BLAST2 result
BLASTP 2.2.2 [Dec-14-2001]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= AC121245.8 - phase: 0
(665 letters)
Database: sprot
164,201 sequences; 59,974,054 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
ABG2_HUMAN (Q9UNQ0) ATP-binding cassette, sub-family G, member 2... 257 6e-68
ABG8_HUMAN (Q9H221) ATP-binding cassette, sub-family G, member 8... 232 3e-60
YPC3_CAEEL (Q11180) Putative ABC transporter C05D10.3 in chromos... 227 7e-59
ABG1_HUMAN (P45844) ATP-binding cassette, sub-family G, member 1... 222 3e-57
ABG8_RAT (P58428) ATP-binding cassette, sub-family G, member 8 (... 218 4e-56
WHIT_DROME (P10090) White protein 213 2e-54
SCRT_DROME (P45843) Scarlet protein 209 2e-53
ABG8_MOUSE (Q9DBM0) ATP-binding cassette, sub-family G, member 8... 209 2e-53
WHIT_LUCCU (Q05360) White protein 207 5e-53
WHIT_CERCA (Q17320) White protein 207 7e-53
ABG4_HUMAN (Q9H172) ATP-binding cassette, sub-family G, member 4 207 7e-53
ABG5_HUMAN (Q9H222) ATP-binding cassette, sub-family G, member 5... 207 9e-53
YOH5_YEAST (Q08234) Probable ATP-dependent transporter YOL074C/Y... 205 3e-52
WHIT_ANOGA (Q27256) White protein 203 1e-51
ABG5_MOUSE (Q99PE8) ATP-binding cassette, sub-family G, member 5... 199 1e-50
ABG3_MOUSE (Q99P81) ATP-binding cassette, sub-family G, member 3 199 1e-50
ABG5_RAT (Q99PE7) ATP-binding cassette, sub-family G, member 5 (... 195 3e-49
CDR3_CANAL (O42690) Opaque-specific ABC transporter CDR3 186 2e-46
YQ5C_CAEEL (Q09466) Putative ABC transporter C16C10.12 in chromo... 186 2e-46
CDR4_CANAL (O74676) ABC transporter CDR4 185 4e-46
>ABG2_HUMAN (Q9UNQ0) ATP-binding cassette, sub-family G, member 2
(Placenta-specific ATP-binding cassette transporter)
(Breast cancer resistance protein)
Length = 655
Score = 257 bits (657), Expect = 6e-68
Identities = 195/620 (31%), Positives = 316/620 (50%), Gaps = 30/620 (4%)
Query: 24 KGVCLTWKDLWVTVSASTG----KTNESKSILQGLTGYAKPAQLLAIMGPSGCGKSTLLD 79
+G L++ ++ V +G + K IL + G KP L AI+GP+G GKS+LLD
Sbjct: 33 EGAVLSFHNICYRVKLKSGFLPCRKPVEKEILSNINGIMKPG-LNAILGPTGGGKSSLLD 91
Query: 80 ALAGRLGSNTRQSGDILINGNKQALAYG-TSAYVTQDDTLLTTLTVKEAVYYSAQLQLPD 138
LA R + SGD+LING + + S YV QDD ++ TLTV+E + +SA L+L
Sbjct: 92 VLAARKDPSGL-SGDVLINGAPRPANFKCNSGYVVQDDVVMGTLTVRENLQFSAALRLAT 150
Query: 139 TMSNEEKKERADFTIREMGLQDAINTRIGGWGVKGISGGQKRRVSISIEILTRPRLLFLD 198
TM+N EK ER + I E+GL ++++G ++G+SGG+++R SI +E++T P +LFLD
Sbjct: 151 TMTNHEKNERINRVIEELGLDKVADSKVGTQFIRGVSGGERKRTSIGMELITDPSILFLD 210
Query: 199 EPTSGLDSAASYYVMKRIASLDKKDGIQRTIVASIHQPSTEVFQLFHNLCLLSSGKTVYF 258
EPT+GLDS+ + V+ + + K+ RTI+ SIHQP +F+LF +L LL+SG+ ++
Sbjct: 211 EPTTGLDSSTANAVLLLLKRMSKQG---RTIIFSIHQPRYSIFKLFDSLTLLASGRLMFH 267
Query: 259 GPASAASEFFASNGFPCPPLQNPSDHLLKTINKDFDQ---DIEMDLSETGTISIEQ---- 311
GPA A +F S G+ C NP+D L IN D + E D T I +
Sbjct: 268 GPAQEALGYFESAGYHCEAYNNPADFFLDIINGDSTAVALNREEDFKATEIIEPSKQDKP 327
Query: 312 AIDILVSSYSSSERNQEIKNEVSVLSIVLSLKDNNSTYKK--KHAGFLNQCLVLTRRSFV 369
I+ L Y +S +E K E+ LS K + +K+ F +Q +++RSF
Sbjct: 328 LIEKLAEIYVNSSFYKETKAELHQLS-GGEKKKKITVFKEISYTTSFCHQLRWVSKRSFK 386
Query: 370 NMFRDLGYYWLRLGIYIALAISLATVFNDLDKSNGSIQDRGSLLMFVFSFLTFMTIGGFP 429
N+ + ++ + + L + + ++ L + IQ+R +L F+ + F ++
Sbjct: 387 NLLGNPQASIAQIIVTVVLGLVIGAIYFGLKNDSTGIQNRAGVLFFLTTNQCFSSVSAVE 446
Query: 430 SYVEDMKVFERERLNGHYGVTAYVIGNTLS-AIPYLLMISLIPGAIAYYPPGLQKGFEHF 488
+V + K+F E ++G+Y V++Y +G LS +P ++ S+I I Y+ GL+ + F
Sbjct: 447 LFVVEKKLFIHEYISGYYRVSSYFLGKLLSDLLPMRMLPSIIFTCIVYFMLGLKPKADAF 506
Query: 489 IYFICALFSCLMLVESLMMIVASIVPDFLMGIITGAGIQGIMMLAGGFFRLPNDLPNPFW 548
+ L S+ + +A+ + + MM+ G L N W
Sbjct: 507 FVMMFTLMMVAYSASSMALAIAAGQSVVSVATLLMTICFVFMMIFSGL--LVNLTTIASW 564
Query: 549 RYPMFYISFHRYAFQGSYKNEFEGLKF--ERDEIGGS-LNY--ISGEEILRNKFHVDMS- 602
+ Y S RY F NEF G F + G + NY +GEE L K +D+S
Sbjct: 565 LSWLQYFSIPRYGFTALQHNEFLGQNFCPGLNATGNNPCNYATCTGEEYL-VKQGIDLSP 623
Query: 603 YSKWVDLGVLLGMIVLYRVV 622
+ W + L MIV++ +
Sbjct: 624 WGLWKNHVALACMIVIFLTI 643
>ABG8_HUMAN (Q9H221) ATP-binding cassette, sub-family G, member 8
(Sterolin-2)
Length = 673
Score = 232 bits (591), Expect = 3e-60
Identities = 180/595 (30%), Positives = 297/595 (49%), Gaps = 46/595 (7%)
Query: 51 LQGLTGYAKPAQLLAIMGPSGCGKSTLLDALAGRLGSNTRQSGDILINGNKQA--LAYGT 108
+Q L+ + Q+LAI+G SGCG+++LLD + GR +SG I ING + L
Sbjct: 88 IQNLSFKVRSGQMLAIIGSSGCGRASLLDVITGRGHGGKIKSGQIWINGQPSSPQLVRKC 147
Query: 109 SAYVTQDDTLLTTLTVKEAVYYSAQLQLPDTMSNEEKKERADFTIREMGLQDAINTRIGG 168
A+V Q + LL LTV+E + + AQ++LP T S ++ +R + I E+ L+ +TR+G
Sbjct: 148 VAHVRQHNQLLPNLTVRETLAFIAQMRLPRTFSQAQRDKRVEDVIAELRLRQCADTRVGN 207
Query: 169 WGVKGISGGQKRRVSISIEILTRPRLLFLDEPTSGLDSAASYYVMKRIASLDKKDGIQRT 228
V+G+SGG++RRVSI +++L P +L LDEPTSGLDS ++ ++K ++ L K + R
Sbjct: 208 MYVRGLSGGERRRVSIGVQLLWNPGILILDEPTSGLDSFTAHNLVKTLSRLAKGN---RL 264
Query: 229 IVASIHQPSTEVFQLFHNLCLLSSGKTVYFGPASAASEFFASNGFPCPPLQNPSDHLLKT 288
++ S+HQP +++F+LF + L++SG +Y G A ++F + G+PCP NP+D +
Sbjct: 265 VLISLHQPRSDIFRLFDLVLLMTSGTPIYLGAAQHMVQYFTAIGYPCPRYSNPADFYVDL 324
Query: 289 INKDFDQDIEMDLS------ETGTISIEQAIDILVSSYSSSERNQEIKNEVSVLSIVLSL 342
+ D + E +L+ + +E+ D+ + +++ + V S V L
Sbjct: 325 TSID-RRSREQELATREKAQSLAALFLEKVRDL--DDFLWKAETKDLDEDTCVESSVTPL 381
Query: 343 KDNNSTYKKKHAGFLNQCLVLTRRSFVNMFRDLGYYWLRLGIYIALAISLATVFNDLDKS 402
N K G + Q L RR N FRDL L I+ A A ++ L
Sbjct: 382 DTNCLPSPTKMPGAVQQFTTLIRRQISNDFRDLP----TLLIHGAEACLMSMTIGFLYFG 437
Query: 403 NGSIQ----DRGSLLMFVFSFLTFMTIGGFPS--YVEDMKVFERERLNGHYGVTAYVIGN 456
+GSIQ D +LL + + + F I S Y E ++ E +G Y Y
Sbjct: 438 HGSIQLSFMDTAALLFMIGALIPFNVILDVISKCYSERAMLY-YELEDGLYTTGPYFFAK 496
Query: 457 TLSAIP----YLLMISLIPGAIAYYPPGLQKGFEHFIYFICALFSCLMLVESLMMIVASI 512
L +P Y+++ + +A PGLQ HF+ +F C ++ + A++
Sbjct: 497 ILGELPEHCAYIIIYGMPTYWLANLRPGLQPFLLHFLLVWLVVFCCRIMA----LAAAAL 552
Query: 513 VPDFLMGIITGAGIQGIMMLAGGFFRLPNDLPNPFWRYPMFY--ISFHRYAFQGSYKNEF 570
+P F M + LAGGF + L W P + +SF R+ F+G K +F
Sbjct: 553 LPTFHMASFFSNALYNSFYLAGGFMINLSSL----WTVPAWISKVSFLRWCFEGLMKIQF 608
Query: 571 EGLKFERDEIGGSLNYISGEEILRNKFHVDMSYSKW----VDLGVLLGMIVLYRV 621
++ +G +SG++IL + +D SY + + +G+ G +VLY V
Sbjct: 609 SRRTYKM-PLGNLTIAVSGDKIL-SVMELD-SYPLYAIYLIVIGLSGGFMVLYYV 660
>YPC3_CAEEL (Q11180) Putative ABC transporter C05D10.3 in chromosome
III
Length = 598
Score = 227 bits (579), Expect = 7e-59
