BLAST2 result
BLASTP 2.2.2 [Dec-14-2001]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= AC124971.1 + phase: 0
(397 letters)
Database: sprot
164,201 sequences; 59,974,054 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
P2C1_SCHPO (P40371) Protein phosphatase 2C homolog 1 (EC 3.1.3.1... 72 2e-12
P2C2_CAEEL (P49596) Probable protein phosphatase 2C T23F11.1 (EC... 68 4e-11
P2C1_YEAST (P35182) Protein phosphatase 2C homolog 1 (EC 3.1.3.1... 68 4e-11
P2C1_ARATH (P49597) Protein phosphatase 2C ABI1 (EC 3.1.3.16) (P... 68 5e-11
P2C2_ARATH (O04719) Protein phosphatase 2C ABI2 (EC 3.1.3.16) (P... 67 6e-11
P2C3_SCHPO (Q09173) Protein phosphatase 2C homolog 3 (EC 3.1.3.1... 61 4e-09
P2CB_BOVIN (O62830) Protein phosphatase 2C beta isoform (EC 3.1.... 60 1e-08
P2CA_BOVIN (O62829) Protein phosphatase 2C alpha isoform (EC 3.1... 59 2e-08
P2CB_HUMAN (O75688) Protein phosphatase 2C beta isoform (EC 3.1.... 59 3e-08
P2CA_RAT (P20650) Protein phosphatase 2C alpha isoform (EC 3.1.3... 59 3e-08
P2CA_RABIT (P35814) Protein phosphatase 2C alpha isoform (EC 3.1... 59 3e-08
P2CA_MOUSE (P49443) Protein phosphatase 2C alpha isoform (EC 3.1... 59 3e-08
P2CA_HUMAN (P35813) Protein phosphatase 2C alpha isoform (EC 3.1... 59 3e-08
FEM2_HUMAN (P49593) Ca(2+)/calmodulin-dependent protein kinase p... 58 5e-08
P2CB_MOUSE (P36993) Protein phosphatase 2C beta isoform (EC 3.1.... 57 8e-08
P2C_PARTE (P49444) Protein phosphatase 2C (EC 3.1.3.16) (PP2C) 56 1e-07
P2CB_RAT (P35815) Protein phosphatase 2C beta isoform (EC 3.1.3.... 56 1e-07
P2CG_HUMAN (O15355) Protein phosphatase 2C gamma isoform (EC 3.1... 54 7e-07
P2C4_ARATH (P49598) Protein phosphatase 2C (EC 3.1.3.16) (PP2C) 54 7e-07
P2CG_BOVIN (P79126) Protein phosphatase 2C gamma isoform (EC 3.1... 53 2e-06
>P2C1_SCHPO (P40371) Protein phosphatase 2C homolog 1 (EC 3.1.3.16)
(PP2C-1)
Length = 347
Score = 72.0 bits (175), Expect = 2e-12
Identities = 78/267 (29%), Positives = 119/267 (44%), Gaps = 38/267 (14%)
Query: 67 EFGKNSL--FVGVYDGHKGLDAARFIRVCLFPELSRLV-TENKVVSEDIMEQAVDFIEKG 123
+FG N FV VYDGH G+ A+ + + L L V E + D+M++ F+E
Sbjct: 95 DFGGNQDDGFVAVYDGHAGIQASDYCQKNLHKVLLEKVRNEPDRLVTDLMDET--FVEVN 152
Query: 124 FKEYVTNNIDDDGRVGSVGSCCLFGIIWGRTLFVANVGDSRAILGSSKGFFKRPHVVQLT 183
K + D G +V R L+ AN GD+R +L + ++L+
Sbjct: 153 SKIAKATHNDICGCTAAVAFFRYEKNRTRRVLYTANAGDARIVL------CRDGKAIRLS 206
Query: 184 VDHHVSHAAAREEIRNHITNDPFVLCKNRGSLRVKSLIEITRSIGDAYLKWSDPHPSFET 243
DH S A E R +T ++ +NR + ++ +TR++GD YLK
Sbjct: 207 YDHKGSDA---NESRR-VTQLGGLMVQNR----INGVLAVTRALGDTYLK---------- 248
Query: 244 FSRYEANVISEKPFTDRRDI-DESDKFLIFASHGFWKLMTNSEAADIVYN-NSQDGISKR 301
++S PFT I + D+F I A G W ++++ EA D V N S + R
Sbjct: 249 ------ELVSAHPFTTETRIWNGHDEFFIIACDGLWDVVSDQEAVDFVRNFVSPREAAVR 302
Query: 302 LVRAALEKAINDIITYCNLQNLKAGNG 328
LV AL++ D IT C + NL G
Sbjct: 303 LVEFALKRLSTDNIT-CIVVNLTRNPG 328
>P2C2_CAEEL (P49596) Probable protein phosphatase 2C T23F11.1 (EC
3.1.3.16) (PP2C)
Length = 356
Score = 68.2 bits (165), Expect = 4e-11
Identities = 77/274 (28%), Positives = 122/274 (44%), Gaps = 42/274 (15%)
