BLAST2 result
BLASTP 2.2.2 [Dec-14-2001]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= AC131455.7 + phase: 0 /pseudo
(859 letters)
Database: sprot
164,201 sequences; 59,974,054 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
AGOL_ARATH (Q9SJK3) Argonaute-like protein At2g27880 458 e-128
PINH_ARATH (Q9XGW1) PINHEAD protein (ZWILLE protein) 440 e-123
AGO1_ARATH (O04379) Argonaute protein 432 e-120
I2C4_HUMAN (Q9HCK5) Eukaryotic translation initiation factor 2C ... 348 5e-95
I2C2_RABIT (O77503) Eukaryotic translation initiation factor 2C ... 342 3e-93
I2C2_RAT (Q9QZ81) Eukaryotic translation initiation factor 2C 2 ... 340 7e-93
I2C2_MOUSE (Q8CJG0) Eukaryotic translation initiation factor 2C ... 340 1e-92
I2C4_MOUSE (Q8CJF8) Eukaryotic translation initiation factor 2C ... 337 6e-92
I2C1_HUMAN (Q9UL18) Eukaryotic translation initiation factor 2C ... 336 1e-91
I2C2_HUMAN (Q9UKV8) Eukaryotic translation initiation factor 2C ... 336 2e-91
I2C1_MOUSE (Q8CJG1) Eukaryotic translation initiation factor 2C ... 332 2e-90
I2C3_MOUSE (Q8CJF9) Eukaryotic translation initiation factor 2C ... 330 1e-89
I2C3_HUMAN (Q9H9G7) Eukaryotic translation initiation factor 2C ... 327 1e-88
AGO1_SCHPO (O74957) Cell cycle control protein ago1 (RNA interfe... 306 2e-82
YO43_CAEEL (P34681) Hypothetical protein ZK757.3 in chromosome III 252 3e-66
AGO2_DROME (Q9VUQ5) Argonaute 2 protein 244 7e-64
PIWI_BRARE (Q8UVX0) Piwi protein 143 2e-33
PIWI_DROME (Q9VKM1) Piwi protein 125 5e-28
GCC7_CAEEL (Q21770) Germ cell expressed protein R06C7.1 101 1e-20
YQ53_CAEEL (Q09249) Hypothetical protein C16C10.3 in chromosome III 95 9e-19
>AGOL_ARATH (Q9SJK3) Argonaute-like protein At2g27880
Length = 997
Score = 458 bits (1179), Expect = e-128
Identities = 302/835 (36%), Positives = 451/835 (53%), Gaps = 83/835 (9%)
Query: 43 RRGLGTKGAKLPLLTNHFEVNVANTNRVFFQYSVALFYEDGRPVEGKGAGRKIIDKVQET 102
R G GT G K+ + NHF V VA+ R + Y V++ E V K R ++ + +
Sbjct: 150 RPGRGTLGKKVMVRANHFLVQVAD--RDLYHYDVSINPE----VISKTVNRNVMKLLVKN 203
Query: 103 Y-DSELNGKDLAYDG-ETLFTIGSLAQKKLEFIVVVEDVASNRNNANTSPDKKRIRKSYR 160
Y DS L GK AYDG ++L+T G L EF+V ++A R + ++ D+
Sbjct: 204 YKDSHLGGKSPAYDGRKSLYTAGPLPFDSKEFVV---NLAEKRADGSSGKDRP------- 253
Query: 161 SKTYKVEINFAKEIPLQAIANALKGHEAENYQEAIRVLDIILRQHSAKQGCLLVRQNFFH 220
+KV + L + L + E + I+VLD++LR + + V ++FFH
Sbjct: 254 ---FKVAVKNVTSTDLYQLQQFLDRKQREAPYDTIQVLDVVLRDKPSND-YVSVGRSFFH 309
Query: 221 ND-----PNNLNDVGGGVLSCKGLHSSFRTTQSGLSLNIDVSTTMIVRPGPVVDFLIENQ 275
+ ++G G+ +G S R TQ GLSLNIDVS P V DF+ +
Sbjct: 310 TSLGKDARDGRGELGDGIEYWRGYFQSLRLTQMGLSLNIDVSARSFYEPIVVTDFISKFL 369
Query: 276 NVRD---PF-SLDWNKAKRTLKNLRITAKPSN--QEYKITGLSELSCKDQLFTMKKRGAV 329
N+RD P D K K+ L+ L++ N + KI+G+S L ++ FT+
Sbjct: 370 NIRDLNRPLRDSDRLKVKKVLRTLKVKLLHWNCTKSAKISGISSLPIRELRFTL------ 423
Query: 330 AGEDDTEEITVYDYFVHRRKIDLQYSAGLPCINVGKPKRPTYIPIELCSLISLQRYTKAL 389
+D E TV YF + ++Y A LP I G RP Y+P+ELC + QRYTK L
Sbjct: 424 ---EDKSEKTVVQYFAEKYNYRVKYQA-LPAIQTGSDTRPVYLPMELCQIDEGQRYTKRL 479
Query: 390 STSQRSSLVEKSRQKPVERMRVLSNALKASNYGSEPMLRNCGISITSEFTQVDGRVLQAP 449
+ Q ++L++ + Q+P +R + N + +NY + + + G+S+T++ ++ RVL P
Sbjct: 480 NEKQVTALLKATCQRPPDRENSIKNLVVKNNYNDD-LSKEFGMSVTTQLASIEARVLPPP 538
Query: 450 RLKF---GNEDF-NPRNGRWNFNNKKFVEPVSLGNWSVVNFSARCDVRGLVRDLIKCGGM 505
LK+ G E NPR G+WN +KK V + +W+ V+FS R D RGL ++ C +
Sbjct: 539 MLKYHDSGKEKMVNPRLGQWNMIDKKMVNGAKVTSWTCVSFSTRID-RGLPQEF--CKQL 595
Query: 506 KGILVEQPKDVIEENRQFKGEP-------PVFRVEKMFADVLKLSKRPSFLLCLLPERKN 558
G+ V + +FK +P P +E+ D+ K + L+ +LP+
Sbjct: 596 IGMCVSK-------GMEFKPQPAIPFISCPPEHIEEALLDIHKRAPGLQLLIVILPDVTG 648
Query: 559 SDLYGPWKKKNLAEFGIVTQCIAPTRVND---QYLTNVLLKINAKLGGMNSWLGVEHSRS 615
S YG K+ E GIV+QC P +VN QY+ NV LKIN K GG N+ L R+
Sbjct: 649 S--YGKIKRICETELGIVSQCCQPRQVNKLNKQYMENVALKINVKTGGRNTVLNDAIRRN 706
Query: 616 IPIVSKVPTLILGMDVSHGSPGQPDIPSIAAVVSSRKWPLISKYRACVRTQGSKVEMIDN 675
IP+++ PT+I+G DV+H PG+ PSIAAVV+S WP I+KYR V Q + E+I +
Sbjct: 707 IPLITDRPTIIMGADVTHPQPGEDSSPSIAAVVASMDWPEINKYRGLVSAQAHREEIIQD 766
Query: 676 LFKPVSDKE----DEGIIRELLLDFFHSSEERRPENIIIFRDGVSESQFNEVLNVELSQI 731
L+K V D + G+IRE + F ++ + P+ II +RDGVSE QF++VL E++ I
Sbjct: 767 LYKLVQDPQRGLVHSGLIREHFIAFRRATGQI-PQRIIFYRDGVSEGQFSQVLLHEMTAI 825
Query: 732 IEACKFLDENWNPKFMVIVAQKNHHTKFFQPRSPD--------NVPPGTVVDSKICHPRN 783
+AC L EN+ P+ ++ QK HHT+ F + + N+ PGTVVD+KICHP
Sbjct: 826 RKACNSLQENYVPRVTFVIVQKRHHTRLFPEQHGNRDMTDKSGNIQPGTVVDTKICHPNE 885
Query: 784 YDFYMCAHAGMIGTSRPTHYHVLLDEIGFSPDDLQELVHSLSYVYQRSTTAISVV 838
+DFY+ +HAG+ GTSRP HYHVLLDE GF+ D LQ L ++L Y Y R T ++S+V
Sbjct: 886 FDFYLNSHAGIQGTSRPAHYHVLLDENGFTADQLQMLTNNLCYTYARCTKSVSIV 940
>PINH_ARATH (Q9XGW1) PINHEAD protein (ZWILLE protein)
Length = 988
Score = 440 bits (1131), Expect = e-123
Identities = 292/840 (34%), Positives = 444/840 (52%), Gaps = 86/840 (10%)
Query: 43 RRGLGTKGAKLPLLTNHFEVNVANTNRVFFQYSVALFYEDGRPVEGKGAGRKIIDKVQET 102
R G GT G K + NHF ++ + QY V + E V K R II ++
Sbjct: 131 RPGFGTLGTKCIVKANHFLADLPTKD--LNQYDVTITPE----VSSKSVNRAIIAELVRL 184
Query: 103 Y-DSELNGKDLAYDG-ETLFTIGSLAQKKLEFIVVVEDVASNRNNANTSPDKKRIRKSYR 160
Y +S+L + AYDG ++L+T G L EF V + D D I R
Sbjct: 185 YKESDLGRRLPAYDGRKSLYTAGELPFTWKEFSVKIVD-----------EDDGIINGPKR 233
Query: 161 SKTYKVEINFAKEIPLQAIANALKGHEAENYQEAIRVLDIILRQHSAKQGCLLVRQNFFH 220
++YKV I F + + L G A+ QEA+++LDI+LR+ S K+ C + R +FF
Sbjct: 234 ERSYKVAIKFVARANMHHLGEFLAGKRADCPQEAVQILDIVLRELSVKRFCPVGR-SFFS 292
Query: 221 NDPNNLNDVGGGVLSCKGLHSSFRTTQSGLSLNIDVSTTMIVRPGPVVDF---LIENQNV 277
D +G G+ S G + S R TQ GLSLNID+++ + P PV++F L+ +
Sbjct: 293 PDIKTPQRLGEGLESWCGFYQSIRPTQMGLSLNIDMASAAFIEPLPVIEFVAQLLGKDVL 352
Query: 278 RDPFS-LDWNKAKRTLKNLRITAKPS---NQEYKITGLSELSCKDQLFTMKKRGAVAGED 333
P S D K K+ L+ +++ ++Y++ GL+ ++ +F + ++
Sbjct: 353 SKPLSDSDRVKIKKGLRGVKVEVTHRANVRRKYRVAGLTTQPTRELMFPV--------DE 404
Query: 334 DTEEITVYDYFVHRRKIDLQYSAGLPCINVGKPKRPTYIPIELCSLISLQRYTKALSTSQ 393
+ +V +YF +Q++ LPC+ VG K+ +Y+P+E C ++ QRYTK L+ Q
Sbjct: 405 NCTMKSVIEYFQEMYGFTIQHTH-LPCLQVGNQKKASYLPMEACKIVEGQRYTKRLNEKQ 463
Query: 394 RSSLVEKSRQKPVERMRVLSNALKASNYGSEPMLRNCGISITSEFTQVDGRVLQAPRLKF 453
++L++ + Q+P +R + ++ + Y +P + G++I+ + V+ R+L AP LK+
Sbjct: 464 ITALLKVTCQRPRDRENDILRTVQHNAYDQDPYAKEFGMNISEKLASVEARILPAPWLKY 523
Query: 454 ---GNE-DFNPRNGRWNFNNKKFVEPVSLGNWSVVNFSARCD---VRGLVRDLIKCGGMK 506
G E D P+ G+WN NKK + +++ W+ VNFS RG +L + +
Sbjct: 524 HENGKEKDCLPQVGQWNMMNKKMINGMTVSRWACVNFSRSVQENVARGFCNELGQMCEVS 583
Query: 507 GILVEQPKDVIEENRQFKGEP--PVF-----RVEKMFADVLKLS------KRPSFLLCLL 553
G+ +F EP P++ +VEK V S K LL +L
Sbjct: 584 GM-------------EFNPEPVIPIYSARPDQVEKALKHVYHTSMNKTKGKELELLLAIL 630
Query: 554 PERKNSDLYGPWKKKNLAEFGIVTQCIAPT---RVNDQYLTNVLLKINAKLGGMNSWLGV 610
P+ N LYG K+ E G+++QC +++ QYL NV LKIN K+GG N+ L
Sbjct: 631 PDN-NGSLYGDLKRICETELGLISQCCLTKHVFKISKQYLANVSLKINVKMGGRNTVLVD 689
Query: 611 EHSRSIPIVSKVPTLILGMDVSHGSPGQPDIPSIAAVVSSRKWPLISKYRACVRTQGSKV 670
S IP+VS +PT+I G DV+H G+ PSIAAVV+S+ WP ++KY V Q +
Sbjct: 690 AISCRIPLVSDIPTIIFGADVTHPENGEESSPSIAAVVASQDWPEVTKYAGLVCAQAHRQ 749
Query: 671 EMIDNLFK----PVSDKEDEGIIRELLLDFFHSSEERRPENIIIFRDGVSESQFNEVLNV 726
E+I +L+K PV G+IR+LL+ F + ++P II +RDGVSE QF +VL
Sbjct: 750 ELIQDLYKTWQDPVRGTVSGGMIRDLLISF-RKATGQKPLRIIFYRDGVSEGQFYQVLLY 808
Query: 727 ELSQIIEACKFLDENWNPKFMVIVAQKNHHTKFFQPRSPD--------NVPPGTVVDSKI 778
EL I +AC L+ N+ P IV QK HHT+ F D N+ PGTVVD+KI
Sbjct: 809 ELDAIRKACASLEPNYQPPVTFIVVQKRHHTRLFANNHRDKNSTDRSGNILPGTVVDTKI 868
