BLAST2 result
BLASTP 2.2.2 [Dec-14-2001]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= AC127021.9 + phase: 0
(540 letters)
Database: sprot
164,201 sequences; 59,974,054 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
C941_VICSA (O81117) Cytochrome P450 94A1 (EC 1.14.-.-) (P450-dep... 383 e-106
C942_VICSA (P98188) Cytochrome P450 94A2 (EC 1.14.-.-) (P450-dep... 367 e-101
C862_ARATH (O23066) Cytochrome P450 86A2 (EC 1.14.-.-) 310 8e-84
C861_ARATH (P48422) Cytochrome P450 86A1 (EC 1.14.-.-) (CYPLXXXV... 287 4e-77
CP5D_CANMA (P16141) Cytochrome P450 52A4 (EC 1.14.14.-) (CYPLIIA... 165 3e-40
CP5A_CANTR (P10615) Cytochrome P450 52A1 (EC 1.14.14.-) (CYPLIIA... 160 8e-39
CP5E_CANMA (P24458) Cytochrome P450 52A5 (EC 1.14.14.-) (CYPLIIA... 160 1e-38
CP5B_CANTR (P30607) Cytochrome P450 52A2 (EC 1.14.14.-) (CYPLIIA... 159 2e-38
CP5J_CANMA (Q12588) Cytochrome P450 52A10 (EC 1.14.14.-) (CYPLII... 155 3e-37
CP5M_DEBHA (Q9Y758) Cytochrome P450 52A13 (EC 1.14.14.-) (Alkane... 154 7e-37
CP5K_CANMA (Q12589) Cytochrome P450 52A11 (EC 1.14.14.-) (CYPLII... 153 1e-36
CP5C_CANMA (P16496) Cytochrome P450 52A3 (EC 1.14.14.-) (CYPLIIA... 151 5e-36
CP5F_CANTR (P30608) Cytochrome P450 52A6 (EC 1.14.14.-) (CYPLIIA... 149 2e-35
CP5T_CANMA (Q12585) Cytochrome P450 52D1 (EC 1.14.14.-) (CYPLIID... 148 4e-35
CP5L_DEBHA (Q9Y757) Cytochrome P450 52A12 (EC 1.14.14.-) (Alkane... 143 1e-33
CP46_MOUSE (Q9WVK8) Cytochrome p450 46A1 (EC 1.14.-.-) (Choleste... 142 3e-33
CP46_HUMAN (Q9Y6A2) Cytochrome p450 46A1 (EC 1.14.-.-) (Choleste... 139 2e-32
CP5W_CANAP (Q12573) Cytochrome P450 52E2 (EC 1.14.14.-) (CYPLIIE2) 134 6e-31
CP5I_CANMA (Q12586) Cytochrome P450 52A9 (EC 1.14.14.-) (CYPLIIA... 133 1e-30
CP5V_CANAP (P43083) Cytochrome P450 52E1 (EC 1.14.14.-) (CYPLIIE1) 132 3e-30
>C941_VICSA (O81117) Cytochrome P450 94A1 (EC 1.14.-.-)
(P450-dependent fatty acid omega-hydroxylase)
Length = 514
Score = 383 bits (983), Expect = e-106
Identities = 209/471 (44%), Positives = 303/471 (63%), Gaps = 28/471 (5%)
Query: 81 MSWSNKFVNLVDYYTHLLQESPTGTIHVH-VLGNT--ITSNPENVEYILKTNFNNYPKGK 137
+S+ + + + ++Q SP+ T + LG IT NP V++ILK F+NY KG
Sbjct: 58 LSFRKNLHRRIQWLSDIVQISPSATFQLDGTLGKRQIITGNPSTVQHILKNQFSNYQKGT 117
Query: 138 QFSTILGDLLGRGIFNVDGHSWKFQRKMASLELGSVVIRSYAMELVIEEIKTRLLPLIAS 197
F+ L D LG GIFN +G +WKFQR++AS E + IR++ +V E+ RL+P++ S
Sbjct: 118 TFTNTLSDFLGTGIFNTNGPNWKFQRQVASHEFNTKSIRNFVEHIVDTELTNRLIPILTS 177
Query: 198 VAEKKTASKADNTSEDVLLDMQDILRRFSFDNICKFSFGLDPCCLVPSLPVSNLANAFDL 257
+T + +LD QDIL+RF+FDNIC +FG DP L PS S A A++
Sbjct: 178 -----------STQTNNILDFQDILQRFTFDNICNIAFGYDPEYLTPSTNRSKFAEAYED 226
Query: 258 SSTLSAQRALTASPLIWKMKRFFNIGSEKKLKEAIKIVNDLANEMIKQR-REIENGVE-S 315
++ +S++R P+IWK+K++FNIGSEK+LKEA+ V A ++++++ RE+E
Sbjct: 227 ATEISSKRFRLPLPIIWKIKKYFNIGSEKRLKEAVTEVRSFAKKLVREKKRELEEKSSLE 286
Query: 316 RKDLLSRFMGALNSHDDEYLRDIVVSFLLAGRDTVASALTGFFILLSKNPKVEEKIRVEL 375
+D+LSRF+ + +S D++++ DIV+SF+LAG+DT ++ALT FF LL KNP+VEE+I EL
Sbjct: 287 TEDMLSRFLSSGHS-DEDFVADIVISFILAGKDTTSAALTWFFWLLWKNPRVEEEIVNEL 345
Query: 376 DRVMNPNQECATFEQTREMHYLNGAIHESMRLFPPVQFDSKFALEDDVLPDGTFIKKGSR 435
+ E +++ +EM Y + A+ ESMRL+PPV DSK A+ DDVLPDG +KKG+
Sbjct: 346 SK----KSELMVYDEVKEMVYTHAALSESMRLYPPVPMDSKEAVNDDVLPDGWVVKKGTI 401
Query: 436 VTYHPYAMGRMENIWGPDCLEFKPERWLKDG------VFVPKCPFKYPVFQAGSRVCLGK 489
VTYH YAMGRM+++WG D EF+PERWL+ VFV + + YPVFQAG RVCLGK
Sbjct: 402 VTYHVYAMGRMKSLWGDDWAEFRPERWLEKDEVNGKWVFVGRDSYSYPVFQAGPRVCLGK 461
Query: 490 ELAIVEMKSVVASLVKRFD-VRVVGPNQEPQFAPGLTASFRGGLPVKIYER 539
E+A ++MK +VA +V +F V QEP F L++ GG PV I +R
Sbjct: 462 EMAFMQMKRIVAGIVGKFKVVPEAHLAQEPGFISFLSSQMEGGFPVTIQKR 512
>C942_VICSA (P98188) Cytochrome P450 94A2 (EC 1.14.-.-)
(P450-dependent fatty acid omega-hydroxylase)
Length = 513
Score = 367 bits (943), Expect = e-101
Identities = 220/526 (41%), Positives = 315/526 (59%), Gaps = 42/526 (7%)
Query: 39 MSTTFTFLFFSFTLLFSFFSFLLFISRIKP-WCNCNTCKTFLTMSWS---------NKFV 88
+ T ++L FS +L + F FL ++ KP +T T + S+ F
Sbjct: 3 LETLISWLLFSTSLFW--FLFLATKTKSKPPKTPSSTTNTPIPKSYPIFGSAFSLLANFH 60
Query: 89 NLVDYYTHLLQESPTGTIHVHV---LGNTITSNPENVEYILKTNFNNYPKGKQFSTILGD 145
+ + + +LQ P+ T +H T+ P V++IL+TNF Y KG F + D
Sbjct: 61 RRIQWTSDILQTIPSSTFVLHRPFGARQVFTAQPAVVQHILRTNFTCYGKGLTFYQSIND 120
Query: 146 LLGRGIFNVDGHSWKFQRKMASLELGSVVIRSYAMELVIEEIKTRLLPLIASVAEKKTAS 205
LG GIFN DG SWKFQR+++S E + +R + +V E+ RL+P+++ + +T
Sbjct: 121 FLGDGIFNADGESWKFQRQISSHEFNTRSLRKFVETVVDVELSDRLVPVLSQASNSQTT- 179
Query: 206 KADNTSEDVLLDMQDILRRFSFDNICKFSFGLDPCCLVPSLPVSNLANAFDLSSTLSAQR 265
LD QDIL+R +FDNIC +FG DP L+PSLP A AFD SS LS +R
Sbjct: 180 ----------LDFQDILQRLTFDNICMIAFGYDPEYLLPSLPEIPFAKAFDESSQLSIER 229
Query: 266 ALTASPLIWKMKRFFNIGSEKKLKEAIKIVNDLANEMIKQRREI--ENGVESRK---DLL 320
