BLASTP 2.2.2 [Dec-14-2001]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= AC122166.8 + phase: 0 
         (404 letters)

Database: sprot 
           164,201 sequences; 59,974,054 total letters

Searching..................................................done

                                                                   Score     E
Sequences producing significant alignments:                        (bits)  Value

PRTZ_HORVU (P06293) Protein Z (Z4) (Major endosperm albumin)          328  1e-89
ILEU_PIG (P80229) Leukocyte elastase inhibitor (LEI) (Leucocyte ...   167  6e-41
PTI6_HUMAN (P35237) Placental thrombin inhibitor (Cytoplasmic an...   159  1e-38
PAI1_RAT (P20961) Plasminogen activator inhibitor-1 precursor (P...   157  3e-38
PAI1_PIG (P79335) Plasminogen activator inhibitor-1 precursor (P...   157  3e-38
ILEU_HORSE (P05619) Leukocyte elastase inhibitor (LEI)                155  1e-37
SB10_HUMAN (P48595) Bomapin (Protease inhibitor 10) (Serpin B10)      155  2e-37
PAI1_MOUSE (P22777) Plasminogen activator inhibitor-1 precursor ...   154  3e-37
PAI1_MUSVI (P50449) Plasminogen activator inhibitor-1 precursor ...   153  9e-37
SPB8_HUMAN (P50452) Cytoplasmic antiproteinase 2 (CAP2) (CAP-2) ...   152  1e-36
PAI2_MOUSE (P12388) Plasminogen activator inhibitor-2, macrophag...   152  1e-36
PTI6_MOUSE (Q60854) Placental thrombin inhibitor (Protease inhib...   150  6e-36
PAI1_HUMAN (P05121) Plasminogen activator inhibitor-1 precursor ...   150  7e-36
PAI1_BOVIN (P13909) Plasminogen activator inhibitor-1 precursor ...   150  7e-36
ILEU_HUMAN (P30740) Leukocyte elastase inhibitor (LEI) (Monocyte...   150  7e-36
SPB9_HUMAN (P50453) Cytoplasmic antiproteinase 3 (CAP3) (CAP-3) ...   149  1e-35
OVAY_CHICK (P01014) Gene Y protein (Ovalbumin-related)                149  1e-35
NEUS_RAT (Q9JLD2) Neuroserpin precursor (Protease inhibitor 17)       149  2e-35
ANT3_MOUSE (P32261) Antithrombin-III precursor (ATIII)                148  3e-35
NEUS_CHICK (Q90935) Neuroserpin precursor (Axonin-2)                  147  5e-35

>PRTZ_HORVU (P06293) Protein Z (Z4) (Major endosperm albumin)
          Length = 399

 Score =  328 bits (841), Expect = 1e-89
 Identities = 178/391 (45%), Positives = 254/391 (64%), Gaps = 11/391 (2%)

Query: 17  SLTNLTNVSLNITKHLLSNQKLNEKNVVFSPLSLNTVLIMITAGSEGPTQNQLLSFLQSE 76
           S+ + T  +L +   + SN +    NV FSPLSL+  L +ITAG+   T++QL++ L   
Sbjct: 12  SIAHQTRFALRLRSAISSNPERAAGNVAFSPLSLHVALSLITAGAAA-TRDQLVAILGDG 70

Query: 77  STGDLK---SLCSQLVSSVLSDGAPAGGPCLSHVNGVWVEQSLPLQPSFKQLMTTDFKAT 133
             GD K   +L  Q+V  VL++ +  GGP ++  NG++V+ SL L+PSF++L    +KA 
Sbjct: 71  GAGDAKELNALAEQVVQFVLANESSTGGPRIAFANGIFVDASLSLKPSFEELAVCQYKAK 130

Query: 134 LAAVDFINKADEVIKEVNLWANKETKGFINDLLPRGSVDSLTSLIFANALYFKGVWKRPF 193
             +VDF +K  E + +VN W  + T G I  +LP GSVD+ T LI  NALYFKG W + F
Sbjct: 131 TQSVDFQHKTLEAVGQVNSWVEQVTTGLIKQILPPGSVDNTTKLILGNALYFKGAWDQKF 190

Query: 194 DTSKTKDYDFDLLNGKSVKVPFMTSKNNQFISSFDGFKVLGLPYKQGNDKRAFSIYFFLP 253
           D S TK   F LL+G S++  FM+S   Q+ISS D  KVL LPY +G+DKR FS+Y  LP
Sbjct: 191 DESNTKCDSFHLLDGSSIQTQFMSSTKKQYISSSDNLKVLKLPYAKGHDKRQFSMYILLP 250

Query: 254 DEKDGLSALIDKVASDSEFLEQKLPRNQVKVGKFMIPRFNISFEIEASELLNKLGLTLPF 313
             +DGL +L  +++++ EF+E  +P+  V+VG+F +P+F IS++ EAS LL  LGL LPF
Sbjct: 251 GAQDGLWSLAKRLSTEPEFIENHIPKQTVEVGRFQLPKFKISYQFEASSLLRALGLQLPF 310

Query: 314 S-KGGLTKMVDSPISQELSVTSIFQKSFIELNEEGTIA-AATARGSTGGAAPFRLPPPPP 371
           S +  L++MVDS  SQ L ++ +F KSF+E+NEEGT A AAT       + P ++     
Sbjct: 311 SEEADLSEMVDS--SQGLEISHVFHKSFVEVNEEGTEAGAATVAMGVAMSMPLKV---DL 365

Query: 372 IDFVADHPFLFLIREEFSGTILFVGKVVNPL 402
           +DFVA+HPFLFLIRE+ +G ++FVG V NPL
Sbjct: 366 VDFVANHPFLFLIREDIAGVVVFVGHVTNPL 396


>ILEU_PIG (P80229) Leukocyte elastase inhibitor (LEI) (Leucocyte
           neutral proteinase inhibitor) (LNPI)
          Length = 378

 Score =  167 bits (422), Expect = 6e-41
 Identities = 127/387 (32%), Positives = 193/387 (49%), Gaps = 24/387 (6%)

Query: 22  TNVSLNITKHLLSNQKLNEKNVVFSPLSLNTVLIMITAGSEGPTQNQLLSFLQSESTGDL 81
           T  +L++ + L  N+     N+  SP S+++ L MI  G+ G T+ Q+   L  ++  D+
Sbjct: 9   TRFALDLFRAL--NESNPAGNIFISPFSISSALAMILLGTRGNTEAQMSKALHFDTVKDI 66

Query: 82  KSLCSQLVSSVLSDGAPAGGPCLSHVNGVWVEQSLPLQPSFKQLMTTDFKATLAAVDFIN 141
            S    L + +   GA      L   N ++ E++    P F       + A LA+VDF+ 
Sbjct: 67  HSRFQSLNADINKCGASY---ILKLANRLFGEKTYHFLPEFLASTQKTYGAELASVDFLR 123

Query: 142 KADEVIKEVNLWANKETKGFINDLLPRGSVDSLTSLIFANALYFKGVWKRPFDTSKTKDY 201
            ++E  K +N W  ++T+G I +LL  G VDS T L+  NA+YFKG W+  F T  TKD 
Sbjct: 124 ASEEARKAINEWVKEQTEGKIPELLASGVVDSATKLVLVNAIYFKGSWQEKFMTEATKDA 183

Query: 202 DFDLLNGKSVKVPFMTSKNNQFISSFDGFK--VLGLPYKQGNDKRAFSIYFFLPDEKDGL 259
            F L    S  V  M  K           K  VL LPY QG D    S+   LPD  +  
Sbjct: 184 PFRLNKKDSKTVKMMYQKKKFPFGYIKELKCRVLELPY-QGKD---LSMVILLPDSIEDE 239

Query: 260 SALIDKVASD---SEFLEQKLPRN-QVKVGKFMIPRFNISFEIEASELLNKLGLTLPF-S 314
           S  + K+       +  E   P N ++      +PRF +    + +  L +LG+   F S
Sbjct: 240 STGLRKIEQHLTLEKLNEWTKPDNLELLEVNVHLPRFRLEESYDLNAPLARLGVQDLFGS 299

