BLAST2 result
BLASTP 2.2.2 [Dec-14-2001]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= AC119414.1 + phase: 0
(489 letters)
Database: sprot
164,201 sequences; 59,974,054 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
TT12_ARATH (Q9LYT3) TRANSPARENT TESTA 12 protein 343 8e-94
YAO6_SCHPO (Q10085) Hypothetical protein C11D3.06 in chromosome I 147 6e-35
YD38_YEAST (Q05497) Hypothetical 77.8 kDa protein in MRPS28-HXT7... 145 2e-34
NORM_VIBCH (Q9KRU4) Probable multidrug resistance protein norM (... 98 4e-20
NORM_VIBVU (Q8D9N8) Probable multidrug resistance protein norM (... 96 2e-19
NORM_HAEIN (P45272) Probable multidrug resistance protein norM (... 94 6e-19
NORM_PASMU (Q9CMZ9) Probable multidrug resistance protein norM (... 93 2e-18
YHJ2_YEAST (P38767) Hypothetical 64.2 kDa protein in SLT2-PUT2 i... 87 1e-16
NORM_BACSU (O31855) Probable multidrug resistance protein norM (... 87 1e-16
NORM_VIBPA (O82855) Multidrug resistance protein norM (Na(+)/dru... 82 2e-15
NORM_DEIRA (Q9RY44) Probable multidrug resistance protein norM (... 80 9e-15
NOM1_PSEAE (Q9I3Y3) Probable multidrug resistance protein norM 1... 79 3e-14
NORM_NEIMA (Q9JV27) Probable multidrug resistance protein norM (... 76 2e-13
NORM_NEIMB (Q9K015) Probable multidrug resistance protein norM (... 75 4e-13
NORM_BACHD (Q9KEJ2) Probable multidrug resistance protein norM (... 72 4e-12
NORM_ECOLI (P37340) Multidrug resistance protein norM (Na(+)/dru... 71 7e-12
NORM_ECOL6 (Q8FH68) Multidrug resistance protein norM (Na(+)/dru... 71 7e-12
NORM_ECO57 (P58164) Multidrug resistance protein norM (Na(+)/dru... 71 7e-12
NORM_XYLFT (Q879Z5) Probable multidrug resistance protein norM (... 70 1e-11
NORM_XYLFA (Q9PA34) Probable multidrug resistance protein norM (... 68 5e-11
>TT12_ARATH (Q9LYT3) TRANSPARENT TESTA 12 protein
Length = 507
Score = 343 bits (879), Expect = 8e-94
Identities = 185/480 (38%), Positives = 286/480 (59%), Gaps = 8/480 (1%)
Query: 1 MSKVEASEALVEAKVPLLKNNIDEHENEVLGR-----RVWNESKKLWHIAGPAIFNRVSN 55
++++ + + E P ++ + + V R VW ESK LW ++G +I V N
Sbjct: 11 LTRLHSDSQITERSSPEIEEFLRRRGSTVTPRWWLKLAVW-ESKLLWTLSGASIVVSVLN 69
Query: 56 YSMLVITQVFAGHLGDMELAATSIAMNLILGLDLGIMLGMSSALETLCGQAFGAKQFNML 115
Y + +T +F GHLG ++LA SIA I GL GIMLGM+SA++T+CGQA+GA+Q++ +
Sbjct: 70 YMLSFVTVMFTGHLGSLQLAGASIATVGIQGLAYGIMLGMASAVQTVCGQAYGARQYSSM 129
Query: 116 GIYMQRSWIVLFITGILLLPLFIFATPILNFFGQPQEISELAGVISMWLIPTHVTYAFFF 175
GI QR+ ++ + L L+ ++ PIL GQ I+ + + +IP +A
Sbjct: 130 GIICQRAMVLHLAAAVFLTFLYWYSGPILKTMGQSVAIAHEGQIFARGMIPQIYAFALAC 189
Query: 176 PLYFFLQSQLKNNIIGWVSLVALLVHVFLCWLVVVKFKLGVIALVASGNVAWIVLVFGFF 235
P+ FLQ+Q N + ++SL L+H L WLV G++ + +W +LV
Sbjct: 190 PMQRFLQAQNIVNPLAYMSLGVFLLHTLLTWLVTNVLDFGLLGAALILSFSWWLLVAVNG 249
Query: 236 GYAVLC-GCPLTWTGFSMEAFFDLWEFAKLSAASGVMLCLEVWYDKVLMLMTGNLHNAKK 294
Y ++ C TWTGFS AF +W + KL+ AS VMLCLE+WY++ L++++G L N
Sbjct: 250 MYILMSPNCKETWTGFSTRAFRGIWPYFKLTVASAVMLCLEIWYNQGLVIISGLLSNPTI 309
Query: 295 FVEALTICLTLNIWELMFPLGFLAATGVRVANELGAGNGQAAKFASAVAVVTSIIISVFF 354
++A++IC+ W++ F LG AA VRV+NELGAGN + A + V +T+++IS
Sbjct: 310 SLDAISICMYYLNWDMQFMLGLSAAISVRVSNELGAGNPRVAMLSVVVVNITTVLISSVL 369
Query: 355 WLLIMIFRRQIGYLFTSSELVIEEVNKLSPLLGFTILLNSVQPVLSGVAIGSGWQKYVAY 414
+++++FR + FTS VI V+ L PLL +I LN +QP+LSGVAIGSGWQ VAY
Sbjct: 370 CVIVLVFRVGLSKAFTSDAEVIAAVSDLFPLLAVSIFLNGIQPILSGVAIGSGWQAVVAY 429
Query: 415 IDLGCYYLIGMPLGFLMGFVFQFGVEGLWAGLVCGGPAIQTLILAWVTIRCDWNKEAERA 474
++L YY+IG+P+G ++GF GV G+W G++ G +QTL L +T++ +W E E A
Sbjct: 430 VNLVTYYVIGLPIGCVLGFKTSLGVAGIWWGMI-AGVILQTLTLIVLTLKTNWTSEVENA 488
>YAO6_SCHPO (Q10085) Hypothetical protein C11D3.06 in chromosome I
Length = 455
Score = 147 bits (371), Expect = 6e-35
Identities = 124/451 (27%), Positives = 208/451 (45%), Gaps = 9/451 (1%)
Query: 33 RVWNESKKLWHIAGPAIFNRVSNYSMLVITQVFAGHLGDMELAATSIAMNLILGLDLGIM 92
R E K L + P I S+ + + G LG EL+ + A + I
Sbjct: 3 RPLTEVKYLLINSAPVILGYALQNSLQTSSVIVTGRLGPSELSVAAFAYMFAMSTGWLIA 62
Query: 93 LGMSSALETLCGQAFGAKQFNMLGIYMQRSWIVLFITGILLLPLFIFATPILNFFGQPQE 152
LG ++A +TL +GA + LGI +Q +IVL I + + ++ ++ PIL F Q E
Sbjct: 63 LGGTTAFDTLGSNLWGAGKKQELGILLQTGFIVLSILYLPICLVWWYSKPILIFLHQTPE 122
Query: 153 ISELAGVISMWLIPTHVTYAFFFPLYFFLQSQLKNNIIGWVSLVALLVHVFLCWLVVVKF 212
++E + +LIP + Y F L FLQ+Q ++ LV ++V L +L+V +
Sbjct: 123 LAEASQKFLRYLIPGGLGYVCFELLKKFLQTQEITRAGSYILLVTSPLNVALNFLLVHYY 182
Query: 213 KLGVI-ALVASGNVAWIVLVFGFFGYAVLCGCPLTWTGFSMEAFFDLWEFAKLSAASGVM 271
LG+ A +A+G W+ + YA W G++ + F KLS VM
Sbjct: 183 GLGLKGAPLATGLSYWLSFIL-LTQYAKYVKGAEAWNGWNKRCLENFGPFVKLSLLGIVM 241
