BLASTP 2.2.2 [Dec-14-2001]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= AC131455.1 + phase: 0 
         (773 letters)

Database: sprot 
           164,201 sequences; 59,974,054 total letters

Searching..................................................done

                                                                   Score     E
Sequences producing significant alignments:                        (bits)  Value

MACF_MOUSE (Q9QXZ0) Microtubule-actin crosslinking factor 1 (Act...    49  5e-05
MYS_AEQIR (P24733) Myosin heavy chain, striated muscle                 43  0.003
BPS2_ACIAM (P32985) Protein bps2                                       43  0.003
GCC2_MOUSE (Q8CHG3) GRIP and coiled-coil domain-containing prote...    42  0.006
MYHB_RABIT (P35748) Myosin heavy chain, smooth muscle isoform (S...    42  0.008
EVPL_HUMAN (Q92817) Envoplakin (210 kDa paraneoplastic pemphigus...    40  0.018
DDL_HELPJ (Q9ZLA5) D-alanine--D-alanine ligase (EC 6.3.2.4) (D-a...    40  0.023
YDH1_SHV2C (P22575) Hypothetical 28.7 kDa protein in DHFR 3'regi...    40  0.031
CAV1_CAEEL (Q94051) Caveolin-1                                         40  0.031
RA50_PYRFU (P58301) DNA double-strand break repair rad50 ATPase        39  0.040
MYHB_HUMAN (P35749) Myosin heavy chain, smooth muscle isoform (S...    39  0.040
BA2B_CHICK (Q9DE13) Bromodomain adjacent to zinc finger domain 2...    39  0.040
VAC4_HELPY (Q48258) Vacuolating cytotoxin precursor                    39  0.052
VAC1_HELPY (Q48247) Vacuolating cytotoxin precursor                    39  0.052
YDOF_SCHPO (O13734) Hypothetical protein C15A10.15 in chromosome I     39  0.068
TEF_MOUSE (Q9JLC6) Thyrotroph embryonic factor                         39  0.068
VAC3_HELPY (Q48253) Vacuolating cytotoxin precursor                    38  0.089
TEF_RAT (P41224) Thyrotroph embryonic factor (Fragment)                38  0.089
TEF_PHOSU (P97516) Thyrotroph embryonic factor (Fragment)              38  0.089
TEF_HUMAN (Q10587) Thyrotroph embryonic factor                         38  0.089

>MACF_MOUSE (Q9QXZ0) Microtubule-actin crosslinking factor 1 (Actin
            cross-linking family 7)
          Length = 5327

 Score = 48.9 bits (115), Expect = 5e-05
 Identities = 65/324 (20%), Positives = 134/324 (41%), Gaps = 38/324 (11%)

Query: 469  ESKAEKTSTVDKTRAAVKDLHSRIRVAIHRIDSISKRIEELRDKELQPQLEELIEGLNRM 528
            ++K +     ++TR A K+L   +  A+ +    SK   EL + + +  ++ L++ +  +
Sbjct: 1639 QAKEQYEVLQERTRVAQKELEEAVTSALQQETEKSKAATELAENKRK--IDALLDWVGLL 1696

Query: 529  WEVMHECHKLQFQIMSASYNNSHARITM-----HSELRRQITAYLENELQFLSSSFTKWI 583
            W  + E H+L FQ  S+S   +  + T+     H ++  Q+   L+ + + + +   + +
Sbjct: 1697 WGHLRESHRLAFQEWSSSLELAMEKQTLAATDGHVDV-NQVPETLDRQYELMKARHQELL 1755

Query: 584  EAQKSYLQA-------INGWIHKCVPLQQKSVKRKRRPQSELLIQYGPPIYATCDVWLKK 636
              Q++++ A       ++   H   P +++ ++ K     EL  QY   + A  +  LK+
Sbjct: 1756 SQQQNFIVATQSAQSFLDQHSHNLTPEERQKLQEK---LGELKEQYAASL-ARSEAELKQ 1811

Query: 637  LGTLPVKDVVDSIKSLAADTARFLPYQDKNQGKEPHSHIGGESADGL-----LRDDISED 691
               L      D ++    D   F  +  +++ +    H GG S + L      +   SED
Sbjct: 1812 TQALR-----DELQKFLQDHKEFENWLQQSENELDSMHKGGSSPEALNSLLKRQGSFSED 1866

Query: 692  WISGFDRFRANLIRFLGQL------NSLSGSSVKMYREL-RQAIQEAKNNYHRLNSQSQN 744
             IS     R   +   GQ       N   G      R L  + +++A   Y  L+S+   
Sbjct: 1867 VISHKGDLR--FVTISGQKVLETENNFEEGQEPSATRNLVNEKLKDATERYTTLHSKCIR 1924

Query: 745  GHLNYQSYHGHHHNFESQDEQSQS 768
               +     G +  F+S  +  Q+
Sbjct: 1925 LGSHLSMLLGQYQQFQSSADSLQA 1948


>MYS_AEQIR (P24733) Myosin heavy chain, striated muscle
          Length = 1938

 Score = 43.1 bits (100), Expect = 0.003
 Identities = 93/442 (21%), Positives = 162/442 (36%), Gaps = 67/442 (15%)

