BLAST2 result
BLASTP 2.2.2 [Dec-14-2001]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= AC122166.9 + phase: 0 /pseudo
(249 letters)
Database: sprot
164,201 sequences; 59,974,054 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
PRTZ_HORVU (P06293) Protein Z (Z4) (Major endosperm albumin) 161 1e-39
ANT3_MOUSE (P32261) Antithrombin-III precursor (ATIII) 94 3e-19
PTI6_HUMAN (P35237) Placental thrombin inhibitor (Cytoplasmic an... 92 2e-18
PAI1_RAT (P20961) Plasminogen activator inhibitor-1 precursor (P... 90 6e-18
ILEU_PIG (P80229) Leukocyte elastase inhibitor (LEI) (Leucocyte ... 88 2e-17
ANT3_SHEEP (P32262) Antithrombin-III precursor (ATIII) 86 1e-16
SB13_HUMAN (Q9UIV8) Hurpin (HaCaT UV-repressible serpin) (Protea... 85 1e-16
SPB8_HUMAN (P50452) Cytoplasmic antiproteinase 2 (CAP2) (CAP-2) ... 85 2e-16
PTI6_BOVIN (O02739) Serine proteinase inhibitor B-43 85 2e-16
OVAY_CHICK (P01014) Gene Y protein (Ovalbumin-related) 84 2e-16
PTI6_MOUSE (Q60854) Placental thrombin inhibitor (Protease inhib... 84 3e-16
PAI1_PIG (P79335) Plasminogen activator inhibitor-1 precursor (P... 83 7e-16
SPI2_HUMAN (O75830) Serpin I2 precursor (Myoepithelium-derived s... 82 9e-16
NEUS_RAT (Q9JLD2) Neuroserpin precursor (Protease inhibitor 17) 82 9e-16
ANT3_HUMAN (P01008) Antithrombin-III precursor (ATIII) (PRO0309) 82 9e-16
SPB9_HUMAN (P50453) Cytoplasmic antiproteinase 3 (CAP3) (CAP-3) ... 81 2e-15
PAI1_MUSVI (P50449) Plasminogen activator inhibitor-1 precursor ... 81 3e-15
ANT3_BOVIN (P41361) Antithrombin-III (ATIII) 80 4e-15
PAI1_MOUSE (P22777) Plasminogen activator inhibitor-1 precursor ... 80 5e-15
MASP_HUMAN (P36952) Maspin precursor (Protease inhibitor 5) 80 5e-15
>PRTZ_HORVU (P06293) Protein Z (Z4) (Major endosperm albumin)
Length = 399
Score = 161 bits (408), Expect = 1e-39
Identities = 93/226 (41%), Positives = 133/226 (58%), Gaps = 15/226 (6%)
Query: 17 SLTKFTNVSLNITKHLLSNQKLNEKNIVFSPLSLNTVLIMIATGSEGPTQNQLLSFLQSE 76
S+ T +L + + SN + N+ FSPLSL+ L +I G+ T++QL++ L
Sbjct: 12 SIAHQTRFALRLRSAISSNPERAAGNVAFSPLSLHVALSLITAGAAA-TRDQLVAILGDG 70
Query: 77 STGDLK---SLCSQVVSSVLSDGARAGGPCLSYVNGVWVEKSLPLQPSFKQLMTTDFEAT 133
GD K +L QVV VL++ + GGP +++ NG++V+ SL L+PSF++L ++A
Sbjct: 71 GAGDAKELNALAEQVVQFVLANESSTGGPRIAFANGIFVDASLSLKPSFEELAVCQYKAK 130
Query: 134 LSAVDFVNKA-----------EKKTKGLIQDLLPHGSVNSLTSLIFANALYFKGVWKQKF 182
+VDF +K E+ T GLI+ +LP GSV++ T LI NALYFKG W QKF
Sbjct: 131 TQSVDFQHKTLEAVGQVNSWVEQVTTGLIKQILPPGSVDNTTKLILGNALYFKGAWDQKF 190
Query: 183 DTSKTKDYDFDLLNGKSVKVPFMTSKNDQFISSLDGFKVLGLPINK 228
