BLAST2 result
BLASTP 2.2.2 [Dec-14-2001]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= AC146573.11 + phase: 2 /pseudo
(1025 letters)
Database: nr
2,540,612 sequences; 863,360,394 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gb|AAF75815.1| Contains similarity to DNA-directed RNA Polymeras... 811 0.0
emb|CAD41657.3| OSJNBa0019K04.4 [Oryza sativa (japonica cultivar... 307 1e-81
gb|AAX12374.1| DNA-directed RNA polymerase alpha subunit [Spinac... 224 9e-57
gb|AAS64314.1| DNA-dependent RNA polymerase II largest subunit [... 162 7e-38
emb|CAC33863.1| RNA polymerase II largest subunit [Pleistophora ... 160 3e-37
gb|AAF36438.2| RNA polymerase II largest subunit [Leishmania don... 159 5e-37
gb|AAK97604.2| RNA polymerase II largest subunit [Trypanosoma cr... 157 2e-36
gb|AAW51135.1| RNA polymerase II largest subunit [Calostoma cinn... 156 3e-36
gb|AAN17722.1| RNA polymerase II largest subunit [Trypanosoma cr... 156 4e-36
gb|AAM45151.1| RNA polymerase II largest subunit [Naegleria grub... 155 5e-36
gb|AAS52006.1| ADR086Cp [Ashbya gossypii ATCC 10895] gi|45187959... 155 7e-36
gb|AAK15346.1| RNA polymerase II largest subunit [Leptomonas sey... 155 7e-36
gb|AAK00312.1| DNA-dependent RNA polymerase II largest subunit R... 154 1e-35
gb|AAC47792.2| RNA polymerase II large subunit [Leishmania major] 153 2e-35
gb|AAA50229.1| RNA polymerase II, largest subunit 151 1e-34
gb|AAC03137.3| RNA polymerase II largest subunit [Mastigoproctus... 150 3e-34
gb|AAF26656.2| RNA polymerase II largest subunit [Scolopendra po... 150 3e-34
emb|CAG98018.1| unnamed protein product [Kluyveromyces lactis NR... 149 4e-34
gb|AAF26651.2| RNA polymerase II largest subunit [Polyxenus fasc... 149 6e-34
gb|AAA50227.1| RNA polymerase II, largest subunit 149 6e-34
>gb|AAF75815.1| Contains similarity to DNA-directed RNA Polymerase alpha-subunit from
Methanococcus jannaschii gi|3915860 and contains
Ribosomal protein L36 PF|00444 and RNA-Polymerase
alpha-subunit PF|00623 domains. EST gb|AA597311 comes
from this gene. [Arabidopsis thaliana]
gi|30696792|ref|NP_176490.2| DNA-directed RNA polymerase
alpha subunit family protein [Arabidopsis thaliana]
gi|59939208|gb|AAX12372.1| DNA-directed RNA polymerase
beta subunit [Arabidopsis thaliana]
gi|12323252|gb|AAG51604.1| RNA polymerase IIA largest
subunit, putative; 12353-6556 [Arabidopsis thaliana]
gi|25404390|pir||D96655 hypothetical protein F16M19.19
[imported] - Arabidopsis thaliana
Length = 1453
Score = 811 bits (2096), Expect = 0.0
Identities = 426/757 (56%), Positives = 556/757 (73%), Gaps = 13/757 (1%)
Query: 272 LELSEIGIPCQIAEALQVSEYVNRQNRQNLLYCCELRLLEKGQINVRRNGNPVVLYKKED 331
L+L+EIGIP IA+ LQVSE++N+ N++ L+ LL+ +++VRR G+ +V + D
Sbjct: 332 LKLNEIGIPESIAKRLQVSEHLNQCNKERLVTSFVPTLLDNKEMHVRR-GDRLVAIQVND 390
Query: 332 LQIGDIFYRPLVDGDKVLINRPPSIHQHSMIALTVRVLPISSVVSINPICCSPLRGDFDG 391
LQ GD +R L+DGD VL+NRPPSIHQHS+IA+TVR+LP +SVVS+NPICC P RGDFDG
Sbjct: 391 LQTGDKIFRSLMDGDTVLMNRPPSIHQHSLIAMTVRILPTTSVVSLNPICCLPFRGDFDG 450
Query: 392 DCLHGYIPQSVGARVELNELVALDRQLINGQSGGNLLSLSQDSLTAAHLL-LEDGVGFNI 450
DCLHGY+PQS+ A+VEL+ELVALD+QLIN Q+G NLLSL QDSLTAA+L+ +E N
Sbjct: 451 DCLHGYVPQSIQAKVELDELVALDKQLINRQNGRNLLSLGQDSLTAAYLVNVEKNCYLNR 510
Query: 451 YQVQQLEMLCNKELTSPAIFKA-PSSNTPFWSGKQLFSMLLPSKFDYAFPSNDVFVKDGE 509
Q+QQL+M C +L PAI KA PSS P W+G QLF ML P FDY +P N+V V +GE
Sbjct: 511 AQMQQLQMYCPFQLPPPAIIKASPSSTEPQWTGMQLFGMLFPPGFDYTYPLNNVVVSNGE 570
Query: 510 LISCSESSGWLRDSENNVFQSLVEHFQGKILDVLHGAQKALCEWLSMTGFSVSLSDLYLS 569
L+S SE S WLRD E N + L++H +GK+LD+++ AQ+ L +WL M G SVSL+DLYLS
Sbjct: 571 LLSFSEGSAWLRDGEGNFIERLLKHDKGKVLDIIYSAQEMLSQWLLMRGLSVSLADLYLS 630
Query: 570 SDSYARKNMMEEISYGLRVAEQACDFNQLLVDHYSDFLSASPEENEKFVTVDVDRLNHER 629
SD +RKN+ EEISYGLR AEQ C+ QL+V+ + DFL+ + E+ E+ D+ R +ER
Sbjct: 631 SDLQSRKNLTEEISYGLREAEQVCNKQQLMVESWRDFLAVNGEDKEEDSVSDLARFCYER 690
Query: 630 QISAAQSQASVDAFRHVFRNIQSLADKHACKDNSFLAMFKAGSKGNLLKLVQHSMCLGLQ 689
Q SA S+ +V AF+ +R++Q+LA ++ + NSFL M KAGSKGN+ KLVQHSMC+GLQ
Sbjct: 691 QKSATLSELAVSAFKDAYRDVQALAYRYGDQSNSFLIMSKAGSKGNIGKLVQHSMCIGLQ 750
Query: 690 HSLVRLSYRIPRELSCAGWNSQKGLHSMEMSSDTLEPKQSYIAHAVVESSFLTGLNPLEC 749
+S V LS+ PREL+CA WN D+ +SY+ + V+E+SFLTGLNPLE
Sbjct: 751 NSAVSLSFGFPRELTCAAWNDPNSPLRGAKGKDS-TTTESYVPYGVIENSFLTGLNPLES 809
Query: 750 FVHSVTNRDSSFSDNADLPGTLTRRLMFFMRDMYDAYDGTVRNLYGNQLIQFSYDAEEDS 809
FVHSVT+RDSSFS NADLPGTL+RRLMFFMRD+Y AYDGTVRN +GNQL+QF+Y+ +
Sbjct: 810 FVHSVTSRDSSFSGNADLPGTLSRRLMFFMRDIYAAYDGTVRNSFGNQLVQFTYETDGPV 869
Query: 810 SCDSYFREDIIGGEPVGALSACAVSEAAYSALSQPISLLEASPLLNLKNVLECGSRKKGG 869
EDI GE +G+LSACA+SEAAYSAL QPISLLE SPLLNLKNVLECGS+K
Sbjct: 870 -------EDIT-GEALGSLSACALSEAAYSALDQPISLLETSPLLNLKNVLECGSKKGQR 921
Query: 870 DQTVSLFLSEKIGKQRNGFEYAALEVKNYLERYMFSNIVSTVMIIFTPQHCSQVKYSPWV 929
+QT+SL+LSE + K+++GFEY +LE+KN+LE+ FS IVST MIIF+P ++V SPWV
Sbjct: 922 EQTMSLYLSEYLSKKKHGFEYGSLEIKNHLEKLSFSEIVSTSMIIFSPSSNTKVPLSPWV 981
Query: 930 CHFHLDKENVTRRKLEVHSIIDSLYQQYDSFRRESKVILPSLKISSNEGGETSVGNEKDG 989
CHFH+ ++ + R++L S++ SL +QY S RE K+ + L I + + KD
Sbjct: 982 CHFHISEKVLKRKQLSAESVVSSLNEQYKSRNRELKLDIVDLDIQNTNHCSSDDQAMKDD 1041
Query: 990 EDCITVAVVEDSKNSV-QLDSVRKSLIPFLLQTAIKG 1025
CITV VVE SK+SV +LD++R LIPFLL + +KG
Sbjct: 1042 NVCITVTVVEASKHSVLELDAIRLVLIPFLLDSPVKG 1078
Score = 107 bits (267), Expect = 2e-21
Identities = 47/79 (59%), Positives = 60/79 (75%)
Query: 27 QEKISALEINAPGQVTCSDLGLPNSSYGCTTCGSKDRKSCEGHFGAIKFPFTILHPYFMA 86
++K+S LE+ AP QVT S LGLPN C TCGSKDRK CEGHFG I F ++I++PYF+
Sbjct: 28 RDKMSVLEVEAPNQVTDSRLGLPNPDSVCRTCGSKDRKVCEGHFGVINFAYSIINPYFLK 87
Query: 87 EIAEILQKICPACKSIRQE 105
E+A +L KICP CK IR++
Sbjct: 88 EVAALLNKICPGCKYIRKK 106
>emb|CAD41657.3| OSJNBa0019K04.4 [Oryza sativa (japonica cultivar-group)]
gi|50928085|ref|XP_473570.1| OSJNBa0019K04.4 [Oryza
sativa (japonica cultivar-group)]
Length = 1664
Score = 307 bits (786), Expect = 1e-81
Identities = 181/484 (37%), Positives = 274/484 (56%), Gaps = 60/484 (12%)
Query: 564 SDLYLSSDSYARKNMMEEISYGLRVAEQACDFNQLLVDHYSDFLSASPEENEKFVTVDVD 623
+DLYL SD Y+R+ + EE+ L AE+A Q+L++ S N K+ D
Sbjct: 538 TDLYLFSDHYSRRKLSEEVHLALDEAEEAFQIKQILLNSVSI-------PNLKYYDGGDD 590
Query: 624 RLNHERQ-----ISAAQSQASVDAFRHVFRNIQSLADKHACKDNSFLAMFKAGSKGNLLK 678
