BLAST2 result
BLASTP 2.2.2 [Dec-14-2001]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= AC123593.9 + phase: 0 /pseudo
(409 letters)
Database: sprot
164,201 sequences; 59,974,054 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
NTPA_PEA (P52914) Nucleoside-triphosphatase (EC 3.6.1.15) (Nucle... 717 0.0
APY_SOLTU (P80595) Apyrase precursor (EC 3.6.1.5) (ATP-diphospha... 416 e-116
GDA1_SCHPO (Q9UT35) Guanosine-diphosphatase (EC 3.6.1.42) (GDPase) 176 1e-43
ENP5_HUMAN (O75356) Ectonucleoside triphosphate diphosphohydrola... 161 2e-39
ENP5_MESAU (Q9QYC8) Ectonucleoside triphosphate diphosphohydrola... 157 5e-38
ENP5_MOUSE (Q9WUZ9) Ectonucleoside triphosphate diphosphohydrola... 155 1e-37
ENP6_HUMAN (O75354) Ectonucleoside triphosphate diphosphohydrola... 155 2e-37
GDA1_KLULA (Q9HEM6) Guanosine-diphosphatase (EC 3.6.1.42) (GDPase) 151 3e-36
ENP6_RAT (Q9ER31) Ectonucleoside triphosphate diphosphohydrolase... 151 3e-36
GDA1_ASPFU (Q8TGG8) Probable guanosine-diphosphatase (EC 3.6.1.4... 145 2e-34
GDA1_YEAST (P32621) Guanosine-diphosphatase (EC 3.6.1.42) (GDPase) 143 9e-34
GDA1_CANAL (Q8TGH6) Guanosine-diphosphatase (EC 3.6.1.42) (GDPase) 139 1e-32
ENP1_BOVIN (O18956) Ectonucleoside triphosphate diphosphohydrola... 134 4e-31
ENP1_HUMAN (P49961) Ectonucleoside triphosphate diphosphohydrola... 133 7e-31
ENP1_MOUSE (P55772) Ectonucleoside triphosphate diphosphohydrola... 128 2e-29
YND1_YEAST (P40009) Golgi apyrase (EC 3.6.1.5) (ATP-diphosphatas... 126 9e-29
ENP2_CHICK (P79784) Ectonucleoside triphosphate diphosphohydrola... 125 1e-28
ENP1_RAT (P97687) Ectonucleoside triphosphate diphosphohydrolase... 124 3e-28
MI23_CAEEL (Q21815) Nucleoside-diphosphatase mig-23 (EC 3.6.1.-)... 119 1e-26
ENP3_HUMAN (O75355) Ectonucleoside triphosphate diphosphohydrola... 118 3e-26
>NTPA_PEA (P52914) Nucleoside-triphosphatase (EC 3.6.1.15)
(Nucleoside triphosphate phosphohydrolase) (NTPase)
(Apyrase)
Length = 455
Score = 717 bits (1851), Expect = 0.0
Identities = 357/409 (87%), Positives = 379/409 (92%), Gaps = 1/409 (0%)
Query: 1 MEFLITLITTVLLLLMPAITSSQYLGNNLLTNRKIFQKQETISSYAVVFDAGSTGSRIHV 60
ME LI LIT LL MPAITSSQYLGNNLLT+RKIF KQE ISSYAVVFDAGSTGSRIHV
Sbjct: 1 MELLIKLIT-FLLFSMPAITSSQYLGNNLLTSRKIFLKQEEISSYAVVFDAGSTGSRIHV 59
Query: 61 YHFDQNLDLLHIGKDVEFFNKITPGLSSYANDPEQAAKSLIPLLQQAENVVPIDLHHKTP 120
YHF+QNLDLLHIGK VE++NKITPGLSSYAN+PEQAAKSLIPLL+QAE+VVP DL KTP
Sbjct: 60 YHFNQNLDLLHIGKGVEYYNKITPGLSSYANNPEQAAKSLIPLLEQAEDVVPDDLQPKTP 119
Query: 121 IRLGATAGLRLLNGDASEKILQAVRDMFSNRSTFNVQPDAVSIIDGTQEGSYLWVTVNYA 180
+RLGATAGLRLLNGDASEKILQ+VRDM SNRSTFNVQPDAVSIIDGTQEGSYLWVTVNYA
Sbjct: 120 VRLGATAGLRLLNGDASEKILQSVRDMLSNRSTFNVQPDAVSIIDGTQEGSYLWVTVNYA 179
Query: 181 LGNLGKKYTKTVGVMDLGGGSVQMAYAVSKKTAKNAPKVADGVDPYIKKLVLKGKPYDLY 240
LGNLGKKYTKTVGV+DLGGGSVQMAYAVSKKTAKNAPKVADG DPYIKK+VLKG PYDLY
Sbjct: 180 LGNLGKKYTKTVGVIDLGGGSVQMAYAVSKKTAKNAPKVADGDDPYIKKVVLKGIPYDLY 239
Query: 241 VHSYLHFGREASRAEIMKVTRSSPNPCLLAGFDGTYTYAGEEFKAKAPASGANFNGCKKI 300
VHSYLHFGREASRAEI+K+T SPNPCLLAGF+G YTY+GEEFKA A SGANFN CK
Sbjct: 240 VHSYLHFGREASRAEILKLTPRSPNPCLLAGFNGIYTYSGEEFKATAYTSGANFNKCKNT 299
Query: 301 IRKALKLNYPCPYQNCTFGGIWNGGGGNGQKHLFASSSFFYLPEDVGMVDPKTPNFKIRP 360
IRKALKLNYPCPYQNCTFGGIWNGGGGNGQK+LFASSSFFYLPED GMVD TPNF +RP
Sbjct: 300 IRKALKLNYPCPYQNCTFGGIWNGGGGNGQKNLFASSSFFYLPEDTGMVDASTPNFILRP 359
Query: 361 VDLVSEAKKACALNFEDAKSTYPFLAKKNIASYVCMDLIYQYVLLVDGF 409
VD+ ++AK+ACALNFEDAKSTYPFL KKN+ASYVCMDLIYQYVLLVDGF
Sbjct: 360 VDIETKAKEACALNFEDAKSTYPFLDKKNVASYVCMDLIYQYVLLVDGF 408
>APY_SOLTU (P80595) Apyrase precursor (EC 3.6.1.5)
(ATP-diphosphatase) (Adenosine diphosphatase) (ADPase)
(ATP-diphosphohydrolase)
Length = 454
Score = 416 bits (1069), Expect = e-116
Identities = 205/402 (50%), Positives = 276/402 (67%), Gaps = 4/402 (0%)
Query: 8 ITTVLLLLMPAITSSQYLGNNLLTNRKIFQKQETISSYAVVFDAGSTGSRIHVYHFDQNL 67
I + L++P S+ + + R + + YAV+FDAGSTGSR+HV+ FD+ L
Sbjct: 11 IILAIFLVLPLSLLSKNVNAQIPLRRHLLSHES--EHYAVIFDAGSTGSRVHVFRFDEKL 68
Query: 68 DLLHIGKDVEFFNKITPGLSSYANDPEQAAKSLIPLLQQAENVVPIDLHHKTPIRLGATA 127
LL IG ++E+F PGLSSYA DP+ AA SL PLL AE VVP +L +TP+ LGATA
Sbjct: 69 GLLPIGNNIEYFMATEPGLSSYAEDPKAAANSLEPLLDGAEGVVPQELQSETPLELGATA 128
Query: 128 GLRLLNGDASEKILQAVRDMFSNRSTFNVQPDAVSIIDGTQEGSYLWVTVNYALGNLGKK 187
