BLAST2 result
BLASTP 2.2.2 [Dec-14-2001]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= AC148398.1 + phase: 2 /pseudo/partial
(2332 letters)
Database: nr
2,540,612 sequences; 863,360,394 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
ref|NP_176883.3| midasin-related [Arabidopsis thaliana] 1256 0.0
gb|AAD10657.1| Hypothetical protein [Arabidopsis thaliana] gi|25... 698 0.0
gb|AAO53165.1| similar to midasin, a large protein with an N-ter... 317 3e-84
gb|EAA58694.1| hypothetical protein AN6310.2 [Aspergillus nidula... 303 6e-80
emb|CAG62826.1| unnamed protein product [Candida glabrata CBS138... 297 3e-78
emb|CAI20706.1| novel protein similar to human MDN1, midasin hom... 294 3e-77
ref|XP_485364.2| PREDICTED: midasin [Mus musculus] 291 1e-76
ref|NP_013207.1| Huge dynein-related AAA-type ATPase (midasin), ... 290 3e-76
emb|CAG98681.1| unnamed protein product [Kluyveromyces lactis NR... 286 6e-75
emb|CAG82879.1| unnamed protein product [Yarrowia lipolytica CLI... 282 8e-74
emb|CAA20864.1| SPCC737.08 [Schizosaccharomyces pombe] gi|190758... 281 2e-73
gb|EAA77856.1| hypothetical protein FG07258.1 [Gibberella zeae P... 280 3e-73
gb|AAS54563.1| AGR074Cp [Ashbya gossypii ATCC 10895] gi|45201169... 279 9e-73
ref|XP_615168.1| PREDICTED: similar to Midasin (MIDAS-containing... 278 2e-72
ref|XP_419835.1| PREDICTED: similar to Midasin (MIDAS-containing... 275 1e-71
emb|CAI16236.1| MDN1, midasin homolog (yeast) [Homo sapiens] gi|... 271 2e-70
dbj|BAA20761.2| KIAA0301 [Homo sapiens] 271 2e-70
emb|CAH10492.1| hypothetical protein [Homo sapiens] 268 1e-69
ref|XP_518639.1| PREDICTED: MDN1, midasin homolog [Pan troglodytes] 259 1e-66
ref|XP_594023.1| PREDICTED: similar to Midasin (MIDAS-containing... 241 2e-61
>ref|NP_176883.3| midasin-related [Arabidopsis thaliana]
Length = 5336
Score = 1256 bits (3251), Expect = 0.0
Identities = 840/2400 (35%), Positives = 1277/2400 (53%), Gaps = 234/2400 (9%)
Query: 1 ESSHAVKEFWVQSLKCRASLSNLWNCSHHGTYLPKFLLSAARALFQQIIYAHRKSFDADQ 60
E+ +VK++ VQS+K ++ LW S +P LLS AR+LFQQIIY H+KSF+++
Sbjct: 3045 ENVFSVKDYSVQSMKLLSASRYLWKSSQPYQEMPGSLLSIARSLFQQIIYTHQKSFESET 3104
Query: 61 YAAIKYNFSSFERNMATEESIHLVSTLVGSSRHHRLKNSVNKFIVPLLRELYIQSTTTDF 120
+ AIK F + E+ + I + +L+GSS H++LK+ + F+ PL + LY S++ +F
Sbjct: 3105 FVAIKSVFHAIEKKQNKMDGIQNLISLIGSSSHNKLKSVTHSFVGPLAKRLYSDSSSNEF 3164
Query: 121 NFNYTIGCAWAHIGALRIHLLLSYNEVDPVMKYYCKYTQLEETISSLELEIQVRKECGYL 180
N +G AW ++G LR HLL S + +DP MK CK +LEE ISSLEL I+VR ECGYL
Sbjct: 3165 YCN--LGLAWLYLGGLRFHLLNSLDVIDPAMKITCKLLKLEEKISSLELNIKVRGECGYL 3222
Query: 181 SGQFLTVEADKRKAERLEKLQAELRKLQRKIVFRSESWKYKKLMNECDEFLKHIASLEVL 240
SG + D+ L KL+ E ++LQRK++FRS+ KY+ L DEF + L
Sbjct: 3223 SGLLYSGNNDESSEHTLSKLKTEHKRLQRKVIFRSDPKKYQDLRRALDEFAGFLTRPISL 3282
Query: 241 VGNVEAEDLQQVIDRTHSWQETAMCFINRLTDEYTAYNDIIQPIQVAVYEMKFGLSLVLS 300
V ++E D QV+++ +WQETA+ FI+R++ +Y+ Y DI QPIQV+VYEMK GLSL +S
Sbjct: 3283 VNDIEVLDWNQVVEQVFNWQETAISFIDRMSSDYSEYVDITQPIQVSVYEMKLGLSLFVS 3342
Query: 301 SFLEKEYLRKVGHENINLVTDMIYILMRFPRAASWKFISVEDVGVDLHSSYKLDF-GTDF 359
L + L + + ++ V + IY LMRFPR +S + + LH S+ +
Sbjct: 3343 GALLGKLLNRFDIDMVDSVMETIYALMRFPRDSSIASTTYTECLPPLHLSHGANSRAKSL 3402
Query: 360 YLNMGLIERLITLSSGVSADKKVSAMRCRASIYWNILVQIAYSIANAKIIDRESYMLLHK 419
L++GL+ +LI++SS + +K S ++ + ++Y N+ ++ +AN ++D S+ LL K
Sbjct: 3403 GLDVGLLHKLISVSSAEDS-RKASELQLKVALYKNLHARVLQFVANTGLLDEASFELLDK 3461
Query: 420 IFDEFASLWMSMKVYAKSKSDHDAQQFKFKPRAFQIESIMELEIPALANSSATEAFSDWK 479
I+ E A +WM MK AK+K+D+ +KF+ R F+I+S+ME++I AL E+FS+W+
Sbjct: 3462 IYVELARIWMEMKFQAKTKADNLPGLYKFRSRDFKIDSVMEVDISALGKYFPNESFSEWQ 3521
Query: 480 EFSYEEKSA---DNMESSEECEILDEEWKHLEESILDNVVLIHSQLFGSGDLVQAPGIFE 536
E+ ++ + D ++ E L+++W ++E LD++ H++LFG DL + G F
Sbjct: 3522 EYLADDDTKNVKDMTHIDQDEENLEDDWDLIQEH-LDSIYSTHNELFGFCDLSEKSGRFC 3580
Query: 537 ISDEDRLHSFSESYKLGINLIKGAHSSNLASLDAKLIPEHLFYLSIDYRRKFHSSSKSAN 596
I+D RL SF++SY+LG+++IKG +SLDAKL+PEHL L ++ ++ F S+ +SA+
Sbjct: 3581 ITDSRRLDSFTDSYELGVSMIKGLRGLFTSSLDAKLVPEHLLRLCLENKKNFTSNYQSAS 3640
Query: 597 RYNFYKDSNAHEIEQMLKVLAPLRQQITSLLNEWEEQNDLQRFLDVIDMLLTLPSDIPLA 656
+YNFYKD + E+ +M+K L PL+Q+I SLL E E+ LQ+ V+ MLL +PS PLA
Sbjct: 3641 KYNFYKDLDGPELGKMVKFLTPLQQRINSLLQEREDHPGLQKLSGVLQMLLAIPSSTPLA 3700
Query: 657 KAFSGLQFLLHKAQVMQENHSKFTFSNQLKSVFDLMSSWHKMELGSWPVLLDEVMDQYEN 716
KA SGLQFLL K +QE K S+ L+ + L SSW K+E WP LLDEV DQYE
Sbjct: 3701 KALSGLQFLLCKVHKLQEEGCKLPISDLLEPIISLASSWQKVEFERWPTLLDEVQDQYEL 3760
Query: 717 NAKKSVLSSSIHYF*SINFPKSNFYFSYESCSLEDFIQTSSFGEFRKRLQLLYAFLGQNH 776
NA+K L F S S SL +FI+TS+ GEFR+RLQLL+ FL Q
Sbjct: 3761 NARKLWLPLFSVLFQKDAVEISEHENESISQSLVEFIETSNVGEFRRRLQLLFCFLLQLS 3820
Query: 777 TSACLKINSSNIVFFLHCWTLQLLSDGAVNILVQYVWILCAVLTNHIDASRKEILTELKD 836
+ L I SS + +D +RK + TELK+
Sbjct: 3821 MGSSLGIYSS--------------------------------VMEQLDLNRKNVETELKE 3848
Query: 837 LVKLCRWEQDKSYSSIENLKKSRQKLKKLIKKHTDILQEPMDKLIRD----------VLH 886
++KLCRWE+ +Y E K++RQK+KKLI+K TD+L+ P+ + D +L
Sbjct: 3849 VLKLCRWERPDNYLYNETTKRTRQKVKKLIQKFTDMLRLPVMLVKPDLTKERAQFLPLLD 3908
Query: 887 KGSISGVSDL--------------------------PLFSDENRLYQE------------ 908
+ G SD+ L R +QE
Sbjct: 3909 PDLMDGASDMRIEVLVSALDAEQLRDRSSWYVVWWNKLKESVGRFHQEMHYKTLLMGAEH 3968
Query: 909 ---------GWKDVWHMIENIYIKAVDSGNIWKEDKNNQRKSRALSDLLNLLKTSGLSQR 959
WK++W + I ++W+ + K RAL +LL LL++SGL +
Sbjct: 3969 QYSSPVYQGDWKNLWSTVARIGETIAGCSDLWRNSDRDVAKKRALFELLKLLESSGLQKH 4028
Query: 960 K------STHKVKIVDSPVHPWK---LMVK*KIKMPLKKAHLRSGRQLLSITSRVLCVCV 1010
K S H ++ P + K L+ K + ++ + RV
Sbjct: 4029 KFENIEMSNHFKGLLYQPAYDPKHLLLLTHTKSNIHPSMGVEDQNKENSLVEWRVANEFY 4088
Query: 1011 FCRKRYASILIKI*L-----------LNRSSSFLSQLVQIQQDQLAAASVFSEKLKCFRE 1059
F K AS+ + + + + R+ SFL+ LV+IQ+ Q +A F+E FR+
Sbjct: 4089 F--KSLASVQLMLNIDRKHSDVTAEQVKRAISFLNHLVEIQRQQRKSAYAFAELFNRFRQ 4146
Query: 1060 FATTMGKLFSFSSPTDNSKSYMCSIVPPNQLATYKCMWQQKQLFDSLCATSNGELLLLRI 1119
++ +L S D + S P NQ A + C+W QKQLFD++ A E LLR
Sbjct: 4147 CVLSLARLLGDSVGADRKDDSVFSF-PQNQHAVFNCLWLQKQLFDNITAMLLEESALLRT 4205
Query: 1120 LENSHLNTCQRTRPSASEMTASIEEFLPVFCKSKESLDCYLIGGSKAVTTIASSHLSVVT 1179
+ ++HL++CQ + S+ + + IE +P+ SK SLD L+ + + T +SS VT
Sbjct: 4206 VGSTHLDSCQAVKTSSRSLLSFIEILIPIAQNSKASLDRLLLDCNGFIITPSSSLKQFVT 4265
Query: 1180 QEMEQLVSENFKVIKDFKDHFLVLQANGMDRSSVKNVLIHHFQEIIDKAKSIEEEFITAK 1239
Q M Q++ +NF + D ++ N ++S ++VL+ F + + K + E
Sbjct: 4266 QHMVQVLRQNFDQLTDLENQISSFCENN-EKSYCRDVLLSQFSPVFKEGKLLAENLNCLL 4324
Query: 1240 NENSNPVDLSEKDHFCGRQCAEPNARFDEALKSTYQHITSVLQSLCS----PSTIPSMIN 1295
N + K+ +E L S + ++ V+ LCS + +N
Sbjct: 4325 NVRDQSTGMEPKERLF----------LEENLASIFANVKDVIGKLCSYKDGSLSQEEEMN 4374
Query: 1296 LGSWELQFVA---NLSLDMLCDDLFKTITFGAKLVNCCDNNISSSSKVGAHFQNLHTLVD 1352
+ +W+ F +L+LD LC L ++ +L+N ++ S+ VG + L +D
Sbjct: 4375 ITTWDGLFKKAENDLNLDNLCKLLSESFGSIEQLLN---SSGVLSAGVGDQLKQLQAFLD 4431
Query: 1353 LLLKFSDELLKNFFAMHKS*QLM*LQIF*FLY--------FQKVLED*QKTRRMMEPLIN 1404
LLL F D LK F A+ K+ L+ + L K ED E
Sbjct: 4432 LLLSFGDCYLKEFLAISKTVSLITHVLASVLADLFTKGFGISKNEEDDDSKVDKSEAAEG 4491
Query: 1405 LKMQVGLAWGKVLD*MMSVIR*LMKISCWEHVNRYVNCLLSMMQKKEEQEESKEVPGNDN 1464
M G+ V D + + L E + + +L + E +E G +
Sbjct: 4492 TGMGDGVGAKDVSDQIEDEDQ-LHGTDKKEEEEKEQDDVLGKNKGIEMSDE---FDGKEY 4547
Query: 1465 TGIEMDQDFQADAVSLSEDSSENEDCDGENEELESEMGPTGPDSEAVGEKIWDQNEDETP 1524
+ E +++ + D S ++ +N D ++ +++ P D E E + ++NE
Sbjct: 4548 SVSEDEEEDKEDEGS-EDEPLDNGIGDVGSDAEKADEKPWNKDEEDEEENMNEKNE---- 4602
Query: 1525 DDTGEKYESGPSVKDGDGSNKELRAKDD--STSDQSGD-DSCDEGDAQNDEAAAQNEFDD 1581
SGPS+ D D ++ELRAKDD T+D+ + ++ D+ + NDE Q++FDD
Sbjct: 4603 --------SGPSIVDKDTRSRELRAKDDGVETADEPEESNTSDKPEEGNDENVEQDDFDD 4654
Query: 1582 EENGDDVNMDKEAAHSDATGLKPDEPDHSSDMEIDLNANEDVDPIEEGDQE-------GH 1634
+N ++ KE A GL PD + D +++++ E+V+ + QE H
Sbjct: 4655 TDNLEEKIQTKEEA---LGGLTPDVDNEQIDDDMEMDKTEEVEKEDANQQEEPCSEDQKH 4711
Query: 1635 DDSAENGNQEDETCPPDEIMEEAHTEVDVSSEKDDLGQEHQENDDMNSMDPKNDTSE--- 1691
+ EN +QE+ P +E ME + S +K++ G + ++ + ++ K SE
Sbjct: 4712 PEEGEN-DQEETQEPSEENMEAEAEDRCGSPQKEEPGNDLEQEPETEPIEGKEVMSEDMM 4770
Query: 1692 SSDVVNPQVSNVDLASQSKSDLQTSGSENIASQSNLSNSHHDFGNPAVTG-GFPSSDMSE 1750
+ N +S V+ SQ+ G+ + A Q NLS + D + PSS +E
Sbjct: 4771 KPNFRNDNISGVESGSQNPHGSNVLGAGSTAPQENLSAT--DVTDELTDSMDLPSSSNTE 4828
Query: 1751 MDINMSDSSNTGGFSKTQPKSHLPQHEHSFSQEKQTNPSRSTGDALDFRKEKINVSGDLP 1810
M++ M++ +N + PK PQ++ S +Q+ + NP R+ GDAL KE++ +S DL
Sbjct: 4829 MNLMMTNMANGETLTDNLPKMEFPQNQSSTAQQTKVNPYRNVGDALKEWKERVRISSDLG 4888
Query: 1811 EDNIEHHGEMDDNNADEYGYVSEFEKGTTQALGPATLEQVDRNIDVDKVDTESRAGED-- 1868
E E EM+D +A EYG+ S+F+ GT+QALGPA EQV+ ++ + + E AG
Sbjct: 4889 EKQ-EAENEMEDPDASEYGFASQFDAGTSQALGPALPEQVNTDMREGESEEEKLAGNQDD 4947
Query: 1869 -ANLQLEKQNSEIDSVSNSSLLPKNEKRDQANMPVMEKS-QDDGSVKPLGSANIDPESHL 1926
+ + ++ N E S N +Q P +++ Q++ + G N S +
Sbjct: 4948 VSPMDIDDLNPENKPAVQSKPSISNSIAEQVQEPDTDRTHQENSPIHNFGDGN----SRM 5003
Query: 1927 EDLISISRSYLGENTHKLSQLSVNDEELGKYHEPCDAPDHVKDNATALWRRYELSTTKLS 1986
+ ++S+ ++LGE L ++ V D + + + PD + NA LWRR EL T K S
Sbjct: 5004 DSMVSVDNTFLGEEACNLDRMQVTDNDSESNQDNQEDPD-ARSNAVVLWRRCELLTAKPS 5062
Query: 1987 QELTEQLRLVLEPTVASKLQGYYKTGKRIHMKKVIQFIASYYRMDKIWLRRTRPNKRDYQ 2046
QEL EQLRL+LEPT+ASKL G Y+TGKRI+MKKVI +IAS+YR DKIWLRRT+PNKRDYQ
Sbjct: 5063 QELAEQLRLILEPTLASKLSGDYRTGKRINMKKVIPYIASHYRKDKIWLRRTKPNKRDYQ 5122
Query: 2047 VVIAVDDSHSMSESCCGDVAVEALVTVCRAVSQLEMGSLAVASFGTKGNINLLHDFDSPF 2106
VVIAVDDS SMSES CGD A+ AL TVCRA+SQLE+GSLAVASFG +G+I +LHDF F
Sbjct: 5123 VVIAVDDSRSMSESGCGDFAIRALATVCRAMSQLELGSLAVASFGKQGSIKMLHDFGQSF 5182
Query: 2107 TAESGVKVSRIYTSLVFFFIDISTVHLLNMLKGSDCSFLTEEQMVSNLTFKQENTIADEP 2166
T ESG+K M+SNLTFKQEN I D+P
Sbjct: 5183 TTESGIK------------------------------------MISNLTFKQENLIEDQP 5206
Query: 2167 VVDLLKFLTNKLDAAVVKARLPSGHNPLQQLVLIIADGRFHEKDNLKRCVREALASNRMV 2226
VV+LL+ + L+ R G NPLQQLVLII DG+FHE++ LKR VR L RMV
Sbjct: 5207 VVNLLRNMNEMLENLASTRRQSYGSNPLQQLVLIIGDGKFHEREKLKRTVRSFLQQKRMV 5266
Query: 2227 AFLLLDNSQESIMDLMEASFEGGKMKFSK--YMDSFPFPYYIVLRNIEALPRTLANLLRQ 2284
+LLLD++++S+ DL + ++G + + K Y+DSFPFPYYIVLR+IEALPRTL ++LRQ
Sbjct: 5267 VYLLLDDAEQSVFDLADYVYDGERRPYKKMNYLDSFPFPYYIVLRDIEALPRTLGDVLRQ 5326
>gb|AAD10657.1| Hypothetical protein [Arabidopsis thaliana] gi|25404666|pir||B96695
hypothetical protein F5A8.4 [imported] - Arabidopsis
thaliana
Length = 5138
Score = 698 bits (1801), Expect = 0.0
Identities = 473/1447 (32%), Positives = 749/1447 (51%), Gaps = 128/1447 (8%)
Query: 24 WNCSHHGTYLPKFLLSAARALFQQIIYAHRKSFDADQYAAIKYNFSSFERNMATEESIHL 83
W S T+ + IIY H+KSF+++ + AIK F + E+ + I
Sbjct: 2860 WQLSDSVTFYADSACENSYRCSDSIIYTHQKSFESETFVAIKSVFHAIEKKQNKMDGIQN 2919
Query: 84 VSTLVGSSRHHRLKNSVNKFIVPLLRELYIQSTTTDFNFNYTIGCAWAHIGALRIHLLLS 143
+ +L+GSS H++LK+ + F+ PL + LY S++ +F N +G AW ++G LR HLL S
Sbjct: 2920 LISLIGSSSHNKLKSVTHSFVGPLAKRLYSDSSSNEFYCN--LGLAWLYLGGLRFHLLNS 2977
Query: 144 YNEVDPVMKYYCKYTQLEETISSLELEIQVRKECGYLSGQFLTVEADKRKAERLEKLQAE 203
+ +DP MK CK +LEE ISSLEL I+VR ECGYLSG + D+ L KL+ E
Sbjct: 2978 LDVIDPAMKITCKLLKLEEKISSLELNIKVRGECGYLSGLLYSGNNDESSEHTLSKLKTE 3037
Query: 204 LRKLQRKIVFRSESWKYKKLMNECDEFLKHIASLEVLVGNVEAEDLQQVIDRTHSWQETA 263
++LQRK++FRS+ KY+ L DEF + LV ++E D QV+++ +WQETA
Sbjct: 3038 HKRLQRKVIFRSDPKKYQDLRRALDEFAGFLTRPISLVNDIEVLDWNQVVEQVFNWQETA 3097
Query: 264 MCFINRLTDEYTAYNDIIQPIQVAVYEMKFGLSLVLSSFLEKEYLRKVGHENINLVTDMI 323
+ FI+R++ +Y+ Y DI QPIQV+VYEMK GLSL +S L + L + + ++ V + I
Sbjct: 3098 ISFIDRMSSDYSEYVDITQPIQVSVYEMKLGLSLFVSGALLGKLLNRFDIDMVDSVMETI 3157
Query: 324 YILMRFPRAASWKFISVEDVGVDLHSSYKLDF-GTDFYLNMGLIERLITLSSGVSADKKV 382
Y LMRFPR +S + + LH S+ + L++GL+ +LI++SS + +K
Sbjct: 3158 YALMRFPRDSSIASTTYTECLPPLHLSHGANSRAKSLGLDVGLLHKLISVSSAEDS-RKA 3216
Query: 383 SAMRCRASIYWNILVQIAYSIANAKIIDRESYMLLHKIFDEFASLWMSMKVYAKSKSDHD 442
S ++ + ++Y N+ ++ +AN ++D S+ LL KI+ E A +WM MK AK+K+D+
Sbjct: 3217 SELQLKVALYKNLHARVLQFVANTGLLDEASFELLDKIYVELARIWMEMKFQAKTKADNL 3276
Query: 443 AQQFKFKPRAFQIESIMELEIPALANSSATEAFSDWKEFSYEEKS---ADNMESSEECEI 499
+KF+ R F+I+S+ME++I AL E+FS+W+E+ ++ + D ++ E
Sbjct: 3277 PGLYKFRSRDFKIDSVMEVDISALGKYFPNESFSEWQEYLADDDTKNVKDMTHIDQDEEN 3336
Query: 500 LDEEWKHLEESILDNVVLIHSQLFGSGDLVQ------APGIFEISDEDRLHSFSESYKLG 553
L+++W ++E LD++ H++LFG DL + G F I+D RL SF++SY+LG
Sbjct: 3337 LEDDWDLIQEH-LDSIYSTHNELFGFCDLSEKTIYSIQSGRFCITDSRRLDSFTDSYELG 3395
Query: 554 INLIKGAHSSNLASLDAKLIPEHLFYLSIDYRRKFHSSSKSANRYNFYKDSNAHEIEQML 613
+++IKG +SLDAKL+PEHL L ++ ++ F S+ +SA++YNFYKD + E+ +M+
Sbjct: 3396 VSMIKGLRGLFTSSLDAKLVPEHLLRLCLENKKNFTSNYQSASKYNFYKDLDGPELGKMV 3455
Query: 614 KVLAPLRQQITSLLNEWEEQNDLQRFLDVIDMLLTLPSDIPLAKAFSGLQFLLHKAQVMQ 673
K L PL+Q+I SLL E E+ LQ+ V+ MLL +PS PLAKA SGLQFLL K +Q
Sbjct: 3456 KFLTPLQQRINSLLQEREDHPGLQKLSGVLQMLLAIPSSTPLAKALSGLQFLLCKVHKLQ 3515
Query: 674 ENHSKFTFSNQLKSVFDLMSSWHKMELGSWPVLLDEVMDQYENNAKKSVLSSSIHYF*SI 733
E K S+ L+ + L SSW K+E WP LLDEV DQYE NA+K + F ++
Sbjct: 3516 EEGCKLPISDLLEPIISLASSWQKVEFERWPTLLDEVQDQYELNARKFCFRRMLWKFQNM 3575
Query: 734 -NFPKSNFYFSYESCSLEDFIQTSSFGEFRKRLQLLYAFLGQNHTSACLKINSSNIVFFL 792
P F + L+ +I SS QL+ L TS +S F+
Sbjct: 3576 KTSPFHKVSFLKDLKGLQHYILKSS--------QLIAPPLFLQLTSNLTVFDSR---FYF 3624
Query: 793 HCWTLQLLSDGAVNILVQYVWILCAVLTNHIDASRKEILTELKDLVKLCRWEQDKSYSSI 852
+ + + NI Y+ L V+ +D +RK + TELK+++KLCRWE+ +Y
Sbjct: 3625 DSDSHKRRVEMCYNIFGFYIQFL-PVVMEQLDLNRKNVETELKEVLKLCRWERPDNYLYN 3683
Query: 853 ENLKKSRQKLKKLIKKHTDILQEPMDKLIRD----------VLHKGSISGVSDL------ 896
E K++RQK+KKLI+K TD+L+ P+ + D +L + G SD+
Sbjct: 3684 ETTKRTRQKVKKLIQKFTDMLRLPVMLVKPDLTKERAQFLPLLDPDLMDGASDMRIEVLV 3743
Query: 897 --------------------PLFSDENRLYQE---------------------GWKDVWH 915
L R +QE WK++W
Sbjct: 3744 SALDAEQLRDRSSWYVVWWNKLKESVGRFHQEMHYKTLLMGAEHQYSSPVYQGDWKNLWS 3803
Query: 916 MIENIYIKAVDSGNIWKEDKNNQRKSRALSDLLNLLKTSGLSQRK------STHKVKIVD 969
+ I ++W+ + K RAL +LL LL++SGL + K S H ++
Sbjct: 3804 TVARIGETIAGCSDLWRNSDRDVAKKRALFELLKLLESSGLQKHKFENIEMSNHFKGLLY 3863
Query: 970 SPVHPWK---LMVK*KIKMPLKKAHLRSGRQLLSITSRVLCVCVFCRKRYASILIKI*L- 1025
P + K L+ K + ++ + RV F K AS+ + + +
Sbjct: 3864 QPAYDPKHLLLLTHTKSNIHPSMGVEDQNKENSLVEWRVANEFYF--KSLASVQLMLNID 3921
Query: 1026 ----------LNRSSSFLSQLVQIQQDQLAAASVFSEKLKCFREFATTMGKLFSFSSPTD 1075
+ R+ SFL+ LV+IQ+ Q +A F+E FR+ ++ +L S D
Sbjct: 3922 RKHSDVTAEQVKRAISFLNHLVEIQRQQRKSAYAFAELFNRFRQCVLSLARLLGDSVGAD 3981
Query: 1076 NSKSYMCSIVPPNQLATYKCMWQQKQLFDSLCATSNGELLLLRILENSHLNTCQRTRPSA 1135
+ S P NQ A + C+W QKQLFD++ A E LLR + ++HL++CQ + S+
Sbjct: 3982 RKDDSVFSF-PQNQHAVFNCLWLQKQLFDNITAMLLEESALLRTVGSTHLDSCQAVKTSS 4040
Query: 1136 SEMTASIEEFLPVFCKSKESLDCYLIGGSKAVTTIASSHLSVVTQEMEQLVSENFKVIKD 1195
+ + IE +P+ SK SLD L+ + + T +SS VTQ M Q++ +NF + D
Sbjct: 4041 RSLLSFIEILIPIAQNSKASLDRLLLDCNGFIITPSSSLKQFVTQHMVQVLRQNFDQLTD 4100
Query: 1196 FKDHFLVLQANGMDRSSVKNVLIHHFQEIIDKAKSIEEEFITAKNENSNPVDLSEKDHFC 1255
++ N ++S ++VL+ F + + K + E N + K+
Sbjct: 4101 LENQISSFCENN-EKSYCRDVLLSQFSPVFKEGKLLAENLNCLLNVRDQSTGMEPKERLF 4159
Query: 1256 GRQCAEPNARFDEALKSTYQHITSVLQSLCS----PSTIPSMINLGSWELQFVA---NLS 1308
+E L S + ++ V+ LCS + +N+ +W+ F +L+
Sbjct: 4160 ----------LEENLASIFANVKDVIGKLCSYKDGSLSQEEEMNITTWDGLFKKAENDLN 4209
Query: 1309 LDMLCDDLFKTITFGAKLVNCCDNNISSSSKVGAHFQNLHTLVDLLLKFSDELLKNFFAM 1368
LD LC L ++ +L+N ++ S+ VG + L +DLLL F D LK F A+
Sbjct: 4210 LDNLCKLLSESFGSIEQLLN---SSGVLSAGVGDQLKQLQAFLDLLLSFGDCYLKEFLAI 4266
Query: 1369 HKS*QLM 1375
K+ L+
Sbjct: 4267 SKTVSLI 4273
Score = 583 bits (1503), Expect = e-164
Identities = 348/856 (40%), Positives = 505/856 (58%), Gaps = 70/856 (8%)
Query: 1450 KEEQEESKEVPGNDNTGIEMDQDFQADAVSLSEDSSENEDCDG-ENEELESEMGPTGPDS 1508
+EE++E +V G N GIEM +F S+SED E+++ +G E+E L++ +G G D+
Sbjct: 4322 EEEEKEQDDVLGK-NKGIEMSDEFDGKEYSVSEDEEEDKEDEGSEDEPLDNGIGDVGSDA 4380
Query: 1509 EAVGEKIWDQNEDETPDDTGEKYESGPSVKDGDGSNKELRAKDD--STSDQSGD-DSCDE 1565
E EK W+++E++ ++ EK ESGPS+ D D ++ELRAKDD T+D+ + ++ D+
Sbjct: 4381 EKADEKPWNKDEEDEEENMNEKNESGPSIVDKDTRSRELRAKDDGVETADEPEESNTSDK 4440
Query: 1566 GDAQNDEAAAQNEFDDEENGDDVNMDKEAAHSDATGLKPDEPDHSSDMEIDLNANEDVDP 1625
+ NDE Q++FDD +N ++ KE A GL PD + D +++++ E+V+
Sbjct: 4441 PEEGNDENVEQDDFDDTDNLEEKIQTKEEA---LGGLTPDVDNEQIDDDMEMDKTEEVEK 4497
Query: 1626 IEEGDQE-------GHDDSAENGNQEDETCPPDEIMEEAHTEVDVSSEKDDLGQEHQEND 1678
+ QE H + EN +QE+ P +E ME + S +K++ G + ++
Sbjct: 4498 EDANQQEEPCSEDQKHPEEGEN-DQEETQEPSEENMEAEAEDRCGSPQKEEPGNDLEQEP 4556
Query: 1679 DMNSMDPKNDTSE---SSDVVNPQVSNVDLASQSKSDLQTSGSENIASQSNLSNSHHDFG 1735
+ ++ K SE + N +S V+ SQ+ G+ + A Q NLS + D
Sbjct: 4557 ETEPIEGKEVMSEDMMKPNFRNDNISGVESGSQNPHGSNVLGAGSTAPQENLSAT--DVT 4614
Query: 1736 NPAVTG-GFPSSDMSEMDINMSDSSNTGGFSKTQPKSHLPQHEHSFSQEKQTNPSRSTGD 1794
+ PSS +EM++ M++ +N + PK PQ++ S +Q+ + NP R+ GD
Sbjct: 4615 DELTDSMDLPSSSNTEMNLMMTNMANGETLTDNLPKMEFPQNQSSTAQQTKVNPYRNVGD 4674
Query: 1795 ALDFRKEKINVSGDLPEDNIEHHGEMDDNNADEYGYVSEFEKGTTQALGPATLEQVDRNI 1854
AL KE++ +S DL E E EM+D +A EYG+ S+F+ GT+QALGPA EQV+ ++
Sbjct: 4675 ALKEWKERVRISSDLGEKQ-EAENEMEDPDASEYGFASQFDAGTSQALGPALPEQVNTDM 4733
Query: 1855 DVDKVDTESRAGED---ANLQLEKQNSEIDSVSNSSLLPKNEKRDQANMPVMEKS-QDDG 1910
+ + E AG + + ++ N E S N +Q P +++ Q++
Sbjct: 4734 REGESEEEKLAGNQDDVSPMDIDDLNPENKPAVQSKPSISNSIAEQVQEPDTDRTHQENS 4793
Query: 1911 SVKPLGSANIDPESHLEDLISISRSYLGENTHKLSQLSVNDEELGKYHEPCDAPDHVKDN 1970
+ G N S ++ ++S+ ++LGE L ++ V D + + + PD + N
Sbjct: 4794 PIHNFGDGN----SRMDSMVSVDNTFLGEEACNLDRMQVTDNDSESNQDNQEDPD-ARSN 4848
Query: 1971 ATALWRRYELSTTKLSQELTEQLRLVLEPTVASKLQGYYKTGKRIHMKKVIQFIASYYRM 2030
A LWRR EL T K SQEL EQLRL+LEPT+ASKL G Y+TGKRI+MKKVI +IAS+YR
Sbjct: 4849 AVVLWRRCELLTAKPSQELAEQLRLILEPTLASKLSGDYRTGKRINMKKVIPYIASHYRK 4908
Query: 2031 DKIWLRRTRPNKRDYQVVIAVDDSHSMSESCCGDVAVEALVTVCRAVSQLEMGSLAVASF 2090
DKIWLRRT+PNKRDYQVVIAVDDS SMSES CGD A+ AL TVCRA+SQLE+GSLAVASF
Sbjct: 4909 DKIWLRRTKPNKRDYQVVIAVDDSRSMSESGCGDFAIRALATVCRAMSQLELGSLAVASF 4968
Query: 2091 GTKGNINLLHDFDSPFTAESGVKVSRIYTSLVFFFIDISTVHLLNMLKGSDCSFLTEEQM 2150
G +G+I +LHDF FT ESG+K M
Sbjct: 4969 GKQGSIKMLHDFGQSFTTESGIK------------------------------------M 4992
Query: 2151 VSNLTFKQENTIADEPVVDLLKFLTNKLDAAVVKARLPSGHNPLQQLVLIIADGRFHEKD 2210
+SNLTFKQEN I D+PVV+LL+ + L+ R G NPLQQLVLII DG+FHE++
Sbjct: 4993 ISNLTFKQENLIEDQPVVNLLRNMNEMLENLASTRRQSYGSNPLQQLVLIIGDGKFHERE 5052
Query: 2211 NLKRCVREALASNRMVAFLLLDNSQESIMDLMEASFEGGKMKFSK--YMDSFPFPYYIVL 2268
LKR VR L RMV +LLLD++++S+ DL + ++G + + K Y+DSFPFPYYIVL
Sbjct: 5053 KLKRTVRSFLQQKRMVVYLLLDDAEQSVFDLADYVYDGERRPYKKMNYLDSFPFPYYIVL 5112
Query: 2269 RNIEALPRTLANLLRQ 2284
R+IEALPRTL ++LRQ
Sbjct: 5113 RDIEALPRTLGDVLRQ 5128
Score = 43.9 bits (102), Expect = 0.066
Identities = 67/361 (18%), Positives = 129/361 (35%), Gaps = 53/361 (14%)
Query: 1575 AQNEFDDEENGDDVNMDKEAAHSDATGLKPDEPDHSSDMEIDLN----ANEDVDPIEEGD 1630
++NE DD+ D + D G K +E + D + N +++ D E
Sbjct: 4292 SKNEEDDDSKVDKSEAAEGTGMGDGVGAKDEEEEKEQDDVLGKNKGIEMSDEFDGKEYSV 4351
