BLAST2 result
BLASTP 2.2.2 [Dec-14-2001]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= AC135232.5 + phase: 0
(812 letters)
Database: sprot
164,201 sequences; 59,974,054 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
RIR1_HUMAN (P23921) Ribonucleoside-diphosphate reductase M1 chai... 1126 0.0
RIR1_MOUSE (P07742) Ribonucleoside-diphosphate reductase M1 chai... 1120 0.0
RIR1_BRARE (P79732) Ribonucleoside-diphosphate reductase M1 chai... 1116 0.0
RIR1_NEUCR (Q9UW15) Ribonucleoside-diphosphate reductase large c... 1088 0.0
RIR1_DROME (P48591) Ribonucleoside-diphosphate reductase M1 chai... 1086 0.0
RIR1_SCHPO (P36602) Ribonucleoside-diphosphate reductase large c... 1079 0.0
RIR1_CAEEL (Q03604) Ribonucleoside-diphosphate reductase large c... 1059 0.0
RIR1_YEAST (P21524) Ribonucleoside-diphosphate reductase large c... 1053 0.0
RIR3_YEAST (P21672) Ribonucleoside-diphosphate reductase large c... 1035 0.0
RIR1_PLAF4 (P50648) Ribonucleoside-diphosphate reductase large c... 1024 0.0
RIR1_VARV (P32984) Ribonucleoside-diphosphate reductase large ch... 1009 0.0
RIR1_VACCV (P12848) Ribonucleoside-diphosphate reductase large c... 1009 0.0
RIR1_VACCC (P20503) Ribonucleoside-diphosphate reductase large c... 1009 0.0
RIR1_CRYPV (O61065) Ribonucleoside-diphosphate reductase large c... 1004 0.0
RIR1_PLAFG (P50647) Ribonucleoside-diphosphate reductase large c... 984 0.0
RIR1_TRYBB (O15909) Ribonucleoside-diphosphate reductase large c... 952 0.0
RIR1_ENCCU (Q8SR37) Ribonucleoside-diphosphate reductase large c... 810 0.0
RIR1_ASFB7 (P42491) Ribonucleoside-diphosphate reductase large c... 515 e-145
RIR1_ASFM2 (P26685) Ribonucleoside-diphosphate reductase large c... 508 e-143
RIR1_CHLTR (O84834) Ribonucleoside-diphosphate reductase alpha c... 481 e-135
>RIR1_HUMAN (P23921) Ribonucleoside-diphosphate reductase M1 chain
(EC 1.17.4.1) (Ribonucleotide reductase large chain)
Length = 792
Score = 1126 bits (2913), Expect = 0.0
Identities = 542/812 (66%), Positives = 655/812 (79%), Gaps = 20/812 (2%)
Query: 1 MYVVKRDGRQEAVHFDKITARLKKLSYGLSTEHCDPVLVAQKVCAGVYKGVTTSQLDELA 60
M+V+KRDGRQE V FDKIT+R++KL YGL+ + DP + KV G+Y GVTT +LD LA
Sbjct: 1 MHVIKRDGRQERVMFDKITSRIQKLCYGLNMDFVDPAQITMKVIQGLYSGVTTVELDTLA 60
Query: 61 AETAAGMTANHPDYASLAARIAVSNLHKNTLKSFSETVKVMYNHFNHRSGKKAPLIADDV 120
AETAA +T HPDYA LAARIAVSNLHK T K FS+ ++ +YN+ N +GK +P++A
Sbjct: 61 AETAATLTTKHPDYAILAARIAVSNLHKETKKVFSDVMEDLYNYINPHNGKHSPMVAKST 120
Query: 121 YEIIIKNAARLDSEIIYDRDFDYDYFGFKTLERSYLLKVQGVVVERPQHMIMRVSVGIHK 180
+I++ N RL+S IIYDRDF Y+YFGFKTLERSYLLK+ G V ERPQHM+MRVSVGIHK
Sbjct: 121 LDIVLANKDRLNSAIIYDRDFSYNYFGFKTLERSYLLKINGKVAERPQHMLMRVSVGIHK 180
Query: 181 DDVESAVKTYHFMSQRWFTHASPTLFNAGTPRPQLSSCFLVCMKEDSIEGIYDTLKECAV 240
+D+++A++TY+ +S+RWFTHASPTLFNAGT RPQLSSCFL+ MK+DSIEGIYDTLK+CA+
Sbjct: 181 EDIDAAIETYNLLSERWFTHASPTLFNAGTNRPQLSSCFLLSMKDDSIEGIYDTLKQCAL 240
Query: 241 ISKSAGGIGVSVHNIRAHGSYIRGTNGTSNGIVPMLRVFNDTARYVDQGGGKRKGAFAVY 300
ISKSAGGIGV+V IRA GSYI GTNG SNG+VPMLRV+N+TARYVDQGG KR GAFA+Y
Sbjct: 241 ISKSAGGIGVAVSCIRATGSYIAGTNGNSNGLVPMLRVYNNTARYVDQGGNKRPGAFAIY 300
Query: 301 LEPWHADIFEFLELKINHGKEEQRARDLFYALWVPDLFMERVQSNGEWSLFCPNEAPGLA 360
LEPWH DIFEFL+LK N GKEEQRARDLF+ALW+PDLFM+RV++N +WSL CPNE PGL
Sbjct: 301 LEPWHLDIFEFLDLKKNTGKEEQRARDLFFALWIPDLFMKRVETNQDWSLMCPNECPGLD 360
Query: 361 DCWGEEYDKLYTQYEKAGKAKKIVQAQSLWFAILKSQIETGNPYMLFKDACNRKSNQQNL 420
+ WGEE++KLY YEK G+ +K+V+AQ LW+AI++SQ ETG PYML+KD+CNRKSNQQNL
Sbjct: 361 EVWGEEFEKLYASYEKQGRVRKVVKAQQLWYAIIESQTETGTPYMLYKDSCNRKSNQQNL 420
Query: 421 GTIKSSNLCTEIIEYTSPTETAVCNLASIALPRYVRDKGLPVESHQSKLVGSRGSSSRYF 480
GTIK SNLCTEI+EYTS E AVCNLAS+AL YV +S +
Sbjct: 421 GTIKCSNLCTEIVEYTSKDEVAVCNLASLALNMYV-------------------TSEHTY 461
Query: 481 DFEKLGEVTAVVTTNLNKIIDVNYYPVETAERSNLRHRPIGIGVQGLADTFILLGMAFDS 540
DF+KL EVT VV NLNKIID+NYYPV A SN RHRPIGIGVQGLAD FIL+ F+S
Sbjct: 462 DFKKLAEVTKVVVRNLNKIIDINYYPVPEACLSNKRHRPIGIGVQGLADAFILMRYPFES 521
Query: 541 PEAQQLNKDIFETIYYHALKTSCELAAKEGPYETYSGSPVSKGILQPDMWGVTPSNLWDW 600
EAQ LNK IFETIYY AL+ SC+LA ++GPYETY GSPVSKGILQ DMW VTP++LWDW
Sbjct: 522 AEAQLLNKQIFETIYYGALEASCDLAKEQGPYETYEGSPVSKGILQYDMWNVTPTDLWDW 581
Query: 601 GALREMISKTGVRNSLLVAPMPTASTSQILGNNECFEPYTSNIYNRRVLSGEFVVVNKHL 660
L+E I+K G+RNSLL+APMPTAST+QILGNNE EPYTSNIY RRVLSGEF +VN HL
Sbjct: 582 KVLKEKIAKYGIRNSLLIAPMPTASTAQILGNNESIEPYTSNIYTRRVLSGEFQIVNPHL 641
Query: 661 LHDLTEMGLWNPALKNKIIYDNGSVQNLSEIPAELKVIYKTVWEIKQKILVDMAVDRGCY 720
L DLTE GLW+ +KN+II NGS+Q++ EIP +LK +YKTVWEI QK ++ MA +RG +
Sbjct: 642 LKDLTERGLWHEEMKNQIIACNGSIQSIPEIPDDLKQLYKTVWEISQKTVLKMAAERGAF 701
Query: 721 IDQSQSLNIHMDKPNFGKLTSLHFYAWSKGLKTGMYYLRTRAASDAIKFTVDTSAIKDQP 780
IDQSQSLNIH+ +PN+GKLTS+HFY W +GLKTGMYYLRTR A++ I+FT++ +KD+
Sbjct: 702 IDQSQSLNIHIAEPNYGKLTSMHFYGWKQGLKTGMYYLRTRPAANPIQFTLNKEKLKDKE 761
Query: 781 KVKEADDEDDDTKMAQMVCSLTNRDECEACGS 812
KV + ++E+ + A MVCSL NRDEC CGS
Sbjct: 762 KVSK-EEEEKERNTAAMVCSLENRDECLMCGS 792
>RIR1_MOUSE (P07742) Ribonucleoside-diphosphate reductase M1 chain
(EC 1.17.4.1) (Ribonucleotide reductase large chain)
Length = 792
Score = 1120 bits (2898), Expect = 0.0
Identities = 537/812 (66%), Positives = 651/812 (80%), Gaps = 20/812 (2%)
Query: 1 MYVVKRDGRQEAVHFDKITARLKKLSYGLSTEHCDPVLVAQKVCAGVYKGVTTSQLDELA 60
M+V+KRDGRQE V FDKIT+R++KL YGL+ + DP + KV G+Y GVTT +LD LA
Sbjct: 1 MHVIKRDGRQERVMFDKITSRIQKLCYGLNMDFVDPAQITMKVIQGLYSGVTTVELDTLA 60
Query: 61 AETAAGMTANHPDYASLAARIAVSNLHKNTLKSFSETVKVMYNHFNHRSGKKAPLIADDV 120
AETAA +T HPDYA LAARIAVSNLHK T K FS+ ++ +YN+ N +G+ +P++A
Sbjct: 61 AETAATLTTKHPDYAILAARIAVSNLHKETKKVFSDVMEDLYNYINPHNGRHSPMVASST 120
Query: 121 YEIIIKNAARLDSEIIYDRDFDYDYFGFKTLERSYLLKVQGVVVERPQHMIMRVSVGIHK 180
+I++ N RL+S IIYDRDF Y+YFGFKTLERSYLLK+ G V ERPQHM+MRVSVGIHK
Sbjct: 121 LDIVMANKDRLNSAIIYDRDFSYNYFGFKTLERSYLLKINGKVAERPQHMLMRVSVGIHK 180
Query: 181 DDVESAVKTYHFMSQRWFTHASPTLFNAGTPRPQLSSCFLVCMKEDSIEGIYDTLKECAV 240
+D+++A++TY+ +S++WFTHA PTLFNAGT RPQLSSCFL+ MK+DSIEGIYDTLK+CA+
Sbjct: 181 EDIDAAIETYNLLSEKWFTHAPPTLFNAGTNRPQLSSCFLLSMKDDSIEGIYDTLKQCAL 240
Query: 241 ISKSAGGIGVSVHNIRAHGSYIRGTNGTSNGIVPMLRVFNDTARYVDQGGGKRKGAFAVY 300
ISKSAGGIGV+V IRA GSYI GTNG SNG+VPMLRV+N+TARYVDQGG KR GAFA+Y
Sbjct: 241 ISKSAGGIGVAVSCIRATGSYIAGTNGNSNGLVPMLRVYNNTARYVDQGGNKRPGAFAIY 300
Query: 301 LEPWHADIFEFLELKINHGKEEQRARDLFYALWVPDLFMERVQSNGEWSLFCPNEAPGLA 360
LEPWH DIFEFL+LK N GKEEQRARDLF+ALW+PDLFM+RV++N +WSL CPNE PGL
Sbjct: 301 LEPWHLDIFEFLDLKKNTGKEEQRARDLFFALWIPDLFMKRVETNQDWSLMCPNECPGLD 360
Query: 361 DCWGEEYDKLYTQYEKAGKAKKIVQAQSLWFAILKSQIETGNPYMLFKDACNRKSNQQNL 420
+ WGEE++KLY YEK G+ +K+V+AQ LW+AI++SQ ETG PYML+KD+CNRKSNQQNL
Sbjct: 361 EVWGEEFEKLYESYEKQGRVRKVVKAQQLWYAIIESQTETGTPYMLYKDSCNRKSNQQNL 420
Query: 421 GTIKSSNLCTEIIEYTSPTETAVCNLASIALPRYVRDKGLPVESHQSKLVGSRGSSSRYF 480
GTIK SNLCTEI+EYTS E AVCNLAS+AL YV + +
Sbjct: 421 GTIKCSNLCTEIVEYTSKDEVAVCNLASLALNMYV-------------------TPEHTY 461
Query: 481 DFEKLGEVTAVVTTNLNKIIDVNYYPVETAERSNLRHRPIGIGVQGLADTFILLGMAFDS 540
DFEKL EVT V+ NLNKIID+NYYP+ A SN RHRPIGIGVQGLAD FIL+ F+S
Sbjct: 462 DFEKLAEVTKVIVRNLNKIIDINYYPIPEAHLSNKRHRPIGIGVQGLADAFILMRYPFES 521
Query: 541 PEAQQLNKDIFETIYYHALKTSCELAAKEGPYETYSGSPVSKGILQPDMWGVTPSNLWDW 600
PEAQ LNK IFETIYY AL+ SCELA + GPYETY GSPVSKGILQ DMW V P++LWDW
Sbjct: 522 PEAQLLNKQIFETIYYGALEASCELAKEYGPYETYEGSPVSKGILQYDMWNVAPTDLWDW 581
Query: 601 GALREMISKTGVRNSLLVAPMPTASTSQILGNNECFEPYTSNIYNRRVLSGEFVVVNKHL 660
L+E I+K G+RNSLL+APMPTAST+QILGNNE EPYTSNIY RRVLSGEF +VN HL
Sbjct: 582 KPLKEKIAKYGIRNSLLIAPMPTASTAQILGNNESIEPYTSNIYTRRVLSGEFQIVNPHL 641
Query: 661 LHDLTEMGLWNPALKNKIIYDNGSVQNLSEIPAELKVIYKTVWEIKQKILVDMAVDRGCY 720
L DLTE GLWN +KN+II NGS+Q++ EIP +LK +YKTVWEI QK ++ MA +RG +
Sbjct: 642 LKDLTERGLWNKEMKNQIIACNGSIQSIPEIPDDLKQLYKTVWEISQKTVLKMAAERGAF 701
Query: 721 IDQSQSLNIHMDKPNFGKLTSLHFYAWSKGLKTGMYYLRTRAASDAIKFTVDTSAIKDQP 780
IDQSQSLNIH+ +PN+GKLTS+HFY W +GLKTGMYYLRTR A++ I+FT++ +KD+
Sbjct: 702 IDQSQSLNIHIAEPNYGKLTSMHFYGWKQGLKTGMYYLRTRPAANPIQFTLNKEKLKDKE 761
