BLAST2 result
BLASTP 2.2.2 [Dec-14-2001]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= AC126006.5 + phase: 0
(652 letters)
Database: sprot
164,201 sequences; 59,974,054 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
CC7_SCHPO (P41892) Cell division control protein 7 (EC 2.7.1.-) 83 2e-15
WIS4_SCHPO (O14299) MAP kinase kinase kinase wis4 (EC 2.7.1.-) (... 82 4e-15
K6A2_MOUSE (Q9WUT3) Ribosomal protein S6 kinase alpha 2 (EC 2.7.... 82 6e-15
K6AA_CHICK (P18652) Ribosomal protein S6 kinase II alpha (EC 2.7... 81 1e-14
K6A1_HUMAN (Q15418) Ribosomal protein S6 kinase alpha 1 (EC 2.7.... 81 1e-14
K6AA_XENLA (P10665) Ribosomal protein S6 kinase II alpha (EC 2.7... 80 2e-14
K6A2_HUMAN (Q15349) Ribosomal protein S6 kinase alpha 2 (EC 2.7.... 79 4e-14
KRAC_DICDI (P54644) RAC-family serine/threonine-protein kinase h... 79 5e-14
ACK1_MOUSE (O54967) Activated CDC42 kinase 1 (EC 2.7.1.112) (ACK... 77 1e-13
MATK_MOUSE (P41242) Megakaryocyte-associated tyrosine-protein ki... 77 1e-13
ACK1_HUMAN (Q07912) Activated CDC42 kinase 1 (EC 2.7.1.112) (ACK-1) 77 1e-13
K6A6_HUMAN (Q9UK32) Ribosomal protein S6 kinase alpha 6 (EC 2.7.... 77 2e-13
ACK2_BOVIN (O02742) Activated CDC42 kinase 2 (EC 2.7.1.112) (ACK-2) 76 2e-13
PK2_DICDI (P28178) Protein kinase 2 (EC 2.7.1.-) 76 3e-13
MATK_RAT (P41243) Megakaryocyte-associated tyrosine-protein kina... 76 3e-13
KPC4_DROME (P83099) Putative protein kinase C, delta type homolo... 76 3e-13
PLK3_CAEEL (Q20845) Serine/threonine-protein kinase plk-3 (EC 2.... 75 4e-13
PKAA_STRCO (P54739) Serine/threonine protein kinase pkaA (EC 2.7... 75 4e-13
PKAB_STRCO (P54740) Serine/threonine protein kinase pkaB (EC 2.7... 74 2e-12
BCK1_YEAST (Q01389) Serine/threonine-protein kinase BCK1/SLK1/SS... 74 2e-12
>CC7_SCHPO (P41892) Cell division control protein 7 (EC 2.7.1.-)
Length = 1062
Score = 83.2 bits (204), Expect = 2e-15
Identities = 61/247 (24%), Positives = 115/247 (45%), Gaps = 34/247 (13%)
Query: 173 VAVKKVVLNEGMDLDWMLGKLEDLRRTSMWCRNVCTFHGAMKVDEGLCLVMDKCFGSVQS 232
VAVKKV L++ + D + K+E ++ N+ + G+ + ++ LC++++ C
Sbjct: 35 VAVKKVKLSKMLKSDLSVIKMEIDLLKNLDHPNIVKYRGSYQTNDSLCIILEYCENGSLR 94
Query: 233 EMLRNEGRLTLEQVLRYGADIARGVVELHAAGVVCMSLKPSNLLLDANGHAVVSDYGLAT 292
+ +N G++ V Y + +G++ LH GV+ +K +N+L +G ++D+G+AT
Sbjct: 95 SICKNFGKIPENLVALYTFQVLQGLLYLHNQGVIHRDIKGANILTTKDGTIKLADFGVAT 154
Query: 293 ILKKPSCWKARPECDSAKIHSCMECIMLSPHYTAPEAWEPVKKSLNLFWDDGIGISPESD 352
+ ++ + HS ++ SP++ APE E V G + SD
Sbjct: 155 ------------KINALEDHS----VVGSPYWMAPEVIELV------------GATTASD 186
Query: 353 AWSFGCTLVEMCTGAIPWAGLSAEEIYRQVVKAKKQPPQYASVVGGGIPRELWKMIGECL 412
WS GCT++E+ G P+ L ++VK + P + I + +C
Sbjct: 187 IWSVGCTVIELLDGNPPYYDLDPTSALFRMVKDEHPP------LPSNISSAAKSFLMQCF 240
Query: 413 QFKPSKR 419
Q P+ R
Sbjct: 241 QKDPNLR 247
>WIS4_SCHPO (O14299) MAP kinase kinase kinase wis4 (EC 2.7.1.-) (MAP
kinase kinase kinase wak1) (MAP kinase kinase kinase
wik1)
Length = 1401
Score = 82.0 bits (201), Expect = 4e-15
Identities = 63/219 (28%), Positives = 101/219 (45%), Gaps = 23/219 (10%)
Query: 205 NVCTFHGAMKVDEGLCLVMDKCFGSVQSEMLRNEGRLTLEQVLR-YGADIARGVVELHAA 263
NV T++G E + + M+ C G +++L + GR+ E VL+ Y + G+ +H+
Sbjct: 1097 NVVTYYGVEVHREKVYIFMEFCQGGSLADLLAH-GRIEDENVLKVYVVQLLEGLAYIHSQ 1155
Query: 264 GVVCMSLKPSNLLLDANGHAVVSDYGLATILKKPSCWKARPECDSAKIHSCMECIMLSPH 323
++ +KP+N+LLD G SD+G A + P+ PE I ++ + +P
Sbjct: 1156 HILHRDIKPANILLDHRGMIKYSDFGSALYVSPPT----DPEVRYEDIQPELQHLAGTPM 1211
Query: 324 YTAPEAWEPVKKSLNLFWDDGIGISPESDAWSFGCTLVEMCTGAIPWAGLSAEEIYRQVV 383
Y APE KK G D WS GC ++EM TG+ PW+ + E V
Sbjct: 1212 YMAPEIILGTKK----------GDFGAMDIWSLGCVILEMMTGSTPWSEMDNEWAIMYHV 1261