Query: 779 CHPRNYDFYMCAHAGMIGTSRPTHYHVLLDEIGFSPDDLQELVHSLSYVYQRSTTAISVV 838
CHP +DFY+C+HAG+ GTSRP HYHVL DE F+ D +Q L ++L Y Y R T ++S+V
Sbjct: 869 CHPTEFDFYLCSHAGIQGTSRPAHYHVLWDENNFTADGIQSLTNNLCYTYARCTRSVSIV 928
>AGO1_ARATH (O04379) Argonaute protein
Length = 1048
Score = 432 bits (1112), Expect = e-120
Identities = 292/878 (33%), Positives = 453/878 (51%), Gaps = 93/878 (10%)
Query: 12 PPPPIVPPNVKPIKIEQ---EHLKKKLPT-----KAPMARRGLGTKGAKLPLLTNHFEVN 63
P P ++ + + +EQ + +P+ K PM R G G G + + NHF
Sbjct: 144 PEPTVLAQQFEQLSVEQGAPSQAIQPIPSSSKAFKFPM-RPGKGQSGKRCIVKANHFFAE 202
Query: 64 VANTNRVFFQYSVALFYEDGRPVEGKGAGRKIIDKVQETY-DSELNGKDLAYDG-ETLFT 121
+ + + Y V + E V +G R ++ ++ + Y DS L + AYDG ++L+T
Sbjct: 203 LPDKD--LHHYDVTITPE----VTSRGVNRAVMKQLVDNYRDSHLGSRLPAYDGRKSLYT 256
Query: 122 IGSLAQKKLEFIVVVEDVASNRNNANTSPDKKRIRKSYRSKTYKVEINFAKEIPLQAIAN 181
G L EF + + D R + +KV I L +
Sbjct: 257 AGPLPFNSKEFRINLLDEEVGAGGQR------------REREFKVVIKLVARADLHHLGM 304
Query: 182 ALKGHEAENYQEAIRVLDIILRQHSAKQGCLLVRQNFFHNDPNNLNDVGGGVLSCKGLHS 241
L+G +++ QEA++VLDI+LR+ + + V ++F+ D +G G+ S +G +
Sbjct: 305 FLEGKQSDAPQEALQVLDIVLRELPTSR-YIPVGRSFYSPDIGKKQSLGDGLESWRGFYQ 363
Query: 242 SFRTTQSGLSLNIDVSTTMIVRPGPVVDFLIENQNVRD----PFS-LDWNKAKRTLKNLR 296
S R TQ GLSLNID+S+T + PV+ F+ + N RD P S D K K+ L+ ++
Sbjct: 364 SIRPTQMGLSLNIDMSSTAFIEANPVIQFVCDLLN-RDISSRPLSDADRVKIKKALRGVK 422
Query: 297 ITAKPSN---QEYKITGLSELSCKDQLFTMKKRGAVAGEDDTEEITVYDYFVHRRKIDLQ 353
+ ++Y+I+GL+ ++ ++ F + +R + +V +YF +Q
Sbjct: 423 VEVTHRGNMRRKYRISGLTAVATRELTFPVDERNT--------QKSVVEYFHETYGFRIQ 474
Query: 354 YSAGLPCINVGKPKRPTYIPIELCSLISLQRYTKALSTSQRSSLVEKSRQKPVERMRVLS 413
++ LPC+ VG RP Y+P+E+C ++ QRY+K L+ Q ++L++ + Q+P++R + +
Sbjct: 475 HTQ-LPCLQVGNSNRPNYLPMEVCKIVEGQRYSKRLNERQITALLKVTCQRPIDREKDIL 533
Query: 414 NALKASNYGSEPMLRNCGISITSEFTQVDGRVLQAPRLKFGNEDFN----PRNGRWNFNN 469
++ ++Y + + GI I++ V+ R+L P LK+ P+ G+WN N
Sbjct: 534 QTVQLNDYAKDNYAQEFGIKISTSLASVEARILPPPWLKYHESGREGTCLPQVGQWNMMN 593
Query: 470 KKFVEPVSLGNWSVVNFSARCD---VRGLVRDLIKCGGMKGILVEQPKDVIEENRQFKGE 526
KK + ++ NW +NFS + R ++L + + G+ P+ V+
Sbjct: 594 KKMINGGTVNNWICINFSRQVQDNLARTFCQELAQMCYVSGMAFN-PEPVL--------- 643
Query: 527 PPVFRVEKMFADVLKL-----------SKRPSFLLCLLPERKNSDLYGPWKKKNLAEFGI 575
PPV + VLK K L+ +LP+ N LYG K+ E GI
Sbjct: 644 PPVSARPEQVEKVLKTRYHDATSKLSQGKEIDLLIVILPDN-NGSLYGDLKRICETELGI 702
Query: 576 VTQCIAPTRV---NDQYLTNVLLKINAKLGGMNSWLGVEHSRSIPIVSKVPTLILGMDVS 632
V+QC V + QY+ NV LKIN K+GG N+ L SR IP+VS PT+I G DV+
Sbjct: 703 VSQCCLTKHVFKMSKQYMANVALKINVKVGGRNTVLVDALSRRIPLVSDRPTIIFGADVT 762
Query: 633 HGSPGQPDIPSIAAVVSSRKWPLISKYRACVRTQGSKVEMIDNLFKPVSDKEDE----GI 688
H PG+ PSIAAVV+S+ WP I+KY V Q + E+I +LFK D + G+
Sbjct: 763 HPHPGEDSSPSIAAVVASQDWPEITKYAGLVCAQAHRQELIQDLFKEWKDPQKGVVTGGM 822
Query: 689 IRELLLDFFHSSEERRPENIIIFRDGVSESQFNEVLNVELSQIIEACKFLDENWNPKFMV 748
I+ELL+ F S+ + P II +RDGVSE QF +VL EL I +AC L+ + P
Sbjct: 823 IKELLIAFRRSTGHK-PLRIIFYRDGVSEGQFYQVLLYELDAIRKACASLEAGYQPPVTF 881
Query: 749 IVAQKNHHTKFFQPRSPD--------NVPPGTVVDSKICHPRNYDFYMCAHAGMIGTSRP 800
+V QK HHT+ F D N+ PGTVVDSKICHP +DFY+C+HAG+ GTSRP
Sbjct: 882 VVVQKRHHTRLFAQNHNDRHSVDRSGNILPGTVVDSKICHPTEFDFYLCSHAGIQGTSRP 941
Query: 801 THYHVLLDEIGFSPDDLQELVHSLSYVYQRSTTAISVV 838
HYHVL DE F+ D LQ L ++L Y Y R T ++S+V
Sbjct: 942 AHYHVLWDENNFTADGLQSLTNNLCYTYARCTRSVSIV 979
>I2C4_HUMAN (Q9HCK5) Eukaryotic translation initiation factor 2C 4
(eIF2C 4) (eIF-2C 4) (Argonaute 4)
Length = 861
Score = 348 bits (892), Expect = 5e-95
Identities = 257/833 (30%), Positives = 417/833 (49%), Gaps = 81/833 (9%)
Query: 40 PMARRGLGTKGAKLPLLTNHFEVNVANTNRVFFQYSVALFYEDGRPVEGKGAGRKIIDKV 99
P R GLGT G + LL NHF+V + + + Y V + E RP + R+++D +
Sbjct: 15 PPRRPGLGTVGKPIRLLANHFQVQIPKID--VYHYDVDIKPEK-RP---RRVNREVVDTM 68
Query: 100 QETYDSELNG-KDLAYDGE-TLFTIGSLAQKKLEFIVVVEDVASNRNNANTSPDKKRIRK 157
+ ++ G + YDG+ ++T L + +R + + +
Sbjct: 69 VRHFKMQIFGDRQPGYDGKRNMYTAHPL------------PIGRDRVDMEVT-----LPG 111
Query: 158 SYRSKTYKVEINFAKEIPLQAIANALKGHEAENYQEAIRVLDIILRQHSAKQGCLLVRQN 217
+ +T+KV + + + LQ + AL GH E ++++ LD+I R H V ++
Sbjct: 112 EGKDQTFKVSVQWVSVVSLQLLLEALAGHLNEVPDDSVQALDVITR-HLPSMRYTPVGRS 170
Query: 218 FFHNDPNNLNDVGGGVLSCKGLHSSFRTTQSGLSLNIDVSTTMIVRPGPVVDFL-----I 272
FF + +GGG G H S R + LNIDVS T R P+++F+ I
Sbjct: 171 FFSPPEGYYHPLGGGREVWFGFHQSVRPAMWNMMLNIDVSATAFYRAQPIIEFMCEVLDI 230
Query: 273 ENQNVRDPFSLDWNKAKRT--LKNLRITAKPSNQ---EYKITGLSELSCKDQLFTMKKRG 327
+N N + D + K T ++ L++ Q +Y++ ++ Q F ++
Sbjct: 231 QNINEQTKPLTDSQRVKFTKEIRGLKVEVTHCGQMKRKYRVCNVTRRPASHQTFPLQLEN 290
Query: 328 AVAGEDDTEEITVYDYFVHRRKIDLQYSAGLPCINVGKPKRPTYIPIELCSLISLQRYTK 387
A E TV YF + + L+Y LPC+ VG+ ++ TY+P+E+C++++ QR K
Sbjct: 291 GQA-----MECTVAQYFKQKYSLQLKY-PHLPCLQVGQEQKHTYLPLEVCNIVAGQRCIK 344
Query: 388 ALSTSQRSSLVEKSRQKPVERMRVLSNALKASNY--GSEPMLRNCGISITSEFTQVDGRV 445
L+ +Q S++++ + + +R +S +K+++ G +P L+ GI + +E T++ GRV
Sbjct: 345 KLTDNQTSTMIKATARSAPDRQEEISRLVKSNSMVGGPDPYLKEFGIVVHNEMTELTGRV 404
Query: 446 LQAPRLKFGNED---FNPRNGRWNFNNKKFVEPVSLGNWSVVNFSARCDVRGLVRDLIKC 502
L AP L++G + P G W+ K+F + + W+V F+ + R DL+K
Sbjct: 405 LPAPMLQYGGRNKTVATPNQGVWDMRGKQFYAGIEIKVWAVACFAPQKQCR---EDLLKS 461
Query: 503 GGMKGILVEQPKDVIEE-NRQFKGEPPVFR-------VEKMFADVLKLSKRPSFLLCLLP 554
+Q + + ++ +G+P + VE MF + ++ +LP
Sbjct: 462 ------FTDQLRKISKDAGMPIQGQPCFCKYAQGADSVEPMFKHLKMTYVGLQLIVVILP 515
Query: 555 ERKNSDLYGPWKKKNLAEFGIVTQCIAPTRV---NDQYLTNVLLKINAKLGGMNSWLGVE 611
+ + +Y K+ G+ TQC+ V + Q L+N+ LKINAKLGG+N+ L V
Sbjct: 516 GK--TPVYAEVKRVGDTLLGMATQCVQVKNVVKTSPQTLSNLCLKINAKLGGINNVL-VP 572
Query: 612 HSRSIPIVSKVPTLILGMDVSHGSPGQPDIPSIAAVVSSRKWPLISKYRACVRTQGSKVE 671
H R P V + P + LG DV+H G PSIAAVV S S+Y A VR Q S+ E
Sbjct: 573 HQR--PSVFQQPVIFLGADVTHPPAGDGKKPSIAAVVGSMDGH-PSRYCATVRVQTSRQE 629
Query: 672 MIDNLFKPVSDKED-EGIIRELLLDFFHSSEERRPENIIIFRDGVSESQFNEVLNVELSQ 730
+ L +D ++RELL+ F+ S+ +P II +R GVSE Q +V EL
Sbjct: 630 ISQELLYSQEVIQDLTNMVRELLIQFYKST-RFKPTRIIYYRGGVSEGQMKQVAWPELIA 688
Query: 731 IIEACKFLDENWNPKFMVIVAQKNHHTKFF------QPRSPDNVPPGTVVDSKICHPRNY 784
I +AC L+E++ P IV QK HHT+ F + NVP GT VDS I HP +
Sbjct: 689 IRKACISLEEDYRPGITYIVVQKRHHTRLFCADKTERVGKSGNVPAGTTVDSTITHPSEF 748
Query: 785 DFYMCAHAGMIGTSRPTHYHVLLDEIGFSPDDLQELVHSLSYVYQRSTTAISV 837
DFY+C+HAG+ GTSRP+HY VL D+ F+ D+LQ L + L + Y R T ++S+
Sbjct: 749 DFYLCSHAGIQGTSRPSHYQVLWDDNCFTADELQLLTYQLCHTYVRCTRSVSI 801
>I2C2_RABIT (O77503) Eukaryotic translation initiation factor 2C 2
(eIF2C 2) (eIF-2C 2) (Fragment)
Length = 840
Score = 342 bits (876), Expect = 3e-93
Identities = 249/831 (29%), Positives = 414/831 (48%), Gaps = 89/831 (10%)
Query: 40 PMARRGLGTKGAKLPLLTNHFEVNVANTNRVFFQYSVALFYEDGRPVE-GKGAGRKIIDK 98
P R GT G + L N FE+++ + ++ + +P + + R+I++
Sbjct: 6 PPPRPDFGTSGRTIKLQANFFEMDIPKIDIYHYELDI-------KPEKCPRRVNREIVEH 58
Query: 99 VQETYDSELNG-KDLAYDG-ETLFTIGSL--AQKKLEFIVVVEDVASNRNNANTSPDKKR 154
+ + + +++ G + +DG + L+T L ++K+E V + +R
Sbjct: 59 MVQHFKAQIFGDRKPVFDGRKNLYTAMPLPIGREKVELEVTLPGEGKDR----------- 107
Query: 155 IRKSYRSKTYKVEINFAKEIPLQAIANALKGHEAENYQEAIRVLDIILRQHSAKQGCLLV 214
+KV I + + LQA+ +AL G E I+ LD+++R H V
Sbjct: 108 --------IFKVSIKWVSCVSLQALHDALSGRLPSVPFETIQALDVVMR-HLPSMRYTPV 158
Query: 215 RQNFFHNDPNNLNDVGGGVLSCKGLHSSFRTTQSGLSLNIDVSTTMIVRPGPVVDFLIEN 274
++FF N +GGG G H S R + + LNIDVS T + PV++F+ E
Sbjct: 159 GRSFFTASEGCSNPLGGGREVWFGFHQSVRPSLWKMMLNIDVSATAFYKAQPVIEFVCEV 218
