BLASTP 2.2.2 [Dec-14-2001]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= AC126019.10 + phase: 0 
         (435 letters)

Database: sprot 
           164,201 sequences; 59,974,054 total letters

Searching..................................................done

                                                                   Score     E
Sequences producing significant alignments:                        (bits)  Value

THIK_RAT (P07871) 3-ketoacyl-CoA thiolase B, peroxisomal precurs...   441  e-123
THIJ_RAT (P21775) 3-ketoacyl-CoA thiolase A, peroxisomal precurs...   436  e-122
THIK_HUMAN (P09110) 3-ketoacyl-CoA thiolase, peroxisomal precurs...   436  e-122
THIK_YARLI (Q05493) 3-ketoacyl-CoA thiolase, peroxisomal precurs...   381  e-105
THIL_CANTR (P33291) 3-ketoacyl-CoA thiolase B, peroxisomal precu...   340  3e-93
THIK_CANTR (P33290) 3-ketoacyl-CoA thiolase A, peroxisomal precu...   338  2e-92
THIK_YEAST (P27796) 3-ketoacyl-CoA thiolase, peroxisomal precurs...   321  2e-87
THIL_CHRVO (Q9ZHI1) Acetyl-CoA acetyltransferase (EC 2.3.1.9) (A...   290  4e-78
THLA_CLOAB (P45359) Acetyl-CoA acetyltransferase (EC 2.3.1.9) (A...   278  2e-74
THIL_ALCEU (P14611) Acetyl-CoA acetyltransferase (EC 2.3.1.9) (A...   274  4e-73
THIL_ZOORA (P07097) Acetyl-CoA acetyltransferase (EC 2.3.1.9) (A...   272  1e-72
ATOB_ECOLI (P76461) Acetyl-CoA acetyltransferase (EC 2.3.1.9) (A...   269  9e-72
THIL_RHIME (P50174) Acetyl-CoA acetyltransferase (EC 2.3.1.9) (A...   268  2e-71
ATOB_HAEIN (P44873) Acetyl-CoA acetyltransferase (EC 2.3.1.9) (A...   265  2e-70
THIL_THIVI (P45363) Acetyl-CoA acetyltransferase (EC 2.3.1.9) (A...   265  2e-70
YQEF_ECOLI (Q46939) Probable acetyl-CoA acetyltransferase (EC 2....   256  8e-68
THIL_CHRVI (P45369) Acetyl-CoA acetyltransferase (EC 2.3.1.9) (A...   256  1e-67
THIL_PARDE (P54810) Acetyl-CoA acetyltransferase (EC 2.3.1.9) (A...   255  1e-67
THIK_PSEFR (P28790) 3-ketoacyl-CoA thiolase (EC 2.3.1.16) (Fatty...   253  7e-67
THIK_SALTY (Q9L6L6) 3-ketoacyl-CoA thiolase (EC 2.3.1.16) (Fatty...   250  4e-66

>THIK_RAT (P07871) 3-ketoacyl-CoA thiolase B, peroxisomal precursor
           (EC 2.3.1.16) (Beta-ketothiolase B) (Acetyl-CoA
           acyltransferase B) (Peroxisomal 3-oxoacyl-CoA thiolase
           B)
          Length = 424

 Score =  441 bits (1133), Expect = e-123
 Identities = 237/427 (55%), Positives = 313/427 (72%), Gaps = 7/427 (1%)

Query: 5   VERQRVLLQHLNPNSVTSSHHSTHLSASLCSAGQTGGSENDVVIVAAYRTAICKAKRGGF 64
           + R +V+L HL   S +SS     L A+ CSAG    S +DVV+V   RT I +A RGGF
Sbjct: 1   MHRLQVVLGHLAGRSESSSA----LQAAPCSAGFPQASASDVVVVHGRRTPIGRAGRGGF 56

Query: 65  KDTLPDDLLASVLKAVIEKTNVEPSEVGDIVVGTVLGPGSERAIECRMAAFYAGFPDTVP 124
           KDT PD+LL++VL AV++   ++P  +GDI VG VL PG+  A+  R+A F +G P+TVP
Sbjct: 57  KDTTPDELLSAVLTAVLQDVKLKPECLGDISVGNVLQPGAGAAM-ARIAQFLSGIPETVP 115

Query: 125 LRTVNRQCSSGLQAVADVAAYIKAGFYDIGIGAGLECMTQDTISGVRKTNPKVEIFAQAR 184
           L  VNRQCSSGLQAVA++A  I+ G YDIG+  G+E MT          + ++    +AR
Sbjct: 116 LSAVNRQCSSGLQAVANIAGGIRNGSYDIGMACGVESMTLSERGNPGNISSRLLENEKAR 175

Query: 185 DCLLSMGITSENVAQRYGVTRQEQDQAAVESHRRAAAATASGKFKDEIIPVSTKFVDPKT 244
           DCL+ MGITSENVA+R+G++RQ+QD  A+ S ++AA+A + G F+ EI+PV+T  +D K 
Sbjct: 176 DCLIPMGITSENVAERFGISRQKQDAFALASQQKAASAQSKGCFRAEIVPVTTTVLDDK- 234

Query: 245 GEEKQIIVSVDDGIRPNANLVDLAKLKPAFKKDGTTTAGNASQVSDGAAAVLLMKRSVAV 304
           G+ K I VS D+G+RP+  +  LAKLKPAFK  G+TTAGN+SQVSDGAAAVLL +RS A 
Sbjct: 235 GDRKTITVSQDEGVRPSTTMEGLAKLKPAFKDGGSTTAGNSSQVSDGAAAVLLARRSKAE 294

Query: 305 QKGLPILGIFRSFSAVGVDPAVMGVGPAFAIPAAVKSAGLELSNIDLYEINEAFASQFVY 364
           + GLPILG+ RS++ VGV P +MG+GPA+AIPAA++ AGL +++ID++EINEAFASQ +Y
Sbjct: 295 ELGLPILGVLRSYAVVGVPPDIMGIGPAYAIPAALQKAGLTVNDIDIFEINEAFASQALY 354

Query: 365 SCKKLGLDPTKVNVNGGAMAFGHPLGATGARCVATLLNEMKRRGKDCRFGVISMCIGSGM 424
             +KLG+   KVN  GGA+A GHPLG TGAR V TLLNE+KRRG+   +GV+SMCIG+GM
Sbjct: 355 CVEKLGIPAEKVNPLGGAIALGHPLGCTGARQVVTLLNELKRRGRRA-YGVVSMCIGTGM 413

Query: 425 GAAAVFE 431
           GAAAVFE
Sbjct: 414 GAAAVFE 420


>THIJ_RAT (P21775) 3-ketoacyl-CoA thiolase A, peroxisomal precursor
           (EC 2.3.1.16) (Beta-ketothiolase A) (Acetyl-CoA
           acyltransferase A) (Peroxisomal 3-oxoacyl-CoA thiolase
           A)
          Length = 434

 Score =  436 bits (1122), Expect = e-122
 Identities = 235/428 (54%), Positives = 312/428 (71%), Gaps = 7/428 (1%)

Query: 4   AVERQRVLLQHLNPNSVTSSHHSTHLSASLCSAGQTGGSENDVVIVAAYRTAICKAKRGG 63
           A+ R +V+L HL     +SS     L A+ CSA     S +DVV+V   RT I +A RGG
Sbjct: 10  AMHRLQVVLGHLAGRPESSSA----LQAAPCSATFPQASASDVVVVHGRRTPIGRAGRGG 65

Query: 64  FKDTLPDDLLASVLKAVIEKTNVEPSEVGDIVVGTVLGPGSERAIECRMAAFYAGFPDTV 123
           FKDT PD+LL++VL AV++   ++P  +GDI VG VL PG+  A+  R+A F +G P+TV
Sbjct: 66  FKDTTPDELLSAVLTAVLQDVKLKPECLGDISVGNVLEPGAG-AVMARIAQFLSGIPETV 124

Query: 124 PLRTVNRQCSSGLQAVADVAAYIKAGFYDIGIGAGLECMTQDTISGVRKTNPKVEIFAQA 183
           PL  VNRQCSSGLQAVA++A  I+ G YDIG+  G+E M+          + ++    +A
Sbjct: 125 PLSAVNRQCSSGLQAVANIAGGIRNGSYDIGMACGVESMSLSNRGNPGNISSRLLESDKA 184

Query: 184 RDCLLSMGITSENVAQRYGVTRQEQDQAAVESHRRAAAATASGKFKDEIIPVSTKFVDPK 243
           RDCL+ MGITSENVA+R+G++RQ+QD  A+ S ++AA+A + G F+ EI+PV+T  +D K
Sbjct: 185 RDCLIPMGITSENVAERFGISRQKQDAFALASQQKAASAQSKGCFRAEIVPVTTTVLDDK 244

