BLASTP 2.2.2 [Dec-14-2001]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= AC124972.13 - phase: 0 
         (935 letters)

Database: sprot 
           164,201 sequences; 59,974,054 total letters

Searching..................................................done

                                                                   Score     E
Sequences producing significant alignments:                        (bits)  Value

AGOL_ARATH (Q9SJK3) Argonaute-like protein At2g27880                  485  e-136
PINH_ARATH (Q9XGW1) PINHEAD protein (ZWILLE protein)                  476  e-133
AGO1_ARATH (O04379) Argonaute protein                                 464  e-130
I2C2_RAT (Q9QZ81) Eukaryotic translation initiation factor 2C 2 ...   380  e-105
I2C2_MOUSE (Q8CJG0) Eukaryotic translation initiation factor 2C ...   379  e-104
I2C2_RABIT (O77503) Eukaryotic translation initiation factor 2C ...   378  e-104
I2C4_HUMAN (Q9HCK5) Eukaryotic translation initiation factor 2C ...   376  e-103
I2C2_HUMAN (Q9UKV8) Eukaryotic translation initiation factor 2C ...   370  e-102
I2C1_HUMAN (Q9UL18) Eukaryotic translation initiation factor 2C ...   365  e-100
I2C4_MOUSE (Q8CJF8) Eukaryotic translation initiation factor 2C ...   364  e-100
I2C3_MOUSE (Q8CJF9) Eukaryotic translation initiation factor 2C ...   363  1e-99
I2C3_HUMAN (Q9H9G7) Eukaryotic translation initiation factor 2C ...   362  3e-99
I2C1_MOUSE (Q8CJG1) Eukaryotic translation initiation factor 2C ...   357  1e-97
AGO1_SCHPO (O74957) Cell cycle control protein ago1 (RNA interfe...   318  3e-86
YO43_CAEEL (P34681) Hypothetical protein ZK757.3 in chromosome III    258  5e-68
AGO2_DROME (Q9VUQ5) Argonaute 2 protein                               251  5e-66
PIWI_BRARE (Q8UVX0) Piwi protein                                      158  6e-38
PIWI_DROME (Q9VKM1) Piwi protein                                      140  2e-32
GCC7_CAEEL (Q21770) Germ cell expressed protein R06C7.1                94  1e-18
YQ53_CAEEL (Q09249) Hypothetical protein C16C10.3 in chromosome III    92  8e-18

>AGOL_ARATH (Q9SJK3) Argonaute-like protein At2g27880
          Length = 997

 Score =  485 bits (1249), Expect = e-136
 Identities = 325/907 (35%), Positives = 475/907 (51%), Gaps = 102/907 (11%)

Query: 70  RRGLGSKGAKLPLLTNHFKVNVTNTDGYFFQYSVALFYEDGRPVEGKGAGRKILDRVQET 129
           R G G+ G K+ +  NHF V V + D Y +  S+         V  K   R ++  + + 
Sbjct: 150 RPGRGTLGKKVMVRANHFLVQVADRDLYHYDVSI------NPEVISKTVNRNVMKLLVKN 203

Query: 130 Y-GSELNGKDLAYDGEKTLFTIGSLAQNKLEFTVVLEDVTSNRNNGNASPDGHGSPNDTD 188
           Y  S L GK  AYDG K+L+T G L  +  EF V L +  ++ ++G   P          
Sbjct: 204 YKDSHLGGKSPAYDGRKSLYTAGPLPFDSKEFVVNLAEKRADGSSGKDRP---------- 253

Query: 189 RKRLKKSHRSKTYKVEISFASKIPLQAIANALKGHETENYQEAIRVLDIILRQHAAKQGC 248
                       +KV +   +   L  +   L   + E   + I+VLD++LR   +    
Sbjct: 254 ------------FKVAVKNVTSTDLYQLQQFLDRKQREAPYDTIQVLDVVLRDKPSND-Y 300

Query: 249 LLVRQNFFHNDPKNFTDVGGGVLG-----CRGLHSSFRTTQSGLSLNIDVSTTMIVHPGP 303
           + V ++FFH         G G LG      RG   S R TQ GLSLNIDVS      P  
Sbjct: 301 VSVGRSFFHTSLGKDARDGRGELGDGIEYWRGYFQSLRLTQMGLSLNIDVSARSFYEPIV 360

Query: 304 VVDFLIANQNVRD---PF-SLDWNKAKRTLKNLRITTSPTN--QEYKITGLSEMPCKDQL 357
           V DF+    N+RD   P    D  K K+ L+ L++     N  +  KI+G+S +P ++  
Sbjct: 361 VTDFISKFLNIRDLNRPLRDSDRLKVKKVLRTLKVKLLHWNCTKSAKISGISSLPIRELR 420

Query: 358 FTLKKRGAVPGEDDTEEITVYDYFVNRRKISLQYSADLPCINVGKPKRPTFVPVELCSLV 417
           FTL         +D  E TV  YF  +    ++Y A LP I  G   RP ++P+ELC + 
Sbjct: 421 FTL---------EDKSEKTVVQYFAEKYNYRVKYQA-LPAIQTGSDTRPVYLPMELCQID 470

Query: 418 SLQRYTKALSTLQRSSLVEKSRQKPQERMRVLTDALKTSDYGSEPMLRNCGISITSGFTQ 477
             QRYTK L+  Q ++L++ + Q+P +R   + + +  ++Y  + + +  G+S+T+    
Sbjct: 471 EGQRYTKRLNEKQVTALLKATCQRPPDRENSIKNLVVKNNYNDD-LSKEFGMSVTTQLAS 529

Query: 478 VDGRVLQAPRLKF---GNGEDFNPRNGRWNFNNKKIVQPVKIEKWAVVNFSARCDVRGLV 534
           ++ RVL  P LK+   G  +  NPR G+WN  +KK+V   K+  W  V+FS R D RGL 
Sbjct: 530 IEARVLPPPMLKYHDSGKEKMVNPRLGQWNMIDKKMVNGAKVTSWTCVSFSTRID-RGLP 588

Query: 535 RDLIKCGGMKGIHVEQPFDCFEENGQFRRAPPLVRVEKMFEHVQSKL-------PGAPKF 587
           ++   C  + G+       C  +  +F+  P +  +    EH++  L       PG  + 
Sbjct: 589 QEF--CKQLIGM-------CVSKGMEFKPQPAIPFISCPPEHIEEALLDIHKRAPGL-QL 638

Query: 588 LLCLLSERKNSDLYGPWKKKNLAEFGIVTQCIAPTRVND---QYLTNVLLKINAKLGGMN 644
           L+ +L +   S  YG  K+    E GIV+QC  P +VN    QY+ NV LKIN K GG N
Sbjct: 639 LIVILPDVTGS--YGKIKRICETELGIVSQCCQPRQVNKLNKQYMENVALKINVKTGGRN 696

Query: 645 SLLGVEHSPSIPIVSKAPTLILGMDVSHGSPGQTEIPSIAAVVSSRQWPLISKYRACVRT 704
           ++L      +IP+++  PT+I+G DV+H  PG+   PSIAAVV+S  WP I+KYR  V  
Sbjct: 697 TVLNDAIRRNIPLITDRPTIIMGADVTHPQPGEDSSPSIAAVVASMDWPEINKYRGLVSA 756

Query: 705 QGAKVEMIDNLFKPVSDTE----DEGIIRELLIDFYNSSGNRKPDNIIIFRDGVSESQFN 760
           Q  + E+I +L+K V D +      G+IRE  I F  ++G + P  II +RDGVSE QF+
Sbjct: 757 QAHREEIIQDLYKLVQDPQRGLVHSGLIREHFIAFRRATG-QIPQRIIFYRDGVSEGQFS 815

Query: 761 QVLNIELSQIIEACKFLDEKWNPKFLVIVAQKNHHTKFF--QPGSPD------NVPPGTV 812
           QVL  E++ I +AC  L E + P+   ++ QK HHT+ F  Q G+ D      N+ PGTV
Sbjct: 816 QVLLHEMTAIRKACNSLQENYVPRVTFVIVQKRHHTRLFPEQHGNRDMTDKSGNIQPGTV 875

Query: 813 VDNKICHPRNYDFYMCAHAGMIGTSRPTHYHVLLDEIGFSPDDLQELVHSLSYVYQRSTT 872
           VD KICHP  +DFY+ +HAG+ GTSRP HYHVLLDE GF+ D LQ L ++L Y Y R T 
Sbjct: 876 VDTKICHPNEFDFYLNSHAGIQGTSRPAHYHVLLDENGFTADQLQMLTNNLCYTYARCTK 935

Query: 873 AISVVAPICYAHLAASQVGQFMKFEDKSETSSSHGGSGRDINASP-----IPQLPKLMDS 927
           ++S+V P  YAHLAA +   +M      E+  S GGS R  +++      I QLP + D+
Sbjct: 936 SVSIVPPAYYAHLAAFRARYYM------ESEMSDGGSSRSRSSTTGVGQVISQLPAIKDN 989

Query: 928 VCNSMFF 934
           V   MF+
Sbjct: 990 VKEVMFY 996


>PINH_ARATH (Q9XGW1) PINHEAD protein (ZWILLE protein)
          Length = 988

 Score =  476 bits (1224), Expect = e-133
 Identities = 321/948 (33%), Positives = 485/948 (50%), Gaps = 104/948 (10%)

Query: 39  PPPP----------IVPADIEPIKIEPQIVKKKLPTKVPMARRGLGSKGAKLPLLTNHFK 88
           PPPP              +I  +  + Q+  +K     P  R G G+ G K  +  NHF 
Sbjct: 92  PPPPSQTTSSAVSVATAGEIVAVNHQMQMGVRKNSNFAP--RPGFGTLGTKCIVKANHFL 149

Query: 89  VNVTNTDGYFFQYSVALFYEDGRPVEGKGAGRKILDRVQETYGSELNGKDL-AYDGEKTL 147
            ++   D    QY V +  E    V  K   R I+  +   Y     G+ L AYDG K+L
Sbjct: 150 ADLPTKD--LNQYDVTITPE----VSSKSVNRAIIAELVRLYKESDLGRRLPAYDGRKSL 203

Query: 148 FTIGSLAQNKLEFTVVLEDVTSNRNNGNASPDGHGSPNDTDRKRLKKSHRSKTYKVEISF 207
           +T G L     EF+V + D      NG                      R ++YKV I F
Sbjct: 204 YTAGELPFTWKEFSVKIVDEDDGIING--------------------PKRERSYKVAIKF 243

Query: 208 ASKIPLQAIANALKGHETENYQEAIRVLDIILRQHAAKQGCLLVRQNFFHNDPKNFTDVG 267
            ++  +  +   L G   +  QEA+++LDI+LR+ + K+ C + R +FF  D K    +G
Sbjct: 244 VARANMHHLGEFLAGKRADCPQEAVQILDIVLRELSVKRFCPVGR-SFFSPDIKTPQRLG 302

Query: 268 GGVLGCRGLHSSFRTTQSGLSLNIDVSTTMIVHPGPVVDF---LIANQNVRDPFS-LDWN 323
            G+    G + S R TQ GLSLNID+++   + P PV++F   L+    +  P S  D  
Sbjct: 303 EGLESWCGFYQSIRPTQMGLSLNIDMASAAFIEPLPVIEFVAQLLGKDVLSKPLSDSDRV 362

Query: 324 KAKRTLKNLRITTSP---TNQEYKITGLSEMPCKDQLFTLKKRGAVPGEDDTEEITVYDY 380
           K K+ L+ +++  +      ++Y++ GL+  P ++ +F        P +++    +V +Y
Sbjct: 363 KIKKGLRGVKVEVTHRANVRRKYRVAGLTTQPTRELMF--------PVDENCTMKSVIEY 414

Query: 381 FVNRRKISLQYSADLPCINVGKPKRPTFVPVELCSLVSLQRYTKALSTLQRSSLVEKSRQ 440
           F      ++Q++  LPC+ VG  K+ +++P+E C +V  QRYTK L+  Q ++L++ + Q
Sbjct: 415 FQEMYGFTIQHT-HLPCLQVGNQKKASYLPMEACKIVEGQRYTKRLNEKQITALLKVTCQ 473

Query: 441 KPQERMRVLTDALKTSDYGSEPMLRNCGISITSGFTQVDGRVLQAPRLKF---GNGEDFN 497
           +P++R   +   ++ + Y  +P  +  G++I+     V+ R+L AP LK+   G  +D  
Sbjct: 474 RPRDRENDILRTVQHNAYDQDPYAKEFGMNISEKLASVEARILPAPWLKYHENGKEKDCL 533

Query: 498 PRNGRWNFNNKKIVQPVKIEKWAVVNFSARCD---VRGLVRDLIKCGGMKGIHVEQPFDC 554
           P+ G+WN  NKK++  + + +WA VNFS        RG   +L +   + G+        
Sbjct: 534 PQVGQWNMMNKKMINGMTVSRWACVNFSRSVQENVARGFCNELGQMCEVSGMEFNP---- 589

Query: 555 FEENGQFRRAPPLVRVEKMFEHV----QSKLPGAPKFLLCLLSERKNSDLYGPWKKKNLA 610
            E       A P  +VEK  +HV     +K  G    LL  +    N  LYG  K+    
Sbjct: 590 -EPVIPIYSARP-DQVEKALKHVYHTSMNKTKGKELELLLAILPDNNGSLYGDLKRICET 647

Query: 611 EFGIVTQCIAPT---RVNDQYLTNVLLKINAKLGGMNSLLGVEHSPSIPIVSKAPTLILG 667
           E G+++QC       +++ QYL NV LKIN K+GG N++L    S  IP+VS  PT+I G
Sbjct: 648 ELGLISQCCLTKHVFKISKQYLANVSLKINVKMGGRNTVLVDAISCRIPLVSDIPTIIFG 707

Query: 668 MDVSHGSPGQTEIPSIAAVVSSRQWPLISKYRACVRTQGAKVEMIDNLFK----PVSDTE 723
            DV+H   G+   PSIAAVV+S+ WP ++KY   V  Q  + E+I +L+K    PV  T 
Sbjct: 708 ADVTHPENGEESSPSIAAVVASQDWPEVTKYAGLVCAQAHRQELIQDLYKTWQDPVRGTV 767

Query: 724 DEGIIRELLIDFYNSSGNRKPDNIIIFRDGVSESQFNQVLNIELSQIIEACKFLDEKWNP 783
             G+IR+LLI F  ++G +KP  II +RDGVSE QF QVL  EL  I +AC  L+  + P
Sbjct: 768 SGGMIRDLLISFRKATG-QKPLRIIFYRDGVSEGQFYQVLLYELDAIRKACASLEPNYQP 826

Query: 784 KFLVIVAQKNHHTKFFQPGSPD--------NVPPGTVVDNKICHPRNYDFYMCAHAGMIG 835
               IV QK HHT+ F     D        N+ PGTVVD KICHP  +DFY+C+HAG+ G
Sbjct: 827 PVTFIVVQKRHHTRLFANNHRDKNSTDRSGNILPGTVVDTKICHPTEFDFYLCSHAGIQG 886

Query: 836 TSRPTHYHVLLDEIGFSPDDLQELVHSLSYVYQRSTTAISVVAPICYAHLAASQVGQFMK 895
           TSRP HYHVL DE  F+ D +Q L ++L Y Y R T ++S+V P  YAHLAA +     +
Sbjct: 887 TSRPAHYHVLWDENNFTADGIQSLTNNLCYTYARCTRSVSIVPPAYYAHLAAFRA----R 942