R N + Q +S ++S+ +F+ VF ++ + ++ KDNS + M +GSKG++LK
Sbjct: 591 RSNTDEQSGFTQVSLPIIRSSMTSFKSVFNDLLKMVQQYVSKDNSMMTMINSGSKGSVLK 650
Query: 679 LVQHSMCLGLQHSLVRLSYRIPRELSCAGWNSQKGLHSMEMSSDTLEPKQSYIAHAVVES 738
VQ + C+GLQ + +RIP +LSC WN K + E++ T E +AVV +
Sbjct: 651 FVQQTACVGLQLPASKFPFRIPSQLSCVSWNRHKS-RNCEITDGTSECVGGQDMYAVVRN 709
Query: 739 SFLTGLNPLECFVHSVTNRDSSFSDNADLPGTLTRRLMFFMRDMYDAYDGTVRNLYGNQL 798
SFL GLNPLEC +H+++ R + FS+NAD+PGTLTR+LM+ +RD Y AYDGTVR+ YG Q+
Sbjct: 710 SFLDGLNPLECLLHAISGRANFFSENADVPGTLTRKLMYHLRDTYVAYDGTVRSSYGQQI 769
Query: 799 IQFSYDAEEDSSCDSYFREDIIG--GEPVGALSACAVSEAAYSALSQPISLLEASPLLNL 856
++FSYD + Y D+ G G PVG+ +AC++SEAAY AL P++ LE SPL+NL
Sbjct: 770 VRFSYDTAD----GMYSDHDLEGEPGAPVGSWAACSISEAAYGALDHPVNSLEDSPLMNL 825
Query: 857 KNVLECGSRKKGGDQTVSLFLSEKIGKQRNGFEYAALEVKNYLERYMFSNIVSTVMIIFT 916
+ VL+C D T LFLS+ + K R GFEYA+LEVK++LER FS++V
Sbjct: 826 QEVLKCHKGTNSLDHTGLLFLSKHLRKYRYGFEYASLEVKDHLERVDFSDMV-------- 877
Query: 917 PQHCSQVKYSPWVCHFHLDKENVTRRKLEVHSIIDSLYQQYDSFRRESKVILPSLKISSN 976
D E + ++L + I+ + QY++ R++ +PS+ IS++
Sbjct: 878 ------------------DTETMKIKRLRLEFIVREIIDQYNTLRKQLNNAIPSVSISNS 919
Query: 977 E-------------GGETSVGNE--KDGEDCITVAVVEDSKNSVQLDSVRKSLIPFLLQT 1021
E G GNE K+ C+T+ V + + QLD +++ +IP +L T
Sbjct: 920 ETLHLKMENKSGKLGKNLGTGNECVKNQTCCVTMVVQVEINSMSQLDVIKERVIPSILAT 979
Query: 1022 AIKG 1025
+KG
Sbjct: 980 LLKG 983
Score = 211 bits (537), Expect = 1e-52
Identities = 112/218 (51%), Positives = 145/218 (66%), Gaps = 2/218 (0%)
Query: 272 LELSEIGIPCQIAEALQVSEYVNRQNRQNLLYCCELRLLEKGQINVRRNGNPVVLYKKED 331
+ L+EIGIP +A L VSE V+ N + + C L LL K + VRRNGN + + K
Sbjct: 327 INLNEIGIPMGLALNLVVSEQVSSYNFETINLKCNLHLLTKEVLLVRRNGNLIFVRKANQ 386
Query: 332 LQIGDIFYRPLVDGDKVLINRPPSIHQHSMIALTVRVLPISSVVSINPICCSPLRGDFDG 391
L+IGDI YR L DGD VL+N PPS+HQHS+IAL+ ++L S VSINP+CC P +GDFDG
Sbjct: 387 LEIGDIAYRLLQDGDLVLVNSPPSVHQHSLIALSAKLLSTQSAVSINPLCCDPFKGDFDG 446
Query: 392 DCLHGYIPQSVGARVELNELVALDRQLINGQSGGNLLSLSQDSLTAAHLLLEDGVGFNIY 451
DCLHGYIPQ + +R+EL ELV L QL+N Q G +L+SL+ DSL AAH L V
Sbjct: 447 DCLHGYIPQCLQSRIELEELVGLSGQLLNQQDGRSLVSLTHDSLAAAHQLTNADVFLEKA 506
Query: 452 QVQQLEMLCNK-ELT-SPAIFKAPSSNTPFWSGKQLFS 487
+ QQL+ML + LT P++FK+ +S P W+ LFS
Sbjct: 507 EFQQLQMLSSSISLTPMPSVFKSTNSQGPLWTDLYLFS 544
Score = 68.9 bits (167), Expect = 8e-10
Identities = 33/87 (37%), Positives = 50/87 (56%), Gaps = 10/87 (11%)
Query: 28 EKISALEINAPGQVTCSDLGLPNSSYGCTTCGSKDRKSCEG----------HFGAIKFPF 77
EK+S+ I VT + LGLPN + C TCGS+ + C+G HFG IK
Sbjct: 61 EKLSSATIIEMCDVTNAKLGLPNGAPQCATCGSRSIRDCDGKKKLTGKLLGHFGVIKLAA 120
Query: 78 TILHPYFMAEIAEILQKICPACKSIRQ 104
T+ + YF+ E+ ++L +ICP C +++Q
Sbjct: 121 TVHNSYFIEEVVQLLNQICPGCLTLKQ 147
>gb|AAX12374.1| DNA-directed RNA polymerase alpha subunit [Spinacia oleracea]
Length = 1902
Score = 224 bits (572), Expect = 9e-57
Identities = 215/725 (29%), Positives = 332/725 (45%), Gaps = 103/725 (14%)
Query: 271 YLELSEIGIPCQIAEALQVSEYVNRQNRQNLLYCCELRLLEKGQINVRRNGNPVVLYKKE 330
Y ++E+G+PC+IA+ + E VN N Q L L++K R+G ++
Sbjct: 124 YRAVNEVGVPCEIAQKMTFEERVNVHNIQYLQ-----GLVDKNLCLTFRDGLSTYSLREG 178
Query: 331 D-----LQIGDIFYRPLVDGDKVLINRPPSIHQHSMIALTVRVLPISSVVSINPICCSPL 385
L++G + +R ++DGD V INRPP+ H+HS+ AL V + VV INP+ C PL
Sbjct: 179 SKGHTFLRLGQMVHRRIMDGDIVFINRPPTTHKHSLQALRVYIHD-DHVVKINPLMCGPL 237
Query: 386 RGDFDGDCLHGYIPQSVGARVELNELVALDRQLINGQSGGNLLSLSQDSLTAAHLLLEDG 445
DFDGDC+H + PQS+ AR E+ EL ++++QL++ SG L LS DSL + + E
Sbjct: 238 AADFDGDCVHLFYPQSLSARAEVLELFSVEKQLLSSHSGNLNLQLSTDSLLSLKTMFE-- 295
Query: 446 VGF-NIYQVQQLEMLCNKELTSPAIFKAPSSNT---------PFWSGKQLFSMLLPSKFD 495
V F + QL M + L SPA++KA SSN P W+ +Q+ LPS F+
Sbjct: 296 VYFLDRASANQLAMYASSLLPSPALWKACSSNAKKKKAHSSGPRWTAQQVLQTALPSHFE 355
Query: 496 YAFPSNDVFVKDGELISCSESSGWLRDSENNVFQSLVEHFQGK-ILDVLHGAQKALCEWL 554
+ + + D E++ + + ++V SL + K LD Q L E L
Sbjct: 356 CH--GDRLLIHDSEILKLDFNRDIVASVISDVLTSLFFNKSPKDALDFFDSLQPLLMENL 413
Query: 555 SMTGFSVSLSDLYLSSDSYARKNMMEEISYGLRVAEQACDFNQLLVDHYSDFLSASPEEN 614
GFSVSL D + K+ ++ I ++ D + LL+ S F N
Sbjct: 414 FSEGFSVSLHDFFFP------KSELQNIQRNIQ------DLSPLLLQLRSSF-------N 454
Query: 615 EKFVTVDVDRLNHERQISAAQSQASVDAFRHVFRNIQSLADKHACKDNSFLAMFKAGSKG 674
E V V NH R+ ++ V F + + S+ D S
Sbjct: 455 E---LVQVQFENHIREF-----KSPVGNFILISSALGSMIDSR--------------SDS 492
Query: 675 NLLKLVQHSMCLGLQHSLVRLSYRIPRELSCAGWNSQKGLHSMEMSSDTLEPKQSYIAHA 734
+ K+VQ LGLQ S R Y A QK + + P + +
Sbjct: 493 AIDKIVQQIGFLGLQLSDRRKFYSRGLVEDVASLFHQKYPFA------DVYPSEEF---G 543
Query: 735 VVESSFLTGLNPLECFVHSVTNRDSSFSDNADL--PGTLTRRLMFFMRDMYDAYDGTVRN 792
V F GL+P E VHS+ R+ + L PGTL + LM +RD+ YDGTVRN
Sbjct: 544 FVSRCFFHGLDPYEEIVHSIATREVIVRSSKGLAEPGTLFKNLMAVLRDVVICYDGTVRN 603
Query: 793 LYGNQLIQFSYDAEEDSSCDSYFREDIIGGEPVGALSACAVSEAAYSALSQPISLLEASP 852
+ N +IQF Y S + + G+PVG L+A A+S AY A +L++SP
Sbjct: 604 ISSNSVIQFEYGVGGMQSQNLF-----PAGDPVGVLAATAMSNPAYKA------VLDSSP 652
Query: 853 LLN-----LKNVLECGS--RKKGGDQTVSLFLSEKIGKQRNGFEYAALEVKNYLERYMFS 905
N +K +L C + R D+ V L+L++ ++ E A+ VKN+L++
Sbjct: 653 NSNSSWDMMKEILFCRANFRNDINDRRVILYLNDCCCGRKYCQENASCLVKNHLKKVSLR 712
Query: 906 NIVSTVMIIF-----TPQHCSQVKYSPWVCHFHLDKENVTRRKLEVHSIIDSLYQQYDSF 960
+ + I + P+ C + V H HL+ + + +H I+ +Q +
Sbjct: 713 DAAIELAIEYKRPKLEPESCE--IDAGLVGHIHLNSGLLKASGIGMHDILQKCEEQVNLL 770
Query: 961 RRESK 965
R++ K
Sbjct: 771 RKKKK 775
>gb|AAS64314.1| DNA-dependent RNA polymerase II largest subunit [Amanita
phalloides]
Length = 1007
Score = 162 bits (409), Expect = 7e-38
Identities = 168/561 (29%), Positives = 255/561 (44%), Gaps = 81/561 (14%)
Query: 272 LELSEIGIPCQIAEALQVSEYVNRQNRQNLLYCCEL-----RLLEKGQINVRRNGNPVVL 326
LEL E+G+P IA L Y R N+ Y EL + VR G + L
Sbjct: 288 LELDEVGVPRSIAMNLT---YPERVTPYNIGYLQELVRNGPTAYPGARYVVRDTGERIDL 344
Query: 327 -YKKE---DLQIGDIFYRPLVDGDKVLINRPPSIHQHSMIALTVRVLPISSVVSINPICC 382
Y K LQ G I R L DGD VL NR PS+H+ SM++ V+++P S+ +N
Sbjct: 345 RYNKRADAHLQYGWIVERHLKDGDFVLFNRQPSLHKMSMMSHRVKLMPYSTF-RLNLSVT 403
Query: 383 SPLRGDFDGDCLHGYIPQSVGARVELNELVALDRQLINGQSGGNLLSLSQDSLTAAHLLL 442
P DFDGD ++ +IPQS R EL+++ + RQ+I+ Q+ ++ + QD+L L
Sbjct: 404 PPYNADFDGDEMNMHIPQSEETRAELSQIAWVPRQIISPQANKPVMGIVQDTLCGIRKLT 463
Query: 443 EDGVGFNIYQVQQLEMLC---NKELTSPAIFKAPSSNTPFWSGKQLFSMLLPSKFD-YAF 498
+ QVQ + + + + PAI K P WSGKQ+ SM +P + +
