BLAST2 result
BLASTP 2.2.2 [Dec-14-2001]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= AC144431.4 - phase: 0 /pseudo
(1510 letters)
Database: nr
2,540,612 sequences; 863,360,394 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
dbj|BAB10944.1| DNA polymerase alpha 1 [Arabidopsis thaliana] gi... 1545 0.0
dbj|BAD81999.1| putative DNA polymerase alpha catalytic subunit ... 1519 0.0
sp|O48653|DPOA_ORYSA DNA polymerase alpha catalytic subunit gi|2... 1468 0.0
ref|NP_915661.1| putative DNA polymerase alpha catalytic subunit... 1422 0.0
dbj|BAD92011.1| DNA polymerase alpha catalytic subunit [Gallus g... 695 0.0
dbj|BAD92010.1| DNA polymerase alpha catalytic subunit [Caiman c... 694 0.0
gb|AAG35630.1| DNA polymerase alpha [Xenopus laevis] gi|45476976... 692 0.0
gb|EAK85452.1| hypothetical protein UM04529.1 [Ustilago maydis 5... 686 0.0
gb|AAP13534.1| polymerase (DNA directed), alpha [Homo sapiens] g... 685 0.0
emb|CAA29920.1| unnamed protein product [Homo sapiens] gi|839399... 685 0.0
dbj|BAD92009.1| DNA polymerase alpha catalytic subunit [Iguana i... 685 0.0
dbj|BAD92007.1| DNA polymerase alpha catalytic subunit [Ambystom... 672 0.0
emb|CAA09720.1| DNA polymerase alpha subunit I [Rattus norvegicu... 672 0.0
ref|XP_416792.1| PREDICTED: similar to polymerase (DNA directed)... 670 0.0
dbj|BAD92008.1| DNA polymerase alpha catalytic subunit [Trachemy... 667 0.0
dbj|BAC76767.1| DNA polymerase alpha catalytic subunit [Coprinop... 662 0.0
gb|AAT68051.1| DNA polymerase alpha [Danio rerio] 661 0.0
gb|AAP45775.1| DNA polymerase catalytic subunit alpha [Stylonych... 650 0.0
gb|AAP45773.1| DNA polymerase catalytic subunit alpha [Stylonych... 649 0.0
gb|AAP45776.1| DNA polymerase catalytic subunit alpha [Stylonych... 649 0.0
>dbj|BAB10944.1| DNA polymerase alpha 1 [Arabidopsis thaliana]
gi|15240200|ref|NP_201511.1| DNA-directed DNA polymerase
alpha catalytic subunit, putative [Arabidopsis thaliana]
Length = 1492
Score = 1545 bits (3999), Expect = 0.0
Identities = 771/1131 (68%), Positives = 925/1131 (81%), Gaps = 11/1131 (0%)
Query: 382 VWQGTLYQSCCVVVKNMQRCVYAIPSHPLHSTNEMIQLEKDVQESRISPADFRKKLQDAV 441
V G Y+SCCVVVKN+QRCVYAIP+ + ++E+I LE++V++SR+SP FR KL +
Sbjct: 370 VKMGDTYKSCCVVVKNIQRCVYAIPNDSIFPSHELIMLEQEVKDSRLSPESFRGKLHEMA 429
Query: 442 SDTKNEIAKHLVDLGVSSFSMAPVKRKYAFERTDIPAGENYVVKINYLFKDTALPVDLKG 501
S KNEIA+ L+ L VS+FSMAPVKR YAFER D+PAGE YV+KINY FKD LP DLKG
Sbjct: 430 SKLKNEIAQELLQLNVSNFSMAPVKRNYAFERPDVPAGEQYVLKINYSFKDRPLPEDLKG 489
Query: 502 KSFCALLGARNSALELFLIKRKIKGPSWLQVSNFSTCSASQRVSWCKFEVIVDSPKDIRA 561
+SF ALLG+ SALE F++KRKI GP WL++S+FSTCS S+ VSWCKFEV V SPKDI
Sbjct: 490 ESFSALLGSHTSALEHFILKRKIMGPCWLKISSFSTCSPSEGVSWCKFEVTVQSPKDITI 549
Query: 562 SSPSSSKITLVNPPVVVTAINLKTTINEKQNINEIVSASVVSCNMVKIDTPMLASEWKRP 621
S+ +V+PP VVTAINLKT +NEKQNI+EIVSASV+ + KID PM A E KR
Sbjct: 550 LV---SEEKVVHPPAVVTAINLKTIVNEKQNISEIVSASVLCFHNAKIDVPMPAPERKRS 606
Query: 622 GMLTHFTVIRKLDGNIFPMGFNTEVTDRNIKAGSNVLCVESSERALLNRLMLQLHKMDSD 681
G+L+HFTV+R +G +P+G+ EV+DRN K G NVL +E+SERALLNRL L+L+K+DSD
Sbjct: 607 GILSHFTVVRNPEGTGYPIGWKKEVSDRNSKNGCNVLSIENSERALLNRLFLELNKLDSD 666
Query: 682 VLVGHNISGFDLDVLLHRSQACRVPSSMWSKLGRLNRSTMPKLDRRGKTFGFGADPAIMS 741
+LVGHNISGFDLDVLL R+QAC+V SSMWSK+GRL RS MPKL + +G GA P +MS
Sbjct: 667 ILVGHNISGFDLDVLLQRAQACKVQSSMWSKIGRLKRSFMPKL-KGNSNYGSGATPGLMS 725
Query: 742 CVAGRLLCDTYLCSRDLLKEVSYSLTHLAKTQLNQSRKEVAPHEVPKMFQTAKSLMELIE 801
C+AGRLLCDT LCSRDLLKEVSYSLT L+KTQLN+ RKE+AP+++PKMFQ++K+L+ELIE
Sbjct: 726 CIAGRLLCDTDLCSRDLLKEVSYSLTDLSKTQLNRDRKEIAPNDIPKMFQSSKTLVELIE 785
Query: 802 YGETDAWLSMELMFYLSVLPLTRQLTNLSGNLWGKTLQGARAQRVEYLLLHEFHKKKYIV 861
GETDAWLSMELMF+LSVLPLT QLTN+SGNLWGKTLQGARAQR+EY LLH FH KK+I+
Sbjct: 786 CGETDAWLSMELMFHLSVLPLTLQLTNISGNLWGKTLQGARAQRIEYYLLHTFHSKKFIL 845
Query: 862 PDKFSNYAKETKLTKRRVTHGVDDGNFDDADINDANYHNDASESDHKKNKKAASYAGGLV 921
PDK S KE K +KRR+ + +D N D+ D D ND S+ K KK +YAGGLV
Sbjct: 846 PDKISQRMKEIKSSKRRMDYAPEDRNVDELDA-DLTLENDPSKGS--KTKKGPAYAGGLV 902
Query: 922 LEPKKGLYDKYILLLDFNSLYPSIIQEYNICFTTVERSSDDSFPRLPSSKTTGVLPELLK 981
LEPK+GLYDKY+LLLDFNSLYPSIIQEYNICFTT+ RS +D PRLPSS+T G+LP+L++
Sbjct: 903 LEPKRGLYDKYVLLLDFNSLYPSIIQEYNICFTTIPRS-EDGVPRLPSSQTPGILPKLME 961
Query: 982 KLVKLRREKKTWMKTASGLKRQQLDIEQQALKLTANSMYGCLGFSNSRFYAKPLAELITL 1041
LV +R+ K MK +GLK +LDI QQALKLTANSMYGCLGFSNSRFYAKPLAELITL
Sbjct: 962 HLVSIRKSVKLKMKKETGLKYWELDIRQQALKLTANSMYGCLGFSNSRFYAKPLAELITL 1021
Query: 1042 QGREILQSTVDLVQNNLNLEVIYGDTDSIMIYSGLDDIAKATSISKKVIQEVNKKYRCLE 1101
QGR+ILQ TVDLVQN+LNLEVIYGDTDSIMI+SGLDDI + +I KVIQEVNKKYRCL+
Sbjct: 1022 QGRDILQRTVDLVQNHLNLEVIYGDTDSIMIHSGLDDIEEVKAIKSKVIQEVNKKYRCLK 1081
Query: 1102 IDLDGLYKRMLLLKKKKYAAVKVQFKDGTPYEVIERKGLDIVRRDWSLLAKDLGDFCLTQ 1161
ID DG+YKRMLLL+KKKYAAVK+QFKDG P E IERKG+D+VRRDWSLL+K++GD CL++
Sbjct: 1082 IDCDGIYKRMLLLRKKKYAAVKLQFKDGKPCEDIERKGVDMVRRDWSLLSKEIGDLCLSK 1141
Query: 1162 ILSGGSCEDVVESIHNSLMKVQEEMRNGQVALEKYVITKTLTKPPEAYPDAKNQPHVLVA 1221
IL GGSCEDVVE+IHN LMK++EEMRNGQVALEKYVITKTLTKPP AYPD+K+QPHV VA
Sbjct: 1142 ILYGGSCEDVVEAIHNELMKIKEEMRNGQVALEKYVITKTLTKPPAAYPDSKSQPHVQVA 1201
Query: 1222 QRLKQQGYTSGCSVGDTIPYVICCEQG-GSSGSATGIALRARHPDELKQEQGTWLIDIDY 1280
R++Q+GY G + DT+PY+IC EQG SS S+ GIA RARHPDE+K E WL+DIDY
Sbjct: 1202 LRMRQRGYKEGFNAKDTVPYIICYEQGNASSASSAGIAERARHPDEVKSEGSRWLVDIDY 1261
Query: 1281 YLSQQIHPVISRLCASIQGTSPERLADCLGLDTSKFQHKSSEA-SDDPTSSLLFAGDDEE 1339
YL+QQIHPV+SRLCA IQGTSPERLA+CLGLD SK++ KS++A S DP++SLLFA DEE
Sbjct: 1262 YLAQQIHPVVSRLCAEIQGTSPERLAECLGLDPSKYRSKSNDATSSDPSTSLLFATSDEE 1321