Query: 275 QNVRD------PFSLDWNKAKRT--LKNLRITAKPSNQ---EYKITGLSELSCKDQLFTM 323
+ + P + D + K T +K L++ Q +Y++ ++ Q F +
Sbjct: 219 LDFKSIEEQQKPLT-DSQRVKFTKEIKGLKVEITHCGQMKRKYRVCNVTRRPASHQTFPL 277
Query: 324 KKRGAVAGEDDTEEITVYDYFVHRRKIDLQYSAGLPCINVGKPKRPTYIPIELCSLISLQ 383
++ T E TV YF R K+ L+Y LPC+ VG+ ++ TY+P+E+C++++ Q
Sbjct: 278 QQESG-----QTVECTVAQYFKDRHKLVLRYPH-LPCLQVGQEQKHTYLPLEVCNIVAGQ 331
Query: 384 RYTKALSTSQRSSLVEKSRQKPVERMRVLSNALKASNYGSEPMLRNCGISITSEFTQVDG 443
R K L+ +Q S+++ + + +R +S ++++++ ++P +R GI + E T V G
Sbjct: 332 RCIKKLTDNQTSTMIRATARSAPDRQEEISKLMRSASFNTDPYVREFGIMVKDEMTDVTG 391
Query: 444 RVLQAPRLKFGNED---FNPRNGRWNFNNKKFVEPVSLGNWSVVNFSAR-----CDVRGL 495
RVLQ P + +G + P G W+ NK+F + + W++ F+ + ++
Sbjct: 392 RVLQPPSILYGGRNKAIATPVQGVWDMRNKQFHTGIEIKVWAIACFAPQRQCTEVHLKSF 451
Query: 496 VRDLIKCGGMKGILVEQPKDVIEENRQFKGEPPVFRVEKMFADVLKLSKRPSFLLCLLPE 555
L K G+ ++ + + P+FR K L+L ++ +LP
Sbjct: 452 TEQLRKISRDAGMPIQGQPCFCKYAQGADSVGPMFRHLKNTYAGLQL------VVVILPG 505
Query: 556 RKNSDLYGPWKKKNLAEFGIVTQCIAPT---RVNDQYLTNVLLKINAKLGGMNSWLGVEH 612
+ + +Y K+ G+ TQC+ R Q L+N+ LKIN KLGG+N+ L
Sbjct: 506 K--TPVYAEVKRVGDTVLGMATQCVQMKNVQRTTPQTLSNLCLKINVKLGGVNNIL---L 560
Query: 613 SRSIPIVSKVPTLILGMDVSHGSPGQPDIPSIAAVVSSRKWPLISKYRACVRTQGSKVEM 672
+ P V + P + LG DV+H G PSIAAVV S ++Y A VR Q + E+
Sbjct: 561 PQGRPPVFQQPVIFLGADVTHPPAGDGKKPSIAAVVGSMD-AHPNRYCATVRVQQHRQEI 619
Query: 673 IDNLFKPVSDKEDEGIIRELLLDFFHSSEERRPENIIIFRDGVSESQFNEVLNVELSQII 732
I +L ++RELL+ F+ S+ + P II +RDGVSE QF +VL+ EL I
Sbjct: 620 IQDL---------AAMVRELLIQFYKSTRFK-PTRIIFYRDGVSEGQFQQVLHHELLAIR 669
Query: 733 EACKFLDENWNPKFMVIVAQKNHHTKFF------QPRSPDNVPPGTVVDSKICHPRNYDF 786
EAC L++++ P IV QK HHT+ F + N+P GT VD+KI HP +DF
Sbjct: 670 EACIKLEKDYQPGITFIVVQKRHHTRLFCTDKNERVGKSGNIPAGTTVDTKITHPTEFDF 729
Query: 787 YMCAHAGMIGTSRPTHYHVLLDEIGFSPDDLQELVHSLSYVYQRSTTAISV 837
Y+C+HAG+ GTSRP+HYHVL D+ FS D+LQ L + L + Y R T ++S+
Sbjct: 730 YLCSHAGIQGTSRPSHYHVLWDDNRFSSDELQILTYQLCHTYVRCTRSVSI 780
>I2C2_RAT (Q9QZ81) Eukaryotic translation initiation factor 2C 2
(eIF2C 2) (eIF-2C 2) (Golgi ER protein 95 kDa) (GERp95)
Length = 860
Score = 340 bits (873), Expect = 7e-93
Identities = 249/831 (29%), Positives = 412/831 (48%), Gaps = 89/831 (10%)
Query: 40 PMARRGLGTKGAKLPLLTNHFEVNVANTNRVFFQYSVALFYEDGRPVE-GKGAGRKIIDK 98
P R GT G + L N FE+++ + ++ + +P + + R+I++
Sbjct: 26 PPPRPDFGTTGRTIKLQANFFEMDIPKIDIYHYELDI-------KPEKCPRRVNREIVEH 78
Query: 99 VQETYDSELNG-KDLAYDG-ETLFTIGSL--AQKKLEFIVVVEDVASNRNNANTSPDKKR 154
+ + + +++ G + +DG + L+T L + K+E V + +R
Sbjct: 79 MVQHFKTQIFGDRKPVFDGRKNLYTAMPLPIGRDKVELEVTLPGEGKDR----------- 127
Query: 155 IRKSYRSKTYKVEINFAKEIPLQAIANALKGHEAENYQEAIRVLDIILRQHSAKQGCLLV 214
+KV I + + LQA+ +AL G E I+ LD+++R H V
Sbjct: 128 --------IFKVSIKWVSCVSLQALHDALSGRLPSVPFETIQALDVVMR-HLPSMRYTPV 178
Query: 215 RQNFFHNDPNNLNDVGGGVLSCKGLHSSFRTTQSGLSLNIDVSTTMIVRPGPVVDFLIEN 274
++FF N +GGG G H S R + + LNIDVS T + PV++F+ E
Sbjct: 179 GRSFFTASEGCSNPLGGGREVWFGFHQSVRPSLWKMMLNIDVSATAFYKAQPVIEFVCEV 238
Query: 275 QNVRD------PFSLDWNKAKRT--LKNLRITAKPSNQ---EYKITGLSELSCKDQLFTM 323
+ + P + D + K T +K L++ Q +Y++ ++ Q F +
Sbjct: 239 LDFKSIEEQQKPLT-DSQRVKFTKEIKGLKVEITHCGQMKRKYRVCNVTRRPASHQTFPL 297
Query: 324 KKRGAVAGEDDTEEITVYDYFVHRRKIDLQYSAGLPCINVGKPKRPTYIPIELCSLISLQ 383
++ T E TV YF R K+ L+Y LPC+ VG+ ++ TY+P+E+C++++ Q
Sbjct: 298 QQESG-----QTVECTVAQYFKDRHKLVLRYPH-LPCLQVGQEQKHTYLPLEVCNIVAGQ 351
Query: 384 RYTKALSTSQRSSLVEKSRQKPVERMRVLSNALKASNYGSEPMLRNCGISITSEFTQVDG 443
R K L+ +Q S+++ + + +R +S ++++++ ++P +R GI + E T V G
Sbjct: 352 RCIKKLTDNQTSTMIRATARSAPDRQEEISKLMRSASFNTDPYVREFGIMVKDEMTDVTG 411
Query: 444 RVLQAPRLKFGNED---FNPRNGRWNFNNKKFVEPVSLGNWSVVNFSAR-----CDVRGL 495
RVLQ P + +G + P G W+ NK+F + + W++ F+ + ++
Sbjct: 412 RVLQPPSILYGGRNKAIATPVQGVWDMRNKQFHTGIEIKVWAIACFAPQRQCTEVHLKSF 471
Query: 496 VRDLIKCGGMKGILVEQPKDVIEENRQFKGEPPVFRVEKMFADVLKLSKRPSFLLCLLPE 555
L K G+ ++ + + P+FR K L+L ++ +LP
Sbjct: 472 TEQLRKISRDAGMPIQGQPCFCKYAQGADSVEPMFRHLKNTYAGLQL------VVVILPG 525
Query: 556 RKNSDLYGPWKKKNLAEFGIVTQCIAPT---RVNDQYLTNVLLKINAKLGGMNSWLGVEH 612
+ + +Y K+ G+ TQC+ R Q L+N+ LKIN KLGG+N+ L
Sbjct: 526 K--TPVYAEVKRVGDTVLGMATQCVQMKNVQRTTPQTLSNLCLKINVKLGGVNNIL---L 580
Query: 613 SRSIPIVSKVPTLILGMDVSHGSPGQPDIPSIAAVVSSRKWPLISKYRACVRTQGSKVEM 672
+ P V + P + LG DV+H G PSIAAVV S ++Y A VR Q + E+
Sbjct: 581 PQGRPPVFQQPVIFLGADVTHPPAGDGKKPSIAAVVGSMD-AHPNRYCATVRVQQHRQEI 639
Query: 673 IDNLFKPVSDKEDEGIIRELLLDFFHSSEERRPENIIIFRDGVSESQFNEVLNVELSQII 732
I +L ++RELL+ F+ S+ + P II +RDGVSE QF +VL+ EL I
Sbjct: 640 IQDL---------AAMVRELLIQFYKSTRFK-PTRIIFYRDGVSEGQFQQVLHHELLAIR 689
Query: 733 EACKFLDENWNPKFMVIVAQKNHHTKFF------QPRSPDNVPPGTVVDSKICHPRNYDF 786
EAC L++ + P IV QK HHT+ F + N+P GT VD+KI HP +DF
Sbjct: 690 EACIKLEKEYQPGITFIVVQKRHHTRLFCTDKNERVGKSGNIPAGTTVDTKITHPTEFDF 749
Query: 787 YMCAHAGMIGTSRPTHYHVLLDEIGFSPDDLQELVHSLSYVYQRSTTAISV 837
Y+C+HAG+ GTSRP+HYHVL D+ FS D+LQ L + L + Y R T ++S+
Sbjct: 750 YLCSHAGIQGTSRPSHYHVLWDDNRFSSDELQILTYQLCHTYVRCTRSVSI 800
>I2C2_MOUSE (Q8CJG0) Eukaryotic translation initiation factor 2C 2
(eIF2C 2) (eIF-2C 2) (Piwi/argonaute family protain
meIF2C2)
Length = 860
Score = 340 bits (871), Expect = 1e-92
Identities = 249/830 (30%), Positives = 410/830 (49%), Gaps = 87/830 (10%)
Query: 40 PMARRGLGTKGAKLPLLTNHFEVNVANTNRVFFQYSVALFYEDGRPVEGKGAGRKIIDKV 99
P R GT G + L N FE+++ + ++ + + RP + R+I++ +
Sbjct: 26 PPPRPDFGTTGRTIKLQANFFEMDIPKIDIYHYELDIK---PEKRP---RRVNREIVEHM 79
Query: 100 QETYDSELNG-KDLAYDG-ETLFTIGSL--AQKKLEFIVVVEDVASNRNNANTSPDKKRI 155
+ + +++ G + +DG + L+T L + K+E V + +R
Sbjct: 80 VQHFKTQIFGDRKPVFDGRKNLYTAMPLPIGRDKVELEVTLPGEGKDR------------ 127
Query: 156 RKSYRSKTYKVEINFAKEIPLQAIANALKGHEAENYQEAIRVLDIILRQHSAKQGCLLVR 215
KV I + + LQA+ +AL G E I+ LD+++R H V
Sbjct: 128 -------ILKVSIKWVSCVSLQALHDALSGRLPSVPFETIQALDVVMR-HLPSMRYTPVG 179
Query: 216 QNFFHNDPNNLNDVGGGVLSCKGLHSSFRTTQSGLSLNIDVSTTMIVRPGPVVDFLIENQ 275
++FF N +GGG G H S R + + LNIDVS T + PV++F+ E
Sbjct: 180 RSFFTASEGCSNPLGGGREVWFGFHQSVRPSLWKMMLNIDVSATAFYKAQPVIEFVCEVL 239
Query: 276 NVRD------PFSLDWNKAKRT--LKNLRITAKPSNQ---EYKITGLSELSCKDQLFTMK 324
+ + P + D + K T +K L++ Q +Y++ ++ Q F ++
Sbjct: 240 DFKSIEEQQKPLT-DSQRVKFTKEIKGLKVEITHCGQMKRKYRVCNVTRRPASHQTFPLQ 298
Query: 325 KRGAVAGEDDTEEITVYDYFVHRRKIDLQYSAGLPCINVGKPKRPTYIPIELCSLISLQR 384
+ T E TV YF R K+ L+Y LPC+ VG+ ++ TY+P+E+C++++ QR
Sbjct: 299 QESG-----QTVECTVAQYFKDRHKLVLRYPH-LPCLQVGQEQKHTYLPLEVCNIVAGQR 352
Query: 385 YTKALSTSQRSSLVEKSRQKPVERMRVLSNALKASNYGSEPMLRNCGISITSEFTQVDGR 444
K L+ Q S+++ + + +R +S ++++++ ++P +R GI + E T V GR
Sbjct: 353 CIKKLTDDQTSTMIRATARSAPDRQEEISKLMRSASFNTDPYVREFGIMVKDEMTDVTGR 412
Query: 445 VLQAPRLKFGNED---FNPRNGRWNFNNKKFVEPVSLGNWSVVNFSAR-----CDVRGLV 496
VLQ P + +G + P G W+ NK+F + + W++ F+ + ++
Sbjct: 413 VLQPPSILYGGRNKAIATPVQGVWDMRNKQFHTGIEIKVWAIACFAPQRQCTEVHLKSFT 472
Query: 497 RDLIKCGGMKGILVEQPKDVIEENRQFKGEPPVFRVEKMFADVLKLSKRPSFLLCLLPER 556
L K G+ ++ + + P+FR K L+L ++ +LP +
Sbjct: 473 EQLRKISRDAGMPIQGQPCFCKYAQGADSVEPMFRHLKNTYAGLQL------VVVILPGK 526
Query: 557 KNSDLYGPWKKKNLAEFGIVTQCIAPT---RVNDQYLTNVLLKINAKLGGMNSWLGVEHS 613
+ +Y K+ G+ TQC+ R Q L+N+ LKIN KLGG+N+ L
Sbjct: 527 --TPVYAEVKRVGDTVLGMATQCVQMKNVQRTTPQTLSNLCLKINVKLGGVNNIL---LP 581
Query: 614 RSIPIVSKVPTLILGMDVSHGSPGQPDIPSIAAVVSSRKWPLISKYRACVRTQGSKVEMI 673
+ P V + P + LG DV+H G PSIAAVV S ++Y A VR Q + E+I
Sbjct: 582 QGRPPVFQQPVIFLGADVTHPPAGDGKKPSIAAVVGSMD-AHPNRYCATVRVQQHRQEII 640