Query: 200  EGGIPDLEDDEEKASSC-GSEGSRDSEDEFDEEPTAETLVQRFENLNRANNHVQENVLPV 258
            E  + +LED+ E+     G       + E D + T E +    E+L R    ++ENV   
Sbjct: 1025 EQALDELEDNLEREKKVRGDVEKAKRKVEQDLKSTQENV----EDLERVKRELEENVRRK 1080

Query: 259  KGDSVSEVELVSEKGNFPNSSPSKKLPMAALLPPEANKSTEKENHSENKVTPKNFFSSMK 318
            + +  S    + ++ N  +    K   + A +  E  +  E E ++  KV  K      +
Sbjct: 1081 EAEISSLNSKLEDEQNLVSQLQRKIKELQARIE-ELEEELEAERNARAKVE-KQRAELNR 1138

Query: 319  DIEVLFNRASDSGKEVPRMLEANKFHFRPIFQGKKDGSLASFICKACFSCGEDPSQVPEE 378
            ++E L  R  ++G      +E NK     + + ++D   AS   +A  S      Q    
Sbjct: 1139 ELEELGERLDEAGGATSAQIELNKKREAELLKIRRDLEEASLQHEAQISALRKKHQDAAN 1198

Query: 379  PAQNSVKYLTWHRTASSRSSSSKNPLDANSRENVEDLTNNLFDNSCMNAGSHASTLDRLH 438
               + V  L   +   S+    K  L     +    +T+N+ +  C              
Sbjct: 1199 EMADQVDQL---QKVKSKLEKDKKDLKREMDDLESQMTHNMKNKGC-------------- 1241

Query: 439  AWERKLYDEVKASEIVRKEYDAKCKILR-----NLESKAEKTSTVDKTRAAVKDLHSRIR 493
                        SE V K+++++   L      +  S  E  S   + +A   DL  ++ 
Sbjct: 1242 ------------SEKVMKQFESQMSDLNARLEDSQRSINELQSQKSRLQAENSDLTRQLE 1289

Query: 494  VAIHRIDSISKRIEELRD--KELQPQLEELIEGLNRMWEVMHECHKLQFQIMSASYNNSH 551
             A HR+  +SK   +L    ++ +  LEE     +++   +   H      M A      
Sbjct: 1290 DAEHRVSVLSKEKSQLSSQLEDARRSLEEETRARSKLQNEVRNMH----ADMDAIREQLE 1345

Query: 552  ARITMHSELRRQITAYLENELQFLSSSF-------TKWIEAQKSYL--------QAINGW 596
                  S+++RQ++    NE+Q   S F       T+ +E QK  L        Q     
Sbjct: 1346 EEQESKSDVQRQLSK-ANNEIQQWRSKFESEGANRTEELEDQKRKLLGKLSEAEQTTEAA 1404

Query: 597  IHKCVPLQQKSVKRKRRPQSEL 618
              KC  L+    K K R Q EL
Sbjct: 1405 NAKCSALE----KAKSRLQQEL 1422


>BPS2_ACIAM (P32985) Protein bps2
          Length = 582

 Score = 43.1 bits (100), Expect = 0.003
 Identities = 51/161 (31%), Positives = 82/161 (50%), Gaps = 24/161 (14%)

Query: 437 LHAWERKLYDEV--KASEIVRK--EYD------AKCKILRN-LESKAEKT-STVDKTRAA 484
           L+A  +K  DE+  K SEI +K  E D      +K K+ R+ LE++ E   ST+D     
Sbjct: 321 LYAGIKKEADELLSKKSEIEKKLKELDQISSEISKLKMSRSELENRIESVKSTIDDLERQ 380

Query: 485 VKDLHSRIR--VAIHRI----DSISKRIEELRDKELQPQLEELIEG-----LNRMWEVMH 533
            +++  R      I+R+    DSI+KRIEEL+ K+ + + E  I G     LN++ E   
Sbjct: 381 RREMEERFNRNAEIYRVYDINDSINKRIEELKKKKDEYEYELAINGIPSTILNKISEKQK 440

Query: 534 ECHKLQFQIMSASYNNSHARITMHSELRRQITAYLENELQF 574
           E  ++Q +++         R+T+  E   +I  YL  EL+F
Sbjct: 441 ELQEVQ-KMVDDLEKEYMRRLTIAREEFVKIANYLLKELEF 480


>GCC2_MOUSE (Q8CHG3) GRIP and coiled-coil domain-containing protein
           2 (Golgi coiled coil protein GCC185)
          Length = 1679

 Score = 42.0 bits (97), Expect = 0.006
 Identities = 79/372 (21%), Positives = 151/372 (40%), Gaps = 29/372 (7%)