Identities = 172/604 (28%), Positives = 299/604 (49%), Gaps = 44/604 (7%)
Query: 48 KSILQGLTGYAKPAQLLAIMGPSGCGKSTLLDALAGRLGSNTRQSGDILING---NKQAL 104
K IL ++G A+ +LLAI+G SG GK+TL++ L R +N G ILI+G NK +
Sbjct: 7 KEILHNVSGMAESGKLLAILGSSGAGKTTLMNVLTSRNLTNLDVQGSILIDGRRANKWKI 66
Query: 105 AYGTSAYVTQDDTLLTTLTVKEAVYYSAQLQLPDTM-SNEEKKERADFTIREMGLQDAIN 163
SA+V Q D + T+T +E + + A+L++ D S+ E++ R + + +MGL+ +
Sbjct: 67 RE-MSAFVQQHDMFVGTMTAREHLQFMARLRMGDQYYSDHERQLRVEQVLTQMGLKKCAD 125
Query: 164 TRIGGWG-VKGISGGQKRRVSISIEILTRPRLLFLDEPTSGLDSAASYYVMKRIASLDKK 222
T IG +KG+S G+K+R+S + EILT P++LF DEPTSGLD+ + +V++ + SL
Sbjct: 126 TVIGIPNQLKGLSCGEKKRLSFASEILTCPKILFCDEPTSGLDAFMAGHVVQALRSLADN 185
Query: 223 DGIQRTIVASIHQPSTEVFQLFHNLCLLSSGKTVYFGPASAASEFFASNGFPCPPLQNPS 282
T++ +IHQPS+ V+ LF+N+CL++ G+ +Y GP A F G+PCP NP+
Sbjct: 186 G---MTVIITIHQPSSHVYSLFNNVCLMACGRVIYLGPGDQAVPLFEKCGYPCPAYYNPA 242
Query: 283 DHLLKTINK-DFDQDIEMDLSETGTISIEQAIDILVSSYSSSERNQEI-----KNEVSVL 336
DHL++T+ D D+ M + I + + S++ Q + N++
Sbjct: 243 DHLIRTLAVIDSDRATSM-----------KTISKIRQGFLSTDLGQSVLAIGNANKLRAA 291
Query: 337 SIVLSLKDNNST----YKKKHAGFLNQCLVLTRRSFVNMFRDLGYYWLRLGIYIALAISL 392
S V + T + +A F Q L L RS++ + RD +RL + A
Sbjct: 292 SFVTGSDTSEKTKTFFNQDYNASFWTQFLALFWRSWLTVIRDPNLLSVRLLQILITAFIT 351
Query: 393 ATVFNDLDKSNGSIQDRGSLLMFVFSFLTFM-TIGGFPSYVEDMKVFERERLNGHYGVTA 451
VF + +I ++ + FM P ++ + RE NG Y +A
Sbjct: 352 GIVFFQTPVTPATIISINGIMFNHIRNMNFMLQFPNVPVITAELPIVLRENANGVYRTSA 411
Query: 452 YVIGNTLSAIPYLLMISLIPGAIAYYPPGLQKGFEHFIYFICALFSCLMLVESLMMIVAS 511
Y + ++ +P +++ ++ I Y+ GL F ++ + + S+ VA+
Sbjct: 412 YFLAKNIAELPQYIILPILYNTIVYWMSGLYPNFWNYCFASLVTILITNVAISISYAVAT 471
Query: 512 IV--PDFLMGIITGAGIQGIMMLAGGFFRLPNDLPNPF-WRYPMFYISFHRYAFQGSYKN 568
I D M I+ + +M GGFF + +P+ F W + +S+ +Y ++ N
Sbjct: 472 IFANTDVAMTILPIFVVP--IMAFGGFFITFDAIPSYFKW---LSSLSYFKYGYEALAIN 526
Query: 569 EFEGLKFERDEIGGSLNYISGEEILRNKFHV----DMSYS-KWVDLGVLLGMIVLYRVVF 623
E++ +K + S+ + + +N V D S S K D+ +L GM + R++
Sbjct: 527 EWDSIKVIPECFNSSMTAFALDSCPKNGHQVLESIDFSASHKIFDISILFGMFIGIRIIA 586
Query: 624 LIII 627
+ +
Sbjct: 587 YVAL 590
>ABG1_HUMAN (P45844) ATP-binding cassette, sub-family G, member 1
(White protein homolog) (ATP-binding cassette
transporter 8)
Length = 678
Score = 222 bits (565), Expect = 3e-57
Identities = 171/597 (28%), Positives = 296/597 (48%), Gaps = 39/597 (6%)
Query: 48 KSILQGLTGYAKPAQLLAIMGPSGCGKSTLLDALAGRLGSNTRQSGDILINGNKQALAY- 106
K++L+G++G +L+AIMGPSG GKSTL++ LAG T G +LING + L
Sbjct: 98 KTLLKGISGKFNSGELVAIMGPSGAGKSTLMNILAGY--RETGMKGAVLINGLPRDLRCF 155
Query: 107 -GTSAYVTQDDTLLTTLTVKEAVYYSAQLQLPDTMSNEEKKERADFTIREMGLQDAINTR 165
S Y+ QDD LL LTV+EA+ SA L+L + +E ++E + +GL NTR
Sbjct: 156 RKVSCYIMQDDMLLPHLTVQEAMMVSAHLKLQE--KDEGRREMVKEILTALGLLSCANTR 213
Query: 166 IGGWGVKGISGGQKRRVSISIEILTRPRLLFLDEPTSGLDSAASYYVMKRIASLDKKDGI 225
G +SGGQ++R++I++E++ P ++F DEPTSGLDSA+ + V+ + L +
Sbjct: 214 TGS-----LSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVVSLMKGLAQGG-- 266
Query: 226 QRTIVASIHQPSTEVFQLFHNLCLLSSGKTVYFGPASAASEFFASNGFPCPPLQNPSDHL 285
R+I+ +IHQPS ++F+LF L +LS G+ VY G + G CP NP+D +
Sbjct: 267 -RSIICTIHQPSAKLFELFDQLYVLSQGQCVYRGKVCNLVPYLRDLGLNCPTYHNPADFV 325
Query: 286 LKTINKDF-DQDIEMDLS-ETGTISIEQAIDILVSSYSSSERNQEIKNEVSVLSIVLSLK 343
++ + ++ DQ+ + + G + D+ + + EV + L+
Sbjct: 326 MEVASGEYGDQNSRLVRAVREGMCDSDHKRDLGGDAEVNPFLWHRPSEEVKQTKRLKGLR 385
Query: 344 DNNSTYKKKH---AGFLNQCLVLTRRSFVNMFRDLGYYWLRLGIYIALAISLATVFNDLD 400
++S+ + H A L Q +L +R+F+++ RD LR+ +I + + + ++ +
Sbjct: 386 KDSSSMEGCHSFSASCLTQFCILFKRTFLSIMRDSVLTHLRITSHIGIGLLIGLLYLGIG 445
Query: 401 KSNGSIQDRGSLLMFVFSFLTFM----TIGGFPSYVEDMKVFERERLNGHYGVTAYVIGN 456
+ L F FL F T+ FP +M VF RE LN Y + AY +
Sbjct: 446 NEAKKVLSNSGFLFFSMLFLMFAALMPTVLTFPL---EMGVFLREHLNYWYSLKAYYLAK 502
Query: 457 TLSAIPYLLMISLIPGAIAYYPPGLQKGFEHFIYFICALFSCLMLVESLMMIVASIVPDF 516
T++ +P+ +M + +I Y+ F+ F ++ +SL +++ +
Sbjct: 503 TMADVPFQIMFPVAYCSIVYWMTSQPSDAVRFVLFAALGTMTSLVAQSLGLLIGAASTSL 562
Query: 517 LMGIITGAGIQGIMMLAGGFFRLPNDLPNPFWRYPMFYISFHRYAFQG----SYKNEFEG 572
+ G ++L GFF + +P + M YIS+ RY F+G Y + E
Sbjct: 563 QVATFVGPVTAIPVLLFSGFFVSFDTIPT--YLQWMSYISYVRYGFEGVILSIYGLDRED 620
Query: 573 LKFERDEIGGSLNYISGEEILRNKFHVDMSYSK-WVDLGVLLGMIVLYRVVFLIIIK 628
L + DE + ++ E ILR +D+ +K ++D VL + R++ +++
Sbjct: 621 LHCDIDE---TCHFQKSEAILR---ELDVENAKLYLDFIVLGIFFISLRLIAYFVLR 671
>ABG8_RAT (P58428) ATP-binding cassette, sub-family G, member 8
(Sterolin-2)
Length = 694
Score = 218 bits (555), Expect = 4e-56
Identities = 151/530 (28%), Positives = 260/530 (48%), Gaps = 16/530 (3%)
Query: 51 LQGLTGYAKPAQLLAIMGPSGCGKSTLLDALAGRLGSNTRQSGDILINGNKQA--LAYGT 108
++ L+ + Q+LAI+G +GCG++TLLD + GR +SG I ING L
Sbjct: 110 IRNLSFKVRSGQMLAIIGSAGCGRATLLDVITGRDHGGKMKSGQIWINGQPSTPQLIQKC 169
Query: 109 SAYVTQDDTLLTTLTVKEAVYYSAQLQLPDTMSNEEKKERADFTIREMGLQDAINTRIGG 168
A+V Q D LL LTV+E + + AQ++LP T S ++ +R + I E+ L+ NTR+G
Sbjct: 170 VAHVRQQDQLLPNLTVRETLTFIAQMRLPKTFSQAQRDKRVEDVIAELRLRQCANTRVGN 229
Query: 169 WGVKGISGGQKRRVSISIEILTRPRLLFLDEPTSGLDSAASYYVMKRIASLDKKDGIQRT 228
V+G+SGG++RRVSI +++L P +L LDEPTSGLDS ++ +++ ++ L K + R
Sbjct: 230 TYVRGVSGGERRRVSIGVQLLWNPGILILDEPTSGLDSFTAHNLVRTLSRLAKGN---RL 286
Query: 229 IVASIHQPSTEVFQLFHNLCLLSSGKTVYFGPASAASEFFASNGFPCPPLQNPSDHLLKT 288
++ S+HQP +++F+LF + L++SG +Y G A ++F S G+PCP NP+D +
Sbjct: 287 VLISLHQPRSDIFRLFDLVLLMTSGTPIYLGVAQHMVQYFTSIGYPCPRYSNPADFYVDL 346
Query: 289 INKDFDQDIEMDLSETGTISIEQAIDI-LVSSYSSSERNQEIKN-EVSVLSIVLSL-KDN 345
+ D + E +++ + A+ + V + E K+ + ++ +L +D
Sbjct: 347 TSID-RRSKEQEVATMEKARLLAALFLEKVQGFDDFLWKAEAKSLDTGTYAVSQTLTQDT 405
Query: 346 NSTYKKKHAGFLNQCLVLTRRSFVNMFRDLGYYWLRLGIYIALAISLATVFNDLDKSNGS 405
N + G + Q L RR N FRDL ++ +++ + ++ S
Sbjct: 406 NCGTAAELPGMIQQFTTLIRRQISNDFRDLPTLFIHGAEACLMSLIIGFLYYGHADKPLS 465
Query: 406 IQDRGSLLMFVFSFLTFMTIGGFPSYV-EDMKVFERERLNGHYGVTAYVIGNTLSAIPYL 464
D +LL + + + F I S + + E +G Y Y L +P
Sbjct: 466 FMDMAALLFMIGALIPFNVILDVVSKCHSERSLLYYELEDGLYTAGPYFFAKVLGELPEH 525
Query: 465 LMISLIPGAIAYYPPGLQKGFEHFIYFICALFSCLMLVESLMMIVASIVPDFLMGIITGA 524
+I G Y+ L+ G E F+ L+ + ++ + ++++P F M
Sbjct: 526 CAYVIIYGMPIYWLTNLRPGPELFLLHFMLLWLVVFCCRTMALAASAMLPTFHMSSFCCN 585
Query: 525 GIQGIMMLAGGFFRLPNDLPNPFWRYPMFY--ISFHRYAFQGSYKNEFEG 572
+ L GF N+L W P + +SF R+ F G + +F G
