BLAST2 result
BLASTP 2.2.2 [Dec-14-2001]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= AC126010.8 - phase: 0
(727 letters)
Database: sprot
164,201 sequences; 59,974,054 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
ADP1_YEAST (P25371) Probable ATP-dependent permease precursor 235 4e-61
ABG2_HUMAN (Q9UNQ0) ATP-binding cassette, sub-family G, member 2... 176 1e-43
ABG1_HUMAN (P45844) ATP-binding cassette, sub-family G, member 1... 170 1e-41
YOH5_YEAST (Q08234) Probable ATP-dependent transporter YOL074C/Y... 169 2e-41
ABG1_MOUSE (Q64343) ATP-binding cassette, sub-family G, member 1... 169 2e-41
WHIT_ANOGA (Q27256) White protein 166 3e-40
ABG4_HUMAN (Q9H172) ATP-binding cassette, sub-family G, member 4 163 1e-39
WHIT_DROME (P10090) White protein 161 5e-39
ABG8_MOUSE (Q9DBM0) ATP-binding cassette, sub-family G, member 8... 160 8e-39
ABG8_RAT (P58428) ATP-binding cassette, sub-family G, member 8 (... 160 1e-38
WHIT_LUCCU (Q05360) White protein 158 4e-38
YPC3_CAEEL (Q11180) Putative ABC transporter C05D10.3 in chromos... 156 2e-37
ABG8_HUMAN (Q9H221) ATP-binding cassette, sub-family G, member 8... 155 4e-37
WHIT_ANOAL (Q16928) White protein 154 6e-37
ABG5_MOUSE (Q99PE8) ATP-binding cassette, sub-family G, member 5... 154 6e-37
ABG5_RAT (Q99PE7) ATP-binding cassette, sub-family G, member 5 (... 152 4e-36
ABG5_HUMAN (Q9H222) ATP-binding cassette, sub-family G, member 5... 151 5e-36
WHIT_CERCA (Q17320) White protein 149 3e-35
PDRC_YEAST (Q02785) ATP-dependent permease PDR12 147 7e-35
SNQ2_YEAST (P32568) SNQ2 protein 144 6e-34
>ADP1_YEAST (P25371) Probable ATP-dependent permease precursor
Length = 1049
Score = 235 bits (599), Expect = 4e-61
Identities = 197/718 (27%), Positives = 349/718 (48%), Gaps = 68/718 (9%)
Query: 25 LEFESLTYTVTKKKKVDGKWSNEDVDLLHDITGYAPKGCITAVMGPSGAGKSTLLDGLAG 84
L FE++TY+V DG + +L++I+G G I A+MG SGAGK+TLLD LA
Sbjct: 384 LSFENITYSVPSINS-DGV----EETVLNEISGIVKPGQILAIMGGSGAGKTTLLDILAM 438
Query: 85 RIASGSLKGKVSLDGNSVNASLIKRTSAYIMQEDRLFPMLTVYETLMFAADFRLGP-LSA 143
+ +G + G + ++G S++ + ++ Q+D L P LTV+ET++ +A RL LS
Sbjct: 439 KRKTGHVSGSIKVNGISMDRKSFSKIIGFVDQDDFLLPTLTVFETVLNSALLRLPKALSF 498
Query: 144 VDKRQRVEKLIEQLGLSSSRNTYIGDEGTRGVSGGERRRVSIGVDIIHGPSLLFLDEPTS 203
K+ RV K++E+L + ++ IG+E RG+SGGE+RRVSI +++ P +LFLDEPTS
Sbjct: 499 EAKKARVYKVLEELRIIDIKDRIIGNEFDRGISGGEKRRVSIACELVTSPLVLFLDEPTS 558
Query: 204 GLDSTSALSVIEKLHDIARN-GSTVILTIHQPSSRIQLLLDHLIILARGQLMFQGSLKDV 262
GLD+++A +VIE L ++ + T++L+IHQP S I L D L++L++G++++ G+ K V
Sbjct: 559 GLDASNANNVIECLVRLSSDYNRTLVLSIHQPRSNIFYLFDKLVLLSKGEMVYSGNAKKV 618
Query: 263 GHHLNRMGRKIPKGENPIENLIDVIQEYDQCDFVGVEVLAEFARTGMKPPL--LSDME-- 318
L G P N + LI ++ E G + + +SD+E
Sbjct: 619 SEFLRNEGYICPDNYNIADYLI--------------DITFEAGPQGKRRRIRNISDLEAG 664
Query: 319 -EIISYTNSIAPSPSPLHRGSKYEEKSQDFSYSSQISRRSLNDEFDHSIRSPYNNTPMSW 377
+ N+I + G+ E + ++ +I R L DE D T
Sbjct: 665 TDTNDIDNTIHQTTFTSSDGTTQREWAHLAAHRDEI-RSLLRDEED------VEGTDGRR 717
Query: 378 SASNSAAFLKFTPSRLKNENKVQKPPSHASPGIYTYSSEILPATPTPHSSDYVVDENDYL 437
A+ K + K+ Y +E+ + V+ E D
Sbjct: 718 GATEIDLNTKLLHDKYKDS---------------VYYAEL------SQEIEEVLSEGDEE 756
Query: 438 TPTNSSQEHLGPKFANSYIGETWILMRRNFTNIRRTPELFLSRLMVLTFMGVMMATMFHN 497
+ + G + A ++ + IL R+F N+ R P+L L ++ + + + T+++N
Sbjct: 757 SNVLNGDLPTGQQSAG-FLQQLSILNSRSFKNMYRNPKLLLGNYLLTILLSLFLGTLYYN 815
Query: 498 PKNTLQGITNRLSFFIFTVCLFFFSSNDAVPAFIQERFIFIRETSHNAYRASCYTIASLI 557
N + G NR+ F F + F F + + +F ER IFI+E S+N Y Y I+ ++
Sbjct: 816 VSNDISGFQNRMGLFFFILTYFGFVTFTGLSSFALERIIFIKERSNNYYSPLAYYISKIM 875
Query: 558 TH-MPFLALQALAYAAIVWFALELRGPFIYFFLVLFISLLSTNSFVVFVSSI-VPNYILG 615
+ +P + + + IV+ L FF + I +L + + +I + L
Sbjct: 876 SEVVPLRVVPPILLSLIVYPMTGLNMKDNAFFKCIGILILFNLGISLEILTIGIIFEDLN 935
Query: 616 YAAVIAFTALF--FLFCGYFLSSEDIP-LYWRWMNKVSTMTYPYEGLLMNEYQT----NE 668
+ +++ L LF G F+++++I + ++++ S Y YE LL+NE +T
Sbjct: 936 NSIILSVLVLLGSLLFSGLFINTKNITNVAFKYLKNFSVFYYAYESLLINEVKTLMLKER 995
Query: 669 TFGSNDGVSITGFDILKSLHIGTEEIKKRNNVLIMLGWAVLYRILFYIILRFASKNQR 726
+G N + + G IL + + + +L + V++ I+ Y+ L++ Q+
Sbjct: 996 KYGLN--IEVPGATILSTFGFVVQNLVFDIKILALFN--VVFLIMGYLALKWIVVEQK 1049
>ABG2_HUMAN (Q9UNQ0) ATP-binding cassette, sub-family G, member 2
(Placenta-specific ATP-binding cassette transporter)
(Breast cancer resistance protein)
Length = 655
Score = 176 bits (447), Expect = 1e-43
Identities = 120/353 (33%), Positives = 188/353 (52%), Gaps = 19/353 (5%)
Query: 3 TQGLELETVIDIKHKPVSFTGG--LEFESLTYTVTKKKKVDGKWSNEDVDLLHDITGYAP 60
T G D+K +FT G L F ++ Y V K + ++L +I G
Sbjct: 17 TNGFPATVSNDLK----AFTEGAVLSFHNICYRVKLKSGFLPCRKPVEKEILSNINGIMK 72
Query: 61 KGCITAVMGPSGAGKSTLLDGLAGRIASGSLKGKVSLDGNSVNASLIKRTSAYIMQEDRL 120
G + A++GP+G GKS+LLD LA R L G V ++G A+ K S Y++Q+D +
Sbjct: 73 PG-LNAILGPTGGGKSSLLDVLAARKDPSGLSGDVLINGAPRPANF-KCNSGYVVQDDVV 130
Query: 121 FPMLTVYETLMFAADFRLGP-LSAVDKRQRVEKLIEQLGLSSSRNTYIGDEGTRGVSGGE 179
LTV E L F+A RL ++ +K +R+ ++IE+LGL ++ +G + RGVSGGE
Sbjct: 131 MGTLTVRENLQFSAALRLATTMTNHEKNERINRVIEELGLDKVADSKVGTQFIRGVSGGE 190
Query: 180 RRRVSIGVDIIHGPSLLFLDEPTSGLDSTSALSVIEKLHDIARNGSTVILTIHQPSSRIQ 239
R+R SIG+++I PS+LFLDEPT+GLDS++A +V+ L +++ G T+I +IHQP I
Sbjct: 191 RKRTSIGMELITDPSILFLDEPTTGLDSSTANAVLLLLKRMSKQGRTIIFSIHQPRYSIF 250
Query: 240 LLLDHLIILARGQLMFQGSLKDVGHHLNRMGRKIPKGENPIENLIDVIQEYDQC------ 293
L D L +LA G+LMF G ++ + G NP + +D+I
Sbjct: 251 KLFDSLTLLASGRLMFHGPAQEALGYFESAGYHCEAYNNPADFFLDIINGDSTAVALNRE 310
Query: 294 -DFVGVEVLAEFARTGMKPPLLSDMEEIISYTNSIAPSPSPLHRGSKYEEKSQ 345
DF E++ + PL+ + EI ++ + + LH+ S E+K +
Sbjct: 311 EDFKATEIIEP---SKQDKPLIEKLAEIYVNSSFYKETKAELHQLSGGEKKKK 360
Score = 82.4 bits (202), Expect = 4e-15
Identities = 59/236 (25%), Positives = 106/236 (44%), Gaps = 11/236 (4%)
Query: 451 FANSYIGETWILMRRNFTNIRRTPELFLSRLMVLTFMGVMMATMFHNPKNTLQGITNRLS 510
+ S+ + + +R+F N+ P+ +++++V +G+++ ++ KN GI NR
Sbjct: 369 YTTSFCHQLRWVSKRSFKNLLGNPQASIAQIIVTVVLGLVIGAIYFGLKNDSTGIQNRAG 428
Query: 511 FFIFTVCLFFFSSNDAVPAFIQERFIFIRETSHNAYRASCYTIASLITH-MPFLALQALA 569
F FSS AV F+ E+ +FI E YR S Y + L++ +P L ++
Sbjct: 429 VLFFLTTNQCFSSVSAVELFVVEKKLFIHEYISGYYRVSSYFLGKLLSDLLPMRMLPSII 488
Query: 570 YAAIVWFALELRGPFIYFFLVLFISLLSTNSFVVFVSSIVPNYILGYAAVIAFTALF--- 626
+ IV+F L L+ FF+++F ++ S +I + A + T F
