BLAST2 result
BLASTP 2.2.2 [Dec-14-2001]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= AC126786.6 - phase: 0
(228 letters)
Database: sprot
164,201 sequences; 59,974,054 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
FKB1_ARATH (Q9LM71) Probable FKBP-type peptidyl-prolyl cis-trans... 280 2e-75
FK14_HUMAN (Q9NWM8) FK506 binding protein 14 precursor (EC 5.2.1... 51 3e-06
FK14_MOUSE (P59024) FK506 binding protein 14 precursor (EC 5.2.1... 49 8e-06
FKB9_MOUSE (Q9Z247) FK506 binding protein 9 precursor (EC 5.2.1.... 45 1e-04
FKB4_SPOFR (Q26486) 46 kDa FK506-binding nuclear protein (EC 5.2... 45 1e-04
FKB9_HUMAN (O95302) FK506 binding protein 9 (EC 5.2.1.8) (Peptid... 44 2e-04
FKB3_ARATH (Q9SCY2) FKBP-type peptidyl-prolyl cis-trans isomeras... 44 2e-04
FKBA_ECOLI (P45523) FKBP-type peptidyl-prolyl cis-trans isomeras... 43 5e-04
FKBA_ECOL6 (P65764) FKBP-type peptidyl-prolyl cis-trans isomeras... 43 5e-04
FKBA_ECO57 (P65765) FKBP-type peptidyl-prolyl cis-trans isomeras... 43 5e-04
FKB4_DROME (P54397) 39 kDa FK506-binding nuclear protein (EC 5.2... 42 0.001
FKBP_NEIMA (P56989) FK506-binding protein (Peptidyl-prolyl cis-t... 42 0.002
FKBP_NEIMB (P25138) FK506-binding protein (Peptidyl-prolyl cis-t... 40 0.004
FKB2_NEUCR (O60046) FK506-binding protein 2 precursor (EC 5.2.1.... 40 0.006
FKBA_BUCAP (Q8K943) FKBP-type peptidyl-prolyl cis-trans isomeras... 39 0.008
FKB2_MOUSE (P45878) FK506-binding protein 2 precursor (EC 5.2.1.... 39 0.008
FKB2_HUMAN (P26885) FK506-binding protein 2 precursor (EC 5.2.1.... 39 0.008
FKB7_MOUSE (O54998) FK506-binding protein 7 precursor (EC 5.2.1.... 38 0.017
FKBP_CORGL (P42458) Probable FK506-binding protein (Peptidyl-pro... 38 0.023
FKB3_YEAST (P38911) FK506-binding nuclear protein (EC 5.2.1.8) (... 37 0.030
>FKB1_ARATH (Q9LM71) Probable FKBP-type peptidyl-prolyl cis-trans
isomerase 1, chloroplast precursor (EC 5.2.1.8) (PPIase)
(Rotamase)
Length = 232
Score = 280 bits (717), Expect = 2e-75
Identities = 138/190 (72%), Positives = 159/190 (83%), Gaps = 3/190 (1%)
Query: 39 VVALS---QSRRSTAILISSLPFTFVFLSPPPPAEARERRKKKNIPIDDYITSPDGLKYY 95
VVA S R ++ IL+SS+P T F+ P +EARERR +K IP+++Y T P+GLK+Y
Sbjct: 36 VVAFSVPISRRDASIILLSSIPLTSFFVLTPSSSEARERRSRKVIPLEEYSTGPEGLKFY 95
Query: 96 DFLEGKGPIAEKGSTVQVHFDCLYRGITAVSSRESKLLAGNRVIAQPYEFKVGAPPGKER 155