Query: 896 FEDKSETSSSHGGSGR---------DINASPIPQLPKLMDSVCNSMFF 934
           F  + E    +G  G+         D+   P   LP L ++V   MF+
Sbjct: 943 FYLEPEIMQDNGSPGKKNTKTTTVGDVGVKP---LPALKENVKRVMFY 987


>AGO1_ARATH (O04379) Argonaute protein
          Length = 1048

 Score =  464 bits (1193), Expect = e-130
 Identities = 319/954 (33%), Positives = 482/954 (50%), Gaps = 108/954 (11%)

Query: 39   PPPPIVPADIEPIKIE---PQIVKKKLPT-----KVPMARRGLGSKGAKLPLLTNHFKVN 90
            P P ++    E + +E   P    + +P+     K PM R G G  G +  +  NHF   
Sbjct: 144  PEPTVLAQQFEQLSVEQGAPSQAIQPIPSSSKAFKFPM-RPGKGQSGKRCIVKANHFFAE 202

Query: 91   VTNTDGYFFQYSVALFYEDGRPVEGKGAGRKILDRVQETY-GSELNGKDLAYDGEKTLFT 149
            + + D     Y V +  E    V  +G  R ++ ++ + Y  S L  +  AYDG K+L+T
Sbjct: 203  LPDKD--LHHYDVTITPE----VTSRGVNRAVMKQLVDNYRDSHLGSRLPAYDGRKSLYT 256

Query: 150  IGSLAQNKLEFTVVLEDVTSNRNNGNASPDGHGSPNDTDRKRLKKSHRSKTYKVEISFAS 209
             G L  N  EF + L D             G G              R + +KV I   +
Sbjct: 257  AGPLPFNSKEFRINLLD----------EEVGAGG-----------QRREREFKVVIKLVA 295

Query: 210  KIPLQAIANALKGHETENYQEAIRVLDIILRQHAAKQGCLLVRQNFFHNDPKNFTDVGGG 269
            +  L  +   L+G +++  QEA++VLDI+LR+    +  + V ++F+  D      +G G
Sbjct: 296  RADLHHLGMFLEGKQSDAPQEALQVLDIVLRELPTSR-YIPVGRSFYSPDIGKKQSLGDG 354

Query: 270  VLGCRGLHSSFRTTQSGLSLNIDVSTTMIVHPGPVVDFL--IANQNVRD-PFS-LDWNKA 325
            +   RG + S R TQ GLSLNID+S+T  +   PV+ F+  + N+++   P S  D  K 
Sbjct: 355  LESWRGFYQSIRPTQMGLSLNIDMSSTAFIEANPVIQFVCDLLNRDISSRPLSDADRVKI 414

Query: 326  KRTLKNLRITTSPTN---QEYKITGLSEMPCKDQLFTLKKRGAVPGEDDTEEITVYDYFV 382
            K+ L+ +++  +      ++Y+I+GL+ +  ++  F + +R          + +V +YF 
Sbjct: 415  KKALRGVKVEVTHRGNMRRKYRISGLTAVATRELTFPVDERNT--------QKSVVEYFH 466

Query: 383  NRRKISLQYSADLPCINVGKPKRPTFVPVELCSLVSLQRYTKALSTLQRSSLVEKSRQKP 442
                  +Q++  LPC+ VG   RP ++P+E+C +V  QRY+K L+  Q ++L++ + Q+P
Sbjct: 467  ETYGFRIQHT-QLPCLQVGNSNRPNYLPMEVCKIVEGQRYSKRLNERQITALLKVTCQRP 525

Query: 443  QERMRVLTDALKTSDYGSEPMLRNCGISITSGFTQVDGRVLQAPRLKF---GNGEDFNPR 499
             +R + +   ++ +DY  +   +  GI I++    V+ R+L  P LK+   G      P+
Sbjct: 526  IDREKDILQTVQLNDYAKDNYAQEFGIKISTSLASVEARILPPPWLKYHESGREGTCLPQ 585

Query: 500  NGRWNFNNKKIVQPVKIEKWAVVNFSARCDVRGLVRDLIKCGGMKGIHVEQPFDCFEENG 559
             G+WN  NKK++    +  W  +NFS +     L R   +         E    C+    
Sbjct: 586  VGQWNMMNKKMINGGTVNNWICINFSRQVQ-DNLARTFCQ---------ELAQMCYVSGM 635

Query: 560  QFRRAPPLVRVEKMFEHVQSKLP------------GAPKFLLCLLSERKNSDLYGPWKKK 607
             F   P L  V    E V+  L             G    LL ++    N  LYG  K+ 
Sbjct: 636  AFNPEPVLPPVSARPEQVEKVLKTRYHDATSKLSQGKEIDLLIVILPDNNGSLYGDLKRI 695

Query: 608  NLAEFGIVTQCIAPTRV---NDQYLTNVLLKINAKLGGMNSLLGVEHSPSIPIVSKAPTL 664
               E GIV+QC     V   + QY+ NV LKIN K+GG N++L    S  IP+VS  PT+
Sbjct: 696  CETELGIVSQCCLTKHVFKMSKQYMANVALKINVKVGGRNTVLVDALSRRIPLVSDRPTI 755

Query: 665  ILGMDVSHGSPGQTEIPSIAAVVSSRQWPLISKYRACVRTQGAKVEMIDNLFKPVSDTED 724
            I G DV+H  PG+   PSIAAVV+S+ WP I+KY   V  Q  + E+I +LFK   D + 
Sbjct: 756  IFGADVTHPHPGEDSSPSIAAVVASQDWPEITKYAGLVCAQAHRQELIQDLFKEWKDPQK 815

Query: 725  E----GIIRELLIDFYNSSGNRKPDNIIIFRDGVSESQFNQVLNIELSQIIEACKFLDEK 780
                 G+I+ELLI F  S+G+ KP  II +RDGVSE QF QVL  EL  I +AC  L+  
Sbjct: 816  GVVTGGMIKELLIAFRRSTGH-KPLRIIFYRDGVSEGQFYQVLLYELDAIRKACASLEAG 874

Query: 781  WNPKFLVIVAQKNHHTKFFQPGSPD--------NVPPGTVVDNKICHPRNYDFYMCAHAG 832
            + P    +V QK HHT+ F     D        N+ PGTVVD+KICHP  +DFY+C+HAG
Sbjct: 875  YQPPVTFVVVQKRHHTRLFAQNHNDRHSVDRSGNILPGTVVDSKICHPTEFDFYLCSHAG 934

Query: 833  MIGTSRPTHYHVLLDEIGFSPDDLQELVHSLSYVYQRSTTAISVVAPICYAHLAASQVGQ 892
            + GTSRP HYHVL DE  F+ D LQ L ++L Y Y R T ++S+V P  YAHLAA +   
Sbjct: 935  IQGTSRPAHYHVLWDENNFTADGLQSLTNNLCYTYARCTRSVSIVPPAYYAHLAAFRARF 994

Query: 893  FMKFEDKSETSSSHGGSGR------------DINASPIPQLPKLMDSVCNSMFF 934
            +M+ E     S + G   R            ++NA+  P LP L ++V   MF+
Sbjct: 995  YMEPETSDSGSMASGSMARGGGMAGRSTRGPNVNAAVRP-LPALKENVKRVMFY 1047


>I2C2_RAT (Q9QZ81) Eukaryotic translation initiation factor 2C 2
           (eIF2C 2) (eIF-2C 2) (Golgi ER protein 95 kDa) (GERp95)
          Length = 860

 Score =  380 bits (977), Expect = e-105
 Identities = 278/884 (31%), Positives = 442/884 (49%), Gaps = 102/884 (11%)

Query: 67  PMARRGLGSKGAKLPLLTNHFKVNVTNTDGYFFQYSVALFYEDGRPVE-GKGAGRKILDR 125
           P  R   G+ G  + L  N F++++   D Y ++  +       +P +  +   R+I++ 
Sbjct: 26  PPPRPDFGTTGRTIKLQANFFEMDIPKIDIYHYELDI-------KPEKCPRRVNREIVEH 78

Query: 126 VQETYGSELNG-KDLAYDGEKTLFTIGSL--AQNKLEFTVVLEDVTSNRNNGNASPDGHG 182
           + + + +++ G +   +DG K L+T   L   ++K+E  V L               G G
Sbjct: 79  MVQHFKTQIFGDRKPVFDGRKNLYTAMPLPIGRDKVELEVTLP--------------GEG 124

Query: 183 SPNDTDRKRLKKSHRSKTYKVEISFASKIPLQAIANALKGHETENYQEAIRVLDIILRQH 242
                         + + +KV I + S + LQA+ +AL G       E I+ LD+++R H
Sbjct: 125 --------------KDRIFKVSIKWVSCVSLQALHDALSGRLPSVPFETIQALDVVMR-H 169

Query: 243 AAKQGCLLVRQNFFHNDPKNFTDVGGGVLGCRGLHSSFRTTQSGLSLNIDVSTTMIVHPG 302
                   V ++FF         +GGG     G H S R +   + LNIDVS T      
Sbjct: 170 LPSMRYTPVGRSFFTASEGCSNPLGGGREVWFGFHQSVRPSLWKMMLNIDVSATAFYKAQ 229

Query: 303 PVVDFLI------ANQNVRDPFSLDWNKAKRT--LKNLRITTSPTNQ---EYKITGLSEM 351
           PV++F+       + +  + P + D  + K T  +K L++  +   Q   +Y++  ++  
Sbjct: 230 PVIEFVCEVLDFKSIEEQQKPLT-DSQRVKFTKEIKGLKVEITHCGQMKRKYRVCNVTRR 288

Query: 352 PCKDQLFTLKKRGAVPGEDDTEEITVYDYFVNRRKISLQYSADLPCINVGKPKRPTFVPV 411
           P   Q F L++         T E TV  YF +R K+ L+Y   LPC+ VG+ ++ T++P+
Sbjct: 289 PASHQTFPLQQESG-----QTVECTVAQYFKDRHKLVLRYP-HLPCLQVGQEQKHTYLPL 342

Query: 412 ELCSLVSLQRYTKALSTLQRSSLVEKSRQKPQERMRVLTDALKTSDYGSEPMLRNCGISI 471
           E+C++V+ QR  K L+  Q S+++  + +   +R   ++  ++++ + ++P +R  GI +
Sbjct: 343 EVCNIVAGQRCIKKLTDNQTSTMIRATARSAPDRQEEISKLMRSASFNTDPYVREFGIMV 402

Query: 472 TSGFTQVDGRVLQAPRLKFG--NGEDFNPRNGRWNFNNKKIVQPVKIEKWAVVNFSAR-- 527
               T V GRVLQ P + +G  N     P  G W+  NK+    ++I+ WA+  F+ +  
Sbjct: 403 KDEMTDVTGRVLQPPSILYGGRNKAIATPVQGVWDMRNKQFHTGIEIKVWAIACFAPQRQ 462

Query: 528 ---CDVRGLVRDLIKCGGMKGIHVE-QPFDCFEENGQFRRAPPLVRVEKMFEHVQSKLPG 583
                ++     L K     G+ ++ QP  C       + A     VE MF H+++   G
Sbjct: 463 CTEVHLKSFTEQLRKISRDAGMPIQGQPCFC-------KYAQGADSVEPMFRHLKNTYAG 515

Query: 584 APKFLLCLLSERKNSDLYGPWKKKNLAEFGIVTQCIAPT---RVNDQYLTNVLLKINAKL 640
               ++ L  +   + +Y   K+      G+ TQC+      R   Q L+N+ LKIN KL
Sbjct: 516 LQLVVVILPGK---TPVYAEVKRVGDTVLGMATQCVQMKNVQRTTPQTLSNLCLKINVKL 572

Query: 641 GGMNSLLGVEHSPSIPIVSKAPTLILGMDVSHGSPGQTEIPSIAAVVSSRQWPLISKYRA 700
           GG+N++L  +  P    V + P + LG DV+H   G  + PSIAAVV S      ++Y A
Sbjct: 573 GGVNNILLPQGRPP---VFQQPVIFLGADVTHPPAGDGKKPSIAAVVGSMD-AHPNRYCA 628

Query: 701 CVRTQGAKVEMIDNLFKPVSDTEDEGIIRELLIDFYNSSGNRKPDNIIIFRDGVSESQFN 760
            VR Q  + E+I +L           ++RELLI FY S+   KP  II +RDGVSE QF 
Sbjct: 629 TVRVQQHRQEIIQDL---------AAMVRELLIQFYKST-RFKPTRIIFYRDGVSEGQFQ 678

Query: 761 QVLNIELSQIIEACKFLDEKWNPKFLVIVAQKNHHTKFF------QPGSPDNVPPGTVVD 814
           QVL+ EL  I EAC  L++++ P    IV QK HHT+ F      + G   N+P GT VD
Sbjct: 679 QVLHHELLAIREACIKLEKEYQPGITFIVVQKRHHTRLFCTDKNERVGKSGNIPAGTTVD 738

Query: 815 NKICHPRNYDFYMCAHAGMIGTSRPTHYHVLLDEIGFSPDDLQELVHSLSYVYQRSTTAI 874
            KI HP  +DFY+C+HAG+ GTSRP+HYHVL D+  FS D+LQ L + L + Y R T ++
Sbjct: 739 TKITHPTEFDFYLCSHAGIQGTSRPSHYHVLWDDNRFSSDELQILTYQLCHTYVRCTRSV 798

Query: 875 SVVAPICYAHLAASQVGQFM--KFEDKSETSSSHGGS-GRDINA 915
           S+ AP  YAHL A +    +  K  D +E S + G S GRD  A
Sbjct: 799 SIPAPAYYAHLVAFRARYHLVDKEHDSAEGSHTSGQSNGRDHQA 842


>I2C2_MOUSE (Q8CJG0) Eukaryotic translation initiation factor 2C 2
           (eIF2C 2) (eIF-2C 2) (Piwi/argonaute family protain
           meIF2C2)
          Length = 860

 Score =  379 bits (972), Expect = e-104
 Identities = 278/883 (31%), Positives = 439/883 (49%), Gaps = 100/883 (11%)

Query: 67  PMARRGLGSKGAKLPLLTNHFKVNVTNTDGYFFQYSVALFYEDGRPVEGKGAGRKILDRV 126
           P  R   G+ G  + L  N F++++   D Y ++  +     + RP   +   R+I++ +
Sbjct: 26  PPPRPDFGTTGRTIKLQANFFEMDIPKIDIYHYELDIK---PEKRP---RRVNREIVEHM 79

Query: 127 QETYGSELNG-KDLAYDGEKTLFTIGSL--AQNKLEFTVVLEDVTSNRNNGNASPDGHGS 183
            + + +++ G +   +DG K L+T   L   ++K+E  V L               G G 
Sbjct: 80  VQHFKTQIFGDRKPVFDGRKNLYTAMPLPIGRDKVELEVTLP--------------GEG- 124

Query: 184 PNDTDRKRLKKSHRSKTYKVEISFASKIPLQAIANALKGHETENYQEAIRVLDIILRQHA 243
                        + +  KV I + S + LQA+ +AL G       E I+ LD+++R H 
Sbjct: 125 -------------KDRILKVSIKWVSCVSLQALHDALSGRLPSVPFETIQALDVVMR-HL 170

Query: 244 AKQGCLLVRQNFFHNDPKNFTDVGGGVLGCRGLHSSFRTTQSGLSLNIDVSTTMIVHPGP 303
                  V ++FF         +GGG     G H S R +   + LNIDVS T      P
Sbjct: 171 PSMRYTPVGRSFFTASEGCSNPLGGGREVWFGFHQSVRPSLWKMMLNIDVSATAFYKAQP 230