Query: 1340 SEKPTSSGTDESDYNFWRKLCCPKC-FENGAGRISAAMIANQVKRQAEKFVLMYYRGLLM 1398
S+KP + T+ESD FW KL CPKC E+ G IS AMIANQVKRQ + FV MYY+G+++
Sbjct: 1322 SKKPATPETEESDSTFWLKLHCPKCQQEDSTGIISPAMIANQVKRQIDGFVSMYYKGIMV 1381
Query: 1399 CDDETCKHTTRSVSFRLVGDSERGTVCPNYPRCNGHLNRKYTEADLYKQLSYFCHVFDTV 1458
C+DE+CKHTTRS +FRL+G+ ERGTVCPNYP CNG L RKYTEADLYKQLSYFCH+ DT
Sbjct: 1382 CEDESCKHTTRSPNFRLLGERERGTVCPNYPNCNGTLLRKYTEADLYKQLSYFCHILDTQ 1441
Query: 1459 CYIEKMEAKSRIPIEKELIKIRPIVDLAASTIQKIRDRCAFGWVKLQDLVV 1509
C +EKM+ RI +EK + KIRP V AA+ + RDRCA+GW++L D+V+
Sbjct: 1442 CSLEKMDVGVRIQVEKAMTKIRPAVKSAAAITRSSRDRCAYGWMQLTDIVI 1492
Score = 53.9 bits (128), Expect = 4e-05
Identities = 28/69 (40%), Positives = 44/69 (63%), Gaps = 2/69 (2%)
Query: 1 MADDDGSSRKRRPTRGPDATARSQALELLRSRRSNGPRSTTTP--QIRLENPIYDTIPED 58
M+ D+ + RR +RG +A++R LE L++ R G RS + IRL+ PI+DT+ ++
Sbjct: 1 MSGDNSTETGRRRSRGAEASSRKDTLERLKAIRQGGIRSASGGGYDIRLQKPIFDTVDDE 60
Query: 59 EYTALVASR 67
EY ALV+ R
Sbjct: 61 EYDALVSRR 69
>dbj|BAD81999.1| putative DNA polymerase alpha catalytic subunit [Oryza sativa
(japonica cultivar-group)]
Length = 1532
Score = 1519 bits (3932), Expect = 0.0
Identities = 763/1164 (65%), Positives = 924/1164 (78%), Gaps = 52/1164 (4%)
Query: 385 GTLYQSCCVVVKNMQRCVYAIPSHPLHSTNEMIQLEKDVQESRISPADFRKKLQDAVSDT 444
G + SCCVVVKNMQRC+YAIPS + + + +LEK+ S SP+ R L + S
Sbjct: 382 GKRFHSCCVVVKNMQRCIYAIPSSSIFPRDTISRLEKNSTTSDSSPS-LRASLHELASGL 440
Query: 445 KNEIAKHLVDLGVSSFSMAPVKRKYAFERTDIPAGENYVVKINYLFKDTALPVDLKGKSF 504
K+EIA L D VS+F+M PVKR YAFERTD+P GE YV+KINY +KD ALP DL+G+ F
Sbjct: 441 KSEIADKLSDFNVSNFAMTPVKRNYAFERTDLPNGEQYVLKINYPYKDPALPTDLRGQHF 500
Query: 505 CALLGARNSALELFLIKRKIKGPSWLQVSNFSTCSASQRVSWCKFEVIVDSPKDIRASSP 564
ALLG NSALEL LIKRKIKGPSWL +S F C A+QRVSWCKFEV VDSPKDI
Sbjct: 501 HALLGTNNSALELLLIKRKIKGPSWLSISKFLACPATQRVSWCKFEVTVDSPKDISVLMT 560
Query: 565 SSSKITLVNPPVVVTAINLKTTINEKQNINEIVSASVVSCNMVKIDTPMLASEWKRPGML 624
S+ TL PPVVV A+NLKT INEK N++EIVSASV+ C+ VKID+PM + +W++ GML
Sbjct: 561 ST---TLEVPPVVVAAVNLKTIINEKHNVHEIVSASVICCHRVKIDSPMRSEDWQKRGML 617
Query: 625 THFTVIRKLDGNIFPMGFNTEVTDRNIKAGSNVLCVESSERALLNRLMLQLHKMDSDVLV 684
+HFTV+RKL+G+IFP+G + E +DRN KAGSNVL +ESSERALLNRLM++L K+D DVLV
Sbjct: 618 SHFTVMRKLEGSIFPIGLSKESSDRNQKAGSNVLALESSERALLNRLMIELSKLDCDVLV 677
Query: 685 GHNISGFDLDVLLHRSQACRVPSSMWSKLGRLNRSTMPKLDRRGKTFGFGADPAIMSCVA 744
GHNISGFDLDVLLHR+Q C+VPS+MWSK+GRL RS MP+L + +G GA P IMSC+A
Sbjct: 678 GHNISGFDLDVLLHRAQTCKVPSNMWSKIGRLRRSVMPRLTKGNTLYGSGASPGIMSCIA 737
Query: 745 GRLLCDTYLCSRDLLKEVSYSLTHLAKTQLNQSRKEVAPHEVPKMFQTAKSLMELIEYGE 804
GRLLCDTYLCSRDLLKEVSYSLT LA+TQL + RKEV+PH++P MFQ++ +L++L+EYGE
Sbjct: 738 GRLLCDTYLCSRDLLKEVSYSLTQLAETQLKKERKEVSPHDIPPMFQSSGALLKLVEYGE 797
Query: 805 TDAWLSMELMFYLSVLPLTRQLTNLSGNLWGKTLQGARAQRVEYLLLHEFHKKKYIVPDK 864
TDA L++ELMF+LSVLPLTRQLTN+SGNLWGKTLQG+RAQRVEYLLLH FH +K+IVPDK
Sbjct: 798 TDACLALELMFHLSVLPLTRQLTNISGNLWGKTLQGSRAQRVEYLLLHAFHARKFIVPDK 857
Query: 865 FSNYAKETKLTKRRVTHGVDDGNFDDAD--INDANYHNDASESDHKKNKKAASYAGGLVL 922
F+ +KE TKR++ + D+AD I+D +H D K KK SYAGGLVL
Sbjct: 858 FAR-SKEFNSTKRKMNPDTEAARPDEADPSIDDEGHH-----VDQGKTKKGPSYAGGLVL 911
Query: 923 EPKKGLYDKYILLLDFNSLYPSIIQEYNICFTTVERSSDDSFPRLPSSKTTGVLPELLKK 982
EPKKGLYDKY+LLLDFNSLYPSIIQEYNICFTTV+RS+D + P LP+SKTTGVLPELLK
Sbjct: 912 EPKKGLYDKYVLLLDFNSLYPSIIQEYNICFTTVDRSADGNVPNLPASKTTGVLPELLKS 971
Query: 983 LVKLRREKKTWMKTASGLKRQQLDIEQQALKLTANSMYGCLGFSNSRFYAKPLAELITLQ 1042
LV+ RR K+W+KTASGLKRQQ DI+QQALKLTANSMYGCLGFSNSRFYAKPLAELITLQ
Sbjct: 972 LVERRRMVKSWLKTASGLKRQQFDIQQQALKLTANSMYGCLGFSNSRFYAKPLAELITLQ 1031
Query: 1043 GREILQSTVDLVQNNLNLEVIYGDTDSIMIYSGLDDIAKATSISKKVIQEVNKKYRCLEI 1102
GREILQ+TVDLVQNNLNLEVIYGDTDSIMI++GLDDI++A I+ KVIQEVNKKYRCLEI
Sbjct: 1032 GREILQNTVDLVQNNLNLEVIYGDTDSIMIHTGLDDISRAKGIAGKVIQEVNKKYRCLEI 1091
Query: 1103 DLDGLYKRMLLLKKKKYAAVKVQFKDGTPYEVIERKGLDIVRRDWSLLAKDLGDFCLTQI 1162
DLDG+YKRMLLLKKKKYAA+KV DG+ E IERKGLD+VRRDWSLL+K++GDFCL QI
Sbjct: 1092 DLDGIYKRMLLLKKKKYAAIKVAL-DGSLRENIERKGLDMVRRDWSLLSKEIGDFCLNQI 1150
Query: 1163 LSGGSCEDVVESIHNSLMKVQEEMRNGQVALEKYVITKTLTKPPEAYPDAKNQPHVLVAQ 1222
LSGGSC+DV+ESIH+SL++VQE+MR GQ LEKY+ITK+LTK PE YPDAKNQPH VA
Sbjct: 1151 LSGGSCDDVIESIHSSLVQVQEQMRGGQTELEKYIITKSLTKAPEDYPDAKNQPH--VAL 1208
Query: 1223 RLKQQGYTSGCSVGDTIPYVICCEQGGSSGSATGIALRARHPDELKQEQGTWLIDIDYYL 1282
RLKQ GY SGCS GDT+PY+IC +Q S + GIA RARHP+ELK+ W+IDIDYYL
Sbjct: 1209 RLKQNGY-SGCSAGDTVPYIICSQQDSESTHSGGIAQRARHPEELKRNPDKWMIDIDYYL 1267
Query: 1283 SQQIHPVISRLCASIQGTSPERLADCLGLDTSKFQHKSSEASDDPTSSLLFAGDDEESEK 1342
SQQIHPV+SRLCASIQGTSP RLA+CLGLD+SKFQ + +E+ + TSS+L + D+E E+
Sbjct: 1268 SQQIHPVVSRLCASIQGTSPARLAECLGLDSSKFQSRLTESDNQDTSSMLLSVIDDEDER 1327
Query: 1343 -----------PTSSGT------------------------DESDYNFWRKLCCPKC-FE 1366
P+ S T +++ NFWR++ CP+C +
Sbjct: 1328 YRGCEPLRLSCPSCSTTFDCPPVSSLIIGSSSGNVSNPNEGNDASINFWRRMRCPRCPDD 1387
Query: 1367 NGAGRISAAMIANQVKRQAEKFVLMYYRGLLMCDDETCKHTTRSVSFRLVGDSERGTVCP 1426
R+S A++ANQ+KRQA+ F+ +YY+GLLMCDDE CK++T SV+ R++GDSERGT+CP
Sbjct: 1388 TDESRVSPAVLANQMKRQADSFINLYYKGLLMCDDEGCKYSTHSVNLRVMGDSERGTICP 1447
Query: 1427 NYPRCNGHLNRKYTEADLYKQLSYFCHVFDTVCYIEKMEAKSRIPIEKELIKIRPIVDLA 1486
NYPRCNGHL R+YTEADLY+QLSYFC+V D +EK++ K+R+P EKE + ++LA
Sbjct: 1448 NYPRCNGHLVRQYTEADLYRQLSYFCYVVDATRCLEKLDQKARLPFEKEFAALSQTINLA 1507
Query: 1487 ASTIQKIRDRCAFGWVKLQDLVVA 1510
+QKIRDRCAFGWV+L+DL ++
Sbjct: 1508 LMEVQKIRDRCAFGWVQLKDLAIS 1531
Score = 67.0 bits (162), Expect = 5e-09
Identities = 33/64 (51%), Positives = 43/64 (66%)
Query: 4 DDGSSRKRRPTRGPDATARSQALELLRSRRSNGPRSTTTPQIRLENPIYDTIPEDEYTAL 63
