BLAST2 result
BLASTP 2.2.2 [Dec-14-2001]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= AC133341.11 + phase: 0 /partial
(1497 letters)
Database: sprot
164,201 sequences; 59,974,054 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
MYSJ_DICDI (P54697) Myosin IJ heavy chain 744 0.0
MY5A_CHICK (Q02440) Myosin Va (Myosin 5A) (Dilute myosin heavy c... 680 0.0
MY5A_HUMAN (Q9Y4I1) Myosin Va (Myosin 5A) (Dilute myosin heavy c... 671 0.0
MY5A_MOUSE (Q99104) Myosin Va (Myosin 5A) (Dilute myosin heavy c... 669 0.0
MY5A_RAT (Q9QYF3) Myosin Va (Myosin 5A) (Dilute myosin heavy cha... 669 0.0
MY5B_HUMAN (Q9ULV0) Myosin Vb (Myosin 5B) 659 0.0
MY5B_RAT (P70569) Myosin Vb (Myosin 5B) (Myosin heavy chain myr 6) 656 0.0
MY2A_SACCA (Q875X3) Myosin-2A (Class V unconventional myosin MYO... 655 0.0
MYS2_SACKL (Q875Q8) Myosin-2 (Class V unconventional myosin MYO2... 650 0.0
MYS2_YEAST (P19524) Myosin-2 (Class V unconventional myosin MYO2... 650 0.0
MYS2_SACBA (Q876G9) Myosin-2 (Class V unconventional myosin MYO2... 641 0.0
MYS4_YEAST (P32492) Myosin-4 isoform 635 0.0
MYS2_DICDI (P08799) Myosin II heavy chain, non muscle 629 e-179
MY5C_HUMAN (Q9NQX4) Myosin Vc (Myosin 5C) 622 e-177
MY2B_SACCA (Q875X4) Myosin-2B (Class V unconventional myosin MYO... 615 e-175
MY52_SCHPO (O94477) Myosin 52 (Myosin type V-2) 609 e-173
MYSN_ACACA (P05659) Myosin II heavy chain, non muscle 608 e-173
MY51_SCHPO (O74805) Myosin 51 (Myosin type V-1) 583 e-165
MY7A_MOUSE (P97479) Myosin VIIa 558 e-158
MY7A_HUMAN (Q13402) Myosin VIIa 558 e-158
>MYSJ_DICDI (P54697) Myosin IJ heavy chain
Length = 2245
Score = 744 bits (1921), Expect = 0.0
Identities = 460/1215 (37%), Positives = 696/1215 (56%), Gaps = 129/1215 (10%)
Query: 9 GTHVWIEDSDIAWIDGEVVG---VNGEEIKVLCTSGKTVVVKASKIYHKDTEVPPSGVDD 65
G VWI D ++ WI +V+ + +++ V + V + SK++ K+ ++ GVDD
Sbjct: 27 GAGVWIPDQELGWIGADVIEHSETSADQVLVRTEDDREVKIPLSKVFQKNPDIL-EGVDD 85
Query: 66 MTKLAYLHEPGVLNNLRSRYDINEIYTYTGNILIAVNPFIKLPHLYDIHMMAQYKGVAFG 125
++ L++LHEP +L+NL RY++N+IYTY G ILIA+NP+ LP LY M++ Y G G
Sbjct: 86 LSFLSHLHEPAILHNLHHRYNLNQIYTYIGKILIAINPYTSLP-LYGKEMISAYYGKQLG 144
Query: 126 ELSPHPFAVADAAYRLMINEGISQSILVSGESGAGKTETTKLLMRYLAYMG--------- 176
L+PH +AVA+ A++ M +G SQSILVSGESGAGKTETTK L++YLA MG
Sbjct: 145 TLAPHVYAVAEDAFKDMRYDGTSQSILVSGESGAGKTETTKFLLQYLAAMGNMIKESTSS 204
Query: 177 ----GRAAVAEG----------------RTVEQKVLESNPVLEAFGNAKTVRNNNSSRFG 216
G ++G ++VE++VLES P+LEAFGNAKT+RN+NSSRFG
Sbjct: 205 SSINGINTSSDGIPVTPPPSPMKKSPVDKSVEERVLESTPLLEAFGNAKTLRNDNSSRFG 264
Query: 217 KFVEIQFDQKGRISGAAIRTYLLERSRVCQLSDPERNYHCFYMLCAAPAEVVK-KYKLGH 275
KF+EI F++ G I GA I YLLE+S + + ERNYH FY L + +E +K K L
Sbjct: 265 KFIEIHFNEMGSIIGAKILAYLLEKSGIVRQVYNERNYHIFYQLLSGASEELKEKLNLKT 324
Query: 276 PRTFHYLNQSNCYELEGLDESKEYITIRRAMDVVGISIENQDAIFQVVAAILHLGNIEF- 334
+ YLN+S C+E+EG+ + + + AM V GI++ Q+ +F++++AIL +GN EF
Sbjct: 325 IEEYSYLNKSGCFEIEGVSDEEHFNKTCHAMQVAGITLVEQENVFRILSAILLIGNFEFE 384
Query: 335 -VKGDEIDSSMPKDEKSRFHLQTAAELFMC-DANALEDSLCKRVIVTRDETITKWLDPEA 392
+ G DS D R L+ + L C + L +S+ R +VT E+ E
Sbjct: 385 NIAGSNDDSCQLID---RDPLEKVSVLLGCAQPDELLNSMLTRKVVTGKESYISHNTKER 441
Query: 393 AALSRDALAKIVYTRLFDWLVDTINNS--IGQDPESKSLIGVLDIYGFESFKNNSFEQFC 450
A +RD+L+ +Y +FDWLV IN+S I +SKS IGVLDIYGFESF+ N FEQFC
Sbjct: 442 AENARDSLSMFLYGMMFDWLVVKINSSMSISTQQKSKSFIGVLDIYGFESFEVNGFEQFC 501
Query: 451 INLTNEKLQQHFNQHVFKMEQEEYKKEEIDWSYIEFVDNQDILDLIEKKPGGIISLLDEA 510
IN NEKLQQ FNQHVFK EQ+EY KE+IDWSYI+F DNQD LDLIEK P I++LLDE
Sbjct: 502 INYANEKLQQLFNQHVFKEEQQEYIKEKIDWSYIDFNDNQDTLDLIEKNPICILTLLDEE 561
Query: 511 CMFPRSTHETFSQKLYQTFKDHKRFSKPKLSPSDFTICHYAGDVTYQTEYFLDKNKDYVV 570
MFP++T +T + KLY H +F KP+ S + FTI HYAG VTY+T+ FLDKNKD+++
Sbjct: 562 TMFPKATPQTLATKLYSKMTSHSKFEKPRFSSTAFTINHYAGKVTYETDQFLDKNKDFII 621
Query: 571 AEHQSLLYASTCPFVSGLFPPSPEET-----------------------SKQSKFSSIGS 607
E S+L S F+ L S + T S KF S+GS
Sbjct: 622 PEQISILQRSNFSFIKVLMSHSDKFTQSPGGHPQGNGGPTSSNTKGTSGSSSMKFLSVGS 681
Query: 608 RFKQQLQSLLETLSSTEPHYIRCVKPNNLLKPAIFDNKNVLLQLRCGGVMEAIRISCAGY 667
+F L +L++T+S+T PHY+RC+KPN P F+ ++V+ QLRCGGVME++RI CAG+
Sbjct: 682 QFSTSLATLMKTISTTTPHYVRCIKPNPEKLPQTFNKQDVIHQLRCGGVMESVRICCAGF 741
Query: 668 PTRKAFDEFVDRFGLLAPEVLD--------GSSEEVTACKRILKNVWLEG-------YQI 712
PTR+ EF R+ +L + ++ GS+ +IL L G Y+I
Sbjct: 742 PTRRLLSEFYQRYKILYVKDINTGSGGGKKGSNNNKIKDPKILVQNLLTGIELSDDKYKI 801
Query: 713 GKTKVFLRAGQMAELDTRRSEILGKSASIIQRKVRSYLARQSFILLRVSALQIQAACRGQ 772
G TKVFLRAGQ+A L+ R E L +SA++IQ++ + YL R+ + LR ++L IQ R
Sbjct: 802 GLTKVFLRAGQLASLEDMRLEQLDRSATVIQKRWKGYLYRKRYKQLRDASLIIQTKLRSV 861
Query: 773 LARQVFEGMRREASSLLIQRCLRMHIAKKAYKELYASAVSIQTGMRVMAAHCELHSRRRT 832
A+ ++R S++LIQ+ R H + Y+++ +++ +QT MR ++H R
Sbjct: 862 HAKHHLSALQRTHSAILIQKVWRAHRDRVQYQKIRDASLQLQTVMRRHLFSEQVHRERCE 921
Query: 833 SAAIIIQSHCRKYLALLNFTKLKKAAIATQCAWRGKVARRELRKLKMAARETGALQDAKN 892
+AAII+Q+ R+ L+ K + I Q WR K+A+R +L+ AR +Q+ KN
Sbjct: 922 NAAIILQTKIRQILSKREVDKKLRGIILIQARWRMKLAKRVYIQLRAEARSLRTVQEQKN 981
Query: 893 KLEKQVEDLTLRLQLEKRLRVDVEEAKAK----------ENERLQSALQKMQLQFKETKV 942
KL++++E+L RL E + + +E+ K K N+ L+ L ++QL+++E
Sbjct: 982 KLQEKLEELQWRLTSEAKRKQQLEDQKVKSDTTISELSSNNDHLELQLSEIQLKYQELDN 1041
Query: 943 LLEKER----EATKKLEARVPVIQEVPAVDHALLEKLSSEN---EKLKTLVSSLEKKIDE 995
+ + E KLE + + ++ L + LS ++ EKL++ + E+++ +
Sbjct: 1042 SNQSSQLQLSECLSKLEEQTQQLDHSSKLNKKLEKDLSDQHDSIEKLQSQFNETEQQLQQ 1101
Query: 996 TEKRYEE-EAKVSE------------ERLKQALDAES-----KVIQMKTAMQRLEEKFAD 1037
+++ EE +K+S+ +RL Q D ++ ++ Q+K A LEE +
Sbjct: 1102 FKQQSEELSSKLSKTTQQLDFNKQEFDRLSQERDTDNTNNQLEIQQLKKANSTLEEDYFS 1161
Query: 1038 IEFANHVLQKQSLSI---NSPVKTAVENLSTPVSEKLENGHHVAEEPYDADTYVTPVKQF 1094
+ L++Q L + N +K +++L S + ++G + ++ ++Q
Sbjct: 1162 LSGIRDNLERQVLELRDENQLIKERLDSLGQQ-SSQFQSGAALEKQ---------QLEQL 1211
Query: 1095 VAESDVKLKRSCSER 1109
V E +L + SE+
Sbjct: 1212 VQEQSEQLIKLSSEK 1226
Score = 72.8 bits (177), Expect = 7e-12
Identities = 131/629 (20%), Positives = 261/629 (40%), Gaps = 88/629 (13%)
Query: 889 DAKNKLEKQVEDLTLRLQ--LEKRLRVDVEEAKAKENE--RLQSALQKMQLQFKETKVLL 944
D K + ++ +E L Q L++ +D K KENE +LQ L+ Q + K L
Sbjct: 1621 DMKQRNQELIESSALYKQQLLQQTSTID-STIKEKENEISKLQQQLETSNQQLHQLKEEL 1679
Query: 945 EKEREATKKLEARVPVIQEVPAVDHALLEKLSSENEKLKTLVSSLEKKIDE--------- 995
+++ + LE+ Q L +L EN++LK++ + + K++D+
Sbjct: 1680 NSMKQSNQ-LESTEQSKQ---------LNQLIQENQQLKSVTNEISKQLDDAVFENQKIN 1729
Query: 996 -TEKRYEEEAKVSEERLKQALDA--ESKVIQMKTAMQRLEEKFADIEFANHVLQKQSLSI 1052
T K E ++K L+Q +D + ++ Q+++ + +L+++ + L+K+ +
Sbjct: 1730 NTIKEQEIKSKRMSVELQQHIDEGKQQEIQQLQSTIAQLKQQQ---QSETDRLEKEIQQM 1786
Query: 1053 NSPVKTAVENLSTPVSEKLENGHHVAEEPYDADTYVTPVKQFVAESDVKLKR--SCSERH 1110
+T ++ + E + +H+ E+ + V + + KL R C E
Sbjct: 1787 KRERETQMK-----LVESTKLNYHMLEDRMELYRNVMEIIDYKETEWEKLARLAGCKELD 1841
Query: 1111 HGSF-DSLVNCVSKNIGFNHGKPIAAFTIYKCLLHWKSFEAERSS-VFDRLIQ-MIGSAI 1167
D L++C ++ + + + + +W +E + S +F +I+ ++ I
Sbjct: 1842 TKLLSDFLLSCKLEHTS------LGSQMWFHQIDYWCPYERDSSKGIFYGIIRSIVDFTI 1895
Query: 1168 EDQDDNALMAYWLSNTSALLFLLEQSLKTGTSTNATPNGKPPNPT-----SLFGRMTKSF 1222
++ DD L++Y L+ S LFL +++L N + P PT L R++
Sbjct: 1896 KNFDDVDLLSYLLACCSLTLFLYKKNLVK--HLNGANSIMPIIPTLGDLEELNERLSHQS 1953
Query: 1223 LSSPSSANLASPSSVVRKVEAKYPA------LLFKQQLTAYLEKIYG-IIRDNLTKELTS 1275
L++ + + ++ + L+FK + G I+ +N K+LTS
Sbjct: 1954 LTTSGKFSGGGGGGGIDFIDQLQQSTGITFGLIFKATTLKLSPLVDGAILNENYNKKLTS 2013
Query: 1276 ALALCIQAPRTSKGVLRSGRSFGKDSPMVHWQSIIESLNTLLCTL----KENFIPPVLIR 1331
I A G SFG S V IE + T L ++ + + L +
Sbjct: 2014 -----ISASSFGSG------SFGLGSNGVGSVLSIELITTYLSSIITIFQHRMVHFTLSQ 2062
Query: 1332 KIFSQTFAFINVQLFN-----------SNGEYVKAGLAELELWCCQAKEEYAGSSWDELK 1380
+ F+Q F +I + + +VK + L W + G + +
Sbjct: 2063 RFFNQVFCWIGALIMKGFMLRQTFCTETFATFVKTKIDFLTRWADDIGNVWVGDVANAFQ 2122
Query: 1381 HIRQAVGFLVIHQKYRISYDEIVNDLCPILSVQQLCKICTLYWDDNYNTRSVSPHVLASM 1440
+R+ + L I K +I D+I CP L+ QL ++ +L+ + + VS V+AS+
Sbjct: 2123 QVREVINVLNIKDKEKIIDDKIRKQYCPTLNSNQLKQVLSLFSPGEFGGKRVSAKVIASI 2182
Query: 1441 RMDLDSNDAMNDSFLLDDSSSIPFSVDDL 1469
+ + SF+ D++ +D L
Sbjct: 2183 CP--PNKSSAGQSFVQDENKLNTIPIDSL 2209
Score = 43.9 bits (102), Expect = 0.003
Identities = 52/276 (18%), Positives = 125/276 (44%), Gaps = 49/276 (17%)
Query: 877 LKMAARETGALQDAK---NKLEKQVEDLTLRLQLEKRLRVDVEEAKAKENERLQSALQKM 933
+K+++ + G+ ++AK N+LE ++ D +LQ++ +L E ++ ++L+ L++
Sbjct: 1220 IKLSSEKLGSEEEAKKQINQLELELTDHKSKLQIQLQLT----EQSNEKIKKLKGKLEEY 1275
Query: 934 QLQFKETKVLLEKEREATKKLE----ARVPVIQEVPAVDHALLEKLSSENEKLKTLVSSL 989
Q + K+ + LE+ +++ + +E + + + V + +S + EK+ TL S++
Sbjct: 1276 QDEKKQLQQELERIKQSKQSVEDEKNSLITQLTTVKFESTQVSTNVSHQKEKITTLKSTI 1335
Query: 990 EK------KIDETEKRYEEEAKVSEERL---KQALDAESKVIQMKTAMQRLEEKFADIEF 1040
E+ K+ +K ++E + + L KQ ++K + Q ++ ++I
Sbjct: 1336 EELNKSIGKLQAEQKNKDDEIRKIQFELNDQKQQFTRQTKEFSDLQSQQSIDRPKSEITI 1395
Query: 1041 ANHVLQKQSLSINSPVKTAVENLS-----------------------TPVSEKLENGHHV 1077
H L++ + ++ S + ++L T + E+ EN V
Sbjct: 1396 --HSLERTNETLKSDFERVQQSLKQQERDCQQYKDTINRLENEVKQLTQLKERFENEFFV 1453
Query: 1078 AEEPYDADT----YVTPVKQFVAESDVKLKRSCSER 1109
A+E T Y+ V + ++ +++R E+
Sbjct: 1454 AKEQNSNQTQESVYLKEVTTQMQQNQSRIERELEEK 1489
Score = 36.6 bits (83), Expect = 0.53
Identities = 30/140 (21%), Positives = 67/140 (47%), Gaps = 20/140 (14%)
Query: 875 RKLKMAARETGALQDAKNKLEKQVEDLTLRLQL-----------EKRLRVD----VEEAK 919
++L +E L+ N++ KQ++D Q KR+ V+ ++E K
Sbjct: 1695 KQLNQLIQENQQLKSVTNEISKQLDDAVFENQKINNTIKEQEIKSKRMSVELQQHIDEGK 1754
Query: 920 AKENERLQSALQKMQLQFKETKVLLEKE-REATKKLEARVPVIQEVPAVDHALLEKLSSE 978
+E ++LQS + +++ Q + LEKE ++ ++ E ++ +++ H L +++
Sbjct: 1755 QQEIQQLQSTIAQLKQQQQSETDRLEKEIQQMKRERETQMKLVESTKLNYHMLEDRM--- 1811
Query: 979 NEKLKTLVSSLEKKIDETEK 998
E + ++ ++ K E EK
Sbjct: 1812 -ELYRNVMEIIDYKETEWEK 1830
>MY5A_CHICK (Q02440) Myosin Va (Myosin 5A) (Dilute myosin heavy chain,
non-muscle) (Myosin heavy chain P190) (Myosin-V)
Length = 1829
Score = 680 bits (1755), Expect = 0.0
Identities = 422/1099 (38%), Positives = 617/1099 (55%), Gaps = 85/1099 (7%)
Query: 12 VWIEDSDIAWIDGEVVGVNGEEIKVL---CTSGKTVVVKASKIYHKDTEVPPS------- 61
VWI D + W E++ KVL GK + K E+PP
Sbjct: 13 VWIPDPEEVWKSAELLKDYKPGDKVLQLRLEEGKDLEYCLDP---KTKELPPLRNPDILV 69
Query: 62 GVDDMTKLAYLHEPGVLNNLRSRY-DINEIYTYTGNILIAVNPFIKLPHLYDIHMMAQYK 120
G +D+T L+YLHEP VL+NL+ R+ D IYTY G +L+A+NP+ +LP +Y ++ Y
Sbjct: 70 GENDLTALSYLHEPAVLHNLKVRFIDSKLIYTYCGIVLVAINPYEQLP-IYGEDIINAYS 128
Query: 121 GVAFGELSPHPFAVADAAYRLMINEGISQSILVSGESGAGKTETTKLLMRYLAYMGGRAA 180
G G++ PH FAVA+ AY+ M + +QSI+VSGESGAGKT + K MRY A + G A+
Sbjct: 129 GQNMGDMDPHIFAVAEEAYKQMARDERNQSIIVSGESGAGKTVSAKYAMRYFATVSGSAS 188
Query: 181 VAEGRTVEQKVLESNPVLEAFGNAKTVRNNNSSRFGKFVEIQFDQKGRISGAAIRTYLLE 240
A VE+KVL SNP++E+ GNAKT RN+NSSRFGK++EI FD++ RI GA +RTYLLE
Sbjct: 189 EAN---VEEKVLASNPIMESIGNAKTTRNDNSSRFGKYIEIGFDKRYRIIGANMRTYLLE 245
Query: 241 RSRVCQLSDPERNYHCFYMLCAAPA-EVVKKYKLGHPRTFHYLNQSNCYELEGLDESKEY 299
+SRV ++ ERNYH FY LCA+ A K +LG+ FHY Q ++G+D++KE
Sbjct: 246 KSRVVFQAEEERNYHIFYQLCASAALPEFKTLRLGNANYFHYTKQGGSPVIDGIDDAKEM 305
Query: 300 ITIRRAMDVVGISIENQDAIFQVVAAILHLGNIEFVKGDEIDSSMPKDEKSRFHLQTAAE 359
+ R+A ++GIS Q IF+++A ILHLGN+EF D ++P L +
Sbjct: 306 VNTRQACTLLGISDSYQMGIFRILAGILHLGNVEFASRDSDSCAIPPKHDP---LTIFCD 362
Query: 360 LFMCDANALEDSLCKRVIVTRDETITKWLDPEAAALSRDALAKIVYTRLFDWLVDTINNS 419
L D + LC R + T ET K + A +RDALAK +Y LF+W+VD +N +
Sbjct: 363 LMGVDYEEMAHWLCHRKLATATETYIKPISKLHAINARDALAKHIYANLFNWIVDHVNKA 422
Query: 420 IGQDPESKSLIGVLDIYGFESFKNNSFEQFCINLTNEKLQQHFNQHVFKMEQEEYKKEEI 479
+ + S IGVLDIYGFE+F+ NSFEQFCIN NEKLQQ FN HVFK+EQEEY KE+I
Sbjct: 423 LHSTVKQHSFIGVLDIYGFETFEINSFEQFCINYANEKLQQQFNMHVFKLEQEEYMKEQI 482
Query: 480 DWSYIEFVDNQDILDLIEKKPGGIISLLDEACMFPRSTHETFSQKLYQTFKDH-KRFSKP 538
W+ I+F DNQ ++LIE K G++ LLDE C P+ + +T++QKLY T + F KP
Sbjct: 483 PWTLIDFYDNQPCINLIEAKM-GVLDLLDEECKMPKGSDDTWAQKLYNTHLNKCALFEKP 541
Query: 539 KLSPSDFTICHYAGDVTYQTEYFLDKNKDYVVAEHQSLLYAS------------------ 580
+LS F I H+A V YQ E FL+KNKD V E +L +S
Sbjct: 542 RLSNKAFIIKHFADKVEYQCEGFLEKNKDTVYEEQIKVLKSSKKFKLLPELFQDEEKAIS 601
Query: 581 -TCPFVSGLFPPS----------PEETSKQSKFSSIGSRFKQQLQSLLETLSSTEPHYIR 629
T SG P S P +TSK+ K ++G +F+ L L+ETL++T PHY+R
Sbjct: 602 PTSATPSGRVPLSRTPVKPAKARPGQTSKEHK-KTVGHQFRNSLHLLMETLNATTPHYVR 660
Query: 630 CVKPNNLLKPAIFDNKNVLLQLRCGGVMEAIRISCAGYPTRKAFDEFVDRFGLLAPEVLD 689
C+KPN+ P FD K + QLR GV+E IRIS AG+P+R + EF R+ +L + D
Sbjct: 661 CIKPNDFKFPFTFDEKRAVQQLRACGVLETIRISAAGFPSRWTYQEFFSRYRVLMKQ-KD 719
Query: 690 GSSEEVTACKRILKNVWL--EGYQIGKTKVFLRAGQMAELDTRRSEILGKSASIIQRKVR 747
S+ CK +L+ + L + YQ GKTK+F RAGQ+A L+ R++ L + IQ+ +R
Sbjct: 720 VLSDRKQTCKNVLEKLILDKDKYQFGKTKIFFRAGQVAYLEKIRADKLRAACIRIQKTIR 779
Query: 748 SYLARQSFILLRVSALQIQAACRGQLARQVFEGMRREASSLLIQRCLRMHIAKKAYKELY 807
+L R+ ++ +R +A+ IQ RG AR +RR ++++IQ+ RM++ +K Y+ +
Sbjct: 780 GWLMRKKYMRMRRAAITIQRYVRGHQARCYATFLRRTRAAIIIQKFQRMYVVRKRYQCMR 839
Query: 808 ASAVSIQTGMRVMAAHCELHSRRRTSAAIIIQSHCRKYLALLNFTKLKKAAIATQCAWRG 867
+ +++Q +R + R +IIIQ H R +LA +++ + KA + QC +R
Sbjct: 840 DATIALQALLRGYLVRNKYQMMLREHKSIIIQKHVRGWLARVHYHRTLKAIVYLQCCYRR 899
Query: 868 KVARRELRKLKMAARETGALQDAKNKLEKQVEDLTLRLQ---------LEK--------- 909
+A+REL+KLK+ AR + LE ++ L ++ LEK
Sbjct: 900 MMAKRELKKLKIEARSVERYKKLHIGLENKIMQLQRKIDEQNKEYKSLLEKMNNLEITYS 959
Query: 910 ----RLRVDVEEAKAKENERLQSALQKMQLQFKETKVLLEKEREATKKLEARVPVIQEVP 965
+LR DVE + E E + + + LQ + K+ E + T+K + +
Sbjct: 960 TETEKLRSDVERLRMSEEEAKNATNRVLSLQEEIAKLRKELHQTQTEK-KTIEEWADKYK 1018
Query: 966 AVDHALLEKLSSENEKLKTLVSSLEKKIDETEKRYEE--EAKVSEERLKQALDAESKVIQ 1023
L+ +L +N LKT L ++I + K E E K+ EE + LD + ++
Sbjct: 1019 HETEQLVSELKEQNTLLKTEKEELNRRIHDQAKEITETMEKKLVEETKQLELDLNDERLR 1078
Query: 1024 MKTAM---QRLEEKFADIE 1039
+ + RLEE++ D++
Sbjct: 1079 YQNLLNEFSRLEERYDDLK 1097
Score = 54.3 bits (129), Expect = 2e-06
Identities = 133/655 (20%), Positives = 260/655 (39%), Gaps = 74/655 (11%)
Query: 847 ALLNFTKLKKAAIATQCAWRGKVARRELRKLKMAARETGALQ------DAKNKLEKQVED 900
A L + LK+ + ++ K + EL +L+ A ET A + A L Q+
Sbjct: 1200 AELEYESLKRQELESE----NKKLKNELNELQKALTETRAPEVTAPGAPAYRVLLDQLTS 1255