D S TK F LL+G S++ FM+S Q+ISS D KVL LP K
Sbjct: 191 DESNTKCDSFHLLDGSSIQTQFMSSTKKQYISSSDNLKVLKLPYAK 236
>ANT3_MOUSE (P32261) Antithrombin-III precursor (ATIII)
Length = 465
Score = 94.0 bits (232), Expect = 3e-19
Identities = 65/215 (30%), Positives = 105/215 (48%), Gaps = 18/215 (8%)
Query: 27 NITKHLLSNQKLNEKNIVFSPLSLNTVLIMIATGSEGPTQNQLLSFLQ----SESTGDLK 82
N +HL ++ N+ NI SPLS++T M G+ T QL+ + SE T D
Sbjct: 94 NFYQHLADSKNDND-NIFLSPLSISTAFAMTKLGACNDTLKQLMEVFKFDTISEKTSDQI 152
Query: 83 SLCSQVVSSVLSDGARAGGPCLSYVNGVWVEKSLPLQPSFKQLMTTDFEATLSAVDFVNK 142
++ L A +S N ++ +KSL S++ + + A L +DF
Sbjct: 153 HFFFAKLNCRLYRKANKSSDLVS-ANRLFGDKSLTFNESYQDVSEVVYGAKLQPLDFKEN 211
Query: 143 AEK-----------KTKGLIQDLLPHGSVNSLTSLIFANALYFKGVWKQKFDTSKTKDYD 191
E+ KT+G I+D++P G++N LT+L+ N +YFKG+WK KF T+
Sbjct: 212 PEQSRVTINNWVANKTEGRIKDVIPQGAINELTALVLVNTIYFKGLWKSKFSPENTRKEP 271
Query: 192 FDLLNGKSVKVPFMTSKND-QFISSLDGFKVLGLP 225
F ++G+S VP M + ++ +G +VL LP
Sbjct: 272 FYKVDGQSCPVPMMYQEGKFKYRRVAEGTQVLELP 306
>PTI6_HUMAN (P35237) Placental thrombin inhibitor (Cytoplasmic
antiproteinase) (CAP) (Protease inhibitor 6) (PI-6)
Length = 376
Score = 91.7 bits (226), Expect = 2e-18
Identities = 62/195 (31%), Positives = 99/195 (49%), Gaps = 20/195 (10%)
Query: 25 SLNITKHLLSNQKLNEKNIVFSPLSLNTVLIMIATGSEGPT---QNQLLSFLQSESTGDL 81
+LN+ K L K N KN+ FSP+S++ L M+ G++G T Q+LSF +S GD+
Sbjct: 12 ALNLLKTL---GKDNSKNVFFSPMSMSCALAMVYMGAKGNTAAQMAQILSFNKSGGGGDI 68
Query: 82 KSLCSQVVSSVLSDGARAGGPCLSYVNGVWVEKSLPLQPSFKQLMTTDFEATLSAVDFVN 141
+++ V G + L N ++ EKS SF+ ++A + +DF++
Sbjct: 69 HQGFQSLLTEVNKTGTQY---LLRVANRLFGEKSCDFLSSFRDSCQKFYQAEMEELDFIS 125
Query: 142 KAEK-----------KTKGLIQDLLPHGSVNSLTSLIFANALYFKGVWKQKFDTSKTKDY 190
EK KT+G I +LL GSV+ LT L+ NA+YF+G W ++FD T++
Sbjct: 126 AVEKSRKHINTWVAEKTEGKIAELLSPGSVDPLTRLVLVNAVYFRGNWDEQFDKENTEER 185
Query: 191 DFDLLNGKSVKVPFM 205
F + + V M
Sbjct: 186 LFKVSKNEEKPVQMM 200
>PAI1_RAT (P20961) Plasminogen activator inhibitor-1 precursor
(PAI-1) (Endothelial plasminogen activator inhibitor)
(PAI)
Length = 402
Score = 89.7 bits (221), Expect = 6e-18
Identities = 63/203 (31%), Positives = 101/203 (49%), Gaps = 24/203 (11%)
Query: 22 TNVSLNITKHLLSNQKLNEKNIVFSPLSLNTVLIMIATGSEGPTQNQL---LSFLQSE-- 76
TN + + +H++ K ++N+VFSP +++VL M+ + G T+ Q+ + F SE
Sbjct: 36 TNFGVKVFQHVVQASK--DRNVVFSPYGVSSVLAMLQLTTAGKTRQQIQDAMGFNISERG 93
Query: 77 STGDLKSLCSQVVSSVLSDGARAGGPCLSYVNGVWVEKSLPLQPSFKQLMTTDFEATLSA 136
+ L+ L +++ S + +S + ++V++ L L F F T+
Sbjct: 94 TAPALRKLSKELMGSWNKNE-------ISTADAIFVQRDLELVQGFMPHFFKLFRTTVKQ 146
