEINETLSRSLVGTSNYEDDLDKELDALESELNPEKMNNAK 178

Query: 377 EKTTTSEEGNATLEASE 393
                S EG  +L   E
Sbjct: 179 VANMPSTEGLPSLPQGE 195


>YAF3_SCHPO (Q09857) Hypothetical protein C29E6.03c in chromosome I
          Length = 1044

 Score = 40.4 bits (93), Expect = 0.009
 Identities = 35/146 (23%), Positives = 69/146 (46%), Gaps = 18/146 (12%)

Query: 227 IEKLQQQLDVIDRRCEL--SRKSAVASLHSGNRKLALRYARELKLVTQSREKCSSLLNRV 284
           +++LQ QL+    + E    R SA A   S    +    A ELKL   +++KCS+L  ++
Sbjct: 815 LQELQSQLNQDKNQIETLNERISAAADELSSMESINKNQANELKL---AKQKCSNLQEKI 871

Query: 285 -----------EEVHGVVVDAESTKTVSEAMQIGARAIKENKISVEDVDICLRDLQESID 333
                      E++  +  D E+    +  +    + +K    S++ V    ++ ++S++
Sbjct: 872 NFGNKLAKEHTEKISSLEKDLEAATKTASTLSKELKTVKSENDSLKSVSNDDQNKEKSVN 931

Query: 334 SQK--EVEKALEQTPSYTDINDEDIE 357
           ++K  EV +AL +     +  DE+IE
Sbjct: 932 NEKFKEVSQALAEANEKLNARDEEIE 957


>MYS3_HYDAT (P39922) Myosin heavy chain, clone 203 (Fragment)
          Length = 539

 Score = 40.4 bits (93), Expect = 0.009
 Identities = 54/231 (23%), Positives = 106/231 (45%), Gaps = 24/231 (10%)

Query: 211 SGASNLDCDVLYLIWTIEKLQQQLD---VIDRRCELSRK---SAVASLHSGNRKLALRYA 264
           S  S L   +  L+  IE+L+++L+    + ++ EL RK   S +  L           +
Sbjct: 302 SQISQLQRKIQELLAKIEELEEELENERKLRQKSELQRKELESRIEELQDQLETAGGATS 361

Query: 265 RELKLVTQSREKCSSLLNRVEEVHGV------VVDAESTKTVSEAMQIGARAIKENKISV 318
            ++++  +   +C+ L   +E ++         + A++  T++E +Q    A+K+ K  +
Sbjct: 362 AQVEVGKKREAECNRLRKEIEALNIANDAAISAIKAKTNATIAE-IQEENEAMKKAKAKL 420

Query: 319 EDVDICLR-DLQESIDSQKEVEKALEQTPSYTDINDEDIEEELEELELALEKEAQVDTLE 377
           E     L  +L E+ +S  +++K  ++T S  D N   +EE++ EL     K AQVD L 
Sbjct: 421 EKEKSALNNELNETKNSLDQIKK--QKTNS--DKNSRMLEEQINELN---SKLAQVDELH 473

Query: 378 KTTTSEEGNATLEASEL---LSDTLSNLKLSDRPVGKSRTTHAASEGHKTA 425
             + S+      E   L   LS++  NL ++ + +    +  A S+    A
Sbjct: 474 SQSESKNSKVNSELLALNSQLSESEHNLGIATKNIKTLESQLAESKNFNEA 524



 Score = 32.3 bits (72), Expect = 2.4
 Identities = 21/115 (18%), Positives = 60/115 (51%), Gaps = 9/115 (7%)

Query: 273 SREKCSSLLNRVEEVHGVVVDAESTKTVSEAMQIGARA-IKENKISVEDVDICLRDLQES 331
           +R+K S    R++E   +V   E + +  E  + G  + I + +  ++++   + +L+E 
Sbjct: 265 NRDKLSETETRLKETQDLVTKREKSISDLENAKEGLESQISQLQRKIQELLAKIEELEEE 324

Query: 332 IDSQKEVEKALEQTPSYTDINDEDIEEELE--------ELELALEKEAQVDTLEK 378
           +++++++ +  E      +   E+++++LE        ++E+  ++EA+ + L K
Sbjct: 325 LENERKLRQKSELQRKELESRIEELQDQLETAGGATSAQVEVGKKREAECNRLRK 379



 Score = 32.0 bits (71), Expect = 3.1
 Identities = 36/165 (21%), Positives = 72/165 (42%), Gaps = 5/165 (3%)