Query: 901 LTLRLQLEKRLRVDVEEAKAKENERLQSALQKMQLQFKETKVLLEKEREATKKLEARVPV 960
++ L++ K + + + E +Q K + ++ +LLE ++ K E
Sbjct: 1256 VSEELEVRKEEVLILRSQLVSQKEAIQPKEDKNTMT--DSTILLEDVQKMKDKGEIAQAY 1313
Query: 961 IQEVPAVDHALLEKLSSENEKLKTLVSSLEKKIDETEKRYEEEAKVSEERLKQALDAESK 1020
I + + L +L S+ + + + SL +I ++ + ++ + L+ +A +
Sbjct: 1314 IG-LKETNRLLESQLQSQKKSHENELESLRGEIQSLKEENNRQQQLLAQNLQLPPEARIE 1372
Query: 1021 VIQMKTAMQRLEEKFADIEFANHVLQKQSLSINSPVKTAVENLSTPVSEKLENGHHVAEE 1080
++ + RL + D+ L+KQ ++ +K ++ + + E LE G
Sbjct: 1373 A-SLQHEITRLTNENLDLM---EQLEKQDKTVRK-LKKQLKVFAKKIGE-LEVGQMENIS 1426
Query: 1081 PYDA-DTYVTPVKQFVAESDVK--LKRSCSERHHGSFDSLVNCVSKNIGFNHGKPIAAFT 1137
P D + PV E D + L+ + + ++ + + N + A+
Sbjct: 1427 PGQIIDEPIRPVNIPRKEKDFQGMLEYKKEDEQKLVKNLILELKPRGVAVNLIPGLPAYI 1486
Query: 1138 IYKCLLH--WKSFEAERSSVFDRLIQMIGSAIEDQ-DDNALMAYWLSNTSALLFLLEQ-S 1193
++ C+ H + + + + S+ I I ++ + DD +++WLSNT L L+Q S
Sbjct: 1487 LFMCVRHADYLNDDQKVRSLLTSTINGIKKVLKKRGDDFETVSFWLSNTCRFLHCLKQYS 1546
Query: 1194 LKTGTSTNATPNGKPPNPTSLFGRMTKSFLSSPSSANLASPSSVVRKVEAKYPALLFKQQ 1253
+ G + TP R + L ++ +LA V+ + A+ QQ
Sbjct: 1547 GEEGFMKHNTP------------RQNEHCL---TNFDLAEYRQVLSDL-----AIQIYQQ 1586
Query: 1254 LTAYLEKIYG--IIRDNLTKELTSALALCIQAPRTSKGVLRSGRSFGKDSPMVHWQSIIE 1311
L LE I I+ L E ++ LR S D SII
Sbjct: 1587 LVRVLENILQPMIVSGMLEHETIQGVS------GVKPTGLRKRTSSIADEGTYTLDSIIR 1640
Query: 1312 SLNTLLCTLKENFIPPVLIRKIFSQTFAFINVQLFN-----------SNGEYVKAGLAEL 1360
LN+ + ++ + P LI+++ Q F I N S G ++ +++L
Sbjct: 1641 QLNSFHSVMCQHGMDPELIKQVVKQMFYIIGAVTLNNLLLRKDMCSWSKGMQIRYNVSQL 1700
Query: 1361 ELWCCQAKEEYAGSSWDELKHIRQAVGFLVIHQKYRISYDEIVNDLCPILSVQQLCKICT 1420
E W +G+ + L+ + QA L + +K + I + +C L+ Q+ K+
Sbjct: 1701 EEWLRDKNLMNSGAK-ETLEPLIQAAQLLQVKKKTDEDAEAICS-MCNALTTAQIVKVLN 1758
Query: 1421 LYWDDNYNTRSVSPHVLASMRMDLDSNDAMNDSFLLDDSSSI-----PFSVDDLS 1470
LY N V + ++++ L D + LL D+ I PF+ L+
Sbjct: 1759 LYTPVNEFEERVLVSFIRTIQLRL--RDRKDSPQLLMDAKHIFPVTFPFNPSSLA 1811
Score = 43.1 bits (100), Expect = 0.006
Identities = 44/161 (27%), Positives = 76/161 (46%), Gaps = 29/161 (18%)
Query: 897 QVEDLTLRLQ--LEKRLRVDVE-----EAKAKENERLQSALQKMQLQFKETKVLLEKERE 949
+ EDL LR++ EK+ +D+ + + E E+ + +LQ +L KE + L K +E
Sbjct: 1133 EAEDLPLRMEEPSEKKAPLDMSLFLKLQKRVTELEQEKQSLQD-ELDRKEEQALRAKAKE 1191
Query: 950 ATKKLEARVPVIQEVPAVDHALLEKLSSENEKLKTLVSSLEKKIDETEK----------- 998
E R P+ + ++L SEN+KLK ++ L+K + ET
Sbjct: 1192 -----EERPPIRGAELEYESLKRQELESENKKLKNELNELQKALTETRAPEVTAPGAPAY 1246
Query: 999 --RYEEEAKVSEE---RLKQALDAESKVIQMKTAMQRLEEK 1034
++ VSEE R ++ L S+++ K A+Q E+K
Sbjct: 1247 RVLLDQLTSVSEELEVRKEEVLILRSQLVSQKEAIQPKEDK 1287
>MY5A_HUMAN (Q9Y4I1) Myosin Va (Myosin 5A) (Dilute myosin heavy chain,
non-muscle) (Myosin heavy chain 12) (Myoxin)
Length = 1855
Score = 671 bits (1730), Expect = 0.0
Identities = 418/1093 (38%), Positives = 613/1093 (55%), Gaps = 74/1093 (6%)
Query: 12 VWIEDSDIAWIDGEVVGVNGEEIKVLCT---SGKTVVV----KASKIYHKDTEVPPSGVD 64
VWI D + W E++ KVL GK + K ++ H G +
Sbjct: 13 VWIPDPEEVWKSAELLKDYKPGDKVLLLHLEEGKDLEYHLDPKTKELPHLRNPDILVGEN 72
Query: 65 DMTKLAYLHEPGVLNNLRSRY-DINEIYTYTGNILIAVNPFIKLPHLYDIHMMAQYKGVA 123
D+T L+YLHEP VL+NLR R+ D IYTY G +L+A+NP+ +LP +Y ++ Y G
Sbjct: 73 DLTALSYLHEPAVLHNLRVRFIDSKLIYTYCGIVLVAINPYEQLP-IYGEDIINAYSGQN 131
Query: 124 FGELSPHPFAVADAAYRLMINEGISQSILVSGESGAGKTETTKLLMRYLAYMGGRAAVAE 183
G++ PH FAVA+ AY+ M + +QSI+VSGESGAGKT + K MRY A + G A+ A
Sbjct: 132 MGDMDPHIFAVAEEAYKQMARDERNQSIIVSGESGAGKTVSAKYAMRYFATVSGSASEAN 191
Query: 184 GRTVEQKVLESNPVLEAFGNAKTVRNNNSSRFGKFVEIQFDQKGRISGAAIRTYLLERSR 243
VE+KVL SNP++E+ GNAKT RN+NSSRFGK++EI FD++ RI GA +RTYLLE+SR
Sbjct: 192 ---VEEKVLTSNPIMESIGNAKTTRNDNSSRFGKYIEIGFDKRYRIIGANMRTYLLEKSR 248
Query: 244 VCQLSDPERNYHCFYMLCA-APAEVVKKYKLGHPRTFHYLNQSNCYELEGLDESKEYITI 302
V ++ ERNYH FY LCA A K +LG+ F+Y Q +EG+D++KE
Sbjct: 249 VVFQAEEERNYHIFYQLCASAKLPEFKMLRLGNADNFNYTKQGGSPVIEGVDDAKEMAHT 308
Query: 303 RRAMDVVGISIENQDAIFQVVAAILHLGNIEFVKGDEIDSSMPKDEKSRFHLQTAAELFM 362
R+A ++GIS +Q IF+++A ILHLGN+ F D ++P + L +L
Sbjct: 309 RQACTLLGISESHQMGIFRILAGILHLGNVGFTSRDADSCTIPPKHEP---LCIFCDLMG 365
Query: 363 CDANALEDSLCKRVIVTRDETITKWLDPEAAALSRDALAKIVYTRLFDWLVDTINNSIGQ 422
D + LC R + T ET K + A +RDALAK +Y +LF+W+VD +N ++
Sbjct: 366 VDYEEMCHWLCHRKLATATETYIKPISKLQATNARDALAKHIYAKLFNWIVDNVNQALHS 425
Query: 423 DPESKSLIGVLDIYGFESFKNNSFEQFCINLTNEKLQQHFNQHVFKMEQEEYKKEEIDWS 482
+ S IGVLDIYGFE+F+ NSFEQFCIN NEKLQQ FN HVFK+EQEEY KE+I W+
Sbjct: 426 AVKQHSFIGVLDIYGFETFEINSFEQFCINYANEKLQQQFNMHVFKLEQEEYMKEQIPWT 485
Query: 483 YIEFVDNQDILDLIEKKPGGIISLLDEACMFPRSTHETFSQKLYQTFKDH-KRFSKPKLS 541
I+F DNQ ++LIE K GI+ LLDE C P+ T +T++QKLY T + F KP+LS
Sbjct: 486 LIDFYDNQPCINLIESKL-GILDLLDEECKMPKGTDDTWAQKLYNTHLNKCALFEKPRLS 544
Query: 542 PSDFTICHYAGDVTYQTEYFLDKNKDYVVAEHQSLLYASTCPFVSGLFPPSPEETSKQSK 601
F I H+A V YQ E FL+KNKD V E +L +S + LF + S S
Sbjct: 545 NKAFIIQHFADKVEYQCEGFLEKNKDTVFEEQIKVLKSSKFKMLPELFQDDEKAISPTSA 604
Query: 602 FSS---------------------------IGSRFKQQLQSLLETLSSTEPHYIRCVKPN 634
SS +G +F+ L L+ETL++T PHY+RC+KPN
Sbjct: 605 TSSGRTPLTRTPAKPTKGRPGQMAKEHKKTVGHQFRNSLHLLMETLNATTPHYVRCIKPN 664
Query: 635 NLLKPAIFDNKNVLLQLRCGGVMEAIRISCAGYPTRKAFDEFVDRFGLLAPEVLDGSSEE 694
+ P FD K + QLR GV+E IRIS AG+P+R + EF R+ +L + D S+
Sbjct: 665 DFKFPFTFDEKRAVQQLRACGVLETIRISAAGFPSRWTYQEFFSRYRVLMKQ-KDVLSDR 723
Query: 695 VTACKRILKNVWL--EGYQIGKTKVFLRAGQMAELDTRRSEILGKSASIIQRKVRSYLAR 752
CK +L+ + L + YQ GKTK+F RAGQ+A L+ R++ L + IQ+ +R +L R
Sbjct: 724 KQTCKNVLEKLILDKDKYQFGKTKIFFRAGQVAYLEKLRADKLRAACIRIQKTIRGWLLR 783
Query: 753 QSFILLRVSALQIQAACRGQLARQVFEGMRREASSLLIQRCLRMHIAKKAYKELYASAVS 812
+ ++ +R +A+ +Q RG AR + +RR ++ +IQ+ RM++ ++ YK A+ +
Sbjct: 784 KKYLRMRKAAITMQRYVRGYQARCYAKFLRRTKAATIIQKYWRMYVVRRRYKIRRAATIV 843
Query: 813 IQTGMRVMAAHCELHSRRRTSAAIIIQSHCRKYLALLNFTKLKKAAIATQCAWRGKVARR 872
+Q+ +R A R A+IIQ R +LA ++ + A I QC +R +A+R
Sbjct: 844 LQSYLRGFLARNRYRKILREHKAVIIQKRVRGWLARTHYKRSMHAIIYLQCCFRRMMAKR 903
Query: 873 ELRKLKMAARETG-------ALQDAKNKLEKQVEDLTLRLQLEKRLRVDVEEAKAKENER 925
EL+KLK+ AR +++ +L+++V++ + ++E E E+
Sbjct: 904 ELKKLKIEARSVERYKKLHIGMENKIMQLQRKVDEQNKDYKCLVEKLTNLEGIYNSETEK 963
Query: 926 LQSALQKMQLQFKETKV----LLEKEREATKKLEARVPVIQEVPAV-DHA---------L 971
L+S L+++QL +E KV +L + E K + E + +HA L
Sbjct: 964 LRSDLERLQLSEEEAKVATGRVLSLQEEIAKLRKDLEQTRSEKKCIEEHADRYKQETEQL 1023
Query: 972 LEKLSSENEKLKTLVSSLEKKIDETEKRYEE--EAKVSEERLKQALDAESKVIQMKTAM- 1028
+ L EN LK +L +I + K E E K+ EE + LD + ++ + +
Sbjct: 1024 VSNLKEENTLLKQEKEALNHRIVQQAKEMTETMEKKLVEETKQLELDLNDERLRYQNLLN 1083
Query: 1029 --QRLEEKFADIE 1039
RLEE++ D++
Sbjct: 1084 EFSRLEERYDDLK 1096
Score = 50.1 bits (118), Expect = 5e-05
Identities = 130/636 (20%), Positives = 257/636 (39%), Gaps = 106/636 (16%)
Query: 874 LRKLKMAARETGALQDAKNKLEKQVEDLTLRLQLEKRLRVDVEEAKA----KENERLQSA 929
LR ++ +E +D KN + D T+ L+ ++++ E A+A KE R SA
Sbjct: 1269 LRSQLVSQKEAIQPKDDKNTMT----DSTILLEDVQKMKDKGEIAQAYIGLKETNR-SSA 1323
Query: 930 LQKMQL-QFKETKVLLEKEREATKKLEARVPVIQ-----EVPAVDHALLEKLSSENEKLK 983
L +L + E ++ E ++A + LE+++ + E A+ ++ L EN + +
Sbjct: 1324 LDYHELNEDGELWLVYEGLKQANRLLESQLQSQKRSHENEAEAL-RGEIQSLKEENNRQQ 1382
Query: 984 TLVSSL-----EKKIDETEKRYEEEAKVSEERLK--QALDAESKVIQ-MKTAMQRLEEKF 1035
L++ E +I+ + + E +++ E L + L+ + K ++ +K ++ +K
Sbjct: 1383 QLLAQNLQLPPEARIEASLQH--EITRLTNENLDLMEQLEKQDKTVRKLKKQLKVFAKKI 1440
Query: 1036 ADIEFANHVLQKQSLSINSPVKTAVENLSTPVSEKLENGHHVAEEPYDADTYVTPVKQFV 1095
++E V Q +++S + + ++ P EK G + ++
Sbjct: 1441 GELE----VGQMENISPGQIIDEPIRPVNIPRKEKDFQG----------------MLEYK 1480
Query: 1096 AESDVKLKRSCSERHHGSFDSLVNCVSKNIGFNHGKPIAAFTIYKCLLH--WKSFEAERS 1153
E + KL ++ ++ + + N + A+ ++ C+ H + + + +
Sbjct: 1481 KEDEQKLVKNL----------ILELKPRGVAVNLIPGLPAYILFMCVRHADYLNDDQKVR 1530
Query: 1154 SVFDRLIQMIGSAIEDQ-DDNALMAYWLSNTSALLFLLEQSLKTGTSTNATPNGKPPNPT 1212
S+ I I ++ + DD +++WLSNT L L+Q +G N N
Sbjct: 1531 SLLTSTINSIKKVLKKRGDDFETVSFWLSNTCRFLHCLKQ--YSGEEGFMKHNTSRQNEH 1588
Query: 1213 SLFGRMTKSFLSSPSSANLASPSSVVRKVEAKYPALLFKQQLTAYLEKIYG--IIRDNLT 1270
L ++ +LA V+ + A+ QQL LE I I+ L
Sbjct: 1589 CL------------TNFDLAEYRQVLSDL-----AIQIYQQLVRVLENILQPMIVSGMLE 1631
Query: 1271 KELTSALALCIQAPRTSKGVLRSGRSFGKDSPMVHWQSIIESLNTLLCTLKENFIPPVLI 1330
E ++ LR S D SI+ LN+ + ++ + P LI
Sbjct: 1632 HETIQGVS------GVKPTGLRKRTSSIADEGTYTLDSILRQLNSFHSVMCQHGMDPELI 1685
Query: 1331 RKIFSQTFAFINVQLFN-----------SNGEYVKAGLAELELWCCQAKEEYAGSSWDEL 1379
+++ Q F I N S G ++ +++LE W +G+ + L
Sbjct: 1686 KQVVKQMFYIIGAITLNNLLLRKDMCSWSKGMQIRYNVSQLEEWLRDKNLMNSGAK-ETL 1744
Query: 1380 KHIRQAVGFLVIHQKYRISYDEIVNDLCPILSVQQLCKICTLYWDDNYNTRSVSPHVLAS 1439
+ + QA L + +K + I + +C L+ Q+ K+ LY N VS + +
Sbjct: 1745 EPLIQAAQLLQVKKKTDDDAEAICS-MCNALTTAQIVKVLNLYTPVNEFEERVSVSFIRT 1803
Query: 1440 MRMDLDSNDAMNDSFLLDDSSSI-----PFSVDDLS 1470
++M L D + LL D+ I PF+ L+
Sbjct: 1804 IQMRL--RDRKDSPQLLMDAKHIFPVTFPFNPSSLA 1837
>MY5A_MOUSE (Q99104) Myosin Va (Myosin 5A) (Dilute myosin heavy chain,
non-muscle)
Length = 1853
Score = 669 bits (1727), Expect = 0.0
Identities = 417/1113 (37%), Positives = 621/1113 (55%), Gaps = 88/1113 (7%)
Query: 12 VWIEDSDIAWIDGEVVGVNGEEIKVLCT---SGKTVVV----KASKIYHKDTEVPPSGVD 64
VWI D + W E++ KVL GK + K ++ H G +
Sbjct: 13 VWIPDPEEVWKSAELLKDYKPGDKVLLLHLEEGKDLEYRLDPKTGELPHLRNPDILVGEN 72
Query: 65 DMTKLAYLHEPGVLNNLRSRY-DINEIYTYTGNILIAVNPFIKLPHLYDIHMMAQYKGVA 123
D+T L+YLHEP VL+NLR R+ D IYTY G +L+A+NP+ +LP +Y ++ Y G
Sbjct: 73 DLTALSYLHEPAVLHNLRVRFIDSKLIYTYCGIVLVAINPYEQLP-IYGEDIINAYSGQN 131
Query: 124 FGELSPHPFAVADAAYRLMINEGISQSILVSGESGAGKTETTKLLMRYLAYMGGRAAVAE 183
G++ PH FAVA+ AY+ M + +QSI+VSGESGAGKT + K MRY A + G A+ A
Sbjct: 132 MGDMDPHIFAVAEEAYKQMARDERNQSIIVSGESGAGKTVSAKYAMRYFATVSGSASEAN 191
Query: 184 GRTVEQKVLESNPVLEAFGNAKTVRNNNSSRFGKFVEIQFDQKGRISGAAIRTYLLERSR 243
VE+KVL SNP++E+ GNAKT RN+NSSRFGK++EI FD++ RI GA +RTYLLE+SR
Sbjct: 192 ---VEEKVLASNPIMESIGNAKTTRNDNSSRFGKYIEIGFDKRYRIIGANMRTYLLEKSR 248
Query: 244 VCQLSDPERNYHCFYMLCA-APAEVVKKYKLGHPRTFHYLNQSNCYELEGLDESKEYITI 302
V ++ ERNYH FY LCA A K +LG+ +FHY Q +EG+D++KE
Sbjct: 249 VVFQAEEERNYHIFYQLCASAKLPEFKMLRLGNADSFHYTKQGGSPMIEGVDDAKEMAHT 308
Query: 303 RRAMDVVGISIENQDAIFQVVAAILHLGNIEFVKGDEIDSSMPKDEKSRFHLQTAAELFM 362
R+A ++GIS Q IF+++A ILHLGN+ F D ++P + L +L
Sbjct: 309 RQACTLLGISESYQMGIFRILAGILHLGNVGFASRDSDSCTIPPKHEP---LTIFCDLMG 365
Query: 363 CDANALEDSLCKRVIVTRDETITKWLDPEAAALSRDALAKIVYTRLFDWLVDTINNSIGQ 422
D + LC R + T ET K + A +RDALAK +Y +LF+W+VD +N ++
Sbjct: 366 VDYEEMCHWLCHRKLATATETYIKPISKLQATNARDALAKHIYAKLFNWIVDHVNQALHS 425
Query: 423 DPESKSLIGVLDIYGFESFKNNSFEQFCINLTNEKLQQHFNQHVFKMEQEEYKKEEIDWS 482
+ S IGVLDIYGFE+F+ NSFEQFCIN NEKLQQ FN HVFK+EQEEY KE+I W+
Sbjct: 426 AVKQHSFIGVLDIYGFETFEINSFEQFCINYANEKLQQQFNMHVFKLEQEEYMKEQIPWT 485
Query: 483 YIEFVDNQDILDLIEKKPGGIISLLDEACMFPRSTHETFSQKLYQTFKDH-KRFSKPKLS 541
I+F DNQ ++LIE K GI+ LLDE C P+ T +T++QKLY T + F KP++S
Sbjct: 486 LIDFYDNQPCINLIESKL-GILDLLDEECKMPKGTDDTWAQKLYNTHLNKCALFEKPRMS 544
Query: 542 PSDFTICHYAGDVTYQTEYFLDKNKDYVVAEHQSLLYASTCPFVSGLF--------PPS- 592
F I H+A V YQ E FL+KNKD V E +L +S + LF P S
Sbjct: 545 NKAFIIKHFADKVEYQCEGFLEKNKDTVFEEQIKVLKSSKFKMLPELFQDDEKAISPTSA 604
Query: 593 -------------------PEETSKQSKFSSIGSRFKQQLQSLLETLSSTEPHYIRCVKP 633
P +T+K+ K ++G +F+ L L+ETL++T PHY+RC+KP
Sbjct: 605 TSSGRTPLTRVPVKPTKGRPGQTAKEHK-KTVGHQFRNSLHLLMETLNATTPHYVRCIKP 663
Query: 634 NNLLKPAIFDNKNVLLQLRCGGVMEAIRISCAGYPTRKAFDEFVDRFGLLAPEVLDGSSE 693
N+ P FD K + QLR GV+E IRIS G+P+R + EF R+ +L + D +
Sbjct: 664 NDFKFPFTFDEKRAVQQLRACGVLETIRISARGFPSRWTYQEFFSRYRVLMKQ-KDVLGD 722
Query: 694 EVTACKRILKNVWL--EGYQIGKTKVFLRAGQMAELDTRRSEILGKSASIIQRKVRSYLA 751
CK +L+ + L + YQ GKTK+F RAGQ+A L+ R++ L + IQ+ +R +L
Sbjct: 723 RKQTCKNVLEKLILDKDKYQFGKTKIFFRAGQVAYLEKLRADKLRAACIRIQKTIRGWLL 782
Query: 752 RQSFILLRVSALQIQAACRGQLARQVFEGMRREASSLLIQRCLRMHIAKKAYKELYASAV 811
R+ ++ ++ +A+ +Q RG AR + +RR ++ IQ+ RM++ ++ YK A+ +
Sbjct: 783 RKRYLCMQRAAITVQRYVRGYQARCYAKFLRRTKAATTIQKYWRMYVVRRRYKIRRAATI 842
Query: 812 SIQTGMRVMAAHCELHSRRRTSAAIIIQSHCRKYLALLNFTKLKKAAIATQCAWRGKVAR 871
IQ+ +R R A+IIQ R +LA ++ + KA + QC +R +A+
Sbjct: 843 VIQSYLRGYLTRNRYRKILREYKAVIIQKRVRGWLARTHYKRTMKAIVYLQCCFRRMMAK 902
Query: 872 RELRKLKMAARETG-------ALQDAKNKLEKQVEDLTLRLQLEKRLRVDVEEAKAKENE 924
R+++KLK+ AR +++ +L+++V++ + ++E E E
Sbjct: 903 RDVKKLKIEARSVERYKKLHIGMENKIMQLQRKVDEQNKDYKCLMEKLTNLEGVYNSETE 962
Query: 925 RLQSALQKMQLQFKETKVL-----------------LEKEREATKKLEARVPVIQEVPAV 967
+L++ ++++QL +E KV LE+ R K +E R ++
Sbjct: 963 KLRNDVERLQLSEEEAKVATGRVLSLQEEIAKLRKDLEQTRSEKKSIEERADKYKQ---E 1019
Query: 968 DHALLEKLSSENEKLKTLVSSLEKKIDETEKRYEE--EAKVSEERLKQALDAESKVIQMK 1025
L+ L EN LK +L +I E K E E K+ EE + LD + ++ +
Sbjct: 1020 TDQLVSNLKEENTLLKQEKETLNHRIVEQAKEMTETMERKLVEETKQLELDLNDERLRYQ 1079
Query: 1026 TAM---QRLEEKFADIEFANHVLQKQSLSINSP 1055
+ RLEE++ D++ ++ +L +N P
Sbjct: 1080 NLLNEFSRLEERYDDLK------EEMTLMLNVP 1106
Score = 52.8 bits (125), Expect = 7e-06
Identities = 126/634 (19%), Positives = 244/634 (37%), Gaps = 104/634 (16%)
Query: 874 LRKLKMAARETGALQDAKNKLEKQVEDLTLRLQLEKRLRVDVEEAKA-----KENERLQS 928
LR ++ +E +D KN + D T+ L+ ++++ E A+A + N L+S
Sbjct: 1269 LRSQLVSQKEAIQPKDDKNTMT----DSTILLEDVQKMKDKGEIAQAYIGLKETNRLLES 1324
Query: 929 ALQKMQLQFKETKVLLEKEREATKKLEAR----------VPVIQEVPAVDHALLEKLSSE 978
LQ + + L E ++ K+ R +P + A + +L++E
Sbjct: 1325 QLQSQKRSHENEAEALRGEIQSLKEENNRQQQLLAQNLQLPPEARIEASLQHEITRLTNE 1384
Query: 979 NEKLKTLVSSLEKKIDETE-KRYEEEAKVSEERLKQALDAESKVIQMKTAMQRLEEKFAD 1037
N + L + KK Y+ + E+ KQ + V ++K ++ +K +
Sbjct: 1385 NLYFEELYADDPKKYQSYRISLYKRMIDLMEQLEKQ----DKTVRKLKKQLKVFAKKIGE 1440
Query: 1038 IEFANHVLQKQSLSINSPVKTAVENLSTPVSEKLENGHHVAEEPYDADTYVTPVKQFVAE 1097
+E V Q +++S + + ++ P EK G + ++ E
Sbjct: 1441 LE----VGQMENISPGQIIDEPIRPVNIPRKEKDFQG----------------MLEYKRE 1480
Query: 1098 SDVKLKRSCSERHHGSFDSLVNCVSKNIGFNHGKPIAAFTIYKCLLH--WKSFEAERSSV 1155
+ KL ++ ++ + + N + A+ ++ C+ H + + + + S+
Sbjct: 1481 DEQKLVKNL----------ILELKPRGVAVNLIPGLPAYILFMCVRHADYLNDDQKVRSL 1530
Query: 1156 FDRLIQMIGSAIEDQ-DDNALMAYWLSNTSALLFLLEQSLKTGTSTNATPNGKPPNPTSL 1214