Query: 315 KGGLTKMVDSPISQELSVTSIFQKSFIELNEEGTIAAATARGSTGGAAPFRLPPPPPIDF 374
           +  LT M +   +++L ++ +  K+F+E+NEEGT AAA    +T G A F +  P   DF
Sbjct: 300 RADLTGMSE---ARDLFISKVVHKAFVEVNEEGTEAAA----ATAGIAVFAMLMPEE-DF 351

Query: 375 VADHPFLFLIREEFSGTILFVGKVVNP 401
           +ADHPF+F IR   S  ILF+G++ +P
Sbjct: 352 IADHPFIFFIRHNPSSNILFLGRLSSP 378


>PTI6_HUMAN (P35237) Placental thrombin inhibitor (Cytoplasmic
           antiproteinase) (CAP) (Protease inhibitor 6) (PI-6)
          Length = 376

 Score =  159 bits (402), Expect = 1e-38
 Identities = 125/385 (32%), Positives = 194/385 (49%), Gaps = 28/385 (7%)

Query: 25  SLNITKHLLSNQKLNEKNVVFSPLSLNTVLIMITAGSEGPT---QNQLLSFLQSESTGDL 81
           +LN+ K L    K N KNV FSP+S++  L M+  G++G T     Q+LSF +S   GD+
Sbjct: 12  ALNLLKTL---GKDNSKNVFFSPMSMSCALAMVYMGAKGNTAAQMAQILSFNKSGGGGDI 68

Query: 82  KSLCSQLVSSVLSDGAPAGGPCLSHVNGVWVEQSLPLQPSFKQLMTTDFKATLAAVDFIN 141
                 L++ V   G       L   N ++ E+S     SF+      ++A +  +DFI+
Sbjct: 69  HQGFQSLLTEVNKTGTQY---LLRVANRLFGEKSCDFLSSFRDSCQKFYQAEMEELDFIS 125

Query: 142 KADEVIKEVNLWANKETKGFINDLLPRGSVDSLTSLIFANALYFKGVWKRPFDTSKTKDY 201
             ++  K +N W  ++T+G I +LL  GSVD LT L+  NA+YF+G W   FD   T++ 
Sbjct: 126 AVEKSRKHINTWVAEKTEGKIAELLSPGSVDPLTRLVLVNAVYFRGNWDEQFDKENTEER 185

Query: 202 DFDLLNGKSVKVPFMTSKNNQFISSFDG---FKVLGLPYKQGNDKRAFSIYFFLPDEKDG 258
            F +   +   V  M  K + F  ++ G    ++L LPY      +  ++   LPDE   
Sbjct: 186 LFKVSKNEEKPVQMM-FKQSTFKKTYIGEIFTQILVLPYV----GKELNMIIMLPDETTD 240

Query: 259 LSALIDKVASDSEFLE-QKLPRNQVKVGKFMIPRFNISFEIEASELLNKLGLTLPFSKGG 317
           L   ++K  +  +F+E  +L     +  +  +PRF +    +   +L  LG+T  F  G 
Sbjct: 241 LRT-VEKELTYEKFVEWTRLDMMDEEEVEVSLPRFKLEESYDMESVLRNLGMTDAFELG- 298

Query: 318 LTKMVDSPISQ-ELSVTSIFQKSFIELNEEGTIAAATARGSTGGAAPFRLPPPPPIDFVA 376
             K   S +SQ +LS++ +  KSF+E+NEEGT AAA    +T      R     P  F A
Sbjct: 299 --KADFSGMSQTDLSLSKVVHKSFVEVNEEGTEAAA----ATAAIMMMRCARFVP-RFCA 351

Query: 377 DHPFLFLIREEFSGTILFVGKVVNP 401
           DHPFLF I+   +  ILF G+  +P
Sbjct: 352 DHPFLFFIQHSKTNGILFCGRFSSP 376


>PAI1_RAT (P20961) Plasminogen activator inhibitor-1 precursor
           (PAI-1) (Endothelial plasminogen activator inhibitor)
           (PAI)
          Length = 402

 Score =  157 bits (398), Expect = 3e-38
 Identities = 125/395 (31%), Positives = 208/395 (52%), Gaps = 43/395 (10%)

Query: 22  TNVSLNITKHLLSNQKLNEKNVVFSPLSLNTVLIMITAGSEGPTQNQL---LSFLQSE-- 76
           TN  + + +H++   K  ++NVVFSP  +++VL M+   + G T+ Q+   + F  SE  
Sbjct: 36  TNFGVKVFQHVVQASK--DRNVVFSPYGVSSVLAMLQLTTAGKTRQQIQDAMGFNISERG 93

Query: 77  STGDLKSLCSQLVSSVLSDGAPAGGPCLSHVNGVWVEQSLPLQPSFKQLMTTDFKATLAA 136
           +   L+ L  +L+ S   +        +S  + ++V++ L L   F       F+ T+  
Sbjct: 94  TAPALRKLSKELMGSWNKNE-------ISTADAIFVQRDLELVQGFMPHFFKLFRTTVKQ 146

Query: 137 VDFINKADEVIKEVNLWANKETKGFINDLLPRGSVDSLTSLIFANALYFKGVWKRPFDTS 196
           VDF ++ +     +N W  + TKG I+DLL +G+V+ LT L+  NALYF G WK PF  +
Sbjct: 147 VDF-SEVERARFIINDWVERHTKGMISDLLAKGAVNELTRLVLVNALYFNGQWKTPFLEA 205

Query: 197 KTKDYDFDLLNGKSVKVPFMTSKNNQF----ISSFDG--FKVLGLPYKQGNDKRAFSIYF 250
            T    F   +G ++ VP M ++NN+F     ++ DG  + +L LPY         S++ 
Sbjct: 206 STHQRLFHKSDGSTISVPMM-AQNNKFNYTEFTTPDGHEYDILELPY----HGETLSMFI 260

Query: 251 FLPDEKD-GLSALIDKVASDSEFLEQKLPRNQVKVGKFMI-PRFNISFEIEASELLNKLG 308
             P EKD  LSA+ + +  D+E + Q    N  ++ + +I P+F++  E++    L KLG
Sbjct: 261 AAPFEKDVPLSAITNIL--DAELIRQ-WKSNMTRLPRLLILPKFSLETEVDLRGPLEKLG 317

Query: 309 LTLPFS--KGGLTKMVDSPISQELSVTSIFQKSFIELNEEGTIAAATARGSTGGAAPFRL 366
           +T  FS  +   T + D    ++LSV    QK  IE+NE GT+A++    ST      R+
Sbjct: 318 MTDIFSSTQADFTSLSD---QEQLSVAQALQKVKIEVNESGTVASS----STAILVSARM 370

Query: 367 PPPPPIDFVADHPFLFLIREEFSGTILFVGKVVNP 401
               P + V D  FLF++R   + TILF+G+++ P
Sbjct: 371 ---APTEMVLDRSFLFVVRHNPTETILFMGQLMEP 402


>PAI1_PIG (P79335) Plasminogen activator inhibitor-1 precursor
           (PAI-1) (Endothelial plasminogen activator inhibitor)
           (PAI)
          Length = 402

 Score =  157 bits (398), Expect = 3e-38
 Identities = 122/377 (32%), Positives = 192/377 (50%), Gaps = 33/377 (8%)

Query: 36  QKLNEKNVVFSPLSLNTVLIMITAGSEGPTQNQLLSFLQS--ESTGDLKSLCSQLVSSVL 93
           Q   ++NVVFSP  + +VL M+   + G TQ Q+   +Q   E  G   +L  QL   ++
Sbjct: 48  QASKDRNVVFSPYGVASVLAMLQLTTAGDTQQQIQEAMQFKIEEKGMAPAL-RQLYKELM 106

Query: 94  SDGAPAGGPCLSHVNGVWVEQSLPLQPSFKQLMTTDFKATLAAVDFINKADEVIKEVNLW 153
               P     +S  + ++V++ L L   F       F+ T+  VDF ++ D     +N W
Sbjct: 107 G---PWNKDEISTADAIFVQRDLKLVQGFMPYFFRLFRTTVKQVDF-SEMDRARFIINDW 162