D G+S +R RG +A ARS ALE LR+ R G R+ Q+R+E PIYDT+ E++Y AL
Sbjct: 7 DAGASGRRSRARGSEAVARSAALERLRAIRDGGARAAAAVQVRIEAPIYDTVAEEDYAAL 66
Query: 64 VASR 67
VA R
Sbjct: 67 VARR 70
>sp|O48653|DPOA_ORYSA DNA polymerase alpha catalytic subunit gi|2826900|dbj|BAA24573.1| DNA
polymerase alpha catalytic subunit [Oryza sativa]
Length = 1243
Score = 1468 bits (3801), Expect = 0.0
Identities = 746/1169 (63%), Positives = 915/1169 (77%), Gaps = 55/1169 (4%)
Query: 385 GTLYQSCCVVVKNMQRCVYAIPSHPLHSTNEMIQLEKDVQESRISPADFRKKLQDAVSDT 444
G + SCCVVVKNMQRC+YAIPS + + + +LEK+ S SP+ R L + S
Sbjct: 86 GKRFHSCCVVVKNMQRCIYAIPSSSIFPRDTISRLEKNSTTSDSSPS-LRASLHELASGL 144
Query: 445 KNEIAKHLVDLGVSSFSMAPVKRKYAFERTDIPAGENYVVKINYLFKDTALPVDLKGKSF 504
K+EIA L D VS+F+M PVKR YAFERTD+P GE YV+KINY +KD+ALP DL+G+ F
Sbjct: 145 KSEIADKLSDFNVSNFAMTPVKRNYAFERTDLPNGEQYVLKINYPYKDSALPTDLRGQHF 204
Query: 505 CALLGARNSALELFLIKRKIKGPSWLQVSNFSTCSASQRVSWCKFEVIVDSPKDIRASSP 564
ALLG NSALEL LIKRKIKGPSWL +S F C A+QRVSWCKFEV VDSPKDI
Sbjct: 205 HALLGTNNSALELLLIKRKIKGPSWLSISKFLACPATQRVSWCKFEVTVDSPKDISVLMT 264
Query: 565 SSSKITLVNPPVVVTAINLKTTINEKQNINEIVSASVVSCNMVKIDTPMLASEWKRPGML 624
S+ TL PPVVV A+NLKT INEK N++EIVSASV+ C+ VKID+PM + +W++ GML
Sbjct: 265 ST---TLEVPPVVVAAVNLKTIINEKHNVHEIVSASVICCHRVKIDSPMRSEDWQKRGML 321
Query: 625 THFTVIRKLDGNIFPMGFNTEVTDRNIKAGSNVLCVESSERALLNRLMLQLHKMDSDVLV 684
+HFTV+RKL+G+IFP+G + E +DRN KAGSNVL +ESSERALLNRLM++L K+D DVLV
Sbjct: 322 SHFTVMRKLEGSIFPIGLSKESSDRNQKAGSNVLALESSERALLNRLMIELSKLDCDVLV 381
Query: 685 GHNISGFDLDVLLHRSQACRVPSSMWSKLGRLNRSTMPKLDRRGKTFGFGADPAIMSCVA 744
GHNISGFDLDVLLHR+Q C+VPS+MWSK+GRL RS MP+L + +G GA P IMSC+A
Sbjct: 382 GHNISGFDLDVLLHRAQTCKVPSNMWSKIGRLRRSVMPRLTKGNTLYGSGASPGIMSCIA 441
Query: 745 GRLLCDTYLCSRDLLKEVSYSLTHLAKTQLNQSRKEVAPHEVPKMFQTAKSLMELIEYGE 804
GRLLCDTYLCSRDLLKEVSYSLT LA+TQL + RKEV+PH++P MFQ++ +L++L+EYGE
Sbjct: 442 GRLLCDTYLCSRDLLKEVSYSLTQLAETQLKKERKEVSPHDIPPMFQSSGALLKLVEYGE 501
Query: 805 TDAWLSMELMFYLSVLPLTRQLTNLSGNLWGKTLQGARAQRVEYLLLHEFHKKKYIVPDK 864
TDA L++ELMF+LSVLPLTRQLTN+SGNLWGKTLQG+RAQRVEYLLLH FH +K+IVPDK
Sbjct: 502 TDACLALELMFHLSVLPLTRQLTNISGNLWGKTLQGSRAQRVEYLLLHAFHARKFIVPDK 561
Query: 865 FSNYAKETKLTKRRVTHGVDDGNFDDAD--INDANYHNDASESDHKKNKKAASYAGGLVL 922
F+ +KE TKR++ + D+AD I+D +H D K KK SYAGGLVL
Sbjct: 562 FAR-SKEFNSTKRKMNPDTEAARPDEADPSIDDEGHH-----VDQGKTKKGPSYAGGLVL 615
Query: 923 EPKKGLYDKYILLLDFNSLYPSIIQEYNICFTTVERSSDDSFPRLPSSKTTGVLPELLKK 982
EPKKGLYDKY+LLLDFNSLYPSIIQEYNICFTTV+RS+D + P LP+SKTTGVLPELLK
Sbjct: 616 EPKKGLYDKYVLLLDFNSLYPSIIQEYNICFTTVDRSADGNVPNLPASKTTGVLPELLKS 675
Query: 983 LVKLRREKKTWMKTASGLKRQQLDIEQQALKLTANSMYGCLGFSNSRFYAKPLAELITLQ 1042
LV+ RR K+W+KTASGLKRQQ DI+QQALKLTANSMYGCLGFSNSRFYAKPLAELITLQ
Sbjct: 676 LVERRRMVKSWLKTASGLKRQQFDIQQQALKLTANSMYGCLGFSNSRFYAKPLAELITLQ 735
Query: 1043 GREILQSTVDLVQNNLNLEVIYGDTDSIMIYSGLDDIAKATSISKKVIQEVNKKYRCLEI 1102
GREILQ+TVDLVQNNLNLEVIYGDTDSIMI++GLDDI++A I+ KVIQEVNKKYRCLEI
Sbjct: 736 GREILQNTVDLVQNNLNLEVIYGDTDSIMIHTGLDDISRAKGIAGKVIQEVNKKYRCLEI 795
Query: 1103 DLDGLYKRMLLLKKKKYAAVKVQFKDGTPYEVIERKGLDIVRRDWSLLAKDLGDFCLTQI 1162
DLDG+YKRMLLLKKKKYAA+KV DG+ E IERKGLD+VRRDWSLL+K++GDFCL QI
Sbjct: 796 DLDGIYKRMLLLKKKKYAAIKVAL-DGSLRENIERKGLDMVRRDWSLLSKEIGDFCLNQI 854
Query: 1163 LSGGSCEDVVESIHNSLMKVQEEMRNGQVALEKYVITKTLTKPPEAYPDAKNQPHVLVAQ 1222
LSGGSC+DV+ESIH+SL++VQE+MR GQ LEKY+ITK+LTK PE YPDAKNQPHV VA
Sbjct: 855 LSGGSCDDVIESIHSSLVQVQEQMRGGQTELEKYIITKSLTKAPEDYPDAKNQPHVQVAL 914
Query: 1223 RLKQQGYTSGCSVGDTIPYVICCEQGGSSGSATGI-ALRARHPDELKQEQGTWL---IDI 1278
RLKQ GY SGCS GDT+PY+IC +Q S + I + RA+ E + T + I
Sbjct: 915 RLKQNGY-SGCSAGDTVPYIICSQQDSESTHSERIDSQRAQREPEGWKNLYTMVCLRILA 973
Query: 1279 DYYLSQQIHPVISRLCASI-QGTSPERLADCLGLDTSKFQHKSSEASDDPTSSLLFAGDD 1337
YYL Q+I+PV+SR+CA++ +GT P RLA+CLGLD+SKFQ + +E+ + TSS+L + D
Sbjct: 974 SYYLQQRINPVVSRVCAAVSRGTEPARLAECLGLDSSKFQSRLTESDNQDTSSMLLSVID 1033
Query: 1338 EESEK-----------PTSSGT------------------------DESDYNFWRKLCCP 1362
+E E+ P+ S T +++ NFWR++ CP
Sbjct: 1034 DEDERYRGCEPLRLSCPSCSTTFDCPPVSSLIIGSSSGNVSNPNEGNDASINFWRRMRCP 1093
Query: 1363 KC-FENGAGRISAAMIANQVKRQAEKFVLMYYRGLLMCDDETCKHTTRSVSFRLVGDSER 1421
+C + R+S A++ANQ+KRQA+ F+ +YY+GLLMCDDE CK++T SV+ R++GDSER
Sbjct: 1094 RCPDDTDESRVSPAVLANQMKRQADSFINLYYKGLLMCDDEGCKYSTHSVNLRVMGDSER 1153
Query: 1422 GTVCPNYPRCNGHLNRKYTEADLYKQLSYFCHVFDTVCYIEKMEAKSRIPIEKELIKIRP 1481
GT+CPNYPRCNGHL R+YTEADLY+QLSYFC+V D +EK++ K+R+P EKE +
Sbjct: 1154 GTICPNYPRCNGHLVRQYTEADLYRQLSYFCYVVDATRCLEKLDQKARLPFEKEFAALSQ 1213
Query: 1482 IVDLAASTIQKIRDRCAFGWVKLQDLVVA 1510
++LA +QKIRDRCAFGWV+L+DL ++
Sbjct: 1214 TINLALMEVQKIRDRCAFGWVQLKDLAIS 1242
>ref|NP_915661.1| putative DNA polymerase alpha catalytic subunit [Oryza sativa
(japonica cultivar-group)]
Length = 1637
Score = 1422 bits (3682), Expect = 0.0
Identities = 753/1280 (58%), Positives = 913/1280 (70%), Gaps = 179/1280 (13%)
Query: 385 GTLYQSCCVVVKNMQRCVYAIPSHPLHSTNEMIQLEKDVQESRISPADFRKKLQDAVSDT 444
G + SCCVVVKNMQRC+YAIPS + + + +LEK+ S SP+ R L + S
Sbjct: 382 GKRFHSCCVVVKNMQRCIYAIPSSSIFPRDTISRLEKNSTTSDSSPS-LRASLHELASGL 440
Query: 445 KNEIAKHLVDLGVSSFSMAPVKRKYAFERTDIPAGENYVVKINYLFKDTALPVDLKGKSF 504
K+EIA L D VS+F+M PVKR YAFERTD+P GE YV+KINY +KD ALP DL+G+ F
Sbjct: 441 KSEIADKLSDFNVSNFAMTPVKRNYAFERTDLPNGEQYVLKINYPYKDPALPTDLRGQHF 500
Query: 505 CALLGARNSALELFLIKRKIKGPSWLQVSNFSTCSASQRVSWCKFEVIVDSPKDIRASSP 564
ALLG NSALEL LIKRKIKGPSWL +S F C A+QRVSWCKFEV VDSPKDI
Sbjct: 501 HALLGTNNSALELLLIKRKIKGPSWLSISKFLACPATQRVSWCKFEVTVDSPKDISVLMT 560