Sbjct: 489 FTCIVYFMLGLKPKADAFFVMMFTLMMVAYSASSMALAIAAGQSVVSVATLLMTICFVFM 548
Query: 627 FLFCGYFLSSEDIPLYWRWMNKVSTMTYPYEGLLMNEYQTNETFGSN--DGVSITG 680
+F G ++ I + W+ S Y + L Q NE G N G++ TG
Sbjct: 549 MIFSGLLVNLTTIASWLSWLQYFSIPRYGFTAL-----QHNEFLGQNFCPGLNATG 599
>ABG1_HUMAN (P45844) ATP-binding cassette, sub-family G, member 1
(White protein homolog) (ATP-binding cassette
transporter 8)
Length = 678
Score = 170 bits (430), Expect = 1e-41
Identities = 97/264 (36%), Positives = 160/264 (59%), Gaps = 14/264 (5%)
Query: 25 LEFESLTYTVTKKKKVDGKWSNED--VDLLHDITGYAPKGCITAVMGPSGAGKSTLLDGL 82
+EF L+Y+V +G W + LL I+G G + A+MGPSGAGKSTL++ L
Sbjct: 77 IEFRDLSYSVP-----EGPWWRKKGYKTLLKGISGKFNSGELVAIMGPSGAGKSTLMNIL 131
Query: 83 AGRIASGSLKGKVSLDGNSVNASLIKRTSAYIMQEDRLFPMLTVYETLMFAADFRLGPLS 142
AG +G +KG V ++G + ++ S YIMQ+D L P LTV E +M +A +L
Sbjct: 132 AGYRETG-MKGAVLINGLPRDLRCFRKVSCYIMQDDMLLPHLTVQEAMMVSAHLKLQEKD 190
Query: 143 AVDKRQRVEKLIEQLGLSSSRNTYIGDEGTRGVSGGERRRVSIGVDIIHGPSLLFLDEPT 202
+R+ V++++ LGL S NT G +SGG+R+R++I +++++ P ++F DEPT
Sbjct: 191 E-GRREMVKEILTALGLLSCANTRTGS-----LSGGQRKRLAIALELVNNPPVMFFDEPT 244
Query: 203 SGLDSTSALSVIEKLHDIARNGSTVILTIHQPSSRIQLLLDHLIILARGQLMFQGSLKDV 262
SGLDS S V+ + +A+ G ++I TIHQPS+++ L D L +L++GQ +++G + ++
Sbjct: 245 SGLDSASCFQVVSLMKGLAQGGRSIICTIHQPSAKLFELFDQLYVLSQGQCVYRGKVCNL 304
Query: 263 GHHLNRMGRKIPKGENPIENLIDV 286
+L +G P NP + +++V
Sbjct: 305 VPYLRDLGLNCPTYHNPADFVMEV 328
Score = 77.4 bits (189), Expect = 1e-13
Identities = 68/290 (23%), Positives = 132/290 (45%), Gaps = 22/290 (7%)
Query: 451 FANSYIGETWILMRRNFTNIRRTPELFLSRLMVLTFMGVMMATMFHNPKNTLQGITNRLS 510
F+ S + + IL +R F +I R L R+ +G+++ ++ N + + +
Sbjct: 397 FSASCLTQFCILFKRTFLSIMRDSVLTHLRITSHIGIGLLIGLLYLGIGNEAKKVLSNSG 456
Query: 511 FFIFTVCLFFFSS-NDAVPAFIQERFIFIRETSHNAYRASCYTIASLITHMPFLALQALA 569
F F++ F++ V F E +F+RE + Y Y +A + +PF + +A
Sbjct: 457 FLFFSMLFLMFAALMPTVLTFPLEMGVFLREHLNYWYSLKAYYLAKTMADVPFQIMFPVA 516
Query: 570 YAAIVWFALELRGPFIYFFLVLFISLLSTNSFVVFVSSIVPNYILGYAAVIAFTALF--- 626
Y +IV++ + F VLF +L + S V + ++G A+ A F
Sbjct: 517 YCSIVYWMTSQPSDAVRF--VLFAALGTMTSLVAQSLGL----LIGAASTSLQVATFVGP 570
Query: 627 ------FLFCGYFLSSEDIPLYWRWMNKVSTMTYPYEGLLMNEYQTNETFGSNDGVSITG 680
LF G+F+S + IP Y +WM+ +S + Y +EG++++ Y + D
Sbjct: 571 VTAIPVLLFSGFFVSFDTIPTYLQWMSYISYVRYGFEGVILSIYGLDREDLHCDIDETCH 630
Query: 681 FD----ILKSLHIGTEEIKKRNNVLIMLGWAVLYRILFYIILRFASKNQR 726
F IL+ L + E K + +++ + + R++ Y +LR+ + +R
Sbjct: 631 FQKSEAILRELDV--ENAKLYLDFIVLGIFFISLRLIAYFVLRYKIRAER 678
>YOH5_YEAST (Q08234) Probable ATP-dependent transporter
YOL074C/YOL075C
Length = 1294
Score = 169 bits (429), Expect = 2e-41
Identities = 103/323 (31%), Positives = 172/323 (52%), Gaps = 17/323 (5%)
Query: 41 DGKWSNEDVDLLHDITGYAPKGCITAVMGPSGAGKSTLLDGLAGRIASG-----SLKGKV 95
+G + +E ++L + G I A+MGPSG+GKS+LL+ ++GR+ S G +
Sbjct: 699 EGNFHHETKEILQSVNAIFKPGMINAIMGPSGSGKSSLLNLISGRLKSSVFAKFDTSGSI 758
Query: 96 SLDGNSVNASLIKRTSAYIMQED-RLFPMLTVYETLMFAADFRLGPLSAVDKRQRVEKLI 154
+ V+ + K +Y+ Q+D L LTV ETL +AA RL L+ ++ +R + LI
Sbjct: 759 MFNDIQVSELMFKNVCSYVSQDDDHLLAALTVKETLKYAAALRLHHLTEAERMERTDNLI 818
Query: 155 EQLGLSSSRNTYIGDEGTRGVSGGERRRVSIGVDIIHGPSLLFLDEPTSGLDSTSALSVI 214
LGL N IG+E +G+SGGE+RRV++GV +++ P +L LDEPTSGLDS ++ +++
Sbjct: 819 RSLGLKHCENNIIGNEFVKGISGGEKRRVTMGVQLLNDPPILLLDEPTSGLDSFTSATIL 878
Query: 215 EKLHDIAR-NGSTVILTIHQPSSRIQLLLDHLIILAR-GQLMFQGSLKDVGHHLNRMGRK 272
E L + R G T+I+TIHQP S + ++++LA+ G+ F GS ++ + +G
Sbjct: 879 EILEKLCREQGKTIIITIHQPRSELFKRFGNVLLLAKSGRTAFNGSPDEMIAYFTELGYN 938
Query: 273 IPKGENPIENLIDVIQEYDQCDFVGVEVLAEFARTGMKPPLLSDMEEIISYTNSIAPSPS 332
P N + +D+I Q + + A + D E + SP+
Sbjct: 939 CPSFTNVADFFLDLISVNTQNEQNEISSRARVEKILSAWKANMDNESL---------SPT 989
Query: 333 PLHRGSKYEEKSQDFSYSSQISR 355
P+ +Y ++S YS + +
Sbjct: 990 PISEKQQYSQESFFTEYSEFVRK 1012
Score = 168 bits (425), Expect = 5e-41
Identities = 103/262 (39%), Positives = 155/262 (58%), Gaps = 21/262 (8%)
Query: 45 SNEDVDLLHDITGYAPKGCITAVMGPSGAGKSTLLDGLAGRIA-----SGSLKGKVSLDG 99
S + L++ + P G + AVMG SG+GK+TLL+ LA +I+ +GS++ + G
Sbjct: 38 SKTNTTLVNTFSMDLPSGSVMAVMGGSGSGKTTLLNVLASKISGGLTHNGSIRYVLEDTG 97
Query: 100 NSVNASLIKRTS--------------AYIMQEDRLFPMLTVYETLMFAADFRLGPLSAVD 145
+ N + KR AY+ Q+D L P LT ETL FAAD +L S
Sbjct: 98 SEPNETEPKRAHLDGQDHPIQKHVIMAYLPQQDVLSPRLTCRETLKFAADLKLNS-SERT 156
Query: 146 KRQRVEKLIEQLGLSSSRNTYIGDEGTRGVSGGERRRVSIGVDIIHGPSLLFLDEPTSGL 205
K+ VE+LIE+LGL +T +GD RG+SGGE+RR+SIG +I PS++FLDEPT+GL
Sbjct: 157 KKLMVEQLIEELGLKDCADTLVGDNSHRGLSGGEKRRLSIGTQMISNPSIMFLDEPTTGL 216
Query: 206 DSTSALSVIEKLHDIAR-NGSTVILTIHQPSSRIQLLLDHLIILARGQLMFQGSLKDVGH 264
D+ SA VI+ L +A+ +G T I++IHQP S I LLD + IL++G +++ + +
Sbjct: 217 DAYSAFLVIKTLKKLAKEDGRTFIMSIHQPRSDILFLLDQVCILSKGNVVYCDKMDNTIP 276
Query: 265 HLNRMGRKIPKGENPIENLIDV 286
+ +G +P+ NP + ID+
Sbjct: 277 YFESIGYHVPQLVNPADYFIDL 298
Score = 55.5 bits (132), Expect = 5e-07
Identities = 35/136 (25%), Positives = 62/136 (44%)
Query: 463 MRRNFTNIRRTPELFLSRLMVLTFMGVMMATMFHNPKNTLQGITNRLSFFIFTVCLFFFS 522
++R FT RR+ + ++R+ + +GV+ A F K+ I+NRL + L+F
Sbjct: 1024 VKRQFTTTRRSFDSLMARIAQIPGLGVIFALFFAPVKHNYTSISNRLGLAQESTALYFVG 1083
Query: 523 SNDAVPAFIQERFIFIRETSHNAYRASCYTIASLITHMPFLALQALAYAAIVWFALELRG 582
+ + ER F E + N Y + + +A + +P AL ++ YA A L
Sbjct: 1084 MLGNLACYPTERDYFYEEYNDNVYGIAPFFLAYMTLELPLSALASVLYAVFTVLACGLPR 1143
Query: 583 PFIYFFLVLFISLLST 598
FF ++ S + T
Sbjct: 1144 TAGNFFATVYCSFIVT 1159
Score = 45.4 bits (106), Expect = 5e-04
Identities = 56/268 (20%), Positives = 116/268 (42%), Gaps = 16/268 (5%)
Query: 461 ILMRRNFTNIRRTPELFLSRLMVLTFMGVMMATMFHNP-KNTLQGITNRLSFFIFTVCL- 518
+L RRNF +S +G + +++ P K+++ G+ + + L
Sbjct: 362 VLTRRNFKLNFSDYVTLISTFAEPLIIGTVCGWIYYKPDKSSIGGLRTTTACLYASTILQ 421
Query: 519 -FFFSSNDAVPAFIQERFIFIRETSHNAYRASCYTIASLITHMPFLA---LQALAYAAIV 574
+ + D Q+ ++ RE + + + +A I+ FL+ + + +I
Sbjct: 422 CYLYLLFDTYRLCEQDIALYDRERAEGSVTPLAFIVARKISL--FLSDDFAMTMIFVSIT 479
Query: 575 WFALELRGP---FIYFFLVLFISLLSTNSFVVFVSSIVPNYI-LGYAAVIAFTALFFLFC 630
+F L F Y F V+F+ LS + + ++ ++ + FT L + C
Sbjct: 480 YFMFGLEADARKFFYQFAVVFLCQLSCSGLSMLSVAVSRDFSKASLVGNMTFTVLS-MGC 538
Query: 631 GYFLSSEDIPLYWRWMNKVSTMTYPYEGLLMNEYQTNETFGSNDGVSITGFDILKSLHIG 690
G+F++++ +P+Y RW+ ++ Y + G LM+ TN +++ G IL+
Sbjct: 539 GFFVNAKVMPVYVRWIKYIAFTWYSF-GTLMSSTFTNSYCTTDNLDECLGNQILEVYGFP 597