Query: 1631 QEGHDDSAENGNQEDETCPPDEIMEEAHTEVDVSSEKDDLGQEHQENDDMNSMDPKNDTS 1690
E ++ E+ EDE P D + + ++ + + EK E E ++MN + +
Sbjct: 4352 SEDEEEDKEDEGSEDE--PLDNGIGDVGSDAEKADEKPWNKDEEDEEENMNEKNESGPSI 4409
Query: 1691 ESSDVVNPQVSNVDLASQSKSDLQTSGSENIASQSNLSNSHHDFGNPAVTGGFPSSDMSE 1750
D + ++ D ++ + + S + + + N N D F +D E
Sbjct: 4410 VDKDTRSRELRAKDDGVETADEPEESNTSDKPEEGNDENVEQD--------DFDDTDNLE 4461
Query: 1751 MDINMSDSSNTGGFSKTQPKSHLPQHEHSFSQEKQTNPSRSTGDALDFRKEKINVSGDLP 1810
I + + GG + P Q + +K + KE N + P
Sbjct: 4462 EKIQTKEEA-LGGLT---PDVDNEQIDDDMEMDKTE----------EVEKEDANQQEE-P 4506
Query: 1811 EDNIEHHGEMDDNNADEYGYVSEFEKGTTQALGPATLEQVDRNIDVDKVD-----TESRA 1865
+ H E +N+ +E T E + N++ + D +
Sbjct: 4507 CSEDQKHPEEGENDQEE------------------TQEPSEENMEAEAEDRCGSPQKEEP 4548
Query: 1866 GEDANLQLEKQNSEIDSVSNSSLLPKNEKRDQANMPVMEKSQDDGSVKPLGSANIDPESH 1925
G D + E + E V + ++ N + D + V SQ+ LG+ + P+ +
Sbjct: 4549 GNDLEQEPETEPIEGKEVMSEDMMKPNFRNDNIS-GVESGSQNPHGSNVLGAGSTAPQEN 4607
Query: 1926 L 1926
L
Sbjct: 4608 L 4608
>gb|AAO53165.1| similar to midasin, a large protein with an N-terminal domain, a
central AAA domain (with similarity to dynein) composed
of 6 tandem AAA protomers, and a C-terminal M-domain
containing MIDAS (Metal Ion Dependent Adhesion Site)
sequence motifs; Mdn1p [Saccharomyces cerevisiae]
[Dictyostelium discoideum]
Length = 5864
Score = 317 bits (812), Expect = 3e-84
Identities = 268/971 (27%), Positives = 441/971 (44%), Gaps = 196/971 (20%)
Query: 1448 QKKEEQEESKEVPGNDNTGIEMDQDFQADAVSLSEDSSENED--CDGENE-ELESEMGP- 1503
+K E+++E KE D G +M DF+ + + +D +++ED D NE E + EMG
Sbjct: 4947 EKDEDEDEEKEEKDEDE-GFDMQDDFEGEMHDIKKDENKDEDKKDDPNNEKENDKEMGDL 5005
Query: 1504 TGPDSEAVGEKIWDQ---NEDETPDDTGEKYESGP----SVKDGDGSNKELRAKDDSTSD 1556
P+ V EK+WD+ ++E D+ G+ E+ + +DG N + + DD D
Sbjct: 5006 EKPEDNVVDEKLWDEQDVQDEEEQDEEGKGDETNSEEMMAKQDGKDDNDDDKKDDDKKDD 5065
Query: 1557 ------------------QSGDDSCDEGDAQN----DEAAAQNEFDDEENGDDV---NMD 1591
+ DD ++G N D A+ +++F EEN DDV +
Sbjct: 5066 KKKKKEENGKPDENEEGEEGKDDEEEDGKDDNKNADDGASDEDDFGQEENEDDVINQEQE 5125
Query: 1592 KEAAHSDATG---------LKPDEPDHSSDMEIDLNANEDV-DPIEEGDQEGHDDSAE-- 1639
KE H D G L+ ++PD + + + +D DP++E D G D S E
Sbjct: 5126 KEENHGDPRGDDQMEIPEDLELEDPDEGKEDDEQQDGGDDFKDPLDEMD--GDDVSKEEE 5183
Query: 1640 -----NGNQEDETCPPDEIMEEAHTEVDVSSEKDDLGQEHQENDDMN--SMDPKNDTSES 1692
+G++++E+ + +E + D ++D +E+Q D N S++P+ D E
Sbjct: 5184 KKKELDGDEKEESDQDGDEEKEDEEKEDGDEDEDKEDKENQPIDPSNVDSINPEGDEPEK 5243
Query: 1693 SDVVNPQVSNVDLASQSKSDLQTSGSE-------NIASQSNLSNSHHDFGNPAVTGGFPS 1745
P+ L + + D SE S+SN+SN+ + + + +
Sbjct: 5244 E---QPEEDQTSLTTNEQQDETPKDSEQPLGVKDKTGSKSNVSNTDEEMKDES------N 5294
Query: 1746 SDMSEMDINMSD---SSNTGGFSKTQPKSHLPQHEHSFSQEKQ----TNPSRSTGDALDF 1798
D ++ D M+ S N G K PQ +KQ NP RS GDA
Sbjct: 5295 QDNADDDSGMTQPTPSENDTGALKNLKSQPPPQSSAQQPPKKQKQVDPNPYRSMGDANKE 5354
Query: 1799 RKEKINVSGDLPEDNIEHHGE-----------MDDNNADEYGYVSEFEK-----GTTQAL 1842
K+++N+ + E+ E E +N +Y ++ + EK T QAL
Sbjct: 5355 WKKRLNLKQEQEEEEEEQSSEPKEKAPKQDPNAKENENQDYEFIKDDEKLDKDEETDQAL 5414
Query: 1843 GPAT----------------LEQVDRNIDVDKVD-------TESRAGEDANLQL-EKQNS 1878
AT EQ + +D+D+ D E +D+ QL E +
Sbjct: 5415 AAATDTQLQDIPQNKAQDDQAEQEEDQMDIDEEDDMDVDHKQEVEHQDDSKQQLDENKKI 5474
Query: 1879 EIDSVSNSSLLPKNEKRDQANMPVMEKSQDDGSVKPLGSANIDPE---SHLEDLISISRS 1935
+ + L + EK + +EK Q DG L N + LE+L ++ +
Sbjct: 5475 SMSKLKQDQLKQQKEKEKEK----LEKDQQDGQDDELDGLNQKEQFTKEQLENLTNLDKE 5530
Query: 1936 YL---------------GENTHKLSQLSVNDEELGKYHEPCD----APDHVKDNATALWR 1976
++ + + + E+L + + + + T LW+
Sbjct: 5531 KAVLDDGDDQEMEQDGDQDDEESVEEKKLTREDLDRMRQELEQYKIENSSNPEIGTELWK 5590
Query: 1977 RYELSTTKLSQELTEQLRLVLEPTVASKLQGYYKTGKRIHMKKVIQFIASYYRMDKIWLR 2036
+YE T LSQ+L EQLRL+LEPT+A+KLQG YK+GKRI+MKKVI +IAS ++ DKIWLR
Sbjct: 5591 KYEQLTNDLSQDLCEQLRLILEPTLATKLQGDYKSGKRINMKKVIPYIASQFKKDKIWLR 5650
Query: 2037 RTRPNKRDYQVVIAVDDSHSMSESCCGDVAVEALVTVCRAVSQLEMGSLAVASFGTKGNI 2096
RT+PNKR YQV++A+DD+ SM+ G A+EA+ + RA+S+LE+G L + FG ++
Sbjct: 5651 RTKPNKRQYQVLLAIDDTESMAAYHSGGFALEAMTMISRAMSRLEVGQLGIVRFGE--DV 5708
Query: 2097 NLLHDFDSPFTAESGVKVSRIYTSLVFFFIDISTVHLLNMLKGSDCSFLTEEQMVSNLTF 2156
L+H FD F+ ++G ++++ F
Sbjct: 5709 QLVHSFDQVFSDQTG------------------------------------PEIITQFKF 5732
Query: 2157 KQENTIADEPVVDLLKFLTNKLDAAVVKARLPSGHNPLQQLVLIIADG-RFHEKDNLKRC 2215
+Q T +++ FL+ L + + SG P QLV I++DG + + K+
Sbjct: 5733 QQTKT-------NMVNFLSKTLQIMDMNKQSSSG-EPAMQLVFIVSDGWSLRDPETTKKY 5784
Query: 2216 VREALASNRMVAFLLLDN--SQESIMDLMEASFEGGKMKFSKYMDSFPFPYYIVLRNIEA 2273
+REA N + F+++DN + SI+D SF GK++ + YM FPF YY++LR++
Sbjct: 5785 LREASIKNVFIVFIVIDNPVNNNSILDFESISFNNGKIQRTNYMSEFPFMYYVILRSLNN 5844
Query: 2274 LPRTLANLLRQ 2284
+P L++ LRQ
Sbjct: 5845 IPSILSDTLRQ 5855
Score = 177 bits (448), Expect = 5e-42
Identities = 211/953 (22%), Positives = 382/953 (39%), Gaps = 152/953 (15%)
Query: 78 EESIHLVSTLVGSSRHHRLKNSVNKFIVPLLRELYIQSTTT----DFNFNYTIGCAWAHI 133
+E I + L+ S + ++P L L + T G +
Sbjct: 3378 DELIENIKELIIQSNDKSFNEKSKQLLLPCLDILLCLDDKVLYKDELKLQSTFGRLQLLL 3437
Query: 134 GALRIHLLLSYNEVDPVMKYYCKYTQLEETISSLELEIQVR----KECGYLSGQFLTVEA 189
R+ + + +DP KY +E L+ EI++R K+ G L ++
Sbjct: 3438 NTFRLIMFVPSGSIDPTQKYDVILQYSKEHSKQLQDEIEIRTIIEKQYTGKDGTSLVIDE 3497
Query: 190 DKRKAERLEKLQAELRKLQRKIVFRSESWKYKKLMNECDEFLKHIASLEVLVGNVEAEDL 249
+K + +++ +L +KI R ++++L + +F H +++E ++ DL
Sbjct: 3498 LVQKKQSIDQ---KLALDSKKITLRPIPSQFEELYRDVSQFSNHFSNIEKIIDLFSKLDL 3554
Query: 250 QQV---------------------------------IDRTHSWQETAMCFINRLTDE-YT 275
QV + WQE A FI + Y+
Sbjct: 3555 SQVKNEFNLEVESEGGDNQQQQENNTSANSSYNQMILSTEQMWQEKANHFIQSCEKKFYS 3614
Query: 276 AYNDIIQPIQVAVYEMKFGLSLVLSSFLEKEYLRKVGHEN--INLVTDMIYILMRFPRAA 333
Y DII PI AVY+MK GL ++ SF +K K+G + ++ L +FPR
Sbjct: 3615 RYRDIIVPIITAVYQMKSGLRMMSVSFKQKVQDNKLGGNQGITKQIQKVLLSLTQFPRIN 3674
Query: 334 SWKFISVEDVGVDLHSSYKLDFGTDFYLNMGLIERLI--TLSSGVSADKKVSAMRCRASI 391
S + + ++ T+ N L+++L ++ + +++ + C +
Sbjct: 3675 S---VDINSKITTTSTTTTATTTTNTTSNNILLDKLTLDSIKDMMKFNQRTNQDNCNGGL 3731
Query: 392 Y---------WNILVQIAYSIANAKIIDRESYMLLHKIFDEFASLWMSMKVYAKSKSDHD 442
+ L QI ++N+ +D ++ + IF F W + + K + +
Sbjct: 3732 QNFKVIGLLLRSSLCQIYSQLSNSNYLDVDNLEAIDSIFRIFVQEWRFQEEEKRKKEELE 3791
Query: 443 AQQFKFKPRAFQIESIMELEIPALANSSAT--EAFSDWKEFSYEEKSADN--------ME 492
Q+FK+K + ++E+ E + S + F D + + E D+ E
Sbjct: 3792 NQEFKYKVQTHKMETKEEKDEKVFLTSFPNFYKDFEDLEVANVVENQIDDDNDEENKDKE 3851
Query: 493 SSEECEILDEEWKHLEESILDNVVL-----IHSQLFGSGDLVQAPGI---FEISDEDRLH 544
++E + E+ +S ++N + IH +F D + P + +SD DR
Sbjct: 3852 NNESNVLTSEDGSMFFKSSINNEEILQLCSIHRDIFKHLDGIPIPKEQQQWTLSDRDRSE 3911
Query: 545 SFSESYKLGINLIK----------------GAH---SSNLASLDAKLIPEHLFYLSIDYR 585
F Y L+K G+H +SNL + P + Y +D +
Sbjct: 3912 LFQLFYSSSYLLMKILNQRSGDMEFDQLSLGSHILSASNLKETLSIRPPSLITYSKLDEK 3971
Query: 586 RKF-------HSSSKSAN----------------RYNFYKDSNAHEIEQMLKVLAPLRQQ 622
+F + SK N YN Y+DSN EI + + L R++
Sbjct: 3972 FRFLKTSSYLYKKSKGINDDDGDNQVVDVIHQKKTYNIYRDSNISEIGIIREPLISFRKR 4031
Query: 623 ITSLLNEWEEQNDLQRFLDVIDMLLTLPSDIPLAKAFSGLQFLLHKAQVMQENHSK-FTF 681
+ LL E+ EQ +L + +ID L+T P+ PLAK +GL+ LL K+ + SK +
Sbjct: 4032 VFELLVEYPEQANLTLMVKLIDRLMTYPATDPLAKILTGLELLLRKSLEWESFASKAVSI 4091
Query: 682 SNQLKSVFDLMSSWHKMELGSWPVLLDEVMDQYENNAKKSVLSSSIHYF*SINFPKSNFY 741
N L + L+ W K+E+ SWP + E A+ L S + IN S+
Sbjct: 4092 QNHLNEISSLIVRWRKLEIESWP----SIFQSQEKEAEVKALKSWFILYDLINDEPSSPE 4147
Query: 742 FSYESCS-----LEDFIQTSSFGEFRKRLQLLYAFLGQNHTSACLKINSSNIVFFLHCWT 796
E+ S L+ ++ +SS G+F R++LL +F Q +++ L S N +
Sbjct: 4148 LEDENLSKNFHTLQQYLYSSSLGDFLTRIELLKSFYKQLNSTIKLIGTSKNTNY------ 4201
Query: 797 LQLLSDGAVNILVQYVWILCAVLTNHIDASRKEILTELKDLVKLCRWEQDKSYSSIENLK 856
Q LSD NI +Y + + + S K I + + ++L RW+ ++ + E LK
Sbjct: 4202 KQKLSDIIYNIF-KYFENFISRFEDRLAKSIKPIEDKALEFIRLSRWDDNRLLTQYERLK 4260
Query: 857 K----SRQKLKKLIKKHTDILQEPMDKLIRD----------VLHKGSISGVSD 895
+ S + L K+ K+ ++L +P+ + VLH G+ + + D
Sbjct: 4261 QHIEVSHRNLAKVTIKYKNVLAQPLHDIFTQIENELDIPPLVLHSGAATILED 4313
Score = 63.2 bits (152), Expect = 1e-07
Identities = 89/450 (19%), Positives = 171/450 (37%), Gaps = 68/450 (15%)
Query: 1481 SEDSSENEDCDGENEELESEMGPTGPDSEAVGEKIWDQNEDETPDDTGEKYESGPSVKDG 1540
++ + E +G E ++ TG E G+K D ++ E ++D
Sbjct: 4893 ADGGDDGEGGEGGRSNFEDDVEGTGM-GEGKGKK-----------DVSDQLEDQGQIEDT 4940
Query: 1541 DGSNKELRAKDDSTSDQSGDDSCDEGDAQNDEAAAQ------NEFDDEENGDDVNMDKEA 1594
+ KE + +D+ + D+ DEG D+ + +E DE+ DD N +KE
Sbjct: 4941 NTQKKEEKDEDEDEEKEEKDE--DEGFDMQDDFEGEMHDIKKDENKDEDKKDDPNNEKEN 4998
Query: 1595 AHSDATGLKPDEPDHSSDMEIDLNANEDVDPIEEGDQEGHDD--------SAENGNQEDE 1646
KP++ + ++ L +DV EE D+EG D + ++G +++
Sbjct: 4999 DKEMGDLEKPED----NVVDEKLWDEQDVQDEEEQDEEGKGDETNSEEMMAKQDGKDDND 5054
Query: 1647 TCPPDEIMEEAHTEVDVSSEKDDLGQEHQENDDMNSMDPKNDTSESSDVVNPQVSNVDLA 1706
D+ ++ + + K D +E +E D D K+D + D A
Sbjct: 5055 DDKKDDDKKDDKKKKKEENGKPDENEEGEEGKDDEEEDGKDDNKNADDG----------A 5104
Query: 1707 SQSKSDLQTSGSENIASQSNLSNSHHDFGNPAVTGGFPSSDMSEMDI----NMSDSSNTG 1762
S Q +++ +Q +H G+P + E++ D G
Sbjct: 5105 SDEDDFGQEENEDDVINQEQEKEENH--GDPRGDDQMEIPEDLELEDPDEGKEDDEQQDG 5162
Query: 1763 GFSKTQPKSHLPQHEHSFSQEKQTNPSRSTGDALDFRKEKINVSGD-LPEDNIEHHGEMD 1821
G P + + S +EK+ GD KE+ + GD ED + G+ D
Sbjct: 5163 GDDFKDPLDEMDGDDVSKEEEKK---KELDGD----EKEESDQDGDEEKEDEEKEDGDED 5215
Query: 1822 DNNADEYGYVSEFEKGTTQALGPATLEQVDRNIDVDKVDTESRAGEDANLQLEKQNSEID 1881
++ D+ Q + P+ ++ + N + D+ + E + +L +Q E
Sbjct: 5216 EDKEDK----------ENQPIDPSNVDSI--NPEGDEPEKEQPEEDQTSLTTNEQQDETP 5263
Query: 1882 SVSNSSLLPKNEKRDQANMPVMEKSQDDGS 1911
S L K++ ++N+ ++ D S
Sbjct: 5264 KDSEQPLGVKDKTGSKSNVSNTDEEMKDES 5293
Score = 49.7 bits (117), Expect = 0.001
Identities = 73/391 (18%), Positives = 142/391 (35%), Gaps = 51/391 (13%)
Query: 1564 DEGDAQNDEAAAQNEFDDEENGDDVN-----------MDKEAAHSDATGLKPDEPDHSSD 1612
D GD ++ F+D+ G + ++ + D K +E D D
Sbjct: 4894 DGGDDGEGGEGGRSNFEDDVEGTGMGEGKGKKDVSDQLEDQGQIEDTNTQKKEEKDEDED 4953
Query: 1613 MEID-LNANEDVDPIEEGDQEGHDDSAENGNQEDETCPPDEIMEEAHTEVDVSSEKDDLG 1671
E + + +E D ++ + E HD + ED+ P+ E D+ +D++
Sbjct: 4954 EEKEEKDEDEGFDMQDDFEGEMHDIKKDENKDEDKKDDPNNEKENDKEMGDLEKPEDNVV 5013
Query: 1672 QEHQENDDMNSMDPKNDTSESSDVVNPQVSNVDLASQSKSDLQTSGSENIASQSNLSNSH 1731
E ++ + + D D N S +A Q D ++ + +
Sbjct: 5014 DEKLWDEQDVQDEEEQDEEGKGDETN---SEEMMAKQDGKDDNDDDKKDDDKKDDKKKKK 5070
Query: 1732 HDFGNPAVTGGFPSSDMSEMDINMSDSSNTGGFSKTQPKSHLPQHEHSF---SQEKQTNP 1788
+ G P E + D+ N + + ++E QEK+ N
Sbjct: 5071 EENGKPDENEEGEEGKDDEEEDGKDDNKNADDGASDEDDFGQEENEDDVINQEQEKEENH 5130
Query: 1789 SRSTGDALDFRKEKINVSGDL--------PEDNIEHHG------EMDDNNADEYGYVSEF 1834
GD +++ + DL ED+ + G +D+ + D+ E
Sbjct: 5131 GDPRGD------DQMEIPEDLELEDPDEGKEDDEQQDGGDDFKDPLDEMDGDDVSKEEEK 5184
Query: 1835 EKGTTQALGPATLEQVDRNIDVDKVDTESRAGEDANLQLEKQNSEIDSVSNSSLLPKNE- 1893
+K L E+ D++ D +K D E G++ + +K+N ID + S+ P+ +
Sbjct: 5185 KK----ELDGDEKEESDQDGDEEKEDEEKEDGDEDEDKEDKENQPIDPSNVDSINPEGDE 5240
Query: 1894 ------KRDQANMPVMEKSQD--DGSVKPLG 1916
+ DQ ++ E+ + S +PLG
Sbjct: 5241 PEKEQPEEDQTSLTTNEQQDETPKDSEQPLG 5271
>gb|EAA58694.1| hypothetical protein AN6310.2 [Aspergillus nidulans FGSC A4]
gi|67540280|ref|XP_663914.1| hypothetical protein
AN6310_2 [Aspergillus nidulans FGSC A4]
gi|49097974|ref|XP_410447.1| hypothetical protein
AN6310.2 [Aspergillus nidulans FGSC A4]
Length = 4917
Score = 303 bits (775), Expect = 6e-80
Identities = 246/886 (27%), Positives = 400/886 (44%), Gaps = 129/886 (14%)
Query: 1444 LSMMQKKEEQEESKEVPGNDNTGIEMDQDF---QADAVSLSEDSSENEDCD-GENEELES 1499
LS + ++E+QE + E + MDQ+ + ED ++E D GE ++++
Sbjct: 4106 LSELAQQEQQEGAGEDIDKSKDAVNMDQEDLKGEEGEHEEEEDGEKDESGDEGEEDDIDE 4165
Query: 1500 EMGPTGP-DSEAVGEKIWDQNEDETPDDTGEKYESGPSVKDGDGSNKELRAKDDSTSDQS 1558
E+G D AV EK+WD DE +T + G S D + E Q
Sbjct: 4166 EVGSVNDLDVSAVDEKMWDGGHDEQQKETENEEGKGASEADQQAAAPE----------QK 4215
Query: 1559 GDDSCDEGDAQNDEAAAQNEFDDEENGDDVNMDKEAAHSDATGLKPDEP---DHSSDMEI 1615
+ +EGD + +EA ++E ++EE DD D T + E D +M++
Sbjct: 4216 EGEKGEEGDKEGEEAEEEDEEEEEEAPDDEGEAVGREDMDVTDPQAPEQETLDLPDEMQL 4275
Query: 1616 DLNANEDVDPIEEGDQEGHDDSAENGNQEDETCPPDEIMEEAHTEVDVSSEKDDLGQEHQ 1675
D + +D + G +G DD + N E PDE +EE D+ E++++ + +
Sbjct: 4276 D-GDEKGMDDEDFGSDDGLDDLPDAPNDEQMDEKPDENIEEEGPG-DLPGEEEEINPDEE 4333
Query: 1676 ---ENDDMNSMDPKNDTSESSDVVNPQVSNVDLASQSKSDLQTSGSENIASQSNLSNSHH 1732
E ++ N+ + +++ ++ P+ + D + D +T+G E S+
Sbjct: 4334 APPEEENANAAEGEDEAQAPAE--EPEETQQDEFLAQRDDNETAGEEVAPSE-------- 4383
Query: 1733 DFGNPAVTGGFPSSDMSEMDINMSDSSNTGGFSKTQPKSHLPQHEHSFSQEKQTNPSRST 1792
AV GG + + S ++ S T P Q + + ++ R
Sbjct: 4384 -----AVNGGLGAEQDQNQEKGASGNAQQQDGS-TDPSVEPKQQTGAAKEGEENERHRDA 4437
Query: 1793 GDALDFRKEKINVS-----GDLPED-----------NIEHHGEMDD--------NNADEY 1828
G D E + GD+ E + + GE D+ +AD
Sbjct: 4438 GGGDDINPEDPQLQAFKKLGDVLEQWHRRQKEIMNASKQEEGETDEPLPQDTEMGDADFE 4497
Query: 1829 GYVSEFEKGTTQALGPATLEQVDRNIDVDKVDTESRAGEDANLQLEKQNSEIDSVSNSSL 1888
+ + TQALG A+ EQ + G +++++ Q D+
Sbjct: 4498 HLADQDDVADTQALGQASEEQAKA--------LDQNRGVESDVKPTDQEMLPDASDEPQA 4549
Query: 1889 LPKNEKRDQANMPVMEKSQDDGSVKPLGSANIDPESHLEDLISISRSYLGENTHKLSQLS 1948
LP+NE D M S +D + A I SH + S +++ E + QL
Sbjct: 4550 LPENELEDAMQMDHNGASTEDQAA----GAFIPGASHAQQNQSDAQAQPAE----IEQLD 4601
Query: 1949 VNDEELGKYHEPCDAPDHV-KDNATALWRRYELSTTKLSQELTEQLRLVLEPTVASKLQG 2007
D L H P +D A LW +YE +T LS LTEQLRL+L PT+A+KL+G
Sbjct: 4602 EVDSHLAAIHLSSTLPPLTPRDEAQRLWSKYESATNDLSLSLTEQLRLILAPTLATKLRG 4661
Query: 2008 YYKTGKRIHMKKVIQFIASYYRMDKIWLRRTRPNKRDYQVVIAVDDSHSMSESCCGDVAV 2067
Y+TGKR+++K++I +IAS Y+ DKIW+RR+ P+KR+YQ+++AVDDS SM ES G +A
Sbjct: 4662 DYRTGKRLNIKRIIPYIASQYKRDKIWMRRSVPSKRNYQIMLAVDDSKSMLESGSGQLAF 4721
Query: 2068 EALVTVCRAVSQLEMGSLAVASFGTKGNINLLHDFDSPFTAESGVKVSRIYTSLVFFFID 2127
E L V +++S LE G L V FG++ ++ + HDF PF++E+GV
Sbjct: 4722 ETLALVAKSLSMLEAGDLCVLGFGSEDHVRVAHDFGKPFSSEAGV--------------- 4766
Query: 2128 ISTVHLLNMLKGSDCSFLTEEQMVSNLTFKQENTIADEPVVDLLKFLTNKLDAAVVKARL 2187
Q+ N +++Q T + + D + A K
Sbjct: 4767 ---------------------QVFQNFSYQQTGTNVRKLIADSIALFRE----ARFKQSP 4801
Query: 2188 PSGHNPLQQLVLIIADGRFHEKDNLKRCVREALASNRMVAFLLLDNSQ-ESIMDLMEASF 2246
G L QL LII+DG + + ++R VR+A M+ F+++D + SI+DL +ASF
Sbjct: 4802 AGGSADLWQLELIISDGICEDHETIRRLVRQAQEERIMIVFIIVDALKGNSILDLTQASF 4861
Query: 2247 EGG--------KMKFSKYMDSFPFPYYIVLRNIEALPRTLANLLRQ 2284
E K+K +Y++ FPFPYY+V+R++ LP LA L+Q
Sbjct: 4862 EPDNESGTGEMKLKMKRYLEGFPFPYYLVVRDVRELPAVLATALKQ 4907
Score = 71.6 bits (174), Expect = 3e-10
Identities = 67/309 (21%), Positives = 140/309 (44%), Gaps = 26/309 (8%)
Query: 591 SSKSANRYNFYKDSNAHEIEQMLKVLAPLRQQITSLLNEWEEQNDLQRFLDVIDMLLTLP 650
++ SA YNFY D N E +++L + ++ + + W + + V +
Sbjct: 3274 TTTSAKNYNFYTDQNPAEAKKLLILTRSIQARFVQIQQAWPDHAVPGDVISVCKEIYQFR 3333
Query: 651 SDIPLAKAFS---GLQFLLHKAQVMQENHSKFTFSNQLKSVFDLMSSWHKMELGSWPVLL 707
P+AK + L L+H+ Q++ +++ ++ + +L+ SW ++EL +W LL
Sbjct: 3334 HTEPVAKFLTKVEKLHSLVHEWQLVASR--EYSAASYYDELTNLIISWRRLELSTWAKLL 3391
Query: 708 DEVMDQYENNAK-------KSVLSSSIHYF*SINFPKSNFYFSYESCSLEDFIQTSSFGE 760
D D+ ++++ + I S S+ + +LE F +++ GE
Sbjct: 3392 DLEKDKCVQGVSSWWFIIFEALIRAPIQIAESGTTDLSD-HVQEVVGTLEQFTHSTTLGE 3450
Query: 761 FRKRLQLLYAFLGQNHTSACLKINSSNIVFFLHCWTLQLLSDGAVNILVQYVWILCAVLT 820
+ +RL+L+ F A L + + +L+ L N L Y AV
Sbjct: 3451 YSERLRLIKDF------RALLSLYVQDYP------SLKQLVFALDNFLQYYAQFEPAVSK 3498
Query: 821 NHIDASRKEILTELKDLVKLCRWEQDKSYSSIENLKKSRQKLKKLIKKHTDILQEPMDKL 880
ID R + ++K+ ++L W+ + E+ K+S KL KL++K+ ++L P++++
Sbjct: 3499 FLID-KRSSLEKDIKEQIQLASWKDTNIVALRESAKRSHVKLFKLVRKYREVLGLPVEQI 3557
Query: 881 IRDVLHKGS 889
+ + +G+
Sbjct: 3558 LSQDMPEGN 3566
Score = 62.4 bits (150), Expect = 2e-07
Identities = 90/435 (20%), Positives = 161/435 (36%), Gaps = 87/435 (20%)
Query: 1519 NEDETPDDTGEKYESGPSVKDGDGSNKELRAKDDSTSDQSGDDSCDEGDAQNDEAAAQNE 1578
+E+ T + K ESG + +G+G+ D S D GD ++ AQ E
Sbjct: 4069 HEESTEEGQSGKLESGTGLGEGEGAE---------------DISKDVGDDEDLSELAQQE 4113
Query: 1579 FDDEENGDDVNMDKEAAHSDATGLKPDEPDH--SSDMEIDLNANE--------------- 1621
E G+D++ K+A + D LK +E +H D E D + +E
Sbjct: 4114 -QQEGAGEDIDKSKDAVNMDQEDLKGEEGEHEEEEDGEKDESGDEGEEDDIDEEVGSVND 4172
Query: 1622 -DVDPIEEGDQEGHDDSAENGNQEDETCPPDEIMEEA----HTEVDVSSEKDDLGQEHQE 1676
DV ++E +G D + + +E E ++A E + E D G+E +E
Sbjct: 4173 LDVSAVDEKMWDGGHDEQQKETENEEGKGASEADQQAAAPEQKEGEKGEEGDKEGEEAEE 4232
Query: 1677 NDDMNSMDPKNDTSES-----SDVVNPQV---SNVDLASQSKSDLQTSGSENIASQSNLS 1728
D+ + +D E+ DV +PQ +DL + + D G ++
Sbjct: 4233 EDEEEEEEAPDDEGEAVGREDMDVTDPQAPEQETLDLPDEMQLDGDEKGMDD-------- 4284
Query: 1729 NSHHDFGNPAVTGGFPSSDMSEMDINMSDSSNTGGFSKTQPKSHLPQHEHSFSQEKQTNP 1788
DFG+ P + E D + + + LP E + +++ P
Sbjct: 4285 ---EDFGSDDGLDDLPDAPNDEQMDEKPDEN-----IEEEGPGDLPGEEEEINPDEEAPP 4336
Query: 1789 SRSTGDALDFRKEKINVSGDLPEDNIEHHGEMDDNNADEYGYVSEFEKGTTQALGPATLE 1848
+A + E P + E ++ DE ++++ + T A E
Sbjct: 4337 EEENANAAEGEDE-----AQAPAE------EPEETQQDE--FLAQRDDNETAGEEVAPSE 4383
Query: 1849 QVDRNIDVDKVDTESRAGEDANLQLEKQNSEIDSVSNSSLLPKNEKRDQANMPVMEKSQD 1908
V+ + ++ D G N Q + D ++ S+ PK + E+ +D
Sbjct: 4384 AVNGGLGAEQ-DQNQEKGASGNAQQQ------DGSTDPSVEPKQQTGAAKEGEENERHRD 4436
Query: 1909 DGSVKPLGSANIDPE 1923
G G +I+PE
Sbjct: 4437 AG-----GGDDINPE 4446
>emb|CAG62826.1| unnamed protein product [Candida glabrata CBS138]
gi|50294870|ref|XP_449846.1| unnamed protein product
[Candida glabrata]
Length = 4880
Score = 297 bits (760), Expect = 3e-78
Identities = 254/893 (28%), Positives = 426/893 (47%), Gaps = 132/893 (14%)
Query: 1451 EEQEESKEVPGNDNTGIEMDQDFQADAVSLSE-DSSENEDCDGENEELESEMGPTGPD-S 1508
++ ++ +E DN ++M+ D + +S+ D+S++ D + + EEL+ E+ D +
Sbjct: 4053 QKDKDDREDDDEDNA-VDMEGDMAGELEDISDQDNSDDSDNESDEEELDEEINDIDDDDA 4111
Query: 1509 EAVGEKIWDQ------------NEDETPDDTGEKYESGPSVK--DGD-GSNKELRAKDDS 1553
AV +K+WD+ N+ E ++ E ++ + + +GD GSNKE +K+++
Sbjct: 4112 NAVDDKMWDEKVDDNLKEKETDNQIENQNNESEDVQAAENEQQENGDEGSNKEPDSKEEN 4171
Query: 1554 TSDQSGDDSCDEGDAQNDEAAAQNEFDDEENGDD---------VNMDKEAAHSDATGLKP 1604
DQ D GD Q + + D+EE+G++ VN +KE DA ++
Sbjct: 4172 NEDQQNDSENQNGDEQ------EQDLDNEESGEEDVGQQEDEVVNDEKEEQMFDAPEIET 4225
Query: 1605 DEPDHSSDMEIDLNANEDVDPIEEGDQ---EGHDDSAENGNQE----DETCPPDEIMEEA 1657
E DM++D D EE D G + +AE E DE D+ ME
Sbjct: 4226 MELPE--DMQLDSEEESKSDNEEEEDDMKDSGFESNAEEMEVEEDILDEKQNKDD-MEVD 4282
Query: 1658 HTEVDVSSEKDDLGQEHQENDDM---NSMDPKNDTS----ESSDVVNPQVSNVDLASQSK 1710
+ E + E+++L ++END+ N+ + ND E + PQ N + +
Sbjct: 4283 NLEEENIEEENNLSDANEENDNQEGENNDEDNNDVDMQDEEQTLQEEPQTENGETGTNI- 4341
Query: 1711 SDLQTSGSENIASQSNLSNSHHDFGNPAVTGGFPSSDMSEMDINMSDSSNTGGFSKTQPK 1770
D G EN ++ ++ + N G + E N+ DS T + Q K
Sbjct: 4342 DDEGAEGIENYLDNNDETSEANAEQNAGAKGAGADTKDDEDQENIGDSGMTNLEHQEQEK 4401
Query: 1771 SHLPQHEHSFSQEKQTNPSRSTGDAL-DFRKEKINVSGDLPEDNIEHHGEMDDNNADEYG 1829
++ + S+EK + GD+L ++ + ++ ++N E+ + + DE+