Query: 390 HRTASSRSSSSKN-----PLDANSRENVEDLTNNLFDNSCMNAGSHASTLDRLHAWER-K 443
           +  AS  S  S+N       D ++ + V D    L D+       H+   D +      K
Sbjct: 298 NEVASDASPESQNCSVALQEDPSAEQTVCDKVRQLEDSLKELESQHSILKDEVTYMNNLK 357

Query: 444 LYDEVKAS----EIVRKEYDAKCKILRNLESKAEKTSTVDKTRAAVKDLHSRIRVAIHRI 499
           L  E+ A     E   +  D + KI   L +K E+   V+K +   +DL+ ++  A+ + 
Sbjct: 358 LKLEMDAQHIKDEFFHEREDLEFKINELLLAKEEQGYVVEKLKYEREDLNRQLCCAVEQH 417

Query: 500 DSISKRIEELRDKELQPQLEELIEGLNR-MWEVMHECHKLQFQIMSASYNNSHARITMHS 558
           +   +R++E   KE+    E  I G  +    +M E   L+ Q  +  +      + ++ 
Sbjct: 418 NKEIQRLQEHHQKEVSELSETFISGSEKEKLALMFEIQGLKEQCENLQHEKQ--EVVLNY 475

Query: 559 ELRRQITAYLENELQFLSSSFTKWIEAQKSYLQAINGWIHKCVPLQQKSVKRKRRPQSEL 618
           E  R++   L+ EL   +   ++  E  K   QA +  +H+   LQQK   R    + + 
Sbjct: 476 ESLREMMEILQTELGESAGKISQEFETMKQQ-QASD--VHE---LQQK--LRSAFNEKDA 527

Query: 619 LIQYGPPIYATCDVWLKKLGTLPVKDVVDSIKSLAADTARFLPYQDK-----NQGKEPHS 673
           L++    +    +  L +   +P  ++  +IK+L AD + +L    +      + +   S
Sbjct: 528 LLETVNRLQGENEKLLSQQELVP--ELESTIKNLQADNSMYLASLGQKDTMLQELEAKIS 585

Query: 674 HIGGESADGLLRDDISEDWISGFDRFRANLIRFLGQLNSLSGSSVKMYRELRQAIQEAKN 733
            +  E  D + +   S + +    +      R   +L   +G + +   ELRQ + E   
Sbjct: 586 SLAKEKDDFISKIKTSHEEMDDLHQKWEREQRLSVELREAAGQAAQHNSELRQRVSELTG 645

Query: 734 NYHRL-NSQSQN 744
               L   +SQN
Sbjct: 646 KLDELVREKSQN 657


>MYHB_RABIT (P35748) Myosin heavy chain, smooth muscle isoform (SMMHC)
          Length = 1972

 Score = 41.6 bits (96), Expect = 0.008
 Identities = 101/422 (23%), Positives = 170/422 (39%), Gaps = 76/422 (18%)

Query: 393  ASSRSSSSKNPLDANSRENVEDLTNNLFDNSCMNAGSHASTLDRLHAWER----KLYDEV 448
            A  +   +KN L     + V DL N        N        D+L A E+    K  DE 
Sbjct: 1414 AYDKLEKTKNRLQQELDDLVVDLDNQR--QLVSNLEKKQKKFDQLLAEEKNISSKYADER 1471

Query: 449  KASEIVRKEYDAKCKILRN-----LESKAEKTSTVDKTRAAVKDLHSR---IRVAIHRID 500
              +E   +E + K   L       LE+K E   T    +A ++DL S    +   +H ++
Sbjct: 1472 DRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELE 1531

Query: 501  SISKRIEELRDKELQPQLEEL------IEGLNRMWEVMHECHKLQFQIMSASYNNSHARI 554
              SKR  E + +E++ QLEEL       E      EV  +  K+QF+       +  AR 
Sbjct: 1532 K-SKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKVQFE------RDLQARD 1584

Query: 555  TMHSELRRQITAYL---------ENELQFLSSSFTKWIEAQKSYLQ-----AING---WI 597
              + E RRQ+   L         E + + L+++  K +E     L+     AI G    I
Sbjct: 1585 EQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAI 1644

Query: 598  HKCVPLQ------QKSVKRKRRPQSELLIQYGPPIYATCDVWLKKLGTLPVKDVVDSIKS 651
             + + LQ      Q+ ++  R  + E        I+AT     KK  +L   D++   + 
Sbjct: 1645 KQLLKLQAQMKDFQRELEDARASRDE--------IFATAKENEKKAKSLEA-DLMQLQED 1695

Query: 652  L-AADTARFLPYQDKNQ-GKEPHSHIGGESADGLLRDDISEDWISGFDRFRANLIRFLGQ 709
            L AA+ AR     +K +  +E  S + G +A   L+D+          R  A + +   +
Sbjct: 1696 LAAAERARKQADLEKEELAEELASSLSGRNA---LQDEKR--------RLEARIAQLEEE 1744