Query: 384 KAKKQP--PQYASVVGGGIPRELWKMIGECLQFKPSKRP 420
A P PQ + + R+ I +C + P +RP
Sbjct: 1262 AAMHTPSIPQNEKI--SSLARD---FIEQCFERDPEQRP 1295
>K6A2_MOUSE (Q9WUT3) Ribosomal protein S6 kinase alpha 2 (EC
2.7.1.37) (S6K-alpha 2) (90 kDa ribosomal protein S6
kinase 2) (p90-RSK 2) (Ribosomal S6 kinase 3) (RSK-3)
(pp90RSK3) (Protein-tyrosine kinase Mpk-9) (MAP
kinase-activated protein kinase 1c) (MA
Length = 733
Score = 81.6 bits (200), Expect = 6e-15
Identities = 81/306 (26%), Positives = 125/306 (40%), Gaps = 45/306 (14%)
Query: 117 RKNSRGSQASSSG----GCAPVIEVGVH----------QDLKLVRRIGEGRRAGVEMWSA 162
RK SR +S S G I++ H +L++ +G+G V +
Sbjct: 19 RKKSRSKSSSLSRLEEEGIVKEIDISNHVKEGFEKADPSQFELLKVLGQGSYGKVFLVRK 78
Query: 163 VIGG--GRCKHQVAVKKVVLNEGMDLDWMLGKLEDLRRTSMWCRNVCTFHGAMKVDEGLC 220
V G G+ +KK L D + K+E + + H A + + L
Sbjct: 79 VTGSDAGQLYAMKVLKKATLKVR---DRVRSKMERDILAEVNHPFIVKLHYAFQTEGKLY 135
Query: 221 LVMDKCFGSVQSEMLRNEGRLTLEQVLRYGADIARGVVELHAAGVVCMSLKPSNLLLDAN 280
L++D G L E T E V Y A++A + LH G++ LKP N+LLD
Sbjct: 136 LILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALALDHLHGLGIIYRDLKPENILLDEE 195
Query: 281 GHAVVSDYGLATILKKPSCWKARPECDSAKIHSCMECIMLSPHYTAPEAWEPVKKSLNLF 340
GH ++D+GL+ K + D C + Y APE V +
Sbjct: 196 GHIKITDFGLS---------KEATDHDKRAYSFCG-----TIEYMAPEV---VNRR---- 234
Query: 341 WDDGIGISPESDAWSFGCTLVEMCTGAIPWAGLSAEEIYRQVVKAKKQPPQYASVVGGGI 400
G + +D WSFG + EM TG++P+ G +E ++KAK PQ+ S +
Sbjct: 235 -----GHTQSADWWSFGVLMFEMLTGSLPFQGKDRKETMALILKAKLGMPQFLSAEAQSL 289
Query: 401 PRELWK 406
R L+K
Sbjct: 290 LRALFK 295
Score = 38.5 bits (88), Expect = 0.056
Identities = 55/213 (25%), Positives = 91/213 (41%), Gaps = 43/213 (20%)
Query: 253 IARGVVELHAAGVVCMSLKPSNLL-LDANGHAV---VSDYGLATILKKPSCWKARPECDS 308
IAR + LH+ GVV LKPSN+L +D +G+ + D+G A L+ +
Sbjct: 516 IARTMDYLHSQGVVHRDLKPSNILYMDESGNPESIRICDFGFAKQLRAEN---------- 565
Query: 309 AKIHSCMECIMLSPHYTAP-EAWEPVKKSLNLFWDDGIGISPESDAWSFGCTLVEMCTGA 367
++++P YTA A E +K+ G D WS G L M G
Sbjct: 566 --------GLLMTPCYTANFVAPEVLKRQ---------GYDAACDVWSLGILLYTMLAGF 608
Query: 368 IPWAG---LSAEEIYRQVVKAKKQPPQYASVVGG--GIPRELWKMIGECLQFKPSKRPTF 422
P+A + EEI ++ K YA G I ++ + L P +R T
Sbjct: 609 TPFANGPDDTPEEILARIGSGK-----YALSGGNWDSISDAAKDVVSKMLHVDPQQRLTA 663
Query: 423 NAMLA-IFLRHLQEIPRSPPASPDNDLVKGSVS 454
+L ++ + + + ++ + D LVKG+++
Sbjct: 664 VQVLKHPWIVNREYLSQNQLSRQDVHLVKGAMA 696
>K6AA_CHICK (P18652) Ribosomal protein S6 kinase II alpha (EC
2.7.1.37) (S6KII-alpha) (P90-RSK) (MAP kinase-activated
protein kinase 1) (MAPK-activated protein kinase 1)
(MAPKAP kinase 1) (MAPKAPK-1)
Length = 752
Score = 80.9 bits (198), Expect = 1e-14
Identities = 60/201 (29%), Positives = 91/201 (44%), Gaps = 26/201 (12%)
Query: 206 VCTFHGAMKVDEGLCLVMDKCFGSVQSEMLRNEGRLTLEQVLRYGADIARGVVELHAAGV 265
V H A + + L L++D G L E T E V Y A++A G+ LH+ G+
Sbjct: 142 VVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALGLDHLHSLGI 201
Query: 266 VCMSLKPSNLLLDANGHAVVSDYGLATILKKPSCWKARPECDSAKIHSCMECIMLSPHYT 325
+ LKP N+LLD GH ++D+GL+ K + + C + Y
Sbjct: 202 IYRDLKPENILLDEEGHIKLTDFGLS---------KEAIDHEKKAYSFCG-----TVEYM 247
Query: 326 APEAWEPVKKSLNLFWDDGIGISPESDAWSFGCTLVEMCTGAIPWAGLSAEEIYRQVVKA 385
APE V + G S +D WS+G + EM TG++P+ G +E ++KA
Sbjct: 248 APEV---VNRQ---------GHSHSADWWSYGVLMFEMLTGSLPFQGKDRKETMTLILKA 295
Query: 386 KKQPPQYASVVGGGIPRELWK 406
K PQ+ S + R L+K
Sbjct: 296 KLGMPQFLSAEAQSLLRALFK 316
Score = 45.4 bits (106), Expect = 5e-04
Identities = 61/229 (26%), Positives = 96/229 (41%), Gaps = 47/229 (20%)
Query: 253 IARGVVELHAAGVVCMSLKPSNLL-LDANGHAV---VSDYGLATILKKPSCWKARPECDS 308
I + V LH+ GVV LKPSN+L +D +G+ + D+G A L+ +