Query: 674 DNLFKPVSDKEDEGIIRELLLDFFHSSEERRPENIIIFRDGVSESQFNEVLNVELSQIIE 733
+L ++RELL+ F+ S+ + P II +RDGVSE QF +VL+ EL I E
Sbjct: 641 QDL---------AAMVRELLIQFYKSTRFK-PTRIIFYRDGVSEGQFQQVLHHELLAIRE 690
Query: 734 ACKFLDENWNPKFMVIVAQKNHHTKFF------QPRSPDNVPPGTVVDSKICHPRNYDFY 787
AC L++++ P IV QK HHT+ F + N+P GT VD+KI HP +DFY
Sbjct: 691 ACIKLEKDYQPGITFIVVQKRHHTRLFCTDKNERVGKSGNIPAGTTVDTKITHPTEFDFY 750
Query: 788 MCAHAGMIGTSRPTHYHVLLDEIGFSPDDLQELVHSLSYVYQRSTTAISV 837
+C+HAG+ GT RP+HYHVL D+ FS D+LQ L + L + Y R T ++S+
Sbjct: 751 LCSHAGIQGTGRPSHYHVLWDDNRFSSDELQILTYQLCHTYVRCTRSVSI 800
>I2C4_MOUSE (Q8CJF8) Eukaryotic translation initiation factor 2C 4
(eIF2C 4) (eIF-2C 4) (Piwi/argonaute family protain
meIF2C4)
Length = 861
Score = 337 bits (865), Expect = 6e-92
Identities = 254/833 (30%), Positives = 414/833 (49%), Gaps = 81/833 (9%)
Query: 40 PMARRGLGTKGAKLPLLTNHFEVNVANTNRVFFQYSVALFYEDGRPVEGKGAGRKIIDKV 99
P R GLGT G + LL NHF+V + + + Y V + E RP + R+++D +
Sbjct: 15 PPRRPGLGTVGKPIRLLANHFQVQIPKID--VYHYDVDIKPEK-RP---RRVNREVVDTM 68
Query: 100 QETYDSELNG-KDLAYDGE-TLFTIGSLAQKKLEFIVVVEDVASNRNNANTSPDKKRIRK 157
+ ++ G + YDG+ ++T L + + V T P + +
Sbjct: 69 VRHFKMQIFGDRQPGYDGKRNMYTAHPLPIGRDRIDMEV-----------TLPGEGK--- 114
Query: 158 SYRSKTYKVEINFAKEIPLQAIANALKGHEAENYQEAIRVLDIILRQHSAKQGCLLVRQN 217
+T+KV + + LQ + AL GH E ++++ LD+I R H V ++
Sbjct: 115 ---DQTFKVSVQWVSVASLQLLLEALAGHLNEVPDDSVQALDVITR-HLPSMRYTPVGRS 170
Query: 218 FFHNDPNNLNDVGGGVLSCKGLHSSFRTTQSGLSLNIDVSTTMIVRPGPVVDFL-----I 272
FF + +GGG G H S R + LNIDVS T R P+++F+ I
Sbjct: 171 FFSPPEGYYHPLGGGREVWFGFHQSVRPAMWNMMLNIDVSATAFYRAQPIIEFMCEVLDI 230
Query: 273 ENQNVRDPFSLDWNKAKRT--LKNLRITAKPSNQ---EYKITGLSELSCKDQLFTMKKRG 327
+N N + D + K T ++ L++ Q +Y++ ++ Q F ++
Sbjct: 231 QNINEQTKPLTDSQRVKFTKEIRGLKVEVTHCGQMKRKYRVCNVTRRPASHQTFPLQLEN 290
Query: 328 AVAGEDDTEEITVYDYFVHRRKIDLQYSAGLPCINVGKPKRPTYIPIELCSLISLQRYTK 387
A E TV YF + + L++ LPC+ VG+ ++ TY+P+E+C++++ QR K
Sbjct: 291 GQA-----MECTVAQYFKQKYSLQLKHPH-LPCLQVGQEQKHTYLPLEVCNIVAGQRCIK 344
Query: 388 ALSTSQRSSLVEKSRQKPVERMRVLSNALKASNY--GSEPMLRNCGISITSEFTQVDGRV 445
L+ +Q S++++ + + +R +S +K+++ G +P L+ GI + +E T++ GRV
Sbjct: 345 KLTDNQTSTMIKATARSAPDRQEEISRLVKSNSMVGGPDPYLKEFGIVVHNEMTELTGRV 404
Query: 446 LQAPRLKFGNED---FNPRNGRWNFNNKKFVEPVSLGNWSVVNFSARCDVRGLVRDLIKC 502
L AP L++G + P G W+ K+F + + W+V F+ + R DL+K
Sbjct: 405 LPAPMLQYGGRNKTVATPSQGVWDMRGKQFYAGIEIKVWAVACFAPQKQCR---EDLLKS 461
Query: 503 GGMKGILVEQPKDVIEE-NRQFKGEPPVFR-------VEKMFADVLKLSKRPSFLLCLLP 554
+Q + + ++ +G+P + VE MF + ++ +LP
Sbjct: 462 ------FTDQLRKISKDAGMPIQGQPCFCKYAQGADSVEPMFKHLKMTYVGLQLIVVILP 515
Query: 555 ERKNSDLYGPWKKKNLAEFGIVTQCIAPTRV---NDQYLTNVLLKINAKLGGMNSWLGVE 611
+ + +Y K+ G+ TQC+ V + Q L+N+ LK+NAKLGG+N+ + V
Sbjct: 516 GK--TPVYAEVKRVGDTLLGMATQCVQIKNVVKTSPQTLSNLCLKMNAKLGGINN-VPVP 572
Query: 612 HSRSIPIVSKVPTLILGMDVSHGSPGQPDIPSIAAVVSSRKWPLISKYRACVRTQGSKVE 671
H R P V + P + LG DV+H G PSIAAVV S S+Y A V Q S+ E
Sbjct: 573 HQR--PSVFQQPVIFLGADVTHPPAGDGKKPSIAAVVGSMDGHP-SRYCATVWVQTSRQE 629
Query: 672 MIDNLFKPVSDKED-EGIIRELLLDFFHSSEERRPENIIIFRDGVSESQFNEVLNVELSQ 730
+ L +D + RELL+ F+ S+ + P II +R GVSE Q +V EL
Sbjct: 630 IAQELLYSQEVVQDLTSMARELLIQFYKSTRFK-PTRIIYYRGGVSEGQMKQVAWPELIA 688
Query: 731 IIEACKFLDENWNPKFMVIVAQKNHHTKFF------QPRSPDNVPPGTVVDSKICHPRNY 784
I +AC L+E++ P IV QK HHT+ F + NVP GT VDS + HP +
Sbjct: 689 IRKACISLEEDYRPGITYIVVQKRHHTRLFCADKMERVGKSGNVPAGTTVDSTVTHPSEF 748
Query: 785 DFYMCAHAGMIGTSRPTHYHVLLDEIGFSPDDLQELVHSLSYVYQRSTTAISV 837
DFY+C+HAG+ GTSRP+HY VL D+ F+ D+LQ L + L + Y R T ++S+
Sbjct: 749 DFYLCSHAGIQGTSRPSHYQVLWDDNCFTADELQLLTYQLCHTYVRCTRSVSI 801
>I2C1_HUMAN (Q9UL18) Eukaryotic translation initiation factor 2C 1
(eIF2C 1) (eIF-2C 1) (Putative RNA-binding protein Q99)
Length = 857
Score = 336 bits (862), Expect = 1e-91
Identities = 240/828 (28%), Positives = 412/828 (48%), Gaps = 89/828 (10%)
Query: 43 RRGLGTKGAKLPLLTNHFEVNVANTNRVFFQYSVALFYEDGRPVEGKGAGRKIIDKVQET 102
R G+GT G + LL N+FEV++ + ++ + D P + R++++ + +
Sbjct: 26 RPGIGTVGKPIKLLANYFEVDIPKIDVYHYEVDIK---PDKCP---RRVNREVVEYMVQH 79
Query: 103 YDSELNG-KDLAYDGE-TLFTIGSL--AQKKLEFIVVVEDVASNRNNANTSPDKKRIRKS 158
+ ++ G + YDG+ ++T+ +L ++++F V + +R
Sbjct: 80 FKPQIFGDRKPVYDGKKNIYTVTALPIGNERVDFEVTIPGEGKDR--------------- 124
Query: 159 YRSKTYKVEINFAKEIPLQAIANALKGHEAENYQEAIRVLDIILRQHSAKQGCLLVRQNF 218
+KV I + + + + AL + E+++ LD+ +R H A V ++F
Sbjct: 125 ----IFKVSIKWLAIVSWRMLHEALVSGQIPVPLESVQALDVAMR-HLASMRYTPVGRSF 179
Query: 219 FHNDPNNLNDVGGGVLSCKGLHSSFRTTQSGLSLNIDVSTTMIVRPGPVVDFLIENQNVR 278
F + +GGG G H S R + LNIDVS T + PV++F+ E ++R
Sbjct: 180 FSPPEGYYHPLGGGREVWFGFHQSVRPAMWKMMLNIDVSATAFYKAQPVIEFMCEVLDIR 239
Query: 279 D----PFSLDWNKAKR---TLKNLRITAKPSNQ---EYKITGLSELSCKDQLFTMKKRGA 328
+ P L ++ R +K L++ Q +Y++ ++ Q F ++
Sbjct: 240 NINEQPKPLTDSQRVRFTKEIKGLKVEVTHCGQMKRKYRVCNVTRRPASHQTFPLQLESG 299
Query: 329 VAGEDDTEEITVYDYFVHRRKIDLQYSAGLPCINVGKPKRPTYIPIELCSLISLQRYTKA 388
T E TV YF + + L+Y LPC+ VG+ ++ TY+P+E+C++++ QR K
Sbjct: 300 -----QTVECTVAQYFKQKYNLQLKYPH-LPCLQVGQEQKHTYLPLEVCNIVAGQRCIKK 353
Query: 389 LSTSQRSSLVEKSRQKPVERMRVLSNALKASNYGSEPMLRNCGISITSEFTQVDGRVLQA 448
L+ +Q S++++ + + +R +S +K ++Y +P ++ GI + + T+V GRVL A
Sbjct: 354 LTDNQTSTMIKATARSAPDRQEEISRLMKNASYNLDPYIQEFGIKVKDDMTEVTGRVLPA 413
Query: 449 PRLKFGNED---FNPRNGRWNFNNKKFVEPVSLGNWSVVNFSARCDVRGLVRDLIKCGGM 505
P L++G + P G W+ K+F + + W++ F+ + R V +
Sbjct: 414 PILQYGGRNRAIATPNQGVWDMRGKQFYNGIEIKVWAIACFAPQKQCREEV--------L 465
Query: 506 KGILVEQPKDVIEENRQFKGEPPVFR-------VEKMFADVLKLSKRPSFLLCLLPERKN 558
K + K + +G+P + VE MF + ++ +LP +
Sbjct: 466 KNFTDQLRKISKDAGMPIQGQPCFCKYAQGADSVEPMFRHLKNTYSGLQLIIVILPGK-- 523
Query: 559 SDLYGPWKKKNLAEFGIVTQCIAPTRV---NDQYLTNVLLKINAKLGGMNSWLGVEHSRS 615
+ +Y K+ G+ TQC+ V + Q L+N+ LKIN KLGG+N+ L V H RS
Sbjct: 524 TPVYAEVKRVGDTLLGMATQCVQVKNVVKTSPQTLSNLCLKINVKLGGINNIL-VPHQRS 582
Query: 616 IPIVSKVPTLILGMDVSHGSPGQPDIPSIAAVVSSRKWPLISKYRACVRTQGSKVEMIDN 675
V + P + LG DV+H G PSI AVV S S+Y A VR Q + E+I++
Sbjct: 583 A--VFQQPVIFLGADVTHPPAGDGKKPSITAVVGSMD-AHPSRYCATVRVQRPRQEIIED 639
Query: 676 LFKPVSDKEDEGIIRELLLDFFHSSEERRPENIIIFRDGVSESQFNEVLNVELSQIIEAC 735
L ++RELL+ F+ S+ + P II +RDGV E Q ++L+ EL I +AC
Sbjct: 640 L---------SYMVRELLIQFYKSTRFK-PTRIIFYRDGVPEGQLPQILHYELLAIRDAC 689
Query: 736 KFLDENWNPKFMVIVAQKNHHTKFFQPRSPD------NVPPGTVVDSKICHPRNYDFYMC 789
L++++ P IV QK HHT+ F + N+P GT VD+ I HP +DFY+C
Sbjct: 690 IKLEKDYQPGITYIVVQKRHHTRLFCADKNERIGKSGNIPAGTTVDTNITHPFEFDFYLC 749
Query: 790 AHAGMIGTSRPTHYHVLLDEIGFSPDDLQELVHSLSYVYQRSTTAISV 837
+HAG+ GTSRP+HY+VL D+ F+ D+LQ L + L + Y R T ++S+
Sbjct: 750 SHAGIQGTSRPSHYYVLWDDNRFTADELQILTYQLCHTYVRCTRSVSI 797
>I2C2_HUMAN (Q9UKV8) Eukaryotic translation initiation factor 2C 2
(eIF2C 2) (eIF-2C 2)
Length = 851
Score = 336 bits (861), Expect = 2e-91
Identities = 227/706 (32%), Positives = 365/706 (51%), Gaps = 58/706 (8%)
Query: 160 RSKTYKVEINFAKEIPLQAIANALKGHEAENYQEAIRVLDIILRQHSAKQGCLLVRQNFF 219
+ + +KV I + + LQA+ +AL G E I+ LD+++R H V ++FF
Sbjct: 116 KDRIFKVSIKWVSCVSLQALHDALSGRLPSVPFETIQALDVVMR-HLPSMRYTPVGRSFF 174
Query: 220 HNDPNNLNDVGGGVLSCKGLHSSFRTTQSGLSLNIDVSTTMIVRPGPVVDFLIENQNVRD 279
N +GGG G H S R + + LNIDVS T + PV++F+ E + +
Sbjct: 175 TASEGCSNPLGGGREVWFGFHQSVRPSLWKMMLNIDVSATAFYKAQPVIEFVCEVLDFKS 234
Query: 280 ------PFSLDWNKAKRT--LKNLRITAKPSNQ---EYKITGLSELSCKDQLFTMKKRGA 328
P + D + K T +K L++ Q +Y++ ++ Q F +++
Sbjct: 235 IEEQQKPLT-DSQRVKFTKEIKGLKVEITHCGQMKRKYRVCNVTRRPASHQTFPLQQESG 293