Query: 304 VVDFLI------ANQNVRDPFSLDWNKAKRT--LKNLRITTSPTNQ---EYKITGLSEMP 352
           V++F+       + +  + P + D  + K T  +K L++  +   Q   +Y++  ++  P
Sbjct: 231 VIEFVCEVLDFKSIEEQQKPLT-DSQRVKFTKEIKGLKVEITHCGQMKRKYRVCNVTRRP 289

Query: 353 CKDQLFTLKKRGAVPGEDDTEEITVYDYFVNRRKISLQYSADLPCINVGKPKRPTFVPVE 412
              Q F L++         T E TV  YF +R K+ L+Y   LPC+ VG+ ++ T++P+E
Sbjct: 290 ASHQTFPLQQESG-----QTVECTVAQYFKDRHKLVLRYP-HLPCLQVGQEQKHTYLPLE 343

Query: 413 LCSLVSLQRYTKALSTLQRSSLVEKSRQKPQERMRVLTDALKTSDYGSEPMLRNCGISIT 472
           +C++V+ QR  K L+  Q S+++  + +   +R   ++  ++++ + ++P +R  GI + 
Sbjct: 344 VCNIVAGQRCIKKLTDDQTSTMIRATARSAPDRQEEISKLMRSASFNTDPYVREFGIMVK 403

Query: 473 SGFTQVDGRVLQAPRLKFG--NGEDFNPRNGRWNFNNKKIVQPVKIEKWAVVNFSAR--- 527
              T V GRVLQ P + +G  N     P  G W+  NK+    ++I+ WA+  F+ +   
Sbjct: 404 DEMTDVTGRVLQPPSILYGGRNKAIATPVQGVWDMRNKQFHTGIEIKVWAIACFAPQRQC 463

Query: 528 --CDVRGLVRDLIKCGGMKGIHVE-QPFDCFEENGQFRRAPPLVRVEKMFEHVQSKLPGA 584
               ++     L K     G+ ++ QP  C       + A     VE MF H+++   G 
Sbjct: 464 TEVHLKSFTEQLRKISRDAGMPIQGQPCFC-------KYAQGADSVEPMFRHLKNTYAGL 516

Query: 585 PKFLLCLLSERKNSDLYGPWKKKNLAEFGIVTQCIAPT---RVNDQYLTNVLLKINAKLG 641
              ++ L  +   + +Y   K+      G+ TQC+      R   Q L+N+ LKIN KLG
Sbjct: 517 QLVVVILPGK---TPVYAEVKRVGDTVLGMATQCVQMKNVQRTTPQTLSNLCLKINVKLG 573

Query: 642 GMNSLLGVEHSPSIPIVSKAPTLILGMDVSHGSPGQTEIPSIAAVVSSRQWPLISKYRAC 701
           G+N++L  +  P    V + P + LG DV+H   G  + PSIAAVV S      ++Y A 
Sbjct: 574 GVNNILLPQGRPP---VFQQPVIFLGADVTHPPAGDGKKPSIAAVVGSMD-AHPNRYCAT 629

Query: 702 VRTQGAKVEMIDNLFKPVSDTEDEGIIRELLIDFYNSSGNRKPDNIIIFRDGVSESQFNQ 761
           VR Q  + E+I +L           ++RELLI FY S+   KP  II +RDGVSE QF Q
Sbjct: 630 VRVQQHRQEIIQDL---------AAMVRELLIQFYKST-RFKPTRIIFYRDGVSEGQFQQ 679

Query: 762 VLNIELSQIIEACKFLDEKWNPKFLVIVAQKNHHTKFF------QPGSPDNVPPGTVVDN 815
           VL+ EL  I EAC  L++ + P    IV QK HHT+ F      + G   N+P GT VD 
Sbjct: 680 VLHHELLAIREACIKLEKDYQPGITFIVVQKRHHTRLFCTDKNERVGKSGNIPAGTTVDT 739

Query: 816 KICHPRNYDFYMCAHAGMIGTSRPTHYHVLLDEIGFSPDDLQELVHSLSYVYQRSTTAIS 875
           KI HP  +DFY+C+HAG+ GT RP+HYHVL D+  FS D+LQ L + L + Y R T ++S
Sbjct: 740 KITHPTEFDFYLCSHAGIQGTGRPSHYHVLWDDNRFSSDELQILTYQLCHTYVRCTRSVS 799

Query: 876 VVAPICYAHLAASQVGQFM--KFEDKSETSSSHGGS-GRDINA 915
           + AP  YAHL A +    +  K  D +E S + G S GRD  A
Sbjct: 800 IPAPAYYAHLVAFRARYHLVDKEHDSAEGSHTSGQSNGRDHQA 842


>I2C2_RABIT (O77503) Eukaryotic translation initiation factor 2C 2
           (eIF2C 2) (eIF-2C 2) (Fragment)
          Length = 840

 Score =  378 bits (970), Expect = e-104
 Identities = 277/884 (31%), Positives = 438/884 (49%), Gaps = 102/884 (11%)

Query: 67  PMARRGLGSKGAKLPLLTNHFKVNVTNTDGYFFQYSVALFYEDGRPVE-GKGAGRKILDR 125
           P  R   G+ G  + L  N F++++   D Y ++  +       +P +  +   R+I++ 
Sbjct: 6   PPPRPDFGTSGRTIKLQANFFEMDIPKIDIYHYELDI-------KPEKCPRRVNREIVEH 58

Query: 126 VQETYGSELNG-KDLAYDGEKTLFTIGSL--AQNKLEFTVVLEDVTSNRNNGNASPDGHG 182
           + + + +++ G +   +DG K L+T   L   + K+E  V L               G G
Sbjct: 59  MVQHFKAQIFGDRKPVFDGRKNLYTAMPLPIGREKVELEVTLP--------------GEG 104

Query: 183 SPNDTDRKRLKKSHRSKTYKVEISFASKIPLQAIANALKGHETENYQEAIRVLDIILRQH 242
                         + + +KV I + S + LQA+ +AL G       E I+ LD+++R H
Sbjct: 105 --------------KDRIFKVSIKWVSCVSLQALHDALSGRLPSVPFETIQALDVVMR-H 149

Query: 243 AAKQGCLLVRQNFFHNDPKNFTDVGGGVLGCRGLHSSFRTTQSGLSLNIDVSTTMIVHPG 302
                   V ++FF         +GGG     G H S R +   + LNIDVS T      
Sbjct: 150 LPSMRYTPVGRSFFTASEGCSNPLGGGREVWFGFHQSVRPSLWKMMLNIDVSATAFYKAQ 209

Query: 303 PVVDFLI------ANQNVRDPFSLDWNKAKRT--LKNLRITTSPTNQ---EYKITGLSEM 351
           PV++F+       + +  + P + D  + K T  +K L++  +   Q   +Y++  ++  
Sbjct: 210 PVIEFVCEVLDFKSIEEQQKPLT-DSQRVKFTKEIKGLKVEITHCGQMKRKYRVCNVTRR 268

Query: 352 PCKDQLFTLKKRGAVPGEDDTEEITVYDYFVNRRKISLQYSADLPCINVGKPKRPTFVPV 411
           P   Q F L++         T E TV  YF +R K+ L+Y   LPC+ VG+ ++ T++P+
Sbjct: 269 PASHQTFPLQQESG-----QTVECTVAQYFKDRHKLVLRYP-HLPCLQVGQEQKHTYLPL 322

Query: 412 ELCSLVSLQRYTKALSTLQRSSLVEKSRQKPQERMRVLTDALKTSDYGSEPMLRNCGISI 471
           E+C++V+ QR  K L+  Q S+++  + +   +R   ++  ++++ + ++P +R  GI +
Sbjct: 323 EVCNIVAGQRCIKKLTDNQTSTMIRATARSAPDRQEEISKLMRSASFNTDPYVREFGIMV 382

Query: 472 TSGFTQVDGRVLQAPRLKFG--NGEDFNPRNGRWNFNNKKIVQPVKIEKWAVVNFSAR-- 527
               T V GRVLQ P + +G  N     P  G W+  NK+    ++I+ WA+  F+ +  
Sbjct: 383 KDEMTDVTGRVLQPPSILYGGRNKAIATPVQGVWDMRNKQFHTGIEIKVWAIACFAPQRQ 442

Query: 528 ---CDVRGLVRDLIKCGGMKGIHVE-QPFDCFEENGQFRRAPPLVRVEKMFEHVQSKLPG 583
                ++     L K     G+ ++ QP  C    G     P       MF H+++   G
Sbjct: 443 CTEVHLKSFTEQLRKISRDAGMPIQGQPCFCKYAQGADSVGP-------MFRHLKNTYAG 495

Query: 584 APKFLLCLLSERKNSDLYGPWKKKNLAEFGIVTQCIAPT---RVNDQYLTNVLLKINAKL 640
               ++ L  +   + +Y   K+      G+ TQC+      R   Q L+N+ LKIN KL
Sbjct: 496 LQLVVVILPGK---TPVYAEVKRVGDTVLGMATQCVQMKNVQRTTPQTLSNLCLKINVKL 552

Query: 641 GGMNSLLGVEHSPSIPIVSKAPTLILGMDVSHGSPGQTEIPSIAAVVSSRQWPLISKYRA 700
           GG+N++L  +  P    V + P + LG DV+H   G  + PSIAAVV S      ++Y A
Sbjct: 553 GGVNNILLPQGRPP---VFQQPVIFLGADVTHPPAGDGKKPSIAAVVGSMD-AHPNRYCA 608

Query: 701 CVRTQGAKVEMIDNLFKPVSDTEDEGIIRELLIDFYNSSGNRKPDNIIIFRDGVSESQFN 760
            VR Q  + E+I +L           ++RELLI FY S+   KP  II +RDGVSE QF 
Sbjct: 609 TVRVQQHRQEIIQDL---------AAMVRELLIQFYKST-RFKPTRIIFYRDGVSEGQFQ 658

Query: 761 QVLNIELSQIIEACKFLDEKWNPKFLVIVAQKNHHTKFF------QPGSPDNVPPGTVVD 814
           QVL+ EL  I EAC  L++ + P    IV QK HHT+ F      + G   N+P GT VD
Sbjct: 659 QVLHHELLAIREACIKLEKDYQPGITFIVVQKRHHTRLFCTDKNERVGKSGNIPAGTTVD 718

Query: 815 NKICHPRNYDFYMCAHAGMIGTSRPTHYHVLLDEIGFSPDDLQELVHSLSYVYQRSTTAI 874
            KI HP  +DFY+C+HAG+ GTSRP+HYHVL D+  FS D+LQ L + L + Y R T ++
Sbjct: 719 TKITHPTEFDFYLCSHAGIQGTSRPSHYHVLWDDNRFSSDELQILTYQLCHTYVRCTRSV 778

Query: 875 SVVAPICYAHLAASQVGQFM--KFEDKSETSSSHGGS-GRDINA 915
           S+ AP  YAHL A +    +  K  D +E S + G S GRD  A
Sbjct: 779 SIPAPAYYAHLVAFRARYHLVDKEHDSAEGSHTSGQSNGRDHQA 822


>I2C4_HUMAN (Q9HCK5) Eukaryotic translation initiation factor 2C 4
           (eIF2C 4) (eIF-2C 4) (Argonaute 4)
          Length = 861

 Score =  376 bits (965), Expect = e-103
 Identities = 275/885 (31%), Positives = 433/885 (48%), Gaps = 92/885 (10%)

Query: 67  PMARRGLGSKGAKLPLLTNHFKVNVTNTDGYFFQYSVALFYEDGRPVEGKGAGRKILDRV 126
           P  R GLG+ G  + LL NHF+V +   D Y +   +     + RP   +   R+++D +
Sbjct: 15  PPRRPGLGTVGKPIRLLANHFQVQIPKIDVYHYDVDIK---PEKRP---RRVNREVVDTM 68

Query: 127 QETYGSELNG-KDLAYDGEKTLFTIGSL--AQNKLEFTVVLEDVTSNRNNGNASPDGHGS 183
              +  ++ G +   YDG++ ++T   L   +++++  V L               G G 
Sbjct: 69  VRHFKMQIFGDRQPGYDGKRNMYTAHPLPIGRDRVDMEVTLP--------------GEG- 113

Query: 184 PNDTDRKRLKKSHRSKTYKVEISFASKIPLQAIANALKGHETENYQEAIRVLDIILRQHA 243
                        + +T+KV + + S + LQ +  AL GH  E   ++++ LD+I R H 
Sbjct: 114 -------------KDQTFKVSVQWVSVVSLQLLLEALAGHLNEVPDDSVQALDVITR-HL 159

Query: 244 AKQGCLLVRQNFFHNDPKNFTDVGGGVLGCRGLHSSFRTTQSGLSLNIDVSTTMIVHPGP 303
                  V ++FF      +  +GGG     G H S R     + LNIDVS T      P
Sbjct: 160 PSMRYTPVGRSFFSPPEGYYHPLGGGREVWFGFHQSVRPAMWNMMLNIDVSATAFYRAQP 219

Query: 304 VVDFL-----IANQNVRDPFSLDWNKAKRT--LKNLRITTSPTNQ---EYKITGLSEMPC 353
           +++F+     I N N +     D  + K T  ++ L++  +   Q   +Y++  ++  P 
Sbjct: 220 IIEFMCEVLDIQNINEQTKPLTDSQRVKFTKEIRGLKVEVTHCGQMKRKYRVCNVTRRPA 279

Query: 354 KDQLFTLKKRGAVPGEDDTEEITVYDYFVNRRKISLQYSADLPCINVGKPKRPTFVPVEL 413
             Q F L+            E TV  YF  +  + L+Y   LPC+ VG+ ++ T++P+E+
Sbjct: 280 SHQTFPLQLENG-----QAMECTVAQYFKQKYSLQLKYP-HLPCLQVGQEQKHTYLPLEV 333

Query: 414 CSLVSLQRYTKALSTLQRSSLVEKSRQKPQERMRVLTDALKTSDY--GSEPMLRNCGISI 471
           C++V+ QR  K L+  Q S++++ + +   +R   ++  +K++    G +P L+  GI +
Sbjct: 334 CNIVAGQRCIKKLTDNQTSTMIKATARSAPDRQEEISRLVKSNSMVGGPDPYLKEFGIVV 393

Query: 472 TSGFTQVDGRVLQAPRLKFG--NGEDFNPRNGRWNFNNKKIVQPVKIEKWAVVNFSARCD 529
            +  T++ GRVL AP L++G  N     P  G W+   K+    ++I+ WAV  F+ +  
Sbjct: 394 HNEMTELTGRVLPAPMLQYGGRNKTVATPNQGVWDMRGKQFYAGIEIKVWAVACFAPQKQ 453

Query: 530 VR-----GLVRDLIKCGGMKGIHVE-QPFDCFEENGQFRRAPPLVRVEKMFEHVQSKLPG 583
            R          L K     G+ ++ QP  C       + A     VE MF+H++    G
Sbjct: 454 CREDLLKSFTDQLRKISKDAGMPIQGQPCFC-------KYAQGADSVEPMFKHLKMTYVG 506

Query: 584 APKFLLCLLSERKNSDLYGPWKKKNLAEFGIVTQCIAPTRV---NDQYLTNVLLKINAKL 640
               ++ L  +   + +Y   K+      G+ TQC+    V   + Q L+N+ LKINAKL
Sbjct: 507 LQLIVVILPGK---TPVYAEVKRVGDTLLGMATQCVQVKNVVKTSPQTLSNLCLKINAKL 563