Query: 781 KVKEADDEDDDTKMAQMVCSLTNRDECEACGS 812
K + ++E+ + A MVCSL NR+EC CGS
Sbjct: 762 KALK-EEEEKERNTAAMVCSLENREECLMCGS 792
>RIR1_BRARE (P79732) Ribonucleoside-diphosphate reductase M1 chain
(EC 1.17.4.1) (Ribonucleotide reductase protein R1 class
I)
Length = 794
Score = 1116 bits (2887), Expect = 0.0
Identities = 538/813 (66%), Positives = 651/813 (79%), Gaps = 20/813 (2%)
Query: 1 MYVVKRDGRQEAVHFDKITARLKKLSYGLSTEHCDPVLVAQKVCAGVYKGVTTSQLDELA 60
M+V+KRDG QE V FDKIT+R++KL YGL+++ DP + KV G+Y GVTT +LD LA
Sbjct: 1 MHVIKRDGGQEGVMFDKITSRIQKLCYGLNSDFVDPTQITMKVIQGLYSGVTTVELDTLA 60
Query: 61 AETAAGMTANHPDYASLAARIAVSNLHKNTLKSFSETVKVMYNHFNHRSGKKAPLIADDV 120
AETAA T HPDYA LAARIAVSNLHK T K FSE ++ +YN+ N + + +P+I+ +
Sbjct: 61 AETAATSTTKHPDYAILAARIAVSNLHKETKKVFSEVMEDLYNYVNPLNSRHSPMISKET 120
Query: 121 YEIIIKNAARLDSEIIYDRDFDYDYFGFKTLERSYLLKVQGVVVERPQHMIMRVSVGIHK 180
+I++ N RL+S IIYDRDF Y++FGFKTLERSYLLK+ G V ERPQHM+MRVSVGIHK
Sbjct: 121 LDIVLANKDRLNSAIIYDRDFSYNFFGFKTLERSYLLKINGKVAERPQHMLMRVSVGIHK 180
Query: 181 DDVESAVKTYHFMSQRWFTHASPTLFNAGTPRPQLSSCFLVCMKEDSIEGIYDTLKECAV 240
+D+ +A++TY+ +S++WFTHASPTLFNAGT RPQLSSCFL+ MK+DSIEGIYDTLK+CA+
Sbjct: 181 EDIAAAIETYNLLSEKWFTHASPTLFNAGTNRPQLSSCFLLAMKDDSIEGIYDTLKQCAL 240
Query: 241 ISKSAGGIGVSVHNIRAHGSYIRGTNGTSNGIVPMLRVFNDTARYVDQGGGKRKGAFAVY 300
ISKSAGGIGV+V IRA G YI GTNG SNG+VPMLRV N+TARYVDQGG KR GAFA+Y
Sbjct: 241 ISKSAGGIGVAVSCIRATGRYIAGTNGNSNGLVPMLRVNNNTARYVDQGGNKRPGAFAMY 300
Query: 301 LEPWHADIFEFLELKINHGKEEQRARDLFYALWVPDLFMERVQSNGEWSLFCPNEAPGLA 360
LEPWH DIF+FLELK N GKEEQRARDLFYALW+PDLFM+RV++NG+WSL CPN+ PGL
Sbjct: 301 LEPWHFDIFDFLELKKNTGKEEQRARDLFYALWIPDLFMKRVETNGDWSLMCPNDCPGLD 360
Query: 361 DCWGEEYDKLYTQYEKAGKAKKIVQAQSLWFAILKSQIETGNPYMLFKDACNRKSNQQNL 420
+CWGEE++KLY +YE+ G+AK++V+AQ LW+AI++SQ ETG PYML+KDACNRKSN+QNL
Sbjct: 361 ECWGEEFEKLYAKYEQEGRAKRVVKAQQLWYAIIESQTETGTPYMLYKDACNRKSNRQNL 420
Query: 421 GTIKSSNLCTEIIEYTSPTETAVCNLASIALPRYVRDKGLPVESHQSKLVGSRGSSSRYF 480
GTIK SNLCTEI+EYTS E AVCNLASIAL YV +S R F
Sbjct: 421 GTIKCSNLCTEIVEYTSADEVAVCNLASIALNMYV-------------------TSERTF 461
Query: 481 DFEKLGEVTAVVTTNLNKIIDVNYYPVETAERSNLRHRPIGIGVQGLADTFILLGMAFDS 540
DF+KL VT V+ NLNKIID+NYYPV+ AE SN RHRPIGIGVQGLAD FIL+ F+S
Sbjct: 462 DFQKLASVTKVIVKNLNKIIDINYYPVKEAENSNKRHRPIGIGVQGLADAFILMRFPFES 521
Query: 541 PEAQQLNKDIFETIYYHALKTSCELAAKEGPYETYSGSPVSKGILQPDMWGVTPSNLWDW 600
EAQ LN IFETIYY AL++SCELAA+ GPY+TY+G PVSKGILQ DMW TP++LWDW
Sbjct: 522 TEAQLLNTQIFETIYYAALESSCELAAEYGPYQTYAGCPVSKGILQYDMWEKTPTDLWDW 581
Query: 601 GALREMISKTGVRNSLLVAPMPTASTSQILGNNECFEPYTSNIYNRRVLSGEFVVVNKHL 660
AL+E I+ GVRNSLL+APMPTAST+QILGNNE EPYTSNIY+RRVLSGEF +VN HL
Sbjct: 582 AALKEKIANDGVRNSLLLAPMPTASTAQILGNNESIEPYTSNIYHRRVLSGEFQIVNPHL 641
Query: 661 LHDLTEMGLWNPALKNKIIYDNGSVQNLSEIPAELKVIYKTVWEIKQKILVDMAVDRGCY 720
L DLTE GLWN +KN+II NGS+Q + IP +LK +YKTVWEI QK ++ MA DRG Y
Sbjct: 642 LKDLTERGLWNEEMKNQIIAQNGSIQTIPAIPDDLKELYKTVWEISQKTILKMAADRGAY 701
Query: 721 IDQSQSLNIHMDKPNFGKLTSLHFYAWSKGLKTGMYYLRTRAASDAIKFTVDTSAIKDQP 780
IDQSQSLNIH+ +PN+GKLTS+HFY W +GLKTGMYYLRT+ ++ I+FT++ +K+
Sbjct: 702 IDQSQSLNIHIAEPNYGKLTSMHFYGWKQGLKTGMYYLRTKPGANPIQFTLNKEKLKETQ 761
Query: 781 KVKEADDED-DDTKMAQMVCSLTNRDECEACGS 812
K ++DE+ + A MVCSL NR EC CGS
Sbjct: 762 KTTSSEDEETKERNKAAMVCSLENRHECLMCGS 794
>RIR1_NEUCR (Q9UW15) Ribonucleoside-diphosphate reductase large
chain (EC 1.17.4.1) (Ribonucleotide reductase large
subunit)
Length = 929
Score = 1088 bits (2815), Expect = 0.0
Identities = 525/777 (67%), Positives = 625/777 (79%), Gaps = 18/777 (2%)
Query: 1 MYVVKRDGRQEAVHFDKITARLKKLSYGLSTEHCDPVLVAQKVCAGVYKGVTTSQLDELA 60
MYV KRDGRQE V FDKITAR+ +L YGL H DPV + QKV +GVY GVTT+QLD+LA
Sbjct: 1 MYVKKRDGRQERVQFDKITARVSRLCYGLDMNHVDPVAITQKVISGVYGGVTTAQLDDLA 60
Query: 61 AETAAGMTANHPDYASLAARIAVSNLHKNTLKSFSETVKVMYNHFNHRSGKKAPLIADDV 120
AETAA MT HPDYA LAARIAVSNLHK T K +S + +YN+ N R+GK +P+IA DV
Sbjct: 61 AETAAYMTVTHPDYAILAARIAVSNLHKQTKKQWSLVISELYNYVNPRTGKHSPMIAKDV 120
Query: 121 YEIIIKNAARLDSEIIYDRDFDYDYFGFKTLERSYLLKVQGVVVERPQHMIMRVSVGIHK 180
YE ++++ DS I+YDRDF+Y YFGFKTLERSYLLK+ G + ERPQHMIMRV+VGI
Sbjct: 121 YECVMRHKDEFDSAIVYDRDFNYQYFGFKTLERSYLLKLDGQIAERPQHMIMRVAVGIWG 180
Query: 181 DDVESAVKTYHFMSQRWFTHASPTLFNAGTPRPQLSSCFLVCMKEDSIEGIYDTLKECAV 240
DDVE ++TY+ MS + FTHASPTLFNAGTP+PQLSSCFLV MKEDSIEGIYDTLK CA+
Sbjct: 181 DDVERVIETYNLMSLKTFTHASPTLFNAGTPQPQLSSCFLVDMKEDSIEGIYDTLKTCAM 240
Query: 241 ISKSAGGIGVSVHNIRAHGSYIRGTNGTSNGIVPMLRVFNDTARYVDQGGGKRKGAFAVY 300
ISK AGGIG+++H IRA GSYI GTNGTSNGIVPMLRVFN+TARYVDQGG KR GAFA+Y
Sbjct: 241 ISKMAGGIGLNIHRIRATGSYIAGTNGTSNGIVPMLRVFNNTARYVDQGGNKRPGAFAIY 300
Query: 301 LEPWHADIFEFLELKINHGKEEQRARDLFYALWVPDLFMERVQSNGEWSLFCPNEAPGLA 360
LEPWHAD+FEFL+L+ NHGKEE RARDLF ALW+PDLFM+RV+ NG+W+L CP+E PGLA
Sbjct: 301 LEPWHADVFEFLDLRKNHGKEEVRARDLFLALWIPDLFMKRVEQNGQWTLMCPHECPGLA 360
Query: 361 DCWGEEYDKLYTQYEKAGKAKKIVQAQSLWFAILKSQIETGNPYMLFKDACNRKSNQQNL 420
D +G+E++ LY +YEK GK +K V+AQ LW+AIL++Q ETGNP+ML+KDACNRKSNQ+NL
Sbjct: 361 DVYGDEFEALYEKYEKEGKGRKTVKAQKLWYAILEAQTETGNPFMLYKDACNRKSNQKNL 420
Query: 421 GTIKSSNLCTEIIEYTSPTETAVCNLASIALPRYVRDKGLPVESHQSKLVGSRGSSSRYF 480
GTI+SSNLCTEIIEY++P E AVCNLAS+AL ++ + +
Sbjct: 421 GTIRSSNLCTEIIEYSAPDEVAVCNLASLALSAFI------------------DYENASY 462
Query: 481 DFEKLGEVTAVVTTNLNKIIDVNYYPVETAERSNLRHRPIGIGVQGLADTFILLGMAFDS 540
DF+KL EVT VV NLNKIID+N+YPV+ A SN+RHRPIG+GVQGLAD F+ L M FDS
Sbjct: 463 DFKKLHEVTQVVVRNLNKIIDINHYPVKEAHNSNMRHRPIGVGVQGLADAFLALRMPFDS 522
Query: 541 PEAQQLNKDIFETIYYHALKTSCELAAKEGPYETYSGSPVSKGILQPDMWGVTPSNLWDW 600
A +LN IFETIY+ AL SC+LA ++GPY TY GSPVS+GILQ DMW VTP+NLWDW
Sbjct: 523 DAASKLNIQIFETIYHAALTASCQLAKEQGPYATYEGSPVSQGILQYDMWNVTPTNLWDW 582
Query: 601 GALREMISKTGVRNSLLVAPMPTASTSQILGNNECFEPYTSNIYNRRVLSGEFVVVNKHL 660
AL+ I K GVRNSLL+APMPTASTSQILGNNECFEPYTSNIY RRVL+GEF VVN L
Sbjct: 583 TALKADIKKYGVRNSLLLAPMPTASTSQILGNNECFEPYTSNIYQRRVLAGEFQVVNPWL 642
Query: 661 LHDLTEMGLWNPALKNKIIYDNGSVQNLSEIPAELKVIYKTVWEIKQKILVDMAVDRGCY 720
L DL EMGLW+ A+KN+II + GS+QN+ IP ++K +YKTVWEI Q+ +V MA DRG +
Sbjct: 643 LRDLVEMGLWSDAMKNRIIAEGGSIQNIQSIPNDIKALYKTVWEISQRTIVKMAADRGAF 702
Query: 721 IDQSQSLNIHMDKPNFGKLTSLHFYAWSKGLKTGMYYLRTRAASDAIKFTVDTSAIK 777
IDQSQSLNIHM +P GK+TS+HF W GLKTGMYYLRT+AA+ I+FTVD A++
Sbjct: 703 IDQSQSLNIHMREPTMGKITSMHFAGWKMGLKTGMYYLRTQAAAQPIQFTVDQEALR 759
>RIR1_DROME (P48591) Ribonucleoside-diphosphate reductase M1 chain
(EC 1.17.4.1) (Ribonucleotide reductase large chain)
Length = 812
Score = 1086 bits (2808), Expect = 0.0
Identities = 522/820 (63%), Positives = 647/820 (78%), Gaps = 27/820 (3%)
Query: 1 MYVVKRDGRQEAVHFDKITARLKKLSYGLSTEHCDPVLVAQKVCAGVYKGVTTSQLDELA 60
+YV+KRDGRQE VHFDKIT+R++KL Y L+ + DPV + +V G+Y GVTT +LD LA
Sbjct: 12 LYVIKRDGRQEEVHFDKITSRIQKLCYNLNMDFVDPVTITLQVINGLYCGVTTQELDNLA 71
Query: 61 AETAAGMTANHPDYASLAARIAVSNLHKNTLKSFSETVKVMYNHFNHRSGKKAPLIADDV 120
AE AAG+T NHPDYA LAARIAVSNLHK T K+FS+ + +YNH N + +K PL+++
Sbjct: 72 AEIAAGLTCNHPDYAILAARIAVSNLHKETKKAFSDVFEDLYNHVNKETNQKVPLVSEFH 131
Query: 121 YEIIIKNAARLDSEIIYDRDFDYDYFGFKTLERSYLLKVQGVVVERPQHMIMRVSVGIHK 180
Y ++ KNA RL+S IIYDRDF Y+YFGFKTLERSYLLK G + ERPQHM+MRV++GIH
Sbjct: 132 YNVVKKNATRLNSSIIYDRDFGYNYFGFKTLERSYLLKRNGKIAERPQHMLMRVAIGIHG 191
Query: 181 DDVESAVKTYHFMSQRWFTHASPTLFNAGTPRPQLSSCFLVCMKEDSIEGIYDTLKECAV 240
+D+++AV+TY+ +S+R+FTHASPTLF A T RPQLSSCFL+ M DSIEGI+ ++++CA+
Sbjct: 192 EDIDAAVETYNLLSERYFTHASPTLFAAATNRPQLSSCFLLTMTADSIEGIFKSVEQCAM 251
Query: 241 ISKSAGGIGVSVHNIRAHGSYIRGTNGTSNGIVPMLRVFNDTARYVDQGGGKRKGAFAVY 300
ISKSAGGIG++VH IRA G+ I GTNGTSNG+VPMLRVFN+ ARYVDQGGGKR GAFA+Y
Sbjct: 252 ISKSAGGIGLNVHCIRAKGTSICGTNGTSNGLVPMLRVFNNVARYVDQGGGKRPGAFAIY 311
Query: 301 LEPWHADIFEFLELKINHGKEEQRARDLFYALWVPDLFMERVQSNGEWSLFCPNEAPGLA 360
LEPWH+D+FEFLELK N GKEE RARDLFYALW+PDLFM+RV++NG+WSL CP++ PGL
Sbjct: 312 LEPWHSDVFEFLELKKNTGKEENRARDLFYALWIPDLFMKRVEANGDWSLMCPHKCPGLH 371
Query: 361 DCWGEEYDKLYTQYEKAGKAKKIVQAQSLWFAILKSQIETGNPYMLFKDACNRKSNQQNL 420
D WG+E++KLY +YE+ G+A + V+AQSLWFAI+++Q+ETGNPYMLFKDACNRKSNQQN+
