BLAST2 result
BLASTP 2.2.2 [Dec-14-2001]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= AC137546.2 - phase: 0
(623 letters)
Database: sprot
164,201 sequences; 59,974,054 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
MAOX_VITVI (P51615) NADP-dependent malic enzyme (EC 1.1.1.40) (N... 968 0.0
MAOX_POPTR (P34105) NADP-dependent malic enzyme (EC 1.1.1.40) (N... 959 0.0
MAOX_PHAVU (P12628) NADP-dependent malic enzyme (EC 1.1.1.40) (N... 932 0.0
MAOC_FLAPR (P36444) NADP-dependent malic enzyme, chloroplast pre... 924 0.0
MAOX_MESCR (P37223) NADP-dependent malic enzyme (EC 1.1.1.40) (N... 904 0.0
MAOC_FLATR (P22178) NADP-dependent malic enzyme, chloroplast pre... 897 0.0
MAOC_ORYSA (P43279) NADP-dependent malic enzyme, chloroplast pre... 897 0.0
MAOC_LYCES (P37222) NADP-dependent malic enzyme, chloroplast (EC... 875 0.0
MAOC_MAIZE (P16243) NADP-dependent malic enzyme, chloroplast pre... 839 0.0
MAOX_ANAPL (P28227) NADP-dependent malic enzyme (EC 1.1.1.40) (N... 555 e-157
MAOX_COLLI (P40927) NADP-dependent malic enzyme (EC 1.1.1.40) (N... 552 e-157
MAOX_HUMAN (P48163) NADP-dependent malic enzyme (EC 1.1.1.40) (N... 538 e-152
MAOX_PIG (Q29558) NADP-dependent malic enzyme (EC 1.1.1.40) (NAD... 538 e-152
MAOX_RAT (P13697) NADP-dependent malic enzyme (EC 1.1.1.40) (NAD... 536 e-152
MAOX_MOUSE (P06801) NADP-dependent malic enzyme (EC 1.1.1.40) (N... 533 e-151
MAOM_HUMAN (P23368) NAD-dependent malic enzyme, mitochondrial pr... 530 e-150
MAON_HUMAN (Q16798) NADP-dependent malic enzyme, mitochondrial p... 527 e-149
MAOM_MOUSE (Q99KE1) NAD-dependent malic enzyme, mitochondrial pr... 523 e-148
MAOM_ASCSU (P27443) NAD-dependent malic enzyme, mitochondrial pr... 488 e-137
MAO1_ECOLI (P26616) NAD-dependent malic enzyme (EC 1.1.1.38) (NA... 429 e-119
>MAOX_VITVI (P51615) NADP-dependent malic enzyme (EC 1.1.1.40)
(NADP-ME)
Length = 591
Score = 968 bits (2503), Expect = 0.0
Identities = 474/562 (84%), Positives = 525/562 (93%)
Query: 1 MESTLKSFRDGESVLDLSPRSAVGGGVEDVYGEDCATEDQLVTPWTFSVASGYSLLRDPQ 60
MESTLK RDG SVLDL P++ VGGGVED+YGED ATEDQLVTPWT SVASGYSLLRDP+
Sbjct: 1 MESTLKDIRDGASVLDLDPKATVGGGVEDLYGEDFATEDQLVTPWTVSVASGYSLLRDPR 60
Query: 61 YNKGLAFTEKERDAHYLRGLLPPTVSSQQLQEKKLMHNIRQYEVPLQKYVAMMDLQERNE 120
+NKGLAF +KERDAHYL GLLPP VS+Q+LQE+KLM++IRQY+VPLQKY+AMMDLQERNE
Sbjct: 61 HNKGLAFNDKERDAHYLCGLLPPVVSTQELQERKLMNSIRQYQVPLQKYMAMMDLQERNE 120
Query: 121 RLFYKLLIDNVEELLPIVYTPVVGEACQKYGSIYKRPQGLYISLKEKGKILEVLKNWPER 180
RLFYKLLIDNVEELLP+VYTP VGEACQKYGSI++RPQGLYISLKEKGKILEVLKNWPER
Sbjct: 121 RLFYKLLIDNVEELLPVVYTPTVGEACQKYGSIFRRPQGLYISLKEKGKILEVLKNWPER 180
Query: 181 SIQVIVVTDGERILGLGDLGCQGMGIPVGKLALYSALGGVRPSACLPVTIDVGTNNEKLL 240
IQVIVVTDGERILGLGDLGCQGMGIPVGKL+LY+ALGGVRPSACLP+TIDVGTNNEKLL
Sbjct: 181 RIQVIVVTDGERILGLGDLGCQGMGIPVGKLSLYTALGGVRPSACLPITIDVGTNNEKLL 240
Query: 241 NDEFYIGLRQKRATGKEYYDLLHEFMTAVKQNYGEKVLVQFEDFANHNAFELLAKYGTTH 300
+EFYIGL+Q+RATGKEY + L EFM+ VKQNYGEKVL+QFEDFANHNAF+LLAKYGTTH
Sbjct: 241 ANEFYIGLKQRRATGKEYSEFLQEFMSPVKQNYGEKVLIQFEDFANHNAFDLLAKYGTTH 300
Query: 301 LVFNDDIQGTAAVVLAGVVASLKLIGGTLPEHTFLFLGAGEAGTGIAELIALEMSKQTKA 360
L FNDDIQGTA+VVLAG+V++L+L+GGTL +H FLFLGAGEAGTGIAELIALEMSKQTK
Sbjct: 301 LAFNDDIQGTASVVLAGIVSALRLLGGTLADHKFLFLGAGEAGTGIAELIALEMSKQTKC 360
Query: 361 PIEESRKKIWLVDSKGLIVSSRANSLQHFKKPWAHEHEPVSTLLDAVKIIKPTVLIGSSG 420
PIEE+RKKIWLVDSKGLIV SR +SLQ FKKPWAHEHEPV LLDAVK+IKPTVLIGSSG
Sbjct: 361 PIEETRKKIWLVDSKGLIVGSRKDSLQQFKKPWAHEHEPVKDLLDAVKVIKPTVLIGSSG 420
Query: 421 VGKTFTKEVVEAMTEINKIPLILALSNPTSQSECTAEEAYTWSEGRAIFASGSPFDPVEY 480
VGK FTKEV+EAM N+ PLILALSNPTSQSECTAEEAYTW++GRAIFASGSPFDPVEY
Sbjct: 421 VGKAFTKEVIEAMASCNEKPLILALSNPTSQSECTAEEAYTWTQGRAIFASGSPFDPVEY 480
Query: 481 KGKTYYSGQSNNAYIFPGFGLGIVMSGAIRVHDDMLLAASEALAKQVTEENYKKGLTYPP 540
GKT+ GQ+NNAYIFPG G+G+V+SGAIRVHD+MLLAASEALA+QVT+EN+ KGL YPP
Sbjct: 481 NGKTFVPGQANNAYIFPGLGMGLVISGAIRVHDEMLLAASEALARQVTQENFDKGLIYPP 540
Query: 541 FSDIRKISANIAANVAAKAYEL 562
FS+IRKISA+IAANVAAKAYEL
Sbjct: 541 FSNIRKISAHIAANVAAKAYEL 562
>MAOX_POPTR (P34105) NADP-dependent malic enzyme (EC 1.1.1.40)
(NADP-ME)
Length = 591
Score = 959 bits (2480), Expect = 0.0
Identities = 469/562 (83%), Positives = 520/562 (92%)
Query: 1 MESTLKSFRDGESVLDLSPRSAVGGGVEDVYGEDCATEDQLVTPWTFSVASGYSLLRDPQ 60
MESTLK RDG SVLD+ P+S VGGGVEDVYGED ATEDQLVTPWT SVASGY+LLRDP
Sbjct: 1 MESTLKEMRDGASVLDMDPKSTVGGGVEDVYGEDRATEDQLVTPWTISVASGYTLLRDPH 60
Query: 61 YNKGLAFTEKERDAHYLRGLLPPTVSSQQLQEKKLMHNIRQYEVPLQKYVAMMDLQERNE 120
+NKGLAFTEKERDAHYLRGLLPPT SQQLQEKKLM+ IRQY++PLQKY AMM+L+ERNE
Sbjct: 61 HNKGLAFTEKERDAHYLRGLLPPTTISQQLQEKKLMNTIRQYQLPLQKYTAMMELEERNE 120
Query: 121 RLFYKLLIDNVEELLPIVYTPVVGEACQKYGSIYKRPQGLYISLKEKGKILEVLKNWPER 180
RLFYKLLIDNVEELLP+VYTP VGEACQKYGSI+KRPQGLYISLKEKGK+L+VLKNWP++
Sbjct: 121 RLFYKLLIDNVEELLPVVYTPTVGEACQKYGSIFKRPQGLYISLKEKGKVLDVLKNWPQK 180
Query: 181 SIQVIVVTDGERILGLGDLGCQGMGIPVGKLALYSALGGVRPSACLPVTIDVGTNNEKLL 240
SIQVIVVTDGERILGLGDLGCQG+GIPVGKL+LY+ALGGVRPSACLPVTIDVGTNNE+LL
Sbjct: 181 SIQVIVVTDGERILGLGDLGCQGIGIPVGKLSLYTALGGVRPSACLPVTIDVGTNNEQLL 240
Query: 241 NDEFYIGLRQKRATGKEYYDLLHEFMTAVKQNYGEKVLVQFEDFANHNAFELLAKYGTTH 300
DEFYIGLRQ+RATG+EY +LLHEFMTAVKQNYGEKVL+QFEDFANHNAF+LLAKYGTTH
Sbjct: 241 KDEFYIGLRQRRATGQEYSELLHEFMTAVKQNYGEKVLIQFEDFANHNAFDLLAKYGTTH 300
Query: 301 LVFNDDIQGTAAVVLAGVVASLKLIGGTLPEHTFLFLGAGEAGTGIAELIALEMSKQTKA 360
LVFNDDIQGTAAVVLAG++++LKL+GG+L +HTFLFLGAGEAGTGIAELIALEMS+++K
Sbjct: 301 LVFNDDIQGTAAVVLAGLISALKLLGGSLADHTFLFLGAGEAGTGIAELIALEMSRRSKT 360
Query: 361 PIEESRKKIWLVDSKGLIVSSRANSLQHFKKPWAHEHEPVSTLLDAVKIIKPTVLIGSSG 420
