BLASTP 2.2.2 [Dec-14-2001]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= AC122166.2 + phase: 0 
         (395 letters)

Database: sprot 
           164,201 sequences; 59,974,054 total letters

Searching..................................................done

                                                                   Score     E
Sequences producing significant alignments:                        (bits)  Value

PRTZ_HORVU (P06293) Protein Z (Z4) (Major endosperm albumin)          335  9e-92
ILEU_PIG (P80229) Leukocyte elastase inhibitor (LEI) (Leucocyte ...   169  1e-41
SB10_HUMAN (P48595) Bomapin (Protease inhibitor 10) (Serpin B10)      167  3e-41
NEUS_RAT (Q9JLD2) Neuroserpin precursor (Protease inhibitor 17)       167  6e-41
PTI6_HUMAN (P35237) Placental thrombin inhibitor (Cytoplasmic an...   166  1e-40
NEUS_HUMAN (Q99574) Neuroserpin precursor (Protease inhibitor 12)     165  2e-40
NEUS_CHICK (Q90935) Neuroserpin precursor (Axonin-2)                  164  5e-40
PTI6_MOUSE (Q60854) Placental thrombin inhibitor (Protease inhib...   159  9e-39
NEUS_MOUSE (O35684) Neuroserpin precursor (Protease inhibitor 17)     158  3e-38
ILEU_HORSE (P05619) Leukocyte elastase inhibitor (LEI)                158  3e-38
ANT3_MOUSE (P32261) Antithrombin-III precursor (ATIII)                157  6e-38
SPI2_MOUSE (Q9JK88) Serpin I2 precursor (Serine protease inhibit...   155  1e-37
GDN_RAT (P07092) Glia derived nexin precursor (GDN) (Protease ne...   155  1e-37
GDN_MOUSE (Q07235) Glia derived nexin precursor (GDN) (Protease ...   155  1e-37
SCC1_HUMAN (P29508) Squamous cell carcinoma antigen 1 (SCCA-1) (...   155  2e-37
SPI2_HUMAN (O75830) Serpin I2 precursor (Myoepithelium-derived s...   154  4e-37
SPB8_HUMAN (P50452) Cytoplasmic antiproteinase 2 (CAP2) (CAP-2) ...   154  4e-37
SPB9_HUMAN (P50453) Cytoplasmic antiproteinase 3 (CAP3) (CAP-3) ...   150  4e-36
PTI6_BOVIN (O02739) Serine proteinase inhibitor B-43                  150  5e-36
PAI1_RAT (P20961) Plasminogen activator inhibitor-1 precursor (P...   150  5e-36

>PRTZ_HORVU (P06293) Protein Z (Z4) (Major endosperm albumin)
          Length = 399

 Score =  335 bits (860), Expect = 9e-92
 Identities = 179/390 (45%), Positives = 260/390 (65%), Gaps = 9/390 (2%)

Query: 8   SFTNLTNISMNITKHLLSNQKLKEENVVFSPLSLNTVLSMIATGSEGPTQKQLLSFLQSE 67
           S  + T  ++ +   + SN +    NV FSPLSL+  LS+I  G+   T+ QL++ L   
Sbjct: 12  SIAHQTRFALRLRSAISSNPERAAGNVAFSPLSLHVALSLITAGAAA-TRDQLVAILGDG 70

Query: 68  STGDLK---SLCSQLVSSVLSDGAPAGGPCLSYVNGVWVEQTIPLQPSFKQLMNTDFKAA 124
             GD K   +L  Q+V  VL++ +  GGP +++ NG++V+ ++ L+PSF++L    +KA 
Sbjct: 71  GAGDAKELNALAEQVVQFVLANESSTGGPRIAFANGIFVDASLSLKPSFEELAVCQYKAK 130

Query: 125 FAAVDFVNKANEVGEEVNFWAEKETKGLIKNLLPPGSVNSLTRLIFANALYFKGVWKQQF 184
             +VDF +K  E   +VN W E+ T GLIK +LPPGSV++ T+LI  NALYFKG W Q+F
Sbjct: 131 TQSVDFQHKTLEAVGQVNSWVEQVTTGLIKQILPPGSVDNTTKLILGNALYFKGAWDQKF 190

Query: 185 DTTKTKDYDFDLLNGKSVKVPFMTSKNDQFISSLDGFKVLGLPYKQGKDERAFSIYFFLP 244
           D + TK   F LL+G S++  FM+S   Q+ISS D  KVL LPY +G D+R FS+Y  LP
Sbjct: 191 DESNTKCDSFHLLDGSSIQTQFMSSTKKQYISSSDNLKVLKLPYAKGHDKRQFSMYILLP 250

Query: 245 DKKDGLSNLIDKVASDSEFLERNLPRRKVEVGKFRIPRFNISFEIEASELLKKLGLALPF 304
             +DGL +L  +++++ EF+E ++P++ VEVG+F++P+F IS++ EAS LL+ LGL LPF
Sbjct: 251 GAQDGLWSLAKRLSTEPEFIENHIPKQTVEVGRFQLPKFKISYQFEASSLLRALGLQLPF 310

Query: 305 T-LGGLTKMVDSPISQELYVSGIFQKSFIEVNEEGTKAAAVTVSFISSRSRYSPPPPPPI 363
           +    L++MVDS  SQ L +S +F KSF+EVNEEGT+A A TV+   + S   P     +
Sbjct: 311 SEEADLSEMVDS--SQGLEISHVFHKSFVEVNEEGTEAGAATVAMGVAMS--MPLKVDLV 366

Query: 364 DFVADHPFLFLIREEFSGTILFVGKVVNPL 393
           DFVA+HPFLFLIRE+ +G ++FVG V NPL
Sbjct: 367 DFVANHPFLFLIREDIAGVVVFVGHVTNPL 396


>ILEU_PIG (P80229) Leukocyte elastase inhibitor (LEI) (Leucocyte
           neutral proteinase inhibitor) (LNPI)
          Length = 378

 Score =  169 bits (428), Expect = 1e-41
 Identities = 123/378 (32%), Positives = 187/378 (48%), Gaps = 30/378 (7%)

Query: 26  NQKLKEENVVFSPLSLNTVLSMIATGSEGPTQKQLLSFLQSESTGDLKSLCSQLVSSVLS 85
           N+     N+  SP S+++ L+MI  G+ G T+ Q+   L  ++  D+ S    L + +  
Sbjct: 20  NESNPAGNIFISPFSISSALAMILLGTRGNTEAQMSKALHFDTVKDIHSRFQSLNADINK 79

Query: 86  DGAPAGGPCLSYVNGVWVEQTIPLQPSFKQLMNTDFKAAFAAVDFVNKANEVGEEVNFWA 145
            GA      L   N ++ E+T    P F       + A  A+VDF+  + E  + +N W 
Sbjct: 80  CGASY---ILKLANRLFGEKTYHFLPEFLASTQKTYGAELASVDFLRASEEARKAINEWV 136

Query: 146 EKETKGLIKNLLPPGSVNSLTRLIFANALYFKGVWKQQFDTTKTKDYDFDLLNGKSVKVP 205
           +++T+G I  LL  G V+S T+L+  NA+YFKG W+++F T  TKD  F L    S  V 
Sbjct: 137 KEQTEGKIPELLASGVVDSATKLVLVNAIYFKGSWQEKFMTEATKDAPFRLNKKDSKTVK 196

Query: 206 FMTSKND---QFISSLDGFKVLGLPYKQGKDERAFSIYFFLPDKKDGLSNLIDKVASDSE 262
            M  K      +I  L   +VL LPY QGKD    S+   LPD  +  S  + K+     
Sbjct: 197 MMYQKKKFPFGYIKELK-CRVLELPY-QGKD---LSMVILLPDSIEDESTGLRKIEQHLT 251

Query: 263 FLER--------NLPRRKVEVGKFRIPRFNISFEIEASELLKKLGLALPFTLGGLTKMVD 314
            LE+        NL   +V V    +PRF +    + +  L +LG+   F  G    +  
Sbjct: 252 -LEKLNEWTKPDNLELLEVNV---HLPRFRLEESYDLNAPLARLGVQDLF--GSRADLTG 305