Query: 710  LNSLSGSSVKMYRELRQAIQEAKNNYHRLNSQSQNGHLNYQSYHGHHHNFESQDEQSQSQ 769
            L    G+   M   +R+A Q+A+   + L ++      N  +        E Q+++ +S+
Sbjct: 1745 LEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESA----RQQLERQNKELKSK 1800

Query: 770  SQ 771
             Q
Sbjct: 1801 LQ 1802


>EVPL_HUMAN (Q92817) Envoplakin (210 kDa paraneoplastic pemphigus
           antigen) (p210) (210 kDa cornified envelope precursor)
          Length = 2033

 Score = 40.4 bits (93), Expect = 0.018
 Identities = 42/195 (21%), Positives = 91/195 (46%), Gaps = 13/195 (6%)

Query: 326 RASDSGKEVPRMLEANKFHFRPIFQGKKDGSLASFICKACFSCGEDPSQVPEEPAQNSVK 385
           R SD   ++   L+A K   + I   ++D + AS + +A  +  +D  ++  +  + S++
Sbjct: 775 RPSDGPSQIAYKLQAQKRLTQEIQSRERDRATASHLSQALQAALQD-YELQADTYRCSLE 833

Query: 386 YLTWHRTASSRSSSSKNPLDANSRENVEDLTNNLFDNSCMNAGSHASTLDRLHAWERKLY 445
                   +   S+ K P  A  +E+++    NL       A +    L +L  + RK+ 
Sbjct: 834 -------PTLAVSAPKRPRVAPLQESIQAQEKNLAKAYTEVAAAQQQLLQQLE-FARKML 885

Query: 446 DEVKASEIVRKEYDAKCKILRNLESKAEKTSTVDKTRAAVKDLHSRIRVAIHRIDSISKR 505
           ++ + SE +R+ +DAK    +  ES A+     +  +A +++   R+    H +++   +
Sbjct: 886 EKKELSEDIRRTHDAK----QGSESPAQAGRESEALKAQLEEERKRVARVQHELEAQRSQ 941

Query: 506 IEELRDKELQPQLEE 520
           + +LR +    +LEE
Sbjct: 942 LLQLRTQRPLERLEE 956


>DDL_HELPJ (Q9ZLA5) D-alanine--D-alanine ligase (EC 6.3.2.4)
           (D-alanylalanine synthetase) (D-Ala-D-Ala ligase)
          Length = 347

 Score = 40.0 bits (92), Expect = 0.023
 Identities = 28/79 (35%), Positives = 44/79 (55%), Gaps = 5/79 (6%)

Query: 347 PIFQGKKDGSLASFICKA--CFSCGEDPSQVPEEPAQNSVKYLTWHRTASSRSSSSKNPL 404
           P  QG K+ +LA    K   CFS  E+P++  +E      KYL + RT + +++ S N L
Sbjct: 208 PFIQGVKEYNLAGCKIKKGFCFSYVEEPNK--QEFLDFKQKYLDFSRTKAPKANLS-NAL 264

Query: 405 DANSRENVEDLTNNLFDNS 423
           +   +EN + L N+LFD +
Sbjct: 265 EEQLKENFKKLYNDLFDGA 283


>YDH1_SHV2C (P22575) Hypothetical 28.7 kDa protein in DHFR 3'region
           (ORF1)
          Length = 256

 Score = 39.7 bits (91), Expect = 0.031
 Identities = 49/215 (22%), Positives = 83/215 (37%), Gaps = 24/215 (11%)

Query: 209 DEEKASSCGSEGSRDSEDE-FDEEPTAETLVQRFENLNRANNHVQENVLPVKGDSVSEVE 267
           DEEK SSC  E +  S     D  P    +    +N +R  + +Q +          E+E
Sbjct: 22  DEEKLSSCSEETTNTSSSSGSDHVPVPIEVNVIIQNSSRTEDELQNS---------KEIE 72

Query: 268 LVSEKGNFPNSSPSKKLPMAALLPPEANKSTEKENHSENKV-TPKNFFSSMKDIEVLFNR 326
           L   +G   + S     P ++    +A+   E+   +E     P+N  +++  +   F  
Sbjct: 73  LTGFQGKLSSCSEETTAPSSSYSSKQASVFIEENGDNETSTYRPQNVLTNLNSLYTTFED 132

Query: 327 ASDSGKEVPRM----LEANKFHFRPIFQGKKDGSLASFICKACFSCGEDPSQVPEEPAQN 382
           A   GK + R     L++    + P F+  K          A +  G     +P  PA  
Sbjct: 133 ARAQGKGMVRHKSEDLQSFLEKYPPDFRKPKRD------LSATWDPGMPTPPLPPRPANL 186

Query: 383 SVKYLTWHRTASSRSSSSKNPLD--ANSRENVEDL 415
             +  +  R    + S+ K P +  AN R  V+DL
Sbjct: 187 GERQASTVR-LHVKESNCKQPRERKANERNIVKDL 220