Query: 154 ANKETKGFINDLLPRGSVDSLTSLIFANALYFKGVWKRPFDTSKTKDYDFDLLNGKSVKV 213
             + TKG INDLL +G+VD LT L+  NALYF G WK PF    T    F   +G +V V
Sbjct: 163 VKRHTKGMINDLLGQGAVDQLTRLVLVNALYFNGQWKTPFPEKSTHHRLFHKSDGSTVSV 222

Query: 214 PFMTSKNNQFISSF---DG--FKVLGLPYKQGNDKRAFSIYFFLPDEKD-GLSALIDKVA 267
           P M   N    + F   DG  + +L LPY  GN     S++   P EK+  LSAL   + 
Sbjct: 223 PMMAQTNKFNYTEFSTPDGHYYDILELPY-HGN---TLSMFIAAPYEKEVPLSALTSIL- 277

Query: 268 SDSEFLEQKLPRNQVKVGKFMI-PRFNISFEIEASELLNKLGLTLPF--SKGGLTKMVDS 324
            D++ + Q    N  ++ + ++ P+F++  E++    L  LG+T  F  ++   + + D 
Sbjct: 278 -DAQLISQ-WKGNMTRLTRLLVLPKFSLESEVDLRRPLENLGMTDMFRPNQADFSSLSDQ 335

Query: 325 PISQELSVTSIFQKSFIELNEEGTIAAATARGSTGGAAPFRLPPPPPIDFVADHPFLFLI 384
            +   L ++   QK  IE+NE GT+A++    ST      R+ P    + + D PFLF++
Sbjct: 336 EL---LYMSQALQKVKIEVNESGTVASS----STAIIVSARMAPE---EIIMDRPFLFVV 385

Query: 385 REEFSGTILFVGKVVNP 401
           R   +GT+LF+G+V+ P
Sbjct: 386 RHNPTGTVLFMGQVMEP 402


>ILEU_HORSE (P05619) Leukocyte elastase inhibitor (LEI)
          Length = 379

 Score =  155 bits (393), Expect = 1e-37
 Identities = 117/367 (31%), Positives = 182/367 (48%), Gaps = 21/367 (5%)

Query: 42  NVVFSPLSLNTVLIMITAGSEGPTQNQLLSFLQSESTGDLKSLCSQLVSSVLSDGAPAGG 101
           N+  SPLS+++ L MI  G+ G T  Q+   L  ++  D+ S    L + +   GAP   
Sbjct: 27  NIFISPLSISSALAMIFLGTRGNTAAQVSKALYFDTVEDIHSRFQSLNADINKPGAPY-- 84

Query: 102 PCLSHVNGVWVEQSLPLQPSFKQLMTTDFKATLAAVDFINKADEVIKEVNLWANKETKGF 161
             L   N ++ E++      F       + A LA+VDF    ++  KE+N W   +T+G 
Sbjct: 85  -ILKLANRLYGEKTYNFLADFLASTQKMYGAELASVDFQQAPEDARKEINEWVKGQTEGK 143

Query: 162 INDLLPRGSVDSLTSLIFANALYFKGVWKRPFDTSKTKDYDFDLLNGKSVKVPFMTSKNN 221
           I +LL +G VD++T L+  NA+YFKG W+  F    T+D  F  LN K  K   M  +  
Sbjct: 144 IPELLVKGMVDNMTKLVLVNAIYFKGNWQEKFMKEATRDAPF-RLNKKDTKTVKMMYQKK 202

Query: 222 QFISSFD---GFKVLGLPYKQGNDKRAFSIYFFLPDEKDGLSALIDKVASD---SEFLEQ 275
           +F  ++      +VL LPY QG +    S+   LPD+ +  S  ++K+       +  E 
Sbjct: 203 KFPYNYIEDLKCRVLELPY-QGKE---LSMIILLPDDIEDESTGLEKIEKQLTLEKLREW 258

Query: 276 KLPRN-QVKVGKFMIPRFNISFEIEASELLNKLGLTLPFSKGGLTKMVDSPISQELSVTS 334
             P N  +      +PRF +    + +  L +LG+   F++ G   +     +++L V+ 
Sbjct: 259 TKPENLYLAEVNVHLPRFKLEESYDLTSHLARLGVQDLFNR-GKADLSGMSGARDLFVSK 317

Query: 335 IFQKSFIELNEEGTIAAATARGSTGGAAPFRLPPPPPIDFVADHPFLFLIREEFSGTILF 394
           I  KSF++LNEEGT AAA   G+   A        P  +F ADHPF+F IR   S  ILF
Sbjct: 318 IIHKSFVDLNEEGTEAAAATAGTIMLAMLM-----PEENFNADHPFIFFIRHNPSANILF 372

Query: 395 VGKVVNP 401
           +G+  +P
Sbjct: 373 LGRFSSP 379


>SB10_HUMAN (P48595) Bomapin (Protease inhibitor 10) (Serpin B10)
          Length = 397

 Score =  155 bits (391), Expect = 2e-37
 Identities = 112/407 (27%), Positives = 193/407 (46%), Gaps = 39/407 (9%)

Query: 19  TNLTNVSLNITKHLLSNQKLNEKNVVFSPLSLNTVLIMITAGSEGPTQNQLLSFLQSE-- 76
           T++   +L ++K L  + +   KN+ FS  S++T L ++  G++G T  Q+   LQ    
Sbjct: 6   TSINQFALELSKKLAESAQ--GKNIFFSSWSISTSLTIVYLGAKGTTAAQMAQVLQFNRD 63

Query: 77  --------------------STGDLKSLCSQLVSSVLSDGAPAGGPCLSHVNGVWVEQSL 116
                               ++ ++ S    L+S +L    P     L   N ++ E++ 
Sbjct: 64  QGVKCDPESEKKRKMEFNLSNSEEIHSDFQTLISEILK---PNDDYLLKTANAIYGEKTY 120

Query: 117 PLQPSFKQLMTTDFKATLAAVDFINKADEVIKEVNLWANKETKGFINDLLPRGSVDSLTS 176
                + + M T F A    V+F+  +D++ K++N W  ++T+G I +LLP  SVDS T 
Sbjct: 121 AFHNKYLEDMKTYFGAEPQPVNFVEASDQIRKDINSWVERQTEGKIQNLLPDDSVDSTTR 180

Query: 177 LIFANALYFKGVWKRPFDTSKTKDYDFDLLNGKSVKVPFMTSKNNQFISSFDGFKVLGLP 236
           +I  NALYFKG+W+  F    T +  F +    S  V  M  K    I   +  K +GL 
Sbjct: 181 MILVNALYFKGIWEHQFLVQNTTEKPFRINETTSKPVQMMFMKKKLHIFHIEKPKAVGLQ 240

Query: 237 --YKQGNDKRAFSIYFFLPDEKDGLSALIDKVASDSEFLEQKLPRNQVKVGKFMIPRFNI 294
             YK     R  S+   LP++ +GL  L   +  +           ++   +  +P+F +
Sbjct: 241 LYYK----SRDLSLLILLPEDINGLEQLEKAITYEKLNEWTSADMMELYEVQLHLPKFKL 296

Query: 295 SFEIEASELLNKLGLTLPFSKGGLTKMVDSPISQELSVTSIFQKSFIELNEEGTIAAATA 354
               +    L+ +G++  FS+           ++ L ++++F K+F+E+NE+GT AAA  
Sbjct: 297 EDSYDLKSTLSSMGMSDAFSQ-SKADFSGMSSARNLFLSNVFHKAFVEINEQGTEAAA-- 353

Query: 355 RGSTGGAAPFRLPPPPPIDFVADHPFLFLIREEFSGTILFVGKVVNP 401
              +G     R+   P I+F A+HPFLF IR   + TILF G++ +P
Sbjct: 354 --GSGSEIDIRI-RVPSIEFNANHPFLFFIRHNKTNTILFYGRLCSP 397