Query: 245 RKSAVASLHSGNRKLALRYARELKLVTQSREKCSSLLNRVE----EVHGVVVDAESTKTV 300
           ++   ASL +   +L     + L L T   +  SSL   +E    E H V+V  E  +  
Sbjct: 87  KEKLYASLQAETDRLITIEDKLLNLQTVKDKLESSLNEALEKLDGEEHSVLVLEEKIQEA 146

Query: 301 SEAMQIGARAIKENKISVEDVDICLRDLQESIDSQKEVEKALEQTPSYTDINDEDIEEEL 360
            E +       +E + ++  ++   ++  + ID+  E  +  ++T S  +   + ++EEL
Sbjct: 147 EEKIDELTEKTEELQSNISRLETEKQNRDKQIDTLNEDIRKQDETISKMNAEKKHVDEEL 206

Query: 361 EELELALE-KEAQVDTLEKTTTSEEGNATLEASELLSDTLSNLKL 404
           ++    L+  E + + L KT    E +      +L  +  S +KL
Sbjct: 207 KDRTEQLQAAEDKCNNLNKTKNKLESSIREIEQDLKKEKDSKMKL 251


>MYS2_YEAST (P19524) Myosin-2 (Class V unconventional myosin MYO2)
            (Type V myosin heavy chain MYO2) (Myosin V MYO2) (Cell
            divison control protein 66)
          Length = 1574

 Score = 40.4 bits (93), Expect = 0.009
 Identities = 46/191 (24%), Positives = 92/191 (48%), Gaps = 22/191 (11%)

Query: 249  VASLHSGNRKLALRYARELKLVTQSREKCSSLLNRVEEVHGVVVDAESTK------TVSE 302
            +AS    N+++  R  +EL++  +   K    L  +++ H + +D + +K      T+  
Sbjct: 954  LASKVKENKEMTERI-KELQVQVEESAKLQETLENMKKEHLIDIDNQKSKDMELQKTIEN 1012

Query: 303  AMQIGARAIKENKISVEDVDICLRDLQESIDSQKEVEKALEQTP----SYTDINDEDIEE 358
             +Q   + +K+ ++ +ED+     +L+E  +S+K++E+ LEQT      Y  +N  D++ 
Sbjct: 1013 NLQSTEQTLKDAQLELEDMVKQHDELKE--ESKKQLEE-LEQTKKTLVEYQTLNG-DLQN 1068

Query: 359  ELEELELALEKEAQVDTLEKTTTSEEGNATLE------ASELLSDTLSNLKLSDRPVG-K 411
            E++ L+  + +     +L   TTS      L+      AS   +  L N  LS   +  K
Sbjct: 1069 EVKSLKEEIARLQTAMSLGTVTTSVLPQTPLKDVMGGGASNFNNMMLENSDLSPNDLNLK 1128

Query: 412  SRTTHAASEGH 422
            SR+T ++   H
Sbjct: 1129 SRSTPSSGNNH 1139


>MYHB_CHICK (P10587) Myosin heavy chain, gizzard smooth muscle
          Length = 1978

 Score = 40.4 bits (93), Expect = 0.009
 Identities = 43/163 (26%), Positives = 70/163 (42%), Gaps = 36/163 (22%)

Query: 228  EKLQQQLDVIDRRCELSRKSAVASLHSGNRKLALRYARELKLVTQSREKCSSLLNRVEEV 287
            EK +Q+L+ I R+ E       + LH    +L  + A     + +  E+  + L R+E  
Sbjct: 1052 EKSRQELEKIKRKLE----GESSDLHEQIAELQAQIAELKAQLAKKEEELQAALARLE-- 1105

Query: 288  HGVVVDAESTKTVSEAMQIGARAIKENKISVEDVDICLRDLQESIDSQKEVEKALEQTPS 347
                 D  S K           A+K+    + +++  + DLQE ++S+K      E+   
Sbjct: 1106 -----DETSQKN---------NALKK----IRELESHISDLQEDLESEKAARNKAEK--- 1144

Query: 348  YTDINDEDIEEELEELELALEKEAQVDTLEKTTTSEEGNATLE 390
                   D+ EELE L+  LE     DTL+ T T +E  A  E
Sbjct: 1145 ----QKRDLSEELEALKTELE-----DTLDTTATQQELRAKRE 1178



 Score = 37.4 bits (85), Expect = 0.075
 Identities = 41/175 (23%), Positives = 81/175 (45%), Gaps = 22/175 (12%)

