BLAST2 result
BLASTP 2.2.2 [Dec-14-2001]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= AC127429.3 - phase: 0 /pseudo
(423 letters)
Database: sprot
164,201 sequences; 59,974,054 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
FMO5_RABIT (Q04799) Dimethylaniline monooxygenase [N-oxide-formi... 89 3e-17
FMO5_MOUSE (P97872) Dimethylaniline monooxygenase [N-oxide-formi... 88 5e-17
FMO3_MACMU (Q8SPQ7) Dimethylaniline monooxygenase [N-oxide-formi... 87 6e-17
FMO2_MACMU (Q28505) Dimethylaniline monooxygenase [N-oxide-formi... 85 3e-16
FMO5_HUMAN (P49326) Dimethylaniline monooxygenase [N-oxide-formi... 85 4e-16
FMO4_HUMAN (P31512) Dimethylaniline monooxygenase [N-oxide-formi... 85 4e-16
FMO4_RABIT (P36367) Dimethylaniline monooxygenase [N-oxide-formi... 84 5e-16
Y916_MYCBO (P64746) Probable monooxygenase Mb0916 (EC 1.14.13.-) 84 7e-16
Y892_MYCTU (P64745) Probable monooxygenase Rv0892/MT0916 (EC 1.1... 84 7e-16
FMO6_HUMAN (O60774) Putative dimethylaniline monooxygenase [N-ox... 84 7e-16
FMO2_PANTR (Q8HZ70) Dimethylaniline monooxygenase [N-oxide-formi... 84 7e-16
FMO2_GORGO (Q8HZ69) Dimethylaniline monooxygenase [N-oxide-formi... 84 7e-16
FMO2_HUMAN (Q99518) Dimethylaniline monooxygenase [N-oxide-formi... 83 1e-15
FMO3_HUMAN (P31513) Dimethylaniline monooxygenase [N-oxide-formi... 83 2e-15
FMO3_PANTR (Q7YS44) Dimethylaniline monooxygenase [N-oxide-formi... 81 4e-15
FMO5_CAVPO (P49109) Dimethylaniline monooxygenase [N-oxide-formi... 80 1e-14
FMO1_HUMAN (Q01740) Dimethylaniline monooxygenase [N-oxide-formi... 79 3e-14
FMO1_PIG (P16549) Dimethylaniline monooxygenase [N-oxide-forming... 78 5e-14
FMO3_MOUSE (P97501) Dimethylaniline monooxygenase [N-oxide-formi... 77 8e-14
FMO2_CAVPO (P36366) Dimethylaniline monooxygenase [N-oxide-formi... 76 2e-13
>FMO5_RABIT (Q04799) Dimethylaniline monooxygenase [N-oxide-forming]
5 (EC 1.14.13.8) (Hepatic flavin-containing
monooxygenase 5) (FMO 5) (Dimethylaniline oxidase 5)
(FMO 1C1) (FMO form 3)
Length = 532
Score = 88.6 bits (218), Expect = 3e-17
Identities = 92/370 (24%), Positives = 157/370 (41%), Gaps = 58/370 (15%)
Query: 44 IVGAGPSGLAVAAYLKQKGVPSLILERSNCIASLWKLKT---------YDRLRLHLPKQV 94
++GAG SGLA ++G+ + ER++ I LW+ + Y + ++ K++
Sbjct: 7 VIGAGASGLACIKCCLEEGLEPVCFERTDDIGGLWRFQESPDEGRASIYKSVIINTSKEM 66
Query: 95 CELPLMEFPSGFPTYPTKQQFIEYLESYSKNFDIRPW--FNETVMHAEFD---ATLGFWR 149
P FP + Q +EY Y+K F + + F TV + +T G W
Sbjct: 67 MCFSDYPIPDHFPNFMHNSQVLEYFRMYAKEFGLLKYIQFKTTVCSVKKRPDFSTSGQWE 126
Query: 150 VRSEGKAGMVTEFVCRWLIVATGENAEAVVP--EIEGVDEFVGSIRHTSLYKSGEEFRGK 207
V +E + G V ++V TG + A +P G+++F G H+ YK+ E+F GK
Sbjct: 127 VLTECE-GKKESAVFDGVLVCTGHHTSAHLPLESFPGIEKFKGQYLHSRDYKNPEKFTGK 185
Query: 208 KVLVVGCGNSGMEVCLDLCNHDAAPSIVVRDSPTKRYAGKINFWVVHVV----------- 256
+V+V+G GNSG ++ +++ +H A + T+R A W+++ V
Sbjct: 186 RVIVIGIGNSGGDLAVEI-SHTAKQVFL----STRRGA-----WIMNRVGDHGYPIDILL 235
Query: 257 ----AQVATRATGGSHPSHCVMVNARQHRTVRFGSASVGSP*TQKTVWKDTGPRCGCPCQ 312
+Q + TG + + + Q RF A G + + + P
Sbjct: 236 SSRFSQFLKKITGETIANSFLERKMNQ----RFDHAMFGLKPKHRALSQHPTVNDDLP-- 289
Query: 313 D*KRRHQGIKRLKRYTVEFA-------DGSTE-NFDAIILATGYKSNVPYWLKDKGMFSK 364
R G ++K EF DGS E + DA+I ATGY + P+ +
Sbjct: 290 --NRIISGSVKIKGNVKEFTETAAIFEDGSREDDIDAVIFATGYSFSFPFLEDSVKVVKN 347
Query: 365 EDGYPRKPFP 374
+ +K FP
Sbjct: 348 KVSLYKKVFP 357
>FMO5_MOUSE (P97872) Dimethylaniline monooxygenase [N-oxide-forming]
5 (EC 1.14.13.8) (Hepatic flavin-containing
monooxygenase 5) (FMO 5) (Dimethylaniline oxidase 5)
Length = 532
Score = 87.8 bits (216), Expect = 5e-17
Identities = 85/360 (23%), Positives = 151/360 (41%), Gaps = 38/360 (10%)
Query: 44 IVGAGPSGLAVAAYLKQKGVPSLILERSNCIASLWKLKT---------YDRLRLHLPKQV 94
++GAG SGL ++G+ + ERS I LW+ + Y + ++ K++