>CAV1_CAEEL (Q94051) Caveolin-1
          Length = 235

 Score = 39.7 bits (91), Expect = 0.031
 Identities = 29/89 (32%), Positives = 40/89 (44%), Gaps = 1/89 (1%)

Query: 178 PVDHQFSFQEPKGMPHHIGNAEEGGIP-DLEDDEEKASSCGSEGSRDSEDEFDEEPTAET 236
           P  + F+F + K  P    N EEGG P D    E+K   C     +  E E  EE  A  
Sbjct: 40  PKKNWFTFGKKKAAPTDETNIEEGGAPGDEPVKEKKEKKCWWSRCQKGEGEQKEENIAIG 99

Query: 237 LVQRFENLNRANNHVQENVLPVKGDSVSE 265
           +     + N  NNHVQ N   + G++ S+
Sbjct: 100 VDLVNRDANSMNNHVQLNFEDIFGEADSQ 128


>RA50_PYRFU (P58301) DNA double-strand break repair rad50 ATPase
          Length = 882

 Score = 39.3 bits (90), Expect = 0.040
 Identities = 31/117 (26%), Positives = 58/117 (49%), Gaps = 13/117 (11%)

Query: 434 LDRLHAWERKLYDEVKASEIVRKEYDAKCKILRNLESKAEKTSTVDKTRAAVKDLHSRIR 493
           L++L   E++L ++VK    ++K+ DA   +        +K   ++K    V++L     
Sbjct: 274 LEKLKEKEKELEEQVKEITSIKKDVDAYLALKEFKNEYLDKKYKIEKELTRVEEL----- 328

Query: 494 VAIHRIDSISKRIEELRDKELQPQL--EELIEGLNRMWEVMHECHKLQFQIMSASYN 548
                I+ I KRIEEL +KE + +    E  E LN++  ++ + H+L  +I +   N
Sbjct: 329 -----INEIQKRIEELNEKESEKEKLENEKKEILNKL-AILEKDHQLYEEIKAKKEN 379


>MYHB_HUMAN (P35749) Myosin heavy chain, smooth muscle isoform (SMMHC)
          Length = 1972

 Score = 39.3 bits (90), Expect = 0.040
 Identities = 94/415 (22%), Positives = 168/415 (39%), Gaps = 66/415 (15%)

Query: 393  ASSRSSSSKNPLDANSRENVEDLTNNLFDNSCMNAGSHASTLDRLHAWER----KLYDEV 448
            A  +   +KN L     + V DL N        N        D+L A E+    K  DE 
Sbjct: 1414 AYDKLEKTKNRLQQELDDLVVDLDNQR--QLVSNLEKKQRKFDQLLAEEKNISSKYADER 1471

Query: 449  KASEIVRKEYDAKCKILRN-----LESKAEKTSTVDKTRAAVKDLHSR---IRVAIHRID 500
              +E   +E + K   L       LE+K E   T    +A ++DL S    +   +H ++
Sbjct: 1472 DRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELE 1531

Query: 501  SISKRIEELRDKELQPQLEEL------IEGLNRMWEVMHECHKLQFQIMSASYNNSHARI 554
              SKR  E + +E++ QLEEL       E      EV  +  K QF+       +  AR 
Sbjct: 1532 K-SKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFE------RDLQARD 1584

Query: 555  TMHSELRRQITAYL---------ENELQFLSSSFTKWIEAQKSYLQAINGWIHKCVPLQQ 605
              + E RRQ+   L         E + + L+++  K +E     L+ +       +  ++
Sbjct: 1585 EQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGD---LKDLELQADSAIKGRE 1641

Query: 606  KSVKRKRRPQSEL---------LIQYGPPIYATCDVWLKKLGTLPVKDVVDSIKSL-AAD 655
            +++K+ R+ Q+++                I+AT     KK  +L   D++   + L AA+
Sbjct: 1642 EAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEA-DLMQLQEDLAAAE 1700

Query: 656  TARFLPYQDKNQ-GKEPHSHIGGESADGLLRDDISEDWISGFDRFRANLIRFLGQLNSLS 714
             AR     +K +  +E  S + G +A   L+D+          R  A + +   +L    
Sbjct: 1701 RARKQADLEKEELAEELASSLSGRNA---LQDEKR--------RLEARIAQLEEELEEEQ 1749

Query: 715  GSSVKMYRELRQAIQEAKNNYHRLNSQSQNGHLNYQSYHGHHHNFESQDEQSQSQ 769
            G+   M   +R+A Q+A+   + L ++      N  +        E Q+++ +S+
Sbjct: 1750 GNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESA----RQQLERQNKELRSK 1800


>BA2B_CHICK (Q9DE13) Bromodomain adjacent to zinc finger domain 2B
           (Extracellular matrix protein F22)
          Length = 2130

 Score = 39.3 bits (90), Expect = 0.040
 Identities = 90/416 (21%), Positives = 157/416 (37%), Gaps = 52/416 (12%)