P+EE+RKKIWL DSKGLIVSSR SLQHFKKPWAHEHEPV LL+ VK IKP VLIG+SG
Sbjct: 361 PLEETRKKIWLTDSKGLIVSSRKESLQHFKKPWAHEHEPVKGLLEVVKAIKPIVLIGTSG 420
Query: 421 VGKTFTKEVVEAMTEINKIPLILALSNPTSQSECTAEEAYTWSEGRAIFASGSPFDPVEY 480
VGKTFTKEV+EAM N+ PLILALSNPTSQSECTA+EAYTW++G+AIFASGSPFDPVEY
Sbjct: 421 VGKTFTKEVIEAMASFNEKPLILALSNPTSQSECTAQEAYTWTKGKAIFASGSPFDPVEY 480
Query: 481 KGKTYYSGQSNNAYIFPGFGLGIVMSGAIRVHDDMLLAASEALAKQVTEENYKKGLTYPP 540
+GK + GQSNNAYIFPG GLG+V+SGAIRVHDDMLLAA+EALA Q+ EE KGL YPP
Sbjct: 481 EGKVFVPGQSNNAYIFPGLGLGLVISGAIRVHDDMLLAAAEALAGQIKEEYLAKGLIYPP 540
Query: 541 FSDIRKISANIAANVAAKAYEL 562
S+IRKIS IAANVAAKAYEL
Sbjct: 541 LSNIRKISVQIAANVAAKAYEL 562
>MAOX_PHAVU (P12628) NADP-dependent malic enzyme (EC 1.1.1.40)
(NADP-ME)
Length = 589
Score = 932 bits (2408), Expect = 0.0
Identities = 457/539 (84%), Positives = 503/539 (92%)
Query: 24 GGGVEDVYGEDCATEDQLVTPWTFSVASGYSLLRDPQYNKGLAFTEKERDAHYLRGLLPP 83
GGGV D+YGED ATED L+TPWTFSVASG SLLRDP+YNKGLAFTE ERDAHYLRGLLPP
Sbjct: 22 GGGVRDLYGEDSATEDHLITPWTFSVASGCSLLRDPRYNKGLAFTEGERDAHYLRGLLPP 81
Query: 84 TVSSQQLQEKKLMHNIRQYEVPLQKYVAMMDLQERNERLFYKLLIDNVEELLPIVYTPVV 143
+V +Q+LQEK+LMHN+RQYEVPL +Y+A+MDLQERNERLFYKLLIDNV ELLP+VYTP V
Sbjct: 82 SVFNQELQEKRLMHNLRQYEVPLHRYMALMDLQERNERLFYKLLIDNVAELLPVVYTPTV 141
Query: 144 GEACQKYGSIYKRPQGLYISLKEKGKILEVLKNWPERSIQVIVVTDGERILGLGDLGCQG 203
GEACQKYGSI++RPQGLYISLKEKGKILEVLKNWPE+SIQVIVVTDGERILGLGDLGCQG
Sbjct: 142 GEACQKYGSIFRRPQGLYISLKEKGKILEVLKNWPEKSIQVIVVTDGERILGLGDLGCQG 201
Query: 204 MGIPVGKLALYSALGGVRPSACLPVTIDVGTNNEKLLNDEFYIGLRQKRATGKEYYDLLH 263
MGIPVGKL+LY+ALGGVRPS+CLPVTIDVGTNNEKLLNDEFYIGLRQ+RATG+EY L
Sbjct: 202 MGIPVGKLSLYTALGGVRPSSCLPVTIDVGTNNEKLLNDEFYIGLRQRRATGQEYATFLD 261
Query: 264 EFMTAVKQNYGEKVLVQFEDFANHNAFELLAKYGTTHLVFNDDIQGTAAVVLAGVVASLK 323
EFM AVKQNYGEKVLVQFEDFANHNAF+LL KY ++HLVFNDDIQGTA+VVLAG++ASLK
Sbjct: 262 EFMRAVKQNYGEKVLVQFEDFANHNAFDLLEKYSSSHLVFNDDIQGTASVVLAGLLASLK 321
Query: 324 LIGGTLPEHTFLFLGAGEAGTGIAELIALEMSKQTKAPIEESRKKIWLVDSKGLIVSSRA 383
L+GGTL +HTFLFLGAGEAGTGIAELIA+E+SKQTKAP+EE+RKKIWLVDSKGLIVSSR
Sbjct: 322 LVGGTLADHTFLFLGAGEAGTGIAELIAVEVSKQTKAPVEETRKKIWLVDSKGLIVSSRL 381
Query: 384 NSLQHFKKPWAHEHEPVSTLLDAVKIIKPTVLIGSSGVGKTFTKEVVEAMTEINKIPLIL 443
SLQ FKKPWAHEHEPV LL+AVK IKPTVLIGSSG GKTFTKEVVE M +N+ PLIL
Sbjct: 382 ESLQQFKKPWAHEHEPVKGLLEAVKAIKPTVLIGSSGAGKTFTKEVVETMASLNEKPLIL 441
Query: 444 ALSNPTSQSECTAEEAYTWSEGRAIFASGSPFDPVEYKGKTYYSGQSNNAYIFPGFGLGI 503
ALSNPTSQSECTAEEAYTWS+GRAIFASGSPFDPVEY+GK + GQ+NNAYIFPGFGLG+
Sbjct: 442 ALSNPTSQSECTAEEAYTWSKGRAIFASGSPFDPVEYEGKLFVPGQANNAYIFPGFGLGL 501
Query: 504 VMSGAIRVHDDMLLAASEALAKQVTEENYKKGLTYPPFSDIRKISANIAANVAAKAYEL 562
+MSGAIRV D+MLLAASEALA QV+EENY KGL YPPF++IRKISANIAA VAAKAY+L
Sbjct: 502 IMSGAIRVRDEMLLAASEALAAQVSEENYDKGLIYPPFTNIRKISANIAAKVAAKAYDL 560
>MAOC_FLAPR (P36444) NADP-dependent malic enzyme, chloroplast
precursor (EC 1.1.1.40) (NADP-ME)
Length = 647
Score = 924 bits (2388), Expect = 0.0
Identities = 445/544 (81%), Positives = 504/544 (91%)
Query: 19 PRSAVGGGVEDVYGEDCATEDQLVTPWTFSVASGYSLLRDPQYNKGLAFTEKERDAHYLR 78
P + VGGGVEDVYGED ATED +TPW+ SVASGYSLLRDP +NKGLAFTEKERDAHYLR
Sbjct: 75 PTAVVGGGVEDVYGEDSATEDHFITPWSVSVASGYSLLRDPHHNKGLAFTEKERDAHYLR 134
Query: 79 GLLPPTVSSQQLQEKKLMHNIRQYEVPLQKYVAMMDLQERNERLFYKLLIDNVEELLPIV 138
GLLPP V + LQ KK+MHNIRQYEVPLQ+Y AMMDLQERNERLFYKLLI+N+EELLPIV
Sbjct: 135 GLLPPVVVNHDLQVKKMMHNIRQYEVPLQRYQAMMDLQERNERLFYKLLIENIEELLPIV 194
Query: 139 YTPVVGEACQKYGSIYKRPQGLYISLKEKGKILEVLKNWPERSIQVIVVTDGERILGLGD 198
YTP VGEACQKYG+I+K PQGLYISLK+KGK+LE+LKNWP++ IQVIVVTDGERILGLGD
Sbjct: 195 YTPTVGEACQKYGTIFKNPQGLYISLKDKGKVLEILKNWPQKKIQVIVVTDGERILGLGD 254
Query: 199 LGCQGMGIPVGKLALYSALGGVRPSACLPVTIDVGTNNEKLLNDEFYIGLRQKRATGKEY 258
LGCQGMGIPVGKL+LY+ALGG+RPSACLP+TIDVGTNNEK+LNDEFYIGLRQ+RA+GKEY
Sbjct: 255 LGCQGMGIPVGKLSLYTALGGIRPSACLPITIDVGTNNEKMLNDEFYIGLRQRRASGKEY 314
Query: 259 YDLLHEFMTAVKQNYGEKVLVQFEDFANHNAFELLAKYGTTHLVFNDDIQGTAAVVLAGV 318
+L++EFM+AVKQNYGEKVL+QFEDFANHNAF+LL KY TTHLVFNDDIQGTA+VVLAG+
Sbjct: 315 AELMNEFMSAVKQNYGEKVLIQFEDFANHNAFDLLEKYRTTHLVFNDDIQGTASVVLAGL 374
Query: 319 VASLKLIGGTLPEHTFLFLGAGEAGTGIAELIALEMSKQTKAPIEESRKKIWLVDSKGLI 378
+++LKL+GG+L +H FLFLGAGEAGTGIAELIALE+SKQT AP+EE+RKKIWLVDSKGLI
Sbjct: 375 ISALKLVGGSLADHKFLFLGAGEAGTGIAELIALEISKQTNAPLEETRKKIWLVDSKGLI 434
Query: 379 VSSRANSLQHFKKPWAHEHEPVSTLLDAVKIIKPTVLIGSSGVGKTFTKEVVEAMTEINK 438
V SR +SLQHFKKPWAH+HEPV+ LDAVK IKPTVLIGSSG G+TFTKEVVEAM+ N+
Sbjct: 435 VRSRLDSLQHFKKPWAHDHEPVNKFLDAVKAIKPTVLIGSSGAGQTFTKEVVEAMSSFNE 494
Query: 439 IPLILALSNPTSQSECTAEEAYTWSEGRAIFASGSPFDPVEYKGKTYYSGQSNNAYIFPG 498
P+ILALSNPTSQSECTAE+AYTWSEGR IFASGSPF PVEY GK Y SGQSNNAYIFPG
Sbjct: 495 KPIILALSNPTSQSECTAEQAYTWSEGRTIFASGSPFAPVEYNGKVYVSGQSNNAYIFPG 554
Query: 499 FGLGIVMSGAIRVHDDMLLAASEALAKQVTEENYKKGLTYPPFSDIRKISANIAANVAAK 558
FGLG+++SGAIRVHD+MLLAASEALA+QVT+E++ GL YPPF++IRKISA+IAA VAAK
Sbjct: 555 FGLGLIISGAIRVHDEMLLAASEALAEQVTQEHFDNGLIYPPFTNIRKISAHIAAKVAAK 614
Query: 559 AYEL 562
AYEL
Sbjct: 615 AYEL 618
>MAOX_MESCR (P37223) NADP-dependent malic enzyme (EC 1.1.1.40)
(NADP-ME)
Length = 585
Score = 904 bits (2335), Expect = 0.0
Identities = 438/540 (81%), Positives = 498/540 (92%)
Query: 23 VGGGVEDVYGEDCATEDQLVTPWTFSVASGYSLLRDPQYNKGLAFTEKERDAHYLRGLLP 82
+ GGV DVYGE+ AT+DQLVTPW+FSVA G+SLLRDPQ+NKGLAFTEKERDAH+LRGLLP
Sbjct: 17 ITGGVADVYGEEFATQDQLVTPWSFSVACGHSLLRDPQHNKGLAFTEKERDAHFLRGLLP 76
Query: 83 PTVSSQQLQEKKLMHNIRQYEVPLQKYVAMMDLQERNERLFYKLLIDNVEELLPIVYTPV 142
P V SQ+LQEKK + +RQY+VPLQKY+AMMDLQERNE+LFYKLL+D+VEELLP+VYTP
Sbjct: 77 PVVLSQELQEKKFLTTLRQYQVPLQKYMAMMDLQERNEKLFYKLLVDHVEELLPLVYTPT 136
