BLAST2 result
BLASTP 2.2.2 [Dec-14-2001]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= AC122722.6 + phase: 0
(461 letters)
Database: sprot
164,201 sequences; 59,974,054 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
GTR8_HUMAN (Q9NY64) Solute carrier family 2, facilitated glucose... 83 1e-15
GTR8_RAT (Q9JJZ1) Solute carrier family 2, facilitated glucose t... 82 4e-15
GTR8_BOVIN (P58354) Solute carrier family 2, facilitated glucose... 82 4e-15
GTR8_MOUSE (Q9JIF3) Solute carrier family 2, facilitated glucose... 80 1e-14
GT10_HUMAN (O95528) Solute carrier family 2, facilitated glucose... 79 3e-14
GTR5_HUMAN (P22732) Solute carrier family 2, facilitated glucose... 75 4e-13
GTR5_MOUSE (Q9WV38) Solute carrier family 2, facilitated glucose... 74 8e-13
GLCP_SYNY3 (P15729) Glucose transport protein 74 1e-12
GTR6_HUMAN (Q9UGQ3) Solute carrier family 2, facilitated glucose... 73 2e-12
XYLE_ECOLI (P09098) D-xylose-proton symporter (D-xylose transpor... 71 5e-12
GTR2_CHICK (Q90592) Solute carrier family 2, facilitated glucose... 70 9e-12
XYLT_LACBR (O52733) D-xylose-proton symporter (D-xylose transpor... 69 2e-11
GTR5_RAT (P43427) Solute carrier family 2, facilitated glucose t... 69 2e-11
GTR3_CANFA (P47842) Solute carrier family 2, facilitated glucose... 68 4e-11
GTR2_MOUSE (P14246) Solute carrier family 2, facilitated glucose... 68 4e-11
YFIG_BACSU (P54723) Hypothetical metabolite transport protein yfiG 67 7e-11
HXTD_YEAST (P42833) Hexose transporter HXT14 67 7e-11
GTR3_SHEEP (P47843) Solute carrier family 2, facilitated glucose... 67 1e-10
GTR3_HUMAN (P11169) Solute carrier family 2, facilitated glucose... 67 1e-10
GTR3_BOVIN (P58352) Solute carrier family 2, facilitated glucose... 67 1e-10
>GTR8_HUMAN (Q9NY64) Solute carrier family 2, facilitated glucose
transporter, member 8 (Glucose transporter type 8)
(Glucose transporter type X1)
Length = 477
Score = 83.2 bits (204), Expect = 1e-15
Identities = 41/104 (39%), Positives = 64/104 (61%)
Query: 350 TAGALYLSVGGMLLFVFTFALGAGPVPGLLLTEIFPSRIRAKAMAFCMSVHWVINFFVGL 409
+ G +L+VG M LF+ FA+G GP+P LL++EIFP ++ A C+ +W++ F V
Sbjct: 367 SVGLAWLAVGSMCLFIAGFAVGWGPIPWLLMSEIFPLHVKGVATGICVLTNWLMAFLVTK 426
Query: 410 LFLRLLEKLGAQLLYSMFATFCIMAVIFVKRNVVETKGKSLQEI 453
F L+E L + + + FCI +V+F V ETKGK+L++I
Sbjct: 427 EFSSLMEVLRPYGAFWLASAFCIFSVLFTFSCVPETKGKTLEQI 470
Score = 38.5 bits (88), Expect = 0.037
Identities = 20/52 (38%), Positives = 31/52 (59%), Gaps = 4/52 (7%)
Query: 68 GLVVSICLGGALFGCLLSGWIADAVGRRRAFQLCALPMIIG-AAMSNKQLVW 118
G VV++ GA G +L GW+ D GR+ + LC++P + G A ++ Q VW
Sbjct: 73 GAVVTL---GAAAGGVLGGWLVDRAGRKLSLLLCSVPFVAGFAVITAAQDVW 121
>GTR8_RAT (Q9JJZ1) Solute carrier family 2, facilitated glucose
transporter, member 8 (Glucose transporter type 8)
(Glucose transporter type X1)
Length = 478
Score = 81.6 bits (200), Expect = 4e-15
Identities = 41/102 (40%), Positives = 63/102 (61%)
Query: 352 GALYLSVGGMLLFVFTFALGAGPVPGLLLTEIFPSRIRAKAMAFCMSVHWVINFFVGLLF 411
G +L+VG M LF+ FA+G GP+P LL++EIFP I+ A C+ +W + F V F
Sbjct: 370 GLAWLAVGSMCLFIAGFAVGWGPIPWLLMSEIFPLHIKGVATGVCVLTNWFMAFLVTKEF 429
