BLAST2 result
BLASTP 2.2.2 [Dec-14-2001]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= AC126010.6 + phase: 0
(518 letters)
Database: sprot
164,201 sequences; 59,974,054 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
GLYM_PEA (P34899) Serine hydroxymethyltransferase, mitochondrial... 990 0.0
GLYM_SOLTU (P50433) Serine hydroxymethyltransferase, mitochondri... 928 0.0
GLYM_ARATH (Q9SZJ5) Serine hydroxymethyltransferase, mitochondri... 919 0.0
GLYM_FLAPR (P49357) Serine hydroxymethyltransferase 1, mitochond... 918 0.0
GLYN_FLAPR (P49358) Serine hydroxymethyltransferase 2, mitochond... 907 0.0
GLYM_HUMAN (P34897) Serine hydroxymethyltransferase, mitochondri... 577 e-164
GLYM_CANAL (O13425) Serine hydroxymethyltransferase, mitochondri... 575 e-163
GLYD_SCHPO (O13972) Probable serine hydroxymethyltransferase, cy... 570 e-162
GLYC_SCHPO (Q10104) Probable serine hydroxymethyltransferase, cy... 570 e-162
GLYM_NEUCR (Q7S5N8) Putative serine hydroxymethyltransferase, mi... 568 e-162
GLYC_HUMAN (P34896) Serine hydroxymethyltransferase, cytosolic (... 568 e-161
GLYC_CAEEL (P50432) Serine hydroxymethyltransferase (EC 2.1.2.1)... 567 e-161
GLYC_MOUSE (P50431) Serine hydroxymethyltransferase, cytosolic (... 567 e-161
GLYM_RABIT (P14519) Serine hydroxymethyltransferase, mitochondri... 566 e-161
GLYC_CANAL (O13426) Serine hydroxymethyltransferase, cytosolic (... 563 e-160
GLYC_SHEEP (P35623) Serine hydroxymethyltransferase, cytosolic (... 560 e-159
GLYC_RABIT (P07511) Serine hydroxymethyltransferase, cytosolic (... 558 e-159
GLYM_ASHGO (Q758F0) Serine hydroxymethyltransferase, mitochondri... 545 e-155
GLYC_ASHGO (Q75BQ6) Serine hydroxymethyltransferase, cytosolic (... 545 e-154
GLYC_CANGA (Q6FUP6) Serine hydroxymethyltransferase, cytosolic (... 544 e-154
>GLYM_PEA (P34899) Serine hydroxymethyltransferase, mitochondrial
precursor (EC 2.1.2.1) (Serine methylase) (Glycine
hydroxymethyltransferase) (SHMT)
Length = 518
Score = 990 bits (2559), Expect = 0.0
Identities = 494/518 (95%), Positives = 511/518 (98%)
Query: 1 MAMAMALRRLSSSINKSSRPLFSASSVYYKSSLPDEAVYDKENSRVSWPKQLNSSLEEID 60
MAMAMALR+LSSS+NKSSRPLFSASS+YYKSSLPDEAVYDKEN RV+WPKQLNS LE ID
Sbjct: 1 MAMAMALRKLSSSVNKSSRPLFSASSLYYKSSLPDEAVYDKENPRVTWPKQLNSPLEVID 60
Query: 61 PEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSIMTNKYSEGYPGARYYGGNEYID 120
PEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGS+MTNKYSEGYPGARYYGGNEYID
Sbjct: 61 PEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVMTNKYSEGYPGARYYGGNEYID 120
Query: 121 MAETLCQKRALEAFRLDPAKWGVNVQPLSGSPSNFHVYTALLKPHDRIMALDLPHGGHLS 180
MAETLCQKRALEAFRLDPAKWGVNVQPLSGSPSNF VYTALLKPHDRIMALDLPHGGHLS
Sbjct: 121 MAETLCQKRALEAFRLDPAKWGVNVQPLSGSPSNFQVYTALLKPHDRIMALDLPHGGHLS 180
Query: 181 HGYQTDTKKISAVSIFFETMPYRLDESTGYIDYDQLEKSATLFRPKLIVAGASAYARLYD 240
HGYQTDTKKISAVSIFFETMPYRLDESTGYIDYDQLEKSATLFRPKLIVAGASAYARLYD
Sbjct: 181 HGYQTDTKKISAVSIFFETMPYRLDESTGYIDYDQLEKSATLFRPKLIVAGASAYARLYD 240
Query: 241 YARIRKVCDKQKAVMLADMAHISGLVAAGVIPSPFDYADVVTTTTHKSLRGPRGAMIFFR 300
YARIRKVCDKQKAV+LADMAHISGLVAAGVIPSPFDYADVVTTTTHKSLRGPRGAMIFFR
Sbjct: 241 YARIRKVCDKQKAVLLADMAHISGLVAAGVIPSPFDYADVVTTTTHKSLRGPRGAMIFFR 300
Query: 301 KGLKEVNKQGKEVFYDYEDKINQAVFPGLQGGPHNHTITGLAVALKQATTPEYKAYQEQV 360
KGLKEVNKQGKEVFYDYEDKINQAVFPGLQGGPHNHTITGLAVALKQATTPEY+AYQEQV
Sbjct: 301 KGLKEVNKQGKEVFYDYEDKINQAVFPGLQGGPHNHTITGLAVALKQATTPEYRAYQEQV 360
Query: 361 LSNCAKFAQALSEKGYELVSGGTENHLVLVNLKNKGIDGSRVEKVLEAVHIAANKNTVPG 420
LSN +KFA+ALSEKGY+LVSGGTENHLVLVNLKNKGIDGSRVEKVLE VHIAANKNTVPG
Sbjct: 361 LSNSSKFAKALSEKGYDLVSGGTENHLVLVNLKNKGIDGSRVEKVLELVHIAANKNTVPG 420
Query: 421 DVSAMVPGGIRMGTPALTSRGFVEEDFVKVAEYFDASVNLALKIKAESKGTKLKDFVETL 480
DVSAMVPGGIRMGTPALTSRGFVEEDFVKVAEYFDA+V+LALK+KAESKGTKLKDFVE L
Sbjct: 421 DVSAMVPGGIRMGTPALTSRGFVEEDFVKVAEYFDAAVSLALKVKAESKGTKLKDFVEAL 480
Query: 481 QSSSYVQSEISKLRHDVEEFAKQFPTIGFEKSSMKYNK 518
Q+SSYVQSEISKL+HDVEEFAKQFPTIGFEK++MKYNK
Sbjct: 481 QTSSYVQSEISKLKHDVEEFAKQFPTIGFEKATMKYNK 518
>GLYM_SOLTU (P50433) Serine hydroxymethyltransferase, mitochondrial
precursor (EC 2.1.2.1) (Serine methylase) (Glycine
hydroxymethyltransferase) (SHMT)
Length = 518
Score = 928 bits (2399), Expect = 0.0
Identities = 455/516 (88%), Positives = 497/516 (96%)
Query: 1 MAMAMALRRLSSSINKSSRPLFSASSVYYKSSLPDEAVYDKENSRVSWPKQLNSSLEEID 60
MAMA+ALRRLS++++K + L++ S+YY SSLP+EAVYDKE S V+WPKQLN+ LE +D
Sbjct: 1 MAMAIALRRLSATVDKPVKSLYNGGSLYYMSSLPNEAVYDKEKSGVAWPKQLNAPLEVVD 60
Query: 61 PEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSIMTNKYSEGYPGARYYGGNEYID 120
PEIADIIE EKARQWKGLELIPSENFTS+SVMQAVGS+MTNKYSEGYPGARYYGGNEYID
Sbjct: 61 PEIADIIEHEKARQWKGLELIPSENFTSVSVMQAVGSVMTNKYSEGYPGARYYGGNEYID 120
Query: 121 MAETLCQKRALEAFRLDPAKWGVNVQPLSGSPSNFHVYTALLKPHDRIMALDLPHGGHLS 180
MAETLCQKRALEAFRLDPAKWGVNVQPLSGSP+NF VYTALLKPH+RIMALDLPHGGHLS
Sbjct: 121 MAETLCQKRALEAFRLDPAKWGVNVQPLSGSPANFQVYTALLKPHERIMALDLPHGGHLS 180
Query: 181 HGYQTDTKKISAVSIFFETMPYRLDESTGYIDYDQLEKSATLFRPKLIVAGASAYARLYD 240
HGYQTDTKKISAVSIFFETMPYRLDESTGYIDYDQLEKSATLFRPKLIVAGASAYARLYD
Sbjct: 181 HGYQTDTKKISAVSIFFETMPYRLDESTGYIDYDQLEKSATLFRPKLIVAGASAYARLYD 240
Query: 241 YARIRKVCDKQKAVMLADMAHISGLVAAGVIPSPFDYADVVTTTTHKSLRGPRGAMIFFR 300
Y RIRKVC+KQKA++LADMAHISGLVAAGVIPSPFDYADVVTTTTHKSLRGPRGAMIF+R
Sbjct: 241 YDRIRKVCNKQKAILLADMAHISGLVAAGVIPSPFDYADVVTTTTHKSLRGPRGAMIFYR 300