Query: 143 VGEACQKYGSIYKRPQGLYISLKEKGKILEVLKNWPERSIQVIVVTDGERILGLGDLGCQ 202
VGE CQKYGSI++RPQGL+ISLK+KG+ILE+L+NWPE+ IQVIVVTDGERILGLGDLGCQ
Sbjct: 137 VGEGCQKYGSIFRRPQGLFISLKDKGRILELLRNWPEKKIQVIVVTDGERILGLGDLGCQ 196
Query: 203 GMGIPVGKLALYSALGGVRPSACLPVTIDVGTNNEKLLNDEFYIGLRQKRATGKEYYDLL 262
GMGIPVGKL+LYSALGGV PSACLP+T+DVGTNN+KLL+DEFYIGL+QKRATG+EY + +
Sbjct: 197 GMGIPVGKLSLYSALGGVCPSACLPITLDVGTNNQKLLDDEFYIGLKQKRATGEEYAEFV 256
Query: 263 HEFMTAVKQNYGEKVLVQFEDFANHNAFELLAKYGTTHLVFNDDIQGTAAVVLAGVVASL 322
EFM+AVKQNYGEK+LVQFEDFANHNAFELL KY TTHLVFNDDIQGTA+VVLAG++ASL
Sbjct: 257 QEFMSAVKQNYGEKILVQFEDFANHNAFELLEKYRTTHLVFNDDIQGTASVVLAGLIASL 316
Query: 323 KLIGGTLPEHTFLFLGAGEAGTGIAELIALEMSKQTKAPIEESRKKIWLVDSKGLIVSSR 382
KL+GGTL +H FLFLGAGEAGTGIAELIALEMSK+TKAP+E+ RKKIWLVDSKGL+VSSR
Sbjct: 317 KLLGGTLADHKFLFLGAGEAGTGIAELIALEMSKKTKAPVEQMRKKIWLVDSKGLVVSSR 376
Query: 383 ANSLQHFKKPWAHEHEPVSTLLDAVKIIKPTVLIGSSGVGKTFTKEVVEAMTEINKIPLI 442
+LQ FK PWAHEHEP++TL+DAV+ IKPTVLIG+SG GK FTKEVVEAM IN PLI
Sbjct: 377 KETLQQFKLPWAHEHEPITTLIDAVQAIKPTVLIGTSGKGKQFTKEVVEAMANINAKPLI 436
Query: 443 LALSNPTSQSECTAEEAYTWSEGRAIFASGSPFDPVEYKGKTYYSGQSNNAYIFPGFGLG 502
LALSNPTSQSECTAEEAYTWS+G AIFASGSPFDPVEY+G+T+ GQ+NNAYIFPGFGLG
Sbjct: 437 LALSNPTSQSECTAEEAYTWSQGHAIFASGSPFDPVEYEGRTFVPGQANNAYIFPGFGLG 496
Query: 503 IVMSGAIRVHDDMLLAASEALAKQVTEENYKKGLTYPPFSDIRKISANIAANVAAKAYEL 562
++M GAIRVHDDMLLAASEALA QVT E++ KGL YPPF DIRKISA+IAA VAAKAYEL
Sbjct: 497 LIMCGAIRVHDDMLLAASEALASQVTGEHFIKGLIYPPFKDIRKISAHIAAGVAAKAYEL 556
>MAOC_FLATR (P22178) NADP-dependent malic enzyme, chloroplast
precursor (EC 1.1.1.40) (NADP-ME)
Length = 648
Score = 897 bits (2318), Expect = 0.0
Identities = 435/545 (79%), Positives = 498/545 (90%), Gaps = 1/545 (0%)
Query: 19 PRSAVGGGVEDVYGEDCATEDQLVTPWTFSVASGYSLLRDPQYNKGLAFTEKERDAHYLR 78
P +AVGGGVED+YGED ATED +TPW+ SVASGYSLLRDP +NKGLAFTEKERDAH+LR
Sbjct: 75 PFAAVGGGVEDMYGEDTATEDHYITPWSVSVASGYSLLRDPHHNKGLAFTEKERDAHFLR 134
Query: 79 GLLPPTVSSQQLQEKKLMHNIRQYEVPLQKYVAMMDLQERNERLFYKLLIDNVEELLPIV 138
GLLPP V + LQ KK+MHNIRQY+VPLQ+Y AMMDLQ+RNERLFYKLLI+NVEELLPIV
Sbjct: 135 GLLPPVVVNHDLQVKKMMHNIRQYQVPLQRYQAMMDLQQRNERLFYKLLIENVEELLPIV 194
Query: 139 YTPVVGEACQKYGSIYKRPQGLYISLKEKGKILEVLKNWPERSIQVIVVTDGERILGLGD 198
YTP VGEACQKYGSI++ QGL+ISLK+KG+ILE+LKNWP + IQVIVVTDGERILGLGD
Sbjct: 195 YTPTVGEACQKYGSIFENSQGLFISLKDKGRILEILKNWPHKKIQVIVVTDGERILGLGD 254
Query: 199 LGCQGMGIPVGKLALYSALGGVRPSACLPVTIDVGTNNEKLLND-EFYIGLRQKRATGKE 257
LGCQGMGIPVGKLALY+ALGGVRPSACLP+TIDVGTNNEKLLND EFYIGL+QKRA G+E
Sbjct: 255 LGCQGMGIPVGKLALYTALGGVRPSACLPITIDVGTNNEKLLNDDEFYIGLKQKRAAGQE 314
Query: 258 YYDLLHEFMTAVKQNYGEKVLVQFEDFANHNAFELLAKYGTTHLVFNDDIQGTAAVVLAG 317
Y +L++EFM+AVKQNYGE +L+QFEDFANHNAF+LL KY TTHLVFNDDIQGTA+VVL G
Sbjct: 315 YAELMNEFMSAVKQNYGENLLIQFEDFANHNAFDLLEKYRTTHLVFNDDIQGTASVVLGG 374
Query: 318 VVASLKLIGGTLPEHTFLFLGAGEAGTGIAELIALEMSKQTKAPIEESRKKIWLVDSKGL 377
++++LKL+GG+L + FLFLGAGEAGTGIAELIALE+SKQT P+EESRKK+WLVDSKGL
Sbjct: 375 LISALKLVGGSLADQKFLFLGAGEAGTGIAELIALEISKQTNIPLEESRKKVWLVDSKGL 434
Query: 378 IVSSRANSLQHFKKPWAHEHEPVSTLLDAVKIIKPTVLIGSSGVGKTFTKEVVEAMTEIN 437
IV SR +SLQHFKKPWAH+HEPV+ LDA+K I+PTVLIGSSG G+TFTKEVVE M+ +N
Sbjct: 435 IVRSRLDSLQHFKKPWAHDHEPVNEFLDAIKTIRPTVLIGSSGTGQTFTKEVVETMSSLN 494
Query: 438 KIPLILALSNPTSQSECTAEEAYTWSEGRAIFASGSPFDPVEYKGKTYYSGQSNNAYIFP 497
+ P+ILALSNPTSQSECTAE+AYTWSEGRAIFASGSPF PVEY GK Y SGQ+NNAYIFP
Sbjct: 495 EKPIILALSNPTSQSECTAEQAYTWSEGRAIFASGSPFKPVEYNGKLYVSGQANNAYIFP 554
Query: 498 GFGLGIVMSGAIRVHDDMLLAASEALAKQVTEENYKKGLTYPPFSDIRKISANIAANVAA 557
GFGLG+++SGAIRVHDDMLLAASEA A+QVT+E++ KGL +PPF+ IRKISA+IAA VAA
Sbjct: 555 GFGLGLIISGAIRVHDDMLLAASEAPAEQVTQEHFDKGLIFPPFTSIRKISAHIAAKVAA 614
Query: 558 KAYEL 562
KAYEL
Sbjct: 615 KAYEL 619
>MAOC_ORYSA (P43279) NADP-dependent malic enzyme, chloroplast
precursor (EC 1.1.1.40) (NADP-ME)
Length = 638
Score = 897 bits (2317), Expect = 0.0
Identities = 434/542 (80%), Positives = 498/542 (91%), Gaps = 5/542 (0%)
Query: 21 SAVGGGVEDVYGEDCATEDQLVTPWTFSVASGYSLLRDPQYNKGLAFTEKERDAHYLRGL 80
+A GGGVED+ ATE+ VTPW FSVASGY+LLRDP +NKGLAF+EKERDAHYLRGL
Sbjct: 73 AAAGGGVEDM-----ATEEVPVTPWAFSVASGYTLLRDPHHNKGLAFSEKERDAHYLRGL 127
Query: 81 LPPTVSSQQLQEKKLMHNIRQYEVPLQKYVAMMDLQERNERLFYKLLIDNVEELLPIVYT 140
LPP V SQ LQ KK+MHN+RQY VPLQ+Y+AMMDLQERNERLFYKLLIDNVEELLP+VYT
Sbjct: 128 LPPAVVSQDLQVKKIMHNLRQYSVPLQRYMAMMDLQERNERLFYKLLIDNVEELLPVVYT 187
Query: 141 PVVGEACQKYGSIYKRPQGLYISLKEKGKILEVLKNWPERSIQVIVVTDGERILGLGDLG 200
P VGEACQKYGSI+++PQGLY+SLK+KGK+L+VL+NWPER+IQVIVVTDGERILGLGDLG
Sbjct: 188 PTVGEACQKYGSIFRQPQGLYVSLKDKGKVLDVLRNWPERNIQVIVVTDGERILGLGDLG 247
Query: 201 CQGMGIPVGKLALYSALGGVRPSACLPVTIDVGTNNEKLLNDEFYIGLRQKRATGKEYYD 260
CQGMGIPVGKL+LY+ALGGVRPSACLP+TIDVGTNNE+LLNDEFYIGLRQ+RATGKEY++
Sbjct: 248 CQGMGIPVGKLSLYTALGGVRPSACLPITIDVGTNNEQLLNDEFYIGLRQRRATGKEYHE 307
Query: 261 LLHEFMTAVKQNYGEKVLVQFEDFANHNAFELLAKYGTTHLVFNDDIQGTAAVVLAGVVA 320
L+ EFM+AVKQ YGEKVL+QFEDFANHNAF+LLAKY +HLVFNDDIQGTA+VVLAG+++
Sbjct: 308 LMEEFMSAVKQIYGEKVLIQFEDFANHNAFDLLAKYSKSHLVFNDDIQGTASVVLAGLLS 367
Query: 321 SLKLIGGTLPEHTFLFLGAGEAGTGIAELIALEMSKQTKAPIEESRKKIWLVDSKGLIVS 380
SLK++GGTL EHT+LFLGAGEAGTGIAELIALE+SKQTKAPIEE RKK+WL+DSKGLIV+
Sbjct: 368 SLKVVGGTLAEHTYLFLGAGEAGTGIAELIALEISKQTKAPIEECRKKVWLLDSKGLIVN 427
Query: 381 SRANSLQHFKKPWAHEHEPVSTLLDAVKIIKPTVLIGSSGVGKTFTKEVVEAMTEINKIP 440
SR SLQ FKKPWAHEHEPV+TLLDAV+ IKPTVLIG+SGVGKTFTKEV+EAM N+ P
Sbjct: 428 SRKESLQAFKKPWAHEHEPVTTLLDAVQSIKPTVLIGTSGVGKTFTKEVIEAMASFNERP 487
Query: 441 LILALSNPTSQSECTAEEAYTWSEGRAIFASGSPFDPVEYKGKTYYSGQSNNAYIFPGFG 500
+I +L+NPTS SECTAEEAY WS+GRA+FASGSPFDPVEY GK + GQSNNAYIFPGFG