GLR+L GDA+EKILQAVR++ N+STF+ + V+I+DGTQEGSY+W +NY LGNLGK
Sbjct: 129 GLRMLKGDAAEKILQAVRNLVKNQSTFHSKDQWVTILDGTQEGSYMWAAINYLLGNLGKD 188
Query: 188 YTKTVGVMDLGGGSVQMAYAVSKKTAKNAPKVADGVDPYIKKLVLKGKPYDLYVHSYLHF 247
Y T +DLGGGSVQMAYA+S + AP+ DG +PY+++ L K Y+LYVHSYL++
Sbjct: 189 YKSTTATIDLGGGSVQMAYAISNEQFAKAPQNEDG-EPYVQQKHLMSKDYNLYVHSYLNY 247
Query: 248 GREASRAEIMKVTRSSPNPCLLAGFDGTYTYAGEEFKAKAPASGANFNGCKKIIRKALKL 307
G+ A RAEI K +R+ NPC L G DG Y+Y G ++K KAP G+++ C+++ R ALK+
Sbjct: 248 GQLAGRAEIFKASRNESNPCALEGCDGYYSYGGVDYKVKAPKKGSSWKRCRRLTRHALKI 307
Query: 308 NYPCPYQNCTFGGIWNGGGGNGQKHLFASSSFFYLPEDVGMVDPKTPNFKIRPVDLVSEA 367
N C + CTF G+WNGGGG+GQK++ ASS F+ + VG+VD K P+ +P+ ++ A
Sbjct: 308 NAKCNIEECTFNGVWNGGGGDGQKNIHASSFFYDIGAQVGIVDTKFPSALAKPIQYLNAA 367
Query: 368 KKACALNFEDAKSTYPFLAKKNIASYVCMDLIYQYVLLVDGF 409
K AC N D KS +P +NI Y+CMDLIY+Y LLVDGF
Sbjct: 368 KVACQTNVADIKSIFPKTQDRNI-PYLCMDLIYEYTLLVDGF 408
>GDA1_SCHPO (Q9UT35) Guanosine-diphosphatase (EC 3.6.1.42) (GDPase)
Length = 556
Score = 176 bits (446), Expect = 1e-43
Identities = 133/403 (33%), Positives = 194/403 (48%), Gaps = 45/403 (11%)
Query: 36 FQKQETISSYAVVFDAGSTGSRIHVYHFDQNLDLLHIGKDVEFFNKITPGLSSYANDPEQ 95
+ + + Y ++ DAGSTGSR+HVY F+ + + EFF I PGLSS+A DPE
Sbjct: 125 YDNSKPVRQYVLMIDAGSTGSRVHVYQFNNCNPSPKL--EEEFFKMIEPGLSSFAGDPEG 182
Query: 96 AAKSLIPLLQQAENVVPIDLHHKTPIRLGATAGLRLLNGDASEKILQAVRDMFSNRSTFN 155
AA SL PLL A VP + +PI + ATAGLRL ++ IL++VR N F
Sbjct: 183 AAASLDPLLDYAMENVPEEYRRCSPIAVKATAGLRLTGESEAKAILKSVRQHLENDYPFP 242
Query: 156 VQPDAVSIIDGTQEGSYLWVTVNYALGNLGKKYT-KTVGVMDLGGGSVQMAYAVSKKTAK 214
+ D VSI++G+ EG Y W+T+NY LG LG K T TV VMDLGG S Q+ + + A
Sbjct: 243 IVKDGVSILEGSMEGIYAWITINYLLGTLGGKATHSTVAVMDLGGASTQLVF--EPRFAS 300
Query: 215 NAPKVADGVDPYIKKLVLKGKPYDLYVHSYLHFGREASR-----------------AEIM 257
+ + DG Y+ L G+ Y+LY HS+L +G + +R E++
Sbjct: 301 DGESLVDGDHKYV--LDYNGEQYELYQHSHLGYGLKEARKLIHKFVLNNAEALKESLELL 358
Query: 258 KVTRSSPNPCLLAGFDGTYTYAGEEFKAKAPASGANFNG---------CKKIIRKALKLN 308
+ S +PCL T+ +K+ AS F G C+ I KAL +
Sbjct: 359 GDSTSIIHPCLHLNASLTHP------DSKSEASEVVFVGPSLAHLSLQCRGIAEKALYKD 412
Query: 309 YPCPYQNCTFGGIWNGGGGN--GQKHLFASSSFFYLPEDVGMVDPKTPNFKIRPVDLVSE 366
CP + C+F G+ ++ S F+ +GM P T F I + ++
Sbjct: 413 KNCPVRPCSFNGVHQPKFTETFTDSPIYLISYFYDRMISLGM--PST--FTIEDMKYLAN 468
Query: 367 AKKACALNFEDAKSTYPFLAKKNIASYVCMDLIYQYVLLVDGF 409
+ + ++DA S L + C+DL Y LL G+
Sbjct: 469 SVCSGPTYWQDAFSLTDALKELKEEPEWCLDLNYMISLLSVGY 511
>ENP5_HUMAN (O75356) Ectonucleoside triphosphate diphosphohydrolase
5 precursor (EC 3.6.1.6) (NTPDase5) (Nucleoside
diphosphatase) (CD39 antigen-like 4) (ER-UDPase)
Length = 428
Score = 161 bits (408), Expect = 2e-39
Identities = 119/376 (31%), Positives = 185/376 (48%), Gaps = 44/376 (11%)
Query: 45 YAVVFDAGSTGSRIHVYHFDQNLDLLHIGKDVEFFNKITPGLSSYANDPEQAAKSLIPLL 104
Y ++FDAGSTG+RIHVY F Q + + E F+ + PGLS++ + P+Q A+++ LL
Sbjct: 49 YGIMFDAGSTGTRIHVYTFVQKMPGQLPILEGEVFDSVKPGLSAFVDQPKQGAETVQGLL 108
Query: 105 QQAENVVPIDLHHKTPIRLGATAGLRLLNGDASEKILQAVRDMFSNRSTFNVQPDAVSII 164
+ A++ +P KTP+ L ATAGLRLL ++ +L V+++F +S F V +VSI+
Sbjct: 109 EVAKDSIPRSHWKKTPVVLKATAGLRLLPEHKAKALLFEVKEIF-RKSPFLVPKGSVSIM 167
Query: 165 DGTQEGSYLWVTVNYALGNLGKKYTKTVGVMDLGGGSVQMAYAVS-KKTAKNAPKVADGV 223
DG+ EG WVTVN+ G L +TVG +DLGG S Q+ + +KT + P+
Sbjct: 168 DGSDEGILAWVTVNFLTGQLHGHRQETVGTLDLGGASTQITFLPQFEKTLEQTPR----- 222
Query: 224 DPYIKKLVLKGKPYDLYVHSYLHFGREASRAEIMKVTRSS-------PNPCLLAGFDGTY 276
Y+ + Y LY HSYL FG +A+R + + + CL + +
Sbjct: 223 -GYLTSFEMFNSTYKLYTHSYLGFGLKAARLATLGALETEGTDGHTFRSACLPRWLEAEW 281
Query: 277 TYAGEEFKAKAPASG-ANFNGCKKIIRKAL--KLNYPCPYQNCTFGGIWNGGGGNGQKHL 333
+ G +++ G F C + + + KL+ P Q +F
Sbjct: 282 IFGGVKYQYGGNQEGEVGFEPCYAEVLRVVRGKLHQPEEVQRGSF--------------- 326
Query: 334 FASSSFFYLPEDVGMVDPKTPNFKIRPVDLVSEAKKACALNFEDAKSTYPFLAKKNIASY 393
+A S ++ D M+D + ++ D +A++ C N E+ S PFL
Sbjct: 327 YAFSYYYDRAVDTDMIDYEKGGI-LKVEDFERKAREVCD-NLENFTSGSPFL-------- 376
Query: 394 VCMDLIYQYVLLVDGF 409
CMDL Y LL DGF
Sbjct: 377 -CMDLSYITALLKDGF 391
>ENP5_MESAU (Q9QYC8) Ectonucleoside triphosphate diphosphohydrolase
5 precursor (EC 3.6.1.6) (NTPDase5) (Nucleoside
diphosphatase) (CD39 antigen-like 4) (ER-UDPase)
(Proto-oncogene cph)
Length = 469
Score = 157 bits (397), Expect = 5e-38