Query: 244 TGEEKQIIVSVDDGIRPNANLVDLAKLKPAFKKDGTTTAGNASQVSDGAAAVLLMKRSVA 303
            G+ K I VS D+G+RP+  +  LAKLKPAFK  G+TTAGN+SQVSDGAAAVLL +RS A
Sbjct: 245 -GDRKTITVSQDEGVRPSTTMEGLAKLKPAFKDGGSTTAGNSSQVSDGAAAVLLARRSKA 303

Query: 304 VQKGLPILGIFRSFSAVGVDPAVMGVGPAFAIPAAVKSAGLELSNIDLYEINEAFASQFV 363
            + GLPILG+ RS++ VGV P +MG+GPA+AIPAA++ AGL +++ID++EINEAFASQ +
Sbjct: 304 EELGLPILGVLRSYAVVGVPPDIMGIGPAYAIPAALQKAGLTVNDIDIFEINEAFASQAL 363

Query: 364 YSCKKLGLDPTKVNVNGGAMAFGHPLGATGARCVATLLNEMKRRGKDCRFGVISMCIGSG 423
           Y  +KLG+   KVN  GGA+A GHPLG TGAR V TLLNE+KRRG+   +GV+SMCIG+G
Sbjct: 364 YCVEKLGIPAEKVNPLGGAIALGHPLGCTGARQVVTLLNELKRRGRRA-YGVVSMCIGTG 422

Query: 424 MGAAAVFE 431
           MGAAAVFE
Sbjct: 423 MGAAAVFE 430


>THIK_HUMAN (P09110) 3-ketoacyl-CoA thiolase, peroxisomal precursor
           (EC 2.3.1.16) (Beta-ketothiolase) (Acetyl-CoA
           acyltransferase) (Peroxisomal 3-oxoacyl-CoA thiolase)
          Length = 424

 Score =  436 bits (1121), Expect = e-122
 Identities = 228/401 (56%), Positives = 297/401 (73%), Gaps = 3/401 (0%)

Query: 31  ASLCSAGQTGGSENDVVIVAAYRTAICKAKRGGFKDTLPDDLLASVLKAVIEKTNVEPSE 90
           A+ C +G    S  DVV+V   RTAIC+A RGGFKDT PD+LL++V+ AV++  N+ P +
Sbjct: 23  AAPCLSGAPQASAADVVVVHGRRTAICRAGRGGFKDTTPDELLSAVMTAVLKDVNLRPEQ 82

Query: 91  VGDIVVGTVLGPGSERAIECRMAAFYAGFPDTVPLRTVNRQCSSGLQAVADVAAYIKAGF 150
           +GDI VG VL PG+  AI  R+A F +  P+TVPL TVNRQCSSGLQAVA +A  I+ G 
Sbjct: 83  LGDICVGNVLQPGAG-AIMARIAQFLSDIPETVPLSTVNRQCSSGLQAVASIAGGIRNGS 141

Query: 151 YDIGIGAGLECMTQDTISGVRKTNPKVEIFAQARDCLLSMGITSENVAQRYGVTRQEQDQ 210
           YDIG+  G+E M+            ++    +ARDCL+ MGITSENVA+R+G++R++QD 
Sbjct: 142 YDIGMACGVESMSLADRGNPGNITSRLMEKEKARDCLIPMGITSENVAERFGISREKQDT 201

Query: 211 AAVESHRRAAAATASGKFKDEIIPVSTKFVDPKTGEEKQIIVSVDDGIRPNANLVDLAKL 270
            A+ S ++AA A + G F+ EI+PV+T   D K G ++ I V+ D+GIRP+  +  LAKL
Sbjct: 202 FALASQQKAARAQSKGCFQAEIVPVTTTVHDDK-GTKRSITVTQDEGIRPSTTMEGLAKL 260

Query: 271 KPAFKKDGTTTAGNASQVSDGAAAVLLMKRSVAVQKGLPILGIFRSFSAVGVDPAVMGVG 330
           KPAFKKDG+TTAGN+SQVSDGAAA+LL +RS A + GLPILG+ RS++ VGV P +MG+G
Sbjct: 261 KPAFKKDGSTTAGNSSQVSDGAAAILLARRSKAEELGLPILGVLRSYAVVGVPPDIMGIG 320

Query: 331 PAFAIPAAVKSAGLELSNIDLYEINEAFASQFVYSCKKLGLDPTKVNVNGGAMAFGHPLG 390
           PA+AIP A++ AGL +S++D++EINEAFASQ  Y  +KL L P KVN  GGA+A GHPLG
Sbjct: 321 PAYAIPVALQKAGLTVSDVDIFEINEAFASQAAYCVEKLRLPPEKVNPLGGAVALGHPLG 380

Query: 391 ATGARCVATLLNEMKRRGKDCRFGVISMCIGSGMGAAAVFE 431
            TGAR V TLLNE+KRRGK   +GV+SMCIG+GMGAAAVFE
Sbjct: 381 CTGARQVITLLNELKRRGKRA-YGVVSMCIGTGMGAAAVFE 420


>THIK_YARLI (Q05493) 3-ketoacyl-CoA thiolase, peroxisomal precursor
           (EC 2.3.1.16) (Beta-ketothiolase) (Acetyl-CoA
           acyltransferase) (Peroxisomal 3-oxoacyl-CoA thiolase)
          Length = 414

 Score =  381 bits (978), Expect = e-105
 Identities = 207/392 (52%), Positives = 274/392 (69%), Gaps = 5/392 (1%)

Query: 39  TGGSENDVVIVAAYRTAICKAKRGGFKDTLPDDLLASVLKAVIEKTNVEPSEVGDIVVGT 98
           T  + +DVVI AAYRTA  K  +G FKDT   +LLAS+L+ +++++ ++P  +GD+V G 
Sbjct: 23  TSKNPDDVVITAAYRTAHTKGGKGLFKDTSSSELLASLLEGLVKESKIDPKLIGDVVCGN 82

Query: 99  VLGPGSERAIECRMAAFYAGFPDTVPLRTVNRQCSSGLQAVADVAAYIKAGFYDIGIGAG 158
           VL  G+  A E R A   AG P+TVP   +NRQCSSGL AV DVA  I+AG  DIGIG G
Sbjct: 83  VLAAGAG-ATEHRAACLVAGIPETVPFVALNRQCSSGLMAVNDVANKIRAGQIDIGIGCG 141

Query: 159 LECMT-QDTISGVRKTNPKVEIFAQARDCLLSMGITSENVAQRYGVTRQEQDQAAVESHR 217
           +E M+ Q   + V   + K +   +A+ CL+ MGITSENVA +Y V+R+ QD  A +S+ 
Sbjct: 142 VESMSNQYGPNSVTPFSNKFQNNEEAKKCLIPMGITSENVAAKYNVSRKAQDAFAAKSYE 201

Query: 218 RAAAATASGKFKDEIIPVSTKFVDPKTGEEKQIIVSVDDGIRPNANLVDLAKLKPAFKKD 277
           +AAAA A+GKF  EI+P+ T  +D    E K++ V+ DDGIRP      L KLKPAF  +
Sbjct: 202 KAAAAQAAGKFDQEILPIKTTVLDDDDNE-KEVTVNKDDGIRPGVTAEKLGKLKPAFSAE 260

Query: 278 GTTTAGNASQVSDGAAAVLLMKRSVAVQKGLPILGIFRSFSAVGVDPAVMGVGPAFAIPA 337
           GTT AGNASQ+SDGA AVLLM+RSVA + G PIL  F     VGV P +MG+GPA+AIPA
Sbjct: 261 GTTHAGNASQISDGAGAVLLMRRSVAEKLGQPILAKFVHCKTVGVPPELMGIGPAYAIPA 320

Query: 338 AVKSAGLELSNIDLYEINEAFASQFVYSCKKLGLDPTKVNVNGGAMAFGHPLGATGARCV 397
            ++  GL ++++D++EINEAFASQ ++S +  G+D +KVN  GGA+A GHPLGATGAR  
Sbjct: 321 VLEDLGLTVNDVDVFEINEAFASQALFSIQHCGIDESKVNPRGGAIAIGHPLGATGARQF 380

Query: 398 ATLLNEMKRRGKDCRFGVISMCIGSGMGAAAV 429
           ATLL+E+K  GK  + GV SMCIG+GMGAA++
Sbjct: 381 ATLLSELKESGK--KVGVTSMCIGTGMGAASL 410


>THIL_CANTR (P33291) 3-ketoacyl-CoA thiolase B, peroxisomal
           precursor (EC 2.3.1.16) (Beta-ketothiolase B)
           (Acetyl-CoA acyltransferase B) (Peroxisomal
           3-oxoacyl-CoA thiolase B) (Thiolase IB)
          Length = 408