Sbjct: 372 DVWGDEFEKLYEKYEQEGRANRTVKAQSLWFAIIEAQVETGNPYMLFKDACNRKSNQQNV 431
Query: 421 GTIKSSNLCTEIIEYTSPTETAVCNLASIALPRYVRDKGLPVESHQSKLVGSRGSSSRYF 480
GTIK SNLCTEI+EY++P E AVCNLASIAL +V + + +
Sbjct: 432 GTIKCSNLCTEIVEYSAPDEIAVCNLASIALNMFV-------------------TPEKTY 472
Query: 481 DFEKLGEVTAVVTTNLNKIIDVNYYPVETAERSNLRHRPIGIGVQGLADTFILLGMAFDS 540
DF+KL EVT +VT NLNKIID+NYYP+ A +SNLRHRP+GIG+QG AD IL+ ++S
Sbjct: 473 DFKKLKEVTKIVTKNLNKIIDINYYPLPEARKSNLRHRPVGIGIQGFADALILMRFPYES 532
Query: 541 PEAQQLNKDIFETIYYHALKTSCELAAKEGPYETYSGSPVSKGILQPDMWGVTPSNLWDW 600
EA LN+ IFETIYY AL+ SCELA EGPYETY GSPVSKGILQ DMW P+NLWDW
Sbjct: 533 EEAGLLNQQIFETIYYGALEASCELAQTEGPYETYEGSPVSKGILQYDMWDKVPTNLWDW 592
Query: 601 GALREMISKTGVRNSLLVAPMPTASTSQILGNNECFEPYTSNIYNRRVLSGEFVVVNKHL 660
L+E I GVRNSLLVAPMPTAST+QI+GNNE FEPYT+NIY RRVLSGEF VVN HL
Sbjct: 593 QKLKESIRMHGVRNSLLVAPMPTASTAQIMGNNESFEPYTTNIYTRRVLSGEFQVVNHHL 652
Query: 661 LHDLTEMGLWNPALKNKIIYDNGSVQNLSEIPAELKVIYKTVWEIKQKILVDMAVDRGCY 720
L DLTE+ LW+ +KN+II GS+QN+ IP +++ +YKTVWEI K + MA DRG +
Sbjct: 653 LRDLTELDLWDDDMKNQIISSRGSIQNIETIPPKVRDLYKTVWEISVKSTIKMAADRGAF 712
Query: 721 IDQSQSLNIHMDKPNFGKLTSLHFYAWSKGLKTGMYYLRTRAASDAIKFTVDTS----AI 776
IDQSQS NIH+ +PN+GKLTS+HFY+W GLKTGMYYLRT+ A++AI+FTV+ ++
Sbjct: 713 IDQSQSFNIHVAEPNYGKLTSIHFYSWKAGLKTGMYYLRTKPAANAIQFTVNKKQGAVSM 772
Query: 777 KDQPKVKEAD----DEDDDTKMAQMVCSLTNRDECEACGS 812
Q E +ED + KMA MVCSL N+D C +CGS
Sbjct: 773 NGQNGTAEGSPQKYEEDRERKMADMVCSLENKDACMSCGS 812
>RIR1_SCHPO (P36602) Ribonucleoside-diphosphate reductase large
chain (EC 1.17.4.1) (Ribonucleotide reductase)
Length = 811
Score = 1079 bits (2790), Expect = 0.0
Identities = 520/831 (62%), Positives = 645/831 (77%), Gaps = 39/831 (4%)
Query: 1 MYVVKRDGRQEAVHFDKITARLKKLSYGLSTEHCDPVLVAQKVCAGVYKGVTTSQLDELA 60
M+V KRDGRQE V FDKITAR+ +L YGL ++H DPV + QKV +GVY GVTT +LD LA
Sbjct: 1 MFVYKRDGRQEKVAFDKITARVSRLCYGLDSDHVDPVEITQKVISGVYPGVTTIELDNLA 60
Query: 61 AETAAGMTANHPDYASLAARIAVSNLHKNTLKSFSETVKVMYNHFNHRSGKKAPLIADDV 120
AETAA MT HPDYA LAARIAVSNLHK T K FS V+ ++++ N ++ K AP+I+D +
Sbjct: 61 AETAATMTTKHPDYAILAARIAVSNLHKQTEKVFSTVVQQLHDYVNPKTDKPAPMISDKI 120
Query: 121 YEIIIKNAARLDSEIIYDRDFDYDYFGFKTLERSYLLKVQGVVVERPQHMIMRVSVGIHK 180
Y+I++K+ LDS IIYDRDF Y++FGFKTLERSYLL++ G V ERPQHMIMRV+VGIH
Sbjct: 121 YDIVMKHKDELDSAIIYDRDFTYNFFGFKTLERSYLLRIDGKVAERPQHMIMRVAVGIHG 180
Query: 181 DDVESAVKTYHFMSQRWFTHASPTLFNAGTPRPQLSSCFLVCMKEDSIEGIYDTLKECAV 240
+D+E+A++TY+ MSQR+FTHASPTLFNAGTPRPQLSSCFLV MK+DSIEGIYDTLK CA+
Sbjct: 181 EDIEAAIETYNLMSQRYFTHASPTLFNAGTPRPQLSSCFLVTMKDDSIEGIYDTLKMCAM 240
Query: 241 ISKSAGGIGVSVHNIRAHGSYIRGTNGTSNGIVPMLRVFNDTARYVDQGGGKRKGAFAVY 300
ISK+AGGIG+++HNIRA GSYI GTNGTSNGIVPM+RV+N+TARYVDQGG KR GAFA Y
Sbjct: 241 ISKTAGGIGINIHNIRATGSYIAGTNGTSNGIVPMIRVYNNTARYVDQGGNKRPGAFAAY 300
Query: 301 LEPWHADIFEFLELKINHGKEEQRARDLFYALWVPDLFMERVQSNGEWSLFCPNEAPGLA 360
LEPWHAD+ +FLEL+ HG E+ RAR++FYALW+PDLFM+RV+ N +W+ FCPNEAPGLA
Sbjct: 301 LEPWHADVMDFLELRKTHGNEDFRAREMFYALWIPDLFMQRVERNEQWTFFCPNEAPGLA 360
Query: 361 DCWGEEYDKLYTQYEKAGKAKKIVQAQSLWFAILKSQIETGNPYMLFKDACNRKSNQQNL 420
D WG+E+ LY +YEK + ++ + AQ +W+AIL+SQ+ETGNP+ML+KD+CNRKSNQ+N+
Sbjct: 361 DVWGDEFVALYEKYEKENRGRRSLPAQKVWYAILQSQVETGNPFMLYKDSCNRKSNQKNV 420
Query: 421 GTIKSSNLCTEIIEYTSPTETAVCNLASIALPRYVRDKGLPVESHQSKLVGSRGSSSRYF 480
GTI+ SNLCTEI+EY+SP E AVCNLAS+ALP +++D +
Sbjct: 421 GTIRCSNLCTEIVEYSSPDEVAVCNLASVALPTFIKD--------------------GKY 460
Query: 481 DFEKLGEVTAVVTTNLNKIIDVNYYPVETAERSNLRHRPIGIGVQGLADTFILLGMAFDS 540
+F+KL +V VVT NLNKIIDVNYYPV A RSN+RHRP+G+GVQGLAD F L + F+S
Sbjct: 461 NFQKLHDVVKVVTRNLNKIIDVNYYPVPEARRSNMRHRPVGLGVQGLADAFFALRLPFES 520
Query: 541 PEAQQLNKDIFETIYYHALKTSCELAAKEGPYETYSGSPVSKGILQPDMWGVTPSNLWDW 600
A++LN IFETIY+ AL+ SCE+A EG YE+Y GSP S+GILQ DMW V P++LWDW
Sbjct: 521 AGAKKLNIQIFETIYHAALEASCEIAQVEGTYESYEGSPASQGILQYDMWNVNPTDLWDW 580
Query: 601 GALREMISKTGVRNSLLVAPMPTASTSQILGNNECFEPYTSNIYNRRVLSGEFVVVNKHL 660
L+E I+K G+RNSLLVAPMPTASTSQILG NECFEPYTSN+Y RRVLSGEF +VN L
Sbjct: 581 AELKEKIAKHGIRNSLLVAPMPTASTSQILGFNECFEPYTSNMYQRRVLSGEFQIVNPWL 640
Query: 661 LHDLTEMGLWNPALKNKIIYDNGSVQNLSEIPAELKVIYKTVWEIKQKILVDMAVDRGCY 720
L DL E LWN +KNK++ +GS+Q + EIP +LK +YKTVWEI QK ++D A DRG +
Sbjct: 641 LKDLVERDLWNEDMKNKLVMLDGSIQAIPEIPQDLKDLYKTVWEISQKTVIDYAADRGPF 700
Query: 721 IDQSQSLNIHMDKPNFGKLTSLHFYAWSKGLKTGMYYLRTRAASDAIKFTVDTSAIK--- 777
IDQSQSLNIH+ P++GK+TS+HFY W KGLKTGMYYLRT AAS AIKFTVD A++
Sbjct: 701 IDQSQSLNIHLKDPSYGKITSMHFYGWKKGLKTGMYYLRTMAASAAIKFTVDPVALRARN 760
Query: 778 -------DQPKVKE---------ADDEDDDTKMAQMVCSLTNRDECEACGS 812
+P +K +E D + CS+ N + CE C +
Sbjct: 761 EESNEENKKPVIKNGKAEISAEPTKEEIDIYNEKVLACSIKNPEACEMCSA 811
>RIR1_CAEEL (Q03604) Ribonucleoside-diphosphate reductase large
chain (EC 1.17.4.1) (Ribonucleotide reductase)
Length = 788
Score = 1059 bits (2739), Expect = 0.0
Identities = 516/793 (65%), Positives = 627/793 (78%), Gaps = 25/793 (3%)
Query: 2 YVVKRDGRQEAVHFDKITARLKKLSYGLSTEHCDPVLVAQKVCAGVYKGVTTSQLDELAA 61
YVVKRDGR+E VHFDKIT+R++KLSYGL+ + DPV VA KV +G+YKGVTT +LD LAA
Sbjct: 8 YVVKRDGRKEDVHFDKITSRIQKLSYGLNMDFVDPVAVAIKVISGLYKGVTTVELDNLAA 67
Query: 62 ETAAGMTANHPDYASLAARIAVSNLHKNTLKSFSETVKVMYNHFNHRSGKKAPLIADDVY 121
ETAA MT HP+YA LAARIAVSNLHK T K FSE +K ++ + +GK AP+I+D+ +
Sbjct: 68 ETAASMTTQHPEYALLAARIAVSNLHKKTNKVFSEVMKTLHEFHHPHTGKHAPMISDETW 127
Query: 122 EIIIKNAARLDSEIIYDRDFDYDYFGFKTLERSYLLKVQGVVVERPQHMIMRVSVGIHKD 181
II KNA +L+S I+YDRD+ Y YFGFKTLERSYLLK+ +VERPQ M+MRVS+GIH D
Sbjct: 128 AIIEKNADKLNSAIVYDRDYSYTYFGFKTLERSYLLKINKEIVERPQQMLMRVSIGIHGD 187
Query: 182 DVESAVKTYHFMSQRWFTHASPTLFNAGTPRPQLSSCFLVCMKEDSIEGIYDTLKECAVI 241
D+ SA++TY+ MS+R+ THASPTLFN+GT RPQ+SSCFL+ M EDSI GIYDTLK+CA+I
Sbjct: 188 DITSAIETYNLMSERYMTHASPTLFNSGTCRPQMSSCFLLTMSEDSILGIYDTLKQCALI 247
Query: 242 SKSAGGIGVSVHNIRAHGSYIRGTNGTSNGIVPMLRVFNDTARYVDQGGGKRKGAFAVYL 301
SKSAGGIG++VH IRA GS I GTNGTSNG++PMLRV+N+TARYVDQGG KR GAFA+YL
Sbjct: 248 SKSAGGIGLNVHKIRATGSVIAGTNGTSNGLIPMLRVYNNTARYVDQGGNKRPGAFAIYL 307
Query: 302 EPWHADIFEFLELKINHGKEEQRARDLFYALWVPDLFMERVQSNGEWSLFCPNEAPGLAD 361
EPWHADIFEF+ L+ N G EE+RARDLF ALW+PDLFM+RV+ + EWSL CP E PGL D
Sbjct: 308 EPWHADIFEFVSLRKNTGPEEERARDLFLALWIPDLFMKRVEKDQEWSLMCPCECPGLDD 367
Query: 362 CWGEEYDKLYTQYEKAGKAKKIVQAQSLWFAILKSQIETGNPYMLFKDACNRKSNQQNLG 421
CWGEE++ LY +YE G+ +K V+A+ LW I+ +QIETG PY+ +KDA NRKSNQQNLG
Sbjct: 368 CWGEEFEALYAKYEAEGRVRKTVKARKLWEHIVSNQIETGLPYITYKDAANRKSNQQNLG 427
Query: 422 TIKSSNLCTEIIEYTSPTETAVCNLASIALPRYVRDKGLPVESHQSKLVGSRGSSSRYFD 481
TIK SNLCTEIIEY++P E AVCNLASIAL RYV + + FD
Sbjct: 428 TIKCSNLCTEIIEYSAPDEIAVCNLASIALNRYV-------------------TPEKKFD 468
Query: 482 FEKLGEVTAVVTTNLNKIIDVNYYPVETAERSNLRHRPIGIGVQGLADTFILLGMAFDSP 541
F KL EVT V+T NLNKIIDVNYYPVE A SN+RHRPIG+GVQGLAD F+L+ F S
Sbjct: 469 FVKLAEVTKVITRNLNKIIDVNYYPVEEARNSNMRHRPIGLGVQGLADCFMLMRYPFTSA 528
Query: 542 EAQQLNKDIFETIYYHALKTSCELAAKEGPYETYSGSPVSKGILQPDMWGVTPSNLWDWG 601
EA+ LNK IFETIYY AL+ SCELA GPY TY GSPVSKG LQ DMWGVTP++ DW
Sbjct: 529 EARDLNKRIFETIYYAALEASCELAELNGPYSTYEGSPVSKGQLQFDMWGVTPTDQCDWA 588
Query: 602 ALREMISKTGVRNSLLVAPMPTASTSQILGNNECFEPYTSNIYNRRVLSGEFVVVNKHLL 661
LR+ I+K G+RNSLL+APMPTAST+QILGNNE EPYTSNIY+RRVLSG+F +VN H+L
Sbjct: 589 TLRKKIAKHGIRNSLLMAPMPTASTAQILGNNESIEPYTSNIYSRRVLSGDFQIVNPHML 648
Query: 662 HDLTEMGLWNPALKNKIIYDNGSVQNLSEIPAELKVIYKTVWEIKQKILVDMAVDRGCYI 721
DL E GLW +KN++I +NGS+QN+ IP+++K +Y+TVWEI QK +++MA DRG YI
Sbjct: 649 KDLVERGLWTDEMKNRLIANNGSIQNIDGIPSDIKELYRTVWEISQKDIIEMAADRGAYI 708
Query: 722 DQSQSLNIHMDKPNFGKLTSLHFYAWSKGLKTGMYYLRTRAASDAIKFTVDTSAIKDQPK 781
DQSQSLNIHM KP++ +TS+HFY W KGLKTGMYYLRT+ A +A++FTVD +A+K +
Sbjct: 709 DQSQSLNIHMAKPSYAGITSMHFYGWKKGLKTGMYYLRTKPAVNAVQFTVDKNALKTNQQ 768
Query: 782 ------VKEADDE 788
V E+ DE
Sbjct: 769 AETPATVAESQDE 781
>RIR1_YEAST (P21524) Ribonucleoside-diphosphate reductase large
chain 1 (EC 1.17.4.1) (Ribonucleotide reductase)
Length = 888
Score = 1053 bits (2723), Expect = 0.0
Identities = 504/786 (64%), Positives = 627/786 (79%), Gaps = 16/786 (2%)