Sbjct: 488 VIFSLANPTSHSECTAEEAYNWSQGRAVFASGSPFDPVEYNGKIHVPGQSNNAYIFPGFG 547
Query: 501 LGIVMSGAIRVHDDMLLAASEALAKQVTEENYKKGLTYPPFSDIRKISANIAANVAAKAY 560
LG+V+SGA+RVH+DMLLAASE LA Q T+EN++KG +PPF++IRKISA IAA VAAKAY
Sbjct: 548 LGVVISGAVRVHEDMLLAASETLADQATQENFEKGSIFPPFTNIRKISARIAATVAAKAY 607
Query: 561 EL 562
EL
Sbjct: 608 EL 609
>MAOC_LYCES (P37222) NADP-dependent malic enzyme, chloroplast (EC
1.1.1.40) (NADP-ME) (Fragment)
Length = 573
Score = 875 bits (2262), Expect = 0.0
Identities = 433/542 (79%), Positives = 487/542 (88%), Gaps = 2/542 (0%)
Query: 21 SAVGGGVEDVYGEDCATEDQLVTPWTFSVASGYSLLRDPQYNKGLAFTEKERDAHYLRGL 80
S V GGV+DVYGED ATEDQ +TPWT SVASG+SLLR+P YNKGLAF+E+ERD HYLRGL
Sbjct: 5 STVTGGVQDVYGEDSATEDQSITPWTLSVASGFSLLRNPHYNKGLAFSERERDTHYLRGL 64
Query: 81 LPPTVSSQQLQEKKLMHNIRQYEVPLQKYVAMMDLQERNERLFYKLLIDNVEELLPIVYT 140
LPP V S LQ KK+M++IR+Y+VPLQ+Y+AMMDLQE NERLFYKLLIDNVEELLPIVYT
Sbjct: 65 LPPVVISHDLQVKKMMNSIRKYDVPLQRYMAMMDLQEMNERLFYKLLIDNVEELLPIVYT 124
Query: 141 PVVGEACQKYGSIYKRPQGLYISLKEKGKILEVLKNWPERSIQVIVVTDGERILGLGDLG 200
P VGEACQKYG I+KRPQGL+ SLKEKGKI EVLKNWPE+ IQVIVVTDGERILGLGDLG
Sbjct: 125 PTVGEACQKYGWIFKRPQGLFFSLKEKGKIHEVLKNWPEKKIQVIVVTDGERILGLGDLG 184
Query: 201 CQGMGIPVGKLALYSALGGVRPSACLPVTIDVGTNNEKLLNDEFYIGLRQKRATGKEYYD 260
CQGMGIPVGKL+LYSALGG+RPSACLPVTIDVG K ++DEFYIGLRQ+RATG+EY +
Sbjct: 185 CQGMGIPVGKLSLYSALGGIRPSACLPVTIDVG-QTMKFVDDEFYIGLRQRRATGQEYSE 243
Query: 261 LLHEFMTAVKQNYGEKVLVQFEDFANHNAFELLAKYGTTHLVFNDDIQGTAAVVLAGVVA 320
LL EFM AVKQNYGEKVL+QFEDFANHNAF LLAKYGT+HLVFNDDIQGTA+VVLAG++A
Sbjct: 244 LLDEFMYAVKQNYGEKVLIQFEDFANHNAFNLLAKYGTSHLVFNDDIQGTASVVLAGLMA 303
Query: 321 SLKLIGGTLPEHTFLFLGAGEAGTGIAELIALEMSKQTKAPIEESRKKIWLVDSKGLIVS 380
+L L+GG+L EHTFLFLGAGEAGTGIAELIALEMSKQT P+EE+RKKIW+VDSKGLIV
Sbjct: 304 ALNLVGGSLSEHTFLFLGAGEAGTGIAELIALEMSKQTGIPLEETRKKIWMVDSKGLIVK 363
Query: 381 SRANSLQHFKKPWAHEHEPVSTLLDAVKIIKPTVLIGSSGVGKTFTKEVVEAMTEINKIP 440
SR LQHFK+PWAH+HEPV L++AVK IKPTVLIGSSG G+TFTKEVV+AM N+ P
Sbjct: 364 SRMEMLQHFKRPWAHDHEPVQELVNAVKSIKPTVLIGSSGAGRTFTKEVVQAMATFNEKP 423
Query: 441 LILALSNPTSQSECTAEEAYTWSEGRAIFASGSPFDPVEYKGKTYYSGQSNNAYIFPGFG 500
+I ALSNPTSQSECTAEEAY+WSEGRAIFASGSPF PVEY GK Y SGQ+NNAYIFPGFG
Sbjct: 424 IIFALSNPTSQSECTAEEAYSWSEGRAIFASGSPFAPVEYNGKVYASGQANNAYIFPGFG 483
Query: 501 LGIVMSGAIRVHDDMLLAASEALAKQVTEENYKKGLTYPPFSDIRKISANIAANVAAKAY 560
LG+++SGAIRVHDDMLL ASEALA +V++EN++KG PPFS+IRKISA+I A VAAKAY
Sbjct: 484 LGLIISGAIRVHDDMLLVASEALADEVSQENFEKGTHIPPFSNIRKISAHI-AKVAAKAY 542
Query: 561 EL 562
EL
Sbjct: 543 EL 544
>MAOC_MAIZE (P16243) NADP-dependent malic enzyme, chloroplast
precursor (EC 1.1.1.40) (NADP-ME)
Length = 636
Score = 839 bits (2168), Expect = 0.0
Identities = 407/527 (77%), Positives = 471/527 (89%)
Query: 36 ATEDQLVTPWTFSVASGYSLLRDPQYNKGLAFTEKERDAHYLRGLLPPTVSSQQLQEKKL 95
A+E+ V PW SVASGY+LLRDP +NKGLAFTE+ERD HYLRGLLPP V SQ+LQ KK
Sbjct: 81 ASEELPVMPWATSVASGYTLLRDPHHNKGLAFTEEERDGHYLRGLLPPAVLSQELQIKKF 140
Query: 96 MHNIRQYEVPLQKYVAMMDLQERNERLFYKLLIDNVEELLPIVYTPVVGEACQKYGSIYK 155
M+ +RQY+ PLQ+Y+AMM+LQE +ERLFYKLLIDNV ELLP VYTP VGEACQKYGSI+
Sbjct: 141 MNTLRQYQTPLQRYIAMMNLQETDERLFYKLLIDNVVELLPFVYTPTVGEACQKYGSIFG 200
Query: 156 RPQGLYISLKEKGKILEVLKNWPERSIQVIVVTDGERILGLGDLGCQGMGIPVGKLALYS 215
RPQGLY+SLK+KGK+LEVL+NWP R+IQVI VTDGERILGLGDLGCQGMGIPVGKLALY+
Sbjct: 201 RPQGLYVSLKDKGKVLEVLRNWPHRNIQVICVTDGERILGLGDLGCQGMGIPVGKLALYT 260
Query: 216 ALGGVRPSACLPVTIDVGTNNEKLLNDEFYIGLRQKRATGKEYYDLLHEFMTAVKQNYGE 275
ALGGV PS CLP+TIDVGTNNE LLNDEFYIGLRQKRATG+EY +L+ EFM+AVKQ YGE
Sbjct: 261 ALGGVDPSVCLPITIDVGTNNEFLLNDEFYIGLRQKRATGEEYDELIEEFMSAVKQFYGE 320
Query: 276 KVLVQFEDFANHNAFELLAKYGTTHLVFNDDIQGTAAVVLAGVVASLKLIGGTLPEHTFL 335
KVL+QFEDFANHNAF+LL KY +HLVFNDDIQGTA+VVLAG++A+LK++GGTL E T+L
Sbjct: 321 KVLIQFEDFANHNAFDLLEKYSKSHLVFNDDIQGTASVVLAGLLAALKMVGGTLAEQTYL 380
Query: 336 FLGAGEAGTGIAELIALEMSKQTKAPIEESRKKIWLVDSKGLIVSSRANSLQHFKKPWAH 395
FLGAGEAGTGIAELIALE+SKQT APIEE RKK+WLVDSKGLIV SR SLQ FKKPWAH
Sbjct: 381 FLGAGEAGTGIAELIALEISKQTNAPIEECRKKVWLVDSKGLIVDSRKGSLQPFKKPWAH 440
Query: 396 EHEPVSTLLDAVKIIKPTVLIGSSGVGKTFTKEVVEAMTEINKIPLILALSNPTSQSECT 455
EHEP+ TL DAV+ IKPTVLIG+SGVG+TFTKE++EAM+ N+ P+I +LSNPTS SECT
Sbjct: 441 EHEPLKTLYDAVQSIKPTVLIGTSGVGRTFTKEIIEAMSSFNERPIIFSLSNPTSHSECT 500
Query: 456 AEEAYTWSEGRAIFASGSPFDPVEYKGKTYYSGQSNNAYIFPGFGLGIVMSGAIRVHDDM 515
AE+AYTWS+GR+IFASGSPF PVEY+GKT+ GQSNNAYIFPG GLG+V+SGA+RVH+DM
Sbjct: 501 AEQAYTWSQGRSIFASGSPFAPVEYEGKTFVPGQSNNAYIFPGLGLGLVISGAVRVHEDM 560
Query: 516 LLAASEALAKQVTEENYKKGLTYPPFSDIRKISANIAANVAAKAYEL 562
LLAAS+ALA Q T++N++KG +PPF+ IRKISA+IAA VA KAYEL
Sbjct: 561 LLAASKALADQATQDNFEKGSIFPPFTSIRKISAHIAAAVAGKAYEL 607
>MAOX_ANAPL (P28227) NADP-dependent malic enzyme (EC 1.1.1.40)
(NADP-ME)
Length = 557
Score = 555 bits (1430), Expect = e-157
Identities = 278/510 (54%), Positives = 359/510 (69%), Gaps = 3/510 (0%)
Query: 52 GYSLLRDPQYNKGLAFTEKERDAHYLRGLLPPTVSSQQLQEKKLMHNIRQYEVPLQKYVA 111
GY +LRDP NKG+AFT +ER + GLLPP Q +Q ++ N + L +Y+
Sbjct: 4 GYEVLRDPHLNKGMAFTLEERQQLNIHGLLPPCFLGQDVQVFSILKNFERLTSDLDRYIL 63
Query: 112 MMDLQERNERLFYKLLIDNVEELLPIVYTPVVGEACQKYGSIYKRPQGLYISLKEKGKIL 171
+M LQ+RNE+LFYK+L ++E +PIVYTP VG ACQ+YG ++RP+GL+I++ ++G I
Sbjct: 64 LMSLQDRNEKLFYKVLTSDIERFMPIVYTPTVGLACQQYGLAFRRPRGLFITIHDRGHIA 123
Query: 172 EVLKNWPERSIQVIVVTDGERILGLGDLGCQGMGIPVGKLALYSALGGVRPSACLPVTID 231
+LK+WPE I+ IVVTDGERILGLGDLGC GMGIPVGKLALY+A GGV+P CLPV +D
Sbjct: 124 TMLKSWPESVIKAIVVTDGERILGLGDLGCYGMGIPVGKLALYTACGGVKPHECLPVMLD 183
Query: 232 VGTNNEKLLNDEFYIGLRQKRATGKEYYDLLHEFMTAVKQNYGEKVLVQFEDFANHNAFE 291
VGT+NE LL D YIGLR KR G+ Y DLL EFM AV YG L+QFEDFAN NAF