Sbjct: 464 LRDTFLDWNQVQNILLWVPDWDGSVPIPAILKP----KPLWSGKQILSMTIPRGINIHRS 519
Query: 499 P----SNDVF-----VKDGELISCSESSGWLRDSENNVFQSLV-EHFQGKILDVLHGAQK 548
P SN VF +++GE+I + S+ + + E +L G Q
Sbjct: 520 PDPKSSNPVFDDGMMIENGEIIFGIVEKKTVGASQGGLVHVVFREKGPEATRMLLTGIQM 579
Query: 549 ALCEWLSMTGFSVSLSD--LYLSSDSYARKNMMEEISYGLRVAEQACDFNQLLVDHYSDF 606
+ WL GFS+ + D + L + +Y RK++ + S + +L+ D D
Sbjct: 580 VVNYWLFHNGFSIGIGDTIVDLPTMAYIRKSIQDRKS----------NVAKLIEDAIHDH 629
Query: 607 LSASP--EENEKFVTVDVDRLNHERQISAAQSQASVDAFRHVFRNIQSLADKHACKDNSF 664
L A P E F ++ ER+++ A+ ++ A +H +DN+
Sbjct: 630 LKAKPGMTLRESFESM------AERELNLARDRSG------------KYAQEHMKEDNNV 671
Query: 665 LAMFKAGSKGNLLKLVQHSMCLGLQHSLVRLSYRIPRELSCAGWNSQKGLHSMEMSSDTL 724
M AGSKG+ + + Q S+C+G Q R RIP G+ + H + D
Sbjct: 672 KQMVVAGSKGSFINISQMSVCVGQQSVEGR---RIP-----FGFRHRSLPH---FTKDDF 720
Query: 725 EPKQSYIAHAVVESSFLTGLNPLECFVHSVTNRDSSFSDNADL--PGTLTRRLMFFMRDM 782
P A VE+S+L GL P E F H++ R+ G + RRL+ + D+
Sbjct: 721 GPD----ARGFVENSYLRGLTPQEFFFHAMAGREGLIDTAVKTAETGYIQRRLVKALEDV 776
Query: 783 YDAYDGTVRNLYGNQLIQFSY 803
YDGTVRN G+ LIQF Y
Sbjct: 777 MVCYDGTVRNSLGD-LIQFIY 796
>emb|CAC33863.1| RNA polymerase II largest subunit [Pleistophora sp. LS]
Length = 897
Score = 160 bits (404), Expect = 3e-37
Identities = 169/667 (25%), Positives = 289/667 (42%), Gaps = 93/667 (13%)
Query: 272 LELSEIGIPCQIAEALQVSEYVNRQNRQNLLYCCELRLLEKGQIN-------VRRNGNPV 324
++L E+G+P +IA + + + N N++ EL +++G +R +G +
Sbjct: 241 IDLDELGVPREIAV---IETFPEKVNSYNIIRLSEL--VKRGPAQYPGANYVIRGDGMKI 295
Query: 325 VLY--KKEDLQIGDIFYRPLVDGDKVLINRPPSIHQHSMIALTVRVLPISSVVSINPICC 382
L + +LQIG R +VDGD VL NR PS+H+ SM+ VRV+ S +N
Sbjct: 296 DLRFTRSVELQIGWTVERHMVDGDYVLFNRQPSLHKMSMMCHRVRVMEGKSF-RLNLSVT 354
Query: 383 SPLRGDFDGDCLHGYIPQSVGARVELNELVALDRQLINGQSGGNLLSLSQDSLTAAHLL- 441
+P DFDGD ++ ++PQS VEL L + +++ QS ++ + QD+L +++
Sbjct: 355 TPYNADFDGDEMNLHMPQSYITAVELRRLTHVPLHILSPQSNKPIMGIVQDTLVGVYIMS 414
Query: 442 -----LEDGVGFNIYQVQQLEMLCNKELTSPAIFKAPSSNTPFWSGKQLFSMLLPSKFDY 496
+E+ N+ ++ C +PAI + ++GKQLFSM+LP Y
Sbjct: 415 GDSIFIEESTTHNLMYTVDIDSKC-----TPAILRPER----IYTGKQLFSMVLPPTLIY 465
Query: 497 AFPSNDVFVKDGELISCSESSGWLRDSENNVFQSLVEHFQGKI-LDVLHGAQKALCEWLS 555
++++ + DG LI S + N++ L + K+ L + Q+ + +LS
Sbjct: 466 C--TDNIKIVDGVLIKGVVSKKVVGSVRNSLIHILYLDYGAKVALSFFNNIQRVVTAFLS 523
Query: 556 MTGFSVSLSDLYLSSDSYARKNMMEEISYGLRVAEQACDFNQLLVDHYSDFLSASP--EE 613
GFS + D D+ + N EE+ + N LL++ L P
Sbjct: 524 SYGFSCGIGDTIADFDTSMKIN--EELK------DAVDSVNGLLLEGRDRKLRRRPGLSL 575
Query: 614 NEKFVTVDVDRLNHERQISAAQSQASVDAFRHVFRNIQSLADKHACKDNSFLAMFKAGSK 673
E F + + LN R S +Q S+ + DN+ M AGSK
Sbjct: 576 RETFESSVMQILNKARDTSGTVAQKSLSS------------------DNNLRTMVLAGSK 617
Query: 674 GNLLKLVQHSMCLGLQHSLVRLSYRIPRELSCAGWNSQKGLHSMEMSSDTLEPKQSYIAH 733
G+ + + Q + C+G Q R ++C + ++ L S D L P+ A
Sbjct: 618 GSFINISQVTACVGQQTV-------EGRRIACGYYYHKRTL--PHFSRDDLSPR----AR 664
Query: 734 AVVESSFLTGLNPLECFVHSVTNRDSSFSDNADL--PGTLTRRLMFFMRDMYDAYDGTVR 791
V +S+L+GLNP E + H++ R+ G + RRL+ M ++ YDG
Sbjct: 665 GFVVNSYLSGLNPDEFYFHAMGGREGLIDTACKTAETGYMQRRLIKAMENLRVEYDG--- 721
Query: 792 NLYGNQLIQFSY-------DAEEDSSCDSYFREDIIGGEPVGALSACAVSEAAYSALSQP 844
N+ +++F Y DA C I GE + A C E Q
Sbjct: 722 NVGDGGIVRFGYGDGNDGWDANISGECRGVQYNPI--GEYIDAYIQCKSIEEEMKCERQT 779
Query: 845 I---SLLEASPLLNLKNVLECGSRKKGGDQTVSLFLSEKIGKQRNGFEYAALEVKNYLER 901
+ S ++ + +N+K VL R +F S K +N +Y +++ + R
Sbjct: 780 LSASSTIKCTMPINIKRVLSTAMRFDTVPANYRIFFSSKRALIKNMLKYLDMDI--IIHR 837
Query: 902 YMFSNIV 908
+ +NI+
Sbjct: 838 VLLNNIL 844
>gb|AAF36438.2| RNA polymerase II largest subunit [Leishmania donovani]
Length = 1665
Score = 159 bits (402), Expect = 5e-37
Identities = 141/551 (25%), Positives = 250/551 (44%), Gaps = 65/551 (11%)
Query: 272 LELSEIGIPCQIAEALQVSEYVNRQNRQNLLYCCELRLLEKGQINVRRNGNPVVLYKKED 331
+++ E+G+P +A L E VN N++ L + +R NGN L +D
Sbjct: 343 IDVDEVGVPFSVAMTLTFPERVNVINKKRLTEFVQRTTYPSANYIIRPNGNVTKLALVKD 402
Query: 332 -----LQIGDIFYRPLVDGDKVLINRPPSIHQHSMIALTVRVLPISSVVSINPICCSPLR 386
L +GD+ R ++DGD VL NR P++H+ SM+ VRVL ++ +N C +P
Sbjct: 403 RNAVHLDVGDVVERHVIDGDVVLFNRQPTLHRMSMMGHRVRVLNYNTF-RLNLSCTTPYN 461
Query: 387 GDFDGDCLHGYIPQSVGARVELNELVALDRQLINGQSGGNLLSLSQDSLTAAHLLLEDGV 446
DFDGD ++ ++PQS+ + EL E++ + + ++ + + QDSL ++ L +
Sbjct: 462 ADFDGDEMNLHVPQSLLTKAELIEMMMVPKNFVSPNKSAPCMGIVQDSLLGSYRLTDKDT 521
Query: 447 GFNIYQVQQLEMLCNK-ELTSPAIFKAPSSNTPFWSGKQLFSMLLP------SKFDYA-F 498
+ Y +Q + + + EL PAI K P W+GKQ+FS++LP S +D F
Sbjct: 522 FVDKYFIQSVALWLDLWELPIPAILKP----RPLWTGKQIFSLILPEVNHPASPYDKPPF 577
Query: 499 PSND--VFVKDGELISCSESSGWLRDSENNVFQSLV-EHFQGKILDVLHGAQKALCEWLS 555
P ND + ++ G+L+ + + G + + ++ + E ++ ++G Q+ +
Sbjct: 578 PHNDKKIMIQRGQLLVGAITKGVVGAAPGSLIHVIFNERGSDEVAKFINGVQRITTYFNY 637
Query: 556 MTGFSVSLSDLYLSSDSYAR-KNMMEEISYGLRVAEQACDFNQLLVDHYSDFLSASPEEN 614
FSV + D + + N++ + + A + QL L +
Sbjct: 638 CFAFSVGVQDTVADATTLKEMNNVLHKTRQSVEKIGAAANNGQLTRKAGMSLLQS----- 692
Query: 615 EKFVTVDVDRLNHERQISAAQSQASVDAFRHVFRNIQSLADKHACKDNSFLAMFKAGSKG 674
E +++A ++ +A + N++ + NSF M +AGSKG
Sbjct: 693 ------------FEADVNSALNKCREEAAKKALSNVR--------RTNSFKVMIEAGSKG 732
Query: 675 NLLKLVQHSMCLGLQHSLVRLSYRIPRELSCAGWNSQKGLHSMEMSSDTLEPKQSYIAHA 734
+ L + Q ++ +G Q+ RIP G+ + H M D E +
Sbjct: 733 SDLNICQIAVFVGQQNVA---GSRIP-----FGFRRRTLPHFM--LDDYGETSRGMATRG 782
Query: 735 VVESSFLTGLNPLECFVHSVTNRDSSFSDNADLPGT--LTRRLMFFMRDMYDAYDGTVRN 792
VE GL P E + H++ R+ T L R+L+ + D++ +YDGTVRN
Sbjct: 783 YVE-----GLQPHEFYFHTMAGREGLIDTAVKTSDTGYLQRKLVKALEDVHASYDGTVRN 837
Query: 793 LYGNQLIQFSY 803
+LIQ +Y
Sbjct: 838 A-NQELIQLAY 847
Score = 36.2 bits (82), Expect = 5.8
Identities = 22/80 (27%), Positives = 35/80 (43%), Gaps = 3/80 (3%)
Query: 25 CLQEKISALEINAPGQVTCSDL--GLPNSSYGCTTCGSKDRKSCEGHFGAIKFPFTILHP 82
C+ E + E P + +DL G + Y C TCG K C GHFG ++ I +
Sbjct: 36 CIIEHAKSYEHGQPVRGGINDLRMGTTDFEYSCETCGLK-HPECPGHFGYVELAEPIFNI 94
Query: 83 YFMAEIAEILQKICPACKSI 102
+ L+ +C C ++
Sbjct: 95 NVFDVVLIALKCVCKYCGAL 114
>gb|AAK97604.2| RNA polymerase II largest subunit [Trypanosoma cruzi]
Length = 1731
Score = 157 bits (397), Expect = 2e-36
Identities = 142/553 (25%), Positives = 246/553 (43%), Gaps = 69/553 (12%)
Query: 272 LELSEIGIPCQIAEALQVSEYVNRQNRQNLLYCCELRLLEKGQINVRRNGNPVVLYKKED 331
+++ E+G+P IA L E V+ N++ L + NG L + D