I I ++ + DD +++WLSNT L L+Q +G N N L
Sbjct: 1531 LTSTINSIKKVLKKRGDDFETVSFWLSNTCRFLHCLKQ--YSGEEGFMKHNTSRQNEHCL 1588
Query: 1215 FGRMTKSFLSSPSSANLASPSSVVRKVEAKYPALLFKQQLTAYLEKIYG--IIRDNLTKE 1272
++ +LA V+ + A+ QQL LE I I+ L E
Sbjct: 1589 ------------TNFDLAEYRQVLSDL-----AIQIYQQLVRVLENILQPMIVSGMLEHE 1631
Query: 1273 LTSALALCIQAPRTSKGVLRSGRSFGKDSPMVHWQSIIESLNTLLCTLKENFIPPVLIRK 1332
++ LR S D SI+ LN+ + ++ + P LI++
Sbjct: 1632 TIQGVS------GVKPTGLRKRTSSIADEGTYTLDSILRQLNSFHSVMCQHGMDPELIKQ 1685
Query: 1333 IFSQTFAFINVQLFN-----------SNGEYVKAGLAELELWCCQAKEEYAGSSWDELKH 1381
+ Q F + N S G ++ +++LE W +G+ + L+
Sbjct: 1686 VVKQMFYIVGAITLNNLLLRKDMCSWSKGMQIRYNVSQLEEWLRDKNLMNSGAK-ETLEP 1744
Query: 1382 IRQAVGFLVIHQKYRISYDEIVNDLCPILSVQQLCKICTLYWDDNYNTRSVSPHVLASMR 1441
+ QA L + +K + I + +C L+ Q+ K+ LY N VS + +++
Sbjct: 1745 LIQAAQLLQVKKKTDDDAEAICS-MCNALTTAQIVKVLNLYTPVNEFEERVSVSFIRTIQ 1803
Query: 1442 MDLDSNDAMNDSFLLDDSSSI-----PFSVDDLS 1470
M L D + LL D+ I PF+ L+
Sbjct: 1804 MRL--RDRKDSPQLLMDAKHIFPVTFPFNPSSLA 1835
>MY5A_RAT (Q9QYF3) Myosin Va (Myosin 5A) (Dilute myosin heavy chain,
non-muscle)
Length = 1828
Score = 669 bits (1726), Expect = 0.0
Identities = 419/1113 (37%), Positives = 622/1113 (55%), Gaps = 88/1113 (7%)
Query: 12 VWIEDSDIAWIDGEVVGVNGEEIKVLCT---SGKTVVV----KASKIYHKDTEVPPSGVD 64
VWI D + W E++ KVL GK + K S++ H G +
Sbjct: 13 VWIPDPEEVWKSAELLKDYKPGDKVLLLHLEEGKDLEYRLDPKTSELPHLRNPDILVGEN 72
Query: 65 DMTKLAYLHEPGVLNNLRSRY-DINEIYTYTGNILIAVNPFIKLPHLYDIHMMAQYKGVA 123
D+T L+YLHEP VL+NLR R+ D IYTY G +L+A+NP+ +LP +Y ++ Y G
Sbjct: 73 DLTALSYLHEPAVLHNLRVRFIDSKLIYTYCGIVLVAINPYEQLP-IYGEDIINAYSGQN 131
Query: 124 FGELSPHPFAVADAAYRLMINEGISQSILVSGESGAGKTETTKLLMRYLAYMGGRAAVAE 183
G++ PH FAVA+ AY+ M + +QSI+VSGESGAGKT + K MRY A + G A+ A
Sbjct: 132 MGDMDPHIFAVAEEAYKQMARDERNQSIIVSGESGAGKTVSAKYAMRYFATVSGSASEAN 191
Query: 184 GRTVEQKVLESNPVLEAFGNAKTVRNNNSSRFGKFVEIQFDQKGRISGAAIRTYLLERSR 243
VE+KVL SNP++E+ GNAKT RN+NSSRFGK++EI FD++ RI GA +RTYLLE+SR
Sbjct: 192 ---VEEKVLASNPIMESIGNAKTTRNDNSSRFGKYIEIGFDKRYRIIGANMRTYLLEKSR 248
Query: 244 VCQLSDPERNYHCFYMLCA-APAEVVKKYKLGHPRTFHYLNQSNCYELEGLDESKEYITI 302
V ++ ERNYH FY LCA A K +LG+ +FHY Q +EG+D++KE
Sbjct: 249 VVFQAEEERNYHIFYQLCASAKLPEFKMLRLGNADSFHYTKQGGSPMIEGVDDAKEMAHT 308
Query: 303 RRAMDVVGISIENQDAIFQVVAAILHLGNIEFVKGDEIDSSMPKDEKSRFHLQTAAELFM 362
R+A ++GIS Q IF+++A ILHLGN+ F D ++P + L +L
Sbjct: 309 RQACTLLGISESYQMGIFRILAGILHLGNVGFASRDSDSCTIPPKHEP---LIIFCDLMG 365
Query: 363 CDANALEDSLCKRVIVTRDETITKWLDPEAAALSRDALAKIVYTRLFDWLVDTINNSIGQ 422
D + LC R + T ET K + A +RDALAK +Y +LF+W+V +N ++
Sbjct: 366 VDYEEMCHWLCHRKLATATETYIKPISKLQATNARDALAKHIYAKLFNWIVGHVNQALHS 425
Query: 423 DPESKSLIGVLDIYGFESFKNNSFEQFCINLTNEKLQQHFNQHVFKMEQEEYKKEEIDWS 482
+ S IGVLDIYGFE+F+ NSFEQFCIN NEKLQQ FN HVFK+EQEEY KE+I W+
Sbjct: 426 AVKQHSFIGVLDIYGFETFEINSFEQFCINYANEKLQQQFNMHVFKLEQEEYMKEQIPWT 485
Query: 483 YIEFVDNQDILDLIEKKPGGIISLLDEACMFPRSTHETFSQKLYQTFKDH-KRFSKPKLS 541
I+F DNQ ++LIE K GI+ LLDE C P+ T +T++QKLY T + F KP++S
Sbjct: 486 LIDFYDNQPCINLIESKL-GILDLLDEECKMPKGTDDTWAQKLYNTHLNKCALFEKPRMS 544
Query: 542 PSDFTICHYAGDVTYQTEYFLDKNKDYVVAEHQSLLYASTCPFVSGLF--------PPS- 592
F I H+A V YQ E FL+KNKD V E +L +S + LF P S
Sbjct: 545 NKAFIIKHFADKVEYQCEGFLEKNKDTVFEEQIKVLKSSKFKMLPELFQDDEKAISPTSA 604
Query: 593 -------------------PEETSKQSKFSSIGSRFKQQLQSLLETLSSTEPHYIRCVKP 633
P +T+K+ K ++G +F+ L L+ETL++T PHY+RC+KP
Sbjct: 605 TSSGRTPLTRVPVKPTKGRPGQTAKEHK-KTVGLQFRNSLHLLMETLNATTPHYVRCIKP 663
Query: 634 NNLLKPAIFDNKNVLLQLRCGGVMEAIRISCAGYPTRKAFDEFVDRFGLLAPEVLDGSSE 693
N+ P FD K + QLR GV+E IRIS AG+P+R + EF R+ +L + D +
Sbjct: 664 NDFKFPFTFDEKRAVQQLRACGVLETIRISAAGFPSRWTYQEFFSRYRVLMKQ-KDVLGD 722
Query: 694 EVTACKRILKNVWL--EGYQIGKTKVFLRAGQMAELDTRRSEILGKSASIIQRKVRSYLA 751
C+ +L+ + L + YQ GKTK+F RAGQ+A L+ R++ L + IQ+ +R +L
Sbjct: 723 RKQTCQNVLEKLILDKDKYQFGKTKIFFRAGQVAYLEKLRADKLRAACIRIQKTIRGWLL 782
Query: 752 RQSFILLRVSALQIQAACRGQLARQVFEGMRREASSLLIQRCLRMHIAKKAYKELYASAV 811
R+ ++ ++ +A+ +Q RG AR + +RR ++ IQ+ RM++ ++ YK A+ +
Sbjct: 783 RKRYLCMQRAAITVQRYVRGYQARCYAKFLRRTKAATTIQKYWRMYVVRRKYKIRRAATI 842
Query: 812 SIQTGMRVMAAHCELHSRRRTSAAIIIQSHCRKYLALLNFTKLKKAAIATQCAWRGKVAR 871
+Q+ +R A R A+IIQ R +LA ++ + KA I QC +R +A+
Sbjct: 843 VLQSYLRGYLARNRYRKILREHKAVIIQKRVRGWLARTHYKRTMKAIIYLQCCFRRMMAK 902
Query: 872 RELRKLKMAARETG-------ALQDAKNKLEKQVEDLTLRLQLEKRLRVDVEEAKAKENE 924
REL+KLK+ AR +++ +L+++V++ + ++E E E
Sbjct: 903 RELKKLKIEARSVERYKKLHIGMENKIMQLQRKVDEQNKDYKCLMEKLTNLEGVYNSETE 962
Query: 925 RLQSALQKMQLQFKETKVL-----------------LEKEREATKKLEARVPVIQEVPAV 967
+L++ ++++QL +E KV LE+ R K +E R ++
Sbjct: 963 KLRNDVERLQLSEEEAKVATGRVLSLQEEIAKLRKDLEQTRSEKKSIEERADKYKQ---E 1019
Query: 968 DHALLEKLSSENEKLKTLVSSLEKKIDETEKRYEE--EAKVSEERLKQALDAESKVIQMK 1025
L+ L EN LK +L + E K E E K+ EE + LD + ++ +
Sbjct: 1020 TEQLVSNLKEENTLLKQEKETLNHLMVEQAKEMTETMERKLVEETKQLELDLNDERLRYQ 1079
Query: 1026 TAM---QRLEEKFADIEFANHVLQKQSLSINSP 1055
+ RLEE++ D++ ++ +L +N P
Sbjct: 1080 NLLNEFSRLEERYDDLK------EEMTLMLNVP 1106
Score = 50.1 bits (118), Expect = 5e-05
Identities = 123/653 (18%), Positives = 249/653 (37%), Gaps = 70/653 (10%)
Query: 847 ALLNFTKLKKAAIATQCAWRGKVARRELRKLKMAARETGALQ------DAKNKLEKQVED 900
A L + LK+ + ++ K + EL +L+ A E A + A L +Q+
Sbjct: 1199 AELGYESLKRQELESE----NKKLKNELNELRKALSEKSAPEVNAPGAPAYRVLMEQLTA 1254
Query: 901 LTLRLQLEKRLRVDVEEAKAKENERLQSALQKMQLQFKETKVLLEKEREATKKLEARVPV 960
++ L + K + + + E +Q K + ++ +LLE ++ K E
Sbjct: 1255 VSEELDVRKEEVLILRSQLVSQKEAIQPKDDKNTMT--DSTILLEDVQKMKDKGEIAQAY 1312
Query: 961 IQEVPAVDHALLEKLSSENEKLKTLVSSLEKKIDETEKRYEEEAKVSEERLKQALDAESK 1020
I + + L +L S+ + +L +I ++ + ++ + L+ +A +
Sbjct: 1313 IG-LKETNRLLESQLQSQKRSHENEAEALRGEIQSLKEENNRQQQLLAQNLQLPPEARIE 1371
Query: 1021 VIQMKTAMQRLEEKFADIEFANHVLQKQSLSINSPVKTAVENLSTPVSEKLEN--GHHVA 1078
++ + RL + D+ K + +K + + ++EN +
Sbjct: 1372 A-SLQHEITRLTNENLDLMEQLEKQDKTVRKLKKQLKVFAKKIGELEVGQMENISPGQII 1430
Query: 1079 EEPYDADTYVTPVKQFVAESDVKLKRSCSERHHGSFDSLVNCVSKNIGFNHGKPIAAFTI 1138
+EP K F + ++ KR ++ + ++ + + N + A+ +
Sbjct: 1431 DEPIRPVNIPRKGKDF--QGMLEYKREDEQKLVKNL--ILELKPRGVAVNLISGLPAYIL 1486
Query: 1139 YKCLLHWKSFEAERS--SVFDRLIQMIGSAIEDQ-DDNALMAYWLSNTSALLFLLEQSLK 1195
+ C+ H + ++ S+ I I ++ + DD +++WLSNT L L+Q
Sbjct: 1487 FMCVRHADYLDDDQKVRSLLTSTINSIKKVLKKRGDDFETVSFWLSNTCRFLHCLKQ--Y 1544
Query: 1196 TGTSTNATPNGKPPNPTSLFGRMTKSFLSSPSSANLASPSSVVRKVEAKYPALLFKQQLT 1255
+G N N L ++ +LA V+ + A+ QQL
Sbjct: 1545 SGEEGFMKHNTSRQNEHCL------------TNFDLAEYRQVLSDL-----AIQIYQQLV 1587
Query: 1256 AYLEKIYG--IIRDNLTKELTSALALCIQAPRTSKGVLRSGRSFGKDSPMVHWQSIIESL 1313
LE I I+ L E ++ LR S D SI+ L
Sbjct: 1588 RVLENILQPMIVSGMLEHETIQGVS------GVKPTGLRKRTSSIADEGTYTLDSILRQL 1641
Query: 1314 NTLLCTLKENFIPPVLIRKIFSQTFAFINVQLFN-----------SNGEYVKAGLAELEL 1362
N+ + ++ + P LI+++ Q F + N S G ++ +++LE
Sbjct: 1642 NSFHSVMCQHGMDPELIKQVVKQMFYIVGAITLNNLLLRKDMCSWSKGMQIRYNVSQLEE 1701
Query: 1363 WCCQAKEEYAGSSWDELKHIRQAVGFLVIHQKYRISYDEIVNDLCPILSVQQLCKICTLY 1422
W +G+ + L+ + QA L + +K + I + +C L+ Q+ K+ LY
Sbjct: 1702 WLRDKNLMNSGAK-ETLEPLIQAAQLLQVKKKTDDDAEAICS-MCNALTTAQIVKVLNLY 1759
Query: 1423 WDDNYNTRSVSPHVLASMRMDLDSNDAMNDSFLLDDSSSI-----PFSVDDLS 1470
N VS + ++++ L D + LL D+ I PF+ L+
Sbjct: 1760 TPVNEFEERVSVSFIRTIQVRL--RDRKDSPQLLMDAKHIFPVTFPFNPSSLA 1810
>MY5B_HUMAN (Q9ULV0) Myosin Vb (Myosin 5B)
Length = 1849
Score = 659 bits (1699), Expect = 0.0
Identities = 406/1086 (37%), Positives = 616/1086 (56%), Gaps = 80/1086 (7%)
Query: 10 THVWIEDSDIAWIDGEVVGVNGEEIKVLCTSGKTVVVKASKIYHKDTEVP----PS---G 62
T VWI D D W E+ E K L + + I + ++P P G
Sbjct: 11 TRVWIPDPDEVWRSAELTKDYKEGDKSLQLRLEDETILEYPIDVQRNQLPFLRNPDILVG 70
Query: 63 VDDMTKLAYLHEPGVLNNLRSRY-DINEIYTYTGNILIAVNPFIKLPHLYDIHMMAQYKG 121
+D+T L+YLHEP VL+NL+ R+ + N IYTY G +L+A+NP+ +LP +Y ++ Y G
Sbjct: 71 ENDLTALSYLHEPAVLHNLKVRFLESNHIYTYCGIVLVAINPYEQLP-IYGQDVIYAYSG 129
Query: 122 VAFGELSPHPFAVADAAYRLMINEGISQSILVSGESGAGKTETTKLLMRYLAYMGGRAAV 181
G++ PH FAVA+ AY+ M + +QSI+VSGESGAGKT + K MRY A +GG A+
Sbjct: 130 QNMGDMDPHIFAVAEEAYKQMARDEKNQSIIVSGESGAGKTVSAKYAMRYFATVGGSASE 189
Query: 182 AEGRTVEQKVLESNPVLEAFGNAKTVRNNNSSRFGKFVEIQFDQKGRISGAAIRTYLLER 241
+E+KVL S+P++EA GNAKT RN+NSSRFGK+++I FD++ I GA +RTYLLE+
Sbjct: 190 TN---IEEKVLASSPIMEAIGNAKTTRNDNSSRFGKYIQIGFDKRYHIIGANMRTYLLEK 246
Query: 242 SRVCQLSDPERNYHCFYMLCAAPA-EVVKKYKLGHPRTFHYLNQSNCYELEGLDESKEYI 300
SRV +D ERNYH FY LCAA K+ L F Y +Q +EG+D+++++
Sbjct: 247 SRVVFQADDERNYHIFYQLCAAAGLPEFKELALTSAEDFFYTSQGGDTSIEGVDDAEDFE 306
Query: 301 TIRRAMDVVGISIENQDAIFQVVAAILHLGNIEFVKGDEIDSSM--PKDEKSRFHLQTAA 358
R+A ++G+ +Q +IF+++A+ILHLG++ + DS P+D +L
Sbjct: 307 KTRQAFTLLGVKESHQMSIFKIIASILHLGSVAIQAERDGDSCSISPQD----VYLSNFC 362
Query: 359 ELFMCDANALEDSLCKRVIVTRDETITKWLDPEAAALSRDALAKIVYTRLFDWLVDTINN 418
L + + +E LC R +VT ET K + + +R+ALAK +Y +LF W+V+ IN
Sbjct: 363 RLLGVEHSQMEHWLCHRKLVTTSETYVKTMSLQQVINARNALAKHIYAQLFGWIVEHINK 422
Query: 419 SIGQDPESKSLIGVLDIYGFESFKNNSFEQFCINLTNEKLQQHFNQHVFKMEQEEYKKEE 478
++ + S IGVLDIYGFE+F+ NSFEQFCIN NEKLQQ FN HVFK+EQEEY KE+
Sbjct: 423 ALHTSLKQHSFIGVLDIYGFETFEVNSFEQFCINYANEKLQQQFNSHVFKLEQEEYMKEQ 482
Query: 479 IDWSYIEFVDNQDILDLIEKKPGGIISLLDEACMFPRSTHETFSQKLYQTFKDHKRFSKP 538
I W+ I+F DNQ +DLIE K GI+ LLDE C P+ T + ++QKLY + F KP
Sbjct: 483 IPWTLIDFYDNQPCIDLIEAKL-GILDLLDEECKVPKGTDQNWAQKLYDRHSSSQHFQKP 541
Query: 539 KLSPSDFTICHYAGDVTYQTEYFLDKNKDYVVAEHQSLLYASTCPFVSGLF----PPSPE 594
++S + F I H+A V Y ++ FL+KN+D V E ++L AS P V+ LF P P
Sbjct: 542 RMSNTAFIIVHFADKVEYLSDGFLEKNRDTVYEEQINILKASKFPLVADLFHDDKDPVPA 601
Query: 595 ET---SKQSKFS-----------------SIGSRFKQQLQSLLETLSSTEPHYIRCVKPN 634
T SK S ++G +F+ L L+ETL++T PHY+RC+KPN
Sbjct: 602 TTPGKGSSSKISVRSARPPMKVSNKEHKKTVGHQFRTSLHLLMETLNATTPHYVRCIKPN 661
Query: 635 NLLKPAIFDNKNVLLQLRCGGVMEAIRISCAGYPTRKAFDEFVDRFGLLAPEVLDGSSEE 694
+ P FD K + QLR GV+E IRIS AGYP+R A+ +F +R+ +L + ++++
Sbjct: 662 DEKLPFHFDPKRAVQQLRACGVLETIRISAAGYPSRWAYHDFFNRYRVLVKKRELANTDK 721
Query: 695 VTACKRILKNVWL--EGYQIGKTKVFLRAGQMAELDTRRSEILGKSASIIQRKVRSYLAR 752
C+ +L+N+ + +Q G+TK+F RAGQ+A L+ R++ + +IQ+ VR +L +
Sbjct: 722 KAICRSVLENLIKDPDKFQFGRTKIFFRAGQVAYLEKLRADKFRTATIMIQKTVRGWLQK 781
Query: 753 QSFILLRVSALQIQAACRGQLARQVFEGMRREASSLLIQRCLRMHIAKKAYKELYASAVS 812
+ L+ + L +Q CRG LAR++ E +RR +++++Q+ RM A++AY+ + +AV
Sbjct: 782 VKYHRLKGATLTLQRYCRGHLARRLAEHLRRIRAAVVLQKHYRMQRARQAYQRVRRAAVV 841
Query: 813 IQTGMRVMAAHCELHSRRRTSAAIIIQSHCRKYLALLNFTKLKKAAIATQCAWRGKVARR 872
IQ R M A IQ H R ++A +F +L+ AAI QCA+R ARR
Sbjct: 842 IQAFTRAMFVRRTYRQVLMEHKATTIQKHVRGWMARRHFQRLRDAAIVIQCAFRMLKARR 901
Query: 873 ELRKLKMAARETGALQDAKNKLEKQVEDLTLRLQLEKRLRVDVEEAKAKENERLQSALQK 932
EL+ L++ AR L+ +E +V +QL++++ +E K
Sbjct: 902 ELKALRIEARSAEHLKRLNVGMENKV------VQLQRKIDEQNKEFKTLSE--------- 946
Query: 933 MQLQFKETKVLLEKEREATKKLEARVPVIQEVPAVDHALLEKLSSENEKLKTLVSSLEKK 992
QL + +E ER L+ + Q+ P D +L +L E E L+T L++
Sbjct: 947 -QLSVTTSTYTMEVER-----LKKELVHYQQSPGEDTSL--RLQEEVESLRT---ELQRA 995
Query: 993 IDETEKRYEEEAKVSEERLKQALDAESKVIQMKTAMQRL--------EEKFADIEFANHV 1044
E + + ++ +E K+ D E + +K ++L +++FA ++
Sbjct: 996 HSERKILEDAHSREKDELRKRVADLEQENALLKDEKEQLNNQILCQSKDEFAQNSVKENL 1055
Query: 1045 LQKQSL 1050
L K+ L
Sbjct: 1056 LMKKEL 1061
Score = 57.0 bits (136), Expect = 4e-07
Identities = 124/596 (20%), Positives = 209/596 (34%), Gaps = 116/596 (19%)
Query: 883 ETGALQDAKNKLEKQVEDLTLRLQLEKRLRVDVEEAKAKENERLQSALQKMQLQFKETKV 942
E G L A L++ L +LQ + + E + E L+ + K Q F +T +
Sbjct: 1326 EDGELGLAYQGLKQVARLLEAQLQAQSLEHEEEVEHLKAQLEALKEEMDKQQQTFCQTLL 1385
Query: 943 LLEKEREATKKLEARVPVIQEVPAVDHALLEKLSSENEKLKTLVSSLEKKIDETEKRYEE 1002
L + + + V QE+ +L++EN LK LV LEK
Sbjct: 1386 L-------SPEAQVEFGVQQEI--------SRLTNENLDLKELVEKLEK----------- 1419
Query: 1003 EAKVSEERLKQALDAESKVIQMKTAMQRLEEKFADIEFANHVLQKQSLSINSPVKTAVEN 1062
+E +LK+ L K Q A Q L A E H L +Q V+
Sbjct: 1420 ----NERKLKKQLKIYMKKAQDLEAAQAL----AQSERKRHELNRQ---------VTVQR 1462
Query: 1063 LSTPVSEKLENGHHVAEEPYDADTYVTPVKQFVAESDVKLKRSCSERHHGSFDSLVNCVS 1122
LE +H +E VT +K + V
Sbjct: 1463 KEKDFQGMLE--YHKEDEALLIRNLVTDLKPQMLSGTVPC-------------------- 1500
Query: 1123 KNIGFNHGKPIAAFTIYKCLLH--WKSFEAERSSVFDRLIQMIGSAIEDQ-DDNALMAYW 1179
+ A+ +Y C+ H + + + + S+ I I ++ DD + ++W
Sbjct: 1501 ----------LPAYILYMCIRHADYTNDDLKVHSLLTSTINGIKKVLKKHNDDFEMTSFW 1550
Query: 1180 LSNTSALLFLLEQSLKTGTSTNATPNGKPPNPTSLFGRMTKSFLSSPSSANLASPSSVVR 1239
LSNT LL L+Q +G T N N L + S ++ +++
Sbjct: 1551 LSNTCRLLHCLKQY--SGDEGFMTQNTAKQNEHCLKNFDLTEYRQVLSDLSIQIYQQLIK 1608
Query: 1240 KVEAKYPALLFKQQLTAYLEKIYGIIRDNLTKELTSALALCIQAPRTSKGVLRSGRSFGK 1299
E ++ L E I G+ T G + S
Sbjct: 1609 IAEGVLQPMIVSAMLEN--ESIQGLSGVKPT------------------GYRKRSSSMAD 1648
Query: 1300 DSPMVHWQSIIESLNTLLCTLKENFIPPVLIRKIFSQTFAFINVQLFN-----------S 1348
++II +N + + + P +I ++F Q F IN N S
Sbjct: 1649 GDNSYCLEAIIRQMNAFHTVMCDQGLDPEIILQVFKQLFYMINAVTLNNLLLRKDVCSWS 1708
Query: 1349 NGEYVKAGLAELELWCCQAKEEYAGSSWDELKHIRQAVGFLVIHQKYRISYDEIVNDLCP 1408
G ++ +++LE W + + + + ++ + QA L + +K + + I + LC
Sbjct: 1709 TGMQLRYNISQLEEWL-RGRNLHQSGAVQTMEPLIQAAQLLQLKKKTQEDAEAICS-LCT 1766
Query: 1409 ILSVQQLCKICTLYWDDNYNTRSVSPHVLASMRMDL-DSNDAMNDSFLLDDSSSIP 1463
LS QQ+ KI LY N V+ + +++ L + ND LLD P
Sbjct: 1767 SLSTQQIVKILNLYTPLNEFEERVTVAFIRTIQAQLQERNDP--QQLLLDAKHMFP 1820
Score = 39.3 bits (90), Expect = 0.082
Identities = 37/126 (29%), Positives = 63/126 (49%), Gaps = 29/126 (23%)
Query: 879 MAARETGALQDAKNK-----LEKQVEDLTLRLQLEKRLRVDVEEAKAKENERLQSALQKM 933
++ E G +DA + LEK D+T+ L+L+KR+R L+ +K+
Sbjct: 1117 ISTSEIGDTEDALQQVEEIGLEKAAMDMTVFLKLQKRVR------------ELEQERKKL 1164
Query: 934 QLQFKETKVLLEKEREATKKLEARVPV--IQEVPAVDHAL----LEKLSSENEKLKTLVS 987
Q+Q L ++E++ +KK++A P I P D A ++L SEN+KLK ++
Sbjct: 1165 QVQ------LEKREQQDSKKVQAEPPQTDIDLDPNADLAYNSLKRQELESENKKLKNDLN 1218
Query: 988 SLEKKI 993
L K +
Sbjct: 1219 ELRKAV 1224
>MY5B_RAT (P70569) Myosin Vb (Myosin 5B) (Myosin heavy chain myr 6)
Length = 1846
Score = 656 bits (1693), Expect = 0.0
Identities = 407/1088 (37%), Positives = 623/1088 (56%), Gaps = 70/1088 (6%)
Query: 10 THVWIEDSDIAWIDGEVVG--VNGEEIKVLCTSGKTVVVKASKIYHKDTEVP----PS-- 61