Sbjct: 184 VGTDNEALLKDPLYIGLRHKRIRGQAYDDLLDEFMEAVTSRYGMNCLIQFEDFANANAFR 243
Query: 292 LLAKYGTTHLVFNDDIQGTAAVVLAGVVASLKLIGGTLPEHTFLFLGAGEAGTGIAELIA 351
LL KY + FNDDIQGTA+V +AG++A+L++ L +HT LF GAGEA GIA LI
Sbjct: 244 LLHKYRNKYCTFNDDIQGTASVAVAGLLAALRITKNRLSDHTVLFQGAGEAALGIANLIV 303
Query: 352 LEMSKQTKAPIEESRKKIWLVDSKGLIVSSRANSLQHFKKPWAHEHEPVSTLLDAVKIIK 411
+ M K+ + E + K+IW+VDSKGLIV RA SL K +AHEH + L D VK IK
Sbjct: 304 MAMEKEGVSK-EAAVKRIWMVDSKGLIVKGRA-SLTAEKTRFAHEHAEMKNLEDIVKDIK 361
Query: 412 PTVLIGSSGVGKTFTKEVVEAMTEINKIPLILALSNPTSQSECTAEEAYTWSEGRAIFAS 471
P+VLIG + +G FTKE+++ M NK P+I ALSNPTS++ECTAE+ Y ++EGR IFAS
Sbjct: 362 PSVLIGVAAIGGAFTKEILQDMAAFNKRPIIFALSNPTSKAECTAEQCYKYTEGRGIFAS 421
Query: 472 GSPFDPVEY-KGKTYYSGQSNNAYIFPGFGLGIVMSGAIRVHDDMLLAASEALAKQVTEE 530
GSPFDPV GKT Y GQ NN+Y+FPG LG++ G + +D+ L +E +A+QV+EE
Sbjct: 422 GSPFDPVTLPNGKTLYPGQGNNSYVFPGVALGVIACGLKHIGEDVFLTTAEVIAEQVSEE 481
Query: 531 NYKKGLTYPPFSDIRKISANIAANVAAKAY 560
N ++G YPP I+ +S IA +A +AY
Sbjct: 482 NLQEGRLYPPLVTIQHVSLKIAVRIAEEAY 511
>MAOX_COLLI (P40927) NADP-dependent malic enzyme (EC 1.1.1.40)
(NADP-ME)
Length = 557
Score = 552 bits (1423), Expect = e-157
Identities = 276/510 (54%), Positives = 360/510 (70%), Gaps = 3/510 (0%)
Query: 52 GYSLLRDPQYNKGLAFTEKERDAHYLRGLLPPTVSSQQLQEKKLMHNIRQYEVPLQKYVA 111
GY +LRDP NKG+AFT +ER + GLLPP Q Q ++ N + L +Y+
Sbjct: 4 GYEVLRDPHLNKGMAFTLEERQQLNIHGLLPPCFLGQDAQVYSILKNFERLTSDLDRYIL 63
Query: 112 MMDLQERNERLFYKLLIDNVEELLPIVYTPVVGEACQKYGSIYKRPQGLYISLKEKGKIL 171
+M LQ+RNE+LFYK+L ++E +PIVYTP VG ACQ YG ++RP+GL+I++ ++G I
Sbjct: 64 LMSLQDRNEKLFYKVLTSDIERFMPIVYTPTVGLACQHYGLAFRRPRGLFITIHDRGHIA 123
Query: 172 EVLKNWPERSIQVIVVTDGERILGLGDLGCQGMGIPVGKLALYSALGGVRPSACLPVTID 231
+L++WPE I+ IVVTDGERILGLGDLGC GMGIPVGKLALY+A GGV+P CLPV +D
Sbjct: 124 TMLQSWPESVIKAIVVTDGERILGLGDLGCYGMGIPVGKLALYTACGGVKPHQCLPVMLD 183
Query: 232 VGTNNEKLLNDEFYIGLRQKRATGKEYYDLLHEFMTAVKQNYGEKVLVQFEDFANHNAFE 291
VGT+NE LL D YIGLR KR G+ Y DLL EFM AV YG L+QFEDFAN NAF
Sbjct: 184 VGTDNETLLKDPLYIGLRHKRIRGQAYDDLLDEFMEAVTSRYGMNCLIQFEDFANANAFR 243
Query: 292 LLAKYGTTHLVFNDDIQGTAAVVLAGVVASLKLIGGTLPEHTFLFLGAGEAGTGIAELIA 351
LL KY + FNDDIQGTA+V +AG++A+L++ L +HT LF GAGEA GIA LI
Sbjct: 244 LLHKYRNKYCTFNDDIQGTASVAVAGLLAALRITKNRLSDHTVLFQGAGEAALGIANLIV 303
Query: 352 LEMSKQTKAPIEESRKKIWLVDSKGLIVSSRANSLQHFKKPWAHEHEPVSTLLDAVKIIK 411
+ M K+ + EE+ K+IW+VDSKGLIV RA SL K+ +AHEH + L D VK IK
Sbjct: 304 MAMQKEGVSK-EEAIKRIWMVDSKGLIVKGRA-SLTPEKEHFAHEHCEMKNLEDIVKDIK 361
Query: 412 PTVLIGSSGVGKTFTKEVVEAMTEINKIPLILALSNPTSQSECTAEEAYTWSEGRAIFAS 471
PTVLIG + +G FT+++++ M NK P+I ALSNPTS++ECTAE+ Y ++EGR IFAS
Sbjct: 362 PTVLIGVAAIGGAFTQQILQDMAAFNKRPIIFALSNPTSKAECTAEQLYKYTEGRGIFAS 421
Query: 472 GSPFDPVEY-KGKTYYSGQSNNAYIFPGFGLGIVMSGAIRVHDDMLLAASEALAKQVTEE 530
GSPFDPV G+T Y GQ NN+Y+FPG LG++ G + DD+ L +E +A++V+EE
Sbjct: 422 GSPFDPVTLPSGQTLYPGQGNNSYVFPGVALGVISCGLKHIGDDVFLTTAEVIAQEVSEE 481
Query: 531 NYKKGLTYPPFSDIRKISANIAANVAAKAY 560
N ++G YPP I+++S IA +A +AY
Sbjct: 482 NLQEGRLYPPLVTIQQVSLKIAVRIAKEAY 511
>MAOX_HUMAN (P48163) NADP-dependent malic enzyme (EC 1.1.1.40)
(NADP-ME) (Malic enzyme 1)
Length = 572
Score = 538 bits (1387), Expect = e-152
Identities = 274/533 (51%), Positives = 371/533 (69%), Gaps = 7/533 (1%)
Query: 52 GYSLLRDPQYNKGLAFTEKERDAHYLRGLLPPTVSSQQLQEKKLMHNIRQYEVPLQKYVA 111
GY L R+P NK LAFT +ER + GLLPP+ +SQ++Q +++ N +Y+
Sbjct: 15 GYLLTRNPHLNKDLAFTLEERQQLNIHGLLPPSFNSQEIQVLRVVKNFEHLNSDFDRYLL 74
Query: 112 MMDLQERNERLFYKLLIDNVEELLPIVYTPVVGEACQKYGSIYKRPQGLYISLKEKGKIL 171
+MDLQ+RNE+LFY++L ++E+ +PIVYTP VG ACQ+Y ++++P+GL+I++ ++G I
Sbjct: 75 LMDLQDRNEKLFYRVLTSDIEKFMPIVYTPTVGLACQQYSLVFRKPRGLFITIHDRGHIA 134
Query: 172 EVLKNWPERSIQVIVVTDGERILGLGDLGCQGMGIPVGKLALYSALGGVRPSACLPVTID 231
VL WPE I+ IVVTDGERILGLGDLGC GMGIPVGKLALY+A GG+ P CLPV +D
Sbjct: 135 SVLNAWPEDVIKAIVVTDGERILGLGDLGCNGMGIPVGKLALYTACGGMNPQECLPVILD 194
Query: 232 VGTNNEKLLNDEFYIGLRQKRATGKEYYDLLHEFMTAVKQNYGEKVLVQFEDFANHNAFE 291
VGT NE+LL D YIGLRQ+R G EY D L EFM AV YG L+QFEDFAN NAF
Sbjct: 195 VGTENEELLKDPLYIGLRQRRVRGSEYDDFLDEFMEAVSSKYGMNCLIQFEDFANVNAFR 254
Query: 292 LLAKYGTTHLVFNDDIQGTAAVVLAGVVASLKLIGGTLPEHTFLFLGAGEAGTGIAELIA 351
LL KY + FNDDIQGTA+V +AG++A+L++ L + T LF GAGEA GIA LI
Sbjct: 255 LLNKYRNQYCTFNDDIQGTASVAVAGLLAALRITKNKLSDQTILFQGAGEAALGIAHLIV 314
Query: 352 LEMSKQTKAPIEESRKKIWLVDSKGLIVSSRANSLQHFKKPWAHEHEPVSTLLDAVKIIK 411
+ + K+ P E++ KKIWLVDSKGLIV RA SL K+ +AHEHE + L V+ IK
Sbjct: 315 MALEKE-GLPKEKAIKKIWLVDSKGLIVKGRA-SLTQEKEKFAHEHEEMKNLEAIVQEIK 372
Query: 412 PTVLIGSSGVGKTFTKEVVEAMTEINKIPLILALSNPTSQSECTAEEAYTWSEGRAIFAS 471
PT LIG + +G F++++++ M N+ P+I ALSNPTS++EC+AE+ Y ++GRAIFAS
Sbjct: 373 PTALIGVAAIGGAFSEQILKDMAAFNERPIIFALSNPTSKAECSAEQCYKITKGRAIFAS 432
Query: 472 GSPFDPVEY-KGKTYYSGQSNNAYIFPGFGLGIVMSGAIRVHDDMLLAASEALAKQVTEE 530
GSPFDPV G+T Y GQ NN+Y+FPG LG+V G ++ D++ L +E +A+QV+++
Sbjct: 433 GSPFDPVTLPNGQTLYPGQGNNSYVFPGVALGVVACGLRQITDNIFLTTAEVIAQQVSDK 492
Query: 531 NYKKGLTYPPFSDIRKISANIAANVAAKAYELVCTATIGEQGQFTIDSEAFGR 583
+ ++G YPP + IR +S IA + AY+ TAT+ + Q + EAF R
Sbjct: 493 HLEEGRLYPPLNTIRDVSLKIAEKIVKDAYQ-EKTATVYPEPQ---NKEAFVR 541
>MAOX_PIG (Q29558) NADP-dependent malic enzyme (EC 1.1.1.40)
(NADP-ME) (Malic enzyme 1) (Fragment)
Length = 557
Score = 538 bits (1385), Expect = e-152
Identities = 272/518 (52%), Positives = 359/518 (68%), Gaps = 4/518 (0%)
Query: 52 GYSLLRDPQYNKGLAFTEKERDAHYLRGLLPPTVSSQQLQEKKLMHNIRQYEVPLQKYVA 111
GY L R P NK LAFT +ER + GLLPP SQ +Q +++ N + +Y+
Sbjct: 1 GYGLTRIPHLNKDLAFTLEERQQLNIHGLLPPCFISQDIQVLRVIKNFERLNSDFDRYLL 60
