BLAST2 result
BLASTP 2.2.2 [Dec-14-2001]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= AC135505.15 - phase: 0 /pseudo
(403 letters)
Database: sprot
164,201 sequences; 59,974,054 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UN47_CAEEL (P34579) Vesicular GABA transporter (Uncoordinated pr... 59 2e-08
AVT1_YEAST (P47082) Vacuolar amino acid transporter 1 58 4e-08
AVT4_YEAST (P50944) Vacuolar amino acid transporter 4 57 1e-07
S361_RAT (Q924A5) Proton-coupled amino acid transporter 1 (Proto... 51 5e-06
AVT3_YEAST (P36062) Vacuolar amino acid transporter 3 50 8e-06
YAN9_SCHPO (Q10074) Hypothetical protein C3H1.09c in chromosome I 50 1e-05
S361_MOUSE (Q8K4D3) Proton-coupled amino acid transporter 1 (Pro... 49 3e-05
S361_HUMAN (Q7Z2H8) Proton-coupled amino acid transporter 1 (Pro... 46 1e-04
S383_MOUSE (Q9DCP2) System N amino acid transporter 1 (SN1) (N-s... 46 2e-04
YSPK_CAEEL (Q19425) Hypothetical protein F13H10.3 in chromosome IV 45 3e-04
S383_HUMAN (Q99624) System N amino acid transporter 1 (SN1) (N-s... 45 4e-04
S383_RAT (Q9JHZ9) System N amino acid transporter 1 (SN1) (N-sys... 43 0.001
AVT6_YEAST (P40074) Vacuolar amino acid transporter 6 42 0.003
Y205_MYCTU (O53656) Hypothetical UPF0118 protein Rv0205/MT0215 37 0.090
YMJ2_CAEEL (P34479) Hypothetical protein F59B2.2 in chromosome III 36 0.15
VIAA_RAT (O35458) Vesicular inhibitory amino acid transporter (G... 35 0.26
VIAA_MACFA (Q95KE2) Vesicular inhibitory amino acid transporter ... 35 0.26
VIAA_HUMAN (Q9H598) Vesicular inhibitory amino acid transporter ... 35 0.26
AVT2_YEAST (P39981) Vacuolar amino acid transporter 2 35 0.26
VIAA_MOUSE (O35633) Vesicular inhibitory amino acid transporter ... 35 0.45
>UN47_CAEEL (P34579) Vesicular GABA transporter (Uncoordinated
protein 47) (Protein unc-47)
Length = 486
Score = 58.9 bits (141), Expect = 2e-08
Identities = 75/379 (19%), Positives = 161/379 (41%), Gaps = 39/379 (10%)
Query: 18 SAFHNVTAMVGAAVLGFPYAMSQLGWGLGITILVLSWICTLYTAWQMIEMHESVSGKRFD 77
+A++ A+ G ++G P A+ GW ++ ++++C +T +IE K+
Sbjct: 94 AAWNVTNAIQGMFIVGLPIAVKVGGWWSIGAMVGVAYVC-YWTGVLLIECLYENGVKKRK 152
Query: 78 KYHELSQHAFGERLGLWIVVPQQLMVEVGIDIVYMVIGAKSLKKLHEILCDDCEPIKTTY 137
Y E++ + G W V+ QL + I+Y+V+ A L+ + + T+
Sbjct: 153 TYREIADF-YKPGFGKW-VLAAQLTELLSTCIIYLVLAADLLQSCFPSVDKAGWMMITSA 210
Query: 138 FIVLFAFVQ--YVLSHLPSFNSVAG--ISLVAAAMSLSYSTIAWIASIHRGALPDVQYSS 193
++ +F+ ++S L FN+++ ++L+ LS+ + Q+S
Sbjct: 211 SLLTCSFLDDLQIVSRLSFFNAISHLIVNLIMVLYCLSFVS---------------QWSF 255
Query: 194 RYSTKAGNIFGIFNALGDIAFGYAGHNVILEIQSTIPSTPEKPSKVSMWRGMIIAYLVVA 253
T + NI + +G + FGY H + ++ + P + + + W +++ A
Sbjct: 256 STITFSLNINTLPTIVGMVVFGYTSHIFLPNLEGNM-KNPAQFNVMLKW-----SHIAAA 309
Query: 254 LCYFPVTIFGYRAFGNSVDDNILLSLEKPRWLIIAANIFVVVHVVGSYQVYAVPVFHMLE 313
+ + G+ FG + I SL + I+ N+ +VV + SY + +L+
Sbjct: 310 VFKVVFGMLGFLTFGELTQEEISNSLPNQSFKIL-VNLILVVKALLSYPLPFYAAVQLLK 368
Query: 314 S--FLAEKMN-----FKPSRFLR---FAIRNLYVSITMVLAITFPFFGGLLSFFGGFVFA 363
+ FL + P + LR +R + V T+ +A++ P+ L+ G
Sbjct: 369 NNLFLGYPQTPFTSCYSPDKSLREWAVTLRIILVLFTLFVALSVPYLVELMGLVGNITGT 428
Query: 364 PTTYFLPCIMWIFIYKPKL 382
++ P + ++I + L
Sbjct: 429 MLSFIWPALFHLYIKEKTL 447
>AVT1_YEAST (P47082) Vacuolar amino acid transporter 1
Length = 602
Score = 58.2 bits (139), Expect = 4e-08
Identities = 71/381 (18%), Positives = 158/381 (40%), Gaps = 32/381 (8%)
Query: 20 FHNVTAMVGAAVLGFPYAMSQLGWGLGITILVLSWICTLYTAWQMIEMHESVSGKRFDKY 79
F+++ ++G +L P + GW +G+T+L + + T TA + + + Y
Sbjct: 215 FNSINVLIGIGLLALPLGLKYAGWVIGLTMLAIFALATFCTAELLSRCLD--TDPTLISY 272
Query: 80 HELSQHAFGERLGLWIVVPQQLMVEVGIDIVYMVIGAKSLKKLHEILCDDCEPIKTTYFI 139
+L AFG + G ++ + +G + +++ SL L TT+F
Sbjct: 273 ADLGYAAFGTK-GRALISALFTLDLLGSGVSLVILFGDSLNALF-------PQYSTTFFK 324