Query: 1 MYVVKRDGRQEAVHFDKITARLKKLSYGLSTEHCDPVLVAQKVCAGVYKGVTTSQLDELA 60
MYV KRDGR+E V FDKITAR+ +L YGL +H D V V Q++ +GVY+GVTT +LD LA
Sbjct: 1 MYVYKRDGRKEPVQFDKITARISRLCYGLDPKHIDAVKVTQRIISGVYEGVTTIELDNLA 60
Query: 61 AETAAGMTANHPDYASLAARIAVSNLHKNTLKSFSETVKVMYNHFNHRSGKKAPLIADDV 120
AET A MT HPDYA+LAARIA+SNLHK T K FS+ V+ +Y + N +GK AP+I+DDV
Sbjct: 61 AETCAYMTTVHPDYATLAARIAISNLHKQTTKQFSKVVEDLYRYVNAATGKPAPMISDDV 120
Query: 121 YEIIIKNAARLDSEIIYDRDFDYDYFGFKTLERSYLLKVQGVVVERPQHMIMRVSVGIHK 180
Y I+++N +L+S I+YDRDF Y YFGFKTLERSYLL++ G V ERPQH+IMRV++GIH
Sbjct: 121 YNIVMENKDKLNSAIVYDRDFQYSYFGFKTLERSYLLRINGQVAERPQHLIMRVALGIHG 180
Query: 181 DDVESAVKTYHFMSQRWFTHASPTLFNAGTPRPQLSSCFLVCMKEDSIEGIYDTLKECAV 240
D+E+A++TY+ MS ++FTHASPTLFNAGTP+PQ+SSCFLV MKEDSIEGIYDTLKECA+
Sbjct: 181 RDIEAALETYNLMSLKYFTHASPTLFNAGTPKPQMSSCFLVAMKEDSIEGIYDTLKECAL 240
Query: 241 ISKSAGGIGVSVHNIRAHGSYIRGTNGTSNGIVPMLRVFNDTARYVDQGGGKRKGAFAVY 300
ISK+AGGIG+ +HNIR+ GSYI GTNGTSNG++PM+RVFN+TARYVDQGG KR GAFA+Y
Sbjct: 241 ISKTAGGIGLHIHNIRSTGSYIAGTNGTSNGLIPMIRVFNNTARYVDQGGNKRPGAFALY 300
Query: 301 LEPWHADIFEFLELKINHGKEEQRARDLFYALWVPDLFMERVQSNGEWSLFCPNEAPGLA 360
LEPWHADIF+F++++ NHGKEE RARDLF ALW+PDLFM+RV+ NG W+LF P APGL+
Sbjct: 301 LEPWHADIFDFIDIRKNHGKEEIRARDLFPALWIPDLFMKRVEENGTWTLFSPTSAPGLS 360
Query: 361 DCWGEEYDKLYTQYEKAGKAKKIVQAQSLWFAILKSQIETGNPYMLFKDACNRKSNQQNL 420
DC+G+E++ LYT+YEK G+ K I +AQ LW++IL++Q ETG P++++KDACNRKSNQ+NL
Sbjct: 361 DCYGDEFEALYTRYEKEGRGKTI-KAQKLWYSILEAQTETGTPFVVYKDACNRKSNQKNL 419
Query: 421 GTIKSSNLCTEIIEYTSPTETAVCNLASIALPRYVRDKGLPVESHQSKLVGSRGSSSRYF 480
G IKSSNLC EI+EY++P ETAVCNLAS+ALP ++ G +S Y
Sbjct: 420 GVIKSSNLCCEIVEYSAPDETAVCNLASVALPAFIE-------------TSEDGKTSTY- 465
Query: 481 DFEKLGEVTAVVTTNLNKIIDVNYYPVETAERSNLRHRPIGIGVQGLADTFILLGMAFDS 540
+F+KL E+ VVT NLN++ID NYYPVE A +SN+RHRPI +GVQGLADTF+LL + FDS
Sbjct: 466 NFKKLHEIAKVVTRNLNRVIDRNYYPVEEARKSNMRHRPIALGVQGLADTFMLLRLPFDS 525
Query: 541 PEAQQLNKDIFETIYYHALKTSCELAAKEGPYETYSGSPVSKGILQPDMWGVTPSNLWDW 600
EA+ LN IFETIY+ +++ SCELA K+GPYET+ GSP S+GILQ DMW P +WDW
Sbjct: 526 EEARLLNIQIFETIYHASMEASCELAQKDGPYETFQGSPASQGILQFDMWDQKPYGMWDW 585
Query: 601 GALREMISKTGVRNSLLVAPMPTASTSQILGNNECFEPYTSNIYNRRVLSGEFVVVNKHL 660
LR+ I K GVRNSL +APMPTASTSQILG NECFEP TSN+Y+RRVLSGEF VVN +L
Sbjct: 586 DTLRKDIMKHGVRNSLTMAPMPTASTSQILGYNECFEPVTSNMYSRRVLSGEFQVVNPYL 645
Query: 661 LHDLTEMGLWNPALKNKIIYDNGSVQNLSEIPAELKVIYKTVWEIKQKILVDMAVDRGCY 720
L DL ++G+W+ +K +I NGS+Q L +P ELK +YKTVWEI QK +++MA DR Y
Sbjct: 646 LRDLVDLGIWDEGMKQYLITQNGSIQGLPNVPQELKDLYKTVWEISQKTIINMAADRSVY 705
Query: 721 IDQSQSLNIHMDKPNFGKLTSLHFYAWSKGLKTGMYYLRTRAASDAIKFTVDTSAIKDQP 780
IDQS SLN+ + P GKLTS+HFY W KGLKTGMYYLRT+AAS AI+FT+D I DQ
Sbjct: 706 IDQSHSLNLFLRAPTMGKLTSMHFYGWKKGLKTGMYYLRTQAASAAIQFTID-QKIADQA 764
Query: 781 KVKEAD 786
AD
Sbjct: 765 TENVAD 770
>RIR3_YEAST (P21672) Ribonucleoside-diphosphate reductase large
chain 2 (EC 1.17.4.1) (Ribonucleotide reductase)
(Ribonucleotide reductase DNA damage-inducible
regulatory subunit)
Length = 869
Score = 1035 bits (2676), Expect = 0.0
Identities = 489/772 (63%), Positives = 617/772 (79%), Gaps = 15/772 (1%)
Query: 1 MYVVKRDGRQEAVHFDKITARLKKLSYGLSTEHCDPVLVAQKVCAGVYKGVTTSQLDELA 60
MYV+KRDGR+E V FDKIT+R+ +LSYGL D V V Q++ +GVY GVTT +LD LA
Sbjct: 1 MYVIKRDGRKEPVQFDKITSRITRLSYGLDPNRIDAVKVTQRIISGVYSGVTTVELDNLA 60
Query: 61 AETAAGMTANHPDYASLAARIAVSNLHKNTLKSFSETVKVMYNHFNHRSGKKAPLIADDV 120
AET A MT HPDYA+LAARIA+SNLHK T K FS+ ++ +++ N +GK AP+I+D++
Sbjct: 61 AETCAYMTTVHPDYATLAARIAISNLHKQTTKQFSKVIEDLHDWINPATGKHAPMISDEI 120
Query: 121 YEIIIKNAARLDSEIIYDRDFDYDYFGFKTLERSYLLKVQGVVVERPQHMIMRVSVGIHK 180
Y I+++N L+S I+YDRDF Y YFGFKTLERSYLL++ G V ERPQH++MRV++GIH
Sbjct: 121 YNIVMENKDTLNSAIVYDRDFQYTYFGFKTLERSYLLRLNGEVAERPQHLVMRVALGIHG 180
Query: 181 DDVESAVKTYHFMSQRWFTHASPTLFNAGTPRPQLSSCFLVCMKEDSIEGIYDTLKECAV 240
D+ES +KTY+ MS R+FTHASPTLFNAGTP PQ+SSCFL+ MK+DSIEGIYDTLKECA+
Sbjct: 181 SDIESVLKTYNLMSLRYFTHASPTLFNAGTPHPQMSSCFLIAMKDDSIEGIYDTLKECAM 240
Query: 241 ISKSAGGIGVSVHNIRAHGSYIRGTNGTSNGIVPMLRVFNDTARYVDQGGGKRKGAFAVY 300
ISK+AGG+G+ ++NIR+ GSYI GTNGTSNG++PM+RVFN+TARYVDQGG KR GAFA++
Sbjct: 241 ISKTAGGVGLHINNIRSTGSYIAGTNGTSNGLIPMIRVFNNTARYVDQGGNKRPGAFALF 300
Query: 301 LEPWHADIFEFLELKINHGKEEQRARDLFYALWVPDLFMERVQSNGEWSLFCPNEAPGLA 360
LEPWHADIF+F++++ HGKEE RARDLF ALW+PDLFM+RVQ +G W+LF P+ APGL
Sbjct: 301 LEPWHADIFDFVDIRKTHGKEEIRARDLFPALWIPDLFMKRVQEDGPWTLFSPSAAPGLD 360
Query: 361 DCWGEEYDKLYTQYEKAGKAKKIVQAQSLWFAILKSQIETGNPYMLFKDACNRKSNQQNL 420
D WG+E+++LYT+YE+ G+ K I +AQ LW+AIL++Q ETG P+M++KDACNRK+NQQNL
Sbjct: 361 DVWGDEFEELYTRYEREGRGKTI-KAQKLWYAILQAQTETGTPFMVYKDACNRKTNQQNL 419
Query: 421 GTIKSSNLCTEIIEYTSPTETAVCNLASIALPRYVRDKGLPVESHQSKLVGSRGSSSRYF 480
GTIKSSNLC EI+EY+SP ETAVCNLASIALP +V V G ++ Y
Sbjct: 420 GTIKSSNLCCEIVEYSSPDETAVCNLASIALPAFVE-------------VSEDGKTASY- 465
Query: 481 DFEKLGEVTAVVTTNLNKIIDVNYYPVETAERSNLRHRPIGIGVQGLADTFILLGMAFDS 540
+FE+L E+ V+T NLN++ID NYYPV A SN++HRPI +GVQGLADT+++L + F+S
Sbjct: 466 NFERLHEIAKVITHNLNRVIDRNYYPVPEARNSNMKHRPIALGVQGLADTYMMLRLPFES 525
Query: 541 PEAQQLNKDIFETIYYHALKTSCELAAKEGPYETYSGSPVSKGILQPDMWGVTPSNLWDW 600
EAQ LNK IFETIY+ L+ SCELA KEG Y T+ GSP SKGILQ DMW P +WDW
Sbjct: 526 EEAQTLNKQIFETIYHATLEASCELAQKEGKYSTFEGSPASKGILQFDMWNAKPFGMWDW 585
Query: 601 GALREMISKTGVRNSLLVAPMPTASTSQILGNNECFEPYTSNIYNRRVLSGEFVVVNKHL 660
LR+ I K G+RNSL +APMPTASTSQILG NECFEP TSN+Y+RRVLSGEF VVN +L
Sbjct: 586 ETLRKDIVKHGLRNSLTMAPMPTASTSQILGYNECFEPVTSNMYSRRVLSGEFQVVNPYL 645
Query: 661 LHDLTEMGLWNPALKNKIIYDNGSVQNLSEIPAELKVIYKTVWEIKQKILVDMAVDRGCY 720
L DL ++G+W+ ++K +I NGS+Q L +P ELK +YKTVWEI QK +++MA DR Y
Sbjct: 646 LRDLVDLGIWDDSMKQYLITQNGSIQGLPNVPQELKELYKTVWEISQKTIINMAADRAIY 705
Query: 721 IDQSQSLNIHMDKPNFGKLTSLHFYAWSKGLKTGMYYLRTRAASDAIKFTVD 772
IDQS SLN+ + P+ GK+TS+HFY W KGLKTGMYYLRT+AAS AI+FT+D
Sbjct: 706 IDQSHSLNLFLQAPSMGKITSMHFYGWKKGLKTGMYYLRTQAASAAIQFTID 757
>RIR1_PLAF4 (P50648) Ribonucleoside-diphosphate reductase large
chain (EC 1.17.4.1) (Ribonucleotide reductase R1
subunit)
Length = 806
Score = 1024 bits (2648), Expect = 0.0
Identities = 507/824 (61%), Positives = 627/824 (75%), Gaps = 34/824 (4%)
Query: 1 MYVVKRDGRQEAVHFDKITARLKKLSYGLSTEHCDPVLVAQKVCAGVYKGVTTSQLDELA 60
MYV+ R G +E + FD+I R+++LSYGL E DP V Q V G+Y G+ T +LDELA
Sbjct: 1 MYVLNRKGEEEDISFDQILKRIQRLSYGLH-ELVDPARVTQGVINGMYSGIKTCELDELA 59
Query: 61 AETAAGMTANHPDYASLAARIAVSNLHKNTLKSFSETVKVMYNHFNHRSGKKAPLIADDV 120
A+T A M HPD++ LAARI NLHKNT +E + +Y + + R G+ A LI+ +V
Sbjct: 60 AQTCAYMATTHPDFSILAARITTDNLHKNTSDDVAEVAEALYTYKDVR-GRPASLISKEV 118
Query: 121 YEIIIKNAARLDSEIIYDRDFDYDYFGFKTLERSYLLKVQGVVVERPQHMIMRVSVGIHK 180
Y+ I+ + RL+ EI Y RDF+YDYFGFKTLERSYLL++ ++ERPQH++MRVS+GIH
Sbjct: 119 YDFILLHKDRLNKEIDYTRDFNYDYFGFKTLERSYLLRINNKIIERPQHLLMRVSIGIHI 178
Query: 181 DDVESAVKTYHFMSQRWFTHASPTLFNAGTPRPQLSSCFLVCMKEDSIEGIYDTLKECAV 240
DD++ A++TYH MSQ++FTHA+PTLFN+GTPRPQ+SSCFL+ MK DSIEGI++TLK+CA+
Sbjct: 179 DDIDKALETYHLMSQKYFTHATPTLFNSGTPRPQMSSCFLLSMKADSIEGIFETLKQCAL 238
Query: 241 ISKSAGGIGVSVHNIRAHGSYIRGTNGTSNGIVPMLRVFNDTARYVDQGGGKRKGAFAVY 300
ISK+AGGIGV+V +IR SYIRGTNG SNG+VPMLRVFNDTARYVDQGGGKRKG+FAVY
Sbjct: 239 ISKTAGGIGVAVQDIRGQNSYIRGTNGISNGLVPMLRVFNDTARYVDQGGGKRKGSFAVY 298
Query: 301 LEPWHADIFEFLELKINHGKEEQRARDLFYALWVPDLFMERVQSNGEWSLFCPNEAPGLA 360
+EPWH+DIFEFL+L+ NHGKEE RARDLFYA+WVPDLFM+RV+ N W+L CPNE PGL+
Sbjct: 299 IEPWHSDIFEFLDLRKNHGKEELRARDLFYAVWVPDLFMKRVKENKNWTLMCPNECPGLS 358
Query: 361 DCWGEEYDKLYTQYEKAGKAKKIVQAQSLWFAILKSQIETGNPYMLFKDACNRKSNQQNL 420
+ WGEE++KLYT+YE+ KK V AQ LWFAIL+SQIETG PYML+KD+CN KSNQ+NL
Sbjct: 359 ETWGEEFEKLYTKYEEENMGKKTVLAQDLWFAILQSQIETGVPYMLYKDSCNAKSNQKNL 418
Query: 421 GTIKSSNLCTEIIEYTSPTETAVCNLASIALPRYVRDKGLPVESHQSKLVGSRGSSSRYF 480
GTIK SNLC EIIEYTSP E AVCNLASIAL ++V + F
Sbjct: 419 GTIKCSNLCCEIIEYTSPDEVAVCNLASIALCKFV------------------DLEKKEF 460
Query: 481 DFEKLGEVTAVVTTNLNKIIDVNYYPVETAERSNLRHRPIGIGVQGLADTFILLGMAFDS 540
+F+KL E+T ++T NL+KII+ NYYPV+ A+ SN RHRPIGIGVQGLADTF+LL ++S
Sbjct: 461 NFKKLYEITKIITRNLDKIIERNYYPVKEAKTSNTRHRPIGIGVQGLADTFMLLRYPYES 520