Query: 137 VDF--VNKA--------EKKTKGLIQDLLPHGSVNSLTSLIFANALYFKGVWKQKFDTSK 186
VDF V +A E+ TKG+I DLL G+VN LT L+ NALYF G WK F +
Sbjct: 147 VDFSEVERARFIINDWVERHTKGMISDLLAKGAVNELTRLVLVNALYFNGQWKTPFLEAS 206
Query: 187 TKDYDFDLLNGKSVKVPFMTSKN 209
T F +G ++ VP M N
Sbjct: 207 THQRLFHKSDGSTISVPMMAQNN 229
>ILEU_PIG (P80229) Leukocyte elastase inhibitor (LEI) (Leucocyte
neutral proteinase inhibitor) (LNPI)
Length = 378
Score = 88.2 bits (217), Expect = 2e-17
Identities = 62/200 (31%), Positives = 100/200 (50%), Gaps = 18/200 (9%)
Query: 22 TNVSLNITKHLLSNQKLNEKNIVFSPLSLNTVLIMIATGSEGPTQNQLLSFLQSESTGDL 81
T +L++ + L N+ NI SP S+++ L MI G+ G T+ Q+ L ++ D+
Sbjct: 9 TRFALDLFRAL--NESNPAGNIFISPFSISSALAMILLGTRGNTEAQMSKALHFDTVKDI 66
Query: 82 KSLCSQVVSSVLSDGARAGGPCLSYVNGVWVEKSLPLQPSFKQLMTTDFEATLSAVDFVN 141
S + + + GA L N ++ EK+ P F + A L++VDF+
Sbjct: 67 HSRFQSLNADINKCGASY---ILKLANRLFGEKTYHFLPEFLASTQKTYGAELASVDFLR 123
Query: 142 KAEK-----------KTKGLIQDLLPHGSVNSLTSLIFANALYFKGVWKQKFDTSKTKDY 190
+E+ +T+G I +LL G V+S T L+ NA+YFKG W++KF T TKD
Sbjct: 124 ASEEARKAINEWVKEQTEGKIPELLASGVVDSATKLVLVNAIYFKGSWQEKFMTEATKDA 183
Query: 191 DFDL--LNGKSVKVPFMTSK 208
F L + K+VK+ + K
Sbjct: 184 PFRLNKKDSKTVKMMYQKKK 203
>ANT3_SHEEP (P32262) Antithrombin-III precursor (ATIII)
Length = 465
Score = 85.5 bits (210), Expect = 1e-16
Identities = 61/209 (29%), Positives = 98/209 (46%), Gaps = 17/209 (8%)
Query: 33 LSNQKLNEKNIVFSPLSLNTVLIMIATGSEGPTQNQLLSFLQ----SESTGDLKSLCSQV 88
L++ K N NI SPLS++T M G+ T QL+ + SE T D
Sbjct: 99 LADSKNNNDNIFLSPLSISTAFAMTKLGACNNTLKQLMEVFKFDTISEKTSDQIHFFFAK 158
Query: 89 VSSVLSDGARAGGPCLSYVNGVWVEKSLPLQPSFKQLMTTDFEATLSAVDFVNKAEK--- 145
++ L A +S N ++ +KS+ +++ + + A L +DF AE+
Sbjct: 159 LNCRLYRKANKSSELVS-ANRLFGDKSITFNETYQDISEVVYGAKLQPLDFKGNAEQSRL 217
Query: 146 --------KTKGLIQDLLPHGSVNSLTSLIFANALYFKGVWKQKFDTSKTKDYDFDLLNG 197
KT+G I D++P +++ T L+ N +YFKG+WK KF TK F +G
Sbjct: 218 TINQWISNKTEGRITDVIPPQAIDEFTVLVLVNTIYFKGLWKSKFSPENTKKELFYKADG 277
Query: 198 KSVKVPFMTSKND-QFISSLDGFKVLGLP 225
+S VP M + ++ +G +VL LP
Sbjct: 278 ESCSVPMMYQEGKFRYRRVAEGTQVLELP 306
>SB13_HUMAN (Q9UIV8) Hurpin (HaCaT UV-repressible serpin) (Protease
inhibitor 13) (Headpin) (Serpin B13)
Length = 391
Score = 85.1 bits (209), Expect = 1e-16
Identities = 65/231 (28%), Positives = 108/231 (46%), Gaps = 30/231 (12%)
Query: 22 TNVSLNITKHLLSNQKLNEKNIVFSPLSLNTVLIMIATGSEGPTQNQLLSFLQSES---T 78
T + ++ K L +K N+ NI FSP+ + T + M+ G+ G T +QL SE +
Sbjct: 9 TRLGFDLFKEL---KKTNDGNIFFSPVGILTAIGMVLLGTRGATASQLEEVFHSEKETKS 65
Query: 79 GDLKSLCSQVVSSV----------LSDGARAGGPC-LSYVNGVWVEKSLPLQPSFKQLMT 127