Query: 565 SSSKITLVNPPVVVTAINLKTTINEKQNINEIVSASVVSCNMVKIDTPMLASEWKRPGML 624
S+ TL PPVVV A+NLKT INEK N++EIVSASV+ C+ VKID+PM + +W++ GML
Sbjct: 561 ST---TLEVPPVVVAAVNLKTIINEKHNVHEIVSASVICCHRVKIDSPMRSEDWQKRGML 617
Query: 625 THFTVIRKLDGNIFPMGFNTEVTDRNIKAGSNVLCVESSERALLNRLMLQLHKMDSDVLV 684
+HFTV+RKL+G+IFP+G + E +DRN KAGSNVL +ESSERALLNRLM++L K+D DVLV
Sbjct: 618 SHFTVMRKLEGSIFPIGLSKESSDRNQKAGSNVLALESSERALLNRLMIELSKLDCDVLV 677
Query: 685 GHNISGFDLDVLLHRSQACRVPSSMWSKLGRLNRSTMPKLDRRGKTFGFGADPAIMSCVA 744
GHNISGFDLDVLLHR+Q C+VPS+MWSK+GRL RS MP+L + +G GA P IMSC+A
Sbjct: 678 GHNISGFDLDVLLHRAQTCKVPSNMWSKIGRLRRSVMPRLTKGNTLYGSGASPGIMSCIA 737
Query: 745 GRLLCDTYLCSRDLLKEVSYSLTHLAKTQLNQSRKEVAPHEVPKMFQTAKSLMELIEYGE 804
GRLLCDTYLCSRDLLKEVSYSLT LA+TQL + RKEV+PH++P MFQ++ +L++L+EYGE
Sbjct: 738 GRLLCDTYLCSRDLLKEVSYSLTQLAETQLKKERKEVSPHDIPPMFQSSGALLKLVEYGE 797
Query: 805 TDAWLSMELMFYLSVLPLTRQLTNLSGNLWGKTLQGARAQRVEYLLLHEFHKKKYIVPDK 864
TDA L++ELMF+LSVLPLTRQLTN+SGNLWGKTLQG+RAQRVEYLLLH FH +K+IVPDK
Sbjct: 798 TDACLALELMFHLSVLPLTRQLTNISGNLWGKTLQGSRAQRVEYLLLHAFHARKFIVPDK 857
Query: 865 FSNYAKETKLTKRRVTHGVDDGNFDDAD--INDANYHNDASESDHKKNKKAASYAGGLVL 922
F+ +KE TKR++ + D+AD I+D +H D K KK SYAGGLVL
Sbjct: 858 FAR-SKEFNSTKRKMNPDTEAARPDEADPSIDDEGHHVDQG-----KTKKGPSYAGGLVL 911
Query: 923 EPKKGLYDKYILLLDFNSLYPSIIQEYNICFTTVERSSDDSFPRLPSSKTTGVLPE---- 978
EPKKGLYDKY+LLLDFNSLYPSIIQEYNICFTTV+RS+D + P LP+SKTTGVLPE
Sbjct: 912 EPKKGLYDKYVLLLDFNSLYPSIIQEYNICFTTVDRSADGNVPNLPASKTTGVLPESFNN 971
Query: 979 ------------------------------------LLKKLVKLRREKKTWMKTASGLKR 1002
LLK LV+ RR K+W+KTASGLKR
Sbjct: 972 LVLHGFLTAMRNLGFGLDCGDMISVGLLMRGFLMIKLLKSLVERRRMVKSWLKTASGLKR 1031
Query: 1003 QQLDIEQQALKLTANSMYGCLGFSNSRFYAKPLAELITLQGREILQSTVDLVQNNLNLEV 1062
QQ DI+QQALKLTAN RFYAKPLAELITLQGREILQ+TVDLVQNNLNLEV
Sbjct: 1032 QQFDIQQQALKLTAN-----------RFYAKPLAELITLQGREILQNTVDLVQNNLNLEV 1080
Query: 1063 IYGDTDSIMIYSGLDDIAKATSISKKVIQE------------------VNKKYRCL---- 1100
IYGDTDSIMI++GLDDI++A I+ KVIQE VNKKYRCL
Sbjct: 1081 IYGDTDSIMIHTGLDDISRAKGIAGKVIQERDSMHSGERPVNISALMQVNKKYRCLEIDL 1140
Query: 1101 ------------------------------------------------------EIDLDG 1106
EIDLDG
Sbjct: 1141 DGIYKRMLLLKKKKYAAIKVALDGSLRERDSMHSGERPVNISALMQVNKKYRCLEIDLDG 1200
Query: 1107 LYKRMLLLKKKKYAAVKVQFKDGTPYEV-------------------------IERKGLD 1141
+YKRMLLLKKKKYAA+KV DG+ EV IERKGLD
Sbjct: 1201 IYKRMLLLKKKKYAAIKVAL-DGSLREVCGCSDFQNYILSSKTGIIKECLMQNIERKGLD 1259
Query: 1142 IVRRDWSLLAKDLGDFCLTQILSGGSCEDVVESIHNSLMKVQEEMRNGQVALEKYVITKT 1201
+VRRDWSLL+K++GDFCL QILSGGSC+DV+ESIH+SL++VQE+MR GQ LEKY+ITK+
Sbjct: 1260 MVRRDWSLLSKEIGDFCLNQILSGGSCDDVIESIHSSLVQVQEQMRGGQTELEKYIITKS 1319
Query: 1202 LTKPPEAYPDAKNQPHVLVAQRLKQQGYTSGCSVGDTIPYVICCEQGGSSGSATGIALRA 1261
LTK PE YPDAKNQPH VA RLKQ GY SGCS GDT+PY+IC +Q S + GIA RA
Sbjct: 1320 LTKAPEDYPDAKNQPH--VALRLKQNGY-SGCSAGDTVPYIICSQQDSESTHSGGIAQRA 1376
Query: 1262 RHPDELKQEQGTWLIDIDYYLSQQIHPVISRLCASIQGTSPERLADCLGLDTSKFQHKSS 1321
RHP+ELK+ W+IDIDYYLSQQIHPV+SRLCASIQGTSP RLA+CLGLD+SKFQ + +
Sbjct: 1377 RHPEELKRNPDKWMIDIDYYLSQQIHPVVSRLCASIQGTSPARLAECLGLDSSKFQSRLT 1436
Query: 1322 EASDDPTSSLLFAGDDEESEK---PTSSGT-------DESDYNFWRKLCCPKC-FENGAG 1370
E+ + TSS+L + D+E E +SSG +++ NFWR++ CP+C +
Sbjct: 1437 ESDNQDTSSMLLSVIDDEDESLIIGSSSGNVSNPNEGNDASINFWRRMRCPRCPDDTDES 1496
Query: 1371 RISAAMIANQVKRQAEKFVLMYYRGLLMCDDETCKHTTRSVSFRLVGDSERGTVCPNYPR 1430
R+S A++ANQ+KRQA+ F+ +YY+GLLMCDDE CK++T SV+ R++GDSERGT+CPNYPR
Sbjct: 1497 RVSPAVLANQMKRQADSFINLYYKGLLMCDDEGCKYSTHSVNLRVMGDSERGTICPNYPR 1556
Query: 1431 CNGHLNRKYTEADLYKQLSYFCHVFDTVCYIEKMEAKSRIPIEKELIKIRPIVDLAASTI 1490
CNGHL R+YTEADLY+QLSYFC+V D +EK++ K+R+P EKE + ++LA +
Sbjct: 1557 CNGHLVRQYTEADLYRQLSYFCYVVDATRCLEKLDQKARLPFEKEFAALSQTINLALMEV 1616
Query: 1491 QKIRDRCAFGWVKLQDLVVA 1510
QKIRDRCAFGWV+L+DL ++
Sbjct: 1617 QKIRDRCAFGWVQLKDLAIS 1636
Score = 67.0 bits (162), Expect = 5e-09
Identities = 33/64 (51%), Positives = 43/64 (66%)
Query: 4 DDGSSRKRRPTRGPDATARSQALELLRSRRSNGPRSTTTPQIRLENPIYDTIPEDEYTAL 63
D G+S +R RG +A ARS ALE LR+ R G R+ Q+R+E PIYDT+ E++Y AL
Sbjct: 7 DAGASGRRSRARGSEAVARSAALERLRAIRDGGARAAAAVQVRIEAPIYDTVAEEDYAAL 66
Query: 64 VASR 67
VA R
Sbjct: 67 VARR 70
>dbj|BAD92011.1| DNA polymerase alpha catalytic subunit [Gallus gallus]
Length = 1462
Score = 695 bits (1793), Expect = 0.0
Identities = 450/1165 (38%), Positives = 647/1165 (54%), Gaps = 137/1165 (11%)
Query: 382 VW--QGTLYQSCCVVVKNMQRCVYAIPSHPLHSTNEMIQLEKDVQESRISPADFRKKLQD 439
VW Y SCCV VKN++R VY +P EM E+ ++ + K+ D
Sbjct: 355 VWIESANTYVSCCVTVKNIERTVYLLPRE-----TEMDLSSGKETETPVTIMNVFKEFND 409
Query: 440 AVSDTKNEIAKHLVDLGVSSFSMAPVKRKYAFERTDIPAGENYVVKINYLFKDTALPVDL 499
+S K +I K F V++ YAFE D+PA Y +++ Y + LP DL
Sbjct: 410 CIS-PKYKIMK---------FKSKKVEKYYAFEIPDVPAKSEY-LEVKYSAEYPRLPQDL 458
Query: 500 KGKSFCALLGARNSALELFLIKRKIKGPSWLQVSNFSTCSASQRVSWCKFEVIVDSPKDI 559
KG++F + G S+LEL L+ RKIKGP WL++ N ++Q VSWCK E + P +
Sbjct: 459 KGETFSHVFGTNTSSLELLLMSRKIKGPCWLEIKN--PQPSNQSVSWCKVEAVAMKPGLV 516
Query: 560 RASSPSSSKITLVNPPVVVTAINLKTTINEKQNINEIVSASVVSCNMVKIDTPMLASEWK 619
K L PP+VV + ++KT N K + NEIV+ + + +D
Sbjct: 517 NV-----VKDLLPPPPLVVMSFSMKTIQNPKTHQNEIVAMAALIHQKFPLDKAP-----P 566
Query: 620 RPGMLTHFTVIRKLDGNIFPMGFNTEVTDRNIKAGSNVLCVESSERALLNRLMLQLHKMD 679
+P THF + K + IFP F E+ +N K + + ++ER LL + ++HK+D
Sbjct: 567 QPPFQTHFCAVSKPNDCIFPYDFKEEIKKKNAK-----IEIAATERTLLGFFLAKIHKID 621
Query: 680 SDVLVGHNISGFDLDVLLHRSQACRVPSSMWSKLGRLNRSTMPKLDRRGKTFGFGADPAI 739
DV+VGHNI GFDL+VLL R C+VP WSK+GRL RS MPKL RG GFG
Sbjct: 622 PDVVVGHNIYGFDLEVLLQRINVCKVPH--WSKIGRLRRSNMPKLGGRG---GFGE---- 672