Sbjct: 7 VIGAGASGLTCIKCCLEEGLEPVCFERSGDIGGLWRFQEAPEEGRASIYQSVVINTSKEM 66
Query: 95 CELPLMEFPSGFPTYPTKQQFIEYLESYSKNFDIRPW--FNETVMHAEFD---ATLGFWR 149
P +P Y Q +EY Y+K FD+ + F TV + +T G W+
Sbjct: 67 MCFSDYPIPDHYPNYMHNSQVLEYFRMYAKEFDLLKYIQFKTTVCSVKKQPDFSTSGQWQ 126
Query: 150 VRSEGKAGMVTEFVCRWLIVATGENAEAVVP--EIEGVDEFVGSIRHTSLYKSGEEFRGK 207
V +E + + V ++V TG + +A +P G+++F G H+ YK+ EF GK
Sbjct: 127 VVTECEGKQQVD-VFDGVLVCTGHHTDAHLPLESFPGIEKFKGKYFHSRDYKNPVEFTGK 185
Query: 208 KVLVVGCGNSGMEVCLDLCNHDAAPSIVVRD-----SPTKRYAGKINFWVVHVVAQVATR 262
+V+V+G GNSG ++ +++ + + R + ++ I+ + + +R
Sbjct: 186 RVIVIGIGNSGGDLAVEISHTAKQVFLSTRRGAWILNRVGKHGYPIDLLLSSRIMYYLSR 245
Query: 263 ATGGSHPSHCVMVNARQHRTVRFGSASVGSP*TQKTVWKDTGPRCGCPCQD*KRRHQGIK 322
G S ++ + Q RF G + + + P R G+
Sbjct: 246 ICGPSLKNNYMEKQMNQ----RFDHEMFGLKPKHRALSQHPTVNDDLP----NRIIAGLV 297
Query: 323 RLKRYTVEFA-------DGSTEN-FDAIILATGYKSNVPYWLKDKGMFSKEDGYPRKPFP 374
++K EF DGS E+ D +I ATGY P+ + + +K FP
Sbjct: 298 KVKGNVKEFTETAAIFEDGSREDGIDVVIFATGYSFAFPFLEDSVKVVKNKVSLYKKVFP 357
>FMO3_MACMU (Q8SPQ7) Dimethylaniline monooxygenase [N-oxide-forming]
3 (EC 1.14.13.8) (Hepatic flavin-containing
monooxygenase 3) (FMO 3) (Dimethylaniline oxidase 3)
Length = 531
Score = 87.4 bits (215), Expect = 6e-17
Identities = 88/331 (26%), Positives = 143/331 (42%), Gaps = 32/331 (9%)
Query: 44 IVGAGPSGLAVAAYLKQKGVPSLILERSNCIASLWKLKT---------YDRLRLHLPKQV 94
I+GAG SGLA ++G+ E+SN I LWK Y + + K++
Sbjct: 6 IIGAGVSGLASIRSCLEEGLEPTCFEKSNDIGGLWKFSDHAEEGRASIYKSVFTNSSKEM 65
Query: 95 CELPLMEFPSGFPTYPTKQQFIEYLESYSKNFDIRPW-----FNETVMHAEFDATLGFWR 149
P +P FP + + EYL +++K + + F +V AT G W
Sbjct: 66 MCFPDFPYPDDFPNFMHNSKIQEYLTAFAKEKSLLKYIQFKTFVSSVNKRPDFATTGQWD 125
Query: 150 VRSEGKAGMVTEFVCRWLIVATGENAEAVVPE--IEGVDEFVGSIRHTSLYKSGEEFRGK 207
V +E + G V ++V +G + +P+ G++ F G H+ YK F+GK
Sbjct: 126 VTTE-RDGKRESAVFDAVMVCSGHHVYPNLPKESFPGLNHFKGKCFHSRDYKEPGVFKGK 184
Query: 208 KVLVVGCGNSGMEVCLDLCNHDAAPSIVVRDSPT---KRYAGKINFWVVHVVAQVAT--- 261
+VLVVG GNSG ++ +L +H A ++ S + R W + ++ + T
Sbjct: 185 RVLVVGLGNSGCDIATEL-SHTAEQVVISSRSGSWVMSRVWDNGYPWDMVLITRFGTFLK 243
Query: 262 --RATGGSHPSHCVMVNARQHRTVRFGSASVGSP*TQKTVWKDTGPRC-GCPCQD*KRRH 318
T S + +NAR + +G + ++ V+ D P C C K
Sbjct: 244 NNLPTAISDWLYMKQMNAR-FKHENYGLMPLNGVLRKEPVFNDELPACILCGIVSVK--- 299
Query: 319 QGIKRLKRYTVEFADGST-ENFDAIILATGY 348
+K+ + F DG+T E D +I ATGY
Sbjct: 300 PNVKKFTETSAIFEDGTTFEGIDCVIFATGY 330
>FMO2_MACMU (Q28505) Dimethylaniline monooxygenase [N-oxide-forming]
2 (EC 1.14.13.8) (Pulmonary flavin-containing
monooxygenase 2) (FMO 2) (Dimethylaniline oxidase 2)
(FMO 1B1)
Length = 534
Score = 85.1 bits (209), Expect = 3e-16
Identities = 86/346 (24%), Positives = 137/346 (38%), Gaps = 50/346 (14%)
Query: 44 IVGAGPSGLAVAAYLKQKGVPSLILERSNCIASLWKLKT---------YDRLRLHLPKQV 94
++GAG SGL +G+ ER+ I +W+ K Y + + K++
Sbjct: 6 VIGAGVSGLISLKCCVDEGLEPTCFERTEDIGGVWRFKEKVEDGRASIYQSVVTNTSKEM 65
Query: 95 CELPLMEFPSGFPTYPTKQQFIEYLESYSKNFDIRPW--FNETVMHA----EFDATLGFW 148
P FP + + +EY ++K FD+ + F TV+ +F ++ G W
Sbjct: 66 SCFSDFPMPEDFPNFLHNSKLLEYFRIFAKKFDLLKYIQFQTTVLSVRKCPDFSSS-GQW 124
Query: 149 RVRSEGKAGMVTEFVCRWLIVATGENAEAVVP--EIEGVDEFVGSIRHTSLYKSGEEFRG 206
+V ++ G V ++V TG + +P G++ F G H+ YK + F G
Sbjct: 125 KVVTQSN-GKEQSAVFDAVMVCTGHHFLPHIPLKSFPGIERFKGQYFHSRQYKHPDGFEG 183
Query: 207 KKVLVVGCGNSGMEVCLDLCNHDAAPSIVVRDSPTKRYAGKINFWVVHVVAQVATRATGG 266
K++LV+G GNSG ++ ++L A I R WV+ V++
Sbjct: 184 KRILVIGMGNSGSDIAVELSKSAAQVFISTRHGT----------WVMSRVSEDGYPWDSV 233
Query: 267 SHPSHCVMVNARQHRTV-----------RFGSASVGSP*TQKTVWK------DTGPRCGC 309
H M+ RTV F + G K + K D R C
Sbjct: 234 FHTRFRSMLRNVLPRTVVKWMIEQQMNQWFNHENYGLEPQNKYIMKEPVLNDDVPSRLLC 293
Query: 310 PCQD*KRRHQGIKRLKRYTVEFADGST-ENFDAIILATGYKSNVPY 354
K +K L + F DG+ EN D II ATGY + P+
Sbjct: 294 GAIKVK---STVKELTETSAIFEDGTVEENIDVIIFATGYSFSFPF 336