Query: 641 GGMNSLLGVEHSPSIPIVSKAPTLILGMDVSHGSPGQTEIPSIAAVVSSRQWPLISKYRA 700
           GG+N++L     PS   V + P + LG DV+H   G  + PSIAAVV S      S+Y A
Sbjct: 564 GGINNVLVPHQRPS---VFQQPVIFLGADVTHPPAGDGKKPSIAAVVGSMDGHP-SRYCA 619

Query: 701 CVRTQGAKVEMIDNLFKPVSDTED-EGIIRELLIDFYNSSGNRKPDNIIIFRDGVSESQF 759
            VR Q ++ E+   L       +D   ++RELLI FY S+   KP  II +R GVSE Q 
Sbjct: 620 TVRVQTSRQEISQELLYSQEVIQDLTNMVRELLIQFYKST-RFKPTRIIYYRGGVSEGQM 678

Query: 760 NQVLNIELSQIIEACKFLDEKWNPKFLVIVAQKNHHTKFF------QPGSPDNVPPGTVV 813
            QV   EL  I +AC  L+E + P    IV QK HHT+ F      + G   NVP GT V
Sbjct: 679 KQVAWPELIAIRKACISLEEDYRPGITYIVVQKRHHTRLFCADKTERVGKSGNVPAGTTV 738

Query: 814 DNKICHPRNYDFYMCAHAGMIGTSRPTHYHVLLDEIGFSPDDLQELVHSLSYVYQRSTTA 873
           D+ I HP  +DFY+C+HAG+ GTSRP+HY VL D+  F+ D+LQ L + L + Y R T +
Sbjct: 739 DSTITHPSEFDFYLCSHAGIQGTSRPSHYQVLWDDNCFTADELQLLTYQLCHTYVRCTRS 798

Query: 874 ISVVAPICYAHLAASQVGQFMKFEDKSETSSSH---GGSGRDINA 915
           +S+ AP  YA L A +    +  +D      SH     +GRD  A
Sbjct: 799 VSIPAPAYYARLVAFRARYHLVDKDHDSAEGSHVSGQSNGRDPQA 843


>I2C2_HUMAN (Q9UKV8) Eukaryotic translation initiation factor 2C 2
           (eIF2C 2) (eIF-2C 2)
          Length = 851

 Score =  370 bits (950), Expect = e-102
 Identities = 268/830 (32%), Positives = 419/830 (50%), Gaps = 94/830 (11%)

Query: 120 RKILDRVQETYGSELNG-KDLAYDGEKTLFTIGSL--AQNKLEFTVVLEDVTSNRNNGNA 176
           R+I++ + + + +++ G +   +DG K L+T   L   ++K+E  V L            
Sbjct: 64  REIVEHMVQHFKTQIFGDRKPVFDGRKNLYTAMPLPIGRDKVELEVTLP----------- 112

Query: 177 SPDGHGSPNDTDRKRLKKSHRSKTYKVEISFASKIPLQAIANALKGHETENYQEAIRVLD 236
              G G              + + +KV I + S + LQA+ +AL G       E I+ LD
Sbjct: 113 ---GEG--------------KDRIFKVSIKWVSCVSLQALHDALSGRLPSVPFETIQALD 155

Query: 237 IILRQHAAKQGCLLVRQNFFHNDPKNFTDVGGGVLGCRGLHSSFRTTQSGLSLNIDVSTT 296
           +++R H        V ++FF         +GGG     G H S R +   + LNIDVS T
Sbjct: 156 VVMR-HLPSMRYTPVGRSFFTASEGCSNPLGGGREVWFGFHQSVRPSLWKMMLNIDVSAT 214

Query: 297 MIVHPGPVVDFLI------ANQNVRDPFSLDWNKAKRT--LKNLRITTSPTNQ---EYKI 345
                 PV++F+       + +  + P + D  + K T  +K L++  +   Q   +Y++
Sbjct: 215 AFYKAQPVIEFVCEVLDFKSIEEQQKPLT-DSQRVKFTKEIKGLKVEITHCGQMKRKYRV 273

Query: 346 TGLSEMPCKDQLFTLKKRGAVPGEDDTEEITVYDYFVNRRKISLQYSADLPCINVGKPKR 405
             ++  P   Q F L++         T E TV  YF +R K+ L+Y   LPC+ VG+ ++
Sbjct: 274 CNVTRRPASHQTFPLQQESG-----QTVECTVAQYFKDRHKLVLRYP-HLPCLQVGQEQK 327

Query: 406 PTFVPVELCSLVSLQRYTKALSTLQRSSLVEKSRQKPQERMRVLTDALKTSDYGSEPMLR 465
            T++P+E+C++V+ QR  K L+  Q S+++  + +   +R   ++  ++++ + ++P +R
Sbjct: 328 HTYLPLEVCNIVAGQRCIKKLTDNQTSTMIRATARSAPDRQEEISKLMRSASFNTDPYVR 387

Query: 466 NCGISITSGFTQVDGRVLQAPRLKFG--NGEDFNPRNGRWNFNNKKIVQPVKIEKWAVVN 523
             GI +    T V GRVLQ P + +G  N     P  G W+  NK+    ++I+ WA+  
Sbjct: 388 EFGIMVKDEMTDVTGRVLQPPSILYGGRNKAIATPVQGVWDMRNKQFHTGIEIKVWAIAC 447

Query: 524 FSAR-----CDVRGLVRDLIKCGGMKGIHVE-QPFDCFEENGQFRRAPPLVRVEKMFEHV 577
           F+ +       ++     L K     G+ ++ QP  C       + A     VE MF H+
Sbjct: 448 FAPQRQCTEVHLKSFTEQLRKISRDAGMPIQGQPCFC-------KYAQGADSVEPMFRHL 500

Query: 578 QSKLPGAPKFLLCLLSERKNSDLYGPWKKKNLAEFGIVTQCIAPT---RVNDQYLTNVLL 634
           ++   G    ++ L  +   + +Y   K+      G+ TQC+      R   Q L+N+ L
Sbjct: 501 KNTYAGLQLVVVILPGK---TPVYAEVKRVGDTVLGMATQCVQMKNVQRTTPQTLSNLCL 557

Query: 635 KINAKLGGMNSLLGVEHSPSIPIVSKAPTLILGMDVSHGSPGQTEIPSIAAVVSSRQWPL 694
           KIN KLGG+N++L  +  P    V + P + LG DV+H   G  + PSIAAVV S     
Sbjct: 558 KINVKLGGVNNILLPQGRPP---VFQQPVIFLGADVTHPPAGDGKKPSIAAVVGSMD-AH 613

Query: 695 ISKYRACVRTQGAKVEMIDNLFKPVSDTEDEGIIRELLIDFYNSSGNRKPDNIIIFRDGV 754
            ++Y A VR Q  + E+I +L           ++RELLI FY S+   KP  II +RDGV
Sbjct: 614 PNRYCATVRVQQHRQEIIQDL---------AAMVRELLIQFYKST-RFKPTRIIFYRDGV 663

Query: 755 SESQFNQVLNIELSQIIEACKFLDEKWNPKFLVIVAQKNHHTKFF------QPGSPDNVP 808
           SE QF QVL+ EL  I EAC  L++ + P    IV QK HHT+ F      + G   N+P
Sbjct: 664 SEGQFQQVLHHELLAIREACIKLEKDYQPGITFIVVQKRHHTRLFCTDKNERVGKSGNIP 723

Query: 809 PGTVVDNKICHPRNYDFYMCAHAGMIGTSRPTHYHVLLDEIGFSPDDLQELVHSLSYVYQ 868
            GT VD KI HP  +DFY+C+HAG+ GTSRP+HYHVL D+  FS D+LQ L + L + Y 
Sbjct: 724 AGTTVDTKITHPTEFDFYLCSHAGIQGTSRPSHYHVLWDDNRFSSDELQILTYQLCHTYV 783

Query: 869 RSTTAISVVAPICYAHLAASQVGQFM--KFEDKSETSSSHGGS-GRDINA 915
           R T ++S+ AP  YAHL A +    +  K  D +E S + G S GRD  A
Sbjct: 784 RCTRSVSIPAPAYYAHLVAFRARYHLVDKEHDSAEGSHTSGQSNGRDHQA 833


>I2C1_HUMAN (Q9UL18) Eukaryotic translation initiation factor 2C 1
           (eIF2C 1) (eIF-2C 1) (Putative RNA-binding protein Q99)
          Length = 857

 Score =  365 bits (936), Expect = e-100
 Identities = 268/879 (30%), Positives = 433/879 (48%), Gaps = 98/879 (11%)

Query: 70  RRGLGSKGAKLPLLTNHFKVNVTNTDGYFFQYSVALFYEDGRPVEGKGAGRKILDRVQET 129
           R G+G+ G  + LL N+F+V++   D Y ++  +     D  P   +   R++++ + + 
Sbjct: 26  RPGIGTVGKPIKLLANYFEVDIPKIDVYHYEVDIK---PDKCP---RRVNREVVEYMVQH 79

Query: 130 YGSELNG-KDLAYDGEKTLFTIGSL--AQNKLEFTVVLEDVTSNRNNGNASPDGHGSPND 186
           +  ++ G +   YDG+K ++T+ +L     +++F V +               G G    
Sbjct: 80  FKPQIFGDRKPVYDGKKNIYTVTALPIGNERVDFEVTIP--------------GEG---- 121

Query: 187 TDRKRLKKSHRSKTYKVEISFASKIPLQAIANALKGHETENYQEAIRVLDIILRQHAAKQ 246
                     + + +KV I + + +  + +  AL   +     E+++ LD+ +R H A  
Sbjct: 122 ----------KDRIFKVSIKWLAIVSWRMLHEALVSGQIPVPLESVQALDVAMR-HLASM 170

Query: 247 GCLLVRQNFFHNDPKNFTDVGGGVLGCRGLHSSFRTTQSGLSLNIDVSTTMIVHPGPVVD 306
               V ++FF      +  +GGG     G H S R     + LNIDVS T      PV++
Sbjct: 171 RYTPVGRSFFSPPEGYYHPLGGGREVWFGFHQSVRPAMWKMMLNIDVSATAFYKAQPVIE 230

Query: 307 FL-----IANQNVRDPFSLDWNKAKRT--LKNLRITTSPTNQ---EYKITGLSEMPCKDQ 356
           F+     I N N +     D  + + T  +K L++  +   Q   +Y++  ++  P   Q
Sbjct: 231 FMCEVLDIRNINEQPKPLTDSQRVRFTKEIKGLKVEVTHCGQMKRKYRVCNVTRRPASHQ 290

Query: 357 LFTLKKRGAVPGEDDTEEITVYDYFVNRRKISLQYSADLPCINVGKPKRPTFVPVELCSL 416
            F L+          T E TV  YF  +  + L+Y   LPC+ VG+ ++ T++P+E+C++
Sbjct: 291 TFPLQLESG-----QTVECTVAQYFKQKYNLQLKYP-HLPCLQVGQEQKHTYLPLEVCNI 344

Query: 417 VSLQRYTKALSTLQRSSLVEKSRQKPQERMRVLTDALKTSDYGSEPMLRNCGISITSGFT 476
           V+ QR  K L+  Q S++++ + +   +R   ++  +K + Y  +P ++  GI +    T
Sbjct: 345 VAGQRCIKKLTDNQTSTMIKATARSAPDRQEEISRLMKNASYNLDPYIQEFGIKVKDDMT 404

Query: 477 QVDGRVLQAPRLKFG--NGEDFNPRNGRWNFNNKKIVQPVKIEKWAVVNFSARCDVR--- 531
           +V GRVL AP L++G  N     P  G W+   K+    ++I+ WA+  F+ +   R   
Sbjct: 405 EVTGRVLPAPILQYGGRNRAIATPNQGVWDMRGKQFYNGIEIKVWAIACFAPQKQCREEV 464

Query: 532 --GLVRDLIKCGGMKGIHVE-QPFDCFEENGQFRRAPPLVRVEKMFEHVQSKLPGAPKFL 588
                  L K     G+ ++ QP  C       + A     VE MF H+++   G    +
Sbjct: 465 LKNFTDQLRKISKDAGMPIQGQPCFC-------KYAQGADSVEPMFRHLKNTYSGLQLII 517

Query: 589 LCLLSERKNSDLYGPWKKKNLAEFGIVTQCIAPTRV---NDQYLTNVLLKINAKLGGMNS 645
           + L  +   + +Y   K+      G+ TQC+    V   + Q L+N+ LKIN KLGG+N+
Sbjct: 518 VILPGK---TPVYAEVKRVGDTLLGMATQCVQVKNVVKTSPQTLSNLCLKINVKLGGINN 574

Query: 646 LLGVEHSPSIPIVSKAPTLILGMDVSHGSPGQTEIPSIAAVVSSRQWPLISKYRACVRTQ 705
           +L V H  S   V + P + LG DV+H   G  + PSI AVV S      S+Y A VR Q
Sbjct: 575 IL-VPHQRSA--VFQQPVIFLGADVTHPPAGDGKKPSITAVVGSMD-AHPSRYCATVRVQ 630

Query: 706 GAKVEMIDNLFKPVSDTEDEGIIRELLIDFYNSSGNRKPDNIIIFRDGVSESQFNQVLNI 765
             + E+I++L           ++RELLI FY S+   KP  II +RDGV E Q  Q+L+ 
Sbjct: 631 RPRQEIIEDL---------SYMVRELLIQFYKST-RFKPTRIIFYRDGVPEGQLPQILHY 680

Query: 766 ELSQIIEACKFLDEKWNPKFLVIVAQKNHHTKFF------QPGSPDNVPPGTVVDNKICH 819
           EL  I +AC  L++ + P    IV QK HHT+ F      + G   N+P GT VD  I H
Sbjct: 681 ELLAIRDACIKLEKDYQPGITYIVVQKRHHTRLFCADKNERIGKSGNIPAGTTVDTNITH 740

Query: 820 PRNYDFYMCAHAGMIGTSRPTHYHVLLDEIGFSPDDLQELVHSLSYVYQRSTTAISVVAP 879
           P  +DFY+C+HAG+ GTSRP+HY+VL D+  F+ D+LQ L + L + Y R T ++S+ AP
Sbjct: 741 PFEFDFYLCSHAGIQGTSRPSHYYVLWDDNRFTADELQILTYQLCHTYVRCTRSVSIPAP 800

Query: 880 ICYAHLAASQVGQFM--KFEDKSETSSSHGGS-GRDINA 915
             YA L A +    +  K  D  E S   G S GRD  A
Sbjct: 801 AYYARLVAFRARYHLVDKEHDSGEGSHISGQSNGRDPQA 839


>I2C4_MOUSE (Q8CJF8) Eukaryotic translation initiation factor 2C 4
           (eIF2C 4) (eIF-2C 4) (Piwi/argonaute family protain
           meIF2C4)
          Length = 861

 Score =  364 bits (934), Expect = e-100
 Identities = 270/885 (30%), Positives = 429/885 (47%), Gaps = 92/885 (10%)

Query: 67  PMARRGLGSKGAKLPLLTNHFKVNVTNTDGYFFQYSVALFYEDGRPVEGKGAGRKILDRV 126
           P  R GLG+ G  + LL NHF+V +   D Y +   +     + RP   +   R+++D +
Sbjct: 15  PPRRPGLGTVGKPIRLLANHFQVQIPKIDVYHYDVDIK---PEKRP---RRVNREVVDTM 68

Query: 127 QETYGSELNG-KDLAYDGEKTLFTIGSL--AQNKLEFTVVLEDVTSNRNNGNASPDGHGS 183
              +  ++ G +   YDG++ ++T   L   +++++  V L               G G 
Sbjct: 69  VRHFKMQIFGDRQPGYDGKRNMYTAHPLPIGRDRIDMEVTLP--------------GEG- 113