Query: 74 FVGVYDGHKGLDAARFIRVCLFPELSRLVTENKVVSEDIMEQAVDFIEKGFKEYVTN-NI 132
F VYDGH G +++ + L + V K SE M++A IEKGF E +
Sbjct: 54 FFAVYDGHGGSKVSQYSGI----NLHKKVVAQKEFSEGNMKEA---IEKGFLELDQQMRV 106
Query: 133 DDDGRVGSVGSCCLFGIIWGRTLFVANVGDSRAILGSSKGFFKRPHVVQLTVDHHVSHAA 192
D++ + G+ + +I ++ N GDSRA+ SS RP L+ DH SH
Sbjct: 107 DEETKDDVSGTTAVVVLIKEGDVYCGNAGDSRAV--SSVVGEARP----LSFDHKPSHET 160
Query: 193 AREEIRNHITNDPFVLCKNRGSLRVKSLIEITRSIGDAYLKWSDPHPSFETFSRYEANVI 252
E R I +V RV + ++R++GD K D P+ E +VI
Sbjct: 161 ---EARRIIAAGGWVEFN-----RVNGNLALSRALGDFAFKNCDTKPAEEQIVTAFPDVI 212
Query: 253 SEKPFTDRRDIDESDKFLIFASHGFWKLMTNSEAADIVYNNSQDGISKRLVRAALEKAIN 312
++K D +F++ A G W +MTN E D V + KR ++ E
Sbjct: 213 TDKLTPDH-------EFIVLACDGIWDVMTNQEVVDFVREKLAE---KRDPQSICE---- 258
Query: 313 DIITYCNLQNLKAGNGLLGRRHYYDDVTVIVIFL 346
+++T C + + G LG D++TV+++ L
Sbjct: 259 ELLTRCLAPDCQMGG--LG----CDNMTVVLVGL 286
>P2C1_YEAST (P35182) Protein phosphatase 2C homolog 1 (EC 3.1.3.16)
(PP2C-1)
Length = 281
Score = 68.2 bits (165), Expect = 4e-11
Identities = 62/261 (23%), Positives = 110/261 (41%), Gaps = 56/261 (21%)
Query: 74 FVGVYDGHKGLDAARFIRVCLFPELSRLVTENKVVSE-----DIMEQAVDFIEKGFKEYV 128
+ V+DGH G+ A+++ L ++ +N + E D++ + I++ +
Sbjct: 53 YFAVFDGHAGIQASKWCG----KHLHTIIEQNILADETRDVRDVLNDSFLAIDEEINTKL 108
Query: 129 TNNIDDDGRV--------GSVGSCCLFGIIWGRTLFVANVGDSRAILGSSKGFFKRPHVV 180
N V SV + R L+ ANVGDSR +L F+ + +
Sbjct: 109 VGNSGCTAAVCVLRWELPDSVSDDSMDLAQHQRKLYTANVGDSRIVL------FRNGNSI 162
Query: 181 QLTVDHHVSHAAAREEIRNHITNDPFVLCKNRGSL----RVKSLIEITRSIGDAYLKWSD 236
+LT DH S + + + G L RV ++ +TRS+GD +
Sbjct: 163 RLTYDHKASDTLEMQRV------------EQAGGLIMKSRVNGMLAVTRSLGDKFFD--- 207
Query: 237 PHPSFETFSRYEANVISEKPFTDRRDIDESDKFLIFASHGFWKLMTNSEAADIVYNNSQ- 295
+++ PFT +I DKFLI A G W ++ + +A +++ + ++
Sbjct: 208 -------------SLVVGSPFTTSVEITSEDKFLILACDGLWDVIDDQDACELIKDITEP 254
Query: 296 DGISKRLVRAALEKAINDIIT 316
+ +K LVR ALE D +T
Sbjct: 255 NEAAKVLVRYALENGTTDNVT 275
>P2C1_ARATH (P49597) Protein phosphatase 2C ABI1 (EC 3.1.3.16)
(PP2C) (Abscisic acid-insensitive 1)
Length = 434
Score = 67.8 bits (164), Expect = 5e-11
Identities = 64/221 (28%), Positives = 100/221 (44%), Gaps = 36/221 (16%)
Query: 74 FVGVYDGHKGLDAARFIRVCLFPELSRLVTENKVVSEDIMEQAVDFIEKGFKEYVTNNID 133
F GVYDGH G A + R + L+ + + K + D ++EK K + +
Sbjct: 172 FFGVYDGHGGSQVANYCRERMHLALAEEIAKEKPMLCD----GDTWLEKWKKALFNSFLR 227
Query: 134 DDGRVGSV-----GSCCLFGIIWGRTLFVANVGDSRAILGSSKGFFKRPHVVQLTVDHHV 188
D + SV GS + +++ +FVAN GDSRA+L K + L+VDH
Sbjct: 228 VDSEIESVAPETVGSTSVVAVVFPSHIFVANCGDSRAVLCRGK------TALPLSVDHKP 281
Query: 189 SHAAAREEIRNHITNDPFVLCKNRGSLRVKSLIEITRSIGDAYLKWSDPHPSFETFSRYE 248
RE+ I + + G+ RV ++ ++RSIGD YLK
Sbjct: 282 D----REDEAARIEAAGGKVIQWNGA-RVFGVLAMSRSIGDRYLK--------------- 321
Query: 249 ANVISEKPFTDRRDIDESDKFLIFASHGFWKLMTNSEAADI 289
++I + T + + E D LI AS G W +MT+ EA ++
Sbjct: 322 PSIIPDPEVTAVKRVKEDD-CLILASDGVWDVMTDEEACEM 361
>P2C2_ARATH (O04719) Protein phosphatase 2C ABI2 (EC 3.1.3.16)
(PP2C) (Abscisic acid-insensitive 2)
Length = 423
Score = 67.4 bits (163), Expect = 6e-11