Sbjct: 350 IDVDEVGVPFSIAMTLTFPERVSAVNKKRLTEFVRRPVYPSANYIHHPNGTTTKLALRRD 409
Query: 332 -----LQIGDIFYRPLVDGDKVLINRPPSIHQHSMIALTVRVLPISSVVSINPICCSPLR 386
L IGD+ R +++GD VL NR P++H+ SM+ VRVL ++ +N C +P
Sbjct: 410 RSKVTLNIGDVVERHVINGDVVLFNRQPTLHRMSMMGHRVRVLNYNTF-RLNLSCTTPYN 468
Query: 387 GDFDGDCLHGYIPQSVGARVELNELVALDRQLINGQSGGNLLSLSQDSLTAAHLLLEDGV 446
DFDGD ++ ++PQS+ + EL E++ + + ++ + + QDSL ++ L +
Sbjct: 469 ADFDGDEMNLHVPQSLLTKAELIEMMMVPKNFVSPNKSAPCMGIVQDSLLGSYRLTDKDT 528
Query: 447 GFNIYQVQQLEMLCNK-ELTSPAIFKAPSSNTPFWSGKQLFSMLLPSKFDYA-------F 498
+ Y VQ + + + +L PA+ K P W+GKQ+FS++LP A F
Sbjct: 529 FLDKYFVQSVALWLDLWQLPVPAVLKP----RPLWTGKQVFSLILPEVNHPATPQERPPF 584
Query: 499 PSND--VFVKDGELISCSESSGWLRDSENNVFQSLV-EHFQGKILDVLHGAQKALCEWLS 555
P ND + ++ G+L+ + G + + ++ + E ++ ++G Q+ +L
Sbjct: 585 PHNDSSIMIRRGQLLCGPITKGIVGAAPGSLIHVIFNERGSDEVARFINGVQRITTFFLI 644
Query: 556 MTGFSVSLSDLYLSSDSYARKNMMEEISYGLRVAEQACDFNQLLVDHYSDFLSASPEENE 615
GFSV + D +D+ + N++LV + N
Sbjct: 645 NFGFSVGVQDTVADADTLRQ-------------------MNEVLVKTRENVEKIGAAANN 685
Query: 616 KFVTVDVDRL---NHERQISAAQSQASVDAFRHVFRNIQSLADKHACKDNSFLAMFKAGS 672
+ + + E +++A ++ +A + N++ + NSF M +AGS
Sbjct: 686 RTLNRKAGMTLLQSFEADVNSALNKCREEAAKKALSNVR--------RTNSFKVMIEAGS 737
Query: 673 KGNLLKLVQHSMCLGLQHSLVRLSYRIPRELSCAGWNSQKGLHSMEMSSDTLEPKQSYIA 732
KG L + Q ++ +G Q+ RIP G+ + H M D E +
Sbjct: 738 KGTDLNICQIAVFVGQQNVA---GSRIP-----FGFRRRTLPHFM--LDDYGETSRGMAN 787
Query: 733 HAVVESSFLTGLNPLECFVHSVTNRDSSFSDNADLPGT--LTRRLMFFMRDMYDAYDGTV 790
VE GL P E F H++ R+ T L R+L+ + D++ AYDGTV
Sbjct: 788 RGYVE-----GLKPHEFFFHTMAGREGLIDTAVKTSDTGYLQRKLIKALEDVHAAYDGTV 842
Query: 791 RNLYGNQLIQFSY 803
RN +LIQF Y
Sbjct: 843 RNA-NQELIQFMY 854
Score = 36.6 bits (83), Expect = 4.4
Identities = 21/81 (25%), Positives = 37/81 (44%), Gaps = 3/81 (3%)
Query: 24 LCLQEKISALEINAPGQVTCSDL--GLPNSSYGCTTCGSKDRKSCEGHFGAIKFPFTILH 81
+CL E + E P + +DL G + + C TC K C GHFG I + +
Sbjct: 35 VCLVEHAKSYERGQPVRGGINDLRMGTTDFEFACETCHRK-HPECPGHFGYIDLAEPVFN 93
Query: 82 PYFMAEIAEILQKICPACKSI 102
+ ++L+ +C +C ++
Sbjct: 94 IGVFDIVLQVLKCVCKSCGAL 114
>gb|AAW51135.1| RNA polymerase II largest subunit [Calostoma cinnabarinum]
Length = 994
Score = 156 bits (395), Expect = 3e-36
Identities = 170/565 (30%), Positives = 256/565 (45%), Gaps = 89/565 (15%)
Query: 272 LELSEIGIPCQIAEALQVSEYVNRQNRQNLLYCCELRLLEKG-------QINVRRNGNPV 324
LEL E+G+P +A L E V N L L+ G + VR G +
Sbjct: 280 LELDEVGVPISVAMNLTYPERVTPFNIHKLQ-----ELVRNGPNEYPGARYVVRDTGERI 334
Query: 325 VL-YKKED---LQIGDIFYRPLVDGDKVLINRPPSIHQHSMIALTVRVLPISSVVSINPI 380
L Y K LQ G I R L DGD VL NR PS+H+ SM++ V+++P S+ +N
Sbjct: 335 DLRYNKRTDAFLQHGWIVERHLRDGDYVLFNRQPSLHKMSMMSHRVKLMPYSTF-RLNLS 393
Query: 381 CCSPLRGDFDGDCLHGYIPQSVGARVELNELVALDRQLINGQSGGNLLSLSQDSLTAAHL 440
P DFDGD ++ +IPQS R EL+++ + Q+I+ Q+ ++ + QD+L
Sbjct: 394 VTPPYNADFDGDEMNMHIPQSEETRAELSQIAWVPLQIISPQANKPVMGIVQDTLCGIRK 453
Query: 441 LLEDGVGFNIYQVQQLEMLC---NKELTSPAIFKAPSSNTPFWSGKQLFSMLLPSKFD-Y 496
+ QVQ + + + + +PAI K P WSGKQ+ SM++P + +
Sbjct: 454 FTLRDTFLDWNQVQNILLWVPDWDGHVPTPAIIKP----KPLWSGKQILSMVIPRGINIH 509
Query: 497 AFP----SNDVFVKDGELISCSESSGWLRDSEN-NVFQSLVEH--FQGKILD----VLHG 545
P SN VF DG LI E + D + Q + H F+ K D V G
Sbjct: 510 XAPDPKSSNPVF-DDGMLIDNGEILFGIMDKKTVGATQGGLIHVVFREKGPDATRQVFTG 568
Query: 546 AQKALCEWLSMTGFSVSLSDLYLSSDSYARKNMMEEISYGLRVAEQACDFNQLLVDHYSD 605
Q + WL GFS+ + D+ A +M I+ ++AE+ ++++ D Y D
Sbjct: 569 IQIVVNYWLYHNGFSIXI------GDTIAGPKVMSFITD--KIAEKKQKVSEIIDDAYHD 620
Query: 606 FLSASP-----EENEKFVTVDVDRLNHERQISAAQSQASVDAFRHVFRNIQSLADKHACK 660
L A P E E V ER+++ A+ ++ A K+ +
Sbjct: 621 RLRAMPGMTIRESFENMV---------ERELNRARDESG------------QYAQKNLKE 659
Query: 661 DNSFLAMFKAGSKGNLLKLVQHSMCLGLQHSLVRLSYRIPRELSCAGWNSQKGLHSMEMS 720
DN+ M AGSKG+ + + Q S+C+G Q + RIP G+ + H +
Sbjct: 660 DNNVKQMVTAGSKGSYINISQMSVCVGQQSVEGK---RIP-----FGFRHRTLPH---FN 708
Query: 721 SDTLEPKQSYIAHAVVESSFLTGLNPLECFVHSVTNRDSSFSDNADL--PGTLTRRLMFF 778
D P+ A VE+S+L GL P E F H++ + G + RRL+
Sbjct: 709 KDDFSPE----ARGFVENSYLRGLTPQEFFFHAMGGXEGLIDTAVKTAETGYIQRRLVKA 764
Query: 779 MRDMYDAYDGTVRNLYGNQLIQFSY 803
+ D+ YDGTVRN G+ LIQF Y
Sbjct: 765 LEDVMVHYDGTVRNSLGD-LIQFIY 788
>gb|AAN17722.1| RNA polymerase II largest subunit [Trypanosoma cruzi]
Length = 1731
Score = 156 bits (394), Expect = 4e-36
Identities = 142/553 (25%), Positives = 246/553 (43%), Gaps = 69/553 (12%)
Query: 272 LELSEIGIPCQIAEALQVSEYVNRQNRQNLLYCCELRLLEKGQINVRRNGNPVVLYKKED 331
+++ E+G+P IA L E V+ N++ L + NG L + D
Sbjct: 350 IDVDEVGVPFSIAMTLTFPERVSAVNKKRLTEFVRRPVYPSAFYIHHPNGTSTKLALRRD 409
Query: 332 -----LQIGDIFYRPLVDGDKVLINRPPSIHQHSMIALTVRVLPISSVVSINPICCSPLR 386
L IGD+ R +++GD VL NR P++H+ SM+ VRVL ++ +N C +P
Sbjct: 410 RSKVTLNIGDVVERHVINGDVVLFNRQPTLHRMSMMGHRVRVLNYNTF-RLNLSCTTPYN 468
Query: 387 GDFDGDCLHGYIPQSVGARVELNELVALDRQLINGQSGGNLLSLSQDSLTAAHLLLEDGV 446
DFDGD ++ ++PQS+ + EL E++ + + ++ + + QDSL ++ L +
Sbjct: 469 ADFDGDEMNLHVPQSLLTKAELIEMMMVPKNFVSPNKSAPCMGIVQDSLLGSYRLTDKDT 528
Query: 447 GFNIYQVQQLEMLCNK-ELTSPAIFKAPSSNTPFWSGKQLFSMLLPSKFDYA-------F 498
+ Y VQ + + + +L PA+ K P W+GKQ+FS++LP A F
Sbjct: 529 FLDKYFVQSVALWLDLWQLPVPAVLKP----RPLWTGKQVFSLILPEVNHPATPQERPPF 584
Query: 499 PSND--VFVKDGELISCSESSGWLRDSENNVFQSLV-EHFQGKILDVLHGAQKALCEWLS 555
P ND + ++ G+L+ + G + + ++ + E ++ ++G Q+ +L
Sbjct: 585 PHNDSSIMIRRGQLLCGPITKGIVGAAPGSLIHVIFNERGSDEVARFINGVQRITTFFLI 644
Query: 556 MTGFSVSLSDLYLSSDSYARKNMMEEISYGLRVAEQACDFNQLLVDHYSDFLSASPEENE 615
GFSV + D +D+ + N++LV + N
Sbjct: 645 NFGFSVGVQDTVADADTLRQ-------------------MNEVLVKTRENVEKIGAAANN 685
Query: 616 KFVTVDVDRL---NHERQISAAQSQASVDAFRHVFRNIQSLADKHACKDNSFLAMFKAGS 672
+ + + E +++A ++ +A + N++ + NSF M +AGS
Sbjct: 686 RTLNRKAGMTLLQSFEADVNSALNKCREEAAKKALSNVR--------RTNSFKVMIEAGS 737
Query: 673 KGNLLKLVQHSMCLGLQHSLVRLSYRIPRELSCAGWNSQKGLHSMEMSSDTLEPKQSYIA 732
KG L + Q ++ +G Q+ RIP G+ + H M D E +
Sbjct: 738 KGTDLNICQIAVFVGQQNVA---GSRIP-----FGFRRRTLPHFM--LDDYGETSRGMAN 787
Query: 733 HAVVESSFLTGLNPLECFVHSVTNRDSSFSDNADLPGT--LTRRLMFFMRDMYDAYDGTV 790
VE GL P E F H++ R+ T L R+L+ + D++ AYDGTV
Sbjct: 788 RGYVE-----GLKPHEFFFHTMAGREGLIDTAVKTSDTGYLQRKLIKALEDVHAAYDGTV 842
Query: 791 RNLYGNQLIQFSY 803
RN +LIQF Y
Sbjct: 843 RNA-NQELIQFMY 854
Score = 36.6 bits (83), Expect = 4.4
Identities = 21/81 (25%), Positives = 37/81 (44%), Gaps = 3/81 (3%)