Sbjct: 536 ICKTVEYLHSQGVVHRDLKPSNILYVDESGNPESIRICDFGFAKQLRAEN---------- 585
Query: 309 AKIHSCMECIMLSPHYTAPEAWEPVKKSLNLFWDDGIGISPESDAWSFGCTLVEMCTGAI 368
++++P YTA V K +D+G D WS G L M G
Sbjct: 586 --------GLLMTPCYTANFVAPEVLKRQG--YDEG------CDIWSLGVLLYTMLAGCT 629
Query: 369 PWA---GLSAEEIYRQVVKAKKQPPQYASVVGGG---IPRELWKMIGECLQFKPSKRPTF 422
P+A + EEI ++ K SV GG I ++ + L P +R T
Sbjct: 630 PFANGPSDTPEEILTRIGGGK------FSVNGGNWDTISDVAKDLVSKMLHVDPHQRLTA 683
Query: 423 NAMLA-IFLRHLQEIPRSPPASPDNDLVKGSV----SNVTEASPVPELE 466
+L ++ +P+S D LVKG++ S + + P P+L+
Sbjct: 684 KQVLQHPWITQKDSLPQSQLNYQDVQLVKGAMAATYSALNSSKPSPQLK 732
>K6A1_HUMAN (Q15418) Ribosomal protein S6 kinase alpha 1 (EC
2.7.1.37) (S6K-alpha 1) (90 kDa ribosomal protein S6
kinase 1) (p90-RSK 1) (Ribosomal S6 kinase 1) (RSK-1)
(pp90RSK1)
Length = 735
Score = 80.9 bits (198), Expect = 1e-14
Identities = 60/201 (29%), Positives = 91/201 (44%), Gaps = 26/201 (12%)
Query: 206 VCTFHGAMKVDEGLCLVMDKCFGSVQSEMLRNEGRLTLEQVLRYGADIARGVVELHAAGV 265
V H A + + L L++D G L E T E V Y A++A G+ LH+ G+
Sbjct: 124 VVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALGLDHLHSLGI 183
Query: 266 VCMSLKPSNLLLDANGHAVVSDYGLATILKKPSCWKARPECDSAKIHSCMECIMLSPHYT 325
+ LKP N+LLD GH ++D+GL+ K + + C + Y
Sbjct: 184 IYRDLKPENILLDEEGHIKLTDFGLS---------KEAIDHEKKAYSFCG-----TVEYM 229
Query: 326 APEAWEPVKKSLNLFWDDGIGISPESDAWSFGCTLVEMCTGAIPWAGLSAEEIYRQVVKA 385
APE V + G S +D WS+G + EM TG++P+ G +E ++KA
Sbjct: 230 APEV---VNRQ---------GHSHSADWWSYGVLMFEMLTGSLPFQGKDRKETMTLILKA 277
Query: 386 KKQPPQYASVVGGGIPRELWK 406
K PQ+ S + R L+K
Sbjct: 278 KLGMPQFLSTEAQSLLRALFK 298
Score = 46.6 bits (109), Expect = 2e-04
Identities = 60/228 (26%), Positives = 97/228 (42%), Gaps = 45/228 (19%)
Query: 253 IARGVVELHAAGVVCMSLKPSNLL-LDANGHAVVSDYGLATILKKPSCWKARPECD--SA 309
I + V LH+ GVV LKPSN+L +D +G+ P C + CD A
Sbjct: 519 IGKTVEYLHSQGVVHRDLKPSNILYVDESGN--------------PECLRI---CDFGFA 561
Query: 310 KIHSCMECIMLSPHYTAPEAWEPVKKSLNLFWDDGIGISPESDAWSFGCTLVEMCTGAIP 369
K ++++P YTA V K +D+G D WS G L M G P
Sbjct: 562 KQLRAENGLLMTPCYTANFVAPEVLKRQG--YDEG------CDIWSLGILLYTMLAGYTP 613
Query: 370 WA---GLSAEEIYRQVVKAKKQPPQYASVVGGG---IPRELWKMIGECLQFKPSKRPTFN 423
+A + EEI ++ K ++ GG + ++ + L P +R T
Sbjct: 614 FANGPSDTPEEILTRIGSGK------FTLSGGNWNTVSETAKDLVSKMLHVDPHQRLTAK 667
Query: 424 AMLA-IFLRHLQEIPRSPPASPDNDLVKGSV----SNVTEASPVPELE 466
+L ++ ++P+S + D LVKG++ S + + P P+L+
Sbjct: 668 QVLQHPWVTQKDKLPQSQLSHQDLQLVKGAMAATYSALNSSKPTPQLK 715
>K6AA_XENLA (P10665) Ribosomal protein S6 kinase II alpha (EC
2.7.1.37) (S6KII-alpha) (P90-RSK) (MAP kinase-activated
protein kinase 1) (MAPK-activated protein kinase 1)
(MAPKAP kinase 1) (MAPKAPK-1)
Length = 733
Score = 79.7 bits (195), Expect = 2e-14
Identities = 60/201 (29%), Positives = 91/201 (44%), Gaps = 26/201 (12%)
Query: 206 VCTFHGAMKVDEGLCLVMDKCFGSVQSEMLRNEGRLTLEQVLRYGADIARGVVELHAAGV 265
V H A + + L L++D G L E T E V Y A++A G+ LH+ G+
Sbjct: 124 VVRLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALGLDHLHSLGI 183
Query: 266 VCMSLKPSNLLLDANGHAVVSDYGLATILKKPSCWKARPECDSAKIHSCMECIMLSPHYT 325
+ LKP N+LLD GH ++D+GL+ K + + C + Y
Sbjct: 184 IYRDLKPENILLDEEGHIKLTDFGLS---------KEAIDHEKKAYSFCG-----TVEYM 229
Query: 326 APEAWEPVKKSLNLFWDDGIGISPESDAWSFGCTLVEMCTGAIPWAGLSAEEIYRQVVKA 385
APE V + G S +D WS+G + EM TG++P+ G +E ++KA
Sbjct: 230 APEV---VNRQ---------GHSHSADWWSYGVLMFEMLTGSLPFQGKDRKETMTLILKA 277
Query: 386 KKQPPQYASVVGGGIPRELWK 406
K PQ+ S + R L+K
Sbjct: 278 KLGMPQFLSNEAQSLLRALFK 298
Score = 45.1 bits (105), Expect = 6e-04
Identities = 59/229 (25%), Positives = 94/229 (40%), Gaps = 47/229 (20%)