>FMO5_HUMAN (P49326) Dimethylaniline monooxygenase [N-oxide-forming]
5 (EC 1.14.13.8) (Hepatic flavin-containing
monooxygenase 5) (FMO 5) (Dimethylaniline oxidase 5)
Length = 532
Score = 84.7 bits (208), Expect = 4e-16
Identities = 91/368 (24%), Positives = 156/368 (41%), Gaps = 54/368 (14%)
Query: 44 IVGAGPSGLAVAAYLKQKGVPSLILERSNCIASLWKLKT---------YDRLRLHLPKQV 94
++G G SGL+ ++G+ + ER++ I LW+ + Y + ++ K++
Sbjct: 7 VIGGGVSGLSSIKCCVEEGLEPVCFERTDDIGGLWRFQENPEEGRASIYKSVIINTSKEM 66
Query: 95 CELPLMEFPSGFPTYPTKQQFIEYLESYSKNFDIRPW--FNETVMHAEFD---ATLGFWR 149
P +P + Q +EY Y+K FD+ + F TV + AT G W
Sbjct: 67 MCFSDYPIPDHYPNFMHNAQVLEYFRMYAKEFDLLKYIRFKTTVCSVKKQPDFATSGQWE 126
Query: 150 V--RSEGKAGMVTEFVCRWLIVATGENAEAVVP--EIEGVDEFVGSIRHTSLYKSGEEFR 205
V SEGK M V ++V TG + A +P G+++F G H+ YK+ E F
Sbjct: 127 VVTESEGKKEMN---VFDGVMVCTGHHTNAHLPLESFPGIEKFKGQYFHSRDYKNPEGFT 183
Query: 206 GKKVLVVGCGNSGMEVCLDLCNHDAAPSIVVRDSPTKRYAGKINFWVVHVVAQVATRA-- 263
GK+V+++G GNSG ++ +++ A + + T+R A W+++ V A
Sbjct: 184 GKRVIIIGIGNSGGDLAVEI--SQTAKQVFL---STRRGA-----WILNRVGDYGYPADV 233
Query: 264 TGGSHPSHCV-------MVNARQHRTV--RFGSASVGSP*TQKTVWKDTGPRCGCPCQD* 314
S +H + + N + + RF G + + + P
Sbjct: 234 LFSSRLTHFIWKICGQSLANKYLEKKINQRFDHEMFGLKPKHRALSQHPTLNDDLP---- 289
Query: 315 KRRHQGIKRLKRYTVEFA-------DGSTE-NFDAIILATGYKSNVPYWLKDKGMFSKED 366
R G+ ++K EF DGS E + DA+I ATGY + P+ + +
Sbjct: 290 NRIISGLVKVKGNVKEFTETAAIFEDGSREDDIDAVIFATGYSFDFPFLEDSVKVVKNKI 349
Query: 367 GYPRKPFP 374
+K FP
Sbjct: 350 SLYKKVFP 357
>FMO4_HUMAN (P31512) Dimethylaniline monooxygenase [N-oxide-forming]
4 (EC 1.14.13.8) (Hepatic flavin-containing
monooxygenase 4) (FMO 4) (Dimethylaniline oxidase 4)
Length = 557
Score = 84.7 bits (208), Expect = 4e-16
Identities = 90/364 (24%), Positives = 152/364 (41%), Gaps = 46/364 (12%)
Query: 44 IVGAGPSGLAVAAYLKQKGVPSLILERSNCIASLWKL---------KTYDRLRLHLPKQV 94
++GAG SGL+ + + ERS+ I LWK + Y L ++ K++
Sbjct: 6 VIGAGVSGLSSIKCCVDEDLEPTCFERSDDIGGLWKFTESSKDGMTRVYKSLVTNVCKEM 65
Query: 95 CELPLMEFPSGFPTYPTKQQFIEYLESYSKNFDIRPW--FNETVM----HAEFDATLGFW 148
F +P + ++F +YL+ ++++FD+ + F TV +F T G W
Sbjct: 66 SCYSDFPFHEDYPNFMNHEKFWDYLQEFAEHFDLLKYIQFKTTVCSITKRPDFSET-GQW 124
Query: 149 RVRSEGKAGMVTEFVCRWLIVATGE--NAEAVVPEIEGVDEFVGSIRHTSLYKSGEEFRG 206
V +E + G V ++V TG N + G+ +F G I H+ YK E F+G
Sbjct: 125 DVVTETE-GKQNRAVFDAVMVCTGHFLNPHLPLEAFPGIHKFKGQILHSQEYKIPEGFQG 183
Query: 207 KKVLVVGCGNSGMEVCLDLCNHDAAPSIVVRDSPTKRYAGKINFWVVHVVAQVATRA--- 263
K+VLV+G GN+G ++ ++L A +++ G+ + W V R
Sbjct: 184 KRVLVIGLGNTGGDIAVELSR--TAAQVLLSTRTGTWVLGRSSDWGYPYNMMVTRRCCSF 241
Query: 264 TGGSHPSHCVMVNARQHRTVRFGSASVGSP*TQ----KTVWKDTGPRCGCPCQD*KRRHQ 319
PS + + RF G T+ K + D P C C
Sbjct: 242 IAQVLPSRFLNWIQERKLNKRFNHEDYGLSITKGKKAKFIVNDELPNC-ILC-------- 292
Query: 320 GIKRLKRYTVEFADGST--------ENFDAIILATGYKSNVPYWLKD-KGMFSKEDGYPR 370
G +K +EF + S EN D +I TGY + P++ + K + +K+ +
Sbjct: 293 GAITMKTSVIEFTETSAVFEDGTVEENIDVVIFTTGYTFSFPFFEEPLKSLCTKKIFLYK 352
Query: 371 KPFP 374
+ FP
Sbjct: 353 QVFP 356
>FMO4_RABIT (P36367) Dimethylaniline monooxygenase [N-oxide-forming]
4 (EC 1.14.13.8) (Hepatic flavin-containing
monooxygenase 4) (FMO 4) (Dimethylaniline oxidase 4)
(FMO 1E1)
Length = 554
Score = 84.3 bits (207), Expect = 5e-16
Identities = 92/353 (26%), Positives = 147/353 (41%), Gaps = 65/353 (18%)
Query: 44 IVGAGPSGLAVAAYLKQKGVPSLILERSNCIASLWKL---------KTYDRLRLHLPKQV 94
++GAG SGL + + ERSN I LWK + Y L ++ K++
Sbjct: 6 VIGAGVSGLTSIKCCLDEDLEPTCFERSNDIGGLWKYTETSKDGMTRIYWSLVTNVCKEM 65
Query: 95 CELPLMEFPSGFPTYPTKQQFIEYLESYSKNFDIRPW--FNETVMHA----EFDATLGFW 148
F +P + + +F YL+ ++++FD+ + F TV +F T G W
Sbjct: 66 SCYSDFPFQEDYPNFMSHSKFWNYLQEFAEHFDLLKYIQFKTTVCSVTKRPDFSKT-GQW 124
Query: 149 RVRSEGKAGMVTEFVCRWLIVATGE--NAEAVVPEIEGVDEFVGSIRHTSLYKSGEEFRG 206