 Score =  340 bits (873), Expect = 3e-93
 Identities = 189/391 (48%), Positives = 256/391 (65%), Gaps = 10/391 (2%)

Query: 44  NDVVIVAAYRTAICKAKRGGFKDTLPDDLLASVLKAVIEKTNVEPSEVGDIVVGTVLGPG 103
           +DVVIVAAYRTAI K  +G F++   + +L   LK  I+KTN++PS + D+ +G VL   
Sbjct: 25  DDVVIVAAYRTAIGKGFKGSFRNVHSEFILTEFLKEFIKKTNIDPSLIEDVAIGNVLNQA 84

Query: 104 SERAIECRMAAFYAGFPDTVPLRTVNRQCSSGLQAVADVAAYIKAGFYDIGIGAGLECMT 163
           +  A E R A   AG P T     VNR CSSGL A++D+A  IK G  + G+  G E M+
Sbjct: 85  AG-ATEHRGACLAAGIPYTAAFIAVNRFCSSGLMAISDIANKIKTGEIECGLAGGAESMS 143

Query: 164 QDTISG--VRKTNPKVEIFAQARDCLLSMGITSENVAQRYGVTRQEQDQAAVESHRRAAA 221
            +        + +P +   AQ   CL+ MGIT+ENVA ++ ++R+ QD+ A +S+ +AA 
Sbjct: 144 TNYRDPRVAPRIDPHLADDAQMEKCLIPMGITNENVANQFNISRERQDEFAAKSYNKAAK 203

Query: 222 ATASGKFKDEIIPVSTKFVDPKTGEEKQIIVSVDDGIRPNANLVDLAKLKPAFKKDGTTT 281
           A ASG FK EI+P+ +  +    G EK+IIV  D+G R       L KL+PAF  DGTTT
Sbjct: 204 AVASGAFKSEILPIRS-IIRNSDGTEKEIIVDTDEGPREGVTAESLGKLRPAF--DGTTT 260

Query: 282 AGNASQVSDGAAAVLLMKRSVAVQKGLPILGIFRSFSAVGVDPAVMGVGPAFAIPAAVKS 341
           AGNASQVSDGAAAVLLMKRS+A  KG PI+G +   S  GV P +MGVGPAFAIP  +K 
Sbjct: 261 AGNASQVSDGAAAVLLMKRSLAEAKGYPIIGKYVLCSTAGVPPEIMGVGPAFAIPEVLKR 320

Query: 342 AGLELSNIDLYEINEAFASQFVYSCKKLGLDPTKVNVNGGAMAFGHPLGATGARCVATLL 401
            GL + +ID++EINEAFA+Q +YS +++ +   K+N+NGGA+A GHPLG TGAR  AT++
Sbjct: 321 TGLTVDDIDVFEINEAFAAQCLYSAEQVNVPEEKLNINGGAIALGHPLGETGARQYATII 380

Query: 402 NEMKRRGKDCRFGVISMCIGSGMGAAAVFER 432
             +    K  + G+ SMCIGSGMG+A++  R
Sbjct: 381 PLL----KPGQIGLTSMCIGSGMGSASILVR 407


>THIK_CANTR (P33290) 3-ketoacyl-CoA thiolase A, peroxisomal
           precursor (EC 2.3.1.16) (Beta-ketothiolase A)
           (Acetyl-CoA acyltransferase A) (Peroxisomal
           3-oxoacyl-CoA thiolase A) (Thiolase IA)
          Length = 408

 Score =  338 bits (867), Expect = 2e-92
 Identities = 187/391 (47%), Positives = 255/391 (64%), Gaps = 10/391 (2%)

Query: 44  NDVVIVAAYRTAICKAKRGGFKDTLPDDLLASVLKAVIEKTNVEPSEVGDIVVGTVLGPG 103
           +DVVIVAAYRTAI K  +G F+    + +L   LK  I+KTN++PS + D+ +G VL   
Sbjct: 25  DDVVIVAAYRTAIGKGFKGSFRSVRSEFILTEFLKEFIKKTNIDPSLIEDVAIGNVLNQA 84

Query: 104 SERAIECRMAAFYAGFPDTVPLRTVNRQCSSGLQAVADVAAYIKAGFYDIGIGAGLECMT 163
           +  A E R A   AG P T     VNR CSSGL A++D+A  IK G  + G+  G E M+
Sbjct: 85  AG-ATEHRGACLAAGIPYTAAFIAVNRFCSSGLMAISDIANKIKTGEIECGLAGGAESMS 143

Query: 164 QDTISG--VRKTNPKVEIFAQARDCLLSMGITSENVAQRYGVTRQEQDQAAVESHRRAAA 221
            +        + +P +   AQ   CL+ MGIT+ENVA ++ ++R+ QD+ A +S+ +AA 
Sbjct: 144 TNYRDPRVAPRIDPHLADDAQMEKCLIPMGITNENVANQFNISRERQDEFAAKSYNKAAK 203

Query: 222 ATASGKFKDEIIPVSTKFVDPKTGEEKQIIVSVDDGIRPNANLVDLAKLKPAFKKDGTTT 281
           A A+G FK EI+P+ +  +    G EK+IIV  D+G R       L KL+PAF  DGTTT
Sbjct: 204 AVAAGAFKSEILPIRS-IIRNSDGTEKEIIVDTDEGPREGVTAESLGKLRPAF--DGTTT 260

Query: 282 AGNASQVSDGAAAVLLMKRSVAVQKGLPILGIFRSFSAVGVDPAVMGVGPAFAIPAAVKS 341
           AGNASQVSDGAAAVLLMKRS+A  KG PI+G +   S  GV P +MGVGPA+AIP  +K 
Sbjct: 261 AGNASQVSDGAAAVLLMKRSLAEAKGYPIIGKYVLCSTAGVPPEIMGVGPAYAIPEVLKR 320

Query: 342 AGLELSNIDLYEINEAFASQFVYSCKKLGLDPTKVNVNGGAMAFGHPLGATGARCVATLL 401
            GL + +ID++EINEAFA+Q +YS +++ +   K+N+NGGA+A GHPLG TGAR  AT++
Sbjct: 321 TGLTVDDIDVFEINEAFAAQCLYSAEQVNVPEEKLNINGGAIALGHPLGETGARQYATII 380

Query: 402 NEMKRRGKDCRFGVISMCIGSGMGAAAVFER 432
             +    K  + G+ SMCIGSGMG+A++  R
Sbjct: 381 PLL----KPGQIGLTSMCIGSGMGSASILVR 407


>THIK_YEAST (P27796) 3-ketoacyl-CoA thiolase, peroxisomal precursor
           (EC 2.3.1.16) (Beta-ketothiolase) (Acetyl-CoA
           acyltransferase) (Peroxisomal 3-oxoacyl-CoA thiolase)
          Length = 417

 Score =  321 bits (823), Expect = 2e-87
 Identities = 188/398 (47%), Positives = 252/398 (63%), Gaps = 30/398 (7%)

Query: 45  DVVIVAAYRTAICKAKRGGFKDTLPDDLLASVLKAVI----EKTNVEPSEVGDIVVGTVL 100
           DVVIVAA R+AI K  +G FKD   D LL + L   I    E    + + + ++  G VL
Sbjct: 35  DVVIVAANRSAIGKGFKGAFKDVNTDYLLYNFLNEFIGRFPEPLRADLNLIEEVACGNVL 94

Query: 101 GPGSERAIECRMAAFYAGFPDTVPLRTVNRQCSSGLQAVADVAAYIKAGFYDIGIGAGLE 160
             G+  A E R A   +G P + P   +NRQCSSGL AV D+A  IK G  DIG+  G+E
Sbjct: 95  NVGAG-ATEHRAACLASGIPYSTPFVALNRQCSSGLTAVNDIANKIKVGQIDIGLALGVE 153

Query: 161 CMTQDTISGVRKTNP-------KVEIFAQARDCLLSMGITSENVAQRYGVTRQEQDQAAV 213
            MT +     +  NP       +++   +A+ CL+ MGIT+ENVA  + ++R++QD+ A 
Sbjct: 154 SMTNN----YKNVNPLGMISSEELQKNREAKKCLIPMGITNENVAANFKISRKDQDEFAA 209

Query: 214 ESHRRAAAATASGKFKDEIIPVSTKFVDPKTGEEKQIIVSVDDGIRPNANLVDLAKLKPA 273
            S+++A  A   G F+DEI+P+  K  D         I   D+G RPN     L+ ++PA
Sbjct: 210 NSYQKAYKAKNEGLFEDEILPI--KLPDGS-------ICQSDEGPRPNVTAESLSSIRPA 260