T VWI D D W E+ +G+E L T++ + ++ +VP P
Sbjct: 11 TRVWIPDPDEVWRSAELTKDYKDGDESLQLRLEDDTILDYPIDV--QNNQVPFLRNPDIL 68
Query: 62 -GVDDMTKLAYLHEPGVLNNLRSRY-DINEIYTYTGNILIAVNPFIKLPHLYDIHMMAQY 119
G +D+T L++LHEP VL+NL+ R+ + N IYTY G +L+A+NP+ +LP +Y ++ Y
Sbjct: 69 VGENDLTALSHLHEPAVLHNLKVRFLESNHIYTYCGIVLVAINPYEQLP-IYGQDVIYAY 127
Query: 120 KGVAFGELSPHPFAVADAAYRLMINEGISQSILVSGESGAGKTETTKLLMRYLAYMGGRA 179
G G++ PH FAVA+ AY+ M + +QSI+VSGESGAGKT + K MRY A +GG A
Sbjct: 128 SGQNMGDMDPHIFAVAEEAYKQMARDEKNQSIIVSGESGAGKTVSAKYAMRYFATVGGSA 187
Query: 180 AVAEGRTVEQKVLESNPVLEAFGNAKTVRNNNSSRFGKFVEIQFDQKGRISGAAIRTYLL 239
+ +E+KVL S+P++EA GNAKT RN+NSSRFGK++EI FD+K I GA +RTYLL
Sbjct: 188 S---DTNIEEKVLASSPIMEAIGNAKTTRNDNSSRFGKYIEIGFDKKYHIIGANMRTYLL 244
Query: 240 ERSRVCQLSDPERNYHCFYMLCAAPA-EVVKKYKLGHPRTFHYLNQSNCYELEGLDESKE 298
E+SRV +D ERNYH FY LCAA + K+ L F Y +EG+D++++
Sbjct: 245 EKSRVVFQADDERNYHIFYQLCAAASLPEFKELALTCAEDFFYTAHGGNTTIEGVDDAED 304
Query: 299 YITIRRAMDVVGISIENQDAIFQVVAAILHLGNIEFVKGDEIDSSM--PKDEKSRFHLQT 356
+ R+A+ ++G+ +Q +IF+++A+ILHLG++E + DS P+DE HL
Sbjct: 305 FEKTRQALTLLGVRESHQISIFKIIASILHLGSVEIQAERDGDSCSISPQDE----HLSN 360
Query: 357 AAELFMCDANALEDSLCKRVIVTRDETITKWLDPEAAALSRDALAKIVYTRLFDWLVDTI 416
L + + +E LC R +VT ET K + + +R+ALAK +Y +LF W+V+ I
Sbjct: 361 FCRLLGIEHSQMEHWLCHRKLVTTSETYVKTMSLQQVVNARNALAKHIYAQLFSWIVEHI 420
Query: 417 NNSIGQDPESKSLIGVLDIYGFESFKNNSFEQFCINLTNEKLQQHFNQHVFKMEQEEYKK 476
N ++ + S IGVLDIYGFE+F+ NSFEQFCIN NEKLQQ FN HVFK+EQEEY K
Sbjct: 421 NKALQTSLKQHSFIGVLDIYGFETFEINSFEQFCINYANEKLQQQFNSHVFKLEQEEYMK 480
Query: 477 EEIDWSYIEFVDNQDILDLIEKKPGGIISLLDEACMFPRSTHETFSQKLYQTFKDHKRFS 536
E+I W+ I+F DNQ +DLIE K GI+ LLDE C P+ T + ++QKLY+ + + F
Sbjct: 481 EQIPWTLIDFYDNQPCIDLIEAKL-GILDLLDEECKVPKGTDQNWAQKLYERHSNSQHFQ 539
Query: 537 KPKLSPSDFTICHYAGDVTYQTEYFLDKNKDYVVAEHQSLLYASTCPFVSGLFPPS---- 592
KP++S + F + H+A V Y ++ FL+KN+D V E ++L AS P V+ LF
Sbjct: 540 KPRMSNTAFIVIHFADKVEYLSDGFLEKNRDTVYEEQINILKASKFPLVADLFRDDEDSV 599
Query: 593 PEETSKQSKFS---------------------SIGSRFKQQLQSLLETLSSTEPHYIRCV 631
P + +S+ S S+G +F+ L L+ETL++T PHY+RC+
Sbjct: 600 PATNTAKSRSSSKINVRSSRPLMKAPNKEHKKSVGYQFRTSLNLLMETLNATTPHYVRCI 659
Query: 632 KPNNLLKPAIFDNKNVLLQLRCGGVMEAIRISCAGYPTRKAFDEFVDRFG-LLAPEVLDG 690
KPN+ P FD K + QLR GV+E IRIS AGYP+R + +F +R+ L+ L
Sbjct: 660 KPNDEKLPFHFDPKRAVQQLRACGVLETIRISAAGYPSRWTYHDFFNRYRVLMKKRELAN 719
Query: 691 SSEEVTACKRILKNVWL--EGYQIGKTKVFLRAGQMAELDTRRSEILGKSASIIQRKVRS 748
++++ CK +L+++ + +Q G+TK+F RAGQ+A L+ R++ ++ +IQ+ VR
Sbjct: 720 TTDKKNICKSVLESLIKDPDKFQFGRTKIFFRAGQVAYLEKLRADKFREATIMIQKTVRG 779
Query: 749 YLARQSFILLRVSALQIQAACRGQLARQVFEGMRREASSLLIQRCLRMHIAKKAYKELYA 808
+L R + LR + L +Q CRG LAR++ E +RR ++++ Q+ RM A++AY +
Sbjct: 780 WLQRVKYRRLRAATLTLQRFCRGYLARRLTEHLRRTRAAIVFQKQYRMLKARRAYCRVRR 839
Query: 809 SAVSIQTGMRVMAAHCELHSRRRTSAAIIIQSHCRKYLALLNFTKLKKAAIATQCAWRGK 868
+AV IQ+ R +L A IIQ + R ++A +F + + AAI QCA+R
Sbjct: 840 AAVIIQSYTRGHVCTQKLPPVLTEHKATIIQKYARGWMARRHFQRQRDAAIVIQCAFRRL 899
Query: 869 VARRELRKLKMAARETGALQ----DAKNK---LEKQVEDLTLRLQLEKRLRVDVEEAKAK 921
AR+ L+ LK+ AR L+ +NK L+++++D + V A
Sbjct: 900 KARQALKALKIEARSAEHLKRLNVGMENKVVQLQRKIDDQNKEFKTLSEQLSAVTSTHAM 959
Query: 922 ENERLQSALQK-MQLQFKETKVLLEKE----REATKKLEARVPVIQEVPAVDHALLEK-- 974
E E+L+ L + Q Q + + L++E R +K + V+++ ++ L K
Sbjct: 960 EVEKLKKELARYQQNQEADPSLQLQEEVQSLRTELQKAHSERRVLEDAHNRENGELRKRV 1019
Query: 975 --LSSENEKLKTLVSSLEKKIDETEKRYEEEAKVSEERL--KQALDAESKVIQMKTAMQR 1030
L EN LK L +I K ++ V E L K+ + S+ + +
Sbjct: 1020 ADLEHENALLKDEKEHLNHQILRQSKAESSQSSVEENLLIKKELEEERSRYQNLVKEYSQ 1079
Query: 1031 LEEKFADI 1038
LE+++ ++
Sbjct: 1080 LEQRYENL 1087
Score = 54.3 bits (129), Expect = 2e-06
Identities = 124/598 (20%), Positives = 221/598 (36%), Gaps = 120/598 (20%)
Query: 883 ETGALQDAKNKLEKQVEDLTLRLQLEK-RLRVDVEEAKAKENERLQSALQKMQLQFKETK 941
E G L A L++ L +LQ + + +VE KA+ E ++ + K Q F +T
Sbjct: 1323 EDGELGLAYQGLKQVARLLEAQLQAQNLKHEEEVEHLKAQV-EAMKEEMDKQQQTFCQTL 1381
Query: 942 VLLEKEREATKKLEARVPVIQEVPAVDHALLEKLSSENEKLKTLVSSLEKKIDETEKRYE 1001
+L + + + V QE+ +L++EN K LV LEK
Sbjct: 1382 LL-------SPEAQVEFGVQQEI--------SRLTNENLDFKELVEKLEK---------- 1416
Query: 1002 EEAKVSEERLKQALDAESKVIQMKTAMQRLEEKFADIEFANHVLQKQSLSINSPVKTAVE 1061
+E++LK+ L K +Q A Q L A + +H L +Q V+
Sbjct: 1417 -----NEKKLKKQLKIYMKKVQDLEAAQAL----AQSDRRHHELTRQ---------VTVQ 1458
Query: 1062 NLSTPVSEKLENGHHVAEEPYDADTYVTPVKQFVAESDVKLKRSCSERHHGSFDSLVNCV 1121
LE +H +E VT +K + V
Sbjct: 1459 RKEKDFQGMLE--YHKEDEALLIRNLVTDLKPQMLSGTVPC------------------- 1497
Query: 1122 SKNIGFNHGKPIAAFTIYKCLLH--WKSFEAERSSVFDRLIQMIGSAIEDQ-DDNALMAY 1178
+ A+ +Y C+ H + + + + S+ I I ++ +D + ++
Sbjct: 1498 -----------LPAYILYMCIRHADYTNDDLKVHSLLSSTINGIKKVLKKHNEDFEMTSF 1546
Query: 1179 WLSNTSALLFLLEQSLKTGTSTNATPNGKPPNPTSLFGRMTKSFLSSPSSANLASPSSVV 1238
WLSNT LL L+Q +G T N N L + S ++ ++
Sbjct: 1547 WLSNTCRLLHCLKQY--SGDEGFMTQNTAKQNEHCLKNFDLTEYRQVLSDLSIQIYQQLI 1604
Query: 1239 RKVEAKYPALLFKQQLTAYLEKIYGI--IRDNLTKELTSALALCIQAPRTSKGVLRSGRS 1296
+ E ++ L E I G+ +R ++ +S++
Sbjct: 1605 KIAEGLLQPMIVSAMLEN--ESIQGLSGVRPTGYRKRSSSMV------------------ 1644
Query: 1297 FGKDSPMVHWQSIIESLNTLLCTLKENFIPPVLIRKIFSQTFAFINVQLFN--------- 1347
G++S + ++II +N L + + P +I ++F Q F IN N
Sbjct: 1645 DGENSYCL--EAIIRQMNFFHTVLCDQGLDPEIILQVFKQLFYMINAVTLNNLLLRKDAC 1702
Query: 1348 --SNGEYVKAGLAELELWCCQAKEEYAGSSWDELKHIRQAVGFLVIHQKYRISYDEIVND 1405
S G ++ +++LE W + K + ++ + QA L + +K + + I +
Sbjct: 1703 SWSTGMQLRYNISQLEEWL-RGKNLQQSGAVQTMEPLIQAAQLLQLKKKTQEDAEAICS- 1760
Query: 1406 LCPILSVQQLCKICTLYWDDNYNTRSVSPHVLASMRMDLDSNDAMNDSFLLDDSSSIP 1463
LC LS QQ+ KI LY N V+ + +++ L + LLD P
Sbjct: 1761 LCTSLSTQQIVKILNLYTPLNGFEERVTVSFIRTIQAQLQER-SDPQQLLLDSKHMFP 1817
Score = 37.4 bits (85), Expect = 0.31
Identities = 43/172 (25%), Positives = 84/172 (48%), Gaps = 39/172 (22%)
Query: 879 MAARETGALQDAKNK-----LEKQVEDLTLRLQLEKRLRVDVEEAKAKENERLQSALQKM 933
++ E G +DA + +EK D+T+ L+L+KR+R L+ +K+
Sbjct: 1115 ISTSEIGDTEDALQQVEEIGIEKAAMDMTVFLKLQKRVR------------ELEQERKKL 1162
Query: 934 QLQFKETKVLLEKEREATKKLEAR-----VPVIQEVPAVDHAL-LEKLSSENEKLKTLVS 987
Q+Q LEKE++ +KK++ + V Q+ ++L ++L SEN+KLK
Sbjct: 1163 QVQ-------LEKEQQDSKKVQVEQQNNGLDVDQDADIAYNSLKRQELESENKKLK---- 1211
Query: 988 SLEKKIDETEKRYEEEAKVSEERLKQALDAESKVI-QMKTAMQRLEEKFADI 1038
++E K ++A + + + D+ S ++ Q+K A + LE + ++
Sbjct: 1212 ---NDLNERWKAVADQA-MQDNSTHSSPDSYSLLLNQLKLANEELEVRKEEV 1259
>MY2A_SACCA (Q875X3) Myosin-2A (Class V unconventional myosin MYO2A)
(Type V myosin heavy chain MYO2A) (Myosin V MYO2A)
Length = 1567
Score = 655 bits (1691), Expect = 0.0
Identities = 506/1557 (32%), Positives = 765/1557 (48%), Gaps = 154/1557 (9%)
Query: 8 VGTHVWIEDSDIAWIDGEVVGVNGEE----IKVLCTSGKTVVVKASKIYH-KDTEVPP-- 60
VGT W + WI EV + ++ +++ + V V+ + + KD +P
Sbjct: 5 VGTRCWYPSKEQGWIGAEVTKNDLKDGTYFMELTLEDNEVVNVETKDLTNEKDPSLPLLR 64
Query: 61 -----SGVDDMTKLAYLHEPGVLNNLRSRYDINEIYTYTGNILIAVNPFIKLPHLYDIHM 115
+D+T L+YL+EP VL+ ++ RY IYTY+G +LIA NPF ++ LY M
Sbjct: 65 NPPILESTEDLTTLSYLNEPAVLHAIKQRYSQLNIYTYSGIVLIATNPFDRMDQLYSQDM 124
Query: 116 MAQYKGVAFGELSPHPFAVADAAYRLMINEGISQSILVSGESGAGKTETTKLLMRYLAY- 174
+ Y G GE+ PH FA+A+ AYRLM N+ +Q+I+VSGESGAGKT + K +MRY A
Sbjct: 125 IQAYSGKRRGEIEPHLFAIAEEAYRLMKNDKQNQTIVVSGESGAGKTVSAKYIMRYFASC 184
Query: 175 -------MGGRAAVAEGRTVEQKVLESNPVLEAFGNAKTVRNNNSSRFGKFVEIQFDQKG 227
MG AE E+++L +NP++EAFGNAKT RN+NSSRFGK++EI FD++
Sbjct: 185 DEENSSNMGNLQHTAEMSETEERILATNPIMEAFGNAKTTRNDNSSRFGKYLEILFDKET 244
Query: 228 RISGAAIRTYLLERSRVCQLSDPERNYHCFYMLCAA-PAEVVKKYKLGHPRTFHYLNQSN 286
I GA +RTYLLERSR+ ERNYH FY + A P +V ++ L + Y+NQ
Sbjct: 245 AIIGAKMRTYLLERSRLVYQPKTERNYHIFYQILAGLPEDVKQELHLTKADDYFYMNQGG 304
Query: 287 CYELEGLDESKEYITIRRAMDVVGISIENQDAIFQVVAAILHLGNIEFVKGDEIDSSMPK 346
E+ G+D+ EY +A+ +VG++ E Q IF+++AA+LH+GNIE +K DSS+
Sbjct: 305 EPEIAGIDDVSEYGITIKALTLVGVAPETQQHIFKILAALLHIGNIE-IKKTRNDSSLSS 363
Query: 347 DEKSRFHLQTAAELFMCDANALEDSLCKRVIVTRDETITKWLDPEAAALSRDALAKIVYT 406
DE + L+ A EL D + + K+ IVTR E I L+ A ++RD++AK +Y+
Sbjct: 364 DEPN---LKIACELLGVDPSNFAKWITKKQIVTRSEKIVSNLNYSQALVARDSVAKFIYS 420
Query: 407 RLFDWLVDTINNSIGQDP---ESKSLIGVLDIYGFESFKNNSFEQFCINLTNEKLQQHFN 463
LFDWLV IN + + S IGVLDIYGFE F+ NSFEQFCIN NEKLQQ FN
Sbjct: 421 ALFDWLVTNINTVLCNPAVLDQIHSFIGVLDIYGFEHFEKNSFEQFCINYANEKLQQEFN 480
Query: 464 QHVFKMEQEEYKKEEIDWSYIEFVDNQDILDLIEKKPGGIISLLDEACMFPRSTHETFSQ 523
QHVFK+EQEEY KEEI+WS+IEF DNQ +DLIE K GI+SLLDE P + E+++Q
Sbjct: 481 QHVFKLEQEEYIKEEIEWSFIEFNDNQPCIDLIENKL-GILSLLDEESRLPAGSDESWTQ 539
Query: 524 KLYQTF---KDHKRFSKPKLSPSDFTICHYAGDVTYQTEYFLDKNKDYVVAEHQSLLYAS 580
KLYQT +K FSKP+ + F + HYA DV Y E F++KN+D V H +L A+
Sbjct: 540 KLYQTLDKPPTNKVFSKPRFGQTKFVVSHYALDVAYDVEGFIEKNRDTVSDGHLEVLKAT 599
Query: 581 TCPFVSGLFPPSPE-----ETSKQSKFS-------------------SIGSRFKQQLQSL 616
T +S + E E +K++ S ++GS FK L L
Sbjct: 600 TNDTLSTILESVEESARKVEEAKKNAASQDQKQLKKPTPIRQVQRKPTLGSMFKLSLIEL 659
Query: 617 LETLSSTEPHYIRCVKPNNLLKPAIFDNKNVLLQLRCGGVMEAIRISCAGYPTRKAFDEF 676
++T++ST HYIRC+KPN + FDN VL QLR GV+E IRISCAG+P+R F+EF
Sbjct: 660 MQTINSTNVHYIRCIKPNGEKEAWKFDNLMVLSQLRACGVLETIRISCAGFPSRWTFNEF 719
Query: 677 VDRFGLLAPEV--------LDGSSEEV-TACKRILKNVW--LEGYQIGKTKVFLRAGQMA 725
+ R+ +L P V D + ++V CK+IL E YQIG TK+F +AG +A
Sbjct: 720 ILRYYILIPPVEWAPIFQKNDLTEQDVINLCKKILAATVQDKEKYQIGNTKIFFKAGMLA 779
Query: 726 ELDTRRSEILGKSASIIQRKVRSYLARQSFILLRVSALQIQAACRGQLARQVFEGMRREA 785
+ RS + + +IQ+ +RS R+ ++L++ S + A +G + RQ E +
Sbjct: 780 YFEKLRSTKMNSAIVLIQKHIRSKYYRKQYMLMKASLSLLGAYSKGTVIRQRVEYELEQH 839
Query: 786 SSLLIQRCLRMHIAKKAYKELYASAVSIQTGMRVMAAHCELHSRRRTSAAIIIQSHCRKY 845
++ LIQ R + + + +S V +Q+ +R E+ S+ ++AAI IQS R +
Sbjct: 840 AATLIQTMYRGYSKRSYISGVISSIVKLQSRIREELEQREMQSKYESNAAISIQSRIRAF 899
Query: 846 LALLNFTKLKKAAIATQCAWRGKVARRELRKLKMAARETGALQDAKNKLEKQVEDLTLRL 905
+ + ++ I Q R ++A+R+ +KLK A+ L++ KLE +V LT L
Sbjct: 900 VPRKAYESKRRDTIVVQSLIRRRIAQRDFKKLKADAKSVHHLKEVSYKLENKVIQLTQNL 959
Query: 906 QLEKRLRVDVEEAKAKENERLQSALQKMQLQFKETKVLLEKEREATKKLEARVPVIQEVP 965
AK KEN +L L+++Q T L+ + EA K + Q+
Sbjct: 960 -----------AAKVKENRQLSKRLEELQATM-VTVSELQDQLEAQKMENQKALADQK-- 1005
Query: 966 AVDHALLEKLSSENEKLKTL--VSSLEKKIDETEKRYEEEAKVSEERLKQALDAESKVIQ 1023
D +L+ S +++ +K V S++ ++ +Y E S+ +L + ++ + +
Sbjct: 1006 --DGFVLDSKSLKDQLIKANKDVESVKFELATLTAKYTEMEAESKNQLDELERTKTLLTE 1063
Query: 1024 MKTAMQRLEEKFADIEFANHVLQKQSLSINSPVKTAVENL--STPVSE-KLENGHHVAEE 1080
KT L +++I+ L SI T N+ TP E ++ +GH A E
Sbjct: 1064 SKTQNSDL---YSEIKSLKEELAHLQTSIALGTVTTNTNIVPHTPSRENRMPSGHMRAAE 1120
Query: 1081 PYDADTYVTPVKQFVAESDVKLKRSCSERHHGSFDSLVNCVSKNIGFNHGKPIAAFTIYK 1140
+ + + A V + + + ++L + G + I +
Sbjct: 1121 ENISPNQLKSIPSDTAADHVSVNGYGMDDDIINTNTLTQINEELYRLLEGTDVLNNEITE 1180
Query: 1141 CLLHWKSFE----------AERSSVFDRLIQMIGSAIEDQDDNALMAYW-LSNTSALLFL 1189
LL K F+ + R V+ I +I L W T
Sbjct: 1181 GLL--KGFQVPDAGVAIQLSRRDVVYPARILII----------VLSEMWRFGLTKQSESF 1228
Query: 1190 LEQSLKTGTSTNATPNGKPPNPTSLFG----RMTKSFLSSPSSANLASPSSVVRKVEAKY 1245
L Q L T T G P+ F R SF+ + L S + +Y
Sbjct: 1229 LAQVLTTIQKVVTTLKGIDLIPSGAFWLANVRELYSFVVFAQHSILTEESFKKGMNDEEY 1288
Query: 1246 PALL-----FKQQLTAYLEKIYGI----IRDNLTKELTSALALCIQAP----RTSKGVLR 1292
+ K+ + IY I ++ +L K+ +A+ + P S G L
Sbjct: 1289 NEYVSLVTELKEDFESLSYNIYNIWLKKLQKDLQKKAINAVVVSESLPGFNASESNGFLN 1348
Query: 1293 SGRSFGKDSPMVHWQSIIESLNTLLCTLKENFIPPVLIRKIFSQTFAFINVQLFN----- 1347
+ G++ M I+ N + +K I + R + +++ FN
Sbjct: 1349 KIFNSGEEYTM---DDILTFFNNIFWCMKSFHIENEVFRTVIITLLNYVDTICFNDLIMK 1405
Query: 1348 ------SNGEYVKAGLAELELWCCQAKEEYAGSSWDELKHIRQAVGFLVIHQKYRISYDE 1401
G + + LE WC K L+H+ Q L + +KY I +
Sbjct: 1406 RNFLSWKRGLQLNYNVTRLEEWC---KTHGLPDGAQYLQHLIQTAKLLQL-RKYTIEDID 1461
Query: 1402 IVNDLCPILSVQQLCKICTLYWDDNYNTRSVSPHVLASMRMDL---DSNDAMNDSFL 1455
+V +C LS QL K+ + Y +Y S P + D+ +S A ND FL
Sbjct: 1462 MVRGICSSLSPAQLQKLISQYHVADY--ESPIPQDILKYVADIVKKESTSAHNDIFL 1516
>MYS2_SACKL (Q875Q8) Myosin-2 (Class V unconventional myosin MYO2)
(Type V myosin heavy chain MYO2) (Myosin V MYO2)
Length = 1554
Score = 650 bits (1678), Expect = 0.0
Identities = 408/1090 (37%), Positives = 611/1090 (55%), Gaps = 74/1090 (6%)
Query: 8 VGTHVWIEDSDIAWIDGEVVG----VNGEEIKVLCTSGKTVVVKASKIYH-KDTEVPP-- 60
VGT W D WI GE+ N ++++ + V +++ + KD +P
Sbjct: 5 VGTRCWYPDKQQGWIGGEITKHTNLSNKHQLELTLEDNQIVEIESETLDETKDDRLPLLR 64
Query: 61 -----SGVDDMTKLAYLHEPGVLNNLRSRYDINEIYTYTGNILIAVNPFIKLPHLYDIHM 115
+D+T L+YL+EP VL+ +++RY IYTY+G +LIA NPF ++ LY M
Sbjct: 65 NPPILEATEDLTSLSYLNEPAVLHAIKARYAQLNIYTYSGIVLIATNPFDRVEQLYSQDM 124
Query: 116 MAQYKGVAFGELSPHPFAVADAAYRLMINEGISQSILVSGESGAGKTETTKLLMRYLAYM 175
+ Y G GEL PH FA+A+ AYRLM N+ +Q+I+VSGESGAGKT + K +MRY A +
Sbjct: 125 IQAYAGKRRGELEPHLFAIAEEAYRLMKNDKQNQTIVVSGESGAGKTVSAKYIMRYFASV 184
Query: 176 GGRAAV-----AEGRTVEQKVLESNPVLEAFGNAKTVRNNNSSRFGKFVEIQFDQKGRIS 230
E E+K+L +NP++EAFGNAKT RN+NSSRFGK++EI FD++ I
Sbjct: 185 EQNNEENAHHNLEMSETEKKILATNPIMEAFGNAKTTRNDNSSRFGKYLEILFDKEISII 244
Query: 231 GAAIRTYLLERSRVCQLSDPERNYHCFYMLCAAPAEVVK-KYKLGHPRTFHYLNQSNCYE 289
GA IRTYLLERSR+ ERNYH FY L A K + KL +HY+NQ +
Sbjct: 245 GARIRTYLLERSRLVFQPKSERNYHIFYQLLAGLTNEEKSQLKLTGVEDYHYMNQGGEAQ 304
Query: 290 LEGLDESKEYITIRRAMDVVGISIENQDAIFQVVAAILHLGNIEFVKGDEIDSSMPKDEK 349
++G+D+++EY T A+ +VGIS + Q +F+++AA+LH+GN+E +K D+S+ DE
Sbjct: 305 IKGIDDAEEYQTTVEALSLVGISKDTQYQLFKILAALLHIGNVE-IKKTRNDASLSSDEP 363
Query: 350 SRFHLQTAAELFMCDANALEDSLCKRVIVTRDETITKWLDPEAAALSRDALAKIVYTRLF 409
+ L A EL D+ + K+ I TR E I L+ A ++RD++AK +Y+ LF
Sbjct: 364 N---LAIACELLGIDSFNFAKWITKKQINTRSEKIVSNLNYNQALVARDSVAKFIYSALF 420
Query: 410 DWLVDTINNSIGQDP---ESKSLIGVLDIYGFESFKNNSFEQFCINLTNEKLQQHFNQHV 466
+WLVD IN + E S IGVLDIYGFE F+ NSFEQFCIN NEKLQQ FNQHV
Sbjct: 421 EWLVDNINTVLCNPEVASEINSFIGVLDIYGFEHFEKNSFEQFCINYANEKLQQEFNQHV 480
Query: 467 FKMEQEEYKKEEIDWSYIEFVDNQDILDLIEKKPGGIISLLDEACMFPRSTHETFSQKLY 526
FK+EQEEY KEEI+WS+IEF DNQ +DLIE K GI+SLLDE P + ET++QKLY
Sbjct: 481 FKLEQEEYVKEEIEWSFIEFNDNQPCIDLIENKL-GILSLLDEESRLPAGSDETWTQKLY 539
Query: 527 QTF---KDHKRFSKPKLSPSDFTICHYAGDVTYQTEYFLDKNKDYVVAEHQSLLYASTCP 583
QT + FSKP+ + F + HYA DV+Y E F++KN+D V H +L AST