Sbjct: 586 ALYNSFYLTAGFMINLNNL----WIVPAWISKMSFLRWCFSGLMQIQFNG 631
>WHIT_DROME (P10090) White protein
Length = 687
Score = 213 bits (541), Expect = 2e-54
Identities = 164/541 (30%), Positives = 278/541 (51%), Gaps = 46/541 (8%)
Query: 48 KSILQGLTGYAKPAQLLAIMGPSGCGKSTLLDALAGRL--GSNTRQSGDILINGN----K 101
K +L+ + G A P +LLA+MG SG GK+TLL+ALA R G SG L+NG K
Sbjct: 110 KHLLKNVCGVAYPGELLAVMGSSGAGKTTLLNALAFRSPQGIQVSPSGMRLLNGQPVDAK 169
Query: 102 QALAYGTSAYVTQDDTLLTTLTVKEAVYYSAQLQLPDTMSNEEKKERADFTIREMGLQDA 161
+ A AYV QDD + +LT +E + + A +++P ++ ++ R D I+E+ L
Sbjct: 170 EMQA--RCAYVQQDDLFIGSLTAREHLIFQAMVRMPRHLTYRQRVARVDQVIQELSLSKC 227
Query: 162 INTRIGGWG-VKGISGGQKRRVSISIEILTRPRLLFLDEPTSGLDSAASYYVMKRIASLD 220
+T IG G VKG+SGG+++R++ + E LT P LL DEPTSGLDS ++ V++ + L
Sbjct: 228 QHTIIGVPGRVKGLSGGERKRLAFASEALTDPPLLICDEPTSGLDSFTAHSVVQVLKKLS 287
Query: 221 KKDGIQRTIVASIHQPSTEVFQLFHNLCLLSSGKTVYFGPASAASEFFASNGFPCPPLQN 280
+K +T++ +IHQPS+E+F+LF + L++ G+ + G S A +FF+ G CP N
Sbjct: 288 QKG---KTVILTIHQPSSELFELFDKILLMAEGRVAFLGTPSEAVDFFSYVGAQCPTNYN 344
Query: 281 PSDHLLKTINKDFDQDIEMDLSETGTISIEQAIDILVSSYSSSERNQEIKNEVSVLSIVL 340
P+D ++ + ++IE I + +++ S+ ++++ ++ ++
Sbjct: 345 PADFYVQVLAVVPGREIES----------RDRIAKICDNFAISKVARDMEQLLATKNLEK 394
Query: 341 SLKDNNSTYKKKHAGFLNQCLVLTRRSFVNMFRDLGYYWLRLGIYIALAISLATVFNDLD 400
L+ + Y K F+ VL RS++++ ++ +RL +AI + +F
Sbjct: 395 PLEQPENGYTYKATWFMQFRAVLW-RSWLSVLKEPLLVKVRLIQTTMVAILIGLIFLGQQ 453
Query: 401 KSN-GSIQDRGSLLMFVFSFL---TFMTIGGFPSYVEDMKVFERERLNGHYGVTAYVIGN 456
+ G + G++ +F+ + F TI F S ++ VF RE + Y Y +G
Sbjct: 454 LTQVGVMNINGAIFLFLTNMTFQNVFATINVFTS---ELPVFMREARSRLYRCDTYFLGK 510
Query: 457 TLSAIPYLLMISLIPGAIAYYPPGLQKGFEHFIYFICALFSCLMLV-------ESLMMIV 509
T++ +P L + L+ AIAY GL+ G HF F+CL LV S ++
Sbjct: 511 TIAELPLFLTVPLVFTAIAYPMIGLRAGVLHF-------FNCLALVTLVANVSTSFGYLI 563
Query: 510 ASIVPDFLMGIITGAGIQGIMMLAGGFFRLPNDLPNPFWRYPMFYISFHRYAFQGSYKNE 569
+ M + G + +L GGFF N P + + Y+S+ RYA +G N+
Sbjct: 564 SCASSSTSMALSVGPPVIIPFLLFGGFFL--NSGSVPVYLKWLSYLSWFRYANEGLLINQ 621
Query: 570 F 570
+
Sbjct: 622 W 622
>SCRT_DROME (P45843) Scarlet protein
Length = 666
Score = 209 bits (531), Expect = 2e-53
Identities = 161/571 (28%), Positives = 272/571 (47%), Gaps = 47/571 (8%)
Query: 23 EKGVCLTWKDLWVTVSASTGKTNESKSILQGLTGYAKPAQLLAIMGPSGCGKSTLLDALA 82
E+G L W+DL V + G K I+ TG +P L+A+MG SG GK+TL+ LA
Sbjct: 64 EQGATLVWRDLCVYTNVG-GSGQRMKRIINNSTGAIQPGTLMALMGSSGSGKTTLMSTLA 122
Query: 83 GRLGSNTRQSGDILINGNKQA-LAYGTSAYVTQDDTLLTTLTVKEAVYYSAQLQLPDTMS 141
R + T GDILING + + YV QDD L +++V E + + A L+L +S
Sbjct: 123 FRQPAGTVVQGDILINGRRIGPFMHRNHGYVYQDDLFLGSVSVLEHLNFMAHLRLDRRVS 182
Query: 142 NEEKKERADFTIREMGLQDAINTRIG-GWGVKGISGGQKRRVSISIEILTRPRLLFLDEP 200
EE++ + GL A TRIG G K +SGG+++R++ ++E+L P +LF DEP
Sbjct: 183 KEERRLIIKELLERTGLLSAAQTRIGSGDDKKVLSGGERKRLAFAVELLNNPVILFCDEP 242
Query: 201 TSGLDSAASYYVMKRIASLDKKDGIQRTIVASIHQPSTEVFQLFHNLCLLSSGKTVYFGP 260
T+GLDS ++ ++ + L +K TI+ +IHQPS+++F F+N+ LL+ G+ + G
Sbjct: 243 TTGLDSYSAQQLVATLYELAQKG---TTILCTIHQPSSQLFDNFNNVMLLADGRVAFTGS 299
Query: 261 ASAASEFFASNGFPCPPLQNPSDHLLKTINKDFDQDIEMDLSETGTISIEQAIDILVSSY 320
A FFA++G+ CP NP+D L+ + D + S + D S
Sbjct: 300 PQHALSFFANHGYYCPEAYNPADFLIGVLATD------PGYEQASQRSAQHLCDQFAVSS 353
Query: 321 SSSERNQEIKNEVSVLSIVLSLKDNNSTYKKKHAGFLNQCLVLTRRSFVNMFRDLGYYWL 380
++ +R+ + E+ + + + + + + V+ R+ V + RD WL
Sbjct: 354 AAKQRDMLVNLEIHMAQSG-NFPFDTEVESFRGVAWYKRFHVVWLRAIVTLLRDPTIQWL 412
Query: 381 RLGIYIALAISLATVF-NDLDKSNGSIQDRGSLLMFVFSFLTFMTIGGFPS-YVEDMKVF 438
R IA+A + F + S +Q L + S T+ + + + + +F
Sbjct: 413 RFIQKIAMAFIIGACFAGTTEPSQLGVQAVQGALFIMISENTYHPMYSVLNLFPQGFPLF 472
Query: 439 ERERLNGHYGVTAYVIGNTLSAIPYLLMISLIPGAIAYYPPGLQKGFEHFIYFICALFSC 498
RE +G Y Y N L+ +P +++ LI I Y+ GL+ F + + + A+ C
Sbjct: 473 MRETRSGLYSTGQYYAANILALLPGMIIEPLIFVIICYWLTGLRSTF--YAFGVTAM--C 528
Query: 499 LMLV---------------ESLMMIVASIVPDFLMGIITGAGIQGIMMLAGGFFRLPNDL 543
++LV S+ + +A +VP + I M+ G F N L
Sbjct: 529 VVLVMNVATACGCFFSTAFNSVPLAMAYLVP-----------LDYIFMITSGIFIQVNSL 577
Query: 544 PNPFWRYPMFYISFHRYAFQGSYKNEFEGLK 574
P FW ++S+ YA + ++ G++
Sbjct: 578 PVAFWWTQ--FLSWMLYANEAMTAAQWSGVQ 606
>ABG8_MOUSE (Q9DBM0) ATP-binding cassette, sub-family G, member 8
(Sterolin-2)
Length = 673
Score = 209 bits (531), Expect = 2e-53
Identities = 159/591 (26%), Positives = 274/591 (45%), Gaps = 29/591 (4%)
Query: 51 LQGLTGYAKPAQLLAIMGPSGCGKSTLLDALAGRLGSNTRQSGDILINGNKQA--LAYGT 108
++ L+ + Q+LAI+G SGCG+++LLD + GR +SG I ING L
Sbjct: 89 IRNLSFKVRSGQMLAIIGSSGCGRASLLDVITGRGHGGKMKSGQIWINGQPSTPQLVRKC 148
Query: 109 SAYVTQDDTLLTTLTVKEAVYYSAQLQLPDTMSNEEKKERADFTIREMGLQDAINTRIGG 168
A+V Q D LL LTV+E + + AQ++LP T S ++ +R + I E+ L+ NTR+G
Sbjct: 149 VAHVRQHDQLLPNLTVRETLAFIAQMRLPRTFSQAQRDKRVEDVIAELRLRQCANTRVGN 208
Query: 169 WGVKGISGGQKRRVSISIEILTRPRLLFLDEPTSGLDSAASYYVMKRIASLDKKDGIQRT 228
V+G+SGG++RRVSI +++L P +L LDEPTSGLDS ++ ++ ++ L K + R
Sbjct: 209 TYVRGVSGGERRRVSIGVQLLWNPGILILDEPTSGLDSFTAHNLVTTLSRLAKGN---RL 265
Query: 229 IVASIHQPSTEVFQLFHNLCLLSSGKTVYFGPASAASEFFASNGFPCPPLQNPSDHLLKT 288
++ S+HQP +++F+LF + L++SG +Y G A ++F S G PCP NP+D +
Sbjct: 266 VLISLHQPRSDIFRLFDLVLLMTSGTPIYLGAAQQMVQYFTSIGHPCPRYSNPADFYVDL 325
Query: 289 INKDFDQDIEMDLSETGTISIEQAIDIL-------VSSYSSSERNQEIKNEVSVLSIVLS 341
+ D E T+ Q++ L + +E+ +S+ L+
Sbjct: 326 TS----IDRRSKEREVATVEKAQSLAALFLEKVQGFDDFLWKAEAKELNTSTHTVSLTLT 381
Query: 342 LKDNNSTYKKKHAGFLNQCLVLTRRSFVNMFRDLGYYWLRLGIYIALAISLATVFNDLDK 401
+D + + G + Q L RR N FRDL + +++ + ++
Sbjct: 382 -QDTDCGTAVELPGMIEQFSTLIRRQISNDFRDLPTLLIHGSEACLMSLIIGFLYYGHGA 440
Query: 402 SNGSIQDRGSLLMFVFSFLTFMTIGGFPSYV-EDMKVFERERLNGHYGVTAYVIGNTLSA 460
S D +LL + + + F I S + + E +G Y Y L
Sbjct: 441 KQLSFMDTAALLFMIGALIPFNVILDVVSKCHSERSMLYYELEDGLYTAGPYFFAKILGE 500
Query: 461 IPYLLMISLIPGAIAYYPPGLQKGFEHFIYFICALFSCLMLVESLMMIVASIVPDFLM-G 519
+P +I Y+ L+ E F+ ++ + ++ + ++++P F M
Sbjct: 501 LPEHCAYVIIYAMPIYWLTNLRPVPELFLLHFLLVWLVVFCCRTMALAASAMLPTFHMSS 560
Query: 520 IITGAGIQGIMMLAGGFFRLPNDLPNPFWRYPMFYISFHRYAFQGSYKNEFEGLKFERDE 579
A + AG L N P W + +SF R+ F G + +F G + +
Sbjct: 561 FFCNALYNSFYLTAGFMINLDNLWIVPAW---ISKLSFLRWCFSGLMQIQFNGHLY-TTQ 616
Query: 580 IGGSLNYISGEEILR----NKFHVDMSYSKWVDLGVLLGMIVLYRVVFLII 626
IG I G+ ++ N + Y + +G+ G + LY + +I
Sbjct: 617 IGNFTFSILGDTMISAMDLNSHPLYAIY--LIVIGISYGFLFLYYLSLKLI 665
>WHIT_LUCCU (Q05360) White protein