Query: 301 KGLKEVNKQGKEVFYDYEDKINQAVFPGLQGGPHNHTITGLAVALKQATTPEYKAYQEQV 360
KG+KEVNKQGKEVFYDYEDKINQAVFPGLQGGPHNHTITGLAVALKQATTPEY+AYQEQV
Sbjct: 301 KGVKEVNKQGKEVFYDYEDKINQAVFPGLQGGPHNHTITGLAVALKQATTPEYRAYQEQV 360
Query: 361 LSNCAKFAQALSEKGYELVSGGTENHLVLVNLKNKGIDGSRVEKVLEAVHIAANKNTVPG 420
LSN +KFAQAL EKGYELVSGGT+NHLVLVN+KNKGIDGSRVEKVLEAVHIAANKNTVPG
Sbjct: 361 LSNSSKFAQALGEKGYELVSGGTDNHLVLVNMKNKGIDGSRVEKVLEAVHIAANKNTVPG 420
Query: 421 DVSAMVPGGIRMGTPALTSRGFVEEDFVKVAEYFDASVNLALKIKAESKGTKLKDFVETL 480
DVSAMVPGGIRMGTPALTSRGF+EEDFVKVA++FDA+V +A+K+KAE++GTKLKDFV TL
Sbjct: 421 DVSAMVPGGIRMGTPALTSRGFLEEDFVKVADFFDAAVKIAVKVKAETQGTKLKDFVATL 480
Query: 481 QSSSYVQSEISKLRHDVEEFAKQFPTIGFEKSSMKY 516
+SS+ ++SEI+KLRHDVEE+AKQFPTIGFEK +MKY
Sbjct: 481 ESSAPIKSEIAKLRHDVEEYAKQFPTIGFEKETMKY 516
>GLYM_ARATH (Q9SZJ5) Serine hydroxymethyltransferase, mitochondrial
precursor (EC 2.1.2.1) (Serine methylase) (Glycine
hydroxymethyltransferase) (SHMT)
Length = 517
Score = 919 bits (2376), Expect = 0.0
Identities = 458/516 (88%), Positives = 489/516 (94%), Gaps = 1/516 (0%)
Query: 1 MAMAMALRRLSSSINKSSRPLFSASSVYYKSSLPDEAVYDKENSRVSWPKQLNSSLEEID 60
MAMAMALRRLSSSI+K RPL ++S Y SSLP EAV +KE SRV+WPKQLN+ LEE+D
Sbjct: 1 MAMAMALRRLSSSIDKPIRPLIRSTSCYM-SSLPSEAVDEKERSRVTWPKQLNAPLEEVD 59
Query: 61 PEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSIMTNKYSEGYPGARYYGGNEYID 120
PEIADIIE EKARQWKGLELIPSENFTS+SVMQAVGS+MTNKYSEGYPGARYYGGNEYID
Sbjct: 60 PEIADIIEHEKARQWKGLELIPSENFTSVSVMQAVGSVMTNKYSEGYPGARYYGGNEYID 119
Query: 121 MAETLCQKRALEAFRLDPAKWGVNVQPLSGSPSNFHVYTALLKPHDRIMALDLPHGGHLS 180
MAETLCQKRALEAFRLDP KWGVNVQPLSGSP+NFHVYTALLKPH+RIMALDLPHGGHLS
Sbjct: 120 MAETLCQKRALEAFRLDPEKWGVNVQPLSGSPANFHVYTALLKPHERIMALDLPHGGHLS 179
Query: 181 HGYQTDTKKISAVSIFFETMPYRLDESTGYIDYDQLEKSATLFRPKLIVAGASAYARLYD 240
HGYQTDTKKISAVSIFFETMPYRLDESTGYIDYDQ+EKSATLFRPKLIVAGASAYARLYD
Sbjct: 180 HGYQTDTKKISAVSIFFETMPYRLDESTGYIDYDQMEKSATLFRPKLIVAGASAYARLYD 239
Query: 241 YARIRKVCDKQKAVMLADMAHISGLVAAGVIPSPFDYADVVTTTTHKSLRGPRGAMIFFR 300
YARIRKVC+KQKAVMLADMAHISGLVAA VIPSPFDYADVVTTTTHKSLRGPRGAMIFFR
Sbjct: 240 YARIRKVCNKQKAVMLADMAHISGLVAANVIPSPFDYADVVTTTTHKSLRGPRGAMIFFR 299
Query: 301 KGLKEVNKQGKEVFYDYEDKINQAVFPGLQGGPHNHTITGLAVALKQATTPEYKAYQEQV 360
KG+KE+NKQGKEV YD+EDKINQAVFPGLQGGPHNHTITGLAVALKQATT EYKAYQEQV
Sbjct: 300 KGVKEINKQGKEVLYDFEDKINQAVFPGLQGGPHNHTITGLAVALKQATTSEYKAYQEQV 359
Query: 361 LSNCAKFAQALSEKGYELVSGGTENHLVLVNLKNKGIDGSRVEKVLEAVHIAANKNTVPG 420
LSN AKFAQ L E+GYELVSGGT+NHLVLVNLK KGIDGSRVEKVLEAVHIA+NKNTVPG
Sbjct: 360 LSNSAKFAQTLMERGYELVSGGTDNHLVLVNLKPKGIDGSRVEKVLEAVHIASNKNTVPG 419
Query: 421 DVSAMVPGGIRMGTPALTSRGFVEEDFVKVAEYFDASVNLALKIKAESKGTKLKDFVETL 480
DVSAMVPGGIRMGTPALTSRGFVEEDF KVAEYFD +V +ALK+K+E++GTKLKDFV +
Sbjct: 420 DVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALKVKSEAQGTKLKDFVSAM 479
Query: 481 QSSSYVQSEISKLRHDVEEFAKQFPTIGFEKSSMKY 516
+SSS +QSEI+KLRH+VEEFAKQFPTIGFEK +MKY
Sbjct: 480 ESSSTIQSEIAKLRHEVEEFAKQFPTIGFEKETMKY 515
>GLYM_FLAPR (P49357) Serine hydroxymethyltransferase 1,
mitochondrial precursor (EC 2.1.2.1) (Serine methylase)
(Glycine hydroxymethyltransferase) (SHMT)
Length = 517
Score = 918 bits (2372), Expect = 0.0
Identities = 459/516 (88%), Positives = 486/516 (93%), Gaps = 1/516 (0%)
Query: 1 MAMAMALRRLSSSINKSSRPLFSASSVYYKSSLPDEAVYDKENSRVSWPKQLNSSLEEID 60
MAMA+ALRRLSSS +K + LF+ +Y SSLP EAVY+KE V+WPKQLN+ LE +D
Sbjct: 1 MAMALALRRLSSSADKPLQRLFNGGHLYSMSSLPSEAVYEKERPGVTWPKQLNAPLEVVD 60
Query: 61 PEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSIMTNKYSEGYPGARYYGGNEYID 120
PEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGS+MTNKYSEGYPGARYYGGNEYID
Sbjct: 61 PEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVMTNKYSEGYPGARYYGGNEYID 120
Query: 121 MAETLCQKRALEAFRLDPAKWGVNVQPLSGSPSNFHVYTALLKPHDRIMALDLPHGGHLS 180
MAETLCQKRALEAFRLDPAKWGVNVQPLSGSP+NFHVYTALLK HDRIMALDLPHGGHLS
Sbjct: 121 MAETLCQKRALEAFRLDPAKWGVNVQPLSGSPANFHVYTALLKAHDRIMALDLPHGGHLS 180
Query: 181 HGYQTDTKKISAVSIFFETMPYRLDESTGYIDYDQLEKSATLFRPKLIVAGASAYARLYD 240
HGYQTDTKKISAVSIFFETMPYRL+ESTGYIDYDQLEKSATLFRPKLIVAGASAYARLYD
Sbjct: 181 HGYQTDTKKISAVSIFFETMPYRLNESTGYIDYDQLEKSATLFRPKLIVAGASAYARLYD 240
Query: 241 YARIRKVCDKQKAVMLADMAHISGLVAAGVIPSPFDYADVVTTTTHKSLRGPRGAMIFFR 300
YARIRKVCDKQKA+MLADMAHISGLVAAGVIPSPFDYADVVTTTTHKSLRGPRGAMIFFR
Sbjct: 241 YARIRKVCDKQKAIMLADMAHISGLVAAGVIPSPFDYADVVTTTTHKSLRGPRGAMIFFR 300
Query: 301 KGLKEVNKQGKEVFYDYEDKINQAVFPGLQGGPHNHTITGLAVALKQATTPEYKAYQEQV 360
KGLKEVNKQGKEVFYDYEDKINQAVFPGLQGGPHNHTITGLAVALKQATT EYKAYQEQV
Sbjct: 301 KGLKEVNKQGKEVFYDYEDKINQAVFPGLQGGPHNHTITGLAVALKQATTAEYKAYQEQV 360
Query: 361 LSNCAKFAQALSEKGYELVSGGTENHLVLVNLKNKGIDGSRVEKVLEAVHIAANKNTVPG 420
+SN AKFA+ L + GYELVSGGTENHLVLVNLKNKGIDGS+VEKVLEAVHIAANKNTVPG
Sbjct: 361 MSNSAKFAETLVKSGYELVSGGTENHLVLVNLKNKGIDGSKVEKVLEAVHIAANKNTVPG 420
Query: 421 DVSAMVPGGIRMGTPALTSRGFVEEDFVKVAEYFDASVNLALKIKAESKGTKLKDFVETL 480
DVSAMVPGGIRMGTPALTSRGFVEEDF KVA +FD +V LA+KIK E+KGTKLKDFV +
Sbjct: 421 DVSAMVPGGIRMGTPALTSRGFVEEDFAKVAYFFDLAVKLAVKIKGEAKGTKLKDFVTAM 480
Query: 481 QSSSYVQSEISKLRHDVEEFAKQFPTIGFEKSSMKY 516
+SS+ +QSEISKLRHDVEE+AKQFPTIGFEK +MKY
Sbjct: 481 ESSA-IQSEISKLRHDVEEYAKQFPTIGFEKETMKY 515
>GLYN_FLAPR (P49358) Serine hydroxymethyltransferase 2,
mitochondrial precursor (EC 2.1.2.1) (Serine methylase)
(Glycine hydroxymethyltransferase) (SHMT)
Length = 517