Query: 253 IARGVVELHAAGVVCMSLKPSNLL-LDANGHAV---VSDYGLATILKKPSCWKARPECDS 308
+ + V LH+ GVV LKPSN+L +D +G + D+G A L+ +
Sbjct: 517 VCKTVENLHSQGVVHRDLKPSNILYVDESGDPESIRICDFGFAKQLRADN---------- 566
Query: 309 AKIHSCMECIMLSPHYTAPEAWEPVKKSLNLFWDDGIGISPESDAWSFGCTLVEMCTGAI 368
++++P YTA V K +D+G D WS G L M G
Sbjct: 567 --------GLLMTPCYTANFVAPEVLKRQG--YDEG------CDIWSLGILLYTMLAGYT 610
Query: 369 PWA---GLSAEEIYRQVVKAKKQPPQYASVVGGG---IPRELWKMIGECLQFKPSKRPTF 422
P+A G + EEI ++ K ++ GG + ++ L P KR T
Sbjct: 611 PFANGLGDTPEEILARIGSGK------FTLRGGNWNTVSAAAKDLVSRMLHVDPHKRLTA 664
Query: 423 NAMLA-IFLRHLQEIPRSPPASPDNDLVKGSV----SNVTEASPVPELE 466
+L ++ +P+S D LVKG++ S + + P P L+
Sbjct: 665 KQVLQHEWITKRDALPQSQLNRQDVHLVKGAMAATYSALNSSKPTPLLQ 713
>K6A2_HUMAN (Q15349) Ribosomal protein S6 kinase alpha 2 (EC
2.7.1.37) (S6K-alpha 2) (90 kDa ribosomal protein S6
kinase 2) (p90-RSK 2) (Ribosomal S6 kinase 3) (RSK-3)
(pp90RSK3)
Length = 733
Score = 79.0 bits (193), Expect = 4e-14
Identities = 59/201 (29%), Positives = 90/201 (44%), Gaps = 26/201 (12%)
Query: 206 VCTFHGAMKVDEGLCLVMDKCFGSVQSEMLRNEGRLTLEQVLRYGADIARGVVELHAAGV 265
+ H A + + L L++D G L E T E V Y A++A + LH+ G+
Sbjct: 121 IVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALALDHLHSLGI 180
Query: 266 VCMSLKPSNLLLDANGHAVVSDYGLATILKKPSCWKARPECDSAKIHSCMECIMLSPHYT 325
+ LKP N+LLD GH ++D+GL+ K + D C + Y
Sbjct: 181 IYRDLKPENILLDEEGHIKITDFGLS---------KEAIDHDKRAYSFCG-----TIEYM 226
Query: 326 APEAWEPVKKSLNLFWDDGIGISPESDAWSFGCTLVEMCTGAIPWAGLSAEEIYRQVVKA 385
APE V + G + +D WSFG + EM TG++P+ G +E ++KA
Sbjct: 227 APEV---VNRR---------GHTQSADWWSFGVLMFEMLTGSLPFQGKDRKETMALILKA 274
Query: 386 KKQPPQYASVVGGGIPRELWK 406
K PQ+ S + R L+K
Sbjct: 275 KLGMPQFLSGEAQSLLRALFK 295
Score = 33.1 bits (74), Expect = 2.3
Identities = 35/117 (29%), Positives = 48/117 (40%), Gaps = 32/117 (27%)
Query: 260 LHAAGVVCMSLKPSNLLL-DANGHAV---VSDYGLATILKKPSCWKARPECDSAKIHSCM 315
LH+ GVV LKPSN+L D +G V D+G A L+ +
Sbjct: 523 LHSQGVVHRDLKPSNILYRDESGSPESIRVCDFGFAKQLRAGN----------------- 565
Query: 316 ECIMLSPHYTAP-EAWEPVKKSLNLFWDDGIGISPESDAWSFGCTLVEMCTGAIPWA 371
++++P YTA A E +K+ G D WS G L M G P+A
Sbjct: 566 -GLLMTPCYTANFVAPEVLKRQ---------GYDAACDIWSLGILLYTMLAGFTPFA 612
>KRAC_DICDI (P54644) RAC-family serine/threonine-protein kinase
homolog (EC 2.7.1.37)
Length = 444
Score = 78.6 bits (192), Expect = 5e-14
Identities = 71/259 (27%), Positives = 110/259 (42%), Gaps = 33/259 (12%)
Query: 212 AMKVDEGLCLVMDKCFGSVQSEMLRNEGRLTLEQVLRYGADIARGVVELHAAGVVCMSLK 271
+ + ++ L ++D G L+ + + T ++V YGA+I + LH +GV+ LK
Sbjct: 186 SFQTEDKLYFILDYVNGGELFYHLQKDKKFTEDRVRYYGAEIVLALEHLHLSGVIYRDLK 245
Query: 272 PSNLLLDANGHAVVSDYGLATILKKPSCWKARPECDSAKIHSCMECIMLSPHYTAPEAWE 331
P NLLL GH ++D+GL K C +P Y APE +
Sbjct: 246 PENLLLTNEGHICMTDFGLCKEGLLTPTDKTGTFCG-------------TPEYLAPEVLQ 292
Query: 332 PVKKSLNLFWDDGIGISPESDAWSFGCTLVEMCTGAIPWAGLSAEEIYRQVVKAKKQPPQ 391
G G + D WSFG L EM TG P+ +E+YR+++ K P
Sbjct: 293 ------------GNGYGKQVDWWSFGSLLYEMLTGLPPFYNQDVQEMYRKIMMEKLSFPH 340
Query: 392 YASVVGGGIPRELWKMIGECLQFKPS--KRPTFNAMLAIFLRHLQEIPRSPPASPDNDLV 449
+ S + +L + E P+ KR F + + IP PP P+ V
Sbjct: 341 FISPDARSLLEQLLERDPEKRLADPNLIKRHPFFRSIDWEQLFQKNIP--PPFIPN---V 395
Query: 450 KGSVSNVTEASPVPELEIP 468
KGS ++ ++ PV E P
Sbjct: 396 KGS-ADTSQIDPVFTDEAP 413
>ACK1_MOUSE (O54967) Activated CDC42 kinase 1 (EC 2.7.1.112) (ACK-1)
(Non-receptor protein tyrosine kinase Ack) (Tyrosine
kinase non-receptor protein 2)
Length = 1055
Score = 77.4 bits (189), Expect = 1e-13
Identities = 71/289 (24%), Positives = 122/289 (41%), Gaps = 35/289 (12%)
Query: 141 QDLKLVRRIGEGRRAGVEM--WSAVIGGGRCKHQVAVKKVVLNEGMDLDWMLGKLEDLRR 198