V +E + G V ++V TG+ N + G+ +F G I H YK E FRG
Sbjct: 125 DVVTETE-GKQHRAVFDAVMVCTGKFLNPRLPLESFPGILKFRGQILHCQEYKIPEGFRG 183
Query: 207 KKVLVVGCGNSGMEVCLDLCNHDAAPSIVVRDSPTKRYAGKINFWVVHVVAQVATRATGG 266
++VLV+G GNSG +V ++L A + R WV+ +R++ G
Sbjct: 184 QRVLVIGLGNSGGDVAVELSRVAAQVLLSTRTGT----------WVI-------SRSSNG 226
Query: 267 SHPSHCVM-------------------VNARQHRTVRFGSASVGSP*TQ----KTVWKDT 303
+P + ++ +N RQ RF + G T+ K + D
Sbjct: 227 GYPFNMMITRRCLNVIEQVLPSCFLRWINERQ-MNKRFNHENYGLSITKGKNPKFIVNDE 285
Query: 304 GPRC-GCPCQD*KRRHQGIKRLKRYTVEFADGST-ENFDAIILATGYKSNVPY 354
P C C K +K + F DG+ EN D++I TGY + P+
Sbjct: 286 LPTCILCGTVTVK---TSVKEFTETSAIFEDGTVEENIDSVIFTTGYVFSFPF 335
>Y916_MYCBO (P64746) Probable monooxygenase Mb0916 (EC 1.14.13.-)
Length = 495
Score = 84.0 bits (206), Expect = 7e-16
Identities = 80/340 (23%), Positives = 146/340 (42%), Gaps = 34/340 (10%)
Query: 40 PGPLIVGAGPSGLAVAAYLKQKGVPSL-ILERSNCIASLWKLKTYDRLRLHLPKQVCELP 98
P +VGAG SG+ VA L G+ + I E+++ + W+ TY L +P ++ +
Sbjct: 6 PTVAVVGAGMSGMCVAITLLSAGITDVCIYEKADDVGGTWRDNTYPGLTCDVPSRLYQYS 65
Query: 99 LMEFPSGFPTYPTKQQFIEYLESYSKNFDIRPW--FNETVMHAEFDATLGFWRVRSEGKA 156
+ P+ + + +YL ++ + +R F TV+ A FD G W +R++
Sbjct: 66 FAKNPNWTQMFSRGGEIQDYLRGIAERYGLRHRIRFGATVVSARFDD--GRWVLRTDSG- 122
Query: 157 GMVTEFVCRWLIVATGENAEAVVPEIEGVDEFVGSIRHTSLYKSGEEFRGKKVLVVGCGN 216
TE +LI ATG +P I G+D+F G++ H++ + G+++ V+G G+
Sbjct: 123 ---TESTVDFLISATGVLHHPRIPPIAGLDDFRGTVFHSARWDHTVPLLGRRIAVIGTGS 179
Query: 217 SGMEVCLDLCNHDAAPSIVVRDS------PTKRYA--GKINFWVVHVVAQVATRATGGSH 268
+G+++ L ++ R + P RY+ ++ + +A +A S
Sbjct: 180 TGVQLVCGLAGVAGKVTMFQRTAQWVLPWPNPRYSKLARVFHRAFPCLGSLAYKAYSLSF 239
Query: 269 PSHCV-MVNARQHRTV-----RFGSASVGSP*TQKTVWKDTGPRC-----------GCPC 311
+ V + N HR + R V P ++ + D P C
Sbjct: 240 ETFAVALSNPGLHRKLVGAVCRASLRRVRDPRLRRALTPDYEPMCKRLVMSGGFYRAIQR 299
Query: 312 QD*KRRHQGIKRLKRYTVEFADGSTENFDAIILATGYKSN 351
D + GI ++ + DG D I+LATG+ S+
Sbjct: 300 DDVELVTAGIDHVEHRGIVTDDGVLHEVDVIVLATGFDSH 339
>Y892_MYCTU (P64745) Probable monooxygenase Rv0892/MT0916 (EC
1.14.13.-)
Length = 495
Score = 84.0 bits (206), Expect = 7e-16
Identities = 80/340 (23%), Positives = 146/340 (42%), Gaps = 34/340 (10%)
Query: 40 PGPLIVGAGPSGLAVAAYLKQKGVPSL-ILERSNCIASLWKLKTYDRLRLHLPKQVCELP 98
P +VGAG SG+ VA L G+ + I E+++ + W+ TY L +P ++ +
Sbjct: 6 PTVAVVGAGMSGMCVAITLLSAGITDVCIYEKADDVGGTWRDNTYPGLTCDVPSRLYQYS 65
Query: 99 LMEFPSGFPTYPTKQQFIEYLESYSKNFDIRPW--FNETVMHAEFDATLGFWRVRSEGKA 156
+ P+ + + +YL ++ + +R F TV+ A FD G W +R++
Sbjct: 66 FAKNPNWTQMFSRGGEIQDYLRGIAERYGLRHRIRFGATVVSARFDD--GRWVLRTDSG- 122
Query: 157 GMVTEFVCRWLIVATGENAEAVVPEIEGVDEFVGSIRHTSLYKSGEEFRGKKVLVVGCGN 216
TE +LI ATG +P I G+D+F G++ H++ + G+++ V+G G+
Sbjct: 123 ---TESTVDFLISATGVLHHPRIPPIAGLDDFRGTVFHSARWDHTVPLLGRRIAVIGTGS 179
Query: 217 SGMEVCLDLCNHDAAPSIVVRDS------PTKRYA--GKINFWVVHVVAQVATRATGGSH 268
+G+++ L ++ R + P RY+ ++ + +A +A S
Sbjct: 180 TGVQLVCGLAGVAGKVTMFQRTAQWVLPWPNPRYSKLARVFHRAFPCLGSLAYKAYSLSF 239
Query: 269 PSHCV-MVNARQHRTV-----RFGSASVGSP*TQKTVWKDTGPRC-----------GCPC 311
+ V + N HR + R V P ++ + D P C
Sbjct: 240 ETFAVALSNPGLHRKLVGAVCRASLRRVRDPRLRRALTPDYEPMCKRLVMSGGFYRAIQR 299
Query: 312 QD*KRRHQGIKRLKRYTVEFADGSTENFDAIILATGYKSN 351
D + GI ++ + DG D I+LATG+ S+
Sbjct: 300 DDVELVTAGIDHVEHRGIVTDDGVLHEVDVIVLATGFDSH 339
>FMO6_HUMAN (O60774) Putative dimethylaniline monooxygenase
[N-oxide-forming] 6 (EC 1.14.13.8) (Flavin-containing
monooxygenase 6) (FMO 6) (Dimethylaniline oxidase 6)
Length = 539
Score = 84.0 bits (206), Expect = 7e-16
Identities = 84/338 (24%), Positives = 148/338 (42%), Gaps = 34/338 (10%)
Query: 44 IVGAGPSGLAVAAYLKQKGVPSLILERSNCIASLWKLKT---------YDRLRLHLPKQV 94
I+GAG SGLA ++G+ ERS+ + LWK Y + + K++
Sbjct: 7 IIGAGVSGLAAIWCCLEEGLEPTCFERSDDVGGLWKFSDHTEEGRASIYQSVFTNSSKEM 66