PL+WK+KRF NIG E++LKEA+ V LA +++K +++ E ++S DLL
Sbjct: 230 LNALIPLLWKVKRFLNIGVERQLKEAVAEVRGLATKIVKNKKKELKEKALQSESESVDLL 289
Query: 321 SRFMGALNSHDDEYLRDIVVSFLLAGRDTVASALTGFFILLSKNPKVEEKIRVELDRVMN 380
SRF+ + +S D+ ++ D+V+S +LAGRDT ++ALT FF LLSK+ VE +I E+
Sbjct: 290 SRFLSSGHS-DESFVTDMVISIILAGRDTTSAALTWFFWLLSKHSHVENEILKEI----T 344
Query: 381 PNQECATFEQTREMHYLNGAIHESMRLFPPVQFDSKFALEDDVLPDGTFIKKGSRVTYHP 440
E +++ ++M Y + A+ ESMRL+PP+ D+K A+ DDVLPDGT +KKG RVTYH
Sbjct: 345 GKSETVGYDEVKDMVYTHAALCESMRLYPPLPVDTKVAVHDDVLPDGTLVKKGWRVTYHI 404
Query: 441 YAMGRMENIWGPDCLEFKPERWL-KDGV----FVPKCPFKYPVFQAGSRVCLGKELAIVE 495
YAMGR E IWGPD EF+PERWL +D V FV + YPVFQAG RVC+GKE+A ++
Sbjct: 405 YAMGRSEKIWGPDWAEFRPERWLSRDEVGKWSFVGIDYYSYPVFQAGPRVCIGKEMAFLQ 464
Query: 496 MKSVVASLVKRFD-VRVVGPNQEPQFAPGLTASFRGGLPVKIYERT 540
MK VVA ++ RF V + EP++ T+ +GG PVKI +R+
Sbjct: 465 MKRVVAGIMGRFRVVPAMVEGIEPEYTAHFTSVMKGGFPVKIEKRS 510
>C862_ARATH (O23066) Cytochrome P450 86A2 (EC 1.14.-.-)
Length = 553
Score = 310 bits (793), Expect = 8e-84
Identities = 173/446 (38%), Positives = 263/446 (58%), Gaps = 36/446 (8%)
Query: 114 TITSNPENVEYILKTNFNNYPKGKQFSTILGDLLGRGIFNVDGHSWKFQRKMASLELGSV 173
T+T +P+N+E++LKT F+NYPKG + + D LG+GIFN DG +W FQRK A+LE +
Sbjct: 82 TVTCDPKNIEHMLKTRFDNYPKGPTWQAVFHDFLGQGIFNSDGDTWLFQRKTAALEFTTR 141
Query: 174 VIRSYAMELVIEEIKTRLLPLIASVAEKKTASKADNTSEDVLLDMQDILRRFSFDNICKF 233
+R V IK R P++ + A N E V D+QD++ R +FDNIC
Sbjct: 142 TLRQAMGRWVNRGIKLRFCPILET---------AQNNYEPV--DLQDLILRLTFDNICGL 190
Query: 234 SFGLDPCCLVPSLPVSNLANAFDLSSTLSAQRALTASPLIWKMKRFFNIGSEKKLKEAI- 292
+FG D P LP + A+AFD ++ S QR + +W++K++ +G E L ++
Sbjct: 191 AFGKDTRTCAPGLPENGFASAFDRATEASLQRFILPE-FLWRLKKWLGLGLEVSLSRSLG 249
Query: 293 -------KIVNDLANEMIKQRREIENGVESRKDLLSRFMGALN-SHDDEYLRDIVVSFLL 344
++N E++ QR E+GV+ DLLSRFM + S+ + +LR + ++F+L
Sbjct: 250 EIDGYLDAVINTRKQELLSQR---ESGVQRHDDLLSRFMKKKDQSYSETFLRHVALNFIL 306
Query: 345 AGRDTVASALTGFFILLSKNPKVEEKIRVELDRVMNPNQ---------ECATFEQTREMH 395
AGRDT + AL+ FF L++ +P VE+KI E+ V+ + E F++ +
Sbjct: 307 AGRDTSSVALSWFFWLITTHPTVEDKIVREICSVLIETRGTDVSSWTAEPLEFDEVDRLV 366
Query: 396 YLNGAIHESMRLFPPVQFDSKFALEDDVLPDGTFIKKGSRVTYHPYAMGRMENIWGPDCL 455
YL A+ E++RL+P V DSK + DD+LPDGTF+ GS VTY YA GRM++ WG DCL
Sbjct: 367 YLKAALSETLRLYPSVPEDSKHVVNDDILPDGTFVPAGSSVTYSIYAAGRMKSTWGEDCL 426
Query: 456 EFKPERWLK--DGVFVPKCPFKYPVFQAGSRVCLGKELAIVEMKSVVASLVKRFDVRVVG 513
EFKPERW+ DG FV +++ F AG R+CLGK+LA ++MK++ A+++ R + V
Sbjct: 427 EFKPERWISPDDGKFVNHDQYRFVAFNAGPRICLGKDLAYLQMKTIAAAVLLRHRL-TVA 485
Query: 514 PNQEPQFAPGLTASFRGGLPVKIYER 539
P + + LT + GL V +++R
Sbjct: 486 PGHKVEQKMSLTLFMKNGLLVNVHKR 511
>C861_ARATH (P48422) Cytochrome P450 86A1 (EC 1.14.-.-) (CYPLXXXVI)
(P450-dependent fatty acid omega-hydroxylase)
Length = 513
Score = 287 bits (735), Expect = 4e-77
Identities = 172/442 (38%), Positives = 253/442 (56%), Gaps = 34/442 (7%)
Query: 114 TITSNPENVEYILKTNFNNYPKGKQFSTILGDLLGRGIFNVDGHSWKFQRKMASLELGSV 173
T+T +P+NVE+ILKT F+NYPKG + DLLG+GIFN DG +W QRK A+LE +
Sbjct: 85 TVTCHPKNVEHILKTRFDNYPKGPMWRAAFHDLLGQGIFNSDGDTWLMQRKTAALEFTTR 144
Query: 174 VIRSYAMELVIEEIKTRLLPLIASVAEKKTASKADNTSEDVLLDMQDILRRFSFDNICKF 233
+R V IK RL ++ + +D+QD+ R +FDNIC
Sbjct: 145 TLRQAMARWVNGTIKNRLWLILDRAVQNNKP-----------VDLQDLFLRLTFDNICGL 193
Query: 234 SFGLDPCCLVPSLPVSNLANAFDLSSTLSAQRALTASPLIWKMKRFFNIGSEKKLKEAIK 293
+FG DP L LP + + AFD ++ + +R L +W++++ IGSE KLK++++
Sbjct: 194 TFGKDPETLSLDLPDNPFSVAFDTATEATLKRLLYTG-FLWRIQKAMGIGSEDKLKKSLE 252
Query: 294 IVNDLANEMIKQRREIENGVESRKDLLSRFMGALNSHDD----EYLRDIVVSFLLAGRDT 349
+V N+ I R+ + DLLSRF+ + + + + L+ I ++F+LAGRDT
Sbjct: 253 VVETYMNDAIDARKNSPSD-----DLLSRFLKKRDVNGNVLPTDVLQRIALNFVLAGRDT 307
Query: 350 VASALTGFFILLSKNPKVEEKIRVELDRVMNPN---------QECATFEQTREMHYLNGA 400
+ AL+ FF L+ N +VE KI EL V+ +E F++ + YL A
Sbjct: 308 SSVALSWFFWLVMNNREVETKIVNELSMVLKETRGNDQEKWTEEPLEFDEADRLVYLKAA 367
Query: 401 IHESMRLFPPVQFDSKFALEDDVLPDGTFIKKGSRVTYHPYAMGRMENIWGPDCLEFKPE 460
+ E++RL+P V D K+ ++DDVLPDGTF+ +GS VTY Y++GRM+ IWG DCLEF+PE
Sbjct: 368 LAETLRLYPSVPQDFKYVVDDDVLPDGTFVPRGSTVTYSIYSIGRMKTIWGEDCLEFRPE 427
Query: 461 RWL-KDG--VFVPKCPFKYPVFQAGSRVCLGKELAIVEMKSVVASLVKRFDVRVVGPNQE 517
RWL DG PK +K+ F AG R CLGK+LA +MKSV ++++ R+ V V P
Sbjct: 428 RWLTADGERFETPKDGYKFVAFNAGPRTCLGKDLAYNQMKSVASAVLLRYRVFPV-PGHR 486
Query: 518 PQFAPGLTASFRGGLPVKIYER 539
+ LT + GL V + R
Sbjct: 487 VEQKMSLTLFMKNGLRVYLQPR 508
>CP5D_CANMA (P16141) Cytochrome P450 52A4 (EC 1.14.14.-) (CYPLIIA4)
(Alkane-inducible P450-ALK3-A) (P450-CM2)
Length = 537
Score = 165 bits (417), Expect = 3e-40
Identities = 140/492 (28%), Positives = 223/492 (44%), Gaps = 64/492 (13%)
Query: 74 TCKTFLTMSWSNKFVNLVDYYTHLLQESPTGTIHVHVLGNTI--TSNPENVEYILKTNFN 131