Length = 677
Score = 207 bits (528), Expect = 5e-53
Identities = 150/534 (28%), Positives = 271/534 (50%), Gaps = 30/534 (5%)
Query: 48 KSILQGLTGYAKPAQLLAIMGPSGCGKSTLLDALAGRL--GSNTRQSGDILINGN----K 101
K +++ + G A P +LLA+MG SG GK+TLL+ALA R G S ++NG+ K
Sbjct: 99 KHLIKNVCGVAYPGELLAVMGSSGAGKTTLLNALAFRSARGVQISPSSVRMLNGHPVDAK 158
Query: 102 QALAYGTSAYVTQDDTLLTTLTVKEAVYYSAQLQLPDTMSNEEKKERADFTIREMGLQDA 161
+ A AYV QDD + +LT +E + + A +++P TM+ ++K +R D I+++ L
Sbjct: 159 EMQA--RCAYVQQDDLFIGSLTAREHLIFQATVRMPRTMTQKQKLQRVDQVIQDLSLIKC 216
Query: 162 INTRIGGWG-VKGISGGQKRRVSISIEILTRPRLLFLDEPTSGLDSAASYYVMKRIASLD 220
NT IG G VKG+SGG+++R++ + E LT P LL DEPTSGLDS + V++ + L
Sbjct: 217 QNTIIGVPGRVKGLSGGERKRLAFASEALTDPPLLICDEPTSGLDSFMAASVVQVLKKLS 276
Query: 221 KKDGIQRTIVASIHQPSTEVFQLFHNLCLLSSGKTVYFGPASAASEFFASNGFPCPPLQN 280
++ +T++ +IHQPS+E+F+LF + L++ G+ + G A +FF+ G CP N
Sbjct: 277 QRG---KTVILTIHQPSSELFELFDKILLMAEGRVAFLGTPVEAVDFFSFIGAQCPTNYN 333
Query: 281 PSDHLLKTINKDFDQDIEMDLSETGTISIEQAIDILVSSYSSSERNQEIKNEVSVLSIVL 340
P+D ++ + ++IE I + +++ + ++E++ ++
Sbjct: 334 PADFYVQVLAVVPGREIES----------RDRISKICDNFAVGKVSREMEQNFQKIAAKT 383
Query: 341 S--LKDNNSTYKKKHAGFLNQCLVLTRRSFVNMFRDLGYYWLRLGIYIALAISLATVFND 398
KD+ +T K A + Q + RS+++ ++ +RL +A+ + +F +
Sbjct: 384 DGLQKDDETTILYK-ASWFTQFRAIMWRSWISTLKEPLLVKVRLIQTTMVAVLIGLIFLN 442
Query: 399 LDKSNGSIQDRGSLLMFVFSFLTFMTIGGFPS-YVEDMKVFERERLNGHYGVTAYVIGNT 457
+ + + + + +TF + + + ++ VF RE + Y Y +G T
Sbjct: 443 QPMTQVGVMNINGAIFLFLTNMTFQNVFAVINVFTSELPVFMRETRSRLYRCDTYFLGKT 502
Query: 458 LSAIPYLLMISLIPGAIAYYPPGLQKGFEHFIYFICALFSCLMLVESLMMIVASIVPDFL 517
L+ +P L++ + AIAY GL+ G HF+ + + + S +++
Sbjct: 503 LAELPLFLVVPFLFIAIAYPMIGLRPGITHFLSALALVTLVANVSTSFGYLISCASTSTS 562
Query: 518 MGIITGAGIQGIMMLAGGFFRLPNDLPNPF-WRYPMFYISFHRYAFQGSYKNEF 570
M + G + +L GG F +P F W + Y S+ RYA +G N++
Sbjct: 563 MALSVGPPLTIPFLLFGGVFLNSGSVPVYFKW---LSYFSWFRYANEGLLINQW 613
>WHIT_CERCA (Q17320) White protein
Length = 679
Score = 207 bits (527), Expect = 7e-53
Identities = 154/537 (28%), Positives = 270/537 (49%), Gaps = 29/537 (5%)
Query: 48 KSILQGLTGYAKPAQLLAIMGPSGCGKSTLLDALAGRLGSNTRQSGDIL--INGN----K 101
K +L+ +G A P +LLA+MG SG GK+TLL+A A R + S + +NG+ K
Sbjct: 101 KHLLKNDSGVAYPGELLAVMGSSGAGKTTLLNASAFRSSKGVQISPSTIRMLNGHPVDAK 160
Query: 102 QALAYGTSAYVTQDDTLLTTLTVKEAVYYSAQLQLPDTMSNEEKKERADFTIREMGLQDA 161
+ A AYV QDD + +LT +E + + A +++P M+ ++K +R D I+++ L
Sbjct: 161 EMQA--RCAYVQQDDLFIGSLTAREHLIFQAMVRMPRHMTQKQKVQRVDQVIQDLSLGKC 218
Query: 162 INTRIGGWG-VKGISGGQKRRVSISIEILTRPRLLFLDEPTSGLDSAASYYVMKRIASLD 220
NT IG G VKG+SGG+++R++ + E LT P LL DEPTSGLDS ++ V++ + L
Sbjct: 219 QNTLIGVPGRVKGLSGGERKRLAFASEALTDPPLLICDEPTSGLDSFMAHSVVQVLKKLS 278
Query: 221 KKDGIQRTIVASIHQPSTEVFQLFHNLCLLSSGKTVYFGPASAASEFFASNGFPCPPLQN 280
+K +T++ +IHQPS+E+F+LF + L++ G+ + G A +FF+ G CP
Sbjct: 279 QKG---KTVILTIHQPSSELFELFDKILLMAEGRVAFLGTPGEAVDFFSYIGATCPTNYT 335
Query: 281 PSDHLLKTINKDFDQDIEMDLSETGTISIEQAIDILVSSYSSSERNQEIKNEVSVLSIVL 340
P+D ++ + +++E + + D S E Q + V S
Sbjct: 336 PADFYVQVLAVVPGREVE------SRDRVAKICDNFAVGKVSREMEQNFQKLVK--SNGF 387
Query: 341 SLKDNNS-TYKKKHAGFLNQCLVLTRRSFVNMFRDLGYYWLRLGIYIALAISLATVFNDL 399
+D N TYK A + Q + RS++++ ++ +RL +A+ + +F
Sbjct: 388 GKEDENEYTYK---ASWFMQFRAVLWRSWLSVLKEPLLVKVRLLQTTMVAVLIGLIFLGQ 444
Query: 400 DKSN-GSIQDRGSLLMFVFSFLTFMTIGGFPSYVEDMKVFERERLNGHYGVTAYVIGNTL 458
+ G + G++ +F+ + + + ++ VF RE + Y Y +G T+
Sbjct: 445 QLTQVGVMNINGAIFLFLTNMTFQNSFATITVFTTELPVFMRETRSRLYRCDTYFLGKTI 504
Query: 459 SAIPYLLMISLIPGAIAYYPPGLQKGFEHFIYFICALFSCLMLVESLMMIVASIVPDFLM 518
+ +P L++ + AIAY GL+ G +HF + + + S +++ M
Sbjct: 505 AELPLFLVVPFLFTAIAYPLIGLRPGVDHFFTALALVTLVANVSTSFGYLISCACSSTSM 564
Query: 519 GIITGAGIQGIMMLAGGFFRLPNDLPNPF-WRYPMFYISFHRYAFQGSYKNEFEGLK 574
+ G + +L GGFF +P F W + Y+S+ RYA +G N++ +K
Sbjct: 565 ALSVGPPVIIPFLLFGGFFLNSGSVPVYFKW---LSYLSWFRYANEGLLINQWADVK 618
>ABG4_HUMAN (Q9H172) ATP-binding cassette, sub-family G, member 4
Length = 646
Score = 207 bits (527), Expect = 7e-53
Identities = 149/523 (28%), Positives = 257/523 (48%), Gaps = 33/523 (6%)
Query: 48 KSILQGLTGYAKPAQLLAIMGPSGCGKSTLLDALAGRLGSNTRQSGDILINGNKQALAY- 106
K++L+ L+G +L+ IMGPSG GKST ++ LAG S + G IL+NG + L
Sbjct: 82 KTLLKCLSGKFCRRELIGIMGPSGAGKSTFMNILAGYRESGMK--GQILVNGRPRELRTF 139
Query: 107 -GTSAYVTQDDTLLTTLTVKEAVYYSAQLQLPDTMSNEEKKERADFTIREMGLQDAINTR 165
S Y+ QDD LL LTV EA+ SA L+L + E KKE + +GL +TR
Sbjct: 140 RKMSCYIMQDDMLLPHLTVLEAMMVSANLKLSE--KQEVKKELVTEILTALGLMSCSHTR 197
Query: 166 IGGWGVKGISGGQKRRVSISIEILTRPRLLFLDEPTSGLDSAASYYVMKRIASLDKKDGI 225
+SGGQ++R++I++E++ P ++F DEPTSGLDSA+ + V+ + SL +
Sbjct: 198 TAL-----LSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVVSLMKSLAQGG-- 250
Query: 226 QRTIVASIHQPSTEVFQLFHNLCLLSSGKTVYFGPASAASEFFASNGFPCPPLQNPSDHL 285
RTI+ +IHQPS ++F++F L +LS G+ ++ G + + G CP NP+D +
Sbjct: 251 -RTIICTIHQPSAKLFEMFDKLYILSQGQCIFKGVVTNLIPYLKGLGLHCPTYHNPADFI 309
Query: 286 LKTINKDFDQDIEMDLSETGTISIEQAIDILVSSYSSSERNQEIKNEVSVLSIVLSLKDN 345
++ + ++ DL+ +++ + + SS E KNEV + +
Sbjct: 310 IEVASGEYG-----DLNPMLFRAVQNGLCAMAEKKSSPE-----KNEVPAPCPPCPPEVD 359
Query: 346 NSTYKKKHAGFLNQCLVLTRRSFVNMFRDLGYYWLRLGIYIALAISLATVFNDLDKSNGS 405
L Q +L +R+F+++ RD LR ++ + + + ++ +
Sbjct: 360 PIESHTFATSTLTQFCILFKRTFLSILRDTVLTHLRFMSHVVIGVLIGLLYLHIGDDASK 419
Query: 406 IQDRGSLLMFVFSFLTFM----TIGGFPSYVEDMKVFERERLNGHYGVTAYVIGNTLSAI 461
+ + L F FL F T+ FP +M VF RE LN Y + AY + T++ +
Sbjct: 420 VFNNTGCLFFSMLFLMFAALMPTVLTFPL---EMAVFMREHLNYWYSLKAYYLAKTMADV 476
Query: 462 PYLLMISLIPGAIAYYPPGLQKGFEHFIYFICALFSCLMLVESLMMIVASIVPDFLMGII 521
P+ ++ ++ +I Y+ G F+ F + ++ +SL +++ + +
Sbjct: 477 PFQVVCPVVYCSIVYWMTGQPAETSRFLLFSALATATALVAQSLGLLIGAASNSLQVATF 536
Query: 522 TGAGIQGIMMLAGGFFRLPNDLPNPFWRYPMFYISFHRYAFQG 564
G ++L GFF +P + Y+S+ RY F+G
Sbjct: 537 VGPVTAIPVLLFSGFFVSFKTIPT--YLQWSSYLSYVRYGFEG 577
>ABG5_HUMAN (Q9H222) ATP-binding cassette, sub-family G, member 5
(Sterolin-1)
Length = 651
Score = 207 bits (526), Expect = 9e-53
Identities = 149/537 (27%), Positives = 271/537 (49%), Gaps = 24/537 (4%)
Query: 47 SKSILQGLTGYAKPAQLLAIMGPSGCGKSTLLDALAGRLGSNTRQSGDILINGN--KQAL 104
++ IL+ ++ Y + Q++ I+G SG GK+TLLDA++GRLG G++ +NG ++
Sbjct: 65 TRQILKDVSLYVESGQIMCILGSSGSGKTTLLDAMSGRLGRAGTFLGEVYVNGRALRREQ 124
Query: 105 AYGTSAYVTQDDTLLTTLTVKEAVYYSAQLQLPDTMSNEEKKERADFTIREMGLQDAINT 164