+K+ +V+ + L++ ++ L+ N ++ EK+ + +
Sbjct: 66 SRIKAEEKEVIENTEAVHQQFQKFLTEISKLTNDYELNITNRLFGEKTYLFLQKYLDYVE 125
Query: 128 TDFEATLSAVDFVNKA-----------EKKTKGLIQDLLPHGSVNSLTSLIFANALYFKG 176
+ A+L VDFVN A E KT I+DL P GS++S T L+ N +YFKG
Sbjct: 126 KYYHASLEPVDFVNAADESRKKINSWVESKTNEKIKDLFPDGSISSSTKLVLVNMVYFKG 185
Query: 177 VWKQKFDTSKTKDYDFDLLNGKSVKVPFMTSKNDQFISSLDGF--KVLGLP 225
W ++F TK+ F + S V MT + + L+ K+LG+P
Sbjct: 186 QWDREFKKENTKEEKFWMNKSTSKSVQMMTQSHSFSFTFLEDLQAKILGIP 236
>SPB8_HUMAN (P50452) Cytoplasmic antiproteinase 2 (CAP2) (CAP-2)
(Protease inhibitor 8) (Serpin B8)
Length = 374
Score = 84.7 bits (208), Expect = 2e-16
Identities = 60/215 (27%), Positives = 103/215 (47%), Gaps = 15/215 (6%)
Query: 23 NVSLNITKHLLSNQKLNEKNIVFSPLSLNTVLIMIATGSEGPTQNQLLSFLQSESTGDLK 82
N + I+ + ++ N +N+ FSP+S+++ L M+ G++G T Q+ L GD+
Sbjct: 8 NGTFAISLFKILGEEDNSRNVFFSPMSISSALAMVFMGAKGSTAAQMSQALCLYKDGDIH 67
Query: 83 SLCSQVVSSVLSDGARAGGPCLSYVNGVWVEKSLPLQPSFKQLMTTDFEATLSAVDFVNK 142
++S V G + L N ++ EK+ P FK+ ++A L + F
Sbjct: 68 RGFQSLLSEVNRTGTQY---LLRTANRLFGEKTCDFLPDFKEYCQKFYQAELEELSFAED 124
Query: 143 AEK-----------KTKGLIQDLLPHGSVNSLTSLIFANALYFKGVWKQKFDTSKTKDYD 191
E+ KT+G I ++L G+V+ LT L+ NA+YFKG W ++FD T+
Sbjct: 125 TEECRKHINDWVAEKTEGKISEVLDAGTVDPLTKLVLVNAIYFKGKWNEQFDRKYTRGML 184
Query: 192 FDL-LNGKSVKVPFMTSKNDQFISSLDGFKVLGLP 225
F K+V++ F +K + +VL LP
Sbjct: 185 FKTNEEKKTVQMMFKEAKFKMGYADEVHTQVLELP 219
>PTI6_BOVIN (O02739) Serine proteinase inhibitor B-43
Length = 378
Score = 84.7 bits (208), Expect = 2e-16
Identities = 56/183 (30%), Positives = 88/183 (47%), Gaps = 12/183 (6%)
Query: 39 NEKNIVFSPLSLNTVLIMIATGSEGPTQNQLLSFLQSESTGDLKSLCSQVVSSVLSDGAR 98
N KN+ SPLS+++ L M+ G++G T Q+ L + Q ++LS+ R
Sbjct: 23 NSKNVFISPLSISSALAMVLLGAKGNTAAQMCQTLSLNKSSGGGEDVHQGFQNLLSEVNR 82
Query: 99 AGGP-CLSYVNGVWVEKSLPLQPSFKQLMTTDFEATLSAVDFVNKAEK-----------K 146
L N ++ EK+ SFK ++A + +DFV+ E+ K
Sbjct: 83 RDTQYLLRTANRLFGEKTYDFLSSFKDSCHKFYQAEMEELDFVSATEQSRKHINTWVAEK 142
Query: 147 TKGLIQDLLPHGSVNSLTSLIFANALYFKGVWKQKFDTSKTKDYDFDLLNGKSVKVPFMT 206
T+G I+DLLP SVN +T L+ NA+YFKG W +F+ T++ F + V M
Sbjct: 143 TEGKIRDLLPANSVNPMTRLVLVNAIYFKGNWDTQFNKEHTEERPFRVSKNVEKPVQMMF 202
Query: 207 SKN 209
K+
Sbjct: 203 KKS 205
>OVAY_CHICK (P01014) Gene Y protein (Ovalbumin-related)
Length = 388
Score = 84.3 bits (207), Expect = 2e-16
Identities = 61/209 (29%), Positives = 103/209 (49%), Gaps = 24/209 (11%)
Query: 41 KNIVFSPLSLNTVLIMIATGSEGPTQNQLLSFLQSES-TGDLKSLCSQVVSS-------- 91
+NI++ PLS+ T L M+ G+ G T++Q+ L +S TG + SQ SS
Sbjct: 26 ENILYCPLSILTALAMVYLGARGNTESQMKKVLHFDSITGAGSTTDSQCGSSEYVHNLFK 85