T F W+NKF L+ T+ + ++G I T++PENV+ IL T FN
Sbjct: 82 TVMEFACNVWNNKF---------LVLNGNVRTVGLRIMGLNIIETTDPENVKAILATQFN 132
Query: 132 NYPKGKQFSTILGDLLGRGIFNVDGHSWKFQRKMASLELGSVVIRSYAMELVIEEIKTRL 191
++ G + L LLG GIF +DG WK R M + +A E V +L
Sbjct: 133 DFSLGTRHD-FLYSLLGDGIFTLDGAGWKHSRAMLRPQ--------FAREQVAH---VKL 180
Query: 192 LPLIASVAEKKTASKADNTSEDVLLDMQDILRRFSFDNICKFSFGLDPCCL-------VP 244
L V K T D+Q++ R + D+ +F FG L VP
Sbjct: 181 LEPHVQVLFKHVRKSQGKT-----FDIQELFFRLTVDSSTEFLFGGSVESLRDASIGMVP 235
Query: 245 SLPV----SNLANAFDLSSTLSAQRALTASPLIWKMKRFFNIGSEKKLKEAIKIVNDLAN 300
S A+AF+ S T +A R L +++F+ I + K ++IK V+ A+
Sbjct: 236 STKNIAGREEFADAFNYSQTYNAYRFL--------LQQFYWILNGSKFNKSIKTVHKFAD 287
Query: 301 EMIKQRREI-ENGVESRKDLLSRFMGALNSHDDEYLRDIVVSFLLAGRDTVASALTGFFI 359
+++ + ++ +E ++ + + A + D + LRD +++ L+AGRDT A L+ F
Sbjct: 288 FYVQKALSLTDDDLEKQEGYVFLYELAKQTRDPKVLRDQLLNILVAGRDTTAGLLSFLFF 347
Query: 360 LLSKNPKVEEKIRVELDRVMNPNQEC----ATFEQTREMHYLNGAIHESMRLFPPVQFDS 415
LS+NP V EK++ E+ ++ TFE + YL ++E++R++P V +
Sbjct: 348 ELSRNPTVFEKLKEEIHNRFGAKEDARVEEITFESLKLCEYLKACVNEALRVYPSVPHNF 407
Query: 416 KFALEDDVLPDG--------TFIKKGSRVTYHPYAMGRMENIWGPDCLEFKPERWLKDGV 467
+ A + LP G IKKG V Y A R +I+G D F+PERW +
Sbjct: 408 RVATRNTTLPRGGGKDGMSPIAIKKGQNVMYTISATHRDPSIYGEDANVFRPERWFEPE- 466
Query: 468 FVPKCPFKYPVFQAGSRVCLGKELAIVEMKSVVASLVKRFDVRVVGPNQE--PQFAPGLT 525
K + Y F G R+CLG++ A+ E V L++ F N P+ LT
Sbjct: 467 -TRKLGWAYVPFNGGPRICLGQQFALTEASYVTVRLLQEFHTLTQDANTRYPPRLQNSLT 525
Query: 526 ASFRGGLPVKIY 537
S G +++Y
Sbjct: 526 VSLCDGANIQMY 537
>CP5A_CANTR (P10615) Cytochrome P450 52A1 (EC 1.14.14.-) (CYPLIIA1)
(Alkane-inducible P450-ALK1)
Length = 543
Score = 160 bits (405), Expect = 8e-39
Identities = 135/469 (28%), Positives = 218/469 (45%), Gaps = 55/469 (11%)
Query: 97 LLQESPTGTIHVHVLGNTI--TSNPENVEYILKTNFNNYPKGKQFSTILGDLLGRGIFNV 154
++ + TI + +LG + T +PENV+ IL T FN++ G + L LLG GIF +
Sbjct: 99 IVSDPKAKTIGLKILGIPLIETKDPENVKAILATQFNDFSLGTRHD-FLYSLLGDGIFTL 157
Query: 155 DGHSWKFQRKMASLELGSVVIRSYAMELVIEEIKTRLLPLIASVAEKKTASKADNTSEDV 214
DG WK R M + +A E V +LL V K T
Sbjct: 158 DGAGWKHSRTMLRPQ--------FAREQVSH---VKLLEPHMQVLFKHIRKHHGQT---- 202
Query: 215 LLDMQDILRRFSFDNICKFSFGLDPCCL----VPSLPVSN-------LANAFDLSSTLSA 263
D+Q++ R + D+ +F G L V P + A+AF+ S T A
Sbjct: 203 -FDIQELFFRLTVDSATEFLLGESAESLRDESVGLTPTTKDFDGRNEFADAFNYSQTNQA 261
Query: 264 QRALTASPLIWKMKRFFNIGSEKKLKEAIKIVNDLANEMIKQRREI-ENGVESRKDLLSR 322
R L +++ + I + + +++I IV+ A+ +++ E+ + +E ++ +
Sbjct: 262 YRFL--------LQQMYWILNGSEFRKSIAIVHKFADHYVQKALELTDEDLEKKEGYVFL 313
Query: 323 FMGALNSHDDEYLRDIVVSFLLAGRDTVASALTGFFILLSKNPKVEEKIRVELDRVMNPN 382
F A + D + LRD +++ L+AGRDT A L+ F LS+NP++ K+R E++
Sbjct: 314 FELAKQTRDPKVLRDQLLNILVAGRDTTAGLLSFLFFELSRNPEIFAKLREEIENKFGLG 373
Query: 383 QEC----ATFEQTREMHYLNGAIHESMRLFPPVQFDSKFALEDDVLPDG--------TFI 430
Q+ +FE + YL I+E++R++P V + + A + LP G I
Sbjct: 374 QDARVEEISFETLKSCEYLKAVINETLRIYPSVPHNFRVATRNTTLPRGGGEGGLSPIAI 433
Query: 431 KKGSRVTYHPYAMGRMENIWGPDCLEFKPERWLKDGVFVPKCPFKYPVFQAGSRVCLGKE 490
KKG V Y A R ++I+G D F+PERW + K + Y F G R+CLG++
Sbjct: 434 KKGQVVMYTILATHRDKDIYGEDAYVFRPERWFEPE--TRKLGWAYVPFNGGPRICLGQQ 491
Query: 491 LAIVEMKSVVASLVKRFDVRVVGPNQE--PQFAPGLTASFRGGLPVKIY 537
A+ E V L++ F PN E P+ LT S G V++Y
Sbjct: 492 FALTEASYVTVRLLQEFGNLKQDPNTEYPPKLQNTLTLSLFEGAEVQMY 540
>CP5E_CANMA (P24458) Cytochrome P450 52A5 (EC 1.14.14.-) (CYPLIIA5)
(Alkane-inducible P450-ALK2-A) (CYP52A3-B)
Length = 523
Score = 160 bits (404), Expect = 1e-38
Identities = 125/447 (27%), Positives = 209/447 (45%), Gaps = 55/447 (12%)
Query: 90 LVDYYTHLLQESPTGTIHVHVLGN---TITSNPENVEYILKTNFNNYPKGKQFSTILGDL 146
L DY E P + ++ V G +T +PEN++ +L T FN++ G + + L
Sbjct: 74 LADYADQTFDEYPHHSFYMTVAGMLKIVLTVDPENIKAVLATQFNDFALGARHAHF-DPL 132
Query: 147 LGRGIFNVDGHSWKFQRKMASLELGSVVIRSYAMELVIEEIKTRLLPLIASVAEKKTASK 206
LG GIF +DG WK R M +R I +K L P + +A++ +K
Sbjct: 133 LGDGIFTLDGEGWKHSRAM---------LRPQFAREQIAHVKA-LEPHVQVLAKQIKLNK 182
Query: 207 ADNTSEDVLLDMQDILRRFSFDNICKFSFG------LDPCCLVP---SLPV-SNLANAFD 256
+ D+Q++ RF+ D +F FG D VP ++P N A AF+
Sbjct: 183 GET------FDLQELFFRFTVDTATEFLFGESVHSLYDEKLGVPPPNNIPGRENFAKAFN 236
Query: 257 LSSTLSAQRALTASPLIWKMKRFFNIGSEKKLKEAIKIVNDLANEMIKQR---REIENGV 313
S A R + + F+ + + K+ ++ V+ LA + + E E
Sbjct: 237 TSQHYLATRTYS--------QMFYFLTNPKEFRDCNAKVHKLAQYFVNKALDASEDEVAE 288
Query: 314 ESRKDLLSRFMGALNSHDDEYLRDIVVSFLLAGRDTVASALTGFFILLSKNPKVEEKIRV 373
+S+ + + + D + L+D +++ ++AGRDT A L+ L++NPK+ K+R
Sbjct: 289 KSKGGYVFLYELVKQTRDPKVLQDQLLNIMVAGRDTTAGLLSFAMFELARNPKIWNKLRE 348
Query: 374 ELDRVMNPNQECA----TFEQTREMHYLNGAIHESMRLFPPVQFDSKFALEDDVLP---- 425
E++ +E +FE ++ YL ++E++R++P V + + A D LP
Sbjct: 349 EIEVNFGLGEEARVDEISFETLKKCEYLKAVLNETLRMYPSVPVNFRTATRDTTLPRGGG 408