Query: 95 CELPLMEFPSGFPTYPTKQQFIEYLESYSKNFDIRPWFN-ETVMHA-----EFDATLGFW 148
P +P +P Y + EY+++Y++ D+ + ET++ F T G W
Sbjct: 67 MCFPDFPYPDDYPNYIHHSKLQEYIKTYAQKKDLLRYIQFETLVSGIKKCPSFLVT-GQW 125
Query: 149 RVRSEGKAGMVTEFVCRWLIVATGENAEAVVP--EIEGVDEFVGSIRHTSLYKSGEEFRG 206
V +E K G + +++ +G + +P G+D+F G+ H+ YK+ E F+G
Sbjct: 126 VVVTE-KDGKQESTIFDAVMICSGHHVYPNLPTDSFPGLDQFRGNYLHSRDYKNPEAFKG 184
Query: 207 KKVLVVGCGNSGMEVCLDLCNHDAAPSIVVRDSPTKRYAGKI----NFWVVHVVAQVAT- 261
K+VLV+G GNSG ++ ++L A +++ ++ W + V + A+
Sbjct: 185 KRVLVIGLGNSGSDIAVELSR--LATQVIISTRSASWVMSRVWDDGYPWDMMYVTRFASF 242
Query: 262 -RATGGSHPSHCVMVNARQ--HRTVRFGSASVGSP*TQKTVWKDTGP-RCGCPCQD*KRR 317
R S S + V + +G + ++ V+ D P R C K
Sbjct: 243 LRNVLPSFISDWLYVQKMNTWFKHENYGLMPLNGSLRKEPVFNDELPSRILCGTLSIK-- 300
Query: 318 HQGIKRLKRYTVEFADGST-ENFDAIILATGYKSNVPY 354
+K + F DG+ E D++I ATGY + P+
Sbjct: 301 -PSVKEFTETSAVFEDGTMFEAIDSVIFATGYDYSYPF 337
>FMO2_PANTR (Q8HZ70) Dimethylaniline monooxygenase [N-oxide-forming]
2 (EC 1.14.13.8) (Pulmonary flavin-containing
monooxygenase 2) (FMO 2) (Dimethylaniline oxidase 2)
(FMO 1B1)
Length = 534
Score = 84.0 bits (206), Expect = 7e-16
Identities = 83/346 (23%), Positives = 136/346 (38%), Gaps = 50/346 (14%)
Query: 44 IVGAGPSGLAVAAYLKQKGVPSLILERSNCIASLWKLKT---------YDRLRLHLPKQV 94
++GAG SGL +G+ ER+ I +W+ K Y + + K++
Sbjct: 6 VIGAGVSGLISLKCCVDEGLEPTCFERTEDIGGVWRFKENVEDGRASIYQSVITNTSKEM 65
Query: 95 CELPLMEFPSGFPTYPTKQQFIEYLESYSKNFDIRPW--FNETVMHA----EFDATLGFW 148
P FP + + +EY ++K FD+ + F TV+ +F ++ G W
Sbjct: 66 SCFSDFPMPEDFPNFLHNSKLLEYFRIFAKKFDLLKYIQFQTTVLSVRKCPDFSSS-GQW 124
Query: 149 RVRSEGKAGMVTEFVCRWLIVATGENAEAVVP--EIEGVDEFVGSIRHTSLYKSGEEFRG 206
+V ++ G V ++V +G + +P G++ F G H+ YK + F G
Sbjct: 125 KVVTQSN-GKEQSAVFDAVMVCSGHHILPHIPLKSFPGIERFKGQYFHSRQYKHPDGFEG 183
Query: 207 KKVLVVGCGNSGMEVCLDLCNHDAAPSIVVRDSPTKRYAGKINFWVVHVVAQVATRATGG 266
K++LV+G GNSG ++ ++L + A I R WV+ +++
Sbjct: 184 KRILVIGMGNSGSDIAVELSKNAAQVFISTRHGT----------WVMSRISEDGYPWDSV 233
Query: 267 SH-----------PSHCVMVNARQHRTVRFGSASVGSP*TQKTVWK------DTGPRCGC 309
H P V Q F + G K + K D R C
Sbjct: 234 FHTRFRSMLRNVLPRTAVKWMIEQQMNRWFNHENYGLEPQNKYIMKEPVLNDDVPSRLLC 293
Query: 310 PCQD*KRRHQGIKRLKRYTVEFADGST-ENFDAIILATGYKSNVPY 354
K +K L + F DG+ EN D II ATGY + P+
Sbjct: 294 GAIKVK---STVKELTETSAIFEDGTVEENIDVIIFATGYSFSFPF 336
>FMO2_GORGO (Q8HZ69) Dimethylaniline monooxygenase [N-oxide-forming]
2 (EC 1.14.13.8) (Pulmonary flavin-containing
monooxygenase 2) (FMO 2) (Dimethylaniline oxidase 2)
(FMO 1B1)
Length = 534
Score = 84.0 bits (206), Expect = 7e-16
Identities = 83/346 (23%), Positives = 136/346 (38%), Gaps = 50/346 (14%)
Query: 44 IVGAGPSGLAVAAYLKQKGVPSLILERSNCIASLWKLKT---------YDRLRLHLPKQV 94
++GAG SGL +G+ ER+ I +W+ K Y + + K++
Sbjct: 6 VIGAGVSGLISLKCCVDEGLEPTCFERTEDIGGVWRFKENVEDGRASIYQSVVTNTSKEM 65
Query: 95 CELPLMEFPSGFPTYPTKQQFIEYLESYSKNFDIRPW--FNETVMHA----EFDATLGFW 148
P FP + + +EY ++K FD+ + F TV+ +F ++ G W
Sbjct: 66 SCFSDFPMPEDFPNFLHNSKLLEYFRIFAKKFDLLKYIQFQTTVLSVRKCPDFSSS-GQW 124
Query: 149 RVRSEGKAGMVTEFVCRWLIVATGENAEAVVP--EIEGVDEFVGSIRHTSLYKSGEEFRG 206
+V ++ G V ++V +G + +P G++ F G H+ YK + F G
Sbjct: 125 KVVTQSN-GKEQNAVFDAVMVCSGHHILPHIPLKSFPGIERFKGQYFHSRQYKHPDGFEG 183
Query: 207 KKVLVVGCGNSGMEVCLDLCNHDAAPSIVVRDSPTKRYAGKINFWVVHVVAQVATRATGG 266
K++LV+G GNSG ++ ++L + A I R WV+ +++
Sbjct: 184 KRILVIGMGNSGSDIAVELSKNAAQVFISTRHGT----------WVMSRISEDGYPWDAV 233
Query: 267 SH-----------PSHCVMVNARQHRTVRFGSASVGSP*TQKTVWK------DTGPRCGC 309
H P V Q F + G K + K D R C
Sbjct: 234 FHTRFRSMLRNVLPRTAVKWMIEQQMNRWFNHENYGLEPQNKYIMKEPVLNDDVPSRLLC 293
Query: 310 PCQD*KRRHQGIKRLKRYTVEFADGST-ENFDAIILATGYKSNVPY 354
K +K L + F DG+ EN D II ATGY + P+
Sbjct: 294 GAIKVK---STVKELTETSAIFEDGTVEENIDVIIFATGYSFSFPF 336