Identities = 116/376 (30%), Positives = 182/376 (47%), Gaps = 44/376 (11%)
Query: 45 YAVVFDAGSTGSRIHVYHFDQNLDLLHIGKDVEFFNKITPGLSSYANDPEQAAKSLIPLL 104
Y ++FDAGSTG+RIHVY F Q + E F+ + PGLS++A+ P+Q A+++ LL
Sbjct: 49 YGIMFDAGSTGTRIHVYTFVQKAAGQLPFLEGEIFDSVKPGLSAFADQPKQGAQTVHALL 108
Query: 105 QQAENVVPIDLHHKTPIRLGATAGLRLLNGDASEKILQAVRDMFSNRSTFNVQPDAVSII 164
+ A++ +P +TP+ L ATAGLRLL ++ +L V ++F S F V D+VSI+
Sbjct: 109 EVAKDSIPRSHWKRTPVVLKATAGLRLLPEQKAQALLLEVEEIF-KMSPFLVPDDSVSIM 167
Query: 165 DGTQEGSYLWVTVNYALGNLGKKYTKTVGVMDLGGGSVQMAYAVS-KKTAKNAPKVADGV 223
DG+ EG WVTVN+ G L +T+G +DLGG S Q+ + KT + P+
Sbjct: 168 DGSYEGILAWVTVNFLTGQLHGHSQETMGTLDLGGASTQITFLPQFSKTLEQTPR----- 222
Query: 224 DPYIKKLVLKGKPYDLYVHSYLHFGREASRAEIMKVTRSS-------PNPCLLAGFDGTY 276
Y+ + + LY HSYL FG +A+R + + + CL + +
Sbjct: 223 -DYLTSFEMFNSTFKLYTHSYLGFGLKAARLATLGALETEGTDGHTFRSACLPRWLEAEW 281
Query: 277 TYAGEEFKAKAPASG-ANFNGCKKIIRKAL--KLNYPCPYQNCTFGGIWNGGGGNGQKHL 333
+ G +++ G F C + + + KL+ P + +F
Sbjct: 282 IFGGVKYQYGGNQEGEMGFEPCYAEVLRVVQGKLHQPEEIRGSSF--------------- 326
Query: 334 FASSSFFYLPEDVGMVDPKTPNFKIRPVDLVSEAKKACALNFEDAKSTYPFLAKKNIASY 393
+A S ++ D ++D + ++ D +A++ C N E S PFL
Sbjct: 327 YAFSYYYDRAADTHLIDYEKGGV-LKVEDFERKAREVCD-NLESFTSGSPFL-------- 376
Query: 394 VCMDLIYQYVLLVDGF 409
CMDL Y LL DGF
Sbjct: 377 -CMDLSYITALLKDGF 391
>ENP5_MOUSE (Q9WUZ9) Ectonucleoside triphosphate diphosphohydrolase
5 precursor (EC 3.6.1.6) (NTPDase5) (Nucleoside
diphosphatase) (CD39 antigen-like 4) (ER-UDPase)
Length = 427
Score = 155 bits (393), Expect = 1e-37
Identities = 115/376 (30%), Positives = 181/376 (47%), Gaps = 44/376 (11%)
Query: 45 YAVVFDAGSTGSRIHVYHFDQNLDLLHIGKDVEFFNKITPGLSSYANDPEQAAKSLIPLL 104
Y ++FDAGSTG+RIHVY F Q + E F+ + PGLS++ + P+Q A+++ LL
Sbjct: 48 YGIMFDAGSTGTRIHVYTFVQKTAGQLPFLEGEIFDSVKPGLSAFVDQPKQGAETVQELL 107
Query: 105 QQAENVVPIDLHHKTPIRLGATAGLRLLNGDASEKILQAVRDMFSNRSTFNVQPDAVSII 164
+ A++ +P +TP+ L ATAGLRLL ++ +L V ++F N S F V +VSI+
Sbjct: 108 EVAKDSIPRSHWERTPVVLKATAGLRLLPEQKAQALLLEVEEIFKN-SPFLVPDGSVSIM 166
Query: 165 DGTQEGSYLWVTVNYALGNLGKKYTKTVGVMDLGGGSVQMAYAVS-KKTAKNAPKVADGV 223
DG+ EG WVTVN+ G L + +TVG +DLGG S Q+ + +KT + P+
Sbjct: 167 DGSYEGILAWVTVNFLTGQLHGRGQETVGTLDLGGASTQITFLPQFEKTLEQTPR----- 221
Query: 224 DPYIKKLVLKGKPYDLYVHSYLHFGREASRAEIMKVTRSS-------PNPCLLAGFDGTY 276
Y+ + + LY HSYL FG +A+R + + + CL + +
Sbjct: 222 -GYLTSFEMFNSTFKLYTHSYLGFGLKAARLATLGALEAKGTDGHTFRSACLPRWLEAEW 280
Query: 277 TYAGEEFKAKAPASG-ANFNGCKKIIRKAL--KLNYPCPYQNCTFGGIWNGGGGNGQKHL 333
+ G +++ G F C + + + KL+ P + F
Sbjct: 281 IFGGVKYQYGGNQEGEMGFEPCYAEVLRVVQGKLHQPEEVRGSAF--------------- 325
Query: 334 FASSSFFYLPEDVGMVDPKTPNFKIRPVDLVSEAKKACALNFEDAKSTYPFLAKKNIASY 393
+A S ++ D ++D + ++ D +A++ C N S PFL
Sbjct: 326 YAFSYYYDRAADTHLIDYEKGGV-LKVEDFERKAREVCD-NLGSFSSGSPFL-------- 375
Query: 394 VCMDLIYQYVLLVDGF 409
CMDL Y LL DGF
Sbjct: 376 -CMDLTYITALLKDGF 390
>ENP6_HUMAN (O75354) Ectonucleoside triphosphate diphosphohydrolase
6 (EC 3.6.1.6) (NTPDase6) (CD39 antigen-like 2)
Length = 484
Score = 155 bits (392), Expect = 2e-37
Identities = 117/376 (31%), Positives = 181/376 (48%), Gaps = 52/376 (13%)
Query: 45 YAVVFDAGSTGSRIHVYHFD----QNLDLLHIGKDVEFFNKITPGLSSYANDPEQAAKSL 100
Y ++FDAGSTG+R+HV+ F + L H E F + PGLS+YA+D E++A+ +
Sbjct: 102 YGIMFDAGSTGTRVHVFQFTRPPRETPTLTH-----ETFKALKPGLSAYADDVEKSAQGI 156
Query: 101 IPLLQQAENVVPIDLHHKTPIRLGATAGLRLLNGDASEKILQAVRDMFSNRSTFNVQPDA 160
LL A+ +P D TP+ L ATAGLRLL G+ ++K+LQ V+++F S F V D
Sbjct: 157 RELLDVAKQDIPFDFWKATPLVLKATAGLRLLPGEKAQKLLQKVKEVF-KASPFLVGDDC 215
Query: 161 VSIIDGTQEGSYLWVTVNYALGNLGKKYTKTVGVMDLGGGSVQMAYAVSKKTAKNAPKVA 220
VSI++GT EG W+T+N+ G+L +VG++DLGGGS Q+A+ + A
Sbjct: 216 VSIMNGTDEGVSAWITINFLTGSLKTPGGSSVGMLDLGGGSTQIAFLPRVEGTLQASPPG 275
Query: 221 DGVDPYIKKLVLKGKPYDLYVHSYLHFGREASRAEIMKVTRSSP--------NPCLLAGF 272
Y+ L + + Y LY +SYL G ++R I+ P +PCL F
Sbjct: 276 -----YLTALRMFNRTYKLYSYSYLGLGLMSARLAILGGVEGQPAKDGKELVSPCLSPSF 330
Query: 273 DGTYTYAGEEFKAKAPASGANFNG-CKKIIRKALKLNYPCPYQNCTFGGIWNGGGGNGQK 331
G + +A ++ + A+ + C + + L+ + K
Sbjct: 331 KGEWEHAEVTYRVSGQKAAASLHELCAARVSEVLQNRVHRTEE---------------VK 375
Query: 332 HL--FASSSFFYLPEDVGMVDPKTPNFKIRPVDLVSEAKKACALNFEDAKSTYPFLAKKN 389
H+ +A S ++ L VG++D + + D AK C E + PF