Query: 426 -DGT---FIKKGSRVTYHPYAMGRMENIWGPDCLEFKPERWLKDGVFVPKCPFKYPVFQA 481
DGT F+ KGS V Y Y R+E +G D EF+PERW + K + Y F
Sbjct: 409 KDGTSPIFVPKGSSVVYTVYKTHRLEEYYGKDAYEFRPERWFEPS--TRKLGWAYVPFNG 466
Query: 482 GSRVCLGKELAIVEMKSVVASLVKRFD 508
G R+CLG++ A+ E V+ L + F+
Sbjct: 467 GPRICLGQQFALTEASYVITRLAQMFE 493
>CP5B_CANTR (P30607) Cytochrome P450 52A2 (EC 1.14.14.-) (CYPLIIA2)
(Alkane-inducible P450-ALK2)
Length = 522
Score = 159 bits (401), Expect = 2e-38
Identities = 132/462 (28%), Positives = 211/462 (45%), Gaps = 53/462 (11%)
Query: 102 PTGTIHVHVLGNTITSNPENVEYILKTNFNNYPKGKQFSTILGDLLGRGIFNVDGHSWKF 161
PT T + + T P+N++ IL T FN++ G + S LLG GIF +DG WK
Sbjct: 88 PTFTFPIFSVLIISTLEPDNIKAILATQFNDFSLGTRHSHF-APLLGDGIFTLDGAGWKH 146
Query: 162 QRKMASLELGSVVIRSYAMELVIEEIKTRLLPLIASVAEKKTASKADNTSEDVLLDMQDI 221
R M + +A E V +LL V K T D+Q++
Sbjct: 147 SRSMLRPQ--------FAREQVSH---VKLLEPHMQVFFKHIRKHHGQT-----FDIQEL 190
Query: 222 LRRFSFDNICKFSFGLDPCCLVP-SLPVSN----------LANAFDLSSTLSAQRALTAS 270
R + D+ +F FG L S+ + N A+AF+ S A RAL
Sbjct: 191 FFRLTVDSATEFLFGESVESLRDESIGMLNDALDFDGKAGFADAFNYSQNYLASRAL--- 247
Query: 271 PLIWKMKRFFNIGSEKKLKEAIKIVNDLANEMIKQRREIE-NGVESRKDLLSRFMGALNS 329
M++ + I + KK KE V+ A+ +++ E+ + +E + + + +
Sbjct: 248 -----MQQMYWILNGKKFKECNAKVHKFADYYVEKALELTPDQLEKQDGYVFLYELVKQT 302
Query: 330 HDDEYLRDIVVSFLLAGRDTVASALTGFFILLSKNPKVEEKIRVELDRVMNPNQEC---- 385
D + LRD +++ L+AGRDT A L+ F L++ P+V K+R E++ Q+
Sbjct: 303 RDRQVLRDQLLNILVAGRDTTAGLLSFVFFELARTPRVANKLREEIEDKFGLGQDARVEE 362
Query: 386 ATFEQTREMHYLNGAIHESMRLFPPVQFDSKFALEDDVLPDG--------TFIKKGSRVT 437
+FE + YL ++E +RL+P V + + A + LP G ++KG V
Sbjct: 363 ISFESLKSCEYLKAVLNECLRLYPSVPQNFRVATRNTTLPRGGGKDGLSPVLVRKGQTVM 422
Query: 438 YHPYAMGRMENIWGPDCLEFKPERWLKDGVFVPKCPFKYPVFQAGSRVCLGKELAIVEMK 497
Y YA R + I+G D LEF+PERW + K + + F G R+CLG++ A+ E
Sbjct: 423 YSVYAAHRNKQIYGEDALEFRPERWFEPE--TKKLGWAFLPFNGGPRICLGQQFALTEAS 480
Query: 498 SVVASLVKRFDVRVVGPNQE--PQFAPGLTASFRGGLPVKIY 537
V L++ F + PN E P+ LT S G +++Y
Sbjct: 481 YVTVRLLQEFSHLTMDPNTEYSPKKMSHLTMSLFDGANIQMY 522
>CP5J_CANMA (Q12588) Cytochrome P450 52A10 (EC 1.14.14.-)
(CYPLIIA10) (Alkane-inducible P450-ALK7)
Length = 519
Score = 155 bits (392), Expect = 3e-37
Identities = 126/446 (28%), Positives = 201/446 (44%), Gaps = 53/446 (11%)
Query: 116 TSNPENVEYILKTNFNNYPKGKQFSTILGDLLGRGIFNVDGHSWKFQRKMASLELGSVVI 175
T +PEN++ +L T FN Y G++ + L LLG+GIF +DG+ WK R M +
Sbjct: 99 TKDPENIKAMLATQFNEYTLGQRLN-FLAPLLGKGIFTLDGNGWKHSRAMLRPQFS---- 153
Query: 176 RSYAMELVIEEIKTRLLPLIASVAEKKTASKADNTSEDVLLDMQDILRRFSFDNICKFSF 235
R + + E +LL KK K T D+Q++ RF+ D+ +F F
Sbjct: 154 RDQIGHVKMLEPHFQLL--------KKHIIKNKGT----FFDIQELFFRFTVDSATEFLF 201
Query: 236 GLDPCCL-----------VPSLPVSNLANAFDLSSTLSAQRALTASPLIWKMKRFFNIGS 284
G L + + A AF+ S + R L ++ + + +
Sbjct: 202 GESVSSLKDESIGYDQEEIDFAGRKDFAEAFNKSQVYLSTRTL--------LQLLYWLVN 253
Query: 285 EKKLKEAIKIVNDLANEMIKQR-REIENGVESRKDLLSRFMGALNSHDDEYLRDIVVSFL 343
K KIV+ ++ IK+ +E + + A + D LRD ++ L
Sbjct: 254 SADFKRCNKIVHKFSDYYIKKALTATPEELEKHSSYIFLYELAKQTRDPIVLRDQSLNIL 313
Query: 344 LAGRDTVASALTGFFILLSKNPKVEEKIRVELDRVMNPNQ----ECATFEQTREMHYLNG 399
LAGRDT A L+ L +NP+V K+R E+ + E +FE + YL
Sbjct: 314 LAGRDTTAGLLSFAVFELGRNPEVWSKLRQEIGHKFGLDSYSRVEDISFELLKLCEYLKA 373
Query: 400 AIHESMRLFPPVQFDSKFALEDDVLPDG--------TFIKKGSRVTYHPYAMGRMENIWG 451
++E++RL+P V +++FA ++ LP G ++KG V Y YA+ R E +G
Sbjct: 374 VLNETLRLYPSVPRNARFAAKNTTLPHGGGPDGMSPILVRKGQTVMYSVYALQRDEKYYG 433
Query: 452 PDCLEFKPERWLKDGVFVPKCPFKYPVFQAGSRVCLGKELAIVEMKSVVASLVKRFDVRV 511
D EF+PERW + V K + + F G R+CLG++ A+ E V+A L++ F+
Sbjct: 434 KDANEFRPERWFEPE--VRKLGWAFLPFNGGPRICLGQQFALTEASYVLARLIQSFETLE 491
Query: 512 VGPN--QEPQFAPGLTASFRGGLPVK 535
+ P P LT G PV+
Sbjct: 492 LSPEAAYPPAKLSHLTMCLFDGTPVR 517
>CP5M_DEBHA (Q9Y758) Cytochrome P450 52A13 (EC 1.14.14.-) (Alkane
hydroxylase 2) (Alkane-inducible p450alk 2) (DH-ALK2)
Length = 519
Score = 154 bits (388), Expect = 7e-37
Identities = 128/503 (25%), Positives = 228/503 (44%), Gaps = 82/503 (16%)
Query: 52 LLFSFF-SFLLFISRIKPWCNCNTCKTFLTMSWSN-----------KFVNLVDYYTHLLQ 99
LL SFF + + ++R K NC + ++W + + L+D+ +
Sbjct: 22 LLVSFFIAHKISVARFKATHNCAASPEYYKVNWFSLPLLYRLIQVKREGRLLDFAQKIYD 81
Query: 100 ESPTGTIHVHVLGNT--ITSNPENVEYILKTNFNNYPKGKQFSTILGDLLGRGIFNVDGH 157
+ T + ++G IT +PEN++ +L T FN++ G + + LLG GIF +DG+
Sbjct: 82 DVKALTFVIKIVGVPVIITRDPENMKAVLATQFNDFALGTRHAHFK-PLLGDGIFTLDGN 140
Query: 158 SWKFQRKMASLELG-SVVIRSYAMELVIEEIKTRLLPLIASVAEKKTASKADNTSEDVLL 216
WK R M + V A+E ++ + + +A+ +T +
Sbjct: 141 GWKQSRSMLRPQFSREQVAHVQALEPHLQRLAKHI-----RLADGET------------I 183
Query: 217 DMQDILRRFSFDNICKFSFGLDPCCL----VPSLPV------SNLANAFDLSSTLSAQRA 266
++QD+ + + D +F FG L + P S+ AN+F+ + T RA