Identities = 66/224 (29%), Positives = 100/224 (44%), Gaps = 40/224 (17%)
Query: 74 FVGVYDGHKGLDAARFIRVCLFPELSRLVTENKVVSEDIMEQAVDFIEKGFKEYVTNN-- 131
F GVYDGH G A + R E L ++V E D ++ +K+ + N+
Sbjct: 160 FFGVYDGHGGSQVANYCR-----ERMHLALTEEIVKEKPEFCDGDTWQEKWKKALFNSFM 214
Query: 132 -IDDDGRV-----GSVGSCCLFGIIWGRTLFVANVGDSRAILGSSKGFFKRPHVVQLTVD 185
+D + +VGS + +++ +FVAN GDSRA+L K + L+VD
Sbjct: 215 RVDSEIETVAHAPETVGSTSVVAVVFPTHIFVANCGDSRAVLCRGK------TPLALSVD 268
Query: 186 HHVSHAAAREEIRNHITNDPFVLCKNRGSLRVKSLIEITRSIGDAYLKWSDPHPSFETFS 245
H R++ I + + G+ RV ++ ++RSIGD YLK
Sbjct: 269 HKPD----RDDEAARIEAAGGKVIRWNGA-RVFGVLAMSRSIGDRYLK------------ 311
Query: 246 RYEANVISEKPFTDRRDIDESDKFLIFASHGFWKLMTNSEAADI 289
+VI + T R + E D LI AS G W +MTN E D+
Sbjct: 312 ---PSVIPDPEVTSVRRVKEDD-CLILASDGLWDVMTNEEVCDL 351
>P2C3_SCHPO (Q09173) Protein phosphatase 2C homolog 3 (EC 3.1.3.16)
(PP2C-3)
Length = 414
Score = 61.2 bits (147), Expect = 4e-09
Identities = 71/298 (23%), Positives = 120/298 (39%), Gaps = 49/298 (16%)
Query: 74 FVGVYDGHKGLDAARFIRVCLFPELSRLVTENKVVSEDIMEQAVDFIEKGFKEYVTNNID 133
F VYDGH G A++ L +++ +N + V+ ++ F +D
Sbjct: 57 FFAVYDGHGGDKVAKWCG----SNLPQILEKNPDFQKG---DFVNALKSSFLNADKAILD 109
Query: 134 DDGRVGSVGSCCLFGIIW-GRTLFVANVGDSRAILGSSKGFFKRPHVVQLTVDHHVSHAA 192
DD C ++ G L+ AN GDSR +LGS KG K L+ DH S+ A
Sbjct: 110 DDQFHTDPSGCTATVVLRVGNKLYCANAGDSRTVLGS-KGIAK-----PLSADHKPSNEA 163
Query: 193 AREEIRNHITNDPFVLCKNRGSL---RVKSLIEITRSIGDAYLKWSDPHPSFETFSRYEA 249
+ I C G + RV + ++R+IGD K S+ P E
Sbjct: 164 EKARI-----------CAAGGFVDFGRVNGNLALSRAIGDFEFKNSNLEP--------EK 204
Query: 250 NVISEKPFTDRRDIDESDKFLIFASHGFWKLMTNSEAADIVYNNSQDGISKRLVRAALEK 309
+++ P +I + D+F++ A G W T+ + + V G S LEK
Sbjct: 205 QIVTALPDVVVHEITDDDEFVVLACDGIWDCKTSQQVIEFVRRGIVAGTS-------LEK 257
Query: 310 AINDIITYCNLQNLKAGNGLLGRRHYYDDVTVIVIFLNKRSDTPTTEPEFQSTTSTNE 367
+++ C + + LG D++TV ++ L + +D + + N+
Sbjct: 258 IAENLMDNCIASDTETTG--LG----CDNMTVCIVALLQENDKSAWYKKIADRVAAND 309
>P2CB_BOVIN (O62830) Protein phosphatase 2C beta isoform (EC
3.1.3.16) (PP2C-beta)
Length = 387
Score = 59.7 bits (143), Expect = 1e-08
Identities = 65/253 (25%), Positives = 102/253 (39%), Gaps = 36/253 (14%)
Query: 74 FVGVYDGHKGLDAARFIRVCLFPELS-----RLVTENKVVSEDIMEQAVDFIEKGF---K 125
F VYDGH G A + L ++ R ++ E +E + I GF
Sbjct: 55 FFAVYDGHAGSRVANYCSTHLLEHITNNEDFRAAGKSGSALEPSVENVKNGIRTGFLKID 114
Query: 126 EYVTNNIDDDGRVGSVGSCCLFGIIWGRTLFVANVGDSRAILGSSKGFFKRPHVVQLTVD 185
EY+ N D + GS + +I + ++ N GDSRA+L ++ V T D
Sbjct: 115 EYMRNFSDLRNGMDRSGSTAVGVMISPKHIYFINCGDSRAVL------YRSGQVCFSTQD 168
Query: 186 HHVSHAAAREEIRNHITNDPFVLCKNRGSLRVKSLIEITRSIGDAYLKWSDPHPSFETFS 245
H + +E I+N ++ + GSL V +R++GD K D E
Sbjct: 169 HKPCNPREKERIQN--AGGSVMIQRVNGSLAV------SRALGDYDYKCVDGKGPTE--- 217
Query: 246 RYEANVISEKPFTDRRDIDESDKFLIFASHGFWKLMTNSEAADIVYNNSQDGISKRLVRA 305
++S +P E D+F+I A G W +M+N E + V S+ V
Sbjct: 218 ----QLVSPEPEVYEILRAEEDEFIILACDGIWDVMSNEELCEFVK-------SRLEVSD 266
Query: 306 ALEKAINDIITYC 318
LE N ++ C
Sbjct: 267 DLENVCNWVVDTC 279
>P2CA_BOVIN (O62829) Protein phosphatase 2C alpha isoform (EC
3.1.3.16) (PP2C-alpha)
Length = 382