Query: 412 LRLLEKLGAQLLYSMFATFCIMAVIFVKRNVVETKGKSLQEI 453
++E L + + A FCI++V+F V ETKG++L++I
Sbjct: 430 NSIMEILRPYGAFWLTAAFCILSVLFTLTFVPETKGRTLEQI 471
Score = 38.9 bits (89), Expect = 0.028
Identities = 51/176 (28%), Positives = 78/176 (43%), Gaps = 32/176 (18%)
Query: 30 VLVATITSFL----FGYHLGVVNEPLESI------SVDLGFNGNTLAEGLVVSICLGGAL 79
V +AT + L FG+ LG + + S+ ++ LG +T A + LG A
Sbjct: 26 VFLATFAAALGPLSFGFALGYSSPAIPSLRRTAPPALRLG---DTAASWFGAVVTLGAAA 82
Query: 80 FGCLLSGWIADAVGRRRAFQLCALPMIIGAAMSNKQLVWHACRKIICWNWLG---LGPSR 136
G +L GW+ D GR+ + LC +P + G A V A R + W LG L
Sbjct: 83 GG-VLGGWLLDRAGRKLSLLLCTVPFVTGFA------VITAARDV--WMLLGGRLLTGLA 133
Query: 137 C--CSLCDRAYGALIQIATCFGILGSLFIGIPVKEISG-CLPYLQLYLL-WLWSSV 188
C SL Y + I G+LGS + + ++G L Y+ ++L W W +V
Sbjct: 134 CGVASLVAPVYISEIAYPAVRGLLGSC---VQLMVVTGILLAYVAGWVLEWRWLAV 186
>GTR8_BOVIN (P58354) Solute carrier family 2, facilitated glucose
transporter, member 8 (Glucose transporter type 8)
(Glucose transporter type X1) (Fragment)
Length = 334
Score = 81.6 bits (200), Expect = 4e-15
Identities = 41/102 (40%), Positives = 61/102 (59%)
Query: 352 GALYLSVGGMLLFVFTFALGAGPVPGLLLTEIFPSRIRAKAMAFCMSVHWVINFFVGLLF 411
G +L+VG M LF+ FA+G GP+P LL++EIFP ++ A C+ +W + F V F
Sbjct: 226 GLAWLAVGNMCLFIAGFAVGWGPIPWLLMSEIFPLHVKGVATGVCVLTNWFMAFLVTKEF 285
Query: 412 LRLLEKLGAQLLYSMFATFCIMAVIFVKRNVVETKGKSLQEI 453
L+E L + + + FCI V+F V ETKGK+L++I
Sbjct: 286 SSLMEVLRPYGAFWLASAFCIFGVLFTLACVPETKGKTLEQI 327
>GTR8_MOUSE (Q9JIF3) Solute carrier family 2, facilitated glucose
transporter, member 8 (Glucose transporter type 8)
(Glucose transporter type X1)
Length = 477
Score = 80.1 bits (196), Expect = 1e-14
Identities = 38/102 (37%), Positives = 62/102 (60%)
Query: 352 GALYLSVGGMLLFVFTFALGAGPVPGLLLTEIFPSRIRAKAMAFCMSVHWVINFFVGLLF 411
G +L+VG M LF+ FA+G GP+P LL++EIFP ++ A C+ +W + F V F
Sbjct: 369 GLAWLAVGSMCLFIAGFAVGWGPIPWLLMSEIFPLHVKGVATGICVLTNWFMAFLVTKEF 428
Query: 412 LRLLEKLGAQLLYSMFATFCIMAVIFVKRNVVETKGKSLQEI 453
++E L + + A FC ++V+F V ETKG++L+++
Sbjct: 429 SSVMEMLRPYGAFWLTAAFCALSVLFTLTVVPETKGRTLEQV 470
Score = 39.7 bits (91), Expect = 0.016
Identities = 49/169 (28%), Positives = 76/169 (43%), Gaps = 28/169 (16%)
Query: 33 ATITSFLFGYHLGVVNEPLESI------SVDLGFNGNTLAEGLVVSICLGGALFGCLLSG 86
A + FG+ LG + + S+ ++ LG N + G VV++ GA G +L G
Sbjct: 33 AALGPLSFGFALGYSSPAIPSLRRTAPPALRLGDNAASWF-GAVVTL---GAAAGGILGG 88
Query: 87 WIADAVGRRRAFQLCALPMIIGAAMSNKQLVWHACRKIICWNWLG---LGPSRC--CSLC 141
W+ D GR+ + LC +P + G A V A R + W LG L C SL
Sbjct: 89 WLLDRSGRKLSLLLCTVPFVTGFA------VITAARDV--WMLLGGRLLTGLACGVASLV 140
Query: 142 DRAYGALIQIATCFGILGSLFIGIPVKEISG-CLPYLQLYLL-WLWSSV 188
Y + I G+LGS + + ++G L Y+ ++L W W +V
Sbjct: 141 APVYISEIAYPAVRGLLGSC---VQLMVVTGILLAYVAGWVLEWRWLAV 186
>GT10_HUMAN (O95528) Solute carrier family 2, facilitated glucose
transporter, member 10 (Glucose transporter type 10)
Length = 541
Score = 78.6 bits (192), Expect = 3e-14
Identities = 37/94 (39%), Positives = 58/94 (61%)
Query: 361 MLLFVFTFALGAGPVPGLLLTEIFPSRIRAKAMAFCMSVHWVINFFVGLLFLRLLEKLGA 420
+++FV F+ G GPV L+L+EI+P IR +A AFC S +W N F+ L FL L+ +G
Sbjct: 416 LMVFVSAFSFGFGPVTWLVLSEIYPVEIRGRAFAFCNSFNWAANLFISLSFLDLIGTIGL 475