Sbjct: 4402 DS--ENHNDSSREKANEVLKELGDSLKEYHNRRQEINNPSNDENKENENKANQR-PDEFE 4458
Query: 1830 YVSEFEKGT-TQALGPATLEQVDRNIDVDKVDTESRAGEDANLQLEKQNSEIDSVSNSSL 1888
++ T TQALG A E+ + K+D + +D + + EK +S+ID+ ++L
Sbjct: 4459 HLDGANTETDTQALGGANQEEAN------KIDDDLAINDDLDEE-EKIDSDIDTDDAANL 4511
Query: 1889 LPKNEKRDQANMPVMEKSQDDGSVKPLGSANIDPESHLEDLISISRSYLGENT------- 1941
NE +++ + Q D K G+ S ++DL SI + EN
Sbjct: 4512 ESHNEIKEELEEDLNTDIQKDTDSKSQGAF----ASTMKDL-SIEDKEIYENDGLFKRED 4566
Query: 1942 --HKLSQLSVNDEELGKYHEPCDAPDHVKDNATALWRRYELSTTKLSQELTEQLRLVLEP 1999
++L QL ++ D P + LWR+ E+ T +LS L EQLRL+LEP
Sbjct: 4567 YENELDQLMDEIDKETNLKAEIDKPQRDLTESRELWRKSEIETVELSARLGEQLRLILEP 4626
Query: 2000 TVASKLQGYYKTGKRIHMKKVIQFIASYYRMDKIWLRRTRPNKRDYQVVIAVDDSHSMSE 2059
T+A+KL+G YKTGKR++MK++I +IAS YR DKIWLRRT+P+KR YQ+++A+D+S SMSE
Sbjct: 4627 TLATKLRGDYKTGKRLNMKRIIPYIASQYRKDKIWLRRTKPSKRQYQIMLALDNSKSMSE 4686
Query: 2060 SCCGDVAVEALVTVCRAVSQLEMGSLAVASFGTKGNINLLHDFDSPFTAESGVKVSRIYT 2119
S +A +L V + +SQLE G L++ FG +H FD F+ +SG KV + +
Sbjct: 4687 SKSAQLAFNSLCLVSKTLSQLESGGLSIVRFGE--YTKEVHSFDQNFSNDSGSKVFQWF- 4743
Query: 2120 SLVFFFIDISTVHLLNMLKGSDCSFLTEEQMVSNLTFKQENTIADEPVVDLLKFLTNKLD 2179
F+++ T V + +K
Sbjct: 4744 -----------------------------------NFQEDKTDVKRLVGESIKIFE---- 4764
Query: 2180 AAVVKARLPSGHNPLQQLVLIIADGRFHEKDNLKRCVREALASNRMVAFLLLDN---SQE 2236
+AR S N QL ++I+DG + D ++R VR A M+ F+++DN S E
Sbjct: 4765 ----RARAYS-DNDQWQLEIVISDGLCEDHDTVERLVRRARDKKIMLVFVIIDNLGQSNE 4819
Query: 2237 SIMDLMEASFEGG-----KMKFSKYMDSFPFPYYIVLRNIEALPRTLANLLRQ 2284
SIMD+ + + ++K +KY+D+FPF +Y+V+ +I LP LA +LRQ
Sbjct: 4820 SIMDMSQVKYVPDSSGNLQLKITKYLDTFPFEFYVVVHDIVELPEMLALILRQ 4872
Score = 88.2 bits (217), Expect = 3e-15
Identities = 143/769 (18%), Positives = 299/769 (38%), Gaps = 121/769 (15%)
Query: 123 NYTIGCAWAHIGALRIHLLLSYNEVDPVMKYYCKYTQLEETISSLELEIQVRKECGYLSG 182
++ + W + G I L DP ++ Y +Y L+ E + G+
Sbjct: 2848 SFALASCWIYFGITLIELFCPDTAFDPAIENYVQYDLFRSHRDFLQAE-----KSGWAKF 2902
Query: 183 QFLTVEADKRKAERLEKLQAELRKLQRKIVFRSESWKYKKLMNECDEFLKHIASLEVLVG 242
+ +T E L + E ++ +V+R+ L +E + FL S + +
Sbjct: 2903 RMVTSGVTPIYNELLAQSIEEPSAPEKPLVYRTNE-AVDDLFDEWNAFLLSSLSQDHIND 2961
Query: 243 NVEAEDLQQVID-RTHSWQETAMCFINRLTDEYTAYNDIIQPIQVAVYEMKFGLSLVLSS 301
V+A L+ I R S Q + F+ R+ + ++D+ ++ +KFG ++
Sbjct: 2962 LVQAGKLKHSISSRLDSLQVNSSKFVERVKSGFKMFSDLNDIFAGYIFAIKFGFDIMKQK 3021
Query: 302 FLEKEYLRKVGHENINLVTDMIYILMRFPRAASWKFISVEDVGVDLHSSYKLDFGTDFYL 361
L ++N++ T ++ + ++V + V H +
Sbjct: 3022 LL---------NDNLHQGTTRLWAVN--------PLLTVSEYSVKQH-----------FK 3053
Query: 362 NMGLIERLITLSSGVSADKKVSAMRCRASIYWNILVQIAYSIANAKIIDRESYMLLHKIF 421
NM ++ + + ++ AD+ + + + Y + +++D + H+
Sbjct: 3054 NMFVMLQRAS-ANNYDADRTLL----------HFVRLFRYFKQSDELLD-----IFHESL 3097
Query: 422 DEFASLWMSMKVYAKSKSDHDAQQFKFKPRAFQIESIMELEIPALANSSATEAFSDWKEF 481
+ W K+ ++ K + A+ FK+ + E E F D+
Sbjct: 3098 HTLYARWSMRKMQSEKKQEEQAKTFKYTDESDDFEREFR------------EMFPDYD-- 3143
Query: 482 SYEEKSADNMESSEECEILDEEWKHLEESILDNVVLIHSQLFGSGDLVQAPGIFEISDED 541
D + SE+ + DEE L + + + LF S + + + I++
Sbjct: 3144 -------DELNLSEDIKSQDEETVDLYHQL----TIEYMNLFSSDEQLSLNDV--ITEGT 3190
Query: 542 RLHSFSESYKLGINLIKGAHSSNLASLDAKLIPEHLFYLSIDYRRKFHSSSKSANR-YNF 600
++ S S L L G + PE L ++ +K + K+ N+ ++
Sbjct: 3191 KISSLDNS--LSAQLTSGI-----------VTPETLLSVANILAQKINGFDKTENKSFSI 3237
Query: 601 YKDSNAHEIEQMLKVLAPLRQQITSLLNEWEEQNDLQRFLDVIDMLLTLPSDIPLAKAFS 660
+KD + E ++ + + L ++ LLN+W E LQ L+ D +A+
Sbjct: 3238 FKDFSIPESKKAARSILTLLGKVNELLNQWPENATLQDLFRTCHEFLSFTLDTTIARQLQ 3297
Query: 661 GLQFLLHKAQVMQENHSKFTFS--NQLKSVFDLMSSWHKMELGSWPVLLDEVMDQYENNA 718
L+ ++ E ++ T S + + + + + SW +MEL SW E++ + A
Sbjct: 3298 KLE-QIYTILTEWEKYASSTVSLNDYITEIVNTLVSWRRMELRSW----SELLLNEDKQA 3352
Query: 719 KKSVLSSSIHYF*SINFP-KSNFYFSYESC-----SLEDFIQTSSFGEFRKRLQLLYAFL 772
++S+ + + +I P +SN E +L F S+ GE+ R+ L+ +F
Sbjct: 3353 QRSISKWWFYLYETIILPTESNMDGENEKQYKLLQALNVFFSESTIGEYDHRINLVISFK 3412
Query: 773 GQNHTSACLKINSSNIVFFLHCWTLQLLSDGAVNILVQYVWILCAVLTNHIDASRKEILT 832
S K + N + NI++ Y V + I +RK +
Sbjct: 3413 EHLLNSFPNKEQTINAL---------------TNIILYYKQFQEKV-QDVIKTTRKTLDK 3456
Query: 833 ELKDLVKLCRWEQDKSYSSIENLKKSRQKLKKLIKKHTDILQEPMDKLI 881
++KD++ L W+ + ++ KKS L K+++K+ +++ + LI
Sbjct: 3457 DMKDIILLASWKDVNIDALKQSSKKSHNNLYKIVRKYRNVISGKVTDLI 3505
Score = 68.2 bits (165), Expect = 3e-09
Identities = 89/443 (20%), Positives = 158/443 (35%), Gaps = 50/443 (11%)
Query: 1540 GDGSNKELRAKDDSTSDQSGDDSCDEGDAQNDEAAAQNEFDDEENGDDVNMDKEAAHSDA 1599
GDG E ++ D + +D+ Q D+ E DDE+N D+ D D
Sbjct: 4024 GDGEGAENKSNDIDQDEDLTEDAQTSNQDQKDK--DDREDDDEDNAVDMEGDMAGELEDI 4081
Query: 1600 TGL-KPDEPDHSSDMEIDLNANEDVDPIEEGDQEGHDD------------------SAEN 1640
+ D+ D+ SD E +E+++ I++ D DD EN
Sbjct: 4082 SDQDNSDDSDNESDEE---ELDEEINDIDDDDANAVDDKMWDEKVDDNLKEKETDNQIEN 4138
Query: 1641 GNQEDETCPPDEIMEEAHTEVDVSSEKDDLGQEHQENDDMNSMDPKNDTSESSDVVNPQV 1700
N E E E E D S K+ +E D N + +N + D+ N +
Sbjct: 4139 QNNESEDVQAAE--NEQQENGDEGSNKEPDSKEENNEDQQNDSENQNGDEQEQDLDNEES 4196
Query: 1701 SNVDLASQSKSDLQTSGSENIASQSNLSNSHHDFGNPAVTGGFPSSDMSEMDINMSDSSN 1760
D+ Q + E + + + SD E + +M DS
Sbjct: 4197 GEEDVGQQEDEVVNDEKEEQMFDAPEIETMELPEDMQLDSEEESKSDNEEEEDDMKDS-- 4254
Query: 1761 TGGFSKTQPKSHLPQHEHSFSQEKQTNPSRSTGDALDFRKEKINVSGDLPEDNIEHHGEM 1820
GF + + E EKQ + + E+ N D E+N GE
Sbjct: 4255 --GFESNAEEMEV---EEDILDEKQNKDDMEVDNLEEENIEEENNLSDANEENDNQEGEN 4309
Query: 1821 DDNNADEYGYVSE---------FEKGTT----QALGPATLEQ-VDRNIDVDKVDTESRA- 1865
+D + ++ E E G T G +E +D N + + + E A
Sbjct: 4310 NDEDNNDVDMQDEEQTLQEEPQTENGETGTNIDDEGAEGIENYLDNNDETSEANAEQNAG 4369
Query: 1866 --GEDANLQLEKQNSEIDSVSNSSLLPKNEKRDQANMPVMEKSQDDGSVKPLGSANIDPE 1923
G A+ + ++ I ++L + +++D N + + + +K LG + +
Sbjct: 4370 AKGAGADTKDDEDQENIGDSGMTNLEHQEQEKDSENHNDSSREKANEVLKELGDSLKEYH 4429
Query: 1924 SHLEDLISISRSYLGENTHKLSQ 1946
+ +++ + S EN +K +Q
Sbjct: 4430 NRRQEINNPSNDENKENENKANQ 4452
Score = 53.9 bits (128), Expect = 6e-05
Identities = 74/349 (21%), Positives = 138/349 (39%), Gaps = 49/349 (14%)
Query: 1626 IEEGDQEGHDDSAENGNQEDETCPPDEIMEEAHTEVDVSSEKDDLGQEHQENDDMNSMDP 1685
+ EG G + AEN + + + +++ E+A T +KDD + D+ N++D
Sbjct: 4017 LHEGTGLGDGEGAENKSNDIDQ--DEDLTEDAQTSNQDQKDKDDREDD----DEDNAVDM 4070
Query: 1686 KNDTSESSDVVNPQVSNVDLASQSKSDLQTSGSENIASQSNLSNSHHDFGNPAVTGGFPS 1745
+ D + + D++ Q SD S+N + + L +D +
Sbjct: 4071 EGDMAGELE---------DISDQDNSD----DSDNESDEEELDEEINDIDD--------- 4108
Query: 1746 SDMSEMDINMSDSSNTGGFSKTQPKSHLP-QHEHSFSQEKQTNPSRSTGDALDFRKEKIN 1804
D + +D M D + + + + Q+ S + N + GD E N
Sbjct: 4109 DDANAVDDKMWDEKVDDNLKEKETDNQIENQNNESEDVQAAENEQQENGD------EGSN 4162
Query: 1805 VSGDLPEDNIE-HHGEMDDNNADEYGYVSEFEKGTTQALGPATLEQV-----DRNIDVDK 1858
D E+N E + ++ N DE + E+ + +G E V ++ D +
Sbjct: 4163 KEPDSKEENNEDQQNDSENQNGDEQEQDLDNEESGEEDVGQQEDEVVNDEKEEQMFDAPE 4222
Query: 1859 VDTESRAGEDANLQLEKQ----NSEIDSVSNSSLLPKNEKRDQANMPVMEKSQ--DDGSV 1912
++T ED L E++ N E + S N + + ++++ Q DD V
Sbjct: 4223 IET-MELPEDMQLDSEEESKSDNEEEEDDMKDSGFESNAEEMEVEEDILDEKQNKDDMEV 4281
Query: 1913 KPLGSANIDPESHLEDLISISRSYLGENTHK-LSQLSVNDEELGKYHEP 1960
L NI+ E++L D + + GEN + + + + DEE EP
Sbjct: 4282 DNLEEENIEEENNLSDANEENDNQEGENNDEDNNDVDMQDEEQTLQEEP 4330
Score = 50.1 bits (118), Expect = 0.001
Identities = 69/402 (17%), Positives = 151/402 (37%), Gaps = 59/402 (14%)
Query: 1555 SDQSGDDSCDEGDAQNDEAAAQNEFDDEENGDDVNMDKEAAHSDATGLKPDEPDHSSDME 1614
S+++ D++ EG D A+N+ +D + +D+ D + ++ D
Sbjct: 4009 SEETYDENLHEGTGLGDGEGAENKSNDIDQDEDLTEDAQTSNQDQ--------------- 4053
Query: 1615 IDLNANEDVDPIEEGDQEGHDDSAENGNQEDETCPPDEIMEEAHTEVDVSSEKDDLGQEH 1674
++ D DD + E + E + + D +E D+ +
Sbjct: 4054 ------------KDKDDREDDDEDNAVDMEGDMAGELEDISDQDNSDDSDNESDEEELDE 4101
Query: 1675 Q----ENDDMNSMDPKNDTSESSDVVNPQVSNVDLASQSKSDLQTSGSENIASQSNLSNS 1730
+ ++DD N++D K + D + + ++ + +Q+ +EN ++ S
Sbjct: 4102 EINDIDDDDANAVDDKMWDEKVDDNLKEKETDNQIENQNNESEDVQAAENEQQENGDEGS 4161
Query: 1731 HHDFGNPAVTGGFPSSDMSEMDINMSDSSNTGGFSKTQPKSHLPQHEHSFSQEKQTNPSR 1790
+ + P S + +DS N G + Q + E Q++ +
Sbjct: 4162 NKE----------PDSKEENNEDQQNDSENQNGDEQEQDLDNEESGEEDVGQQEDEVVND 4211
Query: 1791 STGDALDFRKEKINVSGDLPE------------DNIEHHGEMDDNNADEYGYVSEFEKGT 1838
+ + F +I +LPE DN E +M D+ + E E+
Sbjct: 4212 EKEEQM-FDAPEIETM-ELPEDMQLDSEEESKSDNEEEEDDMKDSGFESNAEEMEVEEDI 4269
Query: 1839 TQALGPATLEQVDRNIDVDKVDTESRAGEDANLQLEKQNSEIDSVSNSSLLPKNEKRDQA 1898
+VD N++ + ++ E+ DAN + + Q E + N+ + ++E++
Sbjct: 4270 LDEKQNKDDMEVD-NLEEENIEEENNL-SDANEENDNQEGENNDEDNNDVDMQDEEQTLQ 4327
Query: 1899 NMPVMEKSQDDGSVKPLGSANIDPESHLEDLISISRSYLGEN 1940
P E + ++ G+ I E++L++ S + +N
Sbjct: 4328 EEPQTENGETGTNIDDEGAEGI--ENYLDNNDETSEANAEQN 4367
>emb|CAI20706.1| novel protein similar to human MDN1, midasin homolog (yeast) (MDN1)
[Danio rerio]
Length = 2197
Score = 294 bits (752), Expect = 3e-77
Identities = 262/927 (28%), Positives = 441/927 (47%), Gaps = 160/927 (17%)
Query: 1450 KEEQEESKEVPGNDNTGIEMDQDFQADAVSLS--EDSSENEDCDGENEELESEMGPTGP- 1506
K+E+E+ K+ ++ IEM +DF + E + ED D E+EEL+ +MG G
Sbjct: 1329 KDEEEQDKQDIKEEDNAIEMSEDFDGKMHDGTDREPGEDEEDSDKEDEELDKKMGDLGDG 1388
Query: 1507 DSEAVGEKIW--DQNEDETPDDTGEKYESGPSVKDGDGSNKELRAKDDST-SDQSGDDSC 1563
++ + E++W D ++++ DD+ ++ ESGP + G+ EL AKDD+T + +S D
Sbjct: 1389 QTDTLDERMWGDDDDDEDNNDDSDKEEESGPGMDQGES---ELVAKDDNTDAGESNKDKN 1445
Query: 1564 DEGDAQNDEAAAQN--------EFDDEENG------------------DDVNMDKEAAHS 1597
+ D DE + EFD+ E +++N+D++
Sbjct: 1446 QDKDLPKDEEEKEKIHEQVDEREFDENEVDPYHGKQEKKAEPEAMELPEELNLDEDGKDE 1505
Query: 1598 DATGLKPDEPDHSSD--MEIDLNANEDVDPIEEGDQEGHDDSAENGNQEDETCPPD--EI 1653
+ + P D ME+D ED EEG E D+ + G QE+E D E
Sbjct: 1506 EGEEANEENPFDIDDKLMEVDEKTGEDKGEPEEGGDEMTDEQQQEG-QEEEHGEEDNTEE 1564
Query: 1654 MEEAHTEVDVSSEKDDLGQEHQENDDMNS-------------------MDPKNDTSESSD 1694
EEA D E D+ G+ +E+D+ +PK + D
Sbjct: 1565 KEEAEKSEDQDPEMDERGENEEEDDNKEKNKGQEEGREEDKSIPADQGQEPKKEEDGDED 1624
Query: 1695 VVNPQVSNVDLASQSK--SDLQTSGSENIASQS--NLSNSHHDFGNPAVTGGFPSSDMSE 1750
P +D A + + SD QT G EN+ S + L+ + + G ++D S+
Sbjct: 1625 DEAP----LDSAERKEHASDGQT-GEENVQSDTAVELAGAASEKDQAKEEDGSGAADASQ 1679
Query: 1751 MDINMSDSSNTGGFSKTQPKSHLPQHEHSFSQEK-QTNPSRSTGDALDFRKEKINVSGDL 1809
S+ ++ ++ + ++ SF ++ Q + RS GD + +++ D
Sbjct: 1680 -----SEGHDSKLMARMSSQKQRQKNTQSFKRKPGQADNERSMGDYNERVNKRLRTV-DK 1733
Query: 1810 PEDNIEHHGEMD-DNNADEYGYVSEF-EKGTTQALGPATLEQVD-RNIDVDKVDTESRAG 1866
E + + D +D Y ++ + E+ Q A+ EQ + ++ D E
Sbjct: 1734 TEQKTQDQTQPDTQQESDLYEHIKQGDERYDAQTYDVASKEQQKPTGVKQEEEDEE---- 1789
Query: 1867 EDANLQLEKQNSEIDSVSNSSLLPKNEKRDQANMPVMEKSQDDGSVKPLGSANIDPESHL 1926
+D +++E++ ++ +V L P+ ++A+ +K D G ++ A + L
Sbjct: 1790 DDIAMEVEEEK-DLQAVEAQELKPEKLNDNKAS----QKGLDCGDLEAQKQAIEEEMEKL 1844
Query: 1927 EDLISISRSYLGENT-----HKLSQLSV--------NDEELGKYHE-------PCDAPDH 1966
E SI+ + E + H + +L + N EEL + E H
Sbjct: 1845 ETQRSINEEEMKERSDESTIHTVPELLMETQKATLMNPEELRREMELQLEAWQRQTLGSH 1904
Query: 1967 VKDNATA-LWRRYELSTTKLSQELTEQLRLVLEPTVASKLQGYYKTGKRIHMKKVIQFIA 2025
+++A A LW +Y+ T+ LSQ+L EQLRLVLEPT A+KL+G ++TGKR++M+KVI +IA
Sbjct: 1905 EEESAAAALWHQYQTLTSPLSQQLCEQLRLVLEPTQAAKLRGDFRTGKRLNMRKVIPYIA 1964
Query: 2026 SYYRMDKIWLRRTRPNKRDYQVVIAVDDSHSMSESCCGDVAVEALVTVCRAVSQLEMGSL 2085
S +R DKIWLRRT+P+KR+YQ+ +AVDDS SM ++ +A EA+ + A++ LE+G +
Sbjct: 1965 SQFRKDKIWLRRTKPSKRNYQICLAVDDSSSMVDNHTKQLAFEAVSVIVNALTLLEVGQV 2024
Query: 2086 AVASFGTKGNINLLHDFDSPFTAESGVKVSRIYTSLVFFFIDISTVHLLNMLKGSDCSFL 2145
+V SFG + LLH F F ++G K+ R+
Sbjct: 2025 SVCSFGE--TVQLLHPFHQQFNDQTGAKILRL---------------------------- 2054
Query: 2146 TEEQMVSNLTFKQENTIADEPVVDLLKFLTNKLDAAVVKARLPSGHN-PLQQLVLIIADG 2204
F+Q+ T + L+ TN AA K ++P N QL+LI++DG
Sbjct: 2055 --------CQFQQKKT----RIAQFLETSTNMFMAA--KQQIPGATNTETSQLLLIVSDG 2100
Query: 2205 R---FHEKDNLKRCVREALASNRMVAFLLLD--NSQESIMDLMEASFEG-GKM-KFSKYM 2257
R K+ + V+ A ++N V F++LD NS++SI+D+ F+G G++ + YM
Sbjct: 2101 RGLFLEGKERVATAVQAARSANVFVIFVVLDNPNSRDSILDIKVPIFKGPGELPEIRSYM 2160
Query: 2258 DSFPFPYYIVLRNIEALPRTLANLLRQ 2284
+ FPFP+Y++LRN+ LP TL++ LRQ
Sbjct: 2161 EEFPFPFYVILRNVNGLPETLSDALRQ 2187
Score = 142 bits (358), Expect = 1e-31
Identities = 167/758 (22%), Positives = 300/758 (39%), Gaps = 101/758 (13%)
Query: 196 RLEKLQAELRKLQRKIVFRSESWKYKKLMNECDEFL-------------KHIASLEVLVG 242
R+++++ ++ +L RK +R +Y +L E +L H+ G
Sbjct: 5 RMQQVKEQICELSRKQAYRPPEPQYGRLYQELQHYLCSIGQPAAVGDLLSHLLKALQAPG 64
Query: 243 NVEAEDLQQVIDRTHSWQETAMCFINRLTDEYTAYNDIIQPIQVAVYEMKFGLSLVLSSF 302
+Q ++ WQ + F RL +E+ Y D++ P++ A+ +++ G+ L+ S
Sbjct: 65 PKSKLGVQGLLKEEAVWQASQHRFSQRLLEEFPLYPDVVVPLRAAILQVQHGMRLLAS-- 122
Query: 303 LEKEYLRKVGHENINLVTDMIYILMRFPRAASWKFISVEDVGVDLHSSYKLDFGTDFYLN 362
+ + ++LV+ M+ FP + ++ D+ +
Sbjct: 123 -QVSFSTTAQPGLVHLVSTML----TFPCPVASSDLAC----------------ADYLCS 161
Query: 363 MGLIERLITLSSGVSADKKVSAMRCRASIYWNILVQIAYSIANAKIIDRESYMLLHKIFD 422
+ L TL + A + + A + N L+ I +A + E+ L +
Sbjct: 162 RECLRTLKTLGKQLPATEVSRVIPDHAVLLLNALLYIQSHTLSAGQLSAEAQKLFRHVCQ 221
Query: 423 EFASLWMSMKVYAKSKSDHDAQQFKFKPRAFQIESIMELEIPALANSSATEAFSDWKEFS 482
+ W + A+ K +A ++ + R + + S D+ + +
Sbjct: 222 AIVNEWDEQEKRAREKEQMEASLYRSRSRLHGTGLTEDQQEEREFRRSFPSYHKDFADIT 281
Query: 483 YEEKSADN---MESSEECEILDE--EWKHLEESILDNVVLIHSQLFGSGDLVQAPGIFEI 537
E S D +E ++ ++ E E L S + VV +H +L L A ++
Sbjct: 282 -SEPSLDQPIIIEDDDDADMKAESSETSSLLISNMSRVVQVHQRLC----LSFARSLWYH 336
Query: 538 SD------EDRLHSFSESYKLGINLIKGAHSSNLASLDAKLIPEHLFYLSIDYRRKFHSS 591
S+ +D + + SY++ LI + +++KL+ L LS + S
Sbjct: 337 SEPPTNHAKDHISALVSSYQITAPLIARFYHLMDCEVNSKLMGSQLL-LSTLLQNTVSGS 395
Query: 592 SKSANR-------YNFYKDSNAHEIEQMLKVLAPLRQQITSLLNEWEEQNDLQRFLDVID 644
SA Y+FY++ N + L L L + + LN+W E L + + VI+
Sbjct: 396 GGSAGLILQNDGPYDFYREPNMSQARLCLPALEQLSKAVRQRLNDWPEHPALVQIIMVIE 455
Query: 645 MLLTLPSDIPLAKAFSGLQFLLHKAQVMQENHSK-FTFSNQLKSVFDLMSSWHKMELGSW 703
+L PLAK +GL+ LL KAQ + N S+ + N+L+ V L+ W K+EL W
Sbjct: 456 RILAFSLSSPLAKFLNGLEILLSKAQDWENNASRAVSLRNELEVVTQLIIQWRKLELNCW 515
Query: 704 PVLLDEVMDQYENNAKKSVLS--SSIHYF*SINFPKS-------NFYFSYESCSLEDFIQ 754
LD + ++ N+ K LS I + S N S S SL+ FI+
Sbjct: 516 SSSLDNALKRHAENSTKHWLSIYQLIEKYLQEQKTNSRHDDGVENLSLSSVSSSLQAFIE 575
Query: 755 TSSFGEFRKRLQLLYAFLGQNHTSACLKINSSNIVFFLHCWTLQLLSDGAVNILVQYVWI 814
S+ GEF RL +L F HC L + L +W
Sbjct: 576 GSTLGEFSVRLSMLLGF---------------------HCHILLAPKQEGHDSLCSLLWN 614
Query: 815 L-------CAVLTNHIDASRKEILTELKDLVKLCRWEQDKSYSSIENLKKSRQKLKKLIK 867
L + I R + ELKD VK+ +W +S +++K+ + L K +K
Sbjct: 615 LYKYYSQFSPSIQTKITHLRSPLEKELKDFVKISKWNDVSFWSIKHSVEKTHRTLFKFVK 674
Query: 868 KHTDILQEPMDKLIRDVLHKGSISGVSDLPLFSDENRL 905
K L+EP + + +GS S + D+ +E L
Sbjct: 675 KFEAALKEPCAPCL---VEQGSSSSMDDVDSQPEETPL 709
Score = 57.8 bits (138), Expect = 4e-06
Identities = 87/450 (19%), Positives = 175/450 (38%), Gaps = 43/450 (9%)
Query: 1531 YESGPSVKDGDGSNKELRAKDDSTSDQSGDDSCDEGDAQNDEAAAQNEFDDEENGDDVNM 1590
YE G + +G+G D ++ +D+ EG +++E + + +E+N +++
Sbjct: 1295 YEGG-GIGEGEGVKD---VSDKIENEDQVEDTFQEGKDKDEEEQDKQDIKEEDNAIEMSE 1350
Query: 1591 DKEAAHSDATGLKPDEPDHSSDM---EIDLNANE----DVDPIEE---GDQEGHDDSAEN 1640
D + D T +P E + SD E+D + D ++E GD + +D+ ++
Sbjct: 1351 DFDGKMHDGTDREPGEDEEDSDKEDEELDKKMGDLGDGQTDTLDERMWGDDDDDEDNNDD 1410
Query: 1641 GNQEDETCPPDEIMEEAHTEVDVSSEKDDLGQ----EHQENDDMNSMDPKNDTSESSDVV 1696
++E+E+ P M++ +E+ + D G+ ++Q+ D + K E D
Sbjct: 1411 SDKEEESGPG---MDQGESELVAKDDNTDAGESNKDKNQDKDLPKDEEEKEKIHEQVDER 1467
Query: 1697 NPQVSNVDLASQSKSDLQTSGSENIASQSNLSNSHHDFGNPAVTGGFPSSDMSEMDINMS 1756
+ VD + + + + NL D P ++D +
Sbjct: 1468 EFDENEVDPYHGKQEKKAEPEAMELPEELNLDEDGKDEEGEEANEENP----FDIDDKLM 1523
Query: 1757 DSSNTGGFSKTQPK---SHLPQHEHSFSQEKQTNPSRSTGDALDFRK-EKINVSGDLPED 1812
+ G K +P+ + + QE++ +T + + K E + D +
Sbjct: 1524 EVDEKTGEDKGEPEEGGDEMTDEQQQEGQEEEHGEEDNTEEKEEAEKSEDQDPEMDERGE 1583
Query: 1813 NIEHHGEMDDNNADEYGYVSEFEKGTTQALGPATLEQVDRNIDVDKVDTESRAGEDANLQ 1872
N E + N E G + Q P E D + D +D+ R ++ Q
Sbjct: 1584 NEEEDDNKEKNKGQEEGREEDKSIPADQGQEPKKEEDGDED-DEAPLDSAERKEHASDGQ 1642
Query: 1873 LEKQNSEIDSVSNSSLLPKNEKRDQANMPVMEKSQDDGSVKPLGSANIDPESHLEDLISI 1932
++N + D+ L ++DQA ++DGS S + +S L +S
Sbjct: 1643 TGEENVQSDTA--VELAGAASEKDQA-------KEEDGSGAADASQSEGHDSKLMARMS- 1692
Query: 1933 SRSYLGENTHKLSQ---LSVNDEELGKYHE 1959
S+ +NT + + N+ +G Y+E
Sbjct: 1693 SQKQRQKNTQSFKRKPGQADNERSMGDYNE 1722
Score = 48.1 bits (113), Expect = 0.004
Identities = 62/290 (21%), Positives = 120/290 (41%), Gaps = 30/290 (10%)
Query: 1447 MQKKEEQEESKEVPGN-DNTGIEMDQDFQADAVSLSEDSSENEDCD-------GENEELE 1498
M +++QE +E G DNT + + + D ++ ENE+ D G+ E E
Sbjct: 1543 MTDEQQQEGQEEEHGEEDNTEEKEEAEKSEDQDPEMDERGENEEEDDNKEKNKGQEEGRE 1602
Query: 1499 SEMG-PTGPDSEAVGEKIWDQNEDETPDDTGEKYESGPSVKDGDGSNKELRAKDDSTSDQ 1557
+ P E E+ D+ +DE P D+ E+ E DG E + D+ +
Sbjct: 1603 EDKSIPADQGQEPKKEEDGDE-DDEAPLDSAERKEHA-----SDGQTGEENVQSDTAVEL 1656
Query: 1558 SG----DDSCDEGDAQNDEAAAQNEFDDEENGDDVNMDKE-AAHSDATGLKPDEPDHSSD 1612
+G D E D A+Q+E D + ++ K+ ++ + KP + D+
Sbjct: 1657 AGAASEKDQAKEEDGSGAADASQSEGHDSKLMARMSSQKQRQKNTQSFKRKPGQADNERS 1716
Query: 1613 M-EIDLNANEDVDPIEEGDQEGHDDSAENGNQEDETC----PPDEIMEEAHTEVDVSSEK 1667
M + + N+ + +++ +Q+ D + + QE + DE + +V ++
Sbjct: 1717 MGDYNERVNKRLRTVDKTEQKTQDQTQPDTQQESDLYEHIKQGDERYDAQTYDVASKEQQ 1776
Query: 1668 DDLGQEHQENDD-----MNSMDPKNDTSESSDVVNPQVSNVDLASQSKSD 1712
G + +E D+ M + K+ + + + P+ N + ASQ D
Sbjct: 1777 KPTGVKQEEEDEEDDIAMEVEEEKDLQAVEAQELKPEKLNDNKASQKGLD 1826
>ref|XP_485364.2| PREDICTED: midasin [Mus musculus]
Length = 4434
Score = 291 bits (746), Expect = 1e-76
Identities = 246/927 (26%), Positives = 412/927 (43%), Gaps = 142/927 (15%)
Query: 1448 QKKEEQEESKEVPGNDNTGIEMDQDFQADAVSLS-EDSSENEDCDGENEELESEMGP-TG 1505
+K EE +SK ++ IEM +DF E ++E D E+ +L+ +MG G
Sbjct: 3549 EKDEEDLDSKPDTKGEDNAIEMSEDFDGKMHDGELEQEEDDEKSDSEDGDLDKQMGNLNG 3608
Query: 1506 PDSEAVGEKIWDQNEDETPDDTGEKYESGPSVKDGDGSNKELRAKDDSTS---------- 1555
+++ + E++W +E+E D G E+GP V + D EL AKDDS
Sbjct: 3609 EEADKLDERLWGDDEEEDEDGDGRAEETGPGVDEEDS---ELVAKDDSLDAGNLNKNKKH 3665
Query: 1556 ----DQSGDDSCDEGDAQNDEAAAQNEFDDEE----NGDDVNMDKEAAHSDATGLKPDEP 1607
+ S + ++G + +E + E+D+ E +G+ + + A LK D
Sbjct: 3666 QDEKEDSEPEDVEQGQEKINEQIDEREYDENEVDPYHGNQEKLPEPEALDLPDDLKLDSE 3725
Query: 1608 DHSSDMEIDLNANEDVDPIE------EGDQEGHDDSAENGNQEDETCP--PDEIMEEAHT 1659
D S + D E+ +P+E + ++ H+ Q++ P P+E E
Sbjct: 3726 DKSGGEDTDNEEAEEENPLEIKEKTVDMEETDHEIEEPGAGQDEGESPHEPEEGPSEDKE 3785
Query: 1660 EVDVSSEKDDL-------GQEHQENDDMNSMDPKNDTSESSDV--------VNPQVSNVD 1704
+D+ + DD +EH ++ + K + E VNP +
Sbjct: 3786 NMDMDTGADDQDRDTSSHAEEHSLEEEAEEEEEKGEKEEDKATTDGGGESGVNPVDQGLQ 3845
Query: 1705 LASQSKSDLQTSGSENIASQSNLSNSHHDFGNPAV-----------TGGFPSSDMSE--- 1750
+ + + + S +E ++ H G V G P + +
Sbjct: 3846 PQKEEEEEGEQSDAEEQVPEATERKEHATCGQTGVDNVQSAQAVELAGAAPEKEQGKEEH 3905
Query: 1751 ----MDINMSDSSNTGGFSKTQPKSHLPQHEHSFSQEK-QTNPSRSTGDALDFRKEKINV 1805
D N ++ + ++ + H ++ SF + Q + RS GD + ++++