Query: 24 LCLQEKISALEINAPGQVTCSDL--GLPNSSYGCTTCGSKDRKSCEGHFGAIKFPFTILH 81
+CL E + E P + +DL G + + C TC K C GHFG I + +
Sbjct: 35 VCLVEHAKSYERGQPVRGGINDLRMGTTDFEFACETCHRK-HPECPGHFGYIDLAEPVFN 93
Query: 82 PYFMAEIAEILQKICPACKSI 102
+ ++L+ +C +C ++
Sbjct: 94 IGVFDIVLQVLKCVCKSCGAL 114
>gb|AAM45151.1| RNA polymerase II largest subunit [Naegleria gruberi]
Length = 1590
Score = 155 bits (393), Expect = 5e-36
Identities = 164/578 (28%), Positives = 259/578 (44%), Gaps = 102/578 (17%)
Query: 272 LELSEIGIPCQIAEALQVSEYVNRQNRQNLLYCCELRLLEKGQIN-------VRRNGNPV 324
+++ ++G+P +A + V E V N + L L+ G + +R +G +
Sbjct: 290 IDIDQVGVPRTVASNMTVPEIVTPFNFERLN-----ELVTNGPLTYPGAKYVIREDGTRI 344
Query: 325 VLY----KKED---LQIGDIFYRPLVDGDKVLINRPPSIHQHSMIALTVRVLPISSVVSI 377
L K D L+ G R L DGD +L NR PS+H+ SM+ ++V+P S+ +
Sbjct: 345 DLRFASGKANDQIQLEYGYKVERHLQDGDVILFNRQPSLHKMSMMGHRIKVMPYSTF-RM 403
Query: 378 NPICCSPLRGDFDGDCLHGYIPQSVGARVELNELVALDRQLINGQSGGNLLSLSQDSLTA 437
N +P DFDGD ++ ++PQS+ + EL EL + R +I QS +++L QD+L A
Sbjct: 404 NLSVTTPYNADFDGDEMNLHVPQSLQTKAELLELTMVPRNIITPQSNRPVIALVQDTLLA 463
Query: 438 AHLLLEDGVGFNIYQVQQLEMLC-------NKELTSPAIFKAPSSNTPFWSGKQLFSMLL 490
A L +++ + L M C + +L PAI K P W+GKQLF+ LL
Sbjct: 464 ASKLTRR----DVFIAKDLMMNCLMHLIDFDGKLPVPAILKP----KPLWTGKQLFTFLL 515
Query: 491 P------------------SKFDYAFPSND--VFVKDGELISCSESSGWLRDSENNVFQS 530
P D+ P D V + GEL+S L S ++
Sbjct: 516 PKVNLENTSSTHEDLTDKKDHLDHDIPEFDTKVLIDRGELVSGVLDKKSLGSSHGSLIHI 575
Query: 531 LVEH---FQGKILDVLHGAQKALCEWLSMTGFSVSLSDLYLSSDSYARKNMMEEISYGLR 587
+V +GK L Q+ + WL GFS+ + D+ A K ME+I +R
Sbjct: 576 IVNEKGVNEGK--KFLGQCQRVINHWLINRGFSIGI------GDTIADKATMEQIEETIR 627
Query: 588 VAEQACDFNQLLVDHYSDFLSASPEENEKFVTVDVDRLNHERQISAAQSQASVDAFRHVF 647
AE+ D ++ D L A E T+ + + E Q++ ++A DA
Sbjct: 628 KAEK--DVKLIVKDAQEGKLRA-----EAGRTI---QQSFENQVNKVLNKAREDA----- 672
Query: 648 RNIQSLADKHACKDNSFLAMFKAGSKGNLLKLVQHSMCLGLQHSLVRLSYRIPRELSCAG 707
+ A K DN+ +M AGSKG+ + + Q C+G Q+ + RIP G
Sbjct: 673 ---GNKAKKSLKDDNNIKSMVTAGSKGSYINISQIIACVGQQNVEGK---RIP-----YG 721
Query: 708 WNSQKGLHSMEMSSDTLEPKQSYIAHAVVESSFLTGLNPLECFVHSVTNRDSSFSD--NA 765
+ ++ H + D P+ + V +S+L GL P E F H++ R+
Sbjct: 722 FRNRTLPH---FAQDDHGPE----SRGFVANSYLRGLTPQEFFFHTMGGREGLIDTAVKT 774
Query: 766 DLPGTLTRRLMFFMRDMYDAYDGTVRNLYGNQLIQFSY 803
G + RRL+ M D+ YDGTVR+ GN ++QF Y
Sbjct: 775 SETGYIQRRLIKAMEDIMVKYDGTVRDAQGN-VVQFLY 811
>gb|AAS52006.1| ADR086Cp [Ashbya gossypii ATCC 10895] gi|45187959|ref|NP_984182.1|
ADR086Cp [Eremothecium gossypii]
gi|51701979|sp|Q75A34|RPB1_ASHGO DNA-directed RNA
polymerase II largest subunit (RNA polymerase II subunit
1)
Length = 1745
Score = 155 bits (392), Expect = 7e-36
Identities = 159/564 (28%), Positives = 250/564 (44%), Gaps = 86/564 (15%)
Query: 272 LELSEIGIPCQIAEALQVSEYVNRQNRQNLLYCCELRLLEKG-------QINVRRNGNPV 324
L+L ++G+P IA+ L E V N L +L+ G + +R NG+ +
Sbjct: 359 LDLDQVGVPKSIAKTLTYPEVVTPYNIDRLT-----QLVRNGPNEHPGAKYVIRDNGDRI 413
Query: 325 VL-YKKE----DLQIGDIFYRPLVDGDKVLINRPPSIHQHSMIALTVRVLPISSVVSINP 379
L Y K LQ G R ++D D VL NR PS+H+ SM+A V+V+P S+ +N
Sbjct: 414 DLRYSKRAGDIQLQYGWKVERHIMDDDPVLFNRQPSLHKMSMMAHRVKVMPYSTF-RLNL 472
Query: 380 ICCSPLRGDFDGDCLHGYIPQSVGARVELNELVALDRQLINGQSGGNLLSLSQDSLTAAH 439
SP DFDGD ++ ++PQS R EL++L A+ Q+++ QS + + QD+L
Sbjct: 473 SVTSPYNADFDGDEMNLHVPQSEETRAELSQLCAVPLQIVSPQSNKPCMGIVQDTLCGIR 532
Query: 440 LLLEDGVGFNIYQVQQLEMLC-----NKELTSPAIFKAPSSNTPFWSGKQLFSMLLPS-- 492
+ + QV L ML + + +P I K P WSGKQL SM +PS
Sbjct: 533 KMTLRDTFIELDQV--LNMLYWIPDWDGVIPTPTILKPK----PLWSGKQLLSMAIPSGI 586
Query: 493 ---KFD----YAFPS-NDVFVKDGELISCSESSGWLRDSENNVFQSLVEHFQGKILDVLH 544
+FD Y P N + + DG++I + S + + ++ L
Sbjct: 587 HLQRFDEGTTYLSPKDNGMLIIDGQIIFGVVDKKTVGSSSGGLIHVVTREKGPEVCAKLF 646
Query: 545 G-AQKALCEWLSMTGFSVSLSDLYLSSDSYARKNMMEEISYGLRVAEQACDFNQLLVDHY 603
G QK + WL GFS+ + D + A + M EI+ + +A++ + ++ +
Sbjct: 647 GNIQKVVNYWLLHNGFSIGIGD------TIADEKTMREITDAIALAKKKVE--EVTKEAQ 698
Query: 604 SDFLSASPEEN--EKFVTVDVDRLNHERQISAAQSQASVDAFRHVFRNIQSLADKHACKD 661
++ L+A E F V LN R + ++ N++ L
Sbjct: 699 ANLLTAKHGMTLRESFEDNVVRYLNEARDKAGRSAEV----------NLKDL-------- 740
Query: 662 NSFLAMFKAGSKGNLLKLVQHSMCLGLQHSLVRLSYRIPRELSCAGWNSQKGLHSMEMSS 721
N+ M AGSKG+ + + Q S C+G Q + + G+ + H S
Sbjct: 741 NNVKQMVSAGSKGSFINIAQMSACVGQQS--------VEGKRIAFGFADRTLPH---FSK 789
Query: 722 DTLEPKQSYIAHAVVESSFLTGLNPLECFVHSVTNRDSSFSDNADLP--GTLTRRLMFFM 779
D P+ VE+S+L GL P E F H++ R+ G + RRL+ +
Sbjct: 790 DDYSPESK----GFVENSYLRGLTPQEFFFHAMGGREGLIDTAVKTAETGYIQRRLVKAL 845
Query: 780 RDMYDAYDGTVRNLYGNQLIQFSY 803
D+ YDGT RN GN +IQF Y
Sbjct: 846 EDIMVHYDGTTRNSLGN-IIQFVY 868
Score = 40.4 bits (93), Expect = 0.31
Identities = 21/73 (28%), Positives = 38/73 (51%), Gaps = 10/73 (13%)
Query: 46 LGLPNSSYGCTTCGSKDRKSCEGHFGAIKFPFTILHPYFMAEIAEILQKICPAC------ 99
LG + ++ C TCG + C GHFG I+ + H F+++I ++ + +C C
Sbjct: 58 LGSIDRNFKCQTCG-EGMNDCPGHFGHIELAKPVFHIGFISKIKKVCECVCMHCGKLLLD 116
Query: 100 ---KSIRQEIRVK 109
+ +RQ I++K
Sbjct: 117 EYNELMRQAIKIK 129
>gb|AAK15346.1| RNA polymerase II largest subunit [Leptomonas seymouri]
Length = 1657
Score = 155 bits (392), Expect = 7e-36
Identities = 143/549 (26%), Positives = 250/549 (45%), Gaps = 62/549 (11%)
Query: 272 LELSEIGIPCQIAEALQVSEYVNRQNRQNLLYCCELRLLEKGQINVRRNGNPVVLYKKED 331
+++ E+G+P IA L E VN N++ L + +R NGN L +D
Sbjct: 343 IDVDEVGVPFSIAMTLTFPERVNVINKKRLTEFVQRSTYPSANYIMRPNGNVTKLALVKD 402
Query: 332 -----LQIGDIFYRPLVDGDKVLINRPPSIHQHSMIALTVRVLPISSVVSINPICCSPLR 386
L +GD+ R ++DGD VL NR P++H+ SM+ VRVL ++ +N C +P
Sbjct: 403 RSAVHLDVGDVVERHVIDGDVVLFNRQPTLHRMSMMGHRVRVLNYNTF-RLNLSCTTPYN 461
Query: 387 GDFDGDCLHGYIPQSVGARVELNELVALDRQLINGQSGGNLLSLSQDSLTAAHLLLEDGV 446
DFDGD ++ ++PQS+ + EL E++ + + ++ + + QDSL ++ L +
Sbjct: 462 ADFDGDEMNLHVPQSLLTKAELIEMMMVPKNFVSPNKSAPCMGIVQDSLLGSYRLTDKDT 521
Query: 447 GFNIYQVQQLEMLCNK-ELTSPAIFKAPSSNTPFWSGKQLFSMLLPSKFDYA-------F 498
+ Y +Q + + + EL PAI K P W+GKQ+FS++LP A F
Sbjct: 522 FVDKYFIQSVALWLDLWELPIPAILKP----RPLWTGKQIFSLILPEVNHPASPYGKPPF 577
Query: 499 PSNDV-FVKDGELISCSESSGWLRDSENNVFQSLV-EHFQGKILDVLHGAQKALCEWLSM 556
P ND ++ G L+ + + G + + ++ + E ++ ++G Q+ +
Sbjct: 578 PHNDKKIIQRGLLLVGAITKGVVGAAPGSLIHVIFNERGSDEVAKFINGVQRITTYFNYC 637
Query: 557 TGFSVSLSDLYLSSDSYARKNMMEEISYGLRVAEQACDFNQLLVDHYSDFLSASPEENEK 616