Query: 184 PNDTDRKRLKKSHRSKTYKVEISFASKIPLQAIANALKGHETENYQEAIRVLDIILRQHA 243
                        + +T+KV + + S   LQ +  AL GH  E   ++++ LD+I R H 
Sbjct: 114 -------------KDQTFKVSVQWVSVASLQLLLEALAGHLNEVPDDSVQALDVITR-HL 159

Query: 244 AKQGCLLVRQNFFHNDPKNFTDVGGGVLGCRGLHSSFRTTQSGLSLNIDVSTTMIVHPGP 303
                  V ++FF      +  +GGG     G H S R     + LNIDVS T      P
Sbjct: 160 PSMRYTPVGRSFFSPPEGYYHPLGGGREVWFGFHQSVRPAMWNMMLNIDVSATAFYRAQP 219

Query: 304 VVDFL-----IANQNVRDPFSLDWNKAKRT--LKNLRITTSPTNQ---EYKITGLSEMPC 353
           +++F+     I N N +     D  + K T  ++ L++  +   Q   +Y++  ++  P 
Sbjct: 220 IIEFMCEVLDIQNINEQTKPLTDSQRVKFTKEIRGLKVEVTHCGQMKRKYRVCNVTRRPA 279

Query: 354 KDQLFTLKKRGAVPGEDDTEEITVYDYFVNRRKISLQYSADLPCINVGKPKRPTFVPVEL 413
             Q F L+            E TV  YF  +  + L++   LPC+ VG+ ++ T++P+E+
Sbjct: 280 SHQTFPLQLENG-----QAMECTVAQYFKQKYSLQLKHP-HLPCLQVGQEQKHTYLPLEV 333

Query: 414 CSLVSLQRYTKALSTLQRSSLVEKSRQKPQERMRVLTDALKTSDY--GSEPMLRNCGISI 471
           C++V+ QR  K L+  Q S++++ + +   +R   ++  +K++    G +P L+  GI +
Sbjct: 334 CNIVAGQRCIKKLTDNQTSTMIKATARSAPDRQEEISRLVKSNSMVGGPDPYLKEFGIVV 393

Query: 472 TSGFTQVDGRVLQAPRLKFG--NGEDFNPRNGRWNFNNKKIVQPVKIEKWAVVNFSARCD 529
            +  T++ GRVL AP L++G  N     P  G W+   K+    ++I+ WAV  F+ +  
Sbjct: 394 HNEMTELTGRVLPAPMLQYGGRNKTVATPSQGVWDMRGKQFYAGIEIKVWAVACFAPQKQ 453

Query: 530 VR-----GLVRDLIKCGGMKGIHVE-QPFDCFEENGQFRRAPPLVRVEKMFEHVQSKLPG 583
            R          L K     G+ ++ QP  C       + A     VE MF+H++    G
Sbjct: 454 CREDLLKSFTDQLRKISKDAGMPIQGQPCFC-------KYAQGADSVEPMFKHLKMTYVG 506

Query: 584 APKFLLCLLSERKNSDLYGPWKKKNLAEFGIVTQCIAPTRV---NDQYLTNVLLKINAKL 640
               ++ L  +   + +Y   K+      G+ TQC+    V   + Q L+N+ LK+NAKL
Sbjct: 507 LQLIVVILPGK---TPVYAEVKRVGDTLLGMATQCVQIKNVVKTSPQTLSNLCLKMNAKL 563

Query: 641 GGMNSLLGVEHSPSIPIVSKAPTLILGMDVSHGSPGQTEIPSIAAVVSSRQWPLISKYRA 700
           GG+N++      PS   V + P + LG DV+H   G  + PSIAAVV S      S+Y A
Sbjct: 564 GGINNVPVPHQRPS---VFQQPVIFLGADVTHPPAGDGKKPSIAAVVGSMDGHP-SRYCA 619

Query: 701 CVRTQGAKVEMIDNLFKPVSDTED-EGIIRELLIDFYNSSGNRKPDNIIIFRDGVSESQF 759
            V  Q ++ E+   L       +D   + RELLI FY S+   KP  II +R GVSE Q 
Sbjct: 620 TVWVQTSRQEIAQELLYSQEVVQDLTSMARELLIQFYKST-RFKPTRIIYYRGGVSEGQM 678

Query: 760 NQVLNIELSQIIEACKFLDEKWNPKFLVIVAQKNHHTKFF------QPGSPDNVPPGTVV 813
            QV   EL  I +AC  L+E + P    IV QK HHT+ F      + G   NVP GT V
Sbjct: 679 KQVAWPELIAIRKACISLEEDYRPGITYIVVQKRHHTRLFCADKMERVGKSGNVPAGTTV 738

Query: 814 DNKICHPRNYDFYMCAHAGMIGTSRPTHYHVLLDEIGFSPDDLQELVHSLSYVYQRSTTA 873
           D+ + HP  +DFY+C+HAG+ GTSRP+HY VL D+  F+ D+LQ L + L + Y R T +
Sbjct: 739 DSTVTHPSEFDFYLCSHAGIQGTSRPSHYQVLWDDNCFTADELQLLTYQLCHTYVRCTRS 798

Query: 874 ISVVAPICYAHLAASQVGQFMKFEDKSETSSSH---GGSGRDINA 915
           +S+ AP  YA L A +    +  +D      SH     +GRD  A
Sbjct: 799 VSIPAPAYYARLVAFRARYHLVDKDHDSAEGSHVSGQSNGRDPQA 843


>I2C3_MOUSE (Q8CJF9) Eukaryotic translation initiation factor 2C 3
           (eIF2C 3) (eIF-2C 3) (Piwi/argonaute family protain
           meIF2C3)
          Length = 860

 Score =  363 bits (931), Expect = 1e-99
 Identities = 280/911 (30%), Positives = 436/911 (47%), Gaps = 103/911 (11%)

Query: 63  PTKVPMARRGLGSKGAKLPLLTNHFKVNVTNTDGYFFQYSVALFYEDGRPVEGKGAGRKI 122
           P  +   R G G+ G  + LL N F+V +   D Y ++  +     D  P   +   R++
Sbjct: 13  PLFIVPRRPGYGTMGKPIKLLANCFQVEIPKIDVYLYEVDIK---PDKCP---RRVNREV 66

Query: 123 LD-RVQETYGSELNGKDLAYDGEKTLFTIGSLAQNKLEFTVVLEDVTSNRNNGNASPDGH 181
           +D +VQ    +    +   YDG+++L+T   L    +  T V  DVT     G   P   
Sbjct: 67  VDSKVQHFKVTIFGDRRPVYDGKRSLYTANPLP---VATTGVDLDVTLPGEGGKDRP--- 120

Query: 182 GSPNDTDRKRLKKSHRSKTYKVEISFASKIPLQAIANALKGHETENYQEA--------IR 233
                              +KV + F S++    +  AL G       E         + 
Sbjct: 121 -------------------FKVSVKFVSRVSWHLLHEALAGGTLPEPLELDKPVSTNPVH 161

Query: 234 VLDIILRQHAAKQGCLLVRQNFFHNDPKNFTDVGGGVLGCRGLHSSFRTTQSGLSLNIDV 293
            +D++LR H        V ++FF         +GGG     G H S R     + LNIDV
Sbjct: 162 AVDVVLR-HLPSMKYTPVGRSFFSAPEGYDHPLGGGREVWFGFHQSVRPAMWKMMLNIDV 220

Query: 294 STTMIVHPGPVVDFL-----IANQNVRDPFSLDWNKAKRT--LKNLRITTS---PTNQEY 343
           S T      PV+ F+     I N + +     D ++ K T  +K L++  +      ++Y
Sbjct: 221 SATAFYKAQPVIQFMCEVLDIHNIDEQPRPLTDSHRVKFTKEIKGLKVEVTHCGTMRRKY 280

Query: 344 KITGLSEMPCKDQLFTLKKRGAVPGEDDTEEITVYDYFVNRRKISLQYSADLPCINVGKP 403
           ++  ++  P   Q F L+          T E TV  YF  +  + L+Y   LPC+ VG+ 
Sbjct: 281 RVCNVTRRPASHQTFPLQLENG-----QTVERTVAQYFREKYTLQLKYP-HLPCLQVGQE 334

Query: 404 KRPTFVPVELCSLVSLQRYTKALSTLQRSSLVEKSRQKPQERMRVLTDALKTSDYGSEPM 463
           ++ T++P+E+C++V+ QR  K L+  Q S++++ + +   +R   ++  +++++Y ++P 
Sbjct: 335 QKHTYLPLEVCNIVAGQRCIKKLTDNQTSTMIKATARSAPDRQEEISRLVRSANYETDPF 394

Query: 464 LRNCGISITSGFTQVDGRVLQAPRLKFG--NGEDFNPRNGRWNFNNKKIVQPVKIEKWAV 521
           ++   + +      V GRVL AP L++G  N     P +G W+   K+    V+I+ WA+
Sbjct: 395 VQEFQLKVRDEMAHVTGRVLPAPMLQYGGRNRTVATPSHGVWDMRGKQFHTGVEIKMWAI 454

Query: 522 VNFSARCDVR-----GLVRDLIKCGGMKGIHVE-QPFDCFEENGQFRRAPPLVRVEKMFE 575
             F+ +   R     G    L K     G+ ++ QP  C       + A     VE MF 
Sbjct: 455 ACFATQRQCREEILKGFTDQLRKISKDAGMPIQGQPCFC-------KYAQGADSVEPMFR 507

Query: 576 HVQSKLPGAPKFLLCLLSERKNSDLYGPWKKKNLAEFGIVTQCIAPTRV---NDQYLTNV 632
           H+++   G    ++ L  +   + +Y   K+      G+ TQC+    V   + Q L+N+
Sbjct: 508 HLKNTYSGLQLIIVILPGK---TPVYAEVKRVGDTLLGMATQCVQVKNVIKTSPQTLSNL 564

Query: 633 LLKINAKLGGMNSLLGVEHSPSIPIVSKAPTLILGMDVSHGSPGQTEIPSIAAVVSSRQW 692
            LKIN KLGG+N++L     PS   V + P + LG DV+H   G  + PSIAAVV S   
Sbjct: 565 CLKINVKLGGINNILVPHQRPS---VFQQPVIFLGADVTHPPAGDGKKPSIAAVVGSMD- 620

Query: 693 PLISKYRACVRTQGAKVEMIDNLFKPVSDTEDEGIIRELLIDFYNSSGNRKPDNIIIFRD 752
              S+Y A VR Q  + E+I +L           ++RELLI FY S+   KP  II +RD
Sbjct: 621 AHPSRYCATVRVQRPRQEIIQDL---------ASMVRELLIQFYKST-RFKPTRIIFYRD 670

Query: 753 GVSESQFNQVLNIELSQIIEACKFLDEKWNPKFLVIVAQKNHHTKFF------QPGSPDN 806
           GVSE QF QVL  EL  I EAC  L++ + P    IV QK HHT+ F      + G   N
Sbjct: 671 GVSEGQFRQVLYYELLAIREACISLEKDYQPGITYIVVQKRHHTRLFCADRTERVGRSGN 730

Query: 807 VPPGTVVDNKICHPRNYDFYMCAHAGMIGTSRPTHYHVLLDEIGFSPDDLQELVHSLSYV 866
           +P GT VD  I HP  +DFY+C+HAG+ GTSRP+HYHVL D+  F+ D+LQ L + L + 
Sbjct: 731 IPAGTTVDTDITHPYEFDFYLCSHAGIQGTSRPSHYHVLWDDNFFTADELQLLTYQLCHT 790

Query: 867 YQRSTTAISVVAPICYAHLAASQVGQFM--KFEDKSETSSSHGGS-GRDINASPIPQLPK 923
           Y R T ++S+ AP  YAHL A +    +  K  D +E S   G S GRD  A  + +  +
Sbjct: 791 YVRCTRSVSIPAPAYYAHLVAFRARYHLVDKEHDSAEGSHVSGQSNGRDPQA--LAKAVQ 848

Query: 924 LMDSVCNSMFF 934
           +      +M+F
Sbjct: 849 IHQDTLRTMYF 859


>I2C3_HUMAN (Q9H9G7) Eukaryotic translation initiation factor 2C 3
           (eIF2C 3) (eIF-2C 3) (Argonaute 3)
          Length = 860

 Score =  362 bits (928), Expect = 3e-99
 Identities = 282/929 (30%), Positives = 441/929 (47%), Gaps = 116/929 (12%)

Query: 45  PADIEPIKIEPQIVKKKLPTKVPMARRGLGSKGAKLPLLTNHFKVNVTNTDGYFFQYSVA 104
           PA  +P+ + P+             R G G+ G  + LL N F+V +   D Y ++  + 
Sbjct: 8   PAGAQPLLMVPR-------------RPGYGAMGKPIKLLANCFQVEIPKIDVYLYEVDIK 54

Query: 105 LFYEDGRPVEGKGAGRKILDRVQETYGSELNG-KDLAYDGEKTLFTIGSLAQNKLEFTVV 163
               D  P   +   R+++D + + +   + G +   YDG+++L+T   L    +  T V
Sbjct: 55  ---PDKCP---RRVNREVVDSMVQHFKVTIFGDRRPVYDGKRSLYTANPLP---VATTGV 105

Query: 164 LEDVTSNRNNGNASPDGHGSPNDTDRKRLKKSHRSKTYKVEISFASKIPLQAIANALKGH 223
             DVT     G   P                      +KV I F S++    +   L G 
Sbjct: 106 DLDVTLPGEGGKDRP----------------------FKVSIKFVSRVSWHLLHEVLTGR 143

Query: 224 ETENYQEA--------IRVLDIILRQHAAKQGCLLVRQNFFHNDPKNFTDVGGGVLGCRG 275
                 E         +  +D++LR H        V ++FF         +GGG     G
Sbjct: 144 TLPEPLELDKPISTNPVHAVDVVLR-HLPSMKYTPVGRSFFSAPEGYDHPLGGGREVWFG 202

Query: 276 LHSSFRTTQSGLSLNIDVSTTMIVHPGPVVDFL-----IANQNVRDPFSLDWNKAKRT-- 328
            H S R     + LNIDVS T      PV+ F+     I N + +     D ++ K T  
Sbjct: 203 FHQSVRPAMWKMMLNIDVSATAFYKAQPVIQFMCEVLDIHNIDEQPRPLTDSHRVKFTKE 262

Query: 329 LKNLRITTS---PTNQEYKITGLSEMPCKDQLFTLKKRGAVPGEDDTEEITVYDYFVNRR 385
           +K L++  +      ++Y++  ++  P   Q F L+          T E TV  YF  + 
Sbjct: 263 IKGLKVEVTHCGTMRRKYRVCNVTRRPASHQTFPLQLENG-----QTVERTVAQYFREKY 317

Query: 386 KISLQYSADLPCINVGKPKRPTFVPVELCSLVSLQRYTKALSTLQRSSLVEKSRQKPQER 445
            + L+Y   LPC+ VG+ ++ T++P+E+C++V+ QR  K L+  Q S++++ + +   +R
Sbjct: 318 TLQLKYP-HLPCLQVGQEQKHTYLPLEVCNIVAGQRCIKKLTDNQTSTMIKATARSAPDR 376

Query: 446 MRVLTDALKTSDYGSEPMLRNCGISITSGFTQVDGRVLQAPRLKFG--NGEDFNPRNGRW 503
              ++  +++++Y ++P ++     +      V GRVL AP L++G  N     P +G W
Sbjct: 377 QEEISRLVRSANYETDPFVQEFQFKVRDEMAHVTGRVLPAPMLQYGGRNRTVATPSHGVW 436