Query: 541 PEAQQLNKDIFETIYYHALKTSCELAAKEGPYETYSGSPVSKGILQPDMWGVTPSN-LWD 599
A++LNK IFET+YY AL+ S ELA+ GPYE+Y GSP S+GILQ DMW N WD
Sbjct: 521 DAAKELNKRIFETMYYAALEMSVELASIHGPYESYQGSPASQGILQFDMWNAKVDNKYWD 580
Query: 600 WGALREMISKTGVRNSLLVAPMPTASTSQILGNNECFEPYTSNIYNRRVLSGEFVVVNKH 659
W L+ I K G+RNSLL+APMPTASTSQILGNNE FEPYTSNIY RRVLSGEF VVN H
Sbjct: 581 WDELKAKIRKHGLRNSLLLAPMPTASTSQILGNNESFEPYTSNIYYRRVLSGEFFVVNPH 640
Query: 660 LLHDLTEMGLWNPALKNKIIYDNGSVQNLSEIPAELKVIYKTVWEIKQKILVDMAVDRGC 719
LL DL + GLW+ +K ++I NGS+Q +SEIP +LK +YKTVWEIKQK ++DMA DRG
Sbjct: 641 LLKDLFDRGLWDEDMKQQLIAHNGSIQYISEIPDDLKELYKTVWEIKQKNIIDMAADRGI 700
Query: 720 YIDQSQSLNIHMDKPNFGKLTSLHFYAWSKGLKTGMYYLRTRAASDAIKFTVDTSAIKDQ 779
+IDQSQSLNI++ KP F KL+S+HFY W KGLKTG YYLRT+AA+DAIKFTVDT K+
Sbjct: 701 FIDQSQSLNIYIQKPTFAKLSSMHFYGWEKGLKTGAYYLRTQAATDAIKFTVDTHVAKNA 760
Query: 780 PKVKEADDE-----------DDDTKMAQMVCSL--TNRDECEAC 810
K+K AD ++ + Q VC L N ++C C
Sbjct: 761 VKLKNADGVQITREVSRETISTESTVTQNVCPLRRNNDEQCLMC 804
>RIR1_VARV (P32984) Ribonucleoside-diphosphate reductase large chain
(EC 1.17.4.1) (Ribonucleotide reductase)
Length = 771
Score = 1009 bits (2610), Expect = 0.0
Identities = 488/777 (62%), Positives = 602/777 (76%), Gaps = 21/777 (2%)
Query: 1 MYVVKRDGRQEAVHFDKITARLKKLSYGLSTEHCDPVLVAQKVCAGVYKGVTTSQLDELA 60
M+V+KR+G +E V FDKIT+R++KL YGL+T+H DP+ +A KV G+Y GVTT +LD L
Sbjct: 1 MFVIKRNGYKENVMFDKITSRIRKLCYGLNTDHIDPIKIAMKVIQGIYNGVTTVELDTLT 60
Query: 61 AETAAGMTANHPDYASLAARIAVSNLHKNTLKSFSETVKVMYNHFNHRSGKKAPLIADDV 120
AE AA T HPDYA LAARIAVSNLHK T K FSE +K ++N+ N ++GK +P+I+
Sbjct: 61 AEIAATCTTQHPDYAILAARIAVSNLHKETKKLFSEVMKDLFNYVNPKNGKHSPIISSIT 120
Query: 121 YEIIIKNAARLDSEIIYDRDFDYDYFGFKTLERSYLLKVQGVVVERPQHMIMRVSVGIHK 180
+++ K +L+S IIY+RDF Y+YFGFKTLE+SYLLK+ +VERPQHM+MRV+VGIH+
Sbjct: 121 MDVVNKYKDKLNSVIIYERDFSYNYFGFKTLEKSYLLKINNKIVERPQHMLMRVAVGIHQ 180
Query: 181 DDVESAVKTYHFMSQRWFTHASPTLFNAGTPRPQLSSCFLVCMKEDSIEGIYDTLKECAV 240
D++SA++TY+ +S++WFTHASPTLFNAGT R Q+SSCFL+ M +DSIEGIYDTLK CA+
Sbjct: 181 WDIDSAIETYNLLSEKWFTHASPTLFNAGTSRHQMSSCFLLNMMDDSIEGIYDTLKRCAL 240
Query: 241 ISKSAGGIGVSVHNIRAHGSYIRGTNGTSNGIVPMLRVFNDTARYVDQGGGKRKGAFAVY 300
ISK AGGIG+S+ NIRA GSYI GTNG SNGI+PMLRV+N+TARY+DQGG KR G +Y
Sbjct: 241 ISKMAGGIGLSISNIRASGSYISGTNGASNGIIPMLRVYNNTARYIDQGGNKRPGVMTIY 300
Query: 301 LEPWHADIFEFLELKINHGKEEQRARDLFYALWVPDLFMERVQSNGEWSLFCPNEAPGLA 360
LEPWH+DI FL+LK N G EE R RDLF ALW+PDLFM+RV+ +GEWSL CP+E PGL
Sbjct: 301 LEPWHSDIMAFLDLKKNTGNEEHRTRDLFIALWIPDLFMKRVKDDGEWSLMCPDECPGLD 360
Query: 361 DCWGEEYDKLYTQYEKAGKAKKIVQAQSLWFAILKSQIETGNPYMLFKDACNRKSNQQNL 420
+ WG+E+++LYT YE+ + K I++A+ +W AI++SQIETG P++L+KDACN+KSNQQNL
Sbjct: 361 NVWGDEFERLYTLYEREKRYKSIIKARVVWKAIIESQIETGTPFILYKDACNKKSNQQNL 420
Query: 421 GTIKSSNLCTEIIEYTSPTETAVCNLASIALPRYVRDKGLPVESHQSKLVGSRGSSSRYF 480
GTIK SNLCTEII+Y E AVCNLASIAL +V D F
Sbjct: 421 GTIKCSNLCTEIIQYADANEVAVCNLASIALNMFVID--------------------GQF 460
Query: 481 DFEKLGEVTAVVTTNLNKIIDVNYYPVETAERSNLRHRPIGIGVQGLADTFILLGMAFDS 540
DF KL +V V+ NLNKIID+NYYP+ AE SN RHRPIGIGVQGLAD FILL FDS
Sbjct: 461 DFLKLKDVVKVIVRNLNKIIDINYYPIPEAEISNKRHRPIGIGVQGLADAFILLNYPFDS 520
Query: 541 PEAQQLNKDIFETIYYHALKTSCELAAKEGPYETYSGSPVSKGILQPDMWGVTPSNLWDW 600
EAQ LNK IFETIYY AL+ SCELA KEGPY+TY GS S GILQ D+W V PS+LW+W
Sbjct: 521 LEAQDLNKKIFETIYYGALEASCELAEKEGPYDTYVGSYASNGILQYDLWNVVPSDLWNW 580
Query: 601 GALREMISKTGVRNSLLVAPMPTASTSQILGNNECFEPYTSNIYNRRVLSGEFVVVNKHL 660
L++ I G+RNSLLVAPMPTAST+QILGNNE EPYTSNIY RRVLSGEF VVN HL
Sbjct: 581 EPLKDKIRTYGLRNSLLVAPMPTASTAQILGNNESVEPYTSNIYTRRVLSGEFQVVNPHL 640
Query: 661 LHDLTEMGLWNPALKNKIIYDNGSVQNLSEIPAELKVIYKTVWEIKQKILVDMAVDRGCY 720
L LTE LWN +KN+I+ D GS+QN + +P ++K +YKT+WEI QK ++ MA DRG +
Sbjct: 641 LRVLTERKLWNDEIKNRIMVDGGSIQN-TNLPEDIKRVYKTIWEIPQKTIIKMAADRGAF 699
Query: 721 IDQSQSLNIHMDKPNFGKLTSLHFYAWSKGLKTGMYYLRTRAASDAIKFTVDTSAIK 777
IDQSQS+NIH+ P++ KLTS+HFY WS GLKTGMYYLRT+ AS I+FT+D IK
Sbjct: 700 IDQSQSMNIHIADPSYSKLTSMHFYGWSLGLKTGMYYLRTKPASAPIQFTLDKDKIK 756
>RIR1_VACCV (P12848) Ribonucleoside-diphosphate reductase large
chain (EC 1.17.4.1) (Ribonucleotide reductase)
Length = 771
Score = 1009 bits (2609), Expect = 0.0
Identities = 489/777 (62%), Positives = 604/777 (76%), Gaps = 21/777 (2%)
Query: 1 MYVVKRDGRQEAVHFDKITARLKKLSYGLSTEHCDPVLVAQKVCAGVYKGVTTSQLDELA 60
M+V+KR+G +E V FDKIT+R++KL YGL+T+H DP+ +A KV G+Y GVTT +LD LA
Sbjct: 1 MFVIKRNGYKENVMFDKITSRIRKLCYGLNTDHIDPIKIAMKVIQGIYNGVTTVELDTLA 60
Query: 61 AETAAGMTANHPDYASLAARIAVSNLHKNTLKSFSETVKVMYNHFNHRSGKKAPLIADDV 120
AE AA T HPDYA LAARIAVSNLHK T K FSE ++ ++N+ N ++GK +P+I+
Sbjct: 61 AEIAATCTTQHPDYAILAARIAVSNLHKETKKLFSEVMEDLFNYVNPKNGKHSPIISSIT 120
Query: 121 YEIIIKNAARLDSEIIYDRDFDYDYFGFKTLERSYLLKVQGVVVERPQHMIMRVSVGIHK 180
+I+ K +L+S IIY+RDF Y+YFGFKTLE+SYLLK+ +VERPQHM+MRV+VGIH+
Sbjct: 121 MDIVNKYKDKLNSVIIYERDFSYNYFGFKTLEKSYLLKINNKIVERPQHMLMRVAVGIHQ 180
Query: 181 DDVESAVKTYHFMSQRWFTHASPTLFNAGTPRPQLSSCFLVCMKEDSIEGIYDTLKECAV 240
D++SA++TY+ +S++WFTHASPTLFNAGT R Q+SSCFL+ M +DSIEGIYDTLK CA+
Sbjct: 181 WDIDSAIETYNLLSEKWFTHASPTLFNAGTSRHQMSSCFLLNMIDDSIEGIYDTLKRCAL 240
Query: 241 ISKSAGGIGVSVHNIRAHGSYIRGTNGTSNGIVPMLRVFNDTARYVDQGGGKRKGAFAVY 300
ISK AGGIG+S+ NIRA GSYI GTNG SNGI+PMLRV+N+TARY+DQGG KR G A+Y
Sbjct: 241 ISKMAGGIGLSISNIRASGSYISGTNGISNGIIPMLRVYNNTARYIDQGGNKRPGVMAIY 300
Query: 301 LEPWHADIFEFLELKINHGKEEQRARDLFYALWVPDLFMERVQSNGEWSLFCPNEAPGLA 360
LEPWH+DI FL+LK N G EE R RDLF ALW+PDLFM+RV+ +GEWSL CP+E PGL
Sbjct: 301 LEPWHSDIMAFLDLKKNTGNEEHRTRDLFIALWIPDLFMKRVKDDGEWSLMCPDECPGLD 360
Query: 361 DCWGEEYDKLYTQYEKAGKAKKIVQAQSLWFAILKSQIETGNPYMLFKDACNRKSNQQNL 420
+ WG+E+++LYT YE+ + K I++A+ +W AI++SQIETG P++L+KDACN+KSNQQNL
Sbjct: 361 NVWGDEFERLYTLYERERRYKSIIKARVVWKAIIESQIETGTPFILYKDACNKKSNQQNL 420
Query: 421 GTIKSSNLCTEIIEYTSPTETAVCNLASIALPRYVRDKGLPVESHQSKLVGSRGSSSRYF 480
GTIK SNLCTEII+Y E AVCNLAS+AL +V D F
Sbjct: 421 GTIKCSNLCTEIIQYADANEVAVCNLASVALNMFVID--------------------GRF 460
Query: 481 DFEKLGEVTAVVTTNLNKIIDVNYYPVETAERSNLRHRPIGIGVQGLADTFILLGMAFDS 540
DF KL +V V+ NLNKIID+NYYP+ AE SN RHRPIGIGVQGLAD FILL FDS
Sbjct: 461 DFLKLKDVVKVIVRNLNKIIDINYYPIPEAEISNKRHRPIGIGVQGLADAFILLNYPFDS 520
Query: 541 PEAQQLNKDIFETIYYHALKTSCELAAKEGPYETYSGSPVSKGILQPDMWGVTPSNLWDW 600
EAQ LNK IFETIYY AL+ SCELA KEGPY+TY GS S GILQ D+W V PS+LW+W
Sbjct: 521 LEAQDLNKKIFETIYYGALEASCELAEKEGPYDTYVGSYASNGILQYDLWNVVPSDLWNW 580
Query: 601 GALREMISKTGVRNSLLVAPMPTASTSQILGNNECFEPYTSNIYNRRVLSGEFVVVNKHL 660
L++ I G+RNSLLVAPMPTAST+QILGNNE EPYTSNIY RRVLSGEF VVN HL
Sbjct: 581 EPLKDKIRTYGLRNSLLVAPMPTASTAQILGNNESVEPYTSNIYTRRVLSGEFQVVNPHL 640
Query: 661 LHDLTEMGLWNPALKNKIIYDNGSVQNLSEIPAELKVIYKTVWEIKQKILVDMAVDRGCY 720
L LTE LWN +KN+I+ D GS+QN + +P ++K +YKT+WEI QK ++ MA DRG +
Sbjct: 641 LRVLTERKLWNDEIKNRIMADGGSIQN-TNLPEDIKRVYKTIWEIPQKTIIKMAADRGAF 699
Query: 721 IDQSQSLNIHMDKPNFGKLTSLHFYAWSKGLKTGMYYLRTRAASDAIKFTVDTSAIK 777
IDQSQS+NIH+ P++ KLTS+HFY WS GLKTGMYYLRT+ AS I+FT+D IK
Sbjct: 700 IDQSQSMNIHIADPSYSKLTSMHFYGWSLGLKTGMYYLRTKPASAPIQFTLDKDKIK 756
>RIR1_VACCC (P20503) Ribonucleoside-diphosphate reductase large
chain (EC 1.17.4.1) (Ribonucleotide reductase)
Length = 771
Score = 1009 bits (2609), Expect = 0.0
Identities = 489/777 (62%), Positives = 604/777 (76%), Gaps = 21/777 (2%)
Query: 1 MYVVKRDGRQEAVHFDKITARLKKLSYGLSTEHCDPVLVAQKVCAGVYKGVTTSQLDELA 60
M+V+KR+G +E V FDKIT+R++KL YGL+T+H DP+ +A KV G+Y GVTT +LD LA
Sbjct: 1 MFVIKRNGYKENVMFDKITSRIRKLCYGLNTDHIDPIKIAMKVIQGIYNGVTTVELDTLA 60
Query: 61 AETAAGMTANHPDYASLAARIAVSNLHKNTLKSFSETVKVMYNHFNHRSGKKAPLIADDV 120
AE AA T HPDYA LAARIAVSNLHK T K FSE ++ ++N+ N ++GK +P+I+
Sbjct: 61 AEIAATCTTQHPDYAILAARIAVSNLHKETKKLFSEVMEDLFNYVNPKNGKHSPIISSIT 120
Query: 121 YEIIIKNAARLDSEIIYDRDFDYDYFGFKTLERSYLLKVQGVVVERPQHMIMRVSVGIHK 180
+I+ K +L+S IIY+RDF Y+YFGFKTLE+SYLLK+ +VERPQHM+MRV+VGIH+
Sbjct: 121 MDIVNKYKDKLNSVIIYERDFSYNYFGFKTLEKSYLLKINNKIVERPQHMLMRVAVGIHQ 180
Query: 181 DDVESAVKTYHFMSQRWFTHASPTLFNAGTPRPQLSSCFLVCMKEDSIEGIYDTLKECAV 240