Sbjct: 540 QTLDKPPTNTVFSKPRFGQTKFVVSHYALDVSYDVEGFIEKNRDTVSDGHLEVLKASTNE 599
Query: 584 FVSGLFPPSPEETSK----------------QSKFSSIGSRFKQQLQSLLETLSSTEPHY 627
+ + + +K ++ ++GS FKQ L L+ T++ST HY
Sbjct: 600 TLLSILETLDKHAAKLAEKEQVNKKPGPARMVNRKPTLGSIFKQSLIELMGTINSTNVHY 659
Query: 628 IRCVKPNNLLKPAIFDNKNVLLQLRCGGVMEAIRISCAGYPTRKAFDEFVDRFGLLAPE- 686
IRC+KPN + + +FDN VL QLR GV+E IRISCAG+P+R ++EFV R+ +L P
Sbjct: 660 IRCIKPNEVKEAWVFDNLMVLSQLRACGVLETIRISCAGFPSRWTYNEFVLRYHILIPSE 719
Query: 687 ------VLDGSSEEV-TACKRILKNVW--LEGYQIGKTKVFLRAGQMAELDTRRSEILGK 737
D + E++ C+ IL + + YQ+G TK+F +AG +A L+ RS+ L
Sbjct: 720 HWSKMFSSDTTEEDIRDLCRTILGAIVEDKQKYQLGNTKIFFKAGMLAYLEKLRSDRLHN 779
Query: 738 SASIIQRKVRSYLARQSFILLRVSALQIQAACRGQLARQVFEGMRREASSLLIQRCLRMH 797
S+ +IQ+KV++ R+ ++ + S + G L RQ + + +++LIQ +R
Sbjct: 780 SSVLIQKKVKAVYYRKKYLAIISSIRNFHSRSEGFLTRQRVDLEFKTQAAILIQSMVRST 839
Query: 798 IAKKAYKELYASAVSIQTGMRVMAAHCELHSRRRTSAAIIIQSHCRKYLALLNFTKLKKA 857
+ L ++ +Q+ +R A EL RR+ AA+ IQ R + +F +++
Sbjct: 840 STRNKTISLLSAITRLQSLVRKQLAQKELLQRRQRDAAVSIQKKIRAFEPRQSFNTTRRS 899
Query: 858 AIATQCAWRGKVARRELRKLKMAARETGALQDAKNKLEKQVEDLTLRLQLEKRLRVDVEE 917
+ Q R K A+++L+ LK A+ L++ KLE +V LT L
Sbjct: 900 TVVVQSLVRKKFAQKKLKDLKTEAKSVNHLKEVSYKLENKVIQLTESL-----------A 948
Query: 918 AKAKENERLQSALQKMQLQFKET---KVLLEKEREATKKLEARVPVIQEVPAVDHALLEK 974
K KEN+ + + +Q++Q E+ K LL +++ K+ + +V + + EK
Sbjct: 949 EKVKENKGMTARIQELQQSLNESANIKELLNSQKDEHSKVLQQQKDAHDVQF--NEVQEK 1006
Query: 975 L---SSENEKLKTLVSSLEKKIDETEKRYEEEAKVSEERLKQALDAESKVIQMKTAMQRL 1031
L E E+ K + L K DE + + + + K + +++ +K ++ L
Sbjct: 1007 LVNAKKEVEEAKEEIEQLIAKQDELKAEVRTKIEELNKAKKTFTEFQTQNSDLKNEVKSL 1066
Query: 1032 EEKFADIEFA 1041
+++ A ++ A
Sbjct: 1067 KDEIARLQAA 1076
>MYS2_YEAST (P19524) Myosin-2 (Class V unconventional myosin MYO2)
(Type V myosin heavy chain MYO2) (Myosin V MYO2) (Cell
divison control protein 66)
Length = 1574
Score = 650 bits (1676), Expect = 0.0
Identities = 484/1571 (30%), Positives = 775/1571 (48%), Gaps = 170/1571 (10%)
Query: 8 VGTHVWIEDSDIAWIDGEVVGVNGEEIKV---LCTSGKTVVVKASKIYHKDTEV------ 58
VGT W ++ WI EV+ + K L +V +K + D +
Sbjct: 5 VGTRCWYPHKELGWIGAEVIKNEFNDGKYHLELQLEDDEIVSVDTKDLNNDKDQSLPLLR 64
Query: 59 -PP--SGVDDMTKLAYLHEPGVLNNLRSRYDINEIYTYTGNILIAVNPFIKLPHLYDIHM 115
PP +D+T L+YL+EP VL+ ++ RY IYTY+G +LIA NPF ++ LY M
Sbjct: 65 NPPILEATEDLTSLSYLNEPAVLHAIKQRYSQLNIYTYSGIVLIATNPFDRVDQLYTQDM 124
Query: 116 MAQYKGVAFGELSPHPFAVADAAYRLMINEGISQSILVSGESGAGKTETTKLLMRYLAYM 175
+ Y G GEL PH FA+A+ AYRLM N+ +Q+I+VSGESGAGKT + K +MRY A +
Sbjct: 125 IQAYAGKRRGELEPHLFAIAEEAYRLMKNDKQNQTIVVSGESGAGKTVSAKYIMRYFASV 184
Query: 176 GGRAAVA-----EGRTVEQKVLESNPVLEAFGNAKTVRNNNSSRFGKFVEIQFDQKGRIS 230
+ E EQK+L +NP++EAFGNAKT RN+NSSRFGK++EI FD+ I
Sbjct: 185 EEENSATVQHQVEMSETEQKILATNPIMEAFGNAKTTRNDNSSRFGKYLEILFDKDTSII 244
Query: 231 GAAIRTYLLERSRVCQLSDPERNYHCFYMLCAA-PAEVVKKYKLGHPRTFHYLNQSNCYE 289
GA IRTYLLERSR+ ERNYH FY L A PA+ ++ L + Y+NQ +
Sbjct: 245 GARIRTYLLERSRLVYQPPIERNYHIFYQLMAGLPAQTKEELHLTDASDYFYMNQGGDTK 304
Query: 290 LEGLDESKEYITIRRAMDVVGISIENQDAIFQVVAAILHLGNIEFVKGDEIDSSMPKDEK 349
+ G+D++KEY A+ +VGI+ E Q IF+++AA+LH+GNIE +K D+S+ DE
Sbjct: 305 INGIDDAKEYKITVDALTLVGITKETQHQIFKILAALLHIGNIE-IKKTRNDASLSADEP 363
Query: 350 SRFHLQTAAELFMCDANALEDSLCKRVIVTRDETITKWLDPEAAALSRDALAKIVYTRLF 409
+ L+ A EL DA + K+ I+TR E I L+ A +++D++AK +Y+ LF
Sbjct: 364 N---LKLACELLGIDAYNFAKWVTKKQIITRSEKIVSNLNYSQALVAKDSVAKFIYSALF 420
Query: 410 DWLVDTINNSI---GQDPESKSLIGVLDIYGFESFKNNSFEQFCINLTNEKLQQHFNQHV 466
DWLV+ IN + + + S IGVLDIYGFE F+ NSFEQFCIN NEKLQQ FNQHV
Sbjct: 421 DWLVENINTVLCNPAVNDQISSFIGVLDIYGFEHFEKNSFEQFCINYANEKLQQEFNQHV 480
Query: 467 FKMEQEEYKKEEIDWSYIEFVDNQDILDLIEKKPGGIISLLDEACMFPRSTHETFSQKLY 526
FK+EQEEY KEEI+WS+IEF DNQ +DLIE K GI+SLLDE P + E+++QKLY
Sbjct: 481 FKLEQEEYVKEEIEWSFIEFNDNQPCIDLIENKL-GILSLLDEESRLPAGSDESWTQKLY 539
Query: 527 QTF---KDHKRFSKPKLSPSDFTICHYAGDVTYQTEYFLDKNKDYVVAEHQSLLYASTCP 583
QT +K FSKP+ + F + HYA DV Y E F++KN+D V H +L AST
Sbjct: 540 QTLDKSPTNKVFSKPRFGQTKFIVSHYALDVAYDVEGFIEKNRDTVSDGHLEVLKASTNE 599
Query: 584 FV------------------------SGLFPPSPEETSKQSKFSSIGSRFKQQLQSLLET 619
+ +G P P T + ++GS FKQ L L+ T
Sbjct: 600 TLINILEGLEKAAKKLEEAKKLELEQAGSKKPGPIRTVNRK--PTLGSMFKQSLIELMNT 657
Query: 620 LSSTEPHYIRCVKPNNLLKPAIFDNKNVLLQLRCGGVMEAIRISCAGYPTRKAFDEFVDR 679
++ST HYIRC+KPN + FDN VL QLR GV+E IRISCAG+P+R F+EFV R
Sbjct: 658 INSTNVHYIRCIKPNADKEAWQFDNLMVLSQLRACGVLETIRISCAGFPSRWTFEEFVLR 717
Query: 680 FGLLAP--------EVLDGSSEEVTACKRILKNVWLEG---YQIGKTKVFLRAGQMAELD 728
+ +L P + + + E++ + +++ + ++ YQIG TK+F +AG +A L+
Sbjct: 718 YYILIPHEQWDLIFKKKETTEEDIISVVKMILDATVKDKSKYQIGNTKIFFKAGMLAYLE 777
Query: 729 TRRSEILGKSASIIQRKVRSYLARQSFILLRVSALQIQAACRGQLARQVFEGMRREASSL 788
RS + S +IQ+K+R+ R+ ++ + + +Q +G + RQ + +
Sbjct: 778 KLRSNKMHNSIVMIQKKIRAKYYRKQYLQISQAIKYLQNNIKGFIIRQRVNDEMKVNCAT 837
Query: 789 LIQRCLRMHIAKKAYKELYASAVSIQTGMRVMAAHCELHSRRRTSAAIIIQSHCRKYLAL 848
L+Q R H + + + ++Q +R +L +AA+ IQS R +
Sbjct: 838 LLQAAYRGHSIRANVFSVLRTITNLQKKIRKELKQRQLKQEHEYNAAVTIQSKVRTFEPR 897
Query: 849 LNFTKLKKAAIATQCAWRGKVARRELRKLKMAARETGALQDAKNKLEKQVEDLTLRLQLE 908
F + KK + Q R + A+R+L++LK A+ L++ KLE +V +LT L
Sbjct: 898 SRFLRTKKDTVVVQSLIRRRAAQRKLKQLKADAKSVNHLKEVSYKLENKVIELTQNL--- 954
Query: 909 KRLRVDVEEAKAKENERLQSALQKMQLQFKET------------KVLLEKEREATKKLEA 956
+K KEN+ + ++++Q+Q +E+ + L++ + + +K +E
Sbjct: 955 --------ASKVKENKEMTERIKELQVQVEESAKLQETLENMKKEHLIDIDNQKSKDMEL 1006
Query: 957 RVPVIQEVPAVDHAL------LEKLSSENEKLKTLVSSLEKKIDETEKRYEEEAKVSEER 1010
+ + + + + L LE + ++++LK +++++T+K E ++ +
Sbjct: 1007 QKTIENNLQSTEQTLKDAQLELEDMVKQHDELKEESKKQLEELEQTKKTLVEYQTLNGDL 1066
Query: 1011 LKQALDAESKVIQMKTAMQ--------RLEEKFADI------EFANHVLQKQSLSINSPV 1056
+ + ++ +++TAM + D+ F N +L+ L SP
Sbjct: 1067 QNEVKSLKEEIARLQTAMSLGTVTTSVLPQTPLKDVMGGGASNFNNMMLENSDL---SPN 1123
Query: 1057 KTAVENLSTPVSEKLENGHHVAEEPYDAD-----TYVTPVKQFVAESDVKLKRSCSERHH 1111
+++ STP S +H+ D + T + + E L + +E
Sbjct: 1124 DLNLKSRSTPSS----GNNHIDSLSVDRENGVNATQINEELYRLLEDTEILNQEITEGLL 1179
Query: 1112 GSFDSLVNCVSKNIGFNHGKPIAAFTIYKCLLHWK-SFEAERSSVFDRLIQMIGSAIEDQ 1170
F+ V+ + A I W+ + S +++ I +
Sbjct: 1180 KGFEVPDAGVAIQLSKRDVVYPARILIIVLSEMWRFGLTKQSESFLAQVLTTIQKVVTQL 1239
Query: 1171 DDNALM---AYWLSNTSALLFLLEQSLKTGTSTNATPNGKPPNPTSLFGRMTKSFLSSPS 1227
N L+ +WL+N L + +L + + NG + K ++
Sbjct: 1240 KGNDLIPSGVFWLANVRELYSFVVFALNSILTEETFKNG-------MTDEEYKEYV---- 1288
Query: 1228 SANLASPSSVVRKVEAKYPALLFKQQLTAYLEKIYGIIRDNLTKELTSALALCIQAPRTS 1287
S+V +++ + AL + +L+K ++ L K+ +A+ + P S
Sbjct: 1289 --------SLVTELKDDFEALSY-NIYNIWLKK----LQKQLQKKAINAVVISESLPGFS 1335
Query: 1288 KGVLRSG--RSFGKDSPMVHWQSIIESLNTLLCTLKENFIPPVLIRKIFSQTFAFINVQL 1345
G SG ++ I+ N++ +K I + + + +++
Sbjct: 1336 AGE-TSGFLNKIFANTEEYTMDDILTFFNSIYWCMKSFHIENEVFHAVVTTLLNYVDAIC 1394
Query: 1346 FN-----------SNGEYVKAGLAELELWCCQAKEEYAGSSWDELKHIRQAVGFLVIHQK 1394
FN G + + LE WC K + L+H+ Q L + +K
Sbjct: 1395 FNELIMKRNFLSWKRGLQLNYNVTRLEEWC---KTHGLTDGTECLQHLIQTAKLLQV-RK 1450
Query: 1395 YRISYDEIVNDLCPILSVQQLCKICTLYWDDNYNT---RSVSPHVLASMRMDLDSNDAMN 1451
Y I +I+ +C L+ QL K+ + Y +Y + + + +V ++ + + + N
Sbjct: 1451 YTIEDIDILRGICYSLTPAQLQKLISQYQVADYESPIPQEILRYVADIVKKEAALSSSGN 1510
Query: 1452 DSFLLDDSSSI 1462
DS + SSSI
Sbjct: 1511 DSKGHEHSSSI 1521
>MYS2_SACBA (Q876G9) Myosin-2 (Class V unconventional myosin MYO2)
(Type V myosin heavy chain MYO2) (Myosin V MYO2)
Length = 1568
Score = 641 bits (1654), Expect = 0.0
Identities = 487/1563 (31%), Positives = 766/1563 (48%), Gaps = 160/1563 (10%)
Query: 8 VGTHVWIEDSDIAWIDGEVVGVNGEEIKV---LCTSGKTVVVKASKIYHKDTEV------ 58
VGT W ++ WI EV+ ++ K L VV ++ + D
Sbjct: 5 VGTRCWYPHKELGWIGAEVIKNEVKDGKYHLELSLEDDEVVSVDTEDLNDDKNQSLPLLR 64
Query: 59 -PP--SGVDDMTKLAYLHEPGVLNNLRSRYDINEIYTYTGNILIAVNPFIKLPHLYDIHM 115
PP +D+T L+YL+EP VL+ ++ RY IYTY+G +LIA NPF ++ LY M
Sbjct: 65 NPPILEATEDLTSLSYLNEPAVLHAIKQRYSQLNIYTYSGIVLIATNPFDRVDQLYTQDM 124
Query: 116 MAQYKGVAFGELSPHPFAVADAAYRLMINEGISQSILVSGESGAGKTETTKLLMRYLAYM 175
+ Y G GEL PH FA+A+ AYRLM N+ +Q+I+VSGESGAGKT + K +MRY A +
Sbjct: 125 IQAYAGKRRGELEPHLFAIAEEAYRLMKNDKQNQTIVVSGESGAGKTVSAKYIMRYFASV 184
Query: 176 GGRAAVA-----EGRTVEQKVLESNPVLEAFGNAKTVRNNNSSRFGKFVEIQFDQKGRIS 230
+ E EQ++L +NP++EAFGNAKT RN+NSSRFGK++EI FD++ I
Sbjct: 185 EEENSTTIQHQVEMSETEQRILATNPIMEAFGNAKTTRNDNSSRFGKYLEILFDKETSII 244
Query: 231 GAAIRTYLLERSRVCQLSDPERNYHCFYMLCAA-PAEVVKKYKLGHPRTFHYLNQSNCYE 289
GA IRTYLLERSR+ ERNYH FY L A PA+ ++ L + Y+NQ +
Sbjct: 245 GARIRTYLLERSRLVYQPPIERNYHIFYQLMAGLPAQTKEELHLTDASDYFYMNQGGDTK 304
Query: 290 LEGLDESKEYITIRRAMDVVGISIENQDAIFQVVAAILHLGNIEFVKGDEIDSSMPKDEK 349
+ G+D+++EY T A+ +VGI+ Q IF+++AA+LH+GNIE +K D+S+ DE
Sbjct: 305 IAGIDDAEEYQTTVDALTLVGITTATQHQIFKILAALLHIGNIE-IKKTRNDASLSADEP 363
Query: 350 SRFHLQTAAELFMCDANALEDSLCKRVIVTRDETITKWLDPEAAALSRDALAKIVYTRLF 409
S L+ A EL D+ + K+ IVTR E I L+ A +++D++AK +Y+ LF
Sbjct: 364 S---LKLACELLGIDSYNFAKWITKKQIVTRSEKIVSNLNFNQAMVAKDSVAKFIYSALF 420
Query: 410 DWLVDTINNSIGQ---DPESKSLIGVLDIYGFESFKNNSFEQFCINLTNEKLQQHFNQHV 466
DWLV+ IN + D + S IGVLDIYGFE F+ NSFEQFCIN NEKLQQ FNQHV
Sbjct: 421 DWLVENINTVLCNPDVDDQINSFIGVLDIYGFEHFEKNSFEQFCINYANEKLQQEFNQHV 480
Query: 467 FKMEQEEYKKEEIDWSYIEFVDNQDILDLIEKKPGGIISLLDEACMFPRSTHETFSQKLY 526
FK+EQEEY EEI+WS+IEF DNQ +DLIE K GI+SLLDE P + E+++QKLY
Sbjct: 481 FKLEQEEYVAEEIEWSFIEFNDNQPCIDLIENKL-GILSLLDEESRLPAGSDESWTQKLY 539
Query: 527 QTF---KDHKRFSKPKLSPSDFTICHYAGDVTYQTEYFLDKNKDYVVAEHQSLLYAST-- 581
QT ++ FSKP+ + F + HYA DV Y E F++KN+D V H +L AST
Sbjct: 540 QTLDKSPTNEVFSKPRFGQTKFIVSHYALDVAYDVEGFIEKNRDTVSDGHLEVLKASTNE 599
Query: 582 --CPFVSGLFPPSP--EETSKQ------------------SKFSSIGSRFKQQLQSLLET 619
+ GL + EET K ++ ++GS FKQ L L+ T
Sbjct: 600 TLINILEGLENAAKKLEETKKAELEQNNPGNKKPGPARTVNRKPTLGSMFKQSLIELMST 659
Query: 620 LSSTEPHYIRCVKPNNLLKPAIFDNKNVLLQLRCGGVMEAIRISCAGYPTRKAFDEFVDR 679
++ST HYIRC+KPN + FDN VL QLR GV+E IRISCAG+P+R F+EFV R
Sbjct: 660 INSTNVHYIRCIKPNADKEAWQFDNLMVLSQLRACGVLETIRISCAGFPSRWTFEEFVLR 719
Query: 680 FGLLAP--------EVLDGSSEEVTACKRILKNVWLEG---YQIGKTKVFLRAGQMAELD 728
+ +L P + + + +++ + +++ + ++ YQIG TK+F +AG +A L+
Sbjct: 720 YYILIPHEEWDLIFQKKETTEDDIISVVKMILDATVKDKTKYQIGNTKIFFKAGMLAYLE 779
Query: 729 TRRSEILGKSASIIQRKVRSYLARQSFILLRVSALQIQAACRGQLARQVFEGMRREASSL 788
RS + S IQ+K+R+ R ++ + + Q+ RG + R + S+
Sbjct: 780 KLRSNKMHNSIVTIQKKIRAKYYRNQYLKISQAIKIWQSNTRGFIIRHRVYHEMKVHSAT 839
Query: 789 LIQRCLRMHIAKKAYKELYASAVSIQTGMRVMAAHCELHSRRRTSAAIIIQSHCRKYLAL 848
LIQ R + +K + + +++QT +R +L +AA+ IQS R +
Sbjct: 840 LIQATYRGYAIRKNVFNVLITIINLQTRIREELKRKQLKREHEYNAAVTIQSKVRTFEPR 899
Query: 849 LNFTKLKKAAIATQCAWRGKVARRELRKLKMAARETGALQDAKNKLEKQVEDLTLRLQLE 908
F K+ + Q R + A+ LR+LK A+ L++ KLE +V +LT L
Sbjct: 900 STFLNTKRDTVVVQSLIRRRAAQGRLRQLKSDAKSVHHLKEVSYKLENKVIELTQNL--- 956
Query: 909 KRLRVDVEEAKAKENERLQSALQKMQLQFKETKVLLEK------------EREATKKLEA 956
+K KEN+ + ++++Q+Q +E+ L E + + K +E
Sbjct: 957 --------ASKVKENKEMTERIKELQVQVEESAKLQETLENMKKEHLVNIDNQKNKDMEL 1008
Query: 957 RVPVIQEVPAVDHAL------LEKLSSENEKLKTLVSSLEKKIDETEKRYEEEAKVSEER 1010
+ + + + + L LE++ ++ +LK ++DET+K E ++ +
Sbjct: 1009 QKTIEDNLQSTEQNLKNAQLELEEMVKQHNELKEESRKQLDELDETKKALVEHQTLNGDL 1068
Query: 1011 LKQALDAESKVIQMKTAMQR-------LEEKFADIEFANHVLQKQSLSINSPVKTAVENL 1063
+ + ++ +++TAM L + SL +++ + ++
Sbjct: 1069 QNEVKSLKEEISRLQTAMSLGTVTTSVLPQTPLKDVMGGSTANYNSLMLDNAELSPGKSR 1128
Query: 1064 STPVSEKLENGHHVAEEPYDAD-----TYVTPVKQFVAESDVKLKRSCSERHHGSFDSLV 1118
+TP+S G+H+ D D T + + E L + +E F+
Sbjct: 1129 TTPMS-----GNHIDSLNIDQDNGANATQINEELYRLLEDTEILNQEITEGLLKGFEVPD 1183
Query: 1119 NCVSKNIGFNHGKPIAAFTIYKCLLHWK-SFEAERSSVFDRLIQMIGSAIEDQDDNALM- 1176
V+ + A I W+ + S +++ I + N L+
Sbjct: 1184 AGVAIQLSKRDVVYPARILIIVLSEMWRFGLTKQSESFLAQVLTTIQKVVTQLKGNDLIP 1243
Query: 1177 --AYWLSNTSALLFLLEQSLKTGTSTNATPNGKPPNPTSLFGRMTKSFLSSPSSANLASP 1234
+WL+N L + +L + + NG + K ++
Sbjct: 1244 SGVFWLANVRELYSFVVFALNSILTEETFKNG-------MTDEEYKEYV----------- 1285
Query: 1235 SSVVRKVEAKYPALLFKQQLTAYLEKIYGIIRDNLTKELTSALALCIQAPRTSKGVLRSG 1294
S+V +++ + AL + +L+K ++ L K+ +A+ + P S G SG
Sbjct: 1286 -SLVTELKDDFEALSY-NIYNIWLKK----LQKQLQKKAINAVVISESLPGFSAGE-TSG 1338
Query: 1295 --RSFGKDSPMVHWQSIIESLNTLLCTLKENFIPPVLIRKIFSQTFAFINVQLFN----- 1347
++ I+ N++ +K I + + + +++ FN
Sbjct: 1339 FLNKIFANTEEYTMDDILTFFNSIYWCMKSFHIETEVFHAVVTTLLNYVDAICFNELIMK 1398
Query: 1348 ------SNGEYVKAGLAELELWCCQAKEEYAGSSWDELKHIRQAVGFLVIHQKYRISYDE 1401
G + + LE WC K + L+H+ Q L + +KY I +
Sbjct: 1399 RNFLSWKRGLQLNYNVTRLEEWC---KTHGLTGGTECLQHLIQTAKLLQV-RKYTIEDID 1454
Query: 1402 IVNDLCPILSVQQLCKICTLYWDDNYNTRSVSPHVLASMRMDLDSNDA--MNDSFLLDDS 1459
I+ +C L+ QL K+ + Y +Y S P + D+ +A NDS + S
Sbjct: 1455 ILRGICYSLTPAQLQKLISQYQVADY--ESPIPQEILRYVADIVKKEAALSNDSKGHEHS 1512
Query: 1460 SSI 1462
S I
Sbjct: 1513 SGI 1515
>MYS4_YEAST (P32492) Myosin-4 isoform
Length = 1471
Score = 635 bits (1637), Expect = 0.0
Identities = 400/1066 (37%), Positives = 592/1066 (55%), Gaps = 89/1066 (8%)
Query: 8 VGTHVWIEDSDIAWIDGEVVGVNGEE----IKVLCTSGKTVVVKASKIYHKDTEV----- 58
VGT W + WI GEV + E +++ G+TV ++ + + D
Sbjct: 5 VGTKCWYPHKEQGWIGGEVTKNDFFEGTFHLELKLEDGETVSIETNSFENDDDHPTLPVL 64
Query: 59 --PP--SGVDDMTKLAYLHEPGVLNNLRSRYDINEIYTYTGNILIAVNPFIKLPHLYDIH 114
PP DD+T L+YL+EP VL+ ++ RY +IYTY+G +LIA NPF K+ HLY
Sbjct: 65 RNPPILESTDDLTTLSYLNEPAVLHAIKKRYMNGQIYTYSGIVLIAANPFDKVDHLYSRE 124
Query: 115 MMAQYKGVAFGELSPHPFAVADAAYRLMINEGISQSILVSGESGAGKTETTKLLMRYLAY 174
M+ Y EL PH FA+A+ AYR M++E +Q+++VSGESGAGKT + K +MRY A
Sbjct: 125 MIQNYSSKRKDELEPHLFAIAEEAYRFMVHEKANQTVVVSGESGAGKTVSAKYIMRYFAS 184
Query: 175 M---GGRAAVAEGRTVEQKVLESNPVLEAFGNAKTVRNNNSSRFGKFVEIQFDQKGRISG 231
+ R E +E ++L +NP++EAFGNAKT RN+NSSRFGK+++I FD+ I G
Sbjct: 185 VQESNNREGEVEMSQIESQILATNPIMEAFGNAKTTRNDNSSRFGKYLQILFDENTTIRG 244
Query: 232 AAIRTYLLERSRVCQLSDPERNYHCFYMLCAAPAEVVKK-YKLGHPRTFHYLNQSNCYEL 290
+ IRTYLLE+SR+ + ERNYH FY + E VK+ L P+ +HY NQ +
Sbjct: 245 SKIRTYLLEKSRLVYQPETERNYHIFYQILEGLPEPVKQELHLSSPKDYHYTNQGGQPNI 304
Query: 291 EGLDESKEYITIRRAMDVVGISIENQDAIFQVVAAILHLGNIEFVKGDEIDSSMPKDEKS 350
G+DE++EY A+ +VGI+ E Q IF+++A +LH+GNIE +K D+S+ +E++