+YV Q DTLL++LTV+E ++Y+A L + +K + + + E+ L +
Sbjct: 125 FQDCFSYVLQSDTLLSSLTVRETLHYTALLAIRRGNPGSFQK-KVEAVMAELSLSHVADR 183
Query: 165 RIGGWGVKGISGGQKRRVSISIEILTRPRLLFLDEPTSGLDSAASYYVMKRIASLDKKDG 224
IG + + GIS G++RRVSI+ ++L P+++ DEPT+GLD + ++ + L +++
Sbjct: 184 LIGNYSLGGISTGERRRVSIAAQLLQDPKVMLFDEPTTGLDCMTANQIVVLLVELARRN- 242
Query: 225 IQRTIVASIHQPSTEVFQLFHNLCLLSSGKTVYFGPASAASEFFASNGFPCPPLQNPSDH 284
R +V +IHQP +E+FQLF + +LS G+ ++ G + +FF G+PCP NP D
Sbjct: 243 --RIVVLTIHQPRSELFQLFDKIAILSFGELIFCGTPAEMLDFFNDCGYPCPEHSNPFDF 300
Query: 285 LLKTINKDFDQDIEMDLSETGTIS-IEQAIDILVSSYSSSERNQEIKNEVSVLSIVLSLK 343
+ + D Q E ++ + + IE A + + + + +K+ ++ + K
Sbjct: 301 YMDLTSVD-TQSKEREIETSKRVQMIESAYKKSAICHKTLKNIERMKHLKTLPMVPFKTK 359
Query: 344 DNNSTYKKKHAGFLNQCLVLTRRSFVNMFRDLGYYWLRL--GIYIALAISLATVFNDLDK 401
D+ + K VL RR N+ R+ RL + + L + + +
Sbjct: 360 DSPGVFSKLG--------VLLRRVTRNLVRNKLAVITRLLQNLIMGLFLLFFVLRVRSNV 411
Query: 402 SNGSIQDR-GSLLMFVFSFLTFMTIGGFPSYVEDMKVFERERLNGHYGVTAYVIGNTLSA 460
G+IQDR G L FV + + + V ++E +G Y ++ L
Sbjct: 412 LKGAIQDRVGLLYQFVGATPYTGMLNAVNLFPVLRAVSDQESQDGLYQKWQMMLAYALHV 471
Query: 461 IPYLLMISLIPGAIAYYPPGLQKGFEHFIYFICALFSCLMLVESLMMIVASIV--PDFLM 518
+P+ ++ ++I ++ Y+ GL F YF AL + ++ E L +++ IV P+ +
Sbjct: 472 LPFSVVATMIFSSVCYWTLGLHPEVARFGYFSAALLAPHLIGEFLTLVLLGIVQNPNIVN 531
Query: 519 GIITGAGIQGIMMLAGGFFRLPNDLPNPFWRYPMFYISFHRYAFQGSYKNEFEGLKF 575
++ I G+ ++ GF R ++P PF + Y +F +Y + NEF GL F
Sbjct: 532 SVVALLSIAGV-LVGSGFLRNIQEMPIPF--KIISYFTFQKYCSEILVVNEFYGLNF 585
>YOH5_YEAST (Q08234) Probable ATP-dependent transporter
YOL074C/YOL075C
Length = 1294
Score = 205 bits (522), Expect = 3e-52
Identities = 170/606 (28%), Positives = 287/606 (47%), Gaps = 45/606 (7%)
Query: 45 NESKSILQGLTGYAKPAQLLAIMGPSGCGKSTLLDALAGRLGSNT----RQSGDILINGN 100
+E+K ILQ + KP + AIMGPSG GKS+LL+ ++GRL S+ SG I+ N
Sbjct: 704 HETKEILQSVNAIFKPGMINAIMGPSGSGKSSLLNLISGRLKSSVFAKFDTSGSIMFNDI 763
Query: 101 K--QALAYGTSAYVTQDDT-LLTTLTVKEAVYYSAQLQLPDTMSNEEKKERADFTIREMG 157
+ + + +YV+QDD LL LTVKE + Y+A L+L ++ E+ ER D IR +G
Sbjct: 764 QVSELMFKNVCSYVSQDDDHLLAALTVKETLKYAAALRLHH-LTEAERMERTDNLIRSLG 822
Query: 158 LQDAINTRIGGWGVKGISGGQKRRVSISIEILTRPRLLFLDEPTSGLDSAASYYVMKRIA 217
L+ N IG VKGISGG+KRRV++ +++L P +L LDEPTSGLDS S +++ +
Sbjct: 823 LKHCENNIIGNEFVKGISGGEKRRVTMGVQLLNDPPILLLDEPTSGLDSFTSATILEILE 882
Query: 218 SLDKKDGIQRTIVASIHQPSTEVFQLFHNLCLLS-SGKTVYFGPASAASEFFASNGFPCP 276
L ++ G +TI+ +IHQP +E+F+ F N+ LL+ SG+T + G +F G+ CP
Sbjct: 883 KLCREQG--KTIIITIHQPRSELFKRFGNVLLLAKSGRTAFNGSPDEMIAYFTELGYNCP 940
Query: 277 PLQNPSDHLLKTINKDFDQDIEMDLSETGTISIEQAIDILVSSYSSSERNQEI------- 329
N +D L I+ + +E IS ++ ++S++ ++ N+ +
Sbjct: 941 SFTNVADFFLDLISVNTQ-------NEQNEISSRARVEKILSAWKANMDNESLSPTPISE 993
Query: 330 KNEVSVLSIVLSLKDNNSTYKKKHAGFLNQCLVLTRRSFVNMFRDLGYYWLRLGIYIALA 389
K + S S S + +K A + +V +R F R R+ L
Sbjct: 994 KQQYSQESFFTEY----SEFVRKPANLVLAYIVNVKRQFTTTRRSFDSLMARIAQIPGLG 1049
Query: 390 ISLATVFNDLDKSNGSIQDRGSLLMFVFSFLTFMTIGGFPSYVEDMKVFERERLNGHYGV 449
+ A F + + SI +R L + +G Y + F E + YG+
Sbjct: 1050 VIFALFFAPVKHNYTSISNRLGLAQESTALYFVGMLGNLACYPTERDYFYEEYNDNVYGI 1109
Query: 450 TAYVIGNTLSAIPYLLMISLIPGAIAYYPPGLQKGFEHFIYFICALFSCLMLVESLMMIV 509
+ + +P + S++ GL + +F + F E L ++
Sbjct: 1110 APFFLAYMTLELPLSALASVLYAVFTVLACGLPRTAGNFFATVYCSFIVTCCGERLGIMT 1169
Query: 510 ASIV--PDFLMGIIT-----GAGIQGIMMLAGGFFRLPNDLPNPFWRYPMFYISFHRYAF 562
+ P F++ I+ G + G+M L + NP M I+F AF
Sbjct: 1170 NTFFERPGFVVNCISIILSIGTQMSGLMSLGMSRVLKGFNYLNPVGYTSMIIINF---AF 1226
Query: 563 QGSYKNEFEGLKFERDEIGGSLNYISGEEILRNKFHVDMSYSKWVDLGVLLGMIVLYRVV 622
G+ K E D G+ + +G ++L + + + + K+ LG+++ + ++YR++
Sbjct: 1227 PGNLKLTCEDGGKNSD---GTCEFANGHDVLVS-YGLVRNTQKY--LGIIVCVAIIYRLI 1280
Query: 623 FLIIIK 628
I+K
Sbjct: 1281 AFFILK 1286
Score = 187 bits (476), Expect = 6e-47
Identities = 144/527 (27%), Positives = 248/527 (46%), Gaps = 46/527 (8%)
Query: 63 LLAIMGPSGCGKSTLLDALAGRLGSNTRQSGDIL-------------------INGNKQA 103
++A+MG SG GK+TLL+ LA ++ +G I ++G
Sbjct: 57 VMAVMGGSGSGKTTLLNVLASKISGGLTHNGSIRYVLEDTGSEPNETEPKRAHLDGQDHP 116
Query: 104 LA-YGTSAYVTQDDTLLTTLTVKEAVYYSAQLQLPDTMSNEEKKERADFTIREMGLQDAI 162
+ + AY+ Q D L LT +E + ++A L+L S KK + I E+GL+D
Sbjct: 117 IQKHVIMAYLPQQDVLSPRLTCRETLKFAADLKL--NSSERTKKLMVEQLIEELGLKDCA 174
Query: 163 NTRIGGWGVKGISGGQKRRVSISIEILTRPRLLFLDEPTSGLDSAASYYVMKRIASLDKK 222
+T +G +G+SGG+KRR+SI ++++ P ++FLDEPT+GLD+ +++ V+K + L K+
Sbjct: 175 DTLVGDNSHRGLSGGEKRRLSIGTQMISNPSIMFLDEPTTGLDAYSAFLVIKTLKKLAKE 234
Query: 223 DGIQRTIVASIHQPSTEVFQLFHNLCLLSSGKTVYFGPASAASEFFASNGFPCPPLQNPS 282
DG RT + SIHQP +++ L +C+LS G VY +F S G+ P L NP+
Sbjct: 235 DG--RTFIMSIHQPRSDILFLLDQVCILSKGNVVYCDKMDNTIPYFESIGYHVPQLVNPA 292
Query: 283 DHLLKTINKDFDQDIEMDLSETGTISIEQAIDILVSSYSSSERNQEIKNEVSVLSIVLSL 342
D+ + + D D E E T + ++ L+ + ER S +S +
Sbjct: 293 DYFIDLSSVDSRSDKE----EAAT---QSRLNSLIDHWHDYERTHLQLQAESYISNATEI 345
Query: 343 KDNNSTYKKKHAGFLNQCLVLTRRSFVNMFRDLGYYWLRLGIYIALAISLATVFNDLDKS 402
+ N T + F Q VLTRR+F F D + + ++ DKS
Sbjct: 346 QIQNMTTR---LPFWKQVTVLTRRNFKLNFSDYVTLISTFAEPLIIGTVCGWIYYKPDKS 402
Query: 403 N-GSIQDR-----GSLLMFVFSFLTFMTIGGFPSYVEDMKVFERERLNGHYGVTAYVIGN 456
+ G ++ S ++ + +L F T + +D+ +++RER G A+++
Sbjct: 403 SIGGLRTTTACLYASTILQCYLYLLFDT---YRLCEQDIALYDRERAEGSVTPLAFIVAR 459
Query: 457 TLSA-IPYLLMISLIPGAIAYYPPGLQKGFEHFIYFICALFSCLMLVESLMMIVASIVPD 515
+S + +++I +I Y+ GL+ F Y +F C + L M+ ++ D
Sbjct: 460 KISLFLSDDFAMTMIFVSITYFMFGLEADARKFFYQFAVVFLCQLSCSGLSMLSVAVSRD 519
Query: 516 FLMGIITGAGIQGIMMLAGGFFRLPNDLPNPFWRYPMFYISFHRYAF 562
F + G ++ + GFF N P + + YI+F Y+F
Sbjct: 520 FSKASLVGNMTFTVLSMGCGFF--VNAKVMPVYVRWIKYIAFTWYSF 564
>WHIT_ANOGA (Q27256) White protein
Length = 695
Score = 203 bits (517), Expect = 1e-51
Identities = 158/598 (26%), Positives = 297/598 (49%), Gaps = 35/598 (5%)
Query: 45 NESKSILQGLTGYAKPAQLLAIMGPSGCGKSTLLDALAGRLGSNTRQSGDIL--ING--- 99
N K +L+ +TG AK +LLA+MG SG GK+TLL+ALA R + S + + +NG
Sbjct: 110 NPRKHLLKNVTGVAKSGELLAVMGSSGAGKTTLLNALAFRSPPGVKISPNAVRALNGVPV 169
Query: 100 NKQALAYGTSAYVTQDDTLLTTLTVKEAVYYSAQLQLPDTMSNEEKKERADFTIREMGLQ 159
N + L AYV QDD + +LT +E + + A L++ + K+ R ++E+ L
Sbjct: 170 NAEQLR-ARCAYVQQDDLFIPSLTTREHLLFQAMLRMGRDVPASVKQHRVQEVLQELSLV 228
Query: 160 DAINTRIGGWG-VKGISGGQKRRVSISIEILTRPRLLFLDEPTSGLDSAASYYVMKRIAS 218
+T IG G +KG+SGG+++R++ + E LT P LL DEPTSGLDS ++ V++ +