Query: 92 -VLSDGARAGGP-CLSYVNGVWVEKSLPLQPSFKQLMTTDFEATLSAVDFVNKAE----- 144
+LS+ R L + ++V+K+ + P + + + V+F AE
Sbjct: 86 ELLSEITRPNATYSLEIADKLYVDKTFSVLPEYLSCARKFYTGGVEEVNFKTAAEEARQL 145
Query: 145 ------KKTKGLIQDLLPHGSVNSLTSLIFANALYFKGVWKQKFDTSKTKDYDFDLLNGK 198
K+T G I+DLL S++ T+++F N +YFKG+WK F+T T++ F + +
Sbjct: 146 INSWVEKETNGQIKDLLVSSSIDFGTTMVFINTIYFKGIWKIAFNTEDTREMPFSMTKEE 205
Query: 199 SVKVPFMTSKNDQFISSL--DGFKVLGLP 225
S V M N +++L + K+L LP
Sbjct: 206 SKPVQMMCMNNSFNVATLPAEKMKILELP 234
>PTI6_MOUSE (Q60854) Placental thrombin inhibitor (Protease
inhibitor 6) (PI-6)
Length = 378
Score = 84.0 bits (206), Expect = 3e-16
Identities = 59/198 (29%), Positives = 102/198 (50%), Gaps = 16/198 (8%)
Query: 25 SLNITKHLLSNQKLNEKNIVFSPLSLNTVLIMIATGSEGPTQNQLLSFLQSES-TGDLKS 83
+LN+ K L + + KN+ SP+S+++ L M+ G++G T +Q+ L + +G+
Sbjct: 12 ALNLLKILGED---SSKNVFLSPMSISSALAMVFMGAKGTTASQMAQALALDKCSGNGGG 68
Query: 84 LCSQVVSSVLSDGARAGGP-CLSYVNGVWVEKSLPLQPSFKQLMTTDFEATLSAVDFVNK 142
Q S+L++ + G L N ++ +K+ L SFK +EA L +DF
Sbjct: 69 DVHQGFQSLLTEVNKTGTQYLLRTANRLFGDKTCDLLASFKDSCLKFYEAELEELDFQGA 128
Query: 143 AE-----------KKTKGLIQDLLPHGSVNSLTSLIFANALYFKGVWKQKFDTSKTKDYD 191
E KKT+ I+++L G+VNS TSL+ NA+YFKG W+++F+ T++
Sbjct: 129 TEESRQHINTWVAKKTEDKIKEVLSPGTVNSDTSLVLVNAIYFKGNWEKQFNKEHTREMP 188
Query: 192 FDLLNGKSVKVPFMTSKN 209
F + + V M K+
Sbjct: 189 FKVSKNEEKPVQMMFKKS 206
>PAI1_PIG (P79335) Plasminogen activator inhibitor-1 precursor
(PAI-1) (Endothelial plasminogen activator inhibitor)
(PAI)
Length = 402
Score = 82.8 bits (203), Expect = 7e-16
Identities = 58/189 (30%), Positives = 86/189 (44%), Gaps = 22/189 (11%)
Query: 36 QKLNEKNIVFSPLSLNTVLIMIATGSEGPTQNQLLSFLQS--ESTG---DLKSLCSQVVS 90
Q ++N+VFSP + +VL M+ + G TQ Q+ +Q E G L+ L +++
Sbjct: 48 QASKDRNVVFSPYGVASVLAMLQLTTAGDTQQQIQEAMQFKIEEKGMAPALRQLYKELMG 107
Query: 91 SVLSDGARAGGPCLSYVNGVWVEKSLPLQPSFKQLMTTDFEATLSAVDFVNK-------- 142
D +S + ++V++ L L F F T+ VDF
Sbjct: 108 PWNKDE-------ISTADAIFVQRDLKLVQGFMPYFFRLFRTTVKQVDFSEMDRARFIIN 160
Query: 143 --AEKKTKGLIQDLLPHGSVNSLTSLIFANALYFKGVWKQKFDTSKTKDYDFDLLNGKSV 200
++ TKG+I DLL G+V+ LT L+ NALYF G WK F T F +G +V
Sbjct: 161 DWVKRHTKGMINDLLGQGAVDQLTRLVLVNALYFNGQWKTPFPEKSTHHRLFHKSDGSTV 220
Query: 201 KVPFMTSKN 209
VP M N
Sbjct: 221 SVPMMAQTN 229
>SPI2_HUMAN (O75830) Serpin I2 precursor (Myoepithelium-derived
serine protease inhibitor) (Pancpin) (Protease inhibitor
14) (TSA2004)
Length = 405
Score = 82.4 bits (202), Expect = 9e-16
Identities = 57/201 (28%), Positives = 97/201 (47%), Gaps = 17/201 (8%)