>FMO2_HUMAN (Q99518) Dimethylaniline monooxygenase [N-oxide-forming]
2 (EC 1.14.13.8) (Pulmonary flavin-containing
monooxygenase 2) (FMO 2) (Dimethylaniline oxidase 2)
(FMO 1B1)
Length = 534
Score = 83.2 bits (204), Expect = 1e-15
Identities = 83/346 (23%), Positives = 136/346 (38%), Gaps = 50/346 (14%)
Query: 44 IVGAGPSGLAVAAYLKQKGVPSLILERSNCIASLWKLKT---------YDRLRLHLPKQV 94
++GAG SGL +G+ ER+ I +W+ K Y + + K++
Sbjct: 6 VIGAGVSGLISLKCCVDEGLEPTCFERTEDIGGVWRFKENVEDGRASIYQSVVTNTSKEM 65
Query: 95 CELPLMEFPSGFPTYPTKQQFIEYLESYSKNFDIRPW--FNETVMHA----EFDATLGFW 148
P FP + + +EY ++K FD+ + F TV+ +F ++ G W
Sbjct: 66 SCFSDFPMPEDFPNFLHNSKLLEYFRIFAKKFDLLKYIQFQTTVLSVRKCPDFSSS-GQW 124
Query: 149 RVRSEGKAGMVTEFVCRWLIVATGENAEAVVP--EIEGVDEFVGSIRHTSLYKSGEEFRG 206
+V ++ G V ++V +G + +P G++ F G H+ YK + F G
Sbjct: 125 KVVTQSN-GKEQSAVFDAVMVCSGHHILPHIPLKSFPGMERFKGQYFHSRQYKHPDGFEG 183
Query: 207 KKVLVVGCGNSGMEVCLDLCNHDAAPSIVVRDSPTKRYAGKINFWVVHVVAQVATRATGG 266
K++LV+G GNSG ++ ++L + A I R WV+ +++
Sbjct: 184 KRILVIGMGNSGSDIAVELSKNAAQVFISTRHGT----------WVMSRISEDGYPWDSV 233
Query: 267 SH-----------PSHCVMVNARQHRTVRFGSASVGSP*TQKTVWK------DTGPRCGC 309
H P V Q F + G K + K D R C
Sbjct: 234 FHTRFRSMLRNVLPRTAVKWMIEQQMNRWFNHENYGLEPQNKYIMKEPVLNDDVPSRLLC 293
Query: 310 PCQD*KRRHQGIKRLKRYTVEFADGST-ENFDAIILATGYKSNVPY 354
K +K L + F DG+ EN D II ATGY + P+
Sbjct: 294 GAIKVK---STVKELTETSAIFEDGTVEENIDVIIFATGYSFSFPF 336
>FMO3_HUMAN (P31513) Dimethylaniline monooxygenase [N-oxide-forming]
3 (EC 1.14.13.8) (Hepatic flavin-containing
monooxygenase 3) (FMO 3) (Dimethylaniline oxidase 3)
(FMO form 2) (FMO II)
Length = 531
Score = 82.8 bits (203), Expect = 2e-15
Identities = 87/339 (25%), Positives = 139/339 (40%), Gaps = 36/339 (10%)
Query: 44 IVGAGPSGLAVAAYLKQKGVPSLILERSNCIASLWKLKT---------YDRLRLHLPKQV 94
I+GAG SGLA ++G+ E+SN I LWK Y + + K++
Sbjct: 6 IIGAGVSGLASIRSCLEEGLEPTCFEKSNDIGGLWKFSDHAEEGRASIYKSVFSNSSKEM 65
Query: 95 CELPLMEFPSGFPTYPTKQQFIEYLESYSKNFDI------RPWFNETVMHAEFDATLGFW 148
P FP FP + + EY+ +++K ++ + + + H +F AT G W
Sbjct: 66 MCFPDFPFPDDFPNFMHNSKIQEYIIAFAKEKNLLKYIQFKTFVSSVNKHPDF-ATTGQW 124
Query: 149 RVRSEGKAGMVTEFVCRWLIVATGENAEAVVPE--IEGVDEFVGSIRHTSLYKSGEEFRG 206
V +E + G V ++V +G + +P+ G++ F G H+ YK F G
Sbjct: 125 DVTTE-RDGKKESAVFDAVMVCSGHHVYPNLPKESFPGLNHFKGKCFHSRDYKEPGVFNG 183
Query: 207 KKVLVVGCGNSGMEVCLDLCNHDAAPSIVVRDSP--TKRYAGKINFWVVHVVAQVAT--- 261
K+VLVVG GNSG ++ +L I R R W + +V + T
Sbjct: 184 KRVLVVGLGNSGCDIATELSRTAEQVMISSRSGSWVMSRVWDNGYPWDMLLVTRFGTFLK 243
Query: 262 --RATGGSHPSHCVMVNARQHRTVRFGSASVGSP*TQKTVWKDTGPR---CGCPCQD*KR 316
T S + +NAR + +G + ++ V+ D P CG
Sbjct: 244 NNLPTAISDWLYVKQMNAR-FKHENYGLMPLNGVLRKEPVFNDELPASILCGIVSV---- 298
Query: 317 RHQGIKRLKRYTVEFADGST-ENFDAIILATGYKSNVPY 354
+K + F DG+ E D +I ATGY P+
Sbjct: 299 -KPNVKEFTETSAIFEDGTIFEGIDCVIFATGYSFAYPF 336
>FMO3_PANTR (Q7YS44) Dimethylaniline monooxygenase [N-oxide-forming]
3 (EC 1.14.13.8) (Hepatic flavin-containing
monooxygenase 3) (FMO 3) (Dimethylaniline oxidase 3)
Length = 531
Score = 81.3 bits (199), Expect = 4e-15
Identities = 87/338 (25%), Positives = 137/338 (39%), Gaps = 34/338 (10%)
Query: 44 IVGAGPSGLAVAAYLKQKGVPSLILERSNCIASLWKLKT---------YDRLRLHLPKQV 94
I+GAG SGLA ++G+ E+SN I LWK Y + + K++
Sbjct: 6 IIGAGVSGLASIRSCLEEGLEPTCFEKSNDIGGLWKFSDHAEEGRASIYKSVFSNSSKEM 65
Query: 95 CELPLMEFPSGFPTYPTKQQFIEYLESYSKNFDIRPW-----FNETVMHAEFDATLGFWR 149
P FP FP + + EY+ +++K ++ + F +V AT G W
Sbjct: 66 MCFPDFPFPDDFPNFMHNSKIQEYIIAFAKEKNLLKYIQFKTFVSSVNKRPDFATTGQWD 125
Query: 150 VRSEGKAGMVTEFVCRWLIVATGENAEAVVPE--IEGVDEFVGSIRHTSLYKSGEEFRGK 207
V +E + G V ++V +G + +P+ G++ F G H+ YK F GK
Sbjct: 126 VTTE-RDGKKESAVFDAVMVCSGHHVYPNLPKESFPGLNHFKGKCFHSRDYKEPGVFNGK 184
Query: 208 KVLVVGCGNSGMEVCLDLCNHDAAPSIVVRDSP--TKRYAGKINFWVVHVVAQVAT---- 261
+VLVVG GNSG ++ +L I R R W + +V + T