Sbjct: 184 NIQDLFFKLTVDTATEFLFGQSVYSLKDAAINDPPTEDFDGRSSFANSFNTAQTYLGTRA 243
Query: 267 LTASPLIWKMKRFFNIGSEKKLKEAIKIVNDLANEMIKQ---------RREIENGVESRK 317
++ F+ I + ++ K V+D +++ ++ ENG
Sbjct: 244 Y--------LQMFYFIVNNSDFRKCCKQVHDFTRFYVQKGLDMTPEELEKKSENGYVFLY 295
Query: 318 DLLSRFMGALNSHDDEYLRDIVVSFLLAGRDTVASALTGFFILLSKNPKVEEKIRVELDR 377
+L+ + + D + L+D +++ LLAGRDT A L+ F L+++P+V K++ E+
Sbjct: 296 ELVKQ------TRDPKVLQDQLLNILLAGRDTTAGLLSFTFFELARHPRVFNKLKEEIYE 349
Query: 378 VMNPNQECA----TFEQTREMHYLNGAIHESMRLFPPVQFDSKFALEDDVLPDG------ 427
+ TFE ++ YL ++E +RL+P V + + A + LP G
Sbjct: 350 AFGKGDDARVSEITFESLKKCEYLKWVMNEMLRLYPSVPVNFRVATKRTTLPRGGGPDGN 409
Query: 428 --TFIKKGSRVTYHPYAMGRMENIWGPDCLEFKPERWLKDGVFVPKCPFKYPVFQAGSRV 485
++ KG+ V Y Y+ RME +G D EFKPERW + K + Y F G R+
Sbjct: 410 SPIYVGKGTTVAYSVYSTHRMEEYYGKDADEFKPERWAES----RKLGWAYVPFNGGPRI 465
Query: 486 CLGKELAIVEMKSVVASLVKRFD 508
CLG++ A+ E +V L++ FD
Sbjct: 466 CLGQQFALTEASYIVTRLLQMFD 488
>CP5K_CANMA (Q12589) Cytochrome P450 52A11 (EC 1.14.14.-)
(CYPLIIA11) (Alkane-inducible P450-ALK8)
Length = 519
Score = 153 bits (387), Expect = 1e-36
Identities = 127/447 (28%), Positives = 206/447 (45%), Gaps = 53/447 (11%)
Query: 116 TSNPENVEYILKTNFNNYPKGKQFSTILGDLLGRGIFNVDGHSWKFQRKMASLELGSVVI 175
T +PEN++ +L T FN++ G++ S LLG+GIF +DG WK R M +
Sbjct: 99 TKDPENIKAMLATQFNDFTLGQRLS-YFAPLLGKGIFTLDGEGWKHSRAMLRPQFS---- 153
Query: 176 RSYAMELVIEEIKTRLLPLIASVAEKKTASKADNTSEDVLLDMQDILRRFSFDNICKFSF 235
R + + E +LL KK K ++ D+Q++ RF+ D+ +F F
Sbjct: 154 RDQVGHVKMLEPHFQLL--------KKHIIK----NKGSFFDIQELFFRFTVDSATEFLF 201
Query: 236 GLDPCCL-----------VPSLPVSNLANAFDLSSTLSAQRALTASPLIWKMKRFFNIGS 284
G L + + A AF+ S + R+L ++ + + +
Sbjct: 202 GESVSSLKDESIGYDQEEIDFAGRKDFAEAFNKSQVYLSTRSL--------LQLLYWLVN 253
Query: 285 EKKLKEAIKIVNDLANEMIKQR-REIENGVESRKDLLSRFMGALNSHDDEYLRDIVVSFL 343
K KIV+ ++ IK+ +E + + A + D LRD ++ L
Sbjct: 254 SSDFKRCNKIVHKFSDYYIKKALTATPEELEKHSSYIFLYELAKQTRDPIVLRDQSLNIL 313
Query: 344 LAGRDTVASALTGFFILLSKNPKVEEKIRVEL-DRV-MNPNQ--ECATFEQTREMHYLNG 399
LAGRDT A L+ L +NP+V K+R E+ D+ ++P+ E +FE + YL
Sbjct: 314 LAGRDTTAGLLSFAVFELGRNPEVWSKLREEIGDKFGLDPDSRIEDISFELLKLCEYLKA 373
Query: 400 AIHESMRLFPPVQFDSKFALEDDVLPDG--------TFIKKGSRVTYHPYAMGRMENIWG 451
I+E++RL+P V + +FA + LP G ++KG V Y YA+ R E +G
Sbjct: 374 VINETLRLYPSVPRNGRFAAANTTLPHGGGPDGMSPILVRKGQTVMYSVYALQRDEKYYG 433
Query: 452 PDCLEFKPERWLKDGVFVPKCPFKYPVFQAGSRVCLGKELAIVEMKSVVASLVKRFDVRV 511
D EF+PERW + V K + + F G R+CLG++ A+ E V+ L++ F+
Sbjct: 434 KDANEFRPERWFEPE--VRKLGWAFLPFNGGPRICLGQQFALTEASYVLVRLIQSFETLE 491
Query: 512 VGPN--QEPQFAPGLTASFRGGLPVKI 536
+ P+ P LT G PV+I
Sbjct: 492 LSPDAPYPPAKLTHLTMCLFDGAPVRI 518
>CP5C_CANMA (P16496) Cytochrome P450 52A3 (EC 1.14.14.-) (CYPLIIA3)
(Alkane-inducible P450-ALK1-A) (P450-CM1) (CYP52A3-A)
(Cytochrome P-450ALK)
Length = 522
Score = 151 bits (381), Expect = 5e-36
Identities = 120/449 (26%), Positives = 203/449 (44%), Gaps = 59/449 (13%)
Query: 90 LVDYYTHLLQESPTGTIHVHVLGN---TITSNPENVEYILKTNFNNYPKGKQFSTILGDL 146
L DY + P + ++ V G T +PEN++ +L T FN++ G + + L
Sbjct: 73 LADYTDTTFDKYPNLSSYMTVAGVLKIVFTVDPENIKAVLATQFNDFALGARHAHF-DPL 131
Query: 147 LGRGIFNVDGHSWKFQRKMASLELGSVVIRSYAMELVIEEIKTRLLPLIASVAEKKTASK 206
LG GIF +DG WK R M +R I +K L P + +A++ +K
Sbjct: 132 LGDGIFTLDGEGWKLSRAM---------LRPQFAREQIAHVKA-LEPHVQILAKQIKLNK 181
Query: 207 ADNTSEDVLLDMQDILRRFSFDNICKFSFGLDPCCLVPS---LPV-------SNLANAFD 256
D+Q++ RF+ D +F FG L +P N A AF+
Sbjct: 182 GKT------FDLQELFFRFTVDTATEFLFGESVHSLYDEKLGIPAPNDIPGRENFAEAFN 235
Query: 257 LSSTLSAQRALTASPLIWKMKRFFNIGSEKKLKEAIKIVNDLANEMIKQ-----RREIEN 311
S A R + + F+ + + K+ ++ V+ LA + +E+E
Sbjct: 236 TSQHYLATRTYS--------QIFYWLTNPKEFRDCNAKVHKLAQYFVNTALNATEKEVEE 287
Query: 312 GVESRKDLLSRFMGALNSHDDEYLRDIVVSFLLAGRDTVASALTGFFILLSKNPKVEEKI 371
+S+ + + + D + L+D +++ ++AGRDT A L+ L++NPK+ K+
Sbjct: 288 --KSKGGYVFLYELVKQTRDPKVLQDQLLNIMVAGRDTTAGLLSFAMFELARNPKIWNKL 345
Query: 372 RVELDRVMNPNQECA----TFEQTREMHYLNGAIHESMRLFPPVQFDSKFALEDDVLPDG 427
R E++ E +FE ++ YL ++E++R++P V + + A D LP G
Sbjct: 346 REEVEVNFGLGDEARVDEISFETLKKCEYLKAVLNETLRMYPSVPINFRTATRDTTLPRG 405
Query: 428 --------TFIKKGSRVTYHPYAMGRMENIWGPDCLEFKPERWLKDGVFVPKCPFKYPVF 479
F+ KGS V Y Y R++ +G D EF+PERW + K + Y F
Sbjct: 406 GGKDGNSPIFVPKGSSVVYSVYKTHRLKQFYGEDAYEFRPERWFEPS--TRKLGWAYLPF 463
Query: 480 QAGSRVCLGKELAIVEMKSVVASLVKRFD 508
G R+CLG++ A+ E V+A L + F+
Sbjct: 464 NGGPRICLGQQFALTEASYVIARLAQMFE 492
>CP5F_CANTR (P30608) Cytochrome P450 52A6 (EC 1.14.14.-) (CYPLIIA6)
(Alkane-inducible P450-ALK3)
Length = 524
Score = 149 bits (376), Expect = 2e-35
Identities = 129/474 (27%), Positives = 211/474 (44%), Gaps = 63/474 (13%)
Query: 92 DYYTHLLQESPTGTIHVHVLGNTITSNPENVEYILKTNFNNYPKGKQFSTILGDLLGRGI 151
DY H S G + + +T EN++ +L T F ++ G + + LLG GI