Sbjct: 3906 GSGAADANQAEGHESNLIARLSSQQHTNKNTQSFKRRPGQADNERSVGDYNERVRKRLRT 3965
Query: 1806 SGDLPE-------------DNIEHHGEMDDN-NADEYGYVSEFEKGTTQALGPATLEQVD 1851
G E D EH + D +A Y S ++ T +A G E+
Sbjct: 3966 VGTDRETEQEPTQAQVEDADAFEHVKQGSDAYDAQTYDVASSEQQQTAKASGQDQEEEEI 4025
Query: 1852 RNIDVDKVDTESRAGEDANLQLEKQNSEIDSVSNSSLLPKNEKRDQANMPVMEKSQDDGS 1911
+I +D + RA + L+ E SE + S SS + + D + E +
Sbjct: 4026 EDILMDTEEELMRAEDTEQLKPEAVQSETAATSGSSEM----EVDMQTLKTKEDQDPRTT 4081
Query: 1912 VKPLGSANIDPESHLEDLISISRSYLGENTHK--LSQLSVNDEELGKYHEPCDAPDH--- 1966
+ N PE + I R +L ++ + L +S +E+ + E A D+
Sbjct: 4082 TPHQETENERPERSRDSTIHTLRQFLVDSVFQPILKDISELRQEMERQLETWQAHDYGNA 4141
Query: 1967 -VKDNATALWRRYELSTTKLSQELTEQLRLVLEPTVASKLQGYYKTGKRIHMKKVIQFIA 2025
+ A +W+ Y + T LSQ+L EQLRL+LEPT A+KL+G Y+TGKR++M+K+I +IA
Sbjct: 4142 EEEKAAAEMWQNYLVLTASLSQQLCEQLRLLLEPTQAAKLRGDYRTGKRLNMRKIIPYIA 4201
Query: 2026 SYYRMDKIWLRRTRPNKRDYQVVIAVDDSHSMSESCCGDVAVEALVTVCRAVSQLEMGSL 2085
S +R D+IWLRRT+P+KR YQ+ +A+DDS SM ++ +A E+L + A++ LE+G +
Sbjct: 4202 SQFRKDRIWLRRTKPSKRQYQICLAIDDSSSMVDNHTKQLAFESLAVIGNALTLLEVGQI 4261
Query: 2086 AVASFGTKGNINLLHDFDSPFTAESGVKVSRIYTSLVFFFIDISTVHLLNMLKGSDCSFL 2145
AV SFG ++ LLH F F SG + R+
Sbjct: 4262 AVCSFGE--SVKLLHPFHEQFNDSSGTHILRL---------------------------- 4291
Query: 2146 TEEQMVSNLTFKQENTIADEPVVDLLKFLTNKLDAAVVKARLPSGHNP-LQQLVLIIADG 2204
TF+Q T + +FL +L +P QL+LI++DG
Sbjct: 4292 --------CTFQQRKT-------KIAQFLETVAKMFAAAQKLSQNVSPETAQLLLIVSDG 4336
Query: 2205 R---FHEKDNLKRCVREALASNRMVAFLLLDN--SQESIMDLMEASFEG-GKM-KFSKYM 2257
R KD + V+ A +N V F++LDN S++SI+D+ F+G G+M + YM
Sbjct: 4337 RGLFLEGKDRVLAAVQAAQNANIFVIFVVLDNPNSRDSILDIKVPIFKGPGEMPEIRSYM 4396
Query: 2258 DSFPFPYYIVLRNIEALPRTLANLLRQ 2284
+ FPFP+YI+LR++ ALP TL++ LRQ
Sbjct: 4397 EEFPFPFYIILRDVNALPETLSDALRQ 4423
Score = 166 bits (420), Expect = 9e-39
Identities = 175/806 (21%), Positives = 321/806 (39%), Gaps = 99/806 (12%)
Query: 127 GCAWAHIGALRIHLLLSYNEVDPVMKYYCKYTQLEETISSLELEIQVRKECGYLS----- 181
G W +G L+I L DP +K K ++ + L+ E++ R +L
Sbjct: 1973 GRLWVSLGLLQIQTWLPRARFDPAVKKAYKLRYAQDELRQLQCELKTRNLLSHLQTGRDL 2032
Query: 182 -GQFLTVEAD---KRKAERLEKLQAELRKLQRKIVFRSESWKYKKLMNECDEFLKHIASL 237
+T + K +R+ +L++ + L +K FR Y+ L+ E ++ IA +
Sbjct: 2033 EDDIITSHSHPHIKLLPQRISQLESLVHSLSKKQAFRPHLPSYETLVQEIHHYVTSIAKV 2092
Query: 238 EVLV-------------GNVEAEDLQQVIDRTHSWQETAMCFINRLTDEYTAYNDIIQPI 284
+ G A+ LQ ++ SWQ++ F RL +EY Y D + P+
Sbjct: 2093 TAVQDLLMRLLQALHTDGPKSAQVLQNLLKEEASWQQSHHQFRKRLVEEYALYPDTVAPL 2152
Query: 285 QVAVYEMKFGLSLVLSSFLEKEYLRKVGHENINLVTDMIYILMRFPRAASW--KFISVED 342
++ +++ G+ LV S + + EN+ + + + FP + + D
Sbjct: 2153 LASILQLQHGMRLVASEVHASLHSGVLCAENLGALAMAV---LAFPSVGPSFPTYHAHAD 2209
Query: 343 VGVDLHSSYKLDFGTDFYLNMGLIERLITLSSGVSADKKVSAMRCRASIYWNILVQIAYS 402
++++ L L + ++ ++ K A R + N L+ +
Sbjct: 2210 ALCSVNAAEAL---------RSLGKLMVKRAARKEEAKSQQAYPTREQLLMNALLYLRSH 2260
Query: 403 IANAKIIDRESYMLLHKIFDEFASLWMSMKVYAKSKSDHDAQQFKFKPR----AFQIESI 458
+ +D+ + +L + E + W + A+ K++ ++ ++++ R A E
Sbjct: 2261 VLCKGELDQRALLLFRHLCQEIINEWDEQERIAQEKAEQESSLYRYRSRSGRTALSEEEE 2320
Query: 459 MELEIPALANSSATEAFSDWKEFSYEEKSADNMESSEECEILDEEWKHLEESILDNVVLI 518
ELE+ L + E + EEK + EE + L +S + V+LI
Sbjct: 2321 EELELRKLFPLHEKDFADILMEPTLEEKKKVSDGREEEAA---PDPTLLCQSSMQAVMLI 2377
Query: 519 HSQLFGS--GDLVQAPGIFEISDEDRLHSFSESYKLGINLIKGAHSSNLASLDAKLIPEH 576
H QL S L + + L F Y+ G +L+ + L+ +L+
Sbjct: 2378 HQQLCLSFARSLWYQQAVPPHEAKHYLSLFLSCYQTGASLVTHFYPLMGVELNDQLLGSQ 2437
Query: 577 LFYLSIDYRRKFHSSSKSA-----NRYNFYKDSNAHEIEQMLKVLAPLRQQITSLLNEWE 631
L ++ ++ Y+FY+ N E Q VL + ++ LL +W
Sbjct: 2438 LLACTLSSNTLCGEATSDLMMRPDGPYDFYQHPNVAEARQCQPVLQGFSEAVSQLLQDWP 2497
Query: 632 EQNDLQRFLDVIDMLLTLPSDIPLAKAFSGLQFLLHKAQVMQENHSK-FTFSNQLKSVFD 690
E LQ+ L V+D + P P++K +GL+ LL KAQ +EN S+ + L V
Sbjct: 2498 EHPVLQQLLVVMDRIRGFPLSSPISKFLNGLEILLAKAQDWEENASRVLSLRKHLDLVSQ 2557
Query: 691 LMSSWHKMELGSWPVLLDEVMDQYENNAKKSVLSSSIHYF*SINFPKSNFYFSYES---- 746
++ W K+EL W + LD M ++ + K H+F + + E
Sbjct: 2558 MIIRWRKLELNCWSMSLDNTMIRHTEKSTK-------HWFSIYQMLEKHMQERTEEQEDD 2610
Query: 747 ---------CSLEDFIQTSSFGEFRKRLQLLYAFLGQNHTSACLKINSSNIVFFLHCWTL 797
+L+ FI+ SS GEF RLQ+L F HC L
Sbjct: 2611 KQMTLMLLVSTLQAFIEGSSLGEFHVRLQMLLVF---------------------HCHVL 2649
Query: 798 QLLSDGAVNILVQYVWILCAVLTNHIDASRKEIL-------TELKDLVKLCRWEQDKSYS 850
+ + L +W L +D + +I+ ELK+ VK+ +W +S
Sbjct: 2650 LMPQVEGKDSLCSVLWNLYHFYKQFLDPVKAKIMELRSPIEKELKEFVKISKWNDVSFWS 2709
Query: 851 SIENLKKSRQKLKKLIKKHTDILQEP 876
++++K+ + L K +KK +L EP
Sbjct: 2710 IKQSVEKTHRTLFKFMKKFEAVLSEP 2735
>ref|NP_013207.1| Huge dynein-related AAA-type ATPase (midasin), forms extended pre-60S
particle with the Rix1 complex (Rix1p-Ipi1p-Ipi3p), may
mediate ATP-dependent remodeling of 60S subunits and
subsequent export from nucleoplasm to cytoplasm; Mdn1p
[Saccharomyces cerevisiae] gi|1360494|emb|CAA97671.1|
unnamed protein product [Saccharomyces cerevisiae]
gi|1256854|gb|AAB67548.1| Ylr106cp [Saccharomyces
cerevisiae] gi|2132688|pir||S64942 probable membrane
protein YLR106c - yeast (Saccharomyces cerevisiae)
gi|24211972|sp|Q12019|MDN1_YEAST Midasin
(MIDAS-containing protein)
Length = 4910
Score = 290 bits (743), Expect = 3e-76
Identities = 236/889 (26%), Positives = 413/889 (45%), Gaps = 128/889 (14%)
Query: 1448 QKKEEQEESKEVPGNDNTGIEMDQDFQADAVSLSE-DSSENEDCDGENEELESEMGPTGP 1506
+ KE+Q++ + N++ +EM+ D + LS + +++ED D E EEL+ E+
Sbjct: 4090 ENKEQQDKDERDDENEDDAVEMEGDMAGELEDLSNGEENDDEDTDSEEEELDEEIDDLNE 4149
Query: 1507 DS-EAVGEKIWDQ--NEDETPDDTGEKYESGPSVKDGDGSNKELRAKD-------DSTSD 1556
D A+ +K+WD +++ DT + + +D + + + +D D +
Sbjct: 4150 DDPNAIDDKMWDDKASDNSKEKDTDQNLDGKNQEEDVQAAENDEQQRDNKEGGDEDPNAP 4209
Query: 1557 QSGDDSCDE---GDAQNDEAAAQNEFDDEENGD---------------DVNMDKEAAHSD 1598
+ GD+ + + +ND ++E DEE D D+N+D E SD
Sbjct: 4210 EDGDEEIENDENAEEENDVGEQEDEVKDEEGEDLEANVPEIETLDLPEDMNLDSEHEESD 4269
Query: 1599 ATGLKPDEPDHSSDMEIDLN----ANEDVDPIEEGDQEGHDDSAENGNQEDETCPPDEIM 1654
++ D S M DLN NED + +E E +++ E G +ED +
Sbjct: 4270 ------EDVDMSDGMPDDLNKEEVGNEDEEVKQESGIESDNENDEPGPEEDAGETETALD 4323
Query: 1655 EEAHTEVDVSSEKDDLGQEHQENDDMNSMDPKNDTSESSDVVNPQVSNVDLASQSKSDLQ 1714
EE E DV D+ G+E +EN + + S + Q + ++ + +
Sbjct: 4324 EEEGAEEDVDMTNDE-GKEDEENGP-------EEQAMSDEEELKQDAAMEENKEKGGEQN 4375
Query: 1715 TSGSENIASQSNLSNSHHDFGNPAVTG----GFPSSDMSEMDINMSDSSNTGGFSKTQPK 1770
T G + + +++ + + +G G ++D E D + GG TQ
Sbjct: 4376 TEGLDGVEEKADTEDIDQEAAVQQDSGSKGAGADATDTQEQD-------DVGGSGTTQNT 4428
Query: 1771 SHLPQHE----HSFSQEKQTNPSRSTGDAL-DFRKEKINVSGDLPEDNIEHHGEMDDNNA 1825
Q + + S+E+ T + GD++ ++ + + ++ + + E ++
Sbjct: 4429 YEEDQEDVTKNNEESREEATAALKQLGDSMKEYHRRRQDIKEAQTNGEEDENLEKNNERP 4488
Query: 1826 DEYGYVSEFEKGT-TQALGPATLEQVDRNIDVDKVDTESRAGEDANLQ--LEKQNSEIDS 1882
DE+ +V T TQALG AT +Q+ + ID D + R ++ + + +E + E
Sbjct: 4489 DEFEHVEGANTETDTQALGSATQDQL-QTIDEDMAIDDDREEQEVDQKELVEDADDEKMD 4547
Query: 1883 VSNSSLLPKNEKRDQANMPVMEKSQDDGSVKPLGSANIDPESHLEDLISISRSYLGENTH 1942
+ +L + D N +KS G K E +L + S E+
Sbjct: 4548 IDEEEMLSDIDAHDANNDVDSKKSGFIGKRK-------SEEDFENELSNEHFSADQEDDS 4600
Query: 1943 KLSQLSVNDEELGKYHEPCDAPDHVKDNATALWRRYELSTTKLSQELTEQLRLVLEPTVA 2002
++ L N E+ P+ + + LW + E+ST L L EQLRL+LEPT+A
Sbjct: 4601 EIQSLIENIEDNPPDASASLTPERSLEESRELWHKSEISTADLVSRLGEQLRLILEPTLA 4660
Query: 2003 SKLQGYYKTGKRIHMKKVIQFIASYYRMDKIWLRRTRPNKRDYQVVIAVDDSHSMSESCC 2062
+KL+G YKTGKR++MK++I +IAS +R DKIWLRRT+P+KR YQ++IA+DDS SMSES C
Sbjct: 4661 TKLKGDYKTGKRLNMKRIIPYIASQFRKDKIWLRRTKPSKRQYQIMIALDDSKSMSESKC 4720
Query: 2063 GDVAVEALVTVCRAVSQLEMGSLAVASFGTKGNINLLHDFDSPFTAESGVKVSRIYTSLV 2122
+A ++L V + ++QLE G L++ FG NI +H FD F+ ESG + + +
Sbjct: 4721 VKLAFDSLCLVSKTLTQLEAGGLSIVKFGE--NIKEVHSFDQQFSNESGARAFQWF---- 4774
Query: 2123 FFFIDISTVHLLNMLKGSDCSFLTEEQMVSNLTFKQENTIADEPVVDLLKFLTNKLDAAV 2182
F++ T + V + K + + A V
Sbjct: 4775 --------------------------------GFQETKTDVKKLVAESTK-IFERARAMV 4801
Query: 2183 VKARLPSGHNPLQQLVLIIADGRFHEKDNLKRCVREALASNRMVAFLLLD--NSQESIMD 2240
HN QL ++I+DG + + +++ VR A + M+ F+++D S ESI+D
Sbjct: 4802 --------HNDQWQLEIVISDGICEDHETIQKLVRRARENKIMLVFVIIDGITSNESILD 4853
Query: 2241 LMEAS-----FEGGKMKFSKYMDSFPFPYYIVLRNIEALPRTLANLLRQ 2284
+ + + + ++K +KY+D+FPF +Y+V+ +I LP L+ +LRQ
Sbjct: 4854 MSQVNYIPDQYGNPQLKITKYLDTFPFEFYVVVHDISELPEMLSLILRQ 4902
Score = 87.4 bits (215), Expect = 5e-15
Identities = 109/506 (21%), Positives = 204/506 (39%), Gaps = 59/506 (11%)
Query: 446 FKFKPRAFQIESIMELEIPALANSSATEAFSDWKEFSYEEKSADNMESSEECEILDEEWK 505
FKF R + I E + L + + F +E E + ++ + ++ + + +++
Sbjct: 3123 FKFHKRDTNLLEIFEAALYTLYSRWSVRRFRQEQE---ENEKSNMFKFNDNSDDYEADFR 3179
Query: 506 HLEESILDNVVLIHSQLFGSGDLVQ------APGIFEISDEDRLHSFSESYKLG--INLI 557
L D ++ + + S + + A + D+D +FS K G I I
Sbjct: 3180 KLFPDYEDTALVTNEKDISSPENLDDIYFKLADTYISVFDKDHDANFSSELKSGAIITTI 3239
Query: 558 KGAHSSNLASLDAKLIPEHLFYLSIDYRRKFHSSSKSANRYNFYKDSNAHEIEQMLKVLA 617
N + K ++D + +++ +FY D + E ++ ++
Sbjct: 3240 LSEDLKNTRIEELKSGSLSAVINTLDAETQSFKNTEVFGNIDFYHDFSIPEFQKAGDIIE 3299
Query: 618 PLRQQITSLLNEWEEQNDLQRFLDVIDMLLTLPSDIPLAKAFSGL-QFLLHKAQVMQENH 676
+ + + LL +W E L+ V L P PLA+ + Q + A+ +
Sbjct: 3300 TVLKSVLKLLKQWPEHATLKELYRVSQEFLNYPIKTPLARQLQKIEQIYTYLAEWEKYAS 3359
Query: 677 SKFTFSNQLKSVFDLMSSWHKMELGSWPVLLDEVMDQYENNAKKSVLSSSIHYF*SINFP 736
S+ + +N +K + DL+ SW K+EL +W L + + +KS+ + + SI
Sbjct: 3360 SEVSLNNTVKLITDLIVSWRKLELRTWKGLFNSE----DAKTRKSIGKWWFYLYESIVI- 3414
Query: 737 KSNFYFSYESC---------SLEDFIQTSSFGEFRKRLQLLYAFLGQNHTSACLKINSSN 787
SNF + SL F S+ GEF RL L+ AF H + + SS
Sbjct: 3415 -SNFVSEKKETAPNATLLVSSLNLFFSKSTLGEFNARLDLVKAFY--KHIQL-IGLRSSK 3470
Query: 788 IVFFLHCWTLQLLSDGAVNILVQYVWILCAVLTNHIDASRKEILTELKDLVKLCRWEQDK 847
I LH + Q+ ++ +TN +K + E+ D++ L W+
Sbjct: 3471 IAGLLH---------NTIKFYYQFKPLIDERITN----GKKSLEKEIDDIILLASWKDVN 3517
Query: 848 SYSSIENLKKSRQKLKKLIKKHTDILQEPMDKLIRDVLHKGSISGVSDLPLFSDENRLYQ 907
+ ++ +KS L K+++K+ D+L +I L L+S+EN+L
Sbjct: 3518 VDALKQSSRKSHNNLYKIVRKYRDLLNGDAKTIIEAGL------------LYSNENKLKL 3565
Query: 908 EGWKDVWHMIENIYIKAVDSGNIWKE 933
K H E+ ++A S N+ KE
Sbjct: 3566 PTLKQ--HFYEDPNLEA--SKNLVKE 3587
Score = 68.2 bits (165), Expect = 3e-09
Identities = 100/489 (20%), Positives = 193/489 (39%), Gaps = 64/489 (13%)
Query: 1540 GDGSNKELRAKDDSTSDQSGDDSCDEGDAQNDEAAAQNEFDDEENGDDVNMDKEAA---H 1596
GDG + KD + +D+ +E Q D ++E DDE D V M+ + A
Sbjct: 4065 GDGEGAQNNNKDVEQDEDLTEDAQNENKEQQD----KDERDDENEDDAVEMEGDMAGELE 4120
Query: 1597 SDATGLKPDEPDHSSDMEIDLNANEDVDPIEEGDQEG-----HDDSAENGNQEDETCPPD 1651
+ G + D+ D S+ E +E++D + E D DD A + ++E +T D
Sbjct: 4121 DLSNGEENDDEDTDSEEE---ELDEEIDDLNEDDPNAIDDKMWDDKASDNSKEKDT---D 4174
Query: 1652 EIMEEAHTEVDV-SSEKDDLGQEHQENDDMNSMDPKNDTSESSDVVNPQVSN------VD 1704
+ ++ + E DV ++E D+ ++++E D + P++ E + N + N +
Sbjct: 4175 QNLDGKNQEEDVQAAENDEQQRDNKEGGDEDPNAPEDGDEEIENDENAEEENDVGEQEDE 4234
Query: 1705 LASQSKSDLQTSGSE----NIASQSNLSNSHHDFGNPA-VTGGFPSSDMSEMDINMSDSS 1759
+ + DL+ + E ++ NL + H + ++ G P D+N +
Sbjct: 4235 VKDEEGEDLEANVPEIETLDLPEDMNLDSEHEESDEDVDMSDGMPD------DLNKEEVG 4288
Query: 1760 NTGGFSKTQPKSHLPQHEHSFSQEKQTNPSRSTGDALDFRKEKINVSGDLPEDNIEHHGE 1819
N K + E+ + + D + +E ++++ D +++ E+ E
Sbjct: 4289 NEDEEVKQESGIESDNENDEPGPEEDAGETETALDEEEGAEEDVDMTNDEGKEDEENGPE 4348
Query: 1820 ---MDDNNADEYGYVSEFEKGTTQALGPATLEQVDRNIDVDKVDTESRAGEDANLQ---- 1872
M D + E K L+ V+ D + +D E+ +D+ +
Sbjct: 4349 EQAMSDEEELKQDAAMEENKEKGGEQNTEGLDGVEEKADTEDIDQEAAVQQDSGSKGAGA 4408
Query: 1873 LEKQNSEIDSVSNSSLLPKNEKRDQANMPV-MEKSQDD--GSVKPLGSANIDPESHLEDL 1929
E D V S + DQ ++ E+S+++ ++K LG + + +D+
Sbjct: 4409 DATDTQEQDDVGGSGTTQNTYEEDQEDVTKNNEESREEATAALKQLGDSMKEYHRRRQDI 4468
Query: 1930 ISISRSYLGENTHKLSQLSVNDEELGKYHEPCDAPDHVKDNATALWRRYELSTTKLSQEL 1989
+ GE DE L K +E D +HV+ T E T L
Sbjct: 4469 KEAQTN--GE----------EDENLEKNNERPDEFEHVEGANT------ETDTQALGSAT 4510
Query: 1990 TEQLRLVLE 1998
+QL+ + E
Sbjct: 4511 QDQLQTIDE 4519
Score = 60.5 bits (145), Expect = 7e-07
Identities = 81/387 (20%), Positives = 154/387 (38%), Gaps = 52/387 (13%)
Query: 1555 SDQSGDDSCDEGDAQNDEAAAQNEFDDEENGDDVNMDKEAAHSDATGLKPDEPDHSSDME 1614
S++ D + EG D AQN D E +D+ D + + + K + D + D
Sbjct: 4050 SEEVDDKNLQEGTGLGDGEGAQNNNKDVEQDEDLTEDAQNENKEQQD-KDERDDENEDDA 4108
Query: 1615 IDLNANEDVDPIEEGDQEGHDDSAENGNQEDETCPPDEIMEEAHTEVDVSSEKDDLGQEH 1674
+++ EGD G + NG + D DE + E+D E DDL +
Sbjct: 4109 VEM----------EGDMAGELEDLSNGEEND-----DEDTDSEEEELD--EEIDDLNE-- 4149
Query: 1675 QENDDMNSMDPKNDTSESSDVVNPQVSNVDLASQSKSDLQTSGSENIASQSNLSNSHHDF 1734
DD N++D K ++SD + ++ +L +++ + +EN Q + +
Sbjct: 4150 ---DDPNAIDDKMWDDKASDNSKEKDTDQNLDGKNQEE-DVQAAENDEQQRDNKEGGDED 4205
Query: 1735 GNPAVTG---------GFPSSDMSEMDINMSDSSNTGGFSKTQPKSH---LPQHEHSFSQ 1782
N G +D+ E + + D P+ LP+ + S+
Sbjct: 4206 PNAPEDGDEEIENDENAEEENDVGEQEDEVKDEEGE-DLEANVPEIETLDLPEDMNLDSE 4264
Query: 1783 EKQTNPSRSTGDAL--DFRKEKINVSGDLPEDNIEHHGEMDDNNADEYGYVSEFEKGTTQ 1840
++++ D + D KE++ G+ E+ + G DN DE G E + G T+
Sbjct: 4265 HEESDEDVDMSDGMPDDLNKEEV---GNEDEEVKQESGIESDNENDEPG--PEEDAGETE 4319
Query: 1841 ALGPATLEQVDRNIDVDKVDTESRAGEDANLQLEKQNSEIDSVSNSSLLPKNEKRDQANM 1900
A E+ DVD + E + E+ + + + E + ++++ EK + N
Sbjct: 4320 T---ALDEEEGAEEDVDMTNDEGKEDEENGPEEQAMSDEEELKQDAAMEENKEKGGEQNT 4376
Query: 1901 PVMEKSQDDGSVKPLGSANIDPESHLE 1927
+ DG + + +ID E+ ++
Sbjct: 4377 EGL-----DGVEEKADTEDIDQEAAVQ 4398
>emb|CAG98681.1| unnamed protein product [Kluyveromyces lactis NRRL Y-1140]
gi|50311883|ref|XP_455973.1| unnamed protein product
[Kluyveromyces lactis]
Length = 4915
Score = 286 bits (732), Expect = 6e-75
Identities = 246/882 (27%), Positives = 422/882 (46%), Gaps = 115/882 (13%)
Query: 1448 QKKEEQEESKEVPGNDNTGIEMDQDFQADAVSLSEDSSENEDCDGEN--EELESEMGPTG 1505
Q+ + E+ +E ++ +EM+ D D + S+ +E ED + E+ +EL+ E+
Sbjct: 4096 QRNDSDEDDEE---KEDDAVEMEGDIAGDLENASDQENEEEDDNNEDDEDELDEEIDNLD 4152
Query: 1506 PDS-EAVGEKIWDQNEDETPDDTGEK-YESGPSVKDGDG-SNKELRAKDD-STSDQSGDD 1561
D A+ EK+W E+E DD+ EK E+ P + D E +A+DD D +
Sbjct: 4153 EDDPNALDEKMW---EEEAEDDSKEKDSENMPEKSNADDVQASEEQAEDDVKPEDHQQNQ 4209
Query: 1562 SCDEGDAQNDEAAAQNEFDDEENGDDVNMDKEAAHSDATGLKPDEPD-HSSDMEIDLNAN 1620
DE + + + E +EE D + E + + L+ + P+ + D+ D+N +
Sbjct: 4210 ETDEMETEEKDNDDDGEEQEEEEEDVGEQEDEVRNDENENLENNVPEVETMDLPEDMNLD 4269
Query: 1621 EDVDPIEEGDQEGHDDSAE--NGNQEDETCPPDEIMEEAHTEVDVSSEKDDLGQEHQEND 1678
D D E+G +E +D + ++E+E E E T +D S+ D+ +E E+
Sbjct: 4270 SDKDNEEDGSEEEEEDFEDKMEVDEEEEEGKQPENTENEQTNIDEESDADE-NRESDEDV 4328
Query: 1679 DMNSMDPKNDTSES----SDVVNPQVSNVDLASQSKSDLQTSGSENIASQSNLSNSHHDF 1734
DM+ D ++T E+ D P + +A S S+L+ E
Sbjct: 4329 DMDG-DDNSETEEALDKEDDTEKPDIKEEAIA-DSDSELENPQDEPKQEGGEDEKGEDVE 4386
Query: 1735 GNPAVTGGFPSSDMSEMDINMSDSSNTGG----FSKTQPKSHLPQHEHSFSQEKQTNPSR 1790
G + G D D + S G + ++ + + ++ SQ ++ N
Sbjct: 4387 GLDGLEGVEDDKDQINTDAAVEQDSGAKGEGSNAADSEEQQDIGSSGNAQSQSQENNQEE 4446
Query: 1791 STGDALDFRKEKINVSGDLPEDNIEHHGEM--------------DDNNADEYGYVSEFEK 1836
T + +E + GD ++ H E+ + DE+ +V
Sbjct: 4447 ITDTSRKDAQESLKQLGDSLKEFHRRHQEIKEASTNSEEQQPEGSNQKPDEFEHVDGANT 4506
Query: 1837 GT-TQALGPATLEQV---DRNIDVDKVDTESRA-GEDANLQLEKQNSEIDSVSNSSLLPK 1891
T TQALG A +Q+ D ++ +D+ E +A E+ N + +K +++ + P+
Sbjct: 4507 ETDTQALGSADKDQLTGFDEDLAIDEDSNEEKAEPENENDEDQKHPTDVMDIDE----PE 4562
Query: 1892 NEKRDQANMPVMEKSQDDGSVKPLGSANIDPESHLEDLISI-SRSYLGENTHKLSQ-LSV 1949
+ D ++ +++G K A I + LE+ ++ ++ + + + + Q L+
Sbjct: 4563 VQNGD------IDNEENNGKSK---GAFIGERNALENSGALWDQNDIVSDENDIDQILNE 4613
Query: 1950 NDEELGKYHEPCDAPDHVKDNATALWRRYELSTTKLSQELTEQLRLVLEPTVASKLQGYY 2009
D E+ + + AP D A LW+R E T +L+ L+EQLRL+LEPT+A+KL+G Y
Sbjct: 4614 VDNEVSEENSVAVAP-RPFDEARELWKRSEQETNELAAGLSEQLRLILEPTLATKLKGDY 4672
Query: 2010 KTGKRIHMKKVIQFIASYYRMDKIWLRRTRPNKRDYQVVIAVDDSHSMSESCCGDVAVEA 2069
KTGKR++MK++I +IAS YR DKIWLRRT+P+KR YQ++IAVDDS SMSES ++A ++
Sbjct: 4673 KTGKRLNMKRIIPYIASQYRKDKIWLRRTKPSKRQYQIMIAVDDSKSMSESKSVNLAFQS 4732
Query: 2070 LVTVCRAVSQLEMGSLAVASFGTKGNINLLHDFDSPFTAESGVKVSRIYTSLVFFFIDIS 2129
+ V +A++QLE G L++ FG + +H F+ PF ++G + F + D
Sbjct: 4733 ICLVSKALTQLESGGLSIVKFGE--TVREVHPFNQPFNTQTGAQ--------TFQWFD-- 4780
Query: 2130 TVHLLNMLKGSDCSFLTEEQMVSNLTFKQENTIADEPVVDLLKFLTNKLDAAVVKARLPS 2189
F++ T + V + +K +AR
Sbjct: 4781 --------------------------FQETRTDVKKLVAESIKIFE--------RARAME 4806
Query: 2190 GHNPLQQLVLIIADGRFHEKDNLKRCVREALASNRMVAFLLLD--NSQESIMDLMEASF- 2246
N L QL +II+DG + + L R VR A + M+ F+++D NS ESIMD+ + ++
Sbjct: 4807 S-NDLWQLEIIISDGVCEDHETLVRLVRRARENKIMLVFVVIDGINSNESIMDMSQVNYI 4865
Query: 2247 --EGGKMKFS--KYMDSFPFPYYIVLRNIEALPRTLANLLRQ 2284
+ G MK S KY+D+FPF +Y+V+ +I LP L+ +LRQ
Sbjct: 4866 PDQFGNMKLSVQKYLDTFPFEFYVVVHDITELPEMLSIILRQ 4907
Score = 85.9 bits (211), Expect = 2e-14
Identities = 171/912 (18%), Positives = 344/912 (36%), Gaps = 188/912 (20%)
Query: 126 IGCAWAHIGALRIHLLLSYNEVDPVMKYYCKYTQLEETISSLELEIQVRKECGYLSGQFL 185
+G AW + L + + DP ++ Y Y S E I K +G L
Sbjct: 2896 LGKAWVLFAVGLLQLYVPSSPYDPAIRDYVIYDNYVAHKSLTESIIHNWK----CAGSVL 2951
Query: 186 TVEADKRKAERLEKLQAELRKLQRKIVFRSESWKYKKLMNECDEFLKHIASLEVLVGNVE 245
+ D + + ++ ++ + ++ VFR L +E F+ + ++ +E
Sbjct: 2952 FGDVDSYTQKLVPEVSSD-DEPKKPRVFRPNH-SIDSLFDEWSAFMLSTVDVTPVISLLE 3009
Query: 246 AEDLQQVID--RTHSWQETAMCFINRLTDEYTAYNDIIQPIQVAVYEMKFGLSLVLSSFL 303
+ I R +++ F++RL+ Y Y+DI VY MKFG +++
Sbjct: 3010 SSTEYNSISDSRFKMFEQNTSQFLSRLSSTYEVYSDINDIFAGYVYAMKFGFNVI----- 3064
Query: 304 EKEYLRKVGHENINLVTDMIYILMRFPRAASWKFISVEDVGVDLHSSYKLDFGTDFYLNM 363
+G EN S +LD F ++
Sbjct: 3065 ------SLGAEN---------------------------------ESQELDISPLFTVDC 3085
Query: 364 GLIERLITLSSGVSADKKVSAMRCRASIYWNILVQIAYSIANAKIIDRESYMLLHKIFDE 423
+ R ++ S S +++ ++ + + +I N ++S ++ + +
Sbjct: 3086 LAVTREKSILSHFS---RLNKFLKNQNVGSHDVEEILIHFLNLCYAHKDSESMIDSLNEI 3142
Query: 424 FASLWMSMKVYAKSKSDHDAQQ----FKFKPRAFQIESIMELEIPALANSSATEAFSDWK 479
L+ + + KS+ +A+Q FKF + IE+ + P +S + ++
Sbjct: 3143 LQPLYYRWSL-RRMKSEQEAEQKNSLFKFNDNSDDIEAEFKAMFPDYEDSVSLDS----- 3196
Query: 480 EFSYEEKSADNMESSEECEILDEEWKHLEESILDNVVLIHSQLFGSGDLVQAPGIFEISD 539
+E S ++D ++ + I+ ++F V +
Sbjct: 3197 ----------PVEESSATSLIDTYYE---------IAKIYIEIFEDASNVSLSQVMRKGS 3237
Query: 540 EDRLHSFSESYKLGINLIKGAHSSNLASLDAKLIPEHLFYLSIDYRRKFHSSSKSANR-- 597
E + L++ L +L+ ++ + LS K +S S+N
Sbjct: 3238 ET-----------SVILLRSCSDFKLYNLNESMVLAAIKTLS----EKTNSFKDSSNTEI 3282
Query: 598 YNFYKDSNAHEIEQMLKVLAPLRQQITSLLNEWEEQNDLQRFLDVIDMLLTLPSDIPLAK 657
++FY+ ++ E ++ V+ L + +LL EW E L+ V ++ P P+A+
Sbjct: 3283 FDFYRGTSRIETKKAQHVIQGLWNNVNTLLKEWPEHATLRDLFRVCKEFISYPVSTPMAR 3342
Query: 658 AFSGL-QFLLHKAQVMQENHSKFTFSNQLKSVFDLMSSWHKMELGSWPVLLDEVMDQYEN 716
+ Q + + SK + + S+ +L+ SW ++EL +W L +
Sbjct: 3343 LLQKIEQIYTFVVEWQKYASSKVSLQAHVDSITNLIVSWRRLELHTWKALFQ----MEDM 3398
Query: 717 NAKKSVLSSSIHYF*SI--NFPKSNFYFSYESCSLED----FIQTSSFGEFRKRLQLLYA 770
N+ K++ + + F +I +N S S SL F S+ GEF RL+L+ A