Query: 140 VLFAFVQYVLSHLPSFNSVAGISLVAAAMSLSYSTIAWIASIHRGALP-DVQYSSRYSTK 198
++ F+ +P + ++ ISL+ + + +++ + P + S
Sbjct: 325 IVSFFIVTPPVFIP-LSVLSNISLLGILSTTGTVLVICCCGLYKSSSPGSLVNPMETSMW 383
Query: 199 AGNIFGIFNALGDIAFGYAGHNVILEIQSTIPSTPEKPSKVSMWRGMIIAYLVVALCYFP 258
++ + ++G ++ + GH V +++ + P K + Y + ++
Sbjct: 384 PIDLKHLCLSIGLLSACWGGHAVFPNLKTDM----RHPDKFK--DCLKTTYKITSVTDIG 437
Query: 259 VTIFGYRAFGNSVDD----NILLSLEKPRWLIIAANIFVVVHVVGSYQVYAVPVFHMLES 314
+ G+ FGN V D N+LL+ P+++ + + + + + A P+ +L+
Sbjct: 438 TAVIGFLMFGNLVKDEITKNVLLTEGYPKFVYGLISALMTIIPIAKTPLNARPIVSVLDV 497
Query: 315 FL-AEKMNFKPSRFLRFAIRNL------YVSITMVL-AITFPFFGGLLSFFGGFVFAPTT 366
+ + ++ S R A + L ++++ VL AI FP F +++F G +
Sbjct: 498 LMNVQHIDEAASAIKRRAAKGLQVFNRIFINVVFVLIAINFPEFDKIIAFLGAGLCFTIC 557
Query: 367 YFLPCIMWIFIYKPKLFSLSW 387
LPC W ++ K W
Sbjct: 558 LILPC--WFYLRLCKTTIKPW 576
>AVT4_YEAST (P50944) Vacuolar amino acid transporter 4
Length = 713
Score = 56.6 bits (135), Expect = 1e-07
Identities = 73/379 (19%), Positives = 157/379 (41%), Gaps = 48/379 (12%)
Query: 25 AMVGAAVLGFPYAMSQLGWGLGITILVLSWICTLYTAWQMIEMHESVSGKRFDKYHELSQ 84
+ +G VL P A G +++L I Y+ W + ++ S + ++
Sbjct: 309 SFIGTGVLFLPNAFHNGGLFFSVSMLAFFGI---YSYWCYYILVQAKSSCGVSSFGDIGL 365
Query: 85 HAFGERLGLWIVVPQQLMVEVGIDIVYMVIGAKSLKK-LHEILCDDCEPIKTTYFIVLFA 143
+G + + I++ ++ +VG YM+ AK+L+ L + P+ +Y +V
Sbjct: 366 KLYGPWMRI-IILFSLVITQVGFSGAYMIFTAKNLQAFLDNVFHVGVLPL--SYLMVFQT 422
Query: 144 FVQYVLSHLPSFNSVAGISLVAAAMSLSYSTIAWIASIHRGALPDVQYSSRYSTKAGNIF 203
+ LS + + + ++ SL+A ++ I I + R + + + G ++
Sbjct: 423 IIFIPLSFIRNISKLSLPSLLANFFIMAGLVIVIIFTAKR-----LFFDLMGTPAMGVVY 477
Query: 204 GIFNA------LGDIAFGYAGHNVILEIQSTIPSTPEKPSKVSMWRGMIIAYLVVALCYF 257
G+ NA +G F + G +I+ +Q ++ P K + ++I L + +
Sbjct: 478 GL-NADRWTLFIGTAIFAFEGIGLIIPVQDSM----RNPEKFPLVLALVI--LTATILFI 530
Query: 258 PVTIFGYRAFGNSVDDNILLSLEKPRWLIIAANIFVVVHVVGSYQVYAVPVFHMLES--- 314
+ GY A+G++V ILL+L + + +F + ++ S + P ++E+
Sbjct: 531 SIATLGYLAYGSNVQTVILLNLPQSNIFVNLIQLFYSIAIMLSTPLQLFPAIKIIENKFF 590
Query: 315 -----------FLAEKMNFKP-SRFLRFAI---RNLYVSITMVLAITFPFFGG-----LL 354
L ++ +P S L + I +N SI +++ ++ +FG +
Sbjct: 591 PKFTKIYVKHDDLTTRVELRPNSGKLNWKIKWLKNFIRSIIVIIVVSIAYFGSDNLDKFV 650
Query: 355 SFFGGFVFAPTTYFLPCIM 373
S G P Y P ++
Sbjct: 651 SVIGSLACIPLVYIYPSML 669
>S361_RAT (Q924A5) Proton-coupled amino acid transporter 1
(Proton/amino acid transporter 1) (Solute carrier family
36 member 1) (Lysosomal amino acid transporter 1)
(LYAAT-1) (Neutral amino acid/proton symporter)
Length = 475
Score = 51.2 bits (121), Expect = 5e-06
Identities = 80/393 (20%), Positives = 158/393 (39%), Gaps = 58/393 (14%)
Query: 21 HNVTAMVGAAVLGFPYAMSQLGWGLGITILVLSWICTLYTAWQMIEMHESVS---GKRFD 77
H + +G +LG P A+ G LG L++ I ++ +++ + K F
Sbjct: 54 HLLKGNIGTGLLGLPLAVKNAGLLLGPLSLLVIGIVAVHCMGILVKCAHHLCRRLNKPFL 113
Query: 78 KYHELSQHAFGERLGLWI---------VVPQQLMV-EVGIDIVYMVIGAKSLKKLHEIL- 126
Y + + WI +V L+V ++G VY V A + K++ E
Sbjct: 114 DYGDTVMYGLECSPSTWIRNHSHWGRRIVDFFLVVTQLGFCCVYFVFLADNFKQVIEAAN 173
Query: 127 -----CDDCEPIKTTY-------------FIVLFAFVQYVLSHLPSFNSVAGISLVAAAM 168
C++ E + T F+VL +F++ L L F+ +A IS+ + +
Sbjct: 174 GTTTNCNNNETVILTPTMDSRLYMLTFLPFLVLLSFIRN-LRILSIFSLLANISMFVSLI 232
Query: 169 SLSYSTIAWIASIHRGALPDVQYSSRYSTKAGNIFGIFNALGDIAFGYAGHNVILEIQST 228
+ + I PD + + + +F G F + G V+L +++
Sbjct: 233 MIYQFIVQRI--------PDPSHLPLVAP--WKTYPLF--FGTAIFAFEGIGVVLPLENK 280
Query: 229 IPSTPEKPSKVSMWRGMIIAYLVVALCYFPVTIFGYRAFGNSVDDNILLSLEKPRWLIIA 288
+ + + P + ++ GM I + + Y + GY FG + +I L+L WL +
Sbjct: 281 MKDSQKFP--LILYLGMAI----ITVLYISLGSLGYLQFGADIKGSITLNLPN-CWLYQS 333
Query: 289 ANIFVVVHVVGSYQVYAVPVFHMLESFLAEKMNFKPSRF---LRFAIRNLYVSITMVLAI 345
+ ++ +G + YA+ + E + ++ P RF + + R V +T VLA+