Score = 907 bits (2344), Expect = 0.0
Identities = 457/516 (88%), Positives = 481/516 (92%), Gaps = 1/516 (0%)
Query: 1 MAMAMALRRLSSSINKSSRPLFSASSVYYKSSLPDEAVYDKENSRVSWPKQLNSSLEEID 60
MAMA ALRRLSSS NK + LF+ +Y SSLP EAVY+KE V+WPKQLN+ LE D
Sbjct: 1 MAMASALRRLSSSSNKPLQRLFNGGHLYSMSSLPSEAVYEKERPGVTWPKQLNAPLEVGD 60
Query: 61 PEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSIMTNKYSEGYPGARYYGGNEYID 120
PEIADIIELEKARQWKGLELI SENFTSLSVMQAVGS+MTNKYSEGYPGARYYGGNEYID
Sbjct: 61 PEIADIIELEKARQWKGLELILSENFTSLSVMQAVGSVMTNKYSEGYPGARYYGGNEYID 120
Query: 121 MAETLCQKRALEAFRLDPAKWGVNVQPLSGSPSNFHVYTALLKPHDRIMALDLPHGGHLS 180
MAETLCQKRALEAFRLD AKWGVNVQPLSGSP+NFHVYTALLK HDRIMALDLPHGGHLS
Sbjct: 121 MAETLCQKRALEAFRLDAAKWGVNVQPLSGSPANFHVYTALLKAHDRIMALDLPHGGHLS 180
Query: 181 HGYQTDTKKISAVSIFFETMPYRLDESTGYIDYDQLEKSATLFRPKLIVAGASAYARLYD 240
HGYQTDTKKISAVSIFFETMPYRL+ESTGYIDYDQLEKSATLFRPKLIVAGASAYARLYD
Sbjct: 181 HGYQTDTKKISAVSIFFETMPYRLNESTGYIDYDQLEKSATLFRPKLIVAGASAYARLYD 240
Query: 241 YARIRKVCDKQKAVMLADMAHISGLVAAGVIPSPFDYADVVTTTTHKSLRGPRGAMIFFR 300
YARIRKVCDKQKA++LADMAHISGLVAAGVIPSPFDYADVVTTTTHKSLRGPRGAMIFFR
Sbjct: 241 YARIRKVCDKQKAILLADMAHISGLVAAGVIPSPFDYADVVTTTTHKSLRGPRGAMIFFR 300
Query: 301 KGLKEVNKQGKEVFYDYEDKINQAVFPGLQGGPHNHTITGLAVALKQATTPEYKAYQEQV 360
KG+KEVNKQGKEV YDYEDKINQAVFPGLQGGPHNHTITGLAVALKQATT EYKAYQEQV
Sbjct: 301 KGVKEVNKQGKEVLYDYEDKINQAVFPGLQGGPHNHTITGLAVALKQATTAEYKAYQEQV 360
Query: 361 LSNCAKFAQALSEKGYELVSGGTENHLVLVNLKNKGIDGSRVEKVLEAVHIAANKNTVPG 420
+SNCAKFA+ L + GYELVSGGTENHLVLVNLKNKGIDGSRVEKVLEAVHIAANKNTVPG
Sbjct: 361 MSNCAKFAETLVKSGYELVSGGTENHLVLVNLKNKGIDGSRVEKVLEAVHIAANKNTVPG 420
Query: 421 DVSAMVPGGIRMGTPALTSRGFVEEDFVKVAEYFDASVNLALKIKAESKGTKLKDFVETL 480
DVSAMVPGGIRMGTPALTSRGFVEEDF KVA FD +V LA+KIK E++GTKLKDFV +
Sbjct: 421 DVSAMVPGGIRMGTPALTSRGFVEEDFAKVAYLFDLAVKLAVKIKGEAQGTKLKDFVAAM 480
Query: 481 QSSSYVQSEISKLRHDVEEFAKQFPTIGFEKSSMKY 516
QSS++ QSEISKLRHDVEE+AKQFPTIGFEK +MKY
Sbjct: 481 QSSAF-QSEISKLRHDVEEYAKQFPTIGFEKETMKY 515
>GLYM_HUMAN (P34897) Serine hydroxymethyltransferase, mitochondrial
precursor (EC 2.1.2.1) (Serine methylase) (Glycine
hydroxymethyltransferase) (SHMT)
Length = 504
Score = 577 bits (1488), Expect = e-164
Identities = 286/458 (62%), Positives = 355/458 (77%), Gaps = 3/458 (0%)
Query: 55 SLEEIDPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSIMTNKYSEGYPGARYYG 114
SL + DPE+ ++++ EK RQ +GLELI SENF S + ++A+GS + NKYSEGYPG RYYG
Sbjct: 48 SLSDSDPEMWELLQREKDRQCRGLELIASENFCSRAALEALGSCLNNKYSEGYPGKRYYG 107
Query: 115 GNEYIDMAETLCQKRALEAFRLDPAKWGVNVQPLSGSPSNFHVYTALLKPHDRIMALDLP 174
G E +D E LCQ+RALEAF LDPA+WGVNVQP SGSP+N VYTALL+PHDRIM LDLP
Sbjct: 108 GAEVVDEIELLCQRRALEAFDLDPAQWGVNVQPYSGSPANLAVYTALLQPHDRIMGLDLP 167
Query: 175 HGGHLSHGYQTDTKKISAVSIFFETMPYRLDESTGYIDYDQLEKSATLFRPKLIVAGASA 234
GGHL+HGY +D K+ISA SIFFE+MPY+L+ TG IDY+QL +A LFRP+LI+AG SA
Sbjct: 168 DGGHLTHGYMSDVKRISATSIFFESMPYKLNPKTGLIDYNQLALTARLFRPRLIIAGTSA 227
Query: 235 YARLYDYARIRKVCDKQKAVMLADMAHISGLVAAGVIPSPFDYADVVTTTTHKSLRGPRG 294
YARL DYAR+R+VCD+ KA +LADMAHISGLVAA VIPSPF +AD+VTTTTHK+LRG R
Sbjct: 228 YARLIDYARMREVCDEVKAHLLADMAHISGLVAAKVIPSPFKHADIVTTTTHKTLRGARS 287
Query: 295 AMIFFRKGLKEVN-KQGKEVFYDYEDKINQAVFPGLQGGPHNHTITGLAVALKQATTPEY 353
+IF+RKG+K V+ K G+E+ Y +ED+IN AVFP LQGGPHNH I +AVALKQA TP +
Sbjct: 288 GLIFYRKGVKAVDPKTGREIPYTFEDRINFAVFPSLQGGPHNHAIAAVAVALKQACTPMF 347
Query: 354 KAYQEQVLSNCAKFAQALSEKGYELVSGGTENHLVLVNLKNKGIDGSRVEKVLEAVHIAA 413
+ Y QVL N A AL E+GY LVSGGT+NHLVLV+L+ KG+DG+R E+VLE V I A
Sbjct: 348 REYSLQVLKNARAMADALLERGYSLVSGGTDNHLVLVDLRPKGLDGARAERVLELVSITA 407
Query: 414 NKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFVKVAEYFDASVNLALKIKAESKGTKL 473
NKNT PGD SA+ PGG+R+G PALTSR F E+DF +V ++ D VN+ L++K SK KL
Sbjct: 408 NKNTCPGDRSAITPGGLRLGAPALTSRQFREDDFRRVVDFIDEGVNIGLEVK--SKTAKL 465
Query: 474 KDFVETLQSSSYVQSEISKLRHDVEEFAKQFPTIGFEK 511
+DF L S ++ LR VE+FA+ FP GF++
Sbjct: 466 QDFKSFLLKDSETSQRLANLRQRVEQFARAFPMPGFDE 503
>GLYM_CANAL (O13425) Serine hydroxymethyltransferase, mitochondrial
precursor (EC 2.1.2.1) (Serine methylase) (Glycine
hydroxymethyltransferase) (SHMT)
Length = 493
Score = 575 bits (1482), Expect = e-163
Identities = 278/457 (60%), Positives = 361/457 (78%)
Query: 52 LNSSLEEIDPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSIMTNKYSEGYPGAR 111
++ S++++DPE+ADI+ E+ RQ + LIPSENFTS +VM +GS M NKYSEGYPG R
Sbjct: 35 ISKSVQDVDPEMADILNQERTRQKNSITLIPSENFTSKAVMDLLGSEMQNKYSEGYPGER 94
Query: 112 YYGGNEYIDMAETLCQKRALEAFRLDPAKWGVNVQPLSGSPSNFHVYTALLKPHDRIMAL 171
YYGGNE ID AE LCQKRALEAF LDP++WGVNVQPLSG+P+N + Y+A+L+ DRIM L
Sbjct: 95 YYGGNEIIDKAEALCQKRALEAFGLDPSQWGVNVQPLSGAPANLYAYSAILEVGDRIMGL 154
Query: 172 DLPHGGHLSHGYQTDTKKISAVSIFFETMPYRLDESTGYIDYDQLEKSATLFRPKLIVAG 231
DLPHGGHLSHGYQT T KIS +S +F+TMPYRL+E TG IDYD LEK+A LFRPK+IVAG
Sbjct: 155 DLPHGGHLSHGYQTKTTKISYISKYFQTMPYRLNEETGIIDYDTLEKNAQLFRPKVIVAG 214
Query: 232 ASAYARLYDYARIRKVCDKQKAVMLADMAHISGLVAAGVIPSPFDYADVVTTTTHKSLRG 291
ASAY+R+ DY R+R++ + A +L+DMAHISGLV+A V SPF Y+D+VTTTTHKSLRG
Sbjct: 215 ASAYSRVIDYKRMRQLSIRLGAYLLSDMAHISGLVSAVVTDSPFPYSDIVTTTTHKSLRG 274
Query: 292 PRGAMIFFRKGLKEVNKQGKEVFYDYEDKINQAVFPGLQGGPHNHTITGLAVALKQATTP 351
PRGAMIFFRKG+++V +GKE+ Y+ E KIN VFPG QGGPHNHTI+ LAVALKQ T P
Sbjct: 275 PRGAMIFFRKGIRKVTTKGKEIPYELERKINFLVFPGHQGGPHNHTISALAVALKQCTEP 334
Query: 352 EYKAYQEQVLSNCAKFAQALSEKGYELVSGGTENHLVLVNLKNKGIDGSRVEKVLEAVHI 411