Sbjct: 3399 NSTKTIGNWWFYLFETIIVGTENANIDVSERSGSLLSALNVFFSKSTLGEFANRLRLVKA 3458
Query: 771 FLGQNHTSACLKINSSNIVFFLHCWTLQLLSDGAVNILVQYVWILCAVLTNHIDASRKEI 830
F H S +H T ++S NI+ Y +V+ + I +K +
Sbjct: 3459 FC--KHVSV------------MHGKT-SIISQALQNIISFYEQFT-SVVNDKIKTGKKLL 3502
Query: 831 LTELKDLVKLCRWEQDKSYSSIENLKKSRQKLKKLIKKHTDILQEPMDKLI--------- 881
E+ +++ L W+ + ++ ++S L K+++K+ +L EP+ +I
Sbjct: 3503 EKEISEVILLASWKDVNIDALKQSSRRSHNSLFKIVRKYRTLLSEPLTSMIESGIDSALP 3562
Query: 882 -------------RDVLHKGSISGVSDLPLFSDENRLYQEGWKDVWHMIEN--IYIKAVD 926
R + G+ S V+++P + ++ KD++ +N IYI +
Sbjct: 3563 VTKQFERVTISHFRSIDVSGAKSIVTNIPGWESRSK----SLKDIYITQKNLSIYISKIT 3618
Query: 927 SGN------------------------IWKEDKNN------QRKSRALSDLLNLLKTSGL 956
+ N ++K++K +KS+ LSD L LK GL
Sbjct: 3619 NQNYPDLLEYALYISKEAKRLREETPTVYKKEKKKLLATLKTQKSKLLSDSLKELKRIGL 3678
Query: 957 SQ--RKSTHKVK 966
R+ K++
Sbjct: 3679 KSNFREDIRKIQ 3690
Score = 66.2 bits (160), Expect = 1e-08
Identities = 93/458 (20%), Positives = 193/458 (41%), Gaps = 55/458 (12%)
Query: 1521 DETPDDTGEKYESGPSVKDGDGSNKELRAKDDSTSDQSGDDSCDEGDAQNDEAAAQNEFD 1580
+ET D+ + G + DGDG A+++S + +D ++ N + ++ D
Sbjct: 4053 EETEDNN---LQEGTGLGDGDG------AQNNSKDVEEDEDLLEDAQQPNKDQRNDSDED 4103
Query: 1581 DEENGDD-VNMDKEAAHS--DATGLKPDEPDHSSDMEIDLNANEDVDPIEEGDQEGHDDS 1637
DEE DD V M+ + A +A+ + +E D +++ + D +E++D ++E D D+
Sbjct: 4104 DEEKEDDAVEMEGDIAGDLENASDQENEEEDDNNEDDED-ELDEEIDNLDEDDPNALDEK 4162
Query: 1638 AENGNQEDETCPPD-EIMEEAHTEVDVSS-----EKDDLGQEHQENDDMNSMDPKNDTSE 1691
ED++ D E M E DV + E D ++HQ+N + + M+ + +
Sbjct: 4163 MWEEEAEDDSKEKDSENMPEKSNADDVQASEEQAEDDVKPEDHQQNQETDEME--TEEKD 4220
Query: 1692 SSDVVNPQVSNVDLASQSKSDLQTSGSENIASQSNLSNSHHDFGNPAVTGGFPSSDMSEM 1751
+ D Q + + + +++ +EN+ ++N+ P V + D+ E
Sbjct: 4221 NDDDGEEQEEEEEDVGEQEDEVRNDENENL--ENNV---------PEV----ETMDLPE- 4264
Query: 1752 DINM-SDSSNTGGFSKTQPKSHLPQHEHSFSQEKQTNPSRSTGDALDFRKEKINVSGDLP 1810
D+N+ SD N S+ + + + E +E+ P + + + +E
Sbjct: 4265 DMNLDSDKDNEEDGSEEEEEDFEDKMEVDEEEEEGKQPENTENEQTNIDEESDADENRES 4324
Query: 1811 EDNIEHHGEMDDNNADEYGYVSEFEKGTTQALGPATLEQVDRNIDVDKVDTESRAGEDAN 1870
+++++ G DDN+ E E + A + D ++ + + + GED
Sbjct: 4325 DEDVDMDG--DDNSETEEALDKEDDTEKPDIKEEAIADS-DSELENPQDEPKQEGGEDEK 4381
Query: 1871 LQ-------LEKQNSEIDSVSNSSLLPKNE--KRDQANMPVMEKSQDDGSVKPLGSANID 1921
+ LE + D ++ + + ++ K + +N E+ QD GS S N
Sbjct: 4382 GEDVEGLDGLEGVEDDKDQINTDAAVEQDSGAKGEGSNAADSEEQQDIGS-----SGNAQ 4436
Query: 1922 PESHLEDLISISRSYLGENTHKLSQLSVNDEELGKYHE 1959
+S + I+ + + L QL + +E + H+
Sbjct: 4437 SQSQENNQEEITDTSRKDAQESLKQLGDSLKEFHRRHQ 4474
>emb|CAG82879.1| unnamed protein product [Yarrowia lipolytica CLIB99]
gi|50546232|ref|XP_500637.1| hypothetical protein
[Yarrowia lipolytica]
Length = 4696
Score = 282 bits (722), Expect = 8e-74
Identities = 257/914 (28%), Positives = 438/914 (47%), Gaps = 164/914 (17%)
Query: 1446 MMQKKEEQEESKEVPGNDNTGIEMDQDFQADAVSLSEDSSENEDCDGENEELESEMGP-T 1504
M Q+ E+QE+ + +D +E D +++ ++D E ED DGE EE E E+ T
Sbjct: 3863 MEQENEDQEDKDDDEDDDAVSVEGDMAGKSEN---AKDEEEGEDKDGEEEEEEEEIDDET 3919
Query: 1505 GP----DSEAVGEKIWDQNEDETPDDTGEKYESGPSVKDGDGSNKELRAKDDSTSDQSGD 1560
G D A+ +K+W N+DE D EK + G D DG +K+ ++ D G
Sbjct: 3920 GNLDDLDPNAMDDKMW--NDDEEVQD--EKEKDG----DVDGDDKDDGGEEGKQDD--GK 3969
Query: 1561 DSCDEGDAQNDEAAAQNEFDDEEN---GDDVNMDKEAAHSDATGLKPDEPDHSSDMEID- 1616
+EG+A+ E ++E + EEN GD+ +KE SD + E D + E D
Sbjct: 3970 QQGEEGEAETKEGEGEDEGEQEENEGDGDEGEQEKEEDDSDGESVDAQEDDVRNKQEGDE 4029
Query: 1617 ----LNANEDVDPIEEGDQEGHDDSAENGNQE-DETCPPDEIMEEAHTEVDVSSEKDDLG 1671
L+ +E ++ E+ + +G D+ E G E D+ D EE + DV E +DL
Sbjct: 4030 LDPHLDESEVLELPEDMNLDGMDEDKEEGEDEFDDGLDKDMSDEEGDGDEDVEMEDEDLN 4089
Query: 1672 ---QEHQENDDMNSMDPK----NDTSESSDVVNPQ-VSNV--DLASQSKSDL-----QTS 1716
+E +E D +D N+ E +D NP+ + NV D + K D+ +T
Sbjct: 4090 AGEEEPEEGADEEEVDEGAGEVNEDVEDADEKNPEEMDNVKEDAMEEEKMDVDQDDNETG 4149
Query: 1717 GSENIASQSNLSNSH--HDFGNPAVT------------GGFPSSDMSEMDINMSDSSNTG 1762
A + + H D G+ G +D E + ++ G
Sbjct: 4150 KQNEDAPELEMEGLHGQDDAGDQEENDESAVKQETGEKGSGQDADSKEEEEDVGGGGEAG 4209
Query: 1763 GFSKTQPKSH-------LPQHEHSFSQEKQTNPSRSTGDAL-DFRKEKINVSGDLPEDNI 1814
+ Q + + + +++ + + + GDAL +F K+K + +N
Sbjct: 4210 AKEEDQDEDQDEDQDDKTKEGQEDDAEDSRVDQMKQLGDALKEFHKKKEEIKNS---NND 4266
Query: 1815 EHHGEMDDNNAD--EYGYVSEFE-KGTTQALGPATLEQVDRNIDVDKVDTESRAGEDANL 1871
++D N D E+ +V + K TQA+G A DR++ D D + E +
Sbjct: 4267 SAQDDVDSANVDPQEFEHVDGPDSKHDTQAMGAA-----DRDVKQDIDDDMAMEDEQEEV 4321
Query: 1872 QLEKQNSEIDSVSNSSLLPKNEKRDQANMPVMEKSQDDGSVKPLGSAN---IDPESHLED 1928
+ E++N K E+ ++ E +D G+ P G+A+ ++ E+ +D
Sbjct: 4322 KPERRNEV-----------KQEEGEEPEEDAEEADEDGGA--PEGAASKTAVEGEAESDD 4368
Query: 1929 LISISRSYLGENTHKLSQLSVNDEELGKYHEPCDAPD-HVKDNATAL------WRRYELS 1981
+ S+ GE + ++ ++EEL + E D D + ++A +L W+ Y+ S
Sbjct: 4369 EEAESKVQ-GE----MMEVDSDEEELEEVEE--DIEDLSIDESAMSLSESRDKWKTYQSS 4421
Query: 1982 TTKLSQELTEQLRLVLEPTVASKLQGYYKTGKRIHMKKVIQFIASYYRMDKIWLRRTRPN 2041
L+ L EQLRL+LEPT+A+K++G +KTGKR++MK++I +IAS ++ DKIW+RRT+P+
Sbjct: 4422 VADLATTLCEQLRLILEPTLATKMRGDFKTGKRLNMKRIIPYIASSFKKDKIWMRRTKPS 4481
Query: 2042 KRDYQVVIAVDDSHSMSES-CCGDVAVEALVTVCRAVSQLEMGSLAVASFGTKGNINLLH 2100
KR YQ++I+VDDS SM+ES C ++A +++ + +A++QLE G LAV FG + L+H
Sbjct: 4482 KRQYQIMISVDDSKSMNESPQCVELAFQSIALISKALTQLESGQLAVMKFGQ--DAQLVH 4539
Query: 2101 DFDSPFTAESGVKVSRIYTSLVFFFIDISTVHLLNMLKGSDCSFLTEEQMVSNLTFKQEN 2160
F+ F+ ESG ++VS +F Q+
Sbjct: 4540 PFEKTFSDESG------------------------------------GELVSKFSFAQDQ 4563
Query: 2161 TIADEPVVDLLKFLTNKLDAAVVKARLPSGHNPLQQLVLIIADGRFHEKDNLKRCVREAL 2220
T ++ K + N +D + + G L QL +II+DG + L++ VR A
Sbjct: 4564 T-------NVQKLVQNSID---IFQQQKLGGAELWQLQIIISDGICENHEVLRQLVRHAR 4613
Query: 2221 ASNRMVAFLLLD-----NSQESIMDLMEASF---EGGKM--KFSKYMDSFPFPYYIVLRN 2270
M+ F+++D + SI D+ +A + + G+M K KY+D+FPF +Y+++R+
Sbjct: 4614 ELKIMLVFVVIDALAAASGSSSITDIKQAKYISQDDGQMVLKMEKYLDTFPFEFYVIVRD 4673
Query: 2271 IEALPRTLANLLRQ 2284
I+ LP L+++LRQ
Sbjct: 4674 IKELPSVLSSVLRQ 4687
Score = 81.6 bits (200), Expect = 3e-13
Identities = 106/470 (22%), Positives = 201/470 (42%), Gaps = 53/470 (11%)
Query: 434 YAKSKSDHDAQQFKFKPRAFQIESIMELEIPALANSSATEAFSDW--KEFSYEEKSADNM 491
Y K KS D K + S AL T F+ W + EE++A +
Sbjct: 2903 YCKDKSVEDLSVEKTLSFVMDVVSKQGNSDTALVAYCCTTVFARWTLRRLRMEEQAA--I 2960
Query: 492 ESSEECEILDEEWKHLEESILDNVVLIHSQLFGSGDLVQAPGIFEISDEDRLHSFSESYK 551
ESS LDE EE +L +G++++ P + + D D H + +SY+
Sbjct: 2961 ESSGFSTNLDET---AEEEFAKLFPDYEIKLDDAGNVIK-PKVTK-QDVDYSH-WLKSYE 3014
Query: 552 L---GIN------LIKGAHSSN---LASLDAKLIPEHLFYLSIDYRRKFHSSSKSANRYN 599
G+ ++KGA + + + L+ H+ L D ++++ ++
Sbjct: 3015 RVFGGVEEPMSHVILKGAALATHGKVGHVMPSLLQAHVTVLETDCI----DVAEASPSFD 3070
Query: 600 FYKDSNAHEIEQMLKVLAPLRQQITSLLNEWEEQNDLQRFLDVIDMLLTLPSDIPLAKAF 659
FY+ +A E ++ + V L + + LL +W E + LQ+ + LL+ P+A+
Sbjct: 3071 FYRQHSAAETQKCVNVATKLLKFVNGLLAKWPEHDTLQQIAFQCNELLSFSVVTPVARLL 3130
Query: 660 SGLQFLLHKAQVMQENHSKFTFSNQLKSVFD-LMSSWHKMELGSWPVLLDEVMDQYENNA 718
+ ++ + ++ S+ + +F L+ SW ++EL WP L D +E A
Sbjct: 3131 AKVEQIYTFLHEWEKLASRDVSVREYIDIFTTLIVSWRRLELAMWPKLFD-----FEEEA 3185
Query: 719 KKSVLSSSIH--YF*SINFPKSNFYFSYESCS-----LEDFIQTSSFGEFRKRLQLLYAF 771
+K L Y + + N S + + L F+ S+ G++ RL+LL A
Sbjct: 3186 QKDGLGQWWFNVYEAVVVVCRDNSELSRDDITQLVQTLNLFLSQSTIGQYSFRLELLDAV 3245
Query: 772 LGQNHTSACLKINSSNIVFFLHCWTLQLLSDGAVNILVQYVWILCAVLTNHIDASRKEIL 831
L H + S N V A+ + Y + +T H+ A +K +
Sbjct: 3246 L--KHIGSMEPSTSVNQVTV------------ALKAFLVYYKMFVPSITAHVAARKKSLQ 3291
Query: 832 TELKDLVKLCRWEQDKSYSSIENLKKSRQKLKKLIKKHTDILQEPMDKLI 881
++++++ L W+ ++ E+ +KS +KL K++KK+ +L EP+ ++
Sbjct: 3292 KDIQEVILLASWKDTNVHALKESARKSHRKLFKVVKKYRTLLCEPVKSVL 3341
>emb|CAA20864.1| SPCC737.08 [Schizosaccharomyces pombe] gi|19075870|ref|NP_588370.1|
hypothetical protein SPCC737.08 [Schizosaccharomyces
pombe 972h-] gi|7490697|pir||T41581 hypothetical
coiled-coil protein - fission yeast (Schizosaccharomyces
pombe)
Length = 4717
Score = 281 bits (718), Expect = 2e-73
Identities = 244/872 (27%), Positives = 411/872 (46%), Gaps = 130/872 (14%)
Query: 1452 EQEESKEVPGNDNTGIEMDQD------FQADAVSLSEDS----SENEDCDGENEELESEM 1501
E ++ +E+ ++T + D D ++D +++DS +EN D + EN++L+ E+
Sbjct: 3929 EDDDLEELANEEDTANQSDLDESEARELESDMNGVTKDSVVSENENSDSEEENQDLDEEV 3988
Query: 1502 GPTGPD-SEAVGEKIWDQ-NEDETPDDTGEKYESGPSVKDGD-----GSNKELRAKDDST 1554
D S ++ EK+WD+ NE++ + + E + + D NK L KD
Sbjct: 3989 NDIPEDLSNSLNEKLWDEPNEEDLLETEQKSNEQSAANNESDLVSKEDDNKALEDKDRQE 4048
Query: 1555 SDQSGDDSCDEG--DAQNDEAAAQNEFDDEENGDDVNMDKEAAHSDATG-LKPDEPDHSS 1611
+ + S D G D + N EN D +++ ++ + G + D
Sbjct: 4049 KEDEEEMSDDVGIDDEIQPDIQENNSQPPPENEDHLDLPEDLKLDEKEGDVSKDSDLEDM 4108
Query: 1612 DMEIDLNANEDVDPIEEGDQEGHDDSAENGNQEDETCPPDEIMEEAHTEVDVSSEKDDLG 1671
DME E+ D ++ + +D E N DE D+ + A E D +D
Sbjct: 4109 DMEAADENKEEADAEKDEPMQDFEDPLEENNTLDEDIQQDDFSDLA--EDDEKMNEDGFE 4166
Query: 1672 QEHQENDDMNSMDPKNDTS-ESSDVVNPQVSNVDLASQSKSDLQTSGSENIASQSNLSNS 1730
+ QEN++ K+D E +V Q + +KS ++ ++ + +
Sbjct: 4167 ENVQENEESTEDGVKSDEELEQGEVPEDQAIDNHPKMDAKSTFASAEADEENTDKGIVGE 4226
Query: 1731 HHDFGNP--AVTGGFPSSDMSEMDINMSDSSNTGGFSKTQPKSHLPQHEHSFSQEKQTNP 1788
+ + G A G + ++ + + ++ G + T PK + + + +
Sbjct: 4227 NEELGEEDGAAESGVRGNGTADGEFSSAEQVQKGEDTST-PKEAMSEADRQY-------- 4277
Query: 1789 SRSTGDALDFRKE--KINVSGDLPEDNIEHHGEMDDNNADEYGYVSEFEKGTTQALGPAT 1846
+S GD L ++ +I+ DL E + DD+ E+ +V E E+ QALG A
Sbjct: 4278 -QSLGDHLREWQQANRIHEWEDLTESQSQ---AFDDS---EFMHVKEDEEEDLQALGNAE 4330
Query: 1847 LEQVDRNIDVDKVDTESRAGEDANLQLEKQNSEIDSVSNSSLLPKNEKRDQANMPVMEKS 1906
+Q+ ++ID D E N DS++++++ ++ D+ ++
Sbjct: 4331 KDQI-KSIDRD----------------ESANQNPDSMNSTNIA--EDEADEVGDKQLQDG 4371
Query: 1907 QDDGSVKPLGSANIDPESHLEDLISISRSYLGENTHKLSQLSVNDEELGKYHE-----PC 1961
QD +K G + E SI++S E +LS+ ++EL Y+ P
Sbjct: 4372 QDISDIKQTGEDTLPTEFG-----SINQS---EKVFELSEDEDIEDELPDYNVKITNLPA 4423
Query: 1962 DAPDHVKDNATALWRRYELSTTKLSQELTEQLRLVLEPTVASKLQGYYKTGKRIHMKKVI 2021
P D A LW ++E ST +LS EL EQLRL+LEPT+A+K+QG ++TGKR++MK++I
Sbjct: 4424 AMPI---DEARDLWNKHEDSTKQLSIELCEQLRLILEPTLATKMQGDFRTGKRLNMKRII 4480
Query: 2022 QFIASYYRMDKIWLRRTRPNKRDYQVVIAVDDSHSMSESCCGDVAVEALVTVCRAVSQLE 2081
+IAS ++ DKIW+RR +P+KR YQV+I++DDS SMSES +A+E L V +A+S LE
Sbjct: 4481 PYIASQFKKDKIWMRRVKPSKRTYQVMISIDDSKSMSESGSTVLALETLALVTKALSLLE 4540
Query: 2082 MGSLAVASFGTKGNINLLHDFDSPFTAESGVKVSRIYTSLVFFFIDISTVHLLNMLKGSD 2141
+G +AV FG + LLH FD F++ESGV
Sbjct: 4541 VGQIAVMKFGEQP--ELLHPFDKQFSSESGV----------------------------- 4569
Query: 2142 CSFLTEEQMVSNLTFKQENTIADEPVVDLLKFLTNKLDAAVVKARLPSGHNPLQQLVLII 2201
QM S+ TF+Q NT V L + K A ++ ++QL +II
Sbjct: 4570 -------QMFSHFTFEQSNT-----NVLALADASMKCFNYANTASHHRSNSDIRQLEIII 4617
Query: 2202 ADGRFHEKDNLKRCVREALASNRMVAFLLLDN----SQESIMDLMEASF---EGGKM--K 2252
+DG + D++++ +R A M+ F++LDN + SI+D+ + + E G M K
Sbjct: 4618 SDGICEDHDSIRKLLRRAQEEKVMIVFVILDNVNTQKKSSILDIKKVYYDTKEDGTMDLK 4677
Query: 2253 FSKYMDSFPFPYYIVLRNIEALPRTLANLLRQ 2284
Y+D F F YY+V+RNIE LP+ L++ LRQ
Sbjct: 4678 IQPYIDEFAFDYYLVVRNIEELPQLLSSALRQ 4709
Score = 78.6 bits (192), Expect = 2e-12
Identities = 69/293 (23%), Positives = 136/293 (45%), Gaps = 31/293 (10%)
Query: 598 YNFYKDSNAHEIEQMLKVLAPLRQQITSLLNEWEEQNDLQRFLDVIDMLLTLPSDIPLAK 657
YNFY D N + ++ ++ + + SL+ W E L+ D ID +L L P+A+
Sbjct: 3125 YNFYSDPNPSKAIEVRDLIKIVESRAISLIKNWPENFVLRGLKDAIDAILNLSPFSPIAE 3184
Query: 658 AFSGLQFLLHKAQVMQENHSK-FTFSNQLKSVFDLMSSWHKMELGSWPVLLDEVMDQYEN 716
S L+ + H ++ S+ ++ +N++ + + W K EL +W LL +++Y+
Sbjct: 3185 YLSKLERVFHLLSEWEKLASREYSLANEMDLIKKKIIDWRKFELSNWNNLLK--LEEYKL 3242
Query: 717 NAK-----KSVLSSSI--HYF*SINFPKSNFYFSYESCS-LEDFIQTSSFGEFRKRLQLL 768
+ + S+L I +F + F K N ES S + FI + GEF+ L+ L
Sbjct: 3243 SERVYPRLYSILQFIILKPFFENSKFTKQNL---CESASIIVQFITDLTVGEFQLCLKCL 3299
Query: 769 YAFLGQNHTSACLKINSSNIVFFLHCWTLQLLSDGAVNILVQYVWILCAVLTNHIDASRK 828
+F + +A L+I H LL+ + Y + ++ I ++
Sbjct: 3300 LSF---SQHAASLRI--------CHGIDAMLLN------IYHYFEQFLSKVSEAIHTQKQ 3342
Query: 829 EILTELKDLVKLCRWEQDKSYSSIENLKKSRQKLKKLIKKHTDILQEPMDKLI 881
+ +K+ + L W+ Y+ E+ KKS +L K++ ++ ++L++P+ +
Sbjct: 3343 SLENSIKERILLMSWKDTNVYALKESAKKSHAELFKVLHRYREVLRQPVSSYL 3395
>gb|EAA77856.1| hypothetical protein FG07258.1 [Gibberella zeae PH-1]
gi|46125761|ref|XP_387434.1| hypothetical protein
FG07258.1 [Gibberella zeae PH-1]
Length = 4911
Score = 280 bits (717), Expect = 3e-73
Identities = 234/907 (25%), Positives = 412/907 (44%), Gaps = 152/907 (16%)
Query: 1444 LSMMQKKEEQEESKEVPGNDNTGIEMDQDFQADAVSLS-----EDSSENEDCDGENEELE 1498
LS + ++ +EE+ E+ + D++ + D S+ E+ S+N D + E +++
Sbjct: 4082 LSELAQEANKEENGEMEDEKDAVDMADEELEGDMGSVDGAEDDEEGSKNGDEEEEENDMD 4141
Query: 1499 SEMGPTGP-DSEAVGEKIWDQNEDETPDDTGEKYESGPSVKDGDGSNKELRAKDDSTSDQ 1557
E G D AV EK+WD +++E EK + G K G + E A D+ Q
Sbjct: 4142 EEAGDVDDLDPTAVDEKMWDGDDEEK----AEKDQQGEKAK-GQKKDDEQLAGDEDAQKQ 4196
Query: 1558 SGDDSCD-----EGDAQNDEAAAQNEFDDEENGDDVNMDKEAAHSDATGLKP-------- 1604
G++ D E DA+ +E A E +D + +++N ++ A + T P
Sbjct: 4197 DGEEQPDVDDSGEQDAEEEEDEAGVEEEDVKTQEEMNKQEQTAQENDTLALPEDMDLDLG 4256
Query: 1605 ---------DEPDHSSDMEIDLNANEDVDPIEEGDQEGHDDSAEN----------GNQED 1645
D+ D SD+E + ED + ++GD++ D +AE G +ED
Sbjct: 4257 DEQEPASDSDDLDDLSDIEEEKKDVEDQEMGDDGDEDSDDAAAETQLQEEAGEEAGIEED 4316
Query: 1646 ETCPPDEIMEEAHTEVDVSSEKDDLGQEHQENDDMNSMDPKNDTSESSDVVNPQVSNVDL 1705
E P ++ + + +V E+++ +E ++ D N N T+++ +
Sbjct: 4317 EETPEEKAGGKDEVDEEVEPEEEEKAEEQEDATDQNQPPQDNATTDTDNA---------- 4366
Query: 1706 ASQSKSDLQTSGSENIASQSNLSNSHHDFGNPAVTGGFPSSDMSEMDINMSDSS-NTGGF 1764
+ SD++TSG + A ++ ++ G +M E + S+ N G
Sbjct: 4367 ---APSDVKTSGQDQNADSMDVDDNFQSNAAQQEDG-----EMGEGAADQDTSAGNKGST 4418
Query: 1765 SKTQPKSHLPQHEHSFSQEKQTNPSRSTGDALD-FRKEKINVSGDLPEDNIEHHGEMD-- 1821
S+++ + E +++P + GDAL+ + +++ ++ D E + D
Sbjct: 4419 SQSKEITDRADQEQDKPDSARSDPFKKLGDALERWHRQQKDIKDAESSDANEQNAPQDPS 4478
Query: 1822 -DNNADEYGYVSEFEKGT-TQALGPATLEQVD-----RNIDVDKVDTESRAGEDANLQLE 1874
D E+ ++ + E T TQA+G A EQV ID +K D SR ++ + E
Sbjct: 4479 ADQGRKEFQHLQDDETATDTQAMGTADDEQVQPIDESMAIDEEKQDPTSRLMDEDKEETE 4538
Query: 1875 KQNSEIDSVSNSSLLPKNEKRDQANMPVMEKSQDDGSVKPLGSANIDPE--------SHL 1926
+ ++D+ + E D +N + D S N D E L
Sbjct: 4539 QDPDQMDTADTA------EAPDASNQDADKDQDDTRSGVKTRQGNYDRELSPSEQEAQML 4592
Query: 1927 EDLISISRSYLGENTHKLSQLSVNDEELGKYHEPCDAPDHVKDNATALWRRYELSTTKLS 1986
E+ + + E + +LS ++DEE P + W ++ T LS
Sbjct: 4593 EE--DQDEADIQETSTQLSITHISDEE---------RPLRDFGESMQQWTEFQTKTHSLS 4641
Query: 1987 QELTEQLRLVLEPTVASKLQGYYKTGKRIHMKKVIQFIASYYRMDKIWLRRTRPNKRDYQ 2046
LT QLRL+L P+ ++KL G ++TGKR+ +K++I +IAS Y+ DKIW+RR+ P KR YQ
Sbjct: 4642 LSLTSQLRLILTPSQSTKLSGGFRTGKRLSIKRIIPYIASSYKRDKIWMRRSIPTKRTYQ 4701
Query: 2047 VVIAVDDSHSMSESCCGDVAVEALVTVCRAVSQLEMGSLAVASFGTKGNINLLHDFDSPF 2106
+++ VDDS SM E+ G +A+E+LV V R+++ LE G + V FG ++ H PF
Sbjct: 4702 ILLCVDDSKSMGETSSGTLAMESLVMVSRSLTMLEAGQVGVMGFG--ADVFAAHCLTEPF 4759
Query: 2107 TAESGVKVSRIYTSLVFFFIDISTVHLLNMLKGSDCSFLTEEQMVSNLTFKQENTIADEP 2166
+++G KV + F Q+ T
Sbjct: 4760 ASDAGAKV------------------------------------LQKFNFSQDRT----- 4778
Query: 2167 VVDLLKFLTNKLDAAVVKARLPSGHNPLQQLVLIIADGRFHEK--DNLKRCVREALASNR 2224
D+ + ++ + SG+ L QL LI++DG + ++R +REA+
Sbjct: 4779 --DIGLLIQRTIETFREARQQSSGNTDLWQLALILSDGLTPSSAHEGIRRMLREAMEERI 4836
Query: 2225 MVAFLLLDNS----QESIMDLMEASF--EGGKMK--FSKYMDSFPFPYYIVLRNIEALPR 2276
M+ F+++D++ +S+++L EA F +GG+ K +Y+D+FPF YY+++ N+E LP
Sbjct: 4837 MIVFIIMDDTGKKKGDSVLELKEAKFVRDGGESKVVIERYLDTFPFQYYLIVHNLEELPS 4896
Query: 2277 TLANLLR 2283
LA LLR
Sbjct: 4897 ALAGLLR 4903
Score = 68.2 bits (165), Expect = 3e-09
Identities = 97/430 (22%), Positives = 176/430 (40%), Gaps = 51/430 (11%)
Query: 561 HSSNLASLDAKLIPEHLFYLSIDYRRKFHSSSKSANRYNFYKDSNAHEIEQMLKVLAPLR 620
H + +L +K++ +F+L+ D S + YNFY D+N E Q++ ++ ++
Sbjct: 3221 HKNIDRNLTSKMLAGTMFFLN-DKLESLISPTVDKG-YNFYTDANVPEARQLVALMYKIK 3278
Query: 621 QQITSLLNEWEEQNDLQRFLDVI---DMLLTLPSDIPLAKAFSGLQFLLHKAQVMQ---- 673
+ L +E +Q DVI D +L L PLAK +++L Q
Sbjct: 3279 ARFREL-QMVDEIGHMQPLADVIQACDQVLELVHSEPLAKILPKVEYLHGHVYEWQFGGW 3337
Query: 674 --ENHSKFTFSNQLKSVFDLMSSWHKMELGSWPVLLDEVMDQYENNAK-------KSVLS 724
+ + T N L D + W ++EL +W L D + +++A + V++
Sbjct: 3338 ASKIYGVLTLHNLLT---DTVIRWRRLELSTWANLFDMEQKKCQDDAYSWWFVAYQVVIA 3394
Query: 725 SSIHYF*SINFPKS-NFYFSYESCSLEDFIQTSSFGEFRKRLQLLYAFLGQNHTSACLKI 783
+ ++ PK Y + SLE + T+ G++ RL LL Q+H LK+
Sbjct: 3395 VPLSL---VDVPKEMEEYAASLISSLEMYFSTAIVGQYGARLALLRQL--QSH----LKL 3445
Query: 784 NSSNIVFFLHCWTLQLLSDGAVNILVQYVWILCAVLTNHIDASRKEILTELKDLVKLCRW 843
+ + LQ++ N +QY ++ + R I ++KD++ + W
Sbjct: 3446 LTEDYP------VLQVILHSLSNF-IQYYSRYEKIMEETLQKGRLPIEKKMKDVLLMASW 3498
Query: 844 EQDKSYSSIENLKKSRQKLKKLIKKHTDILQEPMDKLI------RDVLHKGSISGVSDLP 897
+ + E+ +KS QKL ++I+K +L + ++I DV I S P
Sbjct: 3499 KDTNINALRESARKSHQKLFRIIRKFRGVLGQQAKQIIEQGLPDEDVRRMAHIDNKSPAP 3558
Query: 898 -----LFSDENRLYQEGWKDVWHMIENIYIKAVDSGNIWKEDKNNQRKSRALSDLLNLLK 952
+FS N GW D + N+ I + + + D ++ L
Sbjct: 3559 EVPADVFSKLNET-MPGWIDGHKRLANVSKTVSVMRKISDNPDMSSDVPQTIDDYVSSLS 3617
Query: 953 TSGLSQRKST 962
S + RK T
Sbjct: 3618 ESMVELRKET 3627
>gb|AAS54563.1| AGR074Cp [Ashbya gossypii ATCC 10895] gi|45201169|ref|NP_986739.1|
AGR074Cp [Eremothecium gossypii]
Length = 4899
Score = 279 bits (713), Expect = 9e-73
Identities = 217/863 (25%), Positives = 421/863 (48%), Gaps = 96/863 (11%)
Query: 1449 KKEEQEESKEVPGNDNTGIEMDQDFQADAVSL-SEDSSENEDCDGENEELESEMGPTGPD 1507
+K++ E S++ D+ ++M+ D + + +DS + ++ + E ++L+ E+ D
Sbjct: 4098 QKDQDERSED---EDDNAVDMEGDIAGELENAPGQDSGDEDEMEEEEKDLDEEIDDLDDD 4154
Query: 1508 SEAVGEKIWDQN-EDETPDDTGEKYESGPSVKDGDGSNKE-LRAKDDSTSDQSGDDSCDE 1565
A+ +K+W++ E++T + EK + D S +E A D++ +D + +D +E
Sbjct: 4155 PNAIDDKMWNEEPEEDTKEKESEKMPENSAADDVQASKEEDENANDNNQADGTAEDGREE 4214
Query: 1566 GDAQNDEAAAQNEFDDE-ENGDDVNMDKEAAHSDATGLKPD---------EPDHSSDMEI 1615
DA+ D E DDE ++ D+ +++ + L D + D +D +
Sbjct: 4215 DDAEEDGEEDVGEQDDEVKHEDNEDLEANVPEVETMDLPEDMNLDSGDEKDSDDGADDQF 4274
Query: 1616 DLNANEDVDPIEEGDQEGHDDSAENGNQ--EDETCPPDEIMEEAHTEVDVSSEKDDLGQ- 1672
D + + D +P E + E DD+ + N +DE P+E ++ D + D+
Sbjct: 4275 DDDMSVDEEPNAE-EMETKDDAIDENNMGSDDEALSPEEEQQDDGIAEDGEAASDEEADG 4333
Query: 1673 EHQENDDMNSMDPKNDTSESSDVVNPQVSNVDLASQSKSDLQTSGSENIASQSNLSNSHH 1732
+E D NS D + + +D + ++ + AS + L+ G E++A ++
Sbjct: 4334 AEEEGQDQNSEDELAE--DHADENKQEPADQEAASDKQQGLE--GIEDLADVQDIDMEAA 4389
Query: 1733 DFGNPAVTG-GFPSSDMSEMDINMSDSSNTGGFSKTQPKSHLPQHEHSFSQEKQTNPSRS 1791
+ +G G ++D E D N+ S + Q Q S+E+ +
Sbjct: 4390 VEQHAGASGEGAEAADSKEQD-NVGSSGMAQSHEQQQDNGEEVQDS---SREEAIESLKQ 4445
Query: 1792 TGDALDFRKEKINVSGDLPEDNIEHHGEMDDNNADEYGYVS-EFEKGTTQALGPATLEQV 1850
GD+L + + + E + + + DE+ +++ TQAL AT +Q+
Sbjct: 4446 LGDSLKEFHRRHQQIKEASNNEEETNADAANTRPDEFEHINGAATDADTQALDTATKDQL 4505
Query: 1851 DRNIDVDKVDTESRAGEDANLQLEKQ--NSEIDSVSNSSLLPKNEKRDQANMPVMEKSQD 1908
+ VD + +D ++ +K+ +++ID++ + + D A + + +