Sbjct: 376 HVDFYAFSYYYDLAAGVGLIDAEKGG-SLVVGDFEIAAKYVCR-TLETQPQSSPF----- 428
Query: 390 IASYVCMDLIYQYVLL 405
CMDL Y +LL
Sbjct: 429 ----SCMDLTYVSLLL 440
>GDA1_KLULA (Q9HEM6) Guanosine-diphosphatase (EC 3.6.1.42) (GDPase)
Length = 522
Score = 151 bits (382), Expect = 3e-36
Identities = 122/336 (36%), Positives = 158/336 (46%), Gaps = 48/336 (14%)
Query: 20 TSSQYLGNNLLTNRKIFQKQETISS--YAVVFDAGSTGSRIHVYHFD---QNLDLLHIGK 74
T+ + NL + K + Y V+ DAGSTGSR+HVY FD Q L++
Sbjct: 70 TAKDHTSQNLESGSNSLSKSQCTEGHKYVVMIDAGSTGSRVHVYEFDVCTQPPTLIN--- 126
Query: 75 DVEFFNKITPGLSSYANDPEQAAKSLIPLLQQAENVVPIDLHHKTPIRLGATAGLRLLNG 134
E F + PGLSS+ D AAKSL PLL+ A + VP D + TP+ + ATAGLR+L
Sbjct: 127 --ETFEMLKPGLSSFDIDAVGAAKSLDPLLKIAMDAVPKDKRNCTPVAVKATAGLRMLGD 184
Query: 135 DASEKILQAVRDMFSNRSTFN-VQPDAVSIIDGTQEGSYLWVTVNYALGNLGK-KYTKTV 192
+ S KIL VR F V D VSI+DG +EG Y WVT NY LGN+G T
Sbjct: 185 EKSSKILAQVRKHLEQDYPFPVVDGDGVSIMDGEEEGVYAWVTANYLLGNIGAGSKLPTA 244
Query: 193 GVMDLGGGSVQMAYAVSKKTAKNAPKVADGVDPYIKKLVLKGKPYDLYVHSYLHF----G 248
V DLGGGS Q+ + S + K+ DG Y +L G Y LY S+L + G
Sbjct: 245 AVFDLGGGSTQIVFEPSFPPNE---KMVDGEHKY--ELSFGGHDYTLYQFSHLGYGLMQG 299
Query: 249 REASRAEIMKVTRSS--------------PNPCLLAGFDGTYTYAGEEFK-AKAPASGAN 293
R E++ V SS +PCL G T GE+ K + N
Sbjct: 300 RNKINTELVNVAISSGTITKGQTARTYELSSPCLPPG----TTAEGEKVKISDDEIYTVN 355
Query: 294 FNG--------CKKIIRKALKLNYPCPYQNCTFGGI 321
F G C+ + K L + C C+F GI
Sbjct: 356 FKGPKVPAGPQCRYLADKILNKDAKCNTPPCSFNGI 391
>ENP6_RAT (Q9ER31) Ectonucleoside triphosphate diphosphohydrolase 6
(EC 3.6.1.6) (NTPDase6) (CD39 antigen-like 2)
Length = 455
Score = 151 bits (382), Expect = 3e-36
Identities = 115/375 (30%), Positives = 179/375 (47%), Gaps = 51/375 (13%)
Query: 45 YAVVFDAGSTGSRIHVYHF----DQNLDLLHIGKDVEFFNKITPGLSSYANDPEQAAKSL 100
Y ++FDAGSTG+RIHV+ F + L H E F + PGLS+YA+D E++A+ +
Sbjct: 74 YGIMFDAGSTGTRIHVFQFARPPGETPTLTH-----ETFKALKPGLSAYADDVEKSAQGI 128
Query: 101 IPLLQQAENVVPIDLHHKTPIRLGATAGLRLLNGDASEKILQAVRDMFSNRSTFNVQPDA 160
LL A+ +P D TP+ L ATAGLRLL G+ ++K+LQ V+++F S F V D
Sbjct: 129 QELLNVAKQHIPYDFWKATPLVLKATAGLRLLPGEKAQKLLQKVKEVF-KASPFLVGDDC 187
Query: 161 VSIIDGTQEGSYLWVTVNYALGNLGKKYTKTVGVMDLGGGSVQMAYAVSKKTAKNAPKVA 220
VSI++GT EG W+TVN+ G+L + +VG++DLGGGS Q+ + + A
Sbjct: 188 VSIMNGTDEGVSAWITVNFLTGSLKTPGSSSVGMLDLGGGSTQITFLPRVEGTLQASPPG 247
Query: 221 DGVDPYIKKLVLKGKPYDLYVHSYLHFGREASRAEIMKVTRSSP--------NPCLLAGF 272
++ L + + + LY +SYL G ++R I+ P +PCL F
Sbjct: 248 -----HLTALQMFNRTFKLYSYSYLGLGLMSARLAILGGVEGKPAEDDKELVSPCLSPRF 302
Query: 273 DGTYTYAGEEFKAKAPASGANFNGCKKIIRKAL--KLNYPCPYQNCTFGGIWNGGGGNGQ 330
G + +A ++ + + C + + L K++ Q+ F
Sbjct: 303 RGKWEHAEVTYRISGQKAVGLYELCASRVSEVLRNKVHRTEEAQHVDF------------ 350
Query: 331 KHLFASSSFFYLPEDVGMVDPKTPNFKIRPVDLVSEAKKACALNFEDAKSTYPFLAKKNI 390
+A S ++ L G++D + + D AK C E + PF
Sbjct: 351 ---YAFSYYYDLAASFGLIDAEKGG-SLVVGDFEIAAKYVCR-TLETQPPSSPF------ 399
Query: 391 ASYVCMDLIYQYVLL 405
CMDL Y +LL
Sbjct: 400 ---ACMDLTYISLLL 411
>GDA1_ASPFU (Q8TGG8) Probable guanosine-diphosphatase (EC 3.6.1.42)
(GDPase)
Length = 558
Score = 145 bits (366), Expect = 2e-34
Identities = 111/352 (31%), Positives = 166/352 (46%), Gaps = 39/352 (11%)
Query: 39 QETISSYAVVFDAGSTGSRIHVYHFDQNLDLLHIGKDVEFFN---KITPGLSSYANDPEQ 95
++ + YA++ DAGS GSRIHVY F+ + +V F K GLSSY D E
Sbjct: 113 KKPLIQYALMIDAGSQGSRIHVYRFNNCGPSPELEDEVFFQTEPKKGGSGLSSYKEDAEG 172
Query: 96 AAKSLIPLLQQAENVVPIDLHHKTPIRLGATAGLRLLNGDASEKILQAVRDMFSNRSTFN 155
AAKSL PL++ A VP + +PI + ATAGLR+L + S+KIL AVR+ F
Sbjct: 173 AAKSLDPLMEVAMKNVPDEYKSCSPIAVKATAGLRMLGPELSQKILDAVRNRLETVYPFP 232
Query: 156 V---QPDAVSIIDGTQEGSYLWVTVNYALGNL-GKKYTKTVGVMDLGGGSVQMAYAVSKK 211
V + V I+DG+ EG Y W+T NY LG + G T T V DLGGGS Q+ + +
Sbjct: 233 VVSKEKGGVEIMDGSDEGVYAWITTNYLLGKIGGPDETPTAAVFDLGGGSTQIVFQPTFP 292
Query: 212 TAKNA---PKVADGVDPYIKKLVLKGKPYDLYVHSYLHFGREASR--------------- 253
+K+ ++++G Y L G+ ++LY HS+L +G A+R
Sbjct: 293 KSKSGGMPERLSEGDHKY--DLQFGGRHFELYQHSHLGYGLMAARKAIHTSIIENMLASS 350
Query: 254 -AEIMKVTRSSPNPCLLAGFDGTYTYAGEEFKAKA---------PASGANFNGCKKIIRK 303
++ + + PNPC+ + T E A P G+ C+ + K
Sbjct: 351 PKDLSWLKQPIPNPCIGPEMEKNVTLEFPEGHKLAPEVQVTMVGPKVGSTAAQCRGLAEK 410
Query: 304 ALKLNYPCPYQNCTFGGIWNGGGGN--GQKHLFASSSFFYLPEDVGMVDPKT 353
L C C+F G+ ++ ++ S F+ + +GM D T