Sbjct: 334 VKL---LYSIGIFFTYALQFYVAAEIIIPAIVSRVPERFELVVDLSARTAMVCVTCVLAV 390
Query: 346 TFPFFGGLLSFFGGFVFAPTTYFLPCIMWIFIY 378
P ++S G + +P ++ + Y
Sbjct: 391 LIPRLDLVISLVGSVSSSALALIIPPLLEVTTY 423
>AVT3_YEAST (P36062) Vacuolar amino acid transporter 3
Length = 692
Score = 50.4 bits (119), Expect = 8e-06
Identities = 74/370 (20%), Positives = 147/370 (39%), Gaps = 30/370 (8%)
Query: 25 AMVGAAVLGFPYAMSQLGWGLGITILVLSWICTLYTAWQMIEMHESVSGKRFDKYHELSQ 84
+ VG VL P A GWG L+ C L + + + + D Y ++ +
Sbjct: 309 SFVGTGVLFLPKAFHNGGWGFSALCLLS---CALISYGCFVSLITTKDKVGVDGYGDMGR 365
Query: 85 HAFGERLGLWIVVPQQLMVEVGIDIVYMVIGAKSLKKLHEI---LCDDCEPIKTTYFIVL 141
+G ++ + ++ + ++G Y V A +L+ E L + T F +
Sbjct: 366 ILYGPKMK-FAILSSIALSQIGFSAAYTVFTATNLQVFSENFFHLKPGSISLATYIFAQV 424
Query: 142 FAFVQYVLSHLPSFNSVAGISLVAAAMSLSYSTIAWIASIHRGALPDVQYSSRYSTKAGN 201
FV L+ + ++G +L+A L ++ SI+ A+ V + +
Sbjct: 425 LIFVPLSLTR--NIAKLSGTALIADLFILLGLVYVYVYSIYYIAVNGVASDTMLMFNKAD 482
Query: 202 IFGIFNALGDIAFGYAGHNVILEIQSTIPSTPE-KPSKVSMWRGMIIAYLVVALCYFPVT 260
+ +F +G F + G +++ IQ ++ +PS + +VA+ +
Sbjct: 483 -WSLF--IGTAIFTFEGIGLLIPIQESMKHPKHFRPS-------LSAVMCIVAVIFISCG 532
Query: 261 IFGYRAFGNSVDDNILLSLEKPRWLIIAANIFVVVHVVGSYQVYAVPVFHMLESF----- 315
+ Y AFG+ V +LL+ + + + + ++ S + P +LE++
Sbjct: 533 LLCYAAFGSDVKTVVLLNFPQDTSYTLTVQLLYALAILLSTPLQLFPAIRILENWTFPSN 592
Query: 316 LAEKMNFKPSRFLRFAIRNLYVSITMVLA-ITFPFFGGLLSFFGGFVFAPTTYFLPCIMW 374
+ K N K ++L+ R V +T +LA + +S G F P Y P ++
Sbjct: 593 ASGKYNPK-VKWLKNYFRCAIVVLTSILAWVGANDLDKFVSLVGSFACIPLIYIYPPLLH 651
Query: 375 IFIYKPKLFS 384
YK + S
Sbjct: 652 ---YKASILS 658
>YAN9_SCHPO (Q10074) Hypothetical protein C3H1.09c in chromosome I
Length = 656
Score = 50.1 bits (118), Expect = 1e-05
Identities = 77/380 (20%), Positives = 161/380 (42%), Gaps = 47/380 (12%)
Query: 25 AMVGAAVLGFPYAMSQLGWGLGITIL----VLSWICTLYTAWQMIEMHESVSGKRFDKYH 80
+ VG VL P A G L VLS IC L +I+ V G +
Sbjct: 287 SFVGTGVLFLPKAFKLGGLVFSSATLLIVGVLSHICFLL----LIQTRMKVPGS----FG 338
Query: 81 ELSQHAFGERLGLWIVVPQQLMVEVGIDIVYMVIGAKSLKKLHEILCDDCEPIKTTYFIV 140
++ +G + + ++ ++ ++G Y+ A +L+ +++ Y +
Sbjct: 339 DIGGTLYGPHMR-FAILASIVVSQIGFSSAYISFVASTLQACVKVI----STTHREYHLA 393
Query: 141 LFAFVQYV----LSHLPSFNSVAGISLVAAA---MSLSYSTIAWIASIHRGALPDVQYSS 193
+F F+Q++ LS + + ++ +L+A + + Y + ++ + DV +
Sbjct: 394 VFIFIQFLVFVPLSLVRKISKLSATALIADVFILLGILYLYFWDVITLATKGIADVAMFN 453
Query: 194 RYSTKAGNIFGIFNALGDIAFGYAGHNVILEIQSTIPSTPEKPSKVSMWRGMIIAYLVVA 253
+ F +F +G F Y G +IL IQ + P ++ G++ A ++
Sbjct: 454 KTD------FSLF--IGVAIFTYEGICLILPIQEQMAKPKNLPKLLT---GVMAA---IS 499
Query: 254 LCYFPVTIFGYRAFGNSVDDNILLSLEKPRWLIIAANIFVVVHVVGSYQVYAVPVFHMLE 313
L + + + Y AFG+ V ++L++ + + +I ++ + ++ S + P ++E
Sbjct: 500 LLFISIGLLSYAAFGSKVKTVVILNMPESTFTVIIQFLYAIA-ILLSTPLQLFPAIAIIE 558
Query: 314 SFLAEKMNFKPSRFLRFAIRNLYVSITMVLAITFPFFGGL-LSFFGGFVFAPTTYFLPCI 372
+ + K +R +++ L V I ++LAI + G L F V + + CI
Sbjct: 559 QGIFTRSG-KRNRKIKWRKNYLRVLI-VILAILISWAGSSRLDLFVSMVGS-----VCCI 611
Query: 373 MWIFIYKPKLFSLSWCANWV 392
I++Y P L + NW+
Sbjct: 612 PLIYMYPPMLHYKACANNWI 631
>S361_MOUSE (Q8K4D3) Proton-coupled amino acid transporter 1
(Proton/amino acid transporter 1) (Solute carrier family
36 member 1)
Length = 475
Score = 48.5 bits (114), Expect = 3e-05
Identities = 78/393 (19%), Positives = 157/393 (39%), Gaps = 58/393 (14%)
Query: 21 HNVTAMVGAAVLGFPYAMSQLGWGLGITILVLSWICTLYTAWQMIEMHESVS---GKRFD 77
H + +G +LG P A+ G LG L++ I ++ +++ + K F
Sbjct: 54 HLLKGNIGTGLLGLPLAVKNAGLLLGPLSLLVIGIVAVHCMGILVKCAHHLCRRLNKPFL 113
Query: 78 KYHELSQHAFGERLGLWI---------VVPQQLMV-EVGIDIVYMVIGAKSLKKLHEIL- 126
Y + + W+ +V L+V ++G VY V A + K++ E
Sbjct: 114 DYGDTVMYGLECSPSTWVRNHSHWGRRIVDFFLIVTQLGFCCVYFVFLADNFKQVIEAAN 173
Query: 127 -----CDDCEPIKTTY-------------FIVLFAFVQYVLSHLPSFNSVAGISLVAAAM 168
C++ + T F+VL +F++ L L F+ +A IS+ + +