Sbjct: 229 KCADTIIGAPGRIKGLSGGERKRLAFASETLTDPHLLLCDEPTSGLDSFMAHSVLQVLKG 288
Query: 219 LDKKDGIQRTIVASIHQPSTEVFQLFHNLCLLSSGKTVYFGPASAASEFFASNGFPCPPL 278
+ K +TI+ +IHQPS+E++ LF + L++ G+ + G ++EFF+ G PCPP
Sbjct: 289 MAMKG---KTIILTIHQPSSELYCLFDKILLVAEGRVAFLGSPYQSAEFFSQLGIPCPPN 345
Query: 279 QNPSDHLLKTINKDFDQDIEMDLSETGTISIEQAIDILVSSYSSSERNQEIKNEVSVLS- 337
NP+D ++ + ++ I + S++ S +E+ SV
Sbjct: 346 YNPADFYVQM----------LAIAPAKEAECRDMIKKICDSFAVSPIAREVLETASVAGK 395
Query: 338 ------IVLSLKDNNSTYKKKHAGFLNQCLVLTRRSFVNMFRDLGYYWLRLGIYIALAIS 391
++ ++ ST + + + Q + RS++++ +D +RL +A
Sbjct: 396 GMDEPYMLQQVEGVGSTGYR--SSWWTQFYCILWRSWLSVLKDPMLVKVRLLQTAMVATL 453
Query: 392 LATV-FNDLDKSNGSIQDRGSLLMFVFSFLTFMTIGGFPS-YVEDMKVFERERLNGHYGV 449
+ ++ F + +G + GSL +F+ + +TF + + + ++ VF RE+ + Y V
Sbjct: 454 IGSIYFGQVLDQDGVMNINGSLFLFLTN-MTFQNVFAVINVFSAELPVFLREKRSRLYRV 512
Query: 450 TAYVIGNTLSAIPYLLMISLIPGAIAYYPPGLQKGFEHFIYFICALFSCLMLVESLMMIV 509
Y +G T++ +P + + + +I Y GL+ G H++ + + + S ++
Sbjct: 513 DTYFLGKTIAELPLFIAVPFVFTSITYPMIGLRTGATHYLTTLFIVTLVANVSTSFGYLI 572
Query: 510 ASIVPDFLMGIITGAGIQGIMMLAGGFFRLPNDLPNPFWRYPMFYISFHRYAFQGSYKNE 569
+ M + G + ++ GGFF +P +++Y + Y+S+ RYA + N+
Sbjct: 573 SCASSSISMALSVGPPVVIPFLIFGGFFLNSASVP-AYFKY-LSYLSWFRYANEALLINQ 630
Query: 570 FEGLKFERDEIGGSLNYISGEEILRNKFHVDMSYSKWVDLGVLLGMIVLYRVVFLIII 627
+ + + EI+ F+ + +D+ L +IVL+R+ L+ +
Sbjct: 631 WSTVVDGEIACTRANVTCPRSEIILETFNFRVE-DFALDIACLFALIVLFRLGALLCL 687
>ABG5_MOUSE (Q99PE8) ATP-binding cassette, sub-family G, member 5
(Sterolin-1)
Length = 652
Score = 199 bits (507), Expect = 1e-50
Identities = 151/541 (27%), Positives = 265/541 (48%), Gaps = 34/541 (6%)
Query: 48 KSILQGLTGYAKPAQLLAIMGPSGCGKSTLLDALAGRLGSNTRQSGDILINGN--KQALA 105
+ IL+ ++ Y + Q++ I+G SG GK+TLLDA++GRL G++ +NG ++
Sbjct: 67 RQILKDVSLYIESGQIMCILGSSGSGKTTLLDAISGRLRRTGTLEGEVFVNGCELRRDQF 126
Query: 106 YGTSAYVTQDDTLLTTLTVKEAVYYSAQLQLPDTMSNEEKKERADFTIREMGLQDAINTR 165
+YV Q D L++LTV+E + Y+A L L + ++ K + + + E+ L +
Sbjct: 127 QDCFSYVLQSDVFLSSLTVRETLRYTAMLALCRSSADFYNK-KVEAVMTELSLSHVADQM 185
Query: 166 IGGWGVKGISGGQKRRVSISIEILTRPRLLFLDEPTSGLDSAASYYVMKRIASLDKKDGI 225
IG + GIS G++RRVSI+ ++L P+++ LDEPT+GLD + ++ +A L ++D
Sbjct: 186 IGSYNFGGISSGERRRVSIAAQLLQDPKVMMLDEPTTGLDCMTANQIVLLLAELARRD-- 243
Query: 226 QRTIVASIHQPSTEVFQLFHNLCLLSSGKTVYFGPASAASEFFASNGFPCPPLQNPSDHL 285
R ++ +IHQP +E+FQ F + +L+ G+ V+ G FF + G+PCP NP D
Sbjct: 244 -RIVIVTIHQPRSELFQHFDKIAILTYGELVFCGTPEEMLGFFNNCGYPCPEHSNPFDFY 302
Query: 286 LKTINKDFDQDIEMDLSETGTISIEQAIDILVSSYSSSERNQEIKNEVSVLSIVLSLKDN 345
+ + D S I + + +L ++ S+ +I + + +L
Sbjct: 303 MDLTSVDTQ-------SREREIETYKRVQMLECAFKESDIYHKILENIERARYLKTLP-- 353
Query: 346 NSTYKKKH-AGFLNQCLVLTRRSFVNMFRDLGYYWLRLGIYIALAISLATVFNDLDKSN- 403
+K K G + VL RR N+ R+ +RL L + L +F L N
Sbjct: 354 TVPFKTKDPPGMFGKLGVLLRRVTRNLMRNKQAVIMRL--VQNLIMGLFLIFYLLRVQNN 411
Query: 404 ---GSIQDRGSLLMFVFSFLTFM----TIGGFPSYVEDMKVFERERLNGHYGVTAYVIGN 456
G++QDR LL + + + FP V ++E +G Y ++
Sbjct: 412 TLKGAVQDRVGLLYQLVGATPYTGMLNAVNLFPML---RAVSDQESQDGLYHKWQMLLAY 468
Query: 457 TLSAIPYLLMISLIPGAIAYYPPGLQKGFEHFIYFICALFSCLMLVESLMMIVASIV--P 514
L +P+ ++ ++I ++ Y+ GL F YF AL + ++ E L +++ IV P
Sbjct: 469 VLHVLPFSVIATVIFSSVCYWTLGLYPEVARFGYFSAALLAPHLIGEFLTLVLLGIVQNP 528
Query: 515 DFLMGIITGAGIQGIMMLAGGFFRLPNDLPNPFWRYPMFYISFHRYAFQGSYKNEFEGLK 574
+ + I+ I G +++ GF R ++P P + Y +F +Y + NEF GL
Sbjct: 529 NIVNSIVALLSISG-LLIGSGFIRNIQEMPIPL--KILGYFTFQKYCCEILVVNEFYGLN 585
Query: 575 F 575
F
Sbjct: 586 F 586
>ABG3_MOUSE (Q99P81) ATP-binding cassette, sub-family G, member 3
Length = 650
Score = 199 bits (507), Expect = 1e-50
Identities = 178/604 (29%), Positives = 283/604 (46%), Gaps = 50/604 (8%)
Query: 51 LQGLTGYAKPAQLLAIMGPSGCGKSTLLDALAGRLGSNTRQSGDILINGNKQALAYG-TS 109
L ++G KP L AIMGP +S LLD LA R SGDILING + + TS
Sbjct: 64 LSNISGIMKPG-LNAIMGPQDGSRSLLLDVLAARRDPRGL-SGDILINGKPRPANFKCTS 121
Query: 110 AYVTQDDTLLTTLTVKEAVYYSAQLQLPDTMSNEEKKERADFTIREMGLQDAINTRIGGW 169
YV Q+D +L T+TV++ + +SA L+LP T++ +EK+ R + + + L N
Sbjct: 122 GYVPQNDVVLGTVTVRDNLEFSAALRLPVTITRDEKRRRINEVLELLHLNKEQN------ 175
Query: 170 GVKGISGGQKRRVSISIEILTRPRLLFLDEPTSGLDSAASYYVMKRIASLDKKDGIQRTI 229
+K S ++R SI++E++T +LFLD+PT+GLD + V+ + + KK RTI
Sbjct: 176 -IKPRSKELRKRTSIAMELVTEHPILFLDDPTTGLDLRTTTDVILVLRRMSKKG---RTI 231
Query: 230 VASIHQPSTEVFQLFHNLCLLSSGKTVYFGPASAASEFFASNGFPCPPLQNPSDHLLKTI 289
+ SI+QP +F+ F +L L++SGK ++ GPA A E+F S G+ NP+D L I
Sbjct: 232 IFSINQPQYSIFKFFDSLTLVASGKVMFHGPAQDALEYFRSAGYNYESHNNPADFFLDVI 291
Query: 290 NKDFDQ--DIEMDLSETGTIS--IEQAIDI---LVSSYSSSERNQEIKNEVSVLSIVLSL 342
N F D E D E E+ + L + Y+ S E + + L L
Sbjct: 292 NGGFSNILDTEEDGHEDDKYEELFERQYQVTGKLANMYAQSPLYSETRAILDQLLGEQKL 351
Query: 343 KDNNSTYKKKHAGFLNQCLVLTRRSFVNMFRDLGYYW---LRLGIYIALAISLATVFNDL 399
+ +++ F +Q + +SF N G+ W ++ I + LA ++ T F L
Sbjct: 352 ERSSAVETTCVTPFCHQLKWIICQSFKNF---KGFPWVTVIQAIITVILATAVGTAFRVL 408
Query: 400 DKSNGSIQDRGSLLMFVFSFLTFMTIGGFPSYVEDMKVFERERLNGHYGVTAYVIGNTLS 459
+Q R LL + F ++ +V D F E +G+Y V++Y G L+
Sbjct: 409 KNDCIEVQMRAGLLYLLTIFQCITSVSAGELFVIDRVRFLHEHTSGYYRVSSYFFGKLLA 468
Query: 460 -AIPYLLMISLIPGAIAYYPPGLQKGFEHFIYFICALFSCLMLVESLMMIV-----ASIV 513
IP L+ S + I Y G++ + F IC + SL + + A V
Sbjct: 469 ELIPRRLLPSTVFSLITYVIAGVKMSMKCFFTMICTIMVLAYSASSLPLSIGAGENAVAV 528
Query: 514 PDFLMGI--ITGAGIQGIMMLAGGFFRLPNDLPNPFWRYPMFYISFHRYAFQGSYKNEFE 571
P L+ I + G+ + G F LP W + Y S Y F+ NEF
Sbjct: 529 PTLLVTIYFVFMLFFSGLSLYPGSF------LPKLSW---IQYFSIPHYGFRALLHNEFL 579
Query: 572 GLKF----ERDEIGGSLNYI--SGEEILRNKFHVDMSYSKWVD-LGVLLGMIVLYRVVFL 624
G F +E+ NY+ +GEE L + S+ W + L ++ MI+L + ++
Sbjct: 580 GQNFCPEHNTEEVSRCHNYVICTGEEFLMIQGIDLSSWGFWENHLALVCTMIILLTITYV 639
Query: 625 IIIK 628
+++
Sbjct: 640 QLLQ 643
>ABG5_RAT (Q99PE7) ATP-binding cassette, sub-family G, member 5
(Sterolin-1)
Length = 652
Score = 195 bits (496), Expect = 3e-49
Identities = 149/543 (27%), Positives = 269/543 (49%), Gaps = 38/543 (6%)
Query: 48 KSILQGLTGYAKPAQLLAIMGPSGCGKSTLLDALAGRLGSNTRQSGDILINGN--KQALA 105
+ IL+ ++ Y + Q + I+G SG GK+TLLDA++GRL G++ +NG ++
Sbjct: 67 RKILKDVSLYIESGQTMCILGSSGSGKTTLLDAISGRLRRTGTLEGEVFVNGCELRRDQF 126
Query: 106 YGTSAYVTQDDTLLTTLTVKEAVYYSAQLQLPDTMSNEEKKERADFTIREMGLQDAINTR 165
+Y+ Q D L++LTV+E + Y+A L L + ++ K + + + E+ L +