Query: 421 QLLYSMFATFCIMAVIFVKRNVVETKGKSLQEIE 454
+ ++ ++ + F+ V ETKG+SL EI+
Sbjct: 476 SWTFLLYGLTAVLGLGFIYLFVPETKGQSLAEID 509
Score = 42.7 bits (99), Expect = 0.002
Identities = 48/181 (26%), Positives = 75/181 (40%), Gaps = 16/181 (8%)
Query: 32 VATITSFLFGYHLGVVNEPLESISVDLGFNGNTLAEGLVVSICLGGALFGCLLSGWIADA 91
V+ + FGY L V++ L + +D G + L + +V L GAL L+ G++ D
Sbjct: 14 VSLLGGLTFGYELAVISGALLPLQLDFGLS--CLEQEFLVGSLLLGALLASLVGGFLIDC 71
Query: 92 VGRRRAFQLCALPMIIGAAMSN--KQLVWHACRKIICWNWLGLGPSRCCSLCDRAYGALI 149
GR++A L ++ G+ L W + + + L CC G
Sbjct: 72 YGRKQAILGSNLVLLAGSLTLGLAGSLAWLVLGRAVVGFAISLSSMACCIYVSELVGPRQ 131
Query: 150 QIATCFGILGSLF-IGIPVK-EISGCLPYLQLYLLWLWSSVQRVHIGYTSKEELLKQKLS 207
+ G+L SL+ GI V +S L Y W W R G+ + +L Q LS
Sbjct: 132 R-----GVLVSLYEAGITVGILLSYALNYALAGTPWGW----RHMFGWATAPAVL-QSLS 181
Query: 208 L 208
L
Sbjct: 182 L 182
>GTR5_HUMAN (P22732) Solute carrier family 2, facilitated glucose
transporter, member 5 (Glucose transporter type 5, small
intestine) (Fructose transporter)
Length = 501
Score = 75.1 bits (183), Expect = 4e-13
Identities = 122/473 (25%), Positives = 187/473 (38%), Gaps = 62/473 (13%)
Query: 25 LSLPHVLVATITSFLFGYHLGVVNEPLESIS-----VDLGFNGN-------TLAEGLVVS 72
L+L ++ A +SF +GY++ VN P + G G TL + VS
Sbjct: 17 LALATLIAAFGSSFQYGYNVAAVNSPALLMQQFYNETYYGRTGEFMEDFPLTLLWSVTVS 76
Query: 73 ICLGGALFGCLLSGWIADAVGRRRAFQLCALPMIIGAAMSNKQLVWHACRKIICWNWL-G 131
+ G G LL G + + GR+ A + I+ A + V + II L G
Sbjct: 77 MFPFGGFIGSLLVGPLVNKFGRKGALLFNNIFSIVPAILMGCSRVATSFELIIISRLLVG 136
Query: 132 LGPSRCCSLCDRAYGALI--QIATCFGILGSLFI--GIPVKEI----------------- 170
+ ++ G L + G++ LFI GI V +I
Sbjct: 137 ICAGVSSNVVPMYLGELAPKNLRGALGVVPQLFITVGILVAQIFGLRNLLANVDGWPILL 196
Query: 171 --SGCLPYLQLYLLWLWSSVQRVHIGYTSKEELLKQKLSLKDFWVYPKQNLRCHSYPR*I 228
+G LQL LL + R + E K+ L W + +
Sbjct: 197 GLTGVPAALQLLLLPFFPESPRYLLIQKKDEAAAKKALQTLRGWDSVDREV-AEIRQEDE 255
Query: 229 EEKILTL*SSLNCFMAIILKLFLLDQPYLLYNSYL--V*TLCFISLQLFLK--VPECHRI 284
EK S L F L+ LL L+ L V + + + Q++L VPE H +
Sbjct: 256 AEKAAGFISVLKLFRMRSLRWQLLSIIVLMGGQQLSGVNAIYYYADQIYLSAGVPEEH-V 314
Query: 285 LQTSA*ELRI*QDLSFRRV*WINLEGR----FYSFGVSLA*KRF*LYIFCTV*AISMIIQ 340
+A + ++F V + L GR F + L I C V ++ +Q
Sbjct: 315 QYVTAGTGAVNVVMTFCAVFVVELLGRRLLLLLGFSICL--------IACCVLTAALALQ 366
Query: 341 ATGASTLLPTAGALYLSVGGMLLFVFTFALGAGPVPGLLLTEIFPSRIRAKAMAFCMSVH 400
T + Y+S+ ++ +V ALG P+P LL+TEIF R A SVH
Sbjct: 367 DT-------VSWMPYISIVCVISYVIGHALGPSPIPALLITEIFLQSSRPSAFMVGGSVH 419
Query: 401 WVINFFVGLLFLRLLEKLGAQLLYSMFATFCIMAVIFVKRNVVETKGKSLQEI 453
W+ NF VGL+F + E LG + +FA C++ I++ V ETK K+ EI
Sbjct: 420 WLSNFTVGLIFPFIQEGLG-PYSFIVFAVICLLTTIYIFLIVPETKAKTFIEI 471
>GTR5_MOUSE (Q9WV38) Solute carrier family 2, facilitated glucose
transporter, member 5 (Glucose transporter type 5, small
intestine) (Fructose transporter)
Length = 501
Score = 73.9 bits (180), Expect = 8e-13
Identities = 47/139 (33%), Positives = 73/139 (51%), Gaps = 1/139 (0%)
Query: 315 FGVSLA*KRF*LYIFCTV*AISMIIQATGASTLLPTAGALYLSVGGMLLFVFTFALGAGP 374
F V L +RF L + + I+ ++ + + Y+S+ ++++V ALG P
Sbjct: 333 FVVELWGRRFLLLVGFSTCLIACLVLTAALALQNTISWMPYISIVCVIVYVIGHALGPSP 392