Query: 740 MSCVAGRLLCDTYLCSRDLLKEVSYSLTHLAKTQLNQSRKEVAPHEVPKMFQTAKSLMEL 799
+ GR++CD + +++L++ SY L+ L L R + P E+ ++ + L+ +
Sbjct: 673 RNAACGRMICDVEISAKELIRCKSYHLSELVHQILKTERVTILPEEIRNLYSDSPHLLFM 732
Query: 800 IEYGETDAWLSMELMFYLSVLPLTRQLTNLSGNLWGKTLQGARAQRVEYLLLHEFHKKKY 859
+E TDA +++M L+VLPL Q+TN+SGN+ +T+ G R++R E+LLLH F++K Y
Sbjct: 733 LENTWTDAKFILQIMCELNVLPLALQITNISGNVMSRTMMGGRSERNEFLLLHAFYEKDY 792
Query: 860 IVPDKFSNYAKETKLTKRRVTHGVDDGNFDDADINDANYHNDASESDHKKNKKAASYAGG 919
IVPDK ++ K+ + VD +D D D N K KK A+YAGG
Sbjct: 793 IVPDK--------QVFKKPLQKLVD----EDEDFEDQN--------KSKIGKKKAAYAGG 832
Query: 920 LVLEPKKGLYDKYILLLDFNSLYPSIIQEYNICFTTVERSS-----------DDSFPRLP 968
LVL+PK G YDK+ILLLDFNSLYPSIIQE+NICFTTV+R S ++ P LP
Sbjct: 833 LVLDPKVGFYDKFILLLDFNSLYPSIIQEFNICFTTVQRLSSEAQKRAEVEEEEEIPELP 892
Query: 969 S-SKTTGVLPELLKKLVKLRREKKTWMK--TASGLKRQQLDIEQQALKLTANSMYGCLGF 1025
S G+LP+ ++KLV+ RR+ K MK + Q DI Q+ALKLTANSMYGCLGF
Sbjct: 893 DPSLEMGILPKEIRKLVERRRQVKQLMKQPDLNPDLYLQYDIRQKALKLTANSMYGCLGF 952
Query: 1026 SNSRFYAKPLAELITLQGREILQSTVDLVQNNLNLEVIYGDTDSIMIYSGLDDIAKATSI 1085
S SRFYAKPLA L+T +GREIL T ++VQ +NLEVIYGDTDSIMI + ++ + +
Sbjct: 953 SYSRFYAKPLAALVTHKGREILMHTKEMVQ-KMNLEVIYGDTDSIMINTNSTNLDEVFKL 1011
Query: 1086 SKKVIQEVNKKYRCLEIDLDGLYKRMLLLKKKKYAAVKVQ-FKDGTPYEVIERKGLDIVR 1144
K+ EVNK Y+ LEID+DG++K +LLLKKKKYAA+ V+ DG E KGLDIVR
Sbjct: 1012 GNKIKSEVNKLYKLLEIDIDGVFKSLLLLKKKKYAALTVEPTGDGKYVTKQELKGLDIVR 1071
Query: 1145 RDWSLLAKDLGDFCLTQILSGGSCEDVVESIHNSLMKVQEEMRNGQVALEKYVITKTLTK 1204
RDW LAK+ G++ + QILS + +VE+I L+++ E + NGQ+ + ++ I K LTK
Sbjct: 1072 RDWCDLAKETGNYVIGQILSDQPRDIIVENIQRRLIEIGENVINGQIPVNQFEINKALTK 1131
Query: 1205 PPEAYPDAKNQPHVLVAQRLKQQGYTSGCSVGDTIPYVICCEQGGSSGSATGIALRARHP 1264
P+ YPD K+ PHV VA + QG GDT+ Y+IC Q GS+ SA + RA P
Sbjct: 1132 DPQDYPDKKSLPHVHVAMWINSQGGRK-VKAGDTVSYIIC--QDGSNLSA---SQRAYAP 1185
Query: 1265 DELKQEQGTWLIDIDYYLSQQIHPVISRLCASIQGTSPERLADCLGLDTSKFQHKSSEAS 1324
++L Q+Q ID YYLSQQIHPV++R+C I+G +A LGLD S+F+
Sbjct: 1186 EQL-QKQDNLTIDTQYYLSQQIHPVVARICEPIEGIDSVLIATWLGLDPSQFRVHHHYHK 1244
Query: 1325 DDPTSSLLFAGDDEESEKPTSSGTDESDYNFWR--KLCCPKC-----FEN---GAGRISA 1374
D+ +L+ + TDE Y K CC KC ++N +GR
Sbjct: 1245 DEENDALVGG---------PAQLTDEEKYRDCERFKFCCLKCGTENIYDNVFDCSGRFIE 1295
Query: 1375 AMIANQVKRQAE-------------------KFVLMYYRGLLMCDDETCKHTTRSVSFRL 1415
+ K + E +++ YY G L+C+D TC++ TR +
Sbjct: 1296 PSLQRCSKSECEEPPFNHVVQMNNKLLLDIRRYLKKYYNGWLICEDPTCQNRTRRLPLSF 1355
Query: 1416 VGDSERGTVCPNYPRCNGHLNRKYTEADLYKQLSYFCHVFDTVCYIEKMEAKSRIPIEKE 1475
S G +C + L +Y++ LY QL ++ ++FD ++K+ + ++E
Sbjct: 1356 ---SRSGPICQACRK--AILRPEYSDKALYTQLCFYRYIFDVEYAMDKVITEE----DRE 1406
Query: 1476 LIKIRPIVDLAASTIQKIR---DRC 1497
++ +P+ + +K++ D+C
Sbjct: 1407 FVRRKPLRKEVSEAYRKLKSTVDKC 1431
>dbj|BAD92010.1| DNA polymerase alpha catalytic subunit [Caiman crocodilus]
Length = 1419
Score = 694 bits (1791), Expect = 0.0
Identities = 454/1168 (38%), Positives = 646/1168 (54%), Gaps = 134/1168 (11%)
Query: 388 YQSCCVVVKNMQRCVYAIPSHPLHSTNEMIQLEKDVQESRISPADFRKKLQDAVSDTKNE 447
Y SCCV VKN++R VY +P E+ E+ ++ K+ D +S
Sbjct: 320 YVSCCVTVKNIERTVYLLPRKM-----EVNLSSGQETENPVTIMSVYKEFNDQIS----- 369
Query: 448 IAKHLVDLGVSSFSMAPVKRKYAFERTDIPAGENYVVKINYLFKDTALPVDLKGKSFCAL 507
V + F V++ YAFE D+PA +Y+ ++ Y + + LP DLKG++F +
Sbjct: 370 -----VKYKIMKFKSKKVEKHYAFEIPDVPAKSDYL-EVRYSAEFSRLPQDLKGETFSHV 423
Query: 508 LGARNSALELFLIKRKIKGPSWLQVSNFSTCSASQRVSWCKFEVIVDSPKDIRASSPSSS 567
G +S+LEL L+ RKIKGP WL++ N +SQ VSWCK E + P +
Sbjct: 424 FGTNSSSLELLLMSRKIKGPCWLEIKNPQP--SSQSVSWCKMEAVALKPDLVNVIKD--- 478
Query: 568 KITLVNPPVVVTAINLKTTINEKQNINEIVS-ASVVSCNMVKIDTPMLASEWKRPGMLTH 626
L PP+VV +++++T N K + NE+++ A++V N P +P TH
Sbjct: 479 ---LPPPPLVVISLSIRTIPNPKTHQNEVMAIAALVHQNFCLDKAP------PQPPFQTH 529
Query: 627 FTVIRKLDGNIFPMGFNTEVTDRNIKAGSNVLCVESSERALLNRLMLQLHKMDSDVLVGH 686
F VI K + IFP F + +N K + + ++ER LL + ++HK+D DV+VGH
Sbjct: 530 FCVISKPNDCIFPYDFKDVIKTKNAK-----IEIAATERTLLGFFLAKIHKIDPDVVVGH 584
Query: 687 NISGFDLDVLLHRSQACRVPSSMWSKLGRLNRSTMPKLDRRGKTFGFGADPAIMSCVAGR 746
NI GFDL+VLL R AC+VP WSK+GRL RS MPKL RG GF A + GR
Sbjct: 585 NIYGFDLEVLLQRINACKVPH--WSKIGRLRRSNMPKLGGRG---GF----AERNAACGR 635
Query: 747 LLCDTYLCSRDLLKEVSYSLTHLAKTQLNQSRKEVAPHEVPKMFQTAKSLMELIEYGETD 806
++CD + +++L++ SY L+ L L R + P E+ KMF + LM ++E TD
Sbjct: 636 MICDVEISAKELIRCKSYHLSELVHQILKTERITIPPEEIRKMFSNSSHLMCMLENSWTD 695
Query: 807 AWLSMELMFYLSVLPLTRQLTNLSGNLWGKTLQGARAQRVEYLLLHEFHKKKYIVPDKFS 866
A +++M L+VLPL Q+TN+SGN+ +T+ G R++R EYLLLH F+++ YIVPDK
Sbjct: 696 AKFILQIMCELNVLPLALQITNISGNIMSRTMMGGRSERNEYLLLHAFYERDYIVPDKQV 755
Query: 867 NYAKETKLTKRRVTHGVDDGNFDDADINDANYHNDASESDHKKNKKAASYAGGLVLEPKK 926
+ KL +D +F+D ++ K +K A+YAGGLVL+PK
Sbjct: 756 FKKPQQKLVD-------EDEDFED-------------QTKSKIGRKKAAYAGGLVLDPKV 795
Query: 927 GLYDKYILLLDFNSLYPSIIQEYNICFTTVERSSDD-----------SFPRLP-SSKTTG 974
G YDK+ILLLDFNSLYPSIIQE+NICFTTV+R S D P LP SS G
Sbjct: 796 GFYDKFILLLDFNSLYPSIIQEFNICFTTVQRVSSDVQKRTEEGEEEEIPELPDSSLEMG 855
Query: 975 VLPELLKKLVKLRREKKTWMKT--ASGLKRQQLDIEQQALKLTANSMYGCLGFSNSRFYA 1032
+LP+ ++KLV+ RR+ K MK + Q DI Q+ALKLTANSMYGCLGFS SRFYA
Sbjct: 856 ILPKEIRKLVERRRQVKQLMKQPHLNPDLYLQYDIRQKALKLTANSMYGCLGFSYSRFYA 915
Query: 1033 KPLAELITLQGREILQSTVDLVQNNLNLEVIYGDTDSIMIYSGLDDIAKATSISKKVIQE 1092
KPLA L+T +GREIL T ++VQ +NLEVIYGDTDSIMI + ++ + + K+ E
Sbjct: 916 KPLAALVTHKGREILMHTKEMVQ-KMNLEVIYGDTDSIMINTNSTNLEEVLKLGNKIKSE 974
Query: 1093 VNKKYRCLEIDLDGLYKRMLLLKKKKYAAVKVQ-FKDGTPYEVIERKGLDIVRRDWSLLA 1151