Query: 272 LCLEVWYDKVLMLMTGNLHNAKKFVEALTICLTLNIWELMFPLGFLAATGVRVANELGAG 331
+ E W +++ L+ G L + A ++ +T + P G T RVA LGAG
Sbjct: 242 VGTEWWAFEIVALVAGKLGAVP--LAAQSVIMTTDQLLNTIPFGLGIITSNRVAYYLGAG 299
Query: 332 NGQAAKFASAVAVVTSIIISVFFWLLIMIFRRQIGYLFTSSELVIEEVNKLSPLLGFTIL 391
A + VA + + + + ++ R G +FT+ VI+ V + PL+ +
Sbjct: 300 LPDNASLTAKVAAIVGVAVGSVIMITMIAVRNIYGRIFTNDPDVIQLVALVMPLVAAFQI 359
Query: 392 LNSVQPVLSGVAIGSGWQKYVAYIDLGCYYLIGMPLGFLMGFVFQFGVEGLWAGLVCGGP 451
+S+ + G G+G QK A +++ YYL +PLG + F + G+ GLW G V
Sbjct: 360 SDSLNGTMGGALRGTGRQKVGAIVNITAYYLFALPLGIYLAFHGK-GLVGLWIGQVIALS 418
Query: 452 AIQTLILAWVTIRCDWNKEAERAKLHLSKWG 482
+ L L + + DW ++ +A +S++G
Sbjct: 419 IVGILELK-IVMATDWISQSRKA---ISRFG 445
>YD38_YEAST (Q05497) Hypothetical 77.8 kDa protein in MRPS28-HXT7
intergenic region
Length = 695
Score = 145 bits (366), Expect = 2e-34
Identities = 119/467 (25%), Positives = 219/467 (46%), Gaps = 20/467 (4%)
Query: 15 VPLLKNNIDEHENEVLGRRVWN------ESKKLWHIAGPAIFNRVSNYSMLVITQVFAGH 68
VP + IDE+++E L + E++ L + P IF + ++ + GH
Sbjct: 200 VPTIYQEIDENDSEALAELAHSHVTFKSEARVLASYSFPLIFTFLLEQIFPMVCSLTVGH 259
Query: 69 LGDMELAATSIAMNLILGLDLGIMLGMSSALETLCGQAFGAKQFNMLGIYMQRSWIVLFI 128
LG ELAA S+A ++ + L I G++++L+TLC QA+G+ +F +G+++QR +
Sbjct: 260 LGKNELAAVSLA-SMTSNITLAIFEGIATSLDTLCPQAYGSGRFYSVGVHLQRCIAFSLV 318
Query: 129 TGILLLPLFIFATPILNFFGQPQEISELAGVISMWLIPTHVTYAFFFPLYFFLQSQLKNN 188
I ++ ++ P+L++ +E+ L LI Y FF L FLQ+Q +
Sbjct: 319 IYIPFAVMWWYSEPLLSYIIPEKELINLTSRFLRVLILGAPAYIFFENLKRFLQAQGIFD 378
Query: 189 IIGWVSLVALLVHVFLCWLVVVKFKLGV------IALVASGNVAWIVLVFGFFGYAVLCG 242
+V + ++V + + +V +GV IA+V + + + +L+F YA+
Sbjct: 379 AGIYVLTICAPLNVLVSYTLVWNKYIGVGFIGAAIAVVLNFWLMFFLLLF----YALYID 434
Query: 243 CPLTWTGFSMEAFFDLWEFAKLSAASGVMLCLEVWYDKVLMLMTGNLHNAKKFVEALTIC 302
W GFS +AF + L+ + +ML E ++L L + + ++ A +
Sbjct: 435 GRKCWGGFSRKAFTHWNDLGHLAFSGIIMLEAEELSYELLTLFSA--YYGVSYLAAQSAV 492
Query: 303 LTLNIWELMFPLGFLAATGVRVANELGAGNGQAAKFASAVAVVTSIIISVFFWLLIMIFR 362
T+ M P +T R+AN +GA A +S V + S I +++ R
Sbjct: 493 STMAALLYMIPFAIGISTSTRIANFIGAKRTDFAHISSQVGLSFSFIAGFINCCILVFGR 552
Query: 363 RQIGYLFTSSELVIEEVNKLSPLLGFTILLNSVQPVLSGVAIGSGWQKYVAYIDLGCYYL 422
I +++ VI+ + ++ PL+G +S+ V G G Q + ++L YYL
Sbjct: 553 NLIANIYSKDPEVIKLIAQVLPLVGIVQNFDSLNAVAGSCLRGQGMQSLGSIVNLMAYYL 612
Query: 423 IGMPLGFLMGFVFQFGVEGLWAGLVCGGPAIQTLILAWVTIRCDWNK 469
G+PL ++ + F + GLW G + + L+ A+ + DW+K
Sbjct: 613 FGIPLALILSWFFDMKLYGLWIG-IGSAMLLIGLVEAYYVLFPDWDK 658
>NORM_VIBCH (Q9KRU4) Probable multidrug resistance protein norM
(Na(+)/drug antiporter) (Multidrug-efflux transporter)
Length = 461
Score = 98.2 bits (243), Expect = 4e-20
Identities = 112/471 (23%), Positives = 201/471 (41%), Gaps = 30/471 (6%)
Query: 26 ENEVLGRRVWNESKKLWHIAGPAIFNRVSNYSMLVITQVFAGHLGDMELAATSIAMNLIL 85
EN V R E+ L +A P + V+ M + + AG + +++AA SIA ++ L
Sbjct: 2 ENSV--HRYKKEASNLIKLATPVLIASVAQTGMGFVDTIMAGGVSAIDMAAVSIAASIWL 59
Query: 86 GLDLGIMLGMSSALETLCGQAFGAKQFNMLGIYMQRSWIVLFITGILLLPLFIFATPILN 145
L +G+ AL + Q GA + + + + + I+ + + ++ + +F T +
Sbjct: 60 PSIL-FGVGLLMALVPVVAQLNGAGRQHKIPFEVHQGLILALLVSVPIIAV-LFQTQFII 117
Query: 146 FFGQPQEISELAGVISMWLIPTHV-TYAFFFPLYFFLQSQLKNNIIGWVSLVALLVHVFL 204
F +E V M + V Y F L F + + LL+++ L
Sbjct: 118 RFMDVEEAMATKTVGYMHAVIFAVPAYLLFQALRSFTDGMSLTKPAMVIGFIGLLLNIPL 177
Query: 205 CWLVVV-KFKL----GVIALVASGNVAWIVLVFGFFGYAVLC---GCPLTWTGFSMEAFF 256
W+ V KF GV VA+ V WI+L+ F Y V + F
Sbjct: 178 NWIFVYGKFGAPELGGVGCGVATAIVYWIMLLLLLF-YIVTSKRLAHVKVFETFHKPQPK 236
Query: 257 DLWEFAKLSAASGVMLCLEVWYDKVLMLMTGNLHNAKKFVEALTICLTLNIWELMFPLGF 316
+L +L L EV V+ L+ L + V A + L + MFP+
Sbjct: 237 ELIRLFRLGFPVAAALFFEVTLFAVVALLVAPLGST--VVAAHQVALNFSSLVFMFPMSI 294
Query: 317 LAATGVRVANELGAGNGQAAKFASAVAVVTSIIISVFFWLLIMIFRRQIGYLFTSSELVI 376
AA +RV ++LG + + A A+ V ++T + + LL ++FR QI L+T +++V+
Sbjct: 295 GAAVSIRVGHKLGEQDTKGAAIAANVGLMTGLATACITALLTVLFREQIALLYTENQVVV 354
Query: 377 EEVNKLSPLLGFTILLNSVQPVLSGVAIGSGWQKYVAYIDLGCYYLIGMPLGFLMGFV-- 434
+L +++VQ V +G G + + Y+++G+P G+++G
Sbjct: 355 ALAMQLLLFAAIYQCMDAVQVVAAGSLRGYKDMTAIFHRTFISYWVLGLPTGYILGMTNW 414
Query: 435 ---FQFGVEGLWAGLVCGGPAIQTLI---LAWVTIRCDWNKEAERAKLHLS 479
G +G W G + G A ++ L W+ K+++ +LHL+
Sbjct: 415 LTEQPLGAKGFWLGFIIGLSAAALMLGQRLYWL------QKQSDDVQLHLA 459
>NORM_VIBVU (Q8D9N8) Probable multidrug resistance protein norM
(Na(+)/drug antiporter) (Multidrug-efflux transporter)
Length = 483
Score = 95.9 bits (237), Expect = 2e-19
Identities = 107/439 (24%), Positives = 182/439 (41%), Gaps = 36/439 (8%)
Query: 33 RVWNESKKLWHIAGPAIFNRVSNYSMLVITQVFAGHLGDMELAATSIAMNLILGLDLGIM 92