Query: 274 FKKD-GTTTAGNASQVSDGAAAVLLMKRSVAVQKGLPILGIFRSFSAVGVDPAVMGVGPA 332
           F KD GTTTAGNASQVSDG A VLL +RSVA Q  LP+LG +  F  VGV P +MGVGPA
Sbjct: 261 FIKDRGTTTAGNASQVSDGVAGVLLARRSVANQLNLPVLGRYIDFQTVGVPPEIMGVGPA 320

Query: 333 FAIPAAVKSAGLELSNIDLYEINEAFASQFVYSCKKLGLDPTKVNVNGGAMAFGHPLGAT 392
           +AIP  +++ GL++ +ID++EINEAFA+Q +Y   KLG+D  KVN  GGA+A GHPLG T
Sbjct: 321 YAIPKVLEATGLQVQDIDIFEINEAFAAQALYCIHKLGIDLNKVNPRGGAIALGHPLGCT 380

Query: 393 GARCVATLLNEMKRRGKDCRFGVISMCIGSGMGAAAVF 430
           GAR VAT+L E+K+     + GV+SMCIG+GMGAAA+F
Sbjct: 381 GARQVATILRELKKD----QIGVVSMCIGTGMGAAAIF 414


>THIL_CHRVO (Q9ZHI1) Acetyl-CoA acetyltransferase (EC 2.3.1.9)
           (Acetoacetyl-CoA thiolase)
          Length = 392

 Score =  290 bits (743), Expect = 4e-78
 Identities = 180/400 (45%), Positives = 244/400 (61%), Gaps = 22/400 (5%)

Query: 45  DVVIVAAYRTAICKAKRGGFKDTLPDDLLASVLKAVIEKTNVEPSEVGDIVVGTVLGPGS 104
           +V IVAA RTAI     G  K   P+ L A+V+KA++EKT V+P +V ++++G VL  GS
Sbjct: 2   EVAIVAAQRTAIGSFGGGLAKIPAPE-LGATVIKALLEKTGVKPEDVSEVILGQVLTAGS 60

Query: 105 ERAIECRMAAFYAGFPDTVPLRTVNRQCSSGLQAVADVAAYIKAGFYDIGIGAGLECMTQ 164
            +    R A   AG P T P  T+N  C SGL+AV   A  I AG  DI I  G E M+ 
Sbjct: 61  GQN-PARQALIKAGLPVTTPATTLNVVCGSGLRAVHLAAQAILAGDADIVIAGGQESMSL 119

Query: 165 D------TISGVRKTNPKVEIFAQARDCLLS------MGITSENVAQRYGVTRQEQDQAA 212
                  +  G R  N ++ +     D L        MGIT+ENVA +YG+ R+EQD  +
Sbjct: 120 SPHILPGSRDGFRMGNAQL-VDTMVNDGLTDAYNAYHMGITAENVAAKYGIGREEQDAFS 178

Query: 213 VESHRRAAAATASGKFKDEIIPVSTKFVDPKTGEEKQIIVSVDDGIRPNANLVDLAKLKP 272
           ++S +RAAAA  +GKF+DEI+PV    V  + G+   +    D+ I+ +A+   LAKL+P
Sbjct: 179 LQSQQRAAAAQKAGKFRDEIVPV---LVPQRKGDP--LAFDADEFIKHDASADGLAKLRP 233

Query: 273 AFKKDGTTTAGNASQVSDGAAAVLLMKRSVAVQKGLPILGIFRSFSAVGVDPAVMGVGPA 332
           AFKKDGT TAGNAS ++DGAAAVLLM    A Q GL  L I + ++  G +P +MG+GP 
Sbjct: 234 AFKKDGTVTAGNASGINDGAAAVLLMSTQKADQLGLKPLAIIKGYALTGCEPEIMGIGPV 293

Query: 333 FAIPAAVKSAGLELSNIDLYEINEAFASQFVYSCKKLGLDPTKVNVNGGAMAFGHPLGAT 392
            A   A+  AG  + ++DL E NEAFA+Q +   K+LG    KVNVNGGA+A GHP+GA+
Sbjct: 294 SATRKALSKAGWTVEDLDLVEANEAFAAQALGVAKELGWGSDKVNVNGGAIALGHPIGAS 353

Query: 393 GARCVATLLNEMKRRGKDCRFGVISMCIGSGMGAAAVFER 432
           G R + TLL+EM+RRG   + G+ ++CIG GMG A   ER
Sbjct: 354 GCRVLVTLLHEMQRRG--AKKGLATLCIGGGMGVALAVER 391


>THLA_CLOAB (P45359) Acetyl-CoA acetyltransferase (EC 2.3.1.9)
           (Acetoacetyl-CoA thiolase)
          Length = 392

 Score =  278 bits (711), Expect = 2e-74
 Identities = 164/400 (41%), Positives = 241/400 (60%), Gaps = 23/400 (5%)

Query: 45  DVVIVAAYRTAICKAKRGGFKDTLPDDLLASVLKAVIEKTNVEPSEVGDIVVGTVLGPGS 104
           +VVI +A RTAI    +   KD    DL A+ +K  ++K  ++P +V ++++G VL  G 
Sbjct: 3   EVVIASAVRTAIGSYGKS-LKDVPAVDLGATAIKEAVKKAGIKPEDVNEVILGNVLQAGL 61

Query: 105 ERAIECRMAAFYAGFPDTVPLRTVNRQCSSGLQAVADVAAYIKAGFYDIGIGAGLECMTQ 164
            +    R A+F AG P  +P  T+N+ C SGL+ V+  A  IKAG  D+ I  G+E M++
Sbjct: 62  GQN-PARQASFKAGLPVEIPAMTINKVCGSGLRTVSLAAQIIKAGDADVIIAGGMENMSR 120

Query: 165 ------DTISGVRKTNPKVEIFAQARDCLLS------MGITSENVAQRYGVTRQEQDQAA 212
                 +   G R  N K  +     D L        MGIT+EN+A+R+ ++R+EQD+ A
Sbjct: 121 APYLANNARWGYRMGNAKF-VDEMITDGLWDAFNDYHMGITAENIAERWNISREEQDEFA 179

Query: 213 VESHRRAAAATASGKFKDEIIPVSTKFVDPKTGEEKQIIVSVDDGIRPNANLVDLAKLKP 272
           + S ++A  A  SG+FKDEI+PV  K      G + + +V  D+  R  + +  LAKLKP
Sbjct: 180 LASQKKAEEAIKSGQFKDEIVPVVIK------GRKGETVVDTDEHPRFGSTIEGLAKLKP 233

Query: 273 AFKKDGTTTAGNASQVSDGAAAVLLMKRSVAVQKGLPILGIFRSFSAVGVDPAVMGVGPA 332
           AFKKDGT TAGNAS ++D AA +++M    A + G+  L    S+ + GVDPA+MG GP 
Sbjct: 234 AFKKDGTVTAGNASGLNDCAAVLVIMSAEKAKELGVKPLAKIVSYGSAGVDPAIMGYGPF 293

Query: 333 FAIPAAVKSAGLELSNIDLYEINEAFASQFVYSCKKLGLDPTKVNVNGGAMAFGHPLGAT 392
           +A  AA++ AG  +  +DL E NEAFA+Q +   K L  D  KVNVNGGA+A GHP+GA+
Sbjct: 294 YATKAAIEKAGWTVDELDLIESNEAFAAQSLAVAKDLKFDMNKVNVNGGAIALGHPIGAS 353

Query: 393 GARCVATLLNEMKRRGKDCRFGVISMCIGSGMGAAAVFER 432
           GAR + TL++ M++R  D + G+ ++CIG G G A + E+
Sbjct: 354 GARILVTLVHAMQKR--DAKKGLATLCIGGGQGTAILLEK 391


>THIL_ALCEU (P14611) Acetyl-CoA acetyltransferase (EC 2.3.1.9)
           (Acetoacetyl-CoA thiolase)
          Length = 393

 Score =  274 bits (700), Expect = 4e-73
 Identities = 173/401 (43%), Positives = 241/401 (59%), Gaps = 24/401 (5%)

Query: 45  DVVIVAAYRTAICKAKRGGFKDTLP-DDLLASVLKAVIEKTNVEPSEVGDIVVGTVLGPG 103
           DVVIV+A RTA+   K GG    +P  +L A V+KA +E+  V+P +V ++++G VL  G
Sbjct: 3   DVVIVSAARTAV--GKFGGSLAKIPAPELGAVVIKAALERAGVKPEQVSEVIMGQVLTAG 60

Query: 104 SERAIECRMAAFYAGFPDTVPLRTVNRQCSSGLQAVADVAAYIKAGFYDIGIGAGLECMT 163
           S +    R AA  AG P  VP  T+N+ C SGL+AV   A  I AG  +I +  G E M+
Sbjct: 61  SGQN-PARQAAIKAGLPAMVPAMTINKVCGSGLKAVMLAANAIMAGDAEIVVAGGQENMS 119