Sbjct: 85 DYPNHTFYMSIIGALKI-----VLTVIQENIKAVLATQFTDFSLGTRHAHFY-PLLGDGI 138
Query: 152 FNVDGHSWKFQRKMASLELGSVVIRSYAMELVIEEIKTRLLPLIASVAEKKTASKADNTS 211
F +DG WK R M +R I +K L P I +A++ +K
Sbjct: 139 FTLDGEGWKHSRAM---------LRPQFARDQIGHVKA-LEPHIQILAKQIKLNKGKT-- 186
Query: 212 EDVLLDMQDILRRFSFDNICKFSFGLDPCCLVPS---LPV-------SNLANAFDLSSTL 261
D+Q++ RF+ D +F FG L +P N A AF+ S
Sbjct: 187 ----FDIQELFFRFTVDTATEFLFGESVHSLYDEKLGIPTPNEIPGRDNFATAFNTSQHY 242
Query: 262 SAQRALTASPLIWKMKRFFNIGSEKKLKEAIKIVNDLANEMIKQR-----REIENGVESR 316
A R + + F+ + + K+ ++ V+ LA + + EIE +S+
Sbjct: 243 LATRTYSQT--------FYFLTNPKEFRDCNAKVHYLAKYFVNKALNFTPEEIEE--KSK 292
Query: 317 KDLLSRFMGALNSHDDEYLRDIVVSFLLAGRDTVASALTGFFILLSKNPKVEEKIRVELD 376
+ + + D + L+D +++ ++AGRDT A L+ L+++P++ K+R E++
Sbjct: 293 SGYVFLYELVKQTRDPKVLQDQLLNIMVAGRDTTAGLLSFAMFELARHPEIWSKLREEIE 352
Query: 377 RVMNPNQECA----TFEQTREMHYLNGAIHESMRLFPPVQFDSKFALEDDVLPDG----- 427
+E TFE + YL ++E++R++P V +S+ A D LP G
Sbjct: 353 VNFGVGEESRVEEITFESLKRCEYLKAILNETLRMYPSVPVNSRTATRDTTLPRGGGPNG 412
Query: 428 ---TFIKKGSRVTYHPYAMGRMENIWGPDCLEFKPERWLKDGVFVPKCPFKYPVFQAGSR 484
FI KGS V Y Y R+E +G D +F+PERW + K + Y F G R
Sbjct: 413 TDPIFIPKGSTVAYIVYKTHRLEEYYGKDADDFRPERWFEPS--TKKLGWAYVPFNGGPR 470
Query: 485 VCLGKELAIVEMKSVVASLVKRFDVRVVGPNQE--PQFAPGLTASFRGGLPVKI 536
+CLG++ A+ E V+ LV+ F+ P+ E P LT S G+ VK+
Sbjct: 471 ICLGQQFALTEASYVITRLVQMFETVSSPPDVEYPPPKCIHLTMSHDDGVFVKM 524
>CP5T_CANMA (Q12585) Cytochrome P450 52D1 (EC 1.14.14.-) (CYPLIID1)
(Alkane-inducible P450-ALK4)
Length = 505
Score = 148 bits (373), Expect = 4e-35
Identities = 126/471 (26%), Positives = 207/471 (43%), Gaps = 46/471 (9%)
Query: 84 SNKFVNLVDYYTHLLQESPTGTIHVHVLGNTI--TSNPENVEYILKTNFNNYPKGKQFST 141
+N L+++ SP T G I T +P N++ +L F+ + G +++
Sbjct: 57 ANNQGRLIEFSVKRFLSSPHQTFMNRAFGIPIILTRDPVNIKAMLAVQFDEFSLGLRYNQ 116
Query: 142 ILGDLLGRGIFNVDGHSWKFQRKMASLELGSVVIRSYAMELVIEEIKTRLLPLIASVAEK 201
LLG GIF DG WK R +++R ++ + + RL P ++ +K
Sbjct: 117 F-EPLLGNGIFTSDGEPWKHSR---------IMLRPQFIKSQVSHVN-RLEPHF-NLLQK 164
Query: 202 KTASKADNTSEDVLLDMQDILRRFSFDNICKFSFGLDPCCLVPSLPVSNLANAFDLSSTL 261
++ DN D+Q + RF+ D +F FG L AF S +
Sbjct: 165 NITAQTDN-----YFDIQTLFFRFTLDTATEFLFGQSVHSLNDGENSLQFLEAFTKSQAI 219
Query: 262 SAQRALTASPLIWKMKRFFNIGSEKKLKEAIKIVNDLANEMIKQRREIENGVESRKDLLS 321
A RA + + + K ++ K+V D + + + + N S D L
Sbjct: 220 LATRA--------NLHELYFLADGIKFRQYNKMVQDFSQRCVDKVLNMSN---SEIDKLD 268
Query: 322 RFMGALN----SHDDEYLRDIVVSFLLAGRDTVASALTGFFILLSKNPKVEEKIRVELDR 377
R+ + + + LRD ++ LLAGRDT AS L+ F L+ N + K+R E+
Sbjct: 269 RYFFLYEMVKITRNPQVLRDQCLNILLAGRDTTASLLSFAFFELALNEPIWIKLRTEVLH 328
Query: 378 VMNPNQECATFEQTR-EMHYLNGAIHESMRLFPPVQFDSKFALEDDVLPDG--------T 428
V + E TF+ + + YL +HE++RL+P V +++F+ ++ LP G
Sbjct: 329 VFQTSLELITFDLLKTKCPYLQAILHETLRLYPSVPRNARFSKKNTTLPHGGGVDGMSPI 388
Query: 429 FIKKGSRVTYHPYAMGRMENIWGPDCLEFKPERWLKDGVFVPKCPFKYPVFQAGSRVCLG 488
IKKG V Y A E + D L F+PERW ++ + + Y F G R+CLG
Sbjct: 389 LIKKGQPVAYFICATHVDEKFYTKDALIFRPERWCEEPLIKKNLAWSYLPFNGGPRICLG 448
Query: 489 KELAIVEMKSVVASLVKRFDVRVVGPNQ---EPQFAPGLTASFRGGLPVKI 536
++ A+ E V+ L + + + PN P+ LT S G+ VKI
Sbjct: 449 QQFALTEASYVLTRLAQCYTKISLQPNSFEYPPKKQVHLTMSLLDGVHVKI 499
>CP5L_DEBHA (Q9Y757) Cytochrome P450 52A12 (EC 1.14.14.-) (Alkane
hydroxylase 1) (Alkane-inducible p450alk 1) (DH-ALK2)
Length = 519
Score = 143 bits (360), Expect = 1e-33
Identities = 125/446 (28%), Positives = 193/446 (43%), Gaps = 55/446 (12%)
Query: 90 LVDYYTHLLQESPTGTIHVHVLGNTI--TSNPENVEYILKTNFNNYPKGK---QFSTILG 144
LV++ + T + G + T NPEN++ +L T F+++ G QF +LG
Sbjct: 70 LVNFIKERFETVGKDTFSFRIAGTPVISTKNPENIKALLATQFSDFALGTRHAQFKPLLG 129
Query: 145 DLLGRGIFNVDGHSWKFQRKMASLELGSVVIRSYAMELVIEEIKTRLLPLIASVAEKKTA 204
D GIF +DG WK R M +R + +K+ L P I +A+
Sbjct: 130 D----GIFTLDGSGWKHSRAM---------LRPQFAREQVAHVKS-LEPHIQMLAKHVRR 175
Query: 205 SKADNTSEDVLLDMQDILRRFSFDNICKFSFGLDPCCL-----------VPSLPVSNLAN 253
+K D+Q + R + D+ +F FG L V + A
Sbjct: 176 AKGG------AFDVQSLFFRLTVDSATEFLFGESVESLQDESIGMAKDAVDFDGKAGFAE 229
Query: 254 AFDLSSTLSAQRALTASPLIWKMKRFFNIGSEKKLKEAIKIVNDLANEMIKQRREIENGV 313
AF+ + + R+L + F +EK K A V N E+E
Sbjct: 230 AFNTAQVYLSIRSLAQKAYFLVNNKEFRSSNEKVHKFADYYVQKALNS---SPEELEK-- 284
Query: 314 ESRKDLLSRFMGALNSHDDEYLRDIVVSFLLAGRDTVASALTGFFILLSKNPKVEEKIRV 373
S+ + + + D LRD +++ LLAGRDT A L+ F L++NP+V K++
Sbjct: 285 HSQDGYIFLYELVKQTRDPHVLRDQLLNILLAGRDTTAGLLSFTFYELARNPQVWLKLKE 344
Query: 374 ELDRVMNPNQECA----TFEQTREMHYLNGAIHESMRLFPPVQFDSKFALEDDVLPDG-- 427
E+ + TFE ++ YL ++E +RL+P V + + A +D LP G
Sbjct: 345 EIYEKFGKGDDARLEDITFESLKKCEYLKALLNEVLRLYPSVPQNFRVAQKDTSLPRGGG 404
Query: 428 ------TFIKKGSRVTYHPYAMGRMENIWGPDCLEFKPERWLKDGVFVPKCPFKYPVFQA 481
FI KG VTY YAM R E +G D F+PERW + K + + F