Sbjct: 185 RVLVVGLGNSGCDIATELSRTAEQVMISSRSGSWVMSRVWDNGYPWDMLLVTRFGTFLKN 244
Query: 262 -RATGGSHPSHCVMVNARQHRTVRFGSASVGSP*TQKTVWKDTGPR---CGCPCQD*KRR 317
T S + +NAR + +G + ++ V+ D P CG
Sbjct: 245 NLPTAISDWLYVKQMNAR-FKHENYGLMPLNGVLRKEPVFNDELPASILCGIVSV----- 298
Query: 318 HQGIKRLKRYTVEFADGST-ENFDAIILATGYKSNVPY 354
+K + F DG+ E D +I ATGY P+
Sbjct: 299 KPNVKEFTETSAIFEDGTIFEGIDCVIFATGYSFAYPF 336
>FMO5_CAVPO (P49109) Dimethylaniline monooxygenase [N-oxide-forming]
5 (EC 1.14.13.8) (Hepatic flavin-containing
monooxygenase 5) (FMO 5) (Dimethylaniline oxidase 5)
Length = 532
Score = 79.7 bits (195), Expect = 1e-14
Identities = 85/373 (22%), Positives = 151/373 (39%), Gaps = 64/373 (17%)
Query: 44 IVGAGPSGLAVAAYLKQKGVPSLILERSNCIASLWKLKT---------YDRLRLHLPKQV 94
++G G SGL+ ++G+ + ERS I LW+ + Y + ++ K++
Sbjct: 7 VIGGGVSGLSSIKCCLEEGLEPVCFERSADIGGLWRFQENPEEGRASIYKSVIINTSKEM 66
Query: 95 CELPLMEFPSGFPTYPTKQQFIEYLESYSKNFDIRPW--FNETVMHAEFD---ATLGFWR 149
P +P + +EY Y+K F + + F TV + + +T G W
Sbjct: 67 MCFSDYPIPDHYPNFMHNSHVLEYFRMYAKEFGLLKYIQFKTTVCNVKKRPDFSTSGQWE 126
Query: 150 VRSEGKAGMVTEFVCRWLIVATGENAEAVVP--EIEGVDEFVGSIRHTSLYKSGEEFRGK 207
V +E + G V ++V TG + A +P G+++F G H+ YK+ E F GK
Sbjct: 127 VVTEHE-GKTKVDVFDAVMVCTGHHTNAHLPLESFPGIEKFKGQYFHSRDYKNPEAFTGK 185
Query: 208 KVLVVGCGNSGMEVCLDLCNHDAAPSIVVRDSPTKRYAGKINFWVVHVVAQVATRATGGS 267
+V+++G GNSG ++ +++ +H A + T+R W+++ V +
Sbjct: 186 RVVIIGIGNSGGDLAVEI-SHTAKQVFL----STRR-----GSWILNRVGK-------HG 228
Query: 268 HPSHCVMVNARQHRTVRFGSASVGSP*TQKTVWKDTGPRCGCPCQD*KRRHQ-------- 319
+P+ ++ R F S +G + V K R K +H+
Sbjct: 229 YPTDVLL----SSRFTYFLSKILGQSLSNAYVEKQMNERFDHEMFGLKPKHRAMSQHPTV 284
Query: 320 -----------------GIKRLKRYTVEFADGSTE-NFDAIILATGYKSNVPYWLKDKGM 361
+K F DGS E + DA+I ATGY + P+ +
Sbjct: 285 NDDLPNRIIAGMVKVKGNVKEFTETAAIFEDGSREDDIDAVIFATGYSFDFPFLEDSVKV 344
Query: 362 FSKEDGYPRKPFP 374
+ +K FP
Sbjct: 345 VKNKVSLYKKVFP 357
>FMO1_HUMAN (Q01740) Dimethylaniline monooxygenase [N-oxide-forming]
1 (EC 1.14.13.8) (Fetal hepatic flavin-containing
monooxygenase 1) (FMO 1) (Dimethylaniline oxidase 1)
Length = 531
Score = 78.6 bits (192), Expect = 3e-14
Identities = 59/200 (29%), Positives = 90/200 (44%), Gaps = 23/200 (11%)
Query: 44 IVGAGPSGLAVAAYLKQKGVPSLILERSNCIASLWKLKTY-DRLRLHLPKQVCELPLME- 101
IVGAG SGLA ++G+ ERS+ + LW+ + + R L K V E
Sbjct: 6 IVGAGVSGLASIKCCLEEGLEPTCFERSDDLGGLWRFTEHVEEGRASLYKSVVSNSCKEM 65
Query: 102 -------FPSGFPTYPTKQQFIEYLESYSKNFDIRPWFNE-----TVMHAEFDATLGFWR 149
FP +P Y QF+EYL+ Y+ +FD+ +V A G W
Sbjct: 66 SCYSDFPFPEDYPNYVPNSQFLEYLKMYANHFDLLKHIQFKTKVCSVTKCSDSAVSGQWE 125
Query: 150 V---RSEGKAGMVTEFVCRWLIVATGENAEAVVP--EIEGVDEFVGSIRHTSLYKSGEEF 204
V E + + + V +V TG +P G++ F G H+ YK + F
Sbjct: 126 VVTMHEEKQESAIFDAV----MVCTGFLTNPYLPLDSFPGINAFKGQYFHSRQYKHPDIF 181
Query: 205 RGKKVLVVGCGNSGMEVCLD 224
+ K+VLV+G GNSG ++ ++
Sbjct: 182 KDKRVLVIGMGNSGTDIAVE 201
>FMO1_PIG (P16549) Dimethylaniline monooxygenase [N-oxide-forming] 1
(EC 1.14.13.8) (Hepatic flavin-containing monooxygenase
1) (FMO 1) (Dimethylaniline oxidase 1)
Length = 531
Score = 77.8 bits (190), Expect = 5e-14
Identities = 61/200 (30%), Positives = 89/200 (44%), Gaps = 23/200 (11%)
Query: 44 IVGAGPSGLAVAAYLKQKGVPSLILERSNCIASLWKLKTY-DRLRLHLPKQVCE------ 96
IVGAG SGLA ++G+ ERS+ + LW+ + + R L K V
Sbjct: 6 IVGAGVSGLASIKCCLEEGLEPTCFERSDDLGGLWRFTEHVEEGRASLYKSVVSNSCKEM 65
Query: 97 --LPLMEFPSGFPTYPTKQQFIEYLESYSKNFDIRPWFN------ETVMHAEFDATLGFW 148
P FP +P Y F+EYL Y+ F++ H +F+ T G W
Sbjct: 66 SCYPDFPFPEDYPNYVPNSHFLEYLRMYANQFNLLKCIQFKTKVCSVTKHEDFNTT-GQW 124
Query: 149 RVRS--EGKAGMVTEFVCRWLIVATGENAEAVVP--EIEGVDEFVGSIRHTSLYKSGEEF 204
V + EGK V ++V TG +P G++ F G H+ YK + F
Sbjct: 125 DVVTLCEGKQESA---VFDAVMVCTGFLTNPYLPLDSFPGINTFKGQYFHSRQYKHPDIF 181
Query: 205 RGKKVLVVGCGNSGMEVCLD 224