Query: 691 TEEIKKRNNVLIMLGWAVLYRILFYIIL 718
I +++L W+V Y ++ IIL
Sbjct: 598 RNWITV--PAVVLLCWSVGYFVVGAIIL 623
>ABG1_MOUSE (Q64343) ATP-binding cassette, sub-family G, member 1
(White protein homolog) (ATP-binding cassette
transporter 8)
Length = 666
Score = 169 bits (429), Expect = 2e-41
Identities = 95/264 (35%), Positives = 160/264 (59%), Gaps = 14/264 (5%)
Query: 25 LEFESLTYTVTKKKKVDGKWSNED--VDLLHDITGYAPKGCITAVMGPSGAGKSTLLDGL 82
+EF+ L+Y+V +G W + LL I+G G + A+MGPSGAGKSTL++ L
Sbjct: 77 IEFKDLSYSVP-----EGPWWKKKGYKTLLKGISGKFNSGELVAIMGPSGAGKSTLMNIL 131
Query: 83 AGRIASGSLKGKVSLDGNSVNASLIKRTSAYIMQEDRLFPMLTVYETLMFAADFRLGPLS 142
AG +G +KG V ++G + ++ S YIMQ+D L P LTV E +M +A +L
Sbjct: 132 AGYRETG-MKGAVLINGMPRDLRCFRKVSCYIMQDDMLLPHLTVQEAMMVSAHLKLQEKD 190
Query: 143 AVDKRQRVEKLIEQLGLSSSRNTYIGDEGTRGVSGGERRRVSIGVDIIHGPSLLFLDEPT 202
+R+ V++++ LGL NT G +SGG+R+R++I +++++ P ++F DEPT
Sbjct: 191 E-GRREMVKEILTALGLLPCANTRTGS-----LSGGQRKRLAIALELVNNPPVMFFDEPT 244
Query: 203 SGLDSTSALSVIEKLHDIARNGSTVILTIHQPSSRIQLLLDHLIILARGQLMFQGSLKDV 262
SGLDS S V+ + +A+ G +++ TIHQPS+++ L D L +L++GQ +++G + ++
Sbjct: 245 SGLDSASCFQVVSLMKGLAQGGRSIVCTIHQPSAKLFELFDQLYVLSQGQCVYRGKVSNL 304
Query: 263 GHHLNRMGRKIPKGENPIENLIDV 286
+L +G P NP + +++V
Sbjct: 305 VPYLRDLGLNCPTYHNPADFVMEV 328
Score = 79.0 bits (193), Expect = 4e-14
Identities = 68/290 (23%), Positives = 132/290 (45%), Gaps = 22/290 (7%)
Query: 451 FANSYIGETWILMRRNFTNIRRTPELFLSRLMVLTFMGVMMATMFHNPKNTLQGITNRLS 510
F+ S + + IL +R F +I R L R+ +G+++ ++ N + + +
Sbjct: 385 FSASCLTQFCILFKRTFLSIMRDSVLTHLRITSHIGIGLLIGLLYLGIGNEAKKVLSNSG 444
Query: 511 FFIFTVCLFFFSS-NDAVPAFIQERFIFIRETSHNAYRASCYTIASLITHMPFLALQALA 569
F F++ F++ V F E +F+RE + Y Y +A + +PF + +A
Sbjct: 445 FLFFSMLFLMFAALMPTVLTFPLEMSVFLREHLNYWYSLKAYYLAKTMADVPFQIMFPVA 504
Query: 570 YAAIVWFALELRGPFIYFFLVLFISLLSTNSFVVFVSSIVPNYILGYAAVIAFTALF--- 626
Y +IV++ + F VLF +L + S V + ++G A+ A F
Sbjct: 505 YCSIVYWMTSQPSDAVRF--VLFAALGTMTSLVAQSLGL----LIGAASTSLQVATFVGP 558
Query: 627 ------FLFCGYFLSSEDIPLYWRWMNKVSTMTYPYEGLLMNEYQTNETFGSNDGVSITG 680
LF G+F+S + IP Y +WM+ +S + Y +EG++++ Y + D
Sbjct: 559 VTAIPVLLFSGFFVSFDTIPAYLQWMSYISYVRYGFEGVILSIYGLDREDLHCDIAETCH 618
Query: 681 FD----ILKSLHIGTEEIKKRNNVLIMLGWAVLYRILFYIILRFASKNQR 726
F IL+ L + E K + +++ + + R++ Y +LR+ + +R
Sbjct: 619 FQKSEAILRELDV--ENAKLYLDFIVLGIFFISLRLIAYFVLRYKIRAER 666
>WHIT_ANOGA (Q27256) White protein
Length = 695
Score = 166 bits (419), Expect = 3e-40
Identities = 97/242 (40%), Positives = 144/242 (59%), Gaps = 5/242 (2%)
Query: 51 LLHDITGYAPKGCITAVMGPSGAGKSTLLDGLAGRIASG---SLKGKVSLDGNSVNASLI 107
LL ++TG A G + AVMG SGAGK+TLL+ LA R G S +L+G VNA +
Sbjct: 115 LLKNVTGVAKSGELLAVMGSSGAGKTTLLNALAFRSPPGVKISPNAVRALNGVPVNAEQL 174
Query: 108 KRTSAYIMQEDRLFPMLTVYETLMFAADFRLG-PLSAVDKRQRVEKLIEQLGLSSSRNTY 166
+ AY+ Q+D P LT E L+F A R+G + A K+ RV++++++L L +T
Sbjct: 175 RARCAYVQQDDLFIPSLTTREHLLFQAMLRMGRDVPASVKQHRVQEVLQELSLVKCADTI 234
Query: 167 IGDEGT-RGVSGGERRRVSIGVDIIHGPSLLFLDEPTSGLDSTSALSVIEKLHDIARNGS 225
IG G +G+SGGER+R++ + + P LL DEPTSGLDS A SV++ L +A G
Sbjct: 235 IGAPGRIKGLSGGERKRLAFASETLTDPHLLLCDEPTSGLDSFMAHSVLQVLKGMAMKGK 294
Query: 226 TVILTIHQPSSRIQLLLDHLIILARGQLMFQGSLKDVGHHLNRMGRKIPKGENPIENLID 285
T+ILTIHQPSS + L D ++++A G++ F GS +++G P NP + +
Sbjct: 295 TIILTIHQPSSELYCLFDKILLVAEGRVAFLGSPYQSAEFFSQLGIPCPPNYNPADFYVQ 354
Query: 286 VI 287
++
Sbjct: 355 ML 356
Score = 75.1 bits (183), Expect = 6e-13
Identities = 48/220 (21%), Positives = 99/220 (44%), Gaps = 4/220 (1%)
Query: 451 FANSYIGETWILMRRNFTNIRRTPELFLSRLMVLTFMGVMMATMFHNPKNTLQGITN-RL 509
+ +S+ + + ++ R++ ++ + P L RL+ + ++ +++ G+ N
Sbjct: 414 YRSSWWTQFYCILWRSWLSVLKDPMLVKVRLLQTAMVATLIGSIYFGQVLDQDGVMNING 473
Query: 510 SFFIFTVCLFFFSSNDAVPAFIQERFIFIRETSHNAYRASCYTIASLITHMPFLALQALA 569
S F+F + F + + F E +F+RE YR Y + I +P
Sbjct: 474 SLFLFLTNMTFQNVFAVINVFSAELPVFLREKRSRLYRVDTYFLGKTIAELPLFIAVPFV 533
Query: 570 YAAIVWFALELRGPFIYFFLVLFISLLSTN---SFVVFVSSIVPNYILGYAAVIAFTALF 626
+ +I + + LR ++ LFI L N SF +S + + + F
Sbjct: 534 FTSITYPMIGLRTGATHYLTTLFIVTLVANVSTSFGYLISCASSSISMALSVGPPVVIPF 593
Query: 627 FLFCGYFLSSEDIPLYWRWMNKVSTMTYPYEGLLMNEYQT 666
+F G+FL+S +P Y+++++ +S Y E LL+N++ T
Sbjct: 594 LIFGGFFLNSASVPAYFKYLSYLSWFRYANEALLINQWST 633
>ABG4_HUMAN (Q9H172) ATP-binding cassette, sub-family G, member 4
Length = 646
Score = 163 bits (413), Expect = 1e-39
Identities = 97/272 (35%), Positives = 159/272 (57%), Gaps = 12/272 (4%)
Query: 16 HKPVSFTGGLEFESLTYTVTKKKKVDGKWSNEDVD-LLHDITGYAPKGCITAVMGPSGAG 74
H P +EF L+Y+V + W LL ++G + + +MGPSGAG
Sbjct: 52 HLPKRSAVDIEFVELSYSVREGPC----WRKRGYKTLLKCLSGKFCRRELIGIMGPSGAG 107
Query: 75 KSTLLDGLAGRIASGSLKGKVSLDGNSVNASLIKRTSAYIMQEDRLFPMLTVYETLMFAA 134
KST ++ LAG SG +KG++ ++G ++ S YIMQ+D L P LTV E +M +A
Sbjct: 108 KSTFMNILAGYRESG-MKGQILVNGRPRELRTFRKMSCYIMQDDMLLPHLTVLEAMMVSA 166
Query: 135 DFRLGPLSAVDKRQRVEKLIEQLGLSSSRNTYIGDEGTRGVSGGERRRVSIGVDIIHGPS 194
+ +L V K++ V +++ LGL S +T T +SGG+R+R++I +++++ P
Sbjct: 167 NLKLSEKQEV-KKELVTEILTALGLMSCSHTR-----TALLSGGQRKRLAIALELVNNPP 220
Query: 195 LLFLDEPTSGLDSTSALSVIEKLHDIARNGSTVILTIHQPSSRIQLLLDHLIILARGQLM 254
++F DEPTSGLDS S V+ + +A+ G T+I TIHQPS+++ + D L IL++GQ +
Sbjct: 221 VMFFDEPTSGLDSASCFQVVSLMKSLAQGGRTIICTIHQPSAKLFEMFDKLYILSQGQCI 280
Query: 255 FQGSLKDVGHHLNRMGRKIPKGENPIENLIDV 286
F+G + ++ +L +G P NP + +I+V
Sbjct: 281 FKGVVTNLIPYLKGLGLHCPTYHNPADFIIEV 312
Score = 73.6 bits (179), Expect = 2e-12
Identities = 70/292 (23%), Positives = 132/292 (44%), Gaps = 27/292 (9%)
Query: 451 FANSYIGETWILMRRNFTNIRRTPELFLSRLMVLTFMGVMMATMFHNPKNTLQGITNRLS 510
FA S + + IL +R F +I R L R M +GV++ ++ + + + N
Sbjct: 366 FATSTLTQFCILFKRTFLSILRDTVLTHLRFMSHVVIGVLIGLLYLHIGDDASKVFNNTG 425
Query: 511 FFIFTVCLFFFSS-NDAVPAFIQERFIFIRETSHNAYRASCYTIASLITHMPFLALQALA 569
F++ F++ V F E +F+RE + Y Y +A + +PF + +
Sbjct: 426 CLFFSMLFLMFAALMPTVLTFPLEMAVFMREHLNYWYSLKAYYLAKTMADVPFQVVCPVV 485
Query: 570 YAAIVWFALELRGPFIYFFLVLFISLLSTNSFVVFVSSIVPNYILGYAAVIAF----TAL 625
Y +IV++ F +LF +L + + V ++ V F TA+
Sbjct: 486 YCSIVYWMTGQPAETSRF--LLFSALATATALVAQSLGLLIGAASNSLQVATFVGPVTAI 543
Query: 626 -FFLFCGYFLSSEDIPLYWRWMNKVSTMTYPYEGLLMNEYQTNETFGSNDGVSITGFD-- 682
LF G+F+S + IP Y +W + +S + Y +EG+++ Y G G +T +
Sbjct: 544 PVLLFSGFFVSFKTIPTYLQWSSYLSYVRYGFEGVILTIY------GMERG-DLTCLEER 596