D EGKGP+A +GST QVHFDC YR ITA+S+RESKLLAGNR IAQPYEFKVG+ PGKER
Sbjct: 96 DIEEGKGPVATEGSTAQVHFDCRYRSITAISTRESKLLAGNRSIAQPYEFKVGSTPGKER 155
Query: 156 KREFVDNPNGLFSAQAAPKPPQAMYTIVEGMRVGGKRTVIVPPEKGYGKKGMNEIPPGAT 215
KREFVDNPNGLFSAQAAPKPP AMY I EGM+VGGKRTVIVPPE GYG+KGMNEIPPGAT
Sbjct: 156 KREFVDNPNGLFSAQAAPKPPPAMYFITEGMKVGGKRTVIVPPEAGYGQKGMNEIPPGAT 215
Query: 216 FELNIELLQL 225
FELNIELL++
Sbjct: 216 FELNIELLRV 225
>FK14_HUMAN (Q9NWM8) FK506 binding protein 14 precursor (EC 5.2.1.8)
(Peptidyl-prolyl cis-trans isomerase) (PPIase)
(Rotamase) (22 kDa FK506-binding protein) (FKBP-22)
(UNQ322/PRO381)
Length = 211
Score = 50.8 bits (120), Expect = 3e-06
Identities = 22/43 (51%), Positives = 32/43 (74%)
Query: 183 VEGMRVGGKRTVIVPPEKGYGKKGMNEIPPGATFELNIELLQL 225
++GM VG KR +I+PP GYGK+G +IPP +T NI+LL++
Sbjct: 92 LKGMCVGEKRKLIIPPALGYGKEGKGKIPPESTLIFNIDLLEI 134
>FK14_MOUSE (P59024) FK506 binding protein 14 precursor (EC 5.2.1.8)
(Peptidyl-prolyl cis-trans isomerase) (PPIase)
(Rotamase)
Length = 211
Score = 49.3 bits (116), Expect = 8e-06
Identities = 22/43 (51%), Positives = 31/43 (71%)
Query: 183 VEGMRVGGKRTVIVPPEKGYGKKGMNEIPPGATFELNIELLQL 225
++GM VG KR + VPP GYGK+G +IPP +T NI+LL++
Sbjct: 92 LKGMCVGEKRKLTVPPALGYGKEGKGKIPPESTLIFNIDLLEI 134
>FKB9_MOUSE (Q9Z247) FK506 binding protein 9 precursor (EC 5.2.1.8)
(Peptidyl-prolyl cis-trans isomerase) (PPIase)
(Rotamase) (FKBP65RS)
Length = 570
Score = 45.4 bits (106), Expect = 1e-04
Identities = 23/43 (53%), Positives = 30/43 (69%), Gaps = 1/43 (2%)
Query: 186 MRVGGKRTVIVPPEKGYGKKGMN-EIPPGATFELNIELLQLAS 227
M VG KRTVI+PP GYG+ G++ E+P A +IELL+L S
Sbjct: 436 MCVGEKRTVIIPPHLGYGEAGVDGEVPGSAVLVFDIELLELVS 478
Score = 38.5 bits (88), Expect = 0.013
Identities = 15/39 (38%), Positives = 24/39 (61%)
Query: 185 GMRVGGKRTVIVPPEKGYGKKGMNEIPPGATFELNIELL 223
G+ +G +R ++VPP GYG+KG IP A +I ++
Sbjct: 324 GVCIGERRRIVVPPHLGYGEKGRGSIPGSAVLVFDIHVI 362
Score = 32.7 bits (73), Expect = 0.73
Identities = 18/42 (42%), Positives = 25/42 (58%), Gaps = 1/42 (2%)
Query: 185 GMRVGGKRTVIVPPEKGYGKKG-MNEIPPGATFELNIELLQL 225
GM VG KR + VPP YG++G +IP A+ ++ LL L
Sbjct: 212 GMCVGEKRIITVPPFLAYGEEGDGKDIPGQASLVFDVALLDL 253
Score = 31.2 bits (69), Expect = 2.1
Identities = 14/42 (33%), Positives = 24/42 (56%), Gaps = 1/42 (2%)