Sbjct: 305 AGIDEAREYKITTDALSLVGINHETQLGIFKILAGLLHIGNIE-MKMTRNDASLSSEEQN 363
Query: 351 RFHLQTAAELFMCDANALEDSLCKRVIVTRDETITKWLDPEAAALSRDALAKIVYTRLFD 410
LQ A EL D + K+ IVTR E I L+ A ++RD++AK +Y+ LFD
Sbjct: 364 ---LQIACELLGIDPFNFAKWIVKKQIVTRSEKIVTNLNYNQALIARDSVAKFIYSTLFD 420
Query: 411 WLVDTINNSIGQDPESK------SLIGVLDIYGFESFKNNSFEQFCINLTNEKLQQHFNQ 464
WLVD IN ++ DPE S IG+LDIYGFE F+ NSFEQFCIN NEKLQQ FNQ
Sbjct: 421 WLVDNINKTL-YDPELDQQDHVFSFIGILDIYGFEHFEKNSFEQFCINYANEKLQQEFNQ 479
Query: 465 HVFKMEQEEYKKEEIDWSYIEFVDNQDILDLIEKKPGGIISLLDEACMFPRSTHETFSQK 524
HVFK+EQEEY KEEI+WS+IEF DNQ +DLIE K GI+SLLDE P + E+++ K
Sbjct: 480 HVFKLEQEEYVKEEIEWSFIEFSDNQPCIDLIENKL-GILSLLDEESRLPSGSDESWASK 538
Query: 525 LYQTFK---DHKRFSKPKLSPSDFTICHYAGDVTYQTEYFLDKNKDYVVAEHQSLLYAST 581
LY F ++ FSKP+ + F + HYA DV Y+ E F++KN+D V H + A+T
Sbjct: 539 LYSAFNKPPSNEVFSKPRFGQTKFIVSHYAVDVEYEVEGFIEKNRDSVSLGHLDVFKATT 598
Query: 582 CPFVSGLF-------PPSPEETSKQSKF----------SSIGSRFKQQLQSLLETLSSTE 624
P + +PEE + + K ++GS FK+ L L+ ++ST
Sbjct: 599 NPIFKQILDNRELRSDDAPEEQNTEKKIMIPARLSQKKPTLGSMFKKSLGELMAIINSTN 658
Query: 625 PHYIRCVKPNNLLKPAIFDNKNVLLQLRCGGVMEAIRISCAGYPTRKAFDEFVDRFGLLA 684
HYIRC+KPN+ KP FDN VL QLR GV+E IRISCAG+P+R FDEFV R+ LL
Sbjct: 659 VHYIRCIKPNSEKKPWEFDNLMVLSQLRACGVLETIRISCAGFPSRWTFDEFVQRYFLLT 718
Query: 685 PEVL--------DGSSEE-VTACKRILKNVWLEG--YQIGKTKVFLRAGQMAELDTRRSE 733
L D E V C+ IL + YQIG TK+F +AG +A L+ R+
Sbjct: 719 DYSLWSGILYNPDLPKEAIVNFCQSILDATISDSAKYQIGNTKIFFKAGMLAFLEKLRTN 778
Query: 734 ILGKSASIIQRKVRSYLARQSFILLRVSALQIQAACRGQLARQVFEGMRREASSLLIQRC 793
+ + IIQ+K+R+ R ++ S + Q+ R L R + + +++L+Q
Sbjct: 779 KMNEICIIIQKKIRARYYRLQYLQTMESIKKCQSQIRSLLVRTRVDHELKTRAAILLQTN 838
Query: 794 LRMHIAKKAYKELYASAVSIQTGMRVMAAHCELHSRRRTSAAIIIQSHCRKYLALLNFTK 853
+R ++ Y+ + +Q + ++ + AA+IIQS+ R Y ++
Sbjct: 839 IRALWKREYYRAAIGQIIKLQCTCKRKLILDSVNRKFMLMAAVIIQSYIRSYGHKTDYRT 898
Query: 854 LKKAAIATQCAWRGKVARRELRKLKMAARE--------TGALQDA---KNKLEKQVEDLT 902
LK+++I Q A R ++ARR L+ E G L++A KN +E L
Sbjct: 899 LKRSSILVQSAMRMQLARRRYIVLQKEVEERNIRASYGIGLLEEAIEFKNSFILNLEMLN 958
Query: 903 -LRLQLEKRLRVDVEEAKAKENERLQ----------SALQKMQLQFKET----KVLLEKE 947
+L + L+ D+ +K+ + + S L+ +Q++ T L E++
Sbjct: 959 DSYTRLTQLLQGDLSNIPSKQRQEYETIVNGYNDKISKLKTLQVEIMNTLNKKNALKERK 1018
Query: 948 REATKKLEARVPVIQEVPAVDHALLEKLSSENEKLKTLVSSLEKKI 993
++ + +++ +Q + A+ +LS E + +K ++ +E I
Sbjct: 1019 KKQSSLIQSH---MQSLAAIKGNKPSRLSDEVKSMKQELAFIENVI 1061
>MYS2_DICDI (P08799) Myosin II heavy chain, non muscle
Length = 2116
Score = 629 bits (1623), Expect = e-179
Identities = 401/1053 (38%), Positives = 612/1053 (58%), Gaps = 39/1053 (3%)
Query: 24 GEVVGVNGEEIKVLCTSGKTVVVKASKIYHKDTEVPPSGVDDMTKLAYLHEPGVLNNLRS 83
GE+V + G+ VK ++ + GV+DM++L+YL+EP V +NLR
Sbjct: 50 GEIVSETSDSFTFKTVDGQDRQVKKDDANQRNP-IKFDGVEDMSELSYLNEPAVFHNLRV 108
Query: 84 RYDINEIYTYTGNILIAVNPFIKLPHLYDIHMMAQYKGVAFGELSPHPFAVADAAYRLMI 143
RY+ + IYTY+G L+AVNPF ++P +Y M+ +KG E++PH FA++D AYR M+
Sbjct: 109 RYNQDLIYTYSGLFLVAVNPFKRIP-IYTQEMVDIFKGRRRNEVAPHIFAISDVAYRSML 167
Query: 144 NEGISQSILVSGESGAGKTETTKLLMRYLAYMGGRAAVAEGRTVEQKVLESNPVLEAFGN 203
++ +QS+L++GESGAGKTE TK +++YLA + GR +EQ++L++NP+LEAFGN
Sbjct: 168 DDRQNQSLLITGESGAGKTENTKKVIQYLASVAGRNQANGSGVLEQQILQANPILEAFGN 227
Query: 204 AKTVRNNNSSRFGKFVEIQFDQKGRISGAAIRTYLLERSRVCQLSDPERNYHCFYMLCA- 262
AKT RNNNSSRFGKF+EIQF+ G ISGA+I++YLLE+SRV S+ ERNYH FY L A
Sbjct: 228 AKTTRNNNSSRFGKFIEIQFNNAGFISGASIQSYLLEKSRVVFQSETERNYHIFYQLLAG 287
Query: 263 APAEVVKKYKLGHPRTFHYLNQSNCYELEGLDESKEYITIRRAMDVVGISIENQDAIFQV 322
A AE K L P +F+YLNQS +++G+ +S+E+ R+AMD+VG S E Q +IF++
Sbjct: 288 ATAEEKKALHLAGPESFNYLNQSGYVDIKGVSDSEEFKITRQAMDIVGFSQEEQMSIFKI 347
Query: 323 VAAILHLGNIEFVKGDEIDSSMPKDEKSRFHLQTAAELFMCDANALEDSLCKRVIVTRDE 382
+A ILHLGNI+F KG + ++ KD+ + L A+ +F + + LE +L + I+ +
Sbjct: 348 IAGILHLGNIKFEKGAG-EGAVLKDKTA---LNAASTVFGVNPSVLEKALMEPRILAGRD 403
Query: 383 TITKWLDPEAAALSRDALAKIVYTRLFDWLVDTINNSIGQDPESKSLIGVLDIYGFESFK 442
+ + L+ E ++ SRDAL K +Y RLF WLV INN + Q+ ++ IGVLDI GFE FK
Sbjct: 404 LVAQHLNVEKSSSSRDALVKALYGRLFLWLVKKINNVLCQERKA-YFIGVLDISGFEIFK 462
Query: 443 NNSFEQFCINLTNEKLQQHFNQHVFKMEQEEYKKEEIDWSYIEF-VDNQDILDLIE-KKP 500
NSFEQ CIN TNEKLQQ FN H+FK+EQEEY KE+I+W++I+F +D+Q +DLI+ ++P
Sbjct: 463 VNSFEQLCINYTNEKLQQFFNHHMFKLEQEEYLKEKINWTFIDFGLDSQATIDLIDGRQP 522
Query: 501 GGIISLLDEACMFPRSTHETFSQKLYQTF-KDHKRFSKPKLSPSDFTICHYAGDVTYQTE 559
GI++LLDE +FP +T T KL+ F K + ++ +P+ S ++F + HYAG V Y+ +
Sbjct: 523 PGILALLDEQSVFPNATDNTLITKLHSHFSKKNAKYEEPRFSKTEFGVTHYAGQVMYEIQ 582
Query: 560 YFLDKNKDYVVAEHQSLLYASTCPFVSGLF--PPSPEETSKQSKFSSIGSRFKQQLQSLL 617
+L+KNKD + + + S+ V+ LF P K + F ++ +++K+QL SL+
Sbjct: 583 DWLEKNKDPLQQDLELCFKDSSDNVVTKLFNDPNIASRAKKGANFITVAAQYKEQLASLM 642
Query: 618 ETLSSTEPHYIRCVKPNNLLKPAIFDNKNVLLQLRCGGVMEAIRISCAGYPTRKAFDEFV 677
TL +T PH++RC+ PNN PA ++K VL QLRC GV+E IRI+ G+P R + +FV
Sbjct: 643 ATLETTNPHFVRCIIPNNKQLPAKLEDKVVLDQLRCNGVLEGIRITRKGFPNRIIYADFV 702
Query: 678 DRFGLLAPEVLDGSSEEVTACKRILK--NVWLEGYQIGKTKVFLRAGQMAELDTRRSEIL 735
R+ LLAP V + + A +LK N+ E Y+ G TK+F RAGQ+A ++ R + +
Sbjct: 703 KRYYLLAPNVPRDAEDSQKATDAVLKHLNIDPEQYRFGITKIFFRAGQLARIEEAREQRI 762
Query: 736 GKSASIIQRKVRSYLARQSFILLR---VSALQIQAACRGQLARQVFEGMR--REASSLLI 790
+ IQ R ++AR+ + R V+A IQ R + + + + +A LL
Sbjct: 763 SEIIKAIQAATRGWIARKVYKQAREHTVAARIIQQNLRAYIDFKSWPWWKLFSKARPLLK 822
Query: 791 QRCLRMHIAKKAYKELYASAVSIQTGMRVMAAHCELHSRRRTSAAIIIQSHCRKYLALLN 850
+R I +K + L S T E + S + +Q + L
Sbjct: 823 RRNFEKEIKEKEREIL--ELKSNLTDSTTQKDKLEKSLKDTESNVLDLQRQLKAEKETLK 880
Query: 851 FTKLKKAAIATQ---CAWRGKVARRELRKLKMAARETGALQDAKNKLEKQVEDLTLRLQL 907
K A+ Q R + EL + K+A LQ+ K +E++V DL LQ
Sbjct: 881 AMYDSKDALEAQKRELEIRVEDMESELDEKKLALEN---LQNQKRSVEEKVRDLEEELQE 937
Query: 908 EKRLRVDVEEAKAKENERLQSALQKMQLQFKETKVLLEKEREATKKLEARVPVIQEVPAV 967
E++LR +E+ K K E L+ ++++ +T LEK ++ +K EV +
Sbjct: 938 EQKLRNTLEKLKKKYEEELEE-MKRVNDGQSDTISRLEKIKDELQK---------EVEEL 987
Query: 968 DHALLEKLSSENEKLKTLVSSLEKKIDETEKRYEEEAKVSEERLKQALDAESKVIQMKTA 1027
+ E+ + KT V L+ ++D+ R + E K E L+Q E ++ Q++ A
Sbjct: 988 TESFSEESKDKGVLEKTRV-RLQSELDDLTVRLDSETKDKSELLRQKKKLEEELKQVQEA 1046
Query: 1028 MQRLEEKFADIEFANHVLQKQSLSINSPVKTAV 1060
+ E AN LQ + +N + V
Sbjct: 1047 LAAETAAKLAQEAANKKLQGEYTELNEKFNSEV 1079
Score = 51.6 bits (122), Expect = 2e-05
Identities = 56/258 (21%), Positives = 119/258 (45%), Gaps = 34/258 (13%)
Query: 876 KLKMAARETGALQDAKNKLEKQVEDLTLRLQLEKRLRVDVEEAKAKENERLQSALQKMQL 935
K++ A RE + K KLE + DL+ +L E + R+ +E++K +K++
Sbjct: 1576 KVEEAQREVVTIDRLKKKLESDIIDLSTQLDTETKSRIKIEKSK-----------KKLEQ 1624
Query: 936 QFKETKVLLEKEREATKKLEARVPVIQEVPAVDHALLEK---LSSENEKLKTLVSSLEKK 992
E + E +A + E R V QEV + L + L++ +K+K+LV+ +
Sbjct: 1625 TLAERRAAEEGSSKAADE-EIRKQVWQEVDELRAQLDSERAALNASEKKIKSLVA----E 1679
Query: 993 IDETEKRYEEE--AKVSEERLKQALDAESKVI------------QMKTAMQRLEEKFADI 1038
+DE +++ E+E AK + K+AL+ E + + +++ + +RL + DI
Sbjct: 1680 VDEVKEQLEDEILAKDKLVKAKRALEVELEEVRDQLEEEEDSRSELEDSKRRLTTEVEDI 1739
Query: 1039 EFANHVLQKQSLSINSPVKTAVENLSTPVSEKLENGHHVAEEPYDADTYVTPVKQFVAES 1098
+ +Q+ ++ K +++ T + + + E + + F+A+
Sbjct: 1740 KKKYDAEVEQNTKLDEAKKKLTDDVDTLKKQLEDEKKKLNESERAKKRLESENEDFLAKL 1799
Query: 1099 DVKLK-RSCSERHHGSFD 1115
D ++K RS +E+ ++
Sbjct: 1800 DAEVKNRSRAEKDRKKYE 1817
Score = 47.4 bits (111), Expect = 3e-04
Identities = 69/279 (24%), Positives = 125/279 (44%), Gaps = 42/279 (15%)
Query: 867 GKVARRELRKLKMAARETGALQDAKNKLEKQVEDLTLRL-----------QLEKRLRVDV 915
G+VAR + +L+ ++ K K+E +ED + +L +L+K+L ++
Sbjct: 1178 GEVARLQ-GELEAEQLAKSNVEKQKKKVELDLEDKSAQLAEETAAKQALDKLKKKLEQEL 1236
Query: 916 EEAKAK------ENERLQSALQKMQLQFKETKVLLEKEREATKKLE-ARVPVIQEVPAVD 968
E + + +N S + ++ F K+ LE E++A + LE R+ + E+ V+
Sbjct: 1237 SEVQTQLSEANNKNVNSDSTNKHLETSFNNLKLELEAEQKAKQALEKKRLGLESELKHVN 1296
Query: 969 HALLE--KLSSENEK----LKTLVSSLEKKIDE--------TEKRYEEEAKVSEERLKQA 1014
L E K NEK L+ VS L+ +I+E TE + ++E+++ E + + A
Sbjct: 1297 EQLEEEKKQKESNEKRKVDLEKEVSELKDQIEEEVASKKAVTEAKNKKESELDEIKRQYA 1356
Query: 1015 ---LDAESKVIQMKTAMQRLEEKFADIEFANHVLQKQSLS---INSPVKTAVENLSTPVS 1068
+ V Q+KT + EE E A L + S ++ AV+NL +
Sbjct: 1357 DVVSSRDKSVEQLKTLQAKNEELRNTAEEAEGQLDRAERSKKKAEFDLEEAVKNLEEETA 1416
Query: 1069 EKL--ENGHHVAEEPY-DADTYVTPVKQFVAESDVKLKR 1104
+K+ E AE Y + + K +E V++KR
Sbjct: 1417 KKVKAEKAMKKAETDYRSTKSELDDAKNVSSEQYVQIKR 1455
Score = 46.2 bits (108), Expect = 7e-04
Identities = 44/217 (20%), Positives = 93/217 (42%), Gaps = 28/217 (12%)
Query: 873 ELRKLKMAARETGA-LQDAKNKLEKQVEDLTLRLQLEKRLRVDVEEAKAKENERLQSALQ 931
ELR+ A ++ + + +K +E ++ED LQ E +D +E LQ +
Sbjct: 1906 ELRETVEEAEDSKSEAEQSKRLVELELEDARRNLQKE----IDAKEIAEDAKSNLQREIV 1961
Query: 932 KMQLQFKETKVLLEKEREATKKLEARVPVIQEVPAVDHALLEKLSSENEKLKTLVSSLEK 991
+ + + +E + + K+LEA + + + + EN+K++T + K
Sbjct: 1962 EAKGRLEEESIARTNSDRSRKRLEAEIDALTAQVDAEQKAKNQQIKENKKIETELKEYRK 2021
Query: 992 KIDETEKRYEEEAKVSEERLKQALDAESKVIQMKTAMQRLEEKFADIEFANHVLQKQSLS 1051
K E+EK +E V E +++T +R +++ AD Q+Q L+
Sbjct: 2022 KFGESEKTKTKEFLVVE--------------KLETDYKRAKKEAAD-------EQQQRLT 2060
Query: 1052 INSPVKTAVENLS--TPVSEKLENGHHVAEEPYDADT 1086
+ + ++ + +S +KL+ H + + +T
Sbjct: 2061 VENDLRKHLSEISLLKDAIDKLQRDHDKTKRELETET 2097
Score = 44.3 bits (103), Expect = 0.003
Identities = 44/192 (22%), Positives = 80/192 (40%), Gaps = 23/192 (11%)
Query: 875 RKLKMAARETGALQDAKNKLEKQVEDLTLRLQLEKRLRVDVEEAKAK---ENE------- 924
+K + L +AK KL V+ L +L+ EK+ + E AK + ENE
Sbjct: 1741 KKYDAEVEQNTKLDEAKKKLTDDVDTLKKQLEDEKKKLNESERAKKRLESENEDFLAKLD 1800
Query: 925 -------RLQSALQKMQLQFKETKVLLEKEREATKKLEARVPVIQEVPAVDHALLEKLSS 977
R + +K + K+TK L EA K + + + +D L KL
Sbjct: 1801 AEVKNRSRAEKDRKKYEKDLKDTKYKLND--EAATKTQTEIGAAKLEDQIDE-LRSKLEQ 1857
Query: 978 ENEKLKTLVSS---LEKKIDETEKRYEEEAKVSEERLKQALDAESKVIQMKTAMQRLEEK 1034
E K S LE +ID + E+E K+ K+ E ++ +++ ++ E+
Sbjct: 1858 EQAKATQADKSKKTLEGEIDNLRAQIEDEGKIKMRLEKEKRALEGELEELRETVEEAEDS 1917
Query: 1035 FADIEFANHVLQ 1046
++ E + +++
Sbjct: 1918 KSEAEQSKRLVE 1929
Score = 42.4 bits (98), Expect = 0.010
Identities = 43/178 (24%), Positives = 90/178 (50%), Gaps = 31/178 (17%)
Query: 870 ARRELRKLKMAARETGALQDAKNKLEKQVEDLTLRLQLE-----------KRLRVDVE-- 916
ARR L+K ++ A+E +DAK+ L++++ + RL+ E KRL +++
Sbjct: 1935 ARRNLQK-EIDAKEIA--EDAKSNLQREIVEAKGRLEEESIARTNSDRSRKRLEAEIDAL 1991
Query: 917 ------EAKAK-----ENERLQSALQKMQLQFKETKVLLEKEREATKKLEARVPVIQEVP 965
E KAK EN+++++ L++ + +F E++ KE +KLE ++
Sbjct: 1992 TAQVDAEQKAKNQQIKENKKIETELKEYRKKFGESEKTKTKEFLVVEKLETDYKRAKKEA 2051
Query: 966 AVDHALLEKLSSENEKLKTL--VSSLEKKIDETEKRYEEEAKVSEERLKQALDAESKV 1021
A + ++L+ EN+ K L +S L+ ID+ ++ +++ + E ++ + K+
Sbjct: 2052 ADEQQ--QRLTVENDLRKHLSEISLLKDAIDKLQRDHDKTKRELETETASKIEMQRKM 2107
Score = 38.9 bits (89), Expect = 0.11
Identities = 51/250 (20%), Positives = 99/250 (39%), Gaps = 33/250 (13%)
Query: 887 LQDAKNKLEKQVEDLTLRLQLEKRLRVDVEEAKAKENERLQSALQKMQLQFKETKVLLEK 946
L+D+K +L +VED+ + E ++EAK K L + ++ Q ++ K L +
Sbjct: 1725 LEDSKRRLTTEVEDIKKKYDAEVEQNTKLDEAKKK----LTDDVDTLKKQLEDEKKKLNE 1780
Query: 947 EREATKKLEAR-----VPVIQEVPAVDHALLEKLSSENE--------------KLKTLVS 987
A K+LE+ + EV A ++ E + K +T +
Sbjct: 1781 SERAKKRLESENEDFLAKLDAEVKNRSRAEKDRKKYEKDLKDTKYKLNDEAATKTQTEIG 1840
Query: 988 S--LEKKIDETEKRYEEEAKVSEERLKQALDAESKVIQMKTAMQ-------RLEEKFADI 1038
+ LE +IDE + E+E + + K E ++ ++ ++ RLE++ +
Sbjct: 1841 AAKLEDQIDELRSKLEQEQAKATQADKSKKTLEGEIDNLRAQIEDEGKIKMRLEKEKRAL 1900
Query: 1039 EFANHVLQKQSLSINSPVKTAVENLSTPVSEKLENGHHVAEEPYDADTYVTPVKQFVAES 1098
E L ++++ K+ E V +LE+ ++ DA K +
Sbjct: 1901 EGELEEL-RETVEEAEDSKSEAEQSKRLVELELEDARRNLQKEIDAKEIAEDAKSNLQRE 1959
Query: 1099 DVKLKRSCSE 1108
V+ K E
Sbjct: 1960 IVEAKGRLEE 1969
>MY5C_HUMAN (Q9NQX4) Myosin Vc (Myosin 5C)
Length = 1742
Score = 622 bits (1603), Expect = e-177
Identities = 399/1111 (35%), Positives = 613/1111 (54%), Gaps = 71/1111 (6%)
Query: 12 VWIEDSDIAWIDGEVVG---VNGEEIKVLCTSGKTVVVKASKIYHKDTEVPPS------- 61
VWI D + W E+ V + +++L G + + +PP
Sbjct: 13 VWIPDPEEVWKSAEIAKDYRVGDKVLRLLLEDGTELDYSVNP-----ESLPPLRNPDILV 67
Query: 62 GVDDMTKLAYLHEPGVLNNLRSRYDINE-IYTYTGNILIAVNPFIKLPHLYDIHMMAQYK 120
G +D+T L+YLHEP VL+NLR R+ ++ IYTY+G IL+A+NP+ +LP +Y ++ Y
Sbjct: 68 GENDLTALSYLHEPAVLHNLRIRFAESKLIYTYSGIILVAMNPYKQLP-IYGDAIIHAYS 126
Query: 121 GVAFGELSPHPFAVADAAYRLMINEGISQSILVSGESGAGKTETTKLLMRYLAYMGGRAA 180
G G++ PH FAVA+ AY+ M +QSI+VSGESGAGKT + + MRY A + +
Sbjct: 127 GQNMGDMDPHIFAVAEEAYKQMARNNRNQSIIVSGESGAGKTVSARYAMRYFATVSKSGS 186
Query: 181 VAEGRTVEQKVLESNPVLEAFGNAKTVRNNNSSRFGKFVEIQFDQKGRISGAAIRTYLLE 240
A VE KVL SNP+ EA GNAKT RN+NSSRFGK+ EI FD++ +I GA + TYLLE
Sbjct: 187 NAH---VEDKVLASNPITEAVGNAKTTRNDNSSRFGKYTEISFDEQNQIIGANMSTYLLE 243
Query: 241 RSRVCQLSDPERNYHCFYMLCA-APAEVVKKYKLGHPRTFHYLNQSNCYELEGLDESKEY 299
+SRV S+ ERNYH FY LCA A K KLG F+Y +EG+++ E
Sbjct: 244 KSRVVFQSENERNYHIFYQLCASAQQSEFKHLKLGSAEEFNYTRMGGNTVIEGVNDRAEM 303
Query: 300 ITIRRAMDVVGISIENQDAIFQVVAAILHLGNIEFVKGDEIDSSMPKDEKSRFHLQTAAE 359
+ ++ ++G + Q +F+++AAILHLGN++ SS+ +D+ HL+ E
Sbjct: 304 VETQKTFTLLGFKEDFQMDVFKILAAILHLGNVQITAVGNERSSVSEDDS---HLKVFCE 360
Query: 360 LFMCDANALEDSLCKRVIVTRDETITKWLDPEAAALSRDALAKIVYTRLFDWLVDTINNS 419
L ++ + LC R IVT ET+ K + A +RDALAK +Y LFD++V+ IN +
Sbjct: 361 LLGLESGRVAQWLCNRKIVTSSETVVKPMTRPQAVNARDALAKKIYAHLFDFIVERINQA 420
Query: 420 IGQDPESKSLIGVLDIYGFESFKNNSFEQFCINLTNEKLQQHFNQHVFKMEQEEYKKEEI 479
+ + + IGVLDIYGFE+F NSFEQFCIN NEKLQQ FN HVFK+EQEEY KE+I
Sbjct: 421 LQFSGKQHTFIGVLDIYGFETFDVNSFEQFCINYANEKLQQQFNMHVFKLEQEEYMKEDI 480
Query: 480 DWSYIEFVDNQDILDLIEKKPGGIISLLDEACMFPRSTHETFSQKLYQTFKD-HKRFSKP 538
W+ I+F DNQ ++DLIE K GI+ LLDE C+ P T E + QKLY F + + F KP
Sbjct: 481 PWTLIDFYDNQPVIDLIEAKM-GILELLDEECLLPHGTDENWPQKLYNNFVNRNPLFEKP 539
Query: 539 KLSPSDFTICHYAGDVTYQTEYFLDKNKDYVVAEHQSLLYASTCPFVSGLF-----PPSP 593
++S + F I H+A V Y+ E FL+KN+D V +L AS + F PPSP
Sbjct: 540 RMSNTSFVIQHFADKVEYKCEGFLEKNRDTVYDMLVEILRASKFHLCANFFQENPTPPSP 599
Query: 594 ------EETSKQ-----SKF--SSIGSRFKQQLQSLLETLSSTEPHYIRCVKPNNLLKPA 640
+++KQ SK +++GS+F+ L L+ETL++T PHY+RC+KPN+ P
Sbjct: 600 FGSMITVKSAKQVIKPNSKHFRTTVGSKFRSSLYLLMETLNATTPHYVRCIKPNDEKLPF 659