Query: 329 VAGEDDTEEITVYDYFVHRRKIDLQYSAGLPCINVGKPKRPTYIPIELCSLISLQRYTKA 388
T E TV YF R K+ L+Y LPC+ VG+ ++ TY+P+E+C++++ QR K
Sbjct: 294 -----QTVECTVAQYFKDRHKLVLRYPH-LPCLQVGQEQKHTYLPLEVCNIVAGQRCIKK 347
Query: 389 LSTSQRSSLVEKSRQKPVERMRVLSNALKASNYGSEPMLRNCGISITSEFTQVDGRVLQA 448
L+ +Q S+++ + + +R +S ++++++ ++P +R GI + E T V GRVLQ
Sbjct: 348 LTDNQTSTMIRATARSAPDRQEEISKLMRSASFNTDPYVREFGIMVKDEMTDVTGRVLQP 407
Query: 449 PRLKFGNED---FNPRNGRWNFNNKKFVEPVSLGNWSVVNFSAR-----CDVRGLVRDLI 500
P + +G + P G W+ NK+F + + W++ F+ + ++ L
Sbjct: 408 PSILYGGRNKAIATPVQGVWDMRNKQFHTGIEIKVWAIACFAPQRQCTEVHLKSFTEQLR 467
Query: 501 KCGGMKGILVEQPKDVIEENRQFKGEPPVFRVEKMFADVLKLSKRPSFLLCLLPERKNSD 560
K G+ ++ + + P+FR K L+L ++ +LP + +
Sbjct: 468 KISRDAGMPIQGQPCFCKYAQGADSVEPMFRHLKNTYAGLQL------VVVILPGK--TP 519
Query: 561 LYGPWKKKNLAEFGIVTQCIAPT---RVNDQYLTNVLLKINAKLGGMNSWLGVEHSRSIP 617
+Y K+ G+ TQC+ R Q L+N+ LKIN KLGG+N+ L + P
Sbjct: 520 VYAEVKRVGDTVLGMATQCVQMKNVQRTTPQTLSNLCLKINVKLGGVNNIL---LPQGRP 576
Query: 618 IVSKVPTLILGMDVSHGSPGQPDIPSIAAVVSSRKWPLISKYRACVRTQGSKVEMIDNLF 677
V + P + LG DV+H G PSIAAVV S ++Y A VR Q + E+I +L
Sbjct: 577 PVFQQPVIFLGADVTHPPAGDGKKPSIAAVVGSMD-AHPNRYCATVRVQQHRQEIIQDL- 634
Query: 678 KPVSDKEDEGIIRELLLDFFHSSEERRPENIIIFRDGVSESQFNEVLNVELSQIIEACKF 737
++RELL+ F+ S+ + P II +RDGVSE QF +VL+ EL I EAC
Sbjct: 635 --------AAMVRELLIQFYKSTRFK-PTRIIFYRDGVSEGQFQQVLHHELLAIREACIK 685
Query: 738 LDENWNPKFMVIVAQKNHHTKFF------QPRSPDNVPPGTVVDSKICHPRNYDFYMCAH 791
L++++ P IV QK HHT+ F + N+P GT VD+KI HP +DFY+C+H
Sbjct: 686 LEKDYQPGITFIVVQKRHHTRLFCTDKNERVGKSGNIPAGTTVDTKITHPTEFDFYLCSH 745
Query: 792 AGMIGTSRPTHYHVLLDEIGFSPDDLQELVHSLSYVYQRSTTAISV 837
AG+ GTSRP+HYHVL D+ FS D+LQ L + L + Y R T ++S+
Sbjct: 746 AGIQGTSRPSHYHVLWDDNRFSSDELQILTYQLCHTYVRCTRSVSI 791
>I2C1_MOUSE (Q8CJG1) Eukaryotic translation initiation factor 2C 1
(eIF2C 1) (eIF-2C 1) (Piwi/argonaute family protain
meIF2C1)
Length = 857
Score = 332 bits (852), Expect = 2e-90
Identities = 238/828 (28%), Positives = 411/828 (48%), Gaps = 89/828 (10%)
Query: 43 RRGLGTKGAKLPLLTNHFEVNVANTNRVFFQYSVALFYEDGRPVEGKGAGRKIIDKVQET 102
R G+GT G + LL N+FEV++ + ++ + D P + R++++ + +
Sbjct: 26 RPGIGTVGKPIKLLANYFEVDIPKIDVYHYEVDIK---PDKCP---RRVNREVVEYMVQH 79
Query: 103 YDSELNG-KDLAYDG-ETLFTIGSL--AQKKLEFIVVVEDVASNRNNANTSPDKKRIRKS 158
+ ++ G + YDG E ++T+ +L ++++F V + +R
Sbjct: 80 FKPQIFGDRKPVYDGKENIYTVTALPIGNERVDFEVTIPGEGKDR--------------- 124
Query: 159 YRSKTYKVEINFAKEIPLQAIANALKGHEAENYQEAIRVLDIILRQHSAKQGCLLVRQNF 218
+KV I + + + + AL + E+++ LD+ +R H A V ++F
Sbjct: 125 ----IFKVSIKWLAIVSWRMLHEALVSGQIPVPLESVQALDVAMR-HLASMRYTPVGRSF 179
Query: 219 FHNDPNNLNDVGGGVLSCKGLHSSFRTTQSGLSLNIDVSTTMIVRPGPVVDFLIENQNVR 278
F + +GGG G H S R + LNIDVS T + PV++F+ E ++R
Sbjct: 180 FSPPEGYYHPLGGGREVWFGFHQSVRPAMWKMMLNIDVSATAFYKAQPVIEFMCEVLDIR 239
Query: 279 D----PFSLDWNKAKR---TLKNLRITAKPSNQ---EYKITGLSELSCKDQLFTMKKRGA 328
+ P L ++ R +K L++ Q +Y++ ++ Q F ++
Sbjct: 240 NIDEQPKPLTDSQRVRFTKEIKGLKVEVTHCGQMKRKYRVCNVTRRPASHQTFPLQLESG 299
Query: 329 VAGEDDTEEITVYDYFVHRRKIDLQYSAGLPCINVGKPKRPTYIPIELCSLISLQRYTKA 388
T E TV +F + + L+Y LPC+ VG+ ++ TY+P+E+C++++ QR K
Sbjct: 300 -----QTVECTVAQHFKQKYNLQLKYPH-LPCLQVGQEQKHTYLPLEVCNIVAGQRCIKK 353
Query: 389 LSTSQRSSLVEKSRQKPVERMRVLSNALKASNYGSEPMLRNCGISITSEFTQVDGRVLQA 448
L+ +Q S++++ + + +R +S +K ++ +P ++ GI + + T+V GRVL A
Sbjct: 354 LTDNQTSTMIKATARSAPDRQEEISRLMKNASCNLDPYIQEFGIKVKDDMTEVTGRVLPA 413
Query: 449 PRLKFGNED---FNPRNGRWNFNNKKFVEPVSLGNWSVVNFSARCDVRGLVRDLIKCGGM 505
P L++G + P G W+ K+F + + W++ F+ + R V +
Sbjct: 414 PILQYGGRNRAIATPNQGVWDMRGKQFYNGIEIKVWAIACFAPQKQCREEV--------L 465
Query: 506 KGILVEQPKDVIEENRQFKGEPPVFR-------VEKMFADVLKLSKRPSFLLCLLPERKN 558
K + K + +G+P + VE MF + ++ +LP +
Sbjct: 466 KNFTDQLRKISKDAGMPIQGQPCFCKYAQGADSVEPMFRHLKNTYSGLQLIIVILPGK-- 523
Query: 559 SDLYGPWKKKNLAEFGIVTQCIA---PTRVNDQYLTNVLLKINAKLGGMNSWLGVEHSRS 615
+ +Y K+ G+ TQC+ + + Q L+N+ LKIN KLGG+N+ L V H RS
Sbjct: 524 TPVYAEVKRVGDTLLGMATQCVQVKNAVKTSPQTLSNLCLKINVKLGGINNIL-VPHQRS 582
Query: 616 IPIVSKVPTLILGMDVSHGSPGQPDIPSIAAVVSSRKWPLISKYRACVRTQGSKVEMIDN 675
V + P + LG DV+H G PSI AVV S S+Y A VR Q + E+I++
Sbjct: 583 A--VFQQPVIFLGADVTHPPAGDGKKPSITAVVGSMD-AHPSRYCATVRVQRPRQEIIED 639
Query: 676 LFKPVSDKEDEGIIRELLLDFFHSSEERRPENIIIFRDGVSESQFNEVLNVELSQIIEAC 735
L ++RELL+ F+ S+ + P II +RDGV E Q ++L+ EL I +AC
Sbjct: 640 L---------SYMVRELLIQFYKSTRFK-PTRIIFYRDGVPEGQLPQILHYELLAIRDAC 689
Query: 736 KFLDENWNPKFMVIVAQKNHHTKFFQPRSPD------NVPPGTVVDSKICHPRNYDFYMC 789
L++++ P IV QK HHT+ F + N+P GT VD+ I HP +DFY+C
Sbjct: 690 IKLEKDYQPGITYIVVQKRHHTRLFCADKNERIGKSGNIPAGTTVDTNITHPFEFDFYLC 749
Query: 790 AHAGMIGTSRPTHYHVLLDEIGFSPDDLQELVHSLSYVYQRSTTAISV 837
+HAG+ GTSRP+HY+VL D+ F+ D+LQ L + L + Y R T ++S+
Sbjct: 750 SHAGIQGTSRPSHYYVLWDDNRFTADELQILTYQLCHTYVRCTRSVSI 797
>I2C3_MOUSE (Q8CJF9) Eukaryotic translation initiation factor 2C 3
(eIF2C 3) (eIF-2C 3) (Piwi/argonaute family protain
meIF2C3)
Length = 860
Score = 330 bits (846), Expect = 1e-89
Identities = 250/835 (29%), Positives = 405/835 (47%), Gaps = 94/835 (11%)
Query: 43 RRGLGTKGAKLPLLTNHFEVNVANTNRVFFQYSVALFYEDGRPVE-GKGAGRKIID-KVQ 100
R G GT G + LL N F+V + + V L+ D +P + + R+++D KVQ
Sbjct: 20 RPGYGTMGKPIKLLANCFQVEIP-------KIDVYLYEVDIKPDKCPRRVNREVVDSKVQ 72
Query: 101 ETYDSELNGKDLAYDGE-TLFTIGSLAQKKLEFIVVVEDVASNRNNANTSPDKKRIRKSY 159
+ + YDG+ +L+T L VA+ D +
Sbjct: 73 HFKVTIFGDRRPVYDGKRSLYTANPL------------PVAT----TGVDLDVTLPGEGG 116
Query: 160 RSKTYKVEINFAKEIPLQAIANALKGHEAENYQE--------AIRVLDIILRQHSAKQGC 211
+ + +KV + F + + AL G E + +D++LR H
Sbjct: 117 KDRPFKVSVKFVSRVSWHLLHEALAGGTLPEPLELDKPVSTNPVHAVDVVLR-HLPSMKY 175
Query: 212 LLVRQNFFHNDPNNLNDVGGGVLSCKGLHSSFRTTQSGLSLNIDVSTTMIVRPGPVVDFL 271
V ++FF + +GGG G H S R + LNIDVS T + PV+ F+
Sbjct: 176 TPVGRSFFSAPEGYDHPLGGGREVWFGFHQSVRPAMWKMMLNIDVSATAFYKAQPVIQFM 235
Query: 272 IENQNVRD----PFSL-DWNKAKRT--LKNLRITAK---PSNQEYKITGLSELSCKDQLF 321
E ++ + P L D ++ K T +K L++ ++Y++ ++ Q F
Sbjct: 236 CEVLDIHNIDEQPRPLTDSHRVKFTKEIKGLKVEVTHCGTMRRKYRVCNVTRRPASHQTF 295
Query: 322 TMKKRGAVAGEDDTEEITVYDYFVHRRKIDLQYSAGLPCINVGKPKRPTYIPIELCSLIS 381
++ T E TV YF + + L+Y LPC+ VG+ ++ TY+P+E+C++++
Sbjct: 296 PLQLENG-----QTVERTVAQYFREKYTLQLKY-PHLPCLQVGQEQKHTYLPLEVCNIVA 349
Query: 382 LQRYTKALSTSQRSSLVEKSRQKPVERMRVLSNALKASNYGSEPMLRNCGISITSEFTQV 441
QR K L+ +Q S++++ + + +R +S ++++NY ++P ++ + + E V
Sbjct: 350 GQRCIKKLTDNQTSTMIKATARSAPDRQEEISRLVRSANYETDPFVQEFQLKVRDEMAHV 409
Query: 442 DGRVLQAPRLKFGNED---FNPRNGRWNFNNKKFVEPVSLGNWSVVNFSARCDVRGLVRD 498
GRVL AP L++G + P +G W+ K+F V + W++ F+ + R +
Sbjct: 410 TGRVLPAPMLQYGGRNRTVATPSHGVWDMRGKQFHTGVEIKMWAIACFATQRQCREEI-- 467
Query: 499 LIKCGGMKGILVEQPKDVIEENRQFKGEPPVFR-------VEKMFADVLKLSKRPSFLLC 551
+KG + K + +G+P + VE MF + ++
Sbjct: 468 ------LKGFTDQLRKISKDAGMPIQGQPCFCKYAQGADSVEPMFRHLKNTYSGLQLIIV 521
Query: 552 LLPERKNSDLYGPWKKKNLAEFGIVTQCIAPTRV---NDQYLTNVLLKINAKLGGMNSWL 608
+LP + + +Y K+ G+ TQC+ V + Q L+N+ LKIN KLGG+N+ L
Sbjct: 522 ILPGK--TPVYAEVKRVGDTLLGMATQCVQVKNVIKTSPQTLSNLCLKINVKLGGINNIL 579
Query: 609 GVEHSRSIPIVSKVPTLILGMDVSHGSPGQPDIPSIAAVVSSRKWPLISKYRACVRTQGS 668
V H R P V + P + LG DV+H G PSIAAVV S S+Y A VR Q
Sbjct: 580 -VPHQR--PSVFQQPVIFLGADVTHPPAGDGKKPSIAAVVGSMD-AHPSRYCATVRVQRP 635
Query: 669 KVEMIDNLFKPVSDKEDEGIIRELLLDFFHSSEERRPENIIIFRDGVSESQFNEVLNVEL 728
+ E+I +L ++RELL+ F+ S+ +P II +RDGVSE QF +VL EL
Sbjct: 636 RQEIIQDL---------ASMVRELLIQFYKST-RFKPTRIIFYRDGVSEGQFRQVLYYEL 685