Sbjct: 4506 E------SVDKDQAIEDDHDMDADKKAPDADIDAMD----VDDADADDDAQLQNGDVDAE 4555
Query: 1909 DGSVKPLGSANIDPESHLEDLISISRSYLGENTHKLSQLSVNDEELGKYHEPCDAPDHVK 1968
+ + K +G + + ++ ++ + +L Q+ + + + P
Sbjct: 4556 EVNGKNVGGFIGNRDMQDDNAQALDLDLPLQQQDELEQIIEQIDIESRADQEAAVPPRSI 4615
Query: 1969 DNATALWRRYELSTTKLSQELTEQLRLVLEPTVASKLQGYYKTGKRIHMKKVIQFIASYY 2028
+++ LW++ E +T +L L+EQLRL+LEPT+A+KL+G YKTGKR++MK++I +IAS +
Sbjct: 4616 EDSRVLWKKSEQATDELVTVLSEQLRLILEPTLATKLRGDYKTGKRLNMKRIIPYIASQF 4675
Query: 2029 RMDKIWLRRTRPNKRDYQVVIAVDDSHSMSESCCGDVAVEALVTVCRAVSQLEMGSLAVA 2088
R DKIWLRRT+P+KR YQ++IAVDDS SMSES ++A +++ V +A++QLE G L++
Sbjct: 4676 RKDKIWLRRTKPSKRQYQIMIAVDDSKSMSESKSVELAFQSICLVSKALTQLESGGLSIV 4735
Query: 2089 SFGTKGNINLLHDFDSPFTAESGVKVSRIYTSLVFFFIDISTVHLLNMLKGSDCSFLTEE 2148
FG LH+FD F A++G KV + +
Sbjct: 4736 KFGE--TTKELHNFDQQFAADAGAKVFQWF------------------------------ 4763
Query: 2149 QMVSNLTFKQENTIADEPVVDLLKFLTNKLDAAVVKARLPSGHNPLQQLVLIIADGRFHE 2208
F++ T V + +K + + S ++ L QL ++I+DG +
Sbjct: 4764 ------GFQETKTDVKRLVAESIK---------IFERARTSQNSDLWQLQIVISDGVCED 4808
Query: 2209 KDNLKRCVREALASNRMVAFLLLD--NSQESIMDLMEASF---EGG--KMKFSKYMDSFP 2261
+ ++R VR A + M+ F+++D N++ESI+D+ + S+ + G +++ +KY+D+FP
Sbjct: 4809 HETVQRLVRRARENRIMLVFVIIDGINAKESILDMGQVSYVPDQNGVLQLQVTKYLDTFP 4868
Query: 2262 FPYYIVLRNIEALPRTLANLLRQ 2284
F +Y+V+R+I LP ++ +LRQ
Sbjct: 4869 FEFYVVVRDISELPEMISIILRQ 4891
Score = 78.2 bits (191), Expect = 3e-12
Identities = 70/299 (23%), Positives = 141/299 (46%), Gaps = 31/299 (10%)
Query: 595 ANRYNFYKDSNAHEIEQMLKVLAPLRQQITSLLNEWEEQNDLQRFLDVIDMLLTLPSDIP 654
A+ +FY + E+++ K++ L + +LL +W E L+ + L ++ P
Sbjct: 3282 ASDIDFYHGGSVVELKKSAKLIERLLYSVNNLLVQWPEHATLRELFRICKEYLEYSANTP 3341
Query: 655 LAKAFSGLQFLLHKAQVMQENHSK-FTFSNQLKSVFDLMSSWHKMELGSWPVLLDEVMDQ 713
+AK ++ + A ++ SK + S + + L+ W K+EL +W L +
Sbjct: 3342 IAKLLQKIEQIYTFAAEWEKYASKNVSLSVHIDELTRLIVEWRKLELLTWKSLFE----- 3396
Query: 714 YENNA-KKSVLSSSIHYF*SI---NFPKSNFYFSYES-----CSLEDFIQTSSFGEFRKR 764
YEN + ++++ + H + +I NF F+ + E +L F S++GE R
Sbjct: 3397 YENKSVERNIGNWWFHLYETIINANFKNVEFHGTDEEYTQLLLALNVFFSKSTYGEIHIR 3456
Query: 765 LQLLYAFLGQNHTSACLKINSSNIVFFLHCWTLQLLSDGAVNILVQYVWILCAVLTNHID 824
LQ+++AF+ H S +NS+ LH T NI Y L V+ + I
Sbjct: 3457 LQMVHAFI--KHVSV---LNSAGTPV-LHALT---------NITTFYEQFL-PVIEDSIA 3500
Query: 825 ASRKEILTELKDLVKLCRWEQDKSYSSIENLKKSRQKLKKLIKKHTDILQEPMDKLIRD 883
A++K + E+ +++ L W+ + ++ ++S L K+++K+ D+L + L+++
Sbjct: 3501 ANKKILEKEISEVILLASWKDVNVDALKQSSRRSHNNLYKILRKYRDVLATEVSPLVQN 3559
Score = 68.6 bits (166), Expect = 3e-09
Identities = 83/428 (19%), Positives = 172/428 (39%), Gaps = 59/428 (13%)
Query: 1523 TPDDTGEKYESGPSVKDGDGSNKELRAKDDSTSDQSGDDSCDEGDAQNDEAAAQNEFDDE 1582
+P+ E+ E ++ +G G A+++S + +D ++ ND+ Q+E ++
Sbjct: 4049 SPEPPSEEVEDN-NLHEGTGLGDGEGAQNNSKDVEEDEDLLEDAQKPNDDQKDQDERSED 4107
Query: 1583 ENGDDVNMDKEAAHS--DATGLKPDEPDHSSDMEIDLNANEDVDPIEEGDQEGHDDSAEN 1640
E+ + V+M+ + A +A G + D + E DL+ E++D +++ D DD N
Sbjct: 4108 EDDNAVDMEGDIAGELENAPGQDSGDEDEMEEEEKDLD--EEIDDLDD-DPNAIDDKMWN 4164
Query: 1641 GNQEDETCPPDEIMEEAHTEVDVSSEKDDLGQEHQENDDMNSMDPKNDTSESSDVVNPQV 1700
E++T E+ ++ +S DD+ +E+++ N + + T+E
Sbjct: 4165 EEPEEDT------KEKESEKMPENSAADDVQASKEEDENANDNNQADGTAED-------- 4210
Query: 1701 SNVDLASQSKSDLQTSGSENIASQSNLSNSHHDFGNPAVTGGFPSSDM----SEMDINMS 1756
+ + D + G E++ Q + H D N + P + +M+++
Sbjct: 4211 ------GREEDDAEEDGEEDVGEQDD-EVKHED--NEDLEANVPEVETMDLPEDMNLDSG 4261
Query: 1757 DSSNTGGFSKTQPKSHLPQHEHSFSQEKQTNPSRSTGDALDFRKEKINVSGDLPEDNIEH 1816
D ++ + Q + E ++E +T + + E ++ + +D I
Sbjct: 4262 DEKDSDDGADDQFDDDMSVDEEPNAEEMETKDDAIDENNMGSDDEALSPEEEQQDDGIAE 4321
Query: 1817 HGE--------------MDDNNADEYGYVSEFEKGTTQALGPAT------LEQVDRNIDV 1856
GE D N+ DE E A A LE ++ DV
Sbjct: 4322 DGEAASDEEADGAEEEGQDQNSEDELAEDHADENKQEPADQEAASDKQQGLEGIEDLADV 4381
Query: 1857 DKVDTESRAGEDANLQLE----KQNSEIDSVSNSSLLPKNEKRDQANMPVMEKSQDDG-- 1910
+D E+ + A E + E D+V +S + +E++ V + S+++
Sbjct: 4382 QDIDMEAAVEQHAGASGEGAEAADSKEQDNVGSSGMAQSHEQQQDNGEEVQDSSREEAIE 4441
Query: 1911 SVKPLGSA 1918
S+K LG +
Sbjct: 4442 SLKQLGDS 4449
>ref|XP_615168.1| PREDICTED: similar to Midasin (MIDAS-containing protein), partial
[Bos taurus]
Length = 1914
Score = 278 bits (710), Expect = 2e-72
Identities = 256/952 (26%), Positives = 428/952 (44%), Gaps = 169/952 (17%)
Query: 1450 KEEQEESKEVPGNDNTGIEMDQDFQADAVS--LSEDSSENEDCDGENEELESEMGP-TGP 1506
KE+ + ++ G DN IEM +DF L E ++E D E +L+ +MG G
Sbjct: 1004 KEDPDSKSDIKGEDNA-IEMSEDFDGKMHDGELEEQEEDDEKSDSETGDLDKQMGDLNGE 1062
Query: 1507 DSEAVGEKIWDQNEDETPDDTGEKYE-SGPSVKDGDG-------------SNKELRAKDD 1552
+++ + E++W ++DE ++ K E +GP + + D SN+E + + D
Sbjct: 1063 EADKLDERLWGDDDDEEDEEEDSKTEETGPGMDEEDSELVAKDDNLDAGKSNRE-KTRQD 1121
Query: 1553 STSDQSGDDSCDEGDAQN--DEAAAQNEFDDEE----NGDDVNMDKEAAHSDATGLKPDE 1606
++ ++ D+G Q+ +E + E+D+ E +G++ + + A L D
Sbjct: 1122 KKEEKEEAEADDDGRGQDKINEQIDEREYDENEVDPYHGNEEKLPEPEALDLPDDLNLDS 1181
Query: 1607 PDHSSDMEIDLNANEDVDPIE------EGDQEGHDDSAENGNQEDETCPP---------- 1650
D D + D E+ +P+E + ++ GH+ AE+ N+E E
Sbjct: 1182 EDKDGDGDTDHEDGEEENPLEIKEQPKDTEEAGHE--AEDINEETEADQDEGQAQPQPEG 1239
Query: 1651 ----DEIMEEAHTEVDVSSEKDDL-GQEHQENDD----MNSMDPKNDTSESS-DVVNPQV 1700
D+ EE E+D ++ D EH E D ++S D DTSE S + P
Sbjct: 1240 GHSEDDKGEEGEEEMDTGADDGDQDAAEHPEEDTEEAPLSSEDKDKDTSEESPEKDTPLD 1299
Query: 1701 SNVDLASQSKSDLQTSGSENIASQSNLSNSHHDFGNPAV-----------TGGFPSSDMS 1749
+ +Q K + ++S E + H G + G P +
Sbjct: 1300 QGLQPQTQEKEEGESSDMEEPVPEPTERKEHESCGQTGLESVQSEQAVELAGAAPEKEQG 1359
Query: 1750 E-------MDINMSDSSNTGGFSKTQPKSHLPQHEHSFSQEK-QTNPSRSTGD---ALDF 1798
D N ++ + ++ + H ++ SF ++ Q + RS GD +
Sbjct: 1360 REEHGSGAADANQAEGHESSFMARMASQKHTRKNTQSFKRKPGQADNERSLGDHSERVHK 1419
Query: 1799 RKEKINVSGDLPEDNIEHHGEMDDNNADEYGYVSEFEKGTTQALGP-------------- 1844
R ++ +D + + +D A E+ E Q G
Sbjct: 1420 RLRTMDTESRAEQDPAQPQAQAEDAEAFEH-IKQGSEPYDAQTYGTELGALPRSSSSVSA 1478
Query: 1845 -----ATLEQVDRNIDVDKVDTESRAGEDANLQLEKQNSEIDSVSNSSLLPKNEKRDQAN 1899
A+ EQ D K E ED ++ E+Q E+ +V L P+ K
Sbjct: 1479 YADYVASTEQQQSAKDSSKAHEEEEV-EDTSVDPEEQE-ELRAVDTEPLKPEEVKSGSTA 1536
Query: 1900 MPVME---------KSQDDGSVKPLGS----ANIDPESHLEDLISISRSYLGENTHKLSQ 1946
P E K+++D + S N PE + I + L + +
Sbjct: 1537 QPGSEEMEMETQTVKTEEDQHPRTDPSHEETENEKPERSRDSTIHTAHQLLVDTIFQPFL 1596
Query: 1947 LSVND--EELGKYHE---PCDAPDHVKDNATA-LWRRYELSTTKLSQELTEQLRLVLEPT 2000
VN+ +EL + E P ++ + ++ A A +W+ Y + T LSQ+L EQLRL+LEPT
Sbjct: 1597 KDVNELRQELERQLETWQPHESGNPEEEKAAAEMWQSYLVLTAPLSQQLCEQLRLILEPT 1656
Query: 2001 VASKLQGYYKTGKRIHMKKVIQFIASYYRMDKIWLRRTRPNKRDYQVVIAVDDSHSMSES 2060
A+KL+G Y+TGKR++M+KVI +IAS +R DKIWLRRT+P+KR YQ+ +A+DDS SM ++
Sbjct: 1657 QAAKLKGDYRTGKRLNMRKVIPYIASQFRKDKIWLRRTKPSKRQYQICLAIDDSSSMVDN 1716
Query: 2061 CCGDVAVEALVTVCRAVSQLEMGSLAVASFGTKGNINLLHDFDSPFTAESGVKVSRIYTS 2120
+A E+L + A++ LE+G +AV SFG ++ LLH F F+ SG ++ R+
Sbjct: 1717 HTKQLAFESLAVIGNALTLLEVGQIAVCSFGE--SVKLLHPFHEQFSDYSGSQILRL--- 1771
Query: 2121 LVFFFIDISTVHLLNMLKGSDCSFLTEEQMVSNLTFKQENTIADEPVVDLLKFLTNKLDA 2180
F+Q+ T + L+ + N A
Sbjct: 1772 ---------------------------------CKFQQKKT----KIAQFLESVANMFAA 1794
Query: 2181 AVVKARLPSGHNP-LQQLVLIIADGR---FHEKDNLKRCVREALASNRMVAFLLLDN--S 2234
A +L +P + QL+L+++DGR KD + V+ A +N V F++LDN S
Sbjct: 1795 A---QQLSQNVSPEIAQLLLVVSDGRGLFLEGKDRVLAAVQAARNANIFVIFVVLDNPSS 1851
Query: 2235 QESIMDLMEASFEG-GKM-KFSKYMDSFPFPYYIVLRNIEALPRTLANLLRQ 2284
++SI+D+ F+G G+M + YM+ FPFP+YI+LR++ ALP TL++ LRQ
Sbjct: 1852 RDSILDIKVPIFKGPGEMPEIRSYMEEFPFPFYIILRDVNALPETLSDALRQ 1903
Score = 89.7 bits (221), Expect = 1e-15
Identities = 109/484 (22%), Positives = 183/484 (37%), Gaps = 76/484 (15%)
Query: 423 EFASLWMSMKVYAKSKSDHDAQQFKFKPRAFQIESIMELEIPALANSSATEAFSDWKEFS 482
E + W + A+ K++ ++ ++++ R + E E S D+ +
Sbjct: 1 EIINEWDEQERIAQEKAEQESSLYRYRGRTPRTALSEEEEEERAFRSQFPLHEKDFADIL 60
Query: 483 YEEKSADNMESSEECEILDEEWKHLEESILDNVVLIHSQL-FGSGDLV---QAPGIFEIS 538
E + S + E L +S + V+ IH QL G + Q+P
Sbjct: 61 VEPTLEEKGPSGGQEEEATPGPAVLSQSSMQAVMRIHQQLCLGFARSLWYQQSPPPH--G 118
Query: 539 DEDRLHSFSESYKLGINLIKGAHSSNLASLDAKLIPEHLFYLSIDYRRKFHSSS-----K 593
E L F Y+ G +L+ + L+ +L+ L ++ + F + K
Sbjct: 119 TEHYLSLFLSCYQTGASLVTHFYPLMGVELNDQLLGSQLLACTLSHNTLFGEVTSDLMVK 178
Query: 594 SANRYNFYKDSNAHEIEQMLKVLAPLRQQITSLLNEWEEQNDLQRFLDVIDMLLTLPSDI 653
Y+FY N E VL Q + L V+D + + P
Sbjct: 179 PDGPYDFYHHPNIPEARHCQPVL----------------QGFSEALLVVMDRICSFPLSS 222
Query: 654 PLAKAFSGLQFLLHKAQVMQENHSK-FTFSNQLKSVFDLMSSWHKMELGSWPVLLDEVMD 712
P++K +GL+ LL KAQ +EN S+ + L V L+ W K+EL W + LD M
Sbjct: 223 PISKFLNGLEILLAKAQDWEENASRALSLRKHLDLVSQLIIRWRKLELNCWSMSLDNTMK 282
Query: 713 QYENNAKKSVLSSSIHYF*SINFPKSNFYFSYES-------------CSLEDFIQTSSFG 759
++ + K H+F + + E +L+ FI+ SS G
Sbjct: 283 RHTEKSTK-------HWFSIYQMLEKHMQEQTEEQEDDKQMTLMLLVSTLQAFIEGSSLG 335
Query: 760 EFRKRLQLLYAFLGQNHTSACLKINSSNIVFFLHCWTLQLLSDGAVNILVQYVWILCAVL 819
EF RLQ+L F HC L + + L +W L
Sbjct: 336 EFHIRLQMLLVF---------------------HCHVLLMPQVEGKDALCSVLWNLYHYY 374
Query: 820 T---NHIDAS----RKEILTELKDLVKLCRWEQDKSYSSIENLKKSRQKLKKLIKKHTDI 872
N + A R + ELK+ VK+ +W +S ++++K+ + L K +KK +
Sbjct: 375 KQFFNRVQAKIVELRSPLEKELKEFVKISKWNDVSFWSIKQSVEKTHRTLFKFMKKFEAV 434
Query: 873 LQEP 876
L EP
Sbjct: 435 LSEP 438
Score = 48.9 bits (115), Expect = 0.002
Identities = 100/456 (21%), Positives = 173/456 (37%), Gaps = 54/456 (11%)
Query: 1480 LSEDSSENEDCDGENEELESEMGPTGPDSEAVGEK-IWDQNEDETPDDTGEKYESGPSVK 1538
L ++ E+ +G E + E G G E G K + DQ E+E + + ++ G
Sbjct: 949 LPKEFMEDSAGEGATEFHDYEGGGIG---EGEGMKDVSDQIENE--EQAEDTFQKGQEKD 1003
Query: 1539 DGDGSNKELRAKDDSTSDQSGDDSCDEGDAQNDEAAAQNEFDDEENGDDVNMDKEAAHSD 1598
D +K +D+ + S D D + +E +E D E GD +DK+ D
Sbjct: 1004 KEDPDSKSDIKGEDNAIEMSEDFDGKMHDGELEEQEEDDEKSDSETGD---LDKQM--GD 1058
Query: 1599 ATGLKPD--------EPDHSSDMEIDLNANEDVDPIEEGDQE--GHDDSAENGNQEDETC 1648
G + D + D D E D E ++E D E DD+ + G E
Sbjct: 1059 LNGEEADKLDERLWGDDDDEEDEEEDSKTEETGPGMDEEDSELVAKDDNLDAGKSNREKT 1118
Query: 1649 PPDEIMEEAHTEVDVSSE-KDDLGQEHQEND-DMNSMDPKNDTSESSDVVNPQVSNVDLA 1706
D+ E+ E D +D + ++ E + D N +DP + E P+ +DL
Sbjct: 1119 RQDKKEEKEEAEADDDGRGQDKINEQIDEREYDENEVDPYHGNEEKL----PEPEALDLP 1174
Query: 1707 SQSKSDLQTSGSENIASQSNLSNSHHDFGNPAVTGGFPSSDMSEM-----DIN-MSDSSN 1760
D SE+ + + + NP P D E DIN +++
Sbjct: 1175 DDLNLD-----SEDKDGDGDTDHEDGEEENPLEIKEQP-KDTEEAGHEAEDINEETEADQ 1228
Query: 1761 TGGFSKTQPKSHLPQHEHSFSQEKQTNPSRSTGDALDFRKEKINVSGDLPEDNIEHHGEM 1820
G ++ QP+ + + E++ + GD + + ED E
Sbjct: 1229 DEGQAQPQPEGGHSEDDKGEEGEEEMDTGADDGDQ--------DAAEHPEEDTEEAPLSS 1280
Query: 1821 DDNNADEYGYVSEFEKGTTQALGPATLEQVD-RNIDVDK---VDTESRAGED-ANLQLEK 1875
+D + D E + Q L P T E+ + + D+++ TE + E LE
Sbjct: 1281 EDKDKDTSEESPEKDTPLDQGLQPQTQEKEEGESSDMEEPVPEPTERKEHESCGQTGLES 1340
Query: 1876 QNSEIDSVSNSSLLPKNEK-RDQANMPVMEKSQDDG 1910
SE +V + P+ E+ R++ + +Q +G
Sbjct: 1341 VQSE-QAVELAGAAPEKEQGREEHGSGAADANQAEG 1375
>ref|XP_419835.1| PREDICTED: similar to Midasin (MIDAS-containing protein) [Gallus
gallus]
Length = 5681
Score = 275 bits (704), Expect = 1e-71
Identities = 250/939 (26%), Positives = 421/939 (44%), Gaps = 181/939 (19%)
Query: 1448 QKKEEQEESKEVPGNDNTGIEMDQDFQADAVSLSEDS----------------------- 1484
++KE+Q+ ++ G DN IEM +DF+ ++
Sbjct: 4811 KEKEDQDSKPDIEGEDNA-IEMSEDFEGKMHDGEQEKKVIQKVAVLALQTLYLLCTETYP 4869
Query: 1485 ---SENEDCDGENEELESEMGP--TGPDSEAVGEKIWDQNEDETPDD--TGEKYESGPSV 1537
+EN++ E EEL+ +MG + + E++W ED+ D+ + + E+GP +
Sbjct: 4870 ELYTENDEKSDEEEELDKQMGDLDNAEADDKLDERLWGDEEDDDDDEDASSKAEETGPGM 4929
Query: 1538 KDGDGSNKELRAKDDSTSDQSGDDSCDEGDAQNDEAAAQNEFDDEENGDDVNMDKEAAHS 1597
+ D EL AKDD+ G + D + +N+ +D EN + ++ +
Sbjct: 4930 DEEDS---ELVAKDDNL----GTGNKDNKKQPPKDEETENQTEDNENKEKIHEQIDEREY 4982
Query: 1598 DATGLKPDEPDHSSDMEIDL-----NANEDVDPIEEGDQEGHDDSAENGNQEDETCPPDE 1652
D + P E++ N N + D +G++EG ++ EN + DE P +
Sbjct: 4983 DENEVDPYHGQQEKQPEVEPLDLPDNLNLEDDEKSDGEKEGEEEE-ENAFEIDEK--PVD 5039
Query: 1653 IME---------EAHTEVDVSSEKDDLGQEHQENDDMNSMD----PKN------DTSESS 1693
+ E E ++E + + + +E +E + + D P+N +
Sbjct: 5040 LNEAENTEGQNEENNSEAEGGDKDAEPAEEEEEEKGIPAADQGLQPQNVQIKPISFQQEE 5099
Query: 1694 DVVNPQVSNVDLASQSKSDLQT---SGSENIASQSNLS---------NSHHDFGNPAVTG 1741
D NP++ S+ + + +T +G EN+ S S + S ++G+ A +
Sbjct: 5100 DKDNPEMDEQVPESEERMEHETQGQTGQENLQSDSAVELAGEASERDQSKEEYGSGAASA 5159
Query: 1742 ----GFPSSDMSEMDINMSDSSNTGGFSKTQPKSHLPQHEHSFSQEKQTNPSRSTGD--- 1794
G S+ M+ M NT F + + Q + RS GD
Sbjct: 5160 NQSEGHESTRMARMASEKQSRKNTQSFKR---------------KPGQADNERSMGDHNE 5204
Query: 1795 ALDFRKEKINVSGDLPEDNIEHHGEMDDNNADEYGYVSEFEKGTTQALGPATLEQVDRNI 1854
+ R I S + E+ + +++ +A E+ S E Q A+ EQ +
Sbjct: 5205 RIHKRLRTIESSSEAKENTTQSKQNVEEADAFEHVKQSS-ECYDAQTYDVASKEQEKPIM 5263
Query: 1855 DVDKVDTESRAGEDANLQLEKQNSEIDSVSNSSLLPKN-----------EKRDQANMPVM 1903
++ + E ED ++ E QN ++ +V L P+ E+ + +
Sbjct: 5264 PLE--ENEEGEPEDTAMETEMQNEDLQAVDIEELKPETKSTASKTSGPGEEESKTQILDS 5321
Query: 1904 EKSQDDGSVKPLGSANIDPESHLEDLISISRSYLGENTHKLSQLSVND-EELGKYHE--- 1959
+ ++D K PE + I + +L + SQ V D EEL K E
Sbjct: 5322 DDAKDSAREKLPQVTEEKPERSKDSTIHTAHQFLMD----ASQHIVRDPEELRKELERQL 5377
Query: 1960 ------PCDAPDHVKDNATALWRRYELSTTKLSQELTEQLRLVLEPTVASKLQGYYKTGK 2013
+PD K+ A LW+RY + T LSQ+L EQLRL+LEPT A+KL+G Y+TGK
Sbjct: 5378 EAWQTQQSGSPDEEKE-AAQLWQRYLVLTAPLSQQLCEQLRLILEPTQAAKLKGDYRTGK 5436
Query: 2014 RIHMKKVIQFIASYYRMDKIWLRRTRPNKRDYQVVIAVDDSHSMSESCCGDVAVEALVTV 2073
R++M+KVI +IAS +R DKIWLRRT+P+KR YQ+ +A+DDS SM ++ +A E+L +
Sbjct: 5437 RLNMRKVIPYIASQFRKDKIWLRRTKPSKRQYQICLAIDDSSSMIDNHSKQLAYESLAVI 5496
Query: 2074 CRAVSQLEMGSLAVASFGTKGNINLLHDFDSPFTAESGVKVSRIYTSLVFFFIDISTVHL 2133
A++ LE+G +AV SFG + LLH F F+ +SG ++ R+
Sbjct: 5497 GNALTLLEVGQIAVCSFGE--TVQLLHPFHEQFSDQSGTRILRL---------------- 5538
Query: 2134 LNMLKGSDCSFLTEEQMVSNLTFKQENTIADEPVVDLLKFLTNKLDAAVVKARLPSGHNP 2193
F+Q+ T + +FL + +L NP
Sbjct: 5539 --------------------CKFQQKKT-------KIAQFLESSASMFAAAQQLSQNMNP 5571
Query: 2194 -LQQLVLIIADGR---FHEKDNLKRCVREALASNRMVAFLLLDN--SQESIMDLMEASFE 2247
QL+LI++DGR K+ + V+ A +N V F++LDN S++SI+D+ F
Sbjct: 5572 ETAQLLLIVSDGRGLFLEGKERVTAAVQAAQNANIFVIFVVLDNPNSRDSILDIKVPIFR 5631
Query: 2248 G-GKM-KFSKYMDSFPFPYYIVLRNIEALPRTLANLLRQ 2284
G G++ + YM+ FPFP+Y++LR++ ALP TL++ LRQ
Sbjct: 5632 GPGELPEIRSYMEEFPFPFYMILRDVNALPETLSDALRQ 5670
Score = 167 bits (422), Expect = 5e-39
Identities = 185/804 (23%), Positives = 322/804 (40%), Gaps = 96/804 (11%)
Query: 127 GCAWAHIGALRIHLLLSYNEVDPVMKYYCKYTQLEETISSLELEIQVRKECGYLSGQFLT 186
G W +IG L+I L DP +K K +E + LE E + LS Q T
Sbjct: 3347 GGLWVNIGLLQIQAWLPQTRFDPAVKREYKLKYAKEELHQLECEWRTND----LSSQLRT 3402
Query: 187 VEADKRKA-------------ERLEKLQAELRKLQRKIVFRSESWKYKKLMNECDEFLKH 233
++ + KA ER+++L ++ L RK FR + Y L E +++
Sbjct: 3403 GKSLEDKALSNYIHPHLRLLQERMQRLNEQISSLSRKKAFRPPAPLYDGLYQEAHQYINS 3462
Query: 234 IASLEVL----------VGNVEAEDLQQV---IDRTHSWQETAMCFINRLTDEYTAYNDI 280
IA + + +G + LQ + + SWQ++ F L +EY + D
Sbjct: 3463 IAKVSSVQDLLARLLKFLGGQRPKSLQAIKNLLSEEASWQQSHHHFRKHLAEEYAVFPDT 3522
Query: 281 IQPIQVAVYEMKFGLSLVLSSFLEKEYLRKVGHENINLVTDMIY---ILMRFPR--AASW 335
I P+Q A+ +++ G+ LV S + + NL+T ++ + FP A +
Sbjct: 3523 IVPLQAAILQLQHGMRLVASEVYAVLHGSVCPADLTNLLTSLLIFPSVGRSFPTYLARAE 3582
Query: 336 KFISVEDVGVDLHSSYKLDFGTDFYLNMGLIERLITLSSGVSADKKVSAMRCRASIYWNI 395
SV V V LH GL + + S G S + S + N
Sbjct: 3583 ILCSVNSVEV-LH---------------GLKKFSLKHSEGESEGVQKSCPTLE-QLLVNS 3625
Query: 396 LVQIAYSIANAKIIDRESYMLLHKIFDEFASLWMSMKVYAKSKSDHDAQQFKFKPRAFQI 455
L+ + + + +D++S L + + W + A+ + + ++F+ +
Sbjct: 3626 LLYLQCHVLSRGEMDQKSLQLFRHLCQAIINEWDEQERRAQEQEAMEKSLYRFRSKTHGK 3685
Query: 456 ESIMELEIPALANSSATEAFSDWKEFSYEEKSADNMESSEECE-ILDEEWKHLEESILDN 514
E E D+++ + + + ME+ E E L+ + L +S +
Sbjct: 3686 GQSEEEEEEEEFRRRFPFHEKDFEDITAQASLEEKMETGEPLEDQLEVDRALLSKSSMQT 3745
Query: 515 VVLIHSQLF--GSGDLVQAPGIFEISDEDRLHSFSESYKLGINLIKGAHSSNLASLDAKL 572
V+++H +L + L + + +F Y+ G L+ + A +++ L
Sbjct: 3746 VMMVHQRLCLNFAQSLWYQQSLPSHQAKHYFSAFISCYQTGACLVSQFYPLVGAEMNSSL 3805
Query: 573 IPEHLFYLSIDYRRKFHSSS-----KSANRYNFYKDSNAHEIEQMLKVLAPLRQQITSLL 627
+ L ++ + F + + Y+FY+ N ++ Q VL ++I LL
Sbjct: 3806 LGSQLLVSTLLHNTFFEEMTSDLVLQQDGPYDFYQHPNIKQVRQCQPVLENFAKEINRLL 3865
Query: 628 NEWEEQNDLQRFLDVIDMLLTLPSDIPLAKAFSGLQFLLHKAQVMQENHSK-FTFSNQLK 686
EW E L + L VID + + P PL+K +GL+ LL KAQ +EN S+ + L
Sbjct: 3866 QEWPEHPVLLQLLVVIDRIQSFPLSSPLSKFLNGLEILLAKAQDWEENASRALSLRKHLD 3925
Query: 687 SVFDLMSSWHKMELGSWPVLLDEVMDQYENNAKKSVLS--SSIHYF*SINFPKSNFYFSY 744
V L+ W ++EL W V LD + Q+ + K S I +
Sbjct: 3926 LVTQLIIQWRRLELNCWSVSLDNITKQHVEKSTKHWFSLYQMIEKYVQEQTKADKEETEL 3985
Query: 745 ESC-----SLEDFIQTSSFGEFRKRLQLLYAFLGQNHTSACLKINSSNIVFFLHCWTLQL 799
S +L+ FI+ S+ GEF RLQ L F HC L +
Sbjct: 3986 MSLKMLVNTLQAFIEGSTLGEFHARLQALLVF---------------------HCHVLLM 4024
Query: 800 LSDGAVNILVQYVWIL-------CAVLTNHIDASRKEILTELKDLVKLCRWEQDKSYSSI 852
+IL +W L + I R+ I ELK+ VK+ +W ++
Sbjct: 4025 PQLAEKDILCSILWNLYNYYKQFSECVETRITELRQPIEKELKEFVKISKWNDVSFWAIK 4084
Query: 853 ENLKKSRQKLKKLIKKHTDILQEP 876
++++K+R+ L K +KK +L EP
Sbjct: 4085 QSVEKTRRTLFKFMKKFEVVLNEP 4108
Score = 66.2 bits (160), Expect = 1e-08
Identities = 113/562 (20%), Positives = 209/562 (37%), Gaps = 57/562 (10%)
Query: 1442 CLLSMMQKKEEQEESKEVPGNDNTGIEMDQDFQADAVSLSEDSSENEDCDGENEELESEM 1501
CL + + E E + + + GI D + + D E + ED + EE E E
Sbjct: 4757 CLPKELLEDEAGEGATQFHDYEEGGIG-DGEGKKDVSDKIESEDQIEDSFKKGEEKEKED 4815
Query: 1502 GPTGPDSEAVGEKIWDQNEDETPDDTGEKYESGPSVKDGDGSNKELRAKDDSTSDQSGDD 1561
+ PD E + N E +D K G K +++ T +
Sbjct: 4816 QDSKPDIEG------EDNAIEMSEDFEGKMHDGEQEKK---VIQKVAVLALQTLYLLCTE 4866
Query: 1562 SCDEGDAQNDEAAAQNEFDDEENGDDVNMDKEAAHSDATGLKPDEPDHSSDMEIDLNANE 1621
+ E +NDE + + E D++ GD N + + + L DE D D + A E
Sbjct: 4867 TYPELYTENDEKSDEEEELDKQMGDLDNAEADDKLDER--LWGDEEDDDDDEDASSKAEE 4924
Query: 1622 DVDPIEEGDQE--GHDDSAENGNQEDETCPPDEIMEEAHTEVDVSSEKDDLGQEHQEND- 1678
++E D E DD+ GN++++ PP + EE + + + K+ + ++ E +
Sbjct: 4925 TGPGMDEEDSELVAKDDNLGTGNKDNKKQPPKD--EETENQTEDNENKEKIHEQIDEREY 4982
Query: 1679 DMNSMDPKNDTSESSDVVNP--QVSNVDLASQSKSDLQTSGSENIASQSNLSNSHHDFGN 1736
D N +DP + E V P N++L KSD + G E + + D
Sbjct: 4983 DENEVDPYHGQQEKQPEVEPLDLPDNLNLEDDEKSDGEKEGEEEEENAFEIDEKPVDLNE 5042
Query: 1737 PAVTGGFPSSDMSEMDINMSDSSNTGGFSKTQPKSHLPQHEHSFSQEKQTNPSRSTGDAL 1796
T G + SE + GG +P + + + ++ P +
Sbjct: 5043 AENTEGQNEENNSEAE---------GGDKDAEPAEEEEEEKGIPAADQGLQPQNVQIKPI 5093
Query: 1797 DFRKEKINVSGDLPEDNIEHHGEMDDNNADEYGYVSEFEKGTTQALGPATLEQVDRNIDV 1856
F++E+ + ++ E E M+ + G + + G A+
Sbjct: 5094 SFQQEEDKDNPEMDEQVPESEERMEHETQGQTGQENLQSDSAVELAGEAS---------- 5143
Query: 1857 DKVDTESRAGEDANLQLEKQNSEIDSVSNSSLLPKNEKRDQANMPVMEKSQDDGSVKPLG 1916
++ ++ G A + + E ++ + ++ K Q+ K + + +G
Sbjct: 5144 ERDQSKEEYGSGAASANQSEGHESTRMARMASEKQSRKNTQS---FKRKPGQADNERSMG 5200
Query: 1917 SANIDPESHLEDLISISRSYLGENTHKLSQLSVNDEELGKYHEPCDAPDHVKDNATALWR 1976