Query: 375 VPGLLLTEIFPSRIRAKAMAFCMSVHWVINFFVGLLFLRLLEKLGAQLLYSMFATFCIMA 434
+P LL+TEIF R A SVHW+ NF VGL+F + LG + +FAT C +
Sbjct: 393 IPALLITEIFLQSSRPAAYMIGGSVHWLSNFTVGLIFPFIQMGLG-PYSFIIFATICFLT 451
Query: 435 VIFVKRNVVETKGKSLQEI 453
I++ V ETKG++ EI
Sbjct: 452 TIYIFMVVPETKGRTFIEI 470
Score = 32.3 bits (72), Expect = 2.6
Identities = 26/94 (27%), Positives = 45/94 (47%), Gaps = 12/94 (12%)
Query: 16 KETTNPSWKLSLPHVLVATITSFLFGYHLGVVNEPLESISV---DLGFNGN--------- 63
+ET + L+L ++ A +SF +GY++ VN P E + D ++ N
Sbjct: 7 EETGELTLVLALATLIAAFGSSFQYGYNVAAVNSPSEFMQQFYNDTYYDRNEENIESFTL 66
Query: 64 TLAEGLVVSICLGGALFGCLLSGWIADAVGRRRA 97
TL L VS+ G L+ G + + +G++RA
Sbjct: 67 TLLWSLTVSMFPFGGFISSLVVGNLVNKLGKKRA 100
>GLCP_SYNY3 (P15729) Glucose transport protein
Length = 468
Score = 73.6 bits (179), Expect = 1e-12
Identities = 39/111 (35%), Positives = 63/111 (56%), Gaps = 2/111 (1%)
Query: 343 GASTLLPTAGALYLSVGGMLLFVFTFALGAGPVPGLLLTEIFPSRIRAKAMAFCMSVHWV 402
G TL AG + L L+VF+F GP+ +LL E+F ++IRA A++ V W+
Sbjct: 360 GQPTLTGAAGIIALVTAN--LYVFSFGFSWGPIVWVLLGEMFNNKIRAAALSVAAGVQWI 417
Query: 403 INFFVGLLFLRLLEKLGAQLLYSMFATFCIMAVIFVKRNVVETKGKSLQEI 453
NF + F LL+ +G Y ++AT +++ F+ V ETKGK+L+++
Sbjct: 418 ANFIISTTFPPLLDTVGLGPAYGLYATSAAISIFFIWFFVKETKGKTLEQM 468
Score = 45.4 bits (106), Expect = 3e-04
Identities = 41/131 (31%), Positives = 59/131 (44%), Gaps = 7/131 (5%)
Query: 32 VATITSFLFGYHLGVVNEPLESISVDLGFNGNTLAEGLVVSICLGGALFGCLLSGWIADA 91
VA + FLFG+ V+N + ++ F ++L GL VS+ L G+ G +G IAD
Sbjct: 23 VAALGGFLFGFDTAVINGAVAALQKH--FQTDSLLTGLSVSLALLGSALGAFGAGPIADR 80
Query: 92 VGRRRAFQLCALPMIIGAAMSNKQL-VWHACRKIICWNWLGLGPSRCCSLCDRAYGALIQ 150
GR + L A+ + + S +W I W LG S+ AY A +
Sbjct: 81 HGRIKTMILAAVLFTLSSIGSGLPFTIW----DFIFWRVLGGIGVGAASVIAPAYIAEVS 136
Query: 151 IATCFGILGSL 161
A G LGSL
Sbjct: 137 PAHLRGRLGSL 147
>GTR6_HUMAN (Q9UGQ3) Solute carrier family 2, facilitated glucose
transporter, member 6 (Glucose transporter type 6)
(Glucose transporter type 9)
Length = 507
Score = 72.8 bits (177), Expect = 2e-12
Identities = 39/112 (34%), Positives = 63/112 (55%), Gaps = 1/112 (0%)
Query: 344 ASTLLPTAGALYL-SVGGMLLFVFTFALGAGPVPGLLLTEIFPSRIRAKAMAFCMSVHWV 402
A L AG L L + +LF+ +A+G GP+ LL++E+ P R R A C+ W+
Sbjct: 384 AQPLAAPAGYLTLVPLLATMLFIMGYAVGWGPITWLLMSEVLPLRARGVASGLCVLASWL 443
Query: 403 INFFVGLLFLRLLEKLGAQLLYSMFATFCIMAVIFVKRNVVETKGKSLQEIE 454
F + FL ++ G Q+ + FA C+++++F V ETKG+SL++IE
Sbjct: 444 TAFVLTKSFLPVVSTFGLQVPFFFFAAICLVSLVFTGCCVPETKGRSLEQIE 495
>XYLE_ECOLI (P09098) D-xylose-proton symporter (D-xylose
transporter)
Length = 491
Score = 71.2 bits (173), Expect = 5e-12
Identities = 43/133 (32%), Positives = 69/133 (51%), Gaps = 6/133 (4%)
Query: 334 AISMIIQATGASTLLPTAGALYLSVGGMLLFVFTFALGAGPVPGLLLTEIFPSRIRAKAM 393
A+ M I T T +++ ML +V FA+ GPV +LL+EIFP+ IR KA+
Sbjct: 349 ALGMAIGMFSLGTAFYTQAPGIVALLSMLFYVAAFAMSWGPVCWVLLSEIFPNAIRGKAL 408
Query: 394 AFCMSVHWVINFFVGLLFLR------LLEKLGAQLLYSMFATFCIMAVIFVKRNVVETKG 447
A ++ W+ N+FV F L+ Y ++ ++A +F+ + V ETKG
Sbjct: 409 AIAVAAQWLANYFVSWTFPMMDKNSWLVAHFHNGFSYWIYGCMGVLAALFMWKFVPETKG 468
Query: 448 KSLQEIEIALLPQ 460