FSV + D + A + ++E++ L Q+ + ++ A +
Sbjct: 638 FAFSVGVQD------TVADASTLKEMNNVLHKTRQSVEKIGAAANNGKLTRKAGMSLLQS 691
Query: 617 FVTVDVDRLNHERQISAAQSQASVDAFRHVFRNIQSLADKHACKDNSFLAMFKAGSKGNL 676
F E +++A ++ +A + N++ + NSF M +AGSKG+
Sbjct: 692 F----------EADVNSALNKCREEAAKKALSNVR--------RTNSFKVMIEAGSKGSD 733
Query: 677 LKLVQHSMCLGLQHSLVRLSYRIPRELSCAGWNSQKGLHSMEMSSDTLEPKQSYIAHAVV 736
L + Q ++ +G Q+ RIP G+ + H M D E + V
Sbjct: 734 LNICQIAVFVGQQNVA---GSRIP-----FGFRRRTLPHFM--LDDYGETSRGMATRGYV 783
Query: 737 ESSFLTGLNPLECFVHSVTNRDSSFSDNADLPGT--LTRRLMFFMRDMYDAYDGTVRNLY 794
E GL P E + H++ R+ T L R+L+ + D++ AYDGTVRN
Sbjct: 784 E-----GLQPHEFYFHTMAGREGLIDTAVKTSDTGYLQRKLIKALEDVHAAYDGTVRNA- 837
Query: 795 GNQLIQFSY 803
+LIQ +Y
Sbjct: 838 NQELIQLAY 846
>gb|AAK00312.1| DNA-dependent RNA polymerase II largest subunit RPB1 [Monoblepharis
macrandra]
Length = 1603
Score = 154 bits (390), Expect = 1e-35
Identities = 156/563 (27%), Positives = 254/563 (44%), Gaps = 80/563 (14%)
Query: 272 LELSEIGIPCQIAEALQVSEYVNRQNRQNLLYCCELRLLEKGQIN--VRRNGNPVVLYKK 329
+ + E+G+P I L E VN NR +L E N +R NG+ V L
Sbjct: 295 ISIDEVGVPRSICRNLTFPEIVNDYNRDHLQKLVANGTNEYPGANRVIRANGDIVSLKHT 354
Query: 330 ED-----LQIGDIFYRPLVDGDKVLINRPPSIHQHSMIALTVRVLPISSVVSINPICCSP 384
L IGD R LVDGD ++ NR PS+H+ SM+ VRV+P S+ +N SP
Sbjct: 355 AGSGETLLNIGDRVERHLVDGDYIIFNRQPSLHKMSMMGHKVRVMPFST-FRLNLSVTSP 413
Query: 385 LRGDFDGDCLHGYIPQSVGARVELNELVALDRQLINGQSGGNLLSLSQDSLTAA------ 438
DFDGD ++ + PQS R E+ E++ + RQ+I+ + ++ + QD+L
Sbjct: 414 YNADFDGDEMNLHAPQSYETRAEIMEIMRVPRQIISPKHNQPVMGIVQDTLCGIRKFTIR 473
Query: 439 -HLLLEDGVGFNIYQVQQLEMLCNKELTSPAIFKAPSSNTPFWSGKQLFSMLLP------ 491
+ L D V + V+ + + + PAI K P W+GKQ+ S+ +P
Sbjct: 474 DNFLSRDMVMNILMWVEDWDGV----IPLPAIVKP----VPLWTGKQMMSLAIPDINLVG 525
Query: 492 --------SKFDYAFPSNDVFVKDGELISCSESSGWLRDSENNVFQSLV-EHFQGKILDV 542
K D + V ++ G ++S + + S V +++ EH
Sbjct: 526 FSATHPDDEKGDMSVGDTKVIIEGGTILSGTMCKKTVGSSAGGVIHTIMNEHGPDAAKKF 585
Query: 543 LHGAQKALCEWLSMTGFSVSLSDLYLSSDSYARKNMMEEISYGLRVAEQACDFNQLLVDH 602
+G QK + WL GFSV + D+ A M+ I+ ++ A+ D +++ +
Sbjct: 586 FNGTQKIVNYWLLHNGFSVGI------GDTIADGVTMQSITDTIKKAK--ADVAEIIKNA 637
Query: 603 YSDFLSASPEENEKFVTVDVDRLNHERQISAAQSQASVDAFRHVFRNIQSLADKHACKDN 662
++ L A P +TV R E +++ ++A DA + A+K N
Sbjct: 638 QANKLDAEPG-----MTV---RETFESKVNKVLNKARDDAGKK--------AEKSLKIYN 681
Query: 663 SFLAMFKAGSKGNLLKLVQHSMCLGLQHSLVRLSYRIPRELSCAGWNSQKGLHSMEMSSD 722
+ M AGSKG+ + + Q + C+G Q+ + RIP G+ + H + D
Sbjct: 682 NVKQMVIAGSKGSFINISQMTACVGQQNVEGK---RIP-----YGFRYRTLPH---FTKD 730
Query: 723 TLEPKQSYIAHAVVESSFLTGLNPLECFVHSVTNRDSSFSDNADL--PGTLTRRLMFFMR 780
P+ + VE+S+L GL+P E F H++ R+ G + RRL+ +
Sbjct: 731 DHSPE----SRGFVENSYLRGLSPQEFFFHAMGGREGLIDTAVKTAETGYIQRRLVKALE 786
Query: 781 DMYDAYDGTVRNLYGNQLIQFSY 803
D+ YDGTVRN G+ ++QF Y
Sbjct: 787 DVMVKYDGTVRNSLGH-VVQFVY 808
>gb|AAC47792.2| RNA polymerase II large subunit [Leishmania major]
Length = 1663
Score = 153 bits (387), Expect = 2e-35
Identities = 138/550 (25%), Positives = 249/550 (45%), Gaps = 63/550 (11%)
Query: 272 LELSEIGIPCQIAEALQVSEYVNRQNRQNLLYCCELRLLEKGQINVRRNGNPVVLYKKED 331
+++ E+G+P +A L E VN N++ L + +R NGN L +D
Sbjct: 344 IDVDEVGVPFSVAMTLTFPERVNVINKKRLTEFVQRTTYPSANYIIRPNGNVTKLALVKD 403
Query: 332 -----LQIGDIFYRPLVDGDKVLINRPPSIHQHSMIALTVRVLPISSVVSINPICCSPLR 386
L +GD+ R ++DGD VL NR P++H+ SM+ VRVL ++ +N C +P
Sbjct: 404 RSAVHLDVGDVVERHVIDGDVVLFNRQPTLHRMSMMGHRVRVLNYNTF-RLNLSCTTPYN 462
Query: 387 GDFDGDCLHGYIPQSVGARVELNELVALDRQLINGQSGGNLLSLSQDSLTAAHLLLEDGV 446
DFDGD ++ ++PQS+ + EL E++ + + ++ + + QDS+ ++ L E
Sbjct: 463 ADFDGDEMNLHVPQSLLTKAELIEMMMVPKNFVSPNKSAPCMGIVQDSVLGSYKLTEKDT 522
Query: 447 GFNIYQVQQLEMLCNK-ELTSPAIFKAPSSNTPFWSGKQLFSMLLPSKFDYA-------F 498
+ Y + + + + +L P I K P W+GKQ+FS++LP A F
Sbjct: 523 FLDKYFIAERPLWLDLWQLPIPTILKP----RPLWTGKQIFSLILPEVNHPASPHDKPPF 578
Query: 499 PSND--VFVKDGELISCSESSGWLRDSENNVFQSLV-EHFQGKILDVLHGAQKALCEWLS 555
P ND + ++ G+L+ + + G + + ++ + E ++ ++G Q+ +
Sbjct: 579 PHNDSKIMIQRGQLLGGAITKGVVGAAPGSLIHVIFNERGSDEVAKFINGVQRITTYFNY 638
Query: 556 MTGFSVSLSDLYLSSDSYARKNMMEEISYGLRVAEQACDFNQLLVDHYSDFLSASPEENE 615
FSV + D + A ++E++ L Q+ + ++ A +
Sbjct: 639 CFAFSVGVQD------TVADATTLKEMNNVLHKTRQSVEKIGAAANNGKLTRKAGMSLLQ 692
Query: 616 KFVTVDVDRLNHERQISAAQSQASVDAFRHVFRNIQSLADKHACKDNSFLAMFKAGSKGN 675
F E +++A ++ +A + N++ + NSF M +AGSKG+
Sbjct: 693 SF----------EADVNSALNKCREEAAKKALSNVR--------RTNSFKVMIEAGSKGS 734
Query: 676 LLKLVQHSMCLGLQHSLVRLSYRIPRELSCAGWNSQKGLHSMEMSSDTLEPKQSYIAHAV 735
L + Q ++ +G Q+ RIP G+ + H M D E +
Sbjct: 735 DLNICQIAVFVGQQNVA---GSRIP-----FGFRRRTLPHFM--LDDYGETSRGMATRGY 784
Query: 736 VESSFLTGLNPLECFVHSVTNRDSSFSDNADLPGT--LTRRLMFFMRDMYDAYDGTVRNL 793
VE GL P E + H++ R+ T L R+L+ + D++ +YDGTVRN
Sbjct: 785 VE-----GLQPHEFYFHTMAGREGLIDTAVKTSDTGYLQRKLVKALEDVHASYDGTVRNA 839
Query: 794 YGNQLIQFSY 803
+LIQ +Y
Sbjct: 840 -NQELIQLAY 848
>gb|AAA50229.1| RNA polymerase II, largest subunit
Length = 1343
Score = 151 bits (381), Expect = 1e-34
Identities = 155/579 (26%), Positives = 256/579 (43%), Gaps = 81/579 (13%)
Query: 272 LELSEIGIPCQIAEALQVSEYVNRQNRQNLLYCCE--LRLLEKGQINVRRNGNPVVLY-- 327
L + ++G+P IA L E V N + + + +R NG + L
Sbjct: 287 LRVDQVGVPRSIAHNLTFPELVTPFNIDVMQERVRRGANVYPGAKYIIRDNGERIDLRFH 346
Query: 328 -KKEDL--QIGDIFYRPLVDGDKVLINRPPSIHQHSMIALTVRVLPISSVVSINPICCSP 384
K DL QIG R + D D V+ NR P++H+ SM+ V+VLP S+ +N +P
Sbjct: 347 PKASDLHLQIGYKVERHMQDNDVVIFNRQPTLHKMSMMCHRVKVLPWSTF-RMNLSVTTP 405
Query: 385 LRGDFDGDCLHGYIPQSVGARVELNELVALDRQLINGQSGGNLLSLSQDSLTAAHLLLED 444
DFDGD ++ ++PQS+ R E+ L A+ R +I Q+ ++ + QD+LTA + +
Sbjct: 406 YNADFDGDEMNLHLPQSLETRAEIMNLCAVPRMIITPQANRPVMGIVQDTLTAVRKMTKR 465
Query: 445 GVGFNIYQVQQLEMLC---NKELTSPAIFKAPSSNTPFWSGKQLFSMLLPSK-------- 493
V Q+ L M + + PAI K P W+GKQ+FS+++P +
Sbjct: 466 DVFLTRAQMMHLLMFLPTWDGRMPQPAIIKP----EPLWTGKQIFSLVIPGRVNVIRTHS 521
Query: 494 ----------FDYAFPSN-DVFVKDGELISCSESSGWLRDSENNVFQSLVEHFQGKILDV 542
+ + P + V ++DGELIS L S ++ + ++
Sbjct: 522 THPDGEDSGPYKWISPGDTKVLIEDGELISGILCKKTLGTSAGSLVHIVFLEMGFEVAGE 581
Query: 543 LHG-AQKALCEWLSMTGFSVSLSDLYLSSDSYARKNMMEEISYGLRVAEQACDFNQLLVD 601
L+G Q + WL + G S+ + D +Y EI +R A+ D +++
Sbjct: 582 LYGNIQTVVNNWLLIEGHSIGIGDTIADQQTY------HEIQETIRKAK--ADVIEVIEK 633