VN+ Y+ LEID+DG++K +LLLKKKKYAA+ V+ DG E KGLDIVRRDW LA
Sbjct: 975 VNRLYKLLEIDIDGIFKSLLLLKKKKYAALTVEPTGDGNYVTKQELKGLDIVRRDWCDLA 1034
Query: 1152 KDLGDFCLTQILSGGSCEDVVESIHNSLMKVQEEMRNGQVALEKYVITKTLTKPPEAYPD 1211
K+ G++ + QILS + + +VE+I L+ + E + NG V + ++ I K LTK P+ YPD
Sbjct: 1035 KESGNYVIGQILSDQTRDIIVENIQRRLIDIGENVTNGTVPISQFEINKALTKDPQDYPD 1094
Query: 1212 AKNQPHVLVAQRLKQQGYTSGCSVGDTIPYVICCEQGGSSGSATGIALRARHPDELKQEQ 1271
K+ PHV VA + QG S GDT+ YVIC Q GS+ SA + RA P++L Q+Q
Sbjct: 1095 KKSLPHVHVAMWINSQGGRKVKS-GDTVSYVIC--QDGSNLSA---SQRAYAPEQL-QKQ 1147
Query: 1272 GTWLIDIDYYLSQQIHPVISRLCASIQGTSPERLADCLGLDTSKFQHKSSEASDDPTSSL 1331
ID YYLSQQIHPV++R+C I G +A LGLD S+F+ D+ +
Sbjct: 1148 ENLTIDTQYYLSQQIHPVVARICEPIDGIDSVLIATWLGLDPSQFKVHHHYHKDEENDAF 1207
Query: 1332 LFAGDDEESEKPTSSGTDESDYNFWR--KLCCPKC-FEN-------GAGRISAAMIANQV 1381
L + TDE Y K CPKC EN G+G+ +
Sbjct: 1208 LGG---------LAQFTDEEKYRDCERFKFPCPKCGTENIYDSVFDGSGQFLEPSLQQCS 1258
Query: 1382 KRQAEK-------------------FVLMYYRGLLMCDDETCKHTTRSVSFRLVGDSERG 1422
K++ + ++ YY G L+C+D C++ TR + S G
Sbjct: 1259 KKECNELPFCHVTQMNNKLLFDIRCYLKKYYNGWLICEDPACQNRTRRLPLSF---SRNG 1315
Query: 1423 TVCPNYPRCNGHLNRKYTEADLYKQLSYFCHVFDTVCYIEK-MEAKSRIPIEKELI--KI 1479
+C + L +Y++ LY QL ++ ++FD ++K + + ++ EK L KI
Sbjct: 1316 PLCQACRK--AVLRPEYSDKALYNQLCFYRYIFDVEYAMDKVITEEEKVWAEKNLALKKI 1373
Query: 1480 RPIVDLAASTIQKIRDRCAFGWVKLQDL 1507
+ + +T+ ++ V L L
Sbjct: 1374 KEVYKKLKNTVDTCLSMSSYSEVNLGKL 1401
>gb|AAG35630.1| DNA polymerase alpha [Xenopus laevis]
gi|45476976|sp|Q9DE46|DPOA_XENLA DNA polymerase alpha
catalytic subunit
Length = 1458
Score = 692 bits (1785), Expect = 0.0
Identities = 455/1166 (39%), Positives = 631/1166 (54%), Gaps = 134/1166 (11%)
Query: 388 YQSCCVVVKNMQRCVYAIPSHPLHSTNEMIQLEKDVQESRISPADFRKKLQDAVSDTKNE 447
Y SCCV VKN++R VY +P + KD + +S ++ +AV++ K +
Sbjct: 373 YVSCCVSVKNIERTVYLLP----RENRVQLSTGKDTG-APVSMMHVYQEFNEAVAE-KYK 426
Query: 448 IAKHLVDLGVSSFSMAPVKRKYAFERTDIPAGENYVVKINYLFKDTALPVDLKGKSFCAL 507
I K F V + YAFE D+PA Y+ ++ Y LP DLKG++F +
Sbjct: 427 IMK---------FKSKKVDKDYAFEIPDVPASSEYL-EVRYSADSPQLPQDLKGETFSHV 476
Query: 508 LGARNSALELFLIKRKIKGPSWLQVSNFSTCSASQRVSWCKFEVIVDSPKDIRASSPSSS 567
G S+LELFL+ RKIKGPSWL++ S +SQ +SWCK E +V P +
Sbjct: 477 FGTNTSSLELFLLSRKIKGPSWLEIK--SPQLSSQPMSWCKVEAVVTRPDQVSVVKD--- 531
Query: 568 KITLVNPPVVVTAINLKTTINEKQNINEIVSASVVSCNMVKIDTPMLASEWKRPGMLTHF 627
L PPVVV ++++KT N K + NEIV+ + + + +D +P THF
Sbjct: 532 ---LAPPPVVVLSLSMKTVQNAKTHQNEIVAIAALVHHTFPLDKAP-----PQPPFQTHF 583
Query: 628 TVIRKLDGNIFPMGFNTEVTDRNIKAGSNVLCVESSERALLNRLMLQLHKMDSDVLVGHN 687
V+ KL+ IFP +N V +N + + +ER LL + ++HK+D DV+VGH+
Sbjct: 584 CVLSKLNDCIFPYDYNEAVKQKNAN-----IEIALTERTLLGFFLAKIHKIDPDVIVGHD 638
Query: 688 ISGFDLDVLLHRSQACRVPSSMWSKLGRLNRSTMPKLDRRGKTFGFGADPAIMSCVAGRL 747
I GFDL+VLL R +C+VP WSK+GRL RS MPKL R GF A + GR+
Sbjct: 639 IYGFDLEVLLQRINSCKVP--FWSKIGRLRRSVMPKLGGRS---GF----AERNAACGRI 689
Query: 748 LCDTYLCSRDLLKEVSYSLTHLAKTQLNQSRKEVAPHEVPKMFQTAKSLMELIEYGETDA 807
+CD + +++L++ SY L+ L L R + P + + + L+ ++E DA
Sbjct: 690 ICDIEISAKELIRCKSYHLSELVHQILKAERVVIPPENIRNAYNDSVHLLYMLENTWIDA 749
Query: 808 WLSMELMFYLSVLPLTRQLTNLSGNLWGKTLQGARAQRVEYLLLHEFHKKKYIVPDKFSN 867
+++M L+VLPL Q+TN++GN+ +TL G R++R EYLLLH F + +IVPDK
Sbjct: 750 KFILQIMCELNVLPLALQITNIAGNVMSRTLMGGRSERNEYLLLHAFTENNFIVPDK--- 806
Query: 868 YAKETKLTKRRVTHGVDDGNFDDADINDANYHNDASESDHKKNK--KAASYAGGLVLEPK 925
+ K+ V+D ND +D KNK K A+YAGGLVLEPK
Sbjct: 807 -----PVFKKMQQTTVED--------------NDDMGTDQNKNKSRKKAAYAGGLVLEPK 847
Query: 926 KGLYDKYILLLDFNSLYPSIIQEYNICFTTVERSS--------DDSFPRLPSSKTT-GVL 976
G YDK+ILLLDFNSLYPSIIQEYNICFTTV R + D P LP S G+L
Sbjct: 848 VGFYDKFILLLDFNSLYPSIIQEYNICFTTVHREAPSTQKGEDQDEIPELPHSDLEMGIL 907
Query: 977 PELLKKLVKLRREKKTWMKTASGLKRQ---QLDIEQQALKLTANSMYGCLGFSNSRFYAK 1033
P ++KLV+ RR K MK L Q DI Q+ALKLTANSMYGCLGFS SRFYAK
Sbjct: 908 PREIRKLVERRRHVKQLMKQPD-LNPDLYLQYDIRQKALKLTANSMYGCLGFSYSRFYAK 966
Query: 1034 PLAELITLQGREILQSTVDLVQNNLNLEVIYGDTDSIMIYSGLDDIAKATSISKKVIQEV 1093
PLA L+T QGREIL T ++VQ +NLEVIYGDTDSIMI + +++ + + +V E+
Sbjct: 967 PLAALVTHQGREILLHTKEMVQK-MNLEVIYGDTDSIMINTNCNNLEEVFKLGNRVKSEI 1025
Query: 1094 NKKYRCLEIDLDGLYKRMLLLKKKKYAAVKVQ-FKDGTPYEVIERKGLDIVRRDWSLLAK 1152
NK Y+ LEID+DG++K +LLLKKKKYAA+ V+ DG E KGLDIVRRDW LAK
Sbjct: 1026 NKSYKLLEIDIDGIFKSLLLLKKKKYAALTVEPTGDGKYVTKQELKGLDIVRRDWCELAK 1085
Query: 1153 DLGDFCLTQILSGGSCEDVVESIHNSLMKVQEEMRNGQVALEKYVITKTLTKPPEAYPDA 1212
G++ ++QILS + +VE+I L ++ E + NG V + +Y I K LTK P+ YPD
Sbjct: 1086 QAGNYVISQILSDQPRDSIVENIQKKLTEIGENVTNGTVPITQYEINKALTKDPQDYPDK 1145
Query: 1213 KNQPHVLVAQRLKQQGYTSGCSVGDTIPYVICCEQGGSSGSATGIALRARHPDELKQEQG 1272
K+ PHV VA + QG GDTI YVIC Q GS+ SA+ + + E Q+Q
Sbjct: 1146 KSLPHVHVALWINSQGGRK-VKAGDTISYVIC--QDGSNLSAS----QRAYAQEQLQKQE 1198
Query: 1273 TWLIDIDYYLSQQIHPVISRLCASIQGTSPERLADCLGLDTSKFQHKSSEASDDPTSSLL 1332
ID YYLSQQ+HPV++R+C I G +A LGLD S+F+ D+ +LL
Sbjct: 1199 NLSIDTQYYLSQQVHPVVARICEPIDGIDSALIAMWLGLDPSQFRAHRHYQQDEENDALL 1258
Query: 1333 FAGDDEESEKPTSSGTDESDYNFWR--KLCCPKC----------------FENGAGRIS- 1373
S TDE Y K CPKC E G R S
Sbjct: 1259 GG---------PSQLTDEEKYRDCERFKFFCPKCGTENIYDNVFDGSGLQIEPGLKRCSK 1309
Query: 1374 ----------AAMIANQVKRQAEKFVLMYYRGLLMCDDETCKHTTRSVSFRLVGDSERGT 1423
+ N++ +++ YY G L+C+++TC++ TR + S G
Sbjct: 1310 PECDASPLDYVIQVHNKLLLDIRRYIKKYYSGWLVCEEKTCQNRTRRLPLSF---SRNGP 1366
Query: 1424 VCPNYPRCNGHLNRKYTEADLYKQLSYFCHVFDTVCYIEK-MEAKSRIPIEKELI-KIRP 1481
+C + L +Y E LY QL ++ +FD +EK + + R ++K+L +
Sbjct: 1367 ICQACSKAT--LRSEYPEKALYTQLCFYRFIFDWDYALEKVVSEQERGHLKKKLFQESEN 1424