K+L+E+E P+
Sbjct: 469 KTLEELEALWEPE 481
Score = 41.2 bits (95), Expect = 0.006
Identities = 29/99 (29%), Positives = 49/99 (49%), Gaps = 8/99 (8%)
Query: 20 NPSWKLSLPHVLVATITSFLFGYHLGVVNEPLESISVDL--GFNGNTLAEGLVVSICLGG 77
N S+ S+ LVAT+ LFGY V++ +ES++ N + A ++ C+
Sbjct: 6 NSSYIFSI--TLVATLGGLLFGYDTAVISGTVESLNTVFVAPQNLSESAANSLLGFCVAS 63
Query: 78 ALFGCL----LSGWIADAVGRRRAFQLCALPMIIGAAMS 112
AL GC+ L G+ ++ GRR + ++ A+ I S
Sbjct: 64 ALIGCIIGGALGGYCSNRFGRRDSLKIAAVLFFISGVGS 102
>GTR2_CHICK (Q90592) Solute carrier family 2, facilitated glucose
transporter, member 2 (Glucose transporter type 2,
liver)
Length = 533
Score = 70.5 bits (171), Expect = 9e-12
Identities = 108/427 (25%), Positives = 162/427 (37%), Gaps = 56/427 (13%)
Query: 64 TLAEGLVVSICLGGALFGCLLSGWIADAVGRRRAFQLCALPMIIG------AAMSNKQLV 117
T+ L VS+ G + GWI D +GR +A + + I G A M ++
Sbjct: 106 TMYWSLSVSMFAVGGMVSSFTVGWIGDRLGRVKAMLVVNVLSIAGNLLMGLAKMGPSHIL 165
Query: 118 WHACRKII---CWNWLGLGPSRCCSLCDRAY----GALIQIATCFGILGSLFIGIP---- 166
A R I C GL P + A G L Q+A GIL S +G+
Sbjct: 166 IIAGRAITGLYCGLSSGLVPMYVSEVSPTALRGALGTLHQLAIVTGILISQVLGLDFLLG 225
Query: 167 -------VKEISGCLPYLQLYLLWLWSSVQRVHIGYTSKEELLKQKLS--------LKDF 211
+ +SG LQ +LL L R K E K+ L +K+
Sbjct: 226 NDELWPLLLGLSGVAALLQFFLLLLCPESPRYLYIKLGKVEEAKKSLKRLRGNCDPMKEI 285
Query: 212 WVYPKQNLRCHSYPR*IEEKILTL*SSLNCFMAIILKLFL-LDQPYLLYNSYLV*TLCFI 270
K+ S R I L SS A+I+ L + + Q + N+ + +
Sbjct: 286 AEMEKEKQEAASEKR---VSIGQLFSSSKYRQAVIVALMVQISQQFSGINA-----IFYY 337
Query: 271 SLQLFLKVPECHRILQTSA*ELRI*QDLSFRRV*WINLEGRFYS-FGVSLA*KRF*LYIF 329
S +F + + T V +N S F V A +R
Sbjct: 338 STNIFQRAGVGQPVYATIG-------------VGVVNTVFTVISVFLVEKAGRRSLFLAG 384
Query: 330 CTV*AISMIIQATGASTLLPTAGALYLSVGGMLLFVFTFALGAGPVPGLLLTEIFPSRIR 389
IS + G L A Y+S+ + LFV F +G GP+P ++ E+F R
Sbjct: 385 LMGMLISAVAMTVGLVLLSQFAWMSYVSMVAIFLFVIFFEVGPGPIPWFIVAELFSQGPR 444
Query: 390 AKAMAFCMSVHWVINFFVGLLFLRLLEKLGAQLLYSMFATFCIMAVIFVKRNVVETKGKS 449
A+A +W NF VG+ F + + G ++ +FA ++ +F V ETKGKS
Sbjct: 445 PAAIAVAGFCNWACNFIVGMCFQYIADLCG-PYVFVVFAVLLLVFFLFAYLKVPETKGKS 503
Query: 450 LQEIEIA 456
+EI A
Sbjct: 504 FEEIAAA 510
>XYLT_LACBR (O52733) D-xylose-proton symporter (D-xylose
transporter)
Length = 457
Score = 69.3 bits (168), Expect = 2e-11
Identities = 36/123 (29%), Positives = 64/123 (51%)
Query: 335 ISMIIQATGASTLLPTAGALYLSVGGMLLFVFTFALGAGPVPGLLLTEIFPSRIRAKAMA 394
IS+ + + G + A +SV + +++ F+ GPV +++ E+FP IR +
Sbjct: 320 ISLFVMSIGMKFSGGSQTAAIISVIALTVYIAFFSATWGPVMWVMIGEVFPLNIRGLGNS 379
Query: 395 FCMSVHWVINFFVGLLFLRLLEKLGAQLLYSMFATFCIMAVIFVKRNVVETKGKSLQEIE 454
F ++W N V L F LL+ G L+ + C ++ FV++ V ET+ +SL++IE
Sbjct: 380 FASVINWTANMIVSLTFPSLLDFFGTGSLFIGYGILCFASIWFVQKKVFETRNRSLEDIE 439
Query: 455 IAL 457
L
Sbjct: 440 ATL 442
Score = 40.0 bits (92), Expect = 0.013
Identities = 25/71 (35%), Positives = 37/71 (51%), Gaps = 2/71 (2%)
Query: 39 LFGYHLGVVNEPLESISVDLGFNGNTLAEGLVVSICLGGALFGCLLSGWIADAVGRRRAF 98
LFGY GV++ + I + N + +G VVS L GA+ G + G +D GRR+
Sbjct: 19 LFGYDTGVISGAILFIQKQM--NLGSWQQGWVVSAVLLGAILGAAIIGPSSDRFGRRKLL 76
Query: 99 QLCALPMIIGA 109
L A+ +GA
Sbjct: 77 LLSAIIFFVGA 87