Query: 39 NEKNIVFSPLSLNTVLIMIATGSEGPTQNQLLSFL-QSESTGDLKSLCSQVVSSVLSDGA 97
++ NI+FSPL + VL M+ G++G Q Q+ L Q E++ + + S +S+
Sbjct: 41 HKDNIIFSPLGITLVLEMVQLGAKGKAQQQIRQTLKQQETSAGEEFFVLKSFFSAISEKK 100
Query: 98 RAGGPCLSYVNGVWVEKSLPLQPSFKQLMTTDFEATLSAVDFVNK----------AEKKT 147
+ + N +++++ ++ + F++ + VDF + E+KT
Sbjct: 101 QEF--TFNLANALYLQEGFTVKEQYLHGNKEFFQSAIKLVDFQDAKACAEMISTWVERKT 158
Query: 148 KGLIQDLLPHGSVNSLTSLIFANALYFKGVWKQKFDTSKTKDYDFDLLNGKSVKVPFM-- 205
G I+D+ LT L+ NA+YFKG WKQKF T+ +F NG +VK+P M
Sbjct: 159 DGKIKDMFSGEEFGPLTRLVLVNAIYFKGDWKQKFRKEDTQLINFTKKNGSTVKIPMMKA 218
Query: 206 --TSKNDQFISSLDGFKVLGL 224
+K F S ++VL L
Sbjct: 219 LLRTKYGYFSESSLNYQVLEL 239
>NEUS_RAT (Q9JLD2) Neuroserpin precursor (Protease inhibitor 17)
Length = 410
Score = 82.4 bits (202), Expect = 9e-16
Identities = 56/198 (28%), Positives = 98/198 (49%), Gaps = 17/198 (8%)
Query: 25 SLNITKHLLSNQKLNEKNIVFSPLSLNTVLIMIATGSEGPTQNQLLSFLQSES--TGDLK 82
S+N+ HL + + ++NI+FSPLS+ + ++ G++G T ++ + ES +G+
Sbjct: 30 SVNVYNHLRATGE--DENILFSPLSIALAMGVMELGAQGSTLKEIRHSMGYESLKSGEEF 87
Query: 83 SLCSQVVSSVLSDGARAGGPCLSYVNGVWVEKSLPLQPSFKQLMTTDFEATLSAVDF--- 139
S S V A G + N ++V+ + F Q+M F A ++ VDF
Sbjct: 88 SFLRDFSSMV---SAEEGQYVMKIANSLFVQNGFHINEEFLQMMKMYFNAEVNHVDFSEN 144
Query: 140 ------VNK-AEKKTKGLIQDLLPHGSVNSLTSLIFANALYFKGVWKQKFDTSKTKDYDF 192
+NK E T L++DL+ G +++T L NA+YFKG WK +F T+ + F
Sbjct: 145 VAVANYINKWVENYTNSLLKDLVSPGDFDAVTHLALINAVYFKGNWKSQFRPENTRTFSF 204
Query: 193 DLLNGKSVKVPFMTSKND 210
+ V++P M + +
Sbjct: 205 TKDDESEVQIPMMYQQGE 222
>ANT3_HUMAN (P01008) Antithrombin-III precursor (ATIII) (PRO0309)
Length = 464
Score = 82.4 bits (202), Expect = 9e-16
Identities = 60/209 (28%), Positives = 97/209 (45%), Gaps = 17/209 (8%)
Query: 33 LSNQKLNEKNIVFSPLSLNTVLIMIATGSEGPTQNQLLSFLQ----SESTGDLKSLCSQV 88
L++ K + NI SPLS++T M G+ T QL+ + SE T D
Sbjct: 98 LADSKNDNDNIFLSPLSISTAFAMTKLGACNDTLQQLMEVFKFDTISEKTSDQIHFFFAK 157
Query: 89 VSSVLSDGARAGGPCLSYVNGVWVEKSLPLQPSFKQLMTTDFEATLSAVDFVNKAEK--- 145
++ L A +S N ++ +KSL +++ + + A L +DF AE+
Sbjct: 158 LNCRLYRKANKSSKLVS-ANRLFGDKSLTFNETYQDISELVYGAKLQPLDFKENAEQSRA 216
Query: 146 --------KTKGLIQDLLPHGSVNSLTSLIFANALYFKGVWKQKFDTSKTKDYDFDLLNG 197
KT+G I D++P ++N LT L+ N +YFKG+WK KF T+ F +G
Sbjct: 217 AINKWVSNKTEGRITDVIPSEAINELTVLVLVNTIYFKGLWKSKFSPENTRKELFYKADG 276
Query: 198 KSVKVPFMTSKND-QFISSLDGFKVLGLP 225
+S M + ++ +G +VL LP
Sbjct: 277 ESCSASMMYQEGKFRYRRVAEGTQVLELP 305
>SPB9_HUMAN (P50453) Cytoplasmic antiproteinase 3 (CAP3) (CAP-3)
(Protease inhibitor 9) (Serpin B9)
Length = 376
Score = 81.3 bits (199), Expect = 2e-15