>PAI1_MOUSE (P22777) Plasminogen activator inhibitor-1 precursor
           (PAI-1) (Endothelial plasminogen activator inhibitor)
           (PAI)
          Length = 402

 Score =  154 bits (390), Expect = 3e-37
 Identities = 122/378 (32%), Positives = 191/378 (50%), Gaps = 35/378 (9%)

Query: 36  QKLNEKNVVFSPLSLNTVLIMITAGSEGPTQNQL---LSFLQSE--STGDLKSLCSQLVS 90
           Q   ++NVVFSP  +++VL M+   + G T+ Q+   + F  +E  +   L+ L  +L+ 
Sbjct: 48  QASKDRNVVFSPYGVSSVLAMLQMTTAGKTRRQIQDAMGFKVNEKGTAHALRQLSKELMG 107

Query: 91  SVLSDGAPAGGPCLSHVNGVWVEQSLPLQPSFKQLMTTDFKATLAAVDFINKADEVIKEV 150
                  P     +S  + ++V++ L L   F       F+  +  VDF ++ +     +
Sbjct: 108 -------PWNKNEISTADAIFVQRDLELVQGFMPHFFKLFQTMVKQVDF-SEVERARFII 159

Query: 151 NLWANKETKGFINDLLPRGSVDSLTSLIFANALYFKGVWKRPFDTSKTKDYDFDLLNGKS 210
           N W  + TKG INDLL +G+VD LT L+  NALYF G WK PF  + T    F   +G +
Sbjct: 160 NDWVERHTKGMINDLLAKGAVDELTRLVLVNALYFSGQWKTPFLEASTHQRLFHKSDGST 219

Query: 211 VKVPFMTSKNNQFISSF---DG--FKVLGLPYKQGNDKRAFSIYFFLPDEKD-GLSALID 264
           V VP M   N    + F   DG  + V+ LPY+    +   S++   P EKD  LSAL +
Sbjct: 220 VSVPMMAQSNKFNYTEFTTPDGLEYDVVELPYQ----RDTLSMFIAAPFEKDVHLSALTN 275

Query: 265 KVASDSEFLEQKLPRNQVKVGKFMI-PRFNISFEIEASELLNKLGLTLPFSKGGLTKMVD 323
            +  D+E + Q    N  ++ + +I P+F++  E++    L KLG+   FS   L     
Sbjct: 276 IL--DAELIRQ-WKGNMTRLPRLLILPKFSLETEVDLRGPLEKLGMPDMFS-ATLADFTS 331

Query: 324 SPISQELSVTSIFQKSFIELNEEGTIAAATARGSTGGAAPFRLPPPPPIDFVADHPFLFL 383
               ++LSV    QK  IE+NE GT+A++    ST      R+    P + V D  FLF+
Sbjct: 332 LSDQEQLSVAQALQKVRIEVNESGTVASS----STAFVISARM---APTEMVIDRSFLFV 384

Query: 384 IREEFSGTILFVGKVVNP 401
           +R   + TILF+G+V+ P
Sbjct: 385 VRHNPTETILFMGQVMEP 402


>PAI1_MUSVI (P50449) Plasminogen activator inhibitor-1 precursor
           (PAI-1) (Endothelial plasminogen activator inhibitor)
           (PAI)
          Length = 400

 Score =  153 bits (386), Expect = 9e-37
 Identities = 115/374 (30%), Positives = 183/374 (48%), Gaps = 27/374 (7%)

Query: 36  QKLNEKNVVFSPLSLNTVLIMITAGSEGPTQNQLLSFLQSESTGDLKSLCSQLVSSVLSD 95
           Q   ++N+VFSP  L +VL M+   + G T+ Q+   ++ +   D K +   L       
Sbjct: 46  QASKDRNMVFSPYGLASVLAMLQLTTAGETRQQIQEAMRFQI--DEKGMAPALRQLYKEL 103

Query: 96  GAPAGGPCLSHVNGVWVEQSLPLQPSFKQLMTTDFKATLAAVDFINKADEVIKEVNLWAN 155
             P     +S  + ++V++ L L   F       F+ T+  VDF ++ +     +N W  
Sbjct: 104 MGPWNKDEISTADAIFVQRDLKLVHGFMPYFFRLFQTTVKQVDF-SEVERARFIINDWVK 162

Query: 156 KETKGFINDLLPRGSVDSLTSLIFANALYFKGVWKRPFDTSKTKDYDFDLLNGKSVKVPF 215
           + TKG I DLL RG+VD LT L+  NALYF G WK PF  S T    F   +G +V VP 
Sbjct: 163 RHTKGMIGDLLGRGTVDQLTRLMLVNALYFNGQWKTPFPKSGTHHRLFHKSDGSTVSVPM 222

Query: 216 MTSKNNQFISSFDG-----FKVLGLPYKQGNDKRAFSIYFFLPDEKD-GLSALIDKVASD 269
           M   N    + F       + +L LPY         S++   P EKD  LSAL + +  D
Sbjct: 223 MAQTNKFNYTEFSTPEGRYYDILELPYHGD----TLSMFIAAPYEKDVPLSALTNIL--D 276

Query: 270 SEFLEQKLPRNQVKVGKFMIPRFNISFEIEASELLNKLGLTLPF--SKGGLTKMVDSPIS 327
           ++ + Q       ++   ++P+F++  E+     L  LG+T  F  ++   + + D    
Sbjct: 277 AQLISQWKGNMTRRLRLLVLPKFSLESEVNLRGPLENLGMTDMFRPNQADFSSLSD---Q 333

Query: 328 QELSVTSIFQKSFIELNEEGTIAAATARGSTGGAAPFRLPPPPPIDFVADHPFLFLIREE 387
           + L V+   QK  IE+NE GT+A++    ST      R+ P    + + D PFLF++R  
Sbjct: 334 EALYVSQALQKVKIEVNESGTVASS----STAIIVSARMAPE---EIIMDRPFLFVVRHN 386

Query: 388 FSGTILFVGKVVNP 401
            +GT+LF+G+V+ P
Sbjct: 387 PTGTVLFMGQVMEP 400


>SPB8_HUMAN (P50452) Cytoplasmic antiproteinase 2 (CAP2) (CAP-2)
           (Protease inhibitor 8) (Serpin B8)
          Length = 374

 Score =  152 bits (385), Expect = 1e-36
 Identities = 117/386 (30%), Positives = 189/386 (48%), Gaps = 26/386 (6%)

Query: 23  NVSLNITKHLLSNQKLNEKNVVFSPLSLNTVLIMITAGSEGPTQNQLLSFLQSESTGDLK 82
           N +  I+   +  ++ N +NV FSP+S+++ L M+  G++G T  Q+   L     GD+ 
Sbjct: 8   NGTFAISLFKILGEEDNSRNVFFSPMSISSALAMVFMGAKGSTAAQMSQALCLYKDGDIH 67

Query: 83  SLCSQLVSSVLSDGAPAGGPCLSHVNGVWVEQSLPLQPSFKQLMTTDFKATLAAVDFINK 142
                L+S V   G       L   N ++ E++    P FK+     ++A L  + F   
Sbjct: 68  RGFQSLLSEVNRTGTQY---LLRTANRLFGEKTCDFLPDFKEYCQKFYQAELEELSFAED 124

Query: 143 ADEVIKEVNLWANKETKGFINDLLPRGSVDSLTSLIFANALYFKGVWKRPFDTSKTKDYD 202
            +E  K +N W  ++T+G I+++L  G+VD LT L+  NA+YFKG W   FD   T+   
Sbjct: 125 TEECRKHINDWVAEKTEGKISEVLDAGTVDPLTKLVLVNAIYFKGKWNEQFDRKYTRGML 184

Query: 203 FDL-LNGKSVKVPFMTSKNNQFISSFDGFKVLGLPYKQGNDKRAFSIYFFLPDEKDGLSA 261
           F      K+V++ F  +K     +     +VL LPY +       S+   LPD+   L A
Sbjct: 185 FKTNEEKKTVQMMFKEAKFKMGYADEVHTQVLELPYVE----EELSMVILLPDDNTDL-A 239