R E+ L +A P + V+ M + V AG + ++AA S+A ++ L L
Sbjct: 30 RYKKEASNLIKLATPVLIASVAQTGMGFVDTVMAGGVSATDMAAVSVAASIWLPSIL-FG 88
Query: 93 LGMSSALETLCGQAFGAKQFNMLGIYMQRSWIVLFITGILLLPLFIFATPILNFFGQPQE 152
+G+ AL + Q GA + + +Q+ ++ + I PI+ Q Q
Sbjct: 89 IGLLMALVPVVAQLNGAGKREQVPFEIQQGAVMALLISI----------PIIGVLFQTQW 138
Query: 153 ISELAGVISMWLIPT-HVTYAFFFPLYFFLQSQLKNNIIGWVSL---------VALLVHV 202
I V ++ T +A F + FL Q ++ +SL + LL+++
Sbjct: 139 ILGYMNVDAVMATKTIGYIHAVMFAVPAFLLFQTLRSLTDGLSLTKPAMVIGFIGLLLNI 198
Query: 203 FLCWLVVVKFKLGVIAL------VASGNVAWIVLVFGFFGYAVLCGCPLT--WTGFSMEA 254
L W+ V KLG AL VA+ V WI+ + F +T F
Sbjct: 199 PLNWMFVYG-KLGAPALGGVGCGVATAIVYWIMFLLLLFYVTTSHRLRQVQLFTTFHPPQ 257
Query: 255 FFDLWEFAKLSAASGVMLCLEVWYDKVLMLMTGNLHNAKKFVEALTICLTLNIWELMFPL 314
+ KL L EV V+ L+ L + V A + + + M P+
Sbjct: 258 LNAQVKLFKLGFPVAAALFFEVTLFAVVALLVAPLGST--VVAAHQVAINFSSLVFMLPM 315
Query: 315 GFLAATGVRVANELGAGNGQAAKFASAVAVVTSIIISVFFWLLIMIFRRQIGYLFTSSEL 374
AAT +RV + LG + + A+ AS V ++ + +VF LL +I R QI L+T + +
Sbjct: 316 SIGAATSIRVGHMLGEKSTEGARIASHVGILVGLSTAVFTALLTVILREQIALLYTDNRV 375
Query: 375 VIEEVNKLSPLLGFTILLNSVQPVLSGVAIGSGWQKYVAYIDLGCYYLIGMPLGFLMG-- 432
VI +L +++Q + +G G + + Y+L+G+P G+++G
Sbjct: 376 VITLAMQLLIFTAIYQCTDAIQVIAAGALRGYKDMRAIFNRTFIAYWLLGLPTGYVLGLT 435
Query: 433 --FVFQFGVEGLWAGLVCG 449
V G +G W G + G
Sbjct: 436 DWIVEPMGAQGFWIGFIVG 454
>NORM_HAEIN (P45272) Probable multidrug resistance protein norM
(Na(+)/drug antiporter) (Multidrug-efflux transporter)
Length = 464
Score = 94.4 bits (233), Expect = 6e-19
Identities = 102/434 (23%), Positives = 184/434 (41%), Gaps = 41/434 (9%)
Query: 39 KKLWHIAGPAIFNRVSNYSMLVITQVFAGHLGDMELAATSIAMNLILGLDL---GIMLGM 95
KKL I+ P + +++ SM + + AG + ++AA SI ++ + L G++L +
Sbjct: 14 KKLIKISLPILLAQIAQNSMGLADTIMAGRVSSTDMAAISIGASIWMPLMFFGQGLLLAL 73
Query: 96 SSALETLCGQAFGAKQFNMLGIYMQRSWIVLFITGILLLPLFIFATPILNFFGQPQEISE 155
+ L G + + Q W+VL ++ L L ++ P L + ++S+
Sbjct: 74 PPTISYLNGSG---QHHRIAHQVRQGIWLVLGVSIPLGLLIYFCEIP-LQYMQMESKMSD 129
Query: 156 LAGVI---SMWLIPTHVTYAFFFPLYFFLQSQLKNNIIGWVSLVALLVHVFLCWLVVV-K 211
LA +W +P ++ F L ++ +I + + LL+++ L ++ + K
Sbjct: 130 LARDYLHAMLWGLPAYLMLINFRCLNDGIEKTKPAMVI---TFLGLLINIPLNYIFIYGK 186
Query: 212 FKLGVIALVASGNVAWIV-----LVFGFFGYAVLCGCPLTWTGFSMEAFFDLWEFA---- 262
F + V G IV L+ F+ Y S++ F L E
Sbjct: 187 FGMPAFGAVGCGIATAIVNWAMCLMMIFYSYT-------NTQERSLKVFSQLIEMPNPKT 239
Query: 263 -----KLSAASGVMLCLEVWYDKVLMLMTGNLHNAKKFVEALTICLTLNIWELMFPLGFL 317
+L + +C EV + LM L V + I L + + MFP+
Sbjct: 240 LKKLLRLGLPIAIAICCEVALYALTSLMLSPL--GATIVASHQITLNTSSFIFMFPMSIG 297
Query: 318 AATGVRVANELGAGNGQAAKFASAVAVVTSIIISVFFWLLIMIFRRQIGYLFTSSELVIE 377
AT + V LGAG+ Q AK A++ + +++ L+ + FR +I +F + E+VI
Sbjct: 298 MATTILVGQALGAGSPQNAKKIGYAALLLGLTVTIVTALITIFFRYEIASIFVTDEIVIA 357
Query: 378 EVNKLSPLLGFTILLNSVQPVLSGVAIGSGWQKYVAYIDLGCYYLIGMPLGFLMG----F 433
L +++Q V+ G+ G K + YI L Y++IG+PLG+ +G
Sbjct: 358 MAANLLLFAALYQFSDTIQMVVGGILRGYKDTKVILYITLFSYWVIGVPLGYTLGRTDWL 417
Query: 434 VFQFGVEGLWAGLV 447
V +G W V
Sbjct: 418 VPHIDAKGFWIAFV 431
>NORM_PASMU (Q9CMZ9) Probable multidrug resistance protein norM
(Na(+)/drug antiporter) (Multidrug-efflux transporter)
Length = 464
Score = 92.8 bits (229), Expect = 2e-18
Identities = 99/439 (22%), Positives = 186/439 (41%), Gaps = 25/439 (5%)
Query: 37 ESKKLWHIAGPAIFNRVSNYSMLVITQVFAGHLGDMELAATSIAMNLILGLDL---GIML 93
E+KKL IA P + +++ SM ++ + +G + ++AA S+ ++ L L G++L
Sbjct: 12 EAKKLLLIALPILLAQIAQNSMGLVDTIMSGRVSSADMAAISVGASIWFPLVLFGHGLLL 71
Query: 94 GMSSALETLCGQAFGAKQFNMLGIYMQRSWIVLFITGILLLPLFIFATPILNFFGQPQEI 153
+ + L G K+ + Q WI+LF + + L L ++ + ++ +
Sbjct: 72 ALPPTISYLNGSG---KRDQIAHQVRQGIWIILF-SCLPLGILIYYSNLVFDYMQVEDHL 127
Query: 154 SELA-GVIS--MWLIPTHVTYAFFFPLYFFLQSQLKNNIIGWVSLVALLVHVFLCWLVVV 210
E+ G + +W +P ++ F L + +I + + L +++ L ++ +
Sbjct: 128 KEITIGYLHAMIWGLPAYLLMINFRCLNDGIAKTKPAMVI---TFLGLGLNIPLNYIFIY 184
Query: 211 KFKLGVIALVASGNVAWIVLVFGFFGYAVLCGCPLTWTGFSMEAFFDLWEFAKLSAAS-- 268
KLG+ A A G +V F ++ C ++ F + E +
Sbjct: 185 G-KLGIPAFGAVGCGIATAIVNWFMCILMIAYCKNARNQRDLKVFAKILEKPNFTTLKKL 243
Query: 269 ---GVMLCLEVWYDKVLMLMTGNLHN--AKKFVEALTICLTLNIWELMFPLGFLAATGVR 323
G + + ++ + L +T L + V + I L + + M P+ A +
Sbjct: 244 LNLGFPIAVALFCEVALFALTALLLSPLGTDIVASHQIALNTSSFLFMLPMSLGMAATIL 303
Query: 324 VANELGAGNGQAAKFASAVAVVTSIIISVFFWLLIMIFRRQIGYLFTSSELVIEEVNKLS 383
V LG G AK S A++ ++I+V L +IFR +I +F VI L
Sbjct: 304 VGQRLGEGAADKAKQVSYSALIVGLLIAVITATLTVIFRVEIAEIFVKDRDVIAMAGTLL 363
Query: 384 PLLGFTILLNSVQPVLSGVAIGSGWQKYVAYIDLGCYYLIGMPLGFLMG----FVFQFGV 439