Sbjct: 174 GTTTNCNNNVTVIPTPTMDSRLYMLSFLPFLVLLSFIRN-LRVLSIFSLLANISMFVSLI 232
Query: 169 SLSYSTIAWIASIHRGALPDVQYSSRYSTKAGNIFGIFNALGDIAFGYAGHNVILEIQST 228
+ + I PD + + + +F G F + G V+L +++
Sbjct: 233 MIYQFIVQRI--------PDPSHLPLVAP--WKTYPLF--FGTAIFAFEGIGVVLPLENK 280
Query: 229 IPSTPEKPSKVSMWRGMIIAYLVVALCYFPVTIFGYRAFGNSVDDNILLSLEKPRWLIIA 288
+ + + P + ++ GM I + + Y + GY FG ++ +I L+L WL +
Sbjct: 281 MKDSQKFP--LILYLGMAI----ITVLYISLGSLGYLQFGANIKGSITLNLPN-CWLYQS 333
Query: 289 ANIFVVVHVVGSYQVYAVPVFHMLESFLAEKMNFKPSRF---LRFAIRNLYVSITMVLAI 345
+ ++ +G + YA+ + E + ++ P F + +R V +T VLAI
Sbjct: 334 VKL---LYSIGIFFTYALQFYVAAEIIIPAIVSRVPEHFELMVDLCVRTAMVCVTCVLAI 390
Query: 346 TFPFFGGLLSFFGGFVFAPTTYFLPCIMWIFIY 378
P ++S G + +P ++ + Y
Sbjct: 391 LIPRLDLVISLVGSVSSSALALIIPPLLEVVTY 423
>S361_HUMAN (Q7Z2H8) Proton-coupled amino acid transporter 1
(Proton/amino acid transporter 1) (Solute carrier family
36 member 1)
Length = 476
Score = 46.2 bits (108), Expect = 1e-04
Identities = 71/378 (18%), Positives = 147/378 (38%), Gaps = 38/378 (10%)
Query: 21 HNVTAMVGAAVLGFPYAMSQLGWGLGITILVLSWICTLYTAWQMIEMHESVS---GKRFD 77
H + +G +LG P A+ G +G L++ I ++ +++ K F
Sbjct: 55 HLLKGNIGTGLLGLPLAVKNAGIVMGPISLLIIGIVAVHCMGILVKCAHHFCRRLNKSFV 114
Query: 78 KYHELSQHAFGERLGLWI---------VVPQQLMV-EVGIDIVYMVIGAKSLKKLHEIL- 126
Y + + W+ VV L+V ++G VY V A + K++ E
Sbjct: 115 DYGDTVMYGLESSPCSWLRNHAHWGRRVVDFFLIVTQLGFCCVYFVFLADNFKQVIEAAN 174
Query: 127 --CDDCEPIKTTYFIVLFAFVQYVLSHLP---------SFNSVAGISLVAAAMSLSYSTI 175
++C +T Y+LS LP + +++ SL+A L +
Sbjct: 175 GTTNNCHNNETVILTPTMDSRLYMLSFLPFLVLLVFIRNLRALSIFSLLANITMLVSLVM 234
Query: 176 AWIASIHRGALPDVQYSSRYSTKAGNIFGIFNALGDIAFGYAGHNVILEIQSTIPSTPEK 235
+ + R +PD + + + +F G F + G ++L +++ + +
Sbjct: 235 IYQFIVQR--IPDPSHLPLVAP--WKTYPLF--FGTAIFSFEGIGMVLPLENKMKDPRKF 288
Query: 236 PSKVSMWRGMIIAYLVVALCYFPVTIFGYRAFGNSVDDNILLSLEKPRWLIIAANIFVVV 295
P + ++ GM+I V + Y + GY FG ++ +I L+L WL + + +
Sbjct: 289 P--LILYLGMVI----VTILYISLGCLGYLQFGANIQGSITLNLPN-CWLYQSVKLLYSI 341
Query: 296 HVVGSYQVYAVPVFHMLESFLAEKMNFKPSRFLRFAIRNLYVSITMVLAITFPFFGGLLS 355
+ +Y + ++ F + + +R + V +T +LAI P ++S
Sbjct: 342 GIFFTYALQFYVPAEIIIPFFVSRAPEHCELVVDLFVRTVLVCLTCILAILIPRLDLVIS 401
Query: 356 FFGGFVFAPTTYFLPCIM 373
G + +P ++
Sbjct: 402 LVGSVSSSALALIIPPLL 419
>S383_MOUSE (Q9DCP2) System N amino acid transporter 1 (SN1)
(N-system amino acid transporter 1) (Solute carrier
family 38, member 3) (mNAT)
Length = 505
Score = 45.8 bits (107), Expect = 2e-04
Identities = 81/400 (20%), Positives = 152/400 (37%), Gaps = 62/400 (15%)
Query: 18 SAFHNVTAMVGAAVLGFPYAMSQLGWGLGITILVLSWICTLYTAWQMIEMHESVSGKRFD 77
S F+ A++G+ +LG YAM+ G L + +L + + Y+ +++ + G R
Sbjct: 70 SVFNLSNAIMGSGILGLAYAMANTGIILFLFLLTAVALLSSYSIHLLLKS-SGIVGIR-- 126
Query: 78 KYHELSQHAFGE--RLGLWIVVPQQLMVEVGIDIVYMVIGAKSLKKLHEILCDDCEPIKT 135
Y +L AFG +L + + Q +G Y+ I L + + + +P
Sbjct: 127 AYEQLGYRAFGTPGKLAAALAITLQ---NIGAMSSYLYIIKSELPLVIQTFLNLEKPASV 183
Query: 136 TY----FIVLFAFVQYVLSHLPSFNSVAGISLVAAAMSLSYSTIAWIASIHRGALPDVQY 191
Y ++V+ V +L + G ++ SLS IA I++
Sbjct: 184 WYMDGNYLVILVSVTIILPL--ALMRQLGYLGYSSGFSLSCMVFFLIAVIYKKFQVPCPL 241
Query: 192 SSRYSTKAGNIFGIFNA--------------------------------LGDIAFGYAGH 219
+ + GN + A + +AF + H
Sbjct: 242 AHNLANATGNFSHMVVAEEKAQLQGEPDTAAEAFCTPSYFTLNSQTAYTIPIMAFAFVCH 301
Query: 220 NVILEIQSTIPSTPEKPSKVSMWRGMIIAYLVVALCYFPVTIFGYRAFGNSVDDNILLSL 279
+L I + + + PSK M ++ V+ + YF +FGY F + V+ +L +
Sbjct: 302 PEVLPIYTEL----KDPSKRKMQHISNLSIAVMYVMYFLAALFGYLTFYDGVESELLHTY 357
Query: 280 EKP---RWLIIAANIFVVVHVVGSYQVYAVPVFHMLESFLAEKMNFKPSRFLRFAIRNLY 336
K LI+ + V++ V + + PV ++ L + F R + A L
Sbjct: 358 SKVDPFDVLILCVRVAVLIAVTLTVPIVLFPVRRAIQQMLFQNQEFSWLRHVLIATGLLT 417
Query: 337 VSITMVLAITFPFFGGLLSFFGGFVFAPTTYFLPCIMWIF 376