Query: 262 LIDKVASDSEFL----EQKLPRNQVKVGKFMIPRFNISFEIEASELLNKLGLTLPFSKGG 317
           +++K  +  +F      +KL +++V+V    +PR  +    +    L +LG+   F +  
Sbjct: 240 VVEKALTYEKFKAWTNSEKLTKSKVQV---FLPRLKLEESYDLEPFLRRLGMIDAFDE-- 294

Query: 318 LTKMVDSPISQELSV--TSIFQKSFIELNEEGTIAAATARGSTGGAAPFRLPPPPPIDFV 375
             K   S +S E +V  + +  K F+E+NEEGT AAA A      +   R+ P     F 
Sbjct: 295 -AKADFSGMSTEKNVPLSKVAHKCFVEVNEEGTEAAA-ATAVVRNSRCSRMEP----RFC 348

Query: 376 ADHPFLFLIREEFSGTILFVGKVVNP 401
           ADHPFLF IR   +  ILF G+  +P
Sbjct: 349 ADHPFLFFIRRHKTNCILFCGRFSSP 374


>PAI2_MOUSE (P12388) Plasminogen activator inhibitor-2, macrophage
           (PAI-2)
          Length = 415

 Score =  152 bits (384), Expect = 1e-36
 Identities = 122/429 (28%), Positives = 195/429 (45%), Gaps = 71/429 (16%)

Query: 22  TNVSLNITKHLLSNQKLNEKNVVFSPLSLNTVLIMITAGSEGPTQNQLLSFLQSESTGD- 80
           T  +LN+ K +  +   + +N+  SP S+++ L ++  G+ G T+ Q+   LQ    G  
Sbjct: 9   TMFALNLLKQIEKSN--STQNIFISPWSISSTLAIVLLGAGGNTEQQMAKVLQFNEIGSY 66

Query: 81  ----------------------------LKSLCSQLVSSVLSD-----GAPAGGPCLSHV 107
                                       L++     + S  S        P G   L   
Sbjct: 67  GITTRNPENFSGCDFAQQIQKENYPSAILQAQAGDKIHSAFSSLSSTINTPQGDYLLESA 126

Query: 108 NGVWVEQSLPLQPSFKQLMTTDFKATLAAVDFINKADEVIKEVNLWANKETKGFINDLLP 167
           N ++ E+S   +  + QL    +     AVDF+  A+E  +++N W   +TKG I +LLP
Sbjct: 127 NKLFGEKSARFKEEYIQLSKKYYSTEPEAVDFLECAEEAREKINSWVKTQTKGEIPNLLP 186

Query: 168 RGSVDSLTSLIFANALYFKGVWKRPFDTSKTKDYDFDLLNGKSVKVPFMTSKNNQFISSF 227
            GSVD  T ++  NA+YFKG WK PF+      Y F + + +S+ V  M       I   
Sbjct: 187 EGSVDEDTKMVLVNAVYFKGKWKTPFEKKLNGLYPFRVNSHESIPVQMMFLHAKLNIGYI 246

Query: 228 DGFK--VLGLPYKQGNDKRAFSIYFFLPDEKDGLSALIDKVASDSEFL-------EQKLP 278
              K  +L LP+  GN     S+   LPDE +  S  ++ + S+  F        +  L 
Sbjct: 247 KDLKTQILELPH-TGN----ISMLLLLPDEIEDASTGLELLESEINFANFNKWISKDTLD 301

Query: 279 RNQVKVGKFMIPRFNISFEIEASELLNKLGLTLPFSKGGLTKMVDSPISQ--ELSVTSIF 336
            + V V    IP+F ++   E   +L  +G+   F+KG   K   S +S+  +L ++ +F
Sbjct: 302 EDDVVV---YIPKFKLAQSYELKSILQSMGMEDAFNKG---KANFSGMSERNDLFLSEVF 355

Query: 337 QKSFIELNEEGTIAA----ATARGSTGGAAPFRLPPPPPIDFVADHPFLFLIREEFSGTI 392
            ++ +++ EEGT+AA    A   G TG   P          FVADHPFLF I ++ + TI
Sbjct: 356 HQASVDVTEEGTVAAGGTGAVMTGRTGHGGP---------QFVADHPFLFFIMDKITHTI 406

Query: 393 LFVGKVVNP 401
           LFVG+  +P
Sbjct: 407 LFVGRFSSP 415


>PTI6_MOUSE (Q60854) Placental thrombin inhibitor (Protease
           inhibitor 6) (PI-6)
          Length = 378

 Score =  150 bits (379), Expect = 6e-36
 Identities = 118/389 (30%), Positives = 191/389 (48%), Gaps = 34/389 (8%)

Query: 25  SLNITKHLLSNQKLNEKNVVFSPLSLNTVLIMITAGSEGPTQNQLLSFLQSEST-----G 79
           +LN+ K L  +   + KNV  SP+S+++ L M+  G++G T +Q+   L  +       G
Sbjct: 12  ALNLLKILGED---SSKNVFLSPMSISSALAMVFMGAKGTTASQMAQALALDKCSGNGGG 68

Query: 80  DLKSLCSQLVSSVLSDGAPAGGPCLSHVNGVWVEQSLPLQPSFKQLMTTDFKATLAAVDF 139
           D+      L++ V   G       L   N ++ +++  L  SFK      ++A L  +DF
Sbjct: 69  DVHQGFQSLLTEVNKTGTQY---LLRTANRLFGDKTCDLLASFKDSCLKFYEAELEELDF 125

Query: 140 INKADEVIKEVNLWANKETKGFINDLLPRGSVDSLTSLIFANALYFKGVWKRPFDTSKTK 199
               +E  + +N W  K+T+  I ++L  G+V+S TSL+  NA+YFKG W++ F+   T+
Sbjct: 126 QGATEESRQHINTWVAKKTEDKIKEVLSPGTVNSDTSLVLVNAIYFKGNWEKQFNKEHTR 185

Query: 200 DYDFDLLNGKSVKVPFMTSKNNQFISSFDG---FKVLGLPYKQGNDKRAFSIYFFLPDEK 256
           +  F +   +   V  M  K+  F  ++ G    K+L LPY         ++   LPDE 
Sbjct: 186 EMPFKVSKNEEKPVQMMFKKST-FKMTYIGEIFTKILLLPYVSSE----LNMIIMLPDEH 240

Query: 257 DGLSALIDKVASDSEFLE----QKLPRNQVKVGKFMIPRFNISFEIEASELLNKLGLTLP 312
             LS  ++K  +  +F+E     K+   +V+V    +P+F +      ++ L KLG+T  
Sbjct: 241 VELST-VEKEVTYEKFIEWTRLDKMDEEEVEV---FLPKFKLEENYNMNDALYKLGMTDA 296

Query: 313 FSKGGLTKMVDSPISQELSVTSIFQKSFIELNEEGTIAAATARGSTGGAAPFRLPPPPPI 372
           F  GG          Q L ++ +  K+F+E+NEEGT AAA    +T G    R     P 
Sbjct: 297 F--GGRADFSGMSSKQGLFLSKVVHKAFVEVNEEGTEAAA----ATAGMMTVRCMRFTP- 349

Query: 373 DFVADHPFLFLIREEFSGTILFVGKVVNP 401
            F ADHPFLF I    +  ILF G+  +P
Sbjct: 350 RFCADHPFLFFIHHVKTNGILFCGRFSSP 378


>PAI1_HUMAN (P05121) Plasminogen activator inhibitor-1 precursor
           (PAI-1) (Endothelial plasminogen activator inhibitor)
           (PAI)
          Length = 402

 Score =  150 bits (378), Expect = 7e-36
 Identities = 116/375 (30%), Positives = 186/375 (48%), Gaps = 29/375 (7%)

Query: 36  QKLNEKNVVFSPLSLNTVLIMITAGSEGPTQNQLLSFLQSESTGDLKSLCSQLVSSVLSD 95
           Q   ++NVVFSP  + +VL M+   + G TQ Q+ + +  +   D K +   L       
Sbjct: 48  QASKDRNVVFSPYGVASVLAMLQLTTGGETQQQIQAAMGFKI--DDKGMAPALRHLYKEL 105