Query: 504 NFNNKKIVQPVKIEKWAVVNFSARCDVR-----GLVRDLIKCGGMKGIHVE-QPFDCFEE 557
           +   K+    V+I+ WA+  F+ +   R     G    L K     G+ ++ QP  C   
Sbjct: 437 DMRGKQFHTGVEIKMWAIACFATQRQCREEILKGFTDQLRKISKDAGMPIQGQPCFC--- 493

Query: 558 NGQFRRAPPLVRVEKMFEHVQSKLPGAPKFLLCLLSERKNSDLYGPWKKKNLAEFGIVTQ 617
               + A     VE MF H+++   G    ++ L  +   + +Y   K+      G+ TQ
Sbjct: 494 ----KYAQGADSVEPMFRHLKNTYSGLQLIIVILPGK---TPVYAEVKRVGDTLLGMATQ 546

Query: 618 CIAPTRV---NDQYLTNVLLKINAKLGGMNSLLGVEHSPSIPIVSKAPTLILGMDVSHGS 674
           C+    V   + Q L+N+ LKIN KLGG+N++L     PS   V + P + LG DV+H  
Sbjct: 547 CVQVKNVIKTSPQTLSNLCLKINVKLGGINNILVPHQRPS---VFQQPVIFLGADVTHPP 603

Query: 675 PGQTEIPSIAAVVSSRQWPLISKYRACVRTQGAKVEMIDNLFKPVSDTEDEGIIRELLID 734
            G  + PSIAAVV S      S+Y A VR Q  + E+I +L           ++RELLI 
Sbjct: 604 AGDGKKPSIAAVVGSMD-AHPSRYCATVRVQRPRQEIIQDL---------ASMVRELLIQ 653

Query: 735 FYNSSGNRKPDNIIIFRDGVSESQFNQVLNIELSQIIEACKFLDEKWNPKFLVIVAQKNH 794
           FY S+   KP  II +RDGVSE QF QVL  EL  I EAC  L++ + P    IV QK H
Sbjct: 654 FYKST-RFKPTRIIFYRDGVSEGQFRQVLYYELLAIREACISLEKDYQPGITYIVVQKRH 712

Query: 795 HTKFF------QPGSPDNVPPGTVVDNKICHPRNYDFYMCAHAGMIGTSRPTHYHVLLDE 848
           HT+ F      + G   N+P GT VD  I HP  +DFY+C+HAG+ GTSRP+HYHVL D+
Sbjct: 713 HTRLFCADRTERVGRSGNIPAGTTVDTDITHPYEFDFYLCSHAGIQGTSRPSHYHVLWDD 772

Query: 849 IGFSPDDLQELVHSLSYVYQRSTTAISVVAPICYAHLAASQVGQFM--KFEDKSETSSSH 906
             F+ D+LQ L + L + Y R T ++S+ AP  YAHL A +    +  K  D +E S   
Sbjct: 773 NCFTADELQLLTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVDKEHDSAEGSHVS 832

Query: 907 GGS-GRDINASPIPQLPKLMDSVCNSMFF 934
           G S GRD  A  + +  ++      +M+F
Sbjct: 833 GQSNGRDPQA--LAKAVQIHQDTLRTMYF 859


>I2C1_MOUSE (Q8CJG1) Eukaryotic translation initiation factor 2C 1
           (eIF2C 1) (eIF-2C 1) (Piwi/argonaute family protain
           meIF2C1)
          Length = 857

 Score =  357 bits (915), Expect = 1e-97
 Identities = 263/879 (29%), Positives = 433/879 (48%), Gaps = 98/879 (11%)

Query: 70  RRGLGSKGAKLPLLTNHFKVNVTNTDGYFFQYSVALFYEDGRPVEGKGAGRKILDRVQET 129
           R G+G+ G  + LL N+F+V++   D Y ++  +     D  P   +   R++++ + + 
Sbjct: 26  RPGIGTVGKPIKLLANYFEVDIPKIDVYHYEVDIK---PDKCP---RRVNREVVEYMVQH 79

Query: 130 YGSELNG-KDLAYDGEKTLFTIGSL--AQNKLEFTVVLEDVTSNRNNGNASPDGHGSPND 186
           +  ++ G +   YDG++ ++T+ +L     +++F V +               G G    
Sbjct: 80  FKPQIFGDRKPVYDGKENIYTVTALPIGNERVDFEVTIP--------------GEG---- 121

Query: 187 TDRKRLKKSHRSKTYKVEISFASKIPLQAIANALKGHETENYQEAIRVLDIILRQHAAKQ 246
                     + + +KV I + + +  + +  AL   +     E+++ LD+ +R H A  
Sbjct: 122 ----------KDRIFKVSIKWLAIVSWRMLHEALVSGQIPVPLESVQALDVAMR-HLASM 170

Query: 247 GCLLVRQNFFHNDPKNFTDVGGGVLGCRGLHSSFRTTQSGLSLNIDVSTTMIVHPGPVVD 306
               V ++FF      +  +GGG     G H S R     + LNIDVS T      PV++
Sbjct: 171 RYTPVGRSFFSPPEGYYHPLGGGREVWFGFHQSVRPAMWKMMLNIDVSATAFYKAQPVIE 230

Query: 307 FLIANQNVRD----PFSLDWNKAKR---TLKNLRITTSPTNQ---EYKITGLSEMPCKDQ 356
           F+    ++R+    P  L  ++  R    +K L++  +   Q   +Y++  ++  P   Q
Sbjct: 231 FMCEVLDIRNIDEQPKPLTDSQRVRFTKEIKGLKVEVTHCGQMKRKYRVCNVTRRPASHQ 290

Query: 357 LFTLKKRGAVPGEDDTEEITVYDYFVNRRKISLQYSADLPCINVGKPKRPTFVPVELCSL 416
            F L+          T E TV  +F  +  + L+Y   LPC+ VG+ ++ T++P+E+C++
Sbjct: 291 TFPLQLESG-----QTVECTVAQHFKQKYNLQLKYP-HLPCLQVGQEQKHTYLPLEVCNI 344

Query: 417 VSLQRYTKALSTLQRSSLVEKSRQKPQERMRVLTDALKTSDYGSEPMLRNCGISITSGFT 476
           V+ QR  K L+  Q S++++ + +   +R   ++  +K +    +P ++  GI +    T
Sbjct: 345 VAGQRCIKKLTDNQTSTMIKATARSAPDRQEEISRLMKNASCNLDPYIQEFGIKVKDDMT 404

Query: 477 QVDGRVLQAPRLKFG--NGEDFNPRNGRWNFNNKKIVQPVKIEKWAVVNFSARCDVR--- 531
           +V GRVL AP L++G  N     P  G W+   K+    ++I+ WA+  F+ +   R   
Sbjct: 405 EVTGRVLPAPILQYGGRNRAIATPNQGVWDMRGKQFYNGIEIKVWAIACFAPQKQCREEV 464

Query: 532 --GLVRDLIKCGGMKGIHVE-QPFDCFEENGQFRRAPPLVRVEKMFEHVQSKLPGAPKFL 588
                  L K     G+ ++ QP  C       + A     VE MF H+++   G    +
Sbjct: 465 LKNFTDQLRKISKDAGMPIQGQPCFC-------KYAQGADSVEPMFRHLKNTYSGLQLII 517

Query: 589 LCLLSERKNSDLYGPWKKKNLAEFGIVTQCIA---PTRVNDQYLTNVLLKINAKLGGMNS 645
           + L  +   + +Y   K+      G+ TQC+      + + Q L+N+ LKIN KLGG+N+
Sbjct: 518 VILPGK---TPVYAEVKRVGDTLLGMATQCVQVKNAVKTSPQTLSNLCLKINVKLGGINN 574

Query: 646 LLGVEHSPSIPIVSKAPTLILGMDVSHGSPGQTEIPSIAAVVSSRQWPLISKYRACVRTQ 705
           +L V H  S   V + P + LG DV+H   G  + PSI AVV S      S+Y A VR Q
Sbjct: 575 IL-VPHQRSA--VFQQPVIFLGADVTHPPAGDGKKPSITAVVGSMD-AHPSRYCATVRVQ 630

Query: 706 GAKVEMIDNLFKPVSDTEDEGIIRELLIDFYNSSGNRKPDNIIIFRDGVSESQFNQVLNI 765
             + E+I++L           ++RELLI FY S+   KP  II +RDGV E Q  Q+L+ 
Sbjct: 631 RPRQEIIEDL---------SYMVRELLIQFYKST-RFKPTRIIFYRDGVPEGQLPQILHY 680

Query: 766 ELSQIIEACKFLDEKWNPKFLVIVAQKNHHTKFF------QPGSPDNVPPGTVVDNKICH 819
           EL  I +AC  L++ + P    IV QK HHT+ F      + G   N+P GT VD  I H
Sbjct: 681 ELLAIRDACIKLEKDYQPGITYIVVQKRHHTRLFCADKNERIGKSGNIPAGTTVDTNITH 740

Query: 820 PRNYDFYMCAHAGMIGTSRPTHYHVLLDEIGFSPDDLQELVHSLSYVYQRSTTAISVVAP 879
           P  +DFY+C+HAG+ GTSRP+HY+VL D+  F+ D+LQ L + L + Y R T ++S+ AP
Sbjct: 741 PFEFDFYLCSHAGIQGTSRPSHYYVLWDDNRFTADELQILTYQLCHTYVRCTRSVSIPAP 800

Query: 880 ICYAHLAASQVGQFM--KFEDKSETSSSHGGS-GRDINA 915
             YA L A +    +  K  D  E S   G S GRD  A
Sbjct: 801 AYYARLVAFRARYHLVDKEHDSGEGSHISGQSNGRDPQA 839


>AGO1_SCHPO (O74957) Cell cycle control protein ago1 (RNA
           interference pathway protein ago1)
          Length = 834

 Score =  318 bits (816), Expect = 3e-86
 Identities = 232/741 (31%), Positives = 367/741 (49%), Gaps = 70/741 (9%)

Query: 183 SPNDTDRKRLKKSHRSKTYKVEISFA----SKIPLQAIANALKGHETENYQ--EAIRVLD 236
           S  D     +K +  S+++  EI F+    SKI L  ++  +    + + Q   +I  LD
Sbjct: 87  SKGDIADGTIKVNIGSESHPREIEFSIQKSSKINLHTLSQFVNSKYSSDPQVLSSIMFLD 146

Query: 237 IILRQHAAKQGCLLVRQNFFHNDPKNFTDVGGGVLGCRGLHSSFRTTQSGLSLNIDVSTT 296
           ++L++  ++        +FF  +  N   +GGGV   +G + S R  Q  +S+N+D+S++
Sbjct: 147 LLLKKKPSET-LFGFMHSFFTGE--NGVSLGGGVEAWKGFYQSIRPNQGFMSVNVDISSS 203

Query: 297 MIVHPGPVVDFLIAN---QNVRDPFSLDWNKAKRTLKNLRIT--------TSPTNQEYKI 345
                  ++  L+      NVRD    D  +  R  + L++T        T   N+ Y I
Sbjct: 204 AFWRNDSLLQILMEYTDCSNVRDLTRFDLKRLSRKFRFLKVTCQHRNNVGTDLANRVYSI 263

Query: 346 TGLSEMPCKDQLFTLKKRGAVPGEDDTEEITVYDYFVNRRKISLQYSADLPCINVGKPKR 405
            G S     D  F  +  G      + ++I+V +YF+    + LQY  +LPCI V   K 
Sbjct: 264 EGFSSKSASDSFFVRRLNG------EEQKISVAEYFLENHNVRLQYP-NLPCILV---KN 313

Query: 406 PTFVPVELCSLVSLQRYTKALSTLQRSSLVEKSRQKPQERMRVLTDALKTSDYGSEPMLR 465
              +P+E C +V  QRYT  L++ Q ++++  + Q+P ER++ + D +   D+ ++P L 
Sbjct: 314 GAMLPIEFCFVVKGQRYTAKLNSDQTANMIRFAVQRPFERVQQIDDFVHQMDWDTDPYLT 373

Query: 466 NCGISITSGFTQVDGRVLQAPRLKFGNGEDFNPRNGRWNFNNKKIVQPVK--IEKWAVVN 523
             G+ I     +V  RVL+ P +++G      P +GRWN   K+ + P +  I  WAV+ 
Sbjct: 374 QYGMKIQKKMLEVPARVLETPSIRYGGDCIERPVSGRWNLRGKRFLDPPRAPIRSWAVMC 433

Query: 524 FSA--RCDVRGLVRDL------IKCGGMKGIHVEQPFDCFEENGQFRRAPPLVRVEKMFE 575
           F++  R  +RG+   L      +   G+  +  + P    +  G        + + K  E
Sbjct: 434 FTSTRRLPMRGIENFLQTYVQTLTSLGINFVMKKPPVLYADIRGSVEEL--CITLYKKAE 491

Query: 576 HVQSKLPGAPKFLLCLLSERKNSDLYGPWKKKNLAEFGIVTQCIAPTRV---NDQYLTNV 632
            V +    AP   L  + ++ + + YG  K+      G+ +QC     +     QY  N+
Sbjct: 492 QVGN----APPDYLFFILDKNSPEPYGSIKRVCNTMLGVPSQCAISKHILQSKPQYCANL 547

Query: 633 LLKINAKLGGMNSLLGVEHSPSIPIVSKAPTLILGMDVSHGSPGQTEIPSIAAVVSSRQW 692
            +KIN K+GG+N  L  + +P    +   PTLILG DV H   G T + SIA++V+S   
Sbjct: 548 GMKINVKVGGINCSLIPKSNP----LGNVPTLILGGDVYHPGVGATGV-SIASIVASVDL 602

Query: 693 PLISKYRACVRTQGAKVEMIDNLFKPVSDTEDEGIIRELLIDFYNSSGNRKPDNIIIFRD 752
               KY A  R+Q    E+I+ +         + I+  LL  F  +   ++P  II FRD
Sbjct: 603 NGC-KYTAVSRSQPRHQEVIEGM---------KDIVVYLLQGF-RAMTKQQPQRIIYFRD 651

Query: 753 GVSESQFNQVLNIELSQIIEACKFLDEKWNPKFLVIVAQKNHHTKFFQPGSPD-----NV 807
           G SE QF  V+N ELSQI EAC  L  K+NPK LV   QK HH +FF     D     N 
Sbjct: 652 GTSEGQFLSVINDELSQIKEACHSLSPKYNPKILVCTTQKRHHARFFIKNKSDGDRNGNP 711

Query: 808 PPGTVVDNKICHPRNYDFYMCAHAGMIGTSRPTHYHVLLDEIGFSPDDLQELVHSLSYVY 867
            PGT+++  + HP  YDFY+ +H  + G S P HY VL DEI   PD  Q L ++L YVY
Sbjct: 712 LPGTIIEKHVTHPYQYDFYLISHPSLQGVSVPVHYTVLHDEIQMPPDQFQTLCYNLCYVY 771

Query: 868 QRSTTAISVVAPICYAHLAAS 888
            R+T+A+S+V P+ YAHL ++
Sbjct: 772 ARATSAVSLVPPVYYAHLVSN 792


>YO43_CAEEL (P34681) Hypothetical protein ZK757.3 in chromosome III
          Length = 1040

 Score =  258 bits (659), Expect = 5e-68
 Identities = 175/567 (30%), Positives = 290/567 (50%), Gaps = 45/567 (7%)