Query: 641 IFDNKNVLLQLRCGGVMEAIRISCAGYPTRKAFDEFVDRFGLLAPEVLDGSSEEVTACKR 700
FD+K ++ QLR GV+E IRIS YP+R + EF R+G+L + S++ CK
Sbjct: 660 EFDSKRIVQQLRACGVLETIRISAQSYPSRWTYIEFYSRYGILMTKQELSFSDKKEVCKV 719
Query: 701 ILKNVWLEG--YQIGKTKVFLRAGQMAELDTRRSEILGKSASIIQRKVRSYLARQSFILL 758
+L + + YQ GKTK+F RAGQ+A L+ R + L +S ++Q+ +R +L R+ F+
Sbjct: 720 VLHRLIQDSNQYQFGKTKIFFRAGQVAYLEKLRLDKLRQSCVMVQKHMRGWLQRKKFLRE 779
Query: 759 RVSALQIQAACRGQ--LARQVFEGMRREA-SSLLIQRCLRMHIAKKAYKELYASAVSIQT 815
R +AL IQ RGQ + + + +EA ++++IQ+ R ++ + Y+ + + +++Q
Sbjct: 780 RRAALIIQQYFRGQQTVRKAITAVALKEAWAAIIIQKHCRGYLVRSLYQLIRMATITMQA 839
Query: 816 GMRVMAAHCELHSRRRTSAAIIIQSHCRKYLALLNFTKLKKAAIATQCAWRGKVARRELR 875
R A A+I+Q + R +LA F +++ + Q +R +R +
Sbjct: 840 YSRGFLARRRYRKMLEEHKAVILQKYARAWLARRRFQSIRRFVLNIQLTYR---VQRLQK 896
Query: 876 KLKMAARETGALQDAKNKLE-------KQVEDLTLRLQLEKRLRVDVEEAKAKENERLQS 928
KL+ +E L + L ++++ L L+ R + EE + + ++
Sbjct: 897 KLEDQNKENHGLVEKLTSLAALRAGDVEKIQKLEAELEKAATHRRNYEEKGKRYRDAVEE 956
Query: 929 ALQKMQLQFKETKVLLEKEREATKKLEARVPVIQEVPAVDHALLEKLSSENEKLKTLVSS 988
L K+Q E + +KE+ K E + +++ + L + + E + L S
Sbjct: 957 KLAKLQKHNSELET--QKEQIQLKLQEKTEELKEKMDNLTKQLFDDVQKEERQRMLLEKS 1014
Query: 989 LEKKIDETEKRYE---EEAKVSEE---RLKQALDAESKVIQ-MKTAMQRLEEKFADI-EF 1040
E K + EK+ + EE K ++ +L+ ++ E +K + RL ++ I EF
Sbjct: 1015 FELKTQDYEKQIQSLKEEIKALKDEKMQLQHLVEGEHVTSDGLKAEVARLSKQVKTISEF 1074
Query: 1041 ANHV--LQKQSLSINSPVKTAVENLSTPVSE 1069
+ LQ Q + + V++ + +SE
Sbjct: 1075 EKEIELLQAQKIDVEKHVQSQKREMREKMSE 1105
Score = 49.3 bits (116), Expect = 8e-05
Identities = 120/602 (19%), Positives = 235/602 (38%), Gaps = 76/602 (12%)
Query: 877 LKMAARETGA-LQDAKNKLEKQVEDLTLRL--------QLEKRLRV--DVEEAKAKENER 925
LK A R + Q K+ EK++E L ++ L+K R D+ E+ E R
Sbjct: 1144 LKKATRVLESHFQSQKDCYEKEIEALNFKVVHLSQEINHLQKLFREENDINESIRHEVTR 1203
Query: 926 LQSALQKMQLQFKETKVLLEKEREATK-KLEARVPVIQ-EVPAVDHALLEKLSSENEKLK 983
L S M FK+ LEK+++ + +L + ++ ++ + + L E + K
Sbjct: 1204 LTSE-NMMIPDFKQQISELEKQKQDLEIRLNEQAEKMKGKLEELSNQLHRSQEEEGTQRK 1262
Query: 984 TLVSSLEKKIDETEKRYE--EEAKVSEERLKQALDAESKV-IQMKTAMQRLEEKFADIEF 1040
L + E E EK + +E + + + LK+ + ES+V + RL + D+E
Sbjct: 1263 ALEAQNEIHTKEKEKLIDKIQEMQEASDHLKKQFETESEVKCNFRQEASRLTLENRDLEE 1322
Query: 1041 ANHVLQKQSLSINSPVKTAVENLSTPVSEKLENGHHVAEEPYDADTYVTPVKQFVAESDV 1100
+ + + VKT + + N H + P + + Q+ E +
Sbjct: 1323 ELDMKDRVIKKLQDQVKTLSKTIGKA------NDVHSSSGPKE----YLGMLQYKREDEA 1372
Query: 1101 KLKRSCSERHHGSFDSLVNCVSKNIGFNHGKPIAAFTIYKCLLHWKSFEAER--SSVFDR 1158
KL ++ +++ + + N + A ++ C+ + S S+ +
Sbjct: 1373 KLIQNL----------ILDLKPRGVVVNMIPGLPAHILFMCVRYADSLNDANMLKSLMNS 1422
Query: 1159 LIQMIGSAIEDQ-DDNALMAYWLSNTSALLFLLEQSLKTGTSTNATPNGKPPNPTSLFGR 1217
I I +++ +D ++++WLSNT L L+Q +G N N L
Sbjct: 1423 TINGIKQVVKEHLEDFEMLSFWLSNTCHFLNCLKQ--YSGEEEFMKHNSPQQNKNCL--- 1477
Query: 1218 MTKSFLSSPSSANLASPSSVVRKVEAKYPALLFKQQLTAYLEKIYGIIRDNLTKELTSAL 1277
++ +L+ ++ V + ++ Q + + I II + E S
Sbjct: 1478 ---------NNFDLSEYRQILSDVAIR----IYHQFIIIMEKNIQPIIVPGML-EYESLQ 1523
Query: 1278 ALCIQAPRTSKGVLRSGRSFGKDSPMVHWQSIIESLNTLLCTLKENFIPPVLIRKIFSQT 1337
+ P R S D+ S+++ L+ T+ +N + P L+R+ Q
Sbjct: 1524 GISGLKPTG----FRKRSSSIDDTDGYTMTSVLQQLSYFYTTMCQNGLDPELVRQAVKQL 1579
Query: 1338 FAFINVQLFNS-----------NGEYVKAGLAELELWCCQAKEEYAGSSWDELKHIRQAV 1386
F I NS G ++ ++ LE W + K + + L+ + QA
Sbjct: 1580 FFLIGAVTLNSLFLRKDMCSCRKGMQIRCNISYLEEW-LKDKNLQNSLAKETLEPLSQAA 1638
Query: 1387 GFLVIHQKYRISYDEIVNDLCPILSVQQLCKICTLYWDDNYNTRSVSPHVLASMRMDLDS 1446
L + +K S + + + C LS Q+ KI Y + + V+P + ++ L+S
Sbjct: 1639 WLLQV-KKTTDSDAKEIYERCTSLSAVQIIKILNSYTPIDDFEKRVTPSFVRKVQALLNS 1697
Query: 1447 ND 1448
+
Sbjct: 1698 RE 1699
>MY2B_SACCA (Q875X4) Myosin-2B (Class V unconventional myosin MYO2B)
(Type V myosin heavy chain MYO2B) (Myosin V MYO2B)
Length = 1419
Score = 615 bits (1587), Expect = e-175
Identities = 399/1094 (36%), Positives = 601/1094 (54%), Gaps = 79/1094 (7%)
Query: 8 VGTHVWIEDSDIAWIDGEVVGVNGEE----IKVLCTSGKTVVVKASKIYHKDT------- 56
VGT W +S+ WI EV + ++ I++ +G + ++ + +
Sbjct: 5 VGTRCWYPNSEAGWIGCEVTKNDFQDGTYHIELTSETGLVIPIETKHLESNNAMENNHEF 64
Query: 57 ----EVPP--SGVDDMTKLAYLHEPGVLNNLRSRYDINEIYTYTGNILIAVNPFIKLPHL 110
PP D+T L+YL+EP VL+ ++ RY+ IYTY+G +LIA NPF K+ L
Sbjct: 65 LPVLRNPPILEATHDLTTLSYLNEPAVLHAIKERYNQRNIYTYSGIVLIATNPFDKVEEL 124
Query: 111 YDIHMMAQYKGVAFGELSPHPFAVADAAYRLMINEGISQSILVSGESGAGKTETTKLLMR 170
Y M+ Y E++PH FA+A+ AYR MIN +Q+I+VSGESGAGKT + K +MR
Sbjct: 125 YSSEMIQAYARKNRDEMAPHIFAIAEEAYREMINNDQNQTIIVSGESGAGKTVSAKYIMR 184
Query: 171 YLAYMGGRAAVAEGRT--------VEQKVLESNPVLEAFGNAKTVRNNNSSRFGKFVEIQ 222
+ A + EG + +E K+L +NPV+EAFGNAKT RN+NSSRFGK+++I
Sbjct: 185 FFASVEEEHFNKEGDSKHQEEMSDIEVKILATNPVMEAFGNAKTTRNDNSSRFGKYLQIL 244
Query: 223 FDQKGRISGAAIRTYLLERSRVCQLSDPERNYHCFY-MLCAAPAEVVKKYKLGHPRTFHY 281
FD I G++I+TYLLERSR+ ERNYH FY ML +++ K+ L + F Y
Sbjct: 245 FDSNKNIIGSSIKTYLLERSRLVFQPTSERNYHIFYQMLSGLSSDMKKQLYLTNAEDFFY 304
Query: 282 LNQSNCYELEGLDESKEYITIRRAMDVVGISIENQDAIFQVVAAILHLGNIEFVKGDEID 341
LNQ + G+D+S EY T ++ VGI E Q IF+++AA+LH+GNIE +K D
Sbjct: 305 LNQGGESTINGIDDSLEYSTTIESLSTVGIDTEVQLQIFKILAALLHIGNIE-IKKTRTD 363
Query: 342 SSMPKDEKSRFHLQTAAELFMCDANALEDSLCKRVIVTRDETITKWLDPEAAALSRDALA 401
+++ + S LQ A EL D + K+ I TR E I L A ++RD++A
Sbjct: 364 ATLSSTDPS---LQKACELLGLDPLTFSKWITKKQINTRSEKIISNLSFNQALVARDSVA 420
Query: 402 KIVYTRLFDWLVDTINNSIGQDPESK---SLIGVLDIYGFESFKNNSFEQFCINLTNEKL 458
K +Y+ LFDWLV INN + S+ S IGVLDIYGFE F+ NSFEQFCIN NEKL
Sbjct: 421 KFIYSSLFDWLVGNINNVLCTSQVSETINSFIGVLDIYGFEHFEQNSFEQFCINYANEKL 480
Query: 459 QQHFNQHVFKMEQEEYKKEEIDWSYIEFVDNQDILDLIEKKPGGIISLLDEACMFPRSTH 518
QQ FN HVFK+EQEEY KEEI+WS+IEF DNQ +DLIE K GI+SLLDE P +
Sbjct: 481 QQEFNHHVFKLEQEEYVKEEIEWSFIEFSDNQPCIDLIENKL-GILSLLDEESRLPAGSD 539
Query: 519 ETFSQKLYQTFK---DHKRFSKPKLSPSDFTICHYAGDVTYQTEYFLDKNKDYVVAEHQS 575
E+++ KLYQTF + F KP+ + F I HYA DVTY+ + F++KNKD +
Sbjct: 540 ESWTTKLYQTFNKPPSNTVFGKPRFGQNKFIISHYAVDVTYEVDGFIEKNKDTISESQLE 599
Query: 576 LLYASTCPFVSGLFPPSPEETSKQ-------------SKFSSIGSRFKQQLQSLLETLSS 622
+L A+T P ++ +F S E ++ ++GS FK+ L L+ET++S
Sbjct: 600 VLKATTNPTLATIFEFSEAENKTNITEQAGTIQRKTINRKPTLGSIFKRSLVELMETINS 659
Query: 623 TEPHYIRCVKPNNLLKPAIFDNKNVLLQLRCGGVMEAIRISCAGYPTRKAFDEFVDRFGL 682
T HYIRC+KPN + FDN VL QLR GV+E I+ISCAG+P+R AF+EF+ R+ L
Sbjct: 660 TNVHYIRCIKPNTEKEAWKFDNLMVLSQLRACGVLETIKISCAGFPSRWAFEEFIQRYYL 719
Query: 683 LAP--------EVLDGSSEEVTA-CKRIL--KNVWLEGYQIGKTKVFLRAGQMAELDTRR 731
LAP ++ S E++ A C IL K + YQIGKTK+F +AG +A L+ R
Sbjct: 720 LAPTDQWGRVTADMEMSLEDMVAFCDLILSEKIDSKDKYQIGKTKIFFKAGVLAYLEKIR 779
Query: 732 SEILGKSASIIQRKVRSYLARQSFILLRVSALQIQAACRGQLARQVFEGMRREASSLLIQ 791
S+ + + A +IQ+ +R+ R ++ +S Q+ RG +RQ + + ++ L+Q
Sbjct: 780 SDKVTELAVLIQKHIRAKYYRSLYLQAMLSIKNCQSLIRGVQSRQRVDFEMKTDAATLLQ 839
Query: 792 RCLRMHIAKKAYKELYASAVSIQTGMRVMAAHCELHSRRRTSAAIIIQSHCRKYLALLNF 851
R + E + + +QT +R + + + +AI+IQS R +
Sbjct: 840 TLHRSTRVRSQVFETLKNILEVQTAIRRVLVSNFIQREFESRSAIMIQSKIRANSPKHRY 899
Query: 852 TKLKKAAIATQCAWRGKVARRELRKLKMAARETGALQDAKNKLEKQ----VEDLTLRLQL 907
LK I Q R K ++ +L++LK+ A +L+++ ++K+ +E+L ++
Sbjct: 900 QTLKTGTILIQALVRRKQSQEKLKQLKIQAESAASLKNSAAGIQKELIGFIEELISNIKE 959
Query: 908 EKRLRVDVEEAKAKENERLQSALQKMQLQFKETKVLLEKEREATKKLEARVPVIQEVPAV 967
+ + + + + + + TK +E+++ + + + ++++
Sbjct: 960 NDAKTTEYKSLLKHTSLPVVTGTNERTAAYISTKNQVEEDKVTIRTILTKYETLKDLCRK 1019
Query: 968 DHALLEKLS---SENEKLKTLVSSLE--------KKIDETEKRYEEEAKVSEERLKQALD 1016
+ LE L ++ + +L SSLE +I+ EK E + SE LK D
Sbjct: 1020 ELKSLESLEKGVNDEKFASSLQSSLELIKRDISDLRINAIEKDNERTSTSSE--LKDGTD 1077
Query: 1017 -AESKVIQMKTAMQ 1029
++ V+Q+ T Q
Sbjct: 1078 CTDNAVVQILTKRQ 1091
>MY52_SCHPO (O94477) Myosin 52 (Myosin type V-2)
Length = 1516
Score = 609 bits (1571), Expect = e-173
Identities = 395/1094 (36%), Positives = 597/1094 (54%), Gaps = 81/1094 (7%)
Query: 9 GTHVWIEDSDIAWIDGEVVGVNGEEIKVLCT-----SGKTVV-VKASKIYHKDTEVPP-- 60
G WI D WI G + E K T +TV+ VK + ++ P
Sbjct: 9 GLQCWIPDEQSQWIPGSIKDCRVEGEKAFLTVQDENENETVITVKPDDLNYEGRNGLPFL 68
Query: 61 ----SGVDDMTKLAYLHEPGVLNNLRSRYDINEIYTYTGNILIAVNPFIKLPHLYDIHMM 116
S DD+T L+YL+EP VL+ L +RY+ +IYTY+G +LIAVNPF +LP+LY ++
Sbjct: 69 RSINSDADDLTDLSYLNEPSVLDALSTRYNQLQIYTYSGIVLIAVNPFQRLPNLYTHEIV 128
Query: 117 AQYKGVAFGELSPHPFAVADAAYRLMINEGISQSILVSGESGAGKTETTKLLMRYLAYMG 176
Y + EL PH +A+A+ +Y+ M E +Q+I++SGESGAGKT + + +MRY A +
Sbjct: 129 RAYSEKSRDELDPHLYAIAEDSYKCMNQEHKNQTIIISGESGAGKTVSARYIMRYFASVQ 188
Query: 177 GRAAVAEGR--------TVEQKVLESNPVLEAFGNAKTVRNNNSSRFGKFVEIQFDQKGR 228
+ VE ++L +NP++EAFGN+KT RN+NSSRFGK+++I FD
Sbjct: 189 ALIQSTDSNFHEAPQLTAVENEILATNPIMEAFGNSKTSRNDNSSRFGKYIQILFDGNAT 248
Query: 229 ISGAAIRTYLLERSRVCQLSDPERNYHCFY-MLCAAPAEVVKKYKL-GHPRTFHYLNQSN 286
I GA I+TYLLERSR+ + ERNYH FY +L + +E ++K+KL + + F+YL Q N
Sbjct: 249 IIGAKIQTYLLERSRLVFQPNQERNYHIFYQILAGSSSEQLEKWKLVENSQEFNYLKQGN 308
Query: 287 CYELEGLDESKEYITIRRAMDVVGISIENQDAIFQVVAAILHLGNIEFVKGDEIDSSMPK 346
C +EG+++ +E+ A+ VGI + + IF ++AA+LH+GNIE VK D+ +
Sbjct: 309 CSTIEGVNDKEEFKATVDALKTVGIDNDTCECIFSLLAALLHIGNIE-VKHSRNDAYI-- 365
Query: 347 DEKSRFHLQTAAELFMCDANALEDSLCKRVIVTRDETITKWLDPEAAALSRDALAKIVYT 406
D K+ +L A L D ++L L KR I E I K L+ A ++RD++AK +Y
Sbjct: 366 DSKNE-NLINATSLLGVDPSSLVKWLTKRKIKMASEGILKPLNEFQAVVARDSVAKFLYA 424
Query: 407 RLFDWLVDTINNSI-----GQDPESKSLIGVLDIYGFESFKNNSFEQFCINLTNEKLQQH 461
LFDWLV TIN ++ + +KS IGVLDIYGFE FK NSFEQFCIN NEKLQQ
Sbjct: 425 SLFDWLVATINKALMYSADKSNQTAKSFIGVLDIYGFEHFKKNSFEQFCINYANEKLQQE 484
Query: 462 FNQHVFKMEQEEYKKEEIDWSYIEFVDNQDILDLIEKKPGGIISLLDEACMFPRSTHETF 521
F +HVFK+EQEEY E ++WSYI++ DNQ + +IE + GI+SLLDE C P ++ E +
Sbjct: 485 FYRHVFKLEQEEYAAEGLNWSYIDYQDNQQCISMIESRL-GILSLLDEECRMPTNSDENW 543
Query: 522 SQKLYQTFKD---HKRFSKPKLSPSDFTICHYAGDVTYQTEYFLDKNKDYVVAEHQSLLY 578
KL F + K + +FTI HYA DV Y E F+DKN+D + E L
Sbjct: 544 VSKLNDAFSKPEFKNSYQKSRFGNKEFTIKHYALDVVYCAEGFIDKNRDTISDELLELFT 603
Query: 579 ASTCPFVSGLF---------PPSPEETSKQSKFSSIGSRFKQQLQSLLETLSSTEPHYIR 629
S PFV L P ++ + K +++GS FK L SL+ T++ T HYIR
Sbjct: 604 NSDVPFVKDLVLFRLEQTAPPADTKKIKTKPKSNTLGSMFKSSLVSLMSTINETNAHYIR 663
Query: 630 CVKPNNLLKPAIFDNKNVLLQLRCGGVMEAIRISCAGYPTRKAFDEFVDRFGLLAPEVLD 689
C+KPN + FDN+ V+ QLR GV+E I+ISCAG+P+R FDEFV R+ +L P +
Sbjct: 664 CIKPNEEKEAWKFDNQMVVSQLRACGVLETIKISCAGFPSRWTFDEFVSRYYMLVPSAV- 722
Query: 690 GSSEEVTACKRIL-KNVWLEGYQIGKTKVFLRAGQMAELDTRRSEILGKSASIIQRKVRS 748
++E +T K IL K+ YQIGKTK+F R+G L++ R + L +A ++
Sbjct: 723 RTTESLTFSKAILEKHADPTKYQIGKTKIFFRSGVTPLLESARDKALKHAAHLLYEAFAV 782
Query: 749 YLARQSFILLRVSALQIQAACRGQLARQVFEGMRREASSLLIQRCLRMHIAKKAYKELYA 808
R F+L R QA G L+R+ E ++ + +Q R + +K + +
Sbjct: 783 NYYRTRFLLSRKRVRSFQAVAHGFLSRRHTEYELLSSNIIKLQSLWRTALKRKEFIQTKN 842
Query: 809 SAVSIQTGMRVMAAHCELHSRRRTSAAIIIQSHCRKYLALLNFTKLKKAAIATQCAWRGK 868
S + +Q+ +R L + + A +IIQS + A ++ +L+ A+ Q WR K
Sbjct: 843 SILKVQSIIRGFLLRQTLEEKTKHDATLIIQSLWLTFKAHKHYKELQYYAVRIQSLWRMK 902
Query: 869 VARRELRKLKMAARETGALQDAKNKLEKQVEDLTLRL---------------QLEKRLRV 913
+A+R+L +LK+ + + L+ +LE ++ +++ +L +LE L
Sbjct: 903 LAKRQLTELKIESTKASHLKQVSYRLESRLFEISKQLDNSEQENNKFRERIAELESHLSN 962
Query: 914 DVEEAKAKENERLQS-ALQKMQLQFKETKVLLEKEREA---------------TKKLEAR 957
E A+E E Q+ L Q Q E K LLE++ A T+ L
Sbjct: 963 YAEAKLAQERELEQTRVLISDQSQDGELKELLEEKENALIMMEEEMRQVNDANTELLRVN 1022
Query: 958 VPVIQEVPAVDHALLEKLSSENEKLKTLVSSLEKKIDETEKRYEEEAKVSEERLKQALDA 1017
+ ++ D ++E+ S EK + + S + E+++ SEE+ ++
Sbjct: 1023 ATLKSQLKNYDMIIVEQTSQLKEKNRIIASLTKATKILNSASSIEQSRNSEEKSRR---- 1078
Query: 1018 ESKVIQMKTAMQRL 1031
+S +++M+T + L
Sbjct: 1079 DSSLMEMRTQKEML 1092
>MYSN_ACACA (P05659) Myosin II heavy chain, non muscle
Length = 1509
Score = 608 bits (1567), Expect = e-173
Identities = 393/1124 (34%), Positives = 617/1124 (53%), Gaps = 80/1124 (7%)
Query: 15 EDSDIAWIDGEVVGVNGEEIKVLCTSGKTVVVKASKIYHKDTEVPP-SGVDDMTKLAYLH 73
+D+D A+ EV +G+ V +G+ ++ P GV+DM +L YL+
Sbjct: 42 KDADRAFCHVEVTKDDGKNFTVRLENGEEKSQPKNEKNFLGVNPPKFDGVEDMGELGYLN 101
Query: 74 EPGVLNNLRSRYDINEIYTYTGNILIAVNPFIKLPHLYDIHMMAQYKGVAFGELSPHPFA 133
EP VL+NL+ RYD + +TY+G L+ VNP+ +LP +Y ++ Y+G +++PH FA
Sbjct: 102 EPAVLHNLKKRYDADLFHTYSGLFLVVVNPYKRLP-VYTPEIIDIYRGRQRDKVAPHIFA 160
Query: 134 VADAAYRLMINEGISQSILVSGESGAGKTETTKLLMRYLAYMGGRAAVAEGRTVEQKVLE 193
++DAAYR M+N +QS+L++GESGAGKTE TK +++YL + GRA EG +EQ++LE
Sbjct: 161 ISDAAYRAMLNTRQNQSMLITGESGAGKTENTKKVIQYLTAIAGRA---EGGLLEQQLLE 217
Query: 194 SNPVLEAFGNAKTVRNNNSSRFGKFVEIQFDQKGRISGAAIRTYLLERSRVCQLSDPERN 253
NP+LEAFGNAKT +NNNSSRFGKF+E+QF+ G+I+GA YLLE+SRV ERN
Sbjct: 218 FNPILEAFGNAKTTKNNNSSRFGKFIELQFNAGGQITGANTFIYLLEKSRVTAQGAGERN 277
Query: 254 YHCFYMLC--AAPAEVVKKYKLGHPRTFHYLNQSNCYELEGLDESKEYITIRRAMDVVGI 311
+H FY + A P E+ +K KL P + +LNQ+ CY ++ +D++KE+ + +A D++ I
Sbjct: 278 FHIFYQILSKAMPEELKQKLKLTKPEDYFFLNQNACYTVDDMDDAKEFDHMLKAFDILNI 337
Query: 312 SIENQDAIFQVVAAILHLGNIEFVKGDEIDSSMPKDEKSRFHLQTAAELFMCDANALEDS 371
+ E + AIFQ ++AILHLGN+ F+ + + + K L AAEL A L+
Sbjct: 338 NEEERLAIFQTISAILHLGNLPFIDVNSETAGL----KDEVELNIAAELLGVSAAGLKAG 393
Query: 372 LCKRVIVTRDETITKWLDPEAAALSRDALAKIVYTRLFDWLVDTINNSIGQDPESKSLIG 431
L I +E +T+ L+ A SRDAL K ++ RLF W+V IN + ++ IG
Sbjct: 394 LLSPRIKAGNEWVTRALNKPKAMASRDALCKALFGRLFLWIVQKINRILSHKDKTALWIG 453
Query: 432 VLDIYGFESFKNNSFEQFCINLTNEKLQQHFNQHVFKMEQEEYKKEEIDWSYIEF-VDNQ 490
VLDI GFE F++NSFEQ CIN TNEKLQQ FN H+F +EQ+EY++E+IDW+++++ +D+Q
Sbjct: 454 VLDISGFEIFQHNSFEQLCINYTNEKLQQFFNHHMFTLEQQEYEREKIDWTFVDYGMDSQ 513
Query: 491 DILDLIEKKPGGIISLLDEACMFPRSTHETFSQKLYQTFKDHKRFSKPKLSPSDFTICHY 550
D +DLIEKKP GI+ LLDE +FP + +F++KL+QT ++H+ F +P+ ++F I HY
Sbjct: 514 DCIDLIEKKPMGILPLLDEQTVFPDADDTSFTKKLFQTHENHRNFRRPRFDANNFKIVHY 573
Query: 551 AGDVTYQTEYFLDKNKDYVVAEHQSLLYASTCPFVSGLF----------PPSPEETSKQ- 599
AG+V YQT +L+KN+D + + +L S+ FV+GLF P+ EE +
Sbjct: 574 AGEVEYQTSAWLEKNRDPLEDDLSNLCKKSSVRFVTGLFDEDLMPSFKAAPAEEEKAAAG 633
Query: 600 -------------SKFSSIGSRFKQQLQSLLETLSSTEPHYIRCVKPNNLLKPAIFDNKN 646
++F ++ ++K+QL L+ LSST PH+IRC+ PN KP + ++
Sbjct: 634 GSRNRSTGRGKGGAQFITVAFQYKEQLAHLMSMLSSTAPHFIRCIIPNLGKKPGVVSDQL 693
Query: 647 VLLQLRCGGVMEAIRISCAGYPTRKAFDEFVDRFGLLAPEVLDGSSEEVTACKRILKN-- 704