Sbjct: 405 PNRDQPIFIAKGQTVTYTVYAMHRDEQFYGKDSEVFRPERWFEPE--TRKLGWAFLPFNG 462
Query: 482 GSRVCLGKELAIVEMKSVVASLVKRF 507
G R+CLG++ A+ E V+A L + F
Sbjct: 463 GPRICLGQQFALTEASYVIARLAQLF 488
>CP46_MOUSE (Q9WVK8) Cytochrome p450 46A1 (EC 1.14.-.-) (Cholesterol
24-hydroxylase)
Length = 500
Score = 142 bits (357), Expect = 3e-33
Identities = 114/418 (27%), Positives = 218/418 (51%), Gaps = 34/418 (8%)
Query: 102 PTGTIHVHVLGNTITSNPENVE-YILKTNFNNYPKG-KQFSTILGD-LLGRGIFN-VDGH 157
P ++V + I ++PE+V+ +++ T +N K + T+ G+ L G+G+ + D
Sbjct: 73 PVVRVNVFYKTSVIVTSPESVKKFLMSTKYNKDSKMYRALQTVFGERLFGQGLVSECDYG 132
Query: 158 SWKFQRKMASLELGSVVIRSYAMELVIEEIKTRLLPLIASVAEKKTASKADNTSEDVLLD 217
W QRK+ L + S ME E+ + +L+ ++ + A+ +T +
Sbjct: 133 RWYKQRKVMDLAFSRSSLVSL-METFNEKAE-QLVEILEAKADGQTP-----------VS 179
Query: 218 MQDILRRFSFDNICKFSFGLDPCCLVPSL-PVSNLANAFDLSSTLSAQRALTASPLIWKM 276
MQD+L + D + K +FG++ L+ + P+S + +SA R A + K
Sbjct: 180 MQDMLTCATIDILAKAAFGMETSMLLGAQKPLSQAVKV--MLEGISASRNTLAKFMPGKR 237
Query: 277 KRFFNIGSEKKLKEAIKIVNDLANEMIKQRRE-IENGVESRKDLLSRFMGALN-SHDDEY 334
K+ ++++E+I+++ + + +++RRE ++ G + D+L++ + A + DDE
Sbjct: 238 KQL------REIRESIRLLRQVGKDWVQRRREALKRGEDMPADILTQILKAEEGAQDDEV 291
Query: 335 LRDIVVSFLLAGRDTVASALTGFFILLSKNPKVEEKIRVELDRVMNPNQECATFEQTREM 394
L D V+F +AG +T A+ L + LS+ P++ +++ E+D V+ + +E +
Sbjct: 292 LLDNFVTFFIAGHETSANHLAFTVMELSRQPEIVARLQAEVDEVVGSKRHL-DYEDLGRL 350
Query: 395 HYLNGAIHESMRLFPPVQFDSKFALEDDVLPDGTFIKKGSRVTYHPYAMGRMENIWGPDC 454
YL+ + ES+RL+PP + LE++ L DG + + + + Y MGRM+ + D
Sbjct: 351 QYLSQVLKESLRLYPPAWGTFRL-LEEETLIDGVRVPGNTPLLFSTYVMGRMDTYF-EDP 408
Query: 455 LEFKPERWLKDGVFVPKCPFKYPVFQAGSRVCLGKELAIVEMKSVVASLVKRFDVRVV 512
L F P+R+ G PK F Y F G R C+G++ A +E+K V+A L++R + R+V
Sbjct: 409 LTFNPDRF---GPGAPKPRFTYFPFSLGHRSCIGQQFAQMEVKVVMAKLLQRIEFRLV 463
>CP46_HUMAN (Q9Y6A2) Cytochrome p450 46A1 (EC 1.14.-.-) (Cholesterol
24-hydroxylase)
Length = 500
Score = 139 bits (350), Expect = 2e-32
Identities = 114/417 (27%), Positives = 217/417 (51%), Gaps = 32/417 (7%)
Query: 102 PTGTIHVHVLGNTITSNPENVE-YILKTNFNNYPKG-KQFSTILGD-LLGRGIFNVDGHS 158
P ++V + I ++PE+V+ +++ T +N K + T+ G+ L G+G+ + +
Sbjct: 73 PVVRVNVFHKTSVIVTSPESVKKFLMSTKYNKDSKMYRALQTVFGERLFGQGLVSECNYE 132
Query: 159 -WKFQRKMASLELGSVVIRSYAMELVIEEIKTRLLPLIASVAEKKTASKADNTSEDVLLD 217
W QR++ L + S ME E+ + +L+ ++ + A+ +T +
Sbjct: 133 RWHKQRRVIDLAFSRSSLVSL-METFNEKAE-QLVEILEAKADGQTP-----------VS 179
Query: 218 MQDILRRFSFDNICKFSFGLDPCCLVPSLPVSNLANAFDLSSTLSAQRALTASPLIWKMK 277
MQD+L + D + K +FG++ L+ + + A L ++A R A L K K
Sbjct: 180 MQDMLTYTAMDILAKAAFGMETSMLLGAQKPLSQAVKLMLEG-ITASRNTLAKFLPGKRK 238
Query: 278 RFFNIGSEKKLKEAIKIVNDLANEMIKQRRE-IENGVESRKDLLSRFMGALN-SHDDEYL 335
+ ++++E+I+ + + + +++RRE ++ G E D+L++ + A + DDE L
Sbjct: 239 QL------REVRESIRFLRQVGRDWVQRRREALKRGEEVPADILTQILKAEEGAQDDEGL 292
Query: 336 RDIVVSFLLAGRDTVASALTGFFILLSKNPKVEEKIRVELDRVMNPNQECATFEQTREMH 395
D V+F +AG +T A+ L + LS+ P++ +++ E+D V+ ++ FE +
Sbjct: 293 LDNFVTFFIAGHETSANHLAFTVMELSRQPEIVARLQAEVDEVIG-SKRYLDFEDLGRLQ 351
Query: 396 YLNGAIHESMRLFPPVQFDSKFALEDDVLPDGTFIKKGSRVTYHPYAMGRMENIWGPDCL 455
YL+ + ES+RL+PP + LE++ L DG + + + + Y MGRM+ + D L
Sbjct: 352 YLSQVLKESLRLYPPAWGTFRL-LEEETLIDGVRVPGNTPLLFSTYVMGRMDTYF-EDPL 409
Query: 456 EFKPERWLKDGVFVPKCPFKYPVFQAGSRVCLGKELAIVEMKSVVASLVKRFDVRVV 512
F P+R+ G PK F Y F G R C+G++ A +E+K V+A L++R + R+V
Sbjct: 410 TFNPDRF---GPGAPKPRFTYFPFSLGHRSCIGQQFAQMEVKVVMAKLLQRLEFRLV 463
>CP5W_CANAP (Q12573) Cytochrome P450 52E2 (EC 1.14.14.-) (CYPLIIE2)
Length = 519
Score = 134 bits (337), Expect = 6e-31
Identities = 115/455 (25%), Positives = 200/455 (43%), Gaps = 58/455 (12%)
Query: 89 NLVDYYTHLLQESPTGTIHVHVLGNTI--TSNPENVEYILKTNFNNYPKGKQFSTILGDL 146
+L++++TH +E T V G T PEN++ +L T+F +Y G +++ + G L
Sbjct: 67 DLLEWFTHRFEEFGRRTAFQSVAGQLWIGTIEPENIKTMLATSFKDYSLGFRYNAMYG-L 125
Query: 147 LGRGIFNVDGHSWKFQRKMASLELGSVVIRSYAMELVIEEIKTRLLPLIASVAEKKTASK 206
LG GIF + G WK R + + + +E ++T + +I +
Sbjct: 126 LGNGIFTLSGDGWKNSRALLRPQFSREQVSH------LESMRTHINMMINN--------- 170
Query: 207 ADNTSEDVLLDMQDILRRFSFDNICKFSFG-----LDPCCLVPSLPV-------SNLANA 254
+ ++D Q + + D +F FG LDP LP A A
Sbjct: 171 --HFKGGQVVDAQVLYHNLTIDTATEFLFGESTNTLDPALAQQGLPGPKGLVTGEQFAEA 228
Query: 255 FDLSSTLSAQRALTASP--LIWKMKRFFNIGSEKKLKEAIKIVNDLANEMIKQR--REIE 310
F + L + R + + L+W K + + K+ ++ + + + +E
Sbjct: 229 FTSALELLSVRVMAGAAWFLVWTPKFW----------RSCKVCHNFIDYFVYKALATPME 278
Query: 311 NGVESRKDLLSRFMGALNSHDDEYLRDIVVSFLLAGRDTVASALTGFFILLSKNPKVEEK 370
G ++ + + R + S D +RD ++ LLAGRDT A+ L+ L P+V ++
Sbjct: 279 KGQDADRYVFIRELTKETS-DPRVIRDQALNILLAGRDTTAALLSFTTYYLGAYPEVYDE 337
Query: 371 IR-VELDRVMNPNQECATFEQTREMHYLNGAIHESMRLFPPVQFDSKFALEDDVLPDG-- 427
+R + + + E TFEQ ++ L I E +RL P V + + A+ D P G