Query: 164 Q------DTISGVRKTNPKVEIFAQARDCLLS------MGITSENVAQRYGVTRQEQDQA 211
                   +  G R  + K+ +     D L        MGIT+ENVA+ YG+TR+ QD+ 
Sbjct: 120 AAPHVLPGSRDGFRMGDAKL-VDTMIVDGLWDVYNQYHMGITAENVAKEYGITREAQDEF 178

Query: 212 AVESHRRAAAATASGKFKDEIIPVSTKFVDPKTGEEKQIIVSVDDGIRPNANLVDLAKLK 271
           AV S  +A AA  +GKF +EI+PV    +  + G+   +    D+ +R  A L  ++ LK
Sbjct: 179 AVGSQNKAEAAQKAGKFDEEIVPV---LIPQRKGDP--VAFKTDEFVRQGATLDSMSGLK 233

Query: 272 PAFKKDGTTTAGNASQVSDGAAAVLLMKRSVAVQKGLPILGIFRSFSAVGVDPAVMGVGP 331
           PAF K GT TA NAS ++DGAAAV++M  + A + GL  L   +S++  GVDP VMG+GP
Sbjct: 234 PAFDKAGTVTAANASGLNDGAAAVVVMSAAKAKELGLTPLATIKSYANAGVDPKVMGMGP 293

Query: 332 AFAIPAAVKSAGLELSNIDLYEINEAFASQFVYSCKKLGLDPTKVNVNGGAMAFGHPLGA 391
             A   A+  A     ++DL EINEAFA+Q +   +++G D +KVNVNGGA+A GHP+GA
Sbjct: 294 VPASKRALSRAEWTPQDLDLMEINEAFAAQALAVHQQMGWDTSKVNVNGGAIAIGHPIGA 353

Query: 392 TGARCVATLLNEMKRRGKDCRFGVISMCIGSGMGAAAVFER 432
           +G R + TLL+EMKRR  D + G+ S+CIG GMG A   ER
Sbjct: 354 SGCRILVTLLHEMKRR--DAKKGLASLCIGGGMGVALAVER 392


>THIL_ZOORA (P07097) Acetyl-CoA acetyltransferase (EC 2.3.1.9)
           (Acetoacetyl-CoA thiolase)
          Length = 391

 Score =  272 bits (695), Expect = 1e-72
 Identities = 170/395 (43%), Positives = 232/395 (58%), Gaps = 20/395 (5%)

Query: 47  VIVAAYRTAICKAKRGGFKDTLPDDLLASVLKAVIEKTNVEPSEVGDIVVGTVLGPGSER 106
           +++A+ RTA+  +  G F +T   +L A+V+ AV+E+  V   EV ++++G VL P  E 
Sbjct: 5   IVIASARTAV-GSFNGAFANTPAHELGATVISAVLERAGVAAGEVNEVILGQVL-PAGEG 62

Query: 107 AIECRMAAFYAGFPDTVPLRTVNRQCSSGLQAVADVAAYIKAGFYDIGIGAGLECMTQDT 166
               R AA  AG P       +N+ C SGL+AVA     I  G   I +  G+E M+   
Sbjct: 63  QNPARQAAMKAGVPQEATAWGMNQLCGSGLRAVALGMQQIATGDASIIVAGGMESMSMAP 122

Query: 167 ----ISGVRKTNPKVEIFAQARDCLLS------MGITSENVAQRYGVTRQEQDQAAVESH 216
               ++G  K      I    +D L        MG T+ENVA+++ ++R EQD  AV S 
Sbjct: 123 HCAHLAGGVKMGDFKMIDTMIKDGLTDAFYGYHMGTTAENVAKQWQLSRDEQDAFAVASQ 182

Query: 217 RRAAAATASGKFKDEIIPVSTKFVDPKTGEEKQIIVSVDDGIRPNANLVDLAKLKPAFKK 276
            +A AA   G+FKDEI+P   K      G +  I V  D+ IR  A L  +AKL+PAF K
Sbjct: 183 NKAEAAQKDGRFKDEIVPFIVK------GRKGDITVDADEYIRHGATLDSMAKLRPAFDK 236

Query: 277 DGTTTAGNASQVSDGAAAVLLMKRSVAVQKGLPILGIFRSFSAVGVDPAVMGVGPAFAIP 336
           +GT TAGNAS ++DGAAA LLM  + A ++G+  LG   S++ VGVDP VMG GP  A  
Sbjct: 237 EGTVTAGNASGLNDGAAAALLMSEAEASRRGIQPLGRIVSWATVGVDPKVMGTGPIPASR 296

Query: 337 AAVKSAGLELSNIDLYEINEAFASQFVYSCKKLGLDPTKVNVNGGAMAFGHPLGATGARC 396
            A++ AG ++ ++DL E NEAFA+Q     K LG DP+ VNVNGGA+A GHP+GA+GAR 
Sbjct: 297 KALERAGWKIGDLDLVEANEAFAAQACAVNKDLGWDPSIVNVNGGAIAIGHPIGASGARI 356

Query: 397 VATLLNEMKRRGKDCRFGVISMCIGSGMGAAAVFE 431
           + TLL EMKRRG   R G+ ++CIG GMG A   E
Sbjct: 357 LNTLLFEMKRRG--ARKGLATLCIGGGMGVAMCIE 389


>ATOB_ECOLI (P76461) Acetyl-CoA acetyltransferase (EC 2.3.1.9)
           (Acetoacetyl-CoA thiolase)
          Length = 394

 Score =  269 bits (688), Expect = 9e-72
 Identities = 171/399 (42%), Positives = 239/399 (59%), Gaps = 24/399 (6%)

Query: 47  VIVAAYRTAICKAKRGGFKDTLPDDLLASVLKAVIEKTNVEPSEVGDIVVGTVLGPGSER 106
           VIV+A RTAI  +  G    T   DL A+V+KA IE+  ++   V ++++G VL  G  +
Sbjct: 5   VIVSAVRTAI-GSFNGSLASTSAIDLGATVIKAAIERAKIDSQHVDEVIMGNVLQAGLGQ 63

Query: 107 AIECRMAAFYAGFPDTVPLRTVNRQCSSGLQAVADVAAYIKAGFYDIGIGAGLECMT--- 163
               R A   +G  +TV   TVN+ C SGL++VA  A  I+AG     +  G+E M+   
Sbjct: 64  N-PARQALLKSGLAETVCGFTVNKVCGSGLKSVALAAQAIQAGQAQSIVAGGMENMSLAP 122

Query: 164 ----QDTISGVRKTNPKVEIFAQARDCLLS------MGITSENVAQRYGVTRQEQDQAAV 213
                   SG R  + +V      RD L+       MGIT+ENVA+ YG+TR+ QD+ A+
Sbjct: 123 YLLDAKARSGYRLGDGQVYDVI-LRDGLMCATHGYHMGITAENVAKEYGITREMQDELAL 181

Query: 214 ESHRRAAAATASGKFKDEIIPVSTKFVDPKTGEEKQIIVSVDDGIRPNANLVDLAKLKPA 273
            S R+AAAA  SG F  EI+PV+          +K  + S D+  + N+    L  L+PA
Sbjct: 182 HSQRKAAAAIESGAFTAEIVPVNV------VTRKKTFVFSQDEFPKANSTAEALGALRPA 235

Query: 274 FKKDGTTTAGNASQVSDGAAAVLLMKRSVAVQKGLPILGIFRSFSAVGVDPAVMGVGPAF 333
           F K GT TAGNAS ++DGAAA+++M+ S A+  GL  L   +S+++ GV PA+MG+GP  
Sbjct: 236 FDKAGTVTAGNASGINDGAAALVIMEESAALAAGLTPLARIKSYASGGVPPALMGMGPVP 295

Query: 334 AIPAAVKSAGLELSNIDLYEINEAFASQFVYSCKKLGLDPTKVNVNGGAMAFGHPLGATG 393
           A   A++ AGL+L++IDL E NEAFA+QF+   K LG D  KVNVNGGA+A GHP+GA+G
Sbjct: 296 ATQKALQLAGLQLADIDLIEANEAFAAQFLAVGKNLGFDSEKVNVNGGAIALGHPIGASG 355

Query: 394 ARCVATLLNEMKRRGKDCRFGVISMCIGSGMGAAAVFER 432
           AR + TLL+ M+ R K    G+ ++CIG G G A V ER
Sbjct: 356 ARILVTLLHAMQARDK--TLGLATLCIGGGQGIAMVIER 392


>THIL_RHIME (P50174) Acetyl-CoA acetyltransferase (EC 2.3.1.9)
           (Acetoacetyl-CoA thiolase)
          Length = 393

 Score =  268 bits (686), Expect = 2e-71
 Identities = 169/401 (42%), Positives = 234/401 (58%), Gaps = 20/401 (4%)