Query: 185 GMRVGGKRTVIVPPEKGYGKKGMN-EIPPGATFELNIELLQL 225
GM V +R V +PP YG +G++ IPP + ++ L+ +
Sbjct: 100 GMCVNERRLVTIPPNLAYGSEGVSGVIPPNSVLHFDVLLVDI 141
>FKB4_SPOFR (Q26486) 46 kDa FK506-binding nuclear protein (EC
5.2.1.8) (Peptidyl-prolyl cis-trans isomerase) (PPIase)
(Rotamase)
Length = 412
Score = 45.4 bits (106), Expect = 1e-04
Identities = 36/151 (23%), Positives = 64/151 (41%), Gaps = 40/151 (26%)
Query: 73 ERRKKKNIPIDDYITSPDGLKYYDFLEGKGPIAEKGSTVQVHFDCLYRGITAVSSRESKL 132
E+++KK I G+ D G GP+A+ G V V+++ + ++
Sbjct: 297 EKKEKKQIA--------GGVSIEDLKVGSGPVAKAGKVVMVYYEGRLK--------QNNK 340
Query: 133 LAGNRVIAQPYEFKVGAPPGKERKREFVDNPNGLFSAQAAPKPPQAMYTIVEGMRVGGKR 192
+ N V ++F++G+ +E + + + GM+VGGKR
Sbjct: 341 MFDNCVKGPGFKFRLGS-------KEVISGWD----------------VGIAGMKVGGKR 377
Query: 193 TVIVPPEKGYGKKGMNE-IPPGATFELNIEL 222
++ PP YG KG IPP +T ++L
Sbjct: 378 KIVCPPAMAYGAKGSPPVIPPNSTLVFEVDL 408
>FKB9_HUMAN (O95302) FK506 binding protein 9 (EC 5.2.1.8)
(Peptidyl-prolyl cis-trans isomerase) (PPIase)
(Rotamase) (Fragment)
Length = 517
Score = 44.3 bits (103), Expect = 2e-04
Identities = 22/43 (51%), Positives = 30/43 (69%), Gaps = 1/43 (2%)
Query: 186 MRVGGKRTVIVPPEKGYGKKGMN-EIPPGATFELNIELLQLAS 227
M VG KRTVI+PP GYG+ G++ E+P A +IELL+L +
Sbjct: 383 MCVGEKRTVIIPPHLGYGEAGVDGEVPGSAVLVFDIELLELVA 425
Score = 38.1 bits (87), Expect = 0.017
Identities = 15/39 (38%), Positives = 24/39 (61%)
Query: 185 GMRVGGKRTVIVPPEKGYGKKGMNEIPPGATFELNIELL 223
G+ +G KR ++VPP GYG++G IP A +I ++
Sbjct: 271 GVCIGEKRRIVVPPHLGYGEEGRGNIPGSAVLVFDIHVI 309
Score = 31.6 bits (70), Expect = 1.6
Identities = 17/42 (40%), Positives = 24/42 (56%), Gaps = 1/42 (2%)
Query: 185 GMRVGGKRTVIVPPEKGYGKKG-MNEIPPGATFELNIELLQL 225
GM VG KR + +PP YG+ G +IP A+ ++ LL L
Sbjct: 159 GMCVGEKRIITIPPFLAYGEDGDGKDIPGQASLVFDVALLDL 200
Score = 30.8 bits (68), Expect = 2.8
Identities = 14/42 (33%), Positives = 25/42 (59%), Gaps = 1/42 (2%)
Query: 185 GMRVGGKRTVIVPPEKGYGKKGMN-EIPPGATFELNIELLQL 225
GM V +R V +PP+ YG +G++ IPP + ++ L+ +
Sbjct: 47 GMCVNERRFVKIPPKLAYGNEGVSGVIPPNSVLHFDVLLMDI 88
>FKB3_ARATH (Q9SCY2) FKBP-type peptidyl-prolyl cis-trans isomerase
3, chloroplast precursor (EC 5.2.1.8) (PPIase)
(Rotamase) (AtFKBP13) (FK506 binding protein 1)
Length = 208
Score = 44.3 bits (103), Expect = 2e-04
Identities = 38/147 (25%), Positives = 62/147 (41%), Gaps = 33/147 (22%)