Identities = 47/164 (28%), Positives = 83/164 (49%), Gaps = 14/164 (8%)
Query: 42 NIVFSPLSLNTVLIMIATGSEGPTQNQLLSFLQSESTGDLKSLCSQVVSSVLSDGARAGG 101
N+ SP+S+++ L M+ G++G T Q+ L + D+ +++ V G +
Sbjct: 27 NVFCSPVSISSALAMVLLGAKGNTATQMAQALSLNTEEDIHRAFQSLLTEVNKAGTQY-- 84
Query: 102 PCLSYVNGVWVEKSLPLQPSFKQLMTTDFEATLSAVDFVNKAE-----------KKTKGL 150
L N ++ EK+ +FK+ + A L + F+ AE KKT+G
Sbjct: 85 -LLRTANRLFGEKTCQFLSTFKESCLQFYHAELKELSFIRAAEESRKHINTWVSKKTEGK 143
Query: 151 IQDLLPHGSVNSLTSLIFANALYFKGVWKQKFDTSKTKDYDFDL 194
I++LLP S+++ T L+ NA+YFKG W + FD + T++ F +
Sbjct: 144 IEELLPGSSIDAETRLVLVNAIYFKGKWNEPFDETYTREMPFKI 187
>PAI1_MUSVI (P50449) Plasminogen activator inhibitor-1 precursor
(PAI-1) (Endothelial plasminogen activator inhibitor)
(PAI)
Length = 400
Score = 80.9 bits (198), Expect = 3e-15
Identities = 60/189 (31%), Positives = 91/189 (47%), Gaps = 22/189 (11%)
Query: 36 QKLNEKNIVFSPLSLNTVLIMIATGSEGPTQNQLLSFL--QSESTG---DLKSLCSQVVS 90
Q ++N+VFSP L +VL M+ + G T+ Q+ + Q + G L+ L +++
Sbjct: 46 QASKDRNMVFSPYGLASVLAMLQLTTAGETRQQIQEAMRFQIDEKGMAPALRQLYKELMG 105
Query: 91 SVLSDGARAGGPCLSYVNGVWVEKSLPLQPSFKQLMTTDFEATLSAVDF--VNKA----- 143
D +S + ++V++ L L F F+ T+ VDF V +A
Sbjct: 106 PWNKDE-------ISTADAIFVQRDLKLVHGFMPYFFRLFQTTVKQVDFSEVERARFIIN 158
Query: 144 ---EKKTKGLIQDLLPHGSVNSLTSLIFANALYFKGVWKQKFDTSKTKDYDFDLLNGKSV 200
++ TKG+I DLL G+V+ LT L+ NALYF G WK F S T F +G +V
Sbjct: 159 DWVKRHTKGMIGDLLGRGTVDQLTRLMLVNALYFNGQWKTPFPKSGTHHRLFHKSDGSTV 218
Query: 201 KVPFMTSKN 209
VP M N
Sbjct: 219 SVPMMAQTN 227
>ANT3_BOVIN (P41361) Antithrombin-III (ATIII)
Length = 433
Score = 80.5 bits (197), Expect = 4e-15
Identities = 59/209 (28%), Positives = 97/209 (46%), Gaps = 17/209 (8%)
Query: 33 LSNQKLNEKNIVFSPLSLNTVLIMIATGSEGPTQNQLLSFLQ----SESTGDLKSLCSQV 88
L++ K N NI SPLS++T M G+ T QL+ + SE T D
Sbjct: 67 LADSKNNNDNIFLSPLSISTAFAMTKLGACNNTLTQLMEVFKFDTISEKTSDQIHFFFAK 126
Query: 89 VSSVLSDGARAGGPCLSYVNGVWVEKSLPLQPSFKQLMTTDFEATLSAVDFVNKAEK--- 145
++ L A +S N ++ +KS+ +++ + + A L +DF AE+
Sbjct: 127 LNCRLYRKANKSSELVS-ANRLFGDKSITFNETYQDISEVVYGAKLQPLDFKGNAEQSRL 185
Query: 146 --------KTKGLIQDLLPHGSVNSLTSLIFANALYFKGVWKQKFDTSKTKDYDFDLLNG 197
KT+G I D++P ++N T L+ N +YFKG+WK KF T+ F +G
Sbjct: 186 TINQWISNKTEGRITDVIPPQAINEFTVLVLVNTIYFKGLWKSKFSPENTRKELFYKADG 245
Query: 198 KSVKVPFMTSKND-QFISSLDGFKVLGLP 225
+S V M ++ ++ + +VL LP
Sbjct: 246 ESCSVLMMYQESKFRYRRVAESTQVLELP 274
>PAI1_MOUSE (P22777) Plasminogen activator inhibitor-1 precursor
(PAI-1) (Endothelial plasminogen activator inhibitor)
(PAI)
Length = 402
Score = 80.1 bits (196), Expect = 5e-15