Query: 112 MMDLQERNERLFYKLLIDNVEELLPIVYTPVVGEACQKYGSIYKRPQGLYISLKEKGKIL 171
+MDLQ+RNE+LFYK+L+ ++E+ +PIVYTP VG ACQ+Y +++P+GL+IS+ ++G +
Sbjct: 61 LMDLQDRNEKLFYKVLMSDIEKFMPIVYTPTVGLACQQYSLAFRKPRGLFISIHDRGHVA 120
Query: 172 EVLKNWPERSIQVIVVTDGERILGLGDLGCQGMGIPVGKLALYSALGGVRPSACLPVTID 231
VL WPE I+ +VVTDGERILGLGDLGC GMGIPVGKLALY+A GGV P CLPV +D
Sbjct: 121 SVLNAWPEDVIKAVVVTDGERILGLGDLGCNGMGIPVGKLALYTACGGVNPQECLPVILD 180
Query: 232 VGTNNEKLLNDEFYIGLRQKRATGKEYYDLLHEFMTAVKQNYGEKVLVQFEDFANHNAFE 291
VGT NE+LL D YIGLRQ+R G EY D L EFM AV YG L+QFEDFAN NAF
Sbjct: 181 VGTENEELLKDPLYIGLRQRRVRGPEYDDFLDEFMEAVSSKYGMNCLIQFEDFANINAFR 240
Query: 292 LLAKYGTTHLVFNDDIQGTAAVVLAGVVASLKLIGGTLPEHTFLFLGAGEAGTGIAELIA 351
LL KY + FNDDIQGTA+V +AG++A+L++ L + T LF GAGEA GIA LI
Sbjct: 241 LLKKYQNQYCTFNDDIQGTASVAVAGILAALRITKNKLSDQTILFQGAGEAALGIAHLIV 300
Query: 352 LEMSKQTKAPIEESRKKIWLVDSKGLIVSSRANSLQHFKKPWAHEHEPVSTLLDAVKIIK 411
+ M K+ P E++ KKIWLVDSKGLIV RA +L + K+ +AHEHE + L V+ IK
Sbjct: 301 MAMEKE-GVPKEKAIKKIWLVDSKGLIVKGRA-ALTNEKEEFAHEHEEMKNLEAIVQDIK 358
Query: 412 PTVLIGSSGVGKTFTKEVVEAMTEINKIPLILALSNPTSQSECTAEEAYTWSEGRAIFAS 471
PT LIG + +G F++++++ M N+ P+I ALSNPTS++ECTAE YT ++GRAIFAS
Sbjct: 359 PTALIGVAAIGGAFSEQILKDMAAFNERPIIFALSNPTSKAECTAERGYTLTQGRAIFAS 418
Query: 472 GSPFDPVEY-KGKTYYSGQSNNAYIFPGFGLGIVMSGAIRVHDDMLLAASEALAKQVTEE 530
GSPFDPV G+T Y GQ NN+Y+FPG L +V G + D + L +E +A+QV+++
Sbjct: 419 GSPFDPVTLPSGQTLYPGQGNNSYVFPGVALAVVACGLRHITDKIFLTTAEVIAQQVSDK 478
Query: 531 NYKKGLTYPPFSDIRKISANIAANVAAKAYELVCTATI 568
+ ++G YPP + IR +S IA + AY+ TATI
Sbjct: 479 HLEEGRLYPPLNTIRDVSLKIAEKIVRDAYQ-EKTATI 515
>MAOX_RAT (P13697) NADP-dependent malic enzyme (EC 1.1.1.40)
(NADP-ME) (Malic enzyme 1)
Length = 572
Score = 536 bits (1382), Expect = e-152
Identities = 267/511 (52%), Positives = 357/511 (69%), Gaps = 3/511 (0%)
Query: 52 GYSLLRDPQYNKGLAFTEKERDAHYLRGLLPPTVSSQQLQEKKLMHNIRQYEVPLQKYVA 111
GY L RDP NK LAFT +ER + GLLPP + +Q++Q +++ N + +Y+
Sbjct: 15 GYLLTRDPHLNKDLAFTLEERQQLKIHGLLPPCIVNQEIQVLRVIKNFERLNSDFDRYLL 74
Query: 112 MMDLQERNERLFYKLLIDNVEELLPIVYTPVVGEACQKYGSIYKRPQGLYISLKEKGKIL 171
+MDLQ+RNE+LFY +L+ NVE+ +PIVYTP VG ACQ+Y +++P+GL+IS+ +KG I
Sbjct: 75 LMDLQDRNEKLFYSVLMSNVEKFMPIVYTPTVGLACQQYSLAFRKPRGLFISIHDKGHIA 134
Query: 172 EVLKNWPERSIQVIVVTDGERILGLGDLGCQGMGIPVGKLALYSALGGVRPSACLPVTID 231
VL WPE ++ IVVTDGERILGLGDLGC GMGIPVGKLALY+A GGV P CLP+T+D
Sbjct: 135 SVLNAWPEDVVKAIVVTDGERILGLGDLGCNGMGIPVGKLALYTACGGVNPQQCLPITLD 194
Query: 232 VGTNNEKLLNDEFYIGLRQKRATGKEYYDLLHEFMTAVKQNYGEKVLVQFEDFANHNAFE 291
VGT NE+LL D YIGLR +R G EY L EFM A YG L+QFEDFAN NAF
Sbjct: 195 VGTENEELLKDPLYIGLRHRRVRGPEYDAFLDEFMEAASSKYGMNCLIQFEDFANLNAFR 254
Query: 292 LLAKYGTTHLVFNDDIQGTAAVVLAGVVASLKLIGGTLPEHTFLFLGAGEAGTGIAELIA 351
LL KY + FNDDIQGTA+V +AG++A+L++ L + T LF GAGEA GIA LI
Sbjct: 255 LLNKYRNKYCTFNDDIQGTASVAVAGLLAALRITKNKLSDQTVLFQGAGEAALGIAHLIV 314
Query: 352 LEMSKQTKAPIEESRKKIWLVDSKGLIVSSRANSLQHFKKPWAHEHEPVSTLLDAVKIIK 411
+ M K+ + E++R+KIWLVDSKGLIV RA SL K+ +AHEHE + L V+ IK
Sbjct: 315 MAMEKEGLSK-EKARQKIWLVDSKGLIVKGRA-SLTEEKEVFAHEHEEMKNLEAIVQKIK 372
Query: 412 PTVLIGSSGVGKTFTKEVVEAMTEINKIPLILALSNPTSQSECTAEEAYTWSEGRAIFAS 471
PT LIG + +G FT+++++ M N+ P+I ALSNPTS++EC+AEE Y ++GRAIFAS
Sbjct: 373 PTALIGVAAIGGAFTEQILKDMAAFNERPIIFALSNPTSKAECSAEECYKVTKGRAIFAS 432
Query: 472 GSPFDPVEY-KGKTYYSGQSNNAYIFPGFGLGIVMSGAIRVHDDMLLAASEALAKQVTEE 530
GSPFDPV G+T + GQ NN+Y+FPG LG+V G ++D + L +E +++QV+++
Sbjct: 433 GSPFDPVTLPDGRTLFPGQGNNSYVFPGVALGVVACGLRHINDSVFLTTAEVISQQVSDK 492
Query: 531 NYKKGLTYPPFSDIRKISANIAANVAAKAYE 561
+ ++G YPP + IR +S IA + AY+
Sbjct: 493 HLEEGRLYPPLNTIRDVSLKIAVKIVQDAYK 523
>MAOX_MOUSE (P06801) NADP-dependent malic enzyme (EC 1.1.1.40)
(NADP-ME) (Malic enzyme 1)
Length = 572
Score = 533 bits (1374), Expect = e-151
Identities = 266/511 (52%), Positives = 354/511 (69%), Gaps = 3/511 (0%)
Query: 52 GYSLLRDPQYNKGLAFTEKERDAHYLRGLLPPTVSSQQLQEKKLMHNIRQYEVPLQKYVA 111
GY L RDP NK LAFT +ER + GLLPP + SQ+LQ +++ N + +Y+
Sbjct: 15 GYLLTRDPHLNKDLAFTLEERQQLNIHGLLPPCIISQELQVLRIIKNFERLNSDFDRYLL 74
Query: 112 MMDLQERNERLFYKLLIDNVEELLPIVYTPVVGEACQKYGSIYKRPQGLYISLKEKGKIL 171
+MDLQ+RNE+LFY +L+ +VE+ +PIVYTP VG ACQ+Y +++P+GL+IS+ +KG I
Sbjct: 75 LMDLQDRNEKLFYSVLMSDVEKFMPIVYTPTVGLACQQYSLAFRKPRGLFISIHDKGHIA 134
Query: 172 EVLKNWPERSIQVIVVTDGERILGLGDLGCQGMGIPVGKLALYSALGGVRPSACLPVTID 231
VL WPE ++ IVVTDGERILGLGDLGC GMGIPVGKLALY+A GGV P CLP+T+D
Sbjct: 135 SVLNAWPEDVVKAIVVTDGERILGLGDLGCNGMGIPVGKLALYTACGGVNPQQCLPITLD 194
Query: 232 VGTNNEKLLNDEFYIGLRQKRATGKEYYDLLHEFMTAVKQNYGEKVLVQFEDFANHNAFE 291
VGT NE+LL D YIGLR +R G EY L EFM A YG L+QFEDFAN NAF
Sbjct: 195 VGTENEELLKDPLYIGLRHRRVRGPEYDAFLDEFMEAASSKYGMNCLIQFEDFANRNAFR 254
Query: 292 LLAKYGTTHLVFNDDIQGTAAVVLAGVVASLKLIGGTLPEHTFLFLGAGEAGTGIAELIA 351
LL KY + FNDDIQGTA+V +AG++A+L++ L + T LF GAGEA GIA L+
Sbjct: 255 LLNKYRNKYCTFNDDIQGTASVAVAGLLAALRITKNKLSDQTVLFQGAGEAALGIAHLVV 314
Query: 352 LEMSKQTKAPIEESRKKIWLVDSKGLIVSSRANSLQHFKKPWAHEHEPVSTLLDAVKIIK 411
+ M K+ + E +RKKIWLVDSKGLIV RA SL K+ +AHEHE + L V+ IK
Sbjct: 315 MAMEKEGLSK-ENARKKIWLVDSKGLIVKGRA-SLTEEKEVFAHEHEEMKNLEAIVQKIK 372
Query: 412 PTVLIGSSGVGKTFTKEVVEAMTEINKIPLILALSNPTSQSECTAEEAYTWSEGRAIFAS 471
PT LIG + +G FT+++++ M N+ P+I ALS+PTS++EC+A+E Y ++GRAIFAS
Sbjct: 373 PTALIGVAAIGGAFTEQILKDMAAFNERPIIFALSSPTSKAECSADECYKVTKGRAIFAS 432
Query: 472 GSPFDPVEY-KGKTYYSGQSNNAYIFPGFGLGIVMSGAIRVHDDMLLAASEALAKQVTEE 530
GSPFDPV G+T + GQ NN+Y+FPG LG+V G + D + L E +++QV+++
Sbjct: 433 GSPFDPVTLPDGRTLFPGQGNNSYVFPGVALGVVACGLRHIDDKVFLTTREVISQQVSDK 492
Query: 531 NYKKGLTYPPFSDIRKISANIAANVAAKAYE 561
+ ++G YPP + IR +S IA + AY+