Query: 729 SQIIEACKFLDENWNPKFMVIVAQKNHHTKFF------QPRSPDNVPPGTVVDSKICHPR 782
I EAC L++++ P IV QK HHT+ F + N+P GT VD+ I HP
Sbjct: 686 LAIREACISLEKDYQPGITYIVVQKRHHTRLFCADRTERVGRSGNIPAGTTVDTDITHPY 745
Query: 783 NYDFYMCAHAGMIGTSRPTHYHVLLDEIGFSPDDLQELVHSLSYVYQRSTTAISV 837
+DFY+C+HAG+ GTSRP+HYHVL D+ F+ D+LQ L + L + Y R T ++S+
Sbjct: 746 EFDFYLCSHAGIQGTSRPSHYHVLWDDNFFTADELQLLTYQLCHTYVRCTRSVSI 800
>I2C3_HUMAN (Q9H9G7) Eukaryotic translation initiation factor 2C 3
(eIF2C 3) (eIF-2C 3) (Argonaute 3)
Length = 860
Score = 327 bits (837), Expect = 1e-88
Identities = 247/835 (29%), Positives = 403/835 (47%), Gaps = 94/835 (11%)
Query: 43 RRGLGTKGAKLPLLTNHFEVNVANTNRVFFQYSVALFYEDGRPVE-GKGAGRKIIDKVQE 101
R G G G + LL N F+V + + V L+ D +P + + R+++D + +
Sbjct: 20 RPGYGAMGKPIKLLANCFQVEIP-------KIDVYLYEVDIKPDKCPRRVNREVVDSMVQ 72
Query: 102 TYDSELNG-KDLAYDGE-TLFTIGSLAQKKLEFIVVVEDVASNRNNANTSPDKKRIRKSY 159
+ + G + YDG+ +L+T L VA+ D +
Sbjct: 73 HFKVTIFGDRRPVYDGKRSLYTANPL------------PVAT----TGVDLDVTLPGEGG 116
Query: 160 RSKTYKVEINFAKEIPLQAIANALKGHEAENYQE--------AIRVLDIILRQHSAKQGC 211
+ + +KV I F + + L G E + +D++LR H
Sbjct: 117 KDRPFKVSIKFVSRVSWHLLHEVLTGRTLPEPLELDKPISTNPVHAVDVVLR-HLPSMKY 175
Query: 212 LLVRQNFFHNDPNNLNDVGGGVLSCKGLHSSFRTTQSGLSLNIDVSTTMIVRPGPVVDFL 271
V ++FF + +GGG G H S R + LNIDVS T + PV+ F+
Sbjct: 176 TPVGRSFFSAPEGYDHPLGGGREVWFGFHQSVRPAMWKMMLNIDVSATAFYKAQPVIQFM 235
Query: 272 IENQNVRD----PFSL-DWNKAKRT--LKNLRITAK---PSNQEYKITGLSELSCKDQLF 321
E ++ + P L D ++ K T +K L++ ++Y++ ++ Q F
Sbjct: 236 CEVLDIHNIDEQPRPLTDSHRVKFTKEIKGLKVEVTHCGTMRRKYRVCNVTRRPASHQTF 295
Query: 322 TMKKRGAVAGEDDTEEITVYDYFVHRRKIDLQYSAGLPCINVGKPKRPTYIPIELCSLIS 381
++ T E TV YF + + L+Y LPC+ VG+ ++ TY+P+E+C++++
Sbjct: 296 PLQLENG-----QTVERTVAQYFREKYTLQLKY-PHLPCLQVGQEQKHTYLPLEVCNIVA 349
Query: 382 LQRYTKALSTSQRSSLVEKSRQKPVERMRVLSNALKASNYGSEPMLRNCGISITSEFTQV 441
QR K L+ +Q S++++ + + +R +S ++++NY ++P ++ + E V
Sbjct: 350 GQRCIKKLTDNQTSTMIKATARSAPDRQEEISRLVRSANYETDPFVQEFQFKVRDEMAHV 409
Query: 442 DGRVLQAPRLKFGNED---FNPRNGRWNFNNKKFVEPVSLGNWSVVNFSARCDVRGLVRD 498
GRVL AP L++G + P +G W+ K+F V + W++ F+ + R +
Sbjct: 410 TGRVLPAPMLQYGGRNRTVATPSHGVWDMRGKQFHTGVEIKMWAIACFATQRQCREEI-- 467
Query: 499 LIKCGGMKGILVEQPKDVIEENRQFKGEPPVFR-------VEKMFADVLKLSKRPSFLLC 551
+KG + K + +G+P + VE MF + ++
Sbjct: 468 ------LKGFTDQLRKISKDAGMPIQGQPCFCKYAQGADSVEPMFRHLKNTYSGLQLIIV 521
Query: 552 LLPERKNSDLYGPWKKKNLAEFGIVTQCIAPTRV---NDQYLTNVLLKINAKLGGMNSWL 608
+LP + + +Y K+ G+ TQC+ V + Q L+N+ LKIN KLGG+N+ L
Sbjct: 522 ILPGK--TPVYAEVKRVGDTLLGMATQCVQVKNVIKTSPQTLSNLCLKINVKLGGINNIL 579
Query: 609 GVEHSRSIPIVSKVPTLILGMDVSHGSPGQPDIPSIAAVVSSRKWPLISKYRACVRTQGS 668
V H R P V + P + LG DV+H G PSIAAVV S S+Y A VR Q
Sbjct: 580 -VPHQR--PSVFQQPVIFLGADVTHPPAGDGKKPSIAAVVGSMD-AHPSRYCATVRVQRP 635
Query: 669 KVEMIDNLFKPVSDKEDEGIIRELLLDFFHSSEERRPENIIIFRDGVSESQFNEVLNVEL 728
+ E+I +L ++RELL+ F+ S+ +P II +RDGVSE QF +VL EL
Sbjct: 636 RQEIIQDL---------ASMVRELLIQFYKST-RFKPTRIIFYRDGVSEGQFRQVLYYEL 685
Query: 729 SQIIEACKFLDENWNPKFMVIVAQKNHHTKFF------QPRSPDNVPPGTVVDSKICHPR 782
I EAC L++++ P IV QK HHT+ F + N+P GT VD+ I HP
Sbjct: 686 LAIREACISLEKDYQPGITYIVVQKRHHTRLFCADRTERVGRSGNIPAGTTVDTDITHPY 745
Query: 783 NYDFYMCAHAGMIGTSRPTHYHVLLDEIGFSPDDLQELVHSLSYVYQRSTTAISV 837
+DFY+C+HAG+ GTSRP+HYHVL D+ F+ D+LQ L + L + Y R T ++S+
Sbjct: 746 EFDFYLCSHAGIQGTSRPSHYHVLWDDNCFTADELQLLTYQLCHTYVRCTRSVSI 800
>AGO1_SCHPO (O74957) Cell cycle control protein ago1 (RNA
interference pathway protein ago1)
Length = 834
Score = 306 bits (784), Expect = 2e-82
Identities = 241/837 (28%), Positives = 402/837 (47%), Gaps = 94/837 (11%)
Query: 36 PTKAPMARRGLGTKGAKLPLLTNHFEVNVANTNRVFFQYSVALFYEDGRPVEGKGAGRKI 95
P+ R G G G ++ L N F++ ++ N QY V + DG V K +
Sbjct: 5 PSSEIALRPGYGGLGKQITLKANFFQI-ISLPNETINQYHVIV--GDGSRVPRKQSQLIW 61
Query: 96 IDKVQETYDSELNGKDLAYDGETL-FTIGSLAQKKLEFIVVVEDVASNRNNANTSPDKKR 154
K + Y + + YDG ++ ++ G +A + K
Sbjct: 62 NSKEVKQYFGS-SWMNSVYDGRSMCWSKGDIADGTI---------------------KVN 99
Query: 155 IRKSYRSKTYKVEINFAKEIPLQAIANALKGHEAENYQ--EAIRVLDIILRQHSAKQGCL 212
I + + I + +I L ++ + + + Q +I LD++L++ ++ L
Sbjct: 100 IGSESHPREIEFSIQKSSKINLHTLSQFVNSKYSSDPQVLSSIMFLDLLLKKKPSET--L 157
Query: 213 LVRQNFFHNDPNNLNDVGGGVLSCKGLHSSFRTTQSGLSLNIDVSTTMIVRPGPVVDFLI 272
+ F N ++ +GGGV + KG + S R Q +S+N+D+S++ R ++ L+
Sbjct: 158 FGFMHSFFTGENGVS-LGGGVEAWKGFYQSIRPNQGFMSVNVDISSSAFWRNDSLLQILM 216
Query: 273 EN---QNVRDPFSLDWNKAKRTLKNLRITAKP--------SNQEYKITGLSELSCKDQLF 321
E NVRD D + R + L++T + +N+ Y I G S S D F
Sbjct: 217 EYTDCSNVRDLTRFDLKRLSRKFRFLKVTCQHRNNVGTDLANRVYSIEGFSSKSASDSFF 276
Query: 322 TMKKRGAVAGEDDTEEITVYDYFVHRRKIDLQYSAGLPCINVGKPKRPTYIPIELCSLIS 381
+ G + ++I+V +YF+ + LQY LPCI V K +PIE C ++
Sbjct: 277 VRRLNG------EEQKISVAEYFLENHNVRLQYP-NLPCILV---KNGAMLPIEFCFVVK 326
Query: 382 LQRYTKALSTSQRSSLVEKSRQKPVERMRVLSNALKASNYGSEPMLRNCGISITSEFTQV 441
QRYT L++ Q ++++ + Q+P ER++ + + + ++ ++P L G+ I + +V
Sbjct: 327 GQRYTAKLNSDQTANMIRFAVQRPFERVQQIDDFVHQMDWDTDPYLTQYGMKIQKKMLEV 386
Query: 442 DGRVLQAPRLKFGNEDFN-PRNGRWNFNNKKFVEP--VSLGNWSVVNFSA--RCDVRGL- 495
RVL+ P +++G + P +GRWN K+F++P + +W+V+ F++ R +RG+
Sbjct: 387 PARVLETPSIRYGGDCIERPVSGRWNLRGKRFLDPPRAPIRSWAVMCFTSTRRLPMRGIE 446
Query: 496 ------VRDLIKCGGMKGILVEQPKDVIEENRQFKGEPPVFRVEKMFADVLKLSKRPSFL 549
V+ L G ++++P + + R E + ++ ++ P
Sbjct: 447 NFLQTYVQTLTSLG--INFVMKKPPVLYADIRGSVEELCI----TLYKKAEQVGNAPPDY 500
Query: 550 LCLLPERKNSDLYGPWKKKNLAEFGIVTQCIAPTRV---NDQYLTNVLLKINAKLGGMNS 606
L + ++ + + YG K+ G+ +QC + QY N+ +KIN K+GG+N
Sbjct: 501 LFFILDKNSPEPYGSIKRVCNTMLGVPSQCAISKHILQSKPQYCANLGMKINVKVGGINC 560
Query: 607 WLGVEHSRSIPIVSKVPTLILGMDVSHGSPGQPDIPSIAAVVSSRKWPLISKYRACVRTQ 666
L +S P+ VPTLILG DV H G + SIA++V+S KY A R+Q
Sbjct: 561 SL---IPKSNPL-GNVPTLILGGDVYHPGVGATGV-SIASIVASVDLNGC-KYTAVSRSQ 614
Query: 667 GSKVEMIDNLFKPVSDKEDEGIIRELLLDFFHSSEERRPENIIIFRDGVSESQFNEVLNV 726
E+I+ + V LL F + +++P+ II FRDG SE QF V+N
Sbjct: 615 PRHQEVIEGMKDIVV----------YLLQGFRAMTKQQPQRIIYFRDGTSEGQFLSVIND 664
Query: 727 ELSQIIEACKFLDENWNPKFMVIVAQKNHHTKFFQPRSPD-----NVPPGTVVDSKICHP 781
ELSQI EAC L +NPK +V QK HH +FF D N PGT+++ + HP
Sbjct: 665 ELSQIKEACHSLSPKYNPKILVCTTQKRHHARFFIKNKSDGDRNGNPLPGTIIEKHVTHP 724
Query: 782 RNYDFYMCAHAGMIGTSRPTHYHVLLDEIGFSPDDLQELVHSLSYVYQRSTTAISVV 838
YDFY+ +H + G S P HY VL DEI PD Q L ++L YVY R+T+A+S+V
Sbjct: 725 YQYDFYLISHPSLQGVSVPVHYTVLHDEIQMPPDQFQTLCYNLCYVYARATSAVSLV 781
>YO43_CAEEL (P34681) Hypothetical protein ZK757.3 in chromosome III
Length = 1040
Score = 252 bits (643), Expect = 3e-66
Identities = 159/519 (30%), Positives = 277/519 (52%), Gaps = 37/519 (7%)
Query: 339 TVYDYFVHRRKIDLQYSAGLPCINVGKPKRPTYIPIELCSLISLQRYTKALSTSQRSSLV 398
+V DYF + L+Y LPC++VG P R ++P+E C + S Q+Y K +S Q S+++
Sbjct: 446 SVADYFSEKYG-PLKYPK-LPCLHVGPPTRNIFLPMEHCLIDSPQKYNKKMSEKQTSAII 503
Query: 399 EKSRQKPVERMRVLSNALKASNYGSEPMLRNCGISITSEFTQVDGRVLQAPRLKFG--NE 456
+ + +R + +++G++P L+ G++++S+ Q RV+Q P + FG N
Sbjct: 504 KAAAVDATQREDRIKQLAAQASFGTDPFLKEFGVAVSSQMIQTTARVIQPPPIMFGGNNR 563
Query: 457 DFNP----RNGRWNFNNKKFVEPVSLGNWSVVNFSARCDVRGL---VRDLIKCGGMKGIL 509
NP ++G W +N+ P + ++S++ D L + L G+
Sbjct: 564 SVNPVVFPKDGSWTMDNQTLYMPATCRSYSMIALVDPRDQTSLQTFCQSLTMKATAMGMN 623
Query: 510 VEQPKDVIEENRQFKGEPPVFRVEKMFADVLKLSKRPSFLLCLLPERKNSDLYGPWKKKN 569
+ D+++ R + +F AD +++ + ++ + KNSD+Y K+++
Sbjct: 624 FPRWPDLVKYGRSKEDVCTLFTE---IADEYRVTNTVCDCIIVVLQSKNSDIYMTVKEQS 680