Query: 343 YKITGLSEMPCKDQLFTLKKRGAVPGEDDTEEITVYDYFVNRRKISLQYSADLPCINVGK 402
           YK+  L ++P    +F       +  E      +V DYF + +   L+Y   LPC++VG 
Sbjct: 419 YKVNSL-QLPADKLMFQ-----GIDEEGRQVVCSVADYF-SEKYGPLKYPK-LPCLHVGP 470

Query: 403 PKRPTFVPVELCSLVSLQRYTKALSTLQRSSLVEKSRQKPQERMRVLTDALKTSDYGSEP 462
           P R  F+P+E C + S Q+Y K +S  Q S++++ +     +R   +      + +G++P
Sbjct: 471 PTRNIFLPMEHCLIDSPQKYNKKMSEKQTSAIIKAAAVDATQREDRIKQLAAQASFGTDP 530

Query: 463 MLRNCGISITSGFTQVDGRVLQAPRLKFG-NGEDFNP----RNGRWNFNNKKIVQPVKIE 517
            L+  G++++S   Q   RV+Q P + FG N    NP    ++G W  +N+ +  P    
Sbjct: 531 FLKEFGVAVSSQMIQTTARVIQPPPIMFGGNNRSVNPVVFPKDGSWTMDNQTLYMPATCR 590

Query: 518 KWAVVNFSARCDVRGLVRDLIKCGGMKGIHVEQPFDCFEENGQFRRAPPLVRVEKMFEHV 577
            ++++      D   L +   +   MK   +   F  + +  ++ R+   V    +F  +
Sbjct: 591 SYSMIALVDPRDQTSL-QTFCQSLTMKATAMGMNFPRWPDLVKYGRSKEDVCT--LFTEI 647

Query: 578 QSKLPGAPKFLLCLLS--ERKNSDLYGPWKKKNLAEFGIVTQCIAPTRVN---DQYLTNV 632
             +         C++   + KNSD+Y   K+++    GI++QC+    V+        N+
Sbjct: 648 ADEYRVTNTVCDCIIVVLQSKNSDIYMTVKEQSDIVHGIMSQCVLMKNVSRPTPATCANI 707

Query: 633 LLKINAKLGGMNSLLGVEHSPSIPIVSKAPTLILGMDVSHGSPGQTEI----PSIAAVVS 688
           +LK+N K+GG+NS +  +   +  +V + PT+++G+DV+H  P Q E+    PS+AA+V+
Sbjct: 708 VLKLNMKMGGINSRIVADKITNKYLVDQ-PTMVVGIDVTH--PTQAEMRMNMPSVAAIVA 764

Query: 689 SRQWPLISKYRACVRTQGAKVEMIDNLFKPVSDTEDEGIIRELLIDFYNSSGNRKPDNII 748
           +    L   Y A V+ Q    E +  L            IRE +I FY  +  +KP  II
Sbjct: 765 NVDL-LPQSYGANVKVQKKCRESVVYLLDA---------IRERIITFYRHT-KQKPARII 813

Query: 749 IFRDGVSESQFNQVLNIELSQIIEACKFLDEKWNPKFLVIVAQKNHHTKFF------QPG 802
           ++RDGVSE QF++VL  E+  I  AC  + E + P    IV QK HH + F        G
Sbjct: 814 VYRDGVSEGQFSEVLREEIQSIRTACLAIAEDFRPPITYIVVQKRHHARIFCKYQNDMVG 873

Query: 803 SPDNVPPGTVVDNKICHPRNYDFYMCAHAGMIGTSRPTHYHVLLDEIGFSPDDLQELVHS 862
              NVPPGT VD  I  P  +DFY+C+H G+ GTSRP  YHVLLDE  F+ D++Q + + 
Sbjct: 874 KAKNVPPGTTVDTGIVSPEGFDFYLCSHYGVQGTSRPARYHVLLDECKFTADEIQSITYG 933

Query: 863 LSYVYQRSTTAISVVAPICYAHLAASQ 889
           + + Y R T ++S+  P+ YA L A++
Sbjct: 934 MCHTYGRCTRSVSIPTPVYYADLVATR 960



 Score = 45.8 bits (107), Expect = 5e-04
 Identities = 52/199 (26%), Positives = 84/199 (42%), Gaps = 29/199 (14%)

Query: 45  PADIEPIKIEPQIVKKKLPTKVPMARRGLGSKGAKLPLLTNHFKVNVTNTDGYFFQYSVA 104
           P D+ P+ +        L  +  +AR GLG+ G ++P+ +N F +++ N      QY V 
Sbjct: 67  PRDLSPLLLSELAC---LNMREVVARPGLGTIGRQIPVKSNFFAMDLKNPKMVVIQYHVE 123

Query: 105 LFYEDGRPVEGKGAGRKILDRVQETYGSELNGK-DLAYDGEKTLFTIGSLAQNKLEFTVV 163
           + +   R ++ K   R I  +    + +  + K  LAYDG   L+T+      +LEF   
Sbjct: 124 IHHPGCRKLD-KDEMRIIFWKAVSDHPNIFHNKFALAYDGAHQLYTVA-----RLEF--- 174

Query: 164 LEDVTSNRNNGNASPDGHGSPNDTDRKRLKKSHRSKTYKVEISFASKIP-LQAIANALKG 222
                         PD  GS        L K +R +T +  IS  +  P L  +      
Sbjct: 175 --------------PDDQGSVRLDCEASLPKDNRDRT-RCAISIQNVGPVLLEMQRTRTN 219

Query: 223 HETENYQEAIRVLDIILRQ 241
           +  E     I++LDII RQ
Sbjct: 220 NLDERVLTPIQILDIICRQ 238


>AGO2_DROME (Q9VUQ5) Argonaute 2 protein
          Length = 1214

 Score =  251 bits (642), Expect = 5e-66
 Identities = 204/786 (25%), Positives = 355/786 (44%), Gaps = 95/786 (12%)

Query: 133  ELNGKDLAYDGEKTLFTIGSLAQNKLEFTVVLEDVTSNRNNGNASPDGHGSPNDTDRKRL 192
            +L G  LAYDG+ + +++  L  N         +VT    NG                  
Sbjct: 459  QLGGAVLAYDGKASCYSVDKLPLNSQN-----PEVTVTDRNG------------------ 495

Query: 193  KKSHRSKTYKVEISFA--SKIPLQAIANALKGHETENYQEAIRVLDIILRQHAAKQGCLL 250
                R+  Y +EI     S I L+++   +     +    A++ ++++L      +   +
Sbjct: 496  ----RTLRYTIEIKETGDSTIDLKSLTTYMNDRIFDKPMRAMQCVEVVLASPCHNKAIRV 551

Query: 251  VRQNFFHNDPKNFTDVGGGVLGCRGLHSSFRTTQSGLSLNIDVSTTMIVHPGPVVDFL-- 308
             R  F  +DP N  ++  G     GL+ +F        LN+D+S        P++++L  
Sbjct: 552  GRSFFKMSDPNNRHELDDGYEALVGLYQAFMLGDRPF-LNVDISHKSFPISMPMIEYLER 610

Query: 309  -IANQNVRDPFSLDWNKA--KRTLKNLRITTSPTN------QEYKITGLSEMPCKDQLFT 359
                  + +  +LD+++   +  L+ + +  +P        + Y++ GLS  P   + F 
Sbjct: 611  FSLKAKINNTTNLDYSRRFLEPFLRGINVVYTPPQSFQSAPRVYRVNGLSRAPASSETF- 669

Query: 360  LKKRGAVPGEDDTEEITVYDYFVNRRKISLQYSADLPCINVGKPKRPTFVPVELCSLVSL 419
                     E D +++T+  YF + R   L++   L C+NVG   +   +P+ELCS+   
Sbjct: 670  ---------EHDGKKVTIASYF-HSRNYPLKFP-QLHCLNVGSSIKSILLPIELCSIEEG 718

Query: 420  QRYTKALSTLQRSSLVEKSRQKPQERMRVLTDALKTSDYGSEPMLRNCGISITSGFTQVD 479
            Q   +     Q +++++ +      R R + + L+   +  +P +   GI I + F  V 
Sbjct: 719  QALNRKDGATQVANMIKYAATSTNVRKRKIMNLLQYFQHNLDPTISRFGIRIANDFIVVS 778

Query: 480  GRVLQAPRLKFGNGEDFNPRNGRWNFNNKKIVQPV-KIEKWAVVNFSARCDVRGLVRDLI 538
             RVL  P++++ +      +NG W  +  K ++P  K  K AV+    R   +     L 
Sbjct: 779  TRVLSPPQVEYHSKRFTMVKNGSWRMDGMKFLEPKPKAHKCAVLYCDPRSGRKMNYTQLN 838

Query: 539  KCGGM-----KGIHVEQPFDCFEENGQFRRAPPLVRVEKMFEHVQSKLPGAPKFLLCLLS 593
              G +     K +++    D            P    E+  + + + L  +   L  ++ 
Sbjct: 839  DFGNLIISQGKAVNISLDSDVTYR--------PFTDDERSLDTIFADLKRSQHDLAIVII 890

Query: 594  ERKNSDLYGPWKKKNLAEFGIVTQCIAPTRV----NDQYLTNVLLKINAKLGGMNSLLGV 649
             +     Y   K+K   + GI+TQCI    V    N+Q + N+LLKIN+KL G+N    +
Sbjct: 891  PQFRIS-YDTIKQKAELQHGILTQCIKQFTVERKCNNQTIGNILLKINSKLNGINHK--I 947

Query: 650  EHSPSIPIVSKAPTLILGMDVSHGSPGQTEIPSIAAVVSSRQWPLISKYRACVRTQGAKV 709
            +  P +P++    T+ +G DV+H SP Q EIPS+  V +S   P  + Y    R Q   +
Sbjct: 948  KDDPRLPMMKN--TMYIGADVTHPSPDQREIPSVVGVAASHD-PYGASYNMQYRLQRGAL 1004

Query: 710  EMIDNLFKPVSDTEDEGIIRELLIDFYNSSGNRKPDNIIIFRDGVSESQFNQVLNIELSQ 769
            E I+++F    +           +  Y    N  PD+II +RDGVS+ QF ++ N EL  
Sbjct: 1005 EEIEDMFSITLEH----------LRVYKEYRNAYPDHIIYYRDGVSDGQFPKIKNEELRC 1054

Query: 770  IIEACKFLDEKWNPKFLVIVAQKNHHTKFFQPGSP------DNVPPGTVVDNKICHPRNY 823
            I +AC  +  K  PK   ++  K HHT+FF  G        +NV PGTVVD  I HP   
Sbjct: 1055 IKQACDKVGCK--PKICCVIVVKRHHTRFFPSGDVTTSNKFNNVDPGTVVDRTIVHPNEM 1112

Query: 824  DFYMCAHAGMIGTSRPTHYHVLLDEIGFSPDDLQELVHSLSYVYQRSTTAISVVAPICYA 883
             F+M +H  + GT++PT Y+V+ +      D LQ+L ++L +++ R   ++S  AP   A
Sbjct: 1113 QFFMVSHQAIQGTAKPTRYNVIENTGNLDIDLLQQLTYNLCHMFPRCNRSVSYPAPAYLA 1172

Query: 884  HLAASQ 889
            HL A++
Sbjct: 1173 HLVAAR 1178


>PIWI_BRARE (Q8UVX0) Piwi protein
          Length = 858

 Score =  158 bits (400), Expect = 6e-38
 Identities = 150/589 (25%), Positives = 261/589 (43%), Gaps = 69/589 (11%)

Query: 327 RTLKNLRITTSPTNQEYKITGLSEMPCKDQLFTLKKRGAVPGEDDTEEITVYDYFVNRRK 386
           + L  L I T   N+ Y+I  ++     +  F   K+G      DTE I+  +YF ++  
Sbjct: 299 KELVGLIILTKYNNKTYRIDDIAWDHTPNNTF---KKG------DTE-ISFKNYFKSQYG 348

Query: 387 ISLQYSADLPCINVGK--------PKRPTFVPVELCSLVSLQRYTKALSTLQRSSLVEKS 438
           + +     +  ++  K        P  P  +  E C L  L    +A   + +  L   +
Sbjct: 349 LDITDGNQVLLVSHVKRLGPSGRPPPGPAMLVPEFCYLTGLTDKMRADFNIMKD-LASHT 407

Query: 439 RQKPQERM----RVLTDALKTSDYGSEPMLRNCGISITSGFTQVDGRVLQAPRL-KFGNG 493
           R  P++R     R++++  +  D  +E  L   G+S  +    ++GRVL + R+ + G  
Sbjct: 408 RLSPEQREGRINRLISNINRNGDVQNE--LTTWGLSFENKLLSLNGRVLPSERIIQGGRA 465

Query: 494 EDFNPRNGRWN--FNNKKIVQPVKIEKWAVVNFSARCDV-RGLVRDLIKCGGMKGIHVEQ 550
            ++NP    W+       ++  + ++ W +       DV + L++ L K  G  GI +++
Sbjct: 466 FEYNPWTADWSKEMRGLPLISCMSLDNWLMFYTRRNADVAQSLLQTLNKVSGPMGIRMQR 525

Query: 551 PFDCFEENGQFRRAPPLVRVEKMFEHVQSKLPGAPKFLLCLLSERKNSDLYGPWKKKNLA 610
                 E+ Q          E +   +Q  +    + ++ +L   +  D Y   KK    
Sbjct: 526 AVMIEYEDRQ----------ESLLRALQQNVARETQMVVVILPTNRK-DKYDCVKKYLCV 574

Query: 611 EFGIVTQCIAPTRVNDQYL-----TNVLLKINAKLGGMNSLLGVEHSPSIPIVSKAPTLI 665
           +    +QC+    ++         T + L++N K+GG   L  VE    IP+      +I
Sbjct: 575 DCPTPSQCVVSRTISKPQALMTVATKIALQMNCKMGG--ELWSVE----IPL---RQLMI 625

Query: 666 LGMDVSHGSPGQTEIPSIAAVVSSRQWPLISKYRACVRTQGAKVEMIDNLFKPVSDTEDE 725
           +G+D  H +       SI A+V+S    +   +  CV  Q    E+ID L         +
Sbjct: 626 VGIDCYHDTAAGKR--SIGAMVASLNQGMSRWFSKCV-LQNRGQEIIDAL---------K 673

Query: 726 GIIRELLIDFYNSSGNRKPDNIIIFRDGVSESQFNQVLNIELSQIIEACKFLDEKWNPKF 785
           G ++  L   Y    N  P  II++RDGV +     V++ E+ QI+++ K + + + PK 
Sbjct: 674 GSLQGAL-KAYLKYNNSLPSRIIVYRDGVGDGMLQSVVDYEVPQIMQSIKTMGQDYEPKL 732

Query: 786 LVIVAQKNHHTKFFQ--PGSPDNVPPGTVVDNKICHPRNYDFYMCAHAGMIGTSRPTHYH 843
            V+V +K   ++FF    G   N PPGTV+D ++  P  YDF++ + A   G   PTHY+
Sbjct: 733 SVVVVKKRISSRFFARIDGKIANPPPGTVIDTEVTRPEWYDFFIVSQAVRFGCVAPTHYN 792

Query: 844 VLLDEIGFSPDDLQELVHSLSYVYQRSTTAISVVAPICYAHLAASQVGQ 892
           V+ D  G  PD +Q L + L ++Y      + V AP  YAH  A  VGQ
Sbjct: 793 VVFDNSGLKPDHMQRLTYKLCHMYYNWQGIVRVPAPCQYAHKLAFLVGQ 841