EY YQ++V+SN FA AL KG++LVS GT+ HL+LV+L+++ IDG+RVE VLE +I
Sbjct: 335 EYVKYQQEVVSNAKHFADALVSKGFKLVSDGTDTHLILVDLRSRNIDGARVEAVLERANI 394
Query: 412 AANKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFVKVAEYFDASVNLALKIKAESKGT 471
AANKNTVPGDVSA+ P G+R+GTPA+T+RGF E+F KVAE+ D +VN+A+++KA+ +G
Sbjct: 395 AANKNTVPGDVSALFPSGLRVGTPAMTTRGFGPEEFDKVAEFIDQAVNIAIELKAQEQGK 454
Query: 472 KLKDFVETLQSSSYVQSEISKLRHDVEEFAKQFPTIG 508
K+ + + + + ++ +L +V + ++P G
Sbjct: 455 VPKELLASFKKLADESDKVKQLDKEVVSWVSKYPVPG 491
>GLYD_SCHPO (O13972) Probable serine hydroxymethyltransferase,
cytosolic (EC 2.1.2.1) (Serine methylase) (Glycine
hydroxymethyltransferase) (SHMT)
Length = 467
Score = 570 bits (1469), Expect = e-162
Identities = 278/452 (61%), Positives = 347/452 (76%), Gaps = 3/452 (0%)
Query: 56 LEEIDPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSIMTNKYSEGYPGARYYGG 115
L+E DP +A+I+ E RQ + LI SENFTS +VM A+GS+M+NKYSEGYPGARYYGG
Sbjct: 12 LKEQDPTVAEIMRHEADRQRSSVVLIASENFTSRAVMDALGSVMSNKYSEGYPGARYYGG 71
Query: 116 NEYIDMAETLCQKRALEAFRLDPAKWGVNVQPLSGSPSNFHVYTALLKPHDRIMALDLPH 175
N++ID ETLCQ+RAL AF LDPAKWGVNVQ LSGSP+N VY A++ PH R+M LDLP
Sbjct: 72 NKFIDQIETLCQERALAAFNLDPAKWGVNVQCLSGSPANMQVYQAIMPPHGRLMGLDLPS 131
Query: 176 GGHLSHGYQTDTKKISAVSIFFETMPYRLDESTGYIDYDQLEKSATLFRPKLIVAGASAY 235
GGHLSHGYQTDTKKISAVS +FE+MPYR+D +TG IDYD LE A LFRPK++VAG SAY
Sbjct: 132 GGHLSHGYQTDTKKISAVSTYFESMPYRVDPNTGLIDYDMLEHDAQLFRPKILVAGTSAY 191
Query: 236 ARLYDYARIRKVCDKQKAVMLADMAHISGLVAAGVIPSPFDYADVVTTTTHKSLRGPRGA 295
RL DYAR+R++ D A ++ DMAHISGLV+AGVIPSPF+YADVVTTTTHKSLRGPRGA
Sbjct: 192 CRLIDYARMRQIADSVNAYLVVDMAHISGLVSAGVIPSPFEYADVVTTTTHKSLRGPRGA 251
Query: 296 MIFFRKGLKEVNKQGKEVFYDYEDKINQAVFPGLQGGPHNHTITGLAVALKQATTPEYKA 355
MIFFR+GL++ +K+G ++YD EDKIN +VFPG QGGPHNHTIT LAVALKQ P YK
Sbjct: 252 MIFFRRGLRKHDKKGNPIYYDLEDKINFSVFPGHQGGPHNHTITALAVALKQCQEPAYKE 311
Query: 356 YQEQVLSNCAKFAQALSEKGYELVSGGTENHLVLVNLKNKGIDGSRVEKVLEAVHIAANK 415
YQ QV+ N + ++GY+L + GT++H+VLV++K+KG+DG+R E+VLE ++I NK
Sbjct: 312 YQAQVVKNAKVCEEEFKKRGYKLAADGTDSHMVLVDVKSKGVDGARAERVLELINIVTNK 371
Query: 416 NTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFVKVAEYFDASVNLALKIKAE--SKGTKL 473
NTVP D SA P GIR+GTPA+T+RGF E+DFV+V +Y D ++ A ++ E KL
Sbjct: 372 NTVPSDKSAFSPSGIRVGTPAMTTRGFKEQDFVRVVDYIDRALTFAANLQKELPKDANKL 431
Query: 474 KDFVETLQSSSYVQSEISKLRHDVEEFAKQFP 505
KDF L E+ +L+ +V E+A FP
Sbjct: 432 KDFKAKLGEGEQ-YPELVQLQKEVAEWASSFP 462
>GLYC_SCHPO (Q10104) Probable serine hydroxymethyltransferase,
cytosolic (EC 2.1.2.1) (Serine methylase) (Glycine
hydroxymethyltransferase) (SHMT)
Length = 472
Score = 570 bits (1469), Expect = e-162
Identities = 289/458 (63%), Positives = 352/458 (76%), Gaps = 4/458 (0%)
Query: 50 KQLNSSLEEIDPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSIMTNKYSEGYPG 109
K L + L E DP + I+E EK+RQ + + LI SENFTS +VM A+GSIM NKYSEGYPG
Sbjct: 12 KLLKAPLAECDPTVYKILESEKSRQKESIALIASENFTSRAVMDALGSIMQNKYSEGYPG 71
Query: 110 ARYYGGNEYIDMAETLCQKRALEAFRLDPAKWGVNVQPLSGSPSNFHVYTALLKPHDRIM 169
ARYYGGNE+ID AE LCQ RALEAF LD KWGVNVQP SGSP+N Y A++KPHDR+M
Sbjct: 72 ARYYGGNEFIDQAERLCQTRALEAFHLDGEKWGVNVQPHSGSPANLQAYQAVMKPHDRLM 131
Query: 170 ALDLPHGGHLSHGYQTDTKKISAVSIFFETMPYRLDESTGYIDYDQLEKSATLFRPKLIV 229
LDLPHGGHLSHG+ T K ISAVS +F TMPY +++ TG IDYD LEK+A FRPK+IV
Sbjct: 132 GLDLPHGGHLSHGFSTPQKAISAVSTYFSTMPYNVNKETGIIDYDSLEKAAIQFRPKVIV 191
Query: 230 AGASAYARLYDYARIRKVCDKQKAVMLADMAHISGLVAAGVIPSPFDYADVVTTTTHKSL 289
AGASAYARL DY R+RK+ + A +L DMAHISGLVAAGVIPSPF+YAD+VTTTTHKSL
Sbjct: 192 AGASAYARLVDYKRMRKITEMCNAYLLCDMAHISGLVAAGVIPSPFEYADIVTTTTHKSL 251
Query: 290 RGPRGAMIFFRKGLKEVNKQGKEVFYDYEDKINQAVFPGLQGGPHNHTITGLAVALKQAT 349
RGPRGAMIF+RKG + +K+G + Y+ EDKIN +VFPG QGGPHNHTIT LAVAL QA
Sbjct: 252 RGPRGAMIFYRKGTRSHDKRGNPILYELEDKINFSVFPGHQGGPHNHTITALAVALGQAK 311
Query: 350 TPEYKAYQEQVLSNCAKFAQALSEKGYELVSGGTENHLVLVNLKNKGIDGSRVEKVLEAV 409
TPE+ YQ+ VLSN A A +GY+LVSGGT+ HLVLV+L +KG+DG+RVE++LE V
Sbjct: 312 TPEFYQYQKDVLSNAKAMANAFITRGYKLVSGGTDTHLVLVDLTDKGVDGARVERILELV 371
Query: 410 HIAANKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFVKVAEYFDASVNLALKIK--AE 467
+I+ANKNTVPGD SA++P G+R+GTPA T+RGF E+DF +V E D V+L KI A
Sbjct: 372 NISANKNTVPGDKSALIPRGLRLGTPACTTRGFDEKDFERVVELIDEVVSLTKKINEAAL 431
Query: 468 SKG-TKLKDFVETLQSSSYVQSEISKLRHDVEEFAKQF 504
+G +K +DF + S SEI+KL+ +V +A +F
Sbjct: 432 KEGKSKFRDFKAYVGDGSKF-SEIAKLKKEVITWAGKF 468
>GLYM_NEUCR (Q7S5N8) Putative serine hydroxymethyltransferase,
mitochondrial precursor (EC 2.1.2.1) (Serine methylase)
(Glycine hydroxymethyltransferase) (SHMT)
Length = 527
Score = 568 bits (1465), Expect = e-162
Identities = 285/476 (59%), Positives = 359/476 (74%), Gaps = 24/476 (5%)
Query: 47 SWPKQLNSSLEEIDPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSIMTNKYSEG 106
SW + +SS+ D + EK RQ + + LIPSENFTS +V+ A+GS M NKYSEG
Sbjct: 52 SWTRFSSSSIAN------DNQQKEKQRQKQFINLIPSENFTSQAVLDALGSPMQNKYSEG 105
Query: 107 YPGARYYGGNEYIDMAETLCQKRALEAFRLDPAKWGVNVQPLSGSPSNFHVYTALLKPHD 166
YPGARYYGGNE+ID +E LCQ RALE F LDP +WGVNVQ LSG+P+N +VY+AL+ HD
Sbjct: 106 YPGARYYGGNEFIDASERLCQDRALETFGLDPKEWGVNVQALSGAPANLYVYSALMDTHD 165
Query: 167 RIMALDLPHGGHLSHGYQTDTKKISAVSIFFETMPYRLDESTGYIDYDQLEKSATLFRPK 226
R+M LDLPHGGHLSHGYQT TKKIS +S +FET+PYRLDE TGYIDY++LE+ A +RPK
Sbjct: 166 RLMGLDLPHGGHLSHGYQTPTKKISFISKYFETLPYRLDEKTGYIDYNKLEELAITYRPK 225