>GTR5_RAT (P43427) Solute carrier family 2, facilitated glucose
transporter, member 5 (Glucose transporter type 5, small
intestine) (Fructose transporter)
Length = 502
Score = 69.3 bits (168), Expect = 2e-11
Identities = 37/99 (37%), Positives = 57/99 (57%), Gaps = 1/99 (1%)
Query: 355 YLSVGGMLLFVFTFALGAGPVPGLLLTEIFPSRIRAKAMAFCMSVHWVINFFVGLLFLRL 414
Y+S+ ++++V A+G P+P L +TEIF R A SVHW+ NF VGL+F +
Sbjct: 373 YVSIVCVIVYVIGHAVGPSPIPALFITEIFLQSSRPSAYMIGGSVHWLSNFIVGLIFPFI 432
Query: 415 LEKLGAQLLYSMFATFCIMAVIFVKRNVVETKGKSLQEI 453
LG + +FA C++ I++ V ETKG++ EI
Sbjct: 433 QVGLG-PYSFIIFAIICLLTTIYIFMVVPETKGRTFVEI 470
Score = 33.9 bits (76), Expect = 0.90
Identities = 26/85 (30%), Positives = 41/85 (47%), Gaps = 12/85 (14%)
Query: 25 LSLPHVLVATITSFLFGYHLGVVNEPLESISV---DLGFNGN---------TLAEGLVVS 72
L+L L A +SF +GY++ VN P E + D ++ N TL L VS
Sbjct: 16 LALATFLAAFGSSFQYGYNVAAVNSPSEFMQQFYNDTYYDRNKENIESFTLTLLWSLTVS 75
Query: 73 ICLGGALFGCLLSGWIADAVGRRRA 97
+ G G L+ G++ + +GR+ A
Sbjct: 76 MFPFGGFIGSLMVGFLVNNLGRKGA 100
>GTR3_CANFA (P47842) Solute carrier family 2, facilitated glucose
transporter, member 3 (Glucose transporter type 3,
brain)
Length = 495
Score = 68.2 bits (165), Expect = 4e-11
Identities = 36/99 (36%), Positives = 57/99 (57%), Gaps = 1/99 (1%)
Query: 355 YLSVGGMLLFVFTFALGAGPVPGLLLTEIFPSRIRAKAMAFCMSVHWVINFFVGLLFLRL 414
++ +G +L+FV F +G GP+P ++ E+F R AMA +W NF VGLLF
Sbjct: 364 FVCIGAILVFVAFFEIGPGPIPWFIVAELFSQGPRPAAMAVAGCSNWTSNFLVGLLFPSA 423
Query: 415 LEKLGAQLLYSMFATFCIMAVIFVKRNVVETKGKSLQEI 453
LGA ++ +F F I+ ++F V ET+G++ +EI
Sbjct: 424 AFYLGA-YVFIIFTGFLIVFLVFTFFKVPETRGRTFEEI 461
Score = 40.4 bits (93), Expect = 0.010
Identities = 43/169 (25%), Positives = 62/169 (36%), Gaps = 17/169 (10%)
Query: 32 VATITSFLFGYHLGVVNEPLESISVDLGFNGNTLAEGLVVSICLG------------GAL 79
+ATI SF FGY+ GV+N P I L + +E L + L G +
Sbjct: 16 IATIGSFQFGYNTGVINAPETIIKDFLNYTLEEKSENLPTEVLLTSLWSLSVAIFSVGGM 75
Query: 80 FGCLLSGWIADAVGRRRAFQLCALPMIIGAAMSNKQLVWHACRKIICWNW-LGLGPSRCC 138
G G + GRR + + L + G + + + +I +GL C
Sbjct: 76 IGSFSVGLFVNRFGRRNSMLMVNLLAVAGGCLMGFCKIAQSVEMLILGRLIIGLFCGLCT 135
Query: 139 SLCDRAYGALIQIAT--CFGILGSL--FIGIPVKEISGCLPYLQLYLLW 183
G + A FG L L IGI V +I G + LW
Sbjct: 136 GFVPMYIGEISPTALRGAFGTLNQLGIVIGILVAQIFGLKVIMGTEELW 184
>GTR2_MOUSE (P14246) Solute carrier family 2, facilitated glucose
transporter, member 2 (Glucose transporter type 2,
liver)
Length = 523
Score = 68.2 bits (165), Expect = 4e-11
Identities = 42/125 (33%), Positives = 62/125 (49%), Gaps = 7/125 (5%)
Query: 329 FCTV*AISMIIQATGASTLLPTAGALYLSVGGMLLFVFTFALGAGPVPGLLLTEIFPSRI 388
FCT I + G L A Y+S+ + LFV F +G GP+P ++ E F
Sbjct: 377 FCT------IFMSVGLVLLDKFAWMSYVSMTAIFLFVSFFEIGPGPIPWFMVAEFFSQGP 430
Query: 389 RAKAMAFCMSVHWVINFFVGLLFLRLLEKLGAQLLYSMFATFCIMAVIFVKRNVVETKGK 448
R A+A +WV NF + L F + + LG + + +FA ++ +F V ETKGK
Sbjct: 431 RPTALALAAFSNWVCNFVIALCFQYIADFLGPYVFF-LFAGVVLVFTLFTFFKVPETKGK 489
Query: 449 SLQEI 453
S +EI
Sbjct: 490 SFEEI 494
Score = 31.2 bits (69), Expect = 5.9
Identities = 13/25 (52%), Positives = 17/25 (68%)
Query: 30 VLVATITSFLFGYHLGVVNEPLESI 54
V A ++SF FGY +GV+N P E I
Sbjct: 14 VFTAVLSSFQFGYDIGVINAPQEVI 38