+V+ F +L FG + T+ PC+++IF
Sbjct: 418 CINLLVI-----FAPNILGIFG--IIGATS--APCLIFIF 448
>YSPK_CAEEL (Q19425) Hypothetical protein F13H10.3 in chromosome IV
Length = 615
Score = 45.4 bits (106), Expect = 3e-04
Identities = 32/115 (27%), Positives = 58/115 (49%), Gaps = 5/115 (4%)
Query: 26 MVGAAVLGFPYAMSQLGWGLGITILVLSWICTLYTAWQMIEMHESVSGKRFD----KYHE 81
M+G ++L P+A+ Q G LGI I++ YTA+ +IE + + D ++ +
Sbjct: 176 MMGTSLLAMPWALQQAGLVLGIIIMLSMAAICFYTAYIVIESPKRLQDLSVDPLLAEFSD 235
Query: 82 LSQHAFGERLGLWIVVPQQLMVEVGIDIVYMVIGAKSLKKLHEILCDDCEPIKTT 136
+ + FG R+G + V + V +G IVY V+ + L ++ + +P TT
Sbjct: 236 VCKSLFG-RIGEYCAVVFSVCVLIGGVIVYWVLMSNFLYYTGAVVYESMQPNSTT 289
Score = 34.7 bits (78), Expect = 0.45
Identities = 37/169 (21%), Positives = 66/169 (38%), Gaps = 11/169 (6%)
Query: 210 GDIAFGYAGHNVILEIQSTIPSTPEKPSKVSMWRGMIIAYLVVALCYFPVTIFGYRAF-- 267
G + Y HN +L TI + P + R + I Y +VA CY + + AF
Sbjct: 421 GTLTLSYFIHNAVL----TILRNQKHPENNA--RDLSIGYCLVAFCYVFIGFTFFAAFPV 474
Query: 268 -GNSVDDNILLSLEKPRWLIIAANIFVVVHVVGSYQVYAVPVFHMLESFLAEKMNFKPSR 326
+ + DN L + L A +F++ ++ + V L F A P
Sbjct: 475 QRSCISDNFLNNFGAGDVLSSTARLFLLFQMITVLPLLMFLVRSQL--FYAIFGQTWPGA 532
Query: 327 FLRFAIRNLYVSITMVLAITFPFFGGLLSFFGGFVFAPTTYFLPCIMWI 375
+ L +++ + A +P G +L + G + LP +++I
Sbjct: 533 IRVIILNVLLIAVAVGFATFYPNVGSILRYVGSISGLVYVFALPAMVYI 581
>S383_HUMAN (Q99624) System N amino acid transporter 1 (SN1)
(N-system amino acid transporter 1) (Solute carrier
family 38, member 3)
Length = 504
Score = 44.7 bits (104), Expect = 4e-04
Identities = 81/395 (20%), Positives = 143/395 (35%), Gaps = 56/395 (14%)
Query: 18 SAFHNVTAMVGAAVLGFPYAMSQLGWGLGITILVLSWICTLYTAWQMIEMHESVSGKRFD 77
S F+ A++G+ +LG YAM+ G L + +L + + Y+ +++ V G R
Sbjct: 71 SVFNLSNAIMGSGILGLAYAMANTGIILFLFLLTAVALLSSYSIHLLLKS-SGVVGIR-- 127
Query: 78 KYHELSQHAFGE--RLGLWIVVPQQLMVEVGIDIVYMVIGAKSLKKLHEILCDDCEPIKT 135
Y +L AFG +L + + Q +G Y+ I L + + + E
Sbjct: 128 AYEQLGYRAFGTPGKLAAALAITLQ---NIGAMSSYLYIIKSELPLVIQTFLNLEEKTSD 184
Query: 136 TY----FIVLFAFVQYVLSHLPSFNSVAGISLVAAAMSLSYSTIAWIASIHRGALPDVQY 191
Y ++V+ V +L + G ++ SLS IA I++
Sbjct: 185 WYMNGNYLVILVSVTIILPL--ALMRQLGYLGYSSGFSLSCMVFFLIAVIYKKFHVPCPL 242
Query: 192 SSRYSTKAGNIFGI------------------------------FNALGDIAFGYAGHNV 221
++ GN + + +AF + H
Sbjct: 243 PPNFNNTTGNFSHVEIVKEKVQLQVEPEASAFCTPSYFTLNSQTAYTIPIMAFAFVCHPE 302
Query: 222 ILEIQSTIPSTPEKPSKVSMWRGMIIAYLVVALCYFPVTIFGYRAFGNSVDDNILLSLEK 281
+L I + + + PSK M ++ V+ + YF +FGY F N V+ +L + K
Sbjct: 303 VLPIYTEL----KDPSKKKMQHISNLSIAVMYIMYFLAALFGYLTFYNGVESELLHTYSK 358
Query: 282 P---RWLIIAANIFVVVHVVGSYQVYAVPVFHMLESFLAEKMNFKPSRFLRFAIR----- 333
LI+ + V+ V + + PV ++ L F R + A+
Sbjct: 359 VDPFDVLILCVRVAVLTAVTLTVPIVLFPVRRAIQQMLFPNQEFSWLRHVLIAVGLLTCI 418
Query: 334 NLYVSITMVLAITFPFFGGLLSFFGGFVFAPTTYF 368
NL V + F G + F F+F YF
Sbjct: 419 NLLVIFAPNILGIFGVIGATSAPFLIFIFPAIFYF 453
>S383_RAT (Q9JHZ9) System N amino acid transporter 1 (SN1) (N-system
amino acid transporter 1) (Solute carrier family 38,
member 3)
Length = 504
Score = 43.1 bits (100), Expect = 0.001
Identities = 81/399 (20%), Positives = 152/399 (37%), Gaps = 61/399 (15%)
Query: 18 SAFHNVTAMVGAAVLGFPYAMSQLGWGLGITILVLSWICTLYTAWQMIEMHESVSGKRFD 77
S F+ A++G+ +LG YAM+ G L + +L + + Y+ +++ + G R
Sbjct: 70 SVFNLSNAIMGSGILGLAYAMANTGIILFLFLLTAVALLSSYSIHLLLKS-SGIVGIR-- 126
Query: 78 KYHELSQHAFGE--RLGLWIVVPQQLMVEVGIDIVYMVIGAKSLKKLHEILCDDCEPIKT 135
Y +L AFG +L + + Q +G Y+ I L + + + +P
Sbjct: 127 AYEQLGYRAFGTPGKLAAALAITLQ---NIGAMSSYLYIIKSELPLVIQTFLNLEKPTPV 183
Query: 136 TY----FIVLFAFVQYVLSHLPSFNSVAGISLVAAAMSLSYSTIAWIASIHRGALPDVQY 191
Y ++V+ V +L + G ++ SLS IA I++
Sbjct: 184 WYMDGNYLVILVSVIIILPL--ALMRQLGYLGYSSGFSLSCMVFFLIAVIYKKFQVPCPL 241
Query: 192 SSRYSTKAGNI--------------------------FGIFNA-----LGDIAFGYAGHN 220