Sbjct: 127 QDCVSYLLQSDVFLSSLTVRETLRYTAMLALRSSSADFYDK-KVEAVLTELSLSHVADQM 185
Query: 166 IGGWGVKGISGGQKRRVSISIEILTRPRLLFLDEPTSGLDSAASYYVMKRIASLDKKDGI 225
IG + GIS G++RRVSI+ ++L P+++ LDEPT+GLD + +++ + L +++
Sbjct: 186 IGNYNFGGISSGERRRVSIAAQLLQDPKVMMLDEPTTGLDCMTANHIVLLLVELARRN-- 243
Query: 226 QRTIVASIHQPSTEVFQLFHNLCLLSSGKTVYFGPASAASEFFASNGFPCPPLQNPSDHL 285
R ++ +IHQP +E+F F + +L+ G+ V+ G FF + G+PCP NP D
Sbjct: 244 -RIVIVTIHQPRSELFHHFDKIAILTYGELVFCGTPEEMLGFFNNCGYPCPEHSNPFDFY 302
Query: 286 LKTINKDFDQDIEMDLSETGTISIEQAIDILVSSYSSSERNQEIKNEVSVLSIVLSLKDN 345
+ + D S I + + +L S++ S+ +I + + +L
Sbjct: 303 MDLTSVDTQ-------SREREIETYKRVQMLESAFRQSDICHKILENIERTRHLKTLP-- 353
Query: 346 NSTYKKKH-AGFLNQCLVLTRRSFVNMFRDLGYYWLRL------GIYIALAISLATVFND 398
+K K+ G + VL RR N+ R+ +RL G++ L L V N+
Sbjct: 354 MVPFKTKNPPGMFCKLGVLLRRVTRNLMRNKQVVIMRLVQNLIMGLF--LIFYLLRVQNN 411
Query: 399 LDKSNGSIQDRGSLLMFVFSFLTFM----TIGGFPSYVEDMKVFERERLNGHYGVTAYVI 454
+ K G++QDR LL + + + FP V ++E +G Y ++
Sbjct: 412 MLK--GAVQDRVGLLYQLVGATPYTGMLNAVNLFPML---RAVSDQESQDGLYQKWQMLL 466
Query: 455 GNTLSAIPYLLMISLIPGAIAYYPPGLQKGFEHFIYFICALFSCLMLVESLMMIVASIV- 513
L A+P+ ++ ++I ++ Y+ GL F YF AL + ++ E L +++ +V
Sbjct: 467 AYVLHALPFSIVATVIFSSVCYWTLGLYPEVARFGYFSAALLAPHLIGEFLTLVLLGMVQ 526
Query: 514 -PDFLMGIITGAGIQGIMMLAGGFFRLPNDLPNPFWRYPMFYISFHRYAFQGSYKNEFEG 572
P+ + I+ I G +++ GF R ++P P + Y +F +Y + NEF G
Sbjct: 527 NPNIVNSIVALLSISG-LLIGSGFIRNIEEMPIPL--KILGYFTFQKYCCEILVVNEFYG 583
Query: 573 LKF 575
L F
Sbjct: 584 LNF 586
>CDR3_CANAL (O42690) Opaque-specific ABC transporter CDR3
Length = 1501
Score = 186 bits (472), Expect = 2e-46
Identities = 151/502 (30%), Positives = 248/502 (49%), Gaps = 43/502 (8%)
Query: 30 WKDLWVTVSASTGKTNESKSILQGLTGYAKPAQLLAIMGPSGCGKSTLLDALAGRLGSNT 89
W++L TV + E + IL + G+ KP ++ A+MG SG GK+TLL+AL+ RL +
Sbjct: 842 WRNLTYTVKIKS----EERVILNNIDGWVKPGEVTALMGASGAGKTTLLNALSERLTTGV 897
Query: 90 RQSGDILINGNKQALAYGTS-AYVTQDDTLLTTLTVKEAVYYSAQLQLPDTMSNEEKKER 148
SG ++NG + ++ S YV Q D L T TV+EA+ +SA+L+ P+++S EK
Sbjct: 898 ITSGTRMVNGGELDSSFQRSIGYVQQQDLHLETSTVREALKFSARLRQPNSVSIAEKDSY 957
Query: 149 ADFTIREMGLQDAINTRIGGWGVKGISGGQKRRVSISIEILTRPRLL-FLDEPTSGLDSA 207
+ I + ++ ++ +G G +G++ Q++R++I++E++ RP+LL FLDEPTSGLDS
Sbjct: 958 VEKIIDLLEMRTYVDAIVGVPG-EGLNVEQRKRLTIAVELVARPKLLVFLDEPTSGLDSQ 1016
Query: 208 ASYYVMKRIASLDKKDGIQRTIVASIHQPSTEVFQLFHNLCLLSSGKTVYFGPASA---- 263
++ + K I L + I+ +IHQPS + + F L LL G+TVYFG A
Sbjct: 1017 TAWSICKLIRKLANHG---QAILCTIHQPSAILLEEFDRLLLLQKGETVYFGEFGANCHT 1073
Query: 264 ASEFFASNG-FPCPPLQNPSDHLLKTINKDFDQDIEMDLSETGTISIEQAIDILVSSYSS 322
E+F NG CP NP++ +L I D ET S E Y +
Sbjct: 1074 LIEYFERNGASKCPQHANPAEWMLGVIGAAPGTQANQDYFETWRNSPE---------YRA 1124
Query: 323 SERNQEIKNEVSVLSIVLSLKDNNSTYKKKHAGFLNQCLVLTRRSFVNMFRDLGYYWLRL 382
+ E+ L+ D N Y A F Q + + R F +R Y + +
Sbjct: 1125 VQNELHRLEEMPGLASGEKEPDTNQAYA---ASFWKQYIFVVHRLFQQYWRTPSYIYSKF 1181
Query: 383 GIYIALAISLATVFNDLD--KSNGSIQDRGSLLMFVFSF---LTFMTIGGFPSYVEDMKV 437
+ + L ++FN KS S+Q + ++ +FS LT + P +V +
Sbjct: 1182 AMAV-----LCSLFNGFTYYKSQNSMQGLKNQMLSIFSMFVVLTTLAQQYVPLFVTQRDL 1236
Query: 438 FE-RERLNGHYGVTAYVIGNTLSAIPYLLMISLIPGAIAYYPPGLQKGFEHFIY--FICA 494
+E RER + + A++ + IPY ++ + I YYP GL + + +Y +
Sbjct: 1237 YEARERPSKTFSWLAFIAAQITAEIPYQVLAATISFFSWYYPVGL---YRNAVYSGAVTH 1293
Query: 495 LFSCLMLVESLMMIVASIVPDF 516
+ L+ +LM I +S + F
Sbjct: 1294 RGVLMWLIMTLMFIYSSTLAQF 1315
Score = 126 bits (316), Expect = 2e-28
Identities = 145/660 (21%), Positives = 270/660 (39%), Gaps = 60/660 (9%)
Query: 47 SKSILQGLTGYAKPAQLLAIMGPSGCGKSTLLDALAGRL-GSNTRQSGDILINGNKQALA 105
S IL+ + G KP ++ ++G G G ST L +A R G + I +G Q
Sbjct: 157 SFDILKPMEGLIKPGEVTVVLGRPGAGCSTFLKTIACRTEGFHVADGSVISYDGITQDEI 216
Query: 106 Y----GTSAYVTQDDTLLTTLTVKEAVYYSAQLQLPDT----MSNEE-KKERADFTIREM 156
G Y + +T LTV E + ++A ++ P +S EE K D +
Sbjct: 217 RNHLRGEVVYCAETETHFPNLTVGETLEFAALMKTPQNRPMGVSREEYAKHVVDVVMATY 276
Query: 157 GLQDAINTRIGGWGVKGISGGQKRRVSISIEILTRPRLLFLDEPTSGLDSAASYYVMKRI 216
GL NT++G ++GISGG+++R+SI+ L + + D T GLD+A + ++ I
Sbjct: 277 GLSHTKNTKVGNDFIRGISGGERKRLSIAEVTLVQASIQCWDNSTRGLDAATA---LEFI 333
Query: 217 ASLDKKDGIQR-TIVASIHQPSTEVFQLFHNLCLLSSGKTVYFGPASAASEFFASNGFPC 275
+SL I T + +I+Q S + LF + ++ G ++FG + A+ +F GF C
Sbjct: 334 SSLKTSASILNDTPLIAIYQCSQNAYDLFDKVIVMYEGYQIFFGSSQRAAAYFKKMGFVC 393
Query: 276 PPLQNPSDHLL-------KTINKDFDQDIEMDLSETGTI----SIEQAIDILVSSYSSSE 324
Q D L + I +++ + E QA+ + Y +
Sbjct: 394 QDRQTTPDFLTSITSPAERIIKPGYERLVPRTPKEFYRYWRRSPERQALLEEIDEYLDNC 453
Query: 325 RNQEIKNEVSVLSIVLSLKDNNSTYKKKH--AGFLNQCLVLTRRSFVNMFRDLGYYWLRL 382
N + K ++ + + K TY K Q + +R + M D+ +
Sbjct: 454 ENYDQKQKIFEAN---NAKKAKHTYNKSSYTVSLPMQVRYIMKRYWDRMRGDIIVPLSTV 510
Query: 383 GIYIALAISLATVFNDLDKSNGSIQDRGSLLMFVFSFLTFMTIGGFPSYVEDMKVFERER 442
IA+A+ L++VF +L ++ S R S++ + F + ++ + E + ++ R
Sbjct: 511 AGNIAMALILSSVFYNLQPNSSSFYYRTSVMYYALLFNAYSSVLEIYNMYEGRAIVQKHR 570
Query: 443 LNGHYGVTAYVIGNTLSAIPYLLMISLIPGAIAYYPPGLQKGFEHFIYFICALFSCLMLV 502
Y A IG+ +S P ++ S++ I Y+ ++ F +++ F + +
Sbjct: 571 EYALYPPMADAIGSIISDFPLKVVCSVLFNLILYFMVNFKREPGAFFFYLLISFCSTLFM 630
Query: 503 ESLMMIVASIVPDFLMGIITGAGIQGIMMLAGGFFRLPNDLPNPF---WRYPMFYISFHR 559
L + + + + + + GF +P + W + +++
Sbjct: 631 SHLFRTIGAFTNSLAEAMTPSSLLLFALSTFSGFA-----IPVTYMLGWCKWIRWVNPLA 685
Query: 560 YAFQGSYKNEFEGLKFE---------------RDEIGGSLNYISGE----EILRNKFHVD 600
YA++ NEF G F+ + S+ + GE L K D
Sbjct: 686 YAYEALISNEFHGRVFDCSNIVPSGFGYPKTGNSVVCASIGALPGEFKVDGDLYLKLAFD 745
Query: 601 MSYSK-WVDLGVLLGMIVLY--RVVFLIIIKTTEKLKPIVMSFMSVSPRQTRQILENPTA 657
SYS W + GVL+ I+ +F + + K + F + R+ R++ E+ A
Sbjct: 746 YSYSNVWRNFGVLMAFIIFLFGTTIFFVQTNKSSISKGETLVFRRKNIRKMRKMEEDEEA 805
>YQ5C_CAEEL (Q09466) Putative ABC transporter C16C10.12 in
chromosome III
Length = 610
Score = 186 bits (471), Expect = 2e-46
Identities = 143/543 (26%), Positives = 258/543 (47%), Gaps = 32/543 (5%)
Query: 34 WVTVSASTGK---TNESKSILQGLTGYAKPAQLLAIMGPSGCGKSTLLDALAGRLGSNTR 90
W + T K + + K +L ++G AKP +++A+MG SG GK+TL++ L R
Sbjct: 37 WENIEVKTRKKLFSKKQKQLLNRVSGIAKPGEMVALMGASGAGKTTLMNVLMCRNMKGLE 96
Query: 91 QSGDILINGNKQALAYGT-SAYVTQDDTLLTTLTVKEAVYYSAQLQLPDTMSNEEKKERA 149
++G + +NG K S + Q + + TLTV E + A+L++ + ++ER
Sbjct: 97 KNGTVKVNGTKIGKEISLISGFAQQQEIFIPTLTVDEYLMIQARLRMK--ANKHTRRERV 154
Query: 150 DFTIREMGLQDAINTRIGGWG-VKGISGGQKRRVSISIEILTRPRLLFLDEPTSGLDSAA 208