Score = 59.3 bits (142), Expect = 2e-08
Identities = 73/272 (26%), Positives = 106/272 (38%), Gaps = 45/272 (16%)
Query: 60 MEDFYQVEFGKNS-----LFVGVYDGHKGLDAARFIRVCLFPELSRLVTENKVVSEDIME 114
MED + G S F VYDGH G A++ L ++ +E
Sbjct: 36 MEDAHTAVIGLPSGLETWSFFAVYDGHAGSQVAKYCCEHLLDHITNNQDFKGSAGAPSVE 95
Query: 115 QAVDFIEKGFKEYVTNNIDDDGRVGSV--------GSCCLFGIIWGRTLFVANVGDSRAI 166
+ I GF E ID+ RV S GS + +I + + N GDSR +
Sbjct: 96 NVKNGIRTGFLE-----IDEHMRVMSEKKHGADRSGSTAVGVLISPQHTYFINCGDSRGL 150
Query: 167 LGSSKGFFKRPHVVQLTVDHHVSHAAAREEIRNHITNDPFVLCKNRGSLRVKSLIEITRS 226
L ++ V T DH S+ +E I+N ++ + GSL V +R+
Sbjct: 151 LCRNR------KVYFFTQDHKPSNPLEKERIQN--AGGSVMIQRVNGSLAV------SRA 196
Query: 227 IGDAYLKWSDPHPSFETFSRYEANVISEKPFTDRRDIDESDKFLIFASHGFWKLMTNSEA 286
+GD + H T E V E D +E D+F+I A G W +M N E
Sbjct: 197 LGD--FDYKCVHGKGPT----EQLVSPEPEVHDIERSEEDDQFIILACDGIWDVMGNEEL 250
Query: 287 ADIVYNNSQDGISKRLVRAALEKAINDIITYC 318
D V S+ V LEK N+++ C
Sbjct: 251 CDFVR-------SRLEVTDDLEKVCNEVVDTC 275
>P2CB_HUMAN (O75688) Protein phosphatase 2C beta isoform (EC
3.1.3.16) (PP2C-beta)
Length = 479
Score = 58.5 bits (140), Expect = 3e-08
Identities = 65/253 (25%), Positives = 102/253 (39%), Gaps = 36/253 (14%)
Query: 74 FVGVYDGHKGLDAARFIRVCLFPELS-----RLVTENKVVSEDIMEQAVDFIEKGF---K 125
F VYDGH G A + L ++ R ++ E +E + I GF
Sbjct: 55 FFAVYDGHAGSRVANYCSTHLLEHITTNEDFRAAGKSGSALELSVENVKNGIRTGFLKID 114
Query: 126 EYVTNNIDDDGRVGSVGSCCLFGIIWGRTLFVANVGDSRAILGSSKGFFKRPHVVQLTVD 185
EY+ N D + GS + +I + ++ N GDSRA+L ++ V T D
Sbjct: 115 EYMRNFSDLRNGMDRSGSTAVGVMISPKHIYFINCGDSRAVL------YRNGQVCFSTQD 168
Query: 186 HHVSHAAAREEIRNHITNDPFVLCKNRGSLRVKSLIEITRSIGDAYLKWSDPHPSFETFS 245
H + +E I+N ++ + GSL V +R++GD K D E
Sbjct: 169 HKPCNPREKERIQN--AGGSVMIQRVNGSLAV------SRALGDYDYKCVDGKGPTE--- 217
Query: 246 RYEANVISEKPFTDRRDIDESDKFLIFASHGFWKLMTNSEAADIVYNNSQDGISKRLVRA 305
++S +P E D+F+I A G W +M+N E + V S+ V
Sbjct: 218 ----QLVSPEPEVYEILRAEEDEFIILACDGIWDVMSNEELCEYVK-------SRLEVSD 266
Query: 306 ALEKAINDIITYC 318
LE N ++ C
Sbjct: 267 DLENVCNWVVDTC 279
>P2CA_RAT (P20650) Protein phosphatase 2C alpha isoform (EC
3.1.3.16) (PP2C-alpha) (IA) (Protein phosphatase 1A)
Length = 382
Score = 58.5 bits (140), Expect = 3e-08
Identities = 73/272 (26%), Positives = 106/272 (38%), Gaps = 45/272 (16%)
Query: 60 MEDFYQVEFGKNS-----LFVGVYDGHKGLDAARFIRVCLFPELSRLVTENKVVSEDIME 114
MED + G S F VYDGH G A++ L ++ +E
Sbjct: 36 MEDAHTAVIGLPSGLETWSFFAVYDGHAGSQVAKYCCEHLLDHITNNQDFKGSAGAPSVE 95
Query: 115 QAVDFIEKGFKEYVTNNIDDDGRVGSV--------GSCCLFGIIWGRTLFVANVGDSRAI 166
+ I GF E ID+ RV S GS + +I + + N GDSR +
Sbjct: 96 NVKNGIRTGFLE-----IDEHMRVMSEKKHGADRSGSTAVGVLISPQHTYFINCGDSRGL 150
Query: 167 LGSSKGFFKRPHVVQLTVDHHVSHAAAREEIRNHITNDPFVLCKNRGSLRVKSLIEITRS 226
L ++ V T DH S+ +E I+N ++ + GSL V +R+
Sbjct: 151 LCRNR------KVHFFTQDHKPSNPLEKERIQN--AGGSVMIQRVNGSLAV------SRA 196
Query: 227 IGDAYLKWSDPHPSFETFSRYEANVISEKPFTDRRDIDESDKFLIFASHGFWKLMTNSEA 286
+GD + H T E V E D +E D+F+I A G W +M N E
Sbjct: 197 LGD--FDYKCVHGKGPT----EQLVSPEPEVHDIERSEEDDQFIILACDGIWDVMGNEEL 250
Query: 287 ADIVYNNSQDGISKRLVRAALEKAINDIITYC 318