>YFIG_BACSU (P54723) Hypothetical metabolite transport protein yfiG
Length = 482
Score = 67.4 bits (163), Expect = 7e-11
Identities = 39/120 (32%), Positives = 63/120 (52%), Gaps = 8/120 (6%)
Query: 335 ISMIIQATGASTLLPTAGALYLSVGGMLLFVFTFALGAGPVPGLLLTEIFPSRIRAKAMA 394
+S++++ T A LP Y+ + +LF+ V L+L+EIFP +R M
Sbjct: 349 LSIVLEGTPA---LP-----YVVLSLTILFLAFQQTAISTVTWLMLSEIFPMHVRGLGMG 400
Query: 395 FCMSVHWVINFFVGLLFLRLLEKLGAQLLYSMFATFCIMAVIFVKRNVVETKGKSLQEIE 454
W NF +G F LL +G + +F I+A++FVK+ V ETKG+SL+++E
Sbjct: 401 ISTFCLWTANFLIGFTFPILLNHIGMSATFFIFVAMNILAILFVKKYVPETKGRSLEQLE 460
Score = 51.2 bits (121), Expect = 5e-06
Identities = 35/98 (35%), Positives = 47/98 (47%), Gaps = 3/98 (3%)
Query: 31 LVATITSFLFGYHLGVVNEPLESISVDLGFNGNTLAEGLVVSICLGGALFGCLLSGWIAD 90
LV+T LFGY GV+N L ++ N + EGLV S L GA FG + G ++D
Sbjct: 26 LVSTFGGLLFGYDTGVINGALPFMATAGQLNLTPVTEGLVASSLLLGAAFGAMFGGRLSD 85
Query: 91 AVGRRRAFQLCALPMI---IGAAMSNKQLVWHACRKII 125
GRR+ AL I +G S V A R ++
Sbjct: 86 RHGRRKTILYLALLFIAATLGCTFSPNASVMIAFRFLL 123
>HXTD_YEAST (P42833) Hexose transporter HXT14
Length = 540
Score = 67.4 bits (163), Expect = 7e-11
Identities = 37/97 (38%), Positives = 58/97 (59%), Gaps = 1/97 (1%)
Query: 364 FVFTFALGAGPVPGLLLTEIFPSRIRAKAMAFCMSVHWVINFFVGLLFLRLLEKLGAQLL 423
F+F FA+ GPV +L++E+FP R RA +MA C ++W+ NF + LL ++ K+ +L
Sbjct: 445 FIFWFAITLGPVTFVLVSELFPLRTRAISMAICTFINWMFNFLISLLTPMIVSKIDFKLG 504
Query: 424 YSMFATFCIMAVIFVKRNVVETKGKSLQEIEIALLPQ 460
Y +FA + +IF V ET+ K+ QEI P+
Sbjct: 505 Y-IFAACLLALIIFSWILVPETRKKNEQEINKIFEPE 540
>GTR3_SHEEP (P47843) Solute carrier family 2, facilitated glucose
transporter, member 3 (Glucose transporter type 3,
brain)
Length = 494
Score = 67.0 bits (162), Expect = 1e-10
Identities = 35/99 (35%), Positives = 56/99 (56%), Gaps = 1/99 (1%)
Query: 355 YLSVGGMLLFVFTFALGAGPVPGLLLTEIFPSRIRAKAMAFCMSVHWVINFFVGLLFLRL 414
++ +G +L+FV F +G GP+P ++ E+F R AMA +W NF VGLLF
Sbjct: 364 FICIGAILVFVAFFEIGPGPIPWFIVAELFGQGPRPAAMAVAGCSNWTSNFLVGLLFPSA 423
Query: 415 LEKLGAQLLYSMFATFCIMAVIFVKRNVVETKGKSLQEI 453
LGA ++ +F F ++ +F V ET+G++ +EI
Sbjct: 424 TFYLGA-YVFIVFTVFLVIFWVFTFFKVPETRGRTFEEI 461
Score = 40.8 bits (94), Expect = 0.007
Identities = 50/174 (28%), Positives = 67/174 (37%), Gaps = 23/174 (13%)
Query: 30 VLVATITSFLFGYHLGVVNEPLESISVDLGFNGNTLAE---------------GLVVSIC 74
+ +ATI SF FGY+ GV+N P E+I D F TL E L V+I
Sbjct: 14 ISIATIGSFQFGYNTGVINAP-EAIIKD--FLNYTLEERSETPPSSVLLTSLWSLSVAIF 70
Query: 75 LGGALFGCLLSGWIADAVGRRRAFQLCALPMIIGAAMSNKQLVWHACRKIICWNW-LGLG 133
G + G G + GRR + + L I G + + + +I +GL
Sbjct: 71 SVGGMIGSFSVGLFVNRFGRRNSMLIVNLLAIAGGCLMGFCKIAESVEMLILGRLIIGLF 130
Query: 134 PSRCCSLCDRAYGALIQIAT--CFGILGSL--FIGIPVKEISGCLPYLQLYLLW 183
C G + A FG L L IGI V +I G L LW
Sbjct: 131 CGLCTGFVPMYIGEISPTALRGAFGTLNQLGIVIGILVAQIFGLKVILGTEDLW 184
>GTR3_HUMAN (P11169) Solute carrier family 2, facilitated glucose
transporter, member 3 (Glucose transporter type 3,
brain)
Length = 496
Score = 67.0 bits (162), Expect = 1e-10
Identities = 36/102 (35%), Positives = 56/102 (54%), Gaps = 1/102 (0%)
Query: 352 GALYLSVGGMLLFVFTFALGAGPVPGLLLTEIFPSRIRAKAMAFCMSVHWVINFFVGLLF 411