Query: 683 --------ILKSLHIGTEEIKKRNNVLIMLGWAVLYRILFYIILRFASKNQR 726
IL++L + E+ K + L++ + + R+L Y++LR+ K++R
Sbjct: 597 CPFREPQSILRALDV--EDAKLYMDFLVLGIFFLALRLLAYLVLRYRVKSER 646
>WHIT_DROME (P10090) White protein
Length = 687
Score = 161 bits (408), Expect = 5e-39
Identities = 102/288 (35%), Positives = 161/288 (55%), Gaps = 5/288 (1%)
Query: 51 LLHDITGYAPKGCITAVMGPSGAGKSTLLDGLAGRIASG---SLKGKVSLDGNSVNASLI 107
LL ++ G A G + AVMG SGAGK+TLL+ LA R G S G L+G V+A +
Sbjct: 112 LLKNVCGVAYPGELLAVMGSSGAGKTTLLNALAFRSPQGIQVSPSGMRLLNGQPVDAKEM 171
Query: 108 KRTSAYIMQEDRLFPMLTVYETLMFAADFRLGP-LSAVDKRQRVEKLIEQLGLSSSRNTY 166
+ AY+ Q+D LT E L+F A R+ L+ + RV+++I++L LS ++T
Sbjct: 172 QARCAYVQQDDLFIGSLTAREHLIFQAMVRMPRHLTYRQRVARVDQVIQELSLSKCQHTI 231
Query: 167 IGDEG-TRGVSGGERRRVSIGVDIIHGPSLLFLDEPTSGLDSTSALSVIEKLHDIARNGS 225
IG G +G+SGGER+R++ + + P LL DEPTSGLDS +A SV++ L +++ G
Sbjct: 232 IGVPGRVKGLSGGERKRLAFASEALTDPPLLICDEPTSGLDSFTAHSVVQVLKKLSQKGK 291
Query: 226 TVILTIHQPSSRIQLLLDHLIILARGQLMFQGSLKDVGHHLNRMGRKIPKGENPIENLID 285
TVILTIHQPSS + L D ++++A G++ F G+ + + +G + P NP + +
Sbjct: 292 TVILTIHQPSSELFELFDKILLMAEGRVAFLGTPSEAVDFFSYVGAQCPTNYNPADFYVQ 351
Query: 286 VIQEYDQCDFVGVEVLAEFARTGMKPPLLSDMEEIISYTNSIAPSPSP 333
V+ + + +A+ + DME++++ N P P
Sbjct: 352 VLAVVPGREIESRDRIAKICDNFAISKVARDMEQLLATKNLEKPLEQP 399
Score = 92.0 bits (227), Expect = 5e-18
Identities = 71/284 (25%), Positives = 130/284 (45%), Gaps = 22/284 (7%)
Query: 459 TWIL-----MRRNFTNIRRTPELFLSRLMVLTFMGVMMATMFHNPKNTLQGITN-RLSFF 512
TW + + R++ ++ + P L RL+ T + +++ +F + T G+ N + F
Sbjct: 408 TWFMQFRAVLWRSWLSVLKEPLLVKVRLIQTTMVAILIGLIFLGQQLTQVGVMNINGAIF 467
Query: 513 IFTVCLFFFSSNDAVPAFIQERFIFIRETSHNAYRASCYTIASLITHMPFLALQALAYAA 572
+F + F + + F E +F+RE YR Y + I +P L + A
Sbjct: 468 LFLTNMTFQNVFATINVFTSELPVFMREARSRLYRCDTYFLGKTIAELPLFLTVPLVFTA 527
Query: 573 IVWFALELRGPFIYFFLVLFISLLSTN---SFVVFVSSIVPNYILGYAAVIAFTALFFLF 629
I + + LR ++FF L + L N SF +S + + + F LF
Sbjct: 528 IAYPMIGLRAGVLHFFNCLALVTLVANVSTSFGYLISCASSSTSMALSVGPPVIIPFLLF 587
Query: 630 CGYFLSSEDIPLYWRWMNKVSTMTYPYEGLLMNEYQTNE-----TFGSNDGVSITGFDIL 684
G+FL+S +P+Y +W++ +S Y EGLL+N++ E SN +G IL
Sbjct: 588 GGFFLNSGSVPVYLKWLSYLSWFRYANEGLLINQWADVEPGEISCTSSNTTCPSSGKVIL 647
Query: 685 KSLHIGTEEIKKRNNVLIMLGWAVL---YRILFYIILRFASKNQ 725
++L+ ++ L +G A+L +R+L Y+ LR ++ +
Sbjct: 648 ETLNFSAADLP-----LDYVGLAILIVSFRVLAYLALRLRARRK 686
>ABG8_MOUSE (Q9DBM0) ATP-binding cassette, sub-family G, member 8
(Sterolin-2)
Length = 673
Score = 160 bits (406), Expect = 8e-39
Identities = 86/227 (37%), Positives = 138/227 (59%), Gaps = 2/227 (0%)
Query: 62 GCITAVMGPSGAGKSTLLDGLAGRIASGSLK-GKVSLDGNSVNASLIKRTSAYIMQEDRL 120
G + A++G SG G+++LLD + GR G +K G++ ++G L+++ A++ Q D+L
Sbjct: 99 GQMLAIIGSSGCGRASLLDVITGRGHGGKMKSGQIWINGQPSTPQLVRKCVAHVRQHDQL 158
Query: 121 FPMLTVYETLMFAADFRLG-PLSAVDKRQRVEKLIEQLGLSSSRNTYIGDEGTRGVSGGE 179
P LTV ETL F A RL S + +RVE +I +L L NT +G+ RGVSGGE
Sbjct: 159 LPNLTVRETLAFIAQMRLPRTFSQAQRDKRVEDVIAELRLRQCANTRVGNTYVRGVSGGE 218
Query: 180 RRRVSIGVDIIHGPSLLFLDEPTSGLDSTSALSVIEKLHDIARNGSTVILTIHQPSSRIQ 239
RRRVSIGV ++ P +L LDEPTSGLDS +A +++ L +A+ V++++HQP S I
Sbjct: 219 RRRVSIGVQLLWNPGILILDEPTSGLDSFTAHNLVTTLSRLAKGNRLVLISLHQPRSDIF 278
Query: 240 LLLDHLIILARGQLMFQGSLKDVGHHLNRMGRKIPKGENPIENLIDV 286
L D ++++ G ++ G+ + + + +G P+ NP + +D+
Sbjct: 279 RLFDLVLLMTSGTPIYLGAAQQMVQYFTSIGHPCPRYSNPADFYVDL 325
Score = 52.4 bits (124), Expect = 4e-06
Identities = 49/264 (18%), Positives = 114/264 (42%), Gaps = 8/264 (3%)
Query: 462 LMRRNFTNIRRTPELFLSRLMVLTFMGVMMATMFH-NPKNTLQGITNRLSFFIFTVCLFF 520
L+RR +N R L M +++ +++ + L + F+ + F
Sbjct: 402 LIRRQISNDFRDLPTLLIHGSEACLMSLIIGFLYYGHGAKQLSFMDTAALLFMIGALIPF 461
Query: 521 FSSNDAVPAFIQERFIFIRETSHNAYRASCYTIASLITHMPFLALQALAYAAIVWFALEL 580
D V ER + E Y A Y A ++ +P + YA +++ L
Sbjct: 462 NVILDVVSKCHSERSMLYYELEDGLYTAGPYFFAKILGELPEHCAYVIIYAMPIYWLTNL 521
Query: 581 RGP---FIYFFLVLFISLLSTNSFVVFVSSIVPNYILGYAAVIAFTALFFLFCGYFLSSE 637
R F+ FL++++ + + + S+++P + + A F+L G+ ++ +
Sbjct: 522 RPVPELFLLHFLLVWLVVFCCRTMALAASAMLPTFHMSSFFCNALYNSFYLTAGFMINLD 581
Query: 638 DIPLYWRWMNKVSTMTYPYEGLLMNEYQTN--ETFGSNDGVSITGFDILKSLHIGTEEIK 695
++ + W++K+S + + + GL+ ++ + T N SI G ++ ++ + + +
Sbjct: 582 NLWIVPAWISKLSFLRWCFSGLMQIQFNGHLYTTQIGNFTFSILGDTMISAMDLNSHPLY 641
Query: 696 KRNNVLIMLGWAVLYRILFYIILR 719
LI++G + + L+Y+ L+
Sbjct: 642 A--IYLIVIGISYGFLFLYYLSLK 663
>ABG8_RAT (P58428) ATP-binding cassette, sub-family G, member 8
(Sterolin-2)
Length = 694
Score = 160 bits (405), Expect = 1e-38
Identities = 87/227 (38%), Positives = 138/227 (60%), Gaps = 2/227 (0%)
Query: 62 GCITAVMGPSGAGKSTLLDGLAGRIASGSLK-GKVSLDGNSVNASLIKRTSAYIMQEDRL 120
G + A++G +G G++TLLD + GR G +K G++ ++G LI++ A++ Q+D+L
Sbjct: 120 GQMLAIIGSAGCGRATLLDVITGRDHGGKMKSGQIWINGQPSTPQLIQKCVAHVRQQDQL 179
Query: 121 FPMLTVYETLMFAADFRLGP-LSAVDKRQRVEKLIEQLGLSSSRNTYIGDEGTRGVSGGE 179
P LTV ETL F A RL S + +RVE +I +L L NT +G+ RGVSGGE
Sbjct: 180 LPNLTVRETLTFIAQMRLPKTFSQAQRDKRVEDVIAELRLRQCANTRVGNTYVRGVSGGE 239
Query: 180 RRRVSIGVDIIHGPSLLFLDEPTSGLDSTSALSVIEKLHDIARNGSTVILTIHQPSSRIQ 239
RRRVSIGV ++ P +L LDEPTSGLDS +A +++ L +A+ V++++HQP S I
Sbjct: 240 RRRVSIGVQLLWNPGILILDEPTSGLDSFTAHNLVRTLSRLAKGNRLVLISLHQPRSDIF 299
Query: 240 LLLDHLIILARGQLMFQGSLKDVGHHLNRMGRKIPKGENPIENLIDV 286
L D ++++ G ++ G + + + +G P+ NP + +D+
Sbjct: 300 RLFDLVLLMTSGTPIYLGVAQHMVQYFTSIGYPCPRYSNPADFYVDL 346
Score = 55.1 bits (131), Expect = 7e-07
Identities = 51/265 (19%), Positives = 114/265 (42%), Gaps = 8/265 (3%)
Query: 462 LMRRNFTN-IRRTPELFLSRLMVLTFMGVMMATMFHNPKNTLQGITNRLSFFIFTVCLFF 520
L+RR +N R P LF+ ++ + + L + F+ + F
Sbjct: 423 LIRRQISNDFRDLPTLFIHGAEACLMSLIIGFLYYGHADKPLSFMDMAALLFMIGALIPF 482
Query: 521 FSSNDAVPAFIQERFIFIRETSHNAYRASCYTIASLITHMPFLALQALAYAAIVWFALEL 580
D V ER + E Y A Y A ++ +P + Y +++ L
Sbjct: 483 NVILDVVSKCHSERSLLYYELEDGLYTAGPYFFAKVLGELPEHCAYVIIYGMPIYWLTNL 542
Query: 581 R-GP--FIYFFLVLFISLLSTNSFVVFVSSIVPNYILGYAAVIAFTALFFLFCGYFLSSE 637
R GP F+ F++L++ + + + S+++P + + A F+L G+ ++
Sbjct: 543 RPGPELFLLHFMLLWLVVFCCRTMALAASAMLPTFHMSSFCCNALYNSFYLTAGFMINLN 602
Query: 638 DIPLYWRWMNKVSTMTYPYEGLLMNEYQTN--ETFGSNDGVSITGFDILKSLHIGTEEIK 695
++ + W++K+S + + + GL+ ++ + T N S+ G ++ ++ + + +
Sbjct: 603 NLWIVPAWISKMSFLRWCFSGLMQIQFNGHIYTTQIGNLTFSVPGDAMVTAMDLNSHPLY 662