Query: 197 NAEEGGIPDLEDDEEKASSCGSEGSRDSEDEFDEEPTAETLVQRFENLNRANNHVQENVL 256
           N ++    D ++D+E   S  S+   DS  E D + + +   +  ++ + ++   +    
Sbjct: 557 NDDDDDDEDEDEDDEDDDSDDSQSESDSNSESDTDGSEDEDDEDDKDQDESDTDTEGEKT 616

Query: 257 PVK----GDSVSEVELVSEKGNFPNSSPSKKLPMAA--LLPPEANKSTEKENHSENKVTP 310
           P+K    G S+    +     + P +    K P +A   L PE   +      + + +TP
Sbjct: 617 PLKLKKTGSSIKSSSIGPVAHSTPLNLQVAKTPSSAPSALCPETQPAVFL-GTTPSTLTP 675

Query: 311 KNFFSSMKDIEVLFNRASDSGKEVPRMLEANKFHFRPIFQGKKDGSLASFICKACFSCGE 370
            +     K   V   R      E     E    +    F G+  G +A F       CG+
Sbjct: 676 SSHCGISKRRRVTDERELRVPLEYGWQRETRIRN----FGGRLQGEVAYFA-----PCGK 726

Query: 371 DPSQVPEEPAQNSVKYLTW-----------HRTASSRSSSSKNPLDANSRENVEDLTNNL 419
              Q PE      VK + W            R    R     NP   +SRE         
Sbjct: 727 KLRQYPE-----VVKGVQWCLLKEEEVVPCIRAMEGRRGRPPNPDRQHSREESRMRRRK- 780

Query: 420 FDNSCMNAGSHASTLDRLHAWERKLYDEVKASEIVRKEYDAKCKILRNLESK-----AEK 474
                 N GS     + L + + KL  +++A EI R+   A+ K+LR L+ +     A++
Sbjct: 781 --GRPPNVGS----TEFLDSTDAKLLRKLQAQEIARQA--AQIKLLRKLQKQEQARAAKE 832

Query: 475 TSTVDKTRAAVKDLHSRIRVAIHRIDSISKRIEELR-DKELQPQLEELIEGLNRMWEVMH 533
                   AA +    + ++ I +     KRI+++R +KEL+ Q  +++E   +  E   
Sbjct: 833 AKKQQAIMAAEEKRKQKEQIKIMKQQEKIKRIQQIRMEKELRAQ--QILEAKKKKKEEAA 890

Query: 534 ECHKLQFQ--IMSASYNNSHARITMHSELRRQITAYLENELQFLSSSFTKWIEAQK 587
               L+ +  I         A +  H EL R     +E E +       K +EA+K
Sbjct: 891 NAKLLEAEKRIKEKEMRRQQAVLLKHQELERH-RLDMERERRRQHMMLMKAMEARK 945


>VAC4_HELPY (Q48258) Vacuolating cytotoxin precursor
          Length = 1291

 Score = 38.9 bits (89), Expect = 0.052
 Identities = 50/212 (23%), Positives = 90/212 (41%), Gaps = 21/212 (9%)

Query: 384  VKYLTWHRTASSRSSSSKNPLDANSRENVEDLTNNLFDNSCMNAGSHASTLDRLHA---- 439
            +K   + R +++ +  + N  D  + E+V +L N   D   + A S A   D L      
Sbjct: 859  IKNAPFARYSATPNLVAINQHDFGTIESVFELANRSNDIDTLYANSGAQGRDLLQTLLID 918

Query: 440  -----WERKLYDEVKASEIVRKEYDAKCKILRNLESKAEKTS---TVDKTRAAVKDLHSR 491
                 + R + D   A+EI  K+ +     L N+ S   KTS   T+  + A +  L+SR
Sbjct: 919  SHDAGYARTMIDATSANEIT-KQLNTATTTLNNIASLEHKTSGLQTLSLSNAMI--LNSR 975

Query: 492  I----RVAIHRIDSISKRIEELRDKELQPQLEELIEGLNRMWEVMHECHKLQFQIMSASY 547
            +    R   + IDS +KR++ L+D+     LE   E L +      +   +    +  + 
Sbjct: 976  LVNLSRRHTNHIDSFAKRLQALKDQRF-ASLESAAEVLYQFAPKYEKPTNVWANAIGGTS 1034

Query: 548  NNSHARITMHSELRRQITAYLENELQFLSSSF 579
             NS    +++      + AYL  E++ +   F
Sbjct: 1035 LNSGGNASLYG-TSAGVDAYLNGEVEAIVGGF 1065


>VAC1_HELPY (Q48247) Vacuolating cytotoxin precursor
          Length = 1296

 Score = 38.9 bits (89), Expect = 0.052
 Identities = 38/128 (29%), Positives = 60/128 (46%), Gaps = 19/128 (14%)

Query: 402  NPLDANSRENVEDLTNNLFDNSCMNAGSHASTLDRLHA---------WERKLYDEVKASE 452
            N  D  + E+V +L N   D   + A S A   D L           + RK+ D   A+E
Sbjct: 882  NQHDFGTIESVFELANRSKDIDTLYANSGAQGRDLLQTLLIDSHDAGYARKMIDATSANE 941