+ ++VQ V G G K + YI L CY+++GMP+G+ + + G
Sbjct: 364 LIAALYQFSDTVQVVAGGALRGYKDTKAILYITLFCYWVVGMPMGYTLARTDLLMPALGA 423
Query: 440 EGLWAGLVCGGPAIQTLIL 458
EG W G V TL++
Sbjct: 424 EGFWIGFVVSLTIAATLLM 442
>YHJ2_YEAST (P38767) Hypothetical 64.2 kDa protein in SLT2-PUT2
intergenic region
Length = 581
Score = 87.0 bits (214), Expect = 1e-16
Identities = 91/376 (24%), Positives = 164/376 (43%), Gaps = 17/376 (4%)
Query: 47 PAIFNRVSNYSMLVITQVFAGHLGDMELAATSIAMNLILGLDLGIMLGMSSALETLCGQA 106
P IF + S+ + + HLG EL ++ L + G+ + L+TLC QA
Sbjct: 174 PLIFTFILQNSLSLASIFSVSHLGTKELGGVTLGSMTANITGLAAIQGLCTCLDTLCAQA 233
Query: 107 FGAKQFNMLGIYMQRSWIVLFITGI-LLLPLFIFATPILNFFGQPQEISELAG---VISM 162
+GAK ++++G+ +QR ++ + + ++ F+++ IL +E+ LA ++
Sbjct: 234 YGAKNYHLVGVLVQRCAVITILAFLPMMYVWFVWSEKILALMIPERELCALAANYLRVTA 293
Query: 163 WLIPTHVTYAFFFPLYFFLQSQLKNNIIGWVSLVALLVHVFLCWLVVVKFKLGVIALVAS 222
+ +P + F FLQ Q + V V ++ + +L+V K+G+ L A
Sbjct: 294 FGVP---GFILFECGKRFLQCQGIFHASTIVLFVCAPLNALMNYLLVWNDKIGIGYLGAP 350
Query: 223 GNVA--WIVLVFGFFGYAVLC---GCPL-TWTGF--SMEAFFDLWEFAKLSAASGVMLCL 274
+V + ++ G YA+ PL W G +AF + + L+ VM+
Sbjct: 351 LSVVINYWLMTLGLLIYAMTTKHKERPLKCWNGIIPKEQAFKNWRKMINLAIPGVVMVEA 410
Query: 275 EVWYDKVLMLMTGNLHNAKKFVEALTICLTLNIWELMFPLGFLAATGVRVANELGAGNGQ 334
E +VL + H + A +I T+ P +T RVAN +GA
Sbjct: 411 EFLGFEVLTIFAS--HLGTDALGAQSIVATIASLAYQVPFSISVSTSTRVANFIGASLYD 468
Query: 335 AAKFASAVAVVTSIIISVFFWLLIMIFRRQIGYLFTSSELVIEEVNKLSPLLGFTILLNS 394
+ V+++ S + S +I ++ QI LF++ V++ V PLL F L ++
Sbjct: 469 SCMITCRVSLLLSFVCSSMNMFVICRYKEQIASLFSTESAVVKMVVDTLPLLAFMQLFDA 528
Query: 395 VQPVLSGVAIGSGWQK 410
+G G G QK
Sbjct: 529 FNASTAGCLRGQGRQK 544
>NORM_BACSU (O31855) Probable multidrug resistance protein norM
(Na(+)/drug antiporter) (Multidrug-efflux transporter)
Length = 452
Score = 86.7 bits (213), Expect = 1e-16
Identities = 93/423 (21%), Positives = 178/423 (41%), Gaps = 19/423 (4%)
Query: 39 KKLWHIAGPAIFNRVSNYSMLVITQVFAGHLGDMELAATSIAMNLILGLDLGIMLGMSSA 98
K+L HI P + + + V +G + +LA +I +L + G+ G+ A
Sbjct: 12 KQLLHILIPIFITQAGLSLITFLDTVMSGKVSPADLAGVAIGSSLWTPVYTGLA-GILMA 70
Query: 99 LETLCGQAFGAKQFNMLGIYMQRSWIVLFITGILLLPLFIFATPI----LNFFGQPQEIS 154
+ + Q GA++ + + ++ V + I +L + A + LN +I+
Sbjct: 71 VTPIVAQLLGAEKKQKIPFTVLQAVYVAALLSIAVLVIGYAAVDLILGRLNLDIHVHQIA 130
Query: 155 E-LAGVISMWLIPTHVTYAFFFPLYFFLQSQLKNNIIGWVSLVALLVHVFLCWLVVV-KF 212
+ G +S+ + P V + L F+ S K + ++L +L ++ L ++ + KF
Sbjct: 131 KHFLGFLSLGIFPLFV----YTVLRSFIDSLGKTRVTMMITLSSLPINFVLNYVFIFGKF 186
Query: 213 KL----GVIALVASGNVAWIVLVFGFFGYAVLCGCPLTWTGFSMEAFFDLWEFAKLSAAS 268
+ GV A +AS W + + FF + P + G + + W+ K
Sbjct: 187 GMPALGGVGAGLASALTYWCICIISFF--IIHKNAPFSEYGIFLTMYKFSWKACKNLLKI 244
Query: 269 GVMLCLEVWYDKVLMLMTGNLHNAKKFVEALTICLTLNIWELMF--PLGFLAATGVRVAN 326
G+ + V+++ + L + V + +N L++ PL A + V
Sbjct: 245 GLPIGFAVFFETSIFAAVTLLMSHFHTVTIASHQAAMNFASLLYMLPLSVSMALTIVVGF 304
Query: 327 ELGAGNGQAAKFASAVAVVTSIIISVFFWLLIMIFRRQIGYLFTSSELVIEEVNKLSPLL 386
E GA + A+ S + ++ +I S+F I++FR QI ++TS V+
Sbjct: 305 EAGAARFKDARSYSLIGIMMAIGFSLFTAACILLFREQIAGMYTSDPDVLRLTQHFLIYA 364
Query: 387 GFTILLNSVQPVLSGVAIGSGWQKYVAYIDLGCYYLIGMPLGFLMGFVFQFGVEGLWAGL 446
F L ++V + G G Y Y++IG+P+G+++G G G W GL
Sbjct: 365 LFFQLSDAVAAPIQGALRGYKDVNYTLAAAFVSYWVIGLPVGYMVGTFTSLGAFGYWIGL 424
Query: 447 VCG 449
+ G
Sbjct: 425 IAG 427
>NORM_VIBPA (O82855) Multidrug resistance protein norM (Na(+)/drug
antiporter) (Multidrug-efflux transporter)
Length = 456
Score = 82.4 bits (202), Expect = 2e-15
Identities = 102/453 (22%), Positives = 182/453 (39%), Gaps = 37/453 (8%)
Query: 33 RVWNESKKLWHIAGPAIFNRVSNYSMLVITQVFAGHLGDMELAATSIAMNLILGLDLGIM 92
R E+ L +A P + V+ M + V AG + ++AA S+A ++ L L
Sbjct: 3 RYKEEASSLIKLATPVLIASVAQTGMGFVDTVMAGGVSATDMAAVSVASSIWLPSIL-FG 61
Query: 93 LGMSSALETLCGQAFGAKQFNMLGIYMQRSWIVLFITGILLLPLFIFATPILNFFGQPQE 152
+G+ AL + Q G+ + + +Q+ ++ + I PI+ Q Q
Sbjct: 62 IGLLMALVPVVAQLNGSARREKIPFEIQQGVVLALLISI----------PIIGVLLQTQF 111
Query: 153 ISELAGVISMWLIPT-HVTYAFFFPLYFFLQSQLKNNIIGWVSL---------VALLVHV 202
I +L V ++ T +A F + FL Q + +SL + LL+++
Sbjct: 112 ILQLMDVEAVMAGKTVGYIHAVIFAVPAFLLFQTLRSFTDGMSLTKPAMVIGFIGLLLNI 171
Query: 203 FLCWLVVV-KFKLGVIALVASGNVAWIV--LVFGFFGYAVLCGCPLTWTGFSMEAFFDLW 259
L W+ V KF + V G IV ++F V+ L E W
Sbjct: 172 PLNWIFVYGKFGAPELGGVGCGVATTIVYWVMFALLLAYVMTSSRLKSINVFGEYHKPQW 231
Query: 260 E----FAKLSAASGVMLCLEVWYDKVLMLMTGNLHNAKKFVEALTICLTLNIWELMFPLG 315
+ KL L EV V+ L+ L V A + + + M P+
Sbjct: 232 KAQVRLFKLGFPVAAALFFEVTLFAVVALLVSPL--GPIIVAAHQVAINFSSLVFMLPMS 289