Sbjct: 411 TLNKEAACTLAPCSFNGVHQPSLEKTFAREDVYIFSYFYDRTKPLGMPDSFT 462
>GDA1_YEAST (P32621) Guanosine-diphosphatase (EC 3.6.1.42) (GDPase)
Length = 518
Score = 143 bits (360), Expect = 9e-34
Identities = 128/400 (32%), Positives = 178/400 (44%), Gaps = 51/400 (12%)
Query: 45 YAVVFDAGSTGSRIHVYHFDQNLD---LLHIGKDVEFFNKITPGLSSYANDPEQAAKSLI 101
Y ++ DAGSTGSR+H+Y FD LL E F+ + PGLSS+ D AA SL
Sbjct: 93 YVIMIDAGSTGSRVHIYKFDVCTSPPTLLD-----EKFDMLEPGLSSFDTDSVGAANSLD 147
Query: 102 PLLQQAENVVPIDLHHKTPIRLGATAGLRLLNGDASEKILQAVRDMFSNRSTFN-VQPDA 160
PLL+ A N VPI TP+ + ATAGLRLL S KIL AVRD F V+ D
Sbjct: 148 PLLKVAMNYVPIKARSCTPVAVKATAGLRLLGDAKSSKILSAVRDHLEKDYPFPVVEGDG 207
Query: 161 VSIIDGTQEGSYLWVTVNYALGNLGKKYTK--TVGVMDLGGGSVQMAYAVSKKTAKNAPK 218
VSI+ G +EG + W+T NY LGN+G K T V DLGGGS Q+ + + T K
Sbjct: 208 VSIMGGDEEGVFAWITTNYLLGNIGANGPKLPTAAVFDLGGGSTQIVF---EPTFPINEK 264
Query: 219 VADGVDPYIKKLVLKGKPYDLYVHSYLHFGREASRAEIMKV------------------T 260
+ DG + L + Y LY S+L +G + R ++ V T
Sbjct: 265 MVDGEHKF--DLKFGDENYTLYQFSHLGYGLKEGRNKVNSVLVENALKDGKILKGDNTKT 322
Query: 261 RSSPNPCLLAGFDGT---YTYAGEE-----FKAKAPASGANFNGCKKIIRKALKLNYPCP 312
+PCL + T T +E F SGA C+ + + L + C
Sbjct: 323 HQLSSPCLPPKVNATNEKVTLESKETYTIDFIGPDEPSGAQ---CRFLTDEILNKDAQCQ 379
Query: 313 YQNCTFGGIWNGGGGNGQKH---LFASSSFFYLPEDVGMVDPKTPNFKIRPVDLVSEAKK 369
C+F G+ K ++ S F+ +GM T N +V + ++
Sbjct: 380 SPPCSFNGVHQPSLVRTFKESNDIYIFSYFYDRTRPLGMPLSFTLNELNDLARIVCKGEE 439
Query: 370 ACALNFEDAKSTYPFLAKKNIASYVCMDLIYQYVLLVDGF 409
F + L + S+ C+DL +Q LL G+
Sbjct: 440 TWNSVFSGIAGS---LDELESDSHFCLDLSFQVSLLHTGY 476
>GDA1_CANAL (Q8TGH6) Guanosine-diphosphatase (EC 3.6.1.42) (GDPase)
Length = 599
Score = 139 bits (350), Expect = 1e-32
Identities = 113/343 (32%), Positives = 150/343 (42%), Gaps = 46/343 (13%)
Query: 45 YAVVFDAGSTGSRIHVYHFDQNLDLLHIGKDVEFFNKITPGLSSYANDPEQAAKSLIPLL 104
Y V+ DAGSTGSR+HVY F+ + + E F + PGLSS+ D AAKSL PLL
Sbjct: 163 YVVMIDAGSTGSRVHVYEFNTCVKPPQLLS--EEFEMLKPGLSSFDTDTVGAAKSLDPLL 220
Query: 105 QQAENVVPIDLHHKTPIRLGATAGLRLLNGDASEKILQAVRDMFSNRSTFN-VQPDAVSI 163
+ A VP + TP+ + ATAGLRLL S+ IL VR F V D +SI
Sbjct: 221 EVALKKVPKNKQSCTPVAVKATAGLRLLGETKSKAILDEVRSHLEKDYPFAVVSEDGISI 280
Query: 164 IDGTQEGSYLWVTVNYALGNL-GKKYTKTVGVMDLGGGSVQMAYAVSKKTAKNAPKVADG 222
+DG EG Y WVT NY LGN+ GK+ T V DLGGGS Q+ + K + DG
Sbjct: 281 MDGKDEGVYAWVTANYLLGNIGGKEKLPTAAVFDLGGGSTQIVFEPDYKVDE---VPVDG 337
Query: 223 VDPYIKKLVLKGKPYDLYVHSYLHFGREASRAEI------------------------MK 258
Y Y LY S+L +G R ++ K
Sbjct: 338 ETKY--HFTFGDNQYTLYQFSHLGYGLMQGRNKVNQLVLKNKLSELNLQKYTKKEVKGAK 395
Query: 259 VTRSSPNPCLLAGF---DGTYTYAGEEF---KAKAPASG----ANFNGCKKIIRKALKLN 308
T NPC+ G D +EF K P+S A + C+ + K L +
Sbjct: 396 ATVDVSNPCIPPGVVAKDVQVELGEDEFYVVNMKGPSSKDSTVAGGSQCRYLAEKVLNKD 455
Query: 309 YPCPYQNCTFGGIWNGG---GGNGQKHLFASSSFFYLPEDVGM 348
C + C+F G+ N ++ S F+ +GM
Sbjct: 456 AECTSKPCSFNGVHQPSLTRTFNKNSDMYVFSYFYDRTNPIGM 498
>ENP1_BOVIN (O18956) Ectonucleoside triphosphate diphosphohydrolase
1 (EC 3.6.1.5) (NTPDase1) (Ecto-ATP diphosphohydrolase)
(ATPDase) (Lymphoid cell activation antigen) (CD39
antigen) (Ecto-apyrase)
Length = 513
Score = 134 bits (337), Expect = 4e-31
Identities = 113/443 (25%), Positives = 203/443 (45%), Gaps = 79/443 (17%)
Query: 8 ITTVLLLLMPAITSSQYLGNNLLTNRKIFQKQETISSYAVVFDAGSTGSRIHVYHFDQNL 67
I V+ LL +T ++ L N+ + +V DAGS+ + +++Y +
Sbjct: 26 IIAVIALLALGLTQNKALPENV--------------KFGIVLDAGSSHTSLYIYRWPAEK 71
Query: 68 DL-LHIGKDVEFFNKITPGLSSYANDPEQAAKSLIPLLQQAENVVPIDLHHKTPIRLGAT 126
+ + +E N PG+S +A + L +++A+ V+P H +TP+ LGAT
Sbjct: 72 ENDTGVVTQIEESNVKGPGISGFAKKVNEINVYLTACMERAQKVIPSIQHMETPVYLGAT 131
Query: 127 AGLRLL---NGDASEKILQAVRDMFSNRSTFNVQPDAVSIIDGTQEGSYLWVTVNYALGN 183
AG+RLL N ++KIL AV S+ S + II G +EG+Y W+TVNY LG
Sbjct: 132 AGMRLLRMENKQMADKILAAVA---SSISEYPFDFQGARIISGQEEGAYGWITVNYLLGK 188
Query: 184 LGKKYT------------KTVGVMDLGGGSVQMAYAVSKKTAKNAPKVADGVDPYIKKLV 231
+K + +T G +DLGG S Q+ + +T ++ + Y +
Sbjct: 189 FTQKLSWFNLKPSKDDTQETYGALDLGGASTQITFVPQNETTESPNN-----NLYFR--- 240
Query: 232 LKGKPYDLYVHSYLHFGREASRAEIMKVTRSSPN-----PCLLAGF----------DGTY 276
L GK Y +Y HS+L +G++ + + + + N PC + + +G
Sbjct: 241 LYGKNYSVYTHSFLCYGKDQALLQKLALGLQGTNGIIHEPCFHSRYMRKIKMSVLNEGFC 300
Query: 277 TYAGEEFKAKAP------ASGANFNGCKKIIRKALKLNYPCPYQNCTFGGIW----NGGG 326