D V S+ V LEK N+++ C
Sbjct: 251 CDFVR-------SRLEVTDDLEKVCNEVVDTC 275
>P2CA_RABIT (P35814) Protein phosphatase 2C alpha isoform (EC
3.1.3.16) (PP2C-alpha) (IA) (Protein phosphatase 1A)
Length = 382
Score = 58.5 bits (140), Expect = 3e-08
Identities = 73/272 (26%), Positives = 106/272 (38%), Gaps = 45/272 (16%)
Query: 60 MEDFYQVEFGKNS-----LFVGVYDGHKGLDAARFIRVCLFPELSRLVTENKVVSEDIME 114
MED + G S F VYDGH G A++ L ++ +E
Sbjct: 36 MEDAHTAVIGLPSGLETWSFFAVYDGHAGSQVAKYCCEHLLDHITNNQDFKGSAGAPSVE 95
Query: 115 QAVDFIEKGFKEYVTNNIDDDGRVGSV--------GSCCLFGIIWGRTLFVANVGDSRAI 166
+ I GF E ID+ RV S GS + +I + + N GDSR +
Sbjct: 96 NVKNGIRTGFLE-----IDEHMRVMSEKKHGADRSGSTAVGVLISPQHTYFINCGDSRGL 150
Query: 167 LGSSKGFFKRPHVVQLTVDHHVSHAAAREEIRNHITNDPFVLCKNRGSLRVKSLIEITRS 226
L ++ V T DH S+ +E I+N ++ + GSL V +R+
Sbjct: 151 LCRNR------KVHFFTQDHKPSNPLEKERIQN--AGGSVMIQRVNGSLAV------SRA 196
Query: 227 IGDAYLKWSDPHPSFETFSRYEANVISEKPFTDRRDIDESDKFLIFASHGFWKLMTNSEA 286
+GD + H T E V E D +E D+F+I A G W +M N E
Sbjct: 197 LGD--FDYKCVHGKGPT----EQLVSPEPEVHDIERSEEDDQFIILACDGIWDVMGNEEL 250
Query: 287 ADIVYNNSQDGISKRLVRAALEKAINDIITYC 318
D V S+ V LEK N+++ C
Sbjct: 251 CDFVR-------SRLEVTDDLEKVCNEVVDTC 275
>P2CA_MOUSE (P49443) Protein phosphatase 2C alpha isoform (EC
3.1.3.16) (PP2C-alpha) (IA) (Protein phosphatase 1A)
Length = 382
Score = 58.5 bits (140), Expect = 3e-08
Identities = 73/272 (26%), Positives = 106/272 (38%), Gaps = 45/272 (16%)
Query: 60 MEDFYQVEFGKNS-----LFVGVYDGHKGLDAARFIRVCLFPELSRLVTENKVVSEDIME 114
MED + G S F VYDGH G A++ L ++ +E
Sbjct: 36 MEDAHTAVIGLPSGLETWSFFAVYDGHAGSQVAKYCCEHLLDHITNNQDFRGSAGAPSVE 95
Query: 115 QAVDFIEKGFKEYVTNNIDDDGRVGSV--------GSCCLFGIIWGRTLFVANVGDSRAI 166
+ I GF E ID+ RV S GS + +I + + N GDSR +
Sbjct: 96 NVKNGIRTGFLE-----IDEHMRVMSEKKHGADRSGSTAVGVLISPQHTYFINCGDSRGL 150
Query: 167 LGSSKGFFKRPHVVQLTVDHHVSHAAAREEIRNHITNDPFVLCKNRGSLRVKSLIEITRS 226
L ++ V T DH S+ +E I+N ++ + GSL V +R+
Sbjct: 151 LCRNR------KVHFFTQDHKPSNPLEKERIQN--AGGSVMIQRVNGSLAV------SRA 196
Query: 227 IGDAYLKWSDPHPSFETFSRYEANVISEKPFTDRRDIDESDKFLIFASHGFWKLMTNSEA 286
+GD + H T E V E D +E D+F+I A G W +M N E
Sbjct: 197 LGD--FDYKCVHGKGPT----EQLVSPEPEVHDIERSEEDDQFIILACDGIWDVMGNEEL 250
Query: 287 ADIVYNNSQDGISKRLVRAALEKAINDIITYC 318
D V S+ V LEK N+++ C
Sbjct: 251 CDFVR-------SRLEVTDDLEKVCNEVVDTC 275
>P2CA_HUMAN (P35813) Protein phosphatase 2C alpha isoform (EC
3.1.3.16) (PP2C-alpha) (IA) (Protein phosphatase 1A)
Length = 382
Score = 58.5 bits (140), Expect = 3e-08
Identities = 73/272 (26%), Positives = 106/272 (38%), Gaps = 45/272 (16%)
Query: 60 MEDFYQVEFGKNS-----LFVGVYDGHKGLDAARFIRVCLFPELSRLVTENKVVSEDIME 114
MED + G S F VYDGH G A++ L ++ +E
Sbjct: 36 MEDAHTAVIGLPSGLESWSFFAVYDGHAGSQVAKYCCEHLLDHITNNQDFKGSAGAPSVE 95
Query: 115 QAVDFIEKGFKEYVTNNIDDDGRVGSV--------GSCCLFGIIWGRTLFVANVGDSRAI 166
+ I GF E ID+ RV S GS + +I + + N GDSR +
Sbjct: 96 NVKNGIRTGFLE-----IDEHMRVMSEKKHGADRSGSTAVGVLISPQHTYFINCGDSRGL 150
Query: 167 LGSSKGFFKRPHVVQLTVDHHVSHAAAREEIRNHITNDPFVLCKNRGSLRVKSLIEITRS 226
L ++ V T DH S+ +E I+N ++ + GSL V +R+