D++SA++TY+ +S++WFTHASPTLFNAGT R Q+SSCFL+ M +DSIEGIYDTLK CA+
Sbjct: 181 WDIDSAIETYNLLSEKWFTHASPTLFNAGTSRHQMSSCFLLNMIDDSIEGIYDTLKRCAL 240
Query: 241 ISKSAGGIGVSVHNIRAHGSYIRGTNGTSNGIVPMLRVFNDTARYVDQGGGKRKGAFAVY 300
ISK AGGIG+S+ NIRA GSYI GTNG SNGI+PMLRV+N+TARY+DQGG KR G A+Y
Sbjct: 241 ISKMAGGIGLSISNIRASGSYISGTNGISNGIIPMLRVYNNTARYIDQGGNKRPGVMAIY 300
Query: 301 LEPWHADIFEFLELKINHGKEEQRARDLFYALWVPDLFMERVQSNGEWSLFCPNEAPGLA 360
LEPWH+DI FL+LK N G EE R RDLF ALW+PDLFM+RV+ +GEWSL CP+E PGL
Sbjct: 301 LEPWHSDIMAFLDLKKNTGNEEHRTRDLFIALWIPDLFMKRVKDDGEWSLMCPDECPGLD 360
Query: 361 DCWGEEYDKLYTQYEKAGKAKKIVQAQSLWFAILKSQIETGNPYMLFKDACNRKSNQQNL 420
+ WG+E+++LYT YE+ + K I++A+ +W AI++SQIETG P++L+KDACN+KSNQQNL
Sbjct: 361 NVWGDEFERLYTLYERERRYKSIIKARVVWKAIIESQIETGTPFILYKDACNKKSNQQNL 420
Query: 421 GTIKSSNLCTEIIEYTSPTETAVCNLASIALPRYVRDKGLPVESHQSKLVGSRGSSSRYF 480
GTIK SNLCTEII+Y E AVCNLAS+AL +V D F
Sbjct: 421 GTIKCSNLCTEIIQYADANEVAVCNLASVALNMFVID--------------------GRF 460
Query: 481 DFEKLGEVTAVVTTNLNKIIDVNYYPVETAERSNLRHRPIGIGVQGLADTFILLGMAFDS 540
DF KL +V V+ NLNKIID+NYYP+ AE SN RHRPIGIGVQGLAD FILL FDS
Sbjct: 461 DFLKLKDVVKVIVRNLNKIIDINYYPIPEAEISNKRHRPIGIGVQGLADAFILLNYPFDS 520
Query: 541 PEAQQLNKDIFETIYYHALKTSCELAAKEGPYETYSGSPVSKGILQPDMWGVTPSNLWDW 600
EAQ LNK IFETIYY AL+ SCELA KEGPY+TY GS S GILQ D+W V PS+LW+W
Sbjct: 521 LEAQDLNKKIFETIYYGALEASCELAEKEGPYDTYVGSYASNGILQYDLWNVVPSDLWNW 580
Query: 601 GALREMISKTGVRNSLLVAPMPTASTSQILGNNECFEPYTSNIYNRRVLSGEFVVVNKHL 660
L++ I G+RNSLLVAPMPTAST+QILGNNE EPYTSNIY RRVLSGEF VVN HL
Sbjct: 581 EPLKDKIRTYGLRNSLLVAPMPTASTAQILGNNESVEPYTSNIYTRRVLSGEFQVVNPHL 640
Query: 661 LHDLTEMGLWNPALKNKIIYDNGSVQNLSEIPAELKVIYKTVWEIKQKILVDMAVDRGCY 720
L LTE LWN +KN+I+ D GS+QN + +P ++K +YKT+WEI QK ++ MA DRG +
Sbjct: 641 LRVLTERKLWNDEIKNRIMADGGSIQN-TNLPEDIKRVYKTIWEIPQKTIIKMAADRGAF 699
Query: 721 IDQSQSLNIHMDKPNFGKLTSLHFYAWSKGLKTGMYYLRTRAASDAIKFTVDTSAIK 777
IDQSQS+NIH+ P++ KLTS+HFY WS GLKTGMYYLRT+ AS I+FT+D IK
Sbjct: 700 IDQSQSMNIHIADPSYSKLTSMHFYGWSLGLKTGMYYLRTKPASAPIQFTLDKDKIK 756
>RIR1_CRYPV (O61065) Ribonucleoside-diphosphate reductase large
chain (EC 1.17.4.1) (Ribonucleotide reductase R1
subunit)
Length = 803
Score = 1004 bits (2596), Expect = 0.0
Identities = 493/818 (60%), Positives = 621/818 (75%), Gaps = 28/818 (3%)
Query: 1 MYVVKRDGRQEAVHFDKITARLKKLSYGLSTEHCDPVLVAQKVCAGVYKGVTTSQLDELA 60
MYVV R G +E V FD+I +R+ KLSYGL DP V Q V G+Y G+ TS+LDELA
Sbjct: 1 MYVVNRKGEEEPVSFDQILSRITKLSYGLHPL-VDPARVTQAVINGLYSGIKTSELDELA 59
Query: 61 AETAAGMTANHPDYASLAARIAVSNLHKNTLKSFSETVKVMYNHFNHRSGKKAPLIADDV 120
++T A M A H D++ LAARI+ SNLHKNT + +YN F G APLI+ V
Sbjct: 60 SQTCAYMAATHNDFSKLAARISTSNLHKNTSSDIGDVASQLYN-FKDNQGCPAPLISKPV 118
Query: 121 YEIIIKNAARLDSEIIYDRDFDYDYFGFKTLERSYLLKVQGVVVERPQHMIMRVSVGIHK 180
Y+ I++N R++S+I + +DF+YDYF FKTLERSYLLK+ VVERPQH++MRVS GIH
Sbjct: 119 YDFIMENRERINSKIDFSKDFEYDYFAFKTLERSYLLKIDNKVVERPQHLLMRVSCGIHC 178
Query: 181 DDVESAVKTYHFMSQRWFTHASPTLFNAGTPRPQLSSCFLVCMKEDSIEGIYDTLKECAV 240
D+E+A++TY +SQ++FTHA+PTLFN+GTPRPQ+SSCFL+ + EDSI GI+DTL +CA
Sbjct: 179 GDIEAALETYELLSQKYFTHATPTLFNSGTPRPQMSSCFLLRIPEDSINGIFDTLTKCAN 238
Query: 241 ISKSAGGIGVSVHNIRAHGSYIRGTNGTSNGIVPMLRVFNDTARYVDQGGGKRKGAFAVY 300
ISK+AGG+GV+V NIR GSYIRGTNG SNG++PMLRV+NDTARY+DQGGGKRKGA A+Y
Sbjct: 239 ISKTAGGLGVAVSNIRGTGSYIRGTNGRSNGLIPMLRVYNDTARYIDQGGGKRKGAIAIY 298
Query: 301 LEPWHADIFEFLELKINHGKEEQRARDLFYALWVPDLFMERVQSNGEWSLFCPNEAPGLA 360
LEPWH D+ EF+E++ NHGKEE R RDLF ALWVPDLFMERV+ + +W+L CP+E GL
Sbjct: 299 LEPWHVDVVEFIEIRKNHGKEEMRCRDLFPALWVPDLFMERVEKDQDWTLMCPDECRGLQ 358
Query: 361 DCWGEEYDKLYTQYEKAGKAKKIVQAQSLWFAILKSQIETGNPYMLFKDACNRKSNQQNL 420
D WG+++ KLY +YEK G+ +K ++AQ LWF IL++QIETG P++ +KDA N KSNQ+NL
Sbjct: 359 DVWGDDFKKLYEEYEKQGRGRKTMKAQKLWFLILQAQIETGTPFICYKDAANSKSNQKNL 418
Query: 421 GTIKSSNLCTEIIEYTSPTETAVCNLASIALPRYVRDKGLPVESHQSKLVGSRGSSSRYF 480
GTI SSNLCTEIIEYTS E AVCNLASI LP++V DK +++ F
Sbjct: 419 GTIVSSNLCTEIIEYTSTDEVAVCNLASIGLPKFV-DK-----------------NNKTF 460
Query: 481 DFEKLGEVTAVVTTNLNKIIDVNYYPVETAERSNLRHRPIGIGVQGLADTFILLGMAFDS 540
DF+KL EVT V+T NLNK+IDV YY ++ ++SNLRHRP+GIG+QGLAD F++L M ++S
Sbjct: 461 DFDKLKEVTKVITRNLNKLIDVGYYSLKECKKSNLRHRPLGIGIQGLADCFMMLRMPYES 520
Query: 541 PEAQQLNKDIFETIYYHALKTSCELAAKEGPYETYSGSPVSKGILQPDMWGVTP-SNLWD 599
A++LNK IFE IYY AL SCELA K GPYETYSGSP SKGILQ DMWGVTP S L D
Sbjct: 521 EGAKKLNKQIFEVIYYAALDASCELAEKYGPYETYSGSPASKGILQFDMWGVTPDSGLCD 580
Query: 600 WGALREMISKTGVRNSLLVAPMPTASTSQILGNNECFEPYTSNIYNRRVLSGEFVVVNKH 659
W L++ ISK G+RNSLL++PMPTASTSQILGNNE FEP+TSNIY+RRVLSGEF VVN H
Sbjct: 581 WDLLKDRISKHGIRNSLLISPMPTASTSQILGNNESFEPFTSNIYHRRVLSGEFFVVNPH 640
Query: 660 LLHDLTEMGLWNPALKNKIIYDNGSVQNLSEIPAELKVIYKTVWEIKQKILVDMAVDRGC 719
LL+DL E+GLW+ LK II +NGS+QN+ IP +++ +YKTVWEIKQK ++DMA DRG
Sbjct: 641 LLNDLLELGLWDDRLKQNIIANNGSIQNILTIPEDIRELYKTVWEIKQKTVIDMAADRGP 700
Query: 720 YIDQSQSLNIHMDKPNFGKLTSLHFYAWSKGLKTGMYYLRTRAASDAIKFTVDTSAIKDQ 779
Y+ QSQSLNIHM+ NF KL+S+HFY W KGLKTG+YYLRT++A+ I+FTVD +K +
Sbjct: 701 YVCQSQSLNIHMENANFAKLSSMHFYGWKKGLKTGIYYLRTQSATRPIQFTVDQQLLKSE 760
Query: 780 PKVKEADD-------EDDDTKMAQMVCSLTNRDECEAC 810
K K++ + E + K+ TN + E C
Sbjct: 761 TKEKDSLETNKRQALEPEAQKLIACPLRPTNMKDDEEC 798
>RIR1_PLAFG (P50647) Ribonucleoside-diphosphate reductase large
chain (EC 1.17.4.1) (Ribonucleotide reductase R1
subunit)
Length = 804
Score = 984 bits (2545), Expect = 0.0
Identities = 487/805 (60%), Positives = 610/805 (75%), Gaps = 22/805 (2%)
Query: 1 MYVVKRDGRQEAVHFDKITARLKKLSYGLSTEHCDPVLVAQKVCAGVYKGVTTSQLDELA 60
MYV+ R G +E + FD+I R+++LSYGL P V Q V G+Y + T +LDELA
Sbjct: 1 MYVLNRKGEEEDISFDQILKRIQRLSYGLHKLGEYPACVTQGVINGMYSSIKTCELDELA 60
Query: 61 AETAAGMTANHPDYASLAARIAVSNLHKNTLKSFSETVKVMYNHFNHRSGKKAPLIADDV 120
A+T A M HPD++ LAARI NLHKNT +E + +Y + + R G+ A LI+ +V
Sbjct: 61 AQTCAYMATTHPDFSILAARITTDNLHKNTSDDVAEVAEALYTYKDGR-GRPASLISKEV 119
Query: 121 YEIIIKNAARLDSEIIYDRDFDYDYFGFKTLERSYLLKVQGVVVERPQHMIMRVSVGIHK 180
Y+ I+ + RL+ EI Y F+YDYFGFKTLERSYLL++ ++ERPQH++MRVS+GIH
Sbjct: 120 YDFILLHKVRLNKEIDYTTHFNYDYFGFKTLERSYLLRINNKIIERPQHLLMRVSIGIHI 179
Query: 181 DDVESAVKTYHFMSQRWFTHASPTLFNAGTPRPQLSSCFLVCMKEDSIEGIYDTLKECAV 240
DD++ A++TYH MSQ++FTHA+PTLFN+GTPRPQ+SSCFL+ MK DSIEGI++TLK+CA+
Sbjct: 180 DDIDKALETYHLMSQKYFTHATPTLFNSGTPRPQMSSCFLLSMKADSIEGIFETLKQCAL 239
Query: 241 ISKSAGGIGVSVHNIRAHGSYIRGTNGTSNGIVPMLRVFNDTARYVDQGGGKRKGAFAVY 300
ISK+AGGIGV+V +IR SYIRGTNG SNG+VPMLRVFNDTARYVDQGGGKRKG++AVY
Sbjct: 240 ISKTAGGIGVAVQDIRGQNSYIRGTNGISNGLVPMLRVFNDTARYVDQGGGKRKGSYAVY 299
Query: 301 LEPWHADIFEFLELKINHGKEEQRARDLFYALWVPDLFMERVQSNGEWSLFCPNEAPGLA 360
+EPWH+DIFEFL+L+ NHGKEE RARDLFYA+WVPDLFM+RV+ N W+L CPNE PGL+
Sbjct: 300 IEPWHSDIFEFLDLRKNHGKEELRARDLFYAVWVPDLFMKRVKENKNWTLMCPNECPGLS 359
Query: 361 DCWGEEYDKLYTQYEKAGKAKKIVQAQSLWFAILKSQIETGNPYMLFKDACNRKSNQQNL 420
+ WGEE++KLYT+YE+ KK V AQ LWFAIL+SQIETG P L+KD+CN K +NL
Sbjct: 360 ETWGEEFEKLYTKYEEENMGKKTVLAQDLWFAILQSQIETGVPIYLYKDSCNAKP-IKNL 418
Query: 421 GTIKSSNLCTEIIEYTSPTETAVCNLASIALPRYVRDKGLPVESHQSKLVGSRGSSSRYF 480
GTIK SNLC EIIEYTSP E AVCNLASIAL ++V + F
Sbjct: 419 GTIKCSNLCCEIIEYTSPDEVAVCNLASIALCKFV------------------DLEKKEF 460
Query: 481 DFEKLGEVTAVVTTNLNKIIDVNYYPVETAERSNLRHRPIGIGVQGLADTFILLGMAFDS 540
+F+KL E+T ++T NL+KII+ NYYPV+ A+ SN RHRPIGIGVQGLADTF+LL ++S
Sbjct: 461 NFKKLYEITKIITRNLDKIIERNYYPVKEAKTSNTRHRPIGIGVQGLADTFMLLRYLYES 520
Query: 541 PEAQQLNKDIFETIYYHALKTSCELAAKEGPYETYSGSPVSKGILQPDMWGVTPSN-LWD 599
A++LNK I+ET+YY AL+ S + + GPYE+Y GSP S+GILQ DMW N WD
Sbjct: 521 DAAKELNKRIYETMYYAALEMSVDW-LQSGPYESYQGSPGSQGILQFDMWNAKVDNKYWD 579
Query: 600 WGALREMISKTGVRNSLLVAPMPTASTSQILGNNECFEPYTSNIYNRRVLSGEFVVVNKH 659
W L+ I+KTG+RN LL+APMPTASTSQILGNNE FEPYTSNIY RRVLSGEF VVN H
Sbjct: 580 WDELKLKIAKTGLRNLLLLAPMPTASTSQILGNNESFEPYTSNIYYRRVLSGEFFVVNPH 639
Query: 660 LLHDLTEMGLWNPALKNKIIYDNGSVQNLSEIPAELKVIYKTVWEIKQKILVDMAVDRGC 719
LL DL + GLW+ +K ++I NGS+Q +SEIP +LK +YKTVWEIKQK ++DMA DRG
Sbjct: 640 LLKDLFDRGLWDEDMKQQLIAHNGSIQYISEIPDDLKELYKTVWEIKQKNIIDMAADRGY 699