>PIWI_DROME (Q9VKM1) Piwi protein
          Length = 843

 Score =  140 bits (352), Expect = 2e-32
 Identities = 156/682 (22%), Positives = 300/682 (43%), Gaps = 72/682 (10%)

Query: 232 IRVLDIILRQHAAKQGCLLVRQNFFHNDPKNFTDVGGGVLGC-RGLHSSFRTTQSGLSLN 290
           ++VL++ILR+        LV +N F  DP+   ++    +    G  +S R  +  + L 
Sbjct: 194 LQVLNLILRRSMKGLNLELVGRNLF--DPRAKIEIREFKMELWPGYETSIRQHEKDILLG 251

Query: 291 IDVSTTMIVHPGPVVDFLIANQNVRDPFSLDWNKAKRTLKNLRITTSPTNQEYKITGLSE 350
            ++ T  ++    + D  I  +   +P +   ++ +  + +L + T   N+ Y+I  +  
Sbjct: 252 TEI-THKVMRTETIYD--IMRRCSHNP-ARHQDEVRVNVLDLIVLTDYNNRTYRINDVDF 307

Query: 351 MPCKDQLFTLKKRGAVPGEDDTEEITVYDYFVNRRKISLQYSADLPCINVGKPKR----- 405
                  F+ K R          +I+  +Y++ +  I ++       I+  + K      
Sbjct: 308 GQTPKSTFSCKGR----------DISFVEYYLTKYNIRIRDHNQPLLISKNRDKALKTNA 357

Query: 406 ---PTFVPVELCSLVSLQRYTKALSTLQR--SSLVEKSRQKPQERMRVLTDALKTSDYGS 460
                 +P ELC +  L    ++   L R  SS    + ++  +R+R     L+ +   S
Sbjct: 358 SELVVLIP-ELCRVTGLNAEMRSNFQLMRAMSSYTRMNPKQRTDRLRAFNHRLQNTPE-S 415

Query: 461 EPMLRNCGISITSGFTQVDGRVLQAPRLKFGNGEDFNPRNGRW--NFNNKKIVQPVK--I 516
             +LR+  + +    T+V GR++    + F NG+     N  W  +F +++++      +
Sbjct: 416 VKVLRDWNMELDKNVTEVQGRIIGQQNIVFHNGKVPAGENADWQRHFRDQRMLTTPSDGL 475

Query: 517 EKWAVVNFSARC-DVRGLVRDLIKCGGMKGIHVEQPFDCF---EENGQFRRAPPLVRVEK 572
           ++WAV+       ++R L+  L +     G+ +  P +     +  G + RA        
Sbjct: 476 DRWAVIAPQRNSHELRTLLDSLYRAASGMGLRIRSPQEFIIYDDRTGTYVRA-------- 527

Query: 573 MFEHVQSKLPGAPKFLLCLLSERKNSDLYGPWKKKNLAEFGIVTQCIAPTRVNDQYLTNV 632
           M + V+S     PK +LCL+    N++ Y   KK+   +  + TQ +      ++ L ++
Sbjct: 528 MDDCVRSD----PKLILCLVPN-DNAERYSSIKKRGYVDRAVPTQVVTLKTTKNRSLMSI 582

Query: 633 LLKINAKLGGMNSLLGVEHSPSIPIVSKAPTLILGMDVSHGSPGQTEIPSIAAVVSSRQW 692
             KI  +L   N  LG  ++P +  +  +  + +G D++  +  +    +  A+++S   
Sbjct: 583 ATKIAIQL---NCKLG--YTPWMIELPLSGLMTIGFDIAKSTRDRKR--AYGALIASMDL 635

Query: 693 PLISKYRACVRTQGAKVEMIDNLFKPVSDTEDEGIIRELLIDFYNSSGNRKPDNIIIFRD 752
              S Y + V T+ +  +++ N   P+        I + L   Y     + P  I+ +RD
Sbjct: 636 QQNSTYFSTV-TECSAFDVLANTLWPM--------IAKALRQ-YQHEHRKLPSRIVFYRD 685

Query: 753 GVSESQFNQVLNIELSQIIEACKFLDEKWN---PKFLVIVAQKNHHTKFFQPGSPDNVPP 809
           GVS     Q+   E+  IIE  K    +     P+   IV  ++ +T+FF  G   N PP
Sbjct: 686 GVSSGSLKQLFEFEVKDIIEKLKTEYARVQLSPPQLAYIVVTRSMNTRFFLNGQ--NPPP 743

Query: 810 GTVVDNKICHPRNYDFYMCAHAGMIGTSRPTHYHVLLDEIGFSPDDLQELVHSLSYVYQR 869
           GT+VD+ I  P  YDFY+ +     GT  PT Y+VL   +G SP+ +Q+L + + ++Y  
Sbjct: 744 GTIVDDVITLPERYDFYLVSQQVRQGTVSPTSYNVLYSSMGLSPEKMQKLTYKMCHLYYN 803

Query: 870 STTAISVVAPICYAHLAASQVG 891
            +    V A   YA   A+ VG
Sbjct: 804 WSGTTRVPAVCQYAKKLATLVG 825


>GCC7_CAEEL (Q21770) Germ cell expressed protein R06C7.1
          Length = 945

 Score = 94.4 bits (233), Expect = 1e-18
 Identities = 183/809 (22%), Positives = 313/809 (38%), Gaps = 120/809 (14%)

Query: 135 NGKDLAYDGEKTLFTIGSLAQNKLEFTVVLEDVTSNRNNGNASPDGHGSPNDTDRKRLKK 194
           +G  + YDG+ TL+T  +L            ++ +N               + D K L  
Sbjct: 148 DGNQIVYDGQSTLYTTVNL----------FSELDANGTKSKVFQINGADTGNDDLKTLP- 196

Query: 195 SHRSKTYKVEISFASKIPLQAIANALKGHETE------NYQEAIRVLDIILRQHAAKQ-- 246
                   +EI +A +     +++   G  T       N +E  + L++ L QH  ++  
Sbjct: 197 -----CISLEI-YAPRDNSITLSSENLGKRTADQNIEVNNREYTQFLELALNQHCVRETN 250

Query: 247 --GCLLVRQNFFHN------DPKNFTDVGGGVLGCRGLHSSFRTT-------QSGLSLNI 291
             GC    + +F N      D ++  DVG G     GL  + +         Q+  SL I
Sbjct: 251 RFGCFEHGKVYFLNATEEGFDQRDCVDVGDGKQLYPGLKKTIQFIEGPYGRGQNNPSLVI 310

Query: 292 DVSTTMIVHPGPVVD--FLIANQNVRDPFS-LDWNKAKRTLKNLRITTSPTNQE--YKIT 346
           D           V+   F I  Q+  +  + +   KA   +K L   ++ TN++   +I 
Sbjct: 311 DGMKAAFHKEQTVIQKLFDITGQDPSNGLNNMTREKAAAVIKGLDCYSTYTNRKRHLRIE 370

Query: 347 GLSEMPCKDQLFTLKKRGAVPGEDDTEEITVYDYFVNRRKISLQY-SADLP-CINVGKPK 404
           G+         F L          D +  ++ +Y+ ++ KISLQY +A+L  C + G   
Sbjct: 371 GIFHESATKTRFELP---------DGKTCSIAEYYADKYKISLQYPNANLVVCKDRGNNN 421

Query: 405 RPTFVPVELCSLVSLQRYTKALSTLQRSSLVEKS-RQKPQERMRVLTDALKTSDYGSE-P 462
              + P EL ++   QR T    T  +S    K     P  R R++       +   E  
Sbjct: 422 ---YFPAELMTVSRNQRVTIPQQTGNQSQKTTKECAVLPDVRQRMIITGKNAVNITLENE 478

Query: 463 MLRNCGISITSGFTQVDGRVLQAPRLKFGNGEDFNPRNGRWNFNNKKIVQPVKIEK---- 518
           +L   GI + S    V  R L    L +      +   G+W       V+P  +      
Sbjct: 479 LLVALGIKVYSEPLMVQARELDGKELVYQRSVMSDM--GKWRAPPGWFVKPATVPDLWAA 536

Query: 519 WAVVNFSARC---DVRGLVRDLIKCGGMKGIHVEQPFDCFEENGQFRRAPPLVRVEKMFE 575
           +AV N   R    DV  LV   I     KG+ ++ P     E G       L   EK+  
Sbjct: 537 YAVGNPGCRFSIGDVNQLVGMFIDSCKKKGMVIKPPC----ETG-------LYSTEKIMT 585

Query: 576 HVQSKLPGAPKFLLCLLSERKNSDLYGPWKKKNLAEFGIVTQCIAPTRVNDQY------- 628
            ++       K++L ++++     L+  +K        IV Q +  ++ N          
Sbjct: 586 QLEKVAASKCKYVL-MITDDAIVHLHKQYKALEQRTMMIV-QDMKISKANAVVKDGKRLT 643

Query: 629 LTNVLLKINAKLGGMNSLLGVEHSPSIPIVSKAPT---LILGMDVSHGSPGQTEIPSIAA 685
           L N++ K N KLGG+N         ++    K+ T   LI+G+ VS  +P     P+   
Sbjct: 644 LENIINKTNVKLGGLNY--------TVSDAKKSMTDEQLIIGVGVS--AP-----PAGTK 688

Query: 686 VVSSRQWPLISKYRACVRTQGAKVEMIDNLFKPVSDTEDEGIIRELL---IDFYNSSGNR 742
            +   +  L  +         A  E + +     S  +    I ++L   ID +  +   
Sbjct: 689 YMMDNKGHLNPQIIGFASNAVANHEFVGDFVLAPSGQDTMASIEDVLQNSIDLFEKNRKA 748

Query: 743 KPDNIIIFRDGVSESQFNQVLNIELSQIIEACKFLDEKWNPKFLVIVAQKNHHTKFFQP- 801
            P  III+R G SE     +L  E+           ++   K + IV  K H  +FF+  
Sbjct: 749 LPKRIIIYRSGASEGSHASILAYEIPLARAIIHGYSKEI--KLIFIVVTKEHSYRFFRDQ 806

Query: 802 ------GSPDNVPPGTVVDNKICHPRNYDFYMCAHAGMIGTSRPTHYHVLLDEIGFSPDD 855
                  +  N+PPG V+DN + +P    F++  H  + GT++   Y VL D+     D 
Sbjct: 807 LRSGGKATEMNIPPGIVLDNAVTNPACKQFFLNGHTTLQGTAKTPLYTVLADDCKAPMDR 866

Query: 856 LQELVHSLSYVYQRSTTAISVVAPICYAH 884
           L+EL  +L + +Q  + + S+  P+  A+
Sbjct: 867 LEELTFTLCHHHQIVSLSTSIPTPLYVAN 895


>YQ53_CAEEL (Q09249) Hypothetical protein C16C10.3 in chromosome III
          Length = 1032

 Score = 91.7 bits (226), Expect = 8e-18
 Identities = 121/577 (20%), Positives = 239/577 (40%), Gaps = 76/577 (13%)

Query: 344 KITGLSEMPCKDQLFTLKKRGAVPGEDDTEEITVYDYFVNRRKISLQYSADLPCINVGKP 403
           +++ ++E   ++  F +K       +    E+TV +YF+ +  I L+Y   LP +   + 
Sbjct: 414 RVSSIAENNAENTSFMMKD------DKGEREVTVAEYFLLQYNIKLKYPR-LPLVVSKRF 466

Query: 404 KRPTFVPVELCSLVSLQRY-TKALSTLQRSSLVEKSRQKPQERMRVLTDALKTS-DYGSE 461
           K  +F P+EL  +   QR     +S   +S++  ++   PQ  ++++ D L+ +      
Sbjct: 467 KHESFFPMELLRIAPGQRIKVNKMSPTVQSAMTGRNASMPQHHVKLVQDILRDNLKLEQN 526

Query: 462 PMLRNCGISITSGFT-QVDGRVLQAPRLKFGNGEDFNPRNGRWNFNNK-KIVQPVKIEKW 519
             +   GI + S    Q+  ++L   ++KF  G+ + P   R  F  + K V+P +I K 
Sbjct: 527 KYMDAFGIKLMSTEPIQMTAKLLPPAQIKF-KGQTYMPDMSRPAFRTQDKFVEPARIRKI 585

Query: 520 AVVNFSARCDVRGLVRDLIKCGGM---KGIHVEQPFDCFEENGQFRRAPPLVRVEKMFEH 576
            +V F     +R       K        GI VE+  D  + + +   +   V ++ + + 
Sbjct: 586 GIVVFDNCIQMRQAEDFCDKLSNFCRDNGITVEK--DSRDWSIRELNSSDSVAIQNLMK- 642

Query: 577 VQSKLPGAPKFLLCLLSERKNSDLYGPWKKKNLAEFGIVTQCIAPTRVND--------QY 628
              K       +L  ++  K  D++   K       G+ T  +    V+         Q 
Sbjct: 643 ---KWLDDRVDILVGIAREKKPDVHDILKYFE-ESIGLQTIQLCQQTVDKMMGGQGGRQT 698

Query: 629 LTNVLLKINAKLGGMNSLLGVEHSP-SIPIVSKAPTL---------ILGMDVSHGSP--- 675
           + NV+ K N K GG N  + + ++     + S   TL          +G ++SHG+    
Sbjct: 699 IDNVMRKFNLKCGGTNFFVEIPNAVRGKAVCSNNETLRKKLLEHVQFIGFEISHGASRTL 758

Query: 676 ---------GQTEIPSIA-AVVSSRQWPLISKYRACVRTQGAKVEMIDNLFKPVSDTEDE 725
                    G+  +  ++ ++ +S Q   +  +      +  K++ +D  F         
Sbjct: 759 FDRSRSQMDGEPSVVGVSYSLTNSTQ---LGGFTYLQTQKEYKLQKLDEFFPKC------ 809

Query: 726 GIIRELLIDFYNSSGNRKPDNIIIFRDGVSESQFNQVLNIELSQIIEACKFLDEKWNPKF 785
                  +  Y       P  I+I+R G  E  FN+V   E+ ++      +   + P  
Sbjct: 810 -------VRSYKEHSKTLPTRIVIYRVGAGEGNFNRVKE-EVEEMRRTFDKIQPGYRPHL 861

Query: 786 LVIVAQKNHHTKFFQP------GSPDNVPPGTVVDNKICHPRNYDFYMCAHAGMIGTSRP 839
           +VI+AQ+  H + F         +  N+P GT V+N +      +F + +   +IGT RP
Sbjct: 862 VVIIAQRASHARVFPSCISGNRATDQNIPSGTCVENVLTSYGYDEFILSSQTPLIGTVRP 921

Query: 840 THYHVLLDEIGFSPDDLQELVHSLSYVYQRSTTAISV 876
             Y +L+++  +S ++L  L +  ++ +Q S    SV
Sbjct: 922 CKYTILVNDAKWSKNELMHLTYFRAFGHQVSYQPPSV 958


  Database: sprot
    Posted date:  Nov 25, 2004 10:54 AM
  Number of letters in database: 59,974,054
  Number of sequences in database:  164,201
  
Lambda     K      H
   0.319    0.137    0.407 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 115,402,976
Number of Sequences: 164201
Number of extensions: 5229364
Number of successful extensions: 13220
Number of sequences better than 10.0: 29
Number of HSP's better than 10.0 without gapping: 20
Number of HSP's successfully gapped in prelim test: 9
Number of HSP's that attempted gapping in prelim test: 13036
Number of HSP's gapped (non-prelim): 47
length of query: 935
length of database: 59,974,054
effective HSP length: 120
effective length of query: 815
effective length of database: 40,269,934
effective search space: 32819996210
effective search space used: 32819996210
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 71 (32.0 bits)