Query: 84 DYITSPDGLKYYDFLEGKGPIAEKGSTVQVHFDCLYRGITAVSSRES-KLLAGNRVIAQP 142
++ SP GL + D + G GP A KG ++ H+ V E+ K+ + +P
Sbjct: 85 EFSVSPSGLAFCDKVVGYGPEAVKGQLIKAHY---------VGKLENGKVFDSSYNRGKP 135
Query: 143 YEFKVGAPPGKERKREFVDNPNGLFSAQAAPKPPQAMYTIVEGMRVGGKRTVIVPPEKGY 202
F++G + + + +G+ PP M GGKRT+ +PPE Y
Sbjct: 136 LTFRIGVGEVIKGWDQGILGSDGI--------PP---------MLTGGKRTLRIPPELAY 178
Query: 203 GKKGMN------EIPPGATFELNIELL 223
G +G IPP + +IE +
Sbjct: 179 GDRGAGCKGGSCLIPPASVLLFDIEYI 205
>FKBA_ECOLI (P45523) FKBP-type peptidyl-prolyl cis-trans isomerase
fkpA precursor (EC 5.2.1.8) (PPIase) (Rotamase)
Length = 270
Score = 43.1 bits (100), Expect = 5e-04
Identities = 17/43 (39%), Positives = 29/43 (66%)
Query: 183 VEGMRVGGKRTVIVPPEKGYGKKGMNEIPPGATFELNIELLQL 225
++ ++ GGK +++PPE YGK G+ IPP +T ++ELL +
Sbjct: 206 LKNIKKGGKIKLVIPPELAYGKAGVPGIPPNSTLVFDVELLDV 248
>FKBA_ECOL6 (P65764) FKBP-type peptidyl-prolyl cis-trans isomerase
fkpA precursor (EC 5.2.1.8) (PPIase) (Rotamase)
Length = 270
Score = 43.1 bits (100), Expect = 5e-04
Identities = 17/43 (39%), Positives = 29/43 (66%)
Query: 183 VEGMRVGGKRTVIVPPEKGYGKKGMNEIPPGATFELNIELLQL 225
++ ++ GGK +++PPE YGK G+ IPP +T ++ELL +
Sbjct: 206 LKNIKKGGKIKLVIPPELAYGKAGVPGIPPNSTLVFDVELLDV 248
>FKBA_ECO57 (P65765) FKBP-type peptidyl-prolyl cis-trans isomerase
fkpA precursor (EC 5.2.1.8) (PPIase) (Rotamase)
Length = 270
Score = 43.1 bits (100), Expect = 5e-04
Identities = 17/43 (39%), Positives = 29/43 (66%)
Query: 183 VEGMRVGGKRTVIVPPEKGYGKKGMNEIPPGATFELNIELLQL 225
++ ++ GGK +++PPE YGK G+ IPP +T ++ELL +
Sbjct: 206 LKNIKKGGKIKLVIPPELAYGKAGVPGIPPNSTLVFDVELLDV 248
>FKB4_DROME (P54397) 39 kDa FK506-binding nuclear protein (EC
5.2.1.8) (Peptidyl-prolyl cis-trans isomerase) (PPIase)
(Rotamase)
Length = 357
Score = 42.0 bits (97), Expect = 0.001
Identities = 43/160 (26%), Positives = 66/160 (40%), Gaps = 38/160 (23%)
Query: 70 EARERRKKKNIPIDDYITSPD------GLKYYDFLEGKGPIAEKGSTVQVHFDCLYRGIT 123
EA++ + K P S D G+K D + GKG A++G V V++ +
Sbjct: 225 EAKKEQPKAKEPAKQQPASKDPRTITGGVKIVDQVVGKGEEAKQGKRVSVYY---IGRLQ 281
Query: 124 AVSSRESKLLAGNRVIAQPYEFKVGAPPGKERKREFVDNPNGLFSAQAAPKPPQAMYTIV 183
+ + LL G +P++F +G G+ K V V
Sbjct: 282 SNNKTFDSLLKG-----KPFKFALGG--GEVIKGWDVG---------------------V 313