Query: 453  IVRKEYDAKCKILRNLESKAEKTS---TVDKTRAAVKDLHSRI----RVAIHRIDSISKR 505
            I  K+ +     L N+ S   KTS   T+  + A +  L+SR+    R   + IDS +KR
Sbjct: 942  IT-KQLNTATTTLNNIASLEHKTSGLQTLSLSNAMI--LNSRLVNLSRRHTNHIDSFAKR 998

Query: 506  IEELRDKE 513
            ++ L+D++
Sbjct: 999  LQALKDQK 1006


>YDOF_SCHPO (O13734) Hypothetical protein C15A10.15 in chromosome I
          Length = 647

 Score = 38.5 bits (88), Expect = 0.068
 Identities = 37/162 (22%), Positives = 64/162 (38%), Gaps = 13/162 (8%)

Query: 142 SSGIAQNGSRMSETEAFEDSSVPDGTPQWDFFGLFNPVDHQFSFQEPKGMPHHIGNAEEG 201
           S  +  N     E    E+ S+ D  PQ          +H++    PK + + I N    
Sbjct: 204 SKPVNNNNEDRVEAVTSENKSI-DSAPQ--------EKNHEYEIVSPKSLSNKINNQAAA 254

Query: 202 GIPDLEDDEEKASSCGSEGSRDSEDEFDEEPTAETLVQRFENLNRANNHVQENVLPVKGD 261
                ED+    +   +EGS+  E  F     ++T++Q      + +  +Q   + +   
Sbjct: 255 QRRTEEDNANGVAQEENEGSQ--EAHFHSRIQSDTVIQSTPTKRKWDVDIQNKQINLASA 312

Query: 262 SVSEVELVSEKGNFPNSSPSKKLPMAALLPPEANKSTEKENH 303
           + +    VSE  + PN + S  L  A LL   +NKS    +H
Sbjct: 313 ATNVTGYVSETDSRPNRANS--LDSAVLLVQSSNKSNRNGHH 352


>TEF_MOUSE (Q9JLC6) Thyrotroph embryonic factor
          Length = 301

 Score = 38.5 bits (88), Expect = 0.068
 Identities = 41/155 (26%), Positives = 68/155 (43%), Gaps = 19/155 (12%)

Query: 96  GETHSFYTTPSPPSSSK--FHANHMKFGSFSSKKVEEKPPVPVIATVTSSGIAQNGSRMS 153
           G+  +  +T SPPSSS   F  +     + SS + E + P P+  +     +  N     
Sbjct: 128 GKESASSSTASPPSSSTAIFQPSETVSSTESSLEKERETPSPIDPSCVEVDVNFN----P 183

Query: 154 ETEAFEDSSVPDGTPQWDFFGLFNPVDHQFSFQEPKGMPHHIGNAEEGGIPDLEDDEE-- 211
           +      SSVP G        LFNP  H+F+ ++ K  P  I  A++  +PD + DE+  
Sbjct: 184 DPADLVLSSVPGGE-------LFNPRKHRFAEEDLKPQP-MIKKAKKVFVPDEQKDEKYW 235

Query: 212 ---KASSCGSEGSRDSEDEFDEEPTAETLVQRFEN 243
              K ++  ++ SRD+    + + T        EN
Sbjct: 236 TRRKKNNVAAKRSRDARRLKENQITIRAAFLEKEN 270


>VAC3_HELPY (Q48253) Vacuolating cytotoxin precursor
          Length = 1310

 Score = 38.1 bits (87), Expect = 0.089
 Identities = 47/194 (24%), Positives = 83/194 (42%), Gaps = 21/194 (10%)

Query: 402  NPLDANSRENVEDLTNNLFDNSCMNAGSHASTLDRLHA---------WERKLYDEVKASE 452
            N  D  + E+V +L N   D   + A S A   D L           + R + D   A+E
Sbjct: 897  NQHDFGTIESVFELANRSSDIDTLYANSGAQGRDLLQTLLIDSHDAGYARTMIDATSANE 956

Query: 453  IVRKEYDAKCKILRNLESKAEKTS---TVDKTRAAVKDLHSRI----RVAIHRIDSISKR 505
            I + + +A    L N+ S   KTS   T+  + A +  L+SR+    R   + IDS +KR
Sbjct: 957  ITQ-QLNAATTTLNNIASLEHKTSGLQTLSLSNAMI--LNSRLVNLSRKHTNHIDSFAKR 1013

Query: 506  IEELRDKELQPQLEELIEGLNRMWEVMHECHKLQFQIMSASYNNSHARITMHSELRRQIT 565
            ++ L+D+     LE   E L +      +   +    +  +  N+ +  +++      + 
Sbjct: 1014 LQALKDQRF-ASLESAAEVLYQFAPKYEKPTNVWANAIGGTSLNNGSNASLYG-TSAGVD 1071