VL QL+C GV+E IRI+ G+P R +DEF+ R+ LL P S A K ++++
Sbjct: 694 VLDQLKCNGVLEGIRIARKGWPNRLKYDEFLKRYFLLKPGATPTSPSTKDAVKDLIEHLI 753
Query: 705 ------VWLEGYQIGKTKVFLRAGQMAELDTRRSEILGKSASIIQRKVRSYLARQSFILL 758
V + + G TK+F R+GQ+A ++ R + + K IQ R++LAR+ + +
Sbjct: 754 AKEPTKVNKDEVRFGVTKIFFRSGQLAAIEELREQAISKMVVSIQAGARAFLARRMYDKM 813
Query: 759 R---VSALQIQAACRG--QLARQVFEGMRREASSLLIQRCLRMHI--AKKAYKELYASAV 811
R VSA +Q R +L + + +A L+ QR + I KK K+L
Sbjct: 814 REQTVSAKILQRNIRAWLELKNWAWYQLYVKARPLISQRNFQKEIDDLKKQVKDLEKELA 873
Query: 812 SIQTGMRVMAAHCELHSRRRTSAAIIIQSHCRKYLALLNFTKLKKAAIATQCAWRGKVAR 871
+++ + +L A + + L +L+ K + KVA
Sbjct: 874 ALKDANAKLDKEKQL---AEEDADKLEKDLAALKLKILDLEGEKADLEEDNALLQKKVAG 930
Query: 872 RELRKLKMAARETGALQDAKNKLEKQVEDLTLRLQLEKRLRVDVEEAKAKENERLQSALQ 931
E +L+ + + + K KLE + +L L+ E+R R ++EAK K
Sbjct: 931 LE-EELQEETSASNDILEQKRKLEAEKGELKASLEEEERNRKALQEAKTKVESERNELQD 989
Query: 932 KMQLQFKETKVLLEKEREATKKLEARVPVIQEVPAVDHALLEKLSS--------ENE--- 980
K + + L +KE + +++L + + + L KL + NE
Sbjct: 990 KYEDEAAAHDSLKKKEEDLSRELRETKDALADAENISETLRSKLKNTERGADDVRNELDD 1049
Query: 981 ------KLKTLVSSLEKKIDETEKRYEEE------AKVSEERLKQAL-DAESKVIQMKTA 1027
+L+ SLE+++ +T + EEE A ++L Q L DA S+V +K+
Sbjct: 1050 VTATKLQLEKTKKSLEEELAQTRAQLEEEKSGKEAASSKAKQLGQQLEDARSEVDSLKSK 1109
Query: 1028 MQRLEEKFADIEFANHVLQKQSLSINSPVKTAVENLSTPVSEKL 1071
+ E+ + N L +Q L V+ V+ + KL
Sbjct: 1110 LSAAEKSLKTAKDQNRDLDEQ-LEDERTVRANVDKQKKALEAKL 1152
Score = 41.6 bits (96), Expect = 0.017
Identities = 50/241 (20%), Positives = 110/241 (44%), Gaps = 20/241 (8%)
Query: 880 AARETGALQDAKNKLEKQVEDLTLRLQLEKRLRVDVEEAKAKENERLQSALQKMQLQFKE 939
A R++GA Q + KL ++ +L L+ + A ++E +RL+ L++++ +E
Sbjct: 1217 AERDSGAQQ--RRKLNTRISELQSELENAPK----TGGASSEEVKRLEGELERLE---EE 1267
Query: 940 TKVLLEKEREATKKLEARVPVIQEV-PAVDHALLE--KLSSENEKLKTLVSSLEKKIDET 996
E A K L+ ++E+ D A + KL +N KLK + +++E
Sbjct: 1268 LLTAQEARAAAEKNLDKANLELEELRQEADDAARDNDKLVKDNRKLKADLDEARIQLEE- 1326
Query: 997 EKRYEEEAKVSEERLKQALDAESKVIQMKTAMQRLEEKFADIEFANHVLQKQSLSINSPV 1056
E++AK + + L AE + ++ + A + +++ A + AN+ + +SL +
Sbjct: 1327 ----EQDAKSHADSSSRRLLAEIEELKKRVAKETSDKQKAQDQKANYQRENESLKAD--- 1379
Query: 1057 KTAVENLSTPVSEKLENGHHVAEEPYDADTYVTPVKQFVAESDVKLKRSCSERHHGSFDS 1116
+ ++E + ++ + ++ K+ E++ +LK+ +R S +S
Sbjct: 1380 RDSIERRNRDAERQVRDLRAQLDDALSRLDSEKRAKEKSVEANRELKKVVLDRERQSLES 1439
Query: 1117 L 1117
L
Sbjct: 1440 L 1440
>MY51_SCHPO (O74805) Myosin 51 (Myosin type V-1)
Length = 1471
Score = 583 bits (1502), Expect = e-165
Identities = 378/1062 (35%), Positives = 568/1062 (52%), Gaps = 79/1062 (7%)
Query: 8 VGTHVWIEDSDIAWIDGEVVGV--NGEEIKVLCTSGKTVVVKASKIYHK-------DTEV 58
VG+ W+ +++ W ++ + NG KV+ T K+ V + Y + +E
Sbjct: 8 VGSECWVSNNNGHWDAARLIEIKDNGGG-KVVATVAKSSGVLETVNYQQLQNRNIGQSES 66
Query: 59 PPSGVDDMTKLAYLHEPGVLNNLRSRYDINEIYTYTGNILIAVNPFIKLPHLYDIHMMAQ 118
P D+T L YL+EP VL+ L +RY+ +IYTY+G +L+++NP+ LP Y+ +++
Sbjct: 67 P----SDLTNLPYLNEPSVLHALHNRYNNKQIYTYSGIVLVSINPYQNLPEFYNDNLIKH 122
Query: 119 YKGVAFGELSPHPFAVADAAYRLMINEGISQSILVSGESGAGKTETTKLLMRYLAYMGG- 177
+ PH +++A + Y + + +Q+I+VSGESGAGKT K +MRYL + G
Sbjct: 123 FHKDPEAAKVPHLYSIASSCYHALTTDSKNQTIIVSGESGAGKTVAAKYIMRYLTSVQGV 182
Query: 178 -RAAVAEGRTVEQKVLESNPVLEAFGNAKTVRNNNSSRFGKFVEIQFDQKGRISGAAIRT 236
V + R+VE +VL +NP++EAFGNAKT+RN+NSSRFGK+V I FD+ I+GA + T
Sbjct: 183 DHNGVVK-RSVENQVLATNPIMEAFGNAKTIRNDNSSRFGKYVTISFDENLLITGANVNT 241
Query: 237 YLLERSRVCQLSDPERNYHCFYMLCAAPAEVVK-KYKLGHPRTFHYLNQSNCYELEGLDE 295
YLLERSRV L ERNYH FY L E + K+ L +F+YL+Q NC E+ G+D+
Sbjct: 242 YLLERSRVVSLLKGERNYHIFYQLITGCTEEQRDKWFLESASSFNYLSQGNCDEISGVDD 301
Query: 296 SKEYITIRRAMDVVGISIENQDAIFQVVAAILHLGNIEFVKGDEIDSSMPKDEKSRFHLQ 355
S ++ RA+ +GIS Q+ +F ++AA+LHLGNIE P D +LQ
Sbjct: 302 SNDFTITCRALSTIGISESRQEDVFCLLAALLHLGNIEVCATRNEAQIQPGDG----YLQ 357
Query: 356 TAAELFMCDANALEDSLCKRVIVTRDETITKWLDPEAAALSRDALAKIVYTRLFDWLVDT 415
AA L D++ L + KR + TR ETI E A RD++AK +Y+ LF W+V
Sbjct: 358 KAALLLGVDSSTLAKWIVKRQLKTRSETIITSSTLEHAISIRDSVAKYLYSALFLWIVHM 417
Query: 416 INNSIGQDPESKSL---IGVLDIYGFESFKNNSFEQFCINLTNEKLQQHFNQHVFKMEQE 472
IN S+ + ++ IGV+DIYGFE F+ NS EQFCIN NEKLQQ FN+HVFK+EQE
Sbjct: 418 INASLDHNKVKRAAYKYIGVVDIYGFEHFEKNSMEQFCINYANEKLQQEFNKHVFKLEQE 477
Query: 473 EYKKEEIDWSYIEFVDNQDILDLIEKKPGGIISLLDEACMFPRSTHETFSQKLYQTF--K 530
EY KE +DW IE+ DNQ + LIE K GI+SLLDE C P H++F QKL K
Sbjct: 478 EYVKEGLDWRLIEYSDNQGCISLIEDKL-GILSLLDEECRLPSGNHQSFLQKLNNQLPTK 536
Query: 531 DHKRFSKPKLSPSDFTICHYAGDVTYQTEYFLDKNKDYVVAEHQSLLYASTCPFVSGLFP 590
+ + K + + F + HYA DV+YQ FL KN D + E SLL S F++ L
Sbjct: 537 HSQFYKKSRFNDGSFMVKHYALDVSYQVHDFLAKNSDAIPDEFISLLQNSKNEFITYLLD 596
Query: 591 PSPEETSKQ---------SKFSSIGSRFKQQLQSLLETLSSTEPHYIRCVKPNNLLKPAI 641
+ S Q S+ ++ S FK L L+ T+SST HYIRC+KPN P
Sbjct: 597 FYMQLVSSQNKNPRKTAISRKPTLSSMFKSSLSQLMTTVSSTNVHYIRCIKPNEEKLPWT 656
Query: 642 FDNKNVLLQLRCGGVMEAIRISCAGYPTRKAFDEFVDRFGLLAPEVLDGSSEEVTACKRI 701
F VL QLR GV E IRIS G+P R +++EF RF +L S E K++
Sbjct: 657 FSPPMVLSQLRACGVFETIRISSLGFPARFSYEEFAHRF-----RILLSSKEWEEDNKKL 711
Query: 702 LKNVWLE-------GYQIGKTKVFLRAGQMAELDTRRSEILGKSASIIQRKVRSYLARQS 754
N+ +Q+G++K+F R+ + + KS ++Q +R + R+
Sbjct: 712 TLNIVNSVIPHDNLNFQVGRSKIFFRSNVIGNFEEAHRATCSKSTVLLQSAIRGFFTRKE 771
Query: 755 FILLRVSALQIQAACRGQLARQVFEGMRREASSLLIQRCLRMHIAKKAYKELYASAVSIQ 814
+ +++Q+ G L RQ FE + E +++LIQ R +I +K Y L A+ IQ
Sbjct: 772 YQRTVKFIIKLQSVIMGWLTRQRFEREKIERAAILIQAHWRSYIQRKRYLSLIKCAIVIQ 831
Query: 815 TGMRVMAAHCELHSRRRTSAAIIIQSHCRKYLALLNFTKLKKAAIATQCAWRGKVARREL 874
+ +R A+ + R S+A ++ R Y A F LKK+ IA QC R + RR L
Sbjct: 832 SIVRKNIAYSRYINELRESSATLLAKFWRAYNARKTFRGLKKSVIALQCVSRSVLTRRYL 891
Query: 875 RKLKMAARETGALQDAKNKLEKQVEDLTLRLQLEKRLRVDVEEAKAKENERLQSALQKMQ 934
R+L+ +A T L + + L+ + +++ +L ++ +K+ L++ L +
Sbjct: 892 RRLQDSAGRTSILYEKQKNLQASITEVSKQL-----------KSNSKKVTVLRNKLNILN 940
Query: 935 LQFKETKVLLEKEREATKKLEARVPVIQEVPAVDHALLEKLSSENEKLKTLVSSLEKKID 994
+ K L++K + ++ PV + + D L++ L +E+ K+
Sbjct: 941 NSLSKWKCLIKKPSDFSE------PVSMDFTSNDEQLVQLLQAES------------KLR 982
Query: 995 ETEKRYEEEAKVSEERLKQALDAESKVIQMKTAMQ-RLEEKF 1035
+ ++ AK SE Q+ A + A+Q + EKF
Sbjct: 983 QASQQLYMAAKKSELGFVQSQTARENLSNYYQALQMTVSEKF 1024
>MY7A_MOUSE (P97479) Myosin VIIa
Length = 2215
Score = 558 bits (1437), Expect = e-158
Identities = 362/974 (37%), Positives = 532/974 (54%), Gaps = 81/974 (8%)
Query: 12 VWIEDSDIAWID---GEVVGVNGEEIKVLCTSGKTVVVKASKIYH-----KDTEVPPS-- 61
V ++ D W+D G+ V + LC SG+ VV H T + P
Sbjct: 2 VILQKGDYVWMDLKSGQEFDVPIGAVVKLCDSGQIQVVDDEDNEHWISPQNATHIKPMHP 61
Query: 62 ----GVDDMTKLAYLHEPGVLNNLRSRYDINEIYTYTGNILIAVNPFIKLPHLYDIHMMA 117
GV+DM +L L+E G+L N RY + IYTYTG+IL+AVNP+ +L +Y +
Sbjct: 62 TSVHGVEDMIRLGDLNEAGILRNRLIRYRDHLIYTYTGSILVAVNPY-QLLSIYSPEHIR 120
Query: 118 QYKGVAFGELSPHPFAVADAAYRLMINEGISQSILVSGESGAGKTETTKLLMRYLAYMGG 177
QY GE+ PH FA+AD Y M Q ++SGESGAGKTE+TKL++++LA + G
Sbjct: 121 QYTNKKIGEMPPHIFAIADNCYFNMKRNNRDQCCIISGESGAGKTESTKLILQFLAAISG 180
Query: 178 RAAVAEGRTVEQKVLESNPVLEAFGNAKTVRNNNSSRFGKFVEIQFDQKGRISGAAIRTY 237
+ + +EQ+VLE+ P+LEAFGNAKT+RN+NSSRFGK+++I F+++G I GA I Y
Sbjct: 181 QHS-----WIEQQVLEATPILEAFGNAKTIRNDNSSRFGKYIDIHFNKRGAIEGAKIEQY 235
Query: 238 LLERSRVCQLSDPERNYHCFY-MLCAAPAEVVKKYKLGHPRTFHYLNQSNCYELEGLDES 296
LL +SRVC+ + ERNYH FY ML E KK LG ++YL NC EG +S
Sbjct: 236 LLSKSRVCRQAPDERNYHVFYCMLEGMNEEEKKKLGLGQAADYNYLAMGNCITCEGRVDS 295
Query: 297 KEYITIRRAMDVVGISIENQDAIFQVVAAILHLGNIEFVKG--DEIDSSMPKDEKSRFHL 354
+EY IR AM V+ + I +++AAILH+GN+++ + +D+ S L
Sbjct: 296 QEYANIRSAMKVLMFTDTENWEISKLLAAILHMGNLQYEARTFENLDACEVLFSPS---L 352
Query: 355 QTAAELFMCDANALEDSLCKRVIVTRDETITKWLDPEAAALSRDALAKIVYTRLFDWLVD 414
TAA L + L L R ++TR ET++ L E A RDA K +Y RLF W+V+
Sbjct: 353 ATAASLLEVNPPDLMSCLTSRTLITRGETVSTPLSREQALDVRDAFVKGIYGRLFVWIVE 412
Query: 415 TINNSIGQDP-----ESKSLIGVLDIYGFESFKNNSFEQFCINLTNEKLQQHFNQHVFKM 469
IN +I + P S+ IG+LDI+GFE+F NSFEQ CIN NE LQQ F +HVFK+
Sbjct: 413 KINAAIYKPPPLEVKNSRRSIGLLDIFGFENFTVNSFEQLCINFANEHLQQFFVRHVFKL 472
Query: 470 EQEEYKKEEIDWSYIEFVDNQDILDLIEKKPGGIISLLDEACMFPRSTHETFSQKLYQTF 529
EQEEY E IDW +IEF DNQ+ LD+I +P +ISL+DE FP+ T T KL
Sbjct: 473 EQEEYDLESIDWLHIEFTDNQEALDMIANRPMNVISLIDEESKFPKGTDATMLHKLNSQH 532
Query: 530 KDHKRFSKPKLS-PSDFTICHYAGDVTYQTEYFLDKNKDYVVAEHQSLLYASTCPFVSGL 588
K + + PK S + F I H+AG V Y+++ FL+KN+D + + L+++S FV +
Sbjct: 533 KLNANYVPPKNSHETQFGINHFAGVVYYESQGFLEKNRDTLHGDIIQLVHSSRNKFVKQI 592
Query: 589 FPPS---PEETSKQSKFSSIGSRFKQQLQSLLETLSSTEPHYIRCVKPNNLLKPAIFDNK 645
F ET K+S ++ S+FK+ L+ L+ TL + +P ++RC+KPN KP +FD
Sbjct: 593 FQADVAMGAETRKRS--PTLSSQFKRSLELLMRTLGACQPFFVRCIKPNEFKKPMLFDRH 650
Query: 646 NVLLQLRCGGVMEAIRISCAGYPTRKAFDEFVDRFGLLAPEVLDG--SSEEVTACKRILK 703
+ QLR G+ME IRI AGYP R +F EF +R+ +L P V + C+R+ +
Sbjct: 651 LCVRQLRYSGMMETIRIRHAGYPIRYSFVEFGERYRVLLPGVKPAYKQGDLRGTCQRMAE 710
Query: 704 NV--WLEGYQIGKTKVFLRAGQMAELDTRRSEILGKSASIIQRKVRSYLARQSFILLRVS 761
V + +QIGKTK+FL+ L+ R + + ++Q+ +R + R +F+ L+ +
Sbjct: 711 AVLGTHDDWQIGKTKIFLKDHHDMLLEVERDKAITDRVILLQKVIRGFKDRSNFLRLKSA 770
Query: 762 ALQIQAACRGQLARQVFEGMRREASSLLIQRCLRMHIAKKAYKELYASAVSIQTGMRVMA 821
A IQ RG R+ +E +R L R +H ++K +K+
Sbjct: 771 ATLIQRHWRGHHCRKNYELIR-----LGFLRLQALHRSRKLHKQY--------------- 810
Query: 822 AHCELHSRRRTSAAIIIQSHCRKYLALLNFTKLKKAAIATQCAWRGKVARRELRKLKMAA 881
R I Q+ CR YL F A I Q RG +ARR R+L++
Sbjct: 811 -------RLARQRIIEFQARCRAYLVRKAFRHRLWAVITVQAYARGMIARRLHRRLRV-- 861
Query: 882 RETGALQDAKNKLEKQVEDLTLRLQLEKRLRVDVEEAKAKENERLQSALQKMQLQFKETK 941
+ ++++E +RL E++LR ++ KAKE + + QL ++ +
Sbjct: 862 -----------EYQRRLEAERMRLAEEEKLRKEMSAKKAKEEAERKHQERLAQLAREDAE 910
Query: 942 VLLEKEREATKKLE 955
L+++ EA +K E
Sbjct: 911 RELKEKEEARRKKE 924
>MY7A_HUMAN (Q13402) Myosin VIIa
Length = 2215
Score = 558 bits (1437), Expect = e-158
Identities = 373/990 (37%), Positives = 536/990 (53%), Gaps = 80/990 (8%)
Query: 12 VWIEDSDIAWID---GEVVGVNGEEIKVLCTSGKTVVVKASKIYH-----KDTEVPPS-- 61
V ++ D W+D G+ V + LC SG+ VV H T + P
Sbjct: 2 VILQQGDHVWMDLRLGQEFDVPIGAVVKLCDSGQVQVVDDEDNEHWISPQNATHIKPMHP 61
Query: 62 ----GVDDMTKLAYLHEPGVLNNLRSRYDINEIYTYTGNILIAVNPFIKLPHLYDIHMMA 117
GV+DM +L L+E G+L NL RY + IYTYTG+IL+AVNP+ +L +Y +
Sbjct: 62 TSVHGVEDMIRLGDLNEAGILRNLLIRYRDHLIYTYTGSILVAVNPY-QLLSIYSPEHIR 120
Query: 118 QYKGVAFGELSPHPFAVADAAYRLMINEGISQSILVSGESGAGKTETTKLLMRYLAYMGG 177
QY GE+ PH FA+AD Y M Q ++SGESGAGKTE+TKL++++LA + G
Sbjct: 121 QYTNKKIGEMPPHIFAIADNCYFNMKRNSRDQCCIISGESGAGKTESTKLILQFLAAISG 180
Query: 178 RAAVAEGRTVEQKVLESNPVLEAFGNAKTVRNNNSSRFGKFVEIQFDQKGRISGAAIRTY 237
+ + +EQ+VLE+ P+LEAFGNAKT+RN+NSSRFGK+++I F+++G I GA I Y
Sbjct: 181 QHS-----WIEQQVLEATPILEAFGNAKTIRNDNSSRFGKYIDIHFNKRGAIEGAKIEQY 235
Query: 238 LLERSRVCQLSDPERNYHCFY-MLCAAPAEVVKKYKLGHPRTFHYLNQSNCYELEGLDES 296
LLE+SRVC+ + ERNYH FY ML + KK LG ++YL NC EG +S
Sbjct: 236 LLEKSRVCRQALDERNYHVFYCMLEGMSEDQKKKLGLGQASDYNYLAMGNCITCEGRVDS 295
Query: 297 KEYITIRRAMDVVGISIENQDAIFQVVAAILHLGNIEFVKG--DEIDSSMPKDEKSRFHL 354
+EY IR AM V+ + I +++AAILHLGN+++ + +D+ S L
Sbjct: 296 QEYANIRSAMKVLMFTDTENWEISKLLAAILHLGNLQYEARTFENLDACEVLFSPS---L 352
Query: 355 QTAAELFMCDANALEDSLCKRVIVTRDETITKWLDPEAAALSRDALAKIVYTRLFDWLVD 414
TAA L + L L R ++TR ET++ L E A RDA K +Y RLF W+VD
Sbjct: 353 ATAASLLEVNPPDLMSCLTSRTLITRGETVSTPLSREQALDVRDAFVKGIYGRLFVWIVD 412
Query: 415 TINNSIGQDPE-----SKSLIGVLDIYGFESFKNNSFEQFCINLTNEKLQQHFNQHVFKM 469
IN +I + P S+ IG+LDI+GFE+F NSFEQ CIN NE LQQ F +HVFK+
Sbjct: 413 KINAAIYKPPSQDVKNSRRSIGLLDIFGFENFAVNSFEQLCINFANEHLQQFFVRHVFKL 472
Query: 470 EQEEYKKEEIDWSYIEFVDNQDILDLIEKKPGGIISLLDEACMFPRSTHETFSQKLYQTF 529
EQEEY E IDW +IEF DNQD LD+I KP IISL+DE FP+ T T KL
Sbjct: 473 EQEEYDLESIDWLHIEFTDNQDALDMIANKPMNIISLIDEESKFPKGTDTTMLHKLNSQH 532
Query: 530 KDHKRFSKPKLS-PSDFTICHYAGDVTYQTEYFLDKNKDYVVAEHQSLLYASTCPFVSGL 588
K + + PK + + F I H+AG V Y+T+ FL+KN+D + + L+++S F+ +
Sbjct: 533 KLNANYIPPKNNHETQFGINHFAGIVYYETQGFLEKNRDTLHGDIIQLVHSSRNKFIKQI 592
Query: 589 FPPS---PEETSKQSKFSSIGSRFKQQLQSLLETLSSTEPHYIRCVKPNNLLKPAIFDNK 645
F ET K+S ++ S+FK+ L+ L+ TL + +P ++RC+KPN KP +FD
Sbjct: 593 FQADVAMGAETRKRS--PTLSSQFKRSLELLMRTLGACQPFFVRCIKPNEFKKPMLFDRH 650
Query: 646 NVLLQLRCGGVMEAIRISCAGYPTRKAFDEFVDRFGLLAPEVLDG--SSEEVTACKRILK 703
+ QLR G+ME IRI AGYP R +F EFV+R+ +L P V + C+R+ +
Sbjct: 651 LCVRQLRYSGMMETIRIRRAGYPIRYSFVEFVERYRVLLPGVKPAYKQGDLRGTCQRMAE 710
Query: 704 NV--WLEGYQIGKTKVFLRAGQMAELDTRRSEILGKSASIIQRKVRSYLARQSFILLRVS 761
V + +QIGKTK+FL+ L+ R + + ++Q+ +R + R +F+ L+ +
Sbjct: 711 AVLGTHDDWQIGKTKIFLKDHHDMLLEVERDKAITDRVILLQKVIRGFKDRSNFLKLKNA 770
Query: 762 ALQIQAACRGQLARQVFEGMRREASSLLIQRCLRMHIAKKAYKELYASAVSIQTGMRVMA 821
A IQ RG R+ + MR L R +H ++K
Sbjct: 771 ATLIQRHWRGHNCRKNYGLMR-----LGFLRLQALHRSRK-------------------- 805
Query: 822 AHCELHSRRRTSAAIII--QSHCRKYLALLNFTKLKKAAIATQCAWRGKVARRELRKLKM 879
LH + R + II Q+ CR YL F A + Q RG +ARR ++L+
Sbjct: 806 ----LHQQYRLARQRIIQFQARCRAYLVRKAFRHRLWAVLTVQAYARGMIARRLHQRLR- 860
Query: 880 AARETGALQDAKNKLEKQVEDLTLRLQLEKRLRVDVEEAKAKENERL-QSALQKMQLQFK 938
A L+ K +L ++ +L+ E + EEA+ K ERL Q A + + + K
Sbjct: 861 -AEYLWRLEAEKMRLAEEE-----KLRKEMSAKKAKEEAERKHQERLAQLAREDAERELK 914
Query: 939 ETKVLLEKEREATKKLEARVPVIQEVPAVD 968
E + K+ + AR + VD
Sbjct: 915 EKEAARRKKELLEQMERARHEPVNHSDMVD 944
Database: sprot
Posted date: Nov 25, 2004 10:54 AM
Number of letters in database: 59,974,054
Number of sequences in database: 164,201
Lambda K H
0.318 0.133 0.380
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 167,624,848
Number of Sequences: 164201
Number of extensions: 7128313
Number of successful extensions: 33836
Number of sequences better than 10.0: 1063
Number of HSP's better than 10.0 without gapping: 261
Number of HSP's successfully gapped in prelim test: 825
Number of HSP's that attempted gapping in prelim test: 26531
Number of HSP's gapped (non-prelim): 4256
length of query: 1497
length of database: 59,974,054
effective HSP length: 123
effective length of query: 1374
effective length of database: 39,777,331
effective search space: 54654052794
effective search space used: 54654052794
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 73 (32.7 bits)
Medicago: description of AC133341.11