Query: 184 EGMRVGGKRTVIVPPEKGYGKKGM-NEIPPGATFELNIEL 222
GM+VGGKR + PP YG +G +I P +T +EL
Sbjct: 314 AGMKVGGKRVITCPPHMAYGARGAPPKIGPNSTLVFEVEL 353
>FKBP_NEIMA (P56989) FK506-binding protein (Peptidyl-prolyl
cis-trans isomerase) (PPIase) (EC 5.2.1.8) (Rotamase)
Length = 109
Score = 41.6 bits (96), Expect = 0.002
Identities = 20/42 (47%), Positives = 27/42 (63%), Gaps = 1/42 (2%)
Query: 185 GMRVGGKRTVIVPPEKGYGKKGM-NEIPPGATFELNIELLQL 225
GM+ GGKR + +P E GYG +G IPP AT +ELL++
Sbjct: 66 GMKEGGKRKLTIPSEMGYGARGAGGVIPPHATLIFEVELLKV 107
>FKBP_NEIMB (P25138) FK506-binding protein (Peptidyl-prolyl
cis-trans isomerase) (PPIase) (EC 5.2.1.8) (Rotamase)
Length = 109
Score = 40.4 bits (93), Expect = 0.004
Identities = 20/42 (47%), Positives = 26/42 (61%), Gaps = 1/42 (2%)
Query: 185 GMRVGGKRTVIVPPEKGYGKKGM-NEIPPGATFELNIELLQL 225
GM+ GGKR + +P E GYG G IPP AT +ELL++
Sbjct: 66 GMKEGGKRKLTIPSEMGYGAHGAGGVIPPHATLIFEVELLKV 107
>FKB2_NEUCR (O60046) FK506-binding protein 2 precursor (EC 5.2.1.8)
(Peptidyl-prolyl cis-trans isomerase) (PPIase)
(Rotamase) (FKBP-21) (NcFKBP22)
Length = 217
Score = 39.7 bits (91), Expect = 0.006
Identities = 17/38 (44%), Positives = 24/38 (62%)
Query: 186 MRVGGKRTVIVPPEKGYGKKGMNEIPPGATFELNIELL 223
M +G KRT+ VPP GYG++ + IP G+T EL+
Sbjct: 89 MCIGEKRTLTVPPSYGYGQRSIGPIPAGSTLIFETELI 126
>FKBA_BUCAP (Q8K943) FKBP-type peptidyl-prolyl cis-trans isomerase
fkpA (EC 5.2.1.8) (PPIase) (Rotamase)
Length = 252
Score = 39.3 bits (90), Expect = 0.008
Identities = 17/40 (42%), Positives = 25/40 (62%)
Query: 186 MRVGGKRTVIVPPEKGYGKKGMNEIPPGATFELNIELLQL 225
++ GGK +I+PP GYG +NEIP + +IELL +
Sbjct: 210 IKKGGKIKLIIPPNLGYGSNRINEIPANSILIFDIELLDI 249
>FKB2_MOUSE (P45878) FK506-binding protein 2 precursor (EC 5.2.1.8)
(Peptidyl-prolyl cis-trans isomerase) (PPIase)
(Rotamase) (13 kDa FKBP) (FKBP-13)
Length = 140
Score = 39.3 bits (90), Expect = 0.008
Identities = 19/42 (45%), Positives = 28/42 (66%), Gaps = 1/42 (2%)
Query: 185 GMRVGGKRTVIVPPEKGYGKKGM-NEIPPGATFELNIELLQL 225
GM G KR +++P E GYG++G +IP GAT +ELL++
Sbjct: 93 GMCEGEKRKLVIPSELGYGERGAPPKIPGGATLVFEVELLKI 134
>FKB2_HUMAN (P26885) FK506-binding protein 2 precursor (EC 5.2.1.8)
(Peptidyl-prolyl cis-trans isomerase) (PPIase)
(Rotamase) (13 kDa FKBP) (FKBP-13)
Length = 142
Score = 39.3 bits (90), Expect = 0.008