Query: 316 FLAATGVRVANELGAGNGQAAKFASAVAVVTSIIISVFFWLLIMIFRRQIGYLFTSSELV 375
AA +RV + LG N A+ AS V ++ + ++ ++ ++ R I L+T++ V
Sbjct: 290 VGAAVSIRVGHRLGEENVDGARVASRVGIMVGLALATITAIITVLSRELIAELYTNNPEV 349
Query: 376 IEEVNKLSPLLGFTILLNSVQPVLSGVAIGSGWQKYVAYIDLGCYYLIGMPLGFLMG--- 432
I +L ++VQ + +G G + + Y+++G+P G+++G
Sbjct: 350 ISLAMQLLLFAAVYQCTDAVQVIAAGALRGYKDMRAIFNRTFIAYWILGLPTGYILGRTD 409
Query: 433 -FVFQFGVEGLWAGLVCGGPAIQTLI---LAWV 461
V G +G W G + G A ++ L W+
Sbjct: 410 WIVEPMGAQGFWLGFIIGLTAAALMLGVRLRWM 442
>NORM_DEIRA (Q9RY44) Probable multidrug resistance protein norM
(Na(+)/drug antiporter) (Multidrug-efflux transporter)
Length = 451
Score = 80.5 bits (197), Expect = 9e-15
Identities = 110/434 (25%), Positives = 179/434 (40%), Gaps = 39/434 (8%)
Query: 37 ESKKLWHIAGPAIFNRVSNYSMLVITQVFAGHLGDMELAATSIA---MNLILGLDLGIML 93
E + L +AGP + ++ + ++ +I G LG+ ELAA + A L+ + +G+ML
Sbjct: 14 ELRALLRLAGPVVVSQFAANALALIATAVIGRLGERELAAAAYANAAYYLVFIMVVGVML 73
Query: 94 GMSSALETLCGQAFGAKQFNMLGIYMQRSWIVLFITGILLLPLFIFATPILNFFGQPQEI 153
++ + QA GA + + + + ++LPL + +L F
Sbjct: 74 SVAPRV----AQAHGAGDARGVARALGGGLRLALLLSAVMLPLMWALSFVLPNFAPAGVS 129
Query: 154 SELAG----VISMWLIPTHVTYAFFFPLYFFLQSQLKNNIIGWVSLV----ALLVHVFLC 205
+L V S+ ++P F L L+ K + V+L ALLV L
Sbjct: 130 RDLVAAYLRVYSLGMLPNLA----FIALRGTLEGTGKPGAVTGVALTGVVWALLVAPALA 185
Query: 206 WLVVVKFKLGVI-ALVASGNVAWIV--LVFGFFGYAVLCGCPLTWTGFSMEAFFDL-WEF 261
+ +LG+ A AS + AWI+ L++ V PL G + A F L W
Sbjct: 186 FGWGPLPRLGLAGAAGASASAAWIMAALLWPLARRRVAYAGPLGPLGDEVRALFRLGWPI 245
Query: 262 AKLSAASGVMLCLEVWYDKVLMLMTGNLHNAKKFVEALTICLTLNIWELMFPLGFLAATG 321
A G M + +LM G A V TI M PLG +ATG
Sbjct: 246 GLTLGAEGGMFSVTT----LLMARFGPEVLAAHNVTMQTITAFF-----MVPLGIASATG 296
Query: 322 VRVANELGAGNGQAAKFASAVAVVTSIIISVFFWLLIMIFRRQIGYLF------TSSELV 375
VRV E GAG A+ A V + S + + F ++ + R + +F ++ L+
Sbjct: 297 VRVGTEAGAGRLAQARRAGLVGLGLSSAVMLTFAVIELAAPRTVFSVFVNVNDPANAGLI 356
Query: 376 IEEVNKLSPLLGFTILLNSVQPVLSGVAIGSGWQKYVAYIDLGCYYLIGMPLGFLMGFVF 435
LS + L++ +Q +G G + + L Y+++G+ LG ++ V
Sbjct: 357 AAATGFLS-IAALFQLMDGLQVTANGALRGLQDTRVPLLVSLVAYWVVGLGLGSVLSSVA 415
Query: 436 QFGVEGLWAGLVCG 449
G GLW GL G
Sbjct: 416 GLGARGLWFGLTAG 429
>NOM1_PSEAE (Q9I3Y3) Probable multidrug resistance protein norM 1
(Na(+)/drug antiporter) (Multidrug-efflux transporter)
Length = 477
Score = 78.6 bits (192), Expect = 3e-14
Identities = 110/468 (23%), Positives = 178/468 (37%), Gaps = 71/468 (15%)
Query: 31 GRRVWNESKKLWHIAGPAIFNRVSNYSMLVITQVFAGHLGDMELAATSIAMNLILGLDLG 90
G R+ E K+L +A P + +++ +M + V AG +LAA ++ ++ + + L
Sbjct: 11 GLRIRAELKELLTLAAPIMIAQLATTAMGFVDAVMAGRASPHDLAAVALGNSIWIPMFL- 69
Query: 91 IMLGMSSALETLCGQAFGAKQFNMLG-IYMQRSWIVLFITGILLLPLFIFATPILNFFGQ 149
+M G A Q GA G + Q W+ L I + L+ + PIL G
Sbjct: 70 LMTGTLLATTAKVAQRHGAGDQPGTGPLVRQALWLALLIGPLSGAVLWWLSEPIL---GL 126
Query: 150 PQEISELAGVISMWLIPTHVTYAFFFPLYFFLQSQLKNNIIGWVSLVALLVHVFLCWL-- 207
+ EL G ++L A FP A L HV C+
Sbjct: 127 MKVRPELIGPSLLYL----KGIALGFP-------------------AAALYHVLRCYTNG 163
Query: 208 ---VVVKFKLGVIALVASGNVAWIVLVFGFFGYAVLCGCPLTWTGFSMEAF--------- 255
LG+ L+ + + + L++G FG + G W S+ F
Sbjct: 164 LGRTRPSMVLGIGGLLLNIPINY-ALIYGHFGMPKMGGPGCGWATGSVMWFMFLGMLFWV 222
Query: 256 -----------FDLWEF---------AKLSAASGVMLCLEVWYDKVLMLMTGNLHNAKKF 295
F WE+ + G+ + E V+ L+ G L +
Sbjct: 223 NKASIYRASQLFSRWEWPDRATIGPLVAVGLPIGIAVFAESSIFSVIALLIGGLD--ENV 280
Query: 296 VEALTICLTLNIWELMFPLGFLAATGVRVANELGAGNGQAAKFASAVAVVTSIIISVFFW 355
V I L + M P A VRV + LGAG + A+FA+ V + ++ +
Sbjct: 281 VAGHQIALNFSALVFMIPYSLGMAVTVRVGHNLGAGLPRDARFAAGVGMAAALGYACVSA 340
Query: 356 LLIMIFRRQIGYLFTSSELVIEEVNKLSPLLGFTILLNSVQPVLSGVAIGSGWQKYVAYI 415
L+++ R QI +++ VI L +++Q +G G + +
Sbjct: 341 SLMLLLREQIAAMYSPDPAVIAIAASLIVFSALFQFSDALQVTAAGALRGYQDTRVTMIM 400
Query: 416 DLGCYYLIGMPLGFLMGFVFQF----GVEGLWAGLVCG--GPAIQTLI 457
L Y+ IG+P+G+ +G F G GLW GLV G G AI I
Sbjct: 401 TLFAYWGIGLPVGYSLGLTDWFQEPTGPRGLWQGLVVGLTGAAIMLCI 448
>NORM_NEIMA (Q9JV27) Probable multidrug resistance protein norM
(Na(+)/drug antiporter) (Multidrug-efflux transporter)
Length = 459
Score = 75.9 bits (185), Expect = 2e-13
Identities = 94/451 (20%), Positives = 184/451 (39%), Gaps = 40/451 (8%)
Query: 37 ESKKLWHIAGPAIFNRVSNYSMLVITQVFAGHLGDMELAATSIAMNLILGLDLGIMLGMS 96
E + L +A P + +V+ + + V AG G +LAA ++ + + + M G+
Sbjct: 16 EVRLLTALALPMLLAQVAQVGIGFVDTVMAGGAGKEDLAAVALGSSAFATVYITFM-GIM 74
Query: 97 SALETLCGQAFGAKQFNMLG-IYMQRSWIVLFITGILLLPLFIFATPILNFFGQPQEISE 155
+AL + Q +GA + + +G Q W LF+ ++ ++ TP N+ +
Sbjct: 75 AALNPMIAQLYGAGKTDEVGETGRQGIWFGLFLGVFGMVLMWAAITPFRNWLTLSDYVE- 133