Query: 602 HYSDFLSASPEEN-EKFVTVDVDR-LNHERQISAAQSQASVDAFRHVFRNIQSLADKHAC 659
++D L +P + V+R LN R + +++Q S+ F
Sbjct: 634 AHNDELEPTPGNTLRQTFENQVNRILNDARDKTGSKAQKSLSEF---------------- 677
Query: 660 KDNSFLAMFKAGSKGNLLKLVQHSMCLGLQHSLVRLSYRIPRELSCAGWNSQKGLHSMEM 719
N+F AM AGSKG+ + + Q C+G Q++ + RIP G+ + H ++
Sbjct: 678 --NNFKAMVVAGSKGSKINISQVIACVGQQNAEGK---RIP-----FGFRYRTLPHFIK- 726
Query: 720 SSDTLEPKQSYIAHAVVESSFLTGLNPLECFVHSVTNRDSSFSDNADL--PGTLTRRLMF 777
D P+ + VE+S+L GL P E + H++ R+ G + RRL+
Sbjct: 727 --DDYGPE----SRGFVENSYLAGLTPSEFYFHAMGGREGLIDTAVKTAETGYIQRRLIK 780
Query: 778 FMRDMYDAYDGTVRNLYGNQLIQFSYDAEEDSSCDSYFR 816
M + YDGTVRN QL+Q Y + +C F+
Sbjct: 781 AMESVMVKYDGTVRNQV-EQLVQLGYGEDGLDACHVEFQ 818
>gb|AAC03137.3| RNA polymerase II largest subunit [Mastigoproctus giganteus]
Length = 887
Score = 150 bits (378), Expect = 3e-34
Identities = 155/574 (27%), Positives = 258/574 (44%), Gaps = 97/574 (16%)
Query: 272 LELSEIGIPCQIAEALQVSEYVNRQNRQNLLYCCELRLLEKGQIN-------VRRNGNPV 324
L + E+GIP IA+ L E V N + L+ +G +R NG +
Sbjct: 12 LRIDEVGIPRSIAQNLTFPEIVTPFNIDKMH-----ELVRRGNNQYPGAKYIIRDNGERI 66
Query: 325 VLY---KKEDL--QIGDIFYRPLVDGDKVLINRPPSIHQHSMIALTVRVLPISSVVSINP 379
L K DL Q G R + +GD V+ NR P++H+ SM+ +RVLP S+ +N
Sbjct: 67 DLRFHPKASDLHLQCGYKVERHVKNGDVVIFNRQPTLHKMSMMGHKIRVLPWSTF-RLNL 125
Query: 380 ICCSPLRGDFDGDCLHGYIPQSVGARVELNELVALDRQLINGQSGGNLLSLSQDSLTAAH 439
+P DFDGD ++ ++PQS+ R E+ EL + RQ+I QS ++ + QD+LTA
Sbjct: 126 SVTTPYNADFDGDEMNLHVPQSLETRAEVQELALVPRQIITPQSNKPVMGIVQDTLTAVR 185
Query: 440 LLLEDGVGFNIYQVQQLEM---LCNKELTSPAIFKAPSSNTPFWSGKQLFSMLLPSK--- 493
+ + V Q+ L M + + ++ PA+ K P W+GKQLFS+++P
Sbjct: 186 KMTKRDVFLEKDQMMNLLMFLPIWDGKMPMPAVLKP----KPLWTGKQLFSLIIPDNVNL 241
Query: 494 ---------------FDYAFPSN-DVFVKDGELIS---CSESSGWLRDSENNVFQSLVEH 534
+ + P + V ++ G+LIS C ++ G S +V + + H
Sbjct: 242 IRTHSTHPDDEDDGPYKWISPGDTKVLIEHGQLISGIVCKKTVGSASGSLMHVVFAELGH 301
Query: 535 FQGKILDVLHG-AQKALCEWLSMTGFSVSLSDLYLSSDSYARKNMMEEISYGLRVAEQAC 593
++ +G Q + WL + G ++ + D +Y +I ++ A+
Sbjct: 302 ---EVAGAFYGHIQTVVNNWLLLEGHTIGIGDTIADPQTYI------DIQNTIKKAKH-- 350
Query: 594 DFNQLLVDHYSDFLSASPEEN-EKFVTVDVDR-LNHERQISAAQSQASVDAFRHVFRNIQ 651
D +++ ++D L +P + V+R LN R + A +Q S+ F
Sbjct: 351 DVIEVIEKAHNDELEPTPGNTLRQTFENQVNRILNDARDKTGASAQKSLSEF-------- 402
Query: 652 SLADKHACKDNSFLAMFKAGSKGNLLKLVQHSMCLGLQHSLVRLSYRIPRELSCAGWNSQ 711
N+F AM +G+KG+ + + Q C+G Q+ + RIP G+ +
Sbjct: 403 ----------NNFKAMVVSGAKGSKINISQVIACVGQQNVEGK---RIP-----FGFRKR 444
Query: 712 KGLHSMEMSSDTLEPKQSYIAHAVVESSFLTGLNPLECFVHSVTNRDSSFSDNADL--PG 769
H ++ D P+ + VE+S+L GL P E F H++ R+ G
Sbjct: 445 TLPHFIK---DDYGPE----SRGFVENSYLAGLTPSEFFFHAMGGREGLIDTAVKTAETG 497
Query: 770 TLTRRLMFFMRDMYDAYDGTVRNLYGNQLIQFSY 803
+ RRL+ M + YDGT+RN G Q+IQ Y
Sbjct: 498 YIQRRLIKAMESVMATYDGTIRNSTG-QVIQLRY 530
>gb|AAF26656.2| RNA polymerase II largest subunit [Scolopendra polymorpha]
Length = 734
Score = 150 bits (378), Expect = 3e-34
Identities = 153/569 (26%), Positives = 252/569 (43%), Gaps = 87/569 (15%)
Query: 272 LELSEIGIPCQIAEALQVSEYVNRQNRQNLLYCCELRLLEKGQIN-------VRRNGNPV 324
L + ++G+P IA+ L E V N + L+++G +R NG +
Sbjct: 24 LRIDQVGVPRSIAQNLTFPEIVTPFNIDKMQ-----ELVQRGNNQYPGAKYIIRDNGERI 78
Query: 325 VLY---KKEDL--QIGDIFYRPLVDGDKVLINRPPSIHQHSMIALTVRVLPISSVVSINP 379
L K DL Q G R + DGD V+ NR P++H+ SM+ +RVLP S+ +N
Sbjct: 79 DLRFHPKPSDLHLQCGYKVERHVRDGDVVIFNRQPTLHKMSMMGHHIRVLPWSTF-RMNL 137
Query: 380 ICCSPLRGDFDGDCLHGYIPQSVGARVELNELVALDRQLINGQSGGNLLSLSQDSLTAAH 439
+P DFDGD ++ ++PQS+ R E+ EL + RQ+I QS ++ + QD+LTA
Sbjct: 138 SVTTPYNADFDGDEMNLHVPQSMETRAEIEELAIVPRQIITPQSNRPVMGIVQDTLTAVR 197
Query: 440 LLLEDGVGFNIYQVQQLEM---LCNKELTSPAIFKAPSSNTPFWSGKQLFSMLLPS---- 492
+ + V Q+ L M + + ++ PAI K P W+GKQLFS+++P
Sbjct: 198 KMTKRDVFLEKDQMMNLLMFLPIWDGKMPMPAILKP----KPLWTGKQLFSLIIPGAVNV 253
Query: 493 -KFDYAFPSND--------------VFVKDGELISCSESSGWLRDSENNVFQSLVEHFQG 537
+ Y P ++ V V+ G+LIS L S ++ ++
Sbjct: 254 IRTHYTHPDDEDDSPYKWISPGDTKVLVEHGKLISGILCKKTLGTSAGSLLHIVMLELGW 313
Query: 538 KILDVLH-GAQKALCEWLSMTGFSVSLSDLYLSSDSYARKNMMEEISYGLRVAEQACDFN 596
+I + Q + WL + G ++ + D +Y +I ++ A+ D
Sbjct: 314 EIAGTFYWHIQMVINNWLLLEGHTIGIGDTIADPQTYI------DIQNSIKKAKH--DVI 365
Query: 597 QLLVDHYSDFLSASPEENEKFVTVDVDRLNHERQISAAQSQASVDAFRHVFRNIQSLADK 656
++ ++D L +P + R E Q++ + A S A K
Sbjct: 366 DVIEKAHNDELEPTPG--------NTLRQTFENQVNRILNDAR--------DKTGSSAQK 409
Query: 657 HACKDNSFLAMFKAGSKGNLLKLVQHSMCLGLQHSLVRLSYRIPRELSCAGWNSQKGLHS 716
+ N+F AM +G+KG+ + + Q C+G Q+ + RIP G+ + H
Sbjct: 410 SLSEYNNFKAMVVSGAKGSKINISQVIACVGQQNVEGK---RIP-----FGFRKRTLPHF 461
Query: 717 MEMSSDTLEPKQSYIAHAVVESSFLTGLNPLECFVHSVTNRDSSFSDNADL--PGTLTRR 774
++ D P+ + VE+S+L GL P E + H++ R+ G + RR
Sbjct: 462 IK---DDYGPE----SRGFVENSYLAGLTPSEFYFHAMGGREGLIDTAVKTAETGYIQRR 514
Query: 775 LMFFMRDMYDAYDGTVRNLYGNQLIQFSY 803
L+ M + YDGTVRN G QLIQ Y
Sbjct: 515 LIKAMESIMITYDGTVRNSVG-QLIQLRY 542
>emb|CAG98018.1| unnamed protein product [Kluyveromyces lactis NRRL Y-1140]
gi|50310581|ref|XP_455310.1| unnamed protein product
[Kluyveromyces lactis]
Length = 1720
Score = 149 bits (377), Expect = 4e-34
Identities = 157/564 (27%), Positives = 248/564 (43%), Gaps = 86/564 (15%)
Query: 272 LELSEIGIPCQIAEALQVSEYVNRQNRQNLLYCCELRLLEKG-------QINVRRNGNPV 324
L+L ++G+P IA+ L E V N L +L+ G + +R +G+ +
Sbjct: 359 LDLDQVGVPKSIAKTLTYPEVVTPYNIDRLT-----QLVRNGPNEHPGAKYVIRESGDRI 413
Query: 325 VL-YKKE----DLQIGDIFYRPLVDGDKVLINRPPSIHQHSMIALTVRVLPISSVVSINP 379
L Y K LQ G R + D D VL NR PS+H+ SM+A V+V+P S+ +N
Sbjct: 414 DLRYSKRAGDIQLQYGWKVERHITDNDPVLFNRQPSLHKMSMMAHRVKVMPYSTF-RLNL 472
Query: 380 ICCSPLRGDFDGDCLHGYIPQSVGARVELNELVALDRQLINGQSGGNLLSLSQDSLTAAH 439
SP DFDGD ++ ++PQS R EL++L A+ Q+++ QS + + QD+L
Sbjct: 473 SVTSPYNADFDGDEMNLHVPQSEETRAELSQLCAVPLQIVSPQSNKPCMGIVQDTLCGIR 532
Query: 440 LLLEDGVGFNIYQVQQLEMLC-----NKELTSPAIFKAPSSNTPFWSGKQLFSMLLPS-- 492
+ + QV L ML + + +PAI K P WSGKQ+ SM +P+
Sbjct: 533 KMTLRDTFIELDQV--LNMLYWIPDWDGIIPTPAILKP----VPLWSGKQVLSMAIPNGI 586
Query: 493 ---KFD----YAFPS-NDVFVKDGELISCSESSGWLRDSENNVFQSLVEHFQGKILDVLH 544
+FD + P N + + DG++I + S + + +I L
Sbjct: 587 HLQRFDDGTTFLSPKDNGMLIIDGKIIFGVVDKKTVGSSSGGLIHVVTREKGPEICARLF 646
Query: 545 G-AQKALCEWLSMTGFSVSLSDLYLSSDSYARKNMMEEISYGLRVAEQACDFNQLLVDHY 603
QK + WL GFS+ + D + A + M EI+ + VA++ + + +