Sbjct: 151 LCRNR------KVHFFTQDHKPSNPLEKERIQN--AGGSVMIQRVNGSLAV------SRA 196
Query: 227 IGDAYLKWSDPHPSFETFSRYEANVISEKPFTDRRDIDESDKFLIFASHGFWKLMTNSEA 286
+GD + H T E V E D +E D+F+I A G W +M N E
Sbjct: 197 LGD--FDYKCVHGKGPT----EQLVSPEPEVHDIERSEEDDQFIILACDGIWDVMGNEEL 250
Query: 287 ADIVYNNSQDGISKRLVRAALEKAINDIITYC 318
D V S+ V LEK N+++ C
Sbjct: 251 CDFVR-------SRLEVTDDLEKVCNEVVDTC 275
>FEM2_HUMAN (P49593) Ca(2+)/calmodulin-dependent protein kinase
phosphatase (EC 3.1.3.16) (CaM-kinase phosphatase)
(CaMKPase) (Partner of PIX 2) (hFEM-2) (Protein
phosphatase 1F)
Length = 454
Score = 57.8 bits (138), Expect = 5e-08
Identities = 75/285 (26%), Positives = 123/285 (42%), Gaps = 54/285 (18%)
Query: 42 RKENDYHCSIATSQSNTVMEDFYQVEFGKNSLFVGVYDGHKGLDAARFIRVCLFPELSR- 100
RK D H S+ + + + N + V+DGH G+DAAR+ V + +R
Sbjct: 167 RKMEDRHVSLPS------FNQLFGLSDPVNRAYFAVFDGHGGVDAARYAAVHVHTNAARQ 220
Query: 101 --LVTENK-VVSEDIMEQAVDFIEKGFKEYVTNNIDDDGRVGSVGSCCLFGIIWGRTLFV 157
L T+ + + E F+ K +E + + G+ G C L I G TL V
Sbjct: 221 PELPTDPEGALREAFRRTDQMFLRKAKRERLQS--------GTTGVCAL---IAGATLHV 269
Query: 158 ANVGDSRAILGSSKGFFKRPHVVQLTVDHHVSHAAAREEIRNHITNDPFVLCKNRGSLRV 217
A +GDS+ IL ++ VV+L H + I FV + RV
Sbjct: 270 AWLGDSQVIL------VQQGQVVKLMEPHRPERQDEKARIE---ALGGFV--SHMDCWRV 318
Query: 218 KSLIEITRSIGDAYLKWSDPHPSFETFSRYEANVISEKPFTDRRDIDESDKFLIFASHGF 277
+ ++R+IGD + K P+ S EA+ S R + S+ +L+ A GF
Sbjct: 319 NGTLAVSRAIGDVFQK---PYVS------GEADAAS-------RALTGSEDYLLLACDGF 362
Query: 278 WKLMTNSEAADIVYNN--SQDG----ISKRLVRAALEKAINDIIT 316
+ ++ + E +V ++ Q G +++ LV AA E+ +D IT
Sbjct: 363 FDVVPHQEVVGLVQSHLTRQQGSGLRVAEELVAAARERGSHDNIT 407
>P2CB_MOUSE (P36993) Protein phosphatase 2C beta isoform (EC
3.1.3.16) (PP2C-beta) (IA) (Protein phosphatase 1B)
Length = 390
Score = 57.0 bits (136), Expect = 8e-08
Identities = 68/272 (25%), Positives = 105/272 (38%), Gaps = 41/272 (15%)
Query: 60 MEDFYQVEFG-----KNSLFVGVYDGHKGLDAARFIRVCLFPELS-----RLVTENKVVS 109
MED + G N F VYDGH G A + L ++ R ++
Sbjct: 36 MEDAHTAVVGIPHGLDNWSFFAVYDGHAGSRVANYCSTHLLEHITTNEDFRAADKSGSAL 95
Query: 110 EDIMEQAVDFIEKGF---KEYVTNNIDDDGRVGSVGSCCLFGIIWGRTLFVANVGDSRAI 166
E +E I GF EY+ N D + GS + ++ ++ N GDSRA+
Sbjct: 96 EPSVESVKTGIRTGFLKIDEYMRNFSDLRNGMDRSGSTAVGVMVSPTHMYFINCGDSRAV 155
Query: 167 LGSSKGFFKRPHVVQLTVDHHVSHAAAREEIRNHITNDPFVLCKNRGSLRVKSLIEITRS 226
L + V T DH + +E I+N ++ + GSL V +R+
Sbjct: 156 L------CRNGQVCFSTQDHKPCNPVEKERIQN--AGGSVMIQRVNGSLAV------SRA 201
Query: 227 IGDAYLKWSDPHPSFETFSRYEANVISEKPFTDRRDIDESDKFLIFASHGFWKLMTNSEA 286
+GD K D E ++S +P E D+F++ A G W +M+N E
Sbjct: 202 LGDYDYKCVDGKGPTE-------QLVSPEPEVYEIVRAEEDEFVVLACDGIWDVMSNEEL 254
Query: 287 ADIVYNNSQDGISKRLVRAALEKAINDIITYC 318
+ V S+ V LE N ++ C
Sbjct: 255 CEFVK-------SRLEVSDDLENVCNWVVDTC 279
>P2C_PARTE (P49444) Protein phosphatase 2C (EC 3.1.3.16) (PP2C)
Length = 300
Score = 56.2 bits (134), Expect = 1e-07
Identities = 66/286 (23%), Positives = 116/286 (40%), Gaps = 52/286 (18%)
Query: 76 GVYDGHKGLDAARFIRVCLFPELSRLVTENKVVSEDIMEQAVD--FI-----------EK 122
GV+DGH G + A+F+ EL + NK E E+A+ F+ +K
Sbjct: 54 GVFDGHGGREVAQFVEKHFVDELLK----NKNFKEQKFEEALKETFLKMDELLLTPEGQK 109