Query: 720 YIDQSQSLNIHMDKPNFGKLTSLHFYAWSKGLKTGMYYLRTRAASDAIKFTVDTSAIKDQ 779
+IDQSQSLNI++ KP F KL+S+HFY W KGLKTG YYLRT+AA+DAIKFTVDT K+
Sbjct: 700 FIDQSQSLNIYIQKPTFAKLSSMHFYGWEKGLKTGAYYLRTQAATDAIKFTVDTHVAKNA 759
Query: 780 PKVKEADDEDDDTKMAQMVCSLTNR 804
K+K AD ++++ L R
Sbjct: 760 VKLKNADGVQITREVSRETIQLNQR 784
>RIR1_TRYBB (O15909) Ribonucleoside-diphosphate reductase large
chain (EC 1.17.4.1) (Ribonucleotide reductase R1
subunit)
Length = 838
Score = 952 bits (2461), Expect = 0.0
Identities = 477/805 (59%), Positives = 602/805 (74%), Gaps = 38/805 (4%)
Query: 3 VVKRDGRQEAVHFDKITARLKKLSYGLSTEHCDPVLVAQKVCAGVYKGVTTSQLDELAAE 62
V KRDG E + +R+ L G+ + + D + + V GV +G++TS LDEL AE
Sbjct: 8 VTKRDGSVEPYDEKVVRSRIVNLMSGIDSYYVDVDDLVRVVGEGVREGMSTSMLDELLAE 67
Query: 63 TAAGMTANHPDYASLAARIAVSNLHKNTLKSFSETVKVMYNHFNHRSGKKAPLIADDVYE 122
TAA HPDY LA R+AV+ LHK T +S ++ +V++ H + + + APLI++++++
Sbjct: 68 TAAYCVTKHPDYGLLAGRLAVTALHKTTTESVLDSFRVLHEHVSQATKRHAPLISEELWD 127
Query: 123 IIIKNAARLDSEIIYDRDFDYDYFGFKTLERSYLLKV---QGV--VVERPQHMIMRVSVG 177
I K++A L I Y+RDFD++YFG+KTLERSYLL+V +GV VVERPQ M +RV++G
Sbjct: 128 IANKHSAALQQIINYERDFDFEYFGYKTLERSYLLRVHKGRGVMEVVERPQQMFLRVALG 187
Query: 178 IHKDDVESAVKTYHFMSQRWFTHASPTLFNAGTPRPQLSSCFLVCMKEDSIEGIYDTLKE 237
IH +D+E +TY +MSQ +FTHA+PTLFNAGTP PQ+SSCFLV M+EDSI+GIYDTLK+
Sbjct: 188 IHGEDLERVKETYDYMSQGFFTHATPTLFNAGTPFPQMSSCFLVAMREDSIDGIYDTLKQ 247
Query: 238 CAVISKSAGGIGVSVHNIRAHGSYIRGTNGTSNGIVPMLRVFNDTARYVDQGGGKRKGAF 297
CA+ISKSAGGIG+ +HNIRA GSYI GTNGTSNG+VPMLRV+N+TARYVDQGGGKRKGAF
Sbjct: 248 CAIISKSAGGIGIHMHNIRAAGSYIAGTNGTSNGLVPMLRVWNNTARYVDQGGGKRKGAF 307
Query: 298 AVYLEPWHADIFEFLELKINHGKEEQRARDLFYALWVPDLFMERVQSNGEWSLFCPNEAP 357
A+YLEPWHADIF FL LK N GKE+QRARDLFY LW+PDLFMERV+S+G W+L PN AP
Sbjct: 308 AIYLEPWHADIFGFLLLKKNTGKEDQRARDLFYGLWIPDLFMERVESHGTWTLMDPNTAP 367
Query: 358 GLADCWGEEYDKLYTQYEKAGKAKKIVQAQSLWFAILKSQIETGNPYMLFKDACNRKSNQ 417
L+DC+G+E+ LY +YE+ G+ + +QAQ LWF IL+SQ+ETG P+ML+KDACN KSNQ
Sbjct: 368 FLSDCYGQEFTDLYERYEREGRGVRTIQAQELWFLILESQVETGVPFMLYKDACNFKSNQ 427
Query: 418 QNLGTIKSSNLCTEIIEYTSPTETAVCNLASIALPRYVRDKGLPVESHQSKLVGSRGSSS 477
+NLGTIK SNLCTEI+EYTS E AVCNLASIALPR+V+D
Sbjct: 428 KNLGTIKCSNLCTEIVEYTSRDEVAVCNLASIALPRFVKDGA------------------ 469
Query: 478 RYFDFEKLGEVTAVVTTNLNKIIDVNYYPVETAERSNLRHRPIGIGVQGLADTFILLGMA 537
FD+ L EVT VVT NLN++ID N+YPV A SNLRHRP+GIGVQGLAD F LL +
Sbjct: 470 --FDYVALKEVTKVVTRNLNRVIDRNHYPVCEARYSNLRHRPVGIGVQGLADAFALLSLP 527
Query: 538 FDSPEAQQLNKDIFETIYYHALKTSCELAAKEGPYETYSGSPVSKGILQPDMW------- 590
F PEA++LN+ IFETIY A++ S ELA K+GPYET+ GSP S+G LQ D+W
Sbjct: 528 FAHPEAKKLNRQIFETIYIAAVEASTELAEKDGPYETFKGSPASEGKLQFDLWDEERRIR 587
Query: 591 GVTPSN------LWDWGALREMISKTGVRNSLLVAPMPTASTSQILGNNECFEPYTSNIY 644
G+ + LWDW +L+E + K G+RNSLL+APMPTASTSQILGNNEC EP+TSNIY
Sbjct: 588 GMNEDSVHSHCGLWDWDSLKERVVKVGMRNSLLIAPMPTASTSQILGNNECIEPFTSNIY 647
Query: 645 NRRVLSGEFVVVNKHLLHDLTEMGLWNPALKNKIIYDNGSVQNLSEIPAELKVIYKTVWE 704
RRVLSGEF VVNKHL+ +L + LWN ++ KII NGSV + EIP ++ +YK VWE
Sbjct: 648 VRRVLSGEFPVVNKHLVKELIRLRLWNDDMRRKIIALNGSVSGIKEIPERIRELYKVVWE 707
Query: 705 IKQKILVDMAVDRGCYIDQSQSLNIHMDKPNFGKLTSLHFYAWSKGLKTGMYYLRTRAAS 764
I+QK L+DMA DRG YIDQSQSLN+ + P +LTS+HFY+W KGLKTGMYYLR++ A+
Sbjct: 708 IRQKDLIDMAADRGRYIDQSQSLNLFLATPTSSQLTSMHFYSWKKGLKTGMYYLRSQPAA 767
Query: 765 DAIKFTVDTSAIKDQPKVKEADDED 789
DAIKFT+D A+K+ PK + E+
Sbjct: 768 DAIKFTLDPKAMKELPKPDKQSKEE 792
>RIR1_ENCCU (Q8SR37) Ribonucleoside-diphosphate reductase large
chain (EC 1.17.4.1) (Ribonucleotide reductase)
Length = 768
Score = 810 bits (2093), Expect = 0.0
Identities = 394/786 (50%), Positives = 546/786 (69%), Gaps = 31/786 (3%)
Query: 9 RQEAVHFDKITARLKKLSYGLSTEHCDPVLVAQKVCAGVYKGVTTSQLDELAAETAAGMT 68
+ E + D I +R++ L H D + +++ +G + +T + + +ETAA M
Sbjct: 11 KSEKLGIDLIRSRIEGYVKDLKLRHVDVDELVERIVSGWCEDMTRKETIDYCSETAASMI 70
Query: 69 ANHPDYASLAARIAVSNLHKNTLKSFSETVKVMYNHFNHRSGKKAPLIADDVYEIIIKNA 128
HP+Y +++RI VS +H+ T+ SF E +K + H ++++++Y II+++
Sbjct: 71 TKHPEYGQISSRIIVSYIHEITMDSFVEKIKYIQKHRG--------MVSEEMYGIILEHG 122
Query: 129 ARLDSEIIYDRDFDYDYFGFKTLERSYLLKVQGVVVERPQHMIMRVSVGIHKDDVESAVK 188
++ I Y+ DF + YFG TL +SYL+KV ++ERPQ M MRV++ IHK D E +
Sbjct: 123 ETIEGMINYENDFLFSYFGILTLMKSYLIKVGEEIIERPQDMFMRVALQIHKTDFEKVRE 182
Query: 189 TYHFMSQRWFTHASPTLFNAGTPRPQLSSCFLVCMKEDSIEGIYDTLKECAVISKSAGGI 248
Y+ +S +FTHA+PTL+N+ PQL+SCFL+ +EDSIEG+Y + + A+I+K +GGI
Sbjct: 183 VYNLLSGHYFTHATPTLYNSCLKNPQLASCFLITPREDSIEGVYHMINQAAIITKYSGGI 242
Query: 249 GVSVHNIRAHGSYIRGTNGTSNGIVPMLRVFNDTARYVDQGGGKRKGAFAVYLEPWHADI 308
G+++H IR+ GS +R T G SNGI+P+++V N T RY++QG +R G+ A++LEPWH +I
Sbjct: 243 GLNLHGIRSKGSSLRSTGGRSNGIIPLIQVLNATKRYINQGAERRPGSIAIFLEPWHMEI 302
Query: 309 FEFLELKINHGKEEQRARDLFYALWVPDLFMERVQSNGEWSLFCPNEAPGLADCWGEEYD 368
F+FLEL+ N G EE RARD+F ALW+ DLFMERV++N EWSLFCP++A GL+D WGEE++
Sbjct: 303 FDFLELRKNTGPEEFRARDIFTALWINDLFMERVKNNEEWSLFCPSQAVGLSDVWGEEFN 362
Query: 369 KLYTQYEKAGKAKKIVQAQSLWFAILKSQIETGNPYMLFKDACNRKSNQQNLGTIKSSNL 428
LY +YEK ++ +V AQ LW AI+++QIETG PYM +KDACNR SNQQ+LGTIKSSNL
Sbjct: 363 ALYCKYEKT-ISRTVVPAQKLWKAIIEAQIETGTPYMCYKDACNRLSNQQHLGTIKSSNL 421
Query: 429 CTEIIEYTSPTETAVCNLASIALPRYVRDKGLPVESHQSKLVGSRGSSSRYFDFEKLGEV 488
C EI+EY+S ET+VCNLASI LP +V+D +FDFE V
Sbjct: 422 CAEIVEYSSGEETSVCNLASICLPMFVKDG--------------------WFDFEAFRRV 461
Query: 489 TAVVTTNLNKIIDVNYYPVETAERSNLRHRPIGIGVQGLADTFILLGMAFDSPEAQQLNK 548
++T NLN++ID NYYPVE A RSN+R+RPIGIGVQGLAD F +L +AF+S A+ LN+
Sbjct: 462 VKILTVNLNRVIDFNYYPVEEARRSNMRNRPIGIGVQGLADLFAILRLAFESDGARSLNQ 521
Query: 549 DIFETIYYHALKTSCELAAKEGPYETYSGSPVSKGILQPDMWGVTPSNLWDWGALREMIS 608
DIFE +YY A++ SCELA KEGP+ +Y GSP+SKGI ++ G S WDW LRE I
Sbjct: 522 DIFEAMYYSAMEASCELAEKEGPFPSYEGSPISKGIFHFELAGRKASGNWDWEGLRERIR 581
Query: 609 KTGVRNSLLVAPMPTASTSQILGNNECFEPYTSNIYNRRVLSGEFVVVNKHLLHDLTEMG 668
+ GVRNSLL+A MPTA TSQI GNNE FEP+ SNIY RR +GEF +VN+HL++DL +G
Sbjct: 582 RHGVRNSLLIALMPTAGTSQIFGNNEAFEPHASNIYTRRTHAGEFQIVNQHLVNDLVRLG 641
Query: 669 LWNPALKNKIIYDNGSVQNLSEIPAELKVIYKTVWEIKQKILVDMAVDRGCYIDQSQSLN 728
LW+ +KN +I + GS+QN++ IP E++ IYKT WEIK K ++D+A DR ++DQSQSLN
Sbjct: 642 LWSYEMKNLVIENEGSIQNITSIPHEIREIYKTAWEIKMKSVIDLAADRQVFVDQSQSLN 701
Query: 729 IHMDKPNFGKLTSLHFYAWSKGLKTGMYYLRTRAASDAIKFTVDTSAIKDQPKVKEADDE 788
I + KP + +LTS+HFY + GLKTGMYYLRTR + AIKFTVD + + +D
Sbjct: 702 IFIAKPTYSQLTSMHFYGYHCGLKTGMYYLRTRPITSAIKFTVDKKLA--EKTLSSMNDT 759
Query: 789 DDDTKM 794
DD M
Sbjct: 760 DDPCSM 765
>RIR1_ASFB7 (P42491) Ribonucleoside-diphosphate reductase large
chain (EC 1.17.4.1) (Ribonucleotide reductase)
Length = 778
Score = 515 bits (1326), Expect = e-145
Identities = 306/749 (40%), Positives = 438/749 (57%), Gaps = 81/749 (10%)
Query: 56 LDELAAETAAGMTANHPDYASLAARIAVSNLHKNTLKSFSETVKVMYNHFNHRSGKKAPL 115
L EL + +A +T H DY++LAAR++V LH++T SFS+ V++ ++ +
Sbjct: 34 LQELISYCSA-LTILHYDYSTLAARLSVYQLHQSTASSFSKAVRL-------QAAQSCSR 85
Query: 116 IADDVYEIIIKNAARLDSEIIYDRDFDYDYFGFKTLERSYLLKVQ-GVVVERPQHMIMRV 174
++ +++ K A DS I Y+RD+ G +T++ SYLLK + GV++ERPQ MRV
Sbjct: 86 LSPQFVDVVYKYKAIFDSYIDYNRDYKLSLLGIETMKNSYLLKNKDGVIMERPQDAYMRV 145
Query: 175 SVGIHKD----DVESAVKTYHFMSQRWFTHASPTLFNAGTPRPQLSSCFLVCMKEDSIEG 230
++ I+ +++ + TY +S+ THASPT+FNAGT +PQLSSCFL+ + D++E
Sbjct: 146 AIMIYGMGKVVNIKMILLTYDLLSRHVITHASPTMFNAGTKKPQLSSCFLLNVN-DNLEN 204
Query: 231 IYDTLKECAVISKSAGGIGVSVHNIRAHGSYIRGTNGTSNGIVPMLRVFNDTARYVDQGG 290
+YD +K +IS GGIG+ + IRA S+I G+ SNGI + + N + Y +QGG
Sbjct: 205 LYDMVKTAGIISGGGGGIGLCLSGIRAKNSFISGSGLRSNGIQNYIMLQNASQCYANQGG 264
Query: 291 GKRKGAFAVYLEPWHADIFEFLELKINHGK-EEQR--ARDLFYALWVPDLFMERVQS--- 344
R GA+AVYLE WH DIF FL++ G+ EQR A +L Y LWVPDLFME ++
Sbjct: 265 -LRPGAYAVYLELWHQDIFTFLQMPRLKGQMAEQRLNAPNLKYGLWVPDLFMEILEDQIH 323
Query: 345 ---NGEWSLFCPNEAPGLADCWG----------EEYDKLYTQYEKAGKAKKIVQAQSLWF 391
+G W LF P++AP L + E+ KLY QY + + A+ +
Sbjct: 324 NRGDGTWYLFSPDQAPNLHKVFDLERSQHENAHREFKKLYYQYVAEKRYTGVTTAKEIIK 383
Query: 392 AILKSQIETGNPYMLFKDACNRKSNQQNLGTIKSSNLCTEIIEYTSP------TETAVCN 445
K+ I+ GNPY+ FKDA NRKSN ++GTI +SNLC IE T P E VCN