Query: 96  GAPAGGPCLSHVNGVWVEQSLPLQPSFKQLMTTDFKATLAAVDFINKADEVIKEVNLWAN 155
             P     +S  + ++V++ L L   F       F++T+  VDF ++ +     +N W  
Sbjct: 106 MGPWNKDEISTTDAIFVQRDLKLVQGFMPHFFRLFRSTVKQVDF-SEVERARFIINDWVK 164

Query: 156 KETKGFINDLLPRGSVDSLTSLIFANALYFKGVWKRPFDTSKTKDYDFDLLNGKSVKVPF 215
             TKG I++LL +G+VD LT L+  NALYF G WK PF  S T    F   +G +V VP 
Sbjct: 165 THTKGMISNLLGKGAVDQLTRLVLVNALYFNGQWKTPFPDSSTHRRLFHKSDGSTVSVPM 224

Query: 216 MTSKNNQFISSF---DG--FKVLGLPYKQGNDKRAFSIYFFLPDEKD-GLSALIDKVASD 269
           M   N    + F   DG  + +L LPY         S++   P EK+  LSAL + +++ 
Sbjct: 225 MAQTNKFNYTEFTTPDGHYYDILELPYHGD----TLSMFIAAPYEKEVPLSALTNILSAQ 280

Query: 270 SEFLEQKLPRNQVKVGKFMI-PRFNISFEIEASELLNKLGLTLPFS--KGGLTKMVDSPI 326
              L      N  ++ + ++ P+F++  E++  + L  LG+T  F   +   T + D   
Sbjct: 281 ---LISHWKGNMTRLPRLLVLPKFSLETEVDLRKPLENLGMTDMFRQFQADFTSLSD--- 334

Query: 327 SQELSVTSIFQKSFIELNEEGTIAAATARGSTGGAAPFRLPPPPPIDFVADHPFLFLIRE 386
            + L V    QK  IE+NE GT+A++    ST      R+ P    + + D PFLF++R 
Sbjct: 335 QEPLHVAQALQKVKIEVNESGTVASS----STAVIVSARMAPE---EIIMDRPFLFVVRH 387

Query: 387 EFSGTILFVGKVVNP 401
             +GT+LF+G+V+ P
Sbjct: 388 NPTGTVLFMGQVMEP 402


>PAI1_BOVIN (P13909) Plasminogen activator inhibitor-1 precursor
           (PAI-1) (Endothelial plasminogen activator inhibitor)
           (PAI)
          Length = 402

 Score =  150 bits (378), Expect = 7e-36
 Identities = 119/371 (32%), Positives = 185/371 (49%), Gaps = 29/371 (7%)

Query: 40  EKNVVFSPLSLNTVLIMITAGSEGPTQNQLLSFLQSESTGDLKSLCSQLVSSVLSDGAPA 99
           ++NVVFSP  + +VL M+   + G T+ Q+   +Q +   + K +             P 
Sbjct: 52  DRNVVFSPYGVASVLAMLQLTTGGETRQQIQEAMQFKI--EEKGMAPAFHRLYKELMGPW 109

Query: 100 GGPCLSHVNGVWVEQSLPLQPSFKQLMTTDFKATLAAVDFINKADEVIKEVNLWANKETK 159
               +S  + ++V++ L L   F       F+ T+  VDF ++ +     VN W  + TK
Sbjct: 110 NKDEISTADAIFVQRDLELVHGFMPNFFRLFRTTVKQVDF-SEVERARFIVNDWVKRHTK 168

Query: 160 GFINDLLPRGSVDSLTSLIFANALYFKGVWKRPFDTSKTKDYDFDLLNGKSVKVPFMTSK 219
           G I+DLL  G+VD LT L+  NALYF G WK PF  S T    F   +G ++ VP M   
Sbjct: 169 GMISDLLGEGAVDQLTRLVLVNALYFNGQWKMPFPESNTHHRLFHKSDGSTISVPMMAQT 228

Query: 220 NNQFISSF---DG--FKVLGLPYKQGNDKRAFSIYFFLPDEKD-GLSALIDKVASDSEFL 273
           N    + F   DG  + +L LPY  GN     S+    P EK+  LSAL   +  D+E +
Sbjct: 229 NKFNYTEFTTPDGRYYDILELPY-HGN---TLSMLIAAPYEKEVPLSALTSIL--DAELI 282

Query: 274 EQKLPRNQVKVGKFMI-PRFNISFEIEASELLNKLGLTLPF--SKGGLTKMVDSPISQEL 330
            Q    N  ++ + ++ P+F++  EI+    L  LG+T  F  S+   +   D    + L
Sbjct: 283 SQ-WKGNMTRLTRLLVLPKFSLETEIDLRRPLENLGMTDMFRPSQADFSSFSD---QEFL 338

Query: 331 SVTSIFQKSFIELNEEGTIAAATARGSTGGAAPFRLPPPPPIDFVADHPFLFLIREEFSG 390
            V+   QK  IE+NE GT+A++    ST      R+ P    + + D PFLF++R   +G
Sbjct: 339 YVSQALQKVKIEVNESGTLASS----STALVVSARMAPE---EIIMDRPFLFVVRHNPTG 391

Query: 391 TILFVGKVVNP 401
           T+LF+G+V+ P
Sbjct: 392 TVLFMGQVMEP 402


>ILEU_HUMAN (P30740) Leukocyte elastase inhibitor (LEI)
           (Monocyte/neutrophil elastase inhibitor) (M/NEI) (EI)
          Length = 379

 Score =  150 bits (378), Expect = 7e-36
 Identities = 118/371 (31%), Positives = 179/371 (47%), Gaps = 29/371 (7%)

Query: 42  NVVFSPLSLNTVLIMITAGSEGPTQNQLLSFLQSESTGDLKSLCSQLVSSVLSDGAPAGG 101
           N+  SP S+++ + M+  G+ G T  QL       +  ++ S    L + +   GA    
Sbjct: 27  NIFISPFSISSAMAMVFLGTRGNTAAQLSKTFHFNTVEEVHSRFQSLNADINKRGASY-- 84

Query: 102 PCLSHVNGVWVEQSLPLQPSFKQLMTTDFKATLAAVDFINKADEVIKEVNLWANKETKGF 161
             L   N ++ E++    P F       + A LA+VDF + +++  K +N W   +T+G 
Sbjct: 85  -ILKLANRLYGEKTYNFLPEFLVSTQKTYGADLASVDFQHASEDARKTINQWVKGQTEGK 143

Query: 162 INDLLPRGSVDSLTSLIFANALYFKGVWKRPFDTSKTKDYDFDLLNGKSVKVPFMTSKNN 221
           I +LL  G VD++T L+  NA+YFKG WK  F    T +  F L       V  M  K  
Sbjct: 144 IPELLASGMVDNMTKLVLVNAIYFKGNWKDKFMKEATTNAPFRLNKKDRKTVKMMYQKKK 203

Query: 222 QFISSFDGFK--VLGLPYKQGNDKRAFSIYFFLPDEKDGLSALIDKVASD---SEFLEQK 276
                 +  K  VL LPY QG +    S+   LPD+ +  S  + K+       +  E  
Sbjct: 204 FAYGYIEDLKCRVLELPY-QGEE---LSMVILLPDDIEDESTGLKKIEEQLTLEKLHEWT 259

Query: 277 LPRN----QVKVGKFMIPRFNISFEIEASELLNKLGLTLPF--SKGGLTKMVDSPISQEL 330
            P N    +V V    +PRF +      +  L +LG+   F  SK  L+ M     ++++
Sbjct: 260 KPENLDFIEVNVS---LPRFKLEESYTLNSDLARLGVQDLFNSSKADLSGMSG---ARDI 313

Query: 331 SVTSIFQKSFIELNEEGTIAAATARGSTGGAAPFRLPPPPPIDFVADHPFLFLIREEFSG 390
            ++ I  KSF+E+NEEGT AAA    +T G A F +  P   +F ADHPFLF IR   SG
Sbjct: 314 FISKIVHKSFVEVNEEGTEAAA----ATAGIATFCMLMPEE-NFTADHPFLFFIRHNSSG 368