+ K VLVVG GNSG ++ ++
Sbjct: 182 KDKSVLVVGMGNSGTDIAVE 201
>FMO3_MOUSE (P97501) Dimethylaniline monooxygenase [N-oxide-forming]
3 (EC 1.14.13.8) (Hepatic flavin-containing
monooxygenase 3) (FMO 3) (Dimethylaniline oxidase 3)
Length = 534
Score = 77.0 bits (188), Expect = 8e-14
Identities = 83/336 (24%), Positives = 139/336 (40%), Gaps = 30/336 (8%)
Query: 44 IVGAGPSGLAVAAYLKQKGVPSLILERSNCIASLWKLKT---------YDRLRLHLPKQV 94
I+GAG SGLA ++G+ ERS+ + LWK Y + + K++
Sbjct: 7 IIGAGVSGLAAIRSCLEEGLEPTCFERSDDVGGLWKFSDHIEEGRASIYQSVFTNSSKEM 66
Query: 95 CELPLMEFPSGFPTYPTKQQFIEYLESYSKNFDIRPWFN-----ETVMHAEFDATLGFWR 149
P +P FP + + EY+ S++K ++ + ++ +T G W
Sbjct: 67 MCFPDFPYPDDFPNFMHHSKLQEYITSFAKEKNLLKYIQFETPVTSINKCPNFSTTGKWE 126
Query: 150 VRSEGKAGMVTEFVCRWLIVATGENAEAVVPE--IEGVDEFVGSIRHTSLYKSGEEFRGK 207
V +E K G V ++ +G + VP+ G++ F G H+ YK ++GK
Sbjct: 127 VTTE-KHGKKETAVFDATMICSGHHIFPHVPKDSFPGLNRFKGKCFHSRDYKEPGIWKGK 185
Query: 208 KVLVVGCGNSGMEVCLDLCNHDAAPSIVVRDSP--TKRYAGKINFWVVHVVAQVAT---- 261
+VLV+G GNSG ++ +L + +I R R W + V+ + T
Sbjct: 186 RVLVIGLGNSGCDIAAELSHVAQKVTISSRSGSWVMSRVWDDGYPWDMVVLTRFQTFLKN 245
Query: 262 -RATGGSHPSHCVMVNARQHRTVRFGSASVGSP*TQKTVWKDTGP-RCGCPCQD*KRRHQ 319
T S + +NAR + +G + ++ V+ D P R C K
Sbjct: 246 NLPTAISDWWYTRQMNAR-FKHENYGLVPLNRTLRKEPVFNDELPARILCGMVTIK---P 301
Query: 320 GIKRLKRYTVEFADGST-ENFDAIILATGYKSNVPY 354
+K + F DG+ E D +I ATGY P+
Sbjct: 302 NVKEFTETSAVFEDGTMFEAIDCVIFATGYGYAYPF 337
>FMO2_CAVPO (P36366) Dimethylaniline monooxygenase [N-oxide-forming]
2 (EC 1.14.13.8) (Pulmonary flavin-containing
monooxygenase 2) (FMO 2) (Dimethylaniline oxidase 2)
(FMO 1B1)
Length = 534
Score = 75.9 bits (185), Expect = 2e-13
Identities = 79/343 (23%), Positives = 136/343 (39%), Gaps = 44/343 (12%)
Query: 44 IVGAGPSGLAVAAYLKQKGVPSLILERSNCIASLWKLKT---------YDRLRLHLPKQV 94
++GAG SGL +G+ ER+ I LW+ K Y + + K++
Sbjct: 6 VIGAGVSGLISLKCCVDEGLEPTCFERTEDIGGLWRFKENVEDGRASIYKSVITNTSKEM 65
Query: 95 CELPLMEFPSGFPTYPTKQQFIEYLESYSKNFDIRPW--FNETVM----HAEFDATLGFW 148
P FP + + +EY ++K FD+ + F TV+ H +F ++ G W
Sbjct: 66 SCFSDFPMPEDFPNFLHNSKLLEYFRLFAKKFDLLKYIQFQTTVLTVKKHPDFSSS-GQW 124
Query: 149 RVRSEGKAGMVTEFVCRWLIVATGENAEAVVP--EIEGVDEFVGSIRHTSLYKSGEEFRG 206
V ++ G V ++V +G + +P G++ F G H+ YK F G
Sbjct: 125 EVVTQSD-GKEQSAVFDAVMVCSGHHILPHIPLKSFPGIERFKGQYFHSRQYKHPAGFEG 183
Query: 207 KKVLVVGCGNSGMEVCLDLCNHDAAPSIVVRDSPTKRYAGKINFWVVHVVAQVATRATGG 266
K++LV+G GNS ++ +L + A I R+ WV+ +++
Sbjct: 184 KRILVIGIGNSASDIASELSKNAAQVFISTRNGS----------WVMSRISEDGYPWDMV 233
Query: 267 SHPSHCVMVNARQHRTVR-----------FGSASVGSP*TQKTVWKDTGPRCGCPCQ--- 312
H M+ RTV F A+ K + K+ P +
Sbjct: 234 FHTRFKSMLRNILPRTVSKWMMEQQLNRWFNHANYSLEPKNKYLMKEPILNDDLPSRILY 293
Query: 313 D*KRRHQGIKRLKRYTVEFADGST-ENFDAIILATGYKSNVPY 354
+ + +L + F DG+ E+ D I+ ATGY + P+
Sbjct: 294 GAVKVKSRVTQLTETSALFEDGTVEEDIDVIVFATGYTFSFPF 336
Database: sprot
Posted date: Nov 25, 2004 10:54 AM
Number of letters in database: 59,974,054
Number of sequences in database: 164,201
Lambda K H
0.322 0.138 0.442
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 54,035,196
Number of Sequences: 164201
Number of extensions: 2404154
Number of successful extensions: 6156
Number of sequences better than 10.0: 116
Number of HSP's better than 10.0 without gapping: 70
Number of HSP's successfully gapped in prelim test: 46
Number of HSP's that attempted gapping in prelim test: 5933
Number of HSP's gapped (non-prelim): 197
length of query: 423
length of database: 59,974,054
effective HSP length: 113
effective length of query: 310
effective length of database: 41,419,341
effective search space: 12839995710
effective search space used: 12839995710
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 67 (30.4 bits)
Medicago: description of AC127429.3