Sbjct: 384 EWFKTVIQVGNPYIGFKDAINRKSNLSHVGTITNSNLC---IEVTIPCWEGDKAEQGVCN 440
Query: 446 LASIALPRYVRDKGLPVESHQSKLVGSRGSSSRYFDFEKLGEVTAVVTTNLNKIIDVNYY 505
LA++ L ++R+ G +D+ L E + VT NL+ IID YY
Sbjct: 441 LAAVNLAAFIRENG--------------------YDYRGLIEASGNVTENLDNIIDNGYY 480
Query: 506 PVETAERSNLRHRPIGIGVQGLADTFILLGMAFDSPEAQQLNKDIFETIYYHALKTSCEL 565
P E RSN+RHRPIGIGV GLAD F L M F SPEA +++ I +YY A++ S EL
Sbjct: 481 PTEATRRSNMRHRPIGIGVFGLADVFASLKMKFGSPEAIAMDEAIHAALYYGAMRRSIEL 540
Query: 566 AAKEGPYETYSGSPVSKGILQPDMWGVTP--SNLWD---------------WGALREMIS 608
A ++G + ++ GS SKG+LQPD+W S+ W+ W LR + +
Sbjct: 541 AKEKGSHPSFPGSAASKGLLQPDLWVRCGDLSSSWEERVAQTTQGVLTRKSWWQLR-LAA 599
Query: 609 KTGVRNSLLVAPMPTASTSQILGNNECFEPYTSNIYNRRVLSGEFVVVNKHLLHDLTEMG 668
GVRN L A MPTA++S G NECFEP+TSN+Y RR LSGEF+V+NK+L+ DL E+
Sbjct: 600 MQGVRNGYLTALMPTATSSNSTGKNECFEPFTSNLYTRRTLSGEFIVLNKYLIDDLKEID 659
Query: 669 LWNPALKNKIIYDNGSVQNLSEIPAELKVIYKTVWEIKQKILVDMAVDRGCYIDQSQSLN 728
LW A++ +++ GS+Q++ +IPAE++ YKT E+ QKIL A R ++ QS SLN
Sbjct: 660 LWTEAIQQQLLNAGGSIQHILDIPAEIRDRYKTSREMNQKILTKHAAARNPFVSQSMSLN 719
Query: 729 IHMDKPNFGKLTSLHFYAWSKGLKTGMYY 757
+ +P ++ ++ W KGL TG YY
Sbjct: 720 YYFYEPELSQVLTVLVLGWKKGLTTGSYY 748
>RIR1_ASFM2 (P26685) Ribonucleoside-diphosphate reductase large
chain (EC 1.17.4.1) (Ribonucleotide reductase)
Length = 779
Score = 508 bits (1307), Expect = e-143
Identities = 300/742 (40%), Positives = 430/742 (57%), Gaps = 84/742 (11%)
Query: 65 AGMTANHPDYASLAARIAVSNLHKNTLKSFSETVKVMYNHFNHRSGKKAPLIADDVYEII 124
+ +T H DY++LAAR++V LH++T SFS+ V + ++ + ++ +++
Sbjct: 43 SALTILHYDYSTLAARLSVYLLHQSTASSFSKAVSL-------QAAQSCSRLSSHFVDVV 95
Query: 125 IKNAARLDSEIIYDRDFDYDYFGFKTLERSYLLKVQ-GVVVERPQHMIMRVSVGIHKD-- 181
K A DS I Y RD+ G +T++ SYLLK + GV++ERPQ MRV++ IH
Sbjct: 96 YKYKAIFDSYIDYSRDYKLSLLGIETMKNSYLLKNKDGVIMERPQDAYMRVAIMIHGMGR 155
Query: 182 --DVESAVKTYHFMSQRWFTHASPTLFNAGTPRPQLSSCFLVCMKEDSIEGIYDTLKECA 239
+++ + TY +S+ THASPT+FNAGT +PQLSSCFL+ + D++E +YD +K
Sbjct: 156 VVNMKMILLTYDLLSRHVITHASPTMFNAGTKKPQLSSCFLLNVN-DNLENLYDMVKTAG 214
Query: 240 VISKSAGGIGVSVHNIRAHGSYIRGTNGTSNGIVPMLRVFNDTARYVDQGGGKRKGAFAV 299
+IS GGIG+ + IRA S+I G+ SNGI + + N + Y +QGG R GA+AV
Sbjct: 215 IISGGGGGIGLCLSGIRAKNSFISGSGLRSNGIQNYIVLQNASQCYANQGG-LRPGAYAV 273
Query: 300 YLEPWHADIFEFLELKINHGK-EEQR--ARDLFYALWVPDLFMERVQS------NGEWSL 350
YLE WH DIF FL++ G+ EQR A +L Y LWVPDLFME ++ +G W L
Sbjct: 274 YLELWHQDIFTFLQMPRLKGQMAEQRLNAPNLKYGLWVPDLFMEILEDQIHNRGDGTWYL 333
Query: 351 FCPNEAPGLADCWG----------EEYDKLYTQYEKAGKAKKIVQAQSLWFAILKSQIET 400
F P++AP L + E+ KLY QY + + A+ + K+ ++
Sbjct: 334 FSPDQAPNLHKVFDLERSQHENAHREFKKLYYQYVAEKRYTGVTTAKEIIKEWFKTVVQV 393
Query: 401 GNPYMLFKDACNRKSNQQNLGTIKSSNLCTEIIEYTSP------TETAVCNLASIALPRY 454
GNPY+ FKDA NRKSN ++GTI +SNLC EI T P E VCNLA++ L +
Sbjct: 394 GNPYIGFKDAINRKSNLSHVGTITNSNLCIEI---TIPCWEGNEAEQGVCNLAAVNLAAF 450
Query: 455 VRDKGLPVESHQSKLVGSRGSSSRYFDFEKLGEVTAVVTTNLNKIIDVNYYPVETAERSN 514
+R+ +D+ L E VT NL+ IID YYP E RSN
Sbjct: 451 IRESS--------------------YDYRGLIEAAGNVTENLDNIIDNGYYPTEATRRSN 490
Query: 515 LRHRPIGIGVQGLADTFILLGMAFDSPEAQQLNKDIFETIYYHALKTSCELAAKEGPYET 574
+RHRPIGIGV GLAD F L M F SPEA +++ I +YY A++ S ELA ++G + +
Sbjct: 491 MRHRPIGIGVFGLADVFASLKMKFGSPEAIAIDEAIHAALYYGAMRRSIELAKEKGSHPS 550
Query: 575 YSGSPVSKGILQPDMW----GVTPSNLWD---------------WGALREMISKTGVRNS 615
+ GS SKG+LQPD+W + PS W+ W LR + + GVRN
Sbjct: 551 FPGSAASKGLLQPDLWVRCGDLIPS--WENRVAQTTQGVLTPKKWWQLR-LAAIQGVRNG 607
Query: 616 LLVAPMPTASTSQILGNNECFEPYTSNIYNRRVLSGEFVVVNKHLLHDLTEMGLWNPALK 675
L A MPTA++S G NECFEP+TSN+Y RR LSGEF+++NK+L+ DL E+ LW+ ++
Sbjct: 608 YLTALMPTATSSNSTGKNECFEPFTSNLYTRRTLSGEFIILNKYLMDDLEEINLWSEDIQ 667
Query: 676 NKIIYDNGSVQNLSEIPAELKVIYKTVWEIKQKILVDMAVDRGCYIDQSQSLNIHMDKPN 735
+++ GS+Q++ +IPAE++ YKT E+ QKIL A R ++ QS SLN + +P
Sbjct: 668 QQLLNAGGSIQHILDIPAEIRERYKTSREMNQKILTKHAAARNPFVSQSMSLNYYFYEPE 727
Query: 736 FGKLTSLHFYAWSKGLKTGMYY 757
++ ++ W KGL TG YY
Sbjct: 728 LSQVLTVLVLGWKKGLTTGSYY 749
>RIR1_CHLTR (O84834) Ribonucleoside-diphosphate reductase alpha chain
(EC 1.17.4.1) (Ribonucleotide reductase)
Length = 1047
Score = 481 bits (1239), Expect = e-135
Identities = 297/840 (35%), Positives = 456/840 (53%), Gaps = 64/840 (7%)
Query: 3 VVKRDGRQEAVHFDKITARLKKLSYGLSTEHCDPVLVAQKVCAGVYKGVTTSQLDELAAE 62
V+ +DG + ++ A L + + E D L+ A Y G+ S++
Sbjct: 239 VLSKDGSTYTMTHSQLLAHLAR-ACSRFPETTDAALLTDMAFANFYSGIKESEVVLACIM 297
Query: 63 TAAGMTANHPDYASLAARIAVSNLHKNTL--KSFSETVKVMYNHFNHRSGKKAPLIADDV 120
A PDYA +AA + + ++K L ++E ++ HR K + D
Sbjct: 298 AARANIEKEPDYAFVAAELLLDVVYKEALGKSKYAEDLEQA-----HRDHFKRYIAEGDT 352
Query: 121 YEIIIKNAARLDSEIIYD-----RDFDYDYFGFKTLERSYLLKVQGVVVERPQHMIMRVS 175
Y + + D + + D RD + Y G + L Y +G +E PQ MRV+
Sbjct: 353 YRLNAELKHLFDLDALADAMDLSRDLQFSYMGIQNLYDRYFNHHEGCRLETPQIFWMRVA 412
Query: 176 VGI---HKDDVESAVKTYHFMSQRWFTHASPTLFNAGTPRPQLSSCFLVCMKEDSIEGIY 232
+G+ +D A+ Y+ +S +T A+PTLFN+G QLSSC+L + +D++ IY
Sbjct: 413 MGLALNEQDKTSWAITFYNLLSTFRYTPATPTLFNSGMRHSQLSSCYLSTV-QDNLVNIY 471
Query: 233 DTLKECAVISKSAGGIGVSVHNIRAHGSYIRGTNGTSNGIVPMLRVFNDTARYVDQGGGK 292
+ + A++SK AGGIG IRA G+ I+GTNG S G++P ++V NDTA V+QGG K
Sbjct: 472 KVIADNAMLSKWAGGIGNDWTAIRATGALIKGTNGRSQGVIPFIKVTNDTAVAVNQGG-K 530
Query: 293 RKGAFAVYLEPWHADIFEFLELKINHGKEEQRARDLFYALWVPDLFMERVQSNGEWSLFC 352
RKGA VYLE WH D +FLEL+ N G E +RA D+ A W+PDLF +R+Q G W+LF
Sbjct: 531 RKGAVCVYLEVWHLDYEDFLELRKNTGDERRRAHDVNIASWIPDLFFKRLQQKGTWTLFS 590
Query: 353 PNEAPGLADCWGEEYDKLYTQYEK---AGKAK--KIVQAQSLWFAILKSQIETGNPYMLF 407
P++ PGL D +GEE+++LY +YE+ G+ + K V+A+ LW +L ETG+P+M F
Sbjct: 591 PDDVPGLHDAYGEEFERLYEEYERKVDTGEIRLFKKVEAEDLWRKMLSMLFETGHPWMTF 650
Query: 408 KDACNRKSNQQNLGTIKSSNLCTEIIEYTSPTETAVCNLASIALPRYVRDKGLPVESHQS 467
KD N +S Q + G ++ SNLCTEI+ S TETAVCNL SI L +++ GL
Sbjct: 651 KDPSNIRSAQDHKGVVRCSNLCTEILLNCSETETAVCNLGSINLVQHIVGDGL------- 703
Query: 468 KLVGSRGSSSRYFDFEKLGEVTAVVTTNLNKIIDVNYYPVETAERSNLRHRPIGIGVQGL 527
D EKL E ++ L+ +ID+N+YP + A+ +N HR IG+GV G
Sbjct: 704 -------------DEEKLSETISIAVRMLDNVIDINFYPTKEAKEANFAHRAIGLGVMGF 750
Query: 528 ADTFILLGMAFDSPEAQQLNKDIFETIYYHALKTSCELAAKEGPYETYSGSPVSKGILQP 587
D L +++ S EA + E I Y+A++ SC LA + G Y +Y GS +G+L
Sbjct: 751 QDALYKLDISYASQEAVEFADYSSELISYYAIQASCLLAKERGTYSSYKGSKWDRGLLPI 810
Query: 588 DM------------WGVTPSNLWDWGALREMISKTGVRNSLLVAPMPTASTSQILGNNEC 635
D + S+ DW +R ++ + G+R+ L+A PTA+ S I+G +
Sbjct: 811 DTIQLLANYRGEANLQMDTSSRKDWEPIRSLVKEHGMRHCQLMAIAPTATISNIIGVTQS 870
Query: 636 FEPYTSNIYNRRVLSGEFVVVNKHLLHDLTEMGLWNPALKNKIIYDNGSVQNLSEIPAEL 695
EP +++ + LSGEF + N +L+ L ++G+W+ + + + Y +GS+ + IP L
Sbjct: 871 IEPTYKHLFVKSNLSGEFTIPNVYLIEKLKKLGIWDADMLDDLKYFDGSLLEIERIPDHL 930
Query: 696 KVIYKTVWEIKQKILVDMAVDRGCYIDQSQSLNIHMDKPNFGKLTSLHFYAWSKGLKTGM 755
K I+ T +EI+ + +++ A R +ID QSLN+++ +P+ KL++++ AW KGLKT
Sbjct: 931 KHIFLTAFEIEPEWIIECASRRQKWIDMGQSLNLYLAQPDGKKLSNMYLTAWKKGLKT-T 989
Query: 756 YYLRTRAASDAIKFTVDTSAIKDQP-----KVKEADDEDDDTKMAQMVCSLTNRDECEAC 810
YYLR+ +A+ K VD + QP K A + K A VCSL + CEAC
Sbjct: 990 YYLRSSSATTVEKSFVDINKRGIQPRWMKNKSASAGIIVERAKKAP-VCSL--EEGCEAC 1046
Database: sprot
Posted date: Nov 25, 2004 10:54 AM
Number of letters in database: 59,974,054
Number of sequences in database: 164,201
Lambda K H
0.318 0.134 0.399
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 95,973,088
Number of Sequences: 164201
Number of extensions: 4148556
Number of successful extensions: 10283
Number of sequences better than 10.0: 61
Number of HSP's better than 10.0 without gapping: 52
Number of HSP's successfully gapped in prelim test: 9
Number of HSP's that attempted gapping in prelim test: 9910
Number of HSP's gapped (non-prelim): 79
length of query: 812
length of database: 59,974,054
effective HSP length: 118
effective length of query: 694
effective length of database: 40,598,336
effective search space: 28175245184
effective search space used: 28175245184
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 70 (31.6 bits)
Medicago: description of AC135232.5