Sbjct: 647 SNIQKVVNYWLLHNGFSIGIGD------TIADEKTMREITEAIAVAKKKVE--DVTKEAQ 698
Query: 604 SDFLSASPEEN--EKFVTVDVDRLNHERQISAAQSQASVDAFRHVFRNIQSLADKHACKD 661
++ L+A E F V LN R + ++ N++ L
Sbjct: 699 ANLLTAKHGMTLRESFEDNVVRYLNEARDKAGRSAEV----------NLKDL-------- 740
Query: 662 NSFLAMFKAGSKGNLLKLVQHSMCLGLQHSLVRLSYRIPRELSCAGWNSQKGLHSMEMSS 721
N+ M AGSKG+ + + Q S C+G Q + + G+ + H S
Sbjct: 741 NNVKQMVSAGSKGSFINIAQMSACVGQQS--------VEGKRIAFGFADRTLPH---FSK 789
Query: 722 DTLEPKQSYIAHAVVESSFLTGLNPLECFVHSVTNRDSSFSDNADLP--GTLTRRLMFFM 779
D P+ VE+S+L GL P E F H++ R+ G + RRL+ +
Sbjct: 790 DDYSPESK----GFVENSYLRGLTPQEFFFHAMGGREGLIDTAVKTAETGYIQRRLVKAL 845
Query: 780 RDMYDAYDGTVRNLYGNQLIQFSY 803
D+ YDGT RN GN +IQF Y
Sbjct: 846 EDIMVHYDGTTRNSLGN-VIQFIY 868
Score = 43.9 bits (102), Expect = 0.028
Identities = 22/73 (30%), Positives = 38/73 (51%), Gaps = 10/73 (13%)
Query: 46 LGLPNSSYGCTTCGSKDRKSCEGHFGAIKFPFTILHPYFMAEIAEILQKICPAC------ 99
LG + +Y C TCG + C GHFG I+ + H F+++I ++ + +C C
Sbjct: 58 LGSIDRNYKCQTCG-EGMAECPGHFGHIELAKPVFHIGFLSKIKKVCESVCMHCGKLLLD 116
Query: 100 ---KSIRQEIRVK 109
+ +RQ I++K
Sbjct: 117 EYNEQMRQAIKIK 129
>gb|AAF26651.2| RNA polymerase II largest subunit [Polyxenus fasciculatus]
Length = 751
Score = 149 bits (375), Expect = 6e-34
Identities = 155/574 (27%), Positives = 255/574 (44%), Gaps = 97/574 (16%)
Query: 272 LELSEIGIPCQIAEALQVSEYVNRQNRQNLLYCCELRLLEKGQIN-------VRRNGNPV 324
L + ++G+P IA+ L E V N + L+ +G +R NG +
Sbjct: 24 LRIDQVGVPRSIAQNLTFPEIVTPFNIDKMQ-----ELVRRGNSQYPGAKYIIRDNGERI 78
Query: 325 VLY---KKEDL--QIGDIFYRPLVDGDKVLINRPPSIHQHSMIALTVRVLPISSVVSINP 379
L K DL Q G R + DGD V+ NR P++H+ SM+ +RV P S+ +N
Sbjct: 79 DLRFHPKPSDLHLQCGYRVERHVRDGDVVIFNRQPTLHKMSMMGHHIRVFPWSTF-RMNL 137
Query: 380 ICCSPLRGDFDGDCLHGYIPQSVGARVELNELVALDRQLINGQSGGNLLSLSQDSLTAAH 439
+P DFDGD ++ ++PQS+ R E+ EL + RQ+I QS ++ + QD+LTA
Sbjct: 138 SVTTPYNADFDGDEMNLHVPQSMETRAEIEELAIVPRQIITPQSNRPVMGIVQDTLTAVR 197
Query: 440 LLLEDGVGFNIYQVQQLEM---LCNKELTSPAIFKAPSSNTPFWSGKQLFSMLLPSK--- 493
+ + V + Q+ + M + + ++ PAI K P W+GKQ+FS+++P
Sbjct: 198 KMTKRDVFLDKDQMMNILMFLPIWDGKMPQPAILKP----KPVWTGKQVFSLIIPGNVNM 253
Query: 494 ---------------FDYAFPSN-DVFVKDGEL---ISCSESSGWLRDSENNVFQSLVEH 534
+ + P + V V+ GEL I C +S G S ++ ++
Sbjct: 254 IRTHSTHPDDEDDGPYKWISPGDTKVLVEHGELMCGILCKKSLG---TSAGSLLHIVMLE 310
Query: 535 FQGKILDVLHG-AQKALCEWLSMTGFSVSLSDLYLSSDSYARKNMMEEISYGLRVAEQAC 593
+ + + Q + WL + G ++ + D +Y EI +R A+Q
Sbjct: 311 LGWETAGLFYSHIQTVVNNWLLLEGHTIGIGDTIADQQTY------HEIQETIRKAKQ-- 362
Query: 594 DFNQLLVDHYSDFLSASPEEN-EKFVTVDVDR-LNHERQISAAQSQASVDAFRHVFRNIQ 651
D +++ ++D L +P + V+R LN R + +Q S+ F
Sbjct: 363 DVIEVIEKAHNDELEPTPGNTLRQTFENQVNRILNDARDKTGGSAQRSLSEF-------- 414
Query: 652 SLADKHACKDNSFLAMFKAGSKGNLLKLVQHSMCLGLQHSLVRLSYRIPRELSCAGWNSQ 711
N+F AM +G+KG+ + + Q C+G Q+ + RIP G+ +
Sbjct: 415 ----------NNFKAMVVSGAKGSKINISQVIACVGQQNVEGK---RIP-----FGFRKR 456
Query: 712 KGLHSMEMSSDTLEPKQSYIAHAVVESSFLTGLNPLECFVHSVTNRDSSFSDNADL--PG 769
H ++ D P+ + VE+S+L GL P E F H++ R+ G
Sbjct: 457 TLPHFIK---DDYGPE----SRGFVENSYLAGLTPSEFFFHAMGGREGLIDTAVKTAETG 509
Query: 770 TLTRRLMFFMRDMYDAYDGTVRNLYGNQLIQFSY 803
+ RRL+ M + YDGTVRN G QLIQ Y
Sbjct: 510 YIQRRLIKAMESVMVTYDGTVRNSVG-QLIQLRY 542
>gb|AAA50227.1| RNA polymerase II, largest subunit
Length = 1337
Score = 149 bits (375), Expect = 6e-34
Identities = 152/573 (26%), Positives = 257/573 (44%), Gaps = 95/573 (16%)
Query: 272 LELSEIGIPCQIAEALQVSEYVNRQNRQNLLYCCELRLLEKG-------QINVRRNGNPV 324
L + ++G+P IA+ L E V N + L L+++G + +R G+ +
Sbjct: 280 LRIDQVGVPRSIAQNLTFPEIVTPFNIERLT-----ELVKRGANQYPGAKFILRETGDRI 334
Query: 325 VLY---KKEDL--QIGDIFYRPLVDGDKVLINRPPSIHQHSMIALTVRVLPISSVVSINP 379
L K DL Q G R + D D V+ NR P++H+ SM+ V++LP S+ +N
Sbjct: 335 DLRYHPKSTDLHLQFGYRVERHMQDNDYVIFNRQPTLHKMSMMCHRVKILPWSTF-RLNL 393
Query: 380 ICCSPLRGDFDGDCLHGYIPQSVGARVELNELVALDRQLINGQSGGNLLSLSQDSLTAAH 439
+P DFDGD ++ ++ QS+ R E+++L ++ R +I Q+ ++ + QDSLTA +
Sbjct: 394 SVTTPYNADFDGDEMNLHLAQSLETRAEISQLASVKRMIITPQANRPVMGIVQDSLTAVN 453
Query: 440 LLLEDGVGFNIYQVQQLEMLC---NKELTSPAIFKAPSSNTPFWSGKQLFSMLLPSKFDY 496
+ ++ + M +L PAI K + W+GKQLFS+++P + +
Sbjct: 454 KMTRRDTFITKDEIMNILMYLPGWAGKLPQPAILKPRA----LWTGKQLFSIIIPGRINV 509
Query: 497 -----AFPSND--------------VFVKDGELIS---CSESSGWLRDSENNVFQSLVEH 534
P ++ V V+DG+L+S C +S G + + Q ++ H
Sbjct: 510 IRTHSTHPDDEDRGPHKWISPGDTKVLVEDGKLLSGILCKKSLG----ASSGSLQHIIHH 565
Query: 535 FQGK--ILDVLHGAQKALCEWLSMTGFSVSLSDLYLSSDSYARKNMMEEISYGLRVAEQA 592
G D Q WL +TG ++ ++D + +Y+ +I ++ A+
Sbjct: 566 ELGSDATADFYAYIQMVTNHWLLVTGHTIGIADTIADAKTYS------DIQTAIKKAKS- 618
Query: 593 CDFNQLLVDHYSDFLSASPEENEKFVTVDVDRLNHERQISAAQSQASVDAFRHVFRNIQS 652
D +++ ++D L P + R E Q++ + A S
Sbjct: 619 -DVVEVIEKAHNDELEPMPG--------NTLRQTFENQVNRILNDAR--------DKTGS 661
Query: 653 LADKHACKDNSFLAMFKAGSKGNLLKLVQHSMCLGLQHSLVRLSYRIPRELSCAGWNSQK 712
LA K + N+F +M AGSKGN + + Q C+G Q+ + RIP G+ +
Sbjct: 662 LAQKSLSEFNNFKSMVVAGSKGNKINISQVIACVGQQNVEGK---RIP-----FGFRQRT 713
Query: 713 GLHSMEMSSDTLEPKQSYIAHAVVESSFLTGLNPLECFVHSVTNRDSSFSDNADL--PGT 770
H ++ D P+ + VE+S+L GL P E F H++ R+ G
Sbjct: 714 LPHFIK---DDYGPE----SRGFVENSYLAGLTPTEFFFHAMGGREGLIDTAVKTAETGY 766
Query: 771 LTRRLMFFMRDMYDAYDGTVRNLYGNQLIQFSY 803
+ RRL+ M + YDGTVRN QLIQ Y
Sbjct: 767 IQRRLIKAMESVMVKYDGTVRNQI-EQLIQLRY 798
Database: nr
Posted date: Jul 5, 2005 12:34 AM
Number of letters in database: 863,360,394
Number of sequences in database: 2,540,612
Lambda K H
0.328 0.141 0.432
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 1,634,373,392
Number of Sequences: 2540612
Number of extensions: 67453678
Number of successful extensions: 179402
Number of sequences better than 10.0: 896
Number of HSP's better than 10.0 without gapping: 688
Number of HSP's successfully gapped in prelim test: 208
Number of HSP's that attempted gapping in prelim test: 176128
Number of HSP's gapped (non-prelim): 1789
length of query: 1025
length of database: 863,360,394
effective HSP length: 138
effective length of query: 887
effective length of database: 512,755,938
effective search space: 454814517006
effective search space used: 454814517006
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.7 bits)
S2: 80 (35.4 bits)
Medicago: description of AC146573.11