Sbjct: 493 HLQEGRLYPPLNTIRGVSLKIAVKIVQDAYK 523
>MAOM_HUMAN (P23368) NAD-dependent malic enzyme, mitochondrial
precursor (EC 1.1.1.38) (NAD-ME) (Malic enzyme 2)
Length = 584
Score = 530 bits (1364), Expect = e-150
Identities = 257/512 (50%), Positives = 353/512 (68%), Gaps = 4/512 (0%)
Query: 52 GYSLLRDPQYNKGLAFTEKERDAHYLRGLLPPTVSSQQLQEKKLMHNIRQYEVPLQKYVA 111
G L+ +P+ NKG+AFT +ER L+GLLPP + +Q +Q + N+++ PL+KY+
Sbjct: 25 GKPLMLNPRTNKGMAFTLQERQMLGLQGLLPPKIETQDIQALRFHRNLKKMTSPLEKYIY 84
Query: 112 MMDLQERNERLFYKLLIDNVEELLPIVYTPVVGEACQKYGSIYKRPQGLYISLKEKGKIL 171
+M +QERNE+LFY++L D++E L+PIVYTP VG AC +YG I++RP+GL+IS+ ++G +
Sbjct: 85 IMGIQERNEKLFYRILQDDIESLMPIVYTPTVGLACSQYGHIFRRPKGLFISISDRGHVR 144
Query: 172 EVLKNWPERSIQVIVVTDGERILGLGDLGCQGMGIPVGKLALYSALGGVRPSACLPVTID 231
++ NWPE ++ +VVTDGERILGLGDLG GMGIPVGKL LY+A G+RP CLPV ID
Sbjct: 145 SIVDNWPENHVKAVVVTDGERILGLGDLGVYGMGIPVGKLCLYTACAGIRPDRCLPVCID 204
Query: 232 VGTNNEKLLNDEFYIGLRQKRATGKEYYDLLHEFMTAVKQNYGEKVLVQFEDFANHNAFE 291
VGT+N LL D FY+GL QKR ++Y DL+ EFM A+ YG L+QFEDF NHNAF
Sbjct: 205 VGTDNIALLKDPFYMGLYQKRDRTQQYDDLIDEFMKAITDRYGRNTLIQFEDFGNHNAFR 264
Query: 292 LLAKYGTTHLVFNDDIQGTAAVVLAGVVASLKLIGGTLPEHTFLFLGAGEAGTGIAELIA 351
L KY + FNDDIQGTAAV LAG++A+ K+I + EH LFLGAGEA GIA LI
Sbjct: 265 FLRKYREKYCTFNDDIQGTAAVALAGLLAAQKVISKPISEHKILFLGAGEAALGIANLIV 324
Query: 352 LEMSKQTKAPIEESRKKIWLVDSKGLIVSSRANSLQHFKKPWAHE--HEPVSTLLDAVKI 409
+ M + + +E++KKIW+ D GL+V R + +++P+ H T DAV I
Sbjct: 325 MSMVENGLSE-QEAQKKIWMFDKYGLLVKGRKAKIDSYQEPFTHSAPESIPDTFEDAVNI 383
Query: 410 IKPTVLIGSSGVGKTFTKEVVEAMTEINKIPLILALSNPTSQSECTAEEAYTWSEGRAIF 469
+KP+ +IG +G G+ FT +V+ AM IN+ P+I ALSNPT+Q+ECTAEEAYT +EGR +F
Sbjct: 384 LKPSTIIGVAGAGRLFTPDVIRAMASINERPVIFALSNPTAQAECTAEEAYTLTEGRCLF 443
Query: 470 ASGSPFDPVEY-KGKTYYSGQSNNAYIFPGFGLGIVMSGAIRVHDDMLLAASEALAKQVT 528
ASGSPF PV+ G+ + GQ NN YIFPG L +++ + D + L A++AL Q+T
Sbjct: 444 ASGSPFGPVKLTDGRVFTPGQGNNVYIFPGVALAVILCNTRHISDSVFLEAAKALTSQLT 503
Query: 529 EENYKKGLTYPPFSDIRKISANIAANVAAKAY 560
+E +G YPP ++I+++S NIA V Y
Sbjct: 504 DEELAQGRLYPPLANIQEVSINIAIKVTEYLY 535
>MAON_HUMAN (Q16798) NADP-dependent malic enzyme, mitochondrial
precursor (EC 1.1.1.40) (NADP-ME) (Malic enzyme 3)
Length = 604
Score = 527 bits (1358), Expect = e-149
Identities = 258/511 (50%), Positives = 358/511 (69%), Gaps = 3/511 (0%)
Query: 52 GYSLLRDPQYNKGLAFTEKERDAHYLRGLLPPTVSSQQLQEKKLMHNIRQYEVPLQKYVA 111
GY + R+P NKG+AFT +ER + GL+PP SQ +Q ++M + + L KY+
Sbjct: 50 GYDVTRNPHLNKGMAFTLEERLQLGIHGLIPPCFLSQDVQLLRIMRYYERQQSDLDKYII 109
Query: 112 MMDLQERNERLFYKLLIDNVEELLPIVYTPVVGEACQKYGSIYKRPQGLYISLKEKGKIL 171
+M LQ+RNE+LFY++L +VE+ +PIVYTP VG ACQ YG ++RP+GL+I++ +KG +
Sbjct: 110 LMTLQDRNEKLFYRVLTSDVEKFMPIVYTPTVGLACQHYGLTFRRPRGLFITIHDKGHLA 169
Query: 172 EVLKNWPERSIQVIVVTDGERILGLGDLGCQGMGIPVGKLALYSALGGVRPSACLPVTID 231
+L +WPE +I+ +VVTDGERILGLGDLGC GMGIPVGKLALY+A GGV P CLPV +D
Sbjct: 170 TMLNSWPEDNIKAVVVTDGERILGLGDLGCYGMGIPVGKLALYTACGGVNPQQCLPVLLD 229
Query: 232 VGTNNEKLLNDEFYIGLRQKRATGKEYYDLLHEFMTAVKQNYGEKVLVQFEDFANHNAFE 291
VGTNNE+LL D YIGL+ +R GK Y DLL EFM AV +G L+QFEDFAN NAF
Sbjct: 230 VGTNNEELLRDPLYIGLKHQRVHGKAYDDLLDEFMQAVTDKFGINCLIQFEDFANANAFR 289
Query: 292 LLAKYGTTHLVFNDDIQGTAAVVLAGVVASLKLIGGTLPEHTFLFLGAGEAGTGIAELIA 351
LL KY + +FNDDIQGTA+V +AG++A+L++ L H F+F GAGEA GIA L+
Sbjct: 290 LLNKYRNKYCMFNDDIQGTASVAVAGILAALRITNNKLSNHVFVFQGAGEAAMGIAHLLV 349
Query: 352 LEMSKQTKAPIEESRKKIWLVDSKGLIVSSRANSLQHFKKPWAHEHEPVSTLLDAVKIIK 411
+ + K+ P E+ +KIW+VDSKGLIV R++ L H K+ +A +H V++L + V+++K
Sbjct: 350 MALEKE-GVPKAEATRKIWMVDSKGLIVKGRSH-LNHEKEMFAQDHPEVNSLEEVVRLVK 407
Query: 412 PTVLIGSSGVGKTFTKEVVEAMTEINKIPLILALSNPTSQSECTAEEAYTWSEGRAIFAS 471
PT +IG + + FT++++ M ++ P+I ALSNPTS++ECTAE+ Y +EGR IFAS
Sbjct: 408 PTAIIGVAAIAGAFTEQILRDMASFHERPIIFALSNPTSKAECTAEKCYRVTEGRGIFAS 467
Query: 472 GSPFDPVEYK-GKTYYSGQSNNAYIFPGFGLGIVMSGAIRVHDDMLLAASEALAKQVTEE 530
GSPF V + GKT+ GQ NNAY+FPG LG++ G + D++ L +E +A++V+E+
Sbjct: 468 GSPFKSVTLEDGKTFIPGQGNNAYVFPGVALGVIAGGIRHIPDEIFLLTAEQIAQEVSEQ 527
Query: 531 NYKKGLTYPPFSDIRKISANIAANVAAKAYE 561
+ +G YPP S IR +S IA V AY+
Sbjct: 528 HLSQGRLYPPLSTIRDVSLRIAIKVLDYAYK 558
>MAOM_MOUSE (Q99KE1) NAD-dependent malic enzyme, mitochondrial
precursor (EC 1.1.1.38) (NAD-ME) (Malic enzyme 2)
Length = 589
Score = 523 bits (1347), Expect = e-148
Identities = 259/513 (50%), Positives = 359/513 (69%), Gaps = 6/513 (1%)
Query: 52 GYSLLRDPQYNKGLAFTEKERDAHYLRGLLPPTVSSQQLQEKKLMHNIRQYEVPLQKYVA 111
G L+ +P+ NKG+AFT +ER L+GLLPP + +Q +Q + N+++ PL+KY+
Sbjct: 25 GKPLMLNPRTNKGMAFTLQERQMLGLQGLLPPKIETQDIQALRFHRNLKKMTSPLEKYIY 84
Query: 112 MMDLQERNERLFYKLLIDNVEELLPIVYTPVVGEACQKYGSIYKRPQGLYISLKEKGKIL 171
+M +QERNE+LFY++L D++E L+PIVYTP VG AC +YG I++RP+GL+IS+ ++G +
Sbjct: 85 IMGIQERNEKLFYRILQDDIESLMPIVYTPTVGLACCQYGHIFRRPKGLFISISDRGHVR 144
Query: 172 EVLKNWPERSIQVIVVTDGERILGLGDLGCQGMGIPVGKLALYSALGGVRPSACLPVTID 231
++ NWPE ++ +VVTDGERILGLGDLG GMGIPVGKL LY+A G++P CLPV ID
Sbjct: 145 SIVDNWPENHVKAVVVTDGERILGLGDLGVYGMGIPVGKLCLYTACAGIQPEKCLPVCID 204
Query: 232 VGTNNEKLLNDEFYIGLRQKRATGKEYYDLLHEFMTAVKQNYGEKVLVQFEDFANHNAFE 291
VGT+N LL D FY+GL QKR + Y DL+ EFM A+ YG L+QFEDF NHNAF
Sbjct: 205 VGTDNMALLKDPFYMGLYQKRDRSQLYDDLMDEFMKAITDRYGRNTLIQFEDFGNHNAFR 264
Query: 292 LLAKYGTTHLVFNDDIQGTAAVVLAGVVASLKLIGGTLPEHTFLFLGAGEAGTGIAELIA 351
L KY + FNDDIQGTAAV L+G++A+ ++I + EH LFLGAGEA GIA LI
Sbjct: 265 FLRKYQQKYCTFNDDIQGTAAVALSGLLAAQRVINKPVSEHKILFLGAGEAALGIANLIV 324
Query: 352 LEMSKQTKAPIEESRKKIWLVDSKGLIVSSRANSLQHFKKPWAH---EHEPVSTLLDAVK 408
L M + + EE+++KIW+ D GL+V R S+ ++P+AH E P +T DAV