Query: 696 KRNNVLIMLGWAVLYRILFYIILRF 720
LI++G + + L+Y+ L+F
Sbjct: 663 A--IYLIVIGISCGFLSLYYLSLKF 685
>WHIT_LUCCU (Q05360) White protein
Length = 677
Score = 158 bits (400), Expect = 4e-38
Identities = 95/242 (39%), Positives = 144/242 (59%), Gaps = 5/242 (2%)
Query: 51 LLHDITGYAPKGCITAVMGPSGAGKSTLLDGLAGRIASG---SLKGKVSLDGNSVNASLI 107
L+ ++ G A G + AVMG SGAGK+TLL+ LA R A G S L+G+ V+A +
Sbjct: 101 LIKNVCGVAYPGELLAVMGSSGAGKTTLLNALAFRSARGVQISPSSVRMLNGHPVDAKEM 160
Query: 108 KRTSAYIMQEDRLFPMLTVYETLMFAADFRLG-PLSAVDKRQRVEKLIEQLGLSSSRNTY 166
+ AY+ Q+D LT E L+F A R+ ++ K QRV+++I+ L L +NT
Sbjct: 161 QARCAYVQQDDLFIGSLTAREHLIFQATVRMPRTMTQKQKLQRVDQVIQDLSLIKCQNTI 220
Query: 167 IGDEG-TRGVSGGERRRVSIGVDIIHGPSLLFLDEPTSGLDSTSALSVIEKLHDIARNGS 225
IG G +G+SGGER+R++ + + P LL DEPTSGLDS A SV++ L +++ G
Sbjct: 221 IGVPGRVKGLSGGERKRLAFASEALTDPPLLICDEPTSGLDSFMAASVVQVLKKLSQRGK 280
Query: 226 TVILTIHQPSSRIQLLLDHLIILARGQLMFQGSLKDVGHHLNRMGRKIPKGENPIENLID 285
TVILTIHQPSS + L D ++++A G++ F G+ + + +G + P NP + +
Sbjct: 281 TVILTIHQPSSELFELFDKILLMAEGRVAFLGTPVEAVDFFSFIGAQCPTNYNPADFYVQ 340
Query: 286 VI 287
V+
Sbjct: 341 VL 342
Score = 85.1 bits (209), Expect = 6e-16
Identities = 65/273 (23%), Positives = 125/273 (44%), Gaps = 12/273 (4%)
Query: 462 LMRRNFTNIRRTPELFLSRLMVLTFMGVMMATMFHNPKNTLQGITN-RLSFFIFTVCLFF 520
+M R++ + + P L RL+ T + V++ +F N T G+ N + F+F + F
Sbjct: 407 IMWRSWISTLKEPLLVKVRLIQTTMVAVLIGLIFLNQPMTQVGVMNINGAIFLFLTNMTF 466
Query: 521 FSSNDAVPAFIQERFIFIRETSHNAYRASCYTIASLITHMPFLALQALAYAAIVWFALEL 580
+ + F E +F+RET YR Y + + +P + + AI + + L
Sbjct: 467 QNVFAVINVFTSELPVFMRETRSRLYRCDTYFLGKTLAELPLFLVVPFLFIAIAYPMIGL 526
Query: 581 RGPFIYFFLVLFISLLSTN---SFVVFVSSIVPNYILGYAAVIAFTALFFLFCGYFLSSE 637
R +F L + L N SF +S + + + T F LF G FL+S
Sbjct: 527 RPGITHFLSALALVTLVANVSTSFGYLISCASTSTSMALSVGPPLTIPFLLFGGVFLNSG 586
Query: 638 DIPLYWRWMNKVSTMTYPYEGLLMNEY---QTNE--TFGSNDGVSITGFDILKSLHIGTE 692
+P+Y++W++ S Y EGLL+N++ Q E +N +G L++L+ +
Sbjct: 587 SVPVYFKWLSYFSWFRYANEGLLINQWADVQPGEITCTSTNTTCPSSGXVXLETLNFRDK 646
Query: 693 EIKKRNNVLIMLGWAVLYRILFYIILRFASKNQ 725
+ +++++ +++RI Y+ + +K +
Sbjct: 647 FTFRLYGLILLI---LIFRIAGYVAXKMRTKRK 676
>YPC3_CAEEL (Q11180) Putative ABC transporter C05D10.3 in chromosome
III
Length = 598
Score = 156 bits (395), Expect = 2e-37
Identities = 97/303 (32%), Positives = 169/303 (55%), Gaps = 9/303 (2%)
Query: 50 DLLHDITGYAPKGCITAVMGPSGAGKSTLLDGLAGR-IASGSLKGKVSLDGNSVNASLIK 108
++LH+++G A G + A++G SGAGK+TL++ L R + + ++G + +DG N I+
Sbjct: 8 EILHNVSGMAESGKLLAILGSSGAGKTTLMNVLTSRNLTNLDVQGSILIDGRRANKWKIR 67
Query: 109 RTSAYIMQEDRLFPMLTVYETLMFAADFRLGP--LSAVDKRQRVEKLIEQLGLSSSRNTY 166
SA++ Q D +T E L F A R+G S +++ RVE+++ Q+GL +T
Sbjct: 68 EMSAFVQQHDMFVGTMTAREHLQFMARLRMGDQYYSDHERQLRVEQVLTQMGLKKCADTV 127
Query: 167 IG-DEGTRGVSGGERRRVSIGVDIIHGPSLLFLDEPTSGLDSTSALSVIEKLHDIARNGS 225
IG +G+S GE++R+S +I+ P +LF DEPTSGLD+ A V++ L +A NG
Sbjct: 128 IGIPNQLKGLSCGEKKRLSFASEILTCPKILFCDEPTSGLDAFMAGHVVQALRSLADNGM 187
Query: 226 TVILTIHQPSSRIQLLLDHLIILARGQLMFQGSLKDVGHHLNRMGRKIPKGENPIENLID 285
TVI+TIHQPSS + L +++ ++A G++++ G + G P NP ++LI
Sbjct: 188 TVIITIHQPSSHVYSLFNNVCLMACGRVIYLGPGDQAVPLFEKCGYPCPAYYNPADHLIR 247
Query: 286 VIQEYDQCDFVGVEVLAEFARTGMKPPLLSDM-EEIISYTNSIAPSPSPLHRGSKYEEKS 344
+ D ++ +++ R G L +D+ + +++ N+ + GS EK+
Sbjct: 248 TLAVIDSDRATSMKTISKI-RQGF---LSTDLGQSVLAIGNANKLRAASFVTGSDTSEKT 303
Query: 345 QDF 347
+ F
Sbjct: 304 KTF 306
Score = 80.1 bits (196), Expect = 2e-14
Identities = 72/292 (24%), Positives = 119/292 (40%), Gaps = 20/292 (6%)
Query: 451 FANSYIGETWI----LMRRNFTNIRRTPELFLSRLM-VLTFMGVMMATMFHNPKNTLQGI 505
F Y W L R++ + R P L RL+ +L + F P I
Sbjct: 307 FNQDYNASFWTQFLALFWRSWLTVIRDPNLLSVRLLQILITAFITGIVFFQTPVTPATII 366
Query: 506 TNRLSFFIFTVCLFFFSSNDAVPAFIQERFIFIRETSHNAYRASCYTIASLITHMPFLAL 565
+ F + F VP E I +RE ++ YR S Y +A I +P +
Sbjct: 367 SINGIMFNHIRNMNFMLQFPNVPVITAELPIVLRENANGVYRTSAYFLAKNIAELPQYII 426
Query: 566 QALAYAAIVWFALELRGPFIYFFLVLFISLLSTN---SFVVFVSSIVPNYILGYAAVIAF 622
+ Y IV++ L F + +++L TN S V++I N + + F
Sbjct: 427 LPILYNTIVYWMSGLYPNFWNYCFASLVTILITNVAISISYAVATIFANTDVAMTILPIF 486
Query: 623 TALFFLFCGYFLSSEDIPLYWRWMNKVSTMTYPYEGLLMNEYQT----NETFGSN----- 673
F G+F++ + IP Y++W++ +S Y YE L +NE+ + E F S+
Sbjct: 487 VVPIMAFGGFFITFDAIPSYFKWLSSLSYFKYGYEALAINEWDSIKVIPECFNSSMTAFA 546
Query: 674 -DGVSITGFDILKSLHIGTEEIKKRNNVLIMLGWAVLYRILFYIILRFASKN 724
D G +L+S+ K ++ I+ G + RI+ Y+ L S N
Sbjct: 547 LDSCPKNGHQVLESIDFSASH--KIFDISILFGMFIGIRIIAYVALLIRSYN 596
>ABG8_HUMAN (Q9H221) ATP-binding cassette, sub-family G, member 8
(Sterolin-2)
Length = 673
Score = 155 bits (392), Expect = 4e-37
Identities = 83/227 (36%), Positives = 140/227 (61%), Gaps = 2/227 (0%)
Query: 62 GCITAVMGPSGAGKSTLLDGLAGRIASGSLK-GKVSLDGNSVNASLIKRTSAYIMQEDRL 120
G + A++G SG G+++LLD + GR G +K G++ ++G + L+++ A++ Q ++L
Sbjct: 98 GQMLAIIGSSGCGRASLLDVITGRGHGGKIKSGQIWINGQPSSPQLVRKCVAHVRQHNQL 157
Query: 121 FPMLTVYETLMFAADFRLG-PLSAVDKRQRVEKLIEQLGLSSSRNTYIGDEGTRGVSGGE 179
P LTV ETL F A RL S + +RVE +I +L L +T +G+ RG+SGGE
Sbjct: 158 LPNLTVRETLAFIAQMRLPRTFSQAQRDKRVEDVIAELRLRQCADTRVGNMYVRGLSGGE 217
Query: 180 RRRVSIGVDIIHGPSLLFLDEPTSGLDSTSALSVIEKLHDIARNGSTVILTIHQPSSRIQ 239
RRRVSIGV ++ P +L LDEPTSGLDS +A ++++ L +A+ V++++HQP S I
Sbjct: 218 RRRVSIGVQLLWNPGILILDEPTSGLDSFTAHNLVKTLSRLAKGNRLVLISLHQPRSDIF 277
Query: 240 LLLDHLIILARGQLMFQGSLKDVGHHLNRMGRKIPKGENPIENLIDV 286
L D ++++ G ++ G+ + + + +G P+ NP + +D+
Sbjct: 278 RLFDLVLLMTSGTPIYLGAAQHMVQYFTAIGYPCPRYSNPADFYVDL 324
Score = 53.5 bits (127), Expect = 2e-06
Identities = 40/201 (19%), Positives = 91/201 (44%), Gaps = 7/201 (3%)
Query: 525 DAVPAFIQERFIFIRETSHNAYRASCYTIASLITHMPFLALQALAYAAIVWFALELRG-- 582
D + ER + E Y Y A ++ +P + Y ++ LR
Sbjct: 466 DVISKCYSERAMLYYELEDGLYTTGPYFFAKILGELPEHCAYIIIYGMPTYWLANLRPGL 525
Query: 583 -PFIYFFLVLFISLLSTNSFVVFVSSIVPNYILGYAAVIAFTALFFLFCGYFLSSEDIPL 641
PF+ FL++++ + + ++++P + + A F+L G+ ++ +
Sbjct: 526 QPFLLHFLLVWLVVFCCRIMALAAAALLPTFHMASFFSNALYNSFYLAGGFMINLSSLWT 585
Query: 642 YWRWMNKVSTMTYPYEGLLMNEY--QTNETFGSNDGVSITGFDILKSLHIGTEEIKKRNN 699
W++KVS + + +EGL+ ++ +T + N ++++G IL + + + +
Sbjct: 586 VPAWISKVSFLRWCFEGLMKIQFSRRTYKMPLGNLTIAVSGDKILSVMELDSYPLYA--I 643
Query: 700 VLIMLGWAVLYRILFYIILRF 720
LI++G + + +L+Y+ LRF
Sbjct: 644 YLIVIGLSGGFMVLYYVSLRF 664