N L + S S + ENT +Q N EE DA +HVK ++
Sbjct: 5201 DHNERIHKRLRTIESSSEA--KENT---TQSKQNVEE-------ADAFEHVKQSSEC--- 5245
Query: 1977 RYELSTTKLSQELTEQLRLVLE 1998
Y+ T ++ + E+ + LE
Sbjct: 5246 -YDAQTYDVASKEQEKPIMPLE 5266
>emb|CAI16236.1| MDN1, midasin homolog (yeast) [Homo sapiens]
gi|55958031|emb|CAI13203.1| MDN1, midasin homolog (yeast)
[Homo sapiens] gi|57208480|emb|CAI42279.1| MDN1, midasin
homolog (yeast) [Homo sapiens] gi|21842179|gb|AAM77722.1|
midasin [Homo sapiens] gi|24415404|ref|NP_055426.1| MDN1,
midasin homolog [Homo sapiens]
gi|24212017|sp|Q9NU22|MDN1_HUMAN Midasin
(MIDAS-containing protein)
Length = 5596
Score = 271 bits (693), Expect = 2e-70
Identities = 251/931 (26%), Positives = 413/931 (43%), Gaps = 152/931 (16%)
Query: 1450 KEEQEESKEVPGNDNTGIEMDQDFQADAVS--LSEDSSENEDCDGENEELESEMGP-TGP 1506
KE+ + ++ G DN IEM +DF L E ++E D E +L+ MG G
Sbjct: 4711 KEDPDSKSDIKGEDNA-IEMSEDFDGKMHDGELEEQEEDDEKSDSEGGDLDKHMGDLNGE 4769
Query: 1507 DSEAVGEKIW---DQNEDETPDDTGEKYESGPSVKDGDGSNKELRAKDDSTSDQSGDDSC 1563
+++ + E++W D+ EDE +D + E+GP + + D EL AKDD+ SG+ +
Sbjct: 4770 EADKLDERLWGDDDEEEDEEEEDNKTE-ETGPGMDEEDS---ELVAKDDNLD--SGNSNK 4823
Query: 1564 DEGDAQNDEAAAQNEFDDEENGDD-VNMDKEAAHSDATGLKP--------------DEPD 1608
D+ E + E DD G+D +N + D + P D PD
Sbjct: 4824 DKSQQDKKEEKEEAEADDGGQGEDKINEQIDERDYDENEVDPYHGNQEKVPEPEALDLPD 4883
Query: 1609 HSSDMEIDLNANEDVDPIEEGDQE------------GH----------DDSAENGNQEDE 1646
+ D N ED D EEG++E GH D + QE E
Sbjct: 4884 DLNLDSEDKNGGEDTDN-EEGEEENPLEIKEKPEEAGHEAEERGETETDQNESQSPQEPE 4942
Query: 1647 TCPPDEIMEEAHTEVDVSSEKDDLG-----QEHQENDDMNSMDPKNDTSESSDVVNPQVS 1701
P ++ E E+D ++ D +EH E + + + E P +
Sbjct: 4943 EGPSEDDKAEGEEEMDTGADDQDGDAAQHPEEHSEEQQQSVEEKDKEADEEGGENGP--A 5000
Query: 1702 NVDLASQSKSDLQTSGSENIASQSNLSNSHHDFGNPAV-----------TGGFPSSDMSE 1750
+ Q + + + S +E ++ H G V G P + +
Sbjct: 5001 DQGFQPQEEEEREDSDTEEQVPEALERKEHASCGQTGVENMQNTQAMELAGAAPEKEQGK 5060
Query: 1751 -------MDINMSDSSNTGGFSKTQPKSHLPQHEHSFSQEK-QTNPSRSTGDALDFRKEK 1802
D N ++ + ++ + H ++ SF ++ Q + RS GD + ++
Sbjct: 5061 EEHGSGAADANQAEGHESNFIAQLASQKHTRKNTQSFKRKPGQADNERSMGDHNERVHKR 5120
Query: 1803 INV--SGDLPEDNIEHHGEMDDNNADEYGYVSEFEKG-TTQALGPATLEQVDRNIDVDKV 1859
+ + E + +AD + ++ + Q A+ EQ D K
Sbjct: 5121 LRTVDTDSHAEQGPAQQPQAQVEDADAFEHIKQGSDAYDAQTYDVASKEQQQSAKDSGK- 5179
Query: 1860 DTESRAGEDANLQLEKQNSEIDSVSNSSLLPKNEKR--------DQANMPVM----EKSQ 1907
D E ED + E+Q E + L P+ K D+ + + E+ Q
Sbjct: 5180 DQEEEEIEDTLMDTEEQE-EFKAADVEQLKPEEIKSGTTAPLGFDEMEVEIQTVKTEEDQ 5238
Query: 1908 DDGSVKP-LGSANIDPESHLEDLISISRSYLGENTHKLSQLSVND--EELGKYHE---PC 1961
D + K + N PE E I + +L + + VN+ +EL + E P
Sbjct: 5239 DPRTDKAHKETENEKPERSRESTIHTAHQFLMDTIFQPFLKDVNELRQELERQLEMWQPR 5298
Query: 1962 DAPDHVKDNATA-LWRRYELSTTKLSQELTEQLRLVLEPTVASKLQGYYKTGKRIHMKKV 2020
++ + ++ A +W+ Y + T LSQ L E+LRL+LEPT A+KL+G Y+TGKR++++KV
Sbjct: 5299 ESGNPEEEKVAAEMWQSYLILTAPLSQRLCEELRLILEPTQAAKLKGDYRTGKRLNIRKV 5358
Query: 2021 IQFIASYYRMDKIWLRRTRPNKRDYQVVIAVDDSHSMSESCCGDVAVEALVTVCRAVSQL 2080
I +IAS +R DKIWLRRT+P+KR YQ+ +A+DDS SM ++ +A E+L + A++ L
Sbjct: 5359 IPYIASQFRKDKIWLRRTKPSKRQYQICLAIDDSSSMVDNHTKQLAFESLAVIGNALTLL 5418
Query: 2081 EMGSLAVASFGTKGNINLLHDFDSPFTAESGVKVSRIYTSLVFFFIDISTVHLLNMLKGS 2140
E+G +AV SFG ++ LLH F F+ SG ++ R+
Sbjct: 5419 EVGQIAVCSFGE--SVKLLHPFHEQFSDYSGSQILRL----------------------- 5453
Query: 2141 DCSFLTEEQMVSNLTFKQENTIADEPVVDLLKFLTNKLDAAVVKARLPSGHNPLQQLVLI 2200
F+Q+ T + L+ + N AA ++ S QL+L+
Sbjct: 5454 -------------CKFQQKKT----KIAQFLESVANMFAAAQQLSQNISSETA--QLLLV 5494
Query: 2201 IADGR---FHEKDNLKRCVREALASNRMVAFLLLDN--SQESIMDLMEASFEG-GKM-KF 2253
++DGR K+ + V+ A +N V F++LDN S++SI+D+ F+G G+M +
Sbjct: 5495 VSDGRGLFLEGKERVLAAVQAARNANIFVIFVVLDNPSSRDSILDIKVPIFKGPGEMPEI 5554
Query: 2254 SKYMDSFPFPYYIVLRNIEALPRTLANLLRQ 2284
YM+ FPFPYYI+LR++ ALP TL++ LRQ
Sbjct: 5555 RSYMEEFPFPYYIILRDVNALPETLSDALRQ 5585
Score = 170 bits (431), Expect = 5e-40
Identities = 187/853 (21%), Positives = 335/853 (38%), Gaps = 120/853 (14%)
Query: 127 GCAWAHIGALRIHLLLSYNEVDPVMKYYCKYTQLEETISSLELEIQVRKECGYLSGQFLT 186
G W +G L+I L DP +K K ++E + L+ E + R LS Q T
Sbjct: 3221 GSLWVSLGLLQIQTWLPQARFDPAVKREYKLNYVKEELHQLQCEWKTRN----LSSQLQT 3276
Query: 187 ----------------VEADKRKAERLEKLQAELRKLQRKIVFRSESWKYKKLMNECDEF 230
V +++ +RL+ L L K Q FR + Y+ L+ E +
Sbjct: 3277 GRDLEDEVVVSYSHPHVRLLRQRMDRLDNLTCHLLKKQ---AFRPQLPAYESLVQEIHHY 3333
Query: 231 LKHIASLEVLV-------------GNVEAEDLQQVIDRTHSWQETAMCFINRLTDEYTAY 277
+ IA + G A+ Q ++ SWQ++ F RL++EYT Y
Sbjct: 3334 VTSIAKAPAVQDLLTRLLQALHIDGPRSAQVAQSLLKEEASWQQSHHQFRKRLSEEYTFY 3393
Query: 278 NDIIQPIQVAVYEMKFGLSLVLSSFLEKEYLRKVGHENINLVTDMIYILMRFPRAASW-- 335
D + P+Q ++ +++ G+ LV S + VG + + + L+ FP
Sbjct: 3394 PDAVSPLQASILQLQHGMRLVASELHTSLHSSMVGADRLGTLATA---LLAFPSVGPTFP 3450
Query: 336 KFISVEDVGVDLHSSYKLDFGTDFYLNMGLIERLITLSSGVSADKK-VSAMRCRASIYWN 394
+ + D + S L GL + ++ S G + K A R + N
Sbjct: 3451 TYYAHADTLCSVKSEEVL---------RGLGKLILKRSGGKELEGKGQKACPTREQLLMN 3501
Query: 395 ILVQIAYSIANAKIIDRESYMLLHKIFDEFASLWMSMKVYAKSKSDHDAQQFKFKPRAFQ 454
L+ + + +D+ + L + E S W + A+ K++ ++ ++++ R +
Sbjct: 3502 ALLYLRSHVLCKGELDQRALQLFRHVCQEIISEWDEQERIAQEKAEQESGLYRYRSRNSR 3561
Query: 455 IESIMELEIPALANSSATEAFSDWKEFSYEEKSADNMESSEECEILDEEWKH---LEESI 511
E E D+ + + +N +S+ E +E + L ++
Sbjct: 3562 TALSEEEEEEREFRKQFPLHEKDFADILVQPTLEENKGTSDGQE--EEAGTNPALLSQNS 3619
Query: 512 LDNVVLIHSQLF--GSGDLVQAPGIFEISDEDRLHSFSESYKLGINLIKGAHSSNLASLD 569
+ V+LIH QL + L + + L F Y+ G +L+ + L+
Sbjct: 3620 MQAVMLIHQQLCLNFARSLWYQQTLPPHEAKHYLSLFLSCYQTGASLVTHFYPLMGVELN 3679
Query: 570 AKLIPEHLFYLSIDYRRKFHSSS-----KSANRYNFYKDSNAHEIEQMLKVLAPLRQQIT 624
+L+ L ++ + F + K Y+FY+ N E Q VL + ++
Sbjct: 3680 DRLLGSQLLACTLSHNTLFGEAPSDLMVKPDGPYDFYQHPNVPEARQCQPVLQGFSEAVS 3739
Query: 625 SLLNEWEEQNDLQRFLDVIDMLLTLPSDIPLAKAFSGLQFLLHKAQVMQENHSK-FTFSN 683
LL +W E L++ L V+D + + P P++K +GL+ LL KAQ +EN S+ +
Sbjct: 3740 HLLQDWPEHPALEQLLVVMDRIRSFPLSSPISKFLNGLEILLAKAQDWEENASRALSLRK 3799
Query: 684 QLKSVFDLMSSWHKMELGSWPVLLDEVMDQYENNAKKSVLSSSIHYF*SINFPKSNFYFS 743
L + ++ W K+EL W + LD M ++ + K H+F + +
Sbjct: 3800 HLDLISQMIIRWRKLELNCWSMSLDNTMKRHTEKSTK-------HWFSIYQMLEKHMQEQ 3852
Query: 744 YES-------------CSLEDFIQTSSFGEFRKRLQLLYAFLGQNHTSACLKINSSNIVF 790
E +L+ FI+ SS GEF RLQ+L F
Sbjct: 3853 TEEQEDDKQMTLMLLVSTLQAFIEGSSLGEFHVRLQMLLVF------------------- 3893
Query: 791 FLHCWTLQLLSDGAVNILVQYVWILCAVLTNHIDASRKEIL-------TELKDLVKLCRW 843
HC L + + L +W L D + +I+ ELK+ VK+ +W
Sbjct: 3894 --HCHVLLMPQVEGKDSLCSVLWNLYHYYKQFFDRVQAKIVELRSPLEKELKEFVKISKW 3951
Query: 844 EQDKSYSSIENLKKSRQKLKKLIKKHTDILQEPMDKLI--------RDVLHKGSISGVSD 895
+S ++++K+ + L K +KK +L EP + D L + + S+
Sbjct: 3952 NDVSFWSIKQSVEKTHRTLFKFMKKFEAVLSEPCRSSLVESDKEEQPDFLPRPTDGAASE 4011
Query: 896 LPLFSDENRLYQE 908
L + NR +E
Sbjct: 4012 LSSIQNLNRALRE 4024
Score = 56.2 bits (134), Expect = 1e-05
Identities = 74/335 (22%), Positives = 130/335 (38%), Gaps = 47/335 (14%)
Query: 1520 EDETPDDTGEKYESGPSVKDGDGSNKELRAKD-DSTSDQSGDDSCDE---------GDAQ 1569
E E D ++ + V+D +E +D DS SD G+D+ E D +
Sbjct: 4682 EGEGMKDVSDQIGNEEQVEDTFQKGQEKDKEDPDSKSDIKGEDNAIEMSEDFDGKMHDGE 4741
Query: 1570 NDEAAAQNEFDDEENGDDVNMDKEAAHSDATGLKPD--------EPDHSSDMEIDLNANE 1621
+E +E D E GD +DK D G + D + D D E + N E
Sbjct: 4742 LEEQEEDDEKSDSEGGD---LDKHM--GDLNGEEADKLDERLWGDDDEEEDEEEEDNKTE 4796
Query: 1622 DVDP-IEEGDQE--GHDDSAENGNQEDETCPPDEIMEEAHTEVDVSSE-KDDLGQEHQEN 1677
+ P ++E D E DD+ ++GN + D+ E+ E D + +D + ++ E
Sbjct: 4797 ETGPGMDEEDSELVAKDDNLDSGNSNKDKSQQDKKEEKEEAEADDGGQGEDKINEQIDER 4856
Query: 1678 D-DMNSMDPKNDTSESSDVVNPQVSNVDLASQSKSDLQ-TSGSENIASQSNLSNSHHDFG 1735
D D N +DP + E P+ +DL D + +G E+ ++ + +
Sbjct: 4857 DYDENEVDPYHGNQEKV----PEPEALDLPDDLNLDSEDKNGGEDTDNEEGEEENPLEIK 4912
Query: 1736 NPAVTGGFPSSDMSEMDINMSDSSNTGGFSKTQPKSHLPQHEHSFSQEK-QTNPSRSTGD 1794
G + + E + + ++S S +P+ + + + +E+ T GD
Sbjct: 4913 EKPEEAGHEAEERGETETDQNESQ-----SPQEPEEGPSEDDKAEGEEEMDTGADDQDGD 4967
Query: 1795 ALDFRKEKINVSGDLPEDNIEHHGEMDDNNADEYG 1829
A +E + + E D ADE G
Sbjct: 4968 AAQHPEEH--------SEEQQQSVEEKDKEADEEG 4994
>dbj|BAA20761.2| KIAA0301 [Homo sapiens]
Length = 3210
Score = 271 bits (693), Expect = 2e-70
Identities = 251/931 (26%), Positives = 413/931 (43%), Gaps = 152/931 (16%)
Query: 1450 KEEQEESKEVPGNDNTGIEMDQDFQADAVS--LSEDSSENEDCDGENEELESEMGP-TGP 1506
KE+ + ++ G DN IEM +DF L E ++E D E +L+ MG G
Sbjct: 2325 KEDPDSKSDIKGEDNA-IEMSEDFDGKMHDGELEEQEEDDEKSDSEGGDLDKHMGDLNGE 2383
Query: 1507 DSEAVGEKIW---DQNEDETPDDTGEKYESGPSVKDGDGSNKELRAKDDSTSDQSGDDSC 1563
+++ + E++W D+ EDE +D + E+GP + + D EL AKDD+ SG+ +
Sbjct: 2384 EADKLDERLWGDDDEEEDEEEEDNKTE-ETGPGMDEEDS---ELVAKDDNLD--SGNSNK 2437
Query: 1564 DEGDAQNDEAAAQNEFDDEENGDD-VNMDKEAAHSDATGLKP--------------DEPD 1608
D+ E + E DD G+D +N + D + P D PD
Sbjct: 2438 DKSQQDKKEEKEEAEADDGGQGEDKINEQIDERDYDENEVDPYHGNQEKVPEPEALDLPD 2497
Query: 1609 HSSDMEIDLNANEDVDPIEEGDQE------------GH----------DDSAENGNQEDE 1646
+ D N ED D EEG++E GH D + QE E
Sbjct: 2498 DLNLDSEDKNGGEDTDN-EEGEEENPLEIKEKPEEAGHEAEERGETETDQNESQSPQEPE 2556
Query: 1647 TCPPDEIMEEAHTEVDVSSEKDDLG-----QEHQENDDMNSMDPKNDTSESSDVVNPQVS 1701
P ++ E E+D ++ D +EH E + + + E P +
Sbjct: 2557 EGPSEDDKAEGEEEMDTGADDQDGDAAQHPEEHSEEQQQSVEEKDKEADEEGGENGP--A 2614
Query: 1702 NVDLASQSKSDLQTSGSENIASQSNLSNSHHDFGNPAV-----------TGGFPSSDMSE 1750
+ Q + + + S +E ++ H G V G P + +
Sbjct: 2615 DQGFQPQEEEEREDSDTEEQVPEALERKEHASCGQTGVENMQNTQAMELAGAAPEKEQGK 2674
Query: 1751 -------MDINMSDSSNTGGFSKTQPKSHLPQHEHSFSQEK-QTNPSRSTGDALDFRKEK 1802
D N ++ + ++ + H ++ SF ++ Q + RS GD + ++
Sbjct: 2675 EEHGSGAADANQAEGHESNFIAQLASQKHTRKNTQSFKRKPGQADNERSMGDHNERVHKR 2734
Query: 1803 INV--SGDLPEDNIEHHGEMDDNNADEYGYVSEFEKG-TTQALGPATLEQVDRNIDVDKV 1859
+ + E + +AD + ++ + Q A+ EQ D K
Sbjct: 2735 LRTVDTDSHAEQGPAQQPQAQVEDADAFEHIKQGSDAYDAQTYDVASKEQQQSAKDSGK- 2793
Query: 1860 DTESRAGEDANLQLEKQNSEIDSVSNSSLLPKNEKR--------DQANMPVM----EKSQ 1907
D E ED + E+Q E + L P+ K D+ + + E+ Q
Sbjct: 2794 DQEEEEIEDTLMDTEEQE-EFKAADVEQLKPEEIKSGTTAPLGFDEMEVEIQTVKTEEDQ 2852
Query: 1908 DDGSVKP-LGSANIDPESHLEDLISISRSYLGENTHKLSQLSVND--EELGKYHE---PC 1961
D + K + N PE E I + +L + + VN+ +EL + E P
Sbjct: 2853 DPRTDKAHKETENEKPERSRESTIHTAHQFLMDTIFQPFLKDVNELRQELERQLEMWQPR 2912
Query: 1962 DAPDHVKDNATA-LWRRYELSTTKLSQELTEQLRLVLEPTVASKLQGYYKTGKRIHMKKV 2020
++ + ++ A +W+ Y + T LSQ L E+LRL+LEPT A+KL+G Y+TGKR++++KV
Sbjct: 2913 ESGNPEEEKVAAEMWQSYLILTAPLSQRLCEELRLILEPTQAAKLKGDYRTGKRLNIRKV 2972
Query: 2021 IQFIASYYRMDKIWLRRTRPNKRDYQVVIAVDDSHSMSESCCGDVAVEALVTVCRAVSQL 2080
I +IAS +R DKIWLRRT+P+KR YQ+ +A+DDS SM ++ +A E+L + A++ L
Sbjct: 2973 IPYIASQFRKDKIWLRRTKPSKRQYQICLAIDDSSSMVDNHTKQLAFESLAVIGNALTLL 3032
Query: 2081 EMGSLAVASFGTKGNINLLHDFDSPFTAESGVKVSRIYTSLVFFFIDISTVHLLNMLKGS 2140
E+G +AV SFG ++ LLH F F+ SG ++ R+
Sbjct: 3033 EVGQIAVCSFGE--SVKLLHPFHEQFSDYSGSQILRL----------------------- 3067
Query: 2141 DCSFLTEEQMVSNLTFKQENTIADEPVVDLLKFLTNKLDAAVVKARLPSGHNPLQQLVLI 2200
F+Q+ T + L+ + N AA ++ S QL+L+
Sbjct: 3068 -------------CKFQQKKT----KIAQFLESVANMFAAAQQLSQNISSETA--QLLLV 3108
Query: 2201 IADGR---FHEKDNLKRCVREALASNRMVAFLLLDN--SQESIMDLMEASFEG-GKM-KF 2253
++DGR K+ + V+ A +N V F++LDN S++SI+D+ F+G G+M +
Sbjct: 3109 VSDGRGLFLEGKERVLAAVQAARNANIFVIFVVLDNPSSRDSILDIKVPIFKGPGEMPEI 3168
Query: 2254 SKYMDSFPFPYYIVLRNIEALPRTLANLLRQ 2284
YM+ FPFPYYI+LR++ ALP TL++ LRQ
Sbjct: 3169 RSYMEEFPFPYYIILRDVNALPETLSDALRQ 3199
Score = 172 bits (436), Expect = 1e-40
Identities = 188/853 (22%), Positives = 335/853 (39%), Gaps = 120/853 (14%)
Query: 127 GCAWAHIGALRIHLLLSYNEVDPVMKYYCKYTQLEETISSLELEIQVRKECGYLSGQFLT 186
G W +G L+I L DP +K K ++E + L+ E + R LS Q T
Sbjct: 835 GSLWVSLGLLQIQTWLPQARFDPAVKREYKLNYVKEELHQLQCEWKTRN----LSSQLQT 890
Query: 187 ----------------VEADKRKAERLEKLQAELRKLQRKIVFRSESWKYKKLMNECDEF 230
V +++ +RL+ L L K Q FR + Y+ L+ E +
Sbjct: 891 GRDLEDEVVVSYSHPHVRLLRQRMDRLDNLTCHLLKKQ---AFRPQLPAYESLVQEIHHY 947
Query: 231 LKHIASLEVLV-------------GNVEAEDLQQVIDRTHSWQETAMCFINRLTDEYTAY 277
+ IA + G A+ Q ++ SWQ++ F RL++EYT Y
Sbjct: 948 VTSIAKAPAVQDLLTRLLQALHIDGPRSAQVAQSLLKEEASWQQSHHQFRKRLSEEYTFY 1007
Query: 278 NDIIQPIQVAVYEMKFGLSLVLSSFLEKEYLRKVGHENINLVTDMIYILMRFPRAASW-- 335
D + P+Q ++ +++ G+ LV S Y VG + + + L+ FP
Sbjct: 1008 PDAVSPLQASILQLQHGMRLVASELHTSLYSSMVGADRLGTLATA---LLAFPSVGPTFP 1064
Query: 336 KFISVEDVGVDLHSSYKLDFGTDFYLNMGLIERLITLSSGVSADKK-VSAMRCRASIYWN 394
+ + D + S L GL + ++ S G + K A R + N
Sbjct: 1065 TYYAHADTLCSVKSEEVL---------RGLGKLILKRSGGKELEGKGQKACPTREQLLMN 1115
Query: 395 ILVQIAYSIANAKIIDRESYMLLHKIFDEFASLWMSMKVYAKSKSDHDAQQFKFKPRAFQ 454
L+ + + +D+ + L + E S W + A+ K++ ++ ++++ R +
Sbjct: 1116 ALLYLRSHVLCKGELDQRALQLFRHVCQEIISEWDEQERIAQEKAEQESGLYRYRSRNSR 1175
Query: 455 IESIMELEIPALANSSATEAFSDWKEFSYEEKSADNMESSEECEILDEEWKH---LEESI 511
E E D+ + + +N +S+ E +E + L ++
Sbjct: 1176 TALSEEEEEEREFRKQFPLHEKDFADILVQPTLEENKGTSDGQE--EEAGTNPALLSQNS 1233
Query: 512 LDNVVLIHSQLF--GSGDLVQAPGIFEISDEDRLHSFSESYKLGINLIKGAHSSNLASLD 569
+ V+LIH QL + L + + L F Y+ G +L+ + L+
Sbjct: 1234 MQAVMLIHQQLCLNFARSLWYQQTLPPHEAKHYLSLFLSCYQTGASLVTHFYPLMGVELN 1293
Query: 570 AKLIPEHLFYLSIDYRRKFHSSS-----KSANRYNFYKDSNAHEIEQMLKVLAPLRQQIT 624
+L+ L ++ + F + K Y+FY+ N E Q VL + ++
Sbjct: 1294 DRLLGSQLLACTLSHNTLFGEAPSDLMVKPDGPYDFYQHPNVPEARQCQPVLQGFSEAVS 1353
Query: 625 SLLNEWEEQNDLQRFLDVIDMLLTLPSDIPLAKAFSGLQFLLHKAQVMQENHSK-FTFSN 683
LL +W E L++ L V+D + + P P++K +GL+ LL KAQ +EN S+ +
Sbjct: 1354 HLLQDWPEHPALEQLLVVMDRIRSFPLSSPISKFLNGLEILLAKAQDWEENASRALSLRK 1413
Query: 684 QLKSVFDLMSSWHKMELGSWPVLLDEVMDQYENNAKKSVLSSSIHYF*SINFPKSNFYFS 743
L + ++ W K+EL W + LD M ++ + K H+F + +
Sbjct: 1414 HLDLISQMIIRWRKLELNCWSMSLDNTMKRHTEKSTK-------HWFSIYQMLEKHMQEQ 1466
Query: 744 YES-------------CSLEDFIQTSSFGEFRKRLQLLYAFLGQNHTSACLKINSSNIVF 790
E +L+ FI+ SS GEF RLQ+L F
Sbjct: 1467 TEEQEDDKQMTLMLLVSTLQAFIEGSSLGEFHVRLQMLLVF------------------- 1507
Query: 791 FLHCWTLQLLSDGAVNILVQYVWILCAVLTNHIDASRKEIL-------TELKDLVKLCRW 843
HC L + + L +W L D + +I+ ELK+ VK+ +W
Sbjct: 1508 --HCHVLLMPQVEGKDSLCSVLWNLYHYYKQFFDRVQAKIVELRSPLEKELKEFVKISKW 1565
Query: 844 EQDKSYSSIENLKKSRQKLKKLIKKHTDILQEPMDKLI--------RDVLHKGSISGVSD 895
+S ++++K+ + L K +KK +L EP + D L + + S+
Sbjct: 1566 NDVSFWSIKQSVEKTHRTLFKFMKKFEAVLSEPCRSSLVESDKEEQPDFLPRPTDGAASE 1625
Query: 896 LPLFSDENRLYQE 908
L + NR +E
Sbjct: 1626 LSSIQNLNRALRE 1638
Score = 56.2 bits (134), Expect = 1e-05
Identities = 74/335 (22%), Positives = 130/335 (38%), Gaps = 47/335 (14%)
Query: 1520 EDETPDDTGEKYESGPSVKDGDGSNKELRAKD-DSTSDQSGDDSCDE---------GDAQ 1569
E E D ++ + V+D +E +D DS SD G+D+ E D +
Sbjct: 2296 EGEGMKDVSDQIGNEEQVEDTFQKGQEKDKEDPDSKSDIKGEDNAIEMSEDFDGKMHDGE 2355
Query: 1570 NDEAAAQNEFDDEENGDDVNMDKEAAHSDATGLKPD--------EPDHSSDMEIDLNANE 1621
+E +E D E GD +DK D G + D + D D E + N E
Sbjct: 2356 LEEQEEDDEKSDSEGGD---LDKHM--GDLNGEEADKLDERLWGDDDEEEDEEEEDNKTE 2410
Query: 1622 DVDP-IEEGDQE--GHDDSAENGNQEDETCPPDEIMEEAHTEVDVSSE-KDDLGQEHQEN 1677
+ P ++E D E DD+ ++GN + D+ E+ E D + +D + ++ E
Sbjct: 2411 ETGPGMDEEDSELVAKDDNLDSGNSNKDKSQQDKKEEKEEAEADDGGQGEDKINEQIDER 2470
Query: 1678 D-DMNSMDPKNDTSESSDVVNPQVSNVDLASQSKSDLQ-TSGSENIASQSNLSNSHHDFG 1735
D D N +DP + E P+ +DL D + +G E+ ++ + +
Sbjct: 2471 DYDENEVDPYHGNQEKV----PEPEALDLPDDLNLDSEDKNGGEDTDNEEGEEENPLEIK 2526
Query: 1736 NPAVTGGFPSSDMSEMDINMSDSSNTGGFSKTQPKSHLPQHEHSFSQEK-QTNPSRSTGD 1794
G + + E + + ++S S +P+ + + + +E+ T GD
Sbjct: 2527 EKPEEAGHEAEERGETETDQNESQ-----SPQEPEEGPSEDDKAEGEEEMDTGADDQDGD 2581
Query: 1795 ALDFRKEKINVSGDLPEDNIEHHGEMDDNNADEYG 1829
A +E + + E D ADE G
Sbjct: 2582 AAQHPEEH--------SEEQQQSVEEKDKEADEEG 2608
>emb|CAH10492.1| hypothetical protein [Homo sapiens]
Length = 2810
Score = 268 bits (686), Expect = 1e-69
Identities = 250/931 (26%), Positives = 412/931 (43%), Gaps = 152/931 (16%)
Query: 1450 KEEQEESKEVPGNDNTGIEMDQDFQADAVS--LSEDSSENEDCDGENEELESEMGP-TGP 1506
KE+ + ++ G DN IEM +DF L E ++E D E +L+ MG G
Sbjct: 1925 KEDPDSKSDIKGEDNA-IEMSEDFDGKMHDGELEEQEEDDEKSDSEGGDLDKHMGDLNGE 1983
Query: 1507 DSEAVGEKIW---DQNEDETPDDTGEKYESGPSVKDGDGSNKELRAKDDSTSDQSGDDSC 1563
+++ + E++W D+ EDE +D + E+GP + + D EL AKDD+ SG+ +
Sbjct: 1984 EADKLDERLWGDDDEEEDEEEEDNKTE-ETGPGMDEEDS---ELVAKDDNLD--SGNSNK 2037
Query: 1564 DEGDAQNDEAAAQNEFDDEENGDD-VNMDKEAAHSDATGLKP--------------DEPD 1608
D+ E + E DD G+D +N + D + P D PD
Sbjct: 2038 DKSQQDKKEEKEEAEADDGGQGEDKINEQIDERDYDENEVDPYHGNQEKVPEPEALDLPD 2097
Query: 1609 HSSDMEIDLNANEDVDPIEEGDQE------------GH----------DDSAENGNQEDE 1646
+ D N ED D EEG++E GH D + QE E
Sbjct: 2098 DLNLDSEDKNGGEDTDN-EEGEEENPLEIKEKPEEAGHEAEERGETETDQNESQSPQEPE 2156
Query: 1647 TCPPDEIMEEAHTEVDVSSEKDDLG-----QEHQENDDMNSMDPKNDTSESSDVVNPQVS 1701
P ++ E E+D ++ D +EH E + + + E P +
Sbjct: 2157 EGPSEDDKAEGEEEMDTGADDQDGDAAQHPEEHSEEQQQSVEEKDKEADEEGGENGP--A 2214
Query: 1702 NVDLASQSKSDLQTSGSENIASQSNLSNSHHDFGNPAV-----------TGGFPSSDMSE 1750
+ Q + + + S +E ++ H G V G P + +
Sbjct: 2215 DQGFQPQEEEEREDSDTEEQVPEALERKEHASCGQTGVENMQNTQAMELAGAAPEKEQGK 2274
Query: 1751 -------MDINMSDSSNTGGFSKTQPKSHLPQHEHSFSQEK-QTNPSRSTGDALDFRKEK 1802
D N ++ + ++ + H ++ SF ++ Q + RS GD + ++
Sbjct: 2275 EEHGSGAADANQAEGHESNFIAQLASQKHTRKNTQSFKRKPGQADNERSMGDHNERVHKR 2334
Query: 1803 INV--SGDLPEDNIEHHGEMDDNNADEYGYVSEFEKG-TTQALGPATLEQVDRNIDVDKV 1859
+ + E + +AD + ++ + Q A+ EQ D K
Sbjct: 2335 LRTVDTDSHAEQGPAQQPQAQVEDADAFEHIKQGSDAYDAQTYDVASKEQQQSAKDSGK- 2393
Query: 1860 DTESRAGEDANLQLEKQNSEIDSVSNSSLLPKNEKR--------DQANMPVM----EKSQ 1907
D E ED + E+Q E + L P+ K D+ + + E+ Q
Sbjct: 2394 DQEEEEIEDTLMDTEEQE-EFKAADVEQLKPEEIKSGTTAPLGFDEMEVEIQTVKTEEDQ 2452
Query: 1908 DDGSVKP-LGSANIDPESHLEDLISISRSYLGENTHKLSQLSVND--EELGKYHE---PC 1961
D + K + N PE E I + +L + + VN+ +EL + E P
Sbjct: 2453 DPRTDKAHKETENEKPERSRESTIHTAHQFLMDTIFQPFLKDVNELRQELERQLEMWQPR 2512
Query: 1962 DAPDHVKDNATA-LWRRYELSTTKLSQELTEQLRLVLEPTVASKLQGYYKTGKRIHMKKV 2020
++ + ++ A +W+ Y + T LSQ L E+LRL+L PT A+KL+G Y+TGKR++++KV
Sbjct: 2513 ESGNPEEEKVAAEMWQSYLILTAPLSQRLCEELRLILVPTQAAKLKGDYRTGKRLNIRKV 2572
Query: 2021 IQFIASYYRMDKIWLRRTRPNKRDYQVVIAVDDSHSMSESCCGDVAVEALVTVCRAVSQL 2080
I +IAS +R DKIWLRRT+P+KR YQ+ +A+DDS SM ++ +A E+L + A++ L
Sbjct: 2573 IPYIASQFRKDKIWLRRTKPSKRQYQICLAIDDSSSMVDNHTKQLAFESLAVIGNALTLL 2632
Query: 2081 EMGSLAVASFGTKGNINLLHDFDSPFTAESGVKVSRIYTSLVFFFIDISTVHLLNMLKGS 2140
E+G +AV SFG ++ LLH F F+ SG ++ R+
Sbjct: 2633 EVGQIAVCSFGE--SVKLLHPFHEQFSDYSGSQILRL----------------------- 2667
Query: 2141 DCSFLTEEQMVSNLTFKQENTIADEPVVDLLKFLTNKLDAAVVKARLPSGHNPLQQLVLI 2200
F+Q+ T + L+ + N AA ++ S QL+L+
Sbjct: 2668 -------------CKFQQKKT----KIAQFLESVANMFAAAQQLSQNISSETA--QLLLV 2708
Query: 2201 IADGR---FHEKDNLKRCVREALASNRMVAFLLLDN--SQESIMDLMEASFEG-GKM-KF 2253
++DGR K+ + V+ A +N V F++LDN S++SI+D+ F+G G+M +
Sbjct: 2709 VSDGRGLFLEGKERVLAAVQAARNANIFVIFVVLDNPSSRDSILDIKVPIFKGPGEMPEI 2768