Query: 1482 IVDLAASTIQKIRDRCAFGWVKLQDL 1507
ST+ ++ R + V L L
Sbjct: 1425 QYKKLKSTVDQVLSRSGYSEVNLSKL 1450
>gb|EAK85452.1| hypothetical protein UM04529.1 [Ustilago maydis 521]
gi|49076304|ref|XP_402144.1| hypothetical protein
UM04529.1 [Ustilago maydis 521]
Length = 1667
Score = 686 bits (1769), Expect = 0.0
Identities = 450/1183 (38%), Positives = 620/1183 (52%), Gaps = 174/1183 (14%)
Query: 388 YQSCCVVVKNMQRCVYAIPSHPLHSTNEMIQLEKDVQESRISPADFRKKLQDAVSDTKNE 447
Y SCC+ V ++RC++ +P QLE + R P +D + D E
Sbjct: 501 YVSCCLTVNGIERCIFLLPRSK--------QLENGHETDR--PVG-----EDEIYDEFEE 545
Query: 448 I-AKHLVDLGVSSFSMAPVKRKYAFERTDIPAGENYVVKINYLFKDTALPVDLKGKSFCA 506
+ AKH G+ F V RKYAFE+ +PA NY+ KI Y F + LP D KGK+F
Sbjct: 546 LSAKH----GIKGFLSKWVTRKYAFEQAGVPAESNYM-KIRYGFDEPQLPFDFKGKTFSK 600
Query: 507 LLGARNSALELFLIKRKIKGPSWLQVSNFSTCSASQRVSWCKFEVIVDSPKDIRASSPSS 566
G S EL ++KR+I GPSWL++SN S S +SWCK EV +D PKDI S +
Sbjct: 601 AFGTNTSPFELLVVKRRIFGPSWLKISNASLAEGSTPISWCKMEVSIDDPKDISPISDAD 660
Query: 567 SKITLVNPPVVVTAINLKTTINEKQNINEIVSASVVSCNMVKIDTPMLASEWKRPGMLTH 626
+ PP+ V +I ++T +N K+N E+V+ S + +I+ P + +
Sbjct: 661 TTSPRETPPLTVMSIAIRTVVNHKENKQELVAVSARTWTDHQIEDPTPPEQLP----CSV 716
Query: 627 FTVIRKLDGNIFPMGFNTEVTDRNIKAGSNVLCVESSERALLNRLMLQLHKMDSDVLVGH 686
FT +R L G +FP GF E IK + ER LLN L+ Q++ D DV+VGH
Sbjct: 717 FTAVRPL-GTMFPPGFEAEARKGRIK-----IHTLKYERMLLNALLAQIYNADPDVIVGH 770
Query: 687 NISGFDLDVLLHRSQACRVPSSMWSKLGRLNRSTMPKLDRRGKTFGFGADPAIMSCVAGR 746
+G LDVLLHR + R + WS++GR R PKL ++G + +AGR
Sbjct: 771 EFNGVSLDVLLHRMRDLR--ADHWSRVGRFRRPKWPKL-KQGLN---------LKILAGR 818
Query: 747 LLCDTYLCS---RDLLKEVSYSLTHLAKTQLNQSRKEVAPHEVPKMFQ----TAKSLMEL 799
L+CD L S + ++ ++SLT + T L R+++ P E F + + LM
Sbjct: 819 LVCD--LASDNGKSMITSTTWSLTEMCGTHLKIQREDIDPEETASFFDSLAPSPERLMNF 876
Query: 800 IEYGETDAWLSMELMFYLSVLPLTRQLTNLSGNLWGKTLQGARAQRVEYLLLHEFHKKKY 859
+ + E D + M + + +LPLT+QLTNL+GN W KTL G RA+R EY+LLH+FH++KY
Sbjct: 877 VRHCEVDTFFQMAIAAKVQILPLTKQLTNLAGNSWNKTLNGGRAERNEYILLHDFHRQKY 936
Query: 860 IVPDKFSNYAK-------ETKLTKRRVTHGVDDGNFDDADINDANYHNDASESDHKKNKK 912
I PDK S + K E K R ++G D+S S N K
Sbjct: 937 ICPDKISAWEKKQIQQAAELKAKARAKSNG---------------GAADSSASTTAANSK 981
Query: 913 AASYAGGLVLEPKKGLYDKYILLLDFNSLYPSIIQEYNICFTTVER-------------- 958
+ GGLV EPK+GL+DKYIL++DFNSLYPSIIQE+NI FTTVER
Sbjct: 982 KDKFKGGLVFEPKRGLWDKYILVMDFNSLYPSIIQEFNIDFTTVERPPTQGIEDDEIGVA 1041
Query: 959 ----SSD-------------DSFPRLPSSKT-TGVLPELLKKLVKLRREKKTWMKTASGL 1000
SSD D P +PSS GVLP ++ +LV RR+ K+ MK S
Sbjct: 1042 AATASSDTAGEAGADAAADVDKIPDVPSSDVEQGVLPRIIAQLVARRRQVKSLMKDKSAT 1101
Query: 1001 KRQ--QLDIEQQALKLTANSMYGCLGFSNSRFYAKPLAELITLQGREILQSTVDLVQNNL 1058
Q Q +I+Q ALKLTANSMYGCLGF NSRFYA+PLA L T +GREIL +T DL ++ L
Sbjct: 1102 PSQLLQWNIKQLALKLTANSMYGCLGFENSRFYARPLAALTTFKGREILTATKDLAESML 1161
Query: 1059 NLEVIYGDTDSIMIYSGLDDIAKATSISKKVIQEVNKKYRCLEIDLDGLYKRMLLLKKKK 1118
L+VIYGDTDS+MI + + +A I ++ + VN++YR LEID+DG+++RMLLL+KKK
Sbjct: 1162 -LDVIYGDTDSVMINTNATEYREALRIGQEFKKSVNERYRLLEIDIDGVFERMLLLQKKK 1220
Query: 1119 YAAVKVQFKDGTPYEVIERKGLDIVRRDWSLLAKDLGDFCLTQILSGGSCEDVVESIHNS 1178
YAAV V + E+ KGLD+ RR++S L+K++ ++ L QILSG + E VVE IH
Sbjct: 1221 YAAVLVDEEGKRSTEI---KGLDMKRREYSALSKNVSNYVLEQILSGQATELVVEHIHEY 1277
Query: 1179 LMKVQEEMRNGQVALEKYVITKTLTKPPEAYPDAKNQPHVLVAQRLKQQGYTSGCSVGDT 1238
L + +++ G+V L+ ++I K L K PE YPD K+QPHV VA R+K +G +GD
Sbjct: 1278 LSDISTKIKMGEVGLDDFIIYKRLGKNPEDYPDVKSQPHVQVALRMKTRG--GNARMGDV 1335
Query: 1239 IPYVICCEQGGSSGSATGIALRARHPDELKQEQGTWLIDIDYYLSQQIHPVISRLCASIQ 1298
IPY+ C + G+S + T A RA HPDEL+++ ID ++YL+ QI P + RLC SI+
Sbjct: 1336 IPYIFCLGEDGTSSTKTAQAERAHHPDELRRKDSELKIDYEHYLALQILPPVERLCESIE 1395
Query: 1299 GTSPERLADCLGLDTSKFQHKS-SEASDDPTSSLLFAGDDEESEKPTSSGTDESDYNFWR 1357
GT RLA+CLGLD SK+ H S S A FA D + E
Sbjct: 1396 GTDRSRLAECLGLDPSKYSHVSHSGAGSGGAVGREFATLDSQIPDEVRFAQCEP-----L 1450
Query: 1358 KLCCPKCFENGA-------------------------------------------GRISA 1374
KL CP C E+ +
Sbjct: 1451 KLTCPSCRESSTFLGPAHRAASSAIKVLGDSTNTQRSEPNAISTKGIRCTNAACQRMLPL 1510
Query: 1375 AMIANQVKRQAEKFVLMYYRGLLMCDDETCKHTTRSVSFR-----LVGDSERGTVCP--- 1426
A +A Q++ FV YY G C D C TR S V D++ +
Sbjct: 1511 ATMAIQLELAIRSFVERYYAGWTECSDPNCGSRTRLASVYAKRCVAVHDAKSAALLDATS 1570
Query: 1427 ---NYPRCNGHLNRKYTEADLYKQLSYFCHVFDTVCYIEKMEA 1466
++ C G + Y + LY QL Y +FD+ EK+ A
Sbjct: 1571 TTGSHLACRGRVEPVYRDKQLYDQLIYLESLFDSSRIREKVTA 1613
>gb|AAP13534.1| polymerase (DNA directed), alpha [Homo sapiens]
gi|60392197|sp|P09884|DPOA_HUMAN DNA polymerase alpha
catalytic subunit
Length = 1462
Score = 685 bits (1768), Expect = 0.0
Identities = 445/1170 (38%), Positives = 640/1170 (54%), Gaps = 142/1170 (12%)
Query: 390 SCCVVVKNMQRCVYAIPSHPLHSTNEMIQLEKDVQESRISPADFRKKLQDAVSDTKNEIA 449
SCCV+VKN++R +Y +P N + + IS D ++ + ++ TK +I
Sbjct: 375 SCCVMVKNIERTLYFLPREMKIDLNTGKETG-----TPISMKDVYEEFDEKIA-TKYKIM 428
Query: 450 KHLVDLGVSSFSMAPVKRKYAFERTDIPAGENYVVKINYLFKDTALPVDLKGKSFCALLG 509
K F PV++ YAFE D+P Y+ ++ Y + LP DLKG++F + G
Sbjct: 429 K---------FKSKPVEKNYAFEIPDVPEKSEYL-EVKYSAEMPQLPQDLKGETFSHVFG 478
Query: 510 ARNSALELFLIKRKIKGPSWLQVSNFSTCSASQRVSWCKFEVIVDSPKDIRASSPSSSKI 569
S+LELFL+ RKIKGP WL+V S +Q VSWCK E + P + S
Sbjct: 479 TNTSSLELFLMNRKIKGPCWLEVK--SPQLLNQPVSWCKVEAMALKPDLVNVIKDVSP-- 534
Query: 570 TLVNPPVVVTAINLKTTINEKQNINEIVSASVVSCNMVKIDTPMLASEWKRPGMLTHFTV 629
PP+VV A ++KT N K + NEI++ + + + +D +P +HF V
Sbjct: 535 ----PPLVVMAFSMKTMQNAKNHQNEIIAMAALVHHSFALDKAA-----PKPPFQSHFCV 585
Query: 630 IRKLDGNIFPMGFNTEVTDRNIKAGSNVLCVESSERALLNRLMLQLHKMDSDVLVGHNIS 689