Query: 391 TILFVGKVVNP 401
           +ILF+G+  +P
Sbjct: 369 SILFLGRFSSP 379


>SPB9_HUMAN (P50453) Cytoplasmic antiproteinase 3 (CAP3) (CAP-3)
           (Protease inhibitor 9) (Serpin B9)
          Length = 376

 Score =  149 bits (376), Expect = 1e-35
 Identities = 103/362 (28%), Positives = 172/362 (47%), Gaps = 14/362 (3%)

Query: 42  NVVFSPLSLNTVLIMITAGSEGPTQNQLLSFLQSESTGDLKSLCSQLVSSVLSDGAPAGG 101
           NV  SP+S+++ L M+  G++G T  Q+   L   +  D+      L++ V   G     
Sbjct: 27  NVFCSPVSISSALAMVLLGAKGNTATQMAQALSLNTEEDIHRAFQSLLTEVNKAGTQY-- 84

Query: 102 PCLSHVNGVWVEQSLPLQPSFKQLMTTDFKATLAAVDFINKADEVIKEVNLWANKETKGF 161
             L   N ++ E++     +FK+     + A L  + FI  A+E  K +N W +K+T+G 
Sbjct: 85  -LLRTANRLFGEKTCQFLSTFKESCLQFYHAELKELSFIRAAEESRKHINTWVSKKTEGK 143

Query: 162 INDLLPRGSVDSLTSLIFANALYFKGVWKRPFDTSKTKDYDFDLLNGKSVKVPFMTSKNN 221
           I +LLP  S+D+ T L+  NA+YFKG W  PFD + T++  F +   +   V  M  +  
Sbjct: 144 IEELLPGSSIDAETRLVLVNAIYFKGKWNEPFDETYTREMPFKINQEEQRPVQMMYQEAT 203

Query: 222 QFISSFDGFK--VLGLPYKQGNDKRAFSIYFFLPDEKDGLSALIDKVASDSEFLEQKLPR 279
             ++     +  +L LPY     ++  S+   LPD+   LS +   +  +      K   
Sbjct: 204 FKLAHVGEVRAQLLELPYA----RKELSLLVLLPDDGVELSTVEKSLTFEKLTAWTKPDC 259

Query: 280 NQVKVGKFMIPRFNISFEIEASELLNKLGLTLPFSKGGLTKMVDSPISQELSVTSIFQKS 339
            +    + ++P+F +  + +   +L  LG+   F +G       S   ++L ++    KS
Sbjct: 260 MKSTEVEVLLPKFKLQEDYDMESVLRHLGIVDAFQQGKADLSAMS-AERDLCLSKFVHKS 318

Query: 340 FIELNEEGTIAAATARGSTGGAAPFRLPPPPPIDFVADHPFLFLIREEFSGTILFVGKVV 399
           F+E+NEEGT AAA +             P     F ADHPFLF IR   + +ILF G+  
Sbjct: 319 FVEVNEEGTEAAAASSCFVVAECCMESGP----RFCADHPFLFFIRHNRANSILFCGRFS 374

Query: 400 NP 401
           +P
Sbjct: 375 SP 376


>OVAY_CHICK (P01014) Gene Y protein (Ovalbumin-related)
          Length = 388

 Score =  149 bits (376), Expect = 1e-35
 Identities = 114/375 (30%), Positives = 180/375 (47%), Gaps = 26/375 (6%)

Query: 41  KNVVFSPLSLNTVLIMITAGSEGPTQNQLLSFLQSES-TGDLKSLCSQLVSS-------- 91
           +N+++ PLS+ T L M+  G+ G T++Q+   L  +S TG   +  SQ  SS        
Sbjct: 26  ENILYCPLSILTALAMVYLGARGNTESQMKKVLHFDSITGAGSTTDSQCGSSEYVHNLFK 85

Query: 92  -VLSD-GAPAGGPCLSHVNGVWVEQSLPLQPSFKQLMTTDFKATLAAVDFINKADEVIKE 149
            +LS+   P     L   + ++V+++  + P +       +   +  V+F   A+E  + 
Sbjct: 86  ELLSEITRPNATYSLEIADKLYVDKTFSVLPEYLSCARKFYTGGVEEVNFKTAAEEARQL 145

Query: 150 VNLWANKETKGFINDLLPRGSVDSLTSLIFANALYFKGVWKRPFDTSKTKDYDFDLLNGK 209
           +N W  KET G I DLL   S+D  T+++F N +YFKG+WK  F+T  T++  F +   +
Sbjct: 146 INSWVEKETNGQIKDLLVSSSIDFGTTMVFINTIYFKGIWKIAFNTEDTREMPFSMTKEE 205

Query: 210 SVKVPFMTSKNNQFISSF--DGFKVLGLPYKQGNDKRAFSIYFFLPDEKDGLSALIDKVA 267
           S  V  M   N+  +++   +  K+L LPY  G+     S+   LPDE  GL   I+K  
Sbjct: 206 SKPVQMMCMNNSFNVATLPAEKMKILELPYASGD----LSMLVLLPDEVSGLER-IEKTI 260

Query: 268 SDSEFLEQKLPRNQVKVG-KFMIPRFNISFEIEASELLNKLGLTLPFSKGGLTKMVDSPI 326
           +  +  E        K   K  +PR  I  +   + +L  LG+T  FS+      + S  
Sbjct: 261 NFDKLREWTSTNAMAKKSMKVYLPRMKIEEKYNLTSILMALGMTDLFSRSANLTGISS-- 318

Query: 327 SQELSVTSIFQKSFIELNEEGTIAAATARGSTGGAAPFRLPPPPPIDFVADHPFLFLIRE 386
              L ++      F+E+NEEGT     A GSTG     +       +F ADHPFLF IR 
Sbjct: 319 VDNLMISDAVHGVFMEVNEEGT----EATGSTGAIGNIKHSLELE-EFRADHPFLFFIRY 373

Query: 387 EFSGTILFVGKVVNP 401
             +  ILF G+  +P
Sbjct: 374 NPTNAILFFGRYWSP 388


>NEUS_RAT (Q9JLD2) Neuroserpin precursor (Protease inhibitor 17)
          Length = 410

 Score =  149 bits (375), Expect = 2e-35
 Identities = 116/388 (29%), Positives = 193/388 (48%), Gaps = 31/388 (7%)

Query: 25  SLNITKHLLSNQKLNEKNVVFSPLSLNTVLIMITAGSEGPTQNQLLSFLQSES--TGDLK 82
           S+N+  HL +  +  ++N++FSPLS+   + ++  G++G T  ++   +  ES  +G+  
Sbjct: 30  SVNVYNHLRATGE--DENILFSPLSIALAMGVMELGAQGSTLKEIRHSMGYESLKSGEEF 87

Query: 83  SLCSQLVSSVLSDGAPAGGPCLSHVNGVWVEQSLPLQPSFKQLMTTDFKATLAAVDFINK 142
           S      S V    A  G   +   N ++V+    +   F Q+M   F A +  VDF   
Sbjct: 88  SFLRDFSSMV---SAEEGQYVMKIANSLFVQNGFHINEEFLQMMKMYFNAEVNHVDFSEN 144

Query: 143 ADEVIKEVNLWANKETKGFINDLLPRGSVDSLTSLIFANALYFKGVWKRPFDTSKTKDYD 202
              V   +N W    T   + DL+  G  D++T L   NA+YFKG WK  F    T+ + 
Sbjct: 145 V-AVANYINKWVENYTNSLLKDLVSPGDFDAVTHLALINAVYFKGNWKSQFRPENTRTFS 203

Query: 203 FDLLNGKSVKVPFMTSKNNQFISSF-DG-------FKVLGLPYKQGNDKRAFSIYFFLPD 254
           F   +   V++P M  +   +   F DG       ++VL +PY +G++    S+   L  
Sbjct: 204 FTKDDESEVQIPMMYQQGEFYYGEFSDGSNEAGGIYQVLEIPY-EGDE---ISMMLVLSR 259