+ GN + N+ + +AF + H
Sbjct: 242 AHNLVNATGNFSHMVVVEEKSQLQSEPDTAEAFCTPSYFTLNSQTAYTIPIMAFAFVCHP 301
Query: 221 VILEIQSTIPSTPEKPSKVSMWRGMIIAYLVVALCYFPVTIFGYRAFGNSVDDNILLSLE 280
+L I + + + PSK M ++ V+ + YF +FGY F + V+ +L +
Sbjct: 302 EVLPIYTEL----KDPSKRKMQHISNLSIAVMYVMYFLAALFGYLTFYDGVESELLHTYS 357
Query: 281 KP---RWLIIAANIFVVVHVVGSYQVYAVPVFHMLESFLAEKMNFKPSRFLRFAIRNLYV 337
K LI+ + V++ V + + PV ++ L + F R + A L
Sbjct: 358 KVDPFDVLILCVRVAVLIAVTLTVPIVLFPVRRAIQQMLFQNQEFSWLRHVLIATGLLTC 417
Query: 338 SITMVLAITFPFFGGLLSFFGGFVFAPTTYFLPCIMWIF 376
+V+ F +L FG + T+ PC+++IF
Sbjct: 418 INLLVI-----FAPNILGIFG--IIGATS--APCLIFIF 447
>AVT6_YEAST (P40074) Vacuolar amino acid transporter 6
Length = 448
Score = 42.0 bits (97), Expect = 0.003
Identities = 56/259 (21%), Positives = 102/259 (38%), Gaps = 22/259 (8%)
Query: 28 GAAVLGFPYAMSQLGWGLGITILVLSWICTLYTAWQMIEMHESVSGKR--FDKYHELSQH 85
GA +L PYA G G+ ++VL C + + + + + V R F L
Sbjct: 18 GAGILAMPYAFKPFGLIPGVIMIVLCGACAMQSLFIQARVAKYVPQGRASFSALTRLINP 77
Query: 86 AFGERLGLWIVVPQQLMVEVGIDIVYMVIGAKSLKKLHEILCDDCEPI-KTTYFIVLFAF 144
G L I + G+ + YM++ + ++ + + + + ++ F
Sbjct: 78 NLGIVFDLAIAIKC-----FGVGVSYMIVVGDLMPQIMSVWTRNAWLLNRNVQISLIMLF 132
Query: 145 VQYVLSHLPSFNSVAGISLVAAAMSLSYSTIAWIASIHRGALPD--VQYSSRYS---TKA 199
LS L NS+ S+VA + S++Y + + +H A D ++ R S
Sbjct: 133 FVAPLSFLKKLNSLRYASMVAIS-SVAYLCV--LVLLHYVAPSDEILRLKGRISYLLPPQ 189
Query: 200 GNIFGIFNALGDIAFGY-AGHNVILEIQSTIPSTPEKPSKVSMWRGMIIAYLVVALCYFP 258
+ + N L F Y HN+ I S E K+ +IA + + Y
Sbjct: 190 SHDLNVLNTLPIFVFAYTCHHNMFSIINEQRSSRFEHVMKIP-----LIAISLALILYIA 244
Query: 259 VTIFGYRAFGNSVDDNILL 277
+ GY FG+++ NI++
Sbjct: 245 IGCAGYLTFGDNIIGNIIM 263
>Y205_MYCTU (O53656) Hypothetical UPF0118 protein Rv0205/MT0215
Length = 367
Score = 37.0 bits (84), Expect = 0.090
Identities = 25/76 (32%), Positives = 42/76 (54%), Gaps = 7/76 (9%)
Query: 283 RWLIIAANIFVVVHVVGSYQVYAVPVFH--MLESFLAEKMNFKPSRFLRFAIRNLYVSIT 340
R+L+I A + ++ V+ ++V VPV ML + L +++ SR L A V++T
Sbjct: 23 RFLVILAAMVALLWVLNKFEVIVVPVLLALMLSALLVPPVDWLDSRGLPHA-----VAVT 77
Query: 341 MVLAITFPFFGGLLSF 356
+VL F GG+L+F
Sbjct: 78 LVLLSGFAVLGGILTF 93
>YMJ2_CAEEL (P34479) Hypothetical protein F59B2.2 in chromosome III
Length = 460
Score = 36.2 bits (82), Expect = 0.15
Identities = 30/155 (19%), Positives = 63/155 (40%), Gaps = 10/155 (6%)
Query: 199 AGNIFGIFNALGDIAFGYAGHNVILEIQSTIPSTPEKPSKVSMWRGMIIAYLVVALCYFP 258
A N G +G + + G +IL I++ + + P+ G++ +++ +
Sbjct: 230 ATNFTGTITMIGMSMYAFEGQTMILPIENKL----DNPAAFLAPFGVLSTTMIICTAFMT 285
Query: 259 VT-IFGYRAFGNSVDDNILLSLEKPRWLIIAANIFVVVHVVGSYQVYAVPVFHMLESFLA 317
FGY FG+S+ I ++ K L N+F+++ + + V+ M +
Sbjct: 286 ALGFFGYTGFGDSIAPTITTNVPK-EGLYSTVNVFLMLQSLLGNSIAMYVVYDMFFNGFR 344
Query: 318 EKMNFK----PSRFLRFAIRNLYVSITMVLAITFP 348
K + P R +V +T ++A+ P
Sbjct: 345 RKFGARFPNVPKWLSDKGFRVFWVLVTYLMAVLIP 379
>VIAA_RAT (O35458) Vesicular inhibitory amino acid transporter (GABA
and glycine transporter) (Vesicular GABA transporter)
(rGVAT)
Length = 525
Score = 35.4 bits (80), Expect = 0.26
Identities = 84/390 (21%), Positives = 157/390 (39%), Gaps = 47/390 (12%)
Query: 17 YSAFHNVT-AMVGAAVLGFPYAMSQLGWGLGITILVLSWICTLYTAWQMIEM--HESVSG 73
+ A NVT A+ G VLG PYA+ G+ LG+ +++ + + YT +I E+ G
Sbjct: 119 WEAGWNVTNAIQGMFVLGLPYAILHGGY-LGLFLIIFAAVVCCYTGKILIACLYEENEDG 177
Query: 74 KRF---DKYHELSQHAFGER---LGLWIVVPQQLMVEVGIDIVYMVIGAKSLKKLHEILC 127
+ D Y ++ R LG +V Q++ V I+Y+V+ + L
Sbjct: 178 EVVRVRDSYVAIANACCAPRFPTLGGRVVNVAQIIELVMTCILYVVVSGNLMYNSFPGL- 236
Query: 128 DDCEPIKTTYFIVLFAFVQYVLSHLPSFNSVAGISLVA--AAMSLSYSTIAWIASIHRG- 184
P+ + ++ V + L + +V+ SL+ A ++ IA+ S R
Sbjct: 237 ----PVSQKSWSIIATAVLLPCAFLKNLKAVSKFSLLCTLAHFVINILVIAYCLSRARDW 292
Query: 185 ALPDVQYSSRYSTKAGNIFGIFNALGDIAFGYAGHNVILEIQSTIPSTPEKPSKVSMWRG 244