Query: 123 GFKEYVTNNIDDDGRVGSVGSCCLFGIIWGRTLFVANVGDSRAILGSSKGFFKRPHVVQL 182
+Y + D+ G +I+ TL+VAN GDSR++L + +
Sbjct: 110 ELNQYKATDTDES----YAGCTANVALIYKNTLYVANAGDSRSVLCRNNTNH------DM 159
Query: 183 TVDHHVSHAAAREEIRNHITNDPFVLCKNRGSLRVKSLIEITRSIGDAYLKWSDPHPSFE 242
+VDH + + I FV RV + ++R++GD K + S E
Sbjct: 160 SVDHKPDNPEEKSRIER---AGGFV-----SDGRVNGNLNLSRALGDLEYKRDNKLRSNE 211
Query: 243 TFSRYEANVISEKPFTDRRDIDESDKFLIFASHGFWKLMTNSEAADIVYNNSQDGISKRL 302
+I P + ++ DKF++ G ++ + + E V NS G ++
Sbjct: 212 -------QLIIALPDVKKTELTPQDKFILMGCDGVFETLNHQELLKQV--NSTIG-QAQV 261
Query: 303 VRAALEKAINDIITYCNLQNLKAGNGLLGRRHYYDDVTVIVIFLNK 348
L+KA D++ + G G D++T I+++L +
Sbjct: 262 TEELLKKAAEDLLDQLLAPDTSQGTGC-------DNMTTILVYLRR 300
>P2CB_RAT (P35815) Protein phosphatase 2C beta isoform (EC 3.1.3.16)
(PP2C-beta) (IA) (Protein phosphatase 1B)
Length = 390
Score = 56.2 bits (134), Expect = 1e-07
Identities = 64/253 (25%), Positives = 99/253 (38%), Gaps = 36/253 (14%)
Query: 74 FVGVYDGHKGLDAARFIRVCLFPELS-----RLVTENKVVSEDIMEQAVDFIEKGF---K 125
F VYDGH G A + L ++ R ++ E +E I GF
Sbjct: 55 FFAVYDGHAGSRVANYCSTHLLEHITTNEDFRAADKSGFALEPSVENVKTGIRTGFLKID 114
Query: 126 EYVTNNIDDDGRVGSVGSCCLFGIIWGRTLFVANVGDSRAILGSSKGFFKRPHVVQLTVD 185
EY+ N D + GS + +I ++ N GDSRA+L + V T D
Sbjct: 115 EYMRNFSDLRNGMDRSGSTAVGVMISPTHIYFINCGDSRAVL------CRNGQVCFSTQD 168
Query: 186 HHVSHAAAREEIRNHITNDPFVLCKNRGSLRVKSLIEITRSIGDAYLKWSDPHPSFETFS 245
H + +E I+N ++ + GSL V +R++GD K D E
Sbjct: 169 HKPCNPMEKERIQN--AGGSVMIQRVNGSLAV------SRALGDYDYKCVDGKGPTE--- 217
Query: 246 RYEANVISEKPFTDRRDIDESDKFLIFASHGFWKLMTNSEAADIVYNNSQDGISKRLVRA 305
++S +P E D+F++ A G W +M+N E + V S+ V
Sbjct: 218 ----QLVSPEPEVYEILRAEEDEFVVLACDGIWDVMSNEELCEFVN-------SRLEVSD 266
Query: 306 ALEKAINDIITYC 318
LE N ++ C
Sbjct: 267 DLENVCNWVVDTC 279
>P2CG_HUMAN (O15355) Protein phosphatase 2C gamma isoform (EC
3.1.3.16) (PP2C-gamma) (Protein phosphatase
magnesium-dependent 1 gamma) (Protein phosphatase 1C)
Length = 546
Score = 53.9 bits (128), Expect = 7e-07
Identities = 58/253 (22%), Positives = 106/253 (40%), Gaps = 35/253 (13%)
Query: 110 EDIMEQAVDFIEKGFKEYVTNNIDDDGRVGS-VGSCCLFGIIWGRTLFVANVGDSRAILG 168
ED E+A + E+ +E + ++ GS G+ + +I G+ L VAN GDSR ++
Sbjct: 295 EDDTEEAEEDDEEEEEEMMVPGMEGKEEPGSDSGTTAVVALIRGKQLIVANAGDSRCVVS 354
Query: 169 SSKGFFKRPHVVQLTVDHHVSHAAAREEIRN---HITNDPFVLCKNRGSLRVKSLIEITR 225
+ + ++ DH I+N +T D RV + ++R
Sbjct: 355 EAG------KALDMSYDHKPEDEVELARIKNAGGKVTMDG----------RVNGGLNLSR 398
Query: 226 SIGDAYLKWSDPHPSFETFSRYEANVISEKPFTDRRDIDESDKFLIFASHGFWKLMTNSE 285
+IGD + K + P E +IS P + + +F++ A G W +M++ E
Sbjct: 399 AIGDHFYKRNKNLPP-------EEQMISALPDIKVLTLTDDHEFMVIACDGIWNVMSSQE 451
Query: 286 AADIVYNNSQDGISKRLVRAALEKAINDIITYCNLQNLKAGNGLLGRRHYYDDVTVIVIF 345
D + + +R L + +++ C L +G+G D++T I+I
Sbjct: 452 VVDFIQSKISQRDENGELR-LLSSIVEELLDQC-LAPDTSGDGT-----GCDNMTCIIIC 504
Query: 346 LNKRSDTPTTEPE 358
R +T +PE
Sbjct: 505 FKPR-NTAELQPE 516
>P2C4_ARATH (P49598) Protein phosphatase 2C (EC 3.1.3.16) (PP2C)
Length = 399
Score = 53.9 bits (128), Expect = 7e-07
Identities = 75/297 (25%), Positives = 117/297 (39%), Gaps = 54/297 (18%)