Query: 570 LAEFGIVTQCIAPTRVN---DQYLTNVLLKINAKLGGMNSWLGVEHSRSIPIVSKVPTLI 626
GI++QC+ V+ N++LK+N K+GG+NS + + + +V + PT++
Sbjct: 681 DIVHGIMSQCVLMKNVSRPTPATCANIVLKLNMKMGGINSRIVADKITNKYLVDQ-PTMV 739
Query: 627 LGMDVSHGSPGQP--DIPSIAAVVSSRKWPLISKYRACVRTQGSKVEMIDNLFKPVSDKE 684
+G+DV+H + + ++PS+AA+V++ L Y A V+ Q E + L
Sbjct: 740 VGIDVTHPTQAEMRMNMPSVAAIVANVDL-LPQSYGANVKVQKKCRESVVYLLDA----- 793
Query: 685 DEGIIRELLLDFFHSSEERRPENIIIFRDGVSESQFNEVLNVELSQIIEACKFLDENWNP 744
IRE ++ F+ ++++ P II++RDGVSE QF+EVL E+ I AC + E++ P
Sbjct: 794 ----IRERIITFYRHTKQK-PARIIVYRDGVSEGQFSEVLREEIQSIRTACLAIAEDFRP 848
Query: 745 KFMVIVAQKNHHTKFFQPRSPD------NVPPGTVVDSKICHPRNYDFYMCAHAGMIGTS 798
IV QK HH + F D NVPPGT VD+ I P +DFY+C+H G+ GTS
Sbjct: 849 PITYIVVQKRHHARIFCKYQNDMVGKAKNVPPGTTVDTGIVSPEGFDFYLCSHYGVQGTS 908
Query: 799 RPTHYHVLLDEIGFSPDDLQELVHSLSYVYQRSTTAISV 837
RP YHVLLDE F+ D++Q + + + + Y R T ++S+
Sbjct: 909 RPARYHVLLDECKFTADEIQSITYGMCHTYGRCTRSVSI 947
Score = 43.1 bits (100), Expect = 0.003
Identities = 70/254 (27%), Positives = 109/254 (42%), Gaps = 34/254 (13%)
Query: 41 MARRGLGTKGAKLPLLTNHFEVNVANTNRVFFQYSVALFYEDGRPVEGKGAGRKIIDKVQ 100
+AR GLGT G ++P+ +N F +++ N V QY V + + R ++ K R I K
Sbjct: 87 VARPGLGTIGRQIPVKSNFFAMDLKNPKMVVIQYHVEIHHPGCRKLD-KDEMRIIFWKAV 145
Query: 101 ETYDSELNGK-DLAYDG-ETLFTIGSLAQKKLEFIVVVEDVASNRNNANTSPDKKRIRKS 158
+ + + K LAYDG L+T+ +LEF +D S R + S + K
Sbjct: 146 SDHPNIFHNKFALAYDGAHQLYTVA-----RLEF---PDDQGSVRLDCEAS-----LPKD 192
Query: 159 YRSKTYKVEINFAKEIP-LQAIANALKGHEAENYQEAIRVLDIILRQHSAKQGCLLVRQ- 216
R +T + I+ P L + + E I++LDII RQ C L++
Sbjct: 193 NRDRT-RCAISIQNVGPVLLEMQRTRTNNLDERVLTPIQILDIICRQSLT---CPLLKNS 248
Query: 217 -NFF------HNDPNNLN---DVGGGVLSCKGLHSSFRTTQSGLS-LNIDVSTTMIVRPG 265
NF+ + P D+ GG G SS + LNIDV+ T +
Sbjct: 249 ANFYTWKSSCYRIPTAAGQALDLEGGKEMWTGFFSSAHIASNYRPLLNIDVAHTAFYKTR 308
Query: 266 -PVVDFLIENQNVR 278
V+ F+ + N R
Sbjct: 309 ITVLQFMCDVLNER 322
>AGO2_DROME (Q9VUQ5) Argonaute 2 protein
Length = 1214
Score = 244 bits (623), Expect = 7e-64
Identities = 211/821 (25%), Positives = 383/821 (45%), Gaps = 95/821 (11%)
Query: 47 GTKGAKLPLLTNHFEVNVANTNRVFFQYSVALFYEDGRPVEGKGAGRKIIDKVQETYD-S 105
GT G + N+ +++++ V + Y V + E RP +K + E +
Sbjct: 408 GTIGKPGQVGINYLDLDLSKMPSVAYHYDVKIMPE--RP-------KKFYRQAFEQFRVD 458
Query: 106 ELNGKDLAYDGE-TLFTIGSLAQKKLEFIVVVEDVASNRNNANTSPDKKRIRKSYRSKTY 164
+L G LAYDG+ + +++ L V V D ++ R+ Y
Sbjct: 459 QLGGAVLAYDGKASCYSVDKLPLNSQNPEVTVTD------------------RNGRTLRY 500
Query: 165 KVEINFAKE--IPLQAIANALKGHEAENYQEAIRVLDIILRQHSAKQGCLLVRQNFFHND 222
+EI + I L+++ + + A++ ++++L + + R F +D
Sbjct: 501 TIEIKETGDSTIDLKSLTTYMNDRIFDKPMRAMQCVEVVLASPCHNKAIRVGRSFFKMSD 560
Query: 223 PNNLNDVGGGVLSCKGLHSSFRTTQSGLSLNIDVSTTMIVRPGPVVDFLIE---NQNVRD 279
PNN +++ G + GL+ +F LN+D+S P++++L + +
Sbjct: 561 PNNRHELDDGYEALVGLYQAFMLGDRPF-LNVDISHKSFPISMPMIEYLERFSLKAKINN 619
Query: 280 PFSLDWNKA--KRTLKNLRITAKPSN------QEYKITGLSELSCKDQLFTMKKRGAVAG 331
+LD+++ + L+ + + P + Y++ GLS + F
Sbjct: 620 TTNLDYSRRFLEPFLRGINVVYTPPQSFQSAPRVYRVNGLSRAPASSETF---------- 669
Query: 332 EDDTEEITVYDYFVHRRKIDLQYSAGLPCINVGKPKRPTYIPIELCSLISLQRYTKALST 391
E D +++T+ YF H R L++ L C+NVG + +PIELCS+ Q +
Sbjct: 670 EHDGKKVTIASYF-HSRNYPLKFPQ-LHCLNVGSSIKSILLPIELCSIEEGQALNRKDGA 727
Query: 392 SQRSSLVEKSRQKPVERMRVLSNALKASNYGSEPMLRNCGISITSEFTQVDGRVLQAPRL 451
+Q +++++ + R R + N L+ + +P + GI I ++F V RVL P++
Sbjct: 728 TQVANMIKYAATSTNVRKRKIMNLLQYFQHNLDPTISRFGIRIANDFIVVSTRVLSPPQV 787
Query: 452 KFGNEDFNP-RNGRWNFNNKKFVEPVSLGNWSVVNFSARCDVR-GLVRDLIKCGGMKGIL 509
++ ++ F +NG W + KF+EP + V + CD R G + + ++
Sbjct: 788 EYHSKRFTMVKNGSWRMDGMKFLEPKPKAHKCAVLY---CDPRSGRKMNYTQLNDFGNLI 844
Query: 510 VEQPKDV---IEENRQFKGEPPVFR-VEKMFADVLKLSKRPSFLLCLLPERKNSDLYGPW 565
+ Q K V ++ + ++ R ++ +FAD LK S+ + ++P+ + S Y
Sbjct: 845 ISQGKAVNISLDSDVTYRPFTDDERSLDTIFAD-LKRSQH-DLAIVIIPQFRIS--YDTI 900
Query: 566 KKKNLAEFGIVTQCIAPTRV----NDQYLTNVLLKINAKLGGMNSWLGVEHSRSIPIVSK 621
K+K + GI+TQCI V N+Q + N+LLKIN+KL G+N ++ +P++
Sbjct: 901 KQKAELQHGILTQCIKQFTVERKCNNQTIGNILLKINSKLNGINH--KIKDDPRLPMMKN 958
Query: 622 VPTLILGMDVSHGSPGQPDIPSIAAVVSSRKWPLISKYRACVRTQGSKVEMIDNLFKPVS 681
T+ +G DV+H SP Q +IPS+ V +S P + Y R Q +E I+++F
Sbjct: 959 --TMYIGADVTHPSPDQREIPSVVGVAASHD-PYGASYNMQYRLQRGALEEIEDMFSITL 1015
Query: 682 DKEDEGIIRELLLDFFHSSEERRPENIIIFRDGVSESQFNEVLNVELSQIIEACKFLDEN 741
+ L + P++II +RDGVS+ QF ++ N EL I +AC +
Sbjct: 1016 EH----------LRVYKEYRNAYPDHIIYYRDGVSDGQFPKIKNEELRCIKQACDKV--G 1063
Query: 742 WNPKFMVIVAQKNHHTKFFQPRSP------DNVPPGTVVDSKICHPRNYDFYMCAHAGMI 795
PK ++ K HHT+FF +NV PGTVVD I HP F+M +H +
Sbjct: 1064 CKPKICCVIVVKRHHTRFFPSGDVTTSNKFNNVDPGTVVDRTIVHPNEMQFFMVSHQAIQ 1123
Query: 796 GTSRPTHYHVLLDEIGFSPDDLQELVHSLSYVYQRSTTAIS 836
GT++PT Y+V+ + D LQ+L ++L +++ R ++S
Sbjct: 1124 GTAKPTRYNVIENTGNLDIDLLQQLTYNLCHMFPRCNRSVS 1164
>PIWI_BRARE (Q8UVX0) Piwi protein
Length = 858
Score = 143 bits (361), Expect = 2e-33
Identities = 153/616 (24%), Positives = 271/616 (43%), Gaps = 73/616 (11%)
Query: 238 GLHSSFRTTQSGLSLNIDVSTTMIVRPGPVVDFLIE-NQNVRDPFSLDWNKAKRTLKNLR 296
G ++ +S + L DVS ++R V+DF+ Q D + + L L
Sbjct: 249 GFMTTILQYESSIMLCSDVSHK-VLRSETVLDFMYSLRQQCGDQRFPE--ACTKELVGLI 305
Query: 297 ITAKPSNQEYKITGLSELSCKDQLFTMKKRGAVAGEDDTEEITVYDYFVHRRKIDLQYSA 356
I K +N+ Y+I ++ + F K+G DTE I+ +YF + +D+
Sbjct: 306 ILTKYNNKTYRIDDIAWDHTPNNTF---KKG------DTE-ISFKNYFKSQYGLDITDGN 355
Query: 357 GLPCINVGK--------PKRPTYIPIELCSLISLQRYTKALSTSQRSSLVEKSRQKPVER 408
+ ++ K P P + E C L L +A + L +R P +R
Sbjct: 356 QVLLVSHVKRLGPSGRPPPGPAMLVPEFCYLTGLTDKMRA-DFNIMKDLASHTRLSPEQR 414
Query: 409 M----RVLSNALKASNYGSEPMLRNCGISITSEFTQVDGRVLQAPRLKFGNE--DFNPRN 462
R++SN + + +E L G+S ++ ++GRVL + R+ G ++NP
Sbjct: 415 EGRINRLISNINRNGDVQNE--LTTWGLSFENKLLSLNGRVLPSERIIQGGRAFEYNPWT 472
Query: 463 GRWN--FNNKKFVEPVSLGNWSVVNFSARCDV-RGLVRDLIKCGGMKGILVEQPKDVIEE 519
W+ + +SL NW + DV + L++ L K G GI +++ + E
Sbjct: 473 ADWSKEMRGLPLISCMSLDNWLMFYTRRNADVAQSLLQTLNKVSGPMGIRMQRAVMIEYE 532
Query: 520 NRQFKGEPPVFRVEKMFADVLKLSKRPSFLLCLLPERKNSDLYGPWKKKNLAEFGIVTQC 579
+RQ E + + + R + ++ ++ D Y KK + +QC
Sbjct: 533 DRQ----------ESLLRALQQNVARETQMVVVILPTNRKDKYDCVKKYLCVDCPTPSQC 582
Query: 580 IAPTRVNDQYL-----TNVLLKINAKLGGMNSWLGVEHSRSIPIVSKVPTLILGMDVSHG 634
+ ++ T + L++N K+GG W S IP+ +I+G+D H
Sbjct: 583 VVSRTISKPQALMTVATKIALQMNCKMGG-ELW-----SVEIPLRQ---LMIVGIDCYHD 633
Query: 635 SPGQPDIPSIAAVVSSRKWPLISKYRACVRTQGSKVEMIDNLFKPVSDKEDEGIIRELLL 694
+ SI A+V+S + + CV Q E+ID L +G ++ L
Sbjct: 634 TAAGKR--SIGAMVASLNQGMSRWFSKCV-LQNRGQEIIDAL---------KGSLQGALK 681
Query: 695 DFFHSSEERRPENIIIFRDGVSESQFNEVLNVELSQIIEACKFLDENWNPKFMVIVAQKN 754
+ + P II++RDGV + V++ E+ QI+++ K + +++ PK V+V +K
Sbjct: 682 AYLKYNNSL-PSRIIVYRDGVGDGMLQSVVDYEVPQIMQSIKTMGQDYEPKLSVVVVKKR 740
Query: 755 HHTKFFQPRSPD--NVPPGTVVDSKICHPRNYDFYMCAHAGMIGTSRPTHYHVLLDEIGF 812
++FF N PPGTV+D+++ P YDF++ + A G PTHY+V+ D G
Sbjct: 741 ISSRFFARIDGKIANPPPGTVIDTEVTRPEWYDFFIVSQAVRFGCVAPTHYNVVFDNSGL 800
Query: 813 SPDDLQELVHSLSYVY 828
PD +Q L + L ++Y
Sbjct: 801 KPDHMQRLTYKLCHMY 816
>PIWI_DROME (Q9VKM1) Piwi protein
Length = 843
Score = 125 bits (314), Expect = 5e-28
Identities = 152/687 (22%), Positives = 298/687 (43%), Gaps = 78/687 (11%)
Query: 195 IRVLDIILRQHSAKQGCLLVRQNFFHNDPNNLNDVGGGVLSC-KGLHSSFRTTQSGLSLN 253
++VL++ILR+ LV +N F DP ++ + G +S R + + L
Sbjct: 194 LQVLNLILRRSMKGLNLELVGRNLF--DPRAKIEIREFKMELWPGYETSIRQHEKDILLG 251
Query: 254 IDVSTTMIVRPGPVVDFLIENQNVRDPFSLDWNKAKRTLKNLRITAKPSNQEYKITGLSE 313