Sbjct: 338 LREAVIADFGSADAEPPTFEQLKQCKVLQNVIREVLRLHPNVPLNFREAIADTTFPTGGG 397
Query: 428 ------TFIKKGSRVTYHPYAMGRMENIWGPDCLEFKPERWLKDGVFVPKCPFKYPVFQA 481
F+ KG +V Y Y M R IWGPD F+P+RW + + + Y F
Sbjct: 398 PNGDQPIFVPKGQKVFYATYVMQRNAGIWGPDSTSFRPDRWNEPREALAS-GWDYIPFNG 456
Query: 482 GSRVCLGKELAIVEMKSVVASLVKRFD-VRVVGPN 515
G R+CLG++ A+ E + + + F + V+ P+
Sbjct: 457 GPRICLGQQFALTEASYTLVRICQEFSRIEVLHPD 491
>CP5I_CANMA (Q12586) Cytochrome P450 52A9 (EC 1.14.14.-) (CYPLIIA9)
(Alkane-inducible P450-ALK5-A)
Length = 521
Score = 133 bits (334), Expect = 1e-30
Identities = 114/454 (25%), Positives = 199/454 (43%), Gaps = 65/454 (14%)
Query: 115 ITSNPENVEYILKTNFNNYPKGKQFSTILGDLLGRGIFNVDGHSWKFQRKMASLELGSVV 174
+T +PEN++ IL T F ++ GK+ LLG GIF +DG WK R M +
Sbjct: 100 VTKDPENIKAILATQFEDFSLGKRLD-FFKPLLGYGIFTLDGEGWKHSRAMLRPQ----- 153
Query: 175 IRSYAMELV--IEEIKTRLLPLIASVAEKKTASKADNTSEDVLLDMQDILRRFSFDNICK 232
+A E V ++ I+ L + + K D+Q++ RF+ D+ +
Sbjct: 154 ---FAREQVGHVKLIEPHFQSLKKHIIKNKGQ----------FFDIQELFFRFTVDSATE 200
Query: 233 FSFGLDPCCLVPSLPVS---------------NLANAFDLSSTLSAQRALTASPLIWKMK 277
F FG V SL N A AF+ + RA+ ++
Sbjct: 201 FLFGES----VESLKDESIGYDQQDFDFDGRKNFAEAFNKAQEYLGTRAI--------LQ 248
Query: 278 RFFNIGSEKKLKEAIKIVNDLANEMIKQRREIE-NGVESRKDLLSRFMGALNSHDDEYLR 336
F+ + + K+++ V+ + +++ + +E + + + D + LR
Sbjct: 249 LFYWLVNGADFKKSVAEVHKFTDYYVQKALDATPEELEKHSGYIFLYELVQQTRDPKVLR 308
Query: 337 DIVVSFLLAGRDTVASALTGFFILLSKNPKVEEKIRVELDRVMNPNQECA----TFEQTR 392
D ++ LLAGRDT A L+ L++NP+V ++R E+ +++ +FE +
Sbjct: 309 DQSLNILLAGRDTTAGLLSFALFELARNPEVWSRLREEIGDKFGLDEDATIEGISFESLK 368
Query: 393 EMHYLNGAIHESMRLFPPVQFDSKFALEDDVLP--------DGTFIKKGSRVTYHPYAMG 444
+ YL ++E +R++P V + + A + LP D FIKKG+ V+Y +
Sbjct: 369 QCEYLKAVVNECLRMYPSVPRNFRIATKHTTLPRGGGPDGKDPIFIKKGAVVSYGINSTH 428
Query: 445 RMENIWGPDCLEFKPERWLKDGVFVPKCPFKYPVFQAGSRVCLGKELAIVEMKSVVASLV 504
+GPD F P+RW K K + + F G R+CLG++ A+ E V+ ++
Sbjct: 429 LDPMYYGPDARLFNPDRWSKPE--TKKLGWAFLPFNGGPRICLGQQFALTEASYVLVRMI 486
Query: 505 KRFDVRVVGPN--QEPQFAPGLTASFRGGLPVKI 536
+ F + PN P+ LT S G +K+
Sbjct: 487 QNFKELELTPNTVYPPRRLTNLTMSLYDGAYIKV 520
>CP5V_CANAP (P43083) Cytochrome P450 52E1 (EC 1.14.14.-) (CYPLIIE1)
Length = 519
Score = 132 bits (331), Expect = 3e-30
Identities = 113/446 (25%), Positives = 196/446 (43%), Gaps = 40/446 (8%)
Query: 89 NLVDYYTHLLQESPTGTIHVHVLGNT--ITSNPENVEYILKTNFNNYPKGKQFSTILGDL 146
NL++Y + + + T + G +T PEN++ +L T+F +Y G ++ + G L
Sbjct: 67 NLLEYISIRIADMKVRTGFQTLAGQRWLVTLEPENIKTVLATSFKDYSLGFRYDIMYG-L 125
Query: 147 LGRGIFNVDGHSWKFQRKMASLELGSVVIRSYAMELVIEEIKTRLLPLIASVAEKKTASK 206
LG GIF + G WK R + + + +E ++T + +I +
Sbjct: 126 LGNGIFTLSGDGWKHSRALLRPQFSREQVSH------LESMRTHINLMINN--------- 170
Query: 207 ADNTSEDVLLDMQDILRRFSFDNICKFSFGLDPCCLVPSLPVSNLANAFDLSSTLSAQRA 266
+ ++D Q + + D +F FG L P L L L + A
Sbjct: 171 --HFKGGQVVDAQALYHNLTIDTATEFLFGESTNTLDPDLAQQGLPGPKGLVTGEQFAEA 228
Query: 267 LTASPLIWKMK-----RFFNIGSEKKLKEAIKIVNDLANEMIKQR--REIENGVESRKDL 319
T++ I ++ +F I + K + K+ ++ + + + +E E+ + +
Sbjct: 229 FTSALEILSVRVIVGAAWFLIWTPKFWRSC-KVCHNFIDYFVYKALATPMEKDQEADRYV 287
Query: 320 LSRFMGALNSHDDEYLRDIVVSFLLAGRDTVASALTGFFILLSKNPKVEEKIR-VELDRV 378
R + S D +RD ++ LLAGRDT A L+ L P+V ++R L
Sbjct: 288 FIRELTKETS-DPRVIRDQALNILLAGRDTTAGLLSFITYYLGAYPEVYAELREAVLSEF 346
Query: 379 MNPNQECATFEQTREMHYLNGAIHESMRLFPPVQFDSKFALEDDVLPDG--------TFI 430
+ + E TFEQ ++ L I E +RL P V + + A+ D LP G F+
Sbjct: 347 GSTDVETPTFEQLKQCKVLQNVIREVLRLHPNVPLNFRQAIVDTKLPTGGGPNGDQPVFV 406
Query: 431 KKGSRVTYHPYAMGRMENIWGPDCLEFKPERWLKDGVFVPKCPFKYPVFQAGSRVCLGKE 490
KG V Y Y+M R +IWGPD F+P+RW + + + Y F G R+CLG++
Sbjct: 407 PKGQNVFYSTYSMQRRTDIWGPDATTFRPDRWNEPREALAS-GWDYIPFNGGPRICLGQQ 465
Query: 491 LAIVEMKSVVASLVKRFD-VRVVGPN 515
A+ E + + + F + V+ P+
Sbjct: 466 FALTEASYTIVRICQEFSRIEVLHPD 491
Database: sprot
Posted date: Nov 25, 2004 10:54 AM
Number of letters in database: 59,974,054
Number of sequences in database: 164,201
Lambda K H
0.323 0.138 0.410
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 61,271,204
Number of Sequences: 164201
Number of extensions: 2557206
Number of successful extensions: 8200
Number of sequences better than 10.0: 681
Number of HSP's better than 10.0 without gapping: 436
Number of HSP's successfully gapped in prelim test: 245
Number of HSP's that attempted gapping in prelim test: 6656
Number of HSP's gapped (non-prelim): 800
length of query: 540
length of database: 59,974,054
effective HSP length: 115
effective length of query: 425
effective length of database: 41,090,939
effective search space: 17463649075
effective search space used: 17463649075
T: 11
A: 40
X1: 16 ( 7.5 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (22.0 bits)
S2: 68 (30.8 bits)
Medicago: description of AC127021.9