Sbjct: 325 LSMVESGLSE-EEAQRKIWMFDKSGLLVKGRTASIDSNQEPYAHAAPESIP-ATFEDAVN 382
Query: 409 IIKPTVLIGSSGVGKTFTKEVVEAMTEINKIPLILALSNPTSQSECTAEEAYTWSEGRAI 468
+KP+V+IG +G G FT V++AM IN+ P+I ALSNPT+Q+ECTAE+AYT +EGR +
Sbjct: 383 KLKPSVIIGVAGAGPLFTHGVIKAMASINERPIIFALSNPTAQAECTAEDAYTLTEGRCL 442
Query: 469 FASGSPFDPVEYK-GKTYYSGQSNNAYIFPGFGLGIVMSGAIRVHDDMLLAASEALAKQV 527
FASGSPF+PV+ + G+ + GQ NNAYIFPG L +++ A + D + L A++AL Q+
Sbjct: 443 FASGSPFEPVKLQDGRVFTPGQGNNAYIFPGVALAVILCEARHISDTVFLEAAKALTTQL 502
Query: 528 TEENYKKGLTYPPFSDIRKISANIAANVAAKAY 560
T+ +G YP ++I+++SANIA +A Y
Sbjct: 503 TDAELAQGRLYPSLANIQEVSANIAIKLAEYLY 535
>MAOM_ASCSU (P27443) NAD-dependent malic enzyme, mitochondrial
precursor (EC 1.1.1.38) (NAD-ME) (Fragment)
Length = 643
Score = 488 bits (1257), Expect = e-137
Identities = 249/509 (48%), Positives = 346/509 (67%), Gaps = 4/509 (0%)
Query: 55 LLRDPQYNKGLAFTEKERDAHYLRGLLPPTVSSQQLQEKKLMHNIRQYEVPLQKYVAMMD 114
LL++P+ NKG+ F+ ER L GLLPP +Q+ Q +++ +R+ L +Y+ +
Sbjct: 80 LLKEPRLNKGMGFSLYERQYLGLHGLLPPAFMTQEQQAYRVITKLREQPNDLARYIQLDG 139
Query: 115 LQERNERLFYKLLIDNVEELLPIVYTPVVGEACQKYGSIYKRPQGLYISLKEKG--KILE 172
LQ+RNE+LFY+++ D+V+EL+PIVYTP VG ACQ +G IY++P+GLYI++ + KI +
Sbjct: 140 LQDRNEKLFYRVVCDHVKELMPIVYTPTVGLACQNFGYIYRKPKGLYITINDNSVSKIYQ 199
Query: 173 VLKNWPERSIQVIVVTDGERILGLGDLGCQGMGIPVGKLALYSALGGVRPSACLPVTIDV 232
+L NW E ++ IVVTDGERILGLGDLG G+GIPVGKLALY ALGGV+P CLPV +DV
Sbjct: 200 ILSNWHEEDVRAIVVTDGERILGLGDLGAYGIGIPVGKLALYVALGGVQPKWCLPVLLDV 259
Query: 233 GTNNEKLLNDEFYIGLRQKRATGKEYYDLLHEFMTAVKQNYGEKVLVQFEDFANHNAFEL 292
GTNN LLND FYIGLR KR GK+Y LL FM A + YG+K L+QFEDFAN NAF L
Sbjct: 260 GTNNMDLLNDPFYIGLRHKRVRGKDYDTLLDNFMKACTKKYGQKTLIQFEDFANPNAFRL 319
Query: 293 LAKYGTTHLVFNDDIQGTAAVVLAGVVASLKLIGGTLPEHTFLFLGAGEAGTGIAELIAL 352
L KY + +FNDDIQGTA+V++AG++ ++ + + +LF GAG A TGIAE+I
Sbjct: 320 LDKYQDKYTMFNDDIQGTASVIVAGLLTCTRVTKKLVSQEKYLFFGAGAASTGIAEMIVH 379
Query: 353 EMSKQTKAPIEESRKKIWLVDSKGLIVSSRANSLQHFKKPWAHEHEPVSTLLDAVKIIKP 412
+M + + EE+ +I+L+D GL+ +R + +A + +++L+ ++ +P
Sbjct: 380 QMQNEGISK-EEACNRIYLMDIDGLVTKNR-KEMNPRHVQFAKDMPETTSILEVIRAARP 437
Query: 413 TVLIGSSGVGKTFTKEVVEAMTEINKIPLILALSNPTSQSECTAEEAYTWSEGRAIFASG 472
LIG+S V F +EV+ AM EIN+ P+I ALSNPTS++ECTAEEAYT++ G A++ASG
Sbjct: 438 GALIGASTVRGAFNEEVIRAMAEINERPIIFALSNPTSKAECTAEEAYTFTNGAALYASG 497
Query: 473 SPFDPVEYKGKTYYSGQSNNAYIFPGFGLGIVMSGAIRVHDDMLLAASEALAKQVTEENY 532
SPF E G TY GQ NNAYIFPG LG ++ V +D+ L A++ +A VTE++
Sbjct: 498 SPFPNFELNGHTYKPGQGNNAYIFPGVALGTILFQIRHVDNDLFLLAAKKVASCVTEDSL 557
Query: 533 KKGLTYPPFSDIRKISANIAANVAAKAYE 561
K G YP +IR+IS IA +A Y+
Sbjct: 558 KVGRVYPQLKEIREISIQIAVEMAKYCYK 586
>MAO1_ECOLI (P26616) NAD-dependent malic enzyme (EC 1.1.1.38)
(NAD-ME)
Length = 574
Score = 429 bits (1103), Expect = e-119
Identities = 232/537 (43%), Positives = 342/537 (63%), Gaps = 13/537 (2%)
Query: 51 SGYSLLRDPQYNKGLAFTEKERDAHYLRGLLPPTVSSQQLQEKKLMHNIRQYEVPLQKYV 110
+G LL P NKG AF+ +ER L GLLP V + + Q ++ + ++ + K++
Sbjct: 25 AGPVLLEFPLLNKGSAFSMEERRNFNLLGLLPEVVETIEEQAERAWIQYQGFKTEIDKHI 84
Query: 111 AMMDLQERNERLFYKLLIDNVEELLPIVYTPVVGEACQKYGSIYKRPQGLYISLKEKGKI 170
+ ++Q+ NE LFY+L+ ++++E++P++YTP VG AC+++ IY+R +G++IS + + +
Sbjct: 85 YLRNIQDTNETLFYRLVNNHLDEMMPVIYTPTVGAACERFSEIYRRSRGVFISYQNRHNM 144
Query: 171 LEVLKNWPERSIQVIVVTDGERILGLGDLGCQGMGIPVGKLALYSALGGVRPSACLPVTI 230
++L+N P +I+VIVVTDGERILGLGD G GMGIP+GKL+LY+A GG+ P+ LPV +
Sbjct: 145 DDILQNVPNHNIKVIVVTDGERILGLGDQGIGGMGIPIGKLSLYTACGGISPAYTLPVVL 204
Query: 231 DVGTNNEKLLNDEFYIGLRQKRATGKEYYDLLHEFMTAVKQNYGEKVLVQFEDFANHNAF 290
DVGTNN++LLND Y+G R R T EYY+ + EF+ AVKQ + + VL+QFEDFA NA
Sbjct: 205 DVGTNNQQLLNDPLYMGWRNPRITDDEYYEFVDEFIQAVKQRWPD-VLLQFEDFAQKNAM 263
Query: 291 ELLAKYGTTHLVFNDDIQGTAAVVLAGVVASLKLIGGTLPEHTFLFLGAGEAGTGIAELI 350
LL +Y FNDDIQGTAAV + ++A+ + GG L E +FLGAG AG GIAE+I
Sbjct: 264 PLLNRYRNEICSFNDDIQGTAAVTVGTLIAASRAAGGQLSEKKIVFLGAGSAGCGIAEMI 323
Query: 351 ALEMSKQTKAPIEESRKKIWLVDSKGLIVSSRANSLQHFKKPWAHEHEPVS--------- 401
+ ++ + E +R+K+++VD GL+ N L F+ + E +S
Sbjct: 324 ISQTQREGLSE-EAARQKVFMVDRFGLLTDKMPNLLP-FQTKLVQKRENLSDWDTDSDVL 381
Query: 402 TLLDAVKIIKPTVLIGSSGVGKTFTKEVVEAMTEINKIPLILALSNPTSQSECTAEEAYT 461
+LLD V+ +KP +LIG SG FT+E++ M + P+++ LSNPTS+ E T ++
Sbjct: 382 SLLDVVRNVKPDILIGVSGQTGLFTEEIIREMHKHCPRPIVMPLSNPTSRVEATPQDIIA 441
Query: 462 WSEGRAIFASGSPFDPVEYKGKTYYSGQSNNAYIFPGFGLGIVMSGAIRVHDDMLLAASE 521
W+EG A+ A+GSPF+PV +K K Y Q NNA+IFPG GLG++ SGA R+ D+ML++ASE
Sbjct: 442 WTEGNALVATGSPFNPVVWKDKIYPIAQCNNAFIFPGIGLGVIASGASRITDEMLMSASE 501
Query: 522 ALAKQVTEENYKKGLTYPPFSDIRKISANIAANVAAKAYEL-VCTATIGEQGQFTID 577
LA+ +G+ P DI+K+S IA V A + V T E Q ID
Sbjct: 502 TLAQYSPLVLNGEGMVLPELKDIQKVSRAIAFAVGKMAQQQGVAVKTSAEALQQAID 558
Database: sprot
Posted date: Nov 25, 2004 10:54 AM
Number of letters in database: 59,974,054
Number of sequences in database: 164,201
Lambda K H
0.318 0.136 0.395
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 73,206,604
Number of Sequences: 164201
Number of extensions: 3223408
Number of successful extensions: 9535
Number of sequences better than 10.0: 73
Number of HSP's better than 10.0 without gapping: 46
Number of HSP's successfully gapped in prelim test: 27
Number of HSP's that attempted gapping in prelim test: 9354
Number of HSP's gapped (non-prelim): 98
length of query: 623
length of database: 59,974,054
effective HSP length: 116
effective length of query: 507
effective length of database: 40,926,738
effective search space: 20749856166
effective search space used: 20749856166
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 69 (31.2 bits)
Medicago: description of AC137546.2