+DL+L+ ++G+G V W A G +K VL++ +D + ++ +
Sbjct: 124 KDLRLLEKLGDGSFGVVRRGEWDAPAGKTVSVAVKCLKPDVLSQPEAMDDFIREVNAMH- 182
Query: 199 TSMWCRNVCTFHGAMKVDEGLCLVMDKCFGSVQSEMLRNEGRLTLEQVLRYGADIARGVV 258
S+ RN+ +G + + GS+ + +++G L + RY +A G+
Sbjct: 183 -SLDHRNLIRLYGVVLTLPMKMVTELAPLGSLLDRLRKHQGHFLLGTLSRYAVQVAEGMA 241
Query: 259 ELHAAGVVCMSLKPSNLLLDANGHAVVSDYGLATILKKPSCWKARPECDSAKIHSCMECI 318
L + + L NLLL + D+GL +A P+ D +
Sbjct: 242 YLESKRFIHRDLAARNLLLATRDLVKIGDFGL---------MRALPQND--------DHY 284
Query: 319 MLSPHYTAPEAW-EPVKKSLNLFWDDGIGISPESDAWSFGCTLVEMCT-GAIPWAGLSAE 376
++ H P AW P F S SD W FG TL EM T G PW GL+
Sbjct: 285 VMQEHRKVPFAWCAPESLKTRTF-------SHASDTWMFGVTLWEMFTYGQEPWIGLNGS 337
Query: 377 EIYRQVVKAKKQPPQYASVVGGGIPRELWKMIGECLQFKPSKRPTFNAM 425
+I ++ K ++ P+ P++++ ++ +C KP RPTF A+
Sbjct: 338 QILHKIDKEGERLPRPED-----CPQDIYNVMVQCWAHKPEDRPTFVAL 381
>MATK_MOUSE (P41242) Megakaryocyte-associated tyrosine-protein
kinase (EC 2.7.1.112) (Tyrosine-protein kinase CTK)
(Protein kinase NTK)
Length = 505
Score = 77.0 bits (188), Expect = 1e-13
Identities = 82/305 (26%), Positives = 132/305 (42%), Gaps = 49/305 (16%)
Query: 141 QDLKLVRRIGEGRRAGVEMWSAVIGGGRCKHQVAVKKVVLNEGMDLDWMLGKLEDLRRTS 200
Q L L +IGEG + AV+ G +VAVK + D+ E T
Sbjct: 231 QHLTLGAQIGEGE------FGAVLQGEYLGQKVAVKNIKC----DVTAQAFLDETAVMTK 280
Query: 201 MWCRNVCTFHGAMKVDEGLCLVMDKCFGSVQSEMLRNEGR--LTLEQVLRYGADIARGVV 258
+ RN+ G + + GL +VM+ LR GR ++ Q+L++ +A G+
Sbjct: 281 LQHRNLVRLLGVI-LHHGLYIVMEHVSKGNLVNFLRTRGRALVSTSQLLQFALHVAEGME 339
Query: 259 ELHAAGVVCMSLKPSNLLLDANGHAVVSDYGLATILKKPSCWKARPECDSAKIHSCMECI 318
L + +V L N+L+ + A VSD+GLA +K DS++
Sbjct: 340 YLESKKLVHRDLAARNILVSEDLVAKVSDFGLAKAERK--------GLDSSR-------- 383
Query: 319 MLSPHYTAPEAWEPVKKSLNLFWDDGIGISPESDAWSFGCTLVEMCT-GAIPWAGLSAEE 377
L +TAPEA + + S +SD WSFG L E+ + G P+ +S +E
Sbjct: 384 -LPVKWTAPEALKNGR------------FSSKSDVWSFGVLLWEVFSYGRAPYPKMSLKE 430
Query: 378 IYRQVVKAKKQPPQYASVVGGGIPRELWKMIGECLQFKPSKRPTFNAMLAIFLRHLQEIP 437
+ V K + P G P + ++G C + +P++RP F ++ R L+ +
Sbjct: 431 VSEAVEKGYRMEPP------DGCPGSVHTLMGSCWEAEPARRPPFRKIVEKLGRELRSVG 484
Query: 438 RSPPA 442
S PA
Sbjct: 485 VSAPA 489
>ACK1_HUMAN (Q07912) Activated CDC42 kinase 1 (EC 2.7.1.112) (ACK-1)
Length = 1036
Score = 77.0 bits (188), Expect = 1e-13
Identities = 71/289 (24%), Positives = 122/289 (41%), Gaps = 35/289 (12%)
Query: 141 QDLKLVRRIGEGRRAGVEM--WSAVIGGGRCKHQVAVKKVVLNEGMDLDWMLGKLEDLRR 198
+DL+L+ ++G+G V W A G +K VL++ +D + ++ +
Sbjct: 124 KDLRLLEKLGDGSFGVVRRGEWDAPSGKTVSVAVKCLKPDVLSQPEAMDDFIREVNAMH- 182
Query: 199 TSMWCRNVCTFHGAMKVDEGLCLVMDKCFGSVQSEMLRNEGRLTLEQVLRYGADIARGVV 258
S+ RN+ +G + + GS+ + +++G L + RY +A G+
Sbjct: 183 -SLDHRNLIRLYGVVLTPPMKMVTELAPLGSLLDRLRKHQGHFLLGTLSRYAVQVAEGMG 241
Query: 259 ELHAAGVVCMSLKPSNLLLDANGHAVVSDYGLATILKKPSCWKARPECDSAKIHSCMECI 318
L + + L NLLL + D+GL +A P+ D +
Sbjct: 242 YLESKRFIHRDLAARNLLLATRDLVKIGDFGL---------MRALPQND--------DHY 284
Query: 319 MLSPHYTAPEAW-EPVKKSLNLFWDDGIGISPESDAWSFGCTLVEMCT-GAIPWAGLSAE 376
++ H P AW P F S SD W FG TL EM T G PW GL+
Sbjct: 285 VMQEHRKVPFAWCAPESLKTRTF-------SHASDTWMFGVTLWEMFTYGQEPWIGLNGS 337
Query: 377 EIYRQVVKAKKQPPQYASVVGGGIPRELWKMIGECLQFKPSKRPTFNAM 425
+I ++ K ++ P+ P++++ ++ +C KP RPTF A+
Sbjct: 338 QILHKIDKEGERLPRPED-----CPQDIYNVMVQCWAHKPEDRPTFVAL 381
>K6A6_HUMAN (Q9UK32) Ribosomal protein S6 kinase alpha 6 (EC
2.7.1.37) (S6K-alpha 6) (90 kDa ribosomal protein S6
kinase 6) (p90-RSK 6) (Ribosomal S6 kinase 4) (RSK-4)
(pp90RSK4)
Length = 745
Score = 76.6 bits (187), Expect = 2e-13
Identities = 59/201 (29%), Positives = 87/201 (42%), Gaps = 26/201 (12%)
Query: 206 VCTFHGAMKVDEGLCLVMDKCFGSVQSEMLRNEGRLTLEQVLRYGADIARGVVELHAAGV 265