Query: 42  SENDVVIVAAYRTAICKAKRGGFKDTLPDDLLASVLKAVIEKTNVEPSEVGDIVVGTVLG 101
           S   +VI +A RTA+  +  G F +TL  +L A+ +KAV+E+  VE  EV ++++G VL 
Sbjct: 2   SNPSIVIASAARTAV-GSFNGAFGNTLAHELGAAAIKAVLERAGVEAGEVDEVILGQVL- 59

Query: 102 PGSERAIECRMAAFYAGFPDTVPLRTVNRQCSSGLQAVADVAAYIKAGFYDIGIGAGLEC 161
           P  E     R AA  AG P       +N+ C SGL+AVA     I  G   + +  G+E 
Sbjct: 60  PAGEGQNPARQAAMKAGLPQEKTAWGMNQLCGSGLRAVALGMQQIATGDAKVIVAGGMES 119

Query: 162 MTQDT----ISGVRKTNPKVEIFAQARDCLLS------MGITSENVAQRYGVTRQEQDQA 211
           M+       + G  K      I    +D L        MGIT+ENVA+++ +TR+EQD+ 
Sbjct: 120 MSMAPHCAHLRGGVKMGDYKMIDTMIKDGLTDAFYGYHMGITAENVARKWQLTREEQDEF 179

Query: 212 AVESHRRAAAATASGKFKDEIIPVSTKFVDPKTGEEKQIIVSVDDGIRPNANLVDLAKLK 271
           A+ S  +A AA  +G+F DEI+P   K        +  + V  D+ IR  A L  +AKL+
Sbjct: 180 ALASQNKAEAAQKAGRFADEIVPFVVKT------RKGDVNVDQDEYIRHGATLDSIAKLR 233

Query: 272 PAFKKDGTTTAGNASQVSDGAAAVLLMKRSVAVQKGLPILGIFRSFSAVGVDPAVMGVGP 331
           PAF K+GT TAGNAS ++DGAAA LLM  + A ++G+  L    S++  GVDP +MG GP
Sbjct: 234 PAFDKEGTVTAGNASGLNDGAAAALLMTEAEAARRGIQPLARIVSWATAGVDPQIMGTGP 293

Query: 332 AFAIPAAVKSAGLELSNIDLYEINEAFASQFVYSCKKLGLDPTKVNVNGGAMAFGHPLGA 391
             A   A++ AG  +++I+L E NEAFA+Q     K LG DP+ VNVNGGA+A GHP+GA
Sbjct: 294 IPASRKALEKAGWSVADIELVEANEAFAAQACAVNKDLGWDPSIVNVNGGAIAIGHPIGA 353

Query: 392 TGARCVATLLNEMKRRGKDCRFGVISMCIGSGMGAAAVFER 432
           +GAR + TLL EMKRRG     G+ ++CIG GMG A   ER
Sbjct: 354 SGARVLNTLLFEMKRRG--VSKGLATLCIGGGMGVAMCVER 392


>ATOB_HAEIN (P44873) Acetyl-CoA acetyltransferase (EC 2.3.1.9)
           (Acetoacetyl-CoA thiolase)
          Length = 393

 Score =  265 bits (677), Expect = 2e-70
 Identities = 165/400 (41%), Positives = 236/400 (58%), Gaps = 22/400 (5%)

Query: 45  DVVIVAAYRTAICKAKRGGFKDTLPDDLLASVLKAVIEKTNVEPSEVGDIVVGTVLGPGS 104
           +VVIV+A RT I  +  G        DL A V++  I++ N+E + V ++++G VL  G 
Sbjct: 3   NVVIVSAVRTPI-GSFNGALSSVSAVDLGAIVIQEAIKRANIESALVNEVIMGNVLQAGL 61

Query: 105 ERAIECRMAAFYAGFPDTVPLRTVNRQCSSGLQAVADVAAYIKAGFYDIGIGAGLECMTQ 164
            +    R AA  AG    +P  T+N+ C SGL++VA  A  I +G  DI +  G+E M+Q
Sbjct: 62  GQN-PARQAALKAGIEKEIPSLTINKVCGSGLKSVALGAQSIISGDADIVVVGGMENMSQ 120

Query: 165 DTISGVRKTNPKVEIF-AQARDCLLS-----------MGITSENVAQRYGVTRQEQDQAA 212
                  K    V++     RD ++            MGIT+EN+A++YG++RQ QD+ A
Sbjct: 121 APYLLDSKVRQGVKMGNLTLRDTMIEDGLTCASNHYHMGITAENIAEQYGISRQAQDELA 180

Query: 213 VESHRRAAAATASGKFKDEIIPVSTKFVDPKTGEEKQIIVSVDDGIRPNANLVDLAKLKP 272
           + S   A+ A   G F  EI+PV  K        +  IIVS D+  + +     LAKLKP
Sbjct: 181 LRSQTLASQAVQLGVFDKEIVPVMVKT------RKGDIIVSRDEYPKADTTAEGLAKLKP 234

Query: 273 AFKKDGTTTAGNASQVSDGAAAVLLMKRSVAVQKGLPILGIFRSFSAVGVDPAVMGVGPA 332
           AFKK+GT TAGNAS ++DGAAA++L+  S A   GL  +   RS+++ GVDP+VMG+GP 
Sbjct: 235 AFKKEGTVTAGNASGINDGAAALILVSESKAHALGLKAIAKIRSYASGGVDPSVMGLGPV 294

Query: 333 FAIPAAVKSAGLELSNIDLYEINEAFASQFVYSCKKLGLDPTKVNVNGGAMAFGHPLGAT 392
            A   A+K AG+ L +IDL E NEAFASQF+   K L LD  K N++GGA+A GHP+GA+
Sbjct: 295 PATQKALKKAGINLDDIDLIEANEAFASQFLGVGKDLNLDMNKTNIHGGAIALGHPIGAS 354

Query: 393 GARCVATLLNEMKRRGKDCRFGVISMCIGSGMGAAAVFER 432
           GAR + TLL+ +    KD + G+ ++CIG G G + + ER
Sbjct: 355 GARILVTLLHNLIE--KDKKLGLATLCIGGGQGISMIVER 392


>THIL_THIVI (P45363) Acetyl-CoA acetyltransferase (EC 2.3.1.9)
           (Acetoacetyl-CoA thiolase)
          Length = 394

 Score =  265 bits (676), Expect = 2e-70
 Identities = 163/399 (40%), Positives = 232/399 (57%), Gaps = 22/399 (5%)

Query: 46  VVIVAAYRTAICKAKRGGFKDTLP-DDLLASVLKAVIEKTNVEPSEVGDIVVGTVLGPGS 104
           +VIV A RTAI     GG    L   D+  +VLKA+IE+T + P +V ++++G VL  G 
Sbjct: 5   IVIVDAGRTAI--GTFGGALSALQATDIGTTVLKALIERTGIAPEQVSEVILGQVLTAGC 62

Query: 105 ERAIECRMAAFYAGFPDTVPLRTVNRQCSSGLQAVADVAAYIKAGFYDIGIGAGLECMTQ 164
            +    R     AG P TVP  T+N+ C SGL+AV      +  G  +I I  G E M+Q
Sbjct: 63  GQN-PARQTTLMAGLPHTVPAMTINKVCGSGLKAVHLAMQAVACGDAEIVIAGGQESMSQ 121

Query: 165 DTISGVRKTNPKVEIFAQARDCLL-----------SMGITSENVAQRYGVTRQEQDQAAV 213
            +    R    +       +D ++            MG+T+EN+A++Y  TR+ QD  A 
Sbjct: 122 SSHVLPRSREGQRMGDWPMKDTMIVDGLWDAFNQCHMGVTAENIAKKYAFTREAQDAFAA 181

Query: 214 ESHRRAAAATASGKFKDEIIPVSTKFVDPKTGEEKQIIVSVDDGIRPNANLVDLAKLKPA 273
            S ++A AA  SG+F DEIIPVS   +  + G+   ++   D+  RP      L +L+PA
Sbjct: 182 ASQQKAEAAIQSGRFADEIIPVS---IPQRKGDP--LVFDTDEFPRPGTTAETLGRLRPA 236

Query: 274 FKKDGTTTAGNASQVSDGAAAVLLMKRSVAVQKGLPILGIFRSFSAVGVDPAVMGVGPAF 333
           F K GT TAGNAS ++DGAA V++MK S A + GL  +    +FS+ GVDPA+MG GP  
Sbjct: 237 FDKQGTVTAGNASGINDGAAMVVVMKESKAKELGLTPMARLVAFSSAGVDPAIMGTGPIP 296