Query: 156 LAGVISMWLIPTHVTYAFFF---PLYFFLQSQLKNNIIGWVSLVALLVHVFLCWLVVVKF 212
G ++ +++ T + L+ + S + +I VS A +++V L ++ V
Sbjct: 134 --GTMAQYMLFTSLAMPAAMVHRALHAYASSLNRPRLIMLVSFAAFVLNVPLNYIFVYG- 190
Query: 213 KLGVIALVASGNVAWIVLVFGFFGYAVLCGCPLTWTGFSMEAFF---------------- 256
K G+ AL +G + VF F A+ W + E FF
Sbjct: 191 KFGMPALGGAGCGLATMAVFWFSALAL-------WIYIAKENFFRPFGLTAKFGKPDWAV 243
Query: 257 --DLWEFAKLSAASGVMLCLEVWYDKVLMLMTGNLHNAKKFVEALTICLTLNIWELMFPL 314
+W K+ A G+ LE ++ + + +V A + ++L+ M P
Sbjct: 244 FKQIW---KIGAPIGLSYFLEASAFSFIVFLIAPF--GEDYVAAQQVGISLSGILYMIPQ 298
Query: 315 GFLAATGVRVANELGAGNGQAAKFASAVAVVTSIIISVFFWLLIMIFRRQIGYLFTSSEL 374
+A VR+ LG A++ S V++V+ +++V L +++FR + ++ +
Sbjct: 299 SVGSAGTVRIGFSLGRREFSRARYISGVSLVSGWMLAVITVLSLVLFRSPLVSMYNNDPA 358
Query: 375 VIEEVNKLSPLLGFTILLNSVQPVLSGVAIGSGWQKYVAYIDLGCYYLIGMPLGFLMGFV 434
V+ + G + Q + S G K +I ++ G+ G+L+ +
Sbjct: 359 VLSIAATVLLFAGLFQPADFTQCIASYALRGYKVTKVPMFIHAAAFWGCGLLPGYLLAYR 418
Query: 435 FQFGVEGLWAGLVCGGPAIQTLILAWVTIRC 465
F G+ G W L+ I + L W C
Sbjct: 419 FDMGIYGFWTALI-ASLTIAAIALVWCLELC 448
>NORM_NEIMB (Q9K015) Probable multidrug resistance protein norM
(Na(+)/drug antiporter) (Multidrug-efflux transporter)
Length = 459
Score = 75.1 bits (183), Expect = 4e-13
Identities = 94/451 (20%), Positives = 183/451 (39%), Gaps = 40/451 (8%)
Query: 37 ESKKLWHIAGPAIFNRVSNYSMLVITQVFAGHLGDMELAATSIAMNLILGLDLGIMLGMS 96
E + L +A P + +V+ + + V AG G +LAA ++ + + + M G+
Sbjct: 16 EVRLLTTLALPMLLAQVAQVGIGFVDTVMAGGAGKEDLAAVALGSSAFATVYITFM-GIM 74
Query: 97 SALETLCGQAFGAKQFNMLG-IYMQRSWIVLFITGILLLPLFIFATPILNFFGQPQEISE 155
+AL + Q +GA + + +G Q W LF+ ++ ++ TP N+ +
Sbjct: 75 AALNPMIAQLYGAGKTDEVGETGRQGIWFGLFLGVFGMVLMWAAITPFRNWLTLSDYVE- 133
Query: 156 LAGVISMWLIPTHVTYAFFF---PLYFFLQSQLKNNIIGWVSLVALLVHVFLCWLVVVKF 212
G ++ +++ T + L+ + S + +I VS A +++V L ++ V
Sbjct: 134 --GTMAQYMLFTSLAMPAAMVHRALHAYTSSLNRPRLIMLVSFAAFVLNVPLNYIFVYG- 190
Query: 213 KLGVIALVASGNVAWIVLVFGFFGYAVLCGCPLTWTGFSMEAFF---------------- 256
K G+ AL +G + VF F A+ W + E FF
Sbjct: 191 KFGMPALGGAGCGLATMAVFWFSALAL-------WIYIAKENFFRPFGLTAKFGKPDWAV 243
Query: 257 --DLWEFAKLSAASGVMLCLEVWYDKVLMLMTGNLHNAKKFVEALTICLTLNIWELMFPL 314
+W K+ A G+ LE ++ + + +V A + ++L+ M P
Sbjct: 244 FKQIW---KIGAPIGLSYFLEASAFSFIVFLIAPF--GEDYVAAQQVGISLSGILYMIPQ 298
Query: 315 GFLAATGVRVANELGAGNGQAAKFASAVAVVTSIIISVFFWLLIMIFRRQIGYLFTSSEL 374
+A VR+ LG A++ S V++V +++V L +++FR + ++ +
Sbjct: 299 SVGSAGTVRIGFSLGRREFSRARYISGVSLVLGWMLAVITVLSLVLFRSPLVSMYNNDPA 358
Query: 375 VIEEVNKLSPLLGFTILLNSVQPVLSGVAIGSGWQKYVAYIDLGCYYLIGMPLGFLMGFV 434
V+ + G + Q + S G K +I ++ G+ G+L+ +
Sbjct: 359 VLSIAATVLLFAGLFQPADFTQCIASYALRGYKVTKVPMFIHAAAFWGCGLLPGYLLAYR 418
Query: 435 FQFGVEGLWAGLVCGGPAIQTLILAWVTIRC 465
F G+ G W L+ I + L W C
Sbjct: 419 FNMGIYGFWTALI-ASLTIAAIALVWCLELC 448
>NORM_BACHD (Q9KEJ2) Probable multidrug resistance protein norM
(Na(+)/drug antiporter) (Multidrug-efflux transporter)
Length = 458
Score = 71.6 bits (174), Expect = 4e-12
Identities = 86/423 (20%), Positives = 177/423 (41%), Gaps = 14/423 (3%)
Query: 47 PAIFNRVSNYSMLVITQVFAGHLGDMELAATSIAMNLILGLDLGIMLGMSSALETLCGQA 106
P + ++ Y+M V +G G +LA +I +L + + G+ G+ AL + Q+
Sbjct: 20 PILITQIGLYAMNFFDTVMSGQAGANDLAGVAIGSSLWVPVFTGLN-GVLLALTPIIAQS 78
Query: 107 FGA-KQFNMLGIYMQRSWIVLFITGILLLPLFIFATPILNFFGQPQEISELAGVISMWLI 165
GA K+ ++ +++Q ++ + I+ ++L + PIL+ E+ +A + L
Sbjct: 79 IGAEKRDDVPYVFLQGLYLSIAISIAVILIGAVVLDPILSAMSLEDEVGRIAKEYLIGLA 138
Query: 166 PTHVTYAFFFPLYFFLQSQLKNNIIGWVSLVALLVHVFLCWLVVVKFKLGVIAL--VASG 223
V + + + S + + +++L++L +++F ++++ KLG L V +G
Sbjct: 139 FGIVPLFIYTTIRCLIDSLGETRVTMFITLLSLPINIFFNYVLIFG-KLGFPRLGGVGAG 197
Query: 224 NVAWIVLVFGFFGYAVLCGCPLTWTGFSM-----EAFFDLW-EFAKLSAASGVMLCLEVW 277
+ I F V+ +T F + W E L G + E
Sbjct: 198 YASAITYWFILAVAIVVVVKVRPFTDFQLFKKLYHVSLKKWKEILLLGLPIGFTIFFETS 257
Query: 278 YDKVLMLMTGNLHNAKKFVEALTICLTLNIWELMFPLGFLAATGVRVANELGAGNGQAAK 337
+ L+ A + A + + M PL + V E+GA + A+
Sbjct: 258 IFAAVTLLMSTFDTAT--IAAHQAAVNFASFLYMIPLSIAFTLTIAVGYEVGAKRVEDAR 315
Query: 338 FASAVAVVTSIIISVFFWLLIMIFRRQIGYLFTSSELVIEEVNKLSPLLGFTILLNSVQP 397
S + + ++I+ + ++I + R + L+T+ V + + F L +++
Sbjct: 316 QYSRLGITFALIMGLVAGVIIYVLRAPVASLYTNDSQVAWLIQQFLIYSIFFQLSDALAT 375
Query: 398 VLSGVAIGSGWQKYVAYIDLGCYYLIGMPLGFLMGFVFQFGVEGLWAGLVCGGPAIQTLI 457
+ GV G + L +++IG+P G+L+ G G W GL+ G A +
Sbjct: 376 PIQGVLRGHKDVNVPFVMALVSFWIIGLPTGYLLANFSPLGPYGYWIGLIT-GLASCAIA 434
Query: 458 LAW 460
L+W
Sbjct: 435 LSW 437
>NORM_ECOLI (P37340) Multidrug resistance protein norM (Na(+)/drug
antiporter) (Multidrug-efflux transporter)
Length = 457