+ H A + + L L++D G L E T E V Y A++A + LH G+
Sbjct: 135 IVKLHYAFQTEGKLYLILDFLRGGDVFTRLSKEVLFTEEDVKFYLAELALALDHLHQLGI 194
Query: 266 VCMSLKPSNLLLDANGHAVVSDYGLATILKKPSCWKARPECDSAKIHSCMECIMLSPHYT 325
V LKP N+LLD GH ++D+GL+ K + + C + Y
Sbjct: 195 VYRDLKPENILLDEIGHIKLTDFGLS---------KESVDQEKKAYSFCG-----TVEYM 240
Query: 326 APEAWEPVKKSLNLFWDDGIGISPESDAWSFGCTLVEMCTGAIPWAGLSAEEIYRQVVKA 385
APE V + G S +D WS+G + EM TG +P+ G E ++KA
Sbjct: 241 APEV---VNRR---------GHSQSADWWSYGVLMFEMLTGTLPFQGKDRNETMNMILKA 288
Query: 386 KKQPPQYASVVGGGIPRELWK 406
K PQ+ S + R L+K
Sbjct: 289 KLGMPQFLSAEAQSLLRMLFK 309
Score = 37.7 bits (86), Expect = 0.095
Identities = 59/230 (25%), Positives = 90/230 (38%), Gaps = 48/230 (20%)
Query: 253 IARGVVELHAAGVVCMSLKPSNLL-LDANGHA---VVSDYGLATILKKPSCWKARPECDS 308
I++ V LH GVV LKPSN+L +D + A + D+G A L+ +
Sbjct: 527 ISKTVDYLHCQGVVHRDLKPSNILYMDESASADSIRICDFGFAKQLRGEN---------- 576
Query: 309 AKIHSCMECIMLSPHYTAPEAWEPVKKSLNLFWDDGIGISPESDAWSFGCTLVEMCTGAI 368
++L+P YTA V G D WS G M G
Sbjct: 577 --------GLLLTPCYTANFVAPEVLMQQ--------GYDAACDIWSLGVLFYTMLAGYT 620
Query: 369 PWA---GLSAEEIYRQVVKAKKQPPQYASVVGG---GIPRELWKMIGECLQFKPSKRPTF 422
P+A + EEI ++ K S+ GG I ++ L P +R T
Sbjct: 621 PFANGPNDTPEEILLRIGNGK------FSLSGGNWDNISDGAKDLLSHMLHMDPHQRYTA 674
Query: 423 NAMLA-IFLRHLQEIPRSPPASPD-NDLVKGSV----SNVTEASPVPELE 466
+L ++ H ++P P D + +VKG++ S +T + P LE
Sbjct: 675 EQILKHSWITHRDQLPNDQPKRNDVSHVVKGAMVATYSALTHKTFQPVLE 724
>ACK2_BOVIN (O02742) Activated CDC42 kinase 2 (EC 2.7.1.112) (ACK-2)
Length = 747
Score = 76.3 bits (186), Expect = 2e-13
Identities = 72/289 (24%), Positives = 120/289 (40%), Gaps = 35/289 (12%)
Query: 141 QDLKLVRRIGEGRRAGVEM--WSAVIGGGRCKHQVAVKKVVLNEGMDLDWMLGKLEDLRR 198
+DL L ++G+G V W A G +K VL++ +D + ++ +
Sbjct: 124 KDLHLFEKLGDGSFGVVRRGEWDAPSGKTVSVAVKCLKPDVLSQPEAMDDFIREVNAMH- 182
Query: 199 TSMWCRNVCTFHGAMKVDEGLCLVMDKCFGSVQSEMLRNEGRLTLEQVLRYGADIARGVV 258
S+ RN+ +G + + GS+ + +++G L + RY +A G+
Sbjct: 183 -SLDHRNLIRLYGVVLTPPMKMVTELAPLGSLLDRLRKHQGHFLLGTLSRYAVQVAEGMG 241
Query: 259 ELHAAGVVCMSLKPSNLLLDANGHAVVSDYGLATILKKPSCWKARPECDSAKIHSCMECI 318
L A + L NLLL + D+GL +A P+ D +
Sbjct: 242 YLEAKRFIHRDLAARNLLLATRDLVKIGDFGL---------MRALPQND--------DHY 284
Query: 319 MLSPHYTAPEAW-EPVKKSLNLFWDDGIGISPESDAWSFGCTLVEMCT-GAIPWAGLSAE 376
++ H P AW P F S SD W FG TL EM T G PW GL+
Sbjct: 285 VMQEHRKVPFAWCAPESLKTRTF-------SHASDTWMFGVTLWEMFTYGQEPWIGLNGS 337
Query: 377 EIYRQVVKAKKQPPQYASVVGGGIPRELWKMIGECLQFKPSKRPTFNAM 425
+I ++ K ++ P+ P++++ ++ +C KP RPTF A+
Sbjct: 338 QILHKIDKEGERLPRPED-----CPQDIYNVMVQCWAHKPEDRPTFVAL 381
>PK2_DICDI (P28178) Protein kinase 2 (EC 2.7.1.-)
Length = 479
Score = 75.9 bits (185), Expect = 3e-13
Identities = 57/209 (27%), Positives = 91/209 (43%), Gaps = 32/209 (15%)
Query: 206 VCTFHGAMKVDEGLCLVMDKCFGSVQSEMLRNEGRLTLEQVLRYGADIARGVVELHAAGV 265
+ H A + + L +V+D G L+ EGR + +V Y A+I + LH +
Sbjct: 213 IVNLHYAFQTKDKLYMVLDFVNGGELFFHLKREGRFSEPRVKIYAAEIVSALDHLHKQDI 272
Query: 266 VCMSLKPSNLLLDANGHAVVSDYGLATILKKPSCWKARPECDSAKIHSCMECIMLSPHYT 325
V LKP N+LLD+ GH ++D+GL+ + E C +P Y
Sbjct: 273 VYRDLKPENILLDSEGHICITDFGLS----------KKIETTDGTFTFCG-----TPEYL 317
Query: 326 APEAWEPVKKSLNLFWDDGIGISPESDAWSFGCTLVEMCTGAIPWAGLSAEEIYRQVVKA 385
APE +G G D WS G L EM TG P+ + +Y++++
Sbjct: 318 APEVL------------NGHGHGCAVDWWSLGTLLYEMLTGLPPFYSQNVSTMYQKILNG 365
Query: 386 KKQPPQY-----ASVVGGGIPRELWKMIG 409
+ + P Y S++ G + RE+ K +G
Sbjct: 366 ELKIPTYISPEAKSLLEGLLTREVDKRLG 394
>MATK_RAT (P41243) Megakaryocyte-associated tyrosine-protein kinase
(EC 2.7.1.112) (Tyrosine-protein kinase CTK) (Protein
kinase BATK)
Length = 467