Query: 227 LIVAGASAYARLYDYARIRKVCDKQKAVMLADMAHISGLVAAGVIPSPFDYADVVTTTTH 286
+IVAGASAY+RL DYAR+R++CDK A ++ADMAHISGLVAA V+P PF +AD+VTTT+H
Sbjct: 226 IIVAGASAYSRLIDYARLREICDKVNAYLMADMAHISGLVAAKVMPGPFTHADIVTTTSH 285
Query: 287 KSLRGPRGAMIFFRKGLKEVNKQGKEVFYDYEDKINQAVFPGLQGGPHNHTITGLAVALK 346
KSLRGPRGAMIFFR+G++ NK+G+E Y+ E IN +VFPG QGGPHNHTI LAVALK
Sbjct: 286 KSLRGPRGAMIFFRRGVRRTNKKGEEELYNLETPINASVFPGHQGGPHNHTIAALAVALK 345
Query: 347 QATTPEYKAYQEQVLSNCAKFAQALSEK------GYELVSGGTENHLVLVNLKNKGIDGS 400
QA TPE++AYQ QVL+N A L E GY +VSGGT+NHLVL++LK +GIDGS
Sbjct: 346 QAQTPEFRAYQSQVLANATALAARLGEPKDKNGLGYTIVSGGTDNHLVLIDLKPQGIDGS 405
Query: 401 RVEKVLEAVHIAANKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFVKVAEYFDASVNL 460
RVE+VLE V +AANKNTVPGD SA+ PGG+R+GTPA+T+RGF EEDF +VA+ D +V +
Sbjct: 406 RVERVLELVGVAANKNTVPGDKSALTPGGLRIGTPAMTTRGFTEEDFARVADIIDRAVTI 465
Query: 461 ALKIKAESK-----------GTKLKDFVETLQSSSYVQSEISKLRHDVEEFAKQFP 505
A++I +K ++K F++ L + EI +LR +VE + +P
Sbjct: 466 AVRINKAAKEDAVKKGNEKAANRVKTFMDYL-GNGETDPEIVQLRSEVESWVGTYP 520
>GLYC_HUMAN (P34896) Serine hydroxymethyltransferase, cytosolic (EC
2.1.2.1) (Serine methylase) (Glycine
hydroxymethyltransferase) (SHMT)
Length = 483
Score = 568 bits (1464), Expect = e-161
Identities = 281/464 (60%), Positives = 356/464 (76%), Gaps = 3/464 (0%)
Query: 47 SWPKQLNSSLEEIDPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSIMTNKYSEG 106
S K L L++ D E+ +II+ E RQ GLELI SENF S +V++A+GS + NKYSEG
Sbjct: 17 SHDKMLAQPLKDSDVEVYNIIKKESNRQRVGLELIASENFASRAVLEALGSCLNNKYSEG 76
Query: 107 YPGARYYGGNEYIDMAETLCQKRALEAFRLDPAKWGVNVQPLSGSPSNFHVYTALLKPHD 166
YPG RYYGG E+ID ETLCQKRAL+A++LDP WGVNVQP SGSP+NF VYTAL++PH
Sbjct: 77 YPGQRYYGGTEFIDELETLCQKRALQAYKLDPQCWGVNVQPYSGSPANFAVYTALVEPHG 136
Query: 167 RIMALDLPHGGHLSHGYQTDTKKISAVSIFFETMPYRLDESTGYIDYDQLEKSATLFRPK 226
RIM LDLP GGHL+HG+ TD KKISA SIFFE+MPY+++ TGYI+YDQLE++A LF PK
Sbjct: 137 RIMGLDLPDGGHLTHGFMTDKKKISATSIFFESMPYKVNPDTGYINYDQLEENARLFHPK 196
Query: 227 LIVAGASAYARLYDYARIRKVCDKQKAVMLADMAHISGLVAAGVIPSPFDYADVVTTTTH 286
LI+AG S Y+R +YAR+RK+ D+ A ++ADMAHISGLVAAGV+PSPF++ VVTTTTH
Sbjct: 197 LIIAGTSCYSRNLEYARLRKIADENGAYLMADMAHISGLVAAGVVPSPFEHCHVVTTTTH 256
Query: 287 KSLRGPRGAMIFFRKGLKEVN-KQGKEVFYDYEDKINQAVFPGLQGGPHNHTITGLAVAL 345
K+LRG R MIF+RKG+K V+ K GKE+ Y+ E IN AVFPGLQGGPHNH I G+AVAL
Sbjct: 257 KTLRGCRAGMIFYRKGVKSVDPKTGKEILYNLESLINSAVFPGLQGGPHNHAIAGVAVAL 316
Query: 346 KQATTPEYKAYQEQVLSNCAKFAQALSEKGYELVSGGTENHLVLVNLKNKGIDGSRVEKV 405
KQA T E+K YQ QV++NC ++AL+E GY++V+GG++NHL+LV+L++KG DG R EKV
Sbjct: 317 KQAMTLEFKVYQHQVVANCRALSEALTELGYKIVTGGSDNHLILVDLRSKGTDGGRAEKV 376
Query: 406 LEAVHIAANKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFVKVAEYFDASVNLALKIK 465
LEA IA NKNT PGD SA+ P G+R+GTPALTSRG +E+DF KVA + + L L+I+
Sbjct: 377 LEACSIACNKNTCPGDRSALRPSGLRLGTPALTSRGLLEKDFQKVAHFIHRGIELTLQIQ 436
Query: 466 AES-KGTKLKDFVETLQSSSYVQSEISKLRHDVEEFAKQFPTIG 508
+++ LK+F E L Y Q+ + LR +VE FA FP G
Sbjct: 437 SDTGVRATLKEFKERLAGDKY-QAAVQALREEVESFASLFPLPG 479
>GLYC_CAEEL (P50432) Serine hydroxymethyltransferase (EC 2.1.2.1)
(Serine methylase) (Glycine hydroxymethyltransferase)
(SHMT) (Glycosylation related 1)
Length = 507
Score = 567 bits (1462), Expect = e-161
Identities = 275/455 (60%), Positives = 350/455 (76%), Gaps = 1/455 (0%)
Query: 56 LEEIDPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSIMTNKYSEGYPGARYYGG 115
+E++DPE+ DI++ EK RQ +GLELI SENFTS +VM A+GS M NKYSEGYPGARYYGG
Sbjct: 52 VEKVDPEVFDIMKNEKKRQRRGLELIASENFTSKAVMDALGSAMCNKYSEGYPGARYYGG 111
Query: 116 NEYIDMAETLCQKRALEAFRLDPAKWGVNVQPLSGSPSNFHVYTALLKPHDRIMALDLPH 175
NE+ID E LCQKRALE F LDPAKWGVNVQPLSGSP+NF VYTA++ + RIM LDLP
Sbjct: 112 NEFIDQMELLCQKRALEVFGLDPAKWGVNVQPLSGSPANFAVYTAIVGSNGRIMGLDLPD 171
Query: 176 GGHLSHGYQTDTKKISAVSIFFETMPYRLDESTGYIDYDQLEKSATLFRPKLIVAGASAY 235
GGHL+HG+ T +K+SA S FF+++PY++D +TG IDYD+LE++A LFRPK I+AG S Y
Sbjct: 172 GGHLTHGFFTPARKVSATSEFFQSLPYKVDPTTGLIDYDKLEQNAMLFRPKAIIAGVSCY 231
Query: 236 ARLYDYARIRKVCDKQKAVMLADMAHISGLVAAGVIPSPFDYADVVTTTTHKSLRGPRGA 295
AR DY R RK+ K A +++DMAHISGLVAAG+IPSPF+Y+DVVTTTTHKSLRGPRGA
Sbjct: 232 ARHLDYERFRKIATKAGAYLMSDMAHISGLVAAGLIPSPFEYSDVVTTTTHKSLRGPRGA 291
Query: 296 MIFFRKGLKEVNKQGKEVFYDYEDKINQAVFPGLQGGPHNHTITGLAVALKQATTPEYKA 355
+IF+RKG++ N +G + YD E+KIN AVFPGLQGGPHNHTI G+AVAL+Q + ++
Sbjct: 292 LIFYRKGVRSTNAKGVDTLYDLEEKINSAVFPGLQGGPHNHTIAGIAVALRQCLSEDFVQ 351
Query: 356 YQEQVLSNCAKFAQALSEKGYELVSGGTENHLVLVNLKNKGIDGSRVEKVLEAVHIAANK 415
Y EQVL N A+ + + GY L +GGT+NHL+LV+L+ G++G+R E VL+ HIA NK
Sbjct: 352 YGEQVLKNAKTLAERMKKHGYALATGGTDNHLLLVDLRPIGVEGARAEHVLDLAHIACNK 411
Query: 416 NTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFVKVAEYFDASVNLALKIKAESKGTKLKD 475
NT PGDVSA+ PGGIR+GTPALTSRGF E+DF KV ++ V +A K AE+ G LKD
Sbjct: 412 NTCPGDVSALRPGGIRLGTPALTSRGFQEQDFEKVGDFIHEGVQIAKKYNAEA-GKTLKD 470
Query: 476 FVETLQSSSYVQSEISKLRHDVEEFAKQFPTIGFE 510
F +++ + +++ L VEEF+ +F G E
Sbjct: 471 FKSFTETNEPFKKDVADLAKRVEEFSTKFEIPGNE 505
>GLYC_MOUSE (P50431) Serine hydroxymethyltransferase, cytosolic (EC
2.1.2.1) (Serine methylase) (Glycine
hydroxymethyltransferase) (SHMT)
Length = 478
Score = 567 bits (1461), Expect = e-161
Identities = 282/465 (60%), Positives = 353/465 (75%), Gaps = 4/465 (0%)
Query: 47 SWPKQLNSSLEEIDPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSIMTNKYSEG 106
S K L+ L++ D E+ II+ E RQ GLELI SENF S +V++A+GS + NKYSEG