Query: 255 EKDGLSALIDKVASDSEFLEQKLPRNQVKVGKFMIPRFNISFEIEASELLNKLGLTLPFS 314
           ++  L+ L  +     + +E+     + +  +  +PRF +  EI+  ++L  LG+T  F 
Sbjct: 260 QEVPLATL--EPLLKPQLIEEWANSVKKQKVEVYLPRFTVEQEIDLKDILKALGVTEIFI 317

Query: 315 K-GGLTKMVDSPISQELSVTSIFQKSFIELNEEGTIAAATARGSTGGAAPFRLPPPPPID 373
           K   LT M D    +EL ++    KSFIE+NEEG+ AA     ++G  A  R+    P  
Sbjct: 318 KDANLTAMSD---KKELFLSKAVHKSFIEVNEEGSEAAV----ASGMIAISRMAVLFP-Q 369

Query: 374 FVADHPFLFLIREEFSGTILFVGKVVNP 401
            + DHPFLFLI+   +GTILF+G+V++P
Sbjct: 370 VIVDHPFLFLIKNRKTGTILFMGRVMHP 397


>ANT3_MOUSE (P32261) Antithrombin-III precursor (ATIII)
          Length = 465

 Score =  148 bits (373), Expect = 3e-35
 Identities = 115/382 (30%), Positives = 187/382 (48%), Gaps = 20/382 (5%)

Query: 27  NITKHLLSNQKLNEKNVVFSPLSLNTVLIMITAGSEGPTQNQLLSFLQ----SESTGDLK 82
           N  +HL  ++  N+ N+  SPLS++T   M   G+   T  QL+   +    SE T D  
Sbjct: 94  NFYQHLADSKNDND-NIFLSPLSISTAFAMTKLGACNDTLKQLMEVFKFDTISEKTSDQI 152

Query: 83  SLCSQLVSSVLSDGAPAGGPCLSHVNGVWVEQSLPLQPSFKQLMTTDFKATLAAVDFINK 142
                 ++  L   A      +S  N ++ ++SL    S++ +    + A L  +DF   
Sbjct: 153 HFFFAKLNCRLYRKANKSSDLVS-ANRLFGDKSLTFNESYQDVSEVVYGAKLQPLDFKEN 211

Query: 143 ADEVIKEVNLWANKETKGFINDLLPRGSVDSLTSLIFANALYFKGVWKRPFDTSKTKDYD 202
            ++    +N W   +T+G I D++P+G+++ LT+L+  N +YFKG+WK  F    T+   
Sbjct: 212 PEQSRVTINNWVANKTEGRIKDVIPQGAINELTALVLVNTIYFKGLWKSKFSPENTRKEP 271

Query: 203 FDLLNGKSVKVPFMTSKNN-QFISSFDGFKVLGLPYKQGNDKRAFSIYFFLPDEKDGLSA 261
           F  ++G+S  VP M  +   ++    +G +VL LP+K G+D    ++   LP  +  L+ 
Sbjct: 272 FYKVDGQSCPVPMMYQEGKFKYRRVAEGTQVLELPFK-GDD---ITMVLILPKPEKSLAK 327

Query: 262 LIDKVASDSEFLEQKLPRNQVKVGKFMIPRFNISFEIEASELLNKLGLTLPFS--KGGLT 319
           +  ++    E L++ L      +    +PRF         E L  +GL   FS  K  L 
Sbjct: 328 VEQELT--PELLQEWLDELSETMLVVHMPRFRTEDGFSLKEQLQDMGLIDLFSPEKSQLP 385

Query: 320 KMVDSPISQELSVTSIFQKSFIELNEEGTIAAATARGSTGGAAPFRLPPPPPIDFVADHP 379
            +V      +L V+  F K+F+E+NEEG+ AAA    ST      R   P  + F A+ P
Sbjct: 386 GIVAGG-RDDLYVSDAFHKAFLEVNEEGSEAAA----STSVVITGRSLNPNRVTFKANRP 440

Query: 380 FLFLIREEFSGTILFVGKVVNP 401
           FL LIRE    TI+F+G+V NP
Sbjct: 441 FLVLIREVALNTIIFMGRVANP 462


>NEUS_CHICK (Q90935) Neuroserpin precursor (Axonin-2)
          Length = 410

 Score =  147 bits (371), Expect = 5e-35
 Identities = 119/393 (30%), Positives = 195/393 (49%), Gaps = 33/393 (8%)

Query: 21  LTNVSLNITKHLLSNQKLNEKNVVFSPLSLNTVLIMITAGSEGPTQNQLLSFLQSESTGD 80
           +  +S+N+   L + ++  ++N++F PLS+   + MI  G+ G T  ++   L  +S   
Sbjct: 26  IAELSVNVYNQLRAARE--DENILFCPLSIAIAMGMIELGAHGTTLKEIRHSLGFDS--- 80

Query: 81  LKSLCSQLVSSVLSDGAPAGGP--CLSHVNGVWVEQSLPLQPSFKQLMTTDFKATLAAVD 138
           LK+         LSD A        L+  N ++V+    +   F QL+   FKA +  +D
Sbjct: 81  LKNGEEFTFLKDLSDMATTEESHYVLNMANSLYVQNGFHVSEKFLQLVKKYFKAEVENID 140

Query: 139 FINKADEVIKEVNLWANKETKGFINDLLPRGSVDSLTSLIFANALYFKGVWKRPFDTSKT 198
           F   A  V   +N W    T   I D +      +LT L+  NA+YFKG WK  F    T
Sbjct: 141 FSQSA-AVATHINKWVENHTNNMIKDFVSSRDFSALTHLVLINAIYFKGNWKSQFRPENT 199

Query: 199 KDYDFDLLNGKSVKVPFMTSKNNQFISSF-DG-------FKVLGLPYKQGNDKRAFSIYF 250
           + + F   +   V++P M  +   +   F DG       ++VL +PY +G++    S+  
Sbjct: 200 RTFSFTKDDETEVQIPMMYQQGEFYYGEFSDGSNEAGGIYQVLEIPY-EGDE---ISMMI 255

Query: 251 FLPDEKDGLSALIDKV-ASDSEFLEQKLPRNQVKVGKFMIPRFNISFEIEASELLNKLGL 309
            L  ++  L  L   V AS        + + +V+V    +PRF +  EI+  ++L  LG+
Sbjct: 256 VLSRQEVPLVTLEPLVKASLINEWANSVKKQKVEV---YLPRFTVEQEIDLKDVLKGLGI 312

Query: 310 TLPFSKGG-LTKMVDSPISQELSVTSIFQKSFIELNEEGTIAAATARGSTGGAAPFRLPP 368
           T  FS+   LT M D   ++EL +   F K+F+E+NEEG+ AAA    ++G  A  R+  
Sbjct: 313 TEVFSRSADLTAMSD---NKELYLAKAFHKAFLEVNEEGSEAAA----ASGMIAISRMAV 365

Query: 369 PPPIDFVADHPFLFLIREEFSGTILFVGKVVNP 401
             P   + DHPF FL+R   +GT+LF+G+V++P
Sbjct: 366 LYP-QVIVDHPFFFLVRNRRTGTVLFMGRVMHP 397


  Database: sprot
    Posted date:  Nov 25, 2004 10:54 AM
  Number of letters in database: 59,974,054
  Number of sequences in database:  164,201
  
Lambda     K      H
   0.317    0.136    0.385 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 47,095,566
Number of Sequences: 164201
Number of extensions: 1995602
Number of successful extensions: 6854
Number of sequences better than 10.0: 166
Number of HSP's better than 10.0 without gapping: 142
Number of HSP's successfully gapped in prelim test: 24
Number of HSP's that attempted gapping in prelim test: 6274
Number of HSP's gapped (non-prelim): 175
length of query: 404
length of database: 59,974,054
effective HSP length: 113
effective length of query: 291
effective length of database: 41,419,341
effective search space: 12053028231
effective search space used: 12053028231
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 67 (30.4 bits)