>WHIT_ANOAL (Q16928) White protein
Length = 709
Score = 154 bits (390), Expect = 6e-37
Identities = 107/303 (35%), Positives = 161/303 (52%), Gaps = 11/303 (3%)
Query: 30 LTYTVTKKKKVDGKWSNEDVDLLHDITGYAPKGCITAVMGPSGAGKSTLLDGLAGRIASG 89
L + T+++ V K N LL ++TG A G + AVMG SGAGK+TLL+ LA R G
Sbjct: 99 LRHCFTRQRLV--KDFNPRKHLLKNVTGVARSGELLAVMGSSGAGKTTLLNELAFRSPPG 156
Query: 90 ---SLKGKVSLDGNSVNASLIKRTSAYIMQEDRLFPMLTVYETLMFAADFRLG---PLSA 143
S +L+G V A ++ AY+ Q+D P LT E LMF A R+G P +
Sbjct: 157 VKISPNAIRTLNGVPVTAEQMRARCAYVQQDDLFIPSLTTKEHLMFQAMLRMGRDVPATP 216
Query: 144 VDKRQRVEKLIEQLGLSSSRNTYIGDEG-TRGVSGGERRRVSIGVDIIHGPSLLFLDEPT 202
+ K RV++++++L L +T IG G +G+SGGER+R + + + P LL DEPT
Sbjct: 217 I-KMHRVDEVLQELSLVKCADTIIGVAGRVKGLSGGERKRTAFRSETLTDPHLLLCDEPT 275
Query: 203 SGLDSTSALSVIEKLHDIARNGSTVILTIHQPSSRIQLLLDHLIILARGQLMFQGSLKDV 262
S LDS A SV++ L +A G T+ILTIHQPSS + L D ++++A G + F GS
Sbjct: 276 SSLDSFMAQSVLQVLKGMAMKGKTIILTIHQPSSELYCLFDRILLVAEG-VAFLGSPYQS 334
Query: 263 GHHLNRMGRKIPKGENPIENLIDVIQEYDQCDFVGVEVLAEFARTGMKPPLLSDMEEIIS 322
+++G P NP + + ++ + E + + + P+ D+ E S
Sbjct: 335 ADFFSQLGIPCPPNYNPADFYVQMLAIAPNKETECRETIKKICDSFAVSPIARDIIETAS 394
Query: 323 YTN 325
N
Sbjct: 395 QVN 397
Score = 73.6 bits (179), Expect = 2e-12
Identities = 62/281 (22%), Positives = 122/281 (43%), Gaps = 13/281 (4%)
Query: 454 SYIGETWILMRRNFTNIRRTPELFLSRLMVLTFMGVMMATMFHNPKNTLQGITN-RLSFF 512
S+ + + ++ R++ ++ + P L RL+ + ++ +++ G+ N S F
Sbjct: 430 SWWTQFYCILWRSWLSVLKDPMLVKVRLLQTAMVASLIGSIYFGQVLDQDGVMNINGSLF 489
Query: 513 IFTVCLFFFSSNDAVPAFIQERFIFIRETSHNAYRASCYTIASLITHMPFLALQALAYAA 572
+F + F + + F E +F+RE YR Y + I +P + +
Sbjct: 490 LFLTNMTFQNVFAVINVFSAELPVFLREKRSRLYRVDTYFLGKTIAELPLFIAVPFVFTS 549
Query: 573 IVWFALELRGPFIYFFLVLFISLLSTN---SFVVFVSSIVPNYILGYAAVIAFTALFFLF 629
I + + L+ ++ LFI L N SF +S + + + F +F
Sbjct: 550 ITYPMIGLKAAISHYLTTLFIVTLVANVSTSFGYLISCASSSISMALSVGPPVVIPFLIF 609
Query: 630 CGYFLSSEDIPLYWRWMNKVSTMTYPYEGLLMNEYQTNE-----TFGSNDGVSITGFDIL 684
G+FL+S +P Y+++++ +S Y E LL+N++ + +N +G IL
Sbjct: 610 GGFFLNSASVPAYFKYLSYLSWFRYANEALLINQWADHRDGEIGCTRANVTCPASGEIIL 669
Query: 685 KSLHIGTEEIKKRNNVLIMLGWAVLYRI--LFYIILRFASK 723
++ + E+ L L VL+R+ LF + LR SK
Sbjct: 670 ETFNFRVEDFALDIGCLFAL--IVLFRLGALFCLWLRSRSK 708
>ABG5_MOUSE (Q99PE8) ATP-binding cassette, sub-family G, member 5
(Sterolin-1)
Length = 652
Score = 154 bits (390), Expect = 6e-37
Identities = 89/250 (35%), Positives = 141/250 (55%), Gaps = 4/250 (1%)
Query: 38 KKVDGKWSNEDVDLLHDITGYAPKGCITAVMGPSGAGKSTLLDGLAGRIA-SGSLKGKVS 96
K KW D +L D++ Y G I ++G SG+GK+TLLD ++GR+ +G+L+G+V
Sbjct: 59 KSCQQKW---DRQILKDVSLYIESGQIMCILGSSGSGKTTLLDAISGRLRRTGTLEGEVF 115
Query: 97 LDGNSVNASLIKRTSAYIMQEDRLFPMLTVYETLMFAADFRLGPLSAVDKRQRVEKLIEQ 156
++G + + +Y++Q D LTV ETL + A L SA ++VE ++ +
Sbjct: 116 VNGCELRRDQFQDCFSYVLQSDVFLSSLTVRETLRYTAMLALCRSSADFYNKKVEAVMTE 175
Query: 157 LGLSSSRNTYIGDEGTRGVSGGERRRVSIGVDIIHGPSLLFLDEPTSGLDSTSALSVIEK 216
L LS + IG G+S GERRRVSI ++ P ++ LDEPT+GLD +A ++
Sbjct: 176 LSLSHVADQMIGSYNFGGISSGERRRVSIAAQLLQDPKVMMLDEPTTGLDCMTANQIVLL 235
Query: 217 LHDIARNGSTVILTIHQPSSRIQLLLDHLIILARGQLMFQGSLKDVGHHLNRMGRKIPKG 276
L ++AR VI+TIHQP S + D + IL G+L+F G+ +++ N G P+
Sbjct: 236 LAELARRDRIVIVTIHQPRSELFQHFDKIAILTYGELVFCGTPEEMLGFFNNCGYPCPEH 295
Query: 277 ENPIENLIDV 286
NP + +D+
Sbjct: 296 SNPFDFYMDL 305
Score = 43.9 bits (102), Expect = 0.002
Identities = 49/227 (21%), Positives = 102/227 (44%), Gaps = 10/227 (4%)
Query: 457 GETWILMRRNFTNIRRTPELFLSRLMVLTFMGV-MMATMFHNPKNTLQG-ITNRLSFFIF 514
G+ +L+RR N+ R + + RL+ MG+ ++ + NTL+G + +R+
Sbjct: 367 GKLGVLLRRVTRNLMRNKQAVIMRLVQNLIMGLFLIFYLLRVQNNTLKGAVQDRVGLLYQ 426
Query: 515 TV-CLFFFSSNDAVPAFIQERFIFIRETSHNAYRASCYTIASLITHMPFLALQALAYAAI 573
V + +AV F R + +E+ Y +A ++ +PF + + ++++
Sbjct: 427 LVGATPYTGMLNAVNLFPMLRAVSDQESQDGLYHKWQMLLAYVLHVLPFSVIATVIFSSV 486
Query: 574 VWFALELR---GPFIYFFLVLFISLLSTNSFVVFVSSIV--PNYILGYAAVIAFTALFFL 628
++ L L F YF L L + + IV PN + A+++ + L +
Sbjct: 487 CYWTLGLYPEVARFGYFSAALLAPHLIGEFLTLVLLGIVQNPNIVNSIVALLSISGL-LI 545
Query: 629 FCGYFLSSEDIPLYWRWMNKVSTMTYPYEGLLMNE-YQTNETFGSND 674
G+ + +++P+ + + + Y E L++NE Y N T G ++
Sbjct: 546 GSGFIRNIQEMPIPLKILGYFTFQKYCCEILVVNEFYGLNFTCGGSN 592
>ABG5_RAT (Q99PE7) ATP-binding cassette, sub-family G, member 5
(Sterolin-1)
Length = 652
Score = 152 bits (383), Expect = 4e-36
Identities = 88/250 (35%), Positives = 141/250 (56%), Gaps = 4/250 (1%)
Query: 38 KKVDGKWSNEDVDLLHDITGYAPKGCITAVMGPSGAGKSTLLDGLAGRIA-SGSLKGKVS 96
K KW D +L D++ Y G ++G SG+GK+TLLD ++GR+ +G+L+G+V
Sbjct: 59 KSCQQKW---DRKILKDVSLYIESGQTMCILGSSGSGKTTLLDAISGRLRRTGTLEGEVF 115
Query: 97 LDGNSVNASLIKRTSAYIMQEDRLFPMLTVYETLMFAADFRLGPLSAVDKRQRVEKLIEQ 156
++G + + +Y++Q D LTV ETL + A L SA ++VE ++ +
Sbjct: 116 VNGCELRRDQFQDCVSYLLQSDVFLSSLTVRETLRYTAMLALRSSSADFYDKKVEAVLTE 175
Query: 157 LGLSSSRNTYIGDEGTRGVSGGERRRVSIGVDIIHGPSLLFLDEPTSGLDSTSALSVIEK 216
L LS + IG+ G+S GERRRVSI ++ P ++ LDEPT+GLD +A ++
Sbjct: 176 LSLSHVADQMIGNYNFGGISSGERRRVSIAAQLLQDPKVMMLDEPTTGLDCMTANHIVLL 235
Query: 217 LHDIARNGSTVILTIHQPSSRIQLLLDHLIILARGQLMFQGSLKDVGHHLNRMGRKIPKG 276
L ++AR VI+TIHQP S + D + IL G+L+F G+ +++ N G P+
Sbjct: 236 LVELARRNRIVIVTIHQPRSELFHHFDKIAILTYGELVFCGTPEEMLGFFNNCGYPCPEH 295
Query: 277 ENPIENLIDV 286
NP + +D+
Sbjct: 296 SNPFDFYMDL 305
Score = 40.8 bits (94), Expect = 0.013
Identities = 46/224 (20%), Positives = 105/224 (46%), Gaps = 12/224 (5%)
Query: 461 ILMRRNFTNIRRTPELFLSRLMVLTFMGV-MMATMFHNPKNTLQG-ITNRLSFFIFTV-C 517
+L+RR N+ R ++ + RL+ MG+ ++ + N L+G + +R+ V
Sbjct: 371 VLLRRVTRNLMRNKQVVIMRLVQNLIMGLFLIFYLLRVQNNMLKGAVQDRVGLLYQLVGA 430
Query: 518 LFFFSSNDAVPAFIQERFIFIRETSHNAYRASCYTIASLITHMPFLALQALAYAAIVWFA 577
+ +AV F R + +E+ Y+ +A ++ +PF + + ++++ ++
Sbjct: 431 TPYTGMLNAVNLFPMLRAVSDQESQDGLYQKWQMLLAYVLHALPFSIVATVIFSSVCYWT 490
Query: 578 LELRGPFIYFFLVLFISLLSTNSFVVFVSSIV------PNYILGYAAVIAFTALFFLFCG 631
L L P + F +LL+ + F++ ++ PN + A+++ + L + G
Sbjct: 491 LGLY-PEVARFGYFSAALLAPHLIGEFLTLVLLGMVQNPNIVNSIVALLSISGL-LIGSG 548
Query: 632 YFLSSEDIPLYWRWMNKVSTMTYPYEGLLMNE-YQTNETFGSND 674
+ + E++P+ + + + Y E L++NE Y N T G ++
Sbjct: 549 FIRNIEEMPIPLKILGYFTFQKYCCEILVVNEFYGLNFTCGGSN 592
>ABG5_HUMAN (Q9H222) ATP-binding cassette, sub-family G, member 5
(Sterolin-1)
Length = 651