Score = 75.9 bits (185), Expect = 3e-13
Identities = 79/305 (25%), Positives = 130/305 (41%), Gaps = 48/305 (15%)
Query: 141 QDLKLVRRIGEGRRAGVEMWSAVIGGGRCKHQVAVKKVVLNEGMDLDWMLGKLEDLRRTS 200
Q L L +IGEG + AV+ G +VAVK + D+ E T
Sbjct: 192 QHLTLGAQIGEGE------FGAVLQGEYLGQKVAVKNIKC----DVTAQAFLDETAVMTK 241
Query: 201 MWCRNVCTFHGAMKVDEGLCLVMDKCFGSVQSEMLRNEGR--LTLEQVLRYGADIARGVV 258
+ RN+ G + + GL +VM+ LR GR ++ Q+L++ +A G+
Sbjct: 242 LQHRNLVRLLGVI-LHHGLYIVMEHVSKGNLVNFLRTRGRALVSTSQLLQFALHVAEGME 300
Query: 259 ELHAAGVVCMSLKPSNLLLDANGHAVVSDYGLATILKKPSCWKARPECDSAKIHSCMECI 318
L + +V L N+L+ + A VSD+GLA A++ ++
Sbjct: 301 YLESKKLVHRDLAARNILVSEDLVAKVSDFGLA----------------KAELRKGLDSS 344
Query: 319 MLSPHYTAPEAWEPVKKSLNLFWDDGIGISPESDAWSFGCTLVEMCT-GAIPWAGLSAEE 377
L +TAPEA + + S +SD WSFG L E+ + G P+ +S +E
Sbjct: 345 RLPVKWTAPEALKNGR------------FSSKSDVWSFGVLLWEVFSYGRAPYPKMSLKE 392
Query: 378 IYRQVVKAKKQPPQYASVVGGGIPRELWKMIGECLQFKPSKRPTFNAMLAIFLRHLQEIP 437
+ V K + P P + ++G C + +PS+RP F ++ R L+ +
Sbjct: 393 VSEAVEKGYRMEPP------DSCPGPVHTLMGSCWEAEPSRRPPFRKIVEKLGRELRSVG 446
Query: 438 RSPPA 442
+ PA
Sbjct: 447 VAAPA 451
>KPC4_DROME (P83099) Putative protein kinase C, delta type homolog
(EC 2.7.1.37)
Length = 643
Score = 75.9 bits (185), Expect = 3e-13
Identities = 62/233 (26%), Positives = 98/233 (41%), Gaps = 33/233 (14%)
Query: 175 VKKVVLNEGMDLDWMLGKLEDLR---RTSMWCRNVCTFHGAMKVDEGLCLVMDKCFGSVQ 231
+KK V+ E D+D L + + L + C CTF + + L VM+ G
Sbjct: 346 LKKDVVLEDDDVDSTLIERKVLALGTKHPYLCHLFCTF----QTESHLFFVMEYLNGGDL 401
Query: 232 SEMLRNEGRLTLEQVLRYGADIARGVVELHAAGVVCMSLKPSNLLLDANGHAVVSDYGLA 291
++ GR + E+ YGA+I G+ LH G++ LK N+LLD GH ++D+G+
Sbjct: 402 MFHIQESGRFSEERARFYGAEIISGLKFLHKKGIIYRDLKLDNVLLDYEGHVRIADFGMC 461
Query: 292 TILKKPSCWKARPECDSAKIHSCMECIMLSPHYTAPEAWEPVKKSLNLFWDDGIGISPES 351
+ + + +P Y APE + K + N+ W
Sbjct: 462 KL--------------QIYLDKTADSFCGTPDYMAPEIIKGEKYNQNVDW---------- 497
Query: 352 DAWSFGCTLVEMCTGAIPWAGLSAEEIYRQVVKAKKQPPQYASVVGGGIPREL 404
WSFG L EM G P++G +E++ + P Y S GI + L
Sbjct: 498 --WSFGVLLYEMLIGQSPFSGCDEDELFWSICNEIPWFPVYISAEATGILKGL 548
>PLK3_CAEEL (Q20845) Serine/threonine-protein kinase plk-3 (EC
2.7.1.37) (Polo-like kinase 3)
Length = 615
Score = 75.5 bits (184), Expect = 4e-13
Identities = 83/345 (24%), Positives = 138/345 (39%), Gaps = 46/345 (13%)
Query: 169 CKHQVAVK---KVVLNEGMDLDWMLGKLEDLRRTSMWCRNVCTFHGAMKVDEGLCLVMDK 225
C ++AVK KV+L + + + ++E R+ S RN+ FH + + + ++
Sbjct: 57 CNDRLAVKVVPKVILLKSTAREKLTREVEIHRQLSH--RNIVQFHHFFEDSQNVYFTLEL 114
Query: 226 CFGSVQSEMLRNEGRLTLEQVLRYGADIARGVVELHAAGVVCMSLKPSNLLLDANGHAVV 285
C + E+ + G LT + Y +A GV LH ++ LK NL L+ + +
Sbjct: 115 CSKNSLMELNKQRGPLTEHEARFYTIQVAEGVKHLHNLQIIHRDLKLGNLFLNEHLQVKI 174
Query: 286 SDYGLATILKKPSCWKARPECDSAKIHSCMECIMLSPHYTAPEAWEPVKKSLNLFWDDGI 345
D+GLAT +K R +P+Y APE
Sbjct: 175 GDFGLATFCEKNEKKMTRGG---------------TPNYIAPEVLNET------------ 207
Query: 346 GISPESDAWSFGCTLVEMCTGAIPWAGLSAEEIYRQVVKAKKQPPQYASVVGGGIPRELW 405
G + E D W+ GC L + G+ P+ +E Y ++ P+ AS + R L
Sbjct: 208 GHAFEVDIWAIGCILYVLLFGSPPFESRRVQETYVRIKNNDYVVPENASPTANRLIRSL- 266
Query: 406 KMIGECLQFKPSKRPTFNAMLAIFLRHLQEIPRSPPASPDNDLVKGSVSNVTEASPV-PE 464
L P +RPT A+L P PP + V +PV P
Sbjct: 267 ------LDPVPDRRPTAEAVLLDQFFKTTIEPTYPPVHQQLH-KEQDVKYFAPINPVLPH 319
Query: 465 LEIPQDPNRLHRLVSEGDVTGVRDFLAKAASENESNFISSLLEAQ 509
+E P P +++ V+ + + +R F+ +E S+F L + Q
Sbjct: 320 VEEPISP--IYQEVANEETSEIRRFV---KTEQASSFGDELSQLQ 359
>PKAA_STRCO (P54739) Serine/threonine protein kinase pkaA (EC
2.7.1.37)
Length = 543
Score = 75.5 bits (184), Expect = 4e-13
Identities = 73/262 (27%), Positives = 106/262 (39%), Gaps = 42/262 (16%)