Query: 2254 SKYMDSFPFPYYIVLRNIEALPRTLANLLRQ 2284
YM+ FPFPYYI+LR++ ALP TL++ LRQ
Sbjct: 2769 RSYMEEFPFPYYIILRDVNALPETLSDALRQ 2799
Score = 170 bits (431), Expect = 5e-40
Identities = 187/853 (21%), Positives = 335/853 (38%), Gaps = 120/853 (14%)
Query: 127 GCAWAHIGALRIHLLLSYNEVDPVMKYYCKYTQLEETISSLELEIQVRKECGYLSGQFLT 186
G W +G L+I L DP +K K ++E + L+ E + R LS Q T
Sbjct: 435 GSLWVSLGLLQIQTWLPQARFDPAVKREYKLNYVKEELHQLQCEWKTRN----LSSQLQT 490
Query: 187 ----------------VEADKRKAERLEKLQAELRKLQRKIVFRSESWKYKKLMNECDEF 230
V +++ +RL+ L L K Q FR + Y+ L+ E +
Sbjct: 491 GRDLEDEVVVSYSHPHVRLLRQRMDRLDNLTCHLLKKQ---AFRPQLPAYESLVQEIHHY 547
Query: 231 LKHIASLEVLV-------------GNVEAEDLQQVIDRTHSWQETAMCFINRLTDEYTAY 277
+ IA + G A+ Q ++ SWQ++ F RL++EYT Y
Sbjct: 548 VTSIAKAPAVQDLLTRLLQALHIDGPRSAQVAQSLLKEEASWQQSHHQFRKRLSEEYTFY 607
Query: 278 NDIIQPIQVAVYEMKFGLSLVLSSFLEKEYLRKVGHENINLVTDMIYILMRFPRAASW-- 335
D + P+Q ++ +++ G+ LV S + VG + + + L+ FP
Sbjct: 608 PDAVSPLQASILQLQHGMRLVASELHTSLHSSMVGADRLGTLATA---LLAFPSVGPTFP 664
Query: 336 KFISVEDVGVDLHSSYKLDFGTDFYLNMGLIERLITLSSGVSADKK-VSAMRCRASIYWN 394
+ + D + S L GL + ++ S G + K A R + N
Sbjct: 665 TYYAHADTLCSVKSEEVL---------RGLGKLILKRSGGKELEGKGQKACPTREQLLMN 715
Query: 395 ILVQIAYSIANAKIIDRESYMLLHKIFDEFASLWMSMKVYAKSKSDHDAQQFKFKPRAFQ 454
L+ + + +D+ + L + E S W + A+ K++ ++ ++++ R +
Sbjct: 716 ALLYLRSHVLCKGELDQRALQLFRHVCQEIISEWDEQERIAQEKAEQESGLYRYRSRNSR 775
Query: 455 IESIMELEIPALANSSATEAFSDWKEFSYEEKSADNMESSEECEILDEEWKH---LEESI 511
E E D+ + + +N +S+ E +E + L ++
Sbjct: 776 TALSEEEEEEREFRKQFPLHEKDFADILVQPTLEENKGTSDGQE--EEAGTNPALLSQNS 833
Query: 512 LDNVVLIHSQLF--GSGDLVQAPGIFEISDEDRLHSFSESYKLGINLIKGAHSSNLASLD 569
+ V+LIH QL + L + + L F Y+ G +L+ + L+
Sbjct: 834 MQAVMLIHQQLCLNFARSLWYQQTLPPHEAKHYLSLFLSCYQTGASLVTHFYPLMGVELN 893
Query: 570 AKLIPEHLFYLSIDYRRKFHSSS-----KSANRYNFYKDSNAHEIEQMLKVLAPLRQQIT 624
+L+ L ++ + F + K Y+FY+ N E Q VL + ++
Sbjct: 894 DRLLGSQLLACTLSHNTLFGEAPSDLMVKPDGPYDFYQHPNVPEARQCQPVLQGFSEAVS 953
Query: 625 SLLNEWEEQNDLQRFLDVIDMLLTLPSDIPLAKAFSGLQFLLHKAQVMQENHSK-FTFSN 683
LL +W E L++ L V+D + + P P++K +GL+ LL KAQ +EN S+ +
Sbjct: 954 HLLQDWPEHPALEQLLVVMDRIRSFPLSSPISKFLNGLEILLAKAQDWEENASRALSLRK 1013
Query: 684 QLKSVFDLMSSWHKMELGSWPVLLDEVMDQYENNAKKSVLSSSIHYF*SINFPKSNFYFS 743
L + ++ W K+EL W + LD M ++ + K H+F + +
Sbjct: 1014 HLDLISQMIIRWRKLELNCWSMSLDNTMKRHTEKSTK-------HWFSIYQMLEKHMQEQ 1066
Query: 744 YES-------------CSLEDFIQTSSFGEFRKRLQLLYAFLGQNHTSACLKINSSNIVF 790
E +L+ FI+ SS GEF RLQ+L F
Sbjct: 1067 TEEQEDDKQMTLMLLVSTLQAFIEGSSLGEFHVRLQMLLVF------------------- 1107
Query: 791 FLHCWTLQLLSDGAVNILVQYVWILCAVLTNHIDASRKEIL-------TELKDLVKLCRW 843
HC L + + L +W L D + +I+ ELK+ VK+ +W
Sbjct: 1108 --HCHVLLMPQVEGKDSLCSVLWNLYHYYKQFFDRVQAKIVELRSPLEKELKEFVKISKW 1165
Query: 844 EQDKSYSSIENLKKSRQKLKKLIKKHTDILQEPMDKLI--------RDVLHKGSISGVSD 895
+S ++++K+ + L K +KK +L EP + D L + + S+
Sbjct: 1166 NDVSFWSIKQSVEKTHRTLFKFMKKFEAVLSEPCRSSLVESDKEEQPDFLPRPTDGAASE 1225
Query: 896 LPLFSDENRLYQE 908
L + NR +E
Sbjct: 1226 LSSIQNLNRALRE 1238
Score = 56.2 bits (134), Expect = 1e-05
Identities = 74/335 (22%), Positives = 130/335 (38%), Gaps = 47/335 (14%)
Query: 1520 EDETPDDTGEKYESGPSVKDGDGSNKELRAKD-DSTSDQSGDDSCDE---------GDAQ 1569
E E D ++ + V+D +E +D DS SD G+D+ E D +
Sbjct: 1896 EGEGMKDVSDQIGNEEQVEDTFQKGQEKDKEDPDSKSDIKGEDNAIEMSEDFDGKMHDGE 1955
Query: 1570 NDEAAAQNEFDDEENGDDVNMDKEAAHSDATGLKPD--------EPDHSSDMEIDLNANE 1621
+E +E D E GD +DK D G + D + D D E + N E
Sbjct: 1956 LEEQEEDDEKSDSEGGD---LDKHM--GDLNGEEADKLDERLWGDDDEEEDEEEEDNKTE 2010
Query: 1622 DVDP-IEEGDQE--GHDDSAENGNQEDETCPPDEIMEEAHTEVDVSSE-KDDLGQEHQEN 1677
+ P ++E D E DD+ ++GN + D+ E+ E D + +D + ++ E
Sbjct: 2011 ETGPGMDEEDSELVAKDDNLDSGNSNKDKSQQDKKEEKEEAEADDGGQGEDKINEQIDER 2070
Query: 1678 D-DMNSMDPKNDTSESSDVVNPQVSNVDLASQSKSDLQ-TSGSENIASQSNLSNSHHDFG 1735
D D N +DP + E P+ +DL D + +G E+ ++ + +
Sbjct: 2071 DYDENEVDPYHGNQEKV----PEPEALDLPDDLNLDSEDKNGGEDTDNEEGEEENPLEIK 2126
Query: 1736 NPAVTGGFPSSDMSEMDINMSDSSNTGGFSKTQPKSHLPQHEHSFSQEK-QTNPSRSTGD 1794
G + + E + + ++S S +P+ + + + +E+ T GD
Sbjct: 2127 EKPEEAGHEAEERGETETDQNESQ-----SPQEPEEGPSEDDKAEGEEEMDTGADDQDGD 2181
Query: 1795 ALDFRKEKINVSGDLPEDNIEHHGEMDDNNADEYG 1829
A +E + + E D ADE G
Sbjct: 2182 AAQHPEEH--------SEEQQQSVEEKDKEADEEG 2208
>ref|XP_518639.1| PREDICTED: MDN1, midasin homolog [Pan troglodytes]
Length = 5369
Score = 259 bits (661), Expect = 1e-66
Identities = 255/963 (26%), Positives = 420/963 (43%), Gaps = 182/963 (18%)
Query: 1448 QKKEEQEESK-EVPGNDNTGIEMDQDF----------QADAVSL--------SEDSSENE 1488
+K++ +SK ++ G DN IEM +DF + D VSL S ++E
Sbjct: 4452 RKRQRNPDSKSDIKGEDNA-IEMSEDFDGKMHDGELEEQDWVSLEICLSSVPSLSEEDDE 4510
Query: 1489 DCDGENEELESEMGP-TGPDSEAVGEKIW---DQNEDETPDDTGEKYESGPSVKDGDGSN 1544
D E +L+ MG G +++ + E++W D+ EDE +D + E+GP + + D
Sbjct: 4511 KSDSEGGDLDKHMGDLNGEEADKLDERLWGDDDEEEDEEEEDNKTE-ETGPGMDEEDS-- 4567
Query: 1545 KELRAKDDSTSDQSGDDSCDEGDAQNDEAAAQNEFDDEENGDD-VNMDKEAAHSDATGLK 1603
EL AKDD+ SG+ + D+ E + E DD G+D +N + D +
Sbjct: 4568 -ELVAKDDNLD--SGNSNKDKSQQDKKEEKEEAEADDGGQGEDKINEQIDEREYDENEVD 4624
Query: 1604 P--------------DEPDHSSDMEIDLNANEDVDPIEEGDQE------------GH--- 1634
P D PD + D N ED D EEG++E GH
Sbjct: 4625 PYHGNQEKVPEPEALDLPDDLNLDSEDKNGGEDTDN-EEGEEENPLEIKEKPEEAGHEAE 4683
Query: 1635 -------DDSAENGNQEDETCPPDEIMEEAHTEVDVSSEKDDLG-----QEHQENDDMNS 1682
D + QE E P ++ E E+D ++ D +EH E +
Sbjct: 4684 ERGETETDQNESQSPQEPEEGPSEDDEAEGEEEMDTGADDQDGDAAQHPEEHSEEQQQSV 4743
Query: 1683 MDPKNDTSESSDVVNPQVSNVDLASQSKSDLQTSGSENIASQSNLSNSHHDFGNPAV--- 1739
+ + E P ++ Q + + + S +E ++ H G V
Sbjct: 4744 EEKDKEADEEGGENGP--ADQGFQPQEEEEREDSDTEEQVPEALERKEHASCGQTGVENM 4801
Query: 1740 --------TGGFPSSDMSE--------------------MDINMSDSSNTGGFSKTQPKS 1771
G P + + D N ++ + ++ +
Sbjct: 4802 QNTQAMELAGAAPEKEQGKEVISGFTAAASCLLEHGSGAADANQAEGHESNFIAQLASQK 4861
Query: 1772 HLPQHEHSFSQEK-QTNPSRSTGDALDFRKEKINV--SGDLPEDNIEHHGEMDDNNADEY 1828
H ++ SF ++ Q + RS GD + +++ + E + +AD +
Sbjct: 4862 HTRKNTQSFKRKPGQADNERSMGDHNERVHKRLRTVDTDSHAEQGPAQQPQAQVEDADAF 4921
Query: 1829 GYVSEFEKG-TTQALGPATLEQVDRNIDVDKVDTESRAGEDANLQLEKQNSEIDSVSNSS 1887
++ + Q A+ EQ D K D E ED + E+Q E +
Sbjct: 4922 EHIKQGSDAYDAQTYDVASKEQQQSAKDSGK-DQEEEEIEDTLMDTEEQE-EFKAADVEQ 4979
Query: 1888 LLPKNEKR--------DQANMPVM----EKSQDDGSVKP-LGSANIDPESHLEDLISISR 1934
L P+ K D+ + + E+ QD + K + N PE E I +
Sbjct: 4980 LKPEEIKSGTTAPLGFDEMEVEIQTVKTEEDQDPRTDKAHKETENEKPERSRESTIHTAH 5039
Query: 1935 SYLGENTHKLSQLSVND--EELGKYHE---PCDAPDHVKDNATA-LWRRYELSTTKLSQE 1988
+L + + VN+ +EL + E P ++ + ++ A +W+ Y + T LSQ
Sbjct: 5040 QFLMDTIFQPFLKDVNELRQELERQLEMWQPRESGNPEEEKVAAEMWQSYLILTAPLSQR 5099
Query: 1989 LTEQLRLVLEPTVASKLQGYYKTGKRIHMKKVIQFIASYYRMDKIWLRRTRPNKRDYQVV 2048
L E+LRL+LEPT A+KL+G Y+TGKR++++KVI +IAS +R DKIWLRRT+P+KR YQ+
Sbjct: 5100 LCEELRLILEPTQAAKLKGDYRTGKRLNIRKVIPYIASQFRKDKIWLRRTKPSKRQYQIC 5159
Query: 2049 IAVDDSHSMSESCCGDVAVEALVTVCRAVSQLEMGSLAVASFGTKGNINLLHDFDSPFTA 2108
+A+DDS SM ++ +A E+L + A++ LE+G +AV SFG ++ LLH F F+
Sbjct: 5160 LAIDDSSSMVDNHTKQLAFESLAVIGNALTLLEVGQIAVCSFGE--SVKLLHPFHEQFSD 5217
Query: 2109 ESGVKVSRIYTSLVFFFIDISTVHLLNMLKGSDCSFLTEEQMVSNLTFKQENTIADEPVV 2168
SG ++ R+ F+Q+ T +
Sbjct: 5218 YSGSQILRL------------------------------------CKFQQKKT----KIA 5237
Query: 2169 DLLKFLTNKLDAAVVKARLPSGHNPLQQLVLIIADGR---FHEKDNLKRCVREALASNRM 2225
L+ + N AA ++ S QL+L+++DGR K+ + V+ A +N
Sbjct: 5238 QFLESVANMFAAAQQLSQNISSETA--QLLLVVSDGRGLFLEGKERVLAAVQAARNANIF 5295
Query: 2226 VAFLLLDN--SQESIMDLMEASFEG-GKM-KFSKYMDSFPFPYYIVLRNIEALPRTLANL 2281
V F++LDN S++SI+D+ F+G G+M + YM+ FPFPYYI+LR++ ALP TL++
Sbjct: 5296 VIFVVLDNPSSRDSILDIKVPIFKGPGEMPEIRSYMEEFPFPYYIILRDVNALPETLSDA 5355
Query: 2282 LRQ 2284
LRQ
Sbjct: 5356 LRQ 5358
Score = 158 bits (399), Expect = 2e-36
Identities = 161/733 (21%), Positives = 296/733 (39%), Gaps = 92/733 (12%)
Query: 191 KRKAERLEKLQAELRKLQRKIVFRSESWKYKKLMNECDEFLKHIASLEVLV--------- 241
+++ +RL+ L L K Q FR + Y+ L+ E ++ IA +
Sbjct: 3028 RQRMDRLDNLTCHLLKKQ---AFRPQLPAYESLVQEIHHYVTSIAKAPAVQDLLTRLLQA 3084
Query: 242 ----GNVEAEDLQQVIDRTHSWQETAMCFINRLTDEYTAYNDIIQPIQVAVYEMKFGLSL 297
G A+ Q ++ SWQ++ F RL++EYT Y D + P+Q ++ +++ G+ L
Sbjct: 3085 LHMDGPRSAQVAQSLLKEEASWQQSHHQFRKRLSEEYTFYPDAVSPLQASILQLQHGMRL 3144
Query: 298 VLSSFLEKEYLRKVGHENINLVTDMIYILMRFPRAASW--KFISVEDVGVDLHSSYKLDF 355
V S + VG + + + L+ FP + + D + S L
Sbjct: 3145 VASELHTSLHSSMVGADRLGTLATA---LLAFPSVGPTFPTYYAHADTLCSVKSEEVL-- 3199
Query: 356 GTDFYLNMGLIERLITLSSGVSADKK-VSAMRCRASIYWNILVQIAYSIANAKIIDRESY 414
GL + ++ S G + K A R + N L+ + + +D+ +
Sbjct: 3200 -------RGLGKLILKRSGGKELEGKGQKACPTREQLLMNALLYLRSHVLCKGELDQRAL 3252
Query: 415 MLLHKIFDEFASLWMSMKVYAKSKSDHDAQQFKFKPRAFQIESIMELEIPALANSSATEA 474
L + E S W + A+ K++ ++ ++++ R + E E
Sbjct: 3253 QLFRHVCQEIISEWDEQERIAQEKAEQESSLYRYRSRNSRTALSEEEEEEREFRKQFPLH 3312
Query: 475 FSDWKEFSYEEKSADNMESSEECEILDEEWKH---LEESILDNVVLIHSQLF--GSGDLV 529
D+ + + + +N +S+ E +E + L ++ + V+LIH QL + L
Sbjct: 3313 EKDFADILVQPELEENKGTSDGQE--EEAGTNPALLSQNSMQAVMLIHQQLCLNFARSLW 3370
Query: 530 QAPGIFEISDEDRLHSFSESYKLGINLIKGAHSSNLASLDAKLIPEHLFYLSIDYRRKFH 589
+ + L F Y+ G +L+ + L+ +L+ L ++ + F
Sbjct: 3371 YQQTLPPHEAKHYLSLFLSCYQTGASLVTHFYPLMGVELNDRLLGSQLLACTLSHNTLFG 3430
Query: 590 SSS-----KSANRYNFYKDSNAHEIEQMLKVLAPLRQQITSLLNEWEEQNDLQRFLDVID 644
+ K Y+FY+ N E Q VL + ++ LL +W E L++ L V+D
Sbjct: 3431 EAPSDLMVKPDGPYDFYQHPNVPEARQCQPVLQGFSEAVSHLLQDWPEHPALEQLLVVMD 3490
Query: 645 MLLTLPSDIPLAKAFSGLQFLLHKAQVMQENHSK-FTFSNQLKSVFDLMSSWHKMELGSW 703
+ + P P++K +GL+ LL KAQ +EN S+ + L + ++ W K+EL W
Sbjct: 3491 RIRSFPLSSPISKFLNGLEILLAKAQDWEENASRVLSLRKHLDLISQMIIRWRKLELNCW 3550
Query: 704 PVLLDEVMDQYENNAKKSVLSSSIHYF*SINFPKSNFYFSYES-------------CSLE 750
+ LD M ++ + K H+F + + E +L+
Sbjct: 3551 SMSLDNTMKRHTEKSTK-------HWFSIYQMLEKHMQEQTEEQEDDKQMTLMLLVSTLQ 3603
Query: 751 DFIQTSSFGEFRKRLQLLYAFLGQNHTSACLKINSSNIVFFLHCWTLQLLSDGAVNILVQ 810
FI+ SS GEF RLQ+L F HC L + + L
Sbjct: 3604 AFIEGSSLGEFHVRLQMLLVF---------------------HCHVLLMPQVEGKDSLCS 3642
Query: 811 YVWILCAVLTNHIDASRKEIL-------TELKDLVKLCRWEQDKSYSSIENLKKSRQKLK 863
+W L D + +I+ ELK+ VK+ +W +S ++++K+ + L
Sbjct: 3643 VLWNLYHYYKQFFDRVQAKIVELRSPLEKELKEFVKISKWNDVSFWSIKQSVEKTHRTLF 3702
Query: 864 KLIKKHTDILQEP 876
K +KK +L EP
Sbjct: 3703 KFMKKFEAVLSEP 3715
>ref|XP_594023.1| PREDICTED: similar to Midasin (MIDAS-containing protein), partial
[Bos taurus]
Length = 1831
Score = 241 bits (616), Expect = 2e-61
Identities = 229/878 (26%), Positives = 387/878 (43%), Gaps = 146/878 (16%)
Query: 1450 KEEQEESKEVPGNDNTGIEMDQDFQADAVS--LSEDSSENEDCDGENEELESEMGP-TGP 1506
KE+ + ++ G DN IEM +DF L E ++E D E +L+ +MG G
Sbjct: 1002 KEDPDSKSDIKGEDNA-IEMSEDFDGKMHDGELEEQEEDDEKSDSETGDLDKQMGDLNGE 1060
Query: 1507 DSEAVGEKIWDQNEDETPDDTGEKYE-SGPSVKDGDG-------------SNKELRAKDD 1552
+++ + E++W ++DE ++ K E +GP + + D SN+E + + D
Sbjct: 1061 EADKLDERLWGDDDDEEDEEEDSKTEETGPGMDEEDSELVAKDDNLDAGKSNRE-KTRQD 1119
Query: 1553 STSDQSGDDSCDEGDAQN--DEAAAQNEFDDEE----NGDDVNMDKEAAHSDATGLKPDE 1606
++ ++ D+G Q+ +E + E+D+ E +G++ + + A L D
Sbjct: 1120 KKEEKEEAEADDDGRGQDKINEQIDEREYDENEVDPYHGNEEKLPEPEALDLPDDLNLDS 1179
Query: 1607 PDHSSDMEIDLNANEDVDPIE------EGDQEGHDDSAENGNQEDETCPP---------- 1650
D D + D E+ +P+E + ++ GH+ AE+ N+E E
Sbjct: 1180 EDKDGDGDTDHEDGEEENPLEIKEQPKDTEEAGHE--AEDINEETEADQDEGQAQPQPEG 1237
Query: 1651 ----DEIMEEAHTEVDVSSEKDDL-GQEHQENDD----MNSMDPKNDTSESS-DVVNPQV 1700
D+ EE E+D ++ D EH E D ++S D DTSE S + P
Sbjct: 1238 GHSEDDKGEEGEEEMDTGADDGDQDAAEHPEEDTEEAPLSSEDKDKDTSEESPEKDTPLD 1297
Query: 1701 SNVDLASQSKSDLQTSGSENIASQSNLSNSHHDFGNPAV-----------TGGFPSSDMS 1749
+ +Q K + ++S E + H G + G P +
Sbjct: 1298 QGLQPQTQEKEEGESSDMEEPVPEPTERKEHESCGQTGLESVQSEQAVELAGAAPEKEQG 1357
Query: 1750 E-------MDINMSDSSNTGGFSKTQPKSHLPQHEHSFSQEK-QTNPSRSTGD---ALDF 1798
D N ++ + ++ + H ++ SF ++ Q + RS GD +
Sbjct: 1358 REEHGSGAADANQAEGHESSFMARMASQKHTRKNTQSFKRKPGQADNERSLGDHSERVHK 1417
Query: 1799 RKEKINVSGDLPEDNIEHHGEMDDNNADEYGYVSEFEKGTTQALGPATLEQVDRNIDVDK 1858
R ++ +D + + +D A E+ E Q A+ EQ D K
Sbjct: 1418 RLRTMDTESRAEQDPAQPQAQAEDAEAFEH-IKQGSEPYDAQTYDVASTEQQQSAKDSSK 1476
Query: 1859 VDTESRAGEDANLQLEKQNSEIDSVSNSSLLPKNEKRDQANMPVME---------KSQDD 1909
E ED ++ E+Q E+ +V L P+ K P E K+++D
Sbjct: 1477 AHEEEEV-EDTSVDPEEQE-ELRAVDTEPLKPEEVKSGSTAQPGSEEMEMETQTVKTEED 1534
Query: 1910 GSVKPLGS----ANIDPESHLEDLISISRSYLGENTHKLSQLSVND--EELGKYHE---P 1960
+ S N PE + I + L + + VN+ +EL + E P
Sbjct: 1535 QHPRTDPSHEETENEKPERSRDSTIHTAHQLLVDTIFQPFLKDVNELRQELERQLETWQP 1594
Query: 1961 CDAPDHVKDNATA-LWRRYELSTTKLSQELTEQLRLVLEPTVASKLQGYYKTGKRIHMKK 2019
++ + ++ A A +W+ Y + T LSQ+L EQLRL+LEPT A+KL+G Y+TGKR++M+K
Sbjct: 1595 HESGNPEEEKAAAEMWQSYLVLTAPLSQQLCEQLRLILEPTQAAKLKGDYRTGKRLNMRK 1654
Query: 2020 VIQFIASYYRMDKIWLRRTRPNKRDYQVVIAVDDSHSMSESCCGDVAVEALVTVCRAVSQ 2079
VI +IAS +R DKIWLRRT+P+KR YQ+ +A+DDS SM ++ +A E+L + A++
Sbjct: 1655 VIPYIASQFRKDKIWLRRTKPSKRQYQICLAIDDSSSMVDNHTKQLAFESLAVIGNALTL 1714
Query: 2080 LEMGSLAVASFGTKGNINLLHDFDSPFTAESGVKVSRIYTSLVFFFIDISTVHLLNMLKG 2139
LE+G +AV SFG ++ LLH F F+ SG ++ R+
Sbjct: 1715 LEVGQIAVCSFGE--SVKLLHPFHEQFSDYSGSQILRL---------------------- 1750
Query: 2140 SDCSFLTEEQMVSNLTFKQENTIADEPVVDLLKFLTNKLDAAVVKARLPSGHNP-LQQLV 2198
F+Q+ T + L+ + N AA +L +P + QL+
Sbjct: 1751 --------------CKFQQKKT----KIAQFLESVANMFAAA---QQLSQNVSPEIAQLL 1789
Query: 2199 LIIADGR---FHEKDNLKRCVREALASNRMVAFLLLDN 2233
L+++DGR KD + V+ A +N V F++LDN
Sbjct: 1790 LVVSDGRGLFLEGKDRVLAAVQAARNANIFVIFVVLDN 1827
Score = 89.7 bits (221), Expect = 1e-15
Identities = 109/484 (22%), Positives = 183/484 (37%), Gaps = 76/484 (15%)
Query: 423 EFASLWMSMKVYAKSKSDHDAQQFKFKPRAFQIESIMELEIPALANSSATEAFSDWKEFS 482
E + W + A+ K++ ++ ++++ R + E E S D+ +
Sbjct: 1 EIINEWDEQERIAQEKAEQESSLYRYRGRTPRTALSEEEEEERAFRSQFPLHEKDFADIL 60
Query: 483 YEEKSADNMESSEECEILDEEWKHLEESILDNVVLIHSQL-FGSGDLV---QAPGIFEIS 538
E + S + E L +S + V+ IH QL G + Q+P
Sbjct: 61 VEPTLEEKGPSGGQEEEATPGPAVLSQSSMQAVMRIHQQLCLGFARSLWYQQSPPPH--G 118
Query: 539 DEDRLHSFSESYKLGINLIKGAHSSNLASLDAKLIPEHLFYLSIDYRRKFHSSS-----K 593
E L F Y+ G +L+ + L+ +L+ L ++ + F + K
Sbjct: 119 TEHYLSLFLSCYQTGASLVTHFYPLMGVELNDQLLGSQLLACTLSHNTLFGEVTSDLMVK 178
Query: 594 SANRYNFYKDSNAHEIEQMLKVLAPLRQQITSLLNEWEEQNDLQRFLDVIDMLLTLPSDI 653
Y+FY N E VL Q + L V+D + + P
Sbjct: 179 PDGPYDFYHHPNIPEARHCQPVL----------------QGFSEALLVVMDRICSFPLSS 222
Query: 654 PLAKAFSGLQFLLHKAQVMQENHSK-FTFSNQLKSVFDLMSSWHKMELGSWPVLLDEVMD 712
P++K +GL+ LL KAQ +EN S+ + L V L+ W K+EL W + LD M
Sbjct: 223 PISKFLNGLEILLAKAQDWEENASRALSLRKHLDLVSQLIIRWRKLELNCWSMSLDNTMK 282
Query: 713 QYENNAKKSVLSSSIHYF*SINFPKSNFYFSYES-------------CSLEDFIQTSSFG 759
++ + K H+F + + E +L+ FI+ SS G
Sbjct: 283 RHTEKSTK-------HWFSIYQMLEKHMQEQTEEQEDDKQMTLMLLVSTLQAFIEGSSLG 335
Query: 760 EFRKRLQLLYAFLGQNHTSACLKINSSNIVFFLHCWTLQLLSDGAVNILVQYVWILCAVL 819
EF RLQ+L F HC L + + L +W L
Sbjct: 336 EFHIRLQMLLVF---------------------HCHVLLMPQVEGKDALCSVLWNLYHYY 374
Query: 820 T---NHIDAS----RKEILTELKDLVKLCRWEQDKSYSSIENLKKSRQKLKKLIKKHTDI 872
N + A R + ELK+ VK+ +W +S ++++K+ + L K +KK +
Sbjct: 375 KQFFNRVQAKIVELRSPLEKELKEFVKISKWNDVSFWSIKQSVEKTHRTLFKFMKKFEAV 434
Query: 873 LQEP 876
L EP
Sbjct: 435 LSEP 438
Score = 48.9 bits (115), Expect = 0.002
Identities = 100/456 (21%), Positives = 173/456 (37%), Gaps = 54/456 (11%)
Query: 1480 LSEDSSENEDCDGENEELESEMGPTGPDSEAVGEK-IWDQNEDETPDDTGEKYESGPSVK 1538
L ++ E+ +G E + E G G E G K + DQ E+E + + ++ G
Sbjct: 947 LPKEFMEDSAGEGATEFHDYEGGGIG---EGEGMKDVSDQIENE--EQAEDTFQKGQEKD 1001
Query: 1539 DGDGSNKELRAKDDSTSDQSGDDSCDEGDAQNDEAAAQNEFDDEENGDDVNMDKEAAHSD 1598
D +K +D+ + S D D + +E +E D E GD +DK+ D
Sbjct: 1002 KEDPDSKSDIKGEDNAIEMSEDFDGKMHDGELEEQEEDDEKSDSETGD---LDKQM--GD 1056
Query: 1599 ATGLKPD--------EPDHSSDMEIDLNANEDVDPIEEGDQE--GHDDSAENGNQEDETC 1648
G + D + D D E D E ++E D E DD+ + G E
Sbjct: 1057 LNGEEADKLDERLWGDDDDEEDEEEDSKTEETGPGMDEEDSELVAKDDNLDAGKSNREKT 1116
Query: 1649 PPDEIMEEAHTEVDVSSE-KDDLGQEHQEND-DMNSMDPKNDTSESSDVVNPQVSNVDLA 1706
D+ E+ E D +D + ++ E + D N +DP + E P+ +DL
Sbjct: 1117 RQDKKEEKEEAEADDDGRGQDKINEQIDEREYDENEVDPYHGNEEKL----PEPEALDLP 1172
Query: 1707 SQSKSDLQTSGSENIASQSNLSNSHHDFGNPAVTGGFPSSDMSEM-----DIN-MSDSSN 1760
D SE+ + + + NP P D E DIN +++
Sbjct: 1173 DDLNLD-----SEDKDGDGDTDHEDGEEENPLEIKEQP-KDTEEAGHEAEDINEETEADQ 1226
Query: 1761 TGGFSKTQPKSHLPQHEHSFSQEKQTNPSRSTGDALDFRKEKINVSGDLPEDNIEHHGEM 1820
G ++ QP+ + + E++ + GD + + ED E
Sbjct: 1227 DEGQAQPQPEGGHSEDDKGEEGEEEMDTGADDGDQ--------DAAEHPEEDTEEAPLSS 1278
Query: 1821 DDNNADEYGYVSEFEKGTTQALGPATLEQVD-RNIDVDK---VDTESRAGED-ANLQLEK 1875
+D + D E + Q L P T E+ + + D+++ TE + E LE
Sbjct: 1279 EDKDKDTSEESPEKDTPLDQGLQPQTQEKEEGESSDMEEPVPEPTERKEHESCGQTGLES 1338
Query: 1876 QNSEIDSVSNSSLLPKNEK-RDQANMPVMEKSQDDG 1910
SE +V + P+ E+ R++ + +Q +G
Sbjct: 1339 VQSE-QAVELAGAAPEKEQGREEHGSGAADANQAEG 1373
Score = 46.2 bits (108), Expect = 0.013
Identities = 55/272 (20%), Positives = 102/272 (37%), Gaps = 27/272 (9%)
Query: 1448 QKKEEQEESKEVPGNDNTGIEMDQDFQADAVSLSEDSSENEDCDGENEELESEMGPTGPD 1507
+ K+ ++ G + +E+ + + + E NE+ + + +E +++ P G
Sbjct: 1180 EDKDGDGDTDHEDGEEENPLEIKEQPKDTEEAGHEAEDINEETEADQDEGQAQPQPEGGH 1239
Query: 1508 SE----AVGEKIWDQNEDETPDDTGEKYESGPSVKDGDGSNKELRAKDDSTSDQSGDDSC 1563
SE GE+ D D+ D E E +K+ KD S D
Sbjct: 1240 SEDDKGEEGEEEMDTGADDGDQDAAEHPEEDTEEAPLSSEDKD---KDTSEESPEKDTPL 1296
Query: 1564 DEG-DAQNDEAAAQNEFDDEENGDDVNMDKEAAHSDATGLKPDEPDHSSDMEIDLNANED 1622
D+G Q E D EE + KE TGL+ + + + ++
Sbjct: 1297 DQGLQPQTQEKEEGESSDMEEPVPEPTERKEHESCGQTGLESVQSEQAVEL-------AG 1349
Query: 1623 VDPIEEGDQEGHDDSAENGNQED--ETCPPDEIMEEAHTEVDVSSEKDDLGQEHQENDDM 1680
P +E +E H A + NQ + E+ + + HT + S K GQ
Sbjct: 1350 AAPEKEQGREEHGSGAADANQAEGHESSFMARMASQKHTRKNTQSFKRKPGQ-------- 1401
Query: 1681 NSMDPKNDTSESSDVVNPQVSNVDLASQSKSD 1712
D + + S+ V+ ++ +D S+++ D
Sbjct: 1402 --ADNERSLGDHSERVHKRLRTMDTESRAEQD 1431
Database: nr
Posted date: Jul 5, 2005 12:34 AM
Number of letters in database: 863,360,394
Number of sequences in database: 2,540,612
Lambda K H
0.319 0.133 0.385
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 3,757,054,071
Number of Sequences: 2540612
Number of extensions: 159489516
Number of successful extensions: 737845
Number of sequences better than 10.0: 7389
Number of HSP's better than 10.0 without gapping: 1011
Number of HSP's successfully gapped in prelim test: 6897
Number of HSP's that attempted gapping in prelim test: 595263
Number of HSP's gapped (non-prelim): 49923
length of query: 2332
length of database: 863,360,394
effective HSP length: 144
effective length of query: 2188
effective length of database: 497,512,266
effective search space: 1088556838008
effective search space used: 1088556838008
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 84 (37.0 bits)
Medicago: description of AC148398.1