Identities = 57/189 (30%), Positives = 92/189 (48%), Gaps = 22/189 (11%)
Query: 36 QKLNEKNIVFSPLSLNTVLIMIATGSEGPTQNQL---LSFLQSE--STGDLKSLCSQVVS 90
Q ++N+VFSP +++VL M+ + G T+ Q+ + F +E + L+ L +++
Sbjct: 48 QASKDRNVVFSPYGVSSVLAMLQMTTAGKTRRQIQDAMGFKVNEKGTAHALRQLSKELMG 107
Query: 91 SVLSDGARAGGPCLSYVNGVWVEKSLPLQPSFKQLMTTDFEATLSAVDF--VNKA----- 143
+ +S + ++V++ L L F F+ + VDF V +A
Sbjct: 108 PWNKNE-------ISTADAIFVQRDLELVQGFMPHFFKLFQTMVKQVDFSEVERARFIIN 160
Query: 144 ---EKKTKGLIQDLLPHGSVNSLTSLIFANALYFKGVWKQKFDTSKTKDYDFDLLNGKSV 200
E+ TKG+I DLL G+V+ LT L+ NALYF G WK F + T F +G +V
Sbjct: 161 DWVERHTKGMINDLLAKGAVDELTRLVLVNALYFSGQWKTPFLEASTHQRLFHKSDGSTV 220
Query: 201 KVPFMTSKN 209
VP M N
Sbjct: 221 SVPMMAQSN 229
>MASP_HUMAN (P36952) Maspin precursor (Protease inhibitor 5)
Length = 375
Score = 80.1 bits (196), Expect = 5e-15
Identities = 60/225 (26%), Positives = 101/225 (44%), Gaps = 18/225 (8%)
Query: 25 SLNITKHLLSNQKLNEKNIVFSPLSLNTVLIMIATGSEGPTQNQLLSFLQSESTGDLKSL 84
++++ K L + L N++FSP+ L+T L + G++G T N++ L E+ D+
Sbjct: 12 AVDLFKQLCEKEPLG--NVLFSPICLSTSLSLAQVGAKGDTANEIGQVLHFENVKDIPFG 69
Query: 85 CSQVVSSVLSDGARAGGPCLSYVNGVWVEKSLPLQPSFKQLMTTDFEATLSAVDFVNKAE 144
V S V + L + ++V+KSL L F + L VDF +K E
Sbjct: 70 FQTVTSDV---NKLSSFYSLKLIKRLYVDKSLNLSTEFISSTKRPYAKELETVDFKDKLE 126
Query: 145 KK-----------TKGLIQDLLPHGSVNSLTSLIFANALYFKGVWKQKFDTSKTKDYDFD 193
+ T G +++L SVN T ++ NA YF G W +KF S+TK+ F
Sbjct: 127 ETKGQINNSIKDLTDGHFENILADNSVNDQTKILVVNAAYFVGKWMKKFPESETKECPFR 186
Query: 194 LLNGKSVKVPFMTSKNDQFISSLDGF--KVLGLPINKAKMGVHSL 236
L + V M + + ++D K++ LP + + L
Sbjct: 187 LNKTDTKPVQMMNMEATFCMGNIDSINCKIIELPFQNKHLSMFIL 231
Database: sprot
Posted date: Nov 25, 2004 10:54 AM
Number of letters in database: 59,974,054
Number of sequences in database: 164,201
Lambda K H
0.317 0.133 0.375
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 27,643,312
Number of Sequences: 164201
Number of extensions: 1067714
Number of successful extensions: 3614
Number of sequences better than 10.0: 164
Number of HSP's better than 10.0 without gapping: 131
Number of HSP's successfully gapped in prelim test: 33
Number of HSP's that attempted gapping in prelim test: 3335
Number of HSP's gapped (non-prelim): 177
length of query: 249
length of database: 59,974,054
effective HSP length: 108
effective length of query: 141
effective length of database: 42,240,346
effective search space: 5955888786
effective search space used: 5955888786
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 64 (29.3 bits)
Medicago: description of AC122166.9