Query: 315 SPISQELYVSGIFQKSFIEVNEEGTKAAAVTVSFISSRSRYSPPPPPPIDFVADHPFLFL 374
              +++L++S +  K+F+EVNEEGT+AAA T               P  DF+ADHPF+F 
Sbjct: 306 MSEARDLFISKVVHKAFVEVNEEGTEAAAATAGIAVFAMLM-----PEEDFIADHPFIFF 360

Query: 375 IREEFSGTILFVGKVVNP 392
           IR   S  ILF+G++ +P
Sbjct: 361 IRHNPSSNILFLGRLSSP 378


>SB10_HUMAN (P48595) Bomapin (Protease inhibitor 10) (Serpin B10)
          Length = 397

 Score =  167 bits (424), Expect = 3e-41
 Identities = 115/406 (28%), Positives = 200/406 (48%), Gaps = 37/406 (9%)

Query: 10  TNLTNISMNITKHLLSNQKLKEENVVFSPLSLNTVLSMIATGSEGPTQKQLLSFLQSE-- 67
           T++   ++ ++K L  + + K  N+ FS  S++T L+++  G++G T  Q+   LQ    
Sbjct: 6   TSINQFALELSKKLAESAQGK--NIFFSSWSISTSLTIVYLGAKGTTAAQMAQVLQFNRD 63

Query: 68  --------------------STGDLKSLCSQLVSSVLSDGAPAGGPCLSYVNGVWVEQTI 107
                               ++ ++ S    L+S +L    P     L   N ++ E+T 
Sbjct: 64  QGVKCDPESEKKRKMEFNLSNSEEIHSDFQTLISEILK---PNDDYLLKTANAIYGEKTY 120

Query: 108 PLQPSFKQLMNTDFKAAFAAVDFVNKANEVGEEVNFWAEKETKGLIKNLLPPGSVNSLTR 167
                + + M T F A    V+FV  ++++ +++N W E++T+G I+NLLP  SV+S TR
Sbjct: 121 AFHNKYLEDMKTYFGAEPQPVNFVEASDQIRKDINSWVERQTEGKIQNLLPDDSVDSTTR 180

Query: 168 LIFANALYFKGVWKQQFDTTKTKDYDFDLLNGKSVKVPFMTSKNDQFISSLDGFKVLGLP 227
           +I  NALYFKG+W+ QF    T +  F +    S  V  M  K    I  ++  K +GL 
Sbjct: 181 MILVNALYFKGIWEHQFLVQNTTEKPFRINETTSKPVQMMFMKKKLHIFHIEKPKAVGLQ 240

Query: 228 -YKQGKDERAFSIYFFLPDKKDGLSNLIDKVASDSEFLERNLPRRKVEVGKFRIPRFNIS 286
            Y + +D    S+   LP+  +GL  L   +  +      +    ++   +  +P+F + 
Sbjct: 241 LYYKSRD---LSLLILLPEDINGLEQLEKAITYEKLNEWTSADMMELYEVQLHLPKFKLE 297

Query: 287 FEIEASELLKKLGLALPFTLGGLTKMVDSPISQELYVSGIFQKSFIEVNEEGTKAAAVTV 346
              +    L  +G++  F+            ++ L++S +F K+F+E+NE+GT+AAA + 
Sbjct: 298 DSYDLKSTLSSMGMSDAFS-QSKADFSGMSSARNLFLSNVFHKAFVEINEQGTEAAAGSG 356

Query: 347 SFISSRSRYSPPPPPPIDFVADHPFLFLIREEFSGTILFVGKVVNP 392
           S I  R R      P I+F A+HPFLF IR   + TILF G++ +P
Sbjct: 357 SEIDIRIRV-----PSIEFNANHPFLFFIRHNKTNTILFYGRLCSP 397


>NEUS_RAT (Q9JLD2) Neuroserpin precursor (Protease inhibitor 17)
          Length = 410

 Score =  167 bits (422), Expect = 6e-41
 Identities = 128/407 (31%), Positives = 206/407 (50%), Gaps = 36/407 (8%)

Query: 1   MQNLI-GKSFTNLT--NISMNITKHLLSNQKLKEENVVFSPLSLNTVLSMIATGSEGPTQ 57
           +Q+L+ G +F + T    S+N+  HL +  +  +EN++FSPLS+   + ++  G++G T 
Sbjct: 12  LQSLVTGAAFPDETIAEWSVNVYNHLRATGE--DENILFSPLSIALAMGVMELGAQGSTL 69

Query: 58  KQLLSFLQSES--TGDLKSLCSQLVSSVLSDGAPAGGPCLSYVNGVWVEQTIPLQPSFKQ 115
           K++   +  ES  +G+  S      S V    A  G   +   N ++V+    +   F Q
Sbjct: 70  KEIRHSMGYESLKSGEEFSFLRDFSSMV---SAEEGQYVMKIANSLFVQNGFHINEEFLQ 126

Query: 116 LMNTDFKAAFAAVDFVNKANEVGEEVNFWAEKETKGLIKNLLPPGSVNSLTRLIFANALY 175
           +M   F A    VDF      V   +N W E  T  L+K+L+ PG  +++T L   NA+Y
Sbjct: 127 MMKMYFNAEVNHVDFSENV-AVANYINKWVENYTNSLLKDLVSPGDFDAVTHLALINAVY 185

Query: 176 FKGVWKQQFDTTKTKDYDFDLLNGKSVKVPFMTSKNDQFISSL-DG-------FKVLGLP 227
           FKG WK QF    T+ + F   +   V++P M  + + +     DG       ++VL +P
Sbjct: 186 FKGNWKSQFRPENTRTFSFTKDDESEVQIPMMYQQGEFYYGEFSDGSNEAGGIYQVLEIP 245

Query: 228 YKQGKDERAFSIYFFLPDKKDGLSNLIDKVASD-SEFLERNLPRRKVEVGKFRIPRFNIS 286
           Y+  +     S+   L  ++  L+ L   +     E    ++ ++KVEV    +PRF + 
Sbjct: 246 YEGDE----ISMMLVLSRQEVPLATLEPLLKPQLIEEWANSVKKQKVEV---YLPRFTVE 298

Query: 287 FEIEASELLKKLGLALPFTL-GGLTKMVDSPISQELYVSGIFQKSFIEVNEEGTKAAAVT 345
            EI+  ++LK LG+   F     LT M D    +EL++S    KSFIEVNEEG++AA  +
Sbjct: 299 QEIDLKDILKALGVTEIFIKDANLTAMSD---KKELFLSKAVHKSFIEVNEEGSEAAVAS 355

Query: 346 VSFISSRSRYSPPPPPPIDFVADHPFLFLIREEFSGTILFVGKVVNP 392
                SR     P       + DHPFLFLI+   +GTILF+G+V++P
Sbjct: 356 GMIAISRMAVLFP-----QVIVDHPFLFLIKNRKTGTILFMGRVMHP 397


>PTI6_HUMAN (P35237) Placental thrombin inhibitor (Cytoplasmic
           antiproteinase) (CAP) (Protease inhibitor 6) (PI-6)
          Length = 376

 Score =  166 bits (420), Expect = 1e-40
 Identities = 125/386 (32%), Positives = 199/386 (51%), Gaps = 30/386 (7%)

Query: 16  SMNITKHLLSNQKLKEENVVFSPLSLNTVLSMIATGSEGPT---QKQLLSFLQSESTGDL 72
           ++N+ K L    K   +NV FSP+S++  L+M+  G++G T     Q+LSF +S   GD+
Sbjct: 12  ALNLLKTL---GKDNSKNVFFSPMSMSCALAMVYMGAKGNTAAQMAQILSFNKSGGGGDI 68

Query: 73  KSLCSQLVSSVLSDGAPAGGPCLSYVNGVWVEQTIPLQPSFKQLMNTDFKAAFAAVDFVN 132
                 L++ V   G       L   N ++ E++     SF+      ++A    +DF++
Sbjct: 69  HQGFQSLLTEVNKTGTQY---LLRVANRLFGEKSCDFLSSFRDSCQKFYQAEMEELDFIS 125

Query: 133 KANEVGEEVNFWAEKETKGLIKNLLPPGSVNSLTRLIFANALYFKGVWKQQFDTTKTKDY 192
              +  + +N W  ++T+G I  LL PGSV+ LTRL+  NA+YF+G W +QFD   T++ 
Sbjct: 126 AVEKSRKHINTWVAEKTEGKIAELLSPGSVDPLTRLVLVNAVYFRGNWDEQFDKENTEER 185

Query: 193 DFDLLNGKSVKVPFMTSKNDQFISSLDG---FKVLGLPYKQGKDERAFSIYFFLPDKKDG 249
            F +   +   V  M  K   F  +  G    ++L LPY  GK+    ++   LPD+   
Sbjct: 186 LFKVSKNEEKPVQMM-FKQSTFKKTYIGEIFTQILVLPY-VGKE---LNMIIMLPDETTD 240

Query: 250 LSNLIDKVASDSEFLE-RNLPRRKVEVGKFRIPRFNISFEIEASELLKKLGLALPFTLGG 308
           L   ++K  +  +F+E   L     E  +  +PRF +    +   +L+ LG+   F LG 
Sbjct: 241 L-RTVEKELTYEKFVEWTRLDMMDEEEVEVSLPRFKLEESYDMESVLRNLGMTDAFELG- 298

Query: 309 LTKMVDSPISQ-ELYVSGIFQKSFIEVNEEGTKAAAVTVSFISSR-SRYSPPPPPPIDFV 366
             K   S +SQ +L +S +  KSF+EVNEEGT+AAA T + +  R +R+ P       F 
Sbjct: 299 --KADFSGMSQTDLSLSKVVHKSFVEVNEEGTEAAAATAAIMMMRCARFVP------RFC 350

Query: 367 ADHPFLFLIREEFSGTILFVGKVVNP 392
           ADHPFLF I+   +  ILF G+  +P
Sbjct: 351 ADHPFLFFIQHSKTNGILFCGRFSSP 376


>NEUS_HUMAN (Q99574) Neuroserpin precursor (Protease inhibitor 12)
          Length = 410

 Score =  165 bits (418), Expect = 2e-40
 Identities = 122/393 (31%), Positives = 200/393 (50%), Gaps = 33/393 (8%)

Query: 12  LTNISMNITKHLLSNQKLKEENVVFSPLSLNTVLSMIATGSEGPTQKQLLSFLQSES--T 69
           + ++S+N+   L +  +  +EN++FSPLS+   + M+  G++G TQK++   +  +S   
Sbjct: 26  IADLSVNMYNRLRATGE--DENILFSPLSIALAMGMMELGAQGSTQKEIRHSMGYDSLKN 83

Query: 70  GDLKSLCSQLVSSVLSDGAPAGGPCLSYVNGVWVEQTIPLQPSFKQLMNTDFKAAFAAVD 129
           G+  S   +  + V    A      +   N ++V+    +   F Q+M   F AA   VD
Sbjct: 84  GEEFSFLKEFSNMVT---AKESQYVMKIANSLFVQNGFHVNEEFLQMMKKYFNAAVNHVD 140

Query: 130 FVNKANEVGEEVNFWAEKETKGLIKNLLPPGSVNSLTRLIFANALYFKGVWKQQFDTTKT 189
           F      V   +N W E  T  L+K+L+ P   ++ T L   NA+YFKG WK QF    T
Sbjct: 141 FSQNV-AVANYINKWVENNTNNLVKDLVSPRDFDAATYLALINAVYFKGNWKSQFRPENT 199

Query: 190 KDYDFDLLNGKSVKVPFMTSKNDQFISSL-DG-------FKVLGLPYKQGKDERAFSIYF 241
           + + F   +   V++P M  + + +     DG       ++VL +PY+  +     S+  
Sbjct: 200 RTFSFTKDDESEVQIPMMYQQGEFYYGEFSDGSNEAGGIYQVLEIPYEGDE----ISMML 255

Query: 242 FLPDKKDGLSNLIDKV-ASDSEFLERNLPRRKVEVGKFRIPRFNISFEIEASELLKKLGL 300
            L  ++  L+ L   V A   E    ++ ++KVEV    +PRF +  EI+  ++LK LG+
Sbjct: 256 VLSRQEVPLATLEPLVKAQLVEEWANSVKKQKVEV---YLPRFTVEQEIDLKDVLKALGI 312

Query: 301 ALPFTL-GGLTKMVDSPISQELYVSGIFQKSFIEVNEEGTKAAAVTVSFISSRSRYSPPP 359
              F     LT + D   ++E+++S    KSF+EVNEEG++AAAV+     SR     P 
Sbjct: 313 TEIFIKDANLTGLSD---NKEIFLSKAIHKSFLEVNEEGSEAAAVSGMIAISRMAVLYP- 368

Query: 360 PPPIDFVADHPFLFLIREEFSGTILFVGKVVNP 392
                 + DHPF FLIR   +GTILF+G+V++P
Sbjct: 369 ----QVIVDHPFFFLIRNRRTGTILFMGRVMHP 397


>NEUS_CHICK (Q90935) Neuroserpin precursor (Axonin-2)
          Length = 410

 Score =  164 bits (414), Expect = 5e-40
 Identities = 123/393 (31%), Positives = 199/393 (50%), Gaps = 33/393 (8%)

Query: 12  LTNISMNITKHLLSNQKLKEENVVFSPLSLNTVLSMIATGSEGPTQKQLLSFLQSESTGD 71
           +  +S+N+   L + ++  +EN++F PLS+   + MI  G+ G T K++   L  +S   
Sbjct: 26  IAELSVNVYNQLRAARE--DENILFCPLSIAIAMGMIELGAHGTTLKEIRHSLGFDS--- 80

Query: 72  LKSLCSQLVSSVLSDGAPAGGP--CLSYVNGVWVEQTIPLQPSFKQLMNTDFKAAFAAVD 129
           LK+         LSD A        L+  N ++V+    +   F QL+   FKA    +D
Sbjct: 81  LKNGEEFTFLKDLSDMATTEESHYVLNMANSLYVQNGFHVSEKFLQLVKKYFKAEVENID 140

Query: 130 FVNKANEVGEEVNFWAEKETKGLIKNLLPPGSVNSLTRLIFANALYFKGVWKQQFDTTKT 189
           F   A  V   +N W E  T  +IK+ +     ++LT L+  NA+YFKG WK QF    T
Sbjct: 141 FSQSA-AVATHINKWVENHTNNMIKDFVSSRDFSALTHLVLINAIYFKGNWKSQFRPENT 199

Query: 190 KDYDFDLLNGKSVKVPFMTSKNDQFISSL-DG-------FKVLGLPYKQGKDERAFSIYF 241
           + + F   +   V++P M  + + +     DG       ++VL +PY+  +     S+  
Sbjct: 200 RTFSFTKDDETEVQIPMMYQQGEFYYGEFSDGSNEAGGIYQVLEIPYEGDE----ISMMI 255

Query: 242 FLPDKKDGLSNLIDKV-ASDSEFLERNLPRRKVEVGKFRIPRFNISFEIEASELLKKLGL 300
            L  ++  L  L   V AS       ++ ++KVEV    +PRF +  EI+  ++LK LG+
Sbjct: 256 VLSRQEVPLVTLEPLVKASLINEWANSVKKQKVEV---YLPRFTVEQEIDLKDVLKGLGI 312

Query: 301 ALPFTLGG-LTKMVDSPISQELYVSGIFQKSFIEVNEEGTKAAAVTVSFISSRSRYSPPP 359
              F+    LT M D   ++ELY++  F K+F+EVNEEG++AAA +     SR     P 
Sbjct: 313 TEVFSRSADLTAMSD---NKELYLAKAFHKAFLEVNEEGSEAAAASGMIAISRMAVLYP- 368

Query: 360 PPPIDFVADHPFLFLIREEFSGTILFVGKVVNP 392
                 + DHPF FL+R   +GT+LF+G+V++P
Sbjct: 369 ----QVIVDHPFFFLVRNRRTGTVLFMGRVMHP 397


>PTI6_MOUSE (Q60854) Placental thrombin inhibitor (Protease
           inhibitor 6) (PI-6)
          Length = 378

 Score =  159 bits (403), Expect = 9e-39
 Identities = 113/370 (30%), Positives = 184/370 (49%), Gaps = 25/370 (6%)

Query: 32  ENVVFSPLSLNTVLSMIATGSEGPTQKQLLSFLQSEST-----GDLKSLCSQLVSSVLSD 86
           +NV  SP+S+++ L+M+  G++G T  Q+   L  +       GD+      L++ V   
Sbjct: 25  KNVFLSPMSISSALAMVFMGAKGTTASQMAQALALDKCSGNGGGDVHQGFQSLLTEVNKT 84

Query: 87  GAPAGGPCLSYVNGVWVEQTIPLQPSFKQLMNTDFKAAFAAVDFVNKANEVGEEVNFWAE 146
           G       L   N ++ ++T  L  SFK      ++A    +DF     E  + +N W  
Sbjct: 85  GTQY---LLRTANRLFGDKTCDLLASFKDSCLKFYEAELEELDFQGATEESRQHINTWVA 141

Query: 147 KETKGLIKNLLPPGSVNSLTRLIFANALYFKGVWKQQFDTTKTKDYDFDLLNGKSVKVPF 206
           K+T+  IK +L PG+VNS T L+  NA+YFKG W++QF+   T++  F +   +   V  
Sbjct: 142 KKTEDKIKEVLSPGTVNSDTSLVLVNAIYFKGNWEKQFNKEHTREMPFKVSKNEEKPVQM 201

Query: 207 MTSKNDQFISSLDGF--KVLGLPYKQGKDERAFSIYFFLPDKKDGLSNLIDKVASDSEFL 264
           M  K+   ++ +     K+L LPY   +     ++   LPD+   LS  ++K  +  +F+
Sbjct: 202 MFKKSTFKMTYIGEIFTKILLLPYVSSE----LNMIIMLPDEHVELST-VEKEVTYEKFI 256

Query: 265 E-RNLPRRKVEVGKFRIPRFNISFEIEASELLKKLGLALPFTLGGLTKMVDSPISQELYV 323
           E   L +   E  +  +P+F +      ++ L KLG+   F  GG          Q L++
Sbjct: 257 EWTRLDKMDEEEVEVFLPKFKLEENYNMNDALYKLGMTDAF--GGRADFSGMSSKQGLFL 314

Query: 324 SGIFQKSFIEVNEEGTKAAAVTVSFISSR-SRYSPPPPPPIDFVADHPFLFLIREEFSGT 382
           S +  K+F+EVNEEGT+AAA T   ++ R  R++P       F ADHPFLF I    +  
Sbjct: 315 SKVVHKAFVEVNEEGTEAAAATAGMMTVRCMRFTP------RFCADHPFLFFIHHVKTNG 368

Query: 383 ILFVGKVVNP 392
           ILF G+  +P
Sbjct: 369 ILFCGRFSSP 378


>NEUS_MOUSE (O35684) Neuroserpin precursor (Protease inhibitor 17)
          Length = 410

 Score =  158 bits (399), Expect = 3e-38
 Identities = 121/393 (30%), Positives = 192/393 (48%), Gaps = 33/393 (8%)

Query: 12  LTNISMNITKHLLSNQKLKEENVVFSPLSLNTVLSMIATGSEGPTQKQLLSFLQSEST-- 69
           +T  S+N+  HL    +  +EN++FSPLS+   + M+  G++G T+K++   +  E    
Sbjct: 26  ITEWSVNMYNHLRGTGE--DENILFSPLSIALAMGMMELGAQGSTRKEIRHSMGYEGLKG 83

Query: 70  GDLKSLCSQLVSSVLSDGAPAGGPCLSYVNGVWVEQTIPLQPSFKQLMNTDFKAAFAAVD 129
           G+  S      +      A      +   N ++V+    +   F Q++   F A    VD
Sbjct: 84  GEEFSFLRDFSNMA---SAEENQYVMKLANSLFVQNGFHVNEEFLQMLKMYFNAEVNHVD 140

Query: 130 FVNKANEVGEEVNFWAEKETKGLIKNLLPPGSVNSLTRLIFANALYFKGVWKQQFDTTKT 189
           F      V   +N W E  T  L+K+L+ P   + +T L   NA+YFKG WK QF    T
Sbjct: 141 FSQNV-AVANSINKWVENYTNSLLKDLVSPEDFDGVTNLALINAVYFKGNWKSQFRPENT 199

Query: 190 KDYDFDLLNGKSVKVPFMTSKNDQFISSL-DG-------FKVLGLPYKQGKDERAFSIYF 241
           + + F   +   V++P M  + + +     DG       ++VL +PY+  +     S+  
Sbjct: 200 RTFSFTKDDESEVQIPMMYQQGEFYYGEFSDGSNEAGGIYQVLEIPYEGDE----ISMML 255

Query: 242 FLPDKKDGLSNLIDKV-ASDSEFLERNLPRRKVEVGKFRIPRFNISFEIEASELLKKLGL 300
            L  ++  L+ L   + A   E    ++ ++KVEV    +PRF +  EI+  ++LK LG+
Sbjct: 256 ALSRQEVPLATLEPLLKAQLIEEWANSVKKQKVEV---YLPRFTVEQEIDLKDILKALGV 312

Query: 301 ALPFTL-GGLTKMVDSPISQELYVSGIFQKSFIEVNEEGTKAAAVTVSFISSRSRYSPPP 359
              F     LT M D    +EL++S    KS IEVNEEG++AAA +     SR     P 
Sbjct: 313 TEIFIKDANLTAMSD---KKELFLSKAVHKSCIEVNEEGSEAAAASGMIAISRMAVLYP- 368

Query: 360 PPPIDFVADHPFLFLIREEFSGTILFVGKVVNP 392
                 + DHPFL+LIR   SG ILF+G+V+NP
Sbjct: 369 ----QVIVDHPFLYLIRNRKSGIILFMGRVMNP 397


>ILEU_HORSE (P05619) Leukocyte elastase inhibitor (LEI)
          Length = 379

 Score =  158 bits (399), Expect = 3e-38
 Identities = 116/369 (31%), Positives = 181/369 (48%), Gaps = 25/369 (6%)

Query: 33  NVVFSPLSLNTVLSMIATGSEGPTQKQLLSFLQSESTGDLKSLCSQLVSSVLSDGAPAGG 92
           N+  SPLS+++ L+MI  G+ G T  Q+   L  ++  D+ S    L + +   GAP   
Sbjct: 27  NIFISPLSISSALAMIFLGTRGNTAAQVSKALYFDTVEDIHSRFQSLNADINKPGAPY-- 84

Query: 93  PCLSYVNGVWVEQTIPLQPSFKQLMNTDFKAAFAAVDFVNKANEVGEEVNFWAEKETKGL 152
             L   N ++ E+T      F       + A  A+VDF     +  +E+N W + +T+G 
Sbjct: 85  -ILKLANRLYGEKTYNFLADFLASTQKMYGAELASVDFQQAPEDARKEINEWVKGQTEGK 143

Query: 153 IKNLLPPGSVNSLTRLIFANALYFKGVWKQQFDTTKTKDYDFDLLNGKSVKVPFMTSKND 212
           I  LL  G V+++T+L+  NA+YFKG W+++F    T+D  F L    +  V  M  K  
Sbjct: 144 IPELLVKGMVDNMTKLVLVNAIYFKGNWQEKFMKEATRDAPFRLNKKDTKTVKMMYQKKK 203

Query: 213 QFISSLDGFK--VLGLPYKQGKDERAFSIYFFLPDKKDGLSNLIDKVASDSEFLE----- 265
              + ++  K  VL LPY QGK+    S+   LPD  +  S  ++K+       +     
Sbjct: 204 FPYNYIEDLKCRVLELPY-QGKE---LSMIILLPDDIEDESTGLEKIEKQLTLEKLREWT 259

Query: 266 --RNLPRRKVEVGKFRIPRFNISFEIEASELLKKLGLALPFTLGGLTKMVDSPISQELYV 323
              NL   +V V    +PRF +    + +  L +LG+   F   G   +     +++L+V
Sbjct: 260 KPENLYLAEVNV---HLPRFKLEESYDLTSHLARLGVQDLFN-RGKADLSGMSGARDLFV 315

Query: 324 SGIFQKSFIEVNEEGTKAAAVTVSFISSRSRYSPPPPPPIDFVADHPFLFLIREEFSGTI 383
           S I  KSF+++NEEGT+AAA T   I           P  +F ADHPF+F IR   S  I
Sbjct: 316 SKIIHKSFVDLNEEGTEAAAATAGTIMLAMLM-----PEENFNADHPFIFFIRHNPSANI 370

Query: 384 LFVGKVVNP 392
           LF+G+  +P
Sbjct: 371 LFLGRFSSP 379


>ANT3_MOUSE (P32261) Antithrombin-III precursor (ATIII)
          Length = 465

 Score =  157 bits (396), Expect = 6e-38
 Identities = 116/390 (29%), Positives = 192/390 (48%), Gaps = 26/390 (6%)

Query: 13  TNISMNITKHLLSNQKLKEENVVFSPLSLNTVLSMIATGSEGPTQKQLLSFLQ----SES 68
           +  + N  +HL ++ K   +N+  SPLS++T  +M   G+   T KQL+   +    SE 
Sbjct: 89  SRFATNFYQHL-ADSKNDNDNIFLSPLSISTAFAMTKLGACNDTLKQLMEVFKFDTISEK 147

Query: 69  TGDLKSLCSQLVSSVLSDGAPAGGPCLSYVNGVWVEQTIPLQPSFKQLMNTDFKAAFAAV 128
           T D        ++  L   A      +S  N ++ ++++    S++ +    + A    +
Sbjct: 148 TSDQIHFFFAKLNCRLYRKANKSSDLVS-ANRLFGDKSLTFNESYQDVSEVVYGAKLQPL 206

Query: 129 DFVNKANEVGEEVNFWAEKETKGLIKNLLPPGSVNSLTRLIFANALYFKGVWKQQFDTTK 188
           DF     +    +N W   +T+G IK+++P G++N LT L+  N +YFKG+WK +F    
Sbjct: 207 DFKENPEQSRVTINNWVANKTEGRIKDVIPQGAINELTALVLVNTIYFKGLWKSKFSPEN 266

Query: 189 TKDYDFDLLNGKSVKVPFMTSKND-QFISSLDGFKVLGLPYKQGKDERAFSIYFFLPDKK 247
           T+   F  ++G+S  VP M  +   ++    +G +VL LP+K G D    ++   LP  +
Sbjct: 267 TRKEPFYKVDGQSCPVPMMYQEGKFKYRRVAEGTQVLELPFK-GDD---ITMVLILPKPE 322

Query: 248 DGLSNLIDKVASDSEFLERNLPRRKVEVGKFRIPRFNISFEIEASELLKKLGLALPFT-- 305
             L+ +  ++    E L+  L      +    +PRF         E L+ +GL   F+  
Sbjct: 323 KSLAKVEQELT--PELLQEWLDELSETMLVVHMPRFRTEDGFSLKEQLQDMGLIDLFSPE 380

Query: 306 ---LGGLTKMVDSPISQELYVSGIFQKSFIEVNEEGTKAAAVTVSFISSRSRYSPPPPPP 362
              L G+     +    +LYVS  F K+F+EVNEEG++AAA T   I+ RS      P  
Sbjct: 381 KSQLPGIV----AGGRDDLYVSDAFHKAFLEVNEEGSEAAASTSVVITGRSL----NPNR 432

Query: 363 IDFVADHPFLFLIREEFSGTILFVGKVVNP 392
           + F A+ PFL LIRE    TI+F+G+V NP
Sbjct: 433 VTFKANRPFLVLIREVALNTIIFMGRVANP 462


>SPI2_MOUSE (Q9JK88) Serpin I2 precursor (Serine protease inhibitor
           14)
          Length = 405

 Score =  155 bits (393), Expect = 1e-37
 Identities = 111/369 (30%), Positives = 189/369 (51%), Gaps = 25/369 (6%)

Query: 31  EENVVFSPLSLNTVLSMIATGSEGPTQKQLLSFLQSEST--GDLKSLCSQLVSSVLSDGA 88
           + N++FSPL    +L M+  G++G  Q+Q+L  L+   T  G+  S+   L S++     
Sbjct: 42  KNNIIFSPLGTTMLLGMVQLGAKGKAQQQILKTLRMRGTPAGEEFSVLKSLFSAISKKKQ 101

Query: 89  PAGGPCLSYVNGVWVEQTIPLQPSFKQLMNTDFKAAFAAVDFVNKANEVGEEVNFWAEKE 148
                  +  + +++++   ++ ++       F++A   VDF++ A    + ++ W E +
Sbjct: 102 EF---TFNLASALYLQEGFIVKETYLHSNKEFFQSATKLVDFLD-AKTSAQAISTWVESK 157

Query: 149 TKGLIKNLLPPGSVNSLTRLIFANALYFKGVWKQQFDTTKTKDYDFDLLNGKSVKVPFM- 207
           T G IKN+        LTRL+  NA+YFKG WKQ+F    T+  DF   +G +VKVP M 
Sbjct: 158 TDGKIKNMFSEEEFGPLTRLVLVNAIYFKGDWKQKFRKEDTEMTDFTKKDGSTVKVPMMK 217

Query: 208 ---TSKNDQFISSLDGFKVLGLPYKQGKDERAFSIYFFLPDKKDGLSNLIDKVASDSEFL 264
               ++   F  S    +VL LPYK  +    FS+   LP +   +  + ++V   +  +
Sbjct: 218 ALLRAQYGYFSQSSMTCQVLELPYKADE----FSLVIILPTEDTSIEEVENQVT--APHV 271

Query: 265 ERNLPRRKVEVGKFRIPRFNISFEIEASELLKKLGLALPFTLG-GLTKMVDSPISQELYV 323
            R       E  +  +PRF I  +++  E L  L +   F+ G  L+ + D   S E+YV
Sbjct: 272 RRWFSELHEEEVEVSLPRFKIEQKLDLKEALYSLNVTEIFSGGCDLSGITD---SSEVYV 328

Query: 324 SGIFQKSFIEVNEEGTKAAAVTVSFISSRSRYSPPPPPPIDFVADHPFLFLIREEFSGTI 383
           S + QK F E+NE+G++AAA T   I +    +        F+A+HPFLF+++   + +I
Sbjct: 329 SRVMQKVFFEINEDGSEAAASTGINIPAIMSLT-----QTQFLANHPFLFILKHIRTESI 383

Query: 384 LFVGKVVNP 392
           LF+GKV +P
Sbjct: 384 LFMGKVTDP 392


>GDN_RAT (P07092) Glia derived nexin precursor (GDN) (Protease nexin
           I) (PN-1)
          Length = 397

 Score =  155 bits (393), Expect = 1e-37
 Identities = 123/383 (32%), Positives = 195/383 (50%), Gaps = 41/383 (10%)

Query: 26  NQKLKE---ENVVFSPLSLNTVLSMIATGSEGPTQKQLLSFLQSESTGD---LKSLCSQL 79
           NQ +K    ENVV SP  + ++L M+  G++G T+KQL + ++    G    LK +   +
Sbjct: 40  NQIIKSQPHENVVISPHGIASILGMLQLGADGRTKKQLSTVMRYNVNGVGKVLKKINKAI 99

Query: 80  VSSVLSDGAPAGGPCLSYVNGVWVEQTIPLQPSFKQLMNTDFKAAFAAVDFVNKANEVGE 139
           VS    D        ++  N V+V     ++  F       F+    +V+F + A+   +
Sbjct: 100 VSKKNKD-------IVTVANAVFVRNGFKVEVPFAARNKEVFQCEVQSVNFQDPASAC-D 151

Query: 140 EVNFWAEKETKGLIKNLLPPGSVNS-LTRLIFANALYFKGVWKQQFDTTKTKDYDFDLLN 198
            +NFW + ET+G+I NLL P  ++S LT+L+  NA+YFKG+WK +F    TK   F   +
Sbjct: 152 AINFWVKNETRGMIDNLLSPNLIDSALTKLVLVNAVYFKGLWKSRFQPENTKKRTFVAGD 211

Query: 199 GKSVKVPFMT------SKNDQFISSLDGFKVLGLPYKQGKDERAFSIYFFLP-DKKDGLS 251
           GKS +VP +       S + +  + L  +  + LPY       + S+   LP +    LS
Sbjct: 212 GKSYQVPMLAQLSVFRSGSTKTPNGL-WYNFIELPY----HGESISMLIALPTESSTPLS 266

Query: 252 NLIDKVASD--SEFLERNLPRRKVEVGKFRIPRFNISFEIEASELLKKLGLALPFTLGGL 309
            +I  +++   + ++   +P+R   V    +P+F    + +  E LK LG+   F     
Sbjct: 267 AIIPHISTKTINSWMNTMVPKRMQLV----LPKFTALAQTDLKEPLKALGITEMFE-PSK 321

Query: 310 TKMVDSPISQELYVSGIFQKSFIEVNEEGTKAAAVTVSFISSRSRYSPPPPPPIDFVADH 369
                   S+ L+VS I QK+ IEV+E+GTKAA VT + + +RS  SPP      F+ D 
Sbjct: 322 ANFAKITRSESLHVSHILQKAKIEVSEDGTKAAVVTTAILIARS--SPP-----WFIVDR 374

Query: 370 PFLFLIREEFSGTILFVGKVVNP 392
           PFLF IR   +G ILF+G+V  P
Sbjct: 375 PFLFCIRHNPTGAILFLGQVNKP 397


>GDN_MOUSE (Q07235) Glia derived nexin precursor (GDN) (Protease
           nexin I) (PN-1) (Serine protease-inhibitor-4)
          Length = 397

 Score =  155 bits (393), Expect = 1e-37
 Identities = 124/385 (32%), Positives = 197/385 (50%), Gaps = 45/385 (11%)

Query: 26  NQKLKE---ENVVFSPLSLNTVLSMIATGSEGPTQKQLLSFLQSESTGD---LKSLCSQL 79
           NQ +K    ENVV SP  + ++L M+  G++G T+KQL + ++    G    LK +   +
Sbjct: 40  NQIIKSRPHENVVVSPHGIASILGMLQLGADGKTKKQLSTVMRYNVNGVGKVLKKINKAI 99

Query: 80  VSSVLSDGAPAGGPCLSYVNGVWVEQTIPLQPSFKQLMNTDFKAAFAAVDFVNKANEVGE 139
           VS    D        ++  N V++     ++  F       F+     V+F + A+   E
Sbjct: 100 VSKKNKD-------IVTVANAVFLRNGFKMEVPFAVRNKDVFQCEVQNVNFQDPAS-ASE 151

Query: 140 EVNFWAEKETKGLIKNLLPPGSVN-SLTRLIFANALYFKGVWKQQFDTTKTKDYDFDLLN 198
            +NFW + ET+G+I NLL P  ++ +LTRL+  NA+YFKG+WK +F    TK   F   +
Sbjct: 152 SINFWVKNETRGMIDNLLSPNLIDGALTRLVLVNAVYFKGLWKSRFQPESTKKRTFVAGD 211

Query: 199 GKSVKVPFMT------SKNDQFISSLDGFKVLGLPYKQGKDERAFSIYFFLP-DKKDGLS 251
           GKS +VP +       S + +  + L  +  + LPY       + S+   LP +    LS
Sbjct: 212 GKSYQVPMLAQLSVFRSGSTRTPNGL-WYNFIELPY----HGESISMLIALPTESSTPLS 266

Query: 252 NLIDKVASDS--EFLERNLPRRKVEVGKFRIPRFNISFEIEASELLKKLGLALPF--TLG 307
            +I  + + +   ++   +P+R   V    +P+F    + +  E LK LG+   F  +  
Sbjct: 267 AIIPHITTKTIDSWMNTMVPKRMQLV----LPKFTAVAQTDLKEPLKALGITEMFEPSKA 322

Query: 308 GLTKMVDSPISQELYVSGIFQKSFIEVNEEGTKAAAVTVSFISSRSRYSPPPPPPIDFVA 367
             TK+     S+ L+VS I QK+ IEV+E+GTKA+A T + + +RS  SPP      F+ 
Sbjct: 323 NFTKITR---SESLHVSHILQKAKIEVSEDGTKASAATTAILIARS--SPP-----WFIV 372

Query: 368 DHPFLFLIREEFSGTILFVGKVVNP 392
           D PFLF IR   +G ILF+G+V  P
Sbjct: 373 DRPFLFSIRHNPTGAILFLGQVNKP 397


>SCC1_HUMAN (P29508) Squamous cell carcinoma antigen 1 (SCCA-1)
           (Protein T4-A)
          Length = 390

 Score =  155 bits (391), Expect = 2e-37
 Identities = 112/387 (28%), Positives = 185/387 (46%), Gaps = 37/387 (9%)

Query: 27  QKLKEENVVFSPLSLNTVLSMIATGSEGPTQKQLLSFLQSE-----STGDLKS------- 74
           +K KE N+ +SP+S+ + L M+  G++  T +Q+   L  +     +TG   +       
Sbjct: 20  RKSKENNIFYSPISITSALGMVLLGAKDNTAQQIKKVLHFDQVTENTTGKAATYHVDRSG 79

Query: 75  -LCSQLVSSVLSDGAPAGGPCLSYVNGVWVEQTIPLQPSFKQLMNTDFKAAFAAVDFVNK 133
            +  Q    +           L   N ++ E+T      +   +   ++ +  +VDF N 
Sbjct: 80  NVHHQFQKLLTEFNKSTDAYELKIANKLFGEKTYLFLQEYLDAIKKFYQTSVESVDFANA 139

Query: 134 ANEVGEEVNFWAEKETKGLIKNLLPPGSVNSLTRLIFANALYFKGVWKQQFDTTKTKDYD 193
             E  +++N W E +T   IKNL+P G++ S T L+  NA+YFKG W+++F+   TK+  
Sbjct: 140 PEESRKKINSWVESQTNEKIKNLIPEGNIGSNTTLVLVNAIYFKGQWEKKFNKEDTKEEK 199

Query: 194 FDLLNGKSVKVPFMTSKNDQFISSLDGF--KVLGLPYKQGKDERAFSIYFFLPDKKDGLS 251
           F         +  M        +SL+    KVL +PYK GKD    S+   LP++ DGL 
Sbjct: 200 FWPNKNTYKSIQMMRQYTSFHFASLEDVQAKVLEIPYK-GKD---LSMIVLLPNEIDGLQ 255

Query: 252 NLIDKVASDSEFLERNLPRRKVEVGKFRIPRFNISFEIEASELLKKLGLALPFT----LG 307
            L +K+ ++      +L   +       +PRF +    +  + L+ +G+   F     L 
Sbjct: 256 KLEEKLTAEKLMEWTSLQNMRETRVDLHLPRFKVEESYDLKDTLRTMGMVDIFNGDADLS 315

Query: 308 GLTKMVDSPISQELYVSGIFQKSFIEVNEEGTKAAAVT--VSFISSRSRYSPPPPPPIDF 365
           G+T       S+ L +SG+  K+F+EV EEG +AAA T  V F SS      P     +F
Sbjct: 316 GMTG------SRGLVLSGVLHKAFVEVTEEGAEAAAATAVVGFGSS------PTSTNEEF 363

Query: 366 VADHPFLFLIREEFSGTILFVGKVVNP 392
             +HPFLF IR+  + +ILF G+  +P
Sbjct: 364 HCNHPFLFFIRQNKTNSILFYGRFSSP 390


>SPI2_HUMAN (O75830) Serpin I2 precursor (Myoepithelium-derived
           serine protease inhibitor) (Pancpin) (Protease inhibitor
           14) (TSA2004)
          Length = 405

 Score =  154 bits (389), Expect = 4e-37
 Identities = 108/372 (29%), Positives = 194/372 (52%), Gaps = 31/372 (8%)

Query: 31  EENVVFSPLSLNTVLSMIATGSEGPTQKQLLSFLQSEST--GDLKSLCSQLVSSVLSDGA 88
           ++N++FSPL +  VL M+  G++G  Q+Q+   L+ + T  G+   +     S++     
Sbjct: 42  KDNIIFSPLGITLVLEMVQLGAKGKAQQQIRQTLKQQETSAGEEFFVLKSFFSAISEKKQ 101

Query: 89  PAGGPCLSYVNGVWVEQTIPLQPSFKQLMNTDFKAAFAAVDFVNKANEVGEEVNFWAEKE 148
                  +  N +++++   ++  +       F++A   VDF + A    E ++ W E++
Sbjct: 102 EF---TFNLANALYLQEGFTVKEQYLHGNKEFFQSAIKLVDFQD-AKACAEMISTWVERK 157

Query: 149 TKGLIKNLLPPGSVNSLTRLIFANALYFKGVWKQQFDTTKTKDYDFDLLNGKSVKVPFM- 207
           T G IK++        LTRL+  NA+YFKG WKQ+F    T+  +F   NG +VK+P M 
Sbjct: 158 TDGKIKDMFSGEEFGPLTRLVLVNAIYFKGDWKQKFRKEDTQLINFTKKNGSTVKIPMMK 217

Query: 208 ---TSKNDQFISSLDGFKVLGLPYKQGKDERAFSIYFFLPDKKDGLSNLIDKVASDSEFL 264
               +K   F  S   ++VL L YK  +    FS+   LP +   +   ++K+ +  + L
Sbjct: 218 ALLRTKYGYFSESSLNYQVLELSYKGDE----FSLIIILPAEGMDIEE-VEKLITAQQIL 272

Query: 265 ERNLPRRKVEVGKFRIPRFNISFEIEASELLKKLGLALPFTLG-GLTKMVDSPISQELYV 323
           +     ++ EV +  +PRF +  +++  ++L  L +   F+ G  L+ + D   S E+YV
Sbjct: 273 KWLSEMQEEEV-EISLPRFKVEQKVDFKDVLYSLNITEIFSGGCDLSGITD---SSEVYV 328

Query: 324 SGIFQKSFIEVNEEGTKAAAVT---VSFISSRSRYSPPPPPPIDFVADHPFLFLIREEFS 380
           S + QK F E+NE+G++AA  T   +  I S ++          F+A+HPFLF+++   +
Sbjct: 329 SQVTQKVFFEINEDGSEAATSTGIHIPVIMSLAQ--------SQFIANHPFLFIMKHNPT 380

Query: 381 GTILFVGKVVNP 392
            +ILF+G+V NP
Sbjct: 381 ESILFMGRVTNP 392


>SPB8_HUMAN (P50452) Cytoplasmic antiproteinase 2 (CAP2) (CAP-2)
           (Protease inhibitor 8) (Serpin B8)
          Length = 374

 Score =  154 bits (389), Expect = 4e-37
 Identities = 115/371 (30%), Positives = 179/371 (47%), Gaps = 34/371 (9%)

Query: 33  NVVFSPLSLNTVLSMIATGSEGPTQKQLLSFLQSESTGDLKSLCSQLVSSVLSDGAPAGG 92
           NV FSP+S+++ L+M+  G++G T  Q+   L     GD+      L+S V   G     
Sbjct: 27  NVFFSPMSISSALAMVFMGAKGSTAAQMSQALCLYKDGDIHRGFQSLLSEVNRTGTQY-- 84

Query: 93  PCLSYVNGVWVEQTIPLQPSFKQLMNTDFKAAFAAVDFVNKANEVGEEVNFWAEKETKGL 152
             L   N ++ E+T    P FK+     ++A    + F     E  + +N W  ++T+G 
Sbjct: 85  -LLRTANRLFGEKTCDFLPDFKEYCQKFYQAELEELSFAEDTEECRKHINDWVAEKTEGK 143

Query: 153 IKNLLPPGSVNSLTRLIFANALYFKGVWKQQFDTTKTKDYDFDL-LNGKSVKVPFMTSKN 211
           I  +L  G+V+ LT+L+  NA+YFKG W +QFD   T+   F      K+V++ F  +K 
Sbjct: 144 ISEVLDAGTVDPLTKLVLVNAIYFKGKWNEQFDRKYTRGMLFKTNEEKKTVQMMFKEAKF 203

Query: 212 DQFISSLDGFKVLGLPYKQGKDERAFSIYFFLPDKKDGLSNLIDKVASDSEFL----ERN 267
               +     +VL LPY     E   S+   LPD    L+ +++K  +  +F        
Sbjct: 204 KMGYADEVHTQVLELPYV----EEELSMVILLPDDNTDLA-VVEKALTYEKFKAWTNSEK 258

Query: 268 LPRRKVEVGKFRIPRFNISFEIEASELLKKLGLALPF-----TLGGLTKMVDSPISQELY 322
           L + KV+V    +PR  +    +    L++LG+   F        G++   + P+S+   
Sbjct: 259 LTKSKVQV---FLPRLKLEESYDLEPFLRRLGMIDAFDEAKADFSGMSTEKNVPLSK--- 312

Query: 323 VSGIFQKSFIEVNEEGTKAAAVTVSFISSR-SRYSPPPPPPIDFVADHPFLFLIREEFSG 381
              +  K F+EVNEEGT+AAA T    +SR SR  P       F ADHPFLF IR   + 
Sbjct: 313 ---VAHKCFVEVNEEGTEAAAATAVVRNSRCSRMEP------RFCADHPFLFFIRRHKTN 363

Query: 382 TILFVGKVVNP 392
            ILF G+  +P
Sbjct: 364 CILFCGRFSSP 374


>SPB9_HUMAN (P50453) Cytoplasmic antiproteinase 3 (CAP3) (CAP-3)
           (Protease inhibitor 9) (Serpin B9)
          Length = 376

 Score =  150 bits (380), Expect = 4e-36
 Identities = 107/365 (29%), Positives = 180/365 (49%), Gaps = 20/365 (5%)

Query: 33  NVVFSPLSLNTVLSMIATGSEGPTQKQLLSFLQSESTGDLKSLCSQLVSSVLSDGAPAGG 92
           NV  SP+S+++ L+M+  G++G T  Q+   L   +  D+      L++ V   G     
Sbjct: 27  NVFCSPVSISSALAMVLLGAKGNTATQMAQALSLNTEEDIHRAFQSLLTEVNKAGTQY-- 84

Query: 93  PCLSYVNGVWVEQTIPLQPSFKQLMNTDFKAAFAAVDFVNKANEVGEEVNFWAEKETKGL 152
             L   N ++ E+T     +FK+     + A    + F+  A E  + +N W  K+T+G 
Sbjct: 85  -LLRTANRLFGEKTCQFLSTFKESCLQFYHAELKELSFIRAAEESRKHINTWVSKKTEGK 143

Query: 153 IKNLLPPGSVNSLTRLIFANALYFKGVWKQQFDTTKTKDYDFDLLNGKSVKVPFMTSKND 212
           I+ LLP  S+++ TRL+  NA+YFKG W + FD T T++  F +   +   V  M  +  
Sbjct: 144 IEELLPGSSIDAETRLVLVNAIYFKGKWNEPFDETYTREMPFKINQEEQRPVQMMYQEAT 203

Query: 213 QFISSLDGFK--VLGLPYKQGKDERAFSIYFFLPDKKDGLS-NLIDKVASDSEFLERNLP 269
             ++ +   +  +L LPY +    +  S+   LPD  DG+  + ++K  +  +      P
Sbjct: 204 FKLAHVGEVRAQLLELPYAR----KELSLLVLLPD--DGVELSTVEKSLTFEKLTAWTKP 257

Query: 270 --RRKVEVGKFRIPRFNISFEIEASELLKKLGLALPFTLGGLTKMVDSPISQELYVSGIF 327
              +  EV +  +P+F +  + +   +L+ LG+   F  G       S   ++L +S   
Sbjct: 258 DCMKSTEV-EVLLPKFKLQEDYDMESVLRHLGIVDAFQQGKADLSAMS-AERDLCLSKFV 315

Query: 328 QKSFIEVNEEGTKAAAVTVSFISSRSRYSPPPPPPIDFVADHPFLFLIREEFSGTILFVG 387
            KSF+EVNEEGT+AAA +  F+ +       P     F ADHPFLF IR   + +ILF G
Sbjct: 316 HKSFVEVNEEGTEAAAASSCFVVAECCMESGP----RFCADHPFLFFIRHNRANSILFCG 371

Query: 388 KVVNP 392
           +  +P
Sbjct: 372 RFSSP 376


>PTI6_BOVIN (O02739) Serine proteinase inhibitor B-43
          Length = 378

 Score =  150 bits (379), Expect = 5e-36
 Identities = 114/373 (30%), Positives = 186/373 (49%), Gaps = 31/373 (8%)

Query: 32  ENVVFSPLSLNTVLSMIATGSEGPTQKQLLSFLQ-SESTG---DLKSLCSQLVSSVLSDG 87
           +NV  SPLS+++ L+M+  G++G T  Q+   L  ++S+G   D+      L+S V    
Sbjct: 25  KNVFISPLSISSALAMVLLGAKGNTAAQMCQTLSLNKSSGGGEDVHQGFQNLLSEVNRRD 84

Query: 88  APAGGPCLSYVNGVWVEQTIPLQPSFKQLMNTDFKAAFAAVDFVNKANEVGEEVNFWAEK 147
                  L   N ++ E+T     SFK   +  ++A    +DFV+   +  + +N W  +
Sbjct: 85  TQY---LLRTANRLFGEKTYDFLSSFKDSCHKFYQAEMEELDFVSATEQSRKHINTWVAE 141

Query: 148 ETKGLIKNLLPPGSVNSLTRLIFANALYFKGVWKQQFDTTKTKDYDFDLLNGKSVKVPFM 207
           +T+G I++LLP  SVN +TRL+  NA+YFKG W  QF+   T++  F +       V  M
Sbjct: 142 KTEGKIRDLLPANSVNPMTRLVLVNAIYFKGNWDTQFNKEHTEERPFRVSKNVEKPVQMM 201

Query: 208 TSKNDQFISSLD--GFKVLGLPYKQGKDERAFSIYFFLPDKKDGLSNLIDKVASDSEFLE 265
             K+   I+ +     ++L LPY      +  ++   LP +   L N ++K  +  +F+ 
Sbjct: 202 FKKSTCKITYIGEISTQILVLPYV----GQELNMVILLPSESTDL-NTVEKALTYEKFIA 256

Query: 266 RNLP----RRKVEVGKFRIPRFNISFEIEASELLKKLGLALPF--TLGGLTKMVDSPISQ 319
              P      +VEV    +PRF +    +  E L++LG+   F  T    + M      +
Sbjct: 257 WTKPDVMDEEEVEV---FLPRFTLEESYDMEEFLQELGMTDAFEETRADFSGMSS---GR 310

Query: 320 ELYVSGIFQKSFIEVNEEGTKAAAVTVSFISSRSRYSPPPPPPIDFVADHPFLFLIREEF 379
            L++S +  KSF+EV EEGT+AAA T + +  R     P      F A+HPFLF I+   
Sbjct: 311 GLHLSKVMHKSFVEVTEEGTEAAAATGAVVMMRCLMVVP-----RFNANHPFLFFIQHSK 365

Query: 380 SGTILFVGKVVNP 392
           +G ILF G+  +P
Sbjct: 366 TGAILFCGRFCSP 378


>PAI1_RAT (P20961) Plasminogen activator inhibitor-1 precursor
           (PAI-1) (Endothelial plasminogen activator inhibitor)
           (PAI)
          Length = 402

 Score =  150 bits (379), Expect = 5e-36
 Identities = 122/401 (30%), Positives = 203/401 (50%), Gaps = 55/401 (13%)

Query: 13  TNISMNITKHLLSNQKLKEENVVFSPLSLNTVLSMIATGSEGPTQKQL---LSFLQSE-- 67
           TN  + + +H++  Q  K+ NVVFSP  +++VL+M+   + G T++Q+   + F  SE  
Sbjct: 36  TNFGVKVFQHVV--QASKDRNVVFSPYGVSSVLAMLQLTTAGKTRQQIQDAMGFNISERG 93

Query: 68  STGDLKSLCSQLVSSVLSDGAPAGGPCLSYVNGVWVEQTIPLQPSFKQLMNTDFKAAFAA 127
           +   L+ L  +L+ S   +        +S  + ++V++ + L   F       F+     
Sbjct: 94  TAPALRKLSKELMGSWNKNE-------ISTADAIFVQRDLELVQGFMPHFFKLFRTTVKQ 146

Query: 128 VDF--VNKANEVGEEVNFWAEKETKGLIKNLLPPGSVNSLTRLIFANALYFKGVWKQQFD 185
           VDF  V +A  +   +N W E+ TKG+I +LL  G+VN LTRL+  NALYF G WK  F 
Sbjct: 147 VDFSEVERARFI---INDWVERHTKGMISDLLAKGAVNELTRLVLVNALYFNGQWKTPFL 203

Query: 186 TTKTKDYDFDLLNGKSVKVPFMTSKNDQF----ISSLDG--FKVLGLPYKQGKDERAFSI 239
              T    F   +G ++ VP M ++N++F     ++ DG  + +L LPY         S+
Sbjct: 204 EASTHQRLFHKSDGSTISVPMM-AQNNKFNYTEFTTPDGHEYDILELPY----HGETLSM 258

Query: 240 YFFLPDKKDGLSNLIDKVASDSEFLER------NLPRRKVEVGKFRIPRFNISFEIEASE 293
           +   P +KD   + I  +  D+E + +       LPR  +      +P+F++  E++   
Sbjct: 259 FIAAPFEKDVPLSAITNIL-DAELIRQWKSNMTRLPRLLI------LPKFSLETEVDLRG 311

Query: 294 LLKKLGLALPF--TLGGLTKMVDSPISQELYVSGIFQKSFIEVNEEGTKAAAVTVSFISS 351
            L+KLG+   F  T    T + D    ++L V+   QK  IEVNE GT A++ T   +S+
Sbjct: 312 PLEKLGMTDIFSSTQADFTSLSD---QEQLSVAQALQKVKIEVNESGTVASSSTAILVSA 368

Query: 352 RSRYSPPPPPPIDFVADHPFLFLIREEFSGTILFVGKVVNP 392
           R         P + V D  FLF++R   + TILF+G+++ P
Sbjct: 369 RM-------APTEMVLDRSFLFVVRHNPTETILFMGQLMEP 402


  Database: sprot
    Posted date:  Nov 25, 2004 10:54 AM
  Number of letters in database: 59,974,054
  Number of sequences in database:  164,201
  
Lambda     K      H
   0.317    0.136    0.387 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 46,430,747
Number of Sequences: 164201
Number of extensions: 1976871
Number of successful extensions: 8251
Number of sequences better than 10.0: 164
Number of HSP's better than 10.0 without gapping: 143
Number of HSP's successfully gapped in prelim test: 22
Number of HSP's that attempted gapping in prelim test: 7668
Number of HSP's gapped (non-prelim): 186
length of query: 395
length of database: 59,974,054
effective HSP length: 112
effective length of query: 283
effective length of database: 41,583,542
effective search space: 11768142386
effective search space used: 11768142386
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 67 (30.4 bits)