G ++ +G +L+FV F +G GP+P ++ E+F R AMA +W NF VGLLF
Sbjct: 361 GMSFVCIGAILVFVAFFEIGPGPIPWFIVAELFSQGPRPAAMAVAGCSNWTSNFLVGLLF 420
Query: 412 LRLLEKLGAQLLYSMFATFCIMAVIFVKRNVVETKGKSLQEI 453
LGA ++ +F F I + F V ET+G++ ++I
Sbjct: 421 PSAAHYLGA-YVFIIFTGFLITFLAFTFFKVPETRGRTFEDI 461
Score = 40.8 bits (94), Expect = 0.007
Identities = 49/171 (28%), Positives = 65/171 (37%), Gaps = 17/171 (9%)
Query: 30 VLVATITSFLFGYHLGVVNEP----LESISVDLGFNGN--------TLAEGLVVSICLGG 77
+ VATI SF FGY+ GV+N P E I+ L GN T L V+I G
Sbjct: 14 ITVATIGSFQFGYNTGVINAPEKIIKEFINKTLTDKGNAPPSEVLLTSLWSLSVAIFSVG 73
Query: 78 ALFGCLLSGWIADAVGRRRAFQLCALPMIIGAAMSNKQLVWHACRKIICWNW-LGLGPSR 136
+ G G + GRR + + L + G V + +I +GL
Sbjct: 74 GMIGSFSVGLFVNRFGRRNSMLIVNLLAVTGGCFMGLCKVAKSVEMLILGRLVIGLFCGL 133
Query: 137 CCSLCDRAYGALIQIAT--CFGILGSL--FIGIPVKEISGCLPYLQLYLLW 183
C G + A FG L L +GI V +I G L LW
Sbjct: 134 CTGFVPMYIGEISPTALRGAFGTLNQLGIVVGILVAQIFGLEFILGSEELW 184
>GTR3_BOVIN (P58352) Solute carrier family 2, facilitated glucose
transporter, member 3 (Glucose transporter type 3,
brain)
Length = 494
Score = 67.0 bits (162), Expect = 1e-10
Identities = 35/99 (35%), Positives = 56/99 (56%), Gaps = 1/99 (1%)
Query: 355 YLSVGGMLLFVFTFALGAGPVPGLLLTEIFPSRIRAKAMAFCMSVHWVINFFVGLLFLRL 414
++ +G +L+FV F +G GP+P ++ E+F R AMA +W NF VGLLF
Sbjct: 364 FICIGAILVFVAFFEIGPGPIPWFIVAELFGQGPRPAAMAVAGCSNWTSNFLVGLLFPSA 423
Query: 415 LEKLGAQLLYSMFATFCIMAVIFVKRNVVETKGKSLQEI 453
LGA ++ +F F ++ +F V ET+G++ +EI
Sbjct: 424 AFYLGA-YVFIVFTVFLVIFWVFTFFKVPETRGRTFEEI 461
Score = 38.5 bits (88), Expect = 0.037
Identities = 50/174 (28%), Positives = 66/174 (37%), Gaps = 23/174 (13%)
Query: 30 VLVATITSFLFGYHLGVVNEPLESISVDLGFNGNTLAE---------------GLVVSIC 74
+ VATI SF FGY+ GV+N P E+I D F TL E L V+I
Sbjct: 14 ISVATIGSFQFGYNTGVINAP-EAIIKD--FLNYTLEERSEPPPSSVLLTSLWSLSVAIF 70
Query: 75 LGGALFGCLLSGWIADAVGRRRAFQLCALPMIIGAAMSNKQLVWHACRKIICWNW-LGLG 133
G + G G + GR + + L I G + + + +I +GL
Sbjct: 71 SVGGMIGSFSVGLFVNRFGRGNSMLIVNLLAIAGGCLMGFCKIAESVEMLILGRLIIGLF 130
Query: 134 PSRCCSLCDRAYGALIQIAT--CFGILGSL--FIGIPVKEISGCLPYLQLYLLW 183
C G + A FG L L IGI V +I G L LW
Sbjct: 131 CGLCTGFVPMYIGEISPTALRGAFGTLNQLGIVIGILVAQIFGLKVILGTEDLW 184
Database: sprot
Posted date: Nov 25, 2004 10:54 AM
Number of letters in database: 59,974,054
Number of sequences in database: 164,201
Lambda K H
0.341 0.151 0.500
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 49,100,304
Number of Sequences: 164201
Number of extensions: 1926214
Number of successful extensions: 6485
Number of sequences better than 10.0: 142
Number of HSP's better than 10.0 without gapping: 104
Number of HSP's successfully gapped in prelim test: 38
Number of HSP's that attempted gapping in prelim test: 6176
Number of HSP's gapped (non-prelim): 275
length of query: 461
length of database: 59,974,054
effective HSP length: 114
effective length of query: 347
effective length of database: 41,255,140
effective search space: 14315533580
effective search space used: 14315533580
T: 11
A: 40
X1: 15 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 39 (21.9 bits)
S2: 67 (30.4 bits)
Medicago: description of AC122722.6