T E + P NF C++ I + +Y CPY +C+F G++ +G
Sbjct: 301 TKRHELNSSFYPLVDIEIRGAGNFQRCRQSIIQLFNTSY-CPYSSCSFNGVFLPPLHGQF 359
Query: 327 GNGQKHLFASSSFFYLPEDVGMVDPKTPNFKIRPVDLVSEAKKACALNFEDAKSTYPFLA 386
G A S+F+Y+ E + + ++ + + L + ++ CA +E+ + + +
Sbjct: 360 G-------AFSAFYYVMEFLNLTSEESVSVE----QLTEKLEEFCAQRWEEVQKNFGEVK 408
Query: 387 KKNIASYVCMDLIYQYVLLVDGF 409
+K ++ Y C Y VLL++G+
Sbjct: 409 EKYLSEY-CFSGTYILVLLLNGY 430
>ENP1_HUMAN (P49961) Ectonucleoside triphosphate diphosphohydrolase
1 (EC 3.6.1.5) (NTPDase1) (Ecto-ATP diphosphohydrolase)
(ATPDase) (Lymphoid cell activation antigen)
(Ecto-apyrase) (CD39 antigen)
Length = 510
Score = 133 bits (335), Expect = 7e-31
Identities = 116/444 (26%), Positives = 197/444 (44%), Gaps = 84/444 (18%)
Query: 8 ITTVLLLLMPAITSSQYLGNNLLTNRKIFQKQETISSYAVVFDAGSTGSRIHVYHF---- 63
I V+ LL +T ++ L N+ Y +V DAGS+ + +++Y +
Sbjct: 26 IIAVIALLAVGLTQNKALPENV--------------KYGIVLDAGSSHTSLYIYKWPAEK 71
Query: 64 DQNLDLLHIGKDVEFFNKITPGLSSYANDPEQAAKSLIPLLQQAENVVPIDLHHKTPIRL 123
+ + ++H VE PG+S + + L +++A V+P H +TP+ L
Sbjct: 72 ENDTGVVH---QVEECRVKGPGISKFVQKVNEIGIYLTDCMERAREVIPRSQHQETPVYL 128
Query: 124 GATAGLRLLNGDASE---KILQAVRDMFSNRSTFNVQPDAVSIIDGTQEGSYLWVTVNYA 180
GATAG+RLL ++ E ++L V SN F+ Q II G +EG+Y W+T+NY
Sbjct: 129 GATAGMRLLRMESEELADRVLDVVERSLSNYP-FDFQ--GARIITGQEEGAYGWITINYL 185
Query: 181 LGNLGKK------------YTKTVGVMDLGGGSVQMAYAVSKKTAKNAPKVADGVDPYIK 228
LG +K +T G +DLGG S Q+ + +T ++
Sbjct: 186 LGKFSQKTRWFSIVPYETNNQETFGALDLGGASTQVTFVPQNQTIESPDNAL-------- 237
Query: 229 KLVLKGKPYDLYVHSYLHFGR-EASRAEIMKVTRSSPN-----PCLLAGF-------DGT 275
+ L GK Y++Y HS+L +G+ +A ++ K + + N PC G+ D
Sbjct: 238 QFRLYGKDYNVYTHSFLCYGKDQALWQKLAKDIQVASNEILRDPCFHPGYKKVVNVSDLY 297
Query: 276 YTYAGEEFKAKAPASG------ANFNGCKKIIRKALKLNYPCPYQNCTFGGIW----NGG 325
T + F+ P N+ C + I + +Y CPY C F GI+ G
Sbjct: 298 KTPCTKRFEMTLPFQQFEIQGIGNYQQCHQSILELFNTSY-CPYSQCAFNGIFLPPLQGD 356
Query: 326 GGNGQKHLFASSSFFYLPEDVGMVDPKTPNFKIRPVDLVSEAKKACALNFEDAKSTYPFL 385
G A S+F+++ + + + K K+ + KK CA +E+ K++Y +
Sbjct: 357 FG-------AFSAFYFVMKFLNLTSEKVSQEKVTEM-----MKKFCAQPWEEIKTSYAGV 404
Query: 386 AKKNIASYVCMDLIYQYVLLVDGF 409
+K ++ Y C Y LL+ G+
Sbjct: 405 KEKYLSEY-CFSGTYILSLLLQGY 427
>ENP1_MOUSE (P55772) Ectonucleoside triphosphate diphosphohydrolase
1 (EC 3.6.1.5) (NTPDase1) (Ecto-ATP diphosphohydrolase)
(ATPDase) (Lymphoid cell activation antigen)
(Ecto-apyrase) (CD39 antigen)
Length = 510
Score = 128 bits (322), Expect = 2e-29
Identities = 103/435 (23%), Positives = 192/435 (43%), Gaps = 69/435 (15%)
Query: 6 TLITTVLLLLMPAITSSQYLGNNLLTNRKIFQKQETISSYAVVFDAGSTGSRIHVYHFDQ 65
T I V+ L+ +T ++ L N+ Y +V DAGS+ + +++Y +
Sbjct: 24 TSILAVIALIAVGLTQNKPLPENV--------------KYGIVLDAGSSHTNLYIYKWPA 69
Query: 66 NLDL-LHIGKDVEFFNKITPGLSSYANDPEQAAKSLIPLLQQAENVVPIDLHHKTPIRLG 124
+ + + +E PG+S YA ++ L ++ + ++P HH+TP+ LG
Sbjct: 70 EKENDTGVVQQLEECQVKGPGISKYAQKTDEIGAYLAECMELSTELIPTSKHHQTPVYLG 129
Query: 125 ATAGLRLLNGDASEKILQAVRDMFSNRSTFNVQPDAVSIIDGTQEGSYLWVTVNYALGNL 184
ATAG+RLL ++ + + + + ++ ++ II G +EG+Y W+T+NY LG
Sbjct: 130 ATAGMRLLRMESEQSADEVLAAVSTSLKSYPFDFQGAKIITGQEEGAYGWITINYLLGRF 189
Query: 185 GKKYT-----------KTVGVMDLGGGSVQMAYAVSKKTAKNAPKVADGVDPYIKKLVLK 233
++ + +T G +DLGG S Q+ + T ++ + L
Sbjct: 190 TQEQSWLSLISDSQKQETFGALDLGGASTQITFVPQNSTIESPENSL--------QFRLY 241
Query: 234 GKPYDLYVHSYLHFGREAS----RAEIMKVTRSS--PNPCLLAGFDGTY-------TYAG 280
G+ Y +Y HS+L +G++ + A+ ++V+ +PC G++ T
Sbjct: 242 GEDYTVYTHSFLCYGKDQALWQKLAKDIQVSSGGVLKDPCFNPGYEKVVNVSELYGTPCT 301
Query: 281 EEFKAKAPASGANFNG------CKKIIRKALKLNYPCPYQNCTFGGIW----NGGGGNGQ 330
+ F+ K P G C + I + N CPY C F G++ +G G
Sbjct: 302 KRFEKKLPFDQFRIQGTGDYEQCHQSILELFN-NSHCPYSQCAFNGVFLPPLHGSFG--- 357
Query: 331 KHLFASSSFFYLPEDVGMVDPKTPNFKIRPVDLVSEAKKACALNFEDAKSTYPFLAKKNI 390
A S+F+++ + V N I + K C+ ++E+ K++YP + +K +
Sbjct: 358 ----AFSAFYFVMDFFKKV---AKNSVISQEKMTEITKNFCSKSWEETKTSYPSVKEKYL 410
Query: 391 ASYVCMDLIYQYVLL 405
+ Y C Y LL
Sbjct: 411 SEY-CFSGAYILSLL 424
>YND1_YEAST (P40009) Golgi apyrase (EC 3.6.1.5) (ATP-diphosphatase)
(Adenosine diphosphatase) (ADPase)
(ATP-diphosphohydrolase) (Golgi nucleoside
diphosphatase)
Length = 630
Score = 126 bits (317), Expect = 9e-29
Identities = 98/351 (27%), Positives = 160/351 (44%), Gaps = 49/351 (13%)