Score = 151 bits (382), Expect = 5e-36
Identities = 83/245 (33%), Positives = 142/245 (57%), Gaps = 4/245 (1%)
Query: 43 KWSNEDVDLLHDITGYAPKGCITAVMGPSGAGKSTLLDGLAGRIA-SGSLKGKVSLDGNS 101
+W+ + +L D++ Y G I ++G SG+GK+TLLD ++GR+ +G+ G+V ++G +
Sbjct: 63 QWTRQ---ILKDVSLYVESGQIMCILGSSGSGKTTLLDAMSGRLGRAGTFLGEVYVNGRA 119
Query: 102 VNASLIKRTSAYIMQEDRLFPMLTVYETLMFAADFRLGPLSAVDKRQRVEKLIEQLGLSS 161
+ + +Y++Q D L LTV ETL + A + + +++VE ++ +L LS
Sbjct: 120 LRREQFQDCFSYVLQSDTLLSSLTVRETLHYTALLAIRRGNPGSFQKKVEAVMAELSLSH 179
Query: 162 SRNTYIGDEGTRGVSGGERRRVSIGVDIIHGPSLLFLDEPTSGLDSTSALSVIEKLHDIA 221
+ IG+ G+S GERRRVSI ++ P ++ DEPT+GLD +A ++ L ++A
Sbjct: 180 VADRLIGNYSLGGISTGERRRVSIAAQLLQDPKVMLFDEPTTGLDCMTANQIVVLLVELA 239
Query: 222 RNGSTVILTIHQPSSRIQLLLDHLIILARGQLMFQGSLKDVGHHLNRMGRKIPKGENPIE 281
R V+LTIHQP S + L D + IL+ G+L+F G+ ++ N G P+ NP +
Sbjct: 240 RRNRIVVLTIHQPRSELFQLFDKIAILSFGELIFCGTPAEMLDFFNDCGYPCPEHSNPFD 299
Query: 282 NLIDV 286
+D+
Sbjct: 300 FYMDL 304
Score = 42.4 bits (98), Expect = 0.004
Identities = 51/228 (22%), Positives = 106/228 (46%), Gaps = 11/228 (4%)
Query: 461 ILMRRNFTNIRRTPELFLSRLMVLTFMGV-MMATMFHNPKNTLQG-ITNRLSF-FIFTVC 517
+L+RR N+ R ++RL+ MG+ ++ + N L+G I +R+ + F
Sbjct: 370 VLLRRVTRNLVRNKLAVITRLLQNLIMGLFLLFFVLRVRSNVLKGAIQDRVGLLYQFVGA 429
Query: 518 LFFFSSNDAVPAFIQERFIFIRETSHNAYRASCYTIASLITHMPFLALQALAYAAIVWFA 577
+ +AV F R + +E+ Y+ +A + +PF + + ++++ ++
Sbjct: 430 TPYTGMLNAVNLFPVLRAVSDQESQDGLYQKWQMMLAYALHVLPFSVVATMIFSSVCYWT 489
Query: 578 LELR---GPFIYFFLVLFISLLSTNSFVVFVSSIV--PNYILGYAAVIAFTALFFLFCGY 632
L L F YF L L + + IV PN + A+++ + + G+
Sbjct: 490 LGLHPEVARFGYFSAALLAPHLIGEFLTLVLLGIVQNPNIVNSVVALLSIAGVL-VGSGF 548
Query: 633 FLSSEDIPLYWRWMNKVSTMTYPYEGLLMNE-YQTNETFGSNDGVSIT 679
+ +++P+ ++ ++ + Y E L++NE Y N T GS++ VS+T
Sbjct: 549 LRNIQEMPIPFKIISYFTFQKYCSEILVVNEFYGLNFTCGSSN-VSVT 595
>WHIT_CERCA (Q17320) White protein
Length = 679
Score = 149 bits (376), Expect = 3e-35
Identities = 93/242 (38%), Positives = 141/242 (57%), Gaps = 5/242 (2%)
Query: 51 LLHDITGYAPKGCITAVMGPSGAGKSTLLDGLAGRIASG---SLKGKVSLDGNSVNASLI 107
LL + +G A G + AVMG SGAGK+TLL+ A R + G S L+G+ V+A +
Sbjct: 103 LLKNDSGVAYPGELLAVMGSSGAGKTTLLNASAFRSSKGVQISPSTIRMLNGHPVDAKEM 162
Query: 108 KRTSAYIMQEDRLFPMLTVYETLMFAADFRLGP-LSAVDKRQRVEKLIEQLGLSSSRNTY 166
+ AY+ Q+D LT E L+F A R+ ++ K QRV+++I+ L L +NT
Sbjct: 163 QARCAYVQQDDLFIGSLTAREHLIFQAMVRMPRHMTQKQKVQRVDQVIQDLSLGKCQNTL 222
Query: 167 IGDEG-TRGVSGGERRRVSIGVDIIHGPSLLFLDEPTSGLDSTSALSVIEKLHDIARNGS 225
IG G +G+SGGER+R++ + + P LL DEPTSGLDS A SV++ L +++ G
Sbjct: 223 IGVPGRVKGLSGGERKRLAFASEALTDPPLLICDEPTSGLDSFMAHSVVQVLKKLSQKGK 282
Query: 226 TVILTIHQPSSRIQLLLDHLIILARGQLMFQGSLKDVGHHLNRMGRKIPKGENPIENLID 285
TVILTIHQPSS + L D ++++A G++ F G+ + + +G P P + +
Sbjct: 283 TVILTIHQPSSELFELFDKILLMAEGRVAFLGTPGEAVDFFSYIGATCPTNYTPADFYVQ 342
Query: 286 VI 287
V+
Sbjct: 343 VL 344
Score = 88.2 bits (217), Expect = 7e-17
Identities = 69/273 (25%), Positives = 125/273 (45%), Gaps = 17/273 (6%)
Query: 465 RNFTNIRRTPELFLSRLMVLTFMGVMMATMFHNPKNTLQGITN-RLSFFIFTVCLFFFSS 523
R++ ++ + P L RL+ T + V++ +F + T G+ N + F+F + F +S
Sbjct: 411 RSWLSVLKEPLLVKVRLLQTTMVAVLIGLIFLGQQLTQVGVMNINGAIFLFLTNMTFQNS 470
Query: 524 NDAVPAFIQERFIFIRETSHNAYRASCYTIASLITHMPFLALQALAYAAIVWFALELRGP 583
+ F E +F+RET YR Y + I +P + + AI + + LR
Sbjct: 471 FATITVFTTELPVFMRETRSRLYRCDTYFLGKTIAELPLFLVVPFLFTAIAYPLIGLRPG 530
Query: 584 FIYFFLVLFISLLSTN---SFVVFVSSIVPNYILGYAAVIAFTALFFLFCGYFLSSEDIP 640
+FF L + L N SF +S + + + F LF G+FL+S +P
Sbjct: 531 VDHFFTALALVTLVANVSTSFGYLISCACSSTSMALSVGPPVIIPFLLFGGFFLNSGSVP 590
Query: 641 LYWRWMNKVSTMTYPYEGLLMNEYQTNETFG-----SNDGVSITGFDILKSLHIGTEEIK 695
+Y++W++ +S Y EGLL+N++ + SN +G IL++L+ ++
Sbjct: 591 VYFKWLSYLSWFRYANEGLLINQWADVKPGEITCTLSNTTCPSSGEVILETLNFSASDLP 650
Query: 696 KRNNVLIMLGWAVL---YRILFYIILRFASKNQ 725
+G A+L +RI YI L ++ +
Sbjct: 651 -----FDFIGLALLIVGFRISAYIALTMRARRK 678
>PDRC_YEAST (Q02785) ATP-dependent permease PDR12
Length = 1511
Score = 147 bits (372), Expect = 7e-35
Identities = 93/245 (37%), Positives = 147/245 (59%), Gaps = 10/245 (4%)
Query: 51 LLHDITGYAPKGCITAVMGPSGAGKSTLLDGLAGRIASGSLKGKVSLDGNSVNASLIKRT 110
LL D+ GY G +TA+MG SGAGK+TLL+ LA RI G + G + ++ + AS R+
Sbjct: 860 LLSDVFGYVKPGKMTALMGESGAGKTTLLNVLAQRINMGVITGDMLVNAKPLPASF-NRS 918
Query: 111 SAYIMQEDRLFPMLTVYETLMFAADFRL-GPLSAVDKRQRVEKLIEQLGLSSSRNTYIGD 169
Y+ Q D L+V E+L FAA+ R + +K + VEK+I LG+ + +G
Sbjct: 919 CGYVAQADNHMAELSVRESLRFAAELRQQSSVPLEEKYEYVEKIITLLGMQNYAEALVGK 978
Query: 170 EGTRGVSGGERRRVSIGVDIIHGPSLL-FLDEPTSGLDSTSALSVIEKLHDIARNGSTVI 228
G RG++ +R+++SIGV+++ PSLL FLDEPTSGLDS SA S+++ + +A +G +++
Sbjct: 979 TG-RGLNVEQRKKLSIGVELVAKPSLLLFLDEPTSGLDSQSAWSIVQFMRALADSGQSIL 1037
Query: 229 LTIHQPSSRIQLLLDHLIILAR-GQLMFQGSLKDVGHHL-----NRMGRKIPKGENPIEN 282
TIHQPS+ + D L++L + G++++ G + L + G K ENP E
Sbjct: 1038 CTIHQPSATLFEQFDRLLLLKKGGKMVYFGDIGPNSETLLKYFERQSGMKCGVSENPAEY 1097
Query: 283 LIDVI 287
+++ I
Sbjct: 1098 ILNCI 1102
Score = 87.0 bits (214), Expect = 2e-16
Identities = 74/253 (29%), Positives = 118/253 (46%), Gaps = 12/253 (4%)
Query: 50 DLLHDITGYAPKGCITAVMGPSGAGKSTLLDGLAGRIAS-GSLKGKVSLDG--NSVNASL 106
+++ + TG G + V+G GAG ST L L+G + ++G+ S DG S S
Sbjct: 162 NIIQNCTGVVESGEMLFVVGRPGAGCSTFLKCLSGETSELVDVQGEFSYDGLDQSEMMSK 221
Query: 107 IKRTSAYIMQEDRLFPMLTVYETLMFAADFRLGPLSAVDK---RQRVEKLIEQ----LGL 159
K Y + D FP +TV ET+ FA + P +DK +Q V+ + + GL
Sbjct: 222 YKGYVIYCPELDFHFPKITVKETIDFALKCKT-PRVRIDKMTRKQYVDNIRDMWCTVFGL 280
Query: 160 SSSRNTYIGDEGTRGVSGGERRRVSIGVDIIHGPSLLFLDEPTSGLDSTSALSVIEKLHD 219
+ T +G++ RGVSGGER+RVS+ S+ D T GLD+++AL + +
Sbjct: 281 RHTYATKVGNDFVRGVSGGERKRVSLVEAQAMNASIYSWDNATRGLDASTALEFAQAIRT 340
Query: 220 IARN-GSTVILTIHQPSSRIQLLLDHLIILARGQLMFQGSLKDVGHHLNRMGRKIPKGEN 278
++ I+ I+Q I L D +L G+ ++ G + RMG P
Sbjct: 341 ATNMVNNSAIVAIYQAGENIYELFDKTTVLYNGRQIYFGPADKAVGYFQRMGWVKPNRMT 400
Query: 279 PIENLIDVIQEYD 291
E L V +++
Sbjct: 401 SAEFLTSVTVDFE 413
Score = 52.8 bits (125), Expect = 3e-06
Identities = 58/288 (20%), Positives = 115/288 (39%), Gaps = 17/288 (5%)
Query: 396 ENKVQKPPSHASPGIYTYSSEI---LPATPTPHSSDYVVDEN-DYLTPTNSSQEHLGPKF 451
E+KV K S Y +SE L T + S + V+E D L + G +
Sbjct: 424 EDKVPKSSSEFEE--YWLNSEDYQELLRTYDDYQSRHPVNETRDRLDVAKKQRLQQGQRE 481
Query: 452 ANSYIGETWI----LMRRNFTNIRRTPELFLSRLMVLTFMGVMMATMFHN----PKNTLQ 503