Score = 70.9 bits (172), Expect = 7e-12
Identities = 88/430 (20%), Positives = 173/430 (39%), Gaps = 23/430 (5%)
Query: 36 NESKKLWHIAGPAIFNRVSNYSMLVITQVFAGHLGDMELAATSIAMNLILGLDL---GIM 92
+E++ L +A P I +++ +M + V AG ++AA +I ++ L L G++
Sbjct: 6 SEARLLLALAIPVILAQIAQTAMGFVDTVMAGGYSATDMAAVAIGTSIWLPAILFGHGLL 65
Query: 93 LGMSSALETLCGQAFGAKQFNMLGIYMQRSWIVLFITGILLLPLFIFATPILNFFGQPQE 152
L ++ + L G ++ + Q W+ F++ +++L L+ I +
Sbjct: 66 LALTPVIAQLNGSG---RRERIAHQVRQGFWLAGFVSVLIMLVLWNAGYIIRSMENIDPA 122
Query: 153 ISELAGVISMWLIPTHVTYAFFFPLYFFLQSQLKNNIIGWVSLVALLVHVFLCWLVVVKF 212
+++ A L+ Y FF + K + + LLV++ + ++ F
Sbjct: 123 LADKAVGYLRALLWGAPGYLFFQVARNQCEGLAKTKPGMVMGFIGLLVNIPVNYI----F 178
Query: 213 KLGVIALVASGNVAWIVLVFGFFGYAVLCGCPLTWTGFSMEAFFDLWEFAKLSAAS---- 268
G + G V V + L SM + AK A
Sbjct: 179 IYGHFGMPELGGVGCGVATAAVYWVMFLAMVSYIKRARSMRDIRNEKGTAKPDPAVMKRL 238
Query: 269 ---GVMLCLEVWYDKVLMLMTGNLHNAKKFVEALTICLTLNIWELMF--PLGFLAATGVR 323
G+ + L ++++ L + L + V+ + LN LMF P+ AA +R
Sbjct: 239 IQLGLPIALALFFEVTLFAVVALLVSPLGIVDVAGHQIALNFSSLMFVLPMSLAAAVTIR 298
Query: 324 VANELGAGNGQAAKFASAVAVVTSIIISVFFWLLIMIFRRQIGYLFTSSELVIEEVNKLS 383
V LG G+ A+ A+ ++ + ++ + + R QI L+ + V+ L
Sbjct: 299 VGYRLGQGSTLDAQTAARTGLMVGVCMATLTAIFTVSLREQIALLYNDNPEVVTLAAHLM 358
Query: 384 PLLGFTILLNSVQPVLSGVAIGSGWQKYVAYIDLGCYYLIGMPLGFLMGF----VFQFGV 439
L + +S+Q + SG+ G + + YI Y+++G+P G+++ V G
Sbjct: 359 LLAAVYQISDSIQVIGSGILRGYKDTRSIFYITFTAYWVLGLPSGYILALTDLVVEPMGP 418
Query: 440 EGLWAGLVCG 449
G W G + G
Sbjct: 419 AGFWIGFIIG 428
>NORM_ECOL6 (Q8FH68) Multidrug resistance protein norM (Na(+)/drug
antiporter) (Multidrug-efflux transporter)
Length = 457
Score = 70.9 bits (172), Expect = 7e-12
Identities = 88/430 (20%), Positives = 173/430 (39%), Gaps = 23/430 (5%)
Query: 36 NESKKLWHIAGPAIFNRVSNYSMLVITQVFAGHLGDMELAATSIAMNLILGLDL---GIM 92
+E++ L +A P I +++ +M + V AG ++AA +I ++ L L G++
Sbjct: 6 SEARLLLALAIPVILAQIAQTAMGFVDTVMAGGYSATDMAAVAIGTSIWLPAILFGHGLL 65
Query: 93 LGMSSALETLCGQAFGAKQFNMLGIYMQRSWIVLFITGILLLPLFIFATPILNFFGQPQE 152
L ++ + L G ++ + Q W+ F++ +++L L+ I +
Sbjct: 66 LALTPVIAQLNGSG---RRERIAHQVRQGFWLAGFVSVLIMLVLWNAGYIIRSMQNIDPA 122
Query: 153 ISELAGVISMWLIPTHVTYAFFFPLYFFLQSQLKNNIIGWVSLVALLVHVFLCWLVVVKF 212
+++ A L+ Y FF + K + + LLV++ + ++ F
Sbjct: 123 LADKAVGYLRALLWGAPGYLFFQVARNQCEGLAKTKPGMVMGFIGLLVNIPVNYI----F 178
Query: 213 KLGVIALVASGNVAWIVLVFGFFGYAVLCGCPLTWTGFSMEAFFDLWEFAKLSAAS---- 268
G + G V V + L SM + AK A
Sbjct: 179 IYGHFGMPELGGVGCGVATAAVYWVMFLAMVSYIKRARSMRDIRNEKGTAKPDPAVMKRL 238
Query: 269 ---GVMLCLEVWYDKVLMLMTGNLHNAKKFVEALTICLTLNIWELMF--PLGFLAATGVR 323
G+ + L ++++ L + L + V+ + LN LMF P+ AA +R
Sbjct: 239 IQLGLPIALALFFEVTLFAVVALLVSPLGIVDVAGHQIALNFSSLMFVLPMSLAAAVTIR 298
Query: 324 VANELGAGNGQAAKFASAVAVVTSIIISVFFWLLIMIFRRQIGYLFTSSELVIEEVNKLS 383
V LG G+ A+ A+ ++ + ++ + + R QI L+ + V+ L
Sbjct: 299 VGYRLGQGSTLDAQTAARTGLMVGVCMATLTAIFTVSLREQIALLYNDNPEVVTLAAHLM 358
Query: 384 PLLGFTILLNSVQPVLSGVAIGSGWQKYVAYIDLGCYYLIGMPLGFLMGF----VFQFGV 439
L + +S+Q + SG+ G + + YI Y+++G+P G+++ V G
Sbjct: 359 LLAAVYQISDSIQVIGSGILRGYKDTRSIFYITFTAYWVLGLPSGYILALTDLVVEPMGP 418
Query: 440 EGLWAGLVCG 449
G W G + G
Sbjct: 419 AGFWIGFIIG 428
>NORM_ECO57 (P58164) Multidrug resistance protein norM (Na(+)/drug
antiporter) (Multidrug-efflux transporter)
Length = 457
Score = 70.9 bits (172), Expect = 7e-12
Identities = 88/430 (20%), Positives = 173/430 (39%), Gaps = 23/430 (5%)
Query: 36 NESKKLWHIAGPAIFNRVSNYSMLVITQVFAGHLGDMELAATSIAMNLILGLDL---GIM 92
+E++ L +A P I +++ +M + V AG ++AA +I ++ L L G++
Sbjct: 6 SEARLLLALAIPVILAQIAQTAMGFVDTVMAGGYSATDMAAVAIGTSIWLPAILFGHGLL 65
Query: 93 LGMSSALETLCGQAFGAKQFNMLGIYMQRSWIVLFITGILLLPLFIFATPILNFFGQPQE 152
L ++ + L G ++ + Q W+ F++ +++L L+ I +
Sbjct: 66 LALTPVIAQLNGSG---RRERIAHQVRQGFWLAGFVSVLIMLVLWNAGYIIRSMENIDPA 122
Query: 153 ISELAGVISMWLIPTHVTYAFFFPLYFFLQSQLKNNIIGWVSLVALLVHVFLCWLVVVKF 212
+++ A L+ Y FF + K + + LLV++ + ++ F
Sbjct: 123 LADKAVGYLRALLWGAPGYLFFQVARNQCEGLAKTKPGMVMGFIGLLVNIPVNYI----F 178
Query: 213 KLGVIALVASGNVAWIVLVFGFFGYAVLCGCPLTWTGFSMEAFFDLWEFAKLSAAS---- 268
G + G V V + L SM + AK A
Sbjct: 179 IYGHFGMPELGGVGCGVATAAVYWVMFLAMVSYIKRARSMRDIRNEKGTAKPDPAVMKRL 238
Query: 269 ---GVMLCLEVWYDKVLMLMTGNLHNAKKFVEALTICLTLNIWELMF--PLGFLAATGVR 323
G+ + L ++++ L + L + V+ + LN LMF P+ AA +R
Sbjct: 239 IQLGLPIALALFFEVTLFAVVALLVSPLGIVDVAGHQIALNFSSLMFVLPMSLAAAVTIR 298
Query: 324 VANELGAGNGQAAKFASAVAVVTSIIISVFFWLLIMIFRRQIGYLFTSSELVIEEVNKLS 383
V LG G+ A+ A+ ++ + ++ + + R QI L+ + V+ L
Sbjct: 299 VGYRLGQGSTLDAQTAARTGLMVGVCMATLTAIFTVSLREQIALLYNDNPEVVTLAAHLM 358
Query: 384 PLLGFTILLNSVQPVLSGVAIGSGWQKYVAYIDLGCYYLIGMPLGFLMGF----VFQFGV 439
L + +S+Q + SG+ G + + YI Y+++G+P G+++ V G
Sbjct: 359 LLAAVYQISDSIQVIGSGILRGYKDTRSIFYITFTAYWVLGLPSGYILALTDLVVEPMGP 418
Query: 440 EGLWAGLVCG 449
G W G + G
Sbjct: 419 AGFWIGFIIG 428
>NORM_XYLFT (Q879Z5) Probable multidrug resistance protein norM
(Na(+)/drug antiporter) (Multidrug-efflux transporter)
Length = 469
Score = 70.1 bits (170), Expect = 1e-11
Identities = 91/436 (20%), Positives = 179/436 (40%), Gaps = 13/436 (2%)
Query: 33 RVWNESKKLWHIAGPAIFNRVSNYSMLVITQVFAGHLGDMELAATSIAMNLILGLDLGIM 92
R +E + +A P + VS + + V AGH + LAA++I L L L + +
Sbjct: 25 RFGSEVRPTLLLALPLVLGHVSTGLIGFVLNVIAGHHSTVTLAASTIGTAL-LWLPMLVP 83
Query: 93 LGMSSALETLCGQAFGAKQFNMLG-IYMQRSWIVLFITGILLLPLFIFATPILNFFGQPQ 151
+G +L L Q GA++ +G ++ Q W+ + + G+++ +L FG
Sbjct: 84 MGTLISLTVLVSQLHGAERERDIGPLFRQALWLAMLL-GLVMFTFLSVVPALLPLFGIVP 142
Query: 152 EISELAGVISMWLIPTHVTYAFFFPLYFFLQSQ---LKNNIIGWVSLVALLVHVFLCWLV 208
+I A + + + +F + +F + ++G+ L+ L+ +
Sbjct: 143 DIVPGAAKFLHVVRWGSLAFPLYFCMRYFCEGMHCTFPTMLLGFGGLLVLVPLSYALTYG 202
Query: 209 VVKF-KLGVIAL-VASGNVAWI-VLVFGFFGYAVLCGCPLT-WTGFSMEAFFDLWEFAKL 264
F + GV L +A+ V W+ +VF + + L + + + + + +
Sbjct: 203 RFGFAEYGVEGLGIATVTVMWLQAVVFALYLWRSRRFAHLQLFAHLELPCWARIRDLLNI 262
Query: 265 SAASGVMLCLEVWYDKVLMLMTGNLHNAKKFVEALTICLTLNIWELMFPLGFLAATGVRV 324
G+ + +E V L+ G + + A I L++ M P+G AT VR+
Sbjct: 263 GLPIGISILMEGGLFIVTTLLIGRFGTDE--IAAHQIALSVAQLCFMIPMGVAEATTVRI 320
Query: 325 ANELGAGNGQAAKFASAVAVVTSIIISVFFWLLIMIFRRQIGYLFTSSELVIEEVNKLSP 384
+ +G + + + I ++++ I +T +V +KL
Sbjct: 321 GHAVGRCDLLVMRRVAWAGYAIVIGTQTLSASVLLLGYDVIVAAYTDDLVVASLASKLLL 380
Query: 385 LLGFTILLNSVQPVLSGVAIGSGWQKYVAYIDLGCYYLIGMPLGFLMGFVFQFGVEGLWA 444
+ +Q + SGV G + + + Y+ +GMPLG +GF ++ G+W
Sbjct: 381 FAAIFQFPDGLQMLSSGVLRGMKDTRVPMLLAMISYWGLGMPLGLGLGFALEWNSRGMWI 440
Query: 445 GLVCGGPAIQTLILAW 460
GL+ G A L+L W
Sbjct: 441 GLIIGLTA-AALLLGW 455
>NORM_XYLFA (Q9PA34) Probable multidrug resistance protein norM
(Na(+)/drug antiporter) (Multidrug-efflux transporter)
Length = 469
Score = 68.2 bits (165), Expect = 5e-11
Identities = 90/436 (20%), Positives = 179/436 (40%), Gaps = 13/436 (2%)
Query: 33 RVWNESKKLWHIAGPAIFNRVSNYSMLVITQVFAGHLGDMELAATSIAMNLILGLDLGIM 92
R +E + +A P + VS + + V AGH + LAA++I L L L + +
Sbjct: 25 RFGSEVRPTLLLALPLVLGHVSTGLIGFVLNVIAGHHSTVTLAASTIGTAL-LWLPMLVP 83
Query: 93 LGMSSALETLCGQAFGAKQFNMLG-IYMQRSWIVLFITGILLLPLFIFATPILNFFGQPQ 151
+G +L L Q GA++ +G ++ Q W+ + + G+++ +L FG
Sbjct: 84 MGTLISLTVLVSQLHGAERERDIGPLFRQALWLAMLL-GLVMFTFLSVVPALLPLFGIVP 142
Query: 152 EISELAGVISMWLIPTHVTYAFFFPLYFFLQSQ---LKNNIIGWVSLVALLVHVFLCWLV 208
+I A + + + +F + +F + ++G+ L+ L+ +
Sbjct: 143 DIVPGAAKFLHVVRWGSLAFPLYFCMRYFCEGMHCTFPTMLLGFGGLLVLVPLSYALTYG 202
Query: 209 VVKF-KLGVIAL-VASGNVAWI-VLVFGFFGYAVLCGCPLT-WTGFSMEAFFDLWEFAKL 264
F + GV L +A+ V W+ +VF + + L + + + + + +
Sbjct: 203 RFGFSEYGVEGLGIATVMVMWLQAVVFALYLWRSRRFAHLQLFAHLELPCWARIRDLLNI 262
Query: 265 SAASGVMLCLEVWYDKVLMLMTGNLHNAKKFVEALTICLTLNIWELMFPLGFLAATGVRV 324
G+ + +E V L+ G + + A I L++ M P+G AT VR+
Sbjct: 263 GLPIGISILMEGGLFIVTTLLIGRFGTDE--IAAHQIALSVAQLCFMIPMGVAEATTVRI 320
Query: 325 ANELGAGNGQAAKFASAVAVVTSIIISVFFWLLIMIFRRQIGYLFTSSELVIEEVNKLSP 384
+ +G + + + I ++++ I +T +V +KL
Sbjct: 321 GHAVGRCDLLVMRRVAWAGYAIVIGTQTLSASVLLLGYDVIVAAYTDDLVVASLASKLLL 380
Query: 385 LLGFTILLNSVQPVLSGVAIGSGWQKYVAYIDLGCYYLIGMPLGFLMGFVFQFGVEGLWA 444
+ +Q + SGV G + + + Y+ +GMPLG +GF ++ G+W
Sbjct: 381 FAAIFQFPDGLQMLSSGVLRGMKDTRVPMLLAMISYWGLGMPLGLGLGFALEWNSRGMWI 440
Query: 445 GLVCGGPAIQTLILAW 460
GL+ G A ++L W
Sbjct: 441 GLIIGLTA-AAVLLGW 455
Database: sprot
Posted date: Nov 25, 2004 10:54 AM
Number of letters in database: 59,974,054
Number of sequences in database: 164,201
Lambda K H
0.328 0.142 0.451
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 55,230,087
Number of Sequences: 164201
Number of extensions: 2262964
Number of successful extensions: 7390
Number of sequences better than 10.0: 70
Number of HSP's better than 10.0 without gapping: 24
Number of HSP's successfully gapped in prelim test: 46
Number of HSP's that attempted gapping in prelim test: 7292
Number of HSP's gapped (non-prelim): 96
length of query: 489
length of database: 59,974,054
effective HSP length: 114
effective length of query: 375
effective length of database: 41,255,140
effective search space: 15470677500
effective search space used: 15470677500
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.8 bits)
S2: 68 (30.8 bits)
Medicago: description of AC119414.1