A V++ F I ++G I F Y + ++ + ++PS+
Sbjct: 293 AWEKVKFYIDVKK-----FPI--SIGIIVFSYTSQIFLPSLEGNM----QQPSEFHC--- 338
Query: 245 MIIAYLVVALCYFP--VTIFGYRAFGNSVDDNILLSLEKPRWLIIAANIFVVVHVVGSYQ 302
++ + +A C + Y + + + I +L P + NIF+V + SY
Sbjct: 339 -MMNWTHIAACVLKGLFALVAYLTWADETKEVITDNL--PGSIRAVVNIFLVAKALLSYP 395
Query: 303 VYAVPVFHMLESFLAEKMN--FKPSRF--------LRFAIRNLYVSITMVLAITFPFFGG 352
+ +LE L ++ + F P+ + +R V T+++AI P F
Sbjct: 396 LPFFAAVEVLEKSLFQEGSRAFFPACYGGDGRLKSWGLTLRCALVVFTLLMAIYVPHFAL 455
Query: 353 LLSFFGGFVFAPTTYFLPCIMWIFIYKPKL 382
L+ G A + LP + + + KL
Sbjct: 456 LMGLTGSLTGAGLCFLLPSLFHLRLLWRKL 485
>VIAA_MACFA (Q95KE2) Vesicular inhibitory amino acid transporter
(GABA and glycine transporter) (Vesicular GABA
transporter) (QccE-21148)
Length = 525
Score = 35.4 bits (80), Expect = 0.26
Identities = 84/390 (21%), Positives = 157/390 (39%), Gaps = 47/390 (12%)
Query: 17 YSAFHNVT-AMVGAAVLGFPYAMSQLGWGLGITILVLSWICTLYTAWQMIEM--HESVSG 73
+ A NVT A+ G VLG PYA+ G+ LG+ +++ + + YT +I E+ G
Sbjct: 119 WEAGWNVTNAIQGMFVLGLPYAILHGGY-LGLFLIIFAAVVCCYTGKILIACLYEENEDG 177
Query: 74 KRF---DKYHELSQHAFGER---LGLWIVVPQQLMVEVGIDIVYMVIGAKSLKKLHEILC 127
+ D Y ++ R LG +V Q++ V I+Y+V+ + L
Sbjct: 178 EVVRVRDSYVAIANACCAPRFPTLGGRVVNVAQIIELVMTCILYVVVSGNLMYNSFPGL- 236
Query: 128 DDCEPIKTTYFIVLFAFVQYVLSHLPSFNSVAGISLVA--AAMSLSYSTIAWIASIHRG- 184
P+ + ++ V + L + +V+ SL+ A ++ IA+ S R
Sbjct: 237 ----PVSQKSWSIIATAVLLPCAFLKNLKAVSKFSLLCTLAHFVINILVIAYCLSRARDW 292
Query: 185 ALPDVQYSSRYSTKAGNIFGIFNALGDIAFGYAGHNVILEIQSTIPSTPEKPSKVSMWRG 244
A V++ F I ++G I F Y + ++ + ++PS+
Sbjct: 293 AWEKVKFYIDVKK-----FPI--SIGIIVFSYTSQIFLPSLEGNM----QQPSEFHC--- 338
Query: 245 MIIAYLVVALCYFP--VTIFGYRAFGNSVDDNILLSLEKPRWLIIAANIFVVVHVVGSYQ 302
++ + +A C + Y + + + I +L P + NIF+V + SY
Sbjct: 339 -MMNWTHIAACVLKGLFALVAYLTWADETKEVITDNL--PGSIRAVVNIFLVAKALLSYP 395
Query: 303 VYAVPVFHMLESFLAEKMN--FKPSRF--------LRFAIRNLYVSITMVLAITFPFFGG 352
+ +LE L ++ + F P+ + +R V T+++AI P F
Sbjct: 396 LPFFAAVEVLEKSLFQEGSRAFFPACYGGDGRLKSWGLTLRCALVVFTLLMAIYVPHFAL 455
Query: 353 LLSFFGGFVFAPTTYFLPCIMWIFIYKPKL 382
L+ G A + LP + + + KL
Sbjct: 456 LMGLTGSLTGAGLCFLLPSLFHLRLLWRKL 485
>VIAA_HUMAN (Q9H598) Vesicular inhibitory amino acid transporter
(GABA and glycine transporter) (Vesicular GABA
transporter) (hVIAAT)
Length = 525
Score = 35.4 bits (80), Expect = 0.26
Identities = 84/390 (21%), Positives = 157/390 (39%), Gaps = 47/390 (12%)
Query: 17 YSAFHNVT-AMVGAAVLGFPYAMSQLGWGLGITILVLSWICTLYTAWQMIEM--HESVSG 73
+ A NVT A+ G VLG PYA+ G+ LG+ +++ + + YT +I E+ G
Sbjct: 119 WEAGWNVTNAIQGMFVLGLPYAILHGGY-LGLFLIIFAAVVCCYTGKILIACLYEENEDG 177
Query: 74 KRF---DKYHELSQHAFGER---LGLWIVVPQQLMVEVGIDIVYMVIGAKSLKKLHEILC 127
+ D Y ++ R LG +V Q++ V I+Y+V+ + L
Sbjct: 178 EVVRVRDSYVAIANACCAPRFPTLGGRVVNVAQIIELVMTCILYVVVSGNLMYNSFPGL- 236
Query: 128 DDCEPIKTTYFIVLFAFVQYVLSHLPSFNSVAGISLVA--AAMSLSYSTIAWIASIHRG- 184
P+ + ++ V + L + +V+ SL+ A ++ IA+ S R
Sbjct: 237 ----PVSQKSWSIIATAVLLPCAFLKNLKAVSKFSLLCTLAHFVINILVIAYCLSRARDW 292
Query: 185 ALPDVQYSSRYSTKAGNIFGIFNALGDIAFGYAGHNVILEIQSTIPSTPEKPSKVSMWRG 244
A V++ F I ++G I F Y + ++ + ++PS+
Sbjct: 293 AWEKVKFYIDVKK-----FPI--SIGIIVFSYTSQIFLPSLEGNM----QQPSEFHC--- 338
Query: 245 MIIAYLVVALCYFP--VTIFGYRAFGNSVDDNILLSLEKPRWLIIAANIFVVVHVVGSYQ 302
++ + +A C + Y + + + I +L P + NIF+V + SY
Sbjct: 339 -MMNWTHIAACVLKGLFALVAYLTWADETKEVITDNL--PGSIRAVVNIFLVAKALLSYP 395
Query: 303 VYAVPVFHMLESFLAEKMN--FKPSRFLR--------FAIRNLYVSITMVLAITFPFFGG 352
+ +LE L ++ + F P+ + +R V T+++AI P F
Sbjct: 396 LPFFAAVEVLEKSLFQEGSRAFFPACYSGDGRLKSWGLTLRCALVVFTLLMAIYVPHFAL 455
Query: 353 LLSFFGGFVFAPTTYFLPCIMWIFIYKPKL 382
L+ G A + LP + + + KL
Sbjct: 456 LMGLTGSLTGAGLCFLLPSLFHLRLLWRKL 485
>AVT2_YEAST (P39981) Vacuolar amino acid transporter 2
Length = 480
Score = 35.4 bits (80), Expect = 0.26