+ K IFP F + +N+K V ++ER LL + ++HK+D D++VGHNI
Sbjct: 586 VSKPKDCIFPYAFKEVIEKKNVKVE-----VAATERTLLGFFLAKVHKIDPDIIVGHNIY 640
Query: 690 GFDLDVLLHRSQACRVPSSMWSKLGRLNRSTMPKLDRRGKTFGFGADPAIMSCVAGRLLC 749
GF+L+VLL R C+ P WSK+GRL RS MPKL R GFG A GR++C
Sbjct: 641 GFELEVLLQRINVCKAPH--WSKIGRLKRSNMPKLGGRS---GFGERNA----TCGRMIC 691
Query: 750 DTYLCSRDLLKEVSYSLTHLAKTQLNQSRKEVAPHEVPKMFQTAKSLMELIEYGETDAWL 809
D + +++L++ SY L+ L + L R + + M+ + L+ L+E+ DA
Sbjct: 692 DVEISAKELIRCKSYHLSELVQQILKTERVVIPMENIQNMYSESSQLLYLLEHTWKDAKF 751
Query: 810 SMELMFYLSVLPLTRQLTNLSGNLWGKTLQGARAQRVEYLLLHEFHKKKYIVPDKFSNYA 869
+++M L+VLPL Q+TN++GN+ +TL G R++R E+LLLH F++ YIVPDK
Sbjct: 752 ILQIMCELNVLPLALQITNIAGNIMSRTLMGGRSERNEFLLLHAFYENNYIVPDKQIFRK 811
Query: 870 KETKLTKRRVTHGVDDGNFDDADINDANYHNDASESDHKKNKKAASYAGGLVLEPKKGLY 929
+ KL D + D + +KK +K A+YAGGLVL+PK G Y
Sbjct: 812 PQQKL-------------------GDEDEEIDGDTNKYKKGRKKAAYAGGLVLDPKVGFY 852
Query: 930 DKYILLLDFNSLYPSIIQEYNICFTTVERSSDDS-----------FPRLPS-SKTTGVLP 977
DK+ILLLDFNSLYPSIIQE+NICFTTV+R + ++ P LP S G+LP
Sbjct: 853 DKFILLLDFNSLYPSIIQEFNICFTTVQRVASEAQKVTEDGEQEQIPELPDPSLEMGILP 912
Query: 978 ELLKKLVKLRREKKTWMKTASGLKRQ---QLDIEQQALKLTANSMYGCLGFSNSRFYAKP 1034
++KLV+ R++ K MK L Q DI Q+ALKLTANSMYGCLGFS SRFYAKP
Sbjct: 913 REIRKLVERRKQVKQLMKQQD-LNPDLILQYDIRQKALKLTANSMYGCLGFSYSRFYAKP 971
Query: 1035 LAELITLQGREILQSTVDLVQNNLNLEVIYGDTDSIMIYSGLDDIAKATSISKKVIQEVN 1094
LA L+T +GREIL T ++VQ +NLEVIYGDTDSIMI + ++ + + KV EVN
Sbjct: 972 LAALVTYKGREILMHTKEMVQK-MNLEVIYGDTDSIMINTNSTNLEEVFKLGNKVKSEVN 1030
Query: 1095 KKYRCLEIDLDGLYKRMLLLKKKKYAAVKVQ-FKDGTPYEVIERKGLDIVRRDWSLLAKD 1153
K Y+ LEID+DG++K +LLLKKKKYAA+ V+ DG E KGLDIVRRDW LAKD
Sbjct: 1031 KLYKLLEIDIDGVFKSLLLLKKKKYAALVVEPTSDGNYVTKQELKGLDIVRRDWCDLAKD 1090
Query: 1154 LGDFCLTQILSGGSCEDVVESIHNSLMKVQEEMRNGQVALEKYVITKTLTKPPEAYPDAK 1213
G+F + QILS S + +VE+I L+++ E + NG V + ++ I K LTK P+ YPD K
Sbjct: 1091 TGNFVIGQILSDQSRDTIVENIQKRLIEIGENVLNGSVPVSQFEINKALTKDPQDYPDKK 1150
Query: 1214 NQPHVLVAQRLKQQGYTSGCSVGDTIPYVICCEQGGSSGSATGIALRARHPDELKQEQGT 1273
+ PHV VA + QG GDT+ YVIC Q GS+ +A+ RA P++L Q+Q
Sbjct: 1151 SLPHVHVALWINSQGGRK-VKAGDTVSYVIC--QDGSNLTASQ---RAYAPEQL-QKQDN 1203
Query: 1274 WLIDIDYYLSQQIHPVISRLCASIQGTSPERLADCLGLDTSKFQ----HKSSEASDDPTS 1329
ID YYL+QQIHPV++R+C I G +A LGLD ++F+ HK E +
Sbjct: 1204 LTIDTQYYLAQQIHPVVARICEPIDGIDAVLIATWLGLDPTQFRVHHYHKDEE------N 1257
Query: 1330 SLLFAGDDEESEKPTSSGTDESDYNFWRKLCCP-------KCFEN---GAG--------R 1371
L G + TDE Y + CP ++N G+G R
Sbjct: 1258 DALLGGPAQL--------TDEEKYRDCERFKCPCPTCGTENIYDNVFDGSGTDMEPSLYR 1309
Query: 1372 IS-----------AAMIANQVKRQAEKFVLMYYRGLLMCDDETCKHTTRSVSFRLVGDSE 1420
S ++N++ +F+ YY G L+C++ TC++ TR + + S
Sbjct: 1310 CSNIDCKASPLTFTVQLSNKLIMDIRRFIKKYYDGWLICEEPTCRNRTRHLPLQF---SR 1366
Query: 1421 RGTVCPNYPRCNGHLNRKYTEADLYKQLSYFCHVFDTVCYIEKMEA-KSRIPIEKELIKI 1479
G +CP + L +Y++ LY QL ++ ++FD C +EK+ + ++K+
Sbjct: 1367 TGPLCPACMKAT--LQPEYSDKSLYTQLCFYRYIFDAECALEKLTTDHEKDKLKKQFFTP 1424
Query: 1480 RPIVDL--AASTIQKIRDRCAFGWVKLQDL 1507
+ + D +T ++ R + V L L
Sbjct: 1425 KVLQDYRKLKNTAEQFLSRSGYSEVNLSKL 1454
>emb|CAA29920.1| unnamed protein product [Homo sapiens] gi|8393995|ref|NP_058633.1|
polymerase (DNA-directed), alpha [Homo sapiens]
Length = 1462
Score = 685 bits (1767), Expect = 0.0
Identities = 443/1170 (37%), Positives = 640/1170 (53%), Gaps = 142/1170 (12%)
Query: 390 SCCVVVKNMQRCVYAIPSHPLHSTNEMIQLEKDVQESRISPADFRKKLQDAVSDTKNEIA 449
SCCV+VKN++R +Y +P N + + IS D ++ + ++ TK +I
Sbjct: 375 SCCVMVKNIERTLYFLPREMKIDLNTGKETG-----TPISMKDVYEEFDEKIA-TKYKIM 428
Query: 450 KHLVDLGVSSFSMAPVKRKYAFERTDIPAGENYVVKINYLFKDTALPVDLKGKSFCALLG 509
K F PV++ YAFE D+P Y+ ++ Y + LP DLKG++F + G
Sbjct: 429 K---------FKSKPVEKNYAFEIPDVPEKSEYL-EVKYSAEMPQLPQDLKGETFSHVFG 478
Query: 510 ARNSALELFLIKRKIKGPSWLQVSNFSTCSASQRVSWCKFEVIVDSPKDIRASSPSSSKI 569
S+LELFL+ RKIKGP WL+V + + +Q VSWCK E + P + S
Sbjct: 479 TNTSSLELFLMNRKIKGPCWLEVKK--STALNQPVSWCKVEAMALKPDLVNVIKDVSP-- 534
Query: 570 TLVNPPVVVTAINLKTTINEKQNINEIVSASVVSCNMVKIDTPMLASEWKRPGMLTHFTV 629
PP+VV A ++KT N K + NEI++ + + + +D +P +HF V
Sbjct: 535 ----PPLVVMAFSMKTMQNAKNHQNEIIAMAALVHHSFALDKAA-----PKPPFQSHFCV 585
Query: 630 IRKLDGNIFPMGFNTEVTDRNIKAGSNVLCVESSERALLNRLMLQLHKMDSDVLVGHNIS 689
+ K IFP F + +N+K V ++ER LL + ++HK+D D++VGHNI
Sbjct: 586 VSKPKDCIFPYAFKEVIEKKNVKVE-----VAATERTLLGFFLAKVHKIDPDIIVGHNIY 640
Query: 690 GFDLDVLLHRSQACRVPSSMWSKLGRLNRSTMPKLDRRGKTFGFGADPAIMSCVAGRLLC 749
GF+L+VLL R C+ P WSK+GRL RS MPKL R GFG A GR++C
Sbjct: 641 GFELEVLLQRINVCKAPH--WSKIGRLKRSNMPKLGGRS---GFGERNA----TCGRMIC 691
Query: 750 DTYLCSRDLLKEVSYSLTHLAKTQLNQSRKEVAPHEVPKMFQTAKSLMELIEYGETDAWL 809
D + +++L++ SY L+ L + L R + + M+ + L+ L+E+ DA
Sbjct: 692 DVEISAKELIRCKSYHLSELVQQILKTERVVIPMENIQNMYSESSQLLYLLEHTWKDAKF 751
Query: 810 SMELMFYLSVLPLTRQLTNLSGNLWGKTLQGARAQRVEYLLLHEFHKKKYIVPDKFSNYA 869
+++M L+VLPL Q+TN++GN+ +TL G R++R E+LLLH F++ YIVPDK
Sbjct: 752 ILQIMCELNVLPLALQITNIAGNIMSRTLMGGRSERNEFLLLHAFYENNYIVPDKQIFRK 811
Query: 870 KETKLTKRRVTHGVDDGNFDDADINDANYHNDASESDHKKNKKAASYAGGLVLEPKKGLY 929
+ KL D + D + +KK +K +YAGGLVL+PK G Y
Sbjct: 812 PQQKL-------------------GDEDEEIDGDTNKYKKGRKKGAYAGGLVLDPKVGFY 852
Query: 930 DKYILLLDFNSLYPSIIQEYNICFTTVERSSDDS-----------FPRLPS-SKTTGVLP 977
DK+ILLLDFNSLYPSIIQE+NICFTTV+R + ++ P LP S G+LP
Sbjct: 853 DKFILLLDFNSLYPSIIQEFNICFTTVQRVASEAQKVTEDGEQEQIPELPDPSLEMGILP 912
Query: 978 ELLKKLVKLRREKKTWMKTASGLKRQ---QLDIEQQALKLTANSMYGCLGFSNSRFYAKP 1034
++KLV+ R++ K MK L Q DI Q+ALKLTANSMYGCLGFS SRFYAKP
Sbjct: 913 REIRKLVERRKQVKQLMKQQD-LNPDLILQYDIