BLAST2 result
BLASTP 2.2.2 [Dec-14-2001]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= AC122165.9 + phase: 0 /pseudo
(797 letters)
Database: sprot
164,201 sequences; 59,974,054 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
MST2_DROHY (Q08696) Axoneme-associated protein mst101(2) 125 6e-28
VG48_SHV21 (Q01033) Hypothetical gene 48 protein 118 7e-26
CYL2_BOVIN (Q28092) Cylicin II (Multiple-band polypeptide II) 113 2e-24
DEK_HUMAN (P35659) DEK protein 110 1e-23
CALD_CHICK (P12957) Caldesmon (CDM) 107 9e-23
NSB1_MOUSE (Q9JL35) Nucleosome binding protein 1 (Nucleosome bin... 103 2e-21
MDN1_YEAST (Q12019) Midasin (MIDAS-containing protein) 102 5e-21
NFM_MOUSE (P08553) Neurofilament triplet M protein (160 kDa neur... 99 4e-20
NFH_HUMAN (P12036) Neurofilament triplet H protein (200 kDa neur... 99 6e-20
GARP_PLAFF (P13816) Glutamic acid-rich protein precursor 99 6e-20
IF2P_HUMAN (O60841) Eukaryotic translation initiation factor 5B ... 98 8e-20
NFM_RAT (P12839) Neurofilament triplet M protein (160 kDa neurof... 97 1e-19
ATRX_CAEEL (Q9U7E0) Transcriptional regulator ATRX homolog (X-li... 96 4e-19
NFM_RABIT (P54938) Neurofilament triplet M protein (160 kDa neur... 96 5e-19
NFM_BOVIN (O77788) Neurofilament triplet M protein (160 kDa neur... 94 1e-18
NSB1_HUMAN (P82970) Nucleosomal binding protein 1 93 3e-18
CYL1_HUMAN (P35663) Cylicin I (Multiple-band polypeptide I) (Fra... 88 8e-17
TRDN_CANFA (P82179) Triadin 88 1e-16
IE68_SHV21 (Q01042) Immediate-early protein 87 1e-16
FUTS_DROME (Q9W596) Microtubule-associated protein futsch 87 2e-16
>MST2_DROHY (Q08696) Axoneme-associated protein mst101(2)
Length = 1391
Score = 125 bits (313), Expect = 6e-28
Identities = 162/681 (23%), Positives = 306/681 (44%), Gaps = 74/681 (10%)
Query: 8 DSSEKKDLEPKGGKIFEDNAVQDLKEDGIKAMEVDKKADGEEVLEMDKLADDGDVVTENA 67
+++E+K E I + + KE K E ++ EE+ + K A + E A
Sbjct: 424 EAAERKKCEELAKNIKKAAEKKKCKEAAKKEKEAAERKKCEELAKKIKKAAEKKKCEETA 483
Query: 68 IKAGDGEGIKEDEKVNE-GKEIKEDKQADEGEELKEDKKDNGGEERKEDKKVDVGQEVKE 126
K G+ + E +K E K+IK+ + + ++L + +K+ E++K +K +E E
Sbjct: 484 KK---GKEVAERKKCEELAKKIKKAEIKKKCKKLAKKEKET-AEKKKCEKAAKKRKEAAE 539
Query: 127 DKKVNEGGDIKEEKKADEGEKLKED--KKDDAAVKIKEDKKVNEGEELKEEKKADEGEKL 184
KK + K+ K+A E +K ++ K+ +AA K K +K E +E E+KK +E K
Sbjct: 540 KKKCEKAA--KKRKEAAEKKKCEKSAKKRKEAAEKKKCEKAAKERKEAAEKKKCEEAAKK 597
Query: 185 KEDKKDDAGVEIIEDKKVNEGEELEEEKKAEGEELKEDKKVDAGDEIEEDKKDDNGFEDD 244
+++ + E + KK+ + E ++ K+A +E + ++ G+ ++ KK +
Sbjct: 598 EKEVAERKKCEELA-KKIKKAAEKKKCKEAAKKEKEAAEREKCGELAKKIKKAAEKKKCK 656
Query: 245 KLSEETELSKEERESVEAKKPELDAMDEESILEG---KDEGSEKEKSQKDREDDKDKVDN 301
KL+++ + + E+++ +A K +A +++ E + E +EK+K ++ + +K+ +
Sbjct: 657 KLAKKEKETAEKKKCEKAAKKRKEAAEKKKCAEAAKKEKEAAEKKKCEEAAKKEKEAAER 716
Query: 302 KSNEENIK------VEKRLKKRGKGKVNGE---------NVKKKMKELKKIEDIPEAKDE 346
K EE K +K+ KK K K GE KK +KE KK ++ AK +
Sbjct: 717 KKCEELAKKIKKAAEKKKCKKLAKKKKAGEKNKLKKGNKKGKKALKEKKKCREL--AKKK 774
Query: 347 SIEKER-----SRDEEVGDKEKVGGENVKKKMKELKEAEPTTPTTNRPVRERKSVERLVE 401
+ EK++ +++E +K+K K+K + K+ T + E+K E+ +
Sbjct: 775 AAEKKKCKEAAKKEKEAAEKKKCEKTAKKRKEEAEKKKCEKTAKKRKEAAEKKKCEKAAK 834
Query: 402 SYDRDASK---EFQIEEGRGTPLKNIPNVAFKLSRRKVDDTLKFLHTILFCRRGKAAVIK 458
+A K E ++ + T K A K R++ + K C KAA +
Sbjct: 835 KRKEEAEKKKCEKTAKKRKETAEKKKCEKAAK-KRKQAAEKKK-------CE--KAAKKR 884
Query: 459 KNILRFSGFVWHENEEKQMIKVKEKFDKCNKEKLLEFSDLLDVPVGNANTRKEDIIAKLI 518
K +EK++ + K+ + KEK + A +K + +AK I
Sbjct: 885 KEAAEKKKCAEAAKKEKELAEKKKCEEAAKKEKEV------------AERKKCEELAKKI 932
Query: 519 DFLVAPQVTKSVLLAEQEKSAKEKRIAKQGSTGSGTPTSRRSAKSRKKIEDSSIAEKKKT 578
A + K LA++EK A EK K+ G G ++ K K+ AEKKK
Sbjct: 933 K--KAAEKKKCKKLAKKEKKAGEKNKLKK-KAGKGKKKCKKLGKKSKR-----AAEKKKC 984
Query: 579 ATDTESESE----KDEENKEENEIDVSDKSEDEKPIKGKKHIAKQGSSRSGTASSRRSAK 634
A + E E K E + + + + ++K + E+ K K A+Q + +A+
Sbjct: 985 AEAAKKEKEAATKKKCEERAKKQKEAAEKKQCEERAKKLKEAAEQKQCEERAKKLKEAAE 1044
Query: 635 E*NIFQKERIRCTKQSKESNR 655
+ +ER + K++ E +
Sbjct: 1045 KKQC--EERAKKLKEAAEQKQ 1063
Score = 117 bits (294), Expect = 9e-26
Identities = 203/834 (24%), Positives = 354/834 (42%), Gaps = 102/834 (12%)
Query: 8 DSSEKKDLEPKGGKIFEDNAVQDLKEDGIKAMEVDKKADGEEVLEMDKLADDGDVVTENA 67
+++EKK E + E + +E K EV ++ EE+ + K A + E A
Sbjct: 568 EAAEKKKCEKAAKERKEAAEKKKCEEAAKKEKEVAERKKCEELAKKIKKAAEKKKCKEAA 627
Query: 68 IKAGDGEGIKEDEKVNE-GKEIKEDKQADEGEELKEDKKDNGGEERKEDKKVDVGQEVKE 126
K + E EK E K+IK+ + + ++L + +K+ E++K +K +E E
Sbjct: 628 KKEKEAA---EREKCGELAKKIKKAAEKKKCKKLAKKEKETA-EKKKCEKAAKKRKEAAE 683
Query: 127 DKKVNEGGDIKEEKKADEGEKLKEDKK-----------DDAAVKIKEDKKVNEGEELKEE 175
KK E K+EK+A E +K +E K ++ A KIK+ + + ++L ++
Sbjct: 684 KKKCAEAA--KKEKEAAEKKKCEEAAKKEKEAAERKKCEELAKKIKKAAEKKKCKKLAKK 741
Query: 176 KKADEGEKLKEDKKDDAGVEIIEDKKVNEGEELEEEKKAEGEELKEDKKVDAGDEIEEDK 235
KKA E KLK+ K G + +++KK + EL ++K AE ++ KE K + E E K
Sbjct: 742 KKAGEKNKLKKGNKK--GKKALKEKK--KCRELAKKKAAEKKKCKEAAKKEK--EAAEKK 795
Query: 236 KDDNGFEDDKLSEETELSKEERESVEAKKPELDAMDEESILEGKDEGSEK--EKSQKDRE 293
K + + K EE E K E+ + + K+ E++ + K+E +K EK+ K R+
Sbjct: 796 KCEKTAK--KRKEEAEKKKCEKTAKKRKEAAEKKKCEKAAKKRKEEAEKKKCEKTAKKRK 853
Query: 294 DDKDKVD-------NKSNEENIKVEKRLKKRGKG--KVNGENVKKKMKELKKIEDIPEA- 343
+ +K K E K EK KKR + K KK KEL + + EA
Sbjct: 854 ETAEKKKCEKAAKKRKQAAEKKKCEKAAKKRKEAAEKKKCAEAAKKEKELAEKKKCEEAA 913
Query: 344 KDESIEKERSRDEEVGDKEKVGGENVKKKMKELKEAEPTTPTTNRPVRE----RKSVERL 399
K E ER + EE+ K K E KKK K+L + E N+ ++ +K ++L
Sbjct: 914 KKEKEVAERKKCEELAKKIKKAAE--KKKCKKLAKKEKKAGEKNKLKKKAGKGKKKCKKL 971
Query: 400 VESYDRDASK----EFQIEEGRGTPLKNIPNVAFK----LSRRKVDDTLKFLHTILF--- 448
+ R A K E +E K A K +++ ++ K L
Sbjct: 972 GKKSKRAAEKKKCAEAAKKEKEAATKKKCEERAKKQKEAAEKKQCEERAKKLKEAAEQKQ 1031
Query: 449 ----CRRGKAAVIKKNILRFSGFVWHENEEKQMIKVKEKFDKCNKEKLLEFSDLLDVPVG 504
++ K A KK + + E+KQ + +K + ++K E
Sbjct: 1032 CEERAKKLKEAAEKKQCEERAKKLKEAAEQKQCEERAKKLKEAAEKKQCE---------E 1082
Query: 505 NANTRKEDIIAKLIDFLVAPQVTKSVLLAEQEKSAKEKRIAKQGSTGSGTPTSRRSAKSR 564
A KE K + A ++ ++ + E+ AK+++ A + + A +
Sbjct: 1083 RAKKEKEAAEKKQCEER-AKKLKEAAEKKQCEERAKKEKEAAEKKRCEEAAKREKEAAEK 1141
Query: 565 KKIEDSSIAEKKKTATDTESESEKDEENKEENEIDVSDKSEDEKPIKGKKHIAKQGSSRS 624
KK +++ EK+ T +E+ K E+ E + ++ ++ EK KK A
Sbjct: 1142 KKCAEAAKKEKEATEKQKCAEAAKKEKEAAEKK-KCAEAAKREKEAAQKKKCADLAKKEQ 1200
Query: 625 GTASSRR----SAKE*NIFQKER-IRCTKQSKESNR*NKTSLGTKANF*EAIVYTLCI*S 679
A ++ + KE +K++ + K+ KE+ K + K EA C
Sbjct: 1201 EPAEMKKCEEAAKKEKEAAEKQKCAKAAKKEKEAAEKKKCAEAAKKEQ-EAAEKKKC--- 1256
Query: 680 W***WKSQGLFKEEEK*KTRKAEDLNSHQVFLQRQSRKIKNKEKSDPSDDQLRKAICVIF 739
++ KE+E K RK E L+RQ K+ + K + LRK +I
Sbjct: 1257 ------AEAAKKEKEAEKKRKCEKAEK-AAALKRQCAKLVIRAK----EAALRKKCAIIA 1305
Query: 740 KKVDFNTATFADILKLLGKQFDVDLTPRKASVKTIIQQELAKLAEEDEEREQRE 793
KK K+ ++ + + +KA + I ++ AKLA++ E E+++
Sbjct: 1306 KKA-----------KMAAEKKECEKLAKKAK-EAIEWKKCAKLAKKKREAEKKK 1347
Score = 117 bits (293), Expect = 1e-25
Identities = 170/688 (24%), Positives = 290/688 (41%), Gaps = 86/688 (12%)
Query: 12 KKDLEPKGGKIFEDNAVQDLKEDGIKAMEVDKKADGEEVLEMDKLADDGDVVTENAIKAG 71
KK + G K+ E+ + K E D+K +E+ + K AD+ E A K
Sbjct: 332 KKKCKDLGRKMKEEAEKKKCAALAKKQKEEDEKKACKELAKKKKEADEKKKCEEAANKEK 391
Query: 72 DGEGIKEDEK-VNEGKEIKEDKQADEGEELKEDKKDNGGEERKEDKKVDVG-QEVKEDKK 129
K+ EK E KE E K+ +E KK+ ERK+ +++ ++ E KK
Sbjct: 392 KAAEKKKCEKAAKERKEAAEKKKCEEAA-----KKEKEAAERKKCEELAKNIKKAAEKKK 446
Query: 130 VNEGGDIKEEKKADEGEKLKE--DKKDDAAVKIKEDKKVNEGEELKEEKKADE-GEKLKE 186
E K+EK+A E +K +E K AA K K ++ +G+E+ E KK +E +K+K+
Sbjct: 447 CKEAA--KKEKEAAERKKCEELAKKIKKAAEKKKCEETAKKGKEVAERKKCEELAKKIKK 504
Query: 187 -------DKKDDAGVEIIEDKKVNEGEELEEEKKAEGEELKEDKKVDAGDEIEEDKKDDN 239
K E E KK E+ +++K E+ K +K E E KK +
Sbjct: 505 AEIKKKCKKLAKKEKETAEKKKC---EKAAKKRKEAAEKKKCEKAAKKRKEAAEKKKCEK 561
Query: 240 GFEDDKLSEE----TELSKEERESVEAKKPELDAMDEESILEGKDEGSEKEKSQKDREDD 295
+ K + E + +KE +E+ E KK E A E+ + E K +K +K E
Sbjct: 562 SAKKRKEAAEKKKCEKAAKERKEAAEKKKCEEAAKKEKEVAERKKCEELAKKIKKAAEKK 621
Query: 296 KDKVDNKSNEENIKVE------KRLKKRGKGKVNGENVKKKMK--ELKKIEDIPEAKDES 347
K K K +E + E K++KK + K + KK+ + E KK E + + E+
Sbjct: 622 KCKEAAKKEKEAAEREKCGELAKKIKKAAEKKKCKKLAKKEKETAEKKKCEKAAKKRKEA 681
Query: 348 IEKER-----SRDEEVGDKEKVGGENVKKKMKELKEAEPTTPTTN--RPVRERKSVERLV 400
EK++ +++E +K+K E KK KE E + + E+K ++L
Sbjct: 682 AEKKKCAEAAKKEKEAAEKKKC--EEAAKKEKEAAERKKCEELAKKIKKAAEKKKCKKLA 739
Query: 401 ESYDRDASKEFQIEEGRGTPLKNIPNVAFKLSRRKVDDTLKFLHTILFCRRGKAAVIKKN 460
+ + + +G +L+++K + K ++ K A KK
Sbjct: 740 KKKKAGEKNKLKKGNKKGKKALKEKKKCRELAKKKAAEKKKCKEA---AKKEKEAAEKKK 796
Query: 461 ILRFSGFVWHENEEKQMIKVKEKFDKCNKEKLLEFSDLLDVPVGNANTRKEDIIAKLIDF 520
+ + E E+K+ K +K + ++K E + A RKE+ K
Sbjct: 797 CEKTAKKRKEEAEKKKCEKTAKKRKEAAEKKKCEKA---------AKKRKEEAEKK---- 843
Query: 521 LVAPQVTKSVLLAEQEKSAKEKRIAKQGSTGSGTPTSRRSAKSRKKIEDSS-----IAEK 575
+ EK+AK+++ + R+ A +KK E ++ AEK
Sbjct: 844 -------------KCEKTAKKRKETAEKKKCEKAAKKRKQAAEKKKCEKAAKKRKEAAEK 890
Query: 576 KKTATDTESESEKDEENKEE----NEIDVSDKSEDEKPIKGKKHIAKQGSSRSGTASSRR 631
KK A + E E E+ K E E +V+++ + E+ K K A++ + A +
Sbjct: 891 KKCAEAAKKEKELAEKKKCEEAAKKEKEVAERKKCEELAKKIKKAAEKKKCKK-LAKKEK 949
Query: 632 SAKE*NIFQKE----RIRCTKQSKESNR 655
A E N +K+ + +C K K+S R
Sbjct: 950 KAGEKNKLKKKAGKGKKKCKKLGKKSKR 977
Score = 112 bits (280), Expect = 4e-24
Identities = 160/660 (24%), Positives = 279/660 (42%), Gaps = 82/660 (12%)
Query: 29 QDLKEDGIKAMEVDKKADGEEVLEMDKLADDGDVVTENAIKAGDGEGIKEDEKVNEGKEI 88
Q+ ED K + K G ++ + + V+ E AG +K E +GK+
Sbjct: 238 QNFTEDERKRLAASYKCMGTKIKSICRKR----VIAEMCEAAGY---VKSSEPKKKGKKK 290
Query: 89 KEDKQADEGEELKEDKKDNGGEERKEDKKVDVGQEVKEDKKVNEGGDIKEEKKADEGEKL 148
K D++ ++ E +E K+ EE K + VKE KK + +K++ K D G K+
Sbjct: 291 KNDEKKEKELE-REILKEQAEEEAK------IRGVVKEVKKKCKEKALKKKCK-DLGRKM 342
Query: 149 KED--KKDDAAVKIK---EDKKVNEGEELKEEKKADEGEKLKE--DKKDDAGVEIIEDKK 201
KE+ KK AA+ K ED+K E K++K+ADE +K +E +K+ A + +K
Sbjct: 343 KEEAEKKKCAALAKKQKEEDEKKACKELAKKKKEADEKKKCEEAANKEKKAAEKKKCEKA 402
Query: 202 VNEGEELEEEKKAEGEELKEDKKVDAGDEIEEDKKDDNGFEDDKLSEETELSKEERESVE 261
E +E E+KK E E K++K+ + EE K+ + K +E +K+E+E+ E
Sbjct: 403 AKERKEAAEKKKCE-EAAKKEKEAAERKKCEELAKNIKKAAEKKKCKEA--AKKEKEAAE 459
Query: 262 AKKPELDAMDEESILEGKDEGSEKEKSQKDREDDKDKVDNKSNEENIK------VEKRLK 315
KK E + + + +EK+K ++ + K+ + K EE K ++K+ K
Sbjct: 460 RKKCE-------ELAKKIKKAAEKKKCEETAKKGKEVAERKKCEELAKKIKKAEIKKKCK 512
Query: 316 KRGKGKVNGENVKKKMKELKKIEDIPEAKDESIEKERSRDEEVGDKEKVGGENVKKK--- 372
K K + KK K KK ++ E K EK + +E +K+K K+K
Sbjct: 513 KLAKKEKETAEKKKCEKAAKKRKEAAEKK--KCEKAAKKRKEAAEKKKCEKSAKKRKEAA 570
Query: 373 --------MKELKEAE-----PTTPTTNRPVRERKSVERLVESYDRDAS----KEFQIEE 415
KE KEA + V ERK E L + + A KE +E
Sbjct: 571 EKKKCEKAAKERKEAAEKKKCEEAAKKEKEVAERKKCEELAKKIKKAAEKKKCKEAAKKE 630
Query: 416 GRGTPLKNIPNVAFKLSRRKVDDTLKFLHTILFCRRGKAAVIKKNILRFSGFVWHENEEK 475
+ +A K+ + K L ++ K KK + + E+K
Sbjct: 631 KEAAEREKCGELAKKIKKAAEKKKCKKL-----AKKEKETAEKKKCEKAAKKRKEAAEKK 685
Query: 476 QMIKVKEKFDKCNKEKLLEFSDLLDVPVGNANTRKEDIIAKLIDFLVAPQVTKSVLLAEQ 535
+ + +K + ++K E + A KE K + L A ++ K+ +
Sbjct: 686 KCAEAAKKEKEAAEKKKCEEA---------AKKEKEAAERKKCEEL-AKKIKKAAEKKKC 735
Query: 536 EKSAKEKRIAKQGSTGSGTPTSRRSAKSRKKIED---SSIAEKKKTATDTESESEKDEEN 592
+K AK+K+ ++ G +++ K +KK + AEKKK + E E E+
Sbjct: 736 KKLAKKKKAGEKNKLKKGNKKGKKALKEKKKCRELAKKKAAEKKKCKEAAKKEKEAAEKK 795
Query: 593 KEENEIDVSDKSEDEKPIKGKKHIAKQGSSRSGTASSRRSAKE*NIFQKERIRCTKQSKE 652
K E + ++K + K+ + + + + KE + E+ +C K +K+
Sbjct: 796 KCEKTAKKRKEEAEKKKCEKTAKKRKEAAEKKKCEKAAKKRKE----EAEKKKCEKTAKK 851
Score = 95.9 bits (237), Expect = 4e-19
Identities = 143/626 (22%), Positives = 259/626 (40%), Gaps = 65/626 (10%)
Query: 9 SSEKKDLEPKGGKIFEDNAVQDLKEDGIKAMEVDKKADGEEVLEMDKLADDGDVVTENAI 68
++EKK + K E + ++ K E +K E+ + K A + + A
Sbjct: 775 AAEKKKCKEAAKKEKEAAEKKKCEKTAKKRKEEAEKKKCEKTAKKRKEAAEKKKCEKAAK 834
Query: 69 KAGDGEGIKEDEKV-NEGKEIKEDKQADEGEELKEDKKDNGGEERKEDKKVDVGQEVKED 127
K + K+ EK + KE E K+ ++ + K+ E++K +K +E E
Sbjct: 835 KRKEEAEKKKCEKTAKKRKETAEKKKCEKAAK----KRKQAAEKKKCEKAAKKRKEAAEK 890
Query: 128 KKVNEGG----DIKEEKKADEGEKLKED-----KKDDAAVKIKEDKKVNEGEEL-KEEKK 177
KK E ++ E+KK +E K +++ K ++ A KIK+ + + ++L K+EKK
Sbjct: 891 KKCAEAAKKEKELAEKKKCEEAAKKEKEVAERKKCEELAKKIKKAAEKKKCKKLAKKEKK 950
Query: 178 ADEGEKLKEDKKDDAGVEIIEDKKVNEGEELEEEKKAEGEELKEDKKVDAGDEIEEDKKD 237
A E KLK+ AG + KK+ + + EKK E K++K+ + EE K
Sbjct: 951 AGEKNKLKKK----AGKGKKKCKKLGKKSKRAAEKKKCAEAAKKEKEAATKKKCEERAKK 1006
Query: 238 DNGFEDDKLSEETELSKEERESVEAKKPELDAMDEESILEGKD---------EGSEKEKS 288
+ K EE +K+ +E+ E K+ E A + E K E +E+++
Sbjct: 1007 QKEAAEKKQCEER--AKKLKEAAEQKQCEERAKKLKEAAEKKQCEERAKKLKEAAEQKQC 1064
Query: 289 QKDREDDKDKVDNKSNEENIKVEKRLKKRGKGKVNGENVKKKMKELKKIEDIPE-AKDES 347
++ + K+ + K EE K EK + K E KK+KE + + E AK E
Sbjct: 1065 EERAKKLKEAAEKKQCEERAKKEKEAAE----KKQCEERAKKLKEAAEKKQCEERAKKEK 1120
Query: 348 IEKERSRDEEVGDKEKVGGENVK-----KKMKELKEAEPTTPTTNRP--VRERK----SV 396
E+ R EE +EK E K KK KE E + + E+K +
Sbjct: 1121 EAAEKKRCEEAAKREKEAAEKKKCAEAAKKEKEATEKQKCAEAAKKEKEAAEKKKCAEAA 1180
Query: 397 ERLVESYDRDASKEFQIEEGRGTPLKNIPNVAFKLSRRKVDDTLKFLHTILFCRRGKAAV 456
+R E+ + + +E +K A +K + + ++ K A
Sbjct: 1181 KREKEAAQKKKCADLAKKEQEPAEMKKCEEAA-----KKEKEAAEKQKCAKAAKKEKEAA 1235
Query: 457 IKKNILRFSGFVWHENEEKQMIKVKEKFDKCNKEKLLEFSDLLDVPVGNANTRKEDIIAK 516
KK + E+K+ + +K + K++ E ++ A K
Sbjct: 1236 EKKKCAEAAKKEQEAAEKKKCAEAAKKEKEAEKKRKCEKAE-------KAAALKRQCAKL 1288
Query: 517 LIDFLVAPQVTKSVLLAEQEKSAKEKR----IAKQGSTGSGTPTSRRSAKSRKKIED--- 569
+I A K ++A++ K A EK+ +AK+ + AK +++ E
Sbjct: 1289 VIRAKEAALRKKCAIIAKKAKMAAEKKECEKLAKKAKEAIEWKKCAKLAKKKREAEKKKC 1348
Query: 570 SSIAEKKKTATDTESESEKDEENKEE 595
+ +A+K+K A + + + +NK++
Sbjct: 1349 AKLAKKEKEAAEKKKRCKDLAKNKKK 1374
Score = 73.6 bits (179), Expect = 2e-12
Identities = 88/354 (24%), Positives = 161/354 (44%), Gaps = 33/354 (9%)
Query: 6 LDDSSEKKDLEPKGGKIFEDNAVQDLKEDGIKAMEVDKKADGEEVLEMDKLADDGDVVTE 65
L +++EKK E + K+ E + +E K E +K EE + +K A + E
Sbjct: 1039 LKEAAEKKQCEERAKKLKEAAEQKQCEERAKKLKEAAEKKQCEERAKKEKEAAEKKQCEE 1098
Query: 66 NAIKAGDGEGIKE-DEKVNEGKEIKEDKQADEGEELKED--KKDNGGEERKEDKKVDVGQ 122
A K + K+ +E+ + KE E K+ +E + +++ +K E K++K+ Q
Sbjct: 1099 RAKKLKEAAEKKQCEERAKKEKEAAEKKRCEEAAKREKEAAEKKKCAEAAKKEKEATEKQ 1158
Query: 123 EVKED-KKVNEGGDIKEEKKADEGEKLKEDKKD--DAAVKIKEDKKVNEGEEL-KEEKKA 178
+ E KK E + K+ +A + EK KK D A K +E ++ + EE K+EK+A
Sbjct: 1159 KCAEAAKKEKEAAEKKKCAEAAKREKEAAQKKKCADLAKKEQEPAEMKKCEEAAKKEKEA 1218
Query: 179 DEGEKLKEDKKDDAGVEIIEDKKVNEGEELEEE---KKAEGEELKEDKKVDAGDEIEEDK 235
E +K + K + E E KK E + E+E KK E K++K+ + + E+ +
Sbjct: 1219 AEKQKCAKAAKKEK--EAAEKKKCAEAAKKEQEAAEKKKCAEAAKKEKEAEKKRKCEKAE 1276
Query: 236 KDDNGFEDDK-----------------LSEETELSKEERESVEAKKPELDAMDEESI--L 276
K ++++ +++ E++E + K +A++ + L
Sbjct: 1277 KAAALKRQCAKLVIRAKEAALRKKCAIIAKKAKMAAEKKECEKLAKKAKEAIEWKKCAKL 1336
Query: 277 EGKDEGSEKEKSQKDREDDKDKVDNKSNEENIKVEKRLKKRGKGKVNGENVKKK 330
K +EK+K K + +K+ + K +++ K KK K K EN KK+
Sbjct: 1337 AKKKREAEKKKCAKLAKKEKEAAEKKKRCKDLAKNK--KKGHKKKGRNENRKKR 1388
Score = 50.1 bits (118), Expect = 2e-05
Identities = 157/715 (21%), Positives = 282/715 (38%), Gaps = 129/715 (18%)
Query: 149 KEDKKDDAAVKIKEDKKVNEGEELKEEKKADEGEKLKEDKKDDAGVEIIEDKKVNEGEEL 208
K + DD+ +I+ D ++ K+++K +E K++E K++ V+ K+V L
Sbjct: 48 KNESTDDSN-QIRCDADKTAADKKKQKQKEEEQAKIREYKRECLKVQ----KRV-----L 97
Query: 209 EEEKKAEGEELKEDKKVDAGDEIEED--KKDDNGFEDDKLSEETELSKEERESVEAKKPE 266
EE + GE K+ + + D KK KL + EL+ + + +KK +
Sbjct: 98 AEEIRCSGE--KDRILIQGMMKCLTDGMKKACTKIAKAKLIADKELAVQC--AALSKKDK 153
Query: 267 LDAMDEESILEGKDEGSEKEKSQKDREDDKDKVDNKSNEENIKVEKRLKKRGKGKVNGEN 326
+ A+ ++ +RE K+K N+++ ++ K + KGK G N
Sbjct: 154 VKALLKKC----------------EREKSKEKECNQNSPAEGDKDRTKKGKTKGKSGGGN 197
Query: 327 VKKKMKE--------------LKKIE--------DIPEAKDESIEKERSRDEEVGDKEKV 364
K+ KE +K+E D+ E + E ER R + K
Sbjct: 198 KKRSTKENRAKKGKKLVKNRFTQKLEHCIKSEWADVCECRQNFTEDERKR---LAASYKC 254
Query: 365 GGENV-----KKKMKELKEAEPTTPTT--NRPVRERKSVERLVESYDRDASKEFQIEEGR 417
G + K+ + E+ EA ++ + +++K+ E+ + +R+ KE EE +
Sbjct: 255 MGTKIKSICRKRVIAEMCEAAGYVKSSEPKKKGKKKKNDEKKEKELEREILKEQAEEEAK 314
Query: 418 GTPLKNIPNVAFKLSRRKVDDTLKFLHTILFCRRGKAAVIKKNILRFSGFVWHENEE--- 474
I V ++ ++ + LK L R+ K KK + E+E+
Sbjct: 315 ------IRGVVKEVKKKCKEKALKKKCKDL-GRKMKEEAEKKKCAALAKKQKEEDEKKAC 367
Query: 475 KQMIKVKEKFD---KC----NKEKLLEFSDLLDVPVGNANTRKEDIIAKLIDFLV----- 522
K++ K K++ D KC NKEK + A RKE K +
Sbjct: 368 KELAKKKKEADEKKKCEEAANKEKKAAEKKKCEKA---AKERKEAAEKKKCEEAAKKEKE 424
Query: 523 APQVTKSVLLAEQEKSAKEKRIAKQGSTGSGTPTSR----------RSAKSRKKIEDSS- 571
A + K LA+ K A EK+ K+ + R + A +KK E+++
Sbjct: 425 AAERKKCEELAKNIKKAAEKKKCKEAAKKEKEAAERKKCEELAKKIKKAAEKKKCEETAK 484
Query: 572 ----IAEKKK----TATDTESESEKDEENKEENEIDVSDKSEDEKPIKGKKHIAKQGSSR 623
+AE+KK ++E +K + + E + ++K + EK K +K A++
Sbjct: 485 KGKEVAERKKCEELAKKIKKAEIKKKCKKLAKKEKETAEKKKCEKAAKKRKEAAEKKKCE 544
Query: 624 SGTASSRRSAKE*NIFQKERIRCTKQSKESNR*NKTSLGTKANF*EAIVYTLCI*SW*** 683
A R+ A E +K+ + K+ KE+ K K EA C
Sbjct: 545 K-AAKKRKEAAE----KKKCEKSAKKRKEAAEKKKCEKAAKERK-EAAEKKKC------- 591
Query: 684 WKSQGLFKEEEK*KTRKAEDLNSHQVFLQRQSRKIKNKEKSDPSDDQLRKAICVIFKKVD 743
+ KE+E + +K E+L +++ + K K KE + + + C K
Sbjct: 592 --EEAAKKEKEVAERKKCEELAKK---IKKAAEKKKCKEAAKKEKEAAEREKCGELAKKI 646
Query: 744 FNTATFADILKLLGKQFDVDLTPR--KASVKTIIQQELAKLAE-EDEEREQRERR 795
A KL K+ + + KA+ K E K AE +E+E E++
Sbjct: 647 KKAAEKKKCKKLAKKEKETAEKKKCEKAAKKRKEAAEKKKCAEAAKKEKEAAEKK 701
>VG48_SHV21 (Q01033) Hypothetical gene 48 protein
Length = 797
Score = 118 bits (295), Expect = 7e-26
Identities = 116/368 (31%), Positives = 181/368 (48%), Gaps = 56/368 (15%)
Query: 6 LDDSSEKKDLEPKGGKIFEDNAVQDLKEDGIKAMEVDKKADGEEVLEMDKLADDGDVVTE 65
L++ +D E G+ ED +D KE+G D+ DGE+ E D+ D+GD E
Sbjct: 407 LENEEYNRDEEEDEGEDEEDE--KDEKEEG-----EDEGDDGEDEGE-DEGEDEGDEGDE 458
Query: 66 NAIKAGDGEGIKEDEKVNEGKEIKEDKQADEGEELKEDKKDNGGEERKE-DKKVDVGQEV 124
G+ EG ED++ +EG++ E + DEGE+ + D+ D G +E E D+ D G E
Sbjct: 459 G--DEGEDEGEDEDDEEDEGED--EGDEGDEGED-EGDEGDEGEDEGDEGDEGKDEGDEG 513
Query: 125 KEDKKVNEGGDIKEEKKADEGEKLKEDKKDDAAVKIKEDKKVNEGEELKEEKKADEGEKL 184
E K + GD E + DEGE ED+ D+ +EG+E ++E DEGE
Sbjct: 514 DEGKDEGDEGD--EGDEGDEGEDEWEDEGDEGE---------DEGDEGEDE--GDEGEDE 560
Query: 185 KEDKKDDAGVEIIEDKKVNEGEELEEEKKAEGEELKEDKKVDAGDEIEEDKKDDNGFEDD 244
ED+ D+ ED+ +EG+E E+E + EG+E ED+ D GDE ED+ +D G E D
Sbjct: 561 GEDEGDEG-----EDEGEDEGDEGEDEGEDEGDE-GEDEGEDEGDE-GEDEGEDEGDEGD 613
Query: 245 KLSEETELSKEERESVEAKKPELDAMDEESILEGKDEGSEKEKSQKDREDDKDKVDNKSN 304
+ +E + ++E + E DE EG+DEG E E + ED+ D+ +++ +
Sbjct: 614 EGEDEGDEGEDEGDEGE---------DEGD--EGEDEGDEGEDEGDEGEDEGDEGEDEGD 662
Query: 305 EENIKVEKRLKKRGKGKVNGENVKKKMKELKKIEDIPEAKDESIEKERSRDEEVGDKEKV 364
E + +G+ G+ + + E + D + DE E + DE + E
Sbjct: 663 EGD-----------EGEDEGDEGEDEGDEGEDEGDEGDEGDEGDEGDEGEDEGEDEGEDE 711
Query: 365 GGENVKKK 372
G E K K
Sbjct: 712 GDEGTKDK 719
Score = 109 bits (273), Expect = 2e-23
Identities = 92/339 (27%), Positives = 178/339 (52%), Gaps = 13/339 (3%)
Query: 37 KAMEVDKKADGEEVLEMDKLADDGDVVTENAIKAGDGEGIKEDEKVNEGKEIKEDKQA-- 94
+ + VDK+A+ +E ++ +DD D ++ + + E DE+ +EG++ +++K
Sbjct: 374 QVLTVDKQANEKEYKKIIDKSDDRDDRDKDEYEL-ENEEYNRDEEEDEGEDEEDEKDEKE 432
Query: 95 ---DEGEELKEDKKDNGGEERKEDKKVDVGQEVKEDKKVNEGGDIKEEKKADEGEKLKED 151
DEG++ +++ +D G +E E + D G++ ED+ E E + DEGE ++
Sbjct: 433 EGEDEGDDGEDEGEDEGEDEGDEGDEGDEGEDEGEDEDDEEDEGEDEGDEGDEGEDEGDE 492
Query: 152 KKDDAAVKIKEDKKVNEGEELKEEKKADEGEKLKEDKKDDAGVEIIEDKKVNEGEELEEE 211
+ + D+ +EG+E E K DEG++ E + D G + ED+ +EGE+ +E
Sbjct: 493 GDEGEDEGDEGDEGKDEGDEGDEGK--DEGDEGDEGDEGDEGEDEWEDEG-DEGEDEGDE 549
Query: 212 KKAEGEELKEDKKVDAGDEIEEDKKDDNGFEDDKLSEETELSKEERESVEAKKPELDAMD 271
+ EG+E ED+ D GDE E++ +D+ +D+ +E + ++E E E + E + D
Sbjct: 550 GEDEGDE-GEDEGEDEGDEGEDEGEDEGDEGEDEGEDEGDEGEDEGED-EGDEGEDEGED 607
Query: 272 E-ESILEGKDEGSEKEKSQKDREDDKDKVDNKSNEENIKVEKRLKKRGKGKVNGENVKKK 330
E + EG+DEG E E + ED+ D+ +++ +E + ++ + +G+ G+ +
Sbjct: 608 EGDEGDEGEDEGDEGEDEGDEGEDEGDEGEDEGDEGEDEGDEGEDEGDEGEDEGDEGDEG 667
Query: 331 MKELKKIEDI-PEAKDESIEKERSRDEEVGDKEKVGGEN 368
E + ED E +DE E + + + GD+ + GE+
Sbjct: 668 EDEGDEGEDEGDEGEDEGDEGDEGDEGDEGDEGEDEGED 706
Score = 104 bits (259), Expect = 1e-21
Identities = 106/317 (33%), Positives = 167/317 (52%), Gaps = 40/317 (12%)
Query: 7 DDSSEKKDLEPKGGKIFEDNAVQDLKEDGIKAMEVDKKADG--EEVLEMDKLADDGDVVT 64
D+ EK++ E +G ED + +++G + E D+ D +E E D+ D+GD
Sbjct: 426 DEKDEKEEGEDEGDD-GEDEGEDEGEDEGDEGDEGDEGEDEGEDEDDEEDEGEDEGDEGD 484
Query: 65 ENAIKAGDGEGIKEDEKVNEGKEIKEDKQADEGEELKEDKKDNGGEERKEDKKVDVGQEV 124
E G+ EG + DE +EG E E K DEG+E E K + G+E E + D G++
Sbjct: 485 E-----GEDEGDEGDEGEDEGDEGDEGK--DEGDEGDEGKDE--GDEGDEGDEGDEGEDE 535
Query: 125 KEDKKVNEGGDIKEE--KKADEGEKLKEDKKDDAAVKIKEDKKVNEGEELKEE--KKADE 180
ED+ +EG D +E + DEGE ED+ D+ ED+ +EG+E ++E + DE
Sbjct: 536 WEDEG-DEGEDEGDEGEDEGDEGEDEGEDEGDEG-----EDEGEDEGDEGEDEGEDEGDE 589
Query: 181 GEKLKEDKKD-------DAGVEIIE-DKKVNEGEELEEEKKAEGEELKE--DKKVDAGDE 230
GE ED+ D D G E E + + +EGE+ +E + EG+E ++ D+ D GDE
Sbjct: 590 GEDEGEDEGDEGEDEGEDEGDEGDEGEDEGDEGEDEGDEGEDEGDEGEDEGDEGEDEGDE 649
Query: 231 IEE--DKKDDNGFEDDKLSEETELSKEERESVEAKKPELDAMDE-----ESILEGKDEG- 282
E+ D+ +D G E D+ +E + ++E + E + E D DE E EG+DEG
Sbjct: 650 GEDEGDEGEDEGDEGDEGEDEGDEGEDEGDEGEDEGDEGDEGDEGDEGDEGEDEGEDEGE 709
Query: 283 SEKEKSQKDREDDKDKV 299
E ++ KD+E + +KV
Sbjct: 710 DEGDEGTKDKEGNANKV 726
Score = 100 bits (249), Expect = 2e-20
Identities = 99/371 (26%), Positives = 187/371 (49%), Gaps = 24/371 (6%)
Query: 49 EVLEMDKLADDGDVVTENAIKAGDGEGIKEDEKVNEGKEIKEDKQADEGEELKEDKKDNG 108
+VL +DK A++ + + K+ D + +DE E +E D++ DE ED++D
Sbjct: 374 QVLTVDKQANEKEY-KKIIDKSDDRDDRDKDEYELENEEYNRDEEEDE----GEDEEDEK 428
Query: 109 GEERKEDKKVDVGQEVKEDKKVNEGGDIKEEKKADEGEKLKEDKKDDAAVKIKEDKKVNE 168
E+ + + + D G++ ED+ +EG E + DEGE ED+ D+ E + +E
Sbjct: 429 DEKEEGEDEGDDGEDEGEDEGEDEG---DEGDEGDEGEDEGEDEDDEEDEGEDEGDEGDE 485
Query: 169 GEELKE-----EKKADEGEKLKE--DKKDDAGVEIIEDKKVNEGEELEEEKKAEGEELKE 221
GE+ + E + DEG++ K+ D+ D+ E E + +EG+E E+E + EG+E ++
Sbjct: 486 GEDEGDEGDEGEDEGDEGDEGKDEGDEGDEGKDEGDEGDEGDEGDEGEDEWEDEGDEGED 545
Query: 222 --DKKVDAGDEIEEDKKDDNGFEDDKLSEETELSKEERESVEAKKPELDAMDE--ESILE 277
D+ D GDE E++ +D+ +D+ +E + ++E E E + E + DE E E
Sbjct: 546 EGDEGEDEGDEGEDEGEDEGDEGEDEGEDEGDEGEDEGED-EGDEGEDEGEDEGDEGEDE 604
Query: 278 GKDEGSEKEKSQ---KDREDDKDKVDNKSNEENIKVEKRLKKRGKGKVNGENVKKKMKEL 334
G+DEG E ++ + + ED+ D+ +++ +E + ++ + +G+ G+ + + E
Sbjct: 605 GEDEGDEGDEGEDEGDEGEDEGDEGEDEGDEGEDEGDEGEDEGDEGEDEGDEGEDEGDEG 664
Query: 335 KKIEDI-PEAKDESIEKERSRDEEVGDKEKVGGENVKKKMKELKEAEPTTPTTNRPVRER 393
+ ED E +DE E E DE E G+ + + ++ E E T ++
Sbjct: 665 DEGEDEGDEGEDEGDEGEDEGDEGDEGDEGDEGDEGEDEGEDEGEDEGDEGTKDKEGNAN 724
Query: 394 KSVERLVESYD 404
K V+ + Y+
Sbjct: 725 KVVQNPFDYYN 735
Score = 79.7 bits (195), Expect = 3e-14
Identities = 81/277 (29%), Positives = 139/277 (49%), Gaps = 30/277 (10%)
Query: 7 DDSSEKKDLEPKGGKIFEDNAVQDLKEDGIKAMEVDKKADGEEVLEMDKLADDGDVVTEN 66
D+ E KD +G + E + +D ED E D+ +GE+ E D+ D+G+ +
Sbjct: 511 DEGDEGKDEGDEGDEGDEGDEGEDEWEDEGDEGE-DEGDEGED--EGDEGEDEGEDEGDE 567
Query: 67 AIKAGDGEGIKEDEKVNEGKEIKEDKQADEGEELKEDKKDNGGEERKE-DKKVDVGQEVK 125
G+ EG DE +EG++ + D+ DEGE+ ++ +D G +E E D+ D G E +
Sbjct: 568 GEDEGEDEG---DEGEDEGED-EGDEGEDEGEDEGDEGEDEGEDEGDEGDEGEDEGDEGE 623
Query: 126 EDKKVNEGGDIKEEKKADEGEKLKEDKKDDAAVKIKEDKKVNEGEELKE-EKKADEGEKL 184
++ E + E + DEGE ++ +D+ D+ +EG+E E E + DEGE
Sbjct: 624 DEGDEGEDEGDEGEDEGDEGEDEGDEGEDEG------DEGEDEGDEGDEGEDEGDEGED- 676
Query: 185 KEDKKDDAGVEIIEDKKVNEGEELEEEKKAEGEELKEDKKVDAGDEIEEDKKDD------ 238
+ D+ +D G E E + +EG+E E+E + EGE D GDE +DK+ +
Sbjct: 677 EGDEGEDEGDEGDEGDEGDEGDEGEDEGEDEGE--------DEGDEGTKDKEGNANKVVQ 728
Query: 239 NGFEDDKLSEETELSKEERESVEAKKPELDAMDEESI 275
N F+ +++ LS +S+ A + L+ + S+
Sbjct: 729 NPFDYYNWLQKSTLSIVHNKSIHATEHMLEDQLQHSL 765
Score = 74.3 bits (181), Expect = 1e-12
Identities = 86/305 (28%), Positives = 148/305 (48%), Gaps = 47/305 (15%)
Query: 79 DEKVNEGKEIKEDKQADEGEE-LKEDKKDNGG-------EERKEDKKVDVGQEVKEDKKV 130
D K++ E ED DE E + +D+ D+ +E + V + Q + DK+
Sbjct: 324 DHKLSPVSEY-EDFDEDEVELCISDDEVDSEDGNLCVLDDESESVNSVALRQVLTVDKQA 382
Query: 131 NEGGDIKEEKKADEGEKLKEDKKDDAAVKIKEDKKVNEGEELKEEKKADEGEKLKEDKKD 190
NE KE KK + K D +DD +D+ E EE +++ DEGE +ED+KD
Sbjct: 383 NE----KEYKKIID----KSDDRDDR----DKDEYELENEEYNRDEEEDEGED-EEDEKD 429
Query: 191 DAGVEIIEDKKVNEGEELEEEKKAEGEELKEDKKVDAGDEIE-----EDKKDDNGFEDDK 245
+ +++ +EG++ E+E + EGE+ E + D GDE E ED ++D G ++
Sbjct: 430 E------KEEGEDEGDDGEDEGEDEGED--EGDEGDEGDEGEDEGEDEDDEEDEGEDEGD 481
Query: 246 LSEETELSKEERESVEAKKPELDAMDEESILEGKDEGSEKE--KSQKDREDDKDKVDNKS 303
+E E +E + E + E D EGKDEG E + K + D D+ D+ D
Sbjct: 482 EGDEGEDEGDEGDEGEDEGDEGD--------EGKDEGDEGDEGKDEGDEGDEGDEGDEGE 533
Query: 304 NEENIKVEKRLKKRGKGKVNGENVKKKMKELKKIEDIPEAKDESIEKERSRDEEVGDKEK 363
+E + ++ + +G+ G+ + + ++ + E E +DE E E ++E GD+ +
Sbjct: 534 DEWEDEGDEGEDEGDEGEDEGDEGEDEGED-EGDEGEDEGEDEGDEGEDEGEDE-GDEGE 591
Query: 364 VGGEN 368
GE+
Sbjct: 592 DEGED 596
Score = 50.8 bits (120), Expect = 1e-05
Identities = 46/159 (28%), Positives = 79/159 (48%), Gaps = 5/159 (3%)
Query: 3 GNHLDDSSEKKDLEPKGGKIFEDNAVQDLKEDGIKAMEVDKKADGEEVLEMDKLADDGDV 62
G+ +D E + E + E + +D ED E + + +G+E E + D+G+
Sbjct: 565 GDEGEDEGEDEGDEGEDEGEDEGDEGEDEGEDEGDEGEDEGEDEGDEGDEGEDEGDEGED 624
Query: 63 VTENAIKAGDGEGIKEDEKVNEGKEIKE--DKQADEGEE--LKEDKKDNGGEERKE-DKK 117
+ GD + DE +EG E ++ D+ DEG+E ED+ D G +E E + +
Sbjct: 625 EGDEGEDEGDEGEDEGDEGEDEGDEGEDEGDEGEDEGDEGDEGEDEGDEGEDEGDEGEDE 684
Query: 118 VDVGQEVKEDKKVNEGGDIKEEKKADEGEKLKEDKKDDA 156
D G E E + +EG D E++ DEG++ +DK+ +A
Sbjct: 685 GDEGDEGDEGDEGDEGEDEGEDEGEDEGDEGTKDKEGNA 723
Score = 47.8 bits (112), Expect = 1e-04
Identities = 59/230 (25%), Positives = 105/230 (45%), Gaps = 30/230 (13%)
Query: 166 VNEGEELKEEKKADEGEKLKEDKK---DDAGVEIIEDKKVNEG-----EELEEEKKAEGE 217
V+E E+ E DE E D + +D + +++D+ + + L +K+A +
Sbjct: 330 VSEYEDFDE----DEVELCISDDEVDSEDGNLCVLDDESESVNSVALRQVLTVDKQANEK 385
Query: 218 ELKE--DKKVDAGD----EIEEDKKDDNGFEDDKLSEETELSKEERESVEAKKPELDAMD 271
E K+ DK D D E E + ++ N E++ E+ E K+E+E E E D +
Sbjct: 386 EYKKIIDKSDDRDDRDKDEYELENEEYNRDEEEDEGEDEEDEKDEKEEGE---DEGDDGE 442
Query: 272 EESILEGKDEGSEKEKSQKDREDDKDKVDNKSNEENIKVEKRLKKRGKGKVNGENVKKKM 331
+E EG+DEG E ++ + ++ +D+ D + E+ E +G+ G+ +
Sbjct: 443 DEGEDEGEDEGDEGDEGDEGEDEGEDEDDEEDEGEDEGDE-----GDEGEDEGDEGDEGE 497
Query: 332 KELKKIEDIPEAKDESIEKERSRDE-EVGDKEKVGGENVKKKMKELKEAE 380
E ++ E KDE E + +DE + GD+ G E + E E E
Sbjct: 498 DE---GDEGDEGKDEGDEGDEGKDEGDEGDEGDEGDEGEDEWEDEGDEGE 544
>CYL2_BOVIN (Q28092) Cylicin II (Multiple-band polypeptide II)
Length = 488
Score = 113 bits (283), Expect = 2e-24
Identities = 110/396 (27%), Positives = 184/396 (45%), Gaps = 41/396 (10%)
Query: 7 DDSSEKKDLEPKGGKIFEDNAVQDLKEDGIKAMEVDKKADG------EEVLEMDKLADDG 60
D K PK K ED D + + I + E +K +E ++ K D
Sbjct: 109 DAKQAAKPSSPKVKKSKEDKDKSDSEAESIVSKEKPRKLSKAKEEKPDEKKDLKKERKDS 168
Query: 61 DVVTENAI-----KAGDGEGIKEDEKVNE-GKEIKEDKQADEGE---ELKEDKKDNGGEE 111
E+A KAG +G K+D K ++ GKE D +++G+ + K+ KKD+ G+E
Sbjct: 169 KKGKESATESEDEKAGAEKGAKKDRKGSKKGKETPSDSGSEKGDAKKDSKKSKKDSKGKE 228
Query: 112 RKEDKKVDVGQEVKEDKKVNEGGDI-KEEKKADEGEKLKEDKKDDAAVKIKEDKKVNEGE 170
+ + + G K+DKK +G KE EGEK + KKDD K K +G+
Sbjct: 229 SATESEGEKGDAKKDDKKGKKGSKKGKESATESEGEK-GDAKKDDK----KGKKGSKKGK 283
Query: 171 ELKEEKKADEGEKLKEDKK----DDAGVEIIEDKKVNEGEELEEEKKA-----EGEELKE 221
E E + ++G+ K+DKK G E + + +G+ +++KK +G+E
Sbjct: 284 ESATESEGEKGDAKKDDKKGKKGSKKGKESATESEGEKGDAKKDDKKGKKGSKKGKESAT 343
Query: 222 DKKVDAGDEIEEDKKDDNGFEDDKLSEETELSKEERESVEAKKPELDAMDEESILEGKDE 281
+ + + GD ++DKK G + K S+ SK E + +AKK D D++ +GK+
Sbjct: 344 ESEGEKGDAKKDDKKGKKGSKKGKESD----SKAEGDKGDAKKD--DKKDKKGSKKGKES 397
Query: 282 GSEKEKSQKDREDDKDKVDNKSNEENIKVEKRLKKRGKGKVNGENVKKKMKELKKIEDIP 341
+E E +KD + DK + + E + KK K K + KK+ K+ KK +
Sbjct: 398 ATESEGEKKDSKKDKAGKKDPTKAGEKGDESKDKKDAKKK----DSKKEKKDEKKPGEAE 453
Query: 342 EAKDESIEKERSRDEEVGDKEKVGGENVKKKMKELK 377
+S +K+ +D + D +K ++ KK K+ K
Sbjct: 454 SEPKDSAKKDAKKDAK-KDAKKDAKKDAKKDAKKGK 488
Score = 99.8 bits (247), Expect = 3e-20
Identities = 88/323 (27%), Positives = 156/323 (48%), Gaps = 37/323 (11%)
Query: 77 KEDEKVNEGKEIKEDKQADEGEELKEDKKDNGGEERKEDKKVDVGQEVKEDKKVNEGGDI 136
++ K+++ KE K D++ D +E K+ KK ED+K + K+D+K ++ G
Sbjct: 142 EKPRKLSKAKEEKPDEKKDLKKERKDSKKGKESATESEDEKAGAEKGAKKDRKGSKKG-- 199
Query: 137 KEEKKADEGEKLKEDKKDDAAVKIKEDKKVNEGEELKEEKKADEGEKLKEDKK----DDA 192
+E +D G + + KKD K+ KK ++G+E E + ++G+ K+DKK
Sbjct: 200 -KETPSDSGSEKGDAKKDS-----KKSKKDSKGKESATESEGEKGDAKKDDKKGKKGSKK 253
Query: 193 GVEIIEDKKVNEGEELEEEKKAE-----GEELKEDKKVDAGDEIEEDKKDDNGFEDDKLS 247
G E + + +G+ +++KK + G+E + + + GD ++DKK G + K S
Sbjct: 254 GKESATESEGEKGDAKKDDKKGKKGSKKGKESATESEGEKGDAKKDDKKGKKGSKKGKES 313
Query: 248 EETELSKEERESVEAKKPELDAMDEESILEGKDEGSEKEKSQKD-REDDK--DKVDNKSN 304
++ E E +AKK D ++ +GK+ +E E + D ++DDK K K
Sbjct: 314 A----TESEGEKGDAKKD--DKKGKKGSKKGKESATESEGEKGDAKKDDKKGKKGSKKGK 367
Query: 305 EENIKVE-------KRLKKRGKGKVNGENVKKKMKELKKIEDIPEAKDESIEKERSRDEE 357
E + K E K KK KG G+ + + KK KD++ +K+ ++ E
Sbjct: 368 ESDSKAEGDKGDAKKDDKKDKKGSKKGKESATESEGEKK----DSKKDKAGKKDPTKAGE 423
Query: 358 VGDKEKVGGENVKKKMKELKEAE 380
GD+ K + KK K+ K+ E
Sbjct: 424 KGDESKDKKDAKKKDSKKEKKDE 446
Score = 89.4 bits (220), Expect = 3e-17
Identities = 81/350 (23%), Positives = 161/350 (45%), Gaps = 31/350 (8%)
Query: 81 KVNEGKEIKE--DKQADEGEELKEDKKDNGGEERKEDKKVDVGQEVKEDKKVNEGGDIKE 138
KV + KE K+ D +A+ ++ +K + +E K D+K D+ +E K+ KK E E
Sbjct: 120 KVKKSKEDKDKSDSEAESIVSKEKPRKLSKAKEEKPDEKKDLKKERKDSKKGKESATESE 179
Query: 139 EKKADEGEKLKEDKKDDAAVKIKEDKKVNEGEELKEEKKADEGEKLKE---DKKDDAGVE 195
++KA + K+D+K +G+E + +++G+ K+ KKD G E
Sbjct: 180 DEKAGAEKGAKKDRKGS-----------KKGKETPSDSGSEKGDAKKDSKKSKKDSKGKE 228
Query: 196 IIEDKKVNEGEELEEEKKA-----EGEELKEDKKVDAGDEIEEDKKDDNGFEDDKLSEET 250
+ + +G+ +++KK +G+E + + + GD ++DKK G + K S
Sbjct: 229 SATESEGEKGDAKKDDKKGKKGSKKGKESATESEGEKGDAKKDDKKGKKGSKKGKES--- 285
Query: 251 ELSKEERESVEAKKPELDAMDEESILEGKDEG--SEKEKSQKDREDDKDKVDNKSNEENI 308
++ E E +AKK D ++ +GK+ SE EK ++D K K +K +E+
Sbjct: 286 -ATESEGEKGDAKKD--DKKGKKGSKKGKESATESEGEKGDAKKDDKKGKKGSKKGKESA 342
Query: 309 KVEKRLKKRGKGKVNGENVKKKMKELKKIEDIPEAKDESIEKERSRDEEVGDKEKVGGEN 368
+ ++G K + + KK K+ K+ + E +K+ +D++ K K
Sbjct: 343 TESE--GEKGDAKKDDKKGKKGSKKGKESDSKAEGDKGDAKKDDKKDKKGSKKGKESATE 400
Query: 369 VKKKMKELKEAEPTTPTTNRPVRERKSVERLVESYDRDASKEFQIEEGRG 418
+ + K+ K+ + + + + ++ +D+ KE + E+ G
Sbjct: 401 SEGEKKDSKKDKAGKKDPTKAGEKGDESKDKKDAKKKDSKKEKKDEKKPG 450
Score = 72.4 bits (176), Expect = 4e-12
Identities = 84/335 (25%), Positives = 154/335 (45%), Gaps = 32/335 (9%)
Query: 98 EELKEDKKDNGGEERK----EDKKVDVGQEVKEDKKVNEGGDIKEEKKADEGEKLKEDKK 153
E+ K+ K + + +K +DK + + +K + KEEK DE + LK+++K
Sbjct: 108 EDAKQAAKPSSPKVKKSKEDKDKSDSEAESIVSKEKPRKLSKAKEEKP-DEKKDLKKERK 166
Query: 154 DDAAVKIKEDKKVNEGEELKEEK---KADEGEKLKEDKKDDAGVEIIEDKKVNEGEELEE 210
D K KE +E E+ EK K +G K ++ D+G E + KK + +
Sbjct: 167 DSK--KGKESATESEDEKAGAEKGAKKDRKGSKKGKETPSDSGSEKGDAKK----DSKKS 220
Query: 211 EKKAEGEELKEDKKVDAGDEIEEDKKDDNGFEDDKLSEETELSKEERESVEAKKPELDAM 270
+K ++G+E + + + GD ++DKK G + K S ++ E E +AKK D
Sbjct: 221 KKDSKGKESATESEGEKGDAKKDDKKGKKGSKKGKES----ATESEGEKGDAKKD--DKK 274
Query: 271 DEESILEGKDEG--SEKEKSQKDREDDKDKVDNKSNEENIKVEKRLKKRGKGKVNGENVK 328
++ +GK+ SE EK ++D K K +K +E+ + ++G K + + K
Sbjct: 275 GKKGSKKGKESATESEGEKGDAKKDDKKGKKGSKKGKESATESE--GEKGDAKKDDKKGK 332
Query: 329 KKMKELKKIEDIPEAKDESIEKERSRDEEVGDK-EKVGGENVKKKMKELKEAEPTTPTTN 387
K K+ K E E++ E + + +D++ G K K G E+ K + +A+
Sbjct: 333 KGSKKGK--ESATESEGE--KGDAKKDDKKGKKGSKKGKESDSKAEGDKGDAKKDDKKDK 388
Query: 388 RPVRERKSVERLVESYDRDASKEFQIEEGRGTPLK 422
+ ++ K E +D+ K+ + G+ P K
Sbjct: 389 KGSKKGKESATESEGEKKDSKKD---KAGKKDPTK 420
Score = 69.3 bits (168), Expect = 4e-11
Identities = 67/289 (23%), Positives = 133/289 (45%), Gaps = 15/289 (5%)
Query: 125 KEDKKVNEGGDIKEEKKADEGEKLKEDKKDDAAVKIKEDKKVNEGEELKEEKKADEGEKL 184
+ED K + KK+ E +K K D + ++ V ++ +K+++ +E K ++K D ++
Sbjct: 107 QEDAKQAAKPSSPKVKKSKE-DKDKSDSEAESIVSKEKPRKLSKAKEEKPDEKKDLKKER 165
Query: 185 KEDKKDDAGVEIIEDKKVNEGEELEEEKKA--EGEELKEDKKVDAGDEIEEDKKDDNGFE 242
K+ KK ED+K + ++++K +G+E D + GD ++ KK +
Sbjct: 166 KDSKKGKESATESEDEKAGAEKGAKKDRKGSKKGKETPSDSGSEKGDAKKDSKKSKKDSK 225
Query: 243 DDKLSEETELSKEERESVEAKKPELDAMDEESILEGKDEGSEKEKSQKDREDDKDKVDNK 302
+ + E+E K + + + K + +ES E SE EK ++D K K +K
Sbjct: 226 GKESATESEGEKGDAKKDDKKGKKGSKKGKESATE-----SEGEKGDAKKDDKKGKKGSK 280
Query: 303 SNEENIKVEKRLKKRGKGKVNGENVKKKMKELKKIEDIPEAKDESIEKERSRDEEVGDK- 361
+E+ + ++G K + + KK K+ K E E++ E + + +D++ G K
Sbjct: 281 KGKESATESE--GEKGDAKKDDKKGKKGSKKGK--ESATESEGE--KGDAKKDDKKGKKG 334
Query: 362 EKVGGENVKKKMKELKEAEPTTPTTNRPVRERKSVERLVESYDRDASKE 410
K G E+ + E +A+ + ++ K + E DA K+
Sbjct: 335 SKKGKESATESEGEKGDAKKDDKKGKKGSKKGKESDSKAEGDKGDAKKD 383
Score = 64.7 bits (156), Expect = 9e-10
Identities = 110/485 (22%), Positives = 192/485 (38%), Gaps = 68/485 (14%)
Query: 144 EGEKLKEDKKDD-----AAVKIKEDKKVNEGEELKEEKKADEGEKLKEDKKDDAGVEIIE 198
+ EKL+ D+K + ++I E V + +K E +ED K A
Sbjct: 63 DAEKLRGDRKQPLWMHRSLMRISERPSVYLAARSRHPQK--ETPPSQEDAKQAAKPS--- 117
Query: 199 DKKVNEGEELEEEKKAEGEELKEDKKVDAGDEIEEDKKDDNGFEDDKLSEETELSKEERE 258
KV + +E +++ +E E + +K + +E+K D E+ +L KE ++
Sbjct: 118 SPKVKKSKEDKDKSDSEAESIVSKEKPRKLSKAKEEKPD----------EKKDLKKERKD 167
Query: 259 SVEAKKPELDAMDEESILEGKDEGSEKEK--SQKDREDDKDKVDNKSNEENIKVEKRLKK 316
S + K+ ++ DE++ G ++G++K++ S+K +E D K + + K K+ KK
Sbjct: 168 SKKGKESATESEDEKA---GAEKGAKKDRKGSKKGKETPSDSGSEKGDAK--KDSKKSKK 222
Query: 317 RGKGKVNGENVKKKMKELKKIEDIPEAKDESIEKERSRDEEVGDKEKVGGENVKKKMKEL 376
KGK + + + + KK D + K S + + S E G+K ++ K K
Sbjct: 223 DSKGKESATESEGEKGDAKK--DDKKGKKGSKKGKESATESEGEKGDAKKDDKKGKKGSK 280
Query: 377 KEAEPTTPTTNRPVRERKSVERLVESYDRDASKEFQIEEGRGTPLKNIPNVAFKLSRRKV 436
K E T + +K ++ + + + E +G K
Sbjct: 281 KGKESATESEGEKGDAKKDDKKGKKGSKKGKESATESEGEKGDAKK-------------- 326
Query: 437 DDTLKFLHTILFCRRGKAAVIKKNILRFSGFVWHENEEKQMIKVKEKFDKCNKEKLLEFS 496
DD ++GK K + EK K +K K +K E
Sbjct: 327 DD-----------KKGK-----KGSKKGKESATESEGEKGDAKKDDKKGKKGSKKGKESD 370
Query: 497 DLLDVPVGNANTRKEDIIAKLIDFLVAPQVTKSVLLAEQEKSAKEKRIAKQGSTGSGTPT 556
+ G+A +K+D K T+S ++K +K+ + K+ T +G
Sbjct: 371 SKAEGDKGDA--KKDDKKDKKGSKKGKESATES---EGEKKDSKKDKAGKKDPTKAGEKG 425
Query: 557 SRRSAKSRKKIEDSSIAEKKKTATDTESESE-KDEENKEENEIDVSDKSEDEKPIKGKKH 615
K K +DS EKK E+ESE KD K+ + D +D K K K
Sbjct: 426 DESKDKKDAKKKDSK-KEKKDEKKPGEAESEPKDSAKKDAKKDAKKDAKKDAK--KDAKK 482
Query: 616 IAKQG 620
AK+G
Sbjct: 483 DAKKG 487
Score = 58.5 bits (140), Expect = 7e-08
Identities = 57/227 (25%), Positives = 103/227 (45%), Gaps = 27/227 (11%)
Query: 161 KEDKKVNEGEELKEEKKADEGEKLKEDK-KDDAGVE-IIEDKKVNEGEELEEEKKAEGEE 218
KE E + + + + +K KEDK K D+ E I+ +K + + +EEK E ++
Sbjct: 101 KETPPSQEDAKQAAKPSSPKVKKSKEDKDKSDSEAESIVSKEKPRKLSKAKEEKPDEKKD 160
Query: 219 LKEDKKVDAGDEIEEDKKDDNGFEDDKLSEETELSKEERESVEAKKPELDAMDEESILEG 278
LK+++K + ++ K+ ED+K E K+ + S + K+ D+ G
Sbjct: 161 LKKERK-----DSKKGKESATESEDEKAGAEKGAKKDRKGSKKGKETPSDS--------G 207
Query: 279 KDEGSEKEKSQKDREDDKDKVDNKSNE-------ENIKVEKRLKKRGKGKV---NGENVK 328
++G K+ S+K ++D K K +E ++ K K+ K+GK GE
Sbjct: 208 SEKGDAKKDSKKSKKDSKGKESATESEGEKGDAKKDDKKGKKGSKKGKESATESEGEKGD 267
Query: 329 KKMKELKKIEDIPEAKDESIEKERSRDEEVGDKEKVGGENVKKKMKE 375
K + K + + K+ + E E + + D +K G+ KK KE
Sbjct: 268 AKKDDKKGKKGSKKGKESATESEGEKGDAKKDDKK--GKKGSKKGKE 312
Score = 47.8 bits (112), Expect = 1e-04
Identities = 78/381 (20%), Positives = 151/381 (39%), Gaps = 65/381 (17%)
Query: 277 EGKDEGSEKEKSQKDREDDKDKVDNKSNEENIKVEKRLKKRGKGKVNGENVKKKMKELKK 336
+ K K ++DKDK D+++ E+I +++ +K K K + KK +K+ +K
Sbjct: 109 DAKQAAKPSSPKVKKSKEDKDKSDSEA--ESIVSKEKPRKLSKAKEEKPDEKKDLKKERK 166
Query: 337 IEDIPEAKDESIEKERSRDEEVGDKEKVGGENVKKKMKELKEAEPTTPTTNRPVRERKSV 396
D + K+ + E E DE+ G ++ G + +K K+ KE P+ + + ++ S
Sbjct: 167 --DSKKGKESATESE---DEKAGAEK--GAKKDRKGSKKGKET-PSDSGSEKGDAKKDSK 218
Query: 397 ERLVESYDRDASKEFQIEEGRGTPLKNIPNVAFKLSRRKVDDTLKFLHTILFCRRGKAAV 456
+ +S ++++ E + E+G K DD ++GK
Sbjct: 219 KSKKDSKGKESATESEGEKGDA----------------KKDD-----------KKGKKGS 251
Query: 457 IKKNILRFSGFVWHENEEKQMIKVKEKFDKCNKEKLLEFSDLLDVPVGNANTRKEDIIAK 516
KK + + + K+ K +K K KE E + +K+D K
Sbjct: 252 -KKGKESATESEGEKGDAKKDDKKGKKGSKKGKESATESEG------EKGDAKKDDKKGK 304
Query: 517 LIDFLVAPQVTKSVLLAEQEKSAKEKRIAKQGSTGSGTPTSRRSAKSRKKIEDS---SIA 573
+ K KE +G G ++ K KK ++S S
Sbjct: 305 -----------------KGSKKGKESATESEGEKGDAKKDDKKGKKGSKKGKESATESEG 347
Query: 574 EKKKTATDTESESEKDEENKEENEIDVSDKSEDEKPIKGKKHIAKQG-SSRSGTASSRRS 632
EK D + + ++ KE + DK + +K K K +K+G S + + ++
Sbjct: 348 EKGDAKKDDKKGKKGSKKGKESDSKAEGDKGDAKKDDKKDKKGSKKGKESATESEGEKKD 407
Query: 633 AKE*NIFQKERIRCTKQSKES 653
+K+ +K+ + ++ ES
Sbjct: 408 SKKDKAGKKDPTKAGEKGDES 428
Score = 38.9 bits (89), Expect = 0.054
Identities = 32/124 (25%), Positives = 56/124 (44%), Gaps = 11/124 (8%)
Query: 537 KSAKEKRIAKQGSTGSGTPTSRRSAKSRKKIEDSSI------AEKKKTATDTESESEKDE 590
K KE +G G ++ K KK ++S+ + KK + S+K +
Sbjct: 252 KKGKESATESEGEKGDAKKDDKKGKKGSKKGKESATESEGEKGDAKKDDKKGKKGSKKGK 311
Query: 591 ENKEENEIDVSDKSEDEKPIKGKKHIAKQGSSRSGTASSRRSAKE*NIFQKERIRCTKQS 650
E+ E+E + D +D+K KGKK K S + + + AK+ K+ + +K+
Sbjct: 312 ESATESEGEKGDAKKDDK--KGKKGSKKGKESATESEGEKGDAKK---DDKKGKKGSKKG 366
Query: 651 KESN 654
KES+
Sbjct: 367 KESD 370
Score = 38.1 bits (87), Expect = 0.092
Identities = 50/200 (25%), Positives = 83/200 (41%), Gaps = 33/200 (16%)
Query: 473 EEKQMIKVKEKFDKCNKEKLLEFSD-LLDVPVGNANTRKEDIIAKLIDFLVAPQVTKSVL 531
+EK+ +K + K K KE E D G RK K T S
Sbjct: 156 DEKKDLKKERKDSKKGKESATESEDEKAGAEKGAKKDRKGSKKGK---------ETPSDS 206
Query: 532 LAEQEKSAKEKRIAKQGSTGSGTPTSRRSAKSRKKIEDSS----IAEKKKTATDTESE-- 585
+E+ + K+ + +K+ S G + T K K +D + K++AT++E E
Sbjct: 207 GSEKGDAKKDSKKSKKDSKGKESATESEGEKGDAKKDDKKGKKGSKKGKESATESEGEKG 266
Query: 586 ------------SEKDEENKEENEIDVSDKSEDEKPIKGKKHIAKQGSSRSGTASSRRSA 633
S+K +E+ E+E + D +D+K KGKK K S + + + A
Sbjct: 267 DAKKDDKKGKKGSKKGKESATESEGEKGDAKKDDK--KGKKGSKKGKESATESEGEKGDA 324
Query: 634 KE*NIFQKERIRCTKQSKES 653
K+ K+ + +K+ KES
Sbjct: 325 KK---DDKKGKKGSKKGKES 341
Score = 36.6 bits (83), Expect = 0.27
Identities = 35/131 (26%), Positives = 55/131 (41%), Gaps = 27/131 (20%)
Query: 537 KSAKEKRIAKQGSTGSGTPTSRRSAKSRKKIEDSSIAEKKKTATDTESE----------- 585
K KE +G G ++ K KK K++AT++E E
Sbjct: 280 KKGKESATESEGEKGDAKKDDKKGKKGSKK--------GKESATESEGEKGDAKKDDKKG 331
Query: 586 ---SEKDEENKEENEIDVSDKSEDEKPIKGKKHIAKQGSSRSGTASSRRSAKE*NIFQKE 642
S+K +E+ E+E + D +D+K KGKK K S S + AK+ K+
Sbjct: 332 KKGSKKGKESATESEGEKGDAKKDDK--KGKKGSKKGKESDSKAEGDKGDAKK---DDKK 386
Query: 643 RIRCTKQSKES 653
+ +K+ KES
Sbjct: 387 DKKGSKKGKES 397
Score = 33.5 bits (75), Expect = 2.3
Identities = 27/102 (26%), Positives = 50/102 (48%), Gaps = 4/102 (3%)
Query: 554 TPTSRRSAKSRKKIEDSSIAEKK--KTATDTESESEKDEENKEENEIDVSDKSEDEKPIK 611
TP S+ AK K + + K K +D+E+ES +E + +K +++K +K
Sbjct: 103 TPPSQEDAKQAAKPSSPKVKKSKEDKDKSDSEAESIVSKEKPRKLSKAKEEKPDEKKDLK 162
Query: 612 GKKHIAKQGSSRSGTASSRRSAKE*NIFQKERIRCTKQSKES 653
++ +K+G S T S A +K+R + +K+ KE+
Sbjct: 163 KERKDSKKG-KESATESEDEKAGAEKGAKKDR-KGSKKGKET 202
>DEK_HUMAN (P35659) DEK protein
Length = 375
Score = 110 bits (275), Expect = 1e-23
Identities = 107/444 (24%), Positives = 193/444 (43%), Gaps = 92/444 (20%)
Query: 335 KKIEDIPEAKDESIEKERSRDEEVGDKEKVGGENVKKKMKELKEAEPTTPTTNRPVRERK 394
+K ++P ++ES E+E DEE ++EK V+ K RE+K
Sbjct: 20 EKEPEMPGPREESEEEEDEDDEEEEEEEKEKSLIVEGK------------------REKK 61
Query: 395 SVERLVESYDRDASKEFQIEEGRGTPLKNIPNVAFKLSRRKVDDTLKFLHTILFCRRGKA 454
VERL + F I +G+G L I + F LS++K D+ L+ LH +L+ R G
Sbjct: 62 KVERLTMQVSSLQREPFTIAQGKGQKLCEIERIHFFLSKKKTDE-LRNLHKLLYNRPGTV 120
Query: 455 AVIKKNILRFSGFVWHENEEKQMIKVKEKFDKCNKEKLLEFSDLLDVPVGNANTRKEDII 514
+ +KKN+ +FSGF + E Q K +E K L ++LD+ N+ +++
Sbjct: 121 SSLKKNVGQFSGFPF-EKGSVQYKKKEEMLKKFRNAMLKSICEVLDLERSGVNS---ELV 176
Query: 515 AKLIDFLVAPQVTKSVLLAEQEKSAKEKRIAKQGSTGSGTPTSRRSAKSRKKIEDSSIAE 574
++++FL+ P+ + L K K+ +GS R S+ +K + + E
Sbjct: 177 KRILNFLMHPKPSGKPL-------PKSKKTCSKGS-----KKERNSSGMARKAKRTKCPE 224
Query: 575 KKKTATDTESESEKDEENKEENEIDVSDKSEDEKPIKGKKHIAKQGSSRSGTASSRRSAK 634
+D S E +++NKEE+ D +SE+E P KK ++ + T+ S++S K
Sbjct: 225 ---ILSDESSSDEDEKKNKEESSDDEDKESEEEPP---KKTAKREKPKQKATSKSKKSVK 278
Query: 635 E*NIFQKERIRCTKQSKESNR*NKTSLGTKANF*EAIVYTLCI*SW***WKSQGLFKEEE 694
N+ +K TK+++ S++
Sbjct: 279 SANV-KKADSSTTKKNQNSSK--------------------------------------- 298
Query: 695 K*KTRKAEDLNSHQVFLQRQSRKIKNKEKSDPSDDQLRKAICVIFKKVDFNTATFADILK 754
K ++ED + + ++ K K P+D++L++ I + + T I K
Sbjct: 299 --KESESEDSSDDEPLIK--------KLKKPPTDEELKETIKKLLASANLEEVTMKQICK 348
Query: 755 LLGKQFDV-DLTPRKASVKTIIQQ 777
+ + + DLT RK +KT +++
Sbjct: 349 KVYENYPTYDLTERKDFIKTTVKE 372
Score = 48.9 bits (115), Expect = 5e-05
Identities = 86/383 (22%), Positives = 151/383 (38%), Gaps = 65/383 (16%)
Query: 70 AGDGEGI-------KEDEKVNEGKEIKEDKQADEGEELKEDKKDNGGEERKEDKK----- 117
A +GEG KE E +E +E++ D+ EE +E+K+ + E K +KK
Sbjct: 7 AAEGEGTPTQPASEKEPEMPGPREESEEEEDEDDEEEEEEEKEKSLIVEGKREKKKVERL 66
Query: 118 -VDVGQEVKEDKKVNEGGDIK-----------EEKKADEGEKLKEDKKDDAAVKIKEDKK 165
+ V +E + +G K +KK DE L + + K
Sbjct: 67 TMQVSSLQREPFTIAQGKGQKLCEIERIHFFLSKKKTDELRNLHKLLYNRPGTVSSLKKN 126
Query: 166 VNEGEELKEEKKADEGEKLKEDKKDDAGV------EIIEDKKVNEGEELEEE-------K 212
V + EK + + +K +E K E+++ ++ EL +
Sbjct: 127 VGQFSGFPFEKGSVQYKKKEEMLKKFRNAMLKSICEVLDLERSGVNSELVKRILNFLMHP 186
Query: 213 KAEGEELKEDKKVDAGDEIEEDKKDDNGFEDDKLSEETELSKEERESVEAKKPELDAMDE 272
K G+ L + KK + + KK+ N S R++ K PE+ + +
Sbjct: 187 KPSGKPLPKSKKTCS----KGSKKERNS------------SGMARKAKRTKCPEI--LSD 228
Query: 273 ESILEGKDEGSEKEKSQKDREDDKDKVDN--KSNEENIKVEKRLKKRGKGKVNGENVKKK 330
ES DE +K K + ++DK+ + K + K +++ + K V NVKK
Sbjct: 229 ES---SSDEDEKKNKEESSDDEDKESEEEPPKKTAKREKPKQKATSKSKKSVKSANVKKA 285
Query: 331 MKELKKIEDIPEAKDESIEKERSRDEEVGDKEK--VGGENVKKKMKELKEAEPTTPTTNR 388
K ++ +K ES ++ S DE + K K E +K+ +K+L + T +
Sbjct: 286 DSSTTK-KNQNSSKKESESEDSSDDEPLIKKLKKPPTDEELKETIKKLLASANLEEVTMK 344
Query: 389 PVRERKSVERLVESYDRDASKEF 411
+ K V +YD K+F
Sbjct: 345 QI--CKKVYENYPTYDLTERKDF 365
>CALD_CHICK (P12957) Caldesmon (CDM)
Length = 771
Score = 107 bits (268), Expect = 9e-23
Identities = 146/624 (23%), Positives = 259/624 (41%), Gaps = 82/624 (13%)
Query: 12 KKDLEPKGGKIFEDNAVQDLKEDGIKAMEVD----KKADGEEVLEMDKLADDGDVVTENA 67
++D E +G K +D+ + KE + +VD K D EEV+E LA + + T
Sbjct: 171 RQDGEEEGKKEEKDSEEEKPKEVPTEENQVDVAVEKSTDKEEVVETKTLAVNAENDTNAM 230
Query: 68 IKAGDGEGIKEDEKVNEGKEIKEDKQADEGEELKEDKKDNGGEER---KEDKKVDVGQE- 123
++ D++ E ++ +E +A+E E LK +++ EE+ +E+KK +E
Sbjct: 231 LEGEQSITDAADKEKEEAEKEREKLEAEEKERLKAEEEKKAAEEKQKAEEEKKAAEERER 290
Query: 124 --VKEDKKVNEGGD----IKEEKKADEGEKLKEDKKDDAA---VKIKEDKKVNEGEELKE 174
+E+K+ E + +E K A+E E+ K +++ AA K +E++K E E
Sbjct: 291 AKAEEEKRAAEERERAKAEEERKAAEERERAKAEEERKAAEERAKAEEERKAAEERAKAE 350
Query: 175 EKKADEGEKLKEDKKDDAGVEIIEDKKVNEGEELEEEKKAEGEELKEDKKVDAGDEIEED 234
E++ E+ K +K+ A E K E EE+ + E E+LKE KK +EE
Sbjct: 351 EERKAAEERAKAEKERKAAEERERAKAEEEKRAAEEKARLEAEKLKEKKK------MEEK 404
Query: 235 KKDDNGFEDDKLSEETELSKEERESVEAKKPEL-DAMDEESILEGKDEGSEKEKSQKD-- 291
K + + + L ++ E ++ VEAKK L + + S + + +KEK+ K+
Sbjct: 405 KAQEEKAQANLLRKQEE---DKEAKVEAKKESLPEKLQPTSKKDQVKDNKDKEKAPKEEM 461
Query: 292 -------REDDKDKVDNKSNE---------ENIKVEKRLKKRGKGKVNGENVKKKMK--- 332
R + K N E EN LK + E +K+K +
Sbjct: 462 KSVWDRKRGVPEQKAQNGERELTTPKLKSTENAFGRSNLKGAANAEAGSEKLKEKQQEAA 521
Query: 333 -ELKKIEDIPEAKDESIEKERSRDEEVGDKEKVGGENVKKKMKELKEAEPTTPTTNRPVR 391
EL +++ E + + +E+E + ++ + K+ E KK+MKE E R
Sbjct: 522 VELDELKKRREERRKILEEEEQKKKQEEAERKIREEEEKKRMKEEIE--------RRRAE 573
Query: 392 ERKSVERLVESYDRDASKEFQIEEGRGTPLKNIPNVAFKLSRRKVDDTLKFLHTILFCRR 451
+ +++ E + K F+ +G+ LK I A L++ +K HT
Sbjct: 574 AAEKRQKVPEDGVSEEKKPFKCFSPKGSSLK-IEERAEFLNKSAQKSGMKPAHT------ 626
Query: 452 GKAAVIKKNILRFSGFVWHENEEKQMIKVKEKFDKC--------NKEKLLEFSDLLDVPV 503
AV+ K R + K K N + + E ++ P
Sbjct: 627 --TAVVSKIDSRLEQYTSAVVGNKAAKPAKPAASDLPVPAEGVRNIKSMWEKGNVFSSPG 684
Query: 504 GNANTRKEDIIAKL-IDFLVAPQVTKSVLLAEQEKSAKEKRIAKQGSTGSGTPTSRRSAK 562
G KE K+ + + +TK+ E KS K G + +R+
Sbjct: 685 GTGTPNKETAGLKVGVSSRINEWLTKT---PEGNKSP----APKPSDLRPGDVSGKRNLW 737
Query: 563 SRKKIEDSSIAEKKKTATDTESES 586
++ +E + + K TAT +SE+
Sbjct: 738 EKQSVEKPAASSSKVTATGKKSET 761
Score = 87.8 bits (216), Expect = 1e-16
Identities = 135/599 (22%), Positives = 246/599 (40%), Gaps = 82/599 (13%)
Query: 77 KEDEKVNEGKEIKEDKQADEGEEL-KEDKKDNGGEERKEDKKVDVGQEVKEDKKVNEGGD 135
K +E E + + + D+ EE +E ++ E ++ ++ DV EV E +VN
Sbjct: 14 KREEMRLEAERLSYQRNDDDEEEAARERRRRARQERLRQKEEGDVSGEVTEKSEVNAQNS 73
Query: 136 IKEEKKADEGEKLKEDKKDDAAVKIKEDKKVNEGEELKEEKKADEGEKLKEDKKDDAGVE 195
+ E E+ K D+AA + E E K ++A E +K + D +
Sbjct: 74 VAE-------EETKRSTDDEAA--LLERLARREERRQKRLQEALERQKEFDPTITDGSLS 124
Query: 196 IIEDKKVNEGEELE---EEKKAEGE----ELKEDKKVDAG--------DEIEEDKKDDNG 240
+ ++VN EE E +E+K E E++E + V D EE KK++
Sbjct: 125 VPSRREVNNVEENEITGKEEKVETRQGRCEIEETETVTKSYQRNNWRQDGEEEGKKEEKD 184
Query: 241 FEDDKLSE----------ETELSKEERESVEAKKPELDA-MDEESILEGKD---EGSEKE 286
E++K E E S ++ E VE K ++A D ++LEG+ + ++KE
Sbjct: 185 SEEEKPKEVPTEENQVDVAVEKSTDKEEVVETKTLAVNAENDTNAMLEGEQSITDAADKE 244
Query: 287 KSQKDREDDKDKVDNKSNEENIKVEKRLKKRGKGKVNGENVKKKMKELKKIEDIPEAKDE 346
K + ++E +K + + K E +K E+ KK + K E KK +E ++ + E K
Sbjct: 245 KEEAEKEREKLEAEEK---ERLKAEEE-KKAAEEKQKAEEEKKAAEERERAK-AEEEKRA 299
Query: 347 SIEKERSRDEE----VGDKEKVGGENVKKKMKELKEAEPTTPTTNRPVR---ERKSV-ER 398
+ E+ER++ EE ++E+ E +K +E +AE + ERK+ ER
Sbjct: 300 AEERERAKAEEERKAAEERERAKAEEERKAAEERAKAEEERKAAEERAKAEEERKAAEER 359
Query: 399 LVESYDRDASKEFQIEEGRGTPLKNIPNVAFKLSRRKVDDTLKFLHTILFCRRGKAAVIK 458
+R A++E E + K +L K+ + K + +A +++
Sbjct: 360 AKAEKERKAAEE--RERAKAEEEKRAAEEKARLEAEKLKEKKKMEEKKAQEEKAQANLLR 417
Query: 459 KNILRFSGFVWHENE----------EKQMIKVKEKFDKCNKEKLLEFSD-LLDVPVGNAN 507
K V + E +K +K + +K KE++ D VP A
Sbjct: 418 KQEEDKEAKVEAKKESLPEKLQPTSKKDQVKDNKDKEKAPKEEMKSVWDRKRGVPEQKAQ 477
Query: 508 TRKEDIIAKLIDFLVAPQVTKSVLLAEQEKSAKEKRIAKQGSTGSGTPTSRRSAKSRKKI 567
+ ++ + ++ A ++ EK KQ ++ + R+KI
Sbjct: 478 NGERELTTPKLKSTENAFGRSNLKGAANAEAGSEKLKEKQQEAAVELDELKKRREERRKI 537
Query: 568 EDSSIAEKKKTATDTESESEKDEENK------EENEIDVSDK---------SEDEKPIK 611
+ E+KK + E + ++EE K E + ++K SE++KP K
Sbjct: 538 LEEE--EQKKKQEEAERKIREEEEKKRMKEEIERRRAEAAEKRQKVPEDGVSEEKKPFK 594
Score = 63.5 bits (153), Expect = 2e-09
Identities = 94/463 (20%), Positives = 183/463 (39%), Gaps = 70/463 (15%)
Query: 284 EKEKSQKDREDDKDKVDNKSNEENIKVEKRLKKRGKGKVNGENVKKKMKELKKIEDIPEA 343
E E+ R DD ++ + + E RL+++ +G V+GE +K + E
Sbjct: 21 EAERLSYQRNDDDEEEAARERRRRARQE-RLRQKEEGDVSGEVTEKSEVNAQNSVAEEET 79
Query: 344 KDESIEKERSRDEEVGDKEKVGGENVKKKMKELKEAEPTTPTTNRPVRERKSVERLVESY 403
K S + E + E + +E+ + +++ ++ KE +PT + V R+ V + E+
Sbjct: 80 K-RSTDDEAALLERLARREERRQKRLQEALERQKEFDPTITDGSLSVPSRREVNNVEENE 138
Query: 404 DRDASKEFQIEEGRGTPLKNIPNVAFKLSRRKVDDTLKFLHTILFCRRGKAAVIKKNILR 463
++ + +GR C + + K+ R
Sbjct: 139 ITGKEEKVETRQGR-------------------------------CEIEETETVTKSYQR 167
Query: 464 FSGFVWHENEEKQMIKVKEKFDKCNKEKLLEFSDLLDVPVGNANTRKEDIIAKLIDFLVA 523
+ W ++ E++ K ++ ++ +++ + +DV V +T KE+++ + A
Sbjct: 168 NN---WRQDGEEEGKKEEKDSEEEKPKEVPTEENQVDVAV-EKSTDKEEVVETKTLAVNA 223
Query: 524 PQVTKSVLLAEQ---EKSAKEKRIA-KQGSTGSGTPTSRRSAKSRKKI-EDSSIAEKKKT 578
T ++L EQ + + KEK A K+ R A+ KK E+ AE++K
Sbjct: 224 ENDTNAMLEGEQSITDAADKEKEEAEKEREKLEAEEKERLKAEEEKKAAEEKQKAEEEKK 283
Query: 579 ATDTESESEKDEENKEENEIDVSDKSEDEKPIKGKKHIAKQGSSRSGTASSRRSAKE*NI 638
A + E E K EE K E K+E+E+ ++ AK R A R A+E
Sbjct: 284 AAE-ERERAKAEEEKRAAEERERAKAEEERKAAEERERAKAEEERKA-AEERAKAEEERK 341
Query: 639 FQKERIRCTKQSKESNR*NKTSLGTKANF*EAIVYTLCI*SW***WKSQGLFKEEEK*KT 698
+ER + ++ K + K KA EE+ +
Sbjct: 342 AAEERAKAEEERKAAEERAKAEKERKA--------------------------AEERERA 375
Query: 699 RKAEDLNSHQVFLQRQSRKIKNKEKSDPSDDQLRKAICVIFKK 741
+ E+ + + + ++ K+K K+K + Q KA + +K
Sbjct: 376 KAEEEKRAAEEKARLEAEKLKEKKKMEEKKAQEEKAQANLLRK 418
Score = 53.5 bits (127), Expect = 2e-06
Identities = 88/433 (20%), Positives = 180/433 (41%), Gaps = 55/433 (12%)
Query: 244 DKLSEETELSKEERESVEAKKPEL-----DAMDEESILEGKDEGSEKEKSQKDREDDKDK 298
D EL +++RE + + L D +EE+ E + ++ QK+ D +
Sbjct: 2 DDFERRRELRRQKREEMRLEAERLSYQRNDDDEEEAARERRRRARQERLRQKEEGDVSGE 61
Query: 299 VDNKS--NEENIKVEKRLKKRGKGKVNGENVKKKMKELKKIEDIPEAK-DESIEKERSRD 355
V KS N +N E+ K+ + ++ ++ L + E+ + + E++E+++ D
Sbjct: 62 VTEKSEVNAQNSVAEEETKR------STDDEAALLERLARREERRQKRLQEALERQKEFD 115
Query: 356 EEVGDKEKVGGENV--KKKMKELKEAEPTTPTTNRPVR----ERKSVERLVESYDRDASK 409
+ D G +V ++++ ++E E T R E + E + +SY R+ +
Sbjct: 116 PTITD----GSLSVPSRREVNNVEENEITGKEEKVETRQGRCEIEETETVTKSYQRNNWR 171
Query: 410 EFQIEEGRGTPLKNIPNVAFKLSRRKVDDTLKFLHTILFCRRGKAAVIKKNILRFSGFVW 469
+ EEG K + + ++V + + K V++ L +
Sbjct: 172 QDGEEEG-----KKEEKDSEEEKPKEVPTEENQVDVAVEKSTDKEEVVETKTLAVNA--- 223
Query: 470 HENEEKQMIKVKEKF-DKCNKEKLLEFSDLLDVPVGNANTRKEDIIAKLIDFLVAPQVTK 528
EN+ M++ ++ D +KEK A +E + A+ + L A + K
Sbjct: 224 -ENDTNAMLEGEQSITDAADKEK------------EEAEKEREKLEAEEKERLKAEEEKK 270
Query: 529 SV---LLAEQEKSAKEKRIAKQGSTGSGTPTSRRSAKS---RKKIEDSSIAEKKKTATDT 582
+ AE+EK A E+R + R AK+ RK E+ A+ ++
Sbjct: 271 AAEEKQKAEEEKKAAEERERAKAEEEKRAAEERERAKAEEERKAAEERERAKAEEERKAA 330
Query: 583 ESESEKDEENK---EENEIDVSDKSEDEKPIKGKKHIAKQGSSRSGTASSRRSAKE*NIF 639
E ++ +EE K E + + K+ +E+ K+ A + R+ +R+A+E
Sbjct: 331 EERAKAEEERKAAEERAKAEEERKAAEERAKAEKERKAAEERERAKAEEEKRAAEEKARL 390
Query: 640 QKERIRCTKQSKE 652
+ E+++ K+ +E
Sbjct: 391 EAEKLKEKKKMEE 403
Score = 50.4 bits (119), Expect = 2e-05
Identities = 99/476 (20%), Positives = 190/476 (39%), Gaps = 74/476 (15%)
Query: 171 ELKEEKKAD---EGEKLKEDKKDDAGVEIIEDKKVNEGEELEEEKKAEGEELKEDKKVDA 227
EL+ +K+ + E E+L + DD E +++ ++A E L++ ++ D
Sbjct: 9 ELRRQKREEMRLEAERLSYQRNDDDEEEAARERR----------RRARQERLRQKEEGDV 58
Query: 228 GDEIEEDKKDDNGFEDDKLSEETELSKEERESVEAKKPELDAMDEESILEGKDEGSEKEK 287
E+ E K + ++ EET+ S ++ EA E A EE + E E++K
Sbjct: 59 SGEVTE--KSEVNAQNSVAEEETKRSTDD----EAALLERLARREERRQKRLQEALERQK 112
Query: 288 S-QKDREDDKDKVDNKSNEENIKVEKRLKKRGKGKVNGENVKKKMKELK-KIEDIPEAKD 345
D V ++ N++ + ++ G+ K + ++ + +IE+
Sbjct: 113 EFDPTITDGSLSVPSRREVNNVE---------ENEITGKEEKVETRQGRCEIEET----- 158
Query: 346 ESIEKERSRDEEVGDKEKVGGENVKKKMKELKEAEPTTPTTNRPVRERKSVERLVESYDR 405
E++ K R+ D E+ G KK+ K+ +E +P T E V+ VE +
Sbjct: 159 ETVTKSYQRNNWRQDGEEEG----KKEEKDSEEEKPKEVPT-----EENQVDVAVE---K 206
Query: 406 DASKEFQIE-EGRGTPLKNIPNVAFKLSRRKVDDTLKFLHTILFCRRGKAAVIKKNILRF 464
KE +E + +N N + + D K + +A ++ +
Sbjct: 207 STDKEEVVETKTLAVNAENDTNAMLEGEQSITDAADK--------EKEEAEKEREKL--- 255
Query: 465 SGFVWHENEEKQMIKVKEKFDKCNKEKLLEFSDLLDVPVGNANTRKEDIIAKLIDFLVAP 524
E EEK+ +K +E+ +++ E A +E A+ + A
Sbjct: 256 ------EAEEKERLKAEEEKKAAEEKQKAEEEKKAAEERERAKAEEEKRAAEERERAKAE 309
Query: 525 QVTKSV-----LLAEQEKSAKEKRIAKQGSTGSGTPTSRRSAKSRKKIEDSSIAEKKKTA 579
+ K+ AE+E+ A E+R AK ++ + RK E+ + AEK++ A
Sbjct: 310 EERKAAEERERAKAEEERKAAEER-AKAEEERKAAEERAKAEEERKAAEERAKAEKERKA 368
Query: 580 TDTESESEKDEENKEENEIDVSDKSEDEKPIKGKKHIAKQGSSRSGTASSRRSAKE 635
+ ++ +EE + E + E EK + KK K+ A+ R +E
Sbjct: 369 AEERERAKAEEEKRAAEE---KARLEAEKLKEKKKMEEKKAQEEKAQANLLRKQEE 421
>NSB1_MOUSE (Q9JL35) Nucleosome binding protein 1 (Nucleosome
binding protein 45) (NBP-45) (GARP45 protein)
Length = 406
Score = 103 bits (257), Expect = 2e-21
Identities = 96/317 (30%), Positives = 161/317 (50%), Gaps = 33/317 (10%)
Query: 13 KDLEPKGGKIFEDNAVQDLKEDGIKA--MEVDKKADGEEVLEMDKLADDGDVVTENAIKA 70
+D E GG+ E A + K+D +KA +V+K DG+E + + +DG + E +
Sbjct: 103 EDTEEDGGEKKEAVAAE-AKDDELKANIQDVEKDEDGKEHKDTGEEVEDGKI-EEEGLNE 160
Query: 71 GDGEGIKEDEKVNEGKEIKEDKQADEGEELKEDKKDNGGEERKEDKKVDVG--QEVKEDK 128
G ED +V++ +E K D + +GE+ KE+ + EE K+DK+ D G +EVKE
Sbjct: 161 KPGTAKSEDAEVSKDEEEKGDNE--KGEDGKEEGDEK--EEEKDDKEGDTGTEKEVKEQN 216
Query: 129 KVNE--GGDIKEEKKADEGEK--LKEDKKDDAAVKI-KEDKKVNEGEELKEEKKADE--- 180
K E G KEE+ + G++ +ED K+D ++ KED +G+E + E+ E
Sbjct: 217 KEAEEDDGKCKEEENKEVGKEGQPEEDGKEDLHEEVGKEDLHEEDGKEGQPEEDGKEIHH 276
Query: 181 GEKLKEDKKDDAGVEIIEDKKVNEGEELEEEKKAEGEELKEDKKVDAGDEIEEDKKDDNG 240
E KE + ++ G E + ++ EG+ E++K+ + EE ++ D+ EED K+
Sbjct: 277 EEDGKEGQPEEDGKEYLHEEDGEEGQPKEDQKEGQPEEDGKE------DQPEEDGKEGQC 330
Query: 241 FEDDKLSEETELSKEERESVEAKKPELDAMDEESILEGK-----DEGSEKEKSQKDRE-- 293
ED K E KE+ + K E D E+ EG+ DEGS++ K + + E
Sbjct: 331 KEDGKEGHHEEGGKEDLHEEDGK--EKDGGKEDRKEEGEQEVAVDEGSDENKVEAEEEGA 388
Query: 294 DDKDKVDNKSNEENIKV 310
++KD + EE + +
Sbjct: 389 ENKDFKQDGEKEEPLSI 405
Score = 93.2 bits (230), Expect = 2e-18
Identities = 99/346 (28%), Positives = 164/346 (46%), Gaps = 45/346 (13%)
Query: 16 EPKGGKIFEDNAVQDLKEDGIKAMEVD-KKADGEEVLEM---DKLADDGDVVTENAIKAG 71
E K + ++ +++ + K ME K + EEV E D D G+ A +A
Sbjct: 62 ETKPEDVKDECNMENAENGEAKIMEAPIPKMEAEEVKEQINEDTEEDGGEKKEAVAAEAK 121
Query: 72 DGE---GIKEDEKVNEGKEIKEDKQADEGEELKEDK------KDNGGEERKEDKKVDVGQ 122
D E I++ EK +GKE K D GEE+++ K + G + ED +V +
Sbjct: 122 DDELKANIQDVEKDEDGKEHK-----DTGEEVEDGKIEEEGLNEKPGTAKSEDAEVSKDE 176
Query: 123 EVKEDKKVNEGGDIKEEKKADEGEKLKEDKKDDAAV--KIKEDKKVNEGEE--LKEEKKA 178
E K D + E G KEE DE E+ K+DK+ D ++KE K E ++ KEE+
Sbjct: 177 EEKGDNEKGEDG--KEE--GDEKEEEKDDKEGDTGTEKEVKEQNKEAEEDDGKCKEEENK 232
Query: 179 DEG------EKLKEDKKDDAGVEIIEDKKVNEGEELEEEKKAEGEE-LKEDKKVDAGDEI 231
+ G E KED ++ G E + ++ EG+ E+ K+ EE KE + + G E
Sbjct: 233 EVGKEGQPEEDGKEDLHEEVGKEDLHEEDGKEGQPEEDGKEIHHEEDGKEGQPEEDGKEY 292
Query: 232 --EEDKKDDNGFEDDKLSEETELSKEERESVEAKKPELDAMDEESILE--GK-----DEG 282
EED ++ ED K + E KE++ + K+ + +E E GK ++G
Sbjct: 293 LHEEDGEEGQPKEDQKEGQPEEDGKEDQPEEDGKEGQCKEDGKEGHHEEGGKEDLHEEDG 352
Query: 283 SEKEKSQKDREDDKDK---VDNKSNEENIKVEKRLKKRGKGKVNGE 325
EK+ ++DR+++ ++ VD S+E ++ E+ + K +GE
Sbjct: 353 KEKDGGKEDRKEEGEQEVAVDEGSDENKVEAEEEGAENKDFKQDGE 398
Score = 92.4 bits (228), Expect = 4e-18
Identities = 107/393 (27%), Positives = 179/393 (45%), Gaps = 51/393 (12%)
Query: 14 DLEPKGG----KIFEDNAVQDLKEDGIKAMEVDKKADGEEVLEMDKLADDGDVVTENAIK 69
+L+PK K N V++ K+ + K D ++ M+ + + E I
Sbjct: 31 ELKPKRASTSRKTKTTNVVEENKDASTIPIPETKPEDVKDECNMENAENGEAKIMEAPIP 90
Query: 70 AGDGEGIKE---DEKVNEGKEIKEDKQAD-EGEELKED----KKDNGGEERKEDKKVDVG 121
+ E +KE ++ +G E KE A+ + +ELK + +KD G+E K D G
Sbjct: 91 KMEAEEVKEQINEDTEEDGGEKKEAVAAEAKDDELKANIQDVEKDEDGKEHK-----DTG 145
Query: 122 QEVKEDKKVNEGGDIKEEKKADEGEKLKEDKKDDAAVKIKEDKKVNEGEELKEEKKADEG 181
+EV++ K EG + K E ++ +D+++ + ED K EG+E +EEK EG
Sbjct: 146 EEVEDGKIEEEGLNEKPGTAKSEDAEVSKDEEEKGDNEKGEDGK-EEGDEKEEEKDDKEG 204
Query: 182 ---------EKLKEDKKDDAGVEIIEDKKVN-EGEELEEEKKAEGEEL-KEDKKVDAGDE 230
E+ KE ++DD + E+K+V EG+ E+ K+ EE+ KED + G E
Sbjct: 205 DTGTEKEVKEQNKEAEEDDGKCKEEENKEVGKEGQPEEDGKEDLHEEVGKEDLHEEDGKE 264
Query: 231 --IEEDKKDDNGFEDDKLSEETELSKE--ERESVEAKKPELDAMDEESILEGKDEGSEKE 286
EED K+ + ED K + E KE E E +P+ D + + +GK++ E++
Sbjct: 265 GQPEEDGKEIHHEEDGKEGQPEEDGKEYLHEEDGEEGQPKEDQKEGQPEEDGKEDQPEED 324
Query: 287 -KSQKDREDDKDKVDNKSNEENIKVEKRLKKRGKGKVNGENVKKKMKELKKIEDIPEAKD 345
K + +ED K+ + +E++ E GK K G+ ED E +
Sbjct: 325 GKEGQCKEDGKEGHHEEGGKEDLHEED-----GKEKDGGK------------EDRKEEGE 367
Query: 346 ESIEKERSRDEEVGDKEKVGGENVKKKMKELKE 378
+ + + DE + E+ G EN K KE
Sbjct: 368 QEVAVDEGSDENKVEAEEEGAENKDFKQDGEKE 400
Score = 75.1 bits (183), Expect = 7e-13
Identities = 85/329 (25%), Positives = 147/329 (43%), Gaps = 49/329 (14%)
Query: 116 KKVDVGQEVKEDKKVNEGGD-----IKEEKKADEGEKLKEDKKDDAAVKIKEDKKVN-EG 169
K+ ++ K V E D I E K D ++ + ++ KI E E
Sbjct: 35 KRASTSRKTKTTNVVEENKDASTIPIPETKPEDVKDECNMENAENGEAKIMEAPIPKMEA 94
Query: 170 EELKEEKKADEGEKLKEDKKDDAGVEIIEDKKVNEGEELEEEKKAEGEELKEDKK----V 225
EE+KE+ + ED ++D G E K+ E ++E KA +++++D+
Sbjct: 95 EEVKEQ--------INEDTEEDGG----EKKEAVAAEAKDDELKANIQDVEKDEDGKEHK 142
Query: 226 DAGDEIEEDKKDDNGFEDDK---LSEETELSKEERESVEAKK-----PELDAMDEESILE 277
D G+E+E+ K ++ G + SE+ E+SK+E E + +K E D +EE +
Sbjct: 143 DTGEEVEDGKIEEEGLNEKPGTAKSEDAEVSKDEEEKGDNEKGEDGKEEGDEKEEEKDDK 202
Query: 278 GKDEGSEKEKSQKDREDDKDKVDNKSNEENIK---VEKRLKKRGKGKVNGENVKKKMKEL 334
D G+EKE ++++E ++D D K EE K E + ++ GK ++ E K+ + E
Sbjct: 203 EGDTGTEKEVKEQNKEAEED--DGKCKEEENKEVGKEGQPEEDGKEDLHEEVGKEDLHEE 260
Query: 335 KKIEDIPEAKDESIEKERSRDEEVGDKEKVGGENVKKK-------MKELKEAEPTTPTTN 387
E PE + I E D + G E+ G E + ++ ++ KE +P
Sbjct: 261 DGKEGQPEEDGKEIHHE--EDGKEGQPEEDGKEYLHEEDGEEGQPKEDQKEGQP-----E 313
Query: 388 RPVRERKSVERLVESYDRDASKEFQIEEG 416
+E + E E ++ KE EEG
Sbjct: 314 EDGKEDQPEEDGKEGQCKEDGKEGHHEEG 342
Score = 61.6 bits (148), Expect = 8e-09
Identities = 63/224 (28%), Positives = 102/224 (45%), Gaps = 25/224 (11%)
Query: 7 DDSSEKKDLEPKGGKIFEDNAVQDLKEDGIKAMEVDKKADGEEVLEMDKLA---DDGDVV 63
++ EK+ E K K + +++KE +A E D K EE E+ K +DG
Sbjct: 190 EEGDEKE--EEKDDKEGDTGTEKEVKEQNKEAEEDDGKCKEEENKEVGKEGQPEEDGKED 247
Query: 64 TENAIKAGD--GEGIKEDEKVNEGKEIKEDKQADEG---EELKEDKKDNGGEERKEDKKV 118
+ D E KE + +GKEI ++ EG E+ KE + GEE
Sbjct: 248 LHEEVGKEDLHEEDGKEGQPEEDGKEIHHEEDGKEGQPEEDGKEYLHEEDGEE------- 300
Query: 119 DVGQEVKEDKKVNEGGDIKEEKKADEGEKLKEDKKDDAAVKIKEDKKVNEGEELKEEKKA 178
GQ KED+K + + +E + +E K + K+D KE G+E E+
Sbjct: 301 --GQP-KEDQKEGQPEEDGKEDQPEEDGKEGQCKEDG-----KEGHHEEGGKEDLHEEDG 352
Query: 179 DEGEKLKEDKKDDAGVEIIEDKKVNEGEELEEEKKAEGEELKED 222
E + KED+K++ E+ D+ +E + EE+ AE ++ K+D
Sbjct: 353 KEKDGGKEDRKEEGEQEVAVDEGSDENKVEAEEEGAENKDFKQD 396
Score = 37.4 bits (85), Expect = 0.16
Identities = 24/72 (33%), Positives = 35/72 (48%), Gaps = 7/72 (9%)
Query: 566 KIEDSSIAEKKKTATDTESESEKDEENKEENEIDVSDKSEDEKPIKGKKHIAKQGSSRSG 625
KIE+ + EK TA ++E KDEE K +NE K ED K +K ++ + G
Sbjct: 152 KIEEEGLNEKPGTAKSEDAEVSKDEEEKGDNE-----KGEDGKEEGDEKE--EEKDDKEG 204
Query: 626 TASSRRSAKE*N 637
+ + KE N
Sbjct: 205 DTGTEKEVKEQN 216
>MDN1_YEAST (Q12019) Midasin (MIDAS-containing protein)
Length = 4910
Score = 102 bits (253), Expect = 5e-21
Identities = 130/581 (22%), Positives = 245/581 (41%), Gaps = 79/581 (13%)
Query: 71 GDGEGIKEDEK-VNEGKEIKEDKQADEGEELKEDKKDNGGEERKEDKKVDVGQEVKEDKK 129
GDGEG + + K V + +++ ED Q + E+ +D++D+ E+ + + D+ E+++
Sbjct: 4065 GDGEGAQNNNKDVEQDEDLTEDAQNENKEQQDKDERDDENEDDAVEMEGDMAGELED--- 4121
Query: 130 VNEGGDIKEEKKADEGEKLKEDKKDDAAVKIKEDKKVNEGEELKEEKKADEGEKLKEDKK 189
++ G + +E E E+L E+ D + ED +++ ++K +D ++ D+
Sbjct: 4122 LSNGEENDDEDTDSEEEELDEEIDD-----LNEDDPNAIDDKMWDDKASDNSKEKDTDQN 4176
Query: 190 DDAGVEIIEDKKVNEGEELEEEKKAEGEELKEDKKVDAGDEIEEDKKDDNGFEDDKLSEE 249
D G ED + E +E + + K G+E + D +EIE D+ + E+D +E
Sbjct: 4177 LD-GKNQEEDVQAAENDEQQRDNKEGGDE-DPNAPEDGDEEIENDENAEE--ENDVGEQE 4232
Query: 250 TELSKEERESVEAKKPELDAMD--EESILEGKDEGSEKEKSQKD-REDDKDKVDNKSNEE 306
E+ EE E +EA PE++ +D E+ L+ + E S+++ D DD +K + + +E
Sbjct: 4233 DEVKDEEGEDLEANVPEIETLDLPEDMNLDSEHEESDEDVDMSDGMPDDLNKEEVGNEDE 4292
Query: 307 NIKVEKRLKKRGKGKVNGENVKKKMKELKKIEDIPEAKDESIEKERSRDEEVGDKEKVGG 366
+K E ++ + EN D P ++++ E E + DEE G +E V
Sbjct: 4293 EVKQESGIES------DNEN------------DEPGPEEDAGETETALDEEEGAEEDVDM 4334
Query: 367 ENVKKKMKELKEAEPTTPTTNRPVRERKSVERLVESYDRDASKEFQIEEGRGTPLKNIPN 426
N + K E N P + S E E +DA+ E E+G + +
Sbjct: 4335 TNDEGKEDE----------ENGPEEQAMSDE---EELKQDAAMEENKEKGGEQNTEGLDG 4381
Query: 427 VAFKLSRRKVDDTLKFLHTILFCRRGKAAVIKKNILRFSGFVWHENEEKQMIKVKEKFDK 486
V K +D +AAV + + + +G + +E+ +
Sbjct: 4382 VEEKADTEDIDQ--------------EAAVQQDSGSKGAGADATDTQEQDDVGGSGTTQN 4427
Query: 487 CNKEKLLEFSDLLDVPVGNANTRKEDIIA--KLIDFLVAPQVTKSVLLAEQEKSAKEKRI 544
+E D DV N +R+E A +L D + + + Q +++ +
Sbjct: 4428 TYEE------DQEDVTKNNEESREEATAALKQLGDSMKEYHRRRQDIKEAQTNGEEDENL 4481
Query: 545 AKQGS--------TGSGTPTSRRSAKSRKKIEDSSIAEKKKTATDTESESEKDEENKEEN 596
K G+ T T ++ S + + +I E D E + +E E+
Sbjct: 4482 EKNNERPDEFEHVEGANTETDTQALGSATQDQLQTIDEDMAIDDDREEQEVDQKELVEDA 4541
Query: 597 EIDVSDKSEDEKPIKGKKHIAKQ--GSSRSGTASSRRSAKE 635
+ + D E+E H A S +SG R+S ++
Sbjct: 4542 DDEKMDIDEEEMLSDIDAHDANNDVDSKKSGFIGKRKSEED 4582
Score = 102 bits (253), Expect = 5e-21
Identities = 112/440 (25%), Positives = 202/440 (45%), Gaps = 68/440 (15%)
Query: 7 DDSSEKKDLEPKGGKIFEDNAVQDLKEDGIKAMEVDKKADGEEVLEMDKLADDGDVVTEN 66
DD +E +E +G E + + +E+ D+ D EE E+D+ DD + N
Sbjct: 4101 DDENEDDAVEMEGDMAGELEDLSNGEEND------DEDTDSEEE-ELDEEIDDLNEDDPN 4153
Query: 67 AI-------KAGDGEGIKEDEKVNEGKEIKEDKQADEGEELKEDKKDNGGEERKEDKKVD 119
AI KA D K+ ++ +GK +ED QA E +E + D K+ G E+ + D
Sbjct: 4154 AIDDKMWDDKASDNSKEKDTDQNLDGKNQEEDVQAAENDEQQRDNKEGGDEDPNAPE--D 4211
Query: 120 VGQEVKEDKKVNEGGDI---KEEKKADEGEKLKEDKKDDAAVKIKEDKKVNEGEELKEEK 176
+E++ D+ E D+ ++E K +EGE L+ + + + + ED ++ E +
Sbjct: 4212 GDEEIENDENAEEENDVGEQEDEVKDEEGEDLEANVPEIETLDLPEDMNLD-----SEHE 4266
Query: 177 KADEGEKLKEDKKDDAGVEIIEDKKVNEGEELEEEKKAEGEELKED--KKVDAGDEIEED 234
++DE + + DD E + NE EE+++E E + ++ + DAG E E
Sbjct: 4267 ESDEDVDMSDGMPDDLNKEEVG----NEDEEVKQESGIESDNENDEPGPEEDAG-ETETA 4321
Query: 235 KKDDNGFEDDKLSEETELSKEERESVEAKKPELDAM-DEESILEGKDEGSEKEKSQKDRE 293
++ G E+D +++ +E + E PE AM DEE + + KEK +
Sbjct: 4322 LDEEEGAEED-----VDMTNDEGKEDEENGPEEQAMSDEEELKQDAAMEENKEKGGEQNT 4376
Query: 294 DDKDKVDNKSNEENIKVEKRLKK----RGKG----------KVNGENVKKKMKELKKIED 339
+ D V+ K++ E+I E +++ +G G V G + E + ED
Sbjct: 4377 EGLDGVEEKADTEDIDQEAAVQQDSGSKGAGADATDTQEQDDVGGSGTTQNTYE-EDQED 4435
Query: 340 IPEAKDESIEKERSRDEEVGDKEKVGGENVKKKMKELKEAEPTTPTTNRPVRERKSVERL 399
+ + +ES E+ + +++GD K ++ +++KEA+ TN E +++E+
Sbjct: 4436 VTKNNEESREEATAALKQLGDSMK----EYHRRRQDIKEAQ-----TNG--EEDENLEKN 4484
Query: 400 VESYDRDASKEFQIEEGRGT 419
E D EF+ EG T
Sbjct: 4485 NERPD-----EFEHVEGANT 4499
Score = 88.6 bits (218), Expect = 6e-17
Identities = 85/363 (23%), Positives = 179/363 (48%), Gaps = 24/363 (6%)
Query: 11 EKKDLEPKGGKIFEDNAVQDLKEDGIKAMEVDKKADGEEVLEMDKLADDGDVVTENAIKA 70
+ K+L+ +G + + Q+ +D + ++ + A E + DK D+ D E+
Sbjct: 4054 DDKNLQ-EGTGLGDGEGAQNNNKDVEQDEDLTEDAQNENKEQQDK--DERDDENEDDAVE 4110
Query: 71 GDGEGIKEDEKVNEGKEIKEDKQADEGEELKEDKKD------NGGEERKEDKKVDVGQEV 124
+G+ E E ++ G+E ++ E EEL E+ D N +++ D K +
Sbjct: 4111 MEGDMAGELEDLSNGEENDDEDTDSEEEELDEEIDDLNEDDPNAIDDKMWDDKASDNSKE 4170
Query: 125 KEDKKVNEGGDIKEEKKADEGEKLKEDKK----DDAAVKIKEDKKVNEGEELKEEKKADE 180
K+ + +G + +E+ +A E ++ + D K +D D+++ E +EE D
Sbjct: 4171 KDTDQNLDGKNQEEDVQAAENDEQQRDNKEGGDEDPNAPEDGDEEIENDENAEEEN--DV 4228
Query: 181 GEKLKEDKKDDAGVEIIEDKKVNEGEELEEEKKAEGEELKEDKKVDAGDEIEED-KKDDN 239
GE+ +++ KD+ G ++ + E +L E+ + E + D+ VD D + +D K++
Sbjct: 4229 GEQ-EDEVKDEEGEDLEANVPEIETLDLPEDMNLDSEHEESDEDVDMSDGMPDDLNKEEV 4287
Query: 240 GFEDDKLSEETELSKEERESVEAKKPELDAMDEESILEGKDEGSEKEKSQKDREDDKDKV 299
G ED+++ +E+ + + + PE DA + E+ L+ ++EG+E++ + E +D+
Sbjct: 4288 GNEDEEVKQESGIESDNEN--DEPGPEEDAGETETALD-EEEGAEEDVDMTNDEGKEDE- 4343
Query: 300 DNKSNEENIKVEKRLKKRGKGKVNGENVKKKMKE-LKKIEDIPEAKDESIEKERSRDEEV 358
+N E+ + E+ LK+ + N E ++ E L +E+ +A E I++E + ++
Sbjct: 4344 ENGPEEQAMSDEEELKQDAAMEENKEKGGEQNTEGLDGVEE--KADTEDIDQEAAVQQDS 4401
Query: 359 GDK 361
G K
Sbjct: 4402 GSK 4404
Score = 74.7 bits (182), Expect = 9e-13
Identities = 101/473 (21%), Positives = 215/473 (45%), Gaps = 78/473 (16%)
Query: 5 HLDDSSEKKDLEPKGGKIFEDNAVQDLKEDGIKAMEVDKKADGEEVLEMDKLADDGDVV- 63
+LD ++++D++ D +D KE G + + + DG+E +E D+ A++ + V
Sbjct: 4176 NLDGKNQEEDVQAAEN----DEQQRDNKEGGDE--DPNAPEDGDEEIENDENAEEENDVG 4229
Query: 64 -TENAIKAGDGEGIK-------------------------EDEKVNEGK--EIKEDKQAD 95
E+ +K +GE ++ ED +++G ++ +++ +
Sbjct: 4230 EQEDEVKDEEGEDLEANVPEIETLDLPEDMNLDSEHEESDEDVDMSDGMPDDLNKEEVGN 4289
Query: 96 EGEELKEDKKDNGGEERKEDKKVDVGQEVKEDKKVNEGGDIKEEKKADEGEKLKEDKKDD 155
E EE+K++ E E + E + EG + + DEG KED+++
Sbjct: 4290 EDEEVKQESGIESDNENDEPGPEEDAGETETALDEEEGAEEDVDMTNDEG---KEDEENG 4346
Query: 156 AAVKIKEDKKVNEGEELKEEKKADEGEKLKEDKKDDAGVEIIEDKKVNEGEELEEEKKAE 215
E++ +++ EELK++ +E K K +++ G++ +E+K + E++++E +
Sbjct: 4347 -----PEEQAMSDEEELKQDAAMEE-NKEKGGEQNTEGLDGVEEKA--DTEDIDQEAAVQ 4398
Query: 216 GEELKEDKKVDAGDEIEEDKKDDNG-----FEDDKLSEETELSKEERESVEAKKPEL-DA 269
+ + DA D E+D +G +E+D+ + T+ ++E RE A +L D+
Sbjct: 4399 QDSGSKGAGADATDTQEQDDVGGSGTTQNTYEEDQ-EDVTKNNEESREEATAALKQLGDS 4457
Query: 270 MDE-----ESILEGKDEGSEKEKSQK--DREDDKDKVDNKSNEENIK-----VEKRLKKR 317
M E + I E + G E E +K +R D+ + V+ + E + + + +L+
Sbjct: 4458 MKEYHRRRQDIKEAQTNGEEDENLEKNNERPDEFEHVEGANTETDTQALGSATQDQLQTI 4517
Query: 318 GKG-KVNGENVKKKMKELKKIEDIPEAKDESIEKERSRDEEVGD-----KEKVGGENVKK 371
+ ++ + ++++ + + +ED + K + E+E D + D K G K+
Sbjct: 4518 DEDMAIDDDREEQEVDQKELVEDADDEKMDIDEEEMLSDIDAHDANNDVDSKKSGFIGKR 4577
Query: 372 KMKELKEAEPTTPTTNRPVRERKSVERLVESYD---RDAS----KEFQIEEGR 417
K +E E E + + + ++ L+E+ + DAS E +EE R
Sbjct: 4578 KSEEDFENELSNEHFSADQEDDSEIQSLIENIEDNPPDASASLTPERSLEESR 4630
Score = 48.1 bits (113), Expect = 9e-05
Identities = 53/245 (21%), Positives = 110/245 (44%), Gaps = 41/245 (16%)
Query: 195 EIIEDKKVNEGEELEEEKKAEGEELKEDKKVDAGDEIEEDKKDDNGFEDDKLSEETELSK 254
E ++DK + EG L + + A+ +K V+ +++ ED +++N + DK
Sbjct: 4051 EEVDDKNLQEGTGLGDGEGAQNN----NKDVEQDEDLTEDAQNENKEQQDK--------- 4097
Query: 255 EERESVEAKKPELDAMDEESILEGK-----------DEGSEKEKSQKD------REDDKD 297
+ER+ + E DA++ E + G+ DE ++ E+ + D EDD +
Sbjct: 4098 DERDD----ENEDDAVEMEGDMAGELEDLSNGEENDDEDTDSEEEELDEEIDDLNEDDPN 4153
Query: 298 KVDNKSNEENIKVEKRLKKRGKGKVNGENVKKKMKELKKIE---DIPEAKDESIEKERSR 354
+D+K ++ + K + ++G+N ++ ++ + E D E DE
Sbjct: 4154 AIDDKMWDDKASDNSKEKDTDQ-NLDGKNQEEDVQAAENDEQQRDNKEGGDEDPNAPEDG 4212
Query: 355 DEEVGDKEKVGGEN-VKKKMKELKEAEPTTPTTNRPVRERKSV--ERLVESYDRDASKEF 411
DEE+ + E EN V ++ E+K+ E N P E + + ++S ++ ++
Sbjct: 4213 DEEIENDENAEEENDVGEQEDEVKDEEGEDLEANVPEIETLDLPEDMNLDSEHEESDEDV 4272
Query: 412 QIEEG 416
+ +G
Sbjct: 4273 DMSDG 4277
>NFM_MOUSE (P08553) Neurofilament triplet M protein (160 kDa
neurofilament protein) (Neurofilament medium
polypeptide) (NF-M)
Length = 848
Score = 99.0 bits (245), Expect = 4e-20
Identities = 103/393 (26%), Positives = 185/393 (46%), Gaps = 40/393 (10%)
Query: 11 EKKDLEPKGGKIFEDNAVQDLKEDGIKAMEVDKKADGEEVLEMDKLADDGDVVTENAIKA 70
EK ++E I E+ A KE+ +A E +++ + E+ A + + E K
Sbjct: 464 EKSEMEETLTAIAEELAAS-AKEEKEEAEEKEEEPEAEKSPVKSPEAKEEE---EEGEKE 519
Query: 71 GDGEGIKEDEKVNEGKEIKEDKQADEGEELKE--DKKDNGGEERKEDKKVDVGQ----EV 124
+ EG +E+E+ +EG +K D QA+EG KE +KD G +E +E + G+ E
Sbjct: 520 EEEEGQEEEEEEDEG--VKSD-QAEEGGSEKEGSSEKDEGEQEEEEGETEAEGEGEEAEA 576
Query: 125 KEDKKVN---EGGDIKEEKKADEGEKLKE--DKKDDAAVKIKEDKKVNEGEELKEEKKAD 179
KE+KK+ E +KEE K ++ EK K K VK K + K +GE+ +EEK +
Sbjct: 577 KEEKKIEGKVEEVAVKEEIKVEKPEKAKSPMPKSPVEEVKPKPEAKAGKGEQKEEEKVEE 636
Query: 180 EGEKLKEDKKDDAGVEIIEDKKVNEGEELEEE----KKAEGEELKEDKKVDAGDEIEEDK 235
E +++ ++ + VE E+K + ++ + E +KA E + K V +E+D
Sbjct: 637 EKKEVTKESPKEEKVEKKEEKPKDVADKKKAESPVKEKAVEEVITISKSVKV--SLEKDT 694
Query: 236 KDDNGFEDDKLSEETELSKEERESVEAKKPELDAMDEESILEGKDEGSEKEKSQ-----K 290
K++ +K+ E+ E E + P+ ++ E+ + G+ EG E+E+ +
Sbjct: 695 KEEKPQPQEKVKEKAEEEGGSEEEGSDRSPQ-ESKKEDIAINGEVEGKEEEEQETQEKGS 753
Query: 291 DREDDKDKVDNKSNEENIKVEKRLKKRGKGKVNGENVKKKMKELKKIEDIPEAKDESIEK 350
RE++K V N + V +K+G+ ++ K+ KK+E I + K
Sbjct: 754 GREEEKGVVTN-----GLDVSPAEEKKGE-----DSSDDKVVVTKKVEKITSEGGDGATK 803
Query: 351 ERSRDEEVGDKEKVGGENVKKKMKELKEAEPTT 383
++ V K + E ++K+ K+ E T
Sbjct: 804 YITKSVTVTQKVEEHEETFEEKLVSTKKVEKVT 836
Score = 79.3 bits (194), Expect = 4e-14
Identities = 84/349 (24%), Positives = 152/349 (43%), Gaps = 60/349 (17%)
Query: 7 DDSSEKKDLEPKGGKIFEDNAVQDLKEDGIKAMEVDKKADGEEVLEMDKLADDGDVVTEN 66
+D K D +GG E ++ +D E + E + + +GEE ++ +G V
Sbjct: 531 EDEGVKSDQAEEGGSEKEGSSEKDEGEQEEEEGETEAEGEGEEAEAKEEKKIEGKV---- 586
Query: 67 AIKAGDGEGIKEDEKVNEGKEIKEDKQADEGEEL--KEDKKDNGGEERKEDKKVDVGQEV 124
+ +KE+ KV + ++ K EE+ K + K GE+++E+K + +EV
Sbjct: 587 -----EEVAVKEEIKVEKPEKAKSPMPKSPVEEVKPKPEAKAGKGEQKEEEKVEEEKKEV 641
Query: 125 KEDKKVNEGGDIKEEKKADEGEKLK-----EDKKDDAAVKIKEDKKVNEGEELKEEKKAD 179
++ E + KEEK D +K K ++K + + I + KV+ ++ KEEK
Sbjct: 642 TKESPKEEKVEKKEEKPKDVADKKKAESPVKEKAVEEVITISKSVKVSLEKDTKEEKPQP 701
Query: 180 EGEKLKEDKKDDAGVEIIEDKKVNEGEELEEEKKAEGEELKEDKKVDAGDEIEEDKKDDN 239
+ EK+KE +++ G E EG + ++ E KED ++ E +E
Sbjct: 702 Q-EKVKEKAEEEGGSE-------EEGSD-----RSPQESKKEDIAINGEVEGKE------ 742
Query: 240 GFEDDKLSEETELSKEERESVEAKKPELDAMDEESILEGKDEGSEKEKSQKDREDDKDKV 299
E+++ ++E +EE + V + G D +EK +D DDK V
Sbjct: 743 --EEEQETQEKGSGREEEKGV--------------VTNGLDVSPAEEKKGEDSSDDKVVV 786
Query: 300 DNKSNEENIKVEKRLKKRGKGKVNGENVKKKMKELKKIEDIPEAKDESI 348
KVEK + G G + + K + +K+E+ E +E +
Sbjct: 787 TK-------KVEKITSEGGDGAT--KYITKSVTVTQKVEEHEETFEEKL 826
Score = 75.1 bits (183), Expect = 7e-13
Identities = 74/300 (24%), Positives = 134/300 (44%), Gaps = 44/300 (14%)
Query: 147 KLKEDKKDDAAVKIKEDKKVNEGEELKEEKKADEGEKLKEDKKDDAGVEIIEDKKVNEGE 206
K+++ K + +K++ EE K E + E E+ ++ E+K+ E E
Sbjct: 434 KIQKTKVEAPKLKVQHKFVEEIIEETKVEDEKSEMEETLTAIAEELAASAKEEKE--EAE 491
Query: 207 ELEEEKKAE-----GEELKEDKKVDAGDEIEEDKKDDNGFEDDKLSEETELSKEERESVE 261
E EEE +AE E KE+++ +E EE ++++ ++ S++ E E+E
Sbjct: 492 EKEEEPEAEKSPVKSPEAKEEEEEGEKEEEEEGQEEEEEEDEGVKSDQAEEGGSEKEG-S 550
Query: 262 AKKPELDAMDEESILEGKDEGSEKEKSQKDREDDKDKVDNKSNEENIKVEKRLK------ 315
++K E + +EE E + EG E E K+ + + KV+ + +E IKVEK K
Sbjct: 551 SEKDEGEQEEEEGETEAEGEGEEAEA--KEEKKIEGKVEEVAVKEEIKVEKPEKAKSPMP 608
Query: 316 -------------KRGKGKVNGENVKKKMKELKKIEDIPEAKDESIEKERSRDEEVGDKE 362
K GKG+ + ++K++E KK K+E +EK+ + ++V DK+
Sbjct: 609 KSPVEEVKPKPEAKAGKGE---QKEEEKVEEEKKEVTKESPKEEKVEKKEEKPKDVADKK 665
Query: 363 KVGGENVKKKMKEL------------KEAEPTTPTTNRPVRERKSVERLVESYDRDASKE 410
K +K ++E+ K+ + P V+E+ E E D S +
Sbjct: 666 KAESPVKEKAVEEVITISKSVKVSLEKDTKEEKPQPQEKVKEKAEEEGGSEEEGSDRSPQ 725
Score = 57.8 bits (138), Expect = 1e-07
Identities = 129/657 (19%), Positives = 249/657 (37%), Gaps = 109/657 (16%)
Query: 29 QDLKEDGIKAMEVDKKADG-------------EEVLEMDKLADDGDVVTENA--IKAGDG 73
+D++E + +E+DKK EEV ++ + E +K
Sbjct: 206 KDIEESSMVKVELDKKVQSLQDEVAFLRRNHEEEVADLLAQIQASHITVERKDYLKTDIS 265
Query: 74 EGIKEDEKVNEGKEIKEDKQADEGEELKEDKKDNGGEERKEDKKVDVGQEVKEDKKVNEG 133
+KE E + QA+E + + K E+ KE + +E+ E ++ +
Sbjct: 266 TALKEIRSQLECHSDQNMHQAEEWFKCRYAKLTEAAEQNKEAIR-SAKEEIAEYRRQLQS 324
Query: 134 GDIKEEKKADEGEKLKEDKKDDAAVKIKEDKKVNEG--EELKEEKKADEGEKLKE----- 186
I+ E E L E + D + D + ++L+ E + + E +
Sbjct: 325 KSIELESVRGTKESL-ERQLSDIEERHNHDLSSYQDTIQQLENELRGTKWEMARHLREYQ 383
Query: 187 ---DKKDDAGVEIIEDKKVNEGEELEEEKKAEGEE----LKEDKKVDAGDEIEEDK---- 235
+ K +EI +K+ EGEE + V +I++ K
Sbjct: 384 DLLNVKMALDIEIAAYRKLLEGEETRFSTFSGSITGPLYTHRQPSVTISSKIQKTKVEAP 443
Query: 236 --KDDNGFEDDKLSEETELSKEERESVEAKKPELDAMDEESILEGKDEGSEKEKSQKDRE 293
K + F ++ + EET++ E+ E E L A+ EE K+E E E+ +++ E
Sbjct: 444 KLKVQHKFVEE-IIEETKVEDEKSEMEET----LTAIAEELAASAKEEKEEAEEKEEEPE 498
Query: 294 DDKDKVDN-KSNEENIKVEKRLKKRGKGKVNGENVKKKMKELKKIEDIPEAKDESIEKER 352
+K V + ++ EE + EK ++ G+ + E+ K + A++ EKE
Sbjct: 499 AEKSPVKSPEAKEEEEEGEKEEEEEGQEEEEEEDEGVKSDQ---------AEEGGSEKEG 549
Query: 353 SRDEEVGDKEKVGGENVKKKMKELKEAEPTTPTTNRPVRERKSVERLVESYDRDASKEFQ 412
S +++ G++E+ GE + E EA +E K +E VE + +
Sbjct: 550 SSEKDEGEQEEEEGETEAEGEGEEAEA-----------KEEKKIEGKVEEVAVKEEIKVE 598
Query: 413 IEEGRGTPLKNIPNVAFKLSRRKVDDTLKFLHTILFCRRGKAAVIKKNILRFSGFVWHEN 472
E +P+ P K + GK +
Sbjct: 599 KPEKAKSPMPKSPVEEVKPKPE--------------AKAGKGE--------------QKE 630
Query: 473 EEKQMIKVKEKFDKCNKEKLLEFSDLLDVPVGNANTRKEDIIAKLIDFLVAPQVTKSVLL 532
EEK + KE + KE+ +E + V + + + K ++ ++ ++KSV +
Sbjct: 631 EEKVEEEKKEVTKESPKEEKVEKKEEKPKDVADKKKAESPVKEKAVEEVIT--ISKSVKV 688
Query: 533 AEQEKSAKEKRIAKQGSTGSGTPTSRRSAKSRKKIEDSSIAEKKKTATDTESESEKDEEN 592
+ EK KE++ Q K ++K E+ +E++ +D + K E+
Sbjct: 689 S-LEKDTKEEKPQPQ-------------EKVKEKAEEEGGSEEE--GSDRSPQESKKEDI 732
Query: 593 KEENEIDVSDKSEDEKPIKGKKHIAKQGSSRSGTASSRRSAKE*NIFQKERIRCTKQ 649
E++ ++ E E KG ++G +G S K+ +++ TK+
Sbjct: 733 AINGEVEGKEEEEQETQEKGSGREEEKGVVTNGLDVSPAEEKKGEDSSDDKVVVTKK 789
Score = 37.7 bits (86), Expect = 0.12
Identities = 125/686 (18%), Positives = 259/686 (37%), Gaps = 107/686 (15%)
Query: 167 NEGEELK--EEKKADEGEKL----KEDKKDDAGVEIIEDKKVNEGEELEEEKKAEGEELK 220
NE E+L+ ++ A EK+ +++K+ +A ++ + K+ + + L + E EL+
Sbjct: 98 NEKEQLQGLNDRFAGYIEKVHYLEQQNKEIEAEIQALRQKQASHAQ-LGDAYDQEIRELR 156
Query: 221 EDKKVDAGDEIEEDKKDDNGFED-----DKLSEETELSKEERESVEAKKPELDAMDEESI 275
++ ++ + D+ ED ++ EE L + ++ A + +++ +
Sbjct: 157 ATLEMVNHEKAQVQLDSDHLEEDIHRLKERFEEEARLRDDTEAAIRALRKDIEESSMVKV 216
Query: 276 -LEGKDEGSEKEKSQKDREDDKDKVD--NKSNEENIKVEKR----------LKK-RGKGK 321
L+ K + + E + R +++ D + +I VE++ LK+ R + +
Sbjct: 217 ELDKKVQSLQDEVAFLRRNHEEEVADLLAQIQASHITVERKDYLKTDISTALKEIRSQLE 276
Query: 322 VNGENVKKKMKELKKIE--DIPEAKDESIEKERSRDEEVGDKEKVGGENVKKKMKELKEA 379
+ + + +E K + EA +++ E RS EE+ + + ++ K EL+
Sbjct: 277 CHSDQNMHQAEEWFKCRYAKLTEAAEQNKEAIRSAKEEIAEYRR----QLQSKSIELESV 332
Query: 380 EPTTPTTNRPVRERKSVERLVESYDRDASKEFQIEEGRGTP---------LKNIPNVAFK 430
T + R + + + S +D ++ + E RGT +++ NV
Sbjct: 333 RGTKESLERQLSDIEERHNHDLSSYQDTIQQLE-NELRGTKWEMARHLREYQDLLNVKMA 391
Query: 431 LS------RRKVDDTLKFLHTILFCRRGKAAVIKKNILRFSGFVWHENEEKQMIKVKEKF 484
L R+ ++ T G ++ + S + E +KV+ KF
Sbjct: 392 LDIEIAAYRKLLEGEETRFSTFSGSITGPLYTHRQPSVTISSKIQKTKVEAPKLKVQHKF 451
Query: 485 DKCNKEKLLEFSDLLDVPVGNANTRKEDIIAKLIDFLVAPQVTKSVLLAEQEKSAKEKRI 544
E+++E T+ ED +++ + L A + E+++ A+EK
Sbjct: 452 ----VEEIIE------------ETKVEDEKSEMEETLTAIAEELAASAKEEKEEAEEKEE 495
Query: 545 AKQGSTGSGTPTSRRSAKSRKKIEDSSIAEKKKTATDTESESEKDE------------EN 592
+ + KS + E+ EK++ E E E+DE E
Sbjct: 496 EPEAE--------KSPVKSPEAKEEEEEGEKEEEEEGQEEEEEEDEGVKSDQAEEGGSEK 547
Query: 593 KEENEIDVSDKSEDEKPIKGKKHIAKQGSSRSGTASSRRSAKE*NIFQKERIRCTKQSKE 652
+ +E D ++ E+E G+ +G + K + KE I+ K K
Sbjct: 548 EGSSEKDEGEQEEEE----GETEAEGEGEEAEAKEEKKIEGKVEEVAVKEEIKVEKPEKA 603
Query: 653 SNR*NKTSLGTKANF*EAIVYTLCI*SW***WKSQGLFKEEEK*KTRKAEDLNSHQVFLQ 712
+ K+ + EA +G KEEEK + K E
Sbjct: 604 KSPMPKSPVEEVKPKPEAKA-------------GKGEQKEEEKVEEEKKEVTKE-----S 645
Query: 713 RQSRKIKNKEKSDPSDDQLRKAICVIFKKVDFNTATFADILKL-LGKQFDVDLTPRKASV 771
+ K++ KE+ +KA + +K T + +K+ L K + + V
Sbjct: 646 PKEEKVEKKEEKPKDVADKKKAESPVKEKAVEEVITISKSVKVSLEKDTKEEKPQPQEKV 705
Query: 772 KTIIQQELAKLAEEDEEREQRERRGD 797
K ++E E + Q ++ D
Sbjct: 706 KEKAEEEGGSEEEGSDRSPQESKKED 731
Score = 36.6 bits (83), Expect = 0.27
Identities = 91/480 (18%), Positives = 182/480 (36%), Gaps = 80/480 (16%)
Query: 200 KKVNEGEELEEEKKAEGEELKEDKKVDA--GDEIEEDKKDDNGFEDDKLSEETELSKEER 257
+KV+ E+ +E +AE + L++ + A GD +++ ++ L E+ E+
Sbjct: 115 EKVHYLEQQNKEIEAEIQALRQKQASHAQLGDAYDQEIRE--------LRATLEMVNHEK 166
Query: 258 ESVEAKKPELDA--------MDEESILEGKDEGSEKEKSQKDREDDKDKVDNKSNEENIK 309
V+ L+ +EE+ L E + + + E KV+ ++++
Sbjct: 167 AQVQLDSDHLEEDIHRLKERFEEEARLRDDTEAAIRALRKDIEESSMVKVELDKKVQSLQ 226
Query: 310 VEKRLKKRGK--------GKVNGENVKKKMKELKKIEDIPEAKDESIEKERSRDEEVGDK 361
E +R ++ ++ + K+ K + K+ + E D+ +
Sbjct: 227 DEVAFLRRNHEEEVADLLAQIQASHITVERKDYLKTDISTALKEIRSQLECHSDQNMHQA 286
Query: 362 EKVGGENVKKKMKELKEAEPTTPTTNRPVRERKSVERLVESYDRDA-SKEFQIEEGRGTP 420
E E K + +L EA R +E + Y R SK ++E RGT
Sbjct: 287 E----EWFKCRYAKLTEAAEQNKEAIRSAKEE------IAEYRRQLQSKSIELESVRGTK 336
Query: 421 LKNIPNVAFKLSRRKVDDTLKFLHTILFCRRGKAAVIKKNILRFSGFVW----HENEEKQ 476
+++ + R D + TI +N LR G W H E +
Sbjct: 337 -ESLERQLSDIEERHNHDLSSYQDTIQQL---------ENELR--GTKWEMARHLREYQD 384
Query: 477 MIKVKEKFDK--CNKEKLLE-----FSDLLDVPVGNANTRKEDIIAKLIDFLVAPQVTKS 529
++ VK D KLLE FS G T ++ + ++ ++ K+
Sbjct: 385 LLNVKMALDIEIAAYRKLLEGEETRFSTFSGSITGPLYTHRQPSVT------ISSKIQKT 438
Query: 530 VLLAEQ--------EKSAKEKRIAKQGSTGSGTPTSRRSAKSRKKIEDSSIAEKKKTATD 581
+ A + E+ +E ++ + S T T+ + E+ AE+K+ +
Sbjct: 439 KVEAPKLKVQHKFVEEIIEETKVEDEKSEMEETLTAIAEELAASAKEEKEEAEEKEEEPE 498
Query: 582 TES------ESEKDEENKEENEIDVSDKSEDEKPIKGKKHIAKQGSSRSGTASSRRSAKE 635
E E++++EE E+ E + + E+E+ K A++G S +S + ++
Sbjct: 499 AEKSPVKSPEAKEEEEEGEKEEEEEGQEEEEEEDEGVKSDQAEEGGSEKEGSSEKDEGEQ 558
>NFH_HUMAN (P12036) Neurofilament triplet H protein (200 kDa
neurofilament protein) (Neurofilament heavy polypeptide)
(NF-H)
Length = 1026
Score = 98.6 bits (244), Expect = 6e-20
Identities = 151/629 (24%), Positives = 251/629 (39%), Gaps = 94/629 (14%)
Query: 36 IKAMEVDKKADGEEVLEMDKLADDGDVVTENAIKAGDGEGIKEDEKVNEGKEIKEDKQAD 95
I ++ K EE +++ + ++ V+ E + + E+ E KE KE++ +
Sbjct: 429 IPSVSTHIKVKSEEKIKVVEKSEKETVIVEEQTEETQ---VTEEVTEEEEKEAKEEEGKE 485
Query: 96 EGEELKEDKKDNGGEERKEDKKVDVGQEVKEDKKVNEGGDIKEEKKADEGEKL--KEDKK 153
E E +E++ + G EE K + KE K +KEE K+ K KE+ K
Sbjct: 486 E-EGGEEEEAEGGEEETKSPPAEEAASPEKEAKS-----PVKEEAKSPAEAKSPEKEEAK 539
Query: 154 DDAAVKIKEDKKVNEGEELKEEKKADEGEKLKEDKKDDAGVEIIEDKKVNEGEELEEEKK 213
A VK E K EE K +A EK E+ K A V+ E K EE + +
Sbjct: 540 SPAEVKSPEKAKSPAKEEAKSPPEAKSPEK--EEAKSPAEVKSPEKAKSPAKEEAKSPAE 597
Query: 214 AEGEE-----LKEDKK--VDAGDEIEEDKKDDNGFEDDKLSEETELSKEERESVE-AKKP 265
A+ E +KE+ K +A ++E+ K + + ++ +KEE +S E AK P
Sbjct: 598 AKSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSP--TKEEAKSPEKAKSP 655
Query: 266 ELDAMDEESILEGKDEGSEKEKSQ-KDREDDKD--KVDNKSNEEN---IKVEKRLKKRGK 319
E E+ + ++ K++ K E K K + KS E+ +K E + ++ K
Sbjct: 656 EKAKSPEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAK 715
Query: 320 GKVNGE--NVKKKMKELKKIEDIPEAKDESIEKERSRDEEVGDKEKVGGENVKK-KMKEL 376
V E + +K +K+ PE +++E E+ EK +VK + K
Sbjct: 716 SPVKEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTP 775
Query: 377 KEAEPTTPTTNRPVRERKSVERLVESYDRDASKEFQIEEGRGTPLKNIPNVAFKLSRRKV 436
+ E +P P + + V+ V+S ++ S ++E P K IP + +V
Sbjct: 776 AKEEARSPADKFPEKAKSPVKEEVKSPEKAKSP---LKEDAKAPEKEIPK------KEEV 826
Query: 437 DDTLKFLHTILFCRRGKAAVIKKNILRFSGFVWHENEEKQMIKVKEKFDKCNKEKL---- 492
+K E E+ Q +KVKE K +EK
Sbjct: 827 KSPVK-----------------------------EEEKPQEVKVKEPPKKAEEEKAPATP 857
Query: 493 ---------LEFSDLLDVPVGNANTRKEDIIAKLIDFLVAPQVT-----KSVLLAEQEKS 538
E + + P +KE + K + V + K V E+E
Sbjct: 858 KTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVEKPKESKVEAKKEEAEDKKKVPTPEKEAP 917
Query: 539 AKEKRIAKQGSTGSGTPTSRRSAKSRKKIEDSSIAEKKKTA---TDTESESEKDEENKEE 595
AK + + + T +++ K E S AEKK+ A DT+ E K E K +
Sbjct: 918 AKVE-VKEDAKPKEKTEVAKKEPDDAKAKEPSKPAEKKEAAPEKKDTKEEKAKKPEEKPK 976
Query: 596 NEIDV--SDKSEDEKPIKGKKHIAKQGSS 622
E DK+ ++P K K A++ SS
Sbjct: 977 TEAKAKEDDKTLSKEPSKPKAEKAEKSSS 1005
Score = 84.7 bits (208), Expect = 9e-16
Identities = 80/297 (26%), Positives = 140/297 (46%), Gaps = 32/297 (10%)
Query: 76 IKEDEKVNEGKEIKEDKQADEGEELKEDKKDNGGEERKEDKKVDVGQEVKE--DKKVNEG 133
+KE+ K E + ++A E+ K +K + + + K +E + DK +
Sbjct: 732 VKEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEARSPADKFPEKA 791
Query: 134 -GDIKEEKKADEGEK--LKED---------KKDDAAVKIKEDKKVNEGEELKEEKKADE- 180
+KEE K+ E K LKED KK++ +KE++K E + + KKA+E
Sbjct: 792 KSPVKEEVKSPEKAKSPLKEDAKAPEKEIPKKEEVKSPVKEEEKPQEVKVKEPPKKAEEE 851
Query: 181 -------GEKLKEDKKDDAGVEIIEDKKVNEGEELEEEK------KAEGEELKEDKKVDA 227
E+ K+ KK++A + KV E +E EK +A+ EE ++ KKV
Sbjct: 852 KAPATPKTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVEKPKESKVEAKKEEAEDKKKVPT 911
Query: 228 GDEIEEDKKDDNGFEDDKLSEETELSKEERESVEAKKPELDAMDEESILEGKDEGSEKEK 287
++ K + ED K E+TE++K+E + +AK+P A +E+ E KD +++EK
Sbjct: 912 PEKEAPAKVEVK--EDAKPKEKTEVAKKEPDDAKAKEPSKPAEKKEAAPEKKD--TKEEK 967
Query: 288 SQKDREDDKDKVDNKSNEENIKVEKRLKKRGKGKVNGENVKKKMKELKKIEDIPEAK 344
++K E K + K +++ + E K K + + +K K +K + AK
Sbjct: 968 AKKPEEKPKTEAKAKEDDKTLSKEPSKPKAEKAEKSSSTDQKDSKPPEKATEDKAAK 1024
Score = 77.4 bits (189), Expect = 1e-13
Identities = 88/336 (26%), Positives = 139/336 (41%), Gaps = 44/336 (13%)
Query: 76 IKEDEKVNEGKEIKEDKQADEGEELKEDKKDNGGEERKEDKKVDVGQEVKE-DKKVNEGG 134
+KE+ K E + ++A E+ K K EE K +K ++ K D K E
Sbjct: 718 VKEEAKSPEKAKSPVKEEAKTPEKAKSPVK----EEAKSPEKAKSPEKAKTLDVKSPEAK 773
Query: 135 DIKEEKKADEGEKLKEDKKDDAAVKIKEDKKVNEGEELKEEKKADEGEKLKEDKKDDAGV 194
+E+ +K E K ++K +K LKE+ KA E E KK++
Sbjct: 774 TPAKEEARSPADKFPEKAKSPVKEEVKSPEKAKS--PLKEDAKAPEKEI---PKKEEVKS 828
Query: 195 EIIEDKKVNEGEELEEEKKAEGEELKEDKKVDAGDEIEEDKKDDNGFEDDKLSEETELSK 254
+ E++K E + E KKAE E+ K E+KKD K
Sbjct: 829 PVKEEEKPQEVKVKEPPKKAEEEKAPATPKT-------EEKKDS--------------KK 867
Query: 255 EERESVEAKKPELDAMDEESILEGKDEGSEKEKSQKDREDDKDKVDNKSNEENIKVEKRL 314
EE EA KP+++ E ++ + K+ K +++K+ +DK KV E KVE +
Sbjct: 868 EEAPKKEAPKPKVEEKKEPAVEKPKE---SKVEAKKEEAEDKKKVPTPEKEAPAKVEVKE 924
Query: 315 KKRGKGKV-------NGENVKKKMKELKKIEDIPEAKDESIEKERSRDEEVGDKEKVGGE 367
+ K K + K+ K +K E PE KD EK + + EE E E
Sbjct: 925 DAKPKEKTEVAKKEPDDAKAKEPSKPAEKKEAAPEKKDTKEEKAK-KPEEKPKTEAKAKE 983
Query: 368 NVKKKMKE--LKEAEPTTPTTNRPVRERKSVERLVE 401
+ K KE +AE +++ ++ K E+ E
Sbjct: 984 DDKTLSKEPSKPKAEKAEKSSSTDQKDSKPPEKATE 1019
Score = 67.4 bits (163), Expect = 1e-10
Identities = 71/258 (27%), Positives = 113/258 (43%), Gaps = 24/258 (9%)
Query: 23 FEDNAVQDLKEDGIKAMEVDKKADGEEVLEMDKLADDGDVVTENAIKAGDGEGIKEDEKV 82
F + A +KE EV + L+ D A + ++ + +K+ +KE+EK
Sbjct: 787 FPEKAKSPVKE------EVKSPEKAKSPLKEDAKAPEKEIPKKEEVKSP----VKEEEKP 836
Query: 83 NEGKEIKEDKQADEGEELKEDKKDNGGEERKEDKKVDVGQEVKEDKKVNEGGDIKEEKKA 142
E K + K+A+E + K EE+K+ KK + ++ KV EEKK
Sbjct: 837 QEVKVKEPPKKAEEEKAPATPKT----EEKKDSKKEEAPKKEAPKPKV-------EEKKE 885
Query: 143 DEGEKLKEDKKDDAAVKIKEDKKVNEGEELKEEKKADEGEKLKEDKKDDAGVEIIEDKKV 202
EK KE K +A + EDKK E + K + E K +K + + +D K
Sbjct: 886 PAVEKPKESKV-EAKKEEAEDKKKVPTPEKEAPAKVEVKEDAKPKEKTEVAKKEPDDAKA 944
Query: 203 NEGEELEEEKKAEGEELKEDKKVDAGDEIEEDKKDDNGFEDDK-LSEETELSKEERESVE 261
E + E+K+A E+ K+ K+ A E+ K + EDDK LS+E K E+
Sbjct: 945 KEPSKPAEKKEAAPEK-KDTKEEKAKKPEEKPKTEAKAKEDDKTLSKEPSKPKAEKAEKS 1003
Query: 262 AKKPELDAMDEESILEGK 279
+ + D+ E E K
Sbjct: 1004 SSTDQKDSKPPEKATEDK 1021
Score = 58.5 bits (140), Expect = 7e-08
Identities = 101/522 (19%), Positives = 206/522 (39%), Gaps = 51/522 (9%)
Query: 111 ERKEDKKVDVGQEVKEDKKVNEGGDIKEEKKADEGEKLKEDKKDDAAVKIKEDKKVNEGE 170
E ++ K DV ++E + EG ++ +++E +++ D+ +AA K+ D + E
Sbjct: 258 ETRDALKCDVTSALREIRAQLEGHAVQSTLQSEEWFRVRLDRLSEAA-KVNTDAMRSAQE 316
Query: 171 ELKEEKKADEGEKLKEDKKDDAGVEIIEDKKVNEGEELEEEKKAEGEELKEDKKVDAGDE 230
E+ E ++ + + +E ++ K + LE ++ EL++ + D
Sbjct: 317 EITEYRRQLQARTTE--------LEALKSTK----DSLERQRS----ELEDRHQADIASY 360
Query: 231 IEEDKKDDNGFEDDKLSEETELSKEERESVEAKKP-ELDAMDEESILEGKDEGSEKEKSQ 289
E ++ D + K +L +E ++ + K +++ +LEG++
Sbjct: 361 QEAIQQLDAELRNTKWEMAAQL-REYQDLLNVKMALDIEIAAYRKLLEGEECRIGFGPIP 419
Query: 290 KDREDDKDKVDNKSNEENIKVEKRLKKRGKGKVNGENVKKKMKELKKIEDIPEAKDESIE 349
+ K+ + S +K E+++K K + V+++ +E + E++ E +++ +
Sbjct: 420 FSLPEGLPKIPSVSTHIKVKSEEKIKVVEKSEKETVIVEEQTEETQVTEEVTEEEEKEAK 479
Query: 350 KERSRDEEVGDKEKVGGENVKKKMKELKEAEPTTPTTNRPVRERKSVERLVESYDRDASK 409
+E ++EE G++E+ G + K +EA PV+E +S +++ +K
Sbjct: 480 EEEGKEEEGGEEEEAEGGEEETKSPPAEEAASPEKEAKSPVKEEAKSPAEAKSPEKEEAK 539
Query: 410 ---EFQIEEGRGTPLKNIPNVAFKLSRRKVDDTLKFLHTILFCRRGKAAVIKKNILRFSG 466
E + E +P K + + ++ K+ K+ +
Sbjct: 540 SPAEVKSPEKAKSPAKEEAKSPPEAKSPEKEE-------------AKSPAEVKSPEKAKS 586
Query: 467 FVWHENEEKQMIKVKEKFDKCNKEKLLEFSDLLDVPVGNANTRKEDIIAKLIDFLVAPQV 526
E + K EK KE+ P + KE+ AK + +P+
Sbjct: 587 PAKEEAKSPAEAKSPEKAKSPVKEEAKS-------PAEAKSPVKEE--AKSPAEVKSPEK 637
Query: 527 TKSVLLAEQEKSAKEKRIAKQGSTGSGTPTSRRSAKSRKKIEDSSIAEKKKTATDTESES 586
KS E + K K K S S AKS K E S EK K+ E++S
Sbjct: 638 AKSPTKEEAKSPEKAKSPEKAKSPEKEEAKSPEKAKSPVKAEAKS-PEKAKSPVKAEAKS 696
Query: 587 EK------DEENKEENEIDVSDKSEDEKPIKGKKHIAKQGSS 622
+ EE K + K E + P K K + ++ +
Sbjct: 697 PEKAKSPVKEEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKT 738
>GARP_PLAFF (P13816) Glutamic acid-rich protein precursor
Length = 678
Score = 98.6 bits (244), Expect = 6e-20
Identities = 119/595 (20%), Positives = 252/595 (42%), Gaps = 76/595 (12%)
Query: 32 KEDGIKAMEVDKKADGEEVLEMDKLADDGDVVTENAIKAGDGEGIKEDEKVNEGKEIKED 91
++D + D + E+ D +++ N + K+D+K + K+ K++
Sbjct: 75 EKDDVPTTSNDNLKNAHNNNEISSSTDPTNIINVNDKDNENSVDKKKDKKEKKHKKDKKE 134
Query: 92 KQADEGEELKEDKKDNGGEERKEDKKVDVGQEVKEDKKVNEGGDIKEEKKADEGEK-LKE 150
K+ + ++ K+DKK+ ++ K+ KK +E E + + G K + + GE+ L E
Sbjct: 135 KKEKKDKKEKKDKKEKKHKKEKKHKKDKKKKENSEVMSLYKTGQHKPKNATEHGEENLDE 194
Query: 151 DKKDDAAVKIKEDKKVNEGEELKEEKKA---DEGEKLKEDKKDDAGVEIIEDKKVNEGEE 207
+ + + ++ + +E+ + D KD+ I EDKK + +E
Sbjct: 195 EMVSEINNNAQGGLLLSSPYQYREQGGCGIISSVHETSNDTKDNDKENISEDKKEDHQQE 254
Query: 208 L------EEEKKAEGEELKEDKKVDAGDEIEEDKKDDNGFEDDKLSEETELSKEERESVE 261
++E+K + +E+KE +K++ + +E+K+ ++ K E+ E ++E+E +
Sbjct: 255 EMLKTLDKKERKQKEKEMKEQEKIEKKKKKQEEKEKKKQEKERKKQEKKERKQKEKEMKK 314
Query: 262 AKKPELDAMDEESILEGKDEGSEKEKSQKDREDDKDKVDNKSNEENIKVEKRLKK----- 316
KK E + +E ++ +K+K K+ E+ + D S E N ++ L
Sbjct: 315 QKKIEKERKKKE------EKEKKKKKHDKENEETMQQPDQTSEETNNEIMVPLPSPLTDV 368
Query: 317 -RGKGKVNGENVKKKMKELKKIEDIPEAKDESIEKERSRDEEVGDKE-KVGGENVKKKMK 374
+ GE+ +++ KE + E E K+E ++E + EE KE K G+ K K
Sbjct: 369 TTPEEHKEGEHKEEEHKEGEHKEG--EHKEEEHKEEEHKKEEHKSKEHKSKGKKDKGKKD 426
Query: 375 ELKEAEPTTPTTNRPVRERKSVERLVESYDRDASKEFQIEEGRGTPLKNIPNVAFKLSRR 434
+ K + + V V+ ++E D+D + +E+ ++I + LS+
Sbjct: 427 KGKHKKAKKEKVKKHV-----VKNVIEDEDKDGVEIINLEDKEACEEQHITVESRPLSQP 481
Query: 435 KVDDTLKFLHTILFCRRGKAAVIKKNILRFSGFVWHENEEKQMIKVKEKFDKCNKEKLLE 494
+ C+ + E+ + K K + EK L
Sbjct: 482 Q-------------CK------------------LIDEPEQLTLMDKSKVE----EKNLS 506
Query: 495 FSDLLDVPVGNANT--RKEDIIAKLIDFLVAPQVTKSVLLAEQEKSAKEKRIAKQGSTGS 552
+ L +G N R+++ K+ A + + E++K + K + ++
Sbjct: 507 IQEQLIGTIGRVNVVPRRDNHKKKMAKIEEAELQKQKHVDKEEDKKEESKEVQEE----- 561
Query: 553 GTPTSRRSAKSRKKIEDSSIAEKKKTATDTESESEKDEENKEENEIDVSDKSEDE 607
S+ + +++E+ E+++ + E E E++EE +EE E + + EDE
Sbjct: 562 ----SKEVQEDEEEVEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEDEDEEDE 612
Score = 98.2 bits (243), Expect = 8e-20
Identities = 119/572 (20%), Positives = 239/572 (40%), Gaps = 57/572 (9%)
Query: 60 GDVVTENAIKAGDGEGIKEDEKVNEGKEIKEDKQADEGEELKEDKKDNGGEERKEDKKVD 119
G ++ E ++ + K + + E K+ K+D + LK +N + D
Sbjct: 47 GRLLNETELEKNKDDNSKSETLLKEEKDEKDDVPTTSNDNLKNAHNNN-----EISSSTD 101
Query: 120 VGQEVKEDKKVNEGG-DIKEEKKADEGEKLKEDKKDDAAVKIKEDKKVNEGEELKEEKKA 178
+ + K NE D K++KK + +K K++KK+ K K+DKK EKK
Sbjct: 102 PTNIINVNDKDNENSVDKKKDKKEKKHKKDKKEKKEKKDKKEKKDKK---------EKKH 152
Query: 179 DEGEKLKEDKKDDAGVEIIEDKKVNEGEELEEEKKAEGEELKEDKKVDAGDEIEE----- 233
+ +K K+DKK E++ K G+ + GEE +++ V + +
Sbjct: 153 KKEKKHKKDKKKKENSEVMSLYKT--GQHKPKNATEHGEENLDEEMVSEINNNAQGGLLL 210
Query: 234 ----DKKDDNGFEDDKLSEETELSKEERESVEAKKPELDAMDEESILEGKDEGSEKEKSQ 289
++ G ET ++ + + + + +E +L+ D+ K+K +
Sbjct: 211 SSPYQYREQGGCGIISSVHETSNDTKDNDKENISEDKKEDHQQEEMLKTLDKKERKQKEK 270
Query: 290 KDREDDKDKVDNKSNEENIKVEKRLKKRGKGKVNGENVKKKMKELKKIEDIPEAKDESIE 349
+ +E +K + K EE K ++ +++ + K + +K+MK+ KKIE + K+E +
Sbjct: 271 EMKEQEKIEKKKKKQEEKEKKKQEKERKKQEKKERKQKEKEMKKQKKIEKERKKKEEKEK 330
Query: 350 KERSRDEEVGDKEKVGGENVKKKMKELKEAEPTTPTTNRPVRERKSVERLVESYDRDASK 409
K++ D+E + + + ++ E+ P+ T E K E E + K
Sbjct: 331 KKKKHDKENEETMQQPDQTSEETNNEIMVPLPSPLTDVTTPEEHKEGEHKEEEHKEGEHK 390
Query: 410 EFQIEEGRGTPLKNIPNVAFKLSRRKVDDTLKFLHTILFCRRGKAAVIKKNILRFSGFVW 469
E + +E ++ + K ++ K +KK++++
Sbjct: 391 EGEHKEEEHKEEEHKKEEHKSKEHKSKGKKDKGKKDKGKHKKAKKEKVKKHVVKNV---- 446
Query: 470 HENEEKQMIKVKEKFDK--CNKEKLLEFSDLLDVPVGNANTRKEDIIAKLIDFLVAPQVT 527
E+E+K +++ DK C ++ + S L P KLID +
Sbjct: 447 IEDEDKDGVEIINLEDKEACEEQHITVESRPLSQPQ-----------CKLIDEPEQLTLM 495
Query: 528 KSVLLAEQEKSAKEKRIAKQGSTGSGTPTSRRSAKSRK--KIEDSSI---------AEKK 576
+ E+ S +E+ I G+ G RR +K KIE++ + +KK
Sbjct: 496 DKSKVEEKNLSIQEQLI---GTIGRVNVVPRRDNHKKKMAKIEEAELQKQKHVDKEEDKK 552
Query: 577 KTATDTESESEKDEENKEENEIDVSDKSEDEK 608
+ + + + ES++ +E++EE E D ++ E+E+
Sbjct: 553 EESKEVQEESKEVQEDEEEVEEDEEEEEEEEE 584
Score = 89.4 bits (220), Expect = 3e-17
Identities = 138/646 (21%), Positives = 270/646 (41%), Gaps = 112/646 (17%)
Query: 5 HLDDSSEKKDLEPKGGKIFEDNAVQDLKEDGIKAMEVDKKADGEEVLEMDKLADDGDVVT 64
H D EKK+ + K K +D + K++ K + KK + EV+ + K G
Sbjct: 128 HKKDKKEKKEKKDKKEK--KDKKEKKHKKEK-KHKKDKKKKENSEVMSLYKT---GQHKP 181
Query: 65 ENAIKAG----DGEGIKEDEKVNEGKEIKED--KQADEG--------EELKEDKKDNGGE 110
+NA + G D E + E +G + + ++G E D KDN E
Sbjct: 182 KNATEHGEENLDEEMVSEINNNAQGGLLLSSPYQYREQGGCGIISSVHETSNDTKDNDKE 241
Query: 111 ERKEDKKVDVGQEVKEDKKVNEGGDIKEEKKADEGEKLKEDKKDDAAVKIKEDKKVNEGE 170
EDKK D QE +K K + +K KE K+ + K +KK + E
Sbjct: 242 NISEDKKEDHQQEEM----------LKTLDKKERKQKEKEMKEQE-----KIEKKKKKQE 286
Query: 171 ELKEEKKADEGEKLKEDKKDDAGVEIIEDKKVNEGEELEEEKKAEGEELKEDKKVDAGDE 230
E +EKK E E+ K++KK+ + + +E++++KK E E K+++K
Sbjct: 287 E--KEKKKQEKERKKQEKKE----------RKQKEKEMKKQKKIEKERKKKEEK------ 328
Query: 231 IEEDKKDDNGFEDDKLSEETELSKEERESVEAKKPELDAMDEESILEGKDEGSEKEKSQK 290
E KK + E+++ ++ + + EE + E P + + + E EG KE+ K
Sbjct: 329 --EKKKKKHDKENEETMQQPDQTSEETNN-EIMVPLPSPLTDVTTPEEHKEGEHKEEEHK 385
Query: 291 DRE-DDKDKVDNKSNEENIKVEKRLKKRGKGKVNGENVKKKMKELKKIEDIPEAKDESIE 349
+ E + + + + EE K E+ K K K + KK + KK AK E ++
Sbjct: 386 EGEHKEGEHKEEEHKEEEHKKEEHKSKEHKSKGKKDKGKKDKGKHKK------AKKEKVK 439
Query: 350 KERSRDEEVGDKEKVGGENVKKKMKELKEAEPTTPTTNRPVRERKSVERLVESYDRDASK 409
K ++ + D++K G E + + KE E + T +RP+ + + +L++
Sbjct: 440 KHVVKN-VIEDEDKDGVEIINLEDKEACEEQHIT-VESRPLSQPQC--KLIDE------- 488
Query: 410 EFQIEEGRGTPLKNIPNVAFKLSRRKVDDTLKFLHTILFCRRGKAAVIKKNILRFSGFVW 469
P + + KV++ + L G+ V+ +
Sbjct: 489 ---------------PEQLTLMDKSKVEEKNLSIQEQLIGTIGRVNVVPR---------- 523
Query: 470 HENEEKQMIKVKEKFDKCNKEKLLEFSDLLDVPVGNANTRKEDIIAKLIDFLVAPQVTKS 529
+N +K+M K++E + K+K V +KE+ + + +
Sbjct: 524 RDNHKKKMAKIEEA--ELQKQK----------HVDKEEDKKEESKEVQEESKEVQEDEEE 571
Query: 530 VLLAEQEKSAKEKRIAKQGSTGSGTPTSRRSAKSRKKIEDSSIAEK-KKTATDTESESEK 588
V E+E+ +E+ ++ + + ED AE+ + A + E ++E+
Sbjct: 572 VEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEDEDEEDEDDAEEDEDDAEEDEDDAEE 631
Query: 589 DEENKEENEIDVSDKSEDEKPIKGKKHIAKQGSSRSGTASSRRSAK 634
D++ ++++E D + ++++ + ++ ++ S + + R++AK
Sbjct: 632 DDDEEDDDEEDDDEDEDEDEEDEEEEEEEEEESEKKIKRNLRKNAK 677
Score = 84.3 bits (207), Expect = 1e-15
Identities = 84/381 (22%), Positives = 172/381 (45%), Gaps = 60/381 (15%)
Query: 8 DSSEKKDLEPKGGKIFEDNAVQDLKEDGIKAMEVDKKADGEEVLEMDKLADDGD------ 61
+ E+K E + K + + KE+ K + K + E + + D+ +++ +
Sbjct: 301 EKKERKQKEKEMKKQKKIEKERKKKEEKEKKKKKHDKENEETMQQPDQTSEETNNEIMVP 360
Query: 62 ---VVTENAIKAGDGEGIKEDEKVNEGKEIKEDKQADEGEELKEDKKDNGGEERKEDKKV 118
+T+ EG ++E+ EG+ + + + +E +E + K+++ +E K K
Sbjct: 361 LPSPLTDVTTPEEHKEGEHKEEEHKEGEHKEGEHKEEEHKEEEHKKEEHKSKEHKSKGKK 420
Query: 119 DVGQEVKEDKKVNEGGDIKEEKKADEGEKLKEDKKDDAAVKIKEDKKVNEGEELKEE--- 175
D G K+DK ++ ++ KK ++++ KD + EDK+ E + + E
Sbjct: 421 DKG---KKDKGKHKKAKKEKVKKHVVKNVIEDEDKDGVEIINLEDKEACEEQHITVESRP 477
Query: 176 ------KKADEGEKLK--------------------------------EDKKDDAGVEII 197
K DE E+L KK A +E
Sbjct: 478 LSQPQCKLIDEPEQLTLMDKSKVEEKNLSIQEQLIGTIGRVNVVPRRDNHKKKMAKIEEA 537
Query: 198 E---DKKVNEGEELEEEKKA---EGEELKEDKKVDAGDEIEEDKKDDNGFEDDKLSEETE 251
E K V++ E+ +EE K E +E++ED++ DE EE+++++ E+++ EE E
Sbjct: 538 ELQKQKHVDKEEDKKEESKEVQEESKEVQEDEEEVEEDEEEEEEEEEEEEEEEEEEEEEE 597
Query: 252 LSKEERESVEAKKPELDAMDEESILEGKDEGSEKEKSQKDREDDKDKVDNKSNEENIKVE 311
+EE E E ++ E DA ++E E ++ +E++ ++D +++ D D +EE+ + E
Sbjct: 598 EEEEEEEEDEDEEDEDDAEEDEDDAEEDEDDAEEDDDEEDDDEEDDDEDEDEDEEDEEEE 657
Query: 312 KRLKKRGKGKVNGENVKKKMK 332
+ ++ + K+ N++K K
Sbjct: 658 EEEEEESEKKIK-RNLRKNAK 677
Score = 82.4 bits (202), Expect = 4e-15
Identities = 78/312 (25%), Positives = 154/312 (49%), Gaps = 29/312 (9%)
Query: 3 GNHLDDSSEKKDLEPKGGKIFEDNAVQDLKEDGIKAMEVDKKADGEEVLE--MDKLADDG 60
G H ++ ++++ + + K E + + K+ G K KKA E+V + + + +D
Sbjct: 392 GEHKEEEHKEEEHKKEEHKSKEHKS-KGKKDKGKKDKGKHKKAKKEKVKKHVVKNVIEDE 450
Query: 61 DVVTENAIKAGDGEGIKEDEKVNEGKEIKED--KQADEGEELKEDKKDNGGEERKEDKKV 118
D I D E +E E + + + K DE E+L K + E+K +
Sbjct: 451 DKDGVEIINLEDKEACEEQHITVESRPLSQPQCKLIDEPEQLTLMDKS-----KVEEKNL 505
Query: 119 DVGQEVKEDKKVNEGGDIKEEKKADEGEKLKEDKKDDAAVKIKEDKKVNEGEELKEEKKA 178
+ +++ + G + + D +K K K ++A ++++ K V++ E+ KEE K
Sbjct: 506 SIQEQL-----IGTIGRVNVVPRRDNHKK-KMAKIEEA--ELQKQKHVDKEEDKKEESKE 557
Query: 179 DEGEKLKEDKKDDAGVEIIEDKKVNEGEELEEEKKAEGEELKEDKKVDAGDEIEEDKKDD 238
+ E+ KE ++D+ VE E+ EEE++ E EE +E+++ + +E EE++++D
Sbjct: 558 VQ-EESKEVQEDEEEVE----------EDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEED 606
Query: 239 NGFEDDKLSEETELSKEERESVEAKKPELDAMDEESILEGKDEGSEKEKSQKDREDDKDK 298
ED+ +EE E EE E + + + DEE E +DE E E+ +++ E++ +K
Sbjct: 607 EDEEDEDDAEEDEDDAEEDEDDAEEDDDEEDDDEEDDDEDEDEDEEDEEEEEEEEEESEK 666
Query: 299 VDNKSNEENIKV 310
++ +N K+
Sbjct: 667 KIKRNLRKNAKI 678
Score = 38.9 bits (89), Expect = 0.054
Identities = 30/115 (26%), Positives = 50/115 (43%), Gaps = 7/115 (6%)
Query: 544 IAKQGSTGSGTPTSRRSAKSRKKIEDSSIAEKKKTATDTESESEKDEENKEENEIDVSDK 603
I+ T + T + + S K ED E KT D + +K++E KE+ +I+ K
Sbjct: 225 ISSVHETSNDTKDNDKENISEDKKEDHQQEEMLKTL-DKKERKQKEKEMKEQEKIEKKKK 283
Query: 604 SEDEKPIKGKKHIAKQGSSRSGTASSRRSAKE*NIFQKERIRCTKQSKESNR*NK 658
++EK K KQ R R KE + ++++I ++ KE K
Sbjct: 284 KQEEKEKK------KQEKERKKQEKKERKQKEKEMKKQKKIEKERKKKEEKEKKK 332
>IF2P_HUMAN (O60841) Eukaryotic translation initiation factor 5B
(eIF-5B) (Translation initiation factor IF-2)
Length = 1220
Score = 98.2 bits (243), Expect = 8e-20
Identities = 141/651 (21%), Positives = 268/651 (40%), Gaps = 124/651 (19%)
Query: 25 DNAVQDLKEDGIKAMEVDKKADGEEVLEMDKLA-DDGDVVTENAIKAGDGEGIKEDEKV- 82
D +++ G + +K+ G++ E K D+ D++ E + + +GIK D +
Sbjct: 20 DALAAEIEGAGAAKEQEPQKSKGKKKKEKKKQDFDEDDILKELEELSLEAQGIKADRETV 79
Query: 83 ------NEGKEIKEDKQADEGEELKEDKKDNGGEERKEDKKVDVGQEVKEDKKVNEGGDI 136
N +E + +G++ K+ D+ E EDK + K ++ G D
Sbjct: 80 AVKPTENNEEEFTSKDKKKKGQKGKKQSFDDNDSEELEDKDSKSKKTAKPKVEMYSGSDD 139
Query: 137 KEE-----KKADEGEKLKEDKK-------DDAAVKIKEDKKVNE----GEELKEEKKADE 180
++ KKA +G+ K +KK +D + KIKE ++N G+E E ++ +
Sbjct: 140 DDDFNKLPKKA-KGKAQKSNKKWDGSEEDEDNSKKIKERSRINSSGESGDESDEFLQSRK 198
Query: 181 GEKLKEDKK-----------DDAGVEI--IEDKKVNEGEELEEEKKAEGEELKEDKKVDA 227
G+K + K DDA +I + KK E+ E E+K EE + +K+
Sbjct: 199 GQKKNQKNKPGPNIESGNEDDDASFKIKTVAQKKA---EKKERERKKRDEEKAKLRKLKE 255
Query: 228 GDEIEEDKKDDNGFEDDKLSEETELSKEERESVEAKKPELDAMDEESILEGKDEGSEKEK 287
+E+E KKD + ++ K E E+V++K +D I +++
Sbjct: 256 KEELETGKKDQS-------KQKESQRKFEEETVKSKV----TVDTGVIPASEEKAETPTA 304
Query: 288 SQKDREDDKDKVDNKSNEENIKVEKRLKKRGKGKVNGENVKKKMKELKKIEDIPEAKDES 347
++ D E DK K D K + + +++ KK+G K + +++ + +LK+
Sbjct: 305 AEDDNEGDKKKKDKKKKKGEKEEKEKEKKKGPSKATVKAMQEALAKLKE----------- 353
Query: 348 IEKERSRDEEVGDKEKVGGENVKKKMKELKEAEPTTPTTNRPVRERKSVERLVESYDRDA 407
E+ER + EE ++++K L+E E +RK ERL E R+
Sbjct: 354 -EEERQKREE------------EERIKRLEELEA----------KRKEEERL-EQEKRER 389
Query: 408 SKEFQIEEGRGTPLKNIPNVAFKLSRR---KVDDTLKFLHTILFCRRGKAAVIKKNILRF 464
K Q E+ R LK + K R + + TLK L K ++ KK +
Sbjct: 390 KK--QKEKERKERLKKEGKLLTKSQREARARAEATLKLLQAQGVEVPSKDSLPKKRPIY- 446
Query: 465 SGFVWHENEEKQMIKVKEKFDKCNKEKLLEFSDLLDVPVGNANTRKEDIIAKLIDFLVAP 524
E+K+ K+ ++ + + +E ++V ++E
Sbjct: 447 --------EDKKRKKIPQQLESKEVSESMELCAAVEVMEQGVPEKEE------------- 485
Query: 525 QVTKSVLLAEQEKSAKEKRIAKQGSTGSGTPTSRRSAKSRKKIEDSSIAEKKKTATDTES 584
T + E+E+ ++ + + S T +K+E +++ + K + E
Sbjct: 486 --TPPPVEPEEEEDTEDAGLDDWEAMASDEET--------EKVEGNTVHIEVKENPEEEE 535
Query: 585 ESEKDEENKEENEIDVSDKSEDEKPIKGKKHIAKQGSSRSGTASSRRSAKE 635
E E++EE EE+E + ++ E E ++ SG ++ +KE
Sbjct: 536 EEEEEEEEDEESEEEEEEEGESEGSEGDEEDEKVSDEKDSGKTLDKKPSKE 586
Score = 94.4 bits (233), Expect = 1e-18
Identities = 102/395 (25%), Positives = 187/395 (46%), Gaps = 63/395 (15%)
Query: 9 SSEKKDLEPKGGKIFEDNAVQDLKEDGIKAMEVDKKADGEEVLEMDKLADDGDVVTENAI 68
S KK E K ED+ +++L+E ++A + KAD E V ++ + +++
Sbjct: 40 SKGKKKKEKKKQDFDEDDILKELEELSLEAQGI--KADRETVAVKPTENNEEEFTSKDKK 97
Query: 69 KAGDGEGIKEDEKVNEGKEIKEDKQA----------------DEGEELKEDKKDNGGEER 112
K G +G K+ N+ +E+ EDK + D+ ++ + K G+ +
Sbjct: 98 KKGQ-KGKKQSFDDNDSEEL-EDKDSKSKKTAKPKVEMYSGSDDDDDFNKLPKKAKGKAQ 155
Query: 113 KEDKKVDVGQE-------VKEDKKVNEGGDIKEEK----KADEGEKLKEDKK-------- 153
K +KK D +E +KE ++N G+ +E ++ +G+K + K
Sbjct: 156 KSNKKWDGSEEDEDNSKKIKERSRINSSGESGDESDEFLQSRKGQKKNQKNKPGPNIESG 215
Query: 154 ---DDAAVKIKEDKKVNEGEELKEEKKADEGEKLKEDKKDDAGVEIIEDKKVNEGEELEE 210
DDA+ KIK + ++ +E KK DE EK K K + E +E K ++ ++ E
Sbjct: 216 NEDDDASFKIKTVAQKKAEKKERERKKRDE-EKAKLRKLKEK--EELETGKKDQSKQKES 272
Query: 211 EKKAEGEELKEDKKVDAGDEIEEDKK--------DDNGFEDDKLSEETELSKEERESVEA 262
++K E E +K VD G ++K DDN E DK ++ + K E+E E
Sbjct: 273 QRKFEEETVKSKVTVDTGVIPASEEKAETPTAAEDDN--EGDKKKKDKKKKKGEKEEKEK 330
Query: 263 KKPE------LDAMDEESILEGKDEGSEKEKSQKDREDDKDKVDNK-SNEENIKVEKRLK 315
+K + + AM +E++ + K+E +++ +++R ++++ K EE ++ EKR +
Sbjct: 331 EKKKGPSKATVKAM-QEALAKLKEEEERQKREEEERIKRLEELEAKRKEEERLEQEKRER 389
Query: 316 KRGKGKVNGENVKKKMKELKKIEDIPEAKDESIEK 350
K+ K K E +KK+ K L K + A+ E+ K
Sbjct: 390 KKQKEKERKERLKKEGKLLTKSQREARARAEATLK 424
Score = 88.2 bits (217), Expect = 8e-17
Identities = 152/687 (22%), Positives = 274/687 (39%), Gaps = 160/687 (23%)
Query: 54 DKLADDGDVVTENAIKAGDGEGIKEDEKVNEGKEIKEDKQAD---------------EGE 98
D DD D+ A G G +++ + ++GK+ KE K+ D E +
Sbjct: 11 DSTKDDIDLDALAAEIEGAGAAKEQEPQKSKGKKKKEKKKQDFDEDDILKELEELSLEAQ 70
Query: 99 ELKEDKK-------DNGGEERKEDKKVDVGQEVKE------DKKVNEGGDIKEEK----- 140
+K D++ +N EE K GQ+ K+ D + E D K +K
Sbjct: 71 GIKADRETVAVKPTENNEEEFTSKDKKKKGQKGKKQSFDDNDSEELEDKDSKSKKTAKPK 130
Query: 141 -----------------KADEGEKLKEDKK-------DDAAVKIKEDKKVN----EGEEL 172
K +G+ K +KK +D + KIKE ++N G+E
Sbjct: 131 VEMYSGSDDDDDFNKLPKKAKGKAQKSNKKWDGSEEDEDNSKKIKERSRINSSGESGDES 190
Query: 173 KEEKKADEGEKLKEDKK-----------DDAGVEI--IEDKKVNEGEELEEEKKAEGEEL 219
E ++ +G+K + K DDA +I + KK E+ E E+K EE
Sbjct: 191 DEFLQSRKGQKKNQKNKPGPNIESGNEDDDASFKIKTVAQKK---AEKKERERKKRDEEK 247
Query: 220 KEDKKVDAGDEIEEDKKDDNGFEDDKLSEETELSKEERESVEAKKPELDAMDEESILEGK 279
+ +K+ +E+E KKD + ++ K E E+V++K +D I +
Sbjct: 248 AKLRKLKEKEELETGKKDQS-------KQKESQRKFEEETVKSKV----TVDTGVIPASE 296
Query: 280 DEGSEKEKSQKDREDDKDKVDNKSNEENIKVEKRLKKRGKGKVNGENVKKKMKELKKIED 339
++ ++ D E DK K D K + + +++ KK+G K + +++ + +LK+
Sbjct: 297 EKAETPTAAEDDNEGDKKKKDKKKKKGEKEEKEKEKKKGPSKATVKAMQEALAKLKE--- 353
Query: 340 IPEAKDESIEKERSRDEEVGDKEKVGGENVKKKMKELKEAEPTTPTTNRPVRERKSVERL 399
E+ER + EE ++++K L+E E +RK ERL
Sbjct: 354 ---------EEERQKREE------------EERIKRLEELE----------AKRKEEERL 382
Query: 400 VESYDRDASKEFQIEEGRGTPLKNIPNVAFKL---SRRKVDDTLKFLHTILFCRRGKAAV 456
E R+ K Q E+ R LK + K +R + + TLK L K ++
Sbjct: 383 -EQEKRERKK--QKEKERKERLKKEGKLLTKSQREARARAEATLKLLQAQGVEVPSKDSL 439
Query: 457 IKKNILRFSGFVWHENEEKQMIKVKEKFDKCNKEKLLEFSDLLDVPVGNANTRKEDIIAK 516
KK + E+K+ K+ ++ + + +E ++V ++E
Sbjct: 440 PKKRPI---------YEDKKRKKIPQQLESKEVSESMELCAAVEVMEQGVPEKEE----- 485
Query: 517 LIDFLVAPQVTKSVLLAEQEKSAKEKRIAKQGSTGSGTPTSRRSAKS----RKKIEDSSI 572
T + E+E+ ++ + + S T + + K+ +
Sbjct: 486 ----------TPPPVEPEEEEDTEDAGLDDWEAMASDEETEKVEGNTVHIEVKENPEEEE 535
Query: 573 AEKKKTATDTESESEKDEENKEE-NEIDVSDKSEDEKPIKGK---KHIAKQGSSRSGTAS 628
E+++ D ESE E++EE + E +E D D+ ++ GK K +K+ SS S S
Sbjct: 536 EEEEEEEEDEESEEEEEEEGESEGSEGDEEDEKVSDEKDSGKTLDKKPSKEMSSDSEYDS 595
Query: 629 SRRSAKE*NIFQKERIRCTKQSKESNR 655
KE + K + R K+ E ++
Sbjct: 596 DDDRTKEERAYDKAKRRIEKRRLEHSK 622
Score = 76.6 bits (187), Expect = 2e-13
Identities = 132/603 (21%), Positives = 244/603 (39%), Gaps = 127/603 (21%)
Query: 3 GNHLDDSS-----------EKKDLEPKGG--------KIFEDNAVQDLKEDGIKAMEVDK 43
GN DD+S EKK+ E K K+ E ++ K+D K E +
Sbjct: 215 GNEDDDASFKIKTVAQKKAEKKERERKKRDEEKAKLRKLKEKEELETGKKDQSKQKESQR 274
Query: 44 KADGEEVLEMDKLADDGDVVTENAIKAGDGEGIKEDEKVNEGKEIKEDKQADEGEELKED 103
K + E V K+ D V+ + KA ++D NEG + K+DK+ +GE+ +++
Sbjct: 275 KFEEETV--KSKVTVDTGVIPASEEKAETPTAAEDD---NEGDKKKKDKKKKKGEKEEKE 329
Query: 104 KKDNGGEERKEDKKVDVG----QEVKEDKKVNEGGDIKE----EKKADEGEKLKEDKKDD 155
K+ G + K + +E +E +K E IK E K E E+L+++K++
Sbjct: 330 KEKKKGPSKATVKAMQEALAKLKEEEERQKREEEERIKRLEELEAKRKEEERLEQEKRER 389
Query: 156 AAVKIKEDKK---------------------------VNEGEELKEEKKADEGEKLKEDK 188
K KE K+ +G E+ + + + EDK
Sbjct: 390 KKQKEKERKERLKKEGKLLTKSQREARARAEATLKLLQAQGVEVPSKDSLPKKRPIYEDK 449
Query: 189 KDDAGVEIIEDKKVNEGEEL------------EEEK-----KAEGEELKEDKKVDAGDEI 231
K + +E K+V+E EL E+E+ + E EE ED +D + +
Sbjct: 450 KRKKIPQQLESKEVSESMELCAAVEVMEQGVPEKEETPPPVEPEEEEDTEDAGLDDWEAM 509
Query: 232 EEDKKDDNGFEDDKLSEETELSKEERESVEAKKPELDAMDEESILEGKDEGSEKEK---- 287
D++ + E + + E + + EE E E ++ E + +EE EG+ EGSE ++
Sbjct: 510 ASDEETEK-VEGNTVHIEVKENPEEEEEEEEEEEEDEESEEEEEEEGESEGSEGDEEDEK 568
Query: 288 ----------------------SQKDREDDKDKVDNKSNEENIKVEKRLKKRGKGKVNGE 325
S+ D +DD+ K + ++ ++EKR + K VN E
Sbjct: 569 VSDEKDSGKTLDKKPSKEMSSDSEYDSDDDRTKEERAYDKAKRRIEKRRLEHSK-NVNTE 627
Query: 326 NVKKKMKELKKIEDIPEAKDESIEKERS---RDEEVGD-KEKVGGENVKKKMKELKEAEP 381
++ + + + + K + ++K R +D E G +++G NV L+
Sbjct: 628 KLRAPI--ICVLGHVDTGKTKILDKLRHTHVQDGEAGGITQQIGATNV-----PLEAINE 680
Query: 382 TTPTTNRPVRERKSVERLVESYDRDASKEFQIEEGRGTPLKNIPNVAFKLSRRKVDDTLK 441
T RE + ++ D + F RG+ L +I + + T++
Sbjct: 681 QTKMIKNFDRENVRIPGML-IIDTPGHESFSNLRNRGSSLCDIAILVVDIMHGLEPQTIE 739
Query: 442 FLHTILFCRRGKAAVIKKNILRFSGFVWHENEE--------KQMIKVKEKFDKCNKEKLL 493
++ +L ++ V I R + W ++ + KQ K++F++ K ++
Sbjct: 740 SIN-LLKSKKCPFIVALNKIDRL--YDWKKSPDSDVAATLKKQKKNTKDEFEERAKAIIV 796
Query: 494 EFS 496
EF+
Sbjct: 797 EFA 799
Score = 66.6 bits (161), Expect = 2e-10
Identities = 108/471 (22%), Positives = 192/471 (39%), Gaps = 76/471 (16%)
Query: 147 KLKEDKKDDAAVKIKEDKKVNEGEELKEEKKADEGEKLKEDKKDDAGVEIIEDKKVNEGE 206
K ++ KDD + + G ++E + +G+K KE KK D ED + E E
Sbjct: 8 KSEDSTKDDIDLDALAAEIEGAGAAKEQEPQKSKGKKKKEKKKQDFD----EDDILKELE 63
Query: 207 ELEEEKKAEGEELKEDKKVDAGDEIEEDKKDDNGFEDDKLSEETELSKEERESVEAKKPE 266
EL E + +K D++ A E ++ EE ++++ + KK
Sbjct: 64 EL----SLEAQGIKADRETVAVKPTENNE------------EEFTSKDKKKKGQKGKKQS 107
Query: 267 LDAMDEESILEGKDEGSEKEKSQK-------DREDDKDKVDNKSNEENIKVEKRLKKRGK 319
D D E LE KD S+K K D +DD +K+ K+ + ++ K+
Sbjct: 108 FDDNDSEE-LEDKDSKSKKTAKPKVEMYSGSDDDDDFNKLPKKAKGK----AQKSNKKWD 162
Query: 320 GKVNGENVKKKMKELKKIEDIPEAKDESIEKERSRDEEVGDKEKVGGENVKKKMKELKEA 379
G E+ KK+KE +I E+ DES E +SR + +++ G N++ E +A
Sbjct: 163 GSEEDEDNSKKIKERSRINSSGESGDESDEFLQSRKGQKKNQKNKPGPNIESG-NEDDDA 221
Query: 380 EPTTPTTNRPVRERKSVERLVESYDRDASKEFQIEEGRGTPLKNIPNVAFKLSRRKV-DD 438
T + E+K ER + D + +K +++E K S+RK ++
Sbjct: 222 SFKIKTVAQKKAEKKERER--KKRDEEKAKLRKLKEKEELETGKKDQSKQKESQRKFEEE 279
Query: 439 TLKFLHTILFCRRGKAAVI----KKNILRFSGFVWHENEEKQMIKVKEKFDKCNKEKLLE 494
T+K T+ VI +K + +E ++K+ K K+K +K KEK
Sbjct: 280 TVKSKVTV------DTGVIPASEEKAETPTAAEDDNEGDKKKKDKKKKKGEKEEKEK--- 330
Query: 495 FSDLLDVPVGNANTRKEDIIAKLIDFLVAPQVTKSVLLAEQEKSAKEKRIAKQGSTGSGT 554
+ P ++ +AKL + E++K +E+RI
Sbjct: 331 --EKKKGPSKATVKAMQEALAKLKE------------EEERQKREEEERI---------- 366
Query: 555 PTSRRSAKSRKKIEDSSIAEKKKTATDTESESEKDEENKEENEIDVSDKSE 605
+R + K ++ E++K + E E+ E K+E ++ + E
Sbjct: 367 ---KRLEELEAKRKEEERLEQEKRERKKQKEKERKERLKKEGKLLTKSQRE 414
Score = 65.5 bits (158), Expect = 5e-10
Identities = 111/542 (20%), Positives = 221/542 (40%), Gaps = 90/542 (16%)
Query: 137 KEEKKADEGEKLKEDKKDDAAVKIKEDKKVNEGEELKEEKKADEGEKLKEDKKDDAGVEI 196
K++K E + K+D DA E + +E ++ K + EK K+D +D ++
Sbjct: 3 KKQKNKSE-DSTKDDIDLDALAAEIEGAGAAKEQEPQKSKGKKKKEKKKQDFDEDDILKE 61
Query: 197 IEDKKV-------------------NEGEELEEEKKAEGEELKEDKKVDAGDEIEEDKKD 237
+E+ + NE E ++KK +G++ K+ D E EDK
Sbjct: 62 LEELSLEAQGIKADRETVAVKPTENNEEEFTSKDKKKKGQKGKKQSFDDNDSEELEDKDS 121
Query: 238 D------------NGFEDDKLSEETELSKEERESVEAKKPELDAMDEE------------ 273
+G +DD + +L K+ + + + D +E+
Sbjct: 122 KSKKTAKPKVEMYSGSDDD--DDFNKLPKKAKGKAQKSNKKWDGSEEDEDNSKKIKERSR 179
Query: 274 --SILEGKDEGSE-------KEKSQKDREDDKDKVDNKSNEENIKV----EKRLKKRGKG 320
S E DE E ++K+QK++ + N+ ++ + K+ +K+ +K+ +
Sbjct: 180 INSSGESGDESDEFLQSRKGQKKNQKNKPGPNIESGNEDDDASFKIKTVAQKKAEKKERE 239
Query: 321 KVNGENVKKKMKELKKIEDIPEA-KDESIEKERSRD-EEVGDKEKVGGENVKKKMKELKE 378
+ + K K+++LK+ E++ KD+S +KE R EE K KV + E K
Sbjct: 240 RKKRDEEKAKLRKLKEKEELETGKKDQSKQKESQRKFEEETVKSKVTVDTGVIPASEEKA 299
Query: 379 AEPTTPTTNRPVRERKSVERLVESYDRDASKEFQIEEGRGTPLKNIPNVAFKL------S 432
PT + ++K ++ + + KE + + T +K + KL
Sbjct: 300 ETPTAAEDDNEGDKKKKDKKKKKGEKEEKEKEKKKGPSKAT-VKAMQEALAKLKEEEERQ 358
Query: 433 RRKVDDTLKFLHTILFCRRGKAAVIKKNILRFSGFVWHENEEKQMIKVKEKFDKCNKEKL 492
+R+ ++ +K L + R+ + + E E+++ K KEK KE+L
Sbjct: 359 KREEEERIKRLEELEAKRKEEERL--------------EQEKRERKKQKEKE---RKERL 401
Query: 493 LEFSDLLDVPVGNANTRKEDIIAKLIDFLVAPQVTKSVLLAEQE--KSAKEKRIAKQGST 550
+ LL A R E + KL+ +K L ++ + K K+I +Q +
Sbjct: 402 KKEGKLLTKSQREARARAEATL-KLLQAQGVEVPSKDSLPKKRPIYEDKKRKKIPQQLES 460
Query: 551 GSGTPTSRRSAKSRKKIEDSSIAEKKKTATDTESESEKDEENKEENEIDVSDKSEDEKPI 610
+ + A ++ + + EK++T E E E+D E+ ++ + E+ + +
Sbjct: 461 KEVSESMELCA--AVEVMEQGVPEKEETPPPVEPEEEEDTEDAGLDDWEAMASDEETEKV 518
Query: 611 KG 612
+G
Sbjct: 519 EG 520
Score = 44.3 bits (103), Expect = 0.001
Identities = 81/391 (20%), Positives = 160/391 (40%), Gaps = 55/391 (14%)
Query: 287 KSQKDREDD--KDKVDNKSNEENIKVEKRLKKRGKGKVNGENVKKKMKELKKIEDI-PEA 343
K QK++ +D KD +D + I+ K++ K G+ K+K K+ +DI E
Sbjct: 3 KKQKNKSEDSTKDDIDLDALAAEIEGAGAAKEQEPQKSKGKKKKEKKKQDFDEDDILKEL 62
Query: 344 KDESIEKERSRDEEVGDKEKVGGENVKKKMKELKEAEPTTPTTNRPVRERKSVERLVESY 403
++ S+E + K E V K E E E T+ +++K + +S+
Sbjct: 63 EELSLEAQGI---------KADRETVAVKPTENNEEEFTSKD-----KKKKGQKGKKQSF 108
Query: 404 DRDASKEFQIEEGRGTPLKNIPNVAFKLSRRKVDDTLKFLHTILFCRRGKAAVIKKNILR 463
D + S+E + ++ + P V DD K +GKA +K+ +
Sbjct: 109 DDNDSEELEDKDSKSKKTAK-PKVEMYSGSDDDDDFNKLPKK----AKGKA---QKSNKK 160
Query: 464 FSGFVWHENEEKQMIKVKEK------------FDKCNKEKLLEFSDLLDVPVGNANTRKE 511
+ G E +E K+KE+ D+ + + + + + P N + E
Sbjct: 161 WDG---SEEDEDNSKKIKERSRINSSGESGDESDEFLQSRKGQKKNQKNKPGPNIESGNE 217
Query: 512 DIIAKLIDFLVAPQVTKSVLLAEQEK------SAKEKRIAKQGSTGSGTPTSRRSAKSRK 565
D A F + K E+E+ AK +++ ++ +G + +S++
Sbjct: 218 DDDA---SFKIKTVAQKKAEKKERERKKRDEEKAKLRKLKEKEELETGKKDQSKQKESQR 274
Query: 566 KIEDSSIAEKKKTATDT----ESESEKDEENKEENEIDVSDKSEDEKPIKGKKHIAKQGS 621
K E+ ++ K K DT SE + + E++ + K +D+K KG+K ++
Sbjct: 275 KFEEETV--KSKVTVDTGVIPASEEKAETPTAAEDDNEGDKKKKDKKKKKGEKEEKEKEK 332
Query: 622 SRSGTASSRRSAKE*NIFQKERIRCTKQSKE 652
+ + ++ ++ +E KE K+ +E
Sbjct: 333 KKGPSKATVKAMQEALAKLKEEEERQKREEE 363
>NFM_RAT (P12839) Neurofilament triplet M protein (160 kDa
neurofilament protein) (Neurofilament medium
polypeptide) (NF-M)
Length = 845
Score = 97.4 bits (241), Expect = 1e-19
Identities = 101/382 (26%), Positives = 174/382 (45%), Gaps = 66/382 (17%)
Query: 21 KIFEDNAVQDLK---EDGIKAMEVDKKADGEEVLEMDKLADDGDVVTENAIKAGDGEGIK 77
+I E+ V+D K ED + + + A +E E + ++ V ++ +K+ + + +
Sbjct: 454 EIIEETKVEDEKSEMEDALTVIAEELAASAKEEKEEAEEKEEEPEVEKSPVKSPEAKEEE 513
Query: 78 EDEKVNEGKEIKEDKQADEGEELKEDKKDNGGEERKEDKKVDVGQ--------------- 122
E EK E + +E+++ DEG +K D+ + GG E++ + D G+
Sbjct: 514 EGEKEEEEEGQEEEEEEDEG--VKSDQAEEGGSEKEGSSEKDEGEQEEEGETEAEGEGEE 571
Query: 123 -EVKEDKKVN---EGGDIKEEKKADEGEKLK--------EDKKDDAAVKI-----KEDKK 165
E KE+KK E IKEE K ++ EK K E+ K K KE++K
Sbjct: 572 AEAKEEKKTEGKVEEMAIKEEIKVEKPEKAKSPVPKSPVEEVKPKPEAKAGKDEQKEEEK 631
Query: 166 VNEGEEL-----KEEKKADEGEKLKE--DKKD----------DAGVEIIEDKKVNEGEEL 208
V E +E+ KEEK + EK K+ DKK + + I + KV+ ++
Sbjct: 632 VEEKKEVAKESPKEEKVEKKEEKPKDVPDKKKAESPVKEKAVEEMITITKSVKVSLEKDT 691
Query: 209 EEEKKAEGEELKEDKKVDAG--DEIEEDKKDDNGFEDDKLSEETELSKEERESVEAKKPE 266
+EEK + E++KE + + G +E+ + ++ ED ++ E E KEE E +K
Sbjct: 692 KEEKPQQQEKVKEKAEEEGGSEEEVGDKSPQESKKEDIAINGEVE-GKEEEEQETQEKGS 750
Query: 267 LDAMDEESILEGKDEGSEKEKSQKDREDDKDKVDNKSNEENIKVEKRLKKRGKGKVNGEN 326
++ + G D +EK +DR DDK V KVEK + G G +
Sbjct: 751 GQEEEKGVVTNGLDVSPAEEKKGEDRSDDKVVVTK-------KVEKITSEGGDGAT--KY 801
Query: 327 VKKKMKELKKIEDIPEAKDESI 348
+ K + +K+E+ E +E +
Sbjct: 802 ITKSVTVTQKVEEHEETFEEKL 823
Score = 91.7 bits (226), Expect = 7e-18
Identities = 101/385 (26%), Positives = 173/385 (44%), Gaps = 53/385 (13%)
Query: 48 EEVLEMDKLAD------DGDVVTENAIKAGDGEGIKEDEKVNEGKEIK-------EDKQA 94
EE++E K+ D D V + A E +E E+ E E++ E K+
Sbjct: 453 EEIIEETKVEDEKSEMEDALTVIAEELAASAKEEKEEAEEKEEEPEVEKSPVKSPEAKEE 512
Query: 95 DEGEELKEDKKDNGGEERKEDKKV-----DVGQEVKEDKKVNEGGDIKEEKKAD-EGE-- 146
+EGE KE++++ EE +ED+ V + G KE + G+ +EE + + EGE
Sbjct: 513 EEGE--KEEEEEGQEEEEEEDEGVKSDQAEEGGSEKEGSSEKDEGEQEEEGETEAEGEGE 570
Query: 147 --KLKEDKKDDAAVK---IKEDKKVNEGEELKEEKKADEGEKLKEDKKDDAGVEIIEDKK 201
+ KE+KK + V+ IKE+ KV + E+ K E++K + AG + E K+
Sbjct: 571 EAEAKEEKKTEGKVEEMAIKEEIKVEKPEKAKSPVPKSPVEEVKPKPEAKAGKD--EQKE 628
Query: 202 VNEGEELEEEKKAEGEELKEDKKVDAGDEIEEDKKDDNGFEDDKLSEETELSKEERESVE 261
+ EE +E K +E K +KK + ++ + KK ++ ++ + E ++K + S+E
Sbjct: 629 EEKVEEKKEVAKESPKEEKVEKKEEKPKDVPDKKKAESPVKEKAVEEMITITKSVKVSLE 688
Query: 262 AKKPELDAMDEESILEGKDE--GSEKEKSQKDREDDK-------DKVDNKSNEENIKVEK 312
E +E + E +E GSE+E K ++ K +V+ K EE EK
Sbjct: 689 KDTKEEKPQQQEKVKEKAEEEGGSEEEVGDKSPQESKKEDIAINGEVEGKEEEEQETQEK 748
Query: 313 RL-KKRGKGKV-NGENVK------------KKMKELKKIEDIPEAKDESIEKERSRDEEV 358
++ KG V NG +V K+ KK+E I + K ++ V
Sbjct: 749 GSGQEEEKGVVTNGLDVSPAEEKKGEDRSDDKVVVTKKVEKITSEGGDGATKYITKSVTV 808
Query: 359 GDKEKVGGENVKKKMKELKEAEPTT 383
K + E ++K+ K+ E T
Sbjct: 809 TQKVEEHEETFEEKLVSTKKVEKVT 833
Score = 79.3 bits (194), Expect = 4e-14
Identities = 75/266 (28%), Positives = 131/266 (49%), Gaps = 42/266 (15%)
Query: 135 DIKEEKKADEGEKLKEDKKDDAAVKIKEDKKVNEGEELKEEKKADEGEKLKEDKKDDAGV 194
+I EE K ++ ++ + +DA I E+ + EE +E + EK +E + + + V
Sbjct: 454 EIIEETKVED----EKSEMEDALTVIAEELAASAKEEKEEAE-----EKEEEPEVEKSPV 504
Query: 195 EIIEDKKVNEGEELEEEKKAEGEELKEDKKVDAGDEIEEDKKDDNGFEDDKLSEETELSK 254
+ E K+ EGE+ EEE EG+E E+++ D G ++ D+ ++ G E + SE+ E +
Sbjct: 505 KSPEAKEEEEGEKEEEE---EGQE--EEEEEDEG--VKSDQAEEGGSEKEGSSEKDEGEQ 557
Query: 255 EERESVEAKKPELDAMDEESILEGKDEGSEKEKSQKDREDDKDKVDNKSNEENIKVEKRL 314
EE EA EG +E K+ + + KV+ + +E IKVEK
Sbjct: 558 EEEGETEA------------------EGEGEEAEAKEEKKTEGKVEEMAIKEEIKVEK-- 597
Query: 315 KKRGKGKVNGENVKKKMKELKKIEDIPEAKDESIEKERSRDEEVGDKEKVGGENVKKKMK 374
++ K V K ++E+K + KDE E+E+ +++ KE E V+KK +
Sbjct: 598 PEKAKSPVP----KSPVEEVKPKPEAKAGKDEQKEEEKVEEKKEVAKESPKEEKVEKKEE 653
Query: 375 ELKEAEPTTPTTNRPVRERKSVERLV 400
+ K+ P PV+E K+VE ++
Sbjct: 654 KPKDV-PDKKKAESPVKE-KAVEEMI 677
Score = 58.5 bits (140), Expect = 7e-08
Identities = 126/670 (18%), Positives = 256/670 (37%), Gaps = 114/670 (17%)
Query: 6 LDDSSEKKDLEPKGGKIFEDNAVQDLKEDGIKAMEVDKKADGEEVLEMDKLADDGDVVTE 65
LD ++D+ + E+ ++D E I+A+ D + +E+DK
Sbjct: 171 LDSDHLEEDIHRLKERFEEEARLRDDTEAAIRAVRKDIEESSMVKVELDK---------- 220
Query: 66 NAIKAGDGEGIKEDEKVNEGKEIKEDKQADEGEELKEDKKDNGGEERKEDKKVDVGQEVK 125
K +E ++ + + + + L + + + ERK+ K D+ +K
Sbjct: 221 -----------KVQSLQDEVAFLRSNHEEEVADLLAQIQASHITVERKDYLKTDISTALK 269
Query: 126 EDKKVNEGGDIKEEKKADEGEKLKEDKKDDAAVKIKE----------------------- 162
E + E + +A+E K + K +AA + KE
Sbjct: 270 EIRSQLECHSDQNMHQAEEWFKCRYAKLTEAAEQNKEAIRSAKEEIAEYRRQLQSKSIEL 329
Query: 163 ----------DKKVNEGEELKEEKKADEGEKLKEDKKDDAGVEIIEDKKVNEGEELEEEK 212
++++++ EE + + +++ + + G + + + E ++L K
Sbjct: 330 ESVRGTKESLERQLSDIEERHNHDLSSYQDTIQQLENELRGTKWEMARHLREYQDLLNVK 389
Query: 213 KAEGEELKEDKKVDAGDEIEEDKKDDN---GFEDDKLSEETELSKEERESVEAKKPELDA 269
A E+ +K+ G+E + + T SK ++ VEA K ++
Sbjct: 390 MALDIEIAAYRKLLEGEETRFSTFSGSITGPLYTHRQPSVTISSKIQKTKVEAPKLKVQH 449
Query: 270 MDEESILEG---KDEGSEKEKS--------QKDREDDKDKVDNKSNEENIKVEKRLKKRG 318
E I+E +DE SE E + +++K++ + K EE +VEK K
Sbjct: 450 KFVEEIIEETKVEDEKSEMEDALTVIAEELAASAKEEKEEAEEK--EEEPEVEKSPVKSP 507
Query: 319 KGKVNGENVKKKMKELKKIEDIPEAKDESIEKERSRDEEVGDKEKVGGENVKKKMKELKE 378
+ K E K++ +E ++ E E +DE ++ +++ EE G +++ E + + +E E
Sbjct: 508 EAKEEEEGEKEEEEEGQEEE---EEEDEGVKSDQA--EEGGSEKEGSSEKDEGEQEEEGE 562
Query: 379 AEPTTPTTNRPVRERKSVERLVESYDRDASKEFQIEEGRGTPLKNIPNVAFKLSRRKVDD 438
E +E K E VE + + E +P+ P K
Sbjct: 563 TEAEGEGEEAEAKEEKKTEGKVEEMAIKEEIKVEKPEKAKSPVPKSPVEEVKPKPE---- 618
Query: 439 TLKFLHTILFCRRGKAAVIKKNILRFSGFVWHENEEKQMIKVKEKFDKCNKEKLLEFSDL 498
+ GK + EE+++ + KE + KE+ +E +
Sbjct: 619 ----------AKAGKD---------------EQKEEEKVEEKKEVAKESPKEEKVEKKEE 653
Query: 499 LDVPVGNANTRKEDIIAKLIDFLVAPQVTKSVLLAEQEKSAKEKRIAKQGSTGSGTPTSR 558
V + + + K ++ ++ +TKSV ++ EK KE++ +Q +
Sbjct: 654 KPKDVPDKKKAESPVKEKAVEEMIT--ITKSVKVS-LEKDTKEEKPQQQEKV---KEKAE 707
Query: 559 RSAKSRKKIEDSSIAEKKKTATDTESESEKDEENKEENEIDVSDKSEDEKPIKGKKHIA- 617
S +++ D S E KK E E EE ++E + S + E++ + ++
Sbjct: 708 EEGGSEEEVGDKSPQESKKEDIAINGEVEGKEEEEQETQEKGSGQEEEKGVVTNGLDVSP 767
Query: 618 ---KQGSSRS 624
K+G RS
Sbjct: 768 AEEKKGEDRS 777
Score = 57.4 bits (137), Expect = 1e-07
Identities = 64/248 (25%), Positives = 113/248 (44%), Gaps = 40/248 (16%)
Query: 173 KEEKKADEGEKLKEDKKDDAGVEIIEDKKV-NEGEELEEEKKAEGEELK---EDKKVDAG 228
K +K E KLK K EIIE+ KV +E E+E+ EEL +++K +A
Sbjct: 434 KIQKTKVEAPKLKVQHKFVE--EIIEETKVEDEKSEMEDALTVIAEELAASAKEEKEEAE 491
Query: 229 DEIEEDKKDDNGFEDDKLSEETELSKEERESVEAKKPELDAMDEESILEGKDEGSEKE-K 287
++ EE + + + + + EE E KEE E + ++ E D + + ++ GSEKE
Sbjct: 492 EKEEEPEVEKSPVKSPEAKEEEEGEKEEEEEGQEEEEEEDEGVKSD--QAEEGGSEKEGS 549
Query: 288 SQKDREDDKDKVDNKSNEENIKVEKRLKKRGKGKVNGENVKKKMKELKKIEDIPEAKDES 347
S+KD + +++ + ++ E + E + +K+ +GKV +K+++K K PE
Sbjct: 550 SEKDEGEQEEEGETEAEGEGEEAEAKEEKKTEGKVEEMAIKEEIKVEK-----PEKAKSP 604
Query: 348 IEKERSRDEEVGDKEKVGGENVKKKMKELKEAEPTTPTTNRPVRERKSVERLVESYDRDA 407
+ K + + + K G + K++ K V E+K V
Sbjct: 605 VPKSPVEEVKPKPEAKAGKDEQKEEEK---------------VEEKKEV----------- 638
Query: 408 SKEFQIEE 415
+KE EE
Sbjct: 639 AKESPKEE 646
Score = 56.6 bits (135), Expect = 3e-07
Identities = 123/650 (18%), Positives = 250/650 (37%), Gaps = 98/650 (15%)
Query: 29 QDLKEDGIKAMEVDKKADG-------------EEVLEMDKLADDGDVVTENA--IKAGDG 73
+D++E + +E+DKK EEV ++ + E +K
Sbjct: 206 KDIEESSMVKVELDKKVQSLQDEVAFLRSNHEEEVADLLAQIQASHITVERKDYLKTDIS 265
Query: 74 EGIKEDEKVNEGKEIKEDKQADEGEELKEDKKDNGGEERKEDKKVDVGQEVKEDKKVNEG 133
+KE E + QA+E + + K E+ KE + +E+ E ++ +
Sbjct: 266 TALKEIRSQLECHSDQNMHQAEEWFKCRYAKLTEAAEQNKEAIR-SAKEEIAEYRRQLQS 324
Query: 134 GDIKEEKKADEGEKLKEDKKDDAAVKIKEDKKVNEGEELKEEKKADEGEKLKEDKKDDAG 193
I+ E E L ++++++ EE + + +++ + + G
Sbjct: 325 KSIELESVRGTKESL--------------ERQLSDIEERHNHDLSSYQDTIQQLENELRG 370
Query: 194 VEIIEDKKVNEGEELEEEKKAEGEELKEDKKVDAGDEIEEDKKDDN---GFEDDKLSEET 250
+ + + E ++L K A E+ +K+ G+E + + T
Sbjct: 371 TKWEMARHLREYQDLLNVKMALDIEIAAYRKLLEGEETRFSTFSGSITGPLYTHRQPSVT 430
Query: 251 ELSKEERESVEAKKPELDAMDEESILEG---KDEGSEKEKS--------QKDREDDKDKV 299
SK ++ VEA K ++ E I+E +DE SE E + +++K++
Sbjct: 431 ISSKIQKTKVEAPKLKVQHKFVEEIIEETKVEDEKSEMEDALTVIAEELAASAKEEKEEA 490
Query: 300 DNKSNEENIKVEKRLKKRGKGKVNGENVKKKMKELKKIEDIPEAKDESIEKERSRDEEVG 359
+ K EE +VEK K + K E K++ +E ++ E E +DE ++ +++ EE G
Sbjct: 491 EEK--EEEPEVEKSPVKSPEAKEEEEGEKEEEEEGQEEE---EEEDEGVKSDQA--EEGG 543
Query: 360 DKEKVGGENVKKKMKELKEAEPTTPTTNRPVRERKSVERLVESYDRDASKEFQIEEGRGT 419
+++ E + + +E E E +E K E VE + + E +
Sbjct: 544 SEKEGSSEKDEGEQEEEGETEAEGEGEEAEAKEEKKTEGKVEEMAIKEEIKVEKPEKAKS 603
Query: 420 PLKNIPNVAFKLSRRKVDDTLKFLHTILFCRRGKAAVIKKNILRFSGFVWHENEEKQMIK 479
P+ P K + GK + EE+++ +
Sbjct: 604 PVPKSPVEEVKPKPE--------------AKAGKD---------------EQKEEEKVEE 634
Query: 480 VKEKFDKCNKEKLLEFSDLLDVPVGNANTRKEDIIAKLIDFLVAPQVTKSVLLAEQEKSA 539
KE + KE+ +E + V + + + K ++ ++ +TKSV ++ EK
Sbjct: 635 KKEVAKESPKEEKVEKKEEKPKDVPDKKKAESPVKEKAVEEMIT--ITKSVKVS-LEKDT 691
Query: 540 KEKRIAKQGSTGSGTPTSRRSAKSRKKIEDSSIAEKKKTATDTESESEKDEENKEENEID 599
KE++ +Q K ++K E+ +E++ D + K E+ E++
Sbjct: 692 KEEKPQQQ-------------EKVKEKAEEEGGSEEE--VGDKSPQESKKEDIAINGEVE 736
Query: 600 VSDKSEDEKPIKGKKHIAKQGSSRSGTASSRRSAKE*NIFQKERIRCTKQ 649
++ E E KG ++G +G S K+ +++ TK+
Sbjct: 737 GKEEEEQETQEKGSGQEEEKGVVTNGLDVSPAEEKKGEDRSDDKVVVTKK 786
Score = 44.7 bits (104), Expect = 0.001
Identities = 36/130 (27%), Positives = 56/130 (42%), Gaps = 5/130 (3%)
Query: 536 EKSAKEKRIAKQGSTGSGTPTSRRSAKSRKKIEDSSIAEKKKTATDTESESEKDEENKEE 595
EK K K + P A ++ E+ + EKK+ A ES E+ E KEE
Sbjct: 596 EKPEKAKSPVPKSPVEEVKPKPEAKAGKDEQKEEEKVEEKKEVAK--ESPKEEKVEKKEE 653
Query: 596 NEIDVSDKSEDEKPIKGKKHIAKQGSSRSGTASSRRSAKE*NIFQKERIRCTKQSKESNR 655
DV DK + E P+K K ++S S + KE Q+E++ K+ E
Sbjct: 654 KPKDVPDKKKAESPVKEKAVEEMITITKSVKVSLEKDTKEEKPQQQEKV---KEKAEEEG 710
Query: 656 *NKTSLGTKA 665
++ +G K+
Sbjct: 711 GSEEEVGDKS 720
Score = 35.8 bits (81), Expect = 0.46
Identities = 104/520 (20%), Positives = 204/520 (39%), Gaps = 67/520 (12%)
Query: 133 GGDIKEEKKADEGEKLKEDKKDDAAVKIKEDKKVNEGEELKEEKKADEGEKLKEDKKDDA 192
GGD K + ++E E+L + D A I+ KV+ E+ +E +A E L++ + A
Sbjct: 89 GGDYKLSR-SNEKEQL-QGLNDRFAGYIE---KVHYLEQQNKEIEA-EIHALRQKQASHA 142
Query: 193 GVEIIEDKKVNEGEELEEEKKAEGEELKEDKKVDAGDEIEED--KKDDNGFEDDKLSEET 250
+ D+++ E E E +++ D D +EED + + E+ +L ++T
Sbjct: 143 QLGDAYDQEIRELRATLEMVNHEKAQVQLDS-----DHLEEDIHRLKERFEEEARLRDDT 197
Query: 251 ELS-----KEERES----VEAKKPELDAMDEESILEGKDEGSEKE-----KSQKDREDDK 296
E + K+ ES VE K DE + L E + ++ + K
Sbjct: 198 EAAIRAVRKDIEESSMVKVELDKKVQSLQDEVAFLRSNHEEEVADLLAQIQASHITVERK 257
Query: 297 DKVDNKSNEENIKVEKRLKKRGKGKVNGENVKKKMKELKKIEDIPEAKDESIEKERSRDE 356
D + + ++ +L+ ++ K + K + EA +++ E RS E
Sbjct: 258 DYLKTDISTALKEIRSQLECHSDQNMHQAEEWFKCRYAK----LTEAAEQNKEAIRSAKE 313
Query: 357 EVGDKEKVGGENVKKKMKELKEAEPTTPTTNRPVRERKSVERLVESYDRDASKEFQIEEG 416
E+ + + ++ K EL+ T + R + + + S +D ++ + E
Sbjct: 314 EIAEYRR----QLQSKSIELESVRGTKESLERQLSDIEERHNHDLSSYQDTIQQLE-NEL 368
Query: 417 RGTP---------LKNIPNVAFKLS------RRKVDDTLKFLHTILFCRRGKAAVIKKNI 461
RGT +++ NV L R+ ++ T G ++
Sbjct: 369 RGTKWEMARHLREYQDLLNVKMALDIEIAAYRKLLEGEETRFSTFSGSITGPLYTHRQPS 428
Query: 462 LRFSGFVWHENEEKQMIKVKEKFDKCNKEKLLEFSDLLDVPVGNANTRKEDIIAKLIDFL 521
+ S + E +KV+ KF E+++E + V + + ED + + + L
Sbjct: 429 VTISSKIQKTKVEAPKLKVQHKF----VEEIIE-----ETKVEDEKSEMEDALTVIAEEL 479
Query: 522 VAPQVTKSVLLAEQE------KSAKEKRIAKQGSTGSGTPTSRRSAKSRKKIEDSSIAEK 575
A + E+E KS + AK+ G + ++ E +
Sbjct: 480 AASAKEEKEEAEEKEEEPEVEKSPVKSPEAKEEEEGEKEEEEEGQEEEEEEDEGVKSDQA 539
Query: 576 KKTATDTESESEKDE-ENKEENEIDVSDKSEDEKPIKGKK 614
++ ++ E SEKDE E +EE E + + E+ + + KK
Sbjct: 540 EEGGSEKEGSSEKDEGEQEEEGETEAEGEGEEAEAKEEKK 579
Score = 32.3 bits (72), Expect = 5.1
Identities = 99/477 (20%), Positives = 180/477 (36%), Gaps = 74/477 (15%)
Query: 200 KKVNEGEELEEEKKAEGEELKEDKKVDA--GDEIEEDKKDDNGFEDDKLSEETELSKEER 257
+KV+ E+ +E +AE L++ + A GD +++ ++ L E+ E+
Sbjct: 115 EKVHYLEQQNKEIEAEIHALRQKQASHAQLGDAYDQEIRE--------LRATLEMVNHEK 166
Query: 258 ESVEAKKPELDAMDEESILEGKDEGSEKEKSQKDREDDKDKVDNKSNEENIKVEKRLKKR 317
V+ LD+ E + E E+E +D + + K EE+ V+ L K+
Sbjct: 167 AQVQ-----LDSDHLEEDIHRLKERFEEEARLRDDTEAAIRAVRKDIEESSMVKVELDKK 221
Query: 318 GKG---------KVNGENVKKKMKELKKIEDIPEAKD-------ESIEKERSRDEEVGDK 361
+ + E V + +++ E KD ++++ RS+ E D+
Sbjct: 222 VQSLQDEVAFLRSNHEEEVADLLAQIQASHITVERKDYLKTDISTALKEIRSQLECHSDQ 281
Query: 362 EKVGGEN-VKKKMKELKEAEPTTPTTNRPVRERKSVERLVESYDRDA-SKEFQIEEGRGT 419
E K + +L EA R +E + Y R SK ++E RGT
Sbjct: 282 NMHQAEEWFKCRYAKLTEAAEQNKEAIRSAKEE------IAEYRRQLQSKSIELESVRGT 335
Query: 420 PLKNIPNVAFKLSRRKVDDTLKFLHTILFCRRGKAAVIKKNILRFSGFVW----HENEEK 475
+++ + R D + TI +N LR G W H E +
Sbjct: 336 K-ESLERQLSDIEERHNHDLSSYQDTIQQL---------ENELR--GTKWEMARHLREYQ 383
Query: 476 QMIKVKEKFDK--CNKEKLLE--------FSDLLDVPVGNANTRKEDIIAKLIDFLV-AP 524
++ VK D KLLE FS + P+ I +K+ V AP
Sbjct: 384 DLLNVKMALDIEIAAYRKLLEGEETRFSTFSGSITGPLYTHRQPSVTISSKIQKTKVEAP 443
Query: 525 QVTKSVLLAEQEKSAKEKRIAKQGSTGSGTPTSRRSAKSRKKIEDSSIAEKKKTATDTES 584
++ E+ + K + T + A S K E+ AE+K+ + E
Sbjct: 444 KLKVQHKFVEEIIEETKVEDEKSEMEDALTVIAEELAASAK--EEKEEAEEKEEEPEVEK 501
Query: 585 ------ESEKDEENKEENEIDVSDKSEDEKPIKGKKHIAKQGSSRSGTASSRRSAKE 635
E++++EE ++E E + ++ E+E + GS + G++ +E
Sbjct: 502 SPVKSPEAKEEEEGEKEEEEEGQEEEEEEDEGVKSDQAEEGGSEKEGSSEKDEGEQE 558
>ATRX_CAEEL (Q9U7E0) Transcriptional regulator ATRX homolog
(X-linked nuclear protein-1)
Length = 1359
Score = 95.9 bits (237), Expect = 4e-19
Identities = 87/377 (23%), Positives = 175/377 (46%), Gaps = 42/377 (11%)
Query: 72 DGEG-IKEDEKVNEGKEIKEDKQADEGEELKEDKKDNGGEERKE----DKKVDVGQEVKE 126
D +G + EDE + ++I+ +++ ++LKE ++ G K+ +K +E +
Sbjct: 10 DSDGHVIEDEDLEMARQIENERKEKRAQKLKEKREREGKPPPKKRPAKKRKASSSEEDDD 69
Query: 127 DKKVNEGGDIKEEKKA--DEGEKLKEDKKDDAAVKIKEDKKVNEGEELKEEKKA------ 178
D++ + K+ +K E E + D+++D K K KKV++ ++ K +KK
Sbjct: 70 DEEESPRKSSKKSRKRAKSESESDESDEEEDRK-KSKSKKKVDQKKKEKSKKKRTTSSSE 128
Query: 179 -DEGEKLKEDKKDDAGVEIIEDKKVNEGEELEEEKKAEGEELKEDKKV----DAGDEIEE 233
++ ++ +E K + + EE EEE+K + + ++K V + +E +E
Sbjct: 129 DEDSDEEREQKSKKKSKKTKKQTSSESSEESEEERKVKKSKKNKEKSVKKRAETSEESDE 188
Query: 234 D----KKDDNGFEDDKLSEETELSKEERESVEAKKPELDAMDEESILEGKDEGSEKEKSQ 289
D KK G + SE S++E+E ++KK + +ES E +DE EK+K++
Sbjct: 189 DEKPSKKSKKGLKKKAKSESESESEDEKEVKKSKKKSKKVVKKES--ESEDEAPEKKKTE 246
Query: 290 KDREDDKDKVDNKSNEENIKVEKRLKKRGKGKVNGENVKKKM-----KELKKIEDIPEAK 344
K + ++ +E++ + E+ + K K KK+ E +E +P+ K
Sbjct: 247 KRKRSKTSSEESSESEKSDEEEEEKESSPKPKKKKPLAVKKLSSDEESEESDVEVLPQKK 306
Query: 345 ---------DESIEKERSRDEEVGD-KEKVGGENVKKK--MKELKEAEPTTPTTNRPVRE 392
D EK++ + E D +EKV + KK+ + ++ + T NR ++
Sbjct: 307 KRGAVTLISDSEDEKDQKSESEASDVEEKVSKKKAKKQESSESGSDSSEGSITVNRKSKK 366
Query: 393 RKSVERLVESYDRDASK 409
++ E+ + D+SK
Sbjct: 367 KEKPEKKKKGIIMDSSK 383
Score = 93.2 bits (230), Expect = 2e-18
Identities = 125/525 (23%), Positives = 226/525 (42%), Gaps = 79/525 (15%)
Query: 7 DDSSEKKDLEPKGGKIFEDNAVQDLKEDGIKAMEVDKKADGEEVLEMDKLADDGDVVTEN 66
D+S E++D + K D Q KE K D + E ++ + T+
Sbjct: 93 DESDEEEDRKKSKSKKKVD---QKKKEKSKKKRTTSSSEDEDSDEEREQKSKKKSKKTKK 149
Query: 67 AIKAGDGEGIKEDEKVNEGKEIKE---DKQADEGEELKEDKKDNGGEER--KEDKKVDVG 121
+ E +E+ KV + K+ KE K+A+ EE ED+K + ++ K+ K +
Sbjct: 150 QTSSESSEESEEERKVKKSKKNKEKSVKKRAETSEESDEDEKPSKKSKKGLKKKAKSESE 209
Query: 122 QEVKEDKKVNEGGDIKEEKKADEGEKLKEDKKDDAAVKIKEDKK---VNEGEELKEEKKA 178
E +++K+V K +KK+ + K + + +D+A K K +K+ EE E +K+
Sbjct: 210 SESEDEKEVK-----KSKKKSKKVVKKESESEDEAPEKKKTEKRKRSKTSSEESSESEKS 264
Query: 179 DEGEKLKEDKKDDAGVEIIEDKKVNEGEELEEEKKAEGEELKEDKKVDAGDEI--EEDKK 236
DE E+ KE + + KK++ EE EE ++ E L + KK A I ED+K
Sbjct: 265 DEEEEEKESSPKPKKKKPLAVKKLSSDEESEE---SDVEVLPQKKKRGAVTLISDSEDEK 321
Query: 237 DDNGFEDDKLSEETELSKEERESVEAKKPELDAMDEESILEGKDEGSEK-EKSQKDREDD 295
D E + E ++SK++ + E+ + D+ + + K + EK EK +K D
Sbjct: 322 DQKS-ESEASDVEEKVSKKKAKKQESSESGSDSSEGSITVNRKSKKKEKPEKKKKGIIMD 380
Query: 296 KDKVDNKSNEENIKVEKRLKKRGKGKVNGENVKKKMKELKKIEDIPEAKDESIEKERSRD 355
K+ +E I E+ K+R K ++KK KE I + E +D +
Sbjct: 381 SSKL----QKETIDAERAEKERRK------RLEKKQKEFNGIV-LEEGEDLT-------- 421
Query: 356 EEVGDKEKVGGENVKKKMKEL---KEAEPTTPTTNRPVRERKSVERLVE---------SY 403
E + G + ++K+K + ++ + +PV S+ R+++ Y
Sbjct: 422 ------EMLTGTSSQRKLKSVVLDPDSSTVDEESKKPVEVHNSLVRILKPHQAHGIQFMY 475
Query: 404 DRDASKEFQIE-EGRGTPLKNIPNVAFKLSRRKVDDTLKFLHTILF-------CRRGKAA 455
D +++ EG G L A + K + FLHT+L C+R
Sbjct: 476 DCACESLDRLDTEGSGGIL------AHCMGLGKTLQVITFLHTVLMHEKIGEKCKR-VLV 528
Query: 456 VIKKNILRFSGFVWHENEEKQMIKVKEKFDKCNKEKLLEFSDLLD 500
V+ KN++ W + +K ++ E+ D + +L + + D
Sbjct: 529 VVPKNVI----INWFKEFQKWLVDNDEELDTIDVNELDSYKTIED 569
Score = 89.0 bits (219), Expect = 5e-17
Identities = 104/464 (22%), Positives = 200/464 (42%), Gaps = 32/464 (6%)
Query: 152 KKDDAAVKIKEDKKVNEGEELKEEKKADEGEKLKEDK----KDDAGVEIIEDKKVNEGEE 207
+ +D+ + ED+ + +++ E+K +KLKE + K + +K + EE
Sbjct: 7 ESEDSDGHVIEDEDLEMARQIENERKEKRAQKLKEKREREGKPPPKKRPAKKRKASSSEE 66
Query: 208 LEEEKKAEGEELKEDKKVDAGDEIEEDKKDDNGFEDDKLSEETELSKEERESVEAKKPEL 267
+++++ + + + A E E D+ D+ E+D+ +++ ++++ ++KK
Sbjct: 67 DDDDEEESPRKSSKKSRKRAKSESESDESDE---EEDRKKSKSKKKVDQKKKEKSKKKRT 123
Query: 268 DAMDEESILEGKDEGSEKEKSQKDREDDKDKVDNKSNEENIKV-------EKRLKKRGKG 320
+ E+ + + E K+KS+K ++ + +S EE KV EK +KKR +
Sbjct: 124 TSSSEDEDSDEEREQKSKKKSKKTKKQTSSESSEESEEER-KVKKSKKNKEKSVKKRAET 182
Query: 321 KVNGENVKKKMKELKKIEDIPEAKDESIEKERSRDEEVGDKEKVGGENVKKKMKELKEAE 380
+ +K K+ KK +AK ES + S DE+ K K + V KK E ++
Sbjct: 183 SEESDEDEKPSKKSKKGLK-KKAKSES--ESESEDEKEVKKSKKKSKKVVKKESESEDEA 239
Query: 381 PTTPTTNRPVRERKSVERLVESYDRDASKEFQIEEGRGTPLKNIPNVAFKLSRRKVDDTL 440
P T + R + S E ES D +E + +E P K P KLS + +
Sbjct: 240 PEKKKTEKRKRSKTSSEESSESEKSD--EEEEEKESSPKPKKKKPLAVKKLSSDEESEES 297
Query: 441 KFLHTILFCRRGKAAVIKKNILRFSGFVWHENEEKQMIKVKEKFDKCNKEKLLEFSDLLD 500
+L ++ + AV ++ S + E + V+EK K +K D
Sbjct: 298 DV--EVLPQKKKRGAV---TLISDSEDEKDQKSESEASDVEEKVSKKKAKKQESSESGSD 352
Query: 501 VPVG----NANTRKEDIIAKLIDFLV--APQVTKSVLLAEQEKSAKEKRIAKQGSTGSGT 554
G N ++K++ K ++ + ++ K + AE+ + + KR+ K+ +G
Sbjct: 353 SSEGSITVNRKSKKKEKPEKKKKGIIMDSSKLQKETIDAERAEKERRKRLEKKQKEFNGI 412
Query: 555 PTSRRSAKSRKKIEDSSIAEKKKTATDTESESEKDEENKEENEI 598
+ SS + K D +S S DEE+K+ E+
Sbjct: 413 VLEEGEDLTEMLTGTSSQRKLKSVVLDPDS-STVDEESKKPVEV 455
Score = 82.4 bits (202), Expect = 4e-15
Identities = 98/452 (21%), Positives = 195/452 (42%), Gaps = 39/452 (8%)
Query: 75 GIKEDEKVNEGKEIKEDKQADEGEELKEDKKDNGGEERKEDKKVDVGQEVKEDKKVNEGG 134
G+ E E ++G I ED+ + +++ ++K+ ++ KE ++ +E K K
Sbjct: 4 GVSESED-SDGHVI-EDEDLEMARQIENERKEKRAQKLKEKRE----REGKPPPKKRPA- 56
Query: 135 DIKEEKKADEGEKLKEDKKDDAAVKIKEDKKVNEGEELKEEKKADEGEKLKEDKKDDAGV 194
+++KA E+ +D+++ K+ +K K E ++DE ++ +ED+K
Sbjct: 57 ---KKRKASSSEEDDDDEEESPRKSSKKSRK-----RAKSESESDESDE-EEDRKKSKSK 107
Query: 195 EIIEDKKVNEGEELEEEKKAEGEELKEDKKVDAGDEIEEDKKDDNGFEDDKLSEETELSK 254
+ ++ KK + ++ +E E+ E+++ + + ++ KK + SE +E S+
Sbjct: 108 KKVDQKKKEKSKKKRTTSSSEDEDSDEEREQKSKKKSKKTKKQTS-------SESSEESE 160
Query: 255 EERESVEAKK-PELDAMDEESILEGKDEGSEKEKSQKDREDDKDKVDNKSNEENIKVEKR 313
EER+ ++KK E E DE + K K K K +++S E+ K K+
Sbjct: 161 EERKVKKSKKNKEKSVKKRAETSEESDEDEKPSKKSKKGLKKKAKSESESESEDEKEVKK 220
Query: 314 LKKRGKGKVNGENVKK-KMKELKKIEDIPEAKDESIEKERSRDEEVGDKEKVGGENVKKK 372
KK+ K V E+ + + E KK E +K S E S + ++EK KKK
Sbjct: 221 SKKKSKKVVKKESESEDEAPEKKKTEKRKRSKTSSEESSESEKSDEEEEEKESSPKPKKK 280
Query: 373 ----MKELKEAEPTTPTTNRPVRERKSVERLVESYDRDASKEFQIEEGRGTPLKNIPNVA 428
+K+L E + + + ++K + D + K+ + E + +
Sbjct: 281 KPLAVKKLSSDEESEESDVEVLPQKKKRGAVTLISDSEDEKDQKSESEASDVEEKVSKKK 340
Query: 429 FKLSRRKVDDTLKFLHTILFCRRG----KAAVIKKNILRFSGFVWHEN------EEKQMI 478
K + +I R+ K KK I+ S + E E+++
Sbjct: 341 AKKQESSESGSDSSEGSITVNRKSKKKEKPEKKKKGIIMDSSKLQKETIDAERAEKERRK 400
Query: 479 KVKEKFDKCNKEKLLEFSDLLDVPVGNANTRK 510
++++K + N L E DL ++ G ++ RK
Sbjct: 401 RLEKKQKEFNGIVLEEGEDLTEMLTGTSSQRK 432
Score = 67.0 bits (162), Expect = 2e-10
Identities = 95/444 (21%), Positives = 166/444 (36%), Gaps = 61/444 (13%)
Query: 232 EEDKKDDNGFEDDKLSEETELSKEERESVEAKKPELDAMDEESILEGKDEGSEKEKSQKD 291
E + D + ED+ L ++ E +E K E + E K ++K K+
Sbjct: 7 ESEDSDGHVIEDEDLEMARQIENERKEKRAQKLKE--KREREGKPPPKKRPAKKRKASSS 64
Query: 292 REDDKDKVDNKSNEENIKVEKRLKKRGKGKVNG-----ENVKKKMKELKKIEDIPEAKDE 346
EDD D+ E K K+ +KR K + E +KK K KK++ + K +
Sbjct: 65 EEDDDDE-----EESPRKSSKKSRKRAKSESESDESDEEEDRKKSKSKKKVDQKKKEKSK 119
Query: 347 SIEKERSRDEEVGDKEKVGGENVKKKMKELKEAEPTTPTTNRPVRERKSVERLVESYDRD 406
S ++E D+E+ K K K K + T+ ++ E + V++ ++ ++
Sbjct: 120 KKRTTSSSEDEDSDEER----EQKSKKKSKKTKKQTSSESSEESEEERKVKKSKKNKEKS 175
Query: 407 ASKEFQIEEGRGT---PLKNIPNVAFKLSRRKVDDTLKFLHTILFCRRGKAAVIKKNILR 463
K + E P K K ++ + + + + ++ V+KK
Sbjct: 176 VKKRAETSEESDEDEKPSKKSKKGLKKKAKSESESESEDEKEVKKSKKKSKKVVKK---- 231
Query: 464 FSGFVWHENEEKQMIKVKEKFDKCNKEKLLEFSDLLDVPVGNANTRKEDIIAKLIDFLVA 523
E+E + K+K +K + K KE +
Sbjct: 232 -------ESESEDEAPEKKKTEKRKRSKTSSEESSESEKSDEEEEEKES----------S 274
Query: 524 PQVTKSVLLAEQEKSAKEKRIAKQGSTGSGTPTSRRSAKSR-KKIEDSSIAEKKKTATDT 582
P+ K LA ++ S+ E+ +++ +R A + ED + + A+D
Sbjct: 275 PKPKKKKPLAVKKLSSDEE--SEESDVEVLPQKKKRGAVTLISDSEDEKDQKSESEASDV 332
Query: 583 ESESEKDEENKEENEIDVSDKSE-----------DEKPIKGKKHIAKQGSS-RSGTASSR 630
E + K + K+E+ SD SE EKP K KK I S + T +
Sbjct: 333 EEKVSKKKAKKQESSESGSDSSEGSITVNRKSKKKEKPEKKKKGIIMDSSKLQKETIDAE 392
Query: 631 RSAKE*NIFQKERIRCTKQSKESN 654
R+ KE R R K+ KE N
Sbjct: 393 RAEKE------RRKRLEKKQKEFN 410
Score = 46.6 bits (109), Expect = 3e-04
Identities = 49/262 (18%), Positives = 111/262 (41%), Gaps = 41/262 (15%)
Query: 534 EQEKSAKEKRIAKQGSTGSGTPTSRRSAKSRKKIEDSSIAEKKKTATDTESESEKDEENK 593
E E+ K + K+ G P ++ ++K S + + + +S + + K
Sbjct: 28 ENERKEKRAQKLKEKREREGKPPPKKRPAKKRKASSSEEDDDDEEESPRKSSKKSRKRAK 87
Query: 594 EENEIDVSDKSEDEKPIKGKKHIAKQGSSRSGTASSRRSAKE*NIFQKERIRCTKQSKES 653
E+E D SD+ ED K K KK + ++ +S + S+++ + ++ + K+SK++
Sbjct: 88 SESESDESDEEEDRKKSKSKKKVDQKKKEKSKKKRTTSSSEDEDSDEEREQKSKKKSKKT 147
Query: 654 NR*NKTSLGTKANF*EAIVYTLCI*SW***WKSQGLFKEEEK*KTRKAEDLNSHQVFLQR 713
+ +TS S+ + EE+ K +K++ V
Sbjct: 148 KK--QTS-------------------------SESSEESEEERKVKKSKKNKEKSV---- 176
Query: 714 QSRKIKNKEKSDPSDDQLRKAICVIFKKVDFNTATFADILKLLGKQFDVDLTPRKASVKT 773
++ + E+SD + +K+ + KK + + ++ K + K K K
Sbjct: 177 -KKRAETSEESDEDEKPSKKSKKGLKKKAKSESESESEDEKEVKKS--------KKKSKK 227
Query: 774 IIQQELAKLAEEDEEREQRERR 795
++++E ++ +E E+++ E+R
Sbjct: 228 VVKKE-SESEDEAPEKKKTEKR 248
Score = 45.1 bits (105), Expect = 8e-04
Identities = 52/268 (19%), Positives = 115/268 (42%), Gaps = 40/268 (14%)
Query: 534 EQEKSAKEKRIAKQGSTGSGTPTSRRSAKSRKKIEDSSIAEKKKTATDTESESEKDEENK 593
+ K ++++ ++ S S R+ +KS+KK++ + KK T + SE E +E +
Sbjct: 77 KSSKKSRKRAKSESESDESDEEEDRKKSKSKKKVDQKKKEKSKKKRTTSSSEDEDSDEER 136
Query: 594 EENEIDVSDKSEDEKPIKGKKHIAKQGSSRSGTASSRRSAKE*NIFQKERIRCTKQSKES 653
E+ S K++ + + + ++ + + +S K+ +E K SK+S
Sbjct: 137 EQKSKKKSKKTKKQTSSESSEESEEERKVKKSKKNKEKSVKKRAETSEESDEDEKPSKKS 196
Query: 654 NR*NKTSLGTKANF*EAIVYTLCI*SW***WKSQGLFKEEEK*KTRKAEDLNSHQVFLQR 713
K L KA KS+ + E++ + +K+ ++
Sbjct: 197 ----KKGLKKKA-------------------KSESESESEDEKEVKKS----------KK 223
Query: 714 QSRKIKNKEKSDPSDDQLRKAICVIFKKVDFNTATFADILKLLGKQFDVDLTPRKASVKT 773
+S+K+ KE S+ D+ K K+ ++ ++ K ++ + + +P+ K
Sbjct: 224 KSKKVVKKE-SESEDEAPEKKKTEKRKRSKTSSEESSESEKSDEEEEEKESSPKPKKKKP 282
Query: 774 IIQQELAKLAEEDEERE-----QRERRG 796
+ ++L+ EE EE + Q+++RG
Sbjct: 283 LAVKKLSS-DEESEESDVEVLPQKKKRG 309
>NFM_RABIT (P54938) Neurofilament triplet M protein (160 kDa
neurofilament protein) (Neurofilament medium
polypeptide) (NF-M) (Fragment)
Length = 644
Score = 95.5 bits (236), Expect = 5e-19
Identities = 106/395 (26%), Positives = 186/395 (46%), Gaps = 76/395 (19%)
Query: 11 EKKDLEPKGGKIFEDNAVQDLKEDGIKAMEVDKKADGEEVLEMDKLADDGDVVTENAIKA 70
EK ++E I E+ AV +K E +++A+G+E E + ++ ++ +KA
Sbjct: 251 EKSEMEDALTAIAEELAVS------VKEEEKEEEAEGKE--EEQEAEEEVAAAKKSPVKA 302
Query: 71 GDGEGIKEDEKVNEGKEIKEDKQADEGEELKEDKKDNGGEERKEDKKVDVGQEVKEDKKV 130
E IKE+E E +E +E+++ +E E +K D+ + GG E++ K + QE E +
Sbjct: 303 TTPE-IKEEEGEKE-EEGQEEEEEEEDEGVKSDQAEEGGSEKEGSSKNEGEQEEGETEAE 360
Query: 131 NE--GGDIKEEKKADEGEKLKEDKKDDAAVKIK--EDKKVNEGEELKEEKKADEGEKLKE 186
E + KEEKK E+K ++ A K + + KV + E+ K E++K
Sbjct: 361 GEVEEAEAKEEKKT-------EEKSEEVAAKEEPVTEAKVGKPEKAKSPVPKSPVEEVKP 413
Query: 187 DKKDDAGVEIIEDKKVNEGEELEEEKKAEGEELKEDKKVDAGDEIEED---KKDDNGFED 243
+ AG + ++ E E++EEEKK +E +++KV+ +E +D KK ++ ++
Sbjct: 414 KAEATAG----KGEQKEEEEKVEEEKKKAAKESPKEEKVEKKEEKPKDVPKKKAESPVKE 469
Query: 244 DKLSEETELSKE-----ERESVEAKKPELDAMDEESILEGKDEGSEKEKSQKDREDDKDK 298
+ E ++K E+E+ E +KP ++E G++ GSE+E S D+
Sbjct: 470 EAAEEAATITKPTKVGLEKETKEGEKPLQQEKEKEK--AGEEGGSEEEGS--------DQ 519
Query: 299 VDNKSNEENIKVEKRLKKRGKGKVNGENVKKKMKELKKIEDIPEAKDESIEKERSRDEEV 358
++ +E+I VNGE K+ E+ PE K EK R+EE
Sbjct: 520 GSKRAKKEDI------------AVNGEGEGKE-------EEEPETK----EKGSGREEEK 556
Query: 359 G----------DKEKVGGENVKKKMKELKEAEPTT 383
G EK GG+ ++K+ K+ E T
Sbjct: 557 GVVTNGLDLSPADEKKGGDRSEEKVVVTKKVEKIT 591
Score = 92.8 bits (229), Expect = 3e-18
Identities = 93/317 (29%), Positives = 146/317 (45%), Gaps = 61/317 (19%)
Query: 98 EELKEDKKDNGGEERKEDKKVDVGQE----VKEDKKVNEGGDIKEEKKADE---GEKLKE 150
EE+ E+ K + ED + +E VKE++K E +EE++A+E K
Sbjct: 240 EEIIEETKVEDEKSEMEDALTAIAEELAVSVKEEEKEEEAEGKEEEQEAEEEVAAAKKSP 299
Query: 151 DKKDDAAVKIKEDKKVNEGEELKEEKKADEGEKLKEDKKDDAGVEIIEDKKVNEGEELEE 210
K +K +E +K EG+E +EE++ DEG +K D+ ++ G E E NEGE+ E
Sbjct: 300 VKATTPEIKEEEGEKEEEGQE-EEEEEEDEG--VKSDQAEEGGSEK-EGSSKNEGEQEEG 355
Query: 211 EKKAEGE----ELKEDKKVDAGDEIEEDKKDDNGFEDDKLSEETELSKEERESVEAKKPE 266
E +AEGE E KE+KK E+K ++ +++ ++E E+ +S K P
Sbjct: 356 ETEAEGEVEEAEAKEEKKT-------EEKSEEVAAKEEPVTEAKVGKPEKAKSPVPKSPV 408
Query: 267 LDAMDEESILEGKDEGSEKEKSQKDREDDKDKVDNKSNEENIKVEKRLKKRGKGKVNGEN 326
+ + GK E E+E+ KVE+ KK K E
Sbjct: 409 EEVKPKAEATAGKGEQKEEEE---------------------KVEEEKKKAAKESPKEEK 447
Query: 327 VKKKMKELKKIEDIPEAKDESIEKERSRDE--EVGDKEKVGGENVKKKMKELKEAEPTTP 384
V+KK +K +D+P+ K ES KE + +E + KVG E KE KE E
Sbjct: 448 VEKKE---EKPKDVPKKKAESPVKEEAAEEAATITKPTKVGLE------KETKEGE---- 494
Query: 385 TTNRPVRERKSVERLVE 401
+P+++ K E+ E
Sbjct: 495 ---KPLQQEKEKEKAGE 508
Score = 78.6 bits (192), Expect = 6e-14
Identities = 87/297 (29%), Positives = 131/297 (43%), Gaps = 42/297 (14%)
Query: 135 DIKEEKKADEGEKLKEDK----KDDAAVKIKEDKKVNEGEELKEEKKADE---GEKLKED 187
+I EE K ++ + ED ++ AV +KE++K E E +EE++A+E K
Sbjct: 241 EIIEETKVEDEKSEMEDALTAIAEELAVSVKEEEKEEEAEGKEEEQEAEEEVAAAKKSPV 300
Query: 188 KKDDAGVEIIEDKKVNEGEELEEEKKAEGEELKEDKKVDAGDEIEEDKKDDNGFEDDKLS 247
K ++ E +K EG+E EEE++ EG +K D+ + G E E K++ E+ +
Sbjct: 301 KATTPEIKEEEGEKEEEGQEEEEEEEDEG--VKSDQAEEGGSEKEGSSKNEGEQEEGETE 358
Query: 248 EETELSKEERESVEAKKPELD----AMDEESILEGKDEGSEKEKSQKDREDDKDKVDNKS 303
E E+ EE E+ E KK E A EE + E K EK KS KS
Sbjct: 359 AEGEV--EEAEAKEEKKTEEKSEEVAAKEEPVTEAKVGKPEKAKSPVP----------KS 406
Query: 304 NEENIKVEKRLKKRGKGKVNGENVKKKMKELKKIEDIPEAKDESIEKERSRDEEVGDKEK 363
E +K K GKG E K+ E+ E + + KE ++E+V KE+
Sbjct: 407 PVEEVK-PKAEATAGKG------------EQKEEEEKVEEEKKKAAKESPKEEKVEKKEE 453
Query: 364 VGGENVKKK----MKELKEAEPTTPTTNRPVRERKSVERLVESYDRDASKEFQIEEG 416
+ KKK +KE E T T V K + + ++ KE EEG
Sbjct: 454 KPKDVPKKKAESPVKEEAAEEAATITKPTKVGLEKETKEGEKPLQQEKEKEKAGEEG 510
Score = 68.6 bits (166), Expect = 6e-11
Identities = 64/256 (25%), Positives = 123/256 (48%), Gaps = 20/256 (7%)
Query: 173 KEEKKADEGEKLKEDKKDDAGVEIIEDKKV-NEGEELEEEKKAEGEELKEDKKVDAGDEI 231
K +K E KLK K EIIE+ KV +E E+E+ A EEL K
Sbjct: 221 KIQKTKVEAPKLKVQHKFVE--EIIEETKVEDEKSEMEDALTAIAEELAVSVK------- 271
Query: 232 EEDKKDDNGFEDDKLSEETELSKEERESVEAKKPELDAMDEESILEGKDEGSEKEKSQKD 291
EE+K+++ ++++ E E++ ++ V+A PE+ + E K+E ++E+ +++
Sbjct: 272 EEEKEEEAEGKEEEQEAEEEVAAAKKSPVKATTPEIKEEEGE-----KEEEGQEEEEEEE 326
Query: 292 REDDK--DKVDNKSNEENIKVEKRLKKRGKGKVNGENVKKKMKELKKIEDIPEAKDESIE 349
E K + S +E + ++ G+ + GE + + KE KK E+ ++++ + +
Sbjct: 327 DEGVKSDQAEEGGSEKEGSSKNEGEQEEGETEAEGEVEEAEAKEEKKTEE--KSEEVAAK 384
Query: 350 KERSRDEEVGDKEKVGGENVKKKMKELKEAEPTTPTTNRPVRERKSVERLVESYDRDASK 409
+E + +VG EK K ++E+K T E + VE + +++ K
Sbjct: 385 EEPVTEAKVGKPEKAKSPVPKSPVEEVKPKAEATAGKGEQKEEEEKVEEEKKKAAKESPK 444
Query: 410 EFQIEEGRGTPLKNIP 425
E ++E+ P K++P
Sbjct: 445 EEKVEKKEEKP-KDVP 459
Score = 36.6 bits (83), Expect = 0.27
Identities = 29/94 (30%), Positives = 42/94 (43%), Gaps = 12/94 (12%)
Query: 528 KSVLLAEQEKSAKEKRIAKQGSTGSGTPTS----------RRSAKSRKKIEDSSIAEKKK 577
KS +A +E+ E ++ K S P S + K +K E+ + E+KK
Sbjct: 377 KSEEVAAKEEPVTEAKVGKPEKAKSPVPKSPVEEVKPKAEATAGKGEQKEEEEKVEEEKK 436
Query: 578 TATDTESESEKDEENKEENEIDVSDKSEDEKPIK 611
A ES E+ E KEE DV K + E P+K
Sbjct: 437 KAA-KESPKEEKVEKKEEKPKDV-PKKKAESPVK 468
Score = 33.1 bits (74), Expect = 3.0
Identities = 26/123 (21%), Positives = 56/123 (45%), Gaps = 8/123 (6%)
Query: 535 QEKSAKEKRIAKQGSTGSGTPTSRRSAKSRKKIEDSSIAEKKKTATDTESESEKDEENKE 594
+E +AKE+ + + G P +S + +E+ + K AT + E +++EE E
Sbjct: 379 EEVAAKEEPVTE---AKVGKPEKAKSPVPKSPVEE---VKPKAEATAGKGEQKEEEEKVE 432
Query: 595 ENEIDVSDKSEDEKPIKGKKHIAKQGSSRSGTASSRRSAKE--*NIFQKERIRCTKQSKE 652
E + + +S E+ ++ K+ K + + + A E I + ++ K++KE
Sbjct: 433 EEKKKAAKESPKEEKVEKKEEKPKDVPKKKAESPVKEEAAEEAATITKPTKVGLEKETKE 492
Query: 653 SNR 655
+
Sbjct: 493 GEK 495
Score = 32.3 bits (72), Expect = 5.1
Identities = 26/128 (20%), Positives = 55/128 (42%), Gaps = 20/128 (15%)
Query: 508 TRKEDIIAKLIDFLVAPQVTKSVLLAEQEKSAKEKRIAKQGSTGSGTPTSRRSAKSRKKI 567
T+ ED +++ D L A +V + E+EK + + K ++
Sbjct: 246 TKVEDEKSEMEDALTAIAEELAVSVKEEEKEEEAE------------------GKEEEQE 287
Query: 568 EDSSIAEKKKTATDTESESEKDEENKEENEIDVSDKSEDEKPIKGKKHIAKQGSSRSGTA 627
+ +A KK+ + K+EE ++E E ++ E+++ +K + A++G S +
Sbjct: 288 AEEEVAAAKKSPVKATTPEIKEEEGEKEEEGQEEEEEEEDEGVKSDQ--AEEGGSEKEGS 345
Query: 628 SSRRSAKE 635
S +E
Sbjct: 346 SKNEGEQE 353
Score = 32.0 bits (71), Expect = 6.6
Identities = 24/113 (21%), Positives = 53/113 (46%), Gaps = 3/113 (2%)
Query: 533 AEQEKSAKEKRIAKQGSTGSGTPTSRRSAKSRKKIEDSS--IAEKKKTATDTE-SESEKD 589
+E+E S+K + ++G T + AK KK E+ S +A K++ T+ + + EK
Sbjct: 340 SEKEGSSKNEGEQEEGETEAEGEVEEAEAKEEKKTEEKSEEVAAKEEPVTEAKVGKPEKA 399
Query: 590 EENKEENEIDVSDKSEDEKPIKGKKHIAKQGSSRSGTASSRRSAKE*NIFQKE 642
+ ++ ++ + KG++ ++ +++ S KE + +KE
Sbjct: 400 KSPVPKSPVEEVKPKAEATAGKGEQKEEEEKVEEEKKKAAKESPKEEKVEKKE 452
Score = 32.0 bits (71), Expect = 6.6
Identities = 25/120 (20%), Positives = 53/120 (43%), Gaps = 4/120 (3%)
Query: 539 AKEKRIAKQGSTGSGTPTSRRSAKSRKKIEDSSIAEKKKTATDTESESEKDEENKEENEI 598
A+E K+GS+ + ++ ++E++ E+KKT +E + K EE E ++
Sbjct: 335 AEEGGSEKEGSSKNEGEQEEGETEAEGEVEEAEAKEEKKTEEKSEEVAAK-EEPVTEAKV 393
Query: 599 DVSDKSEDEKPIKGKKHIAKQGSSRSGTASSRRSAKE*NIFQKERIRCTKQSKESNR*NK 658
+K++ P K + + TA +E ++E+ + K+S + + K
Sbjct: 394 GKPEKAKSPVP---KSPVEEVKPKAEATAGKGEQKEEEEKVEEEKKKAAKESPKEEKVEK 450
>NFM_BOVIN (O77788) Neurofilament triplet M protein (160 kDa
neurofilament protein) (Neurofilament medium
polypeptide) (NF-M) (Fragment)
Length = 810
Score = 94.0 bits (232), Expect = 1e-18
Identities = 103/393 (26%), Positives = 164/393 (41%), Gaps = 52/393 (13%)
Query: 48 EEVLEMDKLADDGDVVTE--NAIKAGDGEGIKEDEKVNEGKEIKEDKQADE--------- 96
EE++E K+ D+ + E AI +KE+ K E +E +E ++A+E
Sbjct: 339 EEIIEETKVEDEKSEMEEALTAITEELAVSVKEEVKEEEAEEKEEKEEAEEEVVAAKKSP 398
Query: 97 ----GEELKEDK----KDNGGEERKEDKKVDVGQEVKEDKKVNEGGDIKEE-KKADEGEK 147
ELKE++ ++ G EE +E+++ + +E EG KEE ++ +EGE
Sbjct: 399 VKATAPELKEEEGEKEEEEGQEEEEEEEEAAKSDQAEEGGSEKEGSSEKEEGEQEEEGET 458
Query: 148 LKEDKKDDAAVKIKEDKKVNEG-------EELKEEKKADEGEKLKED--KKDDAGVEIIE 198
E + ++AA + KE+KK+ E EEL E K ++ EK K K +
Sbjct: 459 EAEGEGEEAAAEAKEEKKMEEKAEEVAPKEELAAEAKVEKPEKAKSPVAKSPTTKSPTAK 518
Query: 199 DKKVNEGEELEEEKKAEGEELKEDKKVDA-GDEIEEDKKDDNGFEDDKLSEETELSKEER 257
+ E K+ + K A E + + + S +
Sbjct: 519 SPEAKSPEAKSPTAKSPTAKSPVAKSPTAKSPEAKSPEAKSPTAKSPTAKSPAAKSPAPK 578
Query: 258 ESVEAKKPELDAMDE-----ESILEGKDEGSE---KEKSQKDREDDKDKVDNKSNEENIK 309
VE KP+ +A E E + E K E E +EK++K E KD + K E +K
Sbjct: 579 SPVEEVKPKAEAGAEKGEQKEKVEEEKKEAKESPKEEKAEKKEEKPKDVPEKKKAESPVK 638
Query: 310 VEKRLKKRGKGKVNGENVKKKMKELKKIEDIPEAKDESIEKERSRDEEVGDKEKVGGENV 369
E +K+ K + +K+ KE E K + EKE+ + EEVG KE+ G +
Sbjct: 639 AESPVKEEVPAKPVKVSPEKEAKE--------EEKPQEKEKEKEKVEEVGGKEEGGLKES 690
Query: 370 KKK------MKELKEAEPTTPTTNRPVRERKSV 396
+K+ E KE E T E K V
Sbjct: 691 RKEDIAINGEVEGKEEEQETKEKGSGGEEEKGV 723
Score = 57.8 bits (138), Expect = 1e-07
Identities = 128/642 (19%), Positives = 233/642 (35%), Gaps = 106/642 (16%)
Query: 29 QDLKEDGIKAMEVDKKADG-------------EEVLEMDKLADDGDVVTENA--IKAGDG 73
+D++E + +E+DKK EEV ++ + E +K
Sbjct: 92 KDIEESSLVKVELDKKVQSLQDEVAFLRSNHEEEVADLLAQIQASHITVERKDYLKTDIS 151
Query: 74 EGIKEDEKVNEGKEIKEDKQADEGEELKEDKKDNGGEERKEDKKVDVGQEVKEDKKVNEG 133
+KE E + QA+E + + K E+ KE + +E+ E ++ +
Sbjct: 152 TALKEIRSQLESHSDQNMHQAEEWFKCRYAKLTEAAEQNKEAIR-SAKEEIAEYRRQLQS 210
Query: 134 GDIKEEKKADEGEKLKEDKKDDAAVKIKEDKKVNEG--EELKEEKKADEGEKLKE----- 186
I+ E E L E + D + D + ++L+ E + + E +
Sbjct: 211 KSIELESVRGTKESL-ERQLSDIEERHNHDLSSYQDTIQQLENELRGTKWEMARHLREYQ 269
Query: 187 ---DKKDDAGVEIIEDKKVNEGEELEEEKKAEGEE----LKEDKKVDAGDEIEEDK---- 235
+ K +EI +K+ EGEE A + +I++ K
Sbjct: 270 DLLNVKMALDIEIAAYRKLLEGEETRFSTFAGSITGPLYTHRQPSIAISSKIQKTKVEAP 329
Query: 236 --KDDNGFEDDKLSEETELSKEERESVEAKKPELDAMDEESILEGKDEGSEKEKSQKDRE 293
K + F ++ + EET++ E+ E EA L A+ EE + K+E E+E +K+ +
Sbjct: 330 KLKVQHKFVEE-IIEETKVEDEKSEMEEA----LTAITEELAVSVKEEVKEEEAEEKEEK 384
Query: 294 DDKDKVDNKSNEENIKVEKRLKKRGKGKVNGENVKKKMKELKKIEDIPEAKDESIEKERS 353
++ + EE + +K VK ELK+ E E ++ E+E
Sbjct: 385 EEAE-------EEVVAAKK------------SPVKATAPELKEEEGEKEEEEGQEEEEEE 425
Query: 354 RDEEVGDKEKVGGENVKKKMKELKEAEPTTPTTNRPVRERKSVERLVESYDRDASKEFQI 413
+ D+ + GG K+ E +E E + + E E +A+ E +
Sbjct: 426 EEAAKSDQAEEGGSE-KEGSSEKEEGE-----------QEEEGETEAEGEGEEAAAEAKE 473
Query: 414 EEGRGTPLKNIPNVAFKLSRRKVDDTLKFLHTILFCRRGKAAVIKKNILRFSGFVWHENE 473
E+ + + + KV+ K + K+ K +
Sbjct: 474 EKKMEEKAEEVAPKEELAAEAKVEKPEKAKSPVAKSPTTKSPTAK-------------SP 520
Query: 474 EKQMIKVKEKFDKCNKEKLLEFSDLLDVPVGNANTRKEDIIAKLIDFLVAPQVTKSVLLA 533
E + + K K K PV + T K +P+ +
Sbjct: 521 EAKSPEAKSPTAKSPTAKS---------PVAKSPTAKSPEAK-------SPEAKSPTAKS 564
Query: 534 EQEKSAKEKRIAKQGSTGSGTPTSRRSAKSRKKIEDSSIAEKKKTATDTESESEKDEENK 593
KS K A + P + A+ ++ E + E+KK A ES E+ E K
Sbjct: 565 PTAKSPAAKSPAPKSPVEEVKPKAEAGAEKGEQKE--KVEEEKKEAK--ESPKEEKAEKK 620
Query: 594 EENEIDVSDKSEDEKPIKGKKHIAKQGSSRSGTASSRRSAKE 635
EE DV +K + E P+K + + ++ ++ S + AKE
Sbjct: 621 EEKPKDVPEKKKAESPVKAESPVKEEVPAKPVKVSPEKEAKE 662
Score = 57.4 bits (137), Expect = 1e-07
Identities = 60/234 (25%), Positives = 114/234 (48%), Gaps = 23/234 (9%)
Query: 88 IKEDKQADEGEELKEDKKDNGGEERKEDKKVDVGQEVKEDKKVNEGGDIKEEKKADEGEK 147
++E K E K ++K+ EE+KE K+ +E K +KK + D+ E+KKA+ K
Sbjct: 581 VEEVKPKAEAGAEKGEQKEKVEEEKKEAKESP--KEEKAEKKEEKPKDVPEKKKAESPVK 638
Query: 148 LKEDKKDDAAVKIKEDKKVNEGEELKEEKKADEGEKLKEDKKDDAGVEIIEDKKVNEGEE 207
+ K++ K ++ EK+A E EK +E +K+ VE + K E
Sbjct: 639 AESPVKEEVPAK---------PVKVSPEKEAKEEEKPQEKEKEKEKVEEVGGK---EEGG 686
Query: 208 LEEEKKAEGEELKEDKKVDAGDEIEEDKKDDNGFEDDK--LSEETELSKEERESVEAKKP 265
L+E +K E++ + +V+ +E +E K+ +G E++K ++ ++S + + K
Sbjct: 687 LKESRK---EDIAINGEVEGKEEEQETKEKGSGGEEEKGVVTNGLDVSPGDEKKGGDKSE 743
Query: 266 E---LDAMDEESILEGKDEGSEKEKSQKDREDDKDKVDNKSNEENIKVEKRLKK 316
E + M E+ EG D G+ K ++ K + ++ EE + K+++K
Sbjct: 744 EKVVVTKMVEKITSEGGD-GATKYITKSVTVTQKVEEHEETFEEKLVSTKKVEK 796
Score = 39.7 bits (91), Expect = 0.032
Identities = 107/534 (20%), Positives = 205/534 (38%), Gaps = 83/534 (15%)
Query: 164 KKVNEGEELKEEKKADEGEKLKEDKKDDAGVEIIEDKKVNEGEELEEEKKAEGEELKEDK 223
+KV+ E+ +E +A E + L++ + A + D+++ E E E +++ D
Sbjct: 1 EKVHYLEQQNKEIEA-EIQALRQKQASHAQLGDAYDQEIRELRATLEMVNHEKAQVQLDS 59
Query: 224 KVDAGDEIEED--KKDDNGFEDDKLSEETE-----LSKEERES----VEAKKPELDAMDE 272
D +EED + + E+ +L ++TE L K+ ES VE K DE
Sbjct: 60 -----DHLEEDIHRLKERFEEEARLRDDTEAAIRALRKDIEESSLVKVELDKKVQSLQDE 114
Query: 273 ESILEGKDEGSEKE-----KSQKDREDDKDKVDNKSNEENIKVEKRLKKRGKGKVNGENV 327
+ L E + ++ + KD + + ++ +L+ ++
Sbjct: 115 VAFLRSNHEEEVADLLAQIQASHITVERKDYLKTDISTALKEIRSQLESHSDQNMHQAEE 174
Query: 328 KKKMKELKKIEDIPEAKDESIEKERSRDEEVGDKEKVGGENVKKKMKELKEAEPTTPTTN 387
K + K + EA +++ E RS EE+ + + ++ K EL+ T +
Sbjct: 175 WFKCRYAK----LTEAAEQNKEAIRSAKEEIAEYRR----QLQSKSIELESVRGTKESLE 226
Query: 388 RPVRERKSVERLVESYDRDASKEFQIEEGRGTP---------LKNIPNVAFKLS------ 432
R + + + S +D ++ + E RGT +++ NV L
Sbjct: 227 RQLSDIEERHNHDLSSYQDTIQQLE-NELRGTKWEMARHLREYQDLLNVKMALDIEIAAY 285
Query: 433 RRKVDDTLKFLHTILFCRRGKAAVIKKNILRFSGFVWHENEEKQMIKVKEKF-------D 485
R+ ++ T G ++ + S + E +KV+ KF
Sbjct: 286 RKLLEGEETRFSTFAGSITGPLYTHRQPSIAISSKIQKTKVEAPKLKVQHKFVEEIIEET 345
Query: 486 KCNKEK------LLEFSDLLDVPV--------GNANTRKEDIIAKLIDFLVAPQVTKSVL 531
K EK L ++ L V V KE+ +++ +P +
Sbjct: 346 KVEDEKSEMEEALTAITEELAVSVKEEVKEEEAEEKEEKEEAEEEVVAAKKSPVKATAPE 405
Query: 532 LAEQEKSAKEKRIAKQGSTGSGTPTSRRSAKSRKKIEDSSIAEKKKTATDTESESE---- 587
L E+E +E+ ++ S ++ + + E SS E+ + + E+E+E
Sbjct: 406 LKEEEGEKEEEEGQEEEEEEEEAAKSDQAEEGGSEKEGSSEKEEGEQEEEGETEAEGEGE 465
Query: 588 ------KDEENKEENEIDVSDKSE------DEKPIKGKKHIAKQGSSRSGTASS 629
K+E+ EE +V+ K E EKP K K +AK +++S TA S
Sbjct: 466 EAAAEAKEEKKMEEKAEEVAPKEELAAEAKVEKPEKAKSPVAKSPTTKSPTAKS 519
Score = 39.3 bits (90), Expect = 0.041
Identities = 57/201 (28%), Positives = 82/201 (40%), Gaps = 31/201 (15%)
Query: 3 GNHLDDSSEKKDLEPKGGKIFEDNAVQDLKEDGIKAMEVDKKADG----EEVLEMDKLAD 58
G + EK + E K K + KE+ K + KKA+ E ++ + A
Sbjct: 591 GAEKGEQKEKVEEEKKEAKESPKEEKAEKKEEKPKDVPEKKKAESPVKAESPVKEEVPAK 650
Query: 59 DGDVVTENAIKAGDGEGIKEDEKVNEGKEIKEDKQADEG---EELKEDKKDNGGEERKED 115
V E K E K EK E ++++E +EG E KED NG E KE+
Sbjct: 651 PVKVSPEKEAK----EEEKPQEKEKEKEKVEEVGGKEEGGLKESRKEDIAINGEVEGKEE 706
Query: 116 KK--VDVGQEVKEDKKV------------NEGGDIKEEK--KADEGEKLKEDKKDDAAVK 159
++ + G +E+K V +GGD EEK EK+ + D A
Sbjct: 707 EQETKEKGSGGEEEKGVVTNGLDVSPGDEKKGGDKSEEKVVVTKMVEKITSEGGDGATKY 766
Query: 160 IKED----KKVNEGEELKEEK 176
I + +KV E EE EEK
Sbjct: 767 ITKSVTVTQKVEEHEETFEEK 787
>NSB1_HUMAN (P82970) Nucleosomal binding protein 1
Length = 282
Score = 92.8 bits (229), Expect = 3e-18
Identities = 75/235 (31%), Positives = 123/235 (51%), Gaps = 18/235 (7%)
Query: 8 DSSEKKDLEPKGGKIFEDNAVQDLKEDGIKAMEVDKKADGEEVLEMDKLADDGDVVTENA 67
D+S + E K + E++ ++ K K E A +E++E+ + ++ + TE
Sbjct: 57 DTSAQAVAETKQEAVVEEDYNENAKNGEAKITEAP--ASEKEIVEVKE--ENIEDATEKG 112
Query: 68 IKAGDGEGIKEDEKVNEGKEIKEDKQADEGEELKEDKKDNGGEERKEDKKVDVGQEVKED 127
+ + + + + KE +ED+ ++GE KEDK + G E+ KEDK G E ED
Sbjct: 113 GEKKEAVAAEVKNEEEDQKEDEEDQNEEKGEAGKEDKDEKGEEDGKEDKN---GNEKGED 169
Query: 128 KKVNEGGDIKEEKK--ADEGEKLKEDKKDDAAVKIKEDKKVNEGEELKEEKKADEGEKLK 185
K E G E+ K ++G++ ED+K++ K D K NE + K +KK + K+K
Sbjct: 170 AKEKEDGKKGEDGKGNGEDGKEKGEDEKEEEDRKETGDGKENEDGKEKGDKKEGKDVKVK 229
Query: 186 EDKKDDAGVEIIEDKKVNEGEELEEEKKAEGEELKEDKKVDAGDEIEED--KKDD 238
ED+K+ ED K +EG EEE E E+LKE+++ DEI+ED KK++
Sbjct: 230 EDEKER------EDGKEDEGGN-EEEAGKEKEDLKEEEEGKEEDEIKEDDGKKEE 277
Score = 84.3 bits (207), Expect = 1e-15
Identities = 86/301 (28%), Positives = 145/301 (47%), Gaps = 38/301 (12%)
Query: 92 KQADEGEELKEDKKDNGGEERKEDKKVDVGQEVK-----EDKKVNEGGDIKEEKKADEGE 146
K A +G+ +E K+ + R V V EVK +K+ D+ EE D
Sbjct: 5 KAAGQGDMRQEPKRRSA---RLSAMLVPVTPEVKPKRTSSSRKMKTKSDMMEEN-IDTSA 60
Query: 147 KLKEDKKDDAAVKIKEDKKVNEGEELKEEKKADEGE--KLKEDKKDDAGVEIIEDKKVNE 204
+ + K +A V+ ++ GE E A E E ++KE+ +DA + E K+
Sbjct: 61 QAVAETKQEAVVEEDYNENAKNGEAKITEAPASEKEIVEVKEENIEDATEKGGEKKEAVA 120
Query: 205 GE-ELEEEKKAEGEELKEDKKVDAGDEIEEDKKDDNGFEDDKLSEETELSKEERESVEAK 263
E + EEE + E EE + ++K +AG E +++K +++G ED +E+ E +KE+ + K
Sbjct: 121 AEVKNEEEDQKEDEEDQNEEKGEAGKEDKDEKGEEDGKEDKNGNEKGEDAKEKEDG---K 177
Query: 264 KPELDAMDEESILEGK---DEGSEKEKSQKDREDDKDKVDNKSNEENIKVEKRLKKRGKG 320
K E +GK ++G EK + +K+ ED K+ D K NE+ EK KK GK
Sbjct: 178 KGE----------DGKGNGEDGKEKGEDEKEEEDRKETGDGKENEDG--KEKGDKKEGKD 225
Query: 321 KVNGENVKKKMKELKKIEDIPEAKDESIEKERSRDEEVGDKEKVGGENVKKKMKELKEAE 380
K+KE +K + + + E+E +++E +E+ G E + K + K+ E
Sbjct: 226 V--------KVKEDEKEREDGKEDEGGNEEEAGKEKEDLKEEEEGKEEDEIKEDDGKKEE 277
Query: 381 P 381
P
Sbjct: 278 P 278
Score = 82.0 bits (201), Expect = 6e-15
Identities = 74/255 (29%), Positives = 130/255 (50%), Gaps = 39/255 (15%)
Query: 27 AVQDLKEDGIKAMEVDKKADGEEVLEMDKLADDGDVVT---ENAIKAGDGEGIKEDEKVN 83
AV + K++ + + ++ A E + A + ++V EN A + G K++
Sbjct: 62 AVAETKQEAVVEEDYNENAKNGEAKITEAPASEKEIVEVKEENIEDATEKGGEKKEAVAA 121
Query: 84 EGKEIKEDKQADEGEELKEDKKDNGGEERKEDKKVDVGQEVKEDKKVNEGGDIKEEKKAD 143
E K +ED++ DE ED+ + GE KEDK ++ KEDK NE G+ +EK +
Sbjct: 122 EVKNEEEDQKEDE-----EDQNEEKGEAGKEDKDEKGEEDGKEDKNGNEKGEDAKEK--E 174
Query: 144 EGEKLKEDKKDDAAVKIKEDKKVNEGEELKEEKKADEGEKLKEDKKDDAGVEIIEDKKVN 203
+G+K ED K N GE+ KE+ E EK +ED+K+ + K+
Sbjct: 175 DGKK-------------GEDGKGN-GEDGKEK---GEDEKEEEDRKETG-----DGKENE 212
Query: 204 EGEELEEEKKAEGEELKEDKKVDAGDEIEEDKKDDNGFEDDKLSEETELSKEE--RESVE 261
+G+E ++K+ + ++KED+K E E+ K+D+ G E++ E+ +L +EE +E E
Sbjct: 213 DGKEKGDKKEGKDVKVKEDEK-----EREDGKEDEGGNEEEAGKEKEDLKEEEEGKEEDE 267
Query: 262 AKKPELDAMDEESIL 276
K+ + + +SI+
Sbjct: 268 IKEDDGKKEEPQSIV 282
Score = 79.0 bits (193), Expect = 5e-14
Identities = 66/237 (27%), Positives = 118/237 (48%), Gaps = 13/237 (5%)
Query: 39 MEVDKKADGEEVLEMDKLADDGDVVTENAIKAGDGEGIKEDEKVNEGKEIKEDKQADEGE 98
ME + + V E + A + ENA K G+ + + E E+KE+ D E
Sbjct: 52 MEENIDTSAQAVAETKQEAVVEEDYNENA-KNGEAKITEAPASEKEIVEVKEENIEDATE 110
Query: 99 ELKEDKKDNGGEERKEDKKVDVGQEVKEDKKVNEGGDIKEEKKADEGEKLKEDKKDDAAV 158
+ E K+ E + E++ +E + ++K G + K+EK ++G++ K +
Sbjct: 111 KGGEKKEAVAAEVKNEEEDQKEDEEDQNEEKGEAGKEDKDEKGEEDGKEDKNGNEKGEDA 170
Query: 159 KIKED-KKVNEGEELKEE-KKADEGEKLKEDKKDDAGVEIIEDKKVNEGEELEEEKKAEG 216
K KED KK +G+ E+ K+ E EK +ED+K+ + K+ +G+E ++K+ +
Sbjct: 171 KEKEDGKKGEDGKGNGEDGKEKGEDEKEEEDRKETG-----DGKENEDGKEKGDKKEGKD 225
Query: 217 EELKEDKKVDAGDEIEEDKKDDNGFEDDKLSEETELSKEERESVEAKKPELDAMDEE 273
++KED+K E E+ K+D+ G E++ E+ +L +EE E + E D EE
Sbjct: 226 VKVKEDEK-----EREDGKEDEGGNEEEAGKEKEDLKEEEEGKEEDEIKEDDGKKEE 277
Score = 77.8 bits (190), Expect = 1e-13
Identities = 75/242 (30%), Positives = 119/242 (48%), Gaps = 27/242 (11%)
Query: 54 DKLADDGDVVTENAIKAGDGEGIKEDEKVNEGKEIKEDKQADEGEELKEDKKDNGGEERK 113
+ + V E +A E E+ K E K + E E+KE+ ++ E+
Sbjct: 54 ENIDTSAQAVAETKQEAVVEEDYNENAKNGEAKITEAPASEKEIVEVKEENIEDATEKGG 113
Query: 114 EDKKVDVGQEVK---EDKKVNEGGDIKEEKKADEGEKLKEDKKDDAAVKIKEDKKVNE-G 169
E KK V EVK ED+K +E E++ ++GE KEDK + KEDK NE G
Sbjct: 114 E-KKEAVAAEVKNEEEDQKEDE-----EDQNEEKGEAGKEDKDEKGEEDGKEDKNGNEKG 167
Query: 170 EELKEEKKADEGEKLKEDKKDDAGVEIIEDKKVNEGEELEEEKKAEGEEL-----KEDKK 224
E+ KE++ +GE K + +D G E ED+K EE + ++ +G+E K DKK
Sbjct: 168 EDAKEKEDGKKGEDGKGNGED--GKEKGEDEK----EEEDRKETGDGKENEDGKEKGDKK 221
Query: 225 VDAGDEIEEDKKDDNGFEDDKLSEETELSKEERESVEAKKPELDAMDEESILEGKDEGSE 284
+++ED+K+ ++D+ E E KE+ E K E + +E+ I E D+G +
Sbjct: 222 EGKDVKVKEDEKEREDGKEDEGGNEEEAGKEK----EDLKEEEEGKEEDEIKE--DDGKK 275
Query: 285 KE 286
+E
Sbjct: 276 EE 277
Score = 75.1 bits (183), Expect = 7e-13
Identities = 76/252 (30%), Positives = 119/252 (47%), Gaps = 32/252 (12%)
Query: 64 TENAIKAGDGEGIKEDEKVNEGKEIKEDKQADEGEELKEDKKDNGGEE-----RKEDKKV 118
T ++ K + E+ + + E KQ EE + NG + E + V
Sbjct: 39 TSSSRKMKTKSDMMEENIDTSAQAVAETKQEAVVEEDYNENAKNGEAKITEAPASEKEIV 98
Query: 119 DVGQEVKEDKKVNEGGDIKEEKKADEGEKLKEDKKDDAAVKIKEDKKVNEGEELKEEKKA 178
+V +E ED E G K+E A E + +ED+K+D +ED+ +GE KE+K
Sbjct: 99 EVKEENIED--ATEKGGEKKEAVAAEVKNEEEDQKED-----EEDQNEEKGEAGKEDKDE 151
Query: 179 DEGEKLKEDKKDDAGVEIIEDKKVNEGEELEEEKKAEGE---ELKEDKKVDAGDEIEEDK 235
E KEDK G E ED K E + E+ K GE E ED+K EED+
Sbjct: 152 KGEEDGKEDKN---GNEKGEDAKEKEDGKKGEDGKGNGEDGKEKGEDEKE------EEDR 202
Query: 236 KDDNGFEDDKLSEETELSKEERESVEAKKPELDAMDEESILEGK-DEGSEKEKSQKDRED 294
K+ D K +E+ + +++E + K E DE+ +GK DEG +E++ K++ED
Sbjct: 203 KETG---DGKENEDGKEKGDKKEGKDVKVKE----DEKEREDGKEDEGGNEEEAGKEKED 255
Query: 295 DKDKVDNKSNEE 306
K++ + K +E
Sbjct: 256 LKEEEEGKEEDE 267
Score = 73.2 bits (178), Expect = 3e-12
Identities = 67/245 (27%), Positives = 113/245 (45%), Gaps = 19/245 (7%)
Query: 86 KEIKEDKQADEGEELKEDKKDNGGEERKEDKKVDVGQEVKEDKKVNEGGDIKEEKKAD-E 144
K ++ ++ E+ D + E K+ V +E + N I E ++ E
Sbjct: 37 KRTSSSRKMKTKSDMMEENIDTSAQAVAETKQEAVVEEDYNENAKNGEAKITEAPASEKE 96
Query: 145 GEKLKEDKKDDAAVKIKEDKKVNEGEELKEEKKADEGEKLKEDKKDDAGVEIIEDKKVNE 204
++KE+ +DA K E K+ E EE+ E E+ + ++K +AG E ++K +
Sbjct: 97 IVEVKEENIEDATEKGGEKKEAVAAEVKNEEEDQKEDEEDQNEEKGEAGKEDKDEKGEED 156
Query: 205 GEELEEEKKAEGEELKEDKKVDAGDEIEEDKKDDNG---FEDDKLSEETELSKEERESVE 261
G+E ++ +GE+ KE E+ KK ++G ED K E E +E+R+
Sbjct: 157 GKE-DKNGNEKGEDAKEK---------EDGKKGEDGKGNGEDGKEKGEDEKEEEDRKETG 206
Query: 262 AKKPELDAMDEESILEGKDEGSEKEKSQKDREDDKDKVDNKSNEENIKVEKR-LKKRGKG 320
K D ++ EGKD + ++ +K+RED K+ D NEE EK LK+ +G
Sbjct: 207 DGKENEDGKEKGDKKEGKD--VKVKEDEKEREDGKE--DEGGNEEEAGKEKEDLKEEEEG 262
Query: 321 KVNGE 325
K E
Sbjct: 263 KEEDE 267
Score = 59.3 bits (142), Expect = 4e-08
Identities = 44/152 (28%), Positives = 81/152 (52%), Gaps = 6/152 (3%)
Query: 7 DDSSEKKDLEPKGGKIFEDNAVQDLKEDGIKAMEVDKKADGEEVLEMDKLADDGDVVTEN 66
D +++D + G+ +++ + +EDG + ++K + + E K +DG E+
Sbjct: 129 DQKEDEEDQNEEKGEAGKEDKDEKGEEDGKEDKNGNEKGEDAKEKEDGKKGEDGKGNGED 188
Query: 67 AIKAGDGEGIKEDEK-VNEGKEIKEDKQADEGEELKEDKKDNGGEERKEDKKVDVGQEVK 125
+ G+ E +ED K +GKE ++ K+ + +E K D K E+ +ED K D G +
Sbjct: 189 GKEKGEDEKEEEDRKETGDGKENEDGKEKGDKKEGK-DVKVKEDEKEREDGKEDEGGNEE 247
Query: 126 EDKKVNEGGDIKEEKKADEGEKLKED--KKDD 155
E K E D+KEE++ E +++KED KK++
Sbjct: 248 EAGKEKE--DLKEEEEGKEEDEIKEDDGKKEE 277
Score = 56.6 bits (135), Expect = 3e-07
Identities = 69/279 (24%), Positives = 119/279 (41%), Gaps = 38/279 (13%)
Query: 172 LKEEKKADEGEKLKEDKKDDAGVEII------EDKKVNEGEELEEEKKAEGEELKEDKKV 225
+ + K A +G+ +E K+ A + + E K + + K++ E D
Sbjct: 1 MPKRKAAGQGDMRQEPKRRSARLSAMLVPVTPEVKPKRTSSSRKMKTKSDMMEENIDTSA 60
Query: 226 DAGDEIEEDKKDDNGFEDDKLSEE---TELSKEERESVEAKKPEL-DAMD---EESILEG 278
A E +++ + + ++ + E TE E+E VE K+ + DA + E+
Sbjct: 61 QAVAETKQEAVVEEDYNENAKNGEAKITEAPASEKEIVEVKEENIEDATEKGGEKKEAVA 120
Query: 279 KDEGSEKEKSQKDRED-----------DKD-------KVDNKSNE--ENIKVEKRLKKRG 318
+ +E+E ++D ED DKD K D NE E+ K ++ KK
Sbjct: 121 AEVKNEEEDQKEDEEDQNEEKGEAGKEDKDEKGEEDGKEDKNGNEKGEDAKEKEDGKKGE 180
Query: 319 KGKVNGENVKKKMKELKKIEDIPEAKDESIEKERSRDEEVGDKEKVGGENVKKKMKELKE 378
GK NGE+ K+K ++ K+ ED E D KE +E GDK++ G++VK K E +
Sbjct: 181 DGKGNGEDGKEKGEDEKEEEDRKETGD---GKENEDGKEKGDKKE--GKDVKVKEDEKER 235
Query: 379 AEPTTPTTNRPVRERKSVERLVESYDRDASKEFQIEEGR 417
+ K E L E + E + ++G+
Sbjct: 236 EDGKEDEGGNEEEAGKEKEDLKEEEEGKEEDEIKEDDGK 274
Score = 37.7 bits (86), Expect = 0.12
Identities = 26/102 (25%), Positives = 49/102 (47%), Gaps = 8/102 (7%)
Query: 534 EQEKSAKEKRIAKQGSTGSGTPTSRRSAKSRKKIEDSSIAEKKKTATDTESESEKDEENK 593
E+ + AKEK K+G G G + +K E+ ++K+T E+E K++ +K
Sbjct: 165 EKGEDAKEKEDGKKGEDGKGNGEDGKEKGEDEKEEE----DRKETGDGKENEDGKEKGDK 220
Query: 594 EENEIDVSDKSEDEKPIKGKKHIAKQGSSRSGTASSRRSAKE 635
+E + DV K ++++ GK+ +G + + KE
Sbjct: 221 KEGK-DVKVKEDEKEREDGKE---DEGGNEEEAGKEKEDLKE 258
>CYL1_HUMAN (P35663) Cylicin I (Multiple-band polypeptide I)
(Fragment)
Length = 598
Score = 88.2 bits (217), Expect = 8e-17
Identities = 82/341 (24%), Positives = 153/341 (44%), Gaps = 32/341 (9%)
Query: 65 ENAIKAGDGEGIKEDEKVNEGKEIKED-KQADEGEELKEDKKDNGGE------ERKEDKK 117
+NA K+ D E + + K++K++ K+ D+ +++K+D + E ERK+ KK
Sbjct: 237 KNAKKSSDAESEDSKDAKKDSKKVKKNVKKDDKKKDVKKDTESTDAESGDSKDERKDTKK 296
Query: 118 VDVGQEVKEDKKVN----------EGGDIKEEKKADEGEKLKEDKKDDAAVKIKEDKKVN 167
D + K+DKK + E GD K+ + K K K DD K K+ KK+
Sbjct: 297 -DKKKLKKDDKKKDTKKYPESTDTESGDAKDARNDSRNLK-KASKNDD---KKKDAKKIT 351
Query: 168 EGEELKEEKKADEGEK-LKEDKKDDAGVEIIEDKKVNEGEELEEEKKAEGEELKEDKKVD 226
+ + E ++ E +K K+DKKD K E + + E K + ++ K+D+K
Sbjct: 352 FSTDSESELESKESQKDEKKDKKDSKTDNKKSVKNDEESTDADSEPKGDSKKGKKDEKKG 411
Query: 227 AGDEIEEDKKDD--NGFEDDKLSEETELSKEERESVEAKKPELDAMDEESILEGKDEGSE 284
D ++DKK D E ++ + EL K+++ S E K + D + +++ + + +E
Sbjct: 412 KKDSKKDDKKKDAKKNAESTEMESDLELKKDKKHSKEKKGSKKD-IKKDARKDTESTDAE 470
Query: 285 KEKSQKDREDDKDKVDNKSNEENIKVEKRLKKRGKGKVNGENVKKKMKELKKIEDIPEAK 344
++S K K+ E + K K+ + +G + KM E + +
Sbjct: 471 FDESSKTGFKTSTKIKGSDTESEESLYKPGAKKKIDESDGTSANSKM------EGLESKR 524
Query: 345 DESIEKERSRDEEVGDKEKVGGENVKKKMKELKEAEPTTPT 385
+ +++ E G+K G ++ L EP+ P+
Sbjct: 525 GFRMSSKKTTFNEKGEKASTGRVPPSREKPPLPACEPSLPS 565
Score = 78.2 bits (191), Expect = 8e-14
Identities = 78/318 (24%), Positives = 140/318 (43%), Gaps = 39/318 (12%)
Query: 12 KKDLEPKGGKIFEDNAVQDLKEDGIKAMEVDKKADGEEVLEMDKLADD---GDVVTENAI 68
KK+ + ED+ +D K+D K + KK D ++ ++ D + D GD E
Sbjct: 236 KKNAKKSSDAESEDS--KDAKKDSKKVKKNVKKDDKKKDVKKDTESTDAESGDSKDERKD 293
Query: 69 KAGDGEGIKEDEKVNEGKEIKE--DKQADEGEELKEDKKDNGGEERKEDKKVDVGQEVKE 126
D + +K+D+K + K+ E D ++ + ++ + D ++ + +DKK K+
Sbjct: 294 TKKDKKKLKKDDKKKDTKKYPESTDTESGDAKDARNDSRNLKKASKNDDKK-------KD 346
Query: 127 DKKVNEGGDIKEEKKADEGEK-LKEDKKDDAAVKIKEDKKVNEGEELKEEKKADEGEKLK 185
KK+ D + E ++ E +K K+DKKD K K E + E K D + K
Sbjct: 347 AKKITFSTDSESELESKESQKDEKKDKKDSKTDNKKSVKNDEESTDADSEPKGDSKKGKK 406
Query: 186 EDKKDDAGVEIIEDKKVNEGEELEEEKKAEGEELKEDKKVDAGDEIEEDKKDDNGFEDDK 245
++KK + + KK + +K AE E++ D E+++DKK +K
Sbjct: 407 DEKKGKKDSKKDDKKK-------DAKKNAESTEMESDL------ELKKDKKHSK----EK 449
Query: 246 LSEETELSKEERESVEAKKPELDAMDEESI-----LEGKDEGSEKEKSQKDREDDKDKVD 300
+ ++ K+ R+ E+ E D + ++G D SE+ + + D+ D
Sbjct: 450 KGSKKDIKKDARKDTESTDAEFDESSKTGFKTSTKIKGSDTESEESLYKPGAKKKIDESD 509
Query: 301 NKSNEENIKVEKRLKKRG 318
S N K+E KRG
Sbjct: 510 GTS--ANSKMEGLESKRG 525
Score = 77.4 bits (189), Expect = 1e-13
Identities = 91/425 (21%), Positives = 177/425 (41%), Gaps = 54/425 (12%)
Query: 5 HLDDSSEKKDLEPKGGKIFEDNAVQDLKEDGIKAMEVDKKADGEEVLEMDKLADDGDVVT 64
HL + KK + KGG + ++ K+ G A + K EE + AD + +
Sbjct: 56 HLKKAEYKKSKDEKGGTPLKKDSK---KKGGSYATNPESKQIVEEKTKRQNEADKTPLKS 112
Query: 65 ENAIKAGDGEGIKEDEKVNEGKEIKEDKQADEGEELKEDKKDNGGEERKEDKKVDVGQEV 124
+ + E K+ + +E ++ + ++DKKD+ ++ + +
Sbjct: 113 SH-----ENEQSKKSKSSSETNPESQNSKTVSKNCSQKDKKDSKNSKKTNTEFLHTKNNP 167
Query: 125 KEDKKVNEGG-----DIKEEKKADEGEKLKEDKKDDAAVKI------------------- 160
K+D K ++ +I E + + + DD ++
Sbjct: 168 KKDLKRSKTSNDPISEICSENSLNVDFLMLVGQSDDESINFDAWLRNYSQNNSKNYSLKY 227
Query: 161 ----KEDKKVN-------EGEELKEEKKADEGEKLKED-KKDDAGVEIIEDKKVNEGEEL 208
K+D K N E E+ K+ KK + +K+K++ KKDD ++ +D + + E
Sbjct: 228 TKYTKKDTKKNAKKSSDAESEDSKDAKK--DSKKVKKNVKKDDKKKDVKKDTESTDAES- 284
Query: 209 EEEKKAEGEELKEDKKVDAGDEIEEDKKDDNGFEDDKLSEETELSKEERESVEAKKPELD 268
+ K E ++ K+DKK D+ ++D K D + + + + R +A K +
Sbjct: 285 -GDSKDERKDTKKDKKKLKKDDKKKDTKKYPESTDTESGDAKDARNDSRNLKKASKNDDK 343
Query: 269 AMDEESILEGKDEGSEKEKSQKDREDDKDKVDNKS-NEENIKVEKR-----LKKRGKGKV 322
D + I D SE E + +++ KDK D+K+ N++++K ++ + +G K
Sbjct: 344 KKDAKKITFSTDSESELESKESQKDEKKDKKDSKTDNKKSVKNDEESTDADSEPKGDSKK 403
Query: 323 NGENVKKKMKELKKIEDIPEAKDESIEKERSRDEEVGDKEKVGGENVKKKMKELKEAEPT 382
++ KK K+ KK + +AK + E D E+ +K E K K+A
Sbjct: 404 GKKDEKKGKKDSKKDDKKKDAKKNAESTEMESDLELKKDKKHSKEKKGSKKDIKKDARKD 463
Query: 383 TPTTN 387
T +T+
Sbjct: 464 TESTD 468
Score = 74.7 bits (182), Expect = 9e-13
Identities = 108/464 (23%), Positives = 193/464 (41%), Gaps = 80/464 (17%)
Query: 9 SSEKKDLEPKGGKIFEDNAVQDLKEDGIKAMEVDK-----KADGEEVLEMDKLADD--GD 61
SS + + E + K N Q K+D + + + K + ++ L+ K ++D +
Sbjct: 124 SSSETNPESQNSKTVSKNCSQKDKKDSKNSKKTNTEFLHTKNNPKKDLKRSKTSNDPISE 183
Query: 62 VVTENAIKAGDGE--GIKEDEKVNEGKEIKEDKQAD-EGEELKEDKKDNGGEERKEDKKV 118
+ +EN++ G +DE +N ++ Q + + LK K ++ K
Sbjct: 184 ICSENSLNVDFLMLVGQSDDESINFDAWLRNYSQNNSKNYSLKYTKYTKKDTKKNAKKSS 243
Query: 119 DVGQEVKEDKKVNEGGDIKEEKKADEGEKLKEDKKDDAAVKIKEDKKVNEGE------EL 172
D E +D K K+ KK + K K+DKK D +K+D + + E E
Sbjct: 244 DAESEDSKDAK-------KDSKKVKKNVK-KDDKKKD----VKKDTESTDAESGDSKDER 291
Query: 173 KEEKKADEGEKLKEDKKDDAGVEIIEDKKVNEGEELEE-------------EKKAEGEEL 219
K+ KK D+ + K+DKK D KK E + E +K ++ ++
Sbjct: 292 KDTKK-DKKKLKKDDKKKDT-------KKYPESTDTESGDAKDARNDSRNLKKASKNDDK 343
Query: 220 KEDKK-----VDAGDEIE--EDKKDDNGFEDDKLSEETELSKEERESVEAKKPELDAMDE 272
K+D K D+ E+E E +KD+ + D ++ + K + ES +A D
Sbjct: 344 KKDAKKITFSTDSESELESKESQKDEKKDKKDSKTDNKKSVKNDEESTDA--------DS 395
Query: 273 ESILEGKDEGSEKEKSQKDREDDKDKVDNKSNEENIKVEKRLKKRGKGKVNGENVKKKMK 332
E + K +++K +KD + D K D K N E+ ++E L+ + K K + + K K
Sbjct: 396 EPKGDSKKGKKDEKKGKKDSKKDDKKKDAKKNAESTEMESDLELK-KDKKHSKEKKGSKK 454
Query: 333 ELKKIEDIPEAKD-ESIEKERSRDEEVGDK--EKVGGENVKKK--------MKELKEAEP 381
++KK KD ES + E + G K K+ G + + + K++ E++
Sbjct: 455 DIKK----DARKDTESTDAEFDESSKTGFKTSTKIKGSDTESEESLYKPGAKKKIDESDG 510
Query: 382 TTPTTNRPVRERKSVERLVESYDRDASKEFQIEEGRGTPLKNIP 425
T+ + E K R+ K + GR P + P
Sbjct: 511 TSANSKMEGLESKRGFRMSSKKTTFNEKGEKASTGRVPPSREKP 554
Score = 69.7 bits (169), Expect = 3e-11
Identities = 66/312 (21%), Positives = 127/312 (40%), Gaps = 47/312 (15%)
Query: 7 DDSSEKKDLEPKGGKIFEDNAVQDLKED---------GIKAMEVDKKADGEEVLEMDKLA 57
D KKD + + +D+ +D+K+D K D K D +++ + DK
Sbjct: 249 DSKDAKKDSKKVKKNVKKDDKKKDVKKDTESTDAESGDSKDERKDTKKDKKKLKKDDKKK 308
Query: 58 DDGDVVTENAIKAGDGEGI-----------KEDEKVNEGKEI-----------KEDKQAD 95
D ++GD + K D+K + K+I ++ Q D
Sbjct: 309 DTKKYPESTDTESGDAKDARNDSRNLKKASKNDDKKKDAKKITFSTDSESELESKESQKD 368
Query: 96 EGEELKEDKKDNGGEERKEDKKVDVGQEVKEDKKVNEGGDIKEEKKADEGEKLKEDKKDD 155
E ++ K+ K DN + +++ D E K D K + + K +K + + +K K+ KK+
Sbjct: 369 EKKDKKDSKTDNKKSVKNDEESTDADSEPKGDSKKGKKDEKKGKKDSKKDDKKKDAKKNA 428
Query: 156 AAVKIKEDKKVNEGEELKEEKKADEGEKLKEDKKDDAGVEIIEDKKVNEGEELEEEKKAE 215
+ +++ D ++ + ++ +EKK + + K+ +KD + D+ G + + K
Sbjct: 429 ESTEMESDLELKKDKKHSKEKKGSKKDIKKDARKDTESTDAEFDESSKTGFKTSTKIKGS 488
Query: 216 GEELKED-------KKVDAGDEIEEDKK-----DDNGF----EDDKLSEETELSKEERES 259
E +E KK+D D + K GF + +E+ E + R
Sbjct: 489 DTESEESLYKPGAKKKIDESDGTSANSKMEGLESKRGFRMSSKKTTFNEKGEKASTGRVP 548
Query: 260 VEAKKPELDAMD 271
+KP L A +
Sbjct: 549 PSREKPPLPACE 560
Score = 52.4 bits (124), Expect = 5e-06
Identities = 85/404 (21%), Positives = 155/404 (38%), Gaps = 67/404 (16%)
Query: 249 ETELSKEERESVEAKKPELDAMDEESILEGKDEGSEKEKSQKDREDDKDKVDNKSNEENI 308
E + SK+E+ KK D+ + E + + + R+++ DK KS+ EN
Sbjct: 61 EYKKSKDEKGGTPLKK---DSKKKGGSYATNPESKQIVEEKTKRQNEADKTPLKSSHEN- 116
Query: 309 KVEKRLKKRGKGKVNGENVKKKMKELKKIEDIPEAKDESIEKERSRDEEVGDKEKVGGEN 368
+ K+ K + +N K K + + K +S +++ E + K N
Sbjct: 117 EQSKKSKSSSETNPESQNSKTVSKNCSQKD-----KKDSKNSKKTNTEFLHTKN-----N 166
Query: 369 VKKKMKELKEAEPTTPTTNRPVRERKSVERLVESY------DRDASKEFQIEEGRGTPLK 422
KK +K K T+N P+ E S L + D S F R
Sbjct: 167 PKKDLKRSK-------TSNDPISEICSENSLNVDFLMLVGQSDDESINFDAWL-RNYSQN 218
Query: 423 NIPNVAFKLSRRKVDDTLKFLHTILFCRRGKAAVIKKNILRFSGFVWHENEE--KQMIKV 480
N N + K ++ DT KKN + S ++++ K KV
Sbjct: 219 NSKNYSLKYTKYTKKDT------------------KKNAKKSSDAESEDSKDAKKDSKKV 260
Query: 481 KEKFDKCNKEK-LLEFSDLLDVPVGNANTRKEDIIAKLIDFLVAPQVTKSVLLAEQEKSA 539
K+ K +K+K + + ++ D G++ ++D + K + +++K
Sbjct: 261 KKNVKKDDKKKDVKKDTESTDAESGDSKDERKD----------TKKDKKKLKKDDKKKDT 310
Query: 540 K---EKRIAKQGSTGSGTPTSRRSAKSRKKIEDSSIAEKKKTATDTESESEKDEENKEEN 596
K E + G SR K+ K + A+K +TD+ESE E E K+E
Sbjct: 311 KKYPESTDTESGDAKDARNDSRNLKKASKNDDKKKDAKKITFSTDSESELESKESQKDEK 370
Query: 597 EIDVSDKSEDEKPIKGKKHIA-----KQGSSRSGTASSRRSAKE 635
+ K++++K +K + +G S+ G ++ K+
Sbjct: 371 KDKKDSKTDNKKSVKNDEESTDADSEPKGDSKKGKKDEKKGKKD 414
Score = 50.1 bits (118), Expect = 2e-05
Identities = 98/463 (21%), Positives = 178/463 (38%), Gaps = 85/463 (18%)
Query: 212 KKAEGEELKEDKKVDAGDEIEEDKKDDNGFEDDKLSEETELSKEERESVEAKKPELDAMD 271
KKAE ++ K++K G +++D K G + E ++ VE K + D
Sbjct: 58 KKAEYKKSKDEK---GGTPLKKDSKKKGG--------SYATNPESKQIVEEKTKRQNEAD 106
Query: 272 EESILEGKDEGSEKEKSQKDREDDKDKVDNKSNEENIKVEKRLKKRGKGKVNGE------ 325
+ L+ E + +KS+ E + + ++K+ +N + + + K N E
Sbjct: 107 KTP-LKSSHENEQSKKSKSSSETNPESQNSKTVSKNCSQKDKKDSKNSKKTNTEFLHTKN 165
Query: 326 NVKKKMKELKKIED-IPE-AKDESIEKE------RSRDEEVG-DKEKVGGENVKKKMKEL 376
N KK +K K D I E + S+ + +S DE + D K L
Sbjct: 166 NPKKDLKRSKTSNDPISEICSENSLNVDFLMLVGQSDDESINFDAWLRNYSQNNSKNYSL 225
Query: 377 KEAEPTTPTTNRPVRERKSVERLVESYDRDASKEFQIEEGRGTPLKNIPNVAFKLSRRKV 436
K + T T + ++ E +DA K+ + + KN+ K
Sbjct: 226 KYTKYTKKDTKKNAKKSSDAE---SEDSKDAKKDSKKVK------KNV----------KK 266
Query: 437 DDTLKFLHTILFCRRGKAAVIKKNILRFSGFVWHENEEKQMIKVKEKFDKCNKEK-LLEF 495
DD K + ++ K +E K K K+K K +K+K ++
Sbjct: 267 DDKKKDVKKDTESTDAESGDSK-------------DERKDTKKDKKKLKKDDKKKDTKKY 313
Query: 496 SDLLDVPVGNANTRKEDIIAKLIDFLVAPQVTKSVLLAEQEKSAKEKRIAKQGSTGSGTP 555
+ D G+A + D S L + K+ +K+ AK+ + + +
Sbjct: 314 PESTDTESGDAKDARND----------------SRNLKKASKNDDKKKDAKKITFSTDSE 357
Query: 556 T---SRRSAKSRKKIEDSSIAEKKKTATDTESESEKDEENKEENEIDVSDKSEDEKPIKG 612
+ S+ S K KK + S + KK+ + E ++ D E K D +DEK KG
Sbjct: 358 SELESKESQKDEKKDKKDSKTDNKKSVKNDEESTDADSEPKG----DSKKGKKDEK--KG 411
Query: 613 KKHIAKQGSSRSGTASSRRSAKE*NIFQKERIRCTKQSKESNR 655
KK K + ++ + E ++ K+ + +K+ K S +
Sbjct: 412 KKDSKKDDKKKDAKKNAESTEMESDLELKKDKKHSKEKKGSKK 454
>TRDN_CANFA (P82179) Triadin
Length = 700
Score = 87.8 bits (216), Expect = 1e-16
Identities = 145/626 (23%), Positives = 264/626 (42%), Gaps = 77/626 (12%)
Query: 21 KIFEDNAVQDLKEDGIKAME--VDKKAD---GEEVLEMDKLADDGDVVTENAIKAGDGEG 75
K F +++ + D +K + V++ D G L D ++ DGD ++ + D +G
Sbjct: 73 KNFSASSLSKIGSDPLKLVHDAVEETTDWVYGFFSLLSDIISSDGDEDDDDGDEDTD-KG 131
Query: 76 IKEDEKVNEGKEIKEDKQADEGEELK------EDKKDNGGEERKEDKKVDVGQEVKEDKK 129
E+ + + + KE + +E E K +K+ E+ K +KK +++++ +K
Sbjct: 132 EIEEPPLKQKEIHKEKAEKEEKPERKILAKVAHREKEKVKEKEKSEKKATHKEKIEKKEK 191
Query: 130 VNEGGDIKEEKKADEGEKLKEDKKDDAAVKIKED-KKVNEGEELKEEKKADEGEK----L 184
KEE+KA EK+K++ K K+K KV E ++ + K EG++
Sbjct: 192 PETKTMAKEERKAKTEEKIKKEVKGGKQEKVKPTAAKVKEVQKTPPKAKEKEGKETAAVA 251
Query: 185 KEDKKDD-AGVEIIEDKKVNEGEELEEEKKAEGEEL---KEDKKVDAGDEIEEDKKDDNG 240
K ++KD A + D V+ G+ + A L + + A +E ++++
Sbjct: 252 KHEQKDQYAFCRYMIDMFVH-GDLRPGQSPALPPPLPTVQASRPTPASPTLEGKEEEEKK 310
Query: 241 FEDDKLSEETELSKEERESVEAKKPELDAMDEESILEGK----DEGSEKEKSQKDREDDK 296
+ K++ ET+ K+E+E V+ K + A+D E GK +G+ K +Q + D+
Sbjct: 311 KAEKKVTSETK--KKEKEDVKKKSDKDTAIDVEKKEPGKAPETKQGTIKVVAQAAAKKDE 368
Query: 297 DKVDNKSNEENIKVEKRLKKRGKGKVNGENVKKKMKELKKIEDIPEAKDESIEKERSRDE 356
K D+K + ++ + KK+ K E + K KK P K + ER+
Sbjct: 369 KKEDSKKTKTPVEEHPKGKKQEK----KEKYVEPAKSSKKEHSAPSEKQVKAKTERA--- 421
Query: 357 EVGDKEKVGGENVKKKMKELKEAEPTTPTTNRPVRERKSVERLVESYDRDASKEFQIEEG 416
KE+ + KK + KE E TT T + +R+ KS + S D KE +I++
Sbjct: 422 ----KEETSAASTKKAVPGKKE-EKTTKTVEQEIRKEKSGKTSTASKD----KEPEIKKD 472
Query: 417 RGTP-----LKNIPNVAFKLSRRKVDDTLKFLHTILFCRRGKAAVIKKNILRFSGFVWHE 471
P +K P + K + +K K A +++I + V H
Sbjct: 473 EKMPKADKEVKPKPPQSQVKKEEKSESQVK-----------KEAKPEQDIAKPEKTVSHG 521
Query: 472 NEEKQMIKVKEKFDKCNKEKLLEFSDLLDVPVGNANTRKEDIIAKLID-----FLVAPQV 526
E++++K + +K EK ++ P A ++++ D P+V
Sbjct: 522 KPEEKVVKQVKATEKAAIEKTVK-----PKPAKKAEHQEKESPTIKTDKPKPTSKETPEV 576
Query: 527 TKS--VLLAEQEKSAKEKRIAKQGSTGSGTPTSRRSAKSRKKIEDSSIAEKKKTATDTES 584
T+S + + EK +KEK K T + S +S + A + + S
Sbjct: 577 TESGKKKIEKSEKESKEKAEMKH-LKEEKVSTRKESLQSHNVTKAEKPARVSREDLEDVS 635
Query: 585 ESEKDEENKEENEIDVSDKSEDEKPI 610
S+K +E E DVS + PI
Sbjct: 636 ASKKAKEEAE----DVSSTKRQKSPI 657
Score = 86.7 bits (213), Expect = 2e-16
Identities = 126/604 (20%), Positives = 235/604 (38%), Gaps = 128/604 (21%)
Query: 91 DKQADEGE------ELKEDKKDNGGEERKEDKKVDVGQEVKEDKKVNEGGDIKEEKKADE 144
D+ D+GE + KE K+ +E K ++K+ +E +KV E K EKKA
Sbjct: 125 DEDTDKGEIEEPPLKQKEIHKEKAEKEEKPERKILAKVAHREKEKVKEKE--KSEKKATH 182
Query: 145 GEKLKEDKKDDAAVKIKEDKKVNEGEELKEEKKADEGEKLKEDKKDDAGVEIIEDK-KVN 203
EK+++ +K + KE++K E++K+E K + EK+K V+ K K
Sbjct: 183 KEKIEKKEKPETKTMAKEERKAKTEEKIKKEVKGGKQEKVKPTAAKVKEVQKTPPKAKEK 242
Query: 204 EGEELEEEKKAEGEE-------------------------------LKEDKKVDAGDEIE 232
EG+E K E ++ ++ + A +E
Sbjct: 243 EGKETAAVAKHEQKDQYAFCRYMIDMFVHGDLRPGQSPALPPPLPTVQASRPTPASPTLE 302
Query: 233 EDKKDDNGFEDDKLSEETELSKEERESVEAKKPELDAMDEESILEGK----DEGSEKEKS 288
++++ + K++ ET+ K+E+E V+ K + A+D E GK +G+ K +
Sbjct: 303 GKEEEEKKKAEKKVTSETK--KKEKEDVKKKSDKDTAIDVEKKEPGKAPETKQGTIKVVA 360
Query: 289 QKDREDDKDKVDNKSNEENIKVEKRLKKRGKGKVNGENVKKKMKELKKIEDIPEAKDESI 348
Q + D+ K D+K + ++ + KK+ K + E K KE P K
Sbjct: 361 QAAAKKDEKKEDSKKTKTPVEEHPKGKKQEKKEKYVEPAKSSKKE----HSAPSEKQVKA 416
Query: 349 EKERSRDEEVGDKEKVGGENVKKKMKELKEAEPTTPTTNRPVRERKSVERLVESYDRDAS 408
+ ER+ KE+ + KK + KE E TT T + +R+ KS + S D
Sbjct: 417 KTERA-------KEETSAASTKKAVPGKKE-EKTTKTVEQEIRKEKSGKTSTASKD---- 464
Query: 409 KEFQIEEGRGTPLKNIPNVAFKLSRRKVDDTLKFLHTILFCRRGKAAVIKKNILRFSGFV 468
KE +I++ P K D +K
Sbjct: 465 KEPEIKKDEKMP--------------KADKEVK--------------------------- 483
Query: 469 WHENEEKQMIKVKEKFDKCNKEKLLEFSDLLDVPVGNANTRKEDIIAKLIDFLVAPQVTK 528
+ +K +EK + K++ D+ ++ + E+ + K + + K
Sbjct: 484 --PKPPQSQVKKEEKSESQVKKEAKPEQDIAKPEKTVSHGKPEEKVVKQVKATEKAAIEK 541
Query: 529 SVLLAEQEKSAKEKRIAKQGSTGSGTPTSRRSAKSRKKIEDSSIAEKKKTATDTESESEK 588
+V +K+ +++ + T PTS K+T TES +K
Sbjct: 542 TVKPKPAKKAEHQEKESPTIKTDKPKPTS------------------KETPEVTESGKKK 583
Query: 589 DEENKEENEIDVSDKSEDEKPIKGKKHIAKQGSSRSGTASSRRSAKE*NIFQKERIRCTK 648
E++++E++ K E+ + +K + + +R S ++ E + +K
Sbjct: 584 IEKSEKESKEKAEMKHLKEEKVSTRKESLQSHNVTKAEKPARVSRED-----LEDVSASK 638
Query: 649 QSKE 652
++KE
Sbjct: 639 KAKE 642
Score = 64.7 bits (156), Expect = 9e-10
Identities = 101/453 (22%), Positives = 188/453 (41%), Gaps = 45/453 (9%)
Query: 234 DKKDDNGFEDDKLSEETELSKEERESVEAKKPELDAMDEESIL-----EGKDEGSEKEKS 288
D+ DD+G ED E E +++E + +K E + E IL K++ EKEKS
Sbjct: 118 DEDDDDGDEDTDKGEIEEPPLKQKE-IHKEKAEKEEKPERKILAKVAHREKEKVKEKEKS 176
Query: 289 QK-----DREDDKDKVDNKS---NEENIKVEKRLKKRGKGKVNGENVKKKMKELKKIEDI 340
+K ++ + K+K + K+ E K E+++KK KG E VK ++K+++
Sbjct: 177 EKKATHKEKIEKKEKPETKTMAKEERKAKTEEKIKKEVKGGKQ-EKVKPTAAKVKEVQKT 235
Query: 341 PEAKDESIEKERSRDEEVGDKEK-----------VGGENVKKKMKELKEAEPTT----PT 385
P E KE + + K++ V G+ + L PT PT
Sbjct: 236 PPKAKEKEGKETAAVAKHEQKDQYAFCRYMIDMFVHGDLRPGQSPALPPPLPTVQASRPT 295
Query: 386 TNRPVRERKSVERLVESYDRDASKEFQIEEGRGTPLKNIPNVAFKLSRR---KVDDTLKF 442
P E K E ++ ++ + E + +E K+ + A + ++ K +T +
Sbjct: 296 PASPTLEGKEEEEKKKA-EKKVTSETKKKEKEDVKKKSDKDTAIDVEKKEPGKAPETKQG 354
Query: 443 LHTILFCRRGKAAVIKKNILRFSGFVWHENEEKQMIKVKEKFDKCNKEKLLEFSDLLDVP 502
++ K K++ + V + K+ K KEK+ + K E S +
Sbjct: 355 TIKVVAQAAAKKDEKKEDSKKTKTPVEEHPKGKKQEK-KEKYVEPAKSSKKEHSAPSEKQ 413
Query: 503 VGNANTRKEDIIAKLIDFLVAPQVTKSVLLAEQEKSAK--EKRIAKQGSTGSGTPTSRRS 560
V R ++ + A K+V ++EK+ K E+ I K+ S G + S+
Sbjct: 414 VKAKTERAKEETS-------AASTKKAVPGKKEEKTTKTVEQEIRKEKS-GKTSTASKDK 465
Query: 561 AKSRKKIEDSSIAEKKKTATDTESESEKDEENKEENEIDVSDKSEDEKPIKGKKHIAKQG 620
KK E A+K+ +S+ +K+E+++ + + + + + KP K H +
Sbjct: 466 EPEIKKDEKMPKADKEVKPKPPQSQVKKEEKSESQVKKEAKPEQDIAKPEKTVSHGKPEE 525
Query: 621 SSRSGTASSRRSAKE*NIFQKERIRCTKQSKES 653
++ ++A E + K + Q KES
Sbjct: 526 KVVKQVKATEKAAIEKTVKPKPAKKAEHQEKES 558
>IE68_SHV21 (Q01042) Immediate-early protein
Length = 407
Score = 87.4 bits (215), Expect = 1e-16
Identities = 68/263 (25%), Positives = 131/263 (48%), Gaps = 10/263 (3%)
Query: 59 DGDVVTENAIKAGDGEGIKEDEKVNEGKEIKEDKQADEGEELKEDKKDNGGEERKEDKKV 118
D D+ T + +A E + +E EG+E + GEE +E + GE R+E ++
Sbjct: 45 DDDINTTHQQQAALTEEQRREEVEEEGEERER-----RGEEEREGEGGEEGEGREEAEEE 99
Query: 119 DVGQEVKEDKKVNEGGDIKEEKKADEGEKLKEDKKDDAAVKIK-EDKKVNEGEELKEEKK 177
+ ++ E+++ E + EE++A+E E +E+ +++ A + + E+ + E EE +EE +
Sbjct: 100 EAEEKEAEEEEAEEAEEEAEEEEAEEAEAEEEEAEEEEAEEEEAEEAEEEEAEEAEEEAE 159
Query: 178 ADEGEKLKEDKKDDAGVEIIEDKKVNEGEELEEEKKAE-GEELKEDKKVDAGDEIEEDKK 236
+E E+ E++ ++A E E++ E EE EE ++AE EE E+ + +A + EE ++
Sbjct: 160 EEEAEEEAEEEAEEA--EEAEEEAEEEAEEAEEAEEAEEAEEEAEEAEEEAEEAEEEAEE 217
Query: 237 DDNGFEDDKLSEETELSKEERESVEAKKPELDAMDEESILEGKDEGSEKEKSQKDREDDK 296
+ E ++ EE E ++EE E P L G + K + +
Sbjct: 218 AEEAEEAEEAEEEAEEAEEEEEEAGPSTPRLPHYKVVGQKPSTQPGGVPKLCLKMQPQHR 277
Query: 297 DKVDNKSNEENIKVEKRLKKRGK 319
++ K + + KV K+ + R K
Sbjct: 278 SRLP-KGKQSHDKVPKKYQARNK 299
Score = 85.5 bits (210), Expect = 5e-16
Identities = 56/213 (26%), Positives = 117/213 (54%), Gaps = 14/213 (6%)
Query: 147 KLKEDKKDDAAVKIKEDKKVNEGEELKE-EKKADEGEKLKEDKKDDAGVEIIEDKKVNEG 205
KLK DD ++ + E + +E E++ +E E+ E++++ G E EG
Sbjct: 39 KLKPQGDDDINTTHQQQAALTEEQRREEVEEEGEERERRGEEEREGEGGE------EGEG 92
Query: 206 EELEEEKKAEGEELKEDKKVDAGDEIEEDKKDDNGFEDDKLSEE--TELSKEERESVEAK 263
E EE++AE +E +E++ +A +E EE++ ++ E+++ EE E EE E EA+
Sbjct: 93 REEAEEEEAEEKEAEEEEAEEAEEEAEEEEAEEAEAEEEEAEEEEAEEEEAEEAEEEEAE 152
Query: 264 KPELDAMDEESILEGKDEGSEKEKSQKDREDDKDKVDNKSNEENIKVEKRLKKRGKGKVN 323
+ E +A +EE+ E ++E E E+++++ E++ ++ EE + E+ ++ + +
Sbjct: 153 EAEEEAEEEEAEEEAEEEAEEAEEAEEEAEEEAEEA-----EEAEEAEEAEEEAEEAEEE 207
Query: 324 GENVKKKMKELKKIEDIPEAKDESIEKERSRDE 356
E +++ +E ++ E+ EA++E+ E E +E
Sbjct: 208 AEEAEEEAEEAEEAEEAEEAEEEAEEAEEEEEE 240
Score = 77.8 bits (190), Expect = 1e-13
Identities = 57/219 (26%), Positives = 112/219 (51%), Gaps = 28/219 (12%)
Query: 183 KLKEDKKDDAGVE------IIEDKKVNEGEELEEEKKAEGEELKEDKKVDAGD---EIEE 233
KLK DD + E+++ E EE EE++ GEE +E + + G+ E EE
Sbjct: 39 KLKPQGDDDINTTHQQQAALTEEQRREEVEEEGEERERRGEEEREGEGGEEGEGREEAEE 98
Query: 234 DKKDDNGFEDDKLSEETELSKEERESVEAKKPELDAMDEESILEGKDEGSEKEKSQKDRE 293
++ ++ E+++ +EE E EE E+ EA+ E +A +EE+ E +E E+E + + E
Sbjct: 99 EEAEEKEAEEEE-AEEAEEEAEEEEAEEAEAEEEEAEEEEAEEEEAEEAEEEEAEEAEEE 157
Query: 294 DDKDKVDNKSNEENIKVEKRLKKRGKGKVNGENVKKKMKELKKIEDIPEAKDESIEKERS 353
++++ + ++ EE + E+ E +++ +E ++ E+ EA++E+ E E
Sbjct: 158 AEEEEAEEEAEEEAEEAEEA----------EEEAEEEAEEAEEAEEAEEAEEEAEEAEEE 207
Query: 354 RDE--------EVGDKEKVGGENVKKKMKELKEAEPTTP 384
+E E ++ + E ++ +E +EA P+TP
Sbjct: 208 AEEAEEEAEEAEEAEEAEEAEEEAEEAEEEEEEAGPSTP 246
Score = 65.9 bits (159), Expect = 4e-10
Identities = 47/215 (21%), Positives = 111/215 (50%), Gaps = 5/215 (2%)
Query: 5 HLDDSSEKKDLEPKGGK-IFEDNAVQDLKEDGIKAMEVDKKADGEEVLEMDKLADDGDVV 63
++ ++ L+P+G I + Q + + EV+++ + E ++ +G
Sbjct: 30 YVSPRKRRRKLKPQGDDDINTTHQQQAALTEEQRREEVEEEGEERERRGEEEREGEGGEE 89
Query: 64 TENAIKAGDGEGIKEDEKVNEGKEIKEDKQADEGEELKEDKKDNGGEERKEDKKVDVGQE 123
E +A + E +++ + E +E +E+ + +E EE E +++ EE E+++ + +E
Sbjct: 90 GEGREEAEEEEAEEKEAEEEEAEEAEEEAEEEEAEEA-EAEEEEAEEEEAEEEEAEEAEE 148
Query: 124 VKEDKKVNEGGDIKEEKKADEGEKLKEDKKDDAAVKIKEDKKVNEGEELKEEKKA--DEG 181
+ ++ E + + E++A+E + E+ +++A + +E ++ E EE +EE + +E
Sbjct: 149 EEAEEAEEEAEEEEAEEEAEEEAEEAEEAEEEAEEEAEEAEEAEEAEEAEEEAEEAEEEA 208
Query: 182 EKLKEDKKDDAGVEIIEDKKVNEGEELEEEKKAEG 216
E+ +E+ ++ E E+ + E EE EEE++ G
Sbjct: 209 EEAEEEAEEAEEAEEAEEAE-EEAEEAEEEEEEAG 242
Score = 47.8 bits (112), Expect = 1e-04
Identities = 33/146 (22%), Positives = 74/146 (50%), Gaps = 1/146 (0%)
Query: 7 DDSSEKKDLEPKGGKIFEDNAVQDLKEDGIKAMEVDKKADGEEVLEMDKLADDGDVVTEN 66
++ +E+ + E + + E A ++ E+ E ++A+ EE E ++ A++ + E
Sbjct: 108 EEEAEEAEEEAEEEEAEEAEAEEEEAEEEEAEEEEAEEAEEEEAEEAEEEAEEEEAEEEA 167
Query: 67 AIKAGDGEGIKEDEKVNEGKEIKEDKQADEGEELKEDKKDNGGEERKEDKKVDVGQEVKE 126
+A + E E+E E +E +E ++A+E EE E+ ++ E +E ++ + +E +E
Sbjct: 168 EEEAEEAEEA-EEEAEEEAEEAEEAEEAEEAEEEAEEAEEEAEEAEEEAEEAEEAEEAEE 226
Query: 127 DKKVNEGGDIKEEKKADEGEKLKEDK 152
++ E + +EE+ +L K
Sbjct: 227 AEEEAEEAEEEEEEAGPSTPRLPHYK 252
Score = 39.7 bits (91), Expect = 0.032
Identities = 21/76 (27%), Positives = 38/76 (49%), Gaps = 1/76 (1%)
Query: 534 EQEKSAKEKRIAKQGSTGSGTPTSRRSAKSRKKIEDSSIAEKKKTATDTES-ESEKDEEN 592
E+E+ +E+R + G G G + K+ E+ E ++ A + E+ E+E +EE
Sbjct: 73 ERERRGEEEREGEGGEEGEGREEAEEEEAEEKEAEEEEAEEAEEEAEEEEAEEAEAEEEE 132
Query: 593 KEENEIDVSDKSEDEK 608
EE E + + E E+
Sbjct: 133 AEEEEAEEEEAEEAEE 148
Score = 37.7 bits (86), Expect = 0.12
Identities = 28/127 (22%), Positives = 63/127 (49%), Gaps = 6/127 (4%)
Query: 8 DSSEKKDLEPKGGKIFEDNAVQDLKEDGIKAMEVDKKADGEEVLEMDKLADDGDVVTENA 67
+ +E+++ E + E+ A ++ +E+ +A E +++A EE E + A++ + E A
Sbjct: 144 EEAEEEEAEEAEEEAEEEEAEEEAEEEAEEAEEAEEEA--EEEAEEAEEAEEAEEAEEEA 201
Query: 68 IKAGDGEGIKEDEKVNEGKEIKEDKQADEGEELKEDKKDNGGEERKEDKKVDVGQEVKED 127
+A + + +E E +E +E ++A+E EE E+ ++ E ++ + V +
Sbjct: 202 EEAEE----EAEEAEEEAEEAEEAEEAEEAEEEAEEAEEEEEEAGPSTPRLPHYKVVGQK 257
Query: 128 KKVNEGG 134
GG
Sbjct: 258 PSTQPGG 264
Score = 33.5 bits (75), Expect = 2.3
Identities = 29/110 (26%), Positives = 50/110 (45%), Gaps = 6/110 (5%)
Query: 309 KVEKRLKKRGKGKVNGENVKKKMKELKKIEDIPEAKDESIEKERSRDEE---VGDKEKVG 365
K ++LK +G +N ++ L + + E ++E E+ER +EE G +E G
Sbjct: 35 KRRRKLKPQGDDDIN--TTHQQQAALTEEQRREEVEEEGEERERRGEEEREGEGGEEGEG 92
Query: 366 GENVKKKMKELKEAEPTTPTTNRPVRERKSVERLVESYDRDASKEFQIEE 415
E +++ E KEAE E + E E+ + +A +E EE
Sbjct: 93 REEAEEEEAEEKEAEEEEAEEAEEEAEEEEAEE-AEAEEEEAEEEEAEEE 141
Score = 31.6 bits (70), Expect = 8.6
Identities = 19/101 (18%), Positives = 47/101 (45%), Gaps = 3/101 (2%)
Query: 535 QEKSAKEKRIAKQGSTGSGTPTSRRSAKSRKKIEDSSIAEKKKTATDTESESEKDEENKE 594
+EK A+E+ + A+ + E+ + E+ + A + E+E ++E +E
Sbjct: 102 EEKEAEEEEAEEAEEEAEEEEAEEAEAEEEEAEEEEAEEEEAEEAEEEEAEEAEEEAEEE 161
Query: 595 ENEIDVSDKSEDEKPIKGKKHIAKQGSSRSGTASSRRSAKE 635
E E + +++E+ + + + A++ + + A A+E
Sbjct: 162 EAEEEAEEEAEEAEEAEEE---AEEEAEEAEEAEEAEEAEE 199
>FUTS_DROME (Q9W596) Microtubule-associated protein futsch
Length = 5412
Score = 87.0 bits (214), Expect = 2e-16
Identities = 154/674 (22%), Positives = 276/674 (40%), Gaps = 119/674 (17%)
Query: 80 EKVNEGKEIKEDKQADEGEELKEDKKDNGGEERKEDKKVDVGQEVKEDKKVNEGGDIKEE 139
E V +GK K+A + E+ KD+ +E KE + + Q ++ G IK+E
Sbjct: 3244 ESVKDGKSPVASKEASRPASVAENAKDSA-DESKEQRPESLPQ--------SKAGSIKDE 3294
Query: 140 KKA----DEGEKLKEDKKDDAAVK--------------IKEDKKVNEGEELKEE-----K 176
K DE EK KE+ + ++ + + E K +E E+ KEE K
Sbjct: 3295 KSPLASKDEAEKSKEESRRESVAEQFPLVSKEVSRPASVAESVK-DEAEKSKEESPLMSK 3353
Query: 177 KA-----------DEGEKLKEDKKDDAGVEI--IEDKKVNEGEELEEEKKAEGEELKEDK 223
+A DE EK KE+ + ++ E + K+ + + E K E ++ KE+
Sbjct: 3354 EASRPASVAGSVKDEAEKSKEESRRESVAEKSPLPSKEASRPASVAESVKDEADKSKEES 3413
Query: 224 KVDAGDE---IEEDKKDDNGFEDDKLSEETELSKEE--RESVEAKKP--ELDAMDEESIL 276
+ ++G E + + + + +E E SKEE RESV K P +A S+
Sbjct: 3414 RRESGAEKSPLASKEASRPASVAESIKDEAEKSKEESRRESVAEKSPLPSKEASRPTSVA 3473
Query: 277 EG-KDEGSE-KEKSQKDREDDKDKVDNKSNEENIKVEKRLK---KRGKGKVNGENVKKKM 331
E KDE + KE+S++D +K + +K V + ++ ++ K + E+V +K
Sbjct: 3474 ESVKDEAEKSKEESRRDSVAEKSPLASKEASRPASVAESVQDEAEKSKEESRRESVAEKS 3533
Query: 332 KELKKIEDIPEAKDESIE------KERSRDEEVGDKEKVGG----------ENVKKKMKE 375
K P + ESI+ KE SR E V +K + E+VK + ++
Sbjct: 3534 PLASKEASRPASVAESIKDEAEKSKEESRRESVAEKSPLASKEASRPTSVAESVKDEAEK 3593
Query: 376 LKEAEPTTPTTNRPVRERKSVER---LVESYDRDASKEFQIEEGRGTPLKNIPNVAFKLS 432
KE + K R + ES +A K + E R + + P + + S
Sbjct: 3594 SKEESSRDSVAEKSPLASKEASRPASVAESVQDEAEKSKE-ESRRESVAEKSPLASKEAS 3652
Query: 433 R-RKVDDTLKFLHTILFCRRGKAAVIKKNILRFSGFVWHENEEKQMI--KVKEKFDKCNK 489
R V +++K + K ++++ S E + VK++ +K +
Sbjct: 3653 RPASVAESVKD-----DAEKSKEESRRESVAEKSPLASKEASRPASVAESVKDEAEKSKE 3707
Query: 490 EKLLEFSDLLDVPVGNANTRKEDIIAKLIDFLVAPQVTKSVLLAEQEKSAKEKRIA-KQG 548
E E S P+ + + +A+ V + KS + +E A++ +A K+
Sbjct: 3708 ESRRE-SVAEKSPLPSKEASRPTSVAES----VKDEAEKSKEESRRESVAEKSSLASKKA 3762
Query: 549 STGSGTPTSRR--SAKSRKKIEDSSIAEKKKTATDTES------ESEKDEENKEENEI-- 598
S + S + + KS+++ S+AEK A+ S ES KDE K + E
Sbjct: 3763 SRPASVAESVKDEAEKSKEESRRESVAEKSPLASKEASRPASVAESVKDEAEKSKEESRR 3822
Query: 599 -DVSDKS-----EDEKPI-----------KGKKHIAKQGSSRSGTASSRRSAKE*NIFQK 641
V++KS E +P K K+ ++ + +S +++ ++ +
Sbjct: 3823 ESVAEKSPLPSKEASRPTSVAESVKDEADKSKEESRRESGAEKSPLASMEASRPTSVAES 3882
Query: 642 ERIRCTKQSKESNR 655
+ K +ES R
Sbjct: 3883 VKDETEKSKEESRR 3896
Score = 86.7 bits (213), Expect = 2e-16
Identities = 149/703 (21%), Positives = 294/703 (41%), Gaps = 108/703 (15%)
Query: 4 NHLDDSSEKKDLEP------KGGKIFEDNAVQDLKEDGIKAMEVDKKADGEEVLEMDKLA 57
N D + E K+ P K G I ++ + K++ K+ E ++ E V E L
Sbjct: 3267 NAKDSADESKEQRPESLPQSKAGSIKDEKSPLASKDEAEKSKEESRR---ESVAEQFPL- 3322
Query: 58 DDGDVVTENAIKAGDGEGIKEDEKVNEGKEIKEDKQADEGEELKEDKKDNGGEERKEDKK 117
V E + A E +K++ + ++ + K+A + KD + ++E ++
Sbjct: 3323 ----VSKEVSRPASVAESVKDEAEKSKEESPLMSKEASRPASVAGSVKDEAEKSKEESRR 3378
Query: 118 VDVGQEVK-EDKKVNEGGDIKEEKKADEGEKLKEDKKDDAAVKIKE--DKKVNEGEELKE 174
V ++ K+ + + E K DE +K KE+ + ++ + K+ + + E
Sbjct: 3379 ESVAEKSPLPSKEASRPASVAESVK-DEADKSKEESRRESGAEKSPLASKEASRPASVAE 3437
Query: 175 EKKADEGEKLKEDKKDDAGVEI--IEDKKVNEGEELEEEKKAEGEELKEDKKVDAGDE-- 230
K DE EK KE+ + ++ E + K+ + + E K E E+ KE+ + D+ E
Sbjct: 3438 SIK-DEAEKSKEESRRESVAEKSPLPSKEASRPTSVAESVKDEAEKSKEESRRDSVAEKS 3496
Query: 231 -IEEDKKDDNGFEDDKLSEETELSKEE--RESVEAKKP--ELDAMDEESILEGKDEGSEK 285
+ + + + +E E SKEE RESV K P +A S+ E + +EK
Sbjct: 3497 PLASKEASRPASVAESVQDEAEKSKEESRRESVAEKSPLASKEASRPASVAESIKDEAEK 3556
Query: 286 EKSQKDRED--DKDKVDNKSNEENIKVEKRLK---KRGKGKVNGENVKKKMKELKKIEDI 340
K + RE +K + +K V + +K ++ K + + ++V +K K
Sbjct: 3557 SKEESRRESVAEKSPLASKEASRPTSVAESVKDEAEKSKEESSRDSVAEKSPLASKEASR 3616
Query: 341 PEAKDESIEKERSRDEEVGDKEKVGGENVKKKMKELKEAEPTTPTTNRPVRERKSVERLV 400
P + ES++ E + +E +E V +K KEA +RP +SV+
Sbjct: 3617 PASVAESVQDEAEKSKEESRRESVA----EKSPLASKEA-------SRPASVAESVKD-- 3663
Query: 401 ESYDRDASKEFQIEEGRGTPLKNIPNVAFKLSR-RKVDDTLKFLHTILFCRRGKAAVIKK 459
D + SKE E R + + P + + SR V +++K + K ++
Sbjct: 3664 ---DAEKSKE---ESRRESVAEKSPLASKEASRPASVAESVKDE-----AEKSKEESRRE 3712
Query: 460 NILRFSGFVWHENEEKQMI--KVKEKFDKCNKEKLLEFSDLLDVPVGNANTRKEDIIAKL 517
++ S E + VK++ +K +E +R+E + K
Sbjct: 3713 SVAEKSPLPSKEASRPTSVAESVKDEAEKSKEE-----------------SRRESVAEK- 3754
Query: 518 IDFLVAPQVTKSVLLAE--QEKSAKEKRIAKQGSTGSGTPTSRRSA-------------- 561
L + + ++ +AE ++++ K K +++ S +P + + A
Sbjct: 3755 -SSLASKKASRPASVAESVKDEAEKSKEESRRESVAEKSPLASKEASRPASVAESVKDEA 3813
Query: 562 -KSRKKIEDSSIAEK-----KKTATDTE-SESEKDE--ENKEENEIDVSDKSEDEKPIKG 612
KS+++ S+AEK K+ + T +ES KDE ++KEE+ + + ++
Sbjct: 3814 EKSKEESRRESVAEKSPLPSKEASRPTSVAESVKDEADKSKEESRRESGAEKSPLASMEA 3873
Query: 613 KKHIAKQGSSRSGTASSRRSAKE*NIFQKERIRCTKQSKESNR 655
+ + S + T S+ ++ ++ +K + SKE++R
Sbjct: 3874 SRPTSVAESVKDETEKSKEESRRESVTEKSPL----PSKEASR 3912
Score = 84.7 bits (208), Expect = 9e-16
Identities = 130/659 (19%), Positives = 254/659 (37%), Gaps = 75/659 (11%)
Query: 53 MDKLADDGDVVTENAIKAGDGEGIKEDEKVNEGKEIKEDKQADEGEELKEDKKDNGGEER 112
+ L D+GD T + D + + K + ++A E E KD +
Sbjct: 3183 LGSLKDEGDKTTSRRVSVADS--------IKDEKSLLVSQEASRPESEAESLKDAAAPSQ 3234
Query: 113 KEDKKVDVGQEVKEDKKVNEGGDIKEEKKADEGEKLKEDKKDDAAVKIKEDKKVNEGEEL 172
+ + V + VK+ K + E K D D++ + E ++ +
Sbjct: 3235 ETSRPESVTESVKDGKSPVASKEASRPASVAENAK---DSADESKEQRPESLPQSKAGSI 3291
Query: 173 KEEKKA----DEGEKLKEDKKDDAGVE-------------IIEDKKVNEGEELEEEKKAE 215
K+EK DE EK KE+ + ++ E + + +E E+ +EE
Sbjct: 3292 KDEKSPLASKDEAEKSKEESRRESVAEQFPLVSKEVSRPASVAESVKDEAEKSKEESPLM 3351
Query: 216 GEELKEDKKVDAGDEIEEDKKDDNGFEDDKLSEETELSKEERES----VEAKKPELDAMD 271
+E V AG +E +K + ++E++ L +E E+ K E D
Sbjct: 3352 SKEASRPASV-AGSVKDEAEKSKEESRRESVAEKSPLPSKEASRPASVAESVKDEADKSK 3410
Query: 272 EESILEGKDEGSEKEKSQKDR--------EDDKDKVDNKSNEENIKVEKRL--KKRGKGK 321
EES E E S + R +D+ +K +S E++ + L K+ +
Sbjct: 3411 EESRRESGAEKSPLASKEASRPASVAESIKDEAEKSKEESRRESVAEKSPLPSKEASRPT 3470
Query: 322 VNGENVK---KKMKELKKIEDIPEAKDESIEKERSRDEEVGDKEKVGGENVKKKMKELKE 378
E+VK +K KE + + + E K KE SR V + + E K++ +
Sbjct: 3471 SVAESVKDEAEKSKEESRRDSVAE-KSPLASKEASRPASVAESVQDEAEKSKEESRRESV 3529
Query: 379 AEPT---TPTTNRPVRERKSVERLVESYDRDASKEFQIEE--------GRGTPL-KNIPN 426
AE + + +RP +S++ E ++ +E E+ R T + +++ +
Sbjct: 3530 AEKSPLASKEASRPASVAESIKDEAEKSKEESRRESVAEKSPLASKEASRPTSVAESVKD 3589
Query: 427 VAFKLSRRKVDDTLKFLHTILFCRRGKAAVIKKNILRFSGFVWHENEEKQMIKVKEKFDK 486
A K D++ + + A + +++ EE + V EK
Sbjct: 3590 EAEKSKEESSRDSVAEKSPLASKEASRPASVAESV---QDEAEKSKEESRRESVAEKSPL 3646
Query: 487 CNKE----KLLEFSDLLDVPVGNANTRKEDIIAKLIDFLVAPQVTKSVLLAE--QEKSAK 540
+KE + S D +R+E + K L + + ++ +AE ++++ K
Sbjct: 3647 ASKEASRPASVAESVKDDAEKSKEESRRESVAEK--SPLASKEASRPASVAESVKDEAEK 3704
Query: 541 EKRIAKQGSTGSGTPTSRRSAKSRKKIEDS--SIAEKKKTATDTESESEKDE--ENKEEN 596
K +++ S +P + A + +S AEK K + ES +EK K
Sbjct: 3705 SKEESRRESVAEKSPLPSKEASRPTSVAESVKDEAEKSKEESRRESVAEKSSLASKKASR 3764
Query: 597 EIDVSDKSEDEKPIKGKKHIAKQGSSRSGTASSRRSAKE*NIFQKERIRCTKQSKESNR 655
V++ +DE K K+ ++ + +S+ +++ ++ + + K +ES R
Sbjct: 3765 PASVAESVKDEAE-KSKEESRRESVAEKSPLASKEASRPASVAESVKDEAEKSKEESRR 3822
Score = 79.7 bits (195), Expect = 3e-14
Identities = 107/472 (22%), Positives = 193/472 (40%), Gaps = 56/472 (11%)
Query: 2 LGNHLDDSSEKKDLEPKGGKIFEDNAVQDLKEDGIKAMEVDKKADGEEVL---------- 51
+G+ D+S K EP + +D A Q +E A + DG + L
Sbjct: 1874 VGSMKDESMSK---EPSRRESVKDGAAQS-RETSRPASVAESAKDGADDLKELSRPESTT 1929
Query: 52 ---EMDKLADD-GDVVTENAIK-AGDGEGIKEDEKVNEGKEIKED---------KQADEG 97
E + D+ + +E A + A E +K++ + ++ + +E K+A
Sbjct: 1930 QSKEAGSIKDEKSPLASEEASRPASVAESVKDEAEKSKEESRRESVAEKSPLPSKEASRP 1989
Query: 98 EELKEDKKDNGGEERKEDKKVDVGQEVK-EDKKVNEGGDIKEEKKADEGEKLKED-KKDD 155
+ E KD + ++E ++ V ++ K+ + + E K DE EK KE+ +++
Sbjct: 1990 ASVAESIKDEAEKSKEESRRESVAEKSPLPSKEASRPASVAESIK-DEAEKSKEESRRES 2048
Query: 156 AAVKIKEDKKVNEGEELKEEKKADEGEKLKEDKKDDAGVEI--IEDKKVNEGEELEEEKK 213
A K K E DE EK KE+ + ++ E + K+ + + E K
Sbjct: 2049 VAEKSPLPSKEASRPASVAESIKDEAEKSKEESRRESVAEKSPLPSKEASRPASVAESIK 2108
Query: 214 AEGEELKEDKKVDAGDE---IEEDKKDDNGFEDDKLSEETELSKEE--RESVEAKKP--E 266
E E+ KE+ + ++ E + + + + +E E SKEE RESV K P
Sbjct: 2109 DEAEKSKEESRRESVAEKSPLPSKEASRPASVAESIKDEAEKSKEESRRESVAEKSPLPS 2168
Query: 267 LDAMDEESILEGKDEGSEKEKSQKDRED--DKDKVDNKSNEENIKVEKRLKKRGKGKVNG 324
+A S+ E + +EK K + RE +K + +K V + +K
Sbjct: 2169 KEASRPASVAESIKDEAEKSKEESRRESVAEKSPLPSKEASRPASVAESIKDEA------ 2222
Query: 325 ENVKKKMKELKKIEDIPEAKDESIEKERSRDEEVGDKEKVGGENVKKKMKELKEAEPT-- 382
+K KE + E + E K KE SR V + K E K++ + AE +
Sbjct: 2223 ----EKSKEETRRESVAE-KSPLPSKEASRPASVAESIKDEAEKSKEESRRESAAEKSPL 2277
Query: 383 -TPTTNRPVRERKSVERLVESYDRDASKEFQIEEGRGTPLKNIPNVAFKLSR 433
+ +RP +SV+ + ++ +E E G+ +K + ++SR
Sbjct: 2278 PSKEASRPASVAESVKDEADKSKEESRRESMAESGKAQSIKGDQSPLKEVSR 2329
Score = 74.7 bits (182), Expect = 9e-13
Identities = 128/689 (18%), Positives = 265/689 (37%), Gaps = 101/689 (14%)
Query: 25 DNAVQDLKEDGIKAMEVDKKADGEEVLEMDKLADDGDVVT-----------ENAIKAGDG 73
++ ++ +K++ IK+ E ++ E + D D+ +T EN + A
Sbjct: 1660 ESVLESVKDEPIKSTEKSRRESVAESFKADSTKDEKSPLTSKDISRPESAVENVMDAVGS 1719
Query: 74 EGIKEDEKVNEGKEIKEDKQADEGEELKEDKKDN------------------GGEERKED 115
+ E V +++ + E E+ DK ++ +E+
Sbjct: 1720 AERSQPESVTASRDVSRPESVAESEKDDTDKPESVVESVIPASDVVEIEKGAADKEKGVF 1779
Query: 116 KKVDVGQEVKEDKKVNEGGDIKEEKKADE-------------GEKLKEDKKDDAAVK-IK 161
+++G+ + ++ G + E K + E KE + ++ V+ +K
Sbjct: 1780 VSLEIGKPDSPSEVISRPGPVVESVKPESRRESSTEIVLPCHAEDSKEPSRPESKVECLK 1839
Query: 162 EDKKVNEGEELKEEKKADE--GEKLKEDKKDDAGVEIIEDKKVNEGEELEEEKKAEGEEL 219
++ +V +G +E + + KE + ++ V ++D+ +++ E K +
Sbjct: 1840 DESEVLKGSTRRESVAESDKSSQPFKETSRPESAVGSMKDESMSKEPSRRESVKDGAAQS 1899
Query: 220 KEDKKVDAGDEIEEDKKDDNGFEDDKLSEETELSKEERESVEAKKP--ELDAMDEESILE 277
+E + + E +D DD ++ E T SKE + K P +A S+ E
Sbjct: 1900 RETSRPASVAESAKDGADD--LKELSRPESTTQSKEAGSIKDEKSPLASEEASRPASVAE 1957
Query: 278 GKDEGSEKEKSQKDRED--DKDKVDNKSNEENIKVEKRLKKRGKGKVNGENVKKKMKELK 335
+ +EK K + RE +K + +K V + +K + K KE
Sbjct: 1958 SVKDEAEKSKEESRRESVAEKSPLPSKEASRPASVAESIKDEAE----------KSKEES 2007
Query: 336 KIEDIPEAKDESIEKERSRDEEVGDKEKVGGENVKKKMKELKEAEPTTPTTNRPVRERKS 395
+ E + E K KE SR V + K E K KE E + P +E
Sbjct: 2008 RRESVAE-KSPLPSKEASRPASVAESIKDEAE----KSKEESRRESVAEKSPLPSKEASR 2062
Query: 396 VERLVESYDRDASKEFQIEEGRGTPLKNIPNVAFKLSR-RKVDDTLKFLHTILFCRRGKA 454
+ ES +A K + E R + + P + + SR V +++K + K
Sbjct: 2063 PASVAESIKDEAEKSKE-ESRRESVAEKSPLPSKEASRPASVAESIKDE-----AEKSKE 2116
Query: 455 AVIKKNILRFSGFVWHENEEKQMI--KVKEKFDKCNKEKLLEFSDLLDVPVGNANTRKED 512
++++ S E + +K++ +K +E +R+E
Sbjct: 2117 ESRRESVAEKSPLPSKEASRPASVAESIKDEAEKSKEE-----------------SRRES 2159
Query: 513 IIAKLIDFLVAPQVTKSVLLAE--QEKSAKEKRIAKQGSTGSGTPTSRRSAKSRKKIEDS 570
+ K L + + ++ +AE ++++ K K +++ S +P + A + +S
Sbjct: 2160 VAEK--SPLPSKEASRPASVAESIKDEAEKSKEESRRESVAEKSPLPSKEASRPASVAES 2217
Query: 571 --SIAEKKKTATDTESESEKDEENKEE--NEIDVSDKSEDEKPIKGKKHIAKQGSSRSGT 626
AEK K T ES +EK +E V++ +DE K K+ ++ ++
Sbjct: 2218 IKDEAEKSKEETRRESVAEKSPLPSKEASRPASVAESIKDEAE-KSKEESRRESAAEKSP 2276
Query: 627 ASSRRSAKE*NIFQKERIRCTKQSKESNR 655
S+ +++ ++ + + K +ES R
Sbjct: 2277 LPSKEASRPASVAESVKDEADKSKEESRR 2305
Score = 72.4 bits (176), Expect = 4e-12
Identities = 141/663 (21%), Positives = 261/663 (39%), Gaps = 78/663 (11%)
Query: 26 NAVQDLKEDGIKAMEVDKKADGEEVLEMDKLADDGDVVTENAIKAGDGEGIKEDEKVNEG 85
+ V+ K D K D E VLE K DD + E++ I D
Sbjct: 2835 SVVESTKADSTKG---DISPSPESVLEGPK--DDVEKSKESSRPPSVSASITGDST---- 2885
Query: 86 KEIKEDKQADEGEELKEDKKDNGGEERKEDKKVDVGQEVKEDKKVNEGGDIKEEK----- 140
K++ E + + DK ++ E + + V + + K D K + K+EK
Sbjct: 2886 KDVSRPASVVESVKDEHDKAESRRESIAKVESV-IDEAGKSDSKSSSQDSQKDEKSTLAS 2944
Query: 141 -KADEGEKLKEDKKDDAAV-KIKEDKKVNEGEELKEEKKADEGEKLKEDKKDDAGVEIIE 198
+A E + E KDDA + + + + GE + E K+ D KD + +
Sbjct: 2945 KEASRRESVVESSKDDAEKSESRPESVIASGEPVPRESKSPL------DSKDTSRPGSMV 2998
Query: 199 DKKVNEGEELEEEKKAEGEELKEDKKVDAGDEIEEDKKDDNGFEDDKLSEETELSKEERE 258
+ E E+ E++ + E + E K D + + + D+ L ++ E + R+
Sbjct: 2999 ESVTAEDEKSEQQSRRES--VAESVKADTKKDGKSQEASRPSSVDELLKDDDEKQESRRQ 3056
Query: 259 SVEAKKPELDAMDEESILEGKDEGSE-----------KEKSQKDREDD----KDKVDNKS 303
S+ + M +ES ++ D+ E K ++ KD E +D V
Sbjct: 3057 SITGSHKAMSTMGDESPMDKADKSKEPSRPESVAESIKHENTKDEESPLGSRRDSVAESI 3116
Query: 304 NEENIKVEKRLKKRGKGKVNGENVKKKMKELKKIEDIPEAKDESIEKERSRDEEVG--DK 361
+ K EK K E+V +K+ +K E E+ ES++ E S+D K
Sbjct: 3117 KSDITKGEKS-PLPSKEVSRPESVVGSIKD-EKAESRRESVAESVKPESSKDATSAPPSK 3174
Query: 362 EKVGGENVKKKMKELKEAEPTTPTTNRPVRERKSVERLVESYDRDASKEFQIEEGRGTPL 421
E E+V +K+ + TT+R V S++ + S+E E L
Sbjct: 3175 EHSRPESVLGSLKDEGD-----KTTSRRVSVADSIK---DEKSLLVSQEASRPESEAESL 3226
Query: 422 KNIPNVAFKLSR-RKVDDTLKFLHTILFCRRGKAAVIKKNILRFSGFVWH------ENEE 474
K+ + + SR V +++K GK+ V K R + + E++E
Sbjct: 3227 KDAAAPSQETSRPESVTESVK---------DGKSPVASKEASRPASVAENAKDSADESKE 3277
Query: 475 KQMIKVKEKFDKCNKEKLLEFSDLLDVPVGNANTRKEDIIAKLIDFLVAPQVTKSVLLAE 534
++ + + K++ + + +R+E + + LV+ +V++ +AE
Sbjct: 3278 QRPESLPQSKAGSIKDEKSPLASKDEAEKSKEESRRESVAEQFP--LVSKEVSRPASVAE 3335
Query: 535 QEKSAKEKRIAKQGSTGSGTPTSRRSAKSRKKIEDSSIAEKKKTATDTESESEKDEENKE 594
K EK +K+ S S R A ++D AEK K + ES +EK +
Sbjct: 3336 SVKDEAEK--SKEESPLMSKEAS-RPASVAGSVKDE--AEKSKEESRRESVAEKSPLPSK 3390
Query: 595 E--NEIDVSDKSEDEKPIKGKKHIAKQGSSRSGTASSRRSAKE*NIFQKERIRCTKQSKE 652
E V++ +DE K K+ ++ + +S+ +++ ++ + + K +E
Sbjct: 3391 EASRPASVAESVKDEAD-KSKEESRRESGAEKSPLASKEASRPASVAESIKDEAEKSKEE 3449
Query: 653 SNR 655
S R
Sbjct: 3450 SRR 3452
Score = 68.6 bits (166), Expect = 6e-11
Identities = 93/430 (21%), Positives = 167/430 (38%), Gaps = 63/430 (14%)
Query: 26 NAVQDLKEDGIKAMEVDKKADGEEVLEMDKLADDGDVVTENAIKAGDGEGIKED---EKV 82
+ + +K++ K+ E ++ E + ++K + E KE+ E V
Sbjct: 3693 SVAESVKDEAEKSKEESRRESVAEKSPLPSKEASRPTSVAESVK-DEAEKSKEESRRESV 3751
Query: 83 NEGKEIKEDKQADEGEELKEDKKDNGGEERKEDKKVDVGQEVK-EDKKVNEGGDIKEEKK 141
E K K+A + E KD + ++E ++ V ++ K+ + + E K
Sbjct: 3752 AE-KSSLASKKASRPASVAESVKDEAEKSKEESRRESVAEKSPLASKEASRPASVAESVK 3810
Query: 142 ADEGEKLKED-KKDDAAVKIKEDKKVNEGEELKEEKKADEGEKLKEDKKDDAGVEIIEDK 200
DE EK KE+ +++ A K K E DE +K KE+ + ++G E
Sbjct: 3811 -DEAEKSKEESRRESVAEKSPLPSKEASRPTSVAESVKDEADKSKEESRRESGAE----- 3864
Query: 201 KVNEGEELEEEKKAEGEELKEDKKVDAGDEIEEDKKDDNGFEDDKLSEETELSKEE--RE 258
K+ ++ + + ++ +ETE SKEE RE
Sbjct: 3865 ------------KSPLASMEASRPTSVAESVK---------------DETEKSKEESRRE 3897
Query: 259 SVEAKK--PELDAMDEESILEGKDEGSEKEKSQKDRED--DKDKVDNKSNEENIKVEKRL 314
SV K P +A S+ E + +EK K + RE +K + +K + V + +
Sbjct: 3898 SVTEKSPLPSKEASRPTSVAESVKDEAEKSKEESRRESVAEKSPLASKESSRPASVAESI 3957
Query: 315 KKRGKGKVNGENVKKKMKELKKIEDIPEAKDESIEKERSRDEEV-----GDKEKVGGENV 369
K +G E+ ++ M E K E I + KE SR + V + EK G +
Sbjct: 3958 KDEAEG-TKQESRRESMPESGKAESIKGDQSSLASKETSRPDSVVESVKDETEKPEGSAI 4016
Query: 370 KK-------KMKELKEAEPTTPTTNRPVRERKSVERLVESYDRDASKEFQIEEGRGTPLK 422
K + + + +P +RP +SV ++AS+ + E +P++
Sbjct: 4017 DKSQVASRPESVAVSAKDEKSPLHSRP----ESVADKSPDASKEASRSLSVAETASSPIE 4072
Query: 423 NIPNVAFKLS 432
P LS
Sbjct: 4073 EGPRSIADLS 4082
Score = 67.8 bits (164), Expect = 1e-10
Identities = 136/655 (20%), Positives = 245/655 (36%), Gaps = 107/655 (16%)
Query: 17 PKGGKIFEDNAVQDLKEDGIKAMEVDKKADGEEVLEMDKLADDGDVVTENAIKAGDGEGI 76
P+ +I D +DL + E K+A+ V + L + + + + + +
Sbjct: 1116 PEDERIPLDQIKEDLVIEEKYVKEETKEAEAIVVATVQTLPEAAPLAIDTILASATKDAP 1175
Query: 77 KEDEKVNEGKEIKEDKQADEGEELKEDKKDNGGEERKEDKKVDVGQEVKEDKKVNEGGDI 136
K+ G+ D GE + K ++ + EV D V+E D+
Sbjct: 1176 KDANAEALGE------LPDSGERVLPMKMTFEAQQNLLRDVIKTPDEVA-DLPVHEEADL 1228
Query: 137 K--EEKKADEGEKLKEDKKDDAAVKIKEDKKVNEGEELK--EEKKADEGEK-------LK 185
E+ D G K K++ A KE+K+ ++ +E K E + DE K LK
Sbjct: 1229 GLYEKDSQDAGAKSISHKEESA----KEEKETDDEKENKVGEIELGDEPNKVDISHVLLK 1284
Query: 186 EDKKDDAG-VEIIEDKKVNEGEELEEEKKAEGEELKEDKKVDAGDEIEEDKKDDNGFEDD 244
E ++ A V +IE + EE+ E +E +ED D+ E ++K ++G +
Sbjct: 1285 ESVQEVAEKVVVIETTVEKKQEEIVEATTVITQENQEDLMEQVKDKEEHEQKIESGIITE 1344
Query: 245 KLSEETELSKEERESVEAKKPELDAMDEESILEGKDEGSEKEKSQKDREDDKDKVDNKSN 304
K ++++ + EE+E+ + D+E + D + KS KDRED +
Sbjct: 1345 KEAKKSASTPEEKETSDI------TSDDELPAQLADPTTVPPKSAKDREDTGSIESPPTI 1398
Query: 305 EENIKVEKRLKKRGKGKVNGENVKKKMKELKKIEDIPEAKDESIEKERSRDEEVGDKEKV 364
EE I+VE + K+ + V E I K KE SR E K
Sbjct: 1399 EEAIEVEVQAKQEAQKPVPAPE-----------EAIKTEKSPLASKETSRPESATGSVKE 1447
Query: 365 GGENVKKKMKELKEAEPTTPTTNRPVRERKSVERLVESYDRDASKEFQIEEGRGTPLKNI 424
E K K +P +RP E K K
Sbjct: 1448 DTEQTKSK---------KSPVPSRPESEAKD--------------------------KKS 1472
Query: 425 PNVAFKLSR-RKVDDTLKFLHTILFCRRGKAAVIKKNILRFSGFVWHENEEKQMIKVKEK 483
P + + SR V +++K GKA +++I + +E + K KE+
Sbjct: 1473 PFASGEASRPESVAESVK-------DEAGKAESRRESIAK------THKDESSLDKAKEQ 1519
Query: 484 FDKCNKEKLLEFSDLLDVPVGNANTRKEDIIAKLIDFLVAPQVTKSVLLAEQEKSAKEKR 543
+ +E L E + + E I + L + + ++ + ++ K +
Sbjct: 1520 --ESRRESLAE------------SIKPESGIDEK-SALASKEASRPESVTDKSKEPSRRE 1564
Query: 544 IAKQGSTGSGTPTSRRSAKSRKKIEDSSIAEKKKTATDTESESEKDEENKEENE--IDVS 601
+ T + + S++ S+ E K T+ E + E E + I+
Sbjct: 1565 SIAESLKAESTKDEKSAPPSKEASRPGSVVESVKDETEKSKEPSRRESIAESAKPPIEFR 1624
Query: 602 DKSEDEKPIKG-KKHIAKQGSSRSGTASSRRSAKE*NIFQKERIRCTKQSKESNR 655
+ S E I G K AK S R +S+ +++ ++ + + K +++S R
Sbjct: 1625 EVSRPESVIDGIKDESAKPESRRDSPLASKEASRPESVLESVKDEPIKSTEKSRR 1679
Score = 61.2 bits (147), Expect = 1e-08
Identities = 142/704 (20%), Positives = 274/704 (38%), Gaps = 142/704 (20%)
Query: 25 DNAVQDLKEDGIKAMEVDKKADGEEVLEMDKLADDGDVVTENAIKAGDGEGIKEDEKVNE 84
+ V+ +E+ ++A V + + E+++E K ++ + E+ I KE +K
Sbjct: 1298 ETTVEKKQEEIVEATTVITQENQEDLMEQVKDKEEHEQKIESGIITE-----KEAKKSAS 1352
Query: 85 GKEIKEDKQADEGEELK--------------EDKKDNGGEERKEDKKVDVGQEVKEDKKV 130
E KE +EL +D++D G E + + EV+ ++
Sbjct: 1353 TPEEKETSDITSDDELPAQLADPTTVPPKSAKDREDTGSIESPPTIEEAIEVEVQAKQEA 1412
Query: 131 NEGGDIKEEKKADEGEKL--KEDKKDDAAV-KIKEDKKVNEGE----------ELKEEK- 176
+ EE E L KE + ++A +KED + + + E K++K
Sbjct: 1413 QKPVPAPEEAIKTEKSPLASKETSRPESATGSVKEDTEQTKSKKSPVPSRPESEAKDKKS 1472
Query: 177 -----KADEGEKLKEDKKDDAGV-----EII-----EDKKVNEGEELEEEKKAEGEELKE 221
+A E + E KD+AG E I ++ +++ +E E +++ E +K
Sbjct: 1473 PFASGEASRPESVAESVKDEAGKAESRRESIAKTHKDESSLDKAKEQESRRESLAESIKP 1532
Query: 222 DKKVDAG-----------DEIEEDKKDDNGFEDDKLSEETELSKEERESVEAKKPELDAM 270
+ +D + + + K+ + E S + E +K+E+ + P +A
Sbjct: 1533 ESGIDEKSALASKEASRPESVTDKSKEPSRRESIAESLKAESTKDEKSA----PPSKEAS 1588
Query: 271 DEESILEGKDEGSEKEKSQKDREDDKDKVDNKSNEENIK--VEKRLKKRGKGKVNGENVK 328
S++E + +EK K RE S E+ K +E R R + ++G
Sbjct: 1589 RPGSVVESVKDETEKSKEPSRRE---------SIAESAKPPIEFREVSRPESVIDG---- 1635
Query: 329 KKMKELKKIEDIPEAKDESIEKERSRDEEVGDKEKVGGENVKKKMKELKEAEPTTPTTNR 388
KDES + E RD + KE E+V + +K+ EP T
Sbjct: 1636 --------------IKDESAKPESRRDSPLASKEASRPESVLESVKD----EPIKST--- 1674
Query: 389 PVRERKSVERLVESYDRDASKEFQIEEGRGTPLKNIPNVAFKLSRRKVDDTLKFLHTILF 448
E+ E + ES+ D++K+ +PL + K R + +
Sbjct: 1675 ---EKSRRESVAESFKADSTKD------EKSPLTS------KDISRPESAVENVMDAVGS 1719
Query: 449 CRRGKAAVIKKNILRFSGFVWHENEEKQMIKVKEKFDKCNKEKLLE----FSDLLDVPVG 504
R + + + + + + EK D E ++E SD++++ G
Sbjct: 1720 AERSQPESVTAS---------RDVSRPESVAESEKDDTDKPESVVESVIPASDVVEIEKG 1770
Query: 505 NANTRKEDIIAKLIDFLVAPQ--VTKSVLLAEQEKSAKEKRIAKQGSTGSGTPTSRRSAK 562
A+ K ++ I +P +++ + E K + + + S+ ++
Sbjct: 1771 AADKEKGVFVSLEIGKPDSPSEVISRPGPVVESVKPESRRESSTEIVLPCHAEDSKEPSR 1830
Query: 563 SRKKIE---DSSIAEKKKTATDTESESEKD-----EENKEENEI-DVSDKSEDEKPIKGK 613
K+E D S K T ++ +ES+K E ++ E+ + + D+S ++P + +
Sbjct: 1831 PESKVECLKDESEVLKGSTRRESVAESDKSSQPFKETSRPESAVGSMKDESMSKEPSRRE 1890
Query: 614 --KHIAKQGSSRSGTASSRRSAKE--*NIFQKERIRCTKQSKES 653
K A Q S AS SAK+ ++ + R T QSKE+
Sbjct: 1891 SVKDGAAQSRETSRPASVAESAKDGADDLKELSRPESTTQSKEA 1934
Score = 60.5 bits (145), Expect = 2e-08
Identities = 121/599 (20%), Positives = 243/599 (40%), Gaps = 89/599 (14%)
Query: 85 GKEIKEDKQADEGEELKEDKKDNGGEERKEDKKVDVGQEVKEDKKVNEGGDIKEEKKAD- 143
G +K+ K + +LK+ + D GG E KK+ D+ ++ D
Sbjct: 826 GSPVKQAKP--KAADLKKTRLDKGGTTDSSLVSTPSADEATAAKKLQ---DLTASQELDA 880
Query: 144 EGEKLKEDKKDDAAVKIKEDKKVNEGEELKEEKKADEGEKLKEDKKDDAGVEIIEDKKVN 203
E ++ +D K++ V ++E + V +E+K ++ +L+E + G + + +
Sbjct: 881 EKQRELDDLKEEQEV-VREIEAVFSRDEMKRQQHQQIKAELREMPAEGTGDG---ENEPD 936
Query: 204 EGEELEEEKKAEGEELKEDKKVDAGDEIEEDKKDDNGFEDDKLSEETELSKEERESVEAK 263
E EE +K E E+ ED V+ + ++++ D + SE+ K E +EA
Sbjct: 937 EEEEYLIIEKEEVEQYTEDSIVEQESSMTKEEEIQKHQRDSQESEKKR-KKSAEEEIEAA 995
Query: 264 KPELDAMDEESILEGKDEGSEKEKSQKDREDDKDKVDNKSNEENI----------KVEKR 313
+++A + ++ LEG + +++S+ D E ++ K+ K+ ++I + E++
Sbjct: 996 IAKVEAAERKARLEGAS--ARQDESELDVEPEQSKI--KAEVQDIIATAKDIAKSRTEEQ 1051
Query: 314 LKKRGKGKVNG----ENVKKKMKELKKI--------------EDIPEAK-DESIEKERSR 354
L K + +++ E + KK + K E +PE K +IE +
Sbjct: 1052 LAKPAEEELSSPTPEEKLSKKTSDTKDDQIGAPVDVLPVNLQESLPEEKFSATIESGATT 1111
Query: 355 DEEVGDKEKVGGENVKKKM--------KELKEAEPTTPTTNRPVRERK--SVERLVESYD 404
+ + E++ + +K+ + +E KEAE T + + E +++ ++ S
Sbjct: 1112 APTLPEDERIPLDQIKEDLVIEEKYVKEETKEAEAIVVATVQTLPEAAPLAIDTILASAT 1171
Query: 405 RDASKEFQIEE--------GRGTPLKNIPNVAFKLSRRKVDDTLKFLHTILFCRRGKAAV 456
+DA K+ E R P+K + F+ + + D +K + + A
Sbjct: 1172 KDAPKDANAEALGELPDSGERVLPMK----MTFEAQQNLLRDVIKTPDEVADLPVHEEAD 1227
Query: 457 IKKNILRFSGFVWHENEEKQMIKVKEKFDKCNKEKLLEFSDLLDVPVGNANT----RKED 512
+ G ++++ + K + +EK E D + VG K D
Sbjct: 1228 L--------GLYEKDSQDAGAKSISHKEESAKEEK--ETDDEKENKVGEIELGDEPNKVD 1277
Query: 513 IIAKLIDFLVAPQVTKSVLLA-----EQEKSAKEKRIAKQGSTGSGTPTSRRSAKSRKKI 567
I L+ V K V++ +QE+ + + Q + + + +KI
Sbjct: 1278 ISHVLLKESVQEVAEKVVVIETTVEKKQEEIVEATTVITQENQEDLMEQVKDKEEHEQKI 1337
Query: 568 EDSSIAEK--KKTATDTESESEKDEENKEENEIDVSDKSEDEKPIKGKKHIAKQGSSRS 624
E I EK KK+A+ E + D + +E ++D + P K K GS S
Sbjct: 1338 ESGIITEKEAKKSASTPEEKETSDITSDDELPAQLADPT--TVPPKSAKDREDTGSIES 1394
Score = 58.9 bits (141), Expect = 5e-08
Identities = 91/421 (21%), Positives = 170/421 (39%), Gaps = 55/421 (13%)
Query: 26 NAVQDLKEDGIKAMEVDKKADGEEVLEMDKLADDGDVVTENAIKAGDGEGIKEDEKVNEG 85
+ + +K++ K+ E ++ E V E L E + A E IK++ + ++
Sbjct: 2065 SVAESIKDEAEKSKEESRR---ESVAEKSPLPSK-----EASRPASVAESIKDEAEKSKE 2116
Query: 86 KEIKED---------KQADEGEELKEDKKDNGGEERKEDKKVDVGQEVK-EDKKVNEGGD 135
+ +E K+A + E KD + ++E ++ V ++ K+ +
Sbjct: 2117 ESRRESVAEKSPLPSKEASRPASVAESIKDEAEKSKEESRRESVAEKSPLPSKEASRPAS 2176
Query: 136 IKEEKKADEGEKLKEDKKDDAAVK--------------IKEDKKVNEGEELKEEKKADE- 180
+ E K DE EK KE+ + ++ + + E K +E E+ KEE + +
Sbjct: 2177 VAESIK-DEAEKSKEESRRESVAEKSPLPSKEASRPASVAESIK-DEAEKSKEETRRESV 2234
Query: 181 GEKL----KEDKKDDAGVEIIEDKKVNEGEELEEEKKAEGEELKEDKKVDAGDEIEEDKK 236
EK KE + + E I+D+ EE E AE L K+ + E K
Sbjct: 2235 AEKSPLPSKEASRPASVAESIKDEAEKSKEESRRESAAEKSPL-PSKEASRPASVAESVK 2293
Query: 237 DDNGFEDDKLSEETELSKEERESVEA-KKPELDAMDEESILEGKDEGSEKEKSQKDREDD 295
D+ ++ E+ + +S++ + P + ES+ E + K K RE
Sbjct: 2294 DEADKSKEESRRESMAESGKAQSIKGDQSPLKEVSRPESVAESVKDDPVKSKEPSRRESV 2353
Query: 296 KDKVDNKSNEENIKVEKRLKKRGKGKVNGENVKKKMK-ELKKIEDIPEAKDESIEKERSR 354
V S ++ + KG E+V +K E +K E E+K ES+ +++
Sbjct: 2354 AGSVTADSARDD-----QSPLESKGASRPESVVDSVKDEAEKQESRRESKTESVIPPKAK 2408
Query: 355 DEEVGDKEKVGGENVKKKMKELKEAEPTTPTTNRPVRERKSVERLVESYDRD-----ASK 409
D++ KE + ++ + ++E +A+ + R E + S RD ASK
Sbjct: 2409 DDK-SPKEVLQPVSMTETIRE--DADQPMKPSQAESRRESIAESIKASSPRDEKSPLASK 2465
Query: 410 E 410
E
Sbjct: 2466 E 2466
Score = 53.1 bits (126), Expect = 3e-06
Identities = 123/625 (19%), Positives = 227/625 (35%), Gaps = 116/625 (18%)
Query: 110 EERKE---DKKVDVGQEVKEDKKVNEGGDIKEEKKADEG--------EKLKEDKKDDAAV 158
EER E + D + V++ K + + E KAD E + E KDD
Sbjct: 2807 EERPESPAESAKDAAESVEKSKDASRPPSVVESTKADSTKGDISPSPESVLEGPKDDV-- 2864
Query: 159 KIKEDKKVNEGEELKEEKKADEGEKLKEDKKDDAGVEIIEDKKVNEGEELEEEKKAEGEE 218
+K E + G+ K+ + + VE ++D E KAE
Sbjct: 2865 -----EKSKESSRPPSVSASITGDSTKDVSRPASVVESVKD----------EHDKAESRR 2909
Query: 219 LKEDKKVDAGDEIEEDKKDDNGFEDDKLSEETELSKEERESVEAKKPELDAMDEESILEG 278
K E D+ G D K S + + K+E+ ++ +K +A ES++E
Sbjct: 2910 ESIAKV--------ESVIDEAGKSDSKSSSQ-DSQKDEKSTLASK----EASRRESVVES 2956
Query: 279 KDEGSEKEKSQKDR---------EDDKDKVDNKSNE-----------ENIKVEKRLKKRG 318
+ +EK +S+ + + K +D+K E+ K E++ ++
Sbjct: 2957 SKDDAEKSESRPESVIASGEPVPRESKSPLDSKDTSRPGSMVESVTAEDEKSEQQSRRES 3016
Query: 319 KGKVNGENVKK--KMKELKKIEDIPEAKDESIEKERSRDEEVGDKEK----VGGENVKKK 372
+ + KK K +E + + E + EK+ SR + + K +G E+ K
Sbjct: 3017 VAESVKADTKKDGKSQEASRPSSVDELLKDDDEKQESRRQSITGSHKAMSTMGDESPMDK 3076
Query: 373 MKELKEAEPTTPTTNRPVRERKSVERLVESYDRDA---SKEFQIEEGRGTPL--KNIPNV 427
+ KE E E RD+ S + I +G +PL K +
Sbjct: 3077 ADKSKEPSRPESVAESIKHENTKDEESPLGSRRDSVAESIKSDITKGEKSPLPSKEVSRP 3136
Query: 428 AFKLSRRKVDDTLKFLHTILFCRRGKAAVIKKNILRFSGFVWHENEEKQMIKVKEKFDKC 487
+ K + ++ + +++ K+ H E + +K++ DK
Sbjct: 3137 ESVVGSIKDEKAESRRESVAESVKPESS---KDATSAPPSKEHSRPESVLGSLKDEGDKT 3193
Query: 488 NKEKLLEFSDLLD---VPVGNANTRKEDIIAKLIDFLVAPQVT-KSVLLAEQEKSAKEKR 543
++ + D + V +R E L D Q T + + E K K
Sbjct: 3194 TSRRVSVADSIKDEKSLLVSQEASRPESEAESLKDAAAPSQETSRPESVTESVKDGKSPV 3253
Query: 544 IAKQGS-TGSGTPTSRRSAKSRKKIEDSSIA---------EKKKTATDTESESEKDEENK 593
+K+ S S ++ SA K+ S+ EK A+ E+E K+E +
Sbjct: 3254 ASKEASRPASVAENAKDSADESKEQRPESLPQSKAGSIKDEKSPLASKDEAEKSKEESRR 3313
Query: 594 E--------------------ENEIDVSDKSEDEKPIKGK---KHIAKQGSSRSGTASSR 630
E E+ D ++KS++E P+ K + + GS + S+
Sbjct: 3314 ESVAEQFPLVSKEVSRPASVAESVKDEAEKSKEESPLMSKEASRPASVAGSVKDEAEKSK 3373
Query: 631 RSAKE*NIFQKERIRCTKQSKESNR 655
++ ++ +K + SKE++R
Sbjct: 3374 EESRRESVAEKSPL----PSKEASR 3394
Score = 48.1 bits (113), Expect = 9e-05
Identities = 124/623 (19%), Positives = 215/623 (33%), Gaps = 115/623 (18%)
Query: 26 NAVQDLKEDGIKAMEVDKKADGEEVLEMDKLADDGDVVTENAIKAGDGEGIKED---EKV 82
+ + +K++ K+ E ++ G E + + ++K + E KE+ E V
Sbjct: 3841 SVAESVKDEADKSKEESRRESGAEKSPLASMEASRPTSVAESVK-DETEKSKEESRRESV 3899
Query: 83 NEGKEIKEDKQADEGEELKEDKKDNGGEERKEDKKVDVGQEVKEDKKVNEGGDIKEEKKA 142
E K K+A + E KD + ++E ++ V ++ K + E
Sbjct: 3900 TE-KSPLPSKEASRPTSVAESVKDEAEKSKEESRRESVAEKSPLASKESSRPASVAESIK 3958
Query: 143 DEGEKLKEDKKDDAAVKIKEDKKVNEGEELKEEKKADEGE-KLKEDKKDDAGVEIIEDKK 201
DE E K++ + ++ + E K E K D+ KE + D+ VE ++D
Sbjct: 3959 DEAEGTKQESRRES---MPESGKA-------ESIKGDQSSLASKETSRPDSVVESVKD-- 4006
Query: 202 VNEGEELEEEKKAEGEELKEDKKVDAGDEIEEDKKDDNGFEDDKLSEETELSKEERESVE 261
E +K EG + + + + + KD E++ L ESV
Sbjct: 4007 --------ETEKPEGSAIDKSQVASRPESVAVSAKD----------EKSPLHSRP-ESVA 4047
Query: 262 AKKPELDAMDEESILEGKDEGSEKEKSQKDREDDKDKVDNKSNEENIKVEKRLKKRGKGK 321
K P+ S+ + S E+ + D + + L KG
Sbjct: 4048 DKSPDASKEASRSLSVAETASSPIEEGPRSIAD-------------LSLPLNLTGEAKG- 4093
Query: 322 VNGENVKKKMKELKKIEDIPEAKDESIEKERSRDEEVGDKEKVGGENVKKKMKELKEAEP 381
K+ L D+ E GD +V E+ + K AE
Sbjct: 4094 --------KLPTLSSPIDVAE----------------GDFLEVKAESSPRPAVLSKPAEF 4129
Query: 382 TTP----TTNRPVRERKSVERLVESYDRDASKEFQIEEGRGTPLKNIPNVAFKLSRRKVD 437
+ P T + PV E V +E ++ + G G L+ K +
Sbjct: 4130 SQPDTGHTASTPVDEASPVLEEIEVVEQHTT------SGVGATGATAETDLLDLTETKSE 4183
Query: 438 DTLKFLHTILFCRRGKAAVIKKNILRFSGFVWHENEEKQMIKVK----------EKFDKC 487
K T LF K +L S + EEK VK E+ K
Sbjct: 4184 TVTKQSETTLFETLTSKVESKVEVLESS---VKQVEEKVQTSVKQAETTVTDSLEQLTKK 4240
Query: 488 NKEKLLEFSDLLDVPVGNANTRKEDIIAKLIDFLVAPQVTKSVLLAEQEKSAKEKRIAKQ 547
+ E+L E +LD I+A + L + + ++ E+ +E K
Sbjct: 4241 SSEQLTEIKSVLDTNFEEV----AKIVADVAKVLKSDKDITDIIPDFDERQLEE----KL 4292
Query: 548 GSTGSGTPTSRRSAKSRKKIEDSSIAEKKKTATDTESESEKDEENKEENEIDVSDKSEDE 607
ST S +S + K +E S E ESEK +++ I + +K + E
Sbjct: 4293 KSTADTEEESDKSTRDEKSLEIS---------VKVEIESEKSSPDQKSGPISIEEKDKIE 4343
Query: 608 KPIKGKKHIAKQGSSRSGTASSR 630
+ K + SSR + +S+
Sbjct: 4344 QSEKAQLRQGILTSSRPESVASQ 4366
Score = 47.8 bits (112), Expect = 1e-04
Identities = 137/721 (19%), Positives = 276/721 (38%), Gaps = 141/721 (19%)
Query: 36 IKAMEVDKKADGEEVLEMDKLADDGDVVTE-NAIKAGDGEGIKEDEKVNEGKEIKE---- 90
++ + ++ D E+ E+D L ++ +VV E A+ + D ++ +++ E++E
Sbjct: 869 LQDLTASQELDAEKQRELDDLKEEQEVVREIEAVFSRDEMKRQQHQQIKA--ELREMPAE 926
Query: 91 -----DKQADEGEELKEDKKDNGGEERKEDKKVDVGQEVKEDKKVNEGGDIKEEKKADEG 145
+ + DE EE +K+ E+ ED V+ + +++++ K ++ + E
Sbjct: 927 GTGDGENEPDEEEEYLIIEKEE-VEQYTEDSIVEQESSMTKEEEIQ-----KHQRDSQES 980
Query: 146 EKLKEDKKDD------AAVKIKEDKKVNEGEELKEEKKADEGEKLKEDKKDDAGVEIIED 199
EK ++ ++ A V+ E K EG ++++ + E + K + I
Sbjct: 981 EKKRKKSAEEEIEAAIAKVEAAERKARLEGASARQDESELDVEPEQSKIKAEVQDIIATA 1040
Query: 200 KKVNEGEELEEEKKAEGEELKEDKKVDAGDEIEEDKKDD--------------NGFEDDK 245
K + + E+ K EEL + + D KDD ++K
Sbjct: 1041 KDIAKSRTEEQLAKPAEEELSSPTPEEKLSKKTSDTKDDQIGAPVDVLPVNLQESLPEEK 1100
Query: 246 LSEETELSKEERESV-EAKKPELDAMDEESILEG---KDEGSEKE-----KSQKDREDDK 296
S E ++ E ++ LD + E+ ++E K+E E E Q E
Sbjct: 1101 FSATIESGATTAPTLPEDERIPLDQIKEDLVIEEKYVKEETKEAEAIVVATVQTLPEAAP 1160
Query: 297 DKVDN--KSNEENIKVEKRLKKRGKGKVNGENV-KKKM---KELKKIEDIPEAKDESIEK 350
+D S ++ + + G+ +GE V KM + + D+ + DE +
Sbjct: 1161 LAIDTILASATKDAPKDANAEALGELPDSGERVLPMKMTFEAQQNLLRDVIKTPDEVADL 1220
Query: 351 ERSRDEEVG----DKEKVGGENVKKKMKELKEAEPTTPTTNRPVRERKSVERLVESYDRD 406
+ ++G D + G +++ K + KE + E+ D
Sbjct: 1221 PVHEEADLGLYEKDSQDAGAKSISHKEESAKEEK--------------------ETDDEK 1260
Query: 407 ASKEFQIEEGRGTPLKNIPNVAFKLSRRKVDDTLKFLHTILFCRRGKAAVIKKNILRFSG 466
+K +IE G +I +V K S ++V + + + T + + ++ I+ +
Sbjct: 1261 ENKVGEIELGDEPNKVDISHVLLKESVQEVAEKVVVIETTVEKK-------QEEIVEATT 1313
Query: 467 FVWHENEEKQMIKVKEKFDKCNK------------------------------EKLLEFS 496
+ EN+E M +VK+K + K E + +
Sbjct: 1314 VITQENQEDLMEQVKDKEEHEQKIESGIITEKEAKKSASTPEEKETSDITSDDELPAQLA 1373
Query: 497 DLLDVPVGNANTRKEDIIAKLIDFLVAPQVTKSVLLAEQEKS-------AKEKRIAKQGS 549
D VP +A R++ + P + +++ + Q K A E+ I + S
Sbjct: 1374 DPTTVPPKSAKDREDTGSIE-----SPPTIEEAIEVEVQAKQEAQKPVPAPEEAIKTEKS 1428
Query: 550 TGSGTPTSRRSAKSRKKIEDSSIAEKKKTATDTESESE-KDE------------ENKEEN 596
+ TSR + + ED+ + KK+ + ESE KD+ E+ E+
Sbjct: 1429 PLASKETSRPESATGSVKEDTEQTKSKKSPVPSRPESEAKDKKSPFASGEASRPESVAES 1488
Query: 597 EIDVSDKSEDEKPIKGKKHIAKQGSSRSGTASSRRSAKE*NIFQKERI--RCTKQSKESN 654
D + K+E + K H + ++ SRR + +I + I + SKE++
Sbjct: 1489 VKDEAGKAESRRESIAKTHKDESSLDKAKEQESRRESLAESIKPESGIDEKSALASKEAS 1548
Query: 655 R 655
R
Sbjct: 1549 R 1549
Score = 47.4 bits (111), Expect = 2e-04
Identities = 96/474 (20%), Positives = 177/474 (37%), Gaps = 53/474 (11%)
Query: 182 EKLKEDKKDDAGVEIIEDKKVNEGEELEEEKKAEGEELKEDKKVDAGDEIEEDKKDDNGF 241
EK D+A +I E E K E +++ K + E K D+
Sbjct: 2787 EKTASSPIDEAPKSLIGCPAEERPESPAESAKDAAESVEKSKDASRPPSVVESTKADSTK 2846
Query: 242 EDDKLSEETELSKEERESVEAKKPELDAMDEESILEGKDEGSEKEKSQKDR-EDDKDKVD 300
D S E+ L + + ++K+ SI + + S + +D+ DK +
Sbjct: 2847 GDISPSPESVLEGPKDDVEKSKESSRPPSVSASITGDSTKDVSRPASVVESVKDEHDKAE 2906
Query: 301 NKSNEENIKVEKRLKKRGK--GKVNGENVKK------KMKELKKIEDIPEAKDESIEKER 352
++ E KVE + + GK K + ++ +K KE + E + E+ + EK
Sbjct: 2907 SR-RESIAKVESVIDEAGKSDSKSSSQDSQKDEKSTLASKEASRRESVVESSKDDAEKSE 2965
Query: 353 SRDEEVGDKEKVGGENVKKKMKELKEAEPTTPTTNRPVRERKSVERLVESYDRDASKEFQ 412
SR E V GE V ++ K +++ T+RP +SV E ++ + +E
Sbjct: 2966 SRPESV----IASGEPVPRESKSPLDSK----DTSRPGSMVESVTAEDEKSEQQSRRESV 3017
Query: 413 IEEGRGTPLKNIPNVAFKLSR-RKVDDTLKFLHTILFCRRGKAAVIKKNILRFSGFVWHE 471
E + K+ + + SR VD+ LK RR +
Sbjct: 3018 AESVKADTKKD--GKSQEASRPSSVDELLKDDDEKQESRRQS--------------ITGS 3061
Query: 472 NEEKQMIKVKEKFDKCNKEKLLEFSDLLDVPVGNANTRKEDIIAKLIDFLVAPQVTKSVL 531
++ + + DK +K K + + + + NT+ E+ VA + +
Sbjct: 3062 HKAMSTMGDESPMDKADKSKEPSRPESVAESIKHENTKDEESPLGSRRDSVAESIKSDI- 3120
Query: 532 LAEQEKSAKEKRIAKQGSTGSGTPTSRRSAKSRKKIEDSSIAEKKKTATDTESESE---- 587
+ EKS + + + G+ ++ R+ + +S E K AT E
Sbjct: 3121 -TKGEKSPLPSKEVSRPESVVGSIKDEKAESRRESVAESVKPESSKDATSAPPSKEHSRP 3179
Query: 588 -------KDEENK-EENEIDVSDKSEDEKPIKGKKHIAKQGSSRSGTASSRRSA 633
KDE +K + V+D +DEK + ++++ S A S + A
Sbjct: 3180 ESVLGSLKDEGDKTTSRRVSVADSIKDEKSLL----VSQEASRPESEAESLKDA 3229
Score = 43.9 bits (102), Expect = 0.002
Identities = 102/456 (22%), Positives = 173/456 (37%), Gaps = 45/456 (9%)
Query: 195 EIIEDKKVNEGEELEEEKKAEGEELKEDKK---VDAGDEIEE-DKKDDNGFEDDKLSEET 250
E + K ++ E LE K E+++ K D +E+ KK + K +T
Sbjct: 4195 ETLTSKVESKVEVLESSVKQVEEKVQTSVKQAETTVTDSLEQLTKKSSEQLTEIKSVLDT 4254
Query: 251 ELSKEERESVEAKKPELDAMDEESILEGKDEGS--EKEKSQKDREDDKDKV--DNKSNEE 306
+ + + K D I+ DE EK KS D E++ DK D KS E
Sbjct: 4255 NFEEVAKIVADVAKVLKSDKDITDIIPDFDERQLEEKLKSTADTEEESDKSTRDEKSLEI 4314
Query: 307 NIKVEKRLKKRGKGKVNGENVKKKMKELKKIEDIPEAKDESIEKERSRDEEVGDK-EKVG 365
++KVE +K + +G ++E KIE +A+ SR E V + E V
Sbjct: 4315 SVKVEIESEKSSPDQKSGPI---SIEEKDKIEQSEKAQLRQGILTSSRPESVASQPESVP 4371
Query: 366 GENVKKKMKELKEAEPT----TPTTNRPVRERKSVERLVESYDRDASKEFQIEEGRGTPL 421
+ E KE E + ++RP V R AS Q G
Sbjct: 4372 SPSQSAASHEHKEVELSESHKAEKSSRPESVASQVSEKDMKTSRPASSTSQFSTKEGDE- 4430
Query: 422 KNIPNVAFKLSRRKVDDTLKFLHTILFCRRGKAAVIKKNILRFSGFVW--HENEEKQMIK 479
+ ++ L+ + +T + F +V K +L V E+ + +
Sbjct: 4431 ETTESLLHSLTTTETVETKQMEEKSSF-ESVSTSVTKSTVLSSQSTVQLREESTSESLSS 4489
Query: 480 VKEKFDKCNKEKLLEFSDLLDVPVGNANTR--KEDIIAKLIDFLVAPQVTKSVLLAEQEK 537
+ D +E L S LL G A KED A A Q+ + LL + E+
Sbjct: 4490 SLKVEDSSRRESL---SSLLAEKGGIATNTSLKEDTSAS------ASQLEE--LLVQSEE 4538
Query: 538 SAKEKRIAKQGSTGSGTPTSRRSAKSRKKIEDSSIAEKKKTATDTESESEKDEENKEENE 597
+ E +++ ++ + KS K+I+D+ + T T S + KD+ KE
Sbjct: 4539 CSSESIVSEIQTS--------IAQKSNKEIKDARETKVTSQFTTTTSSATKDDSLKE--- 4587
Query: 598 IDVSDKSEDEKPIKGKKHIAKQGSSRSGTASSRRSA 633
V++ EK + K+ + + + + + +A
Sbjct: 4588 -TVAEFLATEKIVSAKEAFSTEATKSADDCLKKTTA 4622
Database: sprot
Posted date: Nov 25, 2004 10:54 AM
Number of letters in database: 59,974,054
Number of sequences in database: 164,201
Lambda K H
0.309 0.131 0.346
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 95,634,623
Number of Sequences: 164201
Number of extensions: 4891029
Number of successful extensions: 82702
Number of sequences better than 10.0: 3090
Number of HSP's better than 10.0 without gapping: 800
Number of HSP's successfully gapped in prelim test: 2369
Number of HSP's that attempted gapping in prelim test: 28519
Number of HSP's gapped (non-prelim): 20842
length of query: 797
length of database: 59,974,054
effective HSP length: 118
effective length of query: 679
effective length of database: 40,598,336
effective search space: 27566270144
effective search space used: 27566270144
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.6 bits)
S2: 70 (31.6 bits)
Medicago: description of AC122165.9