Query: 39 QETISSYAVVFDAGSTGSRIHVYHFDQNLDLL---------------HIGKDVEFFNKIT 83
+ T + +V DAGS+GSRIHV+ + LL HI ++ ++ K+
Sbjct: 4 ENTNDRFGIVIDAGSSGSRIHVFKWQDTESLLHATNQDSQSILQSVPHIHQEKDWTFKLN 63
Query: 84 PGLSSYANDPEQAAKSLI-PLLQQAENVVPIDLHHKTPIRLGATAGLRLLNGDASEKILQ 142
PGLSS+ P+ A KS I PLL A+N++P P+ + ATAG+RLL D IL
Sbjct: 64 PGLSSFEKKPQDAYKSHIKPLLDFAKNIIPESHWSSCPVFIQATAGMRLLPQDIQSSILD 123
Query: 143 AVRDMFSNRSTFNVQPDA--VSIIDGTQEGSYLWVTVNYALGNLGKKYTK-----TVGVM 195
+ + + F V+ + + +IDG EG Y W+ +NY G+ + T G M
Sbjct: 124 GLCQGLKHPAEFLVEDCSAQIQVIDGETEGLYGWLGLNYLYGHFNDYNPEVSDHFTFGFM 183
Query: 196 DLGGGSVQMAYAV--SKKTAKNAPKVADGVDPYIKKLVLKGKPYDLYVHSYLHFGREASR 253
D+GG S Q+A+A S + A++ +A +++ + + +D++V ++L FG +R
Sbjct: 184 DMGGASTQIAFAPHDSGEIARHRDDIA---TIFLRSVNGDLQKWDVFVSTWLGFGANQAR 240
Query: 254 ----AEIMKV--------------TRSSPNPCLLAGFDGTYTYAGEEFKAKAPASGANFN 295
A+++ TR+ +PC+ G + + F A N+
Sbjct: 241 RRYLAQLINTLPENTNDYENDDFSTRNLNDPCMPRGSSTDFEFKDTIFHI---AGSGNYE 297
Query: 296 GCKKIIRKALKLNYPCPYQNCTFGGIWNGGGGNGQKHLFASSSFFYLPEDV 346
C K I L N PC + C F G+ +S ++Y DV
Sbjct: 298 QCTKSIYPLLLKNMPCDDEPCLFNGVHAPRIDFANDKFIGTSEYWYTANDV 348
>ENP2_CHICK (P79784) Ectonucleoside triphosphate diphosphohydrolase
2 (EC 3.6.1.3) (NTPDase2) (Ecto-ATPase) (CD39
antigen-like 1)
Length = 494
Score = 125 bits (315), Expect = 1e-28
Identities = 115/406 (28%), Positives = 179/406 (43%), Gaps = 70/406 (17%)
Query: 45 YAVVFDAGSTGSRIHVYHF------DQNLDLLHIGKDVEFFNKITPGLSSYANDPEQAAK 98
Y +V DAGS+ + + +Y + D + H DVE PG+SSY++ P A K
Sbjct: 37 YGIVLDAGSSHTAVFIYKWPADKENDTGVVSEHSMCDVE-----GPGISSYSSKPPAAGK 91
Query: 99 SLIPLLQQAENVVPIDLHHKTPIRLGATAGLRLLN--GDASEKILQAVRDMFSNRSTFNV 156
SL L QA VP + H TP+ LGATAG+RLL S+ L AV + ++
Sbjct: 92 SLEHCLSQAMRDVPKEKHADTPLYLGATAGMRLLTIADPPSQTCLSAV---MATLKSYPF 148
Query: 157 QPDAVSIIDGTQEGSYLWVTVNYALGNLGKK---------YTKTVGVMDLGGGSVQMAYA 207
I+ G +EG + W+T NY L N K+ KT+G MD GG S Q+ +
Sbjct: 149 DFGGAKILSGEEEGVFGWITANYLLENFIKRGWLGEWIQSKKKTLGAMDFGGASTQITFE 208
Query: 208 VSKKTAKNAPKVADGVDPYIKKLVLK--GKPYDLYVHSYLHFGREASRAEIM-KVTRSS- 263
S D ++ +++LK G+PY +Y HS+L +GR+ ++ KV ++
Sbjct: 209 TS-----------DAIEDPKNEVMLKLYGQPYKVYTHSFLCYGRDQVLKRLLSKVLQAEN 257
Query: 264 -----PNPCLLAGFDGTYTYA-------------GEEFKAKAPASG-ANFNGCKKIIRKA 304
NPC G+ + + + G SG N N C + K
Sbjct: 258 YQETVANPCWPTGYRKSLSLSSIYDSPCTEKERPGLPLNTTVVVSGTGNGNLCAVHVNKL 317
Query: 305 LKLNYPCPYQNCTFGGIWNGG-GGNGQKHLFASSSFFYLPEDVGMVDPKTPNFKIRPVDL 363
C + +C+F G++ GN A S+FFY + + V + + P DL
Sbjct: 318 FDFT-SCSFSHCSFDGVFQPEVSGN----FIAFSAFFYTVDFIRTVMERPVH---SPSDL 369
Query: 364 VSEAKKACALNFEDAKSTYPFLAKKNIASYVCMDLIYQYVLLVDGF 409
A+ CA ++ + P L +K + Y C + Y+L+ G+
Sbjct: 370 KDAAETICATSWNELYQKAPRL-EKRLPDY-CATSTFVYLLITKGY 413
>ENP1_RAT (P97687) Ectonucleoside triphosphate diphosphohydrolase 1
(EC 3.6.1.5) (NTPDase1) (Ecto-ATP diphosphohydrolase)
(ATPDase) (Lymphoid cell activation antigen)
(Ecto-apyrase) (CD39 antigen)
Length = 511
Score = 124 bits (312), Expect = 3e-28
Identities = 99/404 (24%), Positives = 186/404 (45%), Gaps = 63/404 (15%)
Query: 45 YAVVFDAGSTGSRIHVYHF----DQNLDLLHIGKDVEFFNKITPGLSSYANDPEQAAKSL 100
Y +V DAGS+ + +++Y + + + ++ + ++ + PG+S YA ++ A L
Sbjct: 49 YGIVLDAGSSHTNLYIYKWPAEKENDTGVVQLLEECQVKG---PGISKYAQKTDEIAAYL 105
Query: 101 IPLLQQAENVVPIDLHHKTPIRLGATAGLRLLNGDASEKILQAVRDMFSNRSTFNVQPDA 160
++ + +P H+TP+ LGATAG+RLL ++ + + + + + ++
Sbjct: 106 AECMKMSTERIPASKQHQTPVYLGATAGMRLLRMESKQSADEVLAAVSRSLKSYPFDFQG 165
Query: 161 VSIIDGTQEGSYLWVTVNYALGNLGKKYT-----------KTVGVMDLGGGSVQMAYAVS 209
II G +EG+Y W+T+NY LG ++ + T G +DLGG S Q+ +
Sbjct: 166 AKIITGQEEGAYGWITINYLLGRFTQEQSWLNFISDSQKQATFGALDLGGSSTQVTFVPL 225
Query: 210 KKTAKNAPKVADGVDPYIKKLVLKGKPYDLYVHSYLHFGREAS----RAEIMKVTRSS-- 263
+T + AP+ + + L G Y +Y HS+L +G++ + A+ ++V+
Sbjct: 226 NQTLE-APETS-------LQFRLYGTDYTVYTHSFLCYGKDQALWQKLAQDIQVSSGGIL 277
Query: 264 PNPCLLAGFDGTY-------TYAGEEFKAKAPASGANFNG------CKKIIRKALKLNYP 310
+PC G+ T + F+ K P + G C + I K N
Sbjct: 278 KDPCFYPGYKKVVNVSELYGTPCTKRFEKKLPFNQFQVQGTGDYEQCHQSILKFFN-NSH 336
Query: 311 CPYQNCTFGGIW----NGGGGNGQKHLFASSSFFYLPEDVGMVDPKTPNFKIRPVDLVSE 366
CPY C F G++ G G A S+F+++ + K N + + ++E
Sbjct: 337 CPYSQCAFNGVFLPPLQGSFG-------AFSAFYFVMD----FFKKMANDSVSSQEKMTE 385
Query: 367 -AKKACALNFEDAKSTYPFLAKKNIASYVCMDLIYQYVLLVDGF 409