Sbjct: 11 SHEKMLSQPLKDSDAEVYSIIKKESNRQRVGLELIASENFASRAVLEALGSSLNNKYSEG 70
Query: 107 YPGARYYGGNEYIDMAETLCQKRALEAFRLDPAKWGVNVQPLSGSPSNFHVYTALLKPHD 166
YPG RYYGG E+ID E LCQKRAL+A+ LDP WGVNVQP SGSP+NF VYTAL++PH
Sbjct: 71 YPGQRYYGGTEFIDELEMLCQKRALQAYHLDPQCWGVNVQPYSGSPANFAVYTALVEPHG 130
Query: 167 RIMALDLPHGGHLSHGYQTDTKKISAVSIFFETMPYRLDESTGYIDYDQLEKSATLFRPK 226
RIM LDLP GGHL+HG+ TD KKISA SIFFE+MPY++ TGYI+YDQLE++A+LF PK
Sbjct: 131 RIMGLDLPDGGHLTHGFMTDKKKISATSIFFESMPYKVYPETGYINYDQLEENASLFHPK 190
Query: 227 LIVAGASAYARLYDYARIRKVCDKQKAVMLADMAHISGLVAAGVIPSPFDYADVVTTTTH 286
LI+AG S Y+R DYAR+RK+ D A ++ADMAHISGLVAAGV+PSPF++ VVTTTTH
Sbjct: 191 LIIAGTSCYSRNLDYARLRKIADDNGAYLMADMAHISGLVAAGVVPSPFEHCHVVTTTTH 250
Query: 287 KSLRGPRGAMIFFRKGLKEVN-KQGKEVFYDYEDKINQAVFPGLQGGPHNHTITGLAVAL 345
K+LRG R MIF+RKG++ V+ K GKE +Y+ E IN AVFPGLQGGPHNH I G+AVAL
Sbjct: 251 KTLRGCRAGMIFYRKGVRSVDPKTGKETYYELESLINSAVFPGLQGGPHNHAIAGVAVAL 310
Query: 346 KQATTPEYKAYQEQVLSNCAKFAQALSEKGYELVSGGTENHLVLVNLKNKGIDGSRVEKV 405
KQA T E+K YQ QVL+NC + AL+E GY++V+GG++NHL+L++L++KG DG R EKV
Sbjct: 311 KQAMTTEFKIYQLQVLANCRALSDALTELGYKIVTGGSDNHLILMDLRSKGTDGGRAEKV 370
Query: 406 LEAVHIAANKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFVKVAEYFDASVNLALKIK 465
LEA IA NKNT PGD SA+ P G+R+GTPALTSRG +EEDF KVA + + L L+I+
Sbjct: 371 LEACSIACNKNTCPGDKSALRPSGLRLGTPALTSRGLLEEDFQKVAHFIHRGIELTLQIQ 430
Query: 466 AE--SKGTKLKDFVETLQSSSYVQSEISKLRHDVEEFAKQFPTIG 508
+ +K T LK+F E L +QS ++ LR +VE FA F G
Sbjct: 431 SHMATKAT-LKEFKEKLAGDEKIQSAVATLREEVENFASNFSLPG 474
>GLYM_RABIT (P14519) Serine hydroxymethyltransferase, mitochondrial
precursor (EC 2.1.2.1) (Serine methylase) (Glycine
hydroxymethyltransferase) (SHMT)
Length = 504
Score = 566 bits (1459), Expect = e-161
Identities = 280/456 (61%), Positives = 349/456 (76%), Gaps = 3/456 (0%)
Query: 55 SLEEIDPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSIMTNKYSEGYPGARYYG 114
SL + DPE+ ++++ EK RQ +GLELI SENF + ++A+GS + NKYSEGYPG RYYG
Sbjct: 48 SLSDTDPEMWELLQREKDRQCRGLELIASENFCIRAALEALGSCLNNKYSEGYPGKRYYG 107
Query: 115 GNEYIDMAETLCQKRALEAFRLDPAKWGVNVQPLSGSPSNFHVYTALLKPHDRIMALDLP 174
G E +D E LCQ+RALEAF LDPA+WGVNVQP SGSP+N YTALL+PHDRIM LDLP
Sbjct: 108 GAEVVDEIELLCQRRALEAFDLDPAQWGVNVQPYSGSPANLAAYTALLQPHDRIMGLDLP 167
Query: 175 HGGHLSHGYQTDTKKISAVSIFFETMPYRLDESTGYIDYDQLEKSATLFRPKLIVAGASA 234
GGHL+HGY +D K++SA SIFFE+MPY+L+ TG IDY+QL +A LFRP+LI+AG SA
Sbjct: 168 DGGHLTHGYMSDVKRVSATSIFFESMPYKLNPQTGLIDYEQLALTARLFRPRLIIAGTSA 227
Query: 235 YARLYDYARIRKVCDKQKAVMLADMAHISGLVAAGVIPSPFDYADVVTTTTHKSLRGPRG 294
YARL DYAR+R+VCD+ KA +LADMAHISGLVAA VIPSPF +ADVVTTTTHK+LRG R
Sbjct: 228 YARLIDYARMREVCDEVKAHLLADMAHISGLVAAKVIPSPFKHADVVTTTTHKTLRGARS 287
Query: 295 AMIFFRKGLKEVN-KQGKEVFYDYEDKINQAVFPGLQGGPHNHTITGLAVALKQATTPEY 353
+IF+RKG++ V+ K G+E+ Y +ED+IN AVFP LQGGPHNH I +AVALKQA TP +
Sbjct: 288 GLIFYRKGVRTVDPKTGQEIPYTFEDRINFAVFPSLQGGPHNHAIAAVAVALKQACTPMF 347
Query: 354 KAYQEQVLSNCAKFAQALSEKGYELVSGGTENHLVLVNLKNKGIDGSRVEKVLEAVHIAA 413
+ Y QVL N A AL E+GY LVSGGT+NHLVLV+L+ KG+DG+R E+VLE V I A
Sbjct: 348 REYSLQVLKNARAMADALLERGYSLVSGGTDNHLVLVDLRPKGLDGARAERVLELVSITA 407
Query: 414 NKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFVKVAEYFDASVNLALKIKAESKGTKL 473
NKNT PGD SA+ PGG+R+G PALTSR F E+DF +V ++ D VN+ L++K K KL
Sbjct: 408 NKNTCPGDRSAITPGGLRLGAPALTSRQFREDDFRRVVDFIDEGVNIGLEVK--RKTAKL 465
Query: 474 KDFVETLQSSSYVQSEISKLRHDVEEFAKQFPTIGF 509
+DF L ++ LR V++FA+ FP GF
Sbjct: 466 QDFKSFLLKDPETSQHLADLRRRVQQFARAFPMPGF 501
>GLYC_CANAL (O13426) Serine hydroxymethyltransferase, cytosolic (EC
2.1.2.1) (Serine methylase) (Glycine
hydroxymethyltransferase) (SHMT) (SHMII)
Length = 470
Score = 563 bits (1452), Expect = e-160
Identities = 275/453 (60%), Positives = 349/453 (76%), Gaps = 6/453 (1%)
Query: 56 LEEIDPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSIMTNKYSEGYPGARYYGG 115
L++ DPE+ II+ E RQ + LI SENFT+ +V A+G+ M NKYSEGYPGARYYGG
Sbjct: 18 LKDTDPEVDQIIKDEIDRQQHSIVLIASENFTTTAVFDALGTPMCNKYSEGYPGARYYGG 77
Query: 116 NEYIDMAETLCQKRALEAFRLDPAKWGVNVQPLSGSPSNFHVYTALLKPHDRIMALDLPH 175
NE+I E LCQ+RAL+AF L P KWGVNVQ LSGSP+N VY A++KPH+R+M LDLPH
Sbjct: 78 NEHIHRMELLCQERALKAFGLTPDKWGVNVQTLSGSPANLQVYQAIMKPHERLMGLDLPH 137
Query: 176 GGHLSHGYQTDTKKISAVSIFFETMPYRLDESTGYIDYDQLEKSATLFRPKLIVAGASAY 235
GGHLSHGYQTD++KISAVS +FETMPYR+D TG IDYD LEK+A L+RPK++VAG SAY
Sbjct: 138 GGHLSHGYQTDSRKISAVSTYFETMPYRVDLETGLIDYDMLEKTAVLYRPKVLVAGTSAY 197
Query: 236 ARLYDYARIRKVCDKQKAVMLADMAHISGLVAAGVIPSPFDYADVVTTTTHKSLRGPRGA 295
RL DY R+R++ DK A ++ DMAHISGL+AAGVIPSPF+YAD+VTTTTHKSLRGPRGA
Sbjct: 198 CRLIDYKRMREIADKVGAYLVVDMAHISGLIAAGVIPSPFEYADIVTTTTHKSLRGPRGA 257
Query: 296 MIFFRKGLKEVN-KQGKEVFYDYEDKINQAVFPGLQGGPHNHTITGLAVALKQATTPEYK 354
MIFFR+G++ VN K G+E+ YD E+ IN +VFPG QGGPHNHTI LA ALKQA TPE+K
Sbjct: 258 MIFFRRGVRSVNPKTGQEILYDLENPINFSVFPGHQGGPHNHTIAALATALKQANTPEFK 317
Query: 355 AYQEQVLSNCAKFAQALSEKGYELVSGGTENHLVLVNLKNKGIDGSRVEKVLEAVHIAAN 414
YQEQVL N ++KGY+LVS GT++H+VLV+LK+K IDG+RVE V E ++IA N
Sbjct: 318 EYQEQVLKNAKALESEFTKKGYKLVSDGTDSHMVLVSLKDKQIDGARVETVCEKINIALN 377
Query: 415 KNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFVKVAEYFDASVNLALKIKAE--SKGTK 472
KN++PGD SA+VPGG+R+G PA+T+RG EEDF K+ Y D +VN A +++++ K
Sbjct: 378 KNSIPGDKSALVPGGVRIGAPAMTTRGLGEEDFKKIVSYIDFAVNYAKEVQSQLPKDANK 437
Query: 473 LKDFVETLQSSSYVQSEISKLRHDVEEFAKQFP 505
LKDF + S ++ +R ++ ++A FP