Query: 70 KNSLFVGVYDGHKGLDAARFIRVCLFPELSRLV--------TENKVVS-----EDIMEQA 116
+N F GV+DGH A R L + + V TE V S +++ ++
Sbjct: 133 ENHHFYGVFDGHGCSHVAEKCRERLHDIVKKEVEVMASDEWTETMVKSFQKMDKEVSQRE 192
Query: 117 VDFIEKGFKEYVTNNID---DDGRVGSVGSCCLFGIIWGRTLFVANVGDSRAILGSSKGF 173
+ + G + N+ + +VGS + ++ + V+N GDSRA+L
Sbjct: 193 CNLVVNGATRSMKNSCRCELQSPQCDAVGSTAVVSVVTPEKIIVSNCGDSRAVL------ 246
Query: 174 FKRPHVVQLTVDHHVSHAAAREEIRNHITNDPFVLCKNRGSLRVKSLIEITRSIGDAYLK 233
+ + L+VDH E IR + RV ++ ++R+IGD YLK
Sbjct: 247 CRNGVAIPLSVDHKPDR--PDELIRIQQAGGRVIYW---DGARVLGVLAMSRAIGDNYLK 301
Query: 234 -WSDPHPSFETFSRYEANVISEKPFTDRRDIDESDKFLIFASHGFWKLMTNSEAADIVYN 292
+ P P E TDR D DE LI AS G W D+V N
Sbjct: 302 PYVIPDP--------------EVTVTDRTDEDEC---LILASDGLW---------DVVPN 335
Query: 293 NSQDGISKRLVRAALEKAINDIITYCNLQNLKAGNGLLGRRHYYDDVTVIVIFLNKR 349
+ G+++ +R A +D L R D+V+V+V+ L KR
Sbjct: 336 ETACGVARMCLRGAGAGDDSDAAHNACSDAALLLTKLALARQSSDNVSVVVVDLRKR 392
>P2CG_BOVIN (P79126) Protein phosphatase 2C gamma isoform (EC
3.1.3.16) (PP2C-gamma) (Protein phosphatase
magnesium-dependent 1 gamma) (Protein phosphatase 1B)
(Magnesium-dependent calcium inhibitable phosphatase)
(MCPP)
Length = 543
Score = 52.8 bits (125), Expect = 2e-06
Identities = 62/253 (24%), Positives = 107/253 (41%), Gaps = 37/253 (14%)
Query: 110 EDIMEQAVDFIEKGFKEYVTNNIDDDGRVGS-VGSCCLFGIIWGRTLFVANVGDSRAILG 168
ED E+A + E+ +E + ++ GS G+ + +I G+ L VAN GDSR ++
Sbjct: 295 EDDTEEAEEDDEE--EEMMVPGMEGKEEPGSDSGTTAVVALIRGKQLIVANAGDSRCVVS 352
Query: 169 SSKGFFKRPHVVQLTVDHHVSHAAAREEIRN---HITNDPFVLCKNRGSLRVKSLIEITR 225
+ + ++ DH I+N +T D RV + ++R
Sbjct: 353 EAG------KALDMSYDHKPEDEVELARIKNAGGKVTMDG----------RVNGGLNLSR 396
Query: 226 SIGDAYLKWSDPHPSFETFSRYEANVISEKPFTDRRDIDESDKFLIFASHGFWKLMTNSE 285
+IGD + K + P E +IS P + + +F++ A G W +M++ E
Sbjct: 397 AIGDHFYKRNKNLPP-------EEQMISALPDIKVLTLTDDHEFMVIACDGIWNVMSSQE 449
Query: 286 AADIVYNNSQDGISKRLVRAALEKAINDIITYCNLQNLKAGNGLLGRRHYYDDVTVIVIF 345
D + Q IS+R L + ++ I+ Y Q L G D++T I+I
Sbjct: 450 VIDFI----QSKISQRDENGEL-RLLSSIVEYLLDQCLAPDTS--GDGTGCDNMTCIIIC 502
Query: 346 LNKRSDTPTTEPE 358
R +T +PE
Sbjct: 503 FKPR-NTAAPQPE 514
Database: sprot
Posted date: Nov 25, 2004 10:54 AM
Number of letters in database: 59,974,054
Number of sequences in database: 164,201
Lambda K H
0.320 0.137 0.404
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 47,225,237
Number of Sequences: 164201
Number of extensions: 2043629
Number of successful extensions: 11722
Number of sequences better than 10.0: 72
Number of HSP's better than 10.0 without gapping: 26
Number of HSP's successfully gapped in prelim test: 46
Number of HSP's that attempted gapping in prelim test: 11458
Number of HSP's gapped (non-prelim): 162
length of query: 397
length of database: 59,974,054
effective HSP length: 112
effective length of query: 285
effective length of database: 41,583,542
effective search space: 11851309470
effective search space used: 11851309470
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 67 (30.4 bits)
Medicago: description of AC124971.1