Query: 266  ELKLVTQSREKCSSLLNRVEEVHGVVVDAES---------TKTVSEAMQIGARAIKENKI 316
            EL+   + ++K  + L  +E+ H  + + ++         T+  +EA ++  R +   K 
Sbjct: 865  ELQRTKERQQKAEAELKELEQKHTQLCEEKNLLQEKLQAETELYAEAEEMRVR-LAAKKQ 923

Query: 317  SVEDVDICLRDLQESIDSQKEVEKALEQTPSYTDINDEDIEEELEELELALEKEAQVDTL 376
             +E++   L +++  I+ ++E  + L+           D+EE+LEE E A +K      L
Sbjct: 924  ELEEI---LHEMEARIEEEEERSQQLQAEKKKMQQQMLDLEEQLEEEEAARQKL----QL 976

Query: 377  EKTTTSEEGNATLEASELLSDTLSNLKLSDRPVGKSR----TTHAASEGHKTANL 427
            EK  T++     +E   L+ +  +N    +R + + R    TT+ A E  K  NL
Sbjct: 977  EK-VTADGKIKKMEDDILIMEDQNNKLTKERKLLEERVSDLTTNLAEEEEKAKNL 1030



 Score = 32.3 bits (72), Expect = 2.4
 Identities = 39/162 (24%), Positives = 67/162 (41%), Gaps = 21/162 (12%)

Query: 259  LALRYARELKLVTQSREKCSSLLNRVEEVHGVVVDAESTK--------TVSEAMQIGARA 310
            L  +Y+   ++ T+  EK   L   VE V  ++ +AES          T+   +Q     
Sbjct: 1269 LQSKYSDGERVRTELNEKVHKLQIEVENVTSLLNEAESKNIKLTKDVATLGSQLQDTQEL 1328

Query: 311  IKENKISVEDVDICLRDL-------QESIDSQKEVEKALEQTPSYTDINDEDIEEELEEL 363
            ++E      +V   LR L       QE +D + E ++ LE+  S   I   D +++L+E 
Sbjct: 1329 LQEETRQKLNVTTKLRQLEDDKNSLQEQLDEEVEAKQNLERHISTLTIQLSDSKKKLQEF 1388

Query: 364  ELALE------KEAQVDTLEKTTTSEEGNATLEASELLSDTL 399
               +E      K+ Q +    T   EE  A+ +  E   + L
Sbjct: 1389 TATVETMEEGKKKLQREIESLTQQFEEKAASYDKLEKTKNRL 1430



 Score = 30.8 bits (68), Expect = 7.0
 Identities = 35/153 (22%), Positives = 68/153 (43%), Gaps = 9/153 (5%)

Query: 226  TIEKLQQQLD--VIDRRCELSRKSAVASLHSGNRKLALRYARELKLVTQSREKCSSLLNR 283
            T  +LQQ+LD  V+D     +++  V++L    +K     A E  + ++  ++       
Sbjct: 1426 TKNRLQQELDDLVVDLD---NQRQLVSNLEKKQKKFDQMLAEEKNISSKYADERDRAEAE 1482

Query: 284  VEEVHGVVVD-AESTKTVSEAMQIGARAIKENKISVEDVDICLRDLQESIDSQKEVEKAL 342
              E     +  A + +   EA +   R  K  K  +ED+     D+ +++   ++ ++ L
Sbjct: 1483 AREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRTL 1542

Query: 343  EQTPSYTDINDEDIEEEL---EELELALEKEAQ 372
            EQ         E++E+EL   E+ +L LE   Q
Sbjct: 1543 EQQVEEMKTQLEELEDELQAAEDAKLRLEVNMQ 1575


  Database: sprot
    Posted date:  Nov 25, 2004 10:54 AM
  Number of letters in database: 59,974,054
  Number of sequences in database:  164,201
  
Lambda     K      H
   0.315    0.132    0.368 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 46,808,163
Number of Sequences: 164201
Number of extensions: 1928410
Number of successful extensions: 10389
Number of sequences better than 10.0: 377
Number of HSP's better than 10.0 without gapping: 50
Number of HSP's successfully gapped in prelim test: 335
Number of HSP's that attempted gapping in prelim test: 9531
Number of HSP's gapped (non-prelim): 923
length of query: 429
length of database: 59,974,054
effective HSP length: 113
effective length of query: 316
effective length of database: 41,419,341
effective search space: 13088511756
effective search space used: 13088511756
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 67 (30.4 bits)