Sbjct: 438 LKDFKNAVSGDS---EKLKAVRDEIYQWAGSFP 467
>GLYC_SHEEP (P35623) Serine hydroxymethyltransferase, cytosolic (EC
2.1.2.1) (Serine methylase) (Glycine
hydroxymethyltransferase) (SHMT)
Length = 483
Score = 560 bits (1442), Expect = e-159
Identities = 279/462 (60%), Positives = 351/462 (75%), Gaps = 4/462 (0%)
Query: 50 KQLNSSLEEIDPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSIMTNKYSEGYPG 109
K L L++ D E+ +II+ E RQ GLELI SENF S +V++A+GS + NKYSEGYPG
Sbjct: 19 KMLAQPLKDNDVEVYNIIKKESNRQRVGLELIASENFASRAVLEALGSCLNNKYSEGYPG 78
Query: 110 ARYYGGNEYIDMAETLCQKRALEAFRLDPAKWGVNVQPLSGSPSNFHVYTALLKPHDRIM 169
RYYGG E+ID E LCQKRAL+ + LDP WGVNVQP SGSP+NF VYTAL++PH RIM
Sbjct: 79 QRYYGGTEFIDELEVLCQKRALQVYGLDPECWGVNVQPYSGSPANFAVYTALVEPHGRIM 138
Query: 170 ALDLPHGGHLSHGYQTDTKKISAVSIFFETMPYRLDESTGYIDYDQLEKSATLFRPKLIV 229
LDLP GGHL+HG+ TD KKISA SIFFE+MPY+++ TGYI+YDQLE++A LF P+LI+
Sbjct: 139 GLDLPDGGHLTHGFMTDKKKISATSIFFESMPYKVNPDTGYINYDQLEENARLFHPRLII 198
Query: 230 AGASAYARLYDYARIRKVCDKQKAVMLADMAHISGLVAAGVIPSPFDYADVVTTTTHKSL 289
AG S Y+R DYAR+RK+ D A ++ADMAHISGLVAAGV+PSPF++ VV+TTTHK+L
Sbjct: 199 AGTSCYSRNLDYARLRKIADDNGAYLMADMAHISGLVAAGVVPSPFEHCHVVSTTTHKTL 258
Query: 290 RGPRGAMIFFRKGLKEVN-KQGKEVFYDYEDKINQAVFPGLQGGPHNHTITGLAVALKQA 348
RG R MIF+RKG++ V+ K GKE Y+ E IN AVFPGLQGGPHNH I G+AVALKQA
Sbjct: 259 RGCRAGMIFYRKGVRSVDPKTGKETRYNLESLINSAVFPGLQGGPHNHAIAGVAVALKQA 318
Query: 349 TTPEYKAYQEQVLSNCAKFAQALSEKGYELVSGGTENHLVLVNLKNKGIDGSRVEKVLEA 408
TPE++AYQ QV++NC A+AL GY +V+GG++NHL+LV+L++KG DG R EKVLEA
Sbjct: 319 MTPEFRAYQRQVVANCRALAEALMGLGYRVVTGGSDNHLILVDLRSKGTDGGRAEKVLEA 378
Query: 409 VHIAANKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFVKVAEYFDASVNLALKIKAES 468
IA NKNT PGD SA+ P G+R+GTPALTSRG +EEDF KVA + + L L+I+ ++
Sbjct: 379 CSIACNKNTCPGDKSALRPSGLRLGTPALTSRGLLEEDFRKVAHFIHRGIELTLQIQ-DA 437
Query: 469 KGTK--LKDFVETLQSSSYVQSEISKLRHDVEEFAKQFPTIG 508
G K LK+F+E L + Q ++ LR +VE FA FP G
Sbjct: 438 VGVKATLKEFMEKLAGAEEHQRAVTALRAEVESFATLFPLPG 479
>GLYC_RABIT (P07511) Serine hydroxymethyltransferase, cytosolic (EC
2.1.2.1) (Serine methylase) (Glycine
hydroxymethyltransferase) (SHMT)
Length = 483
Score = 558 bits (1439), Expect = e-159
Identities = 276/464 (59%), Positives = 348/464 (74%), Gaps = 2/464 (0%)
Query: 47 SWPKQLNSSLEEIDPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSIMTNKYSEG 106
S + L L++ D E+ DII+ E RQ GLELI SENF S +V++A+GS + NKYSEG
Sbjct: 16 SHEQMLAQPLKDSDAEVYDIIKKESNRQRVGLELIASENFASRAVLEALGSCLNNKYSEG 75
Query: 107 YPGARYYGGNEYIDMAETLCQKRALEAFRLDPAKWGVNVQPLSGSPSNFHVYTALLKPHD 166
YPG RYYGG E+ID ETLCQKRAL+A+ LDP WGVNVQP SGSP+NF VYTAL++PH
Sbjct: 76 YPGQRYYGGTEHIDELETLCQKRALQAYGLDPQCWGVNVQPYSGSPANFAVYTALVEPHG 135
Query: 167 RIMALDLPHGGHLSHGYQTDTKKISAVSIFFETMPYRLDESTGYIDYDQLEKSATLFRPK 226
RIM LDLP GGHL+HG+ TD KKISA SIFFE+M Y+++ TGYIDYD+LE++A LF PK
Sbjct: 136 RIMGLDLPDGGHLTHGFMTDKKKISATSIFFESMAYKVNPDTGYIDYDRLEENARLFHPK 195
Query: 227 LIVAGASAYARLYDYARIRKVCDKQKAVMLADMAHISGLVAAGVIPSPFDYADVVTTTTH 286
LI+AG S Y+R DY R+RK+ D+ A ++ADMAHISGLV AGV+PSPF++ VVTTTTH
Sbjct: 196 LIIAGTSCYSRNLDYGRLRKIADENGAYLMADMAHISGLVVAGVVPSPFEHCHVVTTTTH 255
Query: 287 KSLRGPRGAMIFFRKGLKEVN-KQGKEVFYDYEDKINQAVFPGLQGGPHNHTITGLAVAL 345
K+LRG R MIF+R+G++ V+ K GKE+ Y+ E IN AVFPGLQGGPHNH I G+AVAL
Sbjct: 256 KTLRGCRAGMIFYRRGVRSVDPKTGKEILYNLESLINSAVFPGLQGGPHNHAIAGVAVAL 315
Query: 346 KQATTPEYKAYQEQVLSNCAKFAQALSEKGYELVSGGTENHLVLVNLKNKGIDGSRVEKV 405
KQA TPE+K YQ QV++NC + AL E GY++V+GG++NHL+LV+L++KG DG R EKV
Sbjct: 316 KQAMTPEFKEYQRQVVANCRALSAALVELGYKIVTGGSDNHLILVDLRSKGTDGGRAEKV 375
Query: 406 LEAVHIAANKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFVKVAEYFDASVNLALKIK 465
LEA IA NKNT PGD SA+ P G+R+GTPALTSRG +E+DF KVA + + L ++I+
Sbjct: 376 LEACSIACNKNTCPGDKSALRPSGLRLGTPALTSRGLLEKDFQKVAHFIHRGIELTVQIQ 435
Query: 466 AES-KGTKLKDFVETLQSSSYVQSEISKLRHDVEEFAKQFPTIG 508
++ LK+F E L Q + LR +VE FA FP G
Sbjct: 436 DDTGPRATLKEFKEKLAGDEKHQRAVRALRQEVESFAALFPLPG 479
>GLYM_ASHGO (Q758F0) Serine hydroxymethyltransferase, mitochondrial
precursor (EC 2.1.2.1) (Serine methylase) (Glycine
hydroxymethyltransferase) (SHMT)
Length = 497
Score = 545 bits (1405), Expect = e-155
Identities = 262/460 (56%), Positives = 352/460 (75%), Gaps = 3/460 (0%)
Query: 52 LNSSLEEIDPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSIMTNKYSEGYPGAR 111
L+ ++E DPE+ DI+ E++RQ + + LIPSENFTS++VM +GS M NKYSEGYPG R
Sbjct: 36 LSQHVQEFDPEMYDILTKERSRQKRSITLIPSENFTSVAVMNLLGSEMQNKYSEGYPGQR 95
Query: 112 YYGGNEYIDMAETLCQKRALEAFRLDPAKWGVNVQPLSGSPSNFHVYTALLKPHDRIMAL 171
YYGGN+YIDMAE+LCQKRALE + LDPAKWGVNVQ LSG+P+N + Y+A+++ DR+M L
Sbjct: 96 YYGGNQYIDMAESLCQKRALELYGLDPAKWGVNVQSLSGAPANLYAYSAIMEVGDRMMGL 155
Query: 172 DLPHGGHLSHGYQTDT-KKISAVSIFFETMPYRLDESTGYIDYDQLEKSATLFRPKLIVA 230
DLPHGGHLSHGYQ KIS +S +F+TM YR+D +TG +DYD L +++ LFRPK+IVA
Sbjct: 156 DLPHGGHLSHGYQLQNGNKISYISKYFQTMAYRVDPATGLVDYDTLSETSKLFRPKVIVA 215
Query: 231 GASAYARLYDYARIRKVCDKQKAVMLADMAHISGLVAAGVIPSPFDYADVVTTTTHKSLR 290
G SAYAR+ DY R R++ D A +L+DMAH+SGLVAAGV PSPF+Y+D+VTTTTHKSLR
Sbjct: 216 GTSAYARVLDYKRFREIADACGAYLLSDMAHVSGLVAAGVHPSPFEYSDIVTTTTHKSLR 275
Query: 291 GPRGAMIFFRKGLKEVNKQGKEVFYDYEDKINQAVFPGLQGGPHNHTITGLAVALKQATT 350
GPRGAMIF+RKG+++V K+G E+ YD + +IN +VFP QGGPHNHTI+ LAVALKQA T
Sbjct: 276 GPRGAMIFYRKGIRKVTKKGTEIMYDLDKRINFSVFPAHQGGPHNHTISALAVALKQAAT 335