K C+ +E+ K++YP + +K ++ Y C Y LL+ G+
Sbjct: 386 ITKNFCSKPWEEVKASYPTVKEKYLSEY-CFSGTYILSLLLQGY 428
>MI23_CAEEL (Q21815) Nucleoside-diphosphatase mig-23 (EC 3.6.1.-)
(NDPase) (Abnormal cell migration protein 23)
Length = 552
Score = 119 bits (299), Expect = 1e-26
Identities = 109/408 (26%), Positives = 179/408 (43%), Gaps = 56/408 (13%)
Query: 44 SYAVVFDAGSTGSRIHVYHFDQNLD--------LLHIGKDVEFFNKITPGLSSYANDPEQ 95
SY V+ DAGSTG+R+ VY++ D +++ K V KI+PGLS++ P Q
Sbjct: 43 SYGVICDAGSTGTRLFVYNWISTSDSELIQIEPVIYDNKPV--MKKISPGLSTFGTKPAQ 100
Query: 96 AAKSLIPLLQQAENVVPIDLHHKTPIRLGATAGLRLLNGDASEKILQAVRDMFSNRSTFN 155
AA+ L PL++ AE +P + TP+ + ATAG+RL+ + E +L+ +R+ ++
Sbjct: 101 AAEYLRPLMELAERHIPEEKRPYTPVFIFATAGMRLIPDEQKEAVLKNLRNKLPKITSMQ 160
Query: 156 VQPDAVSIIDGTQEGSYLWVTVNYALGNLGKKYT-------------KTVGVMDLGGGSV 202
V + + II+G EG Y W+ VNYALG K T KTVG++D+GG S
Sbjct: 161 VLKEHIRIIEGKWEGIYSWIAVNYALGKFNKTATLDFPGTSPAHARQKTVGMIDMGGASA 220
Query: 203 QMAY------AVSKKTAKNAPKVADGVDPYIKKLVLKGKPYDLYVHSYLHFG-----REA 251
Q+A+ + S +N D K Y L+V ++L +G R+
Sbjct: 221 QIAFELPDTDSFSSINVENINLGCREDDSLFK--------YKLFVTTFLGYGVNEGIRKY 272
Query: 252 SRAEIMKVTRSS----PNPCLLAGFDGTYTYA-GEEFKAKAPASGANFNGCKKIIRKAL- 305
+ K+ + + C+ T T GE F + N+N C ++K L
Sbjct: 273 EHMLLSKLKDQNGTVIQDDCMPLNLHKTVTLENGENFVRRGT---GNWNTCSNEVKKLLN 329
Query: 306 --KLNYPCPYQ--NCTFGGIWNGGGGNGQKHLFASSSFFYLPEDVGMVDPKTPNFKIRPV 361
+ C + C FG + ++ S ++Y DV + + I
Sbjct: 330 PESSSEVCKAEAAKCYFGAVPAPSIPLSNIEMYGFSEYWYSTHDVLGLGGQYDAENIAKK 389
Query: 362 DLVSEAKKACALNFEDAKSTYPFLAKKNIASYVCMDLIYQYVLLVDGF 409
+K+ + E K YP ++ + + C + +L DGF
Sbjct: 390 TQQYCSKRWSTIQAESKKQLYPRADEERLRTQ-CFKSAWITSVLHDGF 436
>ENP3_HUMAN (O75355) Ectonucleoside triphosphate diphosphohydrolase
3 (EC 3.6.1.5) (NTPDase3) (Ecto-ATP diphosphohydrolase)
(ATPDase) (Ecto-apyrase) (CD39 antigen-like 3) (HB6)
Length = 529
Score = 118 bits (295), Expect = 3e-26
Identities = 106/412 (25%), Positives = 181/412 (43%), Gaps = 62/412 (15%)
Query: 38 KQETIS---SYAVVFDAGSTGSRIHVYHFDQNLDLLHIGKDVEFFNKITPG--LSSYAND 92
KQE + Y +V DAGS+ + ++VY + + + G + F G +SSY N+
Sbjct: 47 KQEVLPPGLKYGIVLDAGSSRTTVYVYQWPAEKEN-NTGVVSQTFKCSVKGSGISSYGNN 105
Query: 93 PEQAAKSLIPLLQQAENVVPIDLHHKTPIRLGATAGLRLL---NGDASEKILQAVRDMFS 149
P+ ++ +Q+ + VP LH TPI LGATAG+RLL N A+ ++L++++ F
Sbjct: 106 PQDVPRAFEECMQKVKGQVPSHLHGSTPIHLGATAGMRLLRLQNETAANEVLESIQSYFK 165
Query: 150 NRSTFNVQPDAVSIIDGTQEGSYLWVTVNYALGNLGKKY----------TKTVGVMDLGG 199
++ F+ + II G +EG Y W+T NY +GN +K +T G +DLGG
Sbjct: 166 SQ-PFDFR--GAQIISGQEEGVYGWITANYLMGNFLEKNLWHMWVHPHGVETTGALDLGG 222
Query: 200 GSVQMAYAVSKKTAKNAPKVADGVDPYIKKLVLKGKPYDLYVHSYLHFGR-EASRAEIMK 258
S Q+++ +K N I ++ L G Y LY HS+ +GR EA + +
Sbjct: 223 ASTQISFVAGEKMDLNTSD--------IMQVSLYGYVYTLYTHSFQCYGRNEAEKKFLAM 274
Query: 259 VTRSSP------NPCLLAGFDGTYTY---------AGEEFKAKAPASGANFNG------C 297
+ ++SP NPC + ++T + ++ P F G C
Sbjct: 275 LLQNSPTKNHLTNPCYPRDYSISFTMGHVFDSLCTVDQRPESYNPNDVITFEGTGDPSLC 334
Query: 298 KKIIRKALKLNYPCPYQNCTFGGIWNGGGGNGQKHLFASSSFFYLPEDVGMVDPKTPNFK 357
K+ + + C+F G++ + A + F+Y + + + +F
Sbjct: 335 KEKVASIFDFKACHDQETCSFDGVYQ---PKIKGPFVAFAGFYYTASALNL----SGSFS 387
Query: 358 IRPVDLVSEAKKACALNFEDAKSTYPFLAKKNIASYVCMDLIYQYVLLVDGF 409
+ + S C+ N+ P + SY C Y Y L V+G+
Sbjct: 388 LDTFN--SSTWNFCSQNWSQLPLLLPKFDEVYARSY-CFSANYIYHLFVNGY 436
Database: sprot
Posted date: Nov 25, 2004 10:54 AM
Number of letters in database: 59,974,054
Number of sequences in database: 164,201
Lambda K H
0.319 0.137 0.403
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 49,610,382
Number of Sequences: 164201
Number of extensions: 2229776
Number of successful extensions: 5307
Number of sequences better than 10.0: 43
Number of HSP's better than 10.0 without gapping: 31
Number of HSP's successfully gapped in prelim test: 12
Number of HSP's that attempted gapping in prelim test: 5182
Number of HSP's gapped (non-prelim): 45
length of query: 409
length of database: 59,974,054
effective HSP length: 113
effective length of query: 296
effective length of database: 41,419,341
effective search space: 12260124936
effective search space used: 12260124936
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 67 (30.4 bits)
Medicago: description of AC123593.9