Identities = 19/42 (45%), Positives = 28/42 (66%), Gaps = 1/42 (2%)
Query: 185 GMRVGGKRTVIVPPEKGYGKKGM-NEIPPGATFELNIELLQL 225
GM G KR +++P E GYG++G +IP GAT +ELL++
Sbjct: 95 GMCEGEKRKLVIPSELGYGERGAPPKIPGGATLVFEVELLKI 136
>FKB7_MOUSE (O54998) FK506-binding protein 7 precursor (EC 5.2.1.8)
(Peptidyl-prolyl cis-trans isomerase) (PPIase)
(Rotamase) (FKBP-23)
Length = 218
Score = 38.1 bits (87), Expect = 0.017
Identities = 20/36 (55%), Positives = 22/36 (60%), Gaps = 2/36 (5%)
Query: 189 GGKRTVIVPPEKGYGKKGMNE--IPPGATFELNIEL 222
G KR VI+PP YGK+G E IPP AT IEL
Sbjct: 102 GEKRKVIIPPSFAYGKEGYAEGKIPPNATLMFEIEL 137
>FKBP_CORGL (P42458) Probable FK506-binding protein (Peptidyl-prolyl
cis-trans isomerase) (PPIase) (EC 5.2.1.8) (Rotamase)
Length = 118
Score = 37.7 bits (86), Expect = 0.023
Identities = 16/41 (39%), Positives = 24/41 (58%)
Query: 183 VEGMRVGGKRTVIVPPEKGYGKKGMNEIPPGATFELNIELL 223
+ GM+VGG+R + +PPE YG +G G T I+L+
Sbjct: 76 IPGMKVGGRRQLTIPPEAAYGPEGSGHPLSGRTLVFIIDLI 116
>FKB3_YEAST (P38911) FK506-binding nuclear protein (EC 5.2.1.8)
(Peptidyl-prolyl cis-trans isomerase) (PPIase) (Proline
rotamase) (Nucleolar proline isomerase) (FKBP-70)
Length = 411
Score = 37.4 bits (85), Expect = 0.030
Identities = 15/43 (34%), Positives = 26/43 (59%)
Query: 183 VEGMRVGGKRTVIVPPEKGYGKKGMNEIPPGATFELNIELLQL 225
V GM VGG+R +I+P YGK+ + IP + +++L+ +
Sbjct: 367 VAGMSVGGERRIIIPAPYAYGKQALPGIPANSELTFDVKLVSM 409
Database: sprot
Posted date: Nov 25, 2004 10:54 AM
Number of letters in database: 59,974,054
Number of sequences in database: 164,201
Lambda K H
0.317 0.136 0.398
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 28,991,008
Number of Sequences: 164201
Number of extensions: 1272131
Number of successful extensions: 3038
Number of sequences better than 10.0: 60
Number of HSP's better than 10.0 without gapping: 30
Number of HSP's successfully gapped in prelim test: 30
Number of HSP's that attempted gapping in prelim test: 2982
Number of HSP's gapped (non-prelim): 82
length of query: 228
length of database: 59,974,054
effective HSP length: 106
effective length of query: 122
effective length of database: 42,568,748
effective search space: 5193387256
effective search space used: 5193387256
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 64 (29.3 bits)
Medicago: description of AC126786.6