+ Y+ W M R F ++ L +++ +MFH ++T
Sbjct: 482 NSQYVVNYWTQVYYCMIRGFQRVKGDSTYTKVYLSSFLIKALIIGSMFHKIDDKSQSTTA 541
Query: 504 GITNRLSFFIFTVCLFFFSSNDAVPAFIQERFIFIRETSHNAYRASCYTIASLITHMP-- 561
G +R + + +S + R + ++ S++ Y S ++ +IT P
Sbjct: 542 GAYSRGGMLFYVLLFASVTSLAEIGNSFSSRPVIVKHKSYSMYHLSAESLQEIITEFPTK 601
Query: 562 FLALQALAYAAI-VWFALELRGPFIYFFLVLFISLLSTNSFVVFVSSIVPNYILGYAAVI 620
F+A+ L + F G F + L L T+ FV+++ + + +A
Sbjct: 602 FVAIVILCLITYWIPFMKYEAGAFFQYILYLLTVQQCTSFIFKFVATMSKSGVDAHAVGG 661
Query: 621 AFTALFFLFCGYFLSSEDIPLYWRWMNKVSTMTYPYEGLLMNEYQTNE 668
+ + ++ G+ L ++ + RW++ ++ +TY +E L+ E+ E
Sbjct: 662 LWVLMLCVYAGFVLPIGEMHHWIRWLHFINPLTYAFESLVSTEFHHRE 709
Score = 45.1 bits (105), Expect = 7e-04
Identities = 47/226 (20%), Positives = 93/226 (40%), Gaps = 18/226 (7%)
Query: 447 LGPKFANSYIGETWILMRRNFTNIRRTPEL----FLSRLMVLTFMGVMMATMFHNPKNTL 502
L +FA SY+ + ++RR R+P F + F+G+ + H+ +
Sbjct: 1149 LATRFAASYMTQIKCVLRRTALQFWRSPVYIRAKFFECVACALFVGLSYVGVNHSVGGAI 1208
Query: 503 QGITNRLSFFIFTVCLFFFSSNDAVPAFIQERFIFIRETSHNAYRASCYTIASLITHMPF 562
+ + S F+ + + V A+ +RE + N + S + +
Sbjct: 1209 EAFS---SIFMLLLIALAMINQLHVFAYDSRELYEVREAASNTFHWSVLLLCHAAVENFW 1265
Query: 563 LAL-QALAYAAIVWFA-----LELRGPFIYFFLVLF-ISLLSTNSFVVFVSSIVPNYILG 615
L Q + + W A G F +F++++F + ++ +++++S VP+ +
Sbjct: 1266 STLCQFMCFICYYWPAQFSGRASHAGFFFFFYVLIFPLYFVTYGLWILYMSPDVPSASMI 1325
Query: 616 YAAVIAFTALFFLFCGYFLSSEDIPLYW-RWMNKVSTMTYPYEGLL 660
+ + A LFCG E +P +W R M VS TY + L+
Sbjct: 1326 NSNLFA---AMLLFCGILQPREKMPAFWRRLMYNVSPFTYVVQALV 1368
>SNQ2_YEAST (P32568) SNQ2 protein
Length = 1501
Score = 144 bits (364), Expect = 6e-34
Identities = 93/245 (37%), Positives = 149/245 (59%), Gaps = 11/245 (4%)
Query: 51 LLHDITGYAPKGCITAVMGPSGAGKSTLLDGLAGRIASGSLKGKVSLDGNSVNASLIKRT 110
LL +++GY G +TA+MG SGAGK+TLL+ LA R G + G + ++G ++AS +RT
Sbjct: 871 LLDNVSGYCIPGTMTALMGESGAGKTTLLNTLAQRNV-GIITGDMLVNGRPIDASFERRT 929
Query: 111 SAYIMQEDRLFPMLTVYETLMFAADFRLGP-LSAVDKRQRVEKLIEQLGLSSSRNTYIGD 169
Y+ Q+D LTV E+L F+A R L +K VEK+I LG+ +G+
Sbjct: 930 G-YVQQQDIHIAELTVRESLQFSARMRRPQHLPDSEKMDYVEKIIRVLGMEEYAEALVGE 988
Query: 170 EGTRGVSGGERRRVSIGVDIIHGPSLL-FLDEPTSGLDSTSALSVIEKLHDIARNGSTVI 228
G G++ +R+++SIGV+++ P LL FLDEPTSGLDS S+ ++I+ L +++ G +++
Sbjct: 989 VGC-GLNVEQRKKLSIGVELVAKPDLLLFLDEPTSGLDSQSSWAIIQLLRKLSKAGQSIL 1047
Query: 229 LTIHQPSSRIQLLLDHLIILAR-GQLMFQGSL----KDVGHHLNRMG-RKIPKGENPIEN 282
TIHQPS+ + D L++L + GQ ++ G + + ++ R G RK ENP E
Sbjct: 1048 CTIHQPSATLFEEFDRLLLLRKGGQTVYFGDIGKNSATILNYFERNGARKCDSSENPAEY 1107
Query: 283 LIDVI 287
+++ I
Sbjct: 1108 ILEAI 1112
Score = 93.2 bits (230), Expect = 2e-18
Identities = 85/289 (29%), Positives = 137/289 (46%), Gaps = 16/289 (5%)
Query: 10 TVIDIKHKPVSFTG--GLEFES-LTYTVTKKKKVDGKWSNEDVDLLHDITGYAPKGCITA 66
T+ D+ K V + G F + L +T K + K + ++ ++ A G +
Sbjct: 131 TIEDVSAKGVDASALEGATFGNILCLPLTIFKGIKAKRHQKMRQIISNVNALAEAGEMIL 190
Query: 67 VMGPSGAGKSTLLDGLAGRIA--SGSLKGKVSLDGNSVNASLIKRTSAYIMQEDRL---F 121
V+G GAG S+ L AG I +G + G+V+ DG ++KR A ++ L F
Sbjct: 191 VLGRPGAGCSSFLKVTAGEIDQFAGGVSGEVAYDGIP-QEEMMKRYKADVIYNGELDVHF 249
Query: 122 PMLTVYETLMFAADFRLGPLSA--VDKRQ----RVEKLIEQLGLSSSRNTYIGDEGTRGV 175
P LTV +TL FA + L V K++ R + GL + NT +G++ RGV
Sbjct: 250 PYLTVKQTLDFAIACKTPALRVNNVSKKEYIASRRDLYATIFGLRHTYNTKVGNDFVRGV 309
Query: 176 SGGERRRVSIGVDIIHGPSLLFLDEPTSGLDSTSALSVIEKLHDIAR-NGSTVILTIHQP 234
SGGER+RVSI + S+ D T GLD+++AL + + + ST +TI+Q
Sbjct: 310 SGGERKRVSIAEALAAKGSIYCWDNATRGLDASTALEYAKAIRIMTNLLKSTAFVTIYQA 369
Query: 235 SSRIQLLLDHLIILARGQLMFQGSLKDVGHHLNRMGRKIPKGENPIENL 283
S I D + +L G+ ++ G + + + +MG P + E L
Sbjct: 370 SENIYETFDKVTVLYSGKQIYFGLIHEAKPYFAKMGYLCPPRQATAEFL 418
Score = 52.4 bits (124), Expect = 4e-06
Identities = 48/221 (21%), Positives = 95/221 (42%), Gaps = 15/221 (6%)
Query: 450 KFANSYIGETWILMRRNFTNIRRTPELFLSRLMVLTFMGVMMATMFHNPKNTLQGITNRL 509
K+A SY + ++ R T+ R+ +S++M++ G+ + F N + G+ N +
Sbjct: 1163 KYATSYAYQFRYVLIRTSTSFWRSLNYIMSKMMLMLVGGLYIGFTFFNVGKSYVGLQNAM 1222
Query: 510 SFFIFTVCLFFFSSNDAVPAFIQERFIF-IRETSHNAYRASCYTIASLITHMPFLALQAL 568
++ L + N I R +F +RE+ N + S I ++ +P+ +
Sbjct: 1223 FAAFISIILSAPAMNQIQGRAIASRELFEVRESQSNMFHWSLVLITQYLSELPYHLFFST 1282
Query: 569 AYAAIVWFAL----ELRGPFIYF--FLVLF-ISLLSTNSFVVFVSSIVP--NYILGYAAV 619
+ +F L E +YF + ++F + + ++++S +P N ILG
Sbjct: 1283 IFFVSSYFPLRIFFEASRSAVYFLNYCIMFQLYYVGLGLMILYMSPNLPSANVILGLC-- 1340
Query: 620 IAFTALFFLFCGYFLSSEDIPLYWRWMNKVSTMTYPYEGLL 660
+ FCG +P +W +M K S TY + L+
Sbjct: 1341 ---LSFMLSFCGVTQPVSLMPGFWTFMWKASPYTYFVQNLV 1378
Score = 43.9 bits (102), Expect = 0.002
Identities = 38/214 (17%), Positives = 79/214 (36%), Gaps = 5/214 (2%)
Query: 454 SYIGETWILMRRNFTNIRRTPELFLSRLMVLTFMGVMMATMFHNPKNTLQGITNRLSFFI 513
SY + + +R F I + + + ++F+N ++ G +R
Sbjct: 499 SYWEQVKLCTQRGFQRIYGNKSYTVINVCSAIIQSFITGSLFYNTPSSTSGAFSRGGVLY 558
Query: 514 FTVCLFFFSSNDAVPAFIQERFIFIRETSHNAYRASCYTIASLITHMPFLALQALAYAAI 573
F L ++S + R I + ++ Y S I S + PF + + I
Sbjct: 559 FA--LLYYSLMGLANISFEHRPILQKHKGYSLYHPSAEAIGSTLASFPFRMIGLTCFFII 616
Query: 574 VWFALELR---GPFIYFFLVLFISLLSTNSFVVFVSSIVPNYILGYAAVIAFTALFFLFC 630
++F L G F +L L + + N VSS+ + ++
Sbjct: 617 LFFLSGLHRTAGSFFTIYLFLTMCSEAINGLFEMVSSVCDTLSQANSISGILMMSISMYS 676
Query: 631 GYFLSSEDIPLYWRWMNKVSTMTYPYEGLLMNEY 664
Y + + +++W++ V + Y +E +L E+
Sbjct: 677 TYMIQLPSMHPWFKWISYVLPIRYAFESMLNAEF 710
Database: sprot
Posted date: Nov 25, 2004 10:54 AM
Number of letters in database: 59,974,054
Number of sequences in database: 164,201
Lambda K H
0.321 0.137 0.400
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 84,346,755
Number of Sequences: 164201
Number of extensions: 3687346
Number of successful extensions: 14395
Number of sequences better than 10.0: 994
Number of HSP's better than 10.0 without gapping: 862
Number of HSP's successfully gapped in prelim test: 132
Number of HSP's that attempted gapping in prelim test: 11898
Number of HSP's gapped (non-prelim): 1534
length of query: 727
length of database: 59,974,054
effective HSP length: 118
effective length of query: 609
effective length of database: 40,598,336
effective search space: 24724386624
effective search space used: 24724386624
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 70 (31.6 bits)
Medicago: description of AC126010.8