Identities = 72/368 (19%), Positives = 142/368 (38%), Gaps = 28/368 (7%)
Query: 19 AFHNVT-AMVGAAVLGFPYAMSQLGWGLGITILVLSWICTLYTAWQMIEMHESVSGKRFD 77
AF N+ +++GA ++ P+A+ G G+ V +T ++I ++ +++GKR
Sbjct: 72 AFMNLANSILGAGIITQPFAIKNAGILGGLLSYVALGFIVDWTL-RLIVINLTLAGKR-- 128
Query: 78 KYHELSQHAFGERLGLWIVVPQQLMVEVGIDIVYMVIGAKSLKKLHEILCDDCEPI---- 133
Y +H G++ L I+ L G ++IG L I + +
Sbjct: 129 TYQGTVEHVMGKKGKLLILFTNGLFAFGGCIGYCIIIGDTIPHVLRAIFSQNDGNVHFWL 188
Query: 134 -KTTYFIVLFAFVQYVLSHLPSFNSVAGISLVAAAMSLSYSTIAWIASIHRGALPDVQYS 192
+ +++ F+ + LS + +++ S +A + I + + RG + +
Sbjct: 189 RRNVIIVMVTTFISFPLSMKRNIEALSKASFLAVISMI----IIVLTVVIRGPMLPYDWK 244
Query: 193 SRYSTKAGNIF---GIFNALGDIAFGYAGHNVILEIQSTIPSTPEKPSKVSMWRGMIIAY 249
+S K + F IF +L I+F H+ S I + S R I+
Sbjct: 245 G-HSLKLSDFFMKATIFRSLSVISFALVCHHNT----SFIFFSMRNRSVAKFTRLTHISI 299
Query: 250 LVVALCYFPVTIFGYRAFGNSVDDNILLSLEKPRWLIIAANIFVVVHVVGSYQVYAVPVF 309
++ +C + G+ F N+L S I A + +++ ++ + +
Sbjct: 300 IISVICCALMGYSGFAVFKEKTKGNVLNSFPGTDTAINIARLCFGFNMLTTFPMEIFVLR 359
Query: 310 HMLESFLAEKMNFKP-------SRFLRFAIRNLYVSITMVLAITFPFFGGLLSFFGGFVF 362
++ + L E K S I + V ITM +++T G L G
Sbjct: 360 DVVGNLLHECNLIKNYDEHTQLSGKQHVVITSSLVFITMGISLTTCNLGALFELIGATTA 419
Query: 363 APTTYFLP 370
+ Y LP
Sbjct: 420 STMAYILP 427
>VIAA_MOUSE (O35633) Vesicular inhibitory amino acid transporter
(GABA and glycine transporter) (Vesicular GABA
transporter) (mVIAAT) (mVGAT)
Length = 525
Score = 34.7 bits (78), Expect = 0.45
Identities = 83/390 (21%), Positives = 157/390 (39%), Gaps = 47/390 (12%)
Query: 17 YSAFHNVT-AMVGAAVLGFPYAMSQLGWGLGITILVLSWICTLYTAWQMIEM--HESVSG 73
+ A NVT A+ G VLG PYA+ G+ LG+ +++ + + YT +I E+ G
Sbjct: 119 WEAGWNVTNAIQGMFVLGLPYAILHGGY-LGLFLIIFAAVVCCYTGKILIACLYEENEDG 177
Query: 74 KRF---DKYHELSQHAFGER---LGLWIVVPQQLMVEVGIDIVYMVIGAKSLKKLHEILC 127
+ D Y ++ R LG +V Q++ V I+Y+V+ + L
Sbjct: 178 EVVRVRDSYVAIANACCAPRFPTLGGRVVNVAQIIELVMTCILYVVVSGNLMYNSFPGL- 236
Query: 128 DDCEPIKTTYFIVLFAFVQYVLSHLPSFNSVAGISLVA--AAMSLSYSTIAWIASIHRG- 184
P+ + ++ V + L + +V+ SL+ A ++ IA+ S R
Sbjct: 237 ----PVSQKSWSIIATAVLLPCAFLKNLKAVSKFSLLCTLAHFVINILVIAYCLSRARDW 292
Query: 185 ALPDVQYSSRYSTKAGNIFGIFNALGDIAFGYAGHNVILEIQSTIPSTPEKPSKVSMWRG 244
A V++ F I ++G I F Y + ++ + ++PS+
Sbjct: 293 AWEKVKFYIDVKK-----FPI--SIGIIVFSYTSQIFLPSLEGNM----QQPSEFHC--- 338
Query: 245 MIIAYLVVALCYFP--VTIFGYRAFGNSVDDNILLSLEKPRWLIIAANIFVVVHVVGSYQ 302
++ + +A C + Y + + + I +L P + N+F+V + SY
Sbjct: 339 -MMNWTHIAACVLKGLFALVAYLTWADETKEVITDNL--PGSIRAVVNLFLVAKALLSYP 395
Query: 303 VYAVPVFHMLESFLAEKMN--FKPSRF--------LRFAIRNLYVSITMVLAITFPFFGG 352
+ +LE L ++ + F P+ + +R V T+++AI P F
Sbjct: 396 LPFFAAVEVLEKSLFQEGSRAFFPACYGGDGRLKSWGLTLRCALVVFTLLMAIYVPHFAL 455
Query: 353 LLSFFGGFVFAPTTYFLPCIMWIFIYKPKL 382
L+ G A + LP + + + KL
Sbjct: 456 LMGLTGSLTGAGLCFLLPSLFHLRLLWRKL 485
Database: sprot
Posted date: Nov 25, 2004 10:54 AM
Number of letters in database: 59,974,054
Number of sequences in database: 164,201
Lambda K H
0.329 0.141 0.447
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 46,251,206
Number of Sequences: 164201
Number of extensions: 1884561
Number of successful extensions: 5836
Number of sequences better than 10.0: 40
Number of HSP's better than 10.0 without gapping: 11
Number of HSP's successfully gapped in prelim test: 29
Number of HSP's that attempted gapping in prelim test: 5802
Number of HSP's gapped (non-prelim): 50
length of query: 403
length of database: 59,974,054
effective HSP length: 112
effective length of query: 291
effective length of database: 41,583,542
effective search space: 12100810722
effective search space used: 12100810722
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.8 bits)
S2: 67 (30.4 bits)
Medicago: description of AC135505.15