Query: 334 AIPAAVKSAGLELSNIDLYEINEAFASQFVYSCKKLGLDPTKVNVNGGAMAFGHPLGATG 393
           A    +K AG   +++DL E NEAFA+Q +   +++G D +KVNVNGGA+A GHP+GA+G
Sbjct: 297 ASTDCLKKAGWAPADLDLVEANEAFAAQAMSVNQEMGWDLSKVNVNGGAIAIGHPIGASG 356

Query: 394 ARCVATLLNEMKRRGKDCRFGVISMCIGSGMGAAAVFER 432
           AR + TLL EM++R  D + G+ ++CIG G G A   ER
Sbjct: 357 ARVLVTLLYEMQKR--DAKKGLATLCIGGGQGVALAVER 393


>YQEF_ECOLI (Q46939) Probable acetyl-CoA acetyltransferase (EC
           2.3.1.9) (Acetoacetyl-CoA thiolase)
          Length = 393

 Score =  256 bits (654), Expect = 8e-68
 Identities = 156/402 (38%), Positives = 239/402 (58%), Gaps = 23/402 (5%)

Query: 45  DVVIVAAYRTAICKAKRGGFKDTLPDDLLASVLKAVIEKTNVEPSEVGDIVVGTVLGPGS 104
           DVVIV A RT I    RG        +L + V+KA+IE+T V    V ++++G VL  G+
Sbjct: 3   DVVIVGALRTPI-GCFRGALAGHSAVELGSLVVKALIERTGVPAYAVDEVILGQVLTAGA 61

Query: 105 ERAIECRMAAFYAGFPDTVPLRTVNRQCSSGLQAVADVAAYIKAGFYDIGIGAGLECMTQ 164
            +    R +A   G P++V   T+N  C SGL+A+      I+ G  DI I  G E M++
Sbjct: 62  GQN-PARQSAIKGGLPNSVSAITINDVCGSGLKALHLATQAIQCGEADIVIAGGQENMSR 120

Query: 165 ------DTISGVRKTNPKVEIFAQARDCLLS------MGITSENVAQRYGVTRQEQDQAA 212
                 D+ +G +  N ++ + +   D L        +G+T+EN+A+ YG++RQ QD  A
Sbjct: 121 APHVLTDSRTGAQLGNSQL-VDSLVHDGLWDAFNDYHIGVTAENLAREYGISRQLQDAYA 179

Query: 213 VESHRRAAAATASGKFKDEIIPVSTKFVDPKTGEEKQIIVSVDDGIRPNANLVDLAKLKP 272
           + S ++A AA  +G+FKDEI+PV T+         + ++V  D+  R +A+   LA+L P
Sbjct: 180 LSSQQKARAAIDAGRFKDEIVPVMTQ------SNGQTLVVDTDEQPRTDASAEGLARLNP 233

Query: 273 AFKKDGTTTAGNASQVSDGAAAVLLMKRSVAVQKGLPILGIFRSFSAVGVDPAVMGVGPA 332
           +F   G+ TAGNAS ++DGAAAV++M  + A    LP+L   R+F++VGVDPA+MG+ P 
Sbjct: 234 SFDSLGSVTAGNASSINDGAAAVMMMSEAKARALNLPVLARIRAFASVGVDPALMGIAPV 293

Query: 333 FAIPAAVKSAGLELSNIDLYEINEAFASQFVYSCKKLGLDPTKVNVNGGAMAFGHPLGAT 392
           +A    ++  G +L+ +DL E NEAFA+Q +   K L  D  +VNVNGGA+A GHP+GA+
Sbjct: 294 YATRRCLERVGWQLAEVDLIEANEAFAAQALSVGKMLEWDERRVNVNGGAIALGHPIGAS 353

Query: 393 GARCVATLLNEMKRRGKDCRFGVISMCIGSGMGAAAVFERGD 434
           G R + +L++EM +R  + R G+ ++CIG G G A   ER +
Sbjct: 354 GCRILVSLVHEMVKR--NARKGLATLCIGGGQGVALTIERDE 393


>THIL_CHRVI (P45369) Acetyl-CoA acetyltransferase (EC 2.3.1.9)
           (Acetoacetyl-CoA thiolase)
          Length = 394

 Score =  256 bits (653), Expect = 1e-67
 Identities = 158/403 (39%), Positives = 235/403 (58%), Gaps = 23/403 (5%)

Query: 42  SENDVVIVAAYRTAICKAKRGGFKDTLP-DDLLASVLKAVIEKTNVEPSEVGDIVVGTVL 100
           SEN +VIV A R+AI     GG   +L   ++  +VLK ++ +T + P ++ ++++G VL
Sbjct: 2   SEN-IVIVDAGRSAI--GTFGGSLSSLSATEIGTAVLKGLLARTGLAPEQIDEVILGQVL 58

Query: 101 GPGSERAIECRMAAFYAGFPDTVPLRTVNRQCSSGLQAVADVAAYIKAGFYDIGIGAGLE 160
             G  +    R    +AG P +VP  T+N+ C SGL+AV      I  G  DI I  G E
Sbjct: 59  TAGVGQN-PARQTTLHAGLPHSVPAMTINKVCGSGLKAVHLAMQAIACGDADIVIAGGQE 117

Query: 161 CMTQDTISGVRKTNPKVEIFAQARDCLL-----------SMGITSENVAQRYGVTRQEQD 209
            M+Q +    R  + +       +D ++            MG T+EN+AQ+YG TR++QD
Sbjct: 118 SMSQSSHVLPRSRDGQRMGDWSMKDTMIVDGLWDAFNNYHMGTTAENIAQKYGFTREQQD 177

Query: 210 QAAVESHRRAAAATASGKFKDEIIPVSTKFVDPKTGEEKQIIVSVDDGIRPNANLVDLAK 269
             A  S ++  AA  +G+F+DEIIP+    +  + G+ K  +   D+  R       L K
Sbjct: 178 AFAAASQQKTEAAQKAGRFQDEIIPIE---IPQRKGDPK--VFDADEFPRHGTTAESLGK 232

Query: 270 LKPAFKKDGTTTAGNASQVSDGAAAVLLMKRSVAVQKGLPILGIFRSFSAVGVDPAVMGV 329
           L+PAF KDG+ TAGNAS ++DGAA V++MK S A + GL  +    +F++ GVDPA+MG 
Sbjct: 233 LRPAFSKDGSVTAGNASGINDGAAMVVVMKESKAKELGLKPMARLVAFASAGVDPAIMGT 292

Query: 330 GPAFAIPAAVKSAGLELSNIDLYEINEAFASQFVYSCKKLGLDPTKVNVNGGAMAFGHPL 389
           GP  A    ++ AG   +++DL E NEAFA+Q +   + +G D +KVNVNGGA+A GHP+
Sbjct: 293 GPIPASTKCLEKAGWTPADLDLIEANEAFAAQAMSVNQDMGWDLSKVNVNGGAIAIGHPI 352

Query: 390 GATGARCVATLLNEMKRRGKDCRFGVISMCIGSGMGAAAVFER 432
           GA+GAR + TLL EM++R  D + G+ ++CIG G G A   ER
Sbjct: 353 GASGARVLVTLLYEMQKR--DAKKGLATLCIGGGQGVALAVER 393


>THIL_PARDE (P54810) Acetyl-CoA acetyltransferase (EC 2.3.1.9)
           (Acetoacetyl-CoA thiolase)
          Length = 391

 Score =  255 bits (652), Expect = 1e-67
 Identities = 159/396 (40%), Positives = 227/396 (57%), Gaps = 20/396 (5%)

Query: 47  VIVAAYRTAICKAKRGGFKDTLPDDLLASVLKAVIEKTNVEPSEVGDIVVGTVLGPGSER 106
           VIV+A RT +  +  G F +    +L A VLKAV+E+  ++PSEV + ++G VL   ++ 
Sbjct: 5   VIVSAARTPV-GSFLGSFANLPAHELGAIVLKAVVERAGIDPSEVSETILGQVL-TAAQG 62

Query: 107 AIECRMAAFYAGFPDTVPLRTVNRQCSSGLQAVADVAAYIKAGFYDIGIGAGLECMTQDT 166
               R A    G P       +N+ C SGL+ VA  A  +  G   I +  G E M+   
Sbjct: 63  QNPARQAHIKVGLPRESAAWVINQVCGSGLRTVALAAQQVLLGDARIVVAGGQESMSLAP 122

Query: 167 ----ISGVRKTNPKVEIFAQARDCLLS------MGITSENVAQRYGVTRQEQDQAAVESH 216
               I+  +K      +    +D L        MG T+ENVA ++ ++R EQDQ AV S 
Sbjct: 123 HAAYIAPGQKMGDMKMLDTMIKDGLWDAFNDYHMGTTAENVAGKWEISRAEQDQFAVASQ 182