++ T ++R + D + + +P + ++ + + +L + +N+ Y+I +
Sbjct: 252 TEI-THKVMRTETIYDIM--RRCSHNP-ARHQDEVRVNVLDLIVLTDYNNRTYRINDVDF 307
Query: 314 LSCKDQLFTMKKRGAVAGEDDTEEITVYDYFVHRRKIDLQYSAGLPCINVGKPKR----- 368
F+ K R +I+ +Y++ + I ++ I+ + K
Sbjct: 308 GQTPKSTFSCKGR----------DISFVEYYLTKYNIRIRDHNQPLLISKNRDKALKTNA 357
Query: 369 ---PTYIPIELCSLISLQRYTKALSTSQR--SSLVEKSRQKPVERMRVLSNALKASNYGS 423
IP ELC + L ++ R SS + ++ +R+R ++ L+ + S
Sbjct: 358 SELVVLIP-ELCRVTGLNAEMRSNFQLMRAMSSYTRMNPKQRTDRLRAFNHRLQ-NTPES 415
Query: 424 EPMLRNCGISITSEFTQVDGRVLQAPRLKFGNEDFNP-RNGRW--NFNNKKFVEPVS--L 478
+LR+ + + T+V GR++ + F N N W +F +++ + S L
Sbjct: 416 VKVLRDWNMELDKNVTEVQGRIIGQQNIVFHNGKVPAGENADWQRHFRDQRMLTTPSDGL 475
Query: 479 GNWSVVNFSARC-DVRGLVRDLIKCGGMKGILVEQPKD-VIEENRQFKGEPPVFRVEKMF 536
W+V+ ++R L+ L + G+ + P++ +I ++R +
Sbjct: 476 DRWAVIAPQRNSHELRTLLDSLYRAASGMGLRIRSPQEFIIYDDR-------TGTYVRAM 528
Query: 537 ADVLKLSKRPSFLLCLLPERKNSDLYGPWKKKNLAEFGIVTQCIAPTRVNDQYL----TN 592
D ++ P +LCL+P N++ Y KK+ + + TQ + ++ L T
Sbjct: 529 DDCVRSD--PKLILCLVPN-DNAERYSSIKKRGYVDRAVPTQVVTLKTTKNRSLMSIATK 585
Query: 593 VLLKINAKLGGMNSWLGVEHSRSIPIVSKVPTLILGMDVSHGSPGQPDIPSIAAVVSSRK 652
+ +++N KLG W+ +P+ + +G D++ + + + A+++S
Sbjct: 586 IAIQLNCKLG-YTPWM-----IELPLSG---LMTIGFDIAKSTRDRKR--AYGALIASMD 634
Query: 653 WPLISKYRACVRTQGSKVEMIDNLFKPVSDKEDEGIIRELLLDFFHSSEERRPENIIIFR 712
S Y + V T+ S +++ N P+ I + L + H + P I+ +R
Sbjct: 635 LQQNSTYFSTV-TECSAFDVLANTLWPM--------IAKALRQYQHE-HRKLPSRIVFYR 684
Query: 713 DGVSESQFNEVLNVELSQIIEACKFLDENWN---PKFMVIVAQKNHHTKFFQPRSPDNVP 769
DGVS ++ E+ IIE K P+ IV ++ +T+FF + N P
Sbjct: 685 DGVSSGSLKQLFEFEVKDIIEKLKTEYARVQLSPPQLAYIVVTRSMNTRFFL--NGQNPP 742
Query: 770 PGTVVDSKICHPRNYDFYMCAHAGMIGTSRPTHYHVLLDEIGFSPDDLQELVHSLSYVYQ 829
PGT+VD I P YDFY+ + GT PT Y+VL +G SP+ +Q+L + + ++Y
Sbjct: 743 PGTIVDDVITLPERYDFYLVSQQVRQGTVSPTSYNVLYSSMGLSPEKMQKLTYKMCHLYY 802
Query: 830 R--STTAISVVKTYMQLLQSAMHTWLH 854
TT + V Y + L + + T LH
Sbjct: 803 NWSGTTRVPAVCQYAKKLATLVGTNLH 829
>GCC7_CAEEL (Q21770) Germ cell expressed protein R06C7.1
Length = 945
Score = 101 bits (251), Expect = 1e-20
Identities = 160/701 (22%), Positives = 282/701 (39%), Gaps = 95/701 (13%)
Query: 190 NYQEAIRVLDIILRQHSAKQ----GCLLVRQNFFHN------DPNNLNDVGGGVLSCKGL 239
N +E + L++ L QH ++ GC + +F N D + DVG G GL
Sbjct: 229 NNREYTQFLELALNQHCVRETNRFGCFEHGKVYFLNATEEGFDQRDCVDVGDGKQLYPGL 288
Query: 240 HSSFRTT-------QSGLSLNIDVSTTMIVRPGPVVDFLIENQNVRDPFS----LDWNKA 288
+ + Q+ SL ID + V+ L + +DP + + KA
Sbjct: 289 KKTIQFIEGPYGRGQNNPSLVIDGMKAAFHKEQTVIQKLFDITG-QDPSNGLNNMTREKA 347
Query: 289 KRTLKNLRITAKPSNQE--YKITGLSELSCKDQLFTMKKRGAVAGEDDTEEITVYDYFVH 346
+K L + +N++ +I G+ S F + D + ++ +Y+
Sbjct: 348 AAVIKGLDCYSTYTNRKRHLRIEGIFHESATKTRFELP---------DGKTCSIAEYYAD 398
Query: 347 RRKIDLQYSAG--LPCINVGKPKRPTYIPIELCSLISLQRYTKALSTSQRSSLVEKS-RQ 403
+ KI LQY + C + G Y P EL ++ QR T T +S K
Sbjct: 399 KYKISLQYPNANLVVCKDRGNNN---YFPAELMTVSRNQRVTIPQQTGNQSQKTTKECAV 455
Query: 404 KPVERMRVLSNALKASNYGSE-PMLRNCGISITSEFTQVDGRVLQAPRLKFGNEDFNPRN 462
P R R++ A N E +L GI + SE V R L L + +
Sbjct: 456 LPDVRQRMIITGKNAVNITLENELLVALGIKVYSEPLMVQARELDGKELVYQRSVMSDM- 514
Query: 463 GRWNFNNKKFVEPVSLGN----WSVVNFSARC---DVRGLVRDLIKCGGMKGILVEQPKD 515
G+W FV+P ++ + ++V N R DV LV I KG++++ P
Sbjct: 515 GKWRAPPGWFVKPATVPDLWAAYAVGNPGCRFSIGDVNQLVGMFIDSCKKKGMVIKPPC- 573
Query: 516 VIEENRQFKGEPPVFRVEKMFADVLKLSKRPSFLLCLLPERKNSDLYGPWKKKNLAEFGI 575
E ++ EK+ + K++ + ++ + L+ +K I
Sbjct: 574 ----------ETGLYSTEKIMTQLEKVAASKCKYVLMITDDAIVHLHKQYKALEQRTMMI 623
Query: 576 VTQCIAPTRVNDQY-------LTNVLLKINAKLGGMNSWLGVEHSRSIPIVSKVPTLILG 628
V Q + ++ N L N++ K N KLGG+N + + +S+ LI+G
Sbjct: 624 V-QDMKISKANAVVKDGKRLTLENIINKTNVKLGGLNYTVS-DAKKSMTDEQ----LIIG 677
Query: 629 MDVSHGSPGQPDIPSIAAVVSSRKWPLISKYRACVRTQGSKVEMIDNLFKPVSDKEDEGI 688
+ VS +P P+ + K L + + E + + S ++
Sbjct: 678 VGVS--AP-----PAGTKYMMDNKGHLNPQIIGFASNAVANHEFVGDFVLAPSGQDTMAS 730
Query: 689 IRELL---LDFFHSSEERRPENIIIFRDGVSESQFNEVLNVELSQIIEACKFLDENWNP- 744
I ++L +D F + + P+ III+R G SE +L E I + + ++
Sbjct: 731 IEDVLQNSIDLFEKNRKALPKRIIIYRSGASEGSHASILAYE----IPLARAIIHGYSKE 786
Query: 745 -KFMVIVAQKNHHTKFFQPR-------SPDNVPPGTVVDSKICHPRNYDFYMCAHAGMIG 796
K + IV K H +FF+ + + N+PPG V+D+ + +P F++ H + G
Sbjct: 787 IKLIFIVVTKEHSYRFFRDQLRSGGKATEMNIPPGIVLDNAVTNPACKQFFLNGHTTLQG 846
Query: 797 TSRPTHYHVLLDEIGFSPDDLQELVHSLSYVYQRSTTAISV 837
T++ Y VL D+ D L+EL +L + +Q + + S+
Sbjct: 847 TAKTPLYTVLADDCKAPMDRLEELTFTLCHHHQIVSLSTSI 887
>YQ53_CAEEL (Q09249) Hypothetical protein C16C10.3 in chromosome III
Length = 1032
Score = 94.7 bits (234), Expect = 9e-19
Identities = 122/573 (21%), Positives = 242/573 (41%), Gaps = 70/573 (12%)
Query: 307 KITGLSELSCKDQLFTMKKRGAVAGEDDTEEITVYDYFVHRRKIDLQYSAGLPCINVGKP 366
+++ ++E + ++ F MK + E+TV +YF+ + I L+Y LP + +
Sbjct: 414 RVSSIAENNAENTSFMMKD------DKGEREVTVAEYFLLQYNIKLKYPR-LPLVVSKRF 466
Query: 367 KRPTYIPIELCSLISLQRY-TKALSTSQRSSLVEKSRQKPVERMRVLSNALKAS-NYGSE 424
K ++ P+EL + QR +S + +S++ ++ P ++++ + L+ +
Sbjct: 467 KHESFFPMELLRIAPGQRIKVNKMSPTVQSAMTGRNASMPQHHVKLVQDILRDNLKLEQN 526
Query: 425 PMLRNCGISITS-EFTQVDGRVLQAPRLKFGNEDFNPRNGRWNFNNK-KFVEPVSLGNWS 482
+ GI + S E Q+ ++L ++KF + + P R F + KFVEP +
Sbjct: 527 KYMDAFGIKLMSTEPIQMTAKLLPPAQIKFKGQTYMPDMSRPAFRTQDKFVEPARIRKIG 586
Query: 483 VVNFSARCDVRGLVRDLIKCGGMKGILVEQPKDVIEENRQFKGEPPVFRVEKMFADVLK- 541
+V F C D C + + V +++R + +++K
Sbjct: 587 IVVFD-NCIQMRQAEDF--CDKLSNFCRDNGITVEKDSRDWSIRELNSSDSVAIQNLMKK 643
Query: 542 -LSKRPSFLLCLLPERKNSDLYGPWKKKNLAEFGIVTQCIAPTRVND--------QYLTN 592
L R L+ + E+K D++ K G+ T + V+ Q + N
Sbjct: 644 WLDDRVDILVGIAREKK-PDVHDILKYFE-ESIGLQTIQLCQQTVDKMMGGQGGRQTIDN 701
Query: 593 VLLKINAKLGGMNSWLGVEHS-RSIPIVSKVPTL---------ILGMDVSHGSP------ 636
V+ K N K GG N ++ + ++ R + S TL +G ++SHG+
Sbjct: 702 VMRKFNLKCGGTNFFVEIPNAVRGKAVCSNNETLRKKLLEHVQFIGFEISHGASRTLFDR 761
Query: 637 ------GQPDIPSIAAVVSSRKWPLISKYRACVRTQGSKVEMIDNLFKPVSDKEDEGIIR 690
G+P + ++ +++ + + + K++ +D F E
Sbjct: 762 SRSQMDGEPSVVGVSYSLTNSTQ--LGGFTYLQTQKEYKLQKLDEFFPKCVRSYKE---- 815
Query: 691 ELLLDFFHSSEERRPENIIIFRDGVSESQFNEVLNVELSQIIEACKFLDENWNPKFMVIV 750
HS + P I+I+R G E FN V E+ ++ + + P +VI+
Sbjct: 816 -------HS--KTLPTRIVIYRVGAGEGNFNRVKE-EVEEMRRTFDKIQPGYRPHLVVII 865
Query: 751 AQKNHHTKFFQP-----RSPD-NVPPGTVVDSKICHPRNYDFYMCAHAGMIGTSRPTHYH 804
AQ+ H + F R+ D N+P GT V++ + +F + + +IGT RP Y
Sbjct: 866 AQRASHARVFPSCISGNRATDQNIPSGTCVENVLTSYGYDEFILSSQTPLIGTVRPCKYT 925
Query: 805 VLLDEIGFSPDDLQELVHSLSYVYQRSTTAISV 837
+L+++ +S ++L L + ++ +Q S SV
Sbjct: 926 ILVNDAKWSKNELMHLTYFRAFGHQVSYQPPSV 958
Database: sprot
Posted date: Nov 25, 2004 10:54 AM
Number of letters in database: 59,974,054
Number of sequences in database: 164,201
Lambda K H
0.318 0.136 0.399
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 104,088,836
Number of Sequences: 164201
Number of extensions: 4637003
Number of successful extensions: 13418
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 23
Number of HSP's successfully gapped in prelim test: 7
Number of HSP's that attempted gapping in prelim test: 13247
Number of HSP's gapped (non-prelim): 41
length of query: 859
length of database: 59,974,054
effective HSP length: 119
effective length of query: 740
effective length of database: 40,434,135
effective search space: 29921259900
effective search space used: 29921259900
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 70 (31.6 bits)
Medicago: description of AC131455.7