Query: 167 GRCKHQVAVKKVVLNEGMDLDWMLGKLEDLRRTSMWCR----NVCTFHGAMKVDEGLCLV 222
G+ VA+K + D D ++ LR S+ R N+ + E L LV
Sbjct: 39 GQPGETVAIKVLKEELASDADIVM---RFLRERSVLLRLTHPNIVRVRDLVVEGELLALV 95
Query: 223 MDKCFGSVQSEMLRNEGRLTLEQVLRYGADIARGVVELHAAGVVCMSLKPSNLLLDANG- 281
MD G LR G LT A IA + HA GVV LKP+N+LL G
Sbjct: 96 MDLIDGPDLHRYLRENGPLTPVAAALLTAQIADALAASHADGVVHRDLKPANVLLKQTGG 155
Query: 282 --HAVVSDYGLATILKKPSCWKARPECDSAKIHSCMECIMLSPHYTAPEAWEPVKKSLNL 339
H +++D+G+A + P + + +P Y APE+ E
Sbjct: 156 EMHPMLTDFGIARLADSPGLTRTHE-------------FVGTPAYVAPESAE-------- 194
Query: 340 FWDDGIGISPESDAWSFGCTLVEMCTGAIPWAGLSAEEIYRQVVKAKKQPPQYASVVGGG 399
G + D + G L E+ TG P+ G SA E+ Q + A+ + P
Sbjct: 195 ----GRPQTSAVDVYGAGILLYELVTGRPPFGGGSALEVLHQHLSAEPRRP-------ST 243
Query: 400 IPRELWKMIGECLQFKPSKRPT 421
+P LW +I CL+ P RP+
Sbjct: 244 VPDPLWTVIERCLRKNPDDRPS 265
>PKAB_STRCO (P54740) Serine/threonine protein kinase pkaB (EC
2.7.1.37)
Length = 417
Score = 73.6 bits (179), Expect = 2e-12
Identities = 62/211 (29%), Positives = 91/211 (42%), Gaps = 44/211 (20%)
Query: 219 LCLVMDKCFGSVQSEMLRNEGRLTLEQVLRYGADIARGVVELHAAGVVCMSLKPSNLLLD 278
L LVMD G+ L E RL E + AD+A G+ HAAGVV +KP N+LLD
Sbjct: 80 LALVMDLVRGTDLRTRLDRERRLAPEAAVAVVADVADGLAAAHAAGVVHRDVKPENVLLD 139
Query: 279 ANG--------HAVVSDYGLATILKKPSCWKARPECDSAKIHSCMECIMLSPHYTAPEAW 330
G A+++D+G+A ++ P +A I+ +P Y APE
Sbjct: 140 MQGPLGPGGSHPALLTDFGVAKLIDTPRRTRATK-------------IIGTPDYLAPEIV 186
Query: 331 EPVKKSLNLFWDDGIGISPES--DAWSFGCTLVEMCTGAIPWAGLSAEEIYRQVVKAKKQ 388
E G+ P + D ++ L E+ G P+ G + R+ V
Sbjct: 187 E--------------GLPPRAAVDIYALATVLYELLAGFTPFGGGHPGAVLRRHVTETVV 232
Query: 389 PPQYASVVGGGIPRELWKMIGECLQFKPSKR 419
P GIP ELW+++ +CL P+ R
Sbjct: 233 PLP-------GIPDELWQLLVQCLAKAPASR 256
>BCK1_YEAST (Q01389) Serine/threonine-protein kinase BCK1/SLK1/SSP31
(EC 2.7.1.37)
Length = 1478
Score = 73.6 bits (179), Expect = 2e-12
Identities = 57/232 (24%), Positives = 94/232 (39%), Gaps = 43/232 (18%)
Query: 205 NVCTFHGAMKVDEGLCLVMDKCFGSVQSEMLRNEGRLTLEQVLRYGADIARGVVELHAAG 264
N+ + G + L ++ G ++R GR + + +G+ LH+ G
Sbjct: 1239 NIVQYLGFENKNNIYSLFLEYVAGGSVGSLIRMYGRFDEPLIKHLTTQVLKGLAYLHSKG 1298
Query: 265 VVCMSLKPSNLLLDANGHAVVSDYGLATILKKPSCWKARPECDSAKIHSCMECIML-SPH 323
++ +K NLLLD +G +SD+G++ S I+S + M +
Sbjct: 1299 ILHRDMKADNLLLDQDGICKISDFGISR--------------KSKDIYSNSDMTMRGTVF 1344
Query: 324 YTAPEAWEPVKKSLNLFWDDGIGISPESDAWSFGCTLVEMCTGAIPWAGLSAEEIYRQVV 383
+ APE D G S + D WS GC ++EM G PW+ L ++
Sbjct: 1345 WMAPE-----------MVDTKQGYSAKVDIWSLGCIVLEMFAGKRPWSNLEVVAAMFKIG 1393
Query: 384 KAKKQPPQYASVVGGGIPRELWKMIGE--------CLQFKPSKRPTFNAMLA 427
K+K PP IP + +I + C + P KRPT N +L+
Sbjct: 1394 KSKSAPP---------IPEDTLPLISQIGRNFLDACFEINPEKRPTANELLS 1436
Database: sprot
Posted date: Nov 25, 2004 10:54 AM
Number of letters in database: 59,974,054
Number of sequences in database: 164,201
Lambda K H
0.318 0.135 0.415
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 81,157,521
Number of Sequences: 164201
Number of extensions: 3609830
Number of successful extensions: 19035
Number of sequences better than 10.0: 1874
Number of HSP's better than 10.0 without gapping: 1055
Number of HSP's successfully gapped in prelim test: 823
Number of HSP's that attempted gapping in prelim test: 14679
Number of HSP's gapped (non-prelim): 3344
length of query: 652
length of database: 59,974,054
effective HSP length: 117
effective length of query: 535
effective length of database: 40,762,537
effective search space: 21807957295
effective search space used: 21807957295
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 69 (31.2 bits)
Medicago: description of AC126006.5