Query: 351 PEYKAYQEQVLSNCAKFAQALSEKGYELVSGGTENHLVLVNLKNKGIDGSRVEKVLEAVH 410
PE+K YQ V+ N F + LS++G+ LVSGGT+ HL+L++L GIDGSR+E +LE ++
Sbjct: 336 PEFKNYQTAVVENAKVFGEELSKRGFSLVSGGTDTHLLLIDLSPMGIDGSRLETILERLN 395
Query: 411 IAANKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFVKVAEYFDASVNLALKIKAES-- 468
IAANKNT+PGD SA+ P G+R+GTPA+T+RGF +F +VA Y + +V LA+ +K++
Sbjct: 396 IAANKNTIPGDKSALYPSGLRVGTPAMTTRGFGPAEFGRVAAYINEAVKLAIGLKSQEPV 455
Query: 469 KGTKLKDFVETLQSSSYVQSEISKLRHDVEEFAKQFPTIG 508
K + +S +++KL ++V ++ Q+P G
Sbjct: 456 DAKDAKTRLAHFKSFCAESEQVTKLANEVADWVAQYPVPG 495
>GLYC_ASHGO (Q75BQ6) Serine hydroxymethyltransferase, cytosolic (EC
2.1.2.1) (Serine methylase) (Glycine
hydroxymethyltransferase) (SHMT)
Length = 469
Score = 545 bits (1404), Expect = e-154
Identities = 268/462 (58%), Positives = 346/462 (74%), Gaps = 6/462 (1%)
Query: 47 SWPKQLNSSLEEIDPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSIMTNKYSEG 106
S K ++S L E DPE+ II+ E RQ + LI SEN TS +V A+G+ M NKYSEG
Sbjct: 8 SHKKLISSHLSESDPEVDAIIKDEIDRQKHSIVLIASENLTSTAVFDALGTPMCNKYSEG 67
Query: 107 YPGARYYGGNEYIDMAETLCQKRALEAFRLDPAKWGVNVQPLSGSPSNFHVYTALLKPHD 166
YPGARYYGGN++ID E LCQ+RALEAF + P +WGVNVQ LSGSP+N VY AL+KPH+
Sbjct: 68 YPGARYYGGNQHIDRMELLCQRRALEAFHVTPDRWGVNVQSLSGSPANLQVYQALMKPHE 127
Query: 167 RIMALDLPHGGHLSHGYQTDTKKISAVSIFFETMPYRLDESTGYIDYDQLEKSATLFRPK 226
R+M L LP GGHLSHGYQT+T+KISAVS +FE+ PYR+D TG IDYD LEK+A L+RPK
Sbjct: 128 RLMGLHLPDGGHLSHGYQTETRKISAVSTYFESFPYRVDPETGIIDYDTLEKNAVLYRPK 187
Query: 227 LIVAGASAYARLYDYARIRKVCDKQKAVMLADMAHISGLVAAGVIPSPFDYADVVTTTTH 286
++VAG SAY RL DY R+R++ DK A ++ DMAHISGLVAAGVIPSPF+YAD+VTTTTH
Sbjct: 188 ILVAGTSAYCRLIDYKRMREIADKVGAYLMVDMAHISGLVAAGVIPSPFEYADIVTTTTH 247
Query: 287 KSLRGPRGAMIFFRKGLKEVN-KQGKEVFYDYEDKINQAVFPGLQGGPHNHTITGLAVAL 345
KSLRGPRGAMIFFR+G++ V+ K G+EV YD E IN +VFPG QGGPHNHTI+ LA AL
Sbjct: 248 KSLRGPRGAMIFFRRGVRSVHPKTGEEVMYDLEGPINFSVFPGHQGGPHNHTISALATAL 307
Query: 346 KQATTPEYKAYQEQVLSNCAKFAQALSEKGYELVSGGTENHLVLVNLKNKGIDGSRVEKV 405
KQATTPE++ YQE VL N + Y LVS GT++H+VLV+L+ KG+DG+RVE V
Sbjct: 308 KQATTPEFREYQELVLKNAKVLETEFKKLNYRLVSDGTDSHMVLVSLREKGVDGARVEHV 367
Query: 406 LEAVHIAANKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFVKVAEYFDASVNLALKIK 465
E ++IA NKN++PGD SA+VPGG+R+G PA+T+RG EEDF ++ Y + +V +A I+
Sbjct: 368 CEKINIALNKNSIPGDKSALVPGGVRIGAPAMTTRGMGEEDFARIVGYINRAVEIARSIQ 427
Query: 466 AE--SKGTKLKDFVETLQSSSYVQSEISKLRHDVEEFAKQFP 505
+ +LKDF ++ + EI++L ++ + +++P
Sbjct: 428 QSLPKEANRLKDFKAKVEGGT---DEIAQLAQEIYSWTEEYP 466
>GLYC_CANGA (Q6FUP6) Serine hydroxymethyltransferase, cytosolic (EC
2.1.2.1) (Serine methylase) (Glycine
hydroxymethyltransferase) (SHMT)
Length = 469
Score = 544 bits (1401), Expect = e-154
Identities = 265/459 (57%), Positives = 342/459 (73%), Gaps = 6/459 (1%)
Query: 50 KQLNSSLEEIDPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSIMTNKYSEGYPG 109
K ++ L E DPE+ II+ E RQ ++LI SENFT+ SV A+G+ + NKYSEGYPG
Sbjct: 11 KMVSGHLSETDPEVEQIIKDEVDRQKHSIDLIASENFTTTSVFDALGTPLCNKYSEGYPG 70
Query: 110 ARYYGGNEYIDMAETLCQKRALEAFRLDPAKWGVNVQPLSGSPSNFHVYTALLKPHDRIM 169
ARYYGGNE+ID E LCQ+RALEAF + P +WGVNVQ LSGSP+N VY AL+KPH+R+M
Sbjct: 71 ARYYGGNEHIDRIERLCQQRALEAFHVTPDRWGVNVQTLSGSPANLQVYQALMKPHERLM 130
Query: 170 ALDLPHGGHLSHGYQTDTKKISAVSIFFETMPYRLDESTGYIDYDQLEKSATLFRPKLIV 229
L LP GGHLSHGY T+ +KISAVS +FE+ PYR++ TG IDYD LEK+A L+RPK++V
Sbjct: 131 GLYLPDGGHLSHGYATENRKISAVSTYFESFPYRVNPETGIIDYDTLEKNAILYRPKILV 190
Query: 230 AGASAYARLYDYARIRKVCDKQKAVMLADMAHISGLVAAGVIPSPFDYADVVTTTTHKSL 289
AG SAY RL DY R+R++ DK A ++ DMAHISGLVAAGVIPSPF+YAD+VTTTTHKSL
Sbjct: 191 AGTSAYCRLIDYKRMREIADKCGAYLMVDMAHISGLVAAGVIPSPFEYADIVTTTTHKSL 250
Query: 290 RGPRGAMIFFRKGLKEVN-KQGKEVFYDYEDKINQAVFPGLQGGPHNHTITGLAVALKQA 348
RGPRGAMIFFR+G++ VN K GKE+ YD E+ IN +VFPG QGGPHNHTI LA ALKQA
Sbjct: 251 RGPRGAMIFFRRGIRSVNQKTGKEIPYDLENPINFSVFPGHQGGPHNHTIAALATALKQA 310
Query: 349 TTPEYKAYQEQVLSNCAKFAQALSEKGYELVSGGTENHLVLVNLKNKGIDGSRVEKVLEA 408
TPE+K YQ QVL N GY LVS GT++H+VLV+L+ KG+DG+RVE V E
Sbjct: 311 ATPEFKEYQTQVLKNAKALENEFQTLGYRLVSNGTDSHMVLVSLREKGVDGARVEYVCEK 370
Query: 409 VHIAANKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFVKVAEYFDASVNLALKIKAE- 467
++IA NKN++PGD SA+VPGG+R+G PA+T+RG EEDF ++ Y D +V A + ++
Sbjct: 371 INIALNKNSIPGDKSALVPGGVRIGAPAMTTRGMGEEDFHRIVRYIDQAVKFAEQTQSSL 430
Query: 468 -SKGTKLKDFVETLQSSSYVQSEISKLRHDVEEFAKQFP 505
+ KLKDF + + +++ L+ ++ ++ ++P
Sbjct: 431 PKEANKLKDFKAKVDE---IADQLAPLKKEIYDWTAEYP 466
Database: sprot
Posted date: Nov 25, 2004 10:54 AM
Number of letters in database: 59,974,054
Number of sequences in database: 164,201
Lambda K H
0.315 0.132 0.373
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 59,622,108
Number of Sequences: 164201
Number of extensions: 2547968
Number of successful extensions: 8238
Number of sequences better than 10.0: 202
Number of HSP's better than 10.0 without gapping: 178
Number of HSP's successfully gapped in prelim test: 24
Number of HSP's that attempted gapping in prelim test: 7378
Number of HSP's gapped (non-prelim): 208
length of query: 518
length of database: 59,974,054
effective HSP length: 115
effective length of query: 403
effective length of database: 41,090,939
effective search space: 16559648417
effective search space used: 16559648417
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 68 (30.8 bits)
Medicago: description of AC126010.6