Query: 217 RRAAAATASGKFKDEIIPVSTKFVDPKTGEEKQIIVSVDDGIRPNANLVDLAKLKPAFKK 276
            +A AA  +GKF DEI+PV+ K        + + +V  D+ IR  A L  +  ++PAF K
Sbjct: 183 NKAEAAQKAGKFADEIVPVTIK------SRKGETVVDADEYIRHGATLEAMENVRPAFSK 236

Query: 277 DGTTTAGNASQVSDGAAAVLLMKRSVAVQKGLPILGIFRSFSAVGVDPAVMGVGPAFAIP 336
           +GT TAGNAS ++DGAAAVL+M    A ++GL  L    S++  GVDP +MG GP  A  
Sbjct: 237 EGTVTAGNASGLNDGAAAVLVMTEDEAARRGLTPLARIASYATAGVDPQIMGTGPIPASR 296

Query: 337 AAVKSAGLELSNIDLYEINEAFASQFVYSCKKLGLDPTKVNVNGGAMAFGHPLGATGARC 396
            A++ AG  + ++DL E NEAFA+Q +   + +G DP+ VNVNGGA+A GHP+GA+G R 
Sbjct: 297 KALEKAGWSVGDLDLVEANEAFAAQAIAVNRDMGWDPSIVNVNGGAIAIGHPIGASGCRI 356

Query: 397 VATLLNEMKRRGKDCRFGVISMCIGSGMGAAAVFER 432
           + TLL EM+RR  D + G+ ++CIG GMG A   ER
Sbjct: 357 LNTLLFEMQRR--DAKKGLATLCIGGGMGVALCLER 390


>THIK_PSEFR (P28790) 3-ketoacyl-CoA thiolase (EC 2.3.1.16) (Fatty
           oxidation complex beta subunit) (Beta-ketothiolase)
           (Acetyl-CoA acyltransferase)
          Length = 390

 Score =  253 bits (646), Expect = 7e-67
 Identities = 161/393 (40%), Positives = 229/393 (57%), Gaps = 14/393 (3%)

Query: 45  DVVIVAAYRTAICKAKRGGFKDTLPDDLLASVLKAVIEKTN-VEPSEVGDIVVGTVLGPG 103
           DVVIV   RT + ++K G  ++T  +D+ A ++  V+E+ + V+P EV D++ G V    
Sbjct: 6   DVVIVDFGRTPMGRSKGGMHRNTRAEDMSAHLISKVLERNSKVDPGEVEDVIWGCVNQTL 65

Query: 104 SERAIECRMAAFYAGFPDTVPLRTVNRQCSSGLQAVADVAAYIKAGFYDIGIGAGLECMT 163
            +     RMA+     P T   +TV+R C S + A+   A  I  G  D+ +  G+E M 
Sbjct: 66  EQGWNIARMASLMTQIPHTSAAQTVSRLCGSSMSALHTAAQAIMTGNGDVFVVGGVEHMG 125

Query: 164 QDTISGVRKTNPKVEIFAQARDCLLSMGITSENVAQRYGVTRQEQDQAAVESHRRAAAAT 223
             ++      NP + ++A     +  MG+T+E + + +G++R++QD  AV SH+ A  AT
Sbjct: 126 HVSMMHGVDPNPHMSLYAAKASGM--MGLTAEMLGKMHGISREQQDAFAVRSHQLAHKAT 183

Query: 224 ASGKFKDEIIPVSTKFVDPKTGEEKQIIVSVDDGIRPNANLVDLAKLKPAFK-KDGTTTA 282
             GKFKDEIIP+       + G  K  I   D+ IRP+  L  LA LKPAF  K GT TA
Sbjct: 184 VEGKFKDEIIPMQGY---DENGFLK--IFDYDETIRPDTTLESLAALKPAFNPKGGTVTA 238

Query: 283 GNASQVSDGAAAVLLMKRSVAVQKGLPILGIFRSFSAVGVDPAVMGVGPAFAIPAAVKSA 342
           G +SQ++DGA+ +++M    A   GL  L + RS +  GVDPA+MG GP  A   A+K A
Sbjct: 239 GTSSQITDGASCMIVMSAQRAKDLGLEPLAVIRSMAVAGVDPAIMGYGPVPATQKALKRA 298

Query: 343 GLELSNIDLYEINEAFASQFVYSCKKLG-LDP--TKVNVNGGAMAFGHPLGATGARCVAT 399
           GL +++ID  E+NEAFA+Q +   K L  LD    KVN++GGA+A GHP G +GAR   T
Sbjct: 299 GLNMADIDFIELNEAFAAQALPVLKDLKVLDKMNEKVNLHGGAIALGHPFGCSGARISGT 358

Query: 400 LLNEMKRRGKDCRFGVISMCIGSGMGAAAVFER 432
           LLN MK+ G    FG+ +MCIG G G A VFER
Sbjct: 359 LLNVMKQNGG--TFGLSTMCIGLGQGIATVFER 389


>THIK_SALTY (Q9L6L6) 3-ketoacyl-CoA thiolase (EC 2.3.1.16) (Fatty
           oxidation complex beta subunit) (Beta-ketothiolase)
           (Acetyl-CoA acyltransferase)
          Length = 387

 Score =  250 bits (639), Expect = 4e-66
 Identities = 162/392 (41%), Positives = 227/392 (57%), Gaps = 14/392 (3%)

Query: 46  VVIVAAYRTAICKAKRGGFKDTLPDDLLASVLKAVIEKT-NVEPSEVGDIVVGTVLGPGS 104
           VVIV A RT + ++K G F++   +DL A ++++++ +  ++  + + DI  G V     
Sbjct: 4   VVIVDAIRTPMGRSKGGAFRNVRAEDLSAHLMRSLLARNPSLTAATLDDIYWGCVQQTLE 63

Query: 105 ERAIECRMAAFYAGFPDTVPLRTVNRQCSSGLQAVADVAAYIKAGFYDIGIGAGLECMTQ 164
           +     R AA  A  P +VP  TVNR C S +QA+ D A  I  G   + +  G+E M  
Sbjct: 64  QGFNIARNAALLAEIPHSVPAVTVNRLCGSSMQALHDAARMIMTGDAQVCLVGGVEHMGH 123

Query: 165 DTISGVRKTNPKVEIFAQARDCLLSMGITSENVAQRYGVTRQEQDQAAVESHRRAAAATA 224
             +S     +P +            MG+T+E +++ +G++R+ QDQ A  SH RA AAT 
Sbjct: 124 VPMSHGVDFHPGLS--RNVAKAAGMMGLTAEMLSRLHGISREMQDQFAARSHARAWAATQ 181

Query: 225 SGKFKDEIIPVSTKFVDPKTGEEKQIIVSVDDGIRPNANLVDLAKLKPAFKK-DGTTTAG 283
           SG FK EIIP      D   G  KQ   + D+ IRP   +  L+ L+PAF    GT TAG
Sbjct: 182 SGAFKTEIIPTGGHDAD---GVLKQF--NYDEVIRPETTVEALSTLRPAFDPVSGTVTAG 236

Query: 284 NASQVSDGAAAVLLMKRSVAVQKGLPILGIFRSFSAVGVDPAVMGVGPAFAIPAAVKSAG 343
            +S +SDGAAA+L+M  S A + GL      RS + VG DP++MG GP  A   A+K AG
Sbjct: 237 TSSALSDGAAAMLVMSESRARELGLKPRARIRSMAVVGCDPSIMGYGPVPASKLALKKAG 296

Query: 344 LELSNIDLYEINEAFASQFVYSCKKLGL---DPTKVNVNGGAMAFGHPLGATGARCVATL 400
           L  S+ID++E+NEAFA+Q +   K LGL      K+N+NGGA+A GHPLG +GAR   TL
Sbjct: 297 LSASDIDVFEMNEAFAAQILPCIKDLGLMEQIDEKINLNGGAIALGHPLGCSGARISTTL 356

Query: 401 LNEMKRRGKDCRFGVISMCIGSGMGAAAVFER 432
           +N M+R  KD +FG+ +MCIG G G A VFER
Sbjct: 357 INLMER--KDAQFGLATMCIGLGQGIATVFER 386


  Database: sprot
    Posted date:  Nov 25, 2004 10:54 AM
  Number of letters in database: 59,974,054
  Number of sequences in database:  164,201
  
Lambda     K      H
   0.318    0.133    0.378 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 49,256,245
Number of Sequences: 164201
Number of extensions: 2056901
Number of successful extensions: 6132
Number of sequences better than 10.0: 84
Number of HSP's better than 10.0 without gapping: 55
Number of HSP's successfully gapped in prelim test: 29
Number of HSP's that attempted gapping in prelim test: 5825
Number of HSP's gapped (non-prelim): 106
length of query: 435
length of database: 59,974,054
effective HSP length: 113
effective length of query: 322
effective length of database: 41,419,341
effective search space: 13337027802
effective search space used: 13337027802
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 67 (30.4 bits)