Query: 566  AYLENELQFLSSSF 579
            AYL  E++ +   F
Sbjct: 1072 AYLNGEVEAIVGGF 1085


>TEF_RAT (P41224) Thyrotroph embryonic factor (Fragment)
          Length = 271

 Score = 38.1 bits (87), Expect = 0.089
 Identities = 41/155 (26%), Positives = 67/155 (42%), Gaps = 19/155 (12%)

Query: 96  GETHSFYTTPSPPSSSK--FHANHMKFGSFSSKKVEEKPPVPVIATVTSSGIAQNGSRMS 153
           G+  +  +T SPPSSS   F  +     + SS + E + P P+        +  N     
Sbjct: 98  GKESASSSTASPPSSSTAIFQPSETVSSTESSLEKERETPSPIDPNCVEVDVNFN----P 153

Query: 154 ETEAFEDSSVPDGTPQWDFFGLFNPVDHQFSFQEPKGMPHHIGNAEEGGIPDLEDDEE-- 211
           +      SSVP G        LFNP  H+F+ ++ K  P  I  A++  +PD + DE+  
Sbjct: 154 DPADLVLSSVPGGE-------LFNPRKHKFAEEDLKPQP-MIKKAKKVFVPDEQKDEKYW 205

Query: 212 ---KASSCGSEGSRDSEDEFDEEPTAETLVQRFEN 243
              K ++  ++ SRD+    + + T        EN
Sbjct: 206 TRRKKNNVAAKRSRDARRLKENQITIRAAFLEKEN 240


>TEF_PHOSU (P97516) Thyrotroph embryonic factor (Fragment)
          Length = 221

 Score = 38.1 bits (87), Expect = 0.089
 Identities = 41/155 (26%), Positives = 67/155 (42%), Gaps = 19/155 (12%)

Query: 96  GETHSFYTTPSPPSSSK--FHANHMKFGSFSSKKVEEKPPVPVIATVTSSGIAQNGSRMS 153
           G+  +  +T SPPSSS   F  +     + SS + E + P P+        +  N     
Sbjct: 70  GKESASSSTASPPSSSTAVFQPSETVSSTESSLEKERETPSPIDPNCVEVDVNFN----P 125

Query: 154 ETEAFEDSSVPDGTPQWDFFGLFNPVDHQFSFQEPKGMPHHIGNAEEGGIPDLEDDEE-- 211
           +      SSVP G        LFNP  H+F+ ++ K  P  I  A++  +PD + DE+  
Sbjct: 126 DPADLVLSSVPGGE-------LFNPRKHKFAEEDLKPQP-MIKKAKKVFVPDEQKDEKYW 177

Query: 212 ---KASSCGSEGSRDSEDEFDEEPTAETLVQRFEN 243
              K ++  ++ SRD+    + + T        EN
Sbjct: 178 TRRKKNNVAAKRSRDARRLKENQITIRAAFLEKEN 212


>TEF_HUMAN (Q10587) Thyrotroph embryonic factor
          Length = 303

 Score = 38.1 bits (87), Expect = 0.089
 Identities = 41/155 (26%), Positives = 67/155 (42%), Gaps = 19/155 (12%)

Query: 96  GETHSFYTTPSPPSSSK--FHANHMKFGSFSSKKVEEKPPVPVIATVTSSGIAQNGSRMS 153
           G+  +  +T SPPSSS   F  +     + SS + E + P P+        +  N     
Sbjct: 130 GKESASSSTASPPSSSTAIFQPSETVSSTESSLEKERETPSPIDPNCVEVDVNFN----P 185

Query: 154 ETEAFEDSSVPDGTPQWDFFGLFNPVDHQFSFQEPKGMPHHIGNAEEGGIPDLEDDEE-- 211
           +      SSVP G        LFNP  H+F+ ++ K  P  I  A++  +PD + DE+  
Sbjct: 186 DPADLVLSSVPGGE-------LFNPRKHKFAEEDLKPQP-MIKKAKKVFVPDEQKDEKYW 237

Query: 212 ---KASSCGSEGSRDSEDEFDEEPTAETLVQRFEN 243
              K ++  ++ SRD+    + + T        EN
Sbjct: 238 TRRKKNNVAAKRSRDARRLKENQITIRAAFLEKEN 272


  Database: sprot
    Posted date:  Nov 25, 2004 10:54 AM
  Number of letters in database: 59,974,054
  Number of sequences in database:  164,201
  
Lambda     K      H
   0.312    0.128    0.365 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 90,046,418
Number of Sequences: 164201
Number of extensions: 3888074
Number of successful extensions: 12109
Number of sequences better than 10.0: 165
Number of HSP's better than 10.0 without gapping: 10
Number of HSP's successfully gapped in prelim test: 157
Number of HSP's that attempted gapping in prelim test: 11905
Number of HSP's gapped (non-prelim): 315
length of query: 773
length of database: 59,974,054
effective HSP length: 118
effective length of query: 655
effective length of database: 40,598,336
effective search space: 26591910080
effective search space used: 26591910080
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 70 (31.6 bits)