D I + LQ+ + +IG G VKGISGG+ RR++ + E+L+ P LLF DEPTSGLDS
Sbjct: 155 DEIIEMLRLQNCRDLKIGTPGLVKGISGGEARRLTFACELLSNPSLLFADEPTSGLDSFM 214
Query: 209 SYYVMKRIASLDKKDGIQRTIVASIHQPSTEVFQLFHNLCLLSSGKTVYFGPASAASEFF 268
+ V++ + +L RT+ IHQP+ E+F F + LS GKT + G + +FF
Sbjct: 215 AASVVQILKNLANSG---RTL---IHQPTAELFFQFDKIIFLSMGKTAFMGTPHESVKFF 268
Query: 269 ASNGFPCPPLQNPSDHLLKTINKDFDQDIEMDLSETGTISIEQAIDILVSSYSSSERNQE 328
A G P P L NP + + ++ + + I ++ Y S +Q+
Sbjct: 269 ADCGHPIPKLFNPPEWI----------QSKLSVIPNNETKSRETIGKIIEFYEKSIIHQK 318
Query: 329 IKNEVSVLSIVLSLKDNNSTYKKKHAGFLNQCLVLTRRSFVNMFRDLGYYWLRLGIYIAL 388
E+ V++ ++ GF + L +R+ +++ R ++L + +
Sbjct: 319 SIVEIRVIA------TTELPPYIENPGFFAETGALLKRACLDVIRSPAQMRMKLIQKVVM 372
Query: 389 AISLATVFNDLDKSNGSIQDRGSLLMFVFSFLTFMTIGGFPSYVE-DMKVFERERLNGHY 447
+ + +++ +++ S L F+ + LTF T+ G +++E ++ + RE +G +
Sbjct: 373 GLFIGSLYWQQPLDPRGVRNTNSALYFLIAELTFSTMFGIMTFMEHELPLIAREYHDGLF 432
Query: 448 GVTAYVIGNTLSAIPYLLMISLIPGAIAYYPPGLQKGFEHFIYFICALFSCLMLVESLMM 507
V +Y I LS +P + + I+Y+ GL ++ I S +
Sbjct: 433 YVISYYISRFLSYLPLFTIDGALMIVISYWMIGLNSTWQQVAKSILISVLVEQSATSCGL 492
Query: 508 IVASIVPDFLMGIITGAGIQGIMMLAGGFFRLPNDLPNPFWRYPMFYISFHRYAFQGSYK 567
+A + + I G+ L G + N+ P + R+ M + S+ RY F+G
Sbjct: 493 FLACLFETTSLAIAFAVPASGLFALLSGLYGNTNNFP-VYIRW-MQWTSWCRYGFEGLVV 550
Query: 568 NEF 570
N++
Sbjct: 551 NQW 553
>CDR4_CANAL (O74676) ABC transporter CDR4
Length = 1490
Score = 185 bits (469), Expect = 4e-46
Identities = 145/490 (29%), Positives = 243/490 (49%), Gaps = 48/490 (9%)
Query: 30 WKDLWVTVSASTGKTNESKSILQGLTGYAKPAQLLAIMGPSGCGKSTLLDALAGRLGSNT 89
W+DL V + E + IL ++G+ KP Q+ A+MG SG GK+TLL+AL+ RL +
Sbjct: 848 WRDLTYQVKIKS----EDRVILDHVSGWVKPGQVTALMGASGAGKTTLLNALSDRLTTGV 903
Query: 90 RQSGDILINGNKQALAYGTS-AYVTQDDTLLTTLTVKEAVYYSAQLQLPDTMSNEEKKER 148
G L+NG ++ S YV Q D L T TV+EA+ ++A L+ P ++S +EK E
Sbjct: 904 VTEGIRLVNGRPLDSSFQRSIGYVQQQDLHLETSTVREALEFAAYLRQPKSVSRKEKNEY 963
Query: 149 ADFTIREMGLQDAINTRIGGWGVKGISGGQKRRVSISIEILTRPRLL-FLDEPTSGLDSA 207
D+ IR + ++ + +G G +G++ Q++R+SI +E++ +P+LL FLDEPTSGLDS
Sbjct: 964 VDYIIRLLEMEQYADAVVGVSG-EGLNVEQRKRLSIGVELVAKPKLLVFLDEPTSGLDSQ 1022
Query: 208 ASYYVMKRIASLDKKDGIQRTIVASIHQPSTEVFQLFHNLCLLS-SGKTVYFGPA----S 262
++ + K I L + I+ +IHQPS + F L L G+TVYFG +
Sbjct: 1023 TAWSICKLIRKLADNG---QAILCTIHQPSAILLAEFDRLLFLQRGGQTVYFGDLGKNFT 1079
Query: 263 AASEFFASNGFP-CPPLQNPSDHLLKTINKDFDQDIEMDLSETGTISIEQAIDILVSSYS 321
+F G P CPP NP++ +L+ I + G+ + + D+ + S
Sbjct: 1080 TLINYFEKYGAPKCPPEANPAEWMLEVIG-----------AAPGSKANQDYYDVWLKSSE 1128
Query: 322 SSERNQEIKNEVSVLSIVLSLKDNNSTYKKKHAGFLNQCLVLTRRSFVNMFRDLGYYWLR 381
E N E+ + +S + L D+ K A + Q L +T+R F +R Y + +
Sbjct: 1129 FQEMNSEL-DLMSEELVKKPLDDDPDRLKPYAAPYWEQYLFVTKRVFEQNWRTPSYLYSK 1187
Query: 382 LGIYIALAISLATVFNDLD--KSNGSIQDRGSLLMFVFSFLTFMTI---GGFPSYVEDMK 436
L + +++FN K++ S+Q + + VF FL + P++V
Sbjct: 1188 F-----LLVVTSSLFNGFSFYKADRSLQGLQNQMFSVFMFLVILHTLIQQYLPTFVSQRD 1242
Query: 437 VFE-RERLNGHYGVTAYVIGNTLSAIPYLLMISLIPGAIAYYPPGLQKGFEH-------- 487
++E RER + + ++ + IP+ ++ + YYP GL + +
Sbjct: 1243 LYEVRERPSKTFSWITFIAAQVTAEIPWNIICGTLGYFCWYYPVGLYQNATYTNTVHQRG 1302
Query: 488 -FIYFICALF 496
F++F LF
Sbjct: 1303 AFMWFAIVLF 1312
Score = 137 bits (346), Expect = 7e-32
Identities = 132/629 (20%), Positives = 259/629 (40%), Gaps = 56/629 (8%)
Query: 44 TNESKSILQGLTGYAKPAQLLAIMGPSGCGKSTLLDALAGRL-GSNTRQSGDILING--- 99
T + IL+ + G KP +L ++G G G ST L +A + G + + I N
Sbjct: 166 TGPTFDILKPMDGLIKPGELTVVLGRPGAGCSTFLKTIASQTYGYHIDKDSVIRYNSLTP 225
Query: 100 -NKQALAYGTSAYVTQDDTLLTTLTVKEAVYYSAQLQLPDTMS-----NEEKKERADFTI 153
+ G Y + + LTV + + ++A+++ P + + A +
Sbjct: 226 HEIKKHYRGEVVYCAETENHFPQLTVGDTLEFAAKMRTPQNRPLGVSRDAYARHLAAVVM 285
Query: 154 REMGLQDAINTRIGGWGVKGISGGQKRRVSISIEILTRPRLLFLDEPTSGLDSAASYYVM 213
GL NT++G ++G+SGG+++RVSI+ L + D T GLDSA + +
Sbjct: 286 AVYGLSHTRNTKVGNDFIRGVSGGERKRVSIAEITLNNAMVQCWDNSTRGLDSATALEFI 345
Query: 214 KRIASLDKKDGIQRTIVASIHQPSTEVFQLFHNLCLLSSGKTVYFGPASAASEFFASNGF 273
+ + + D + T + +I+Q S + + LF + L+ G +YFG A A ++F G+
Sbjct: 346 RALKA--SADIVHTTPLVAIYQCSQDAYDLFDKVVLMYQGYQIYFGSAKKAKQYFIDMGY 403
Query: 274 PCPPLQNPSDHLLKTIN---KDFDQDIEMDLSETGT------------ISIEQAIDILVS 318
CP Q +D L N + Q E + +T I +D ++
Sbjct: 404 ECPQRQTTADFLTSLTNPAERIVRQGFEGKVPQTPQEFYEYWKKSPEGQQIVADVDQYLT 463
Query: 319 SYSSSERNQEIKNEVSVLSIVLSLKDNNSTYKKKHAGFLNQCLVLTRRSFVNMFRDLGYY 378
+SS+ + IK D+ F Q + R+ + + + +
Sbjct: 464 EHSSAAEKEAIKEAHQARQ-----SDHLKPASPYTVSFFMQVRYIAHRNILRIKGNPSIH 518
Query: 379 WLRLGIYIALAISLATVFNDLDKSNGSIQDRGSLLMFVFSFLTFMTIGGFPSYVEDMKVF 438
++ I ++ L+++F +L + S R + L F F F + S E +
Sbjct: 519 LFQIFGNIGMSFILSSIFYNLPTATSSFYHRTAALFFAVLFNAFSCLLEIFSLYEARSIV 578
Query: 439 ERERLNGHYGVTAYVIGNTLSAIPYLLMISLIPGAIAYYPPGLQKGFEHFIYFICALFSC 498
E+ + Y A + ++ +P +I++ + Y+ ++ +F +++ FS
Sbjct: 579 EKHKKYALYHPAADAFASIVTELPTKFIIAIGFNLVYYFMVNFRRTPGNFFFYLLINFSA 638
Query: 499 LMLVESLMMIVASIVPDFLMGIITGAGIQGIMMLAGGFFRLPNDLPNPF-WRYPMFYISF 557
+ + + + + L +T A I + + F +P PN W + Y+
Sbjct: 639 TLAMSHIFRTIGAATKT-LQEAMTPAAILLLALTIFTGFVIPT--PNMHGWCRWINYLDP 695
Query: 558 HRYAFQGSYKNEFEGLKFERDEI---GGS------------LNYISGEEILRNKFHVDMS 602
YAF+ NEF FE + GGS + + G++ + +++MS
Sbjct: 696 LAYAFESLIANEFHNRDFECSQYVPSGGSYPTAGPNRICTPVGSVPGQDFVDGTRYMEMS 755
Query: 603 YS-----KWVDLGVLLGMIVLYRVVFLII 626
+ KW + G+++G IV + ++++
Sbjct: 756 FDYRNSHKWRNFGIVIGFIVFFFCTYILL 784
Database: sprot
Posted date: Nov 25, 2004 10:54 AM
Number of letters in database: 59,974,054
Number of sequences in database: 164,201
Lambda K H
0.321 0.138 0.399
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 75,890,530
Number of Sequences: 164201
Number of extensions: 3194924
Number of successful extensions: 13442
Number of sequences better than 10.0: 945
Number of HSP's better than 10.0 without gapping: 851
Number of HSP's successfully gapped in prelim test: 94
Number of HSP's that attempted gapping in prelim test: 11258
Number of HSP's gapped (non-prelim): 1305
length of query: 665
length of database: 59,974,054
effective HSP length: 117
effective length of query: 548
effective length of database: 40,762,537
effective search space: 22337870276
effective search space used: 22337870276
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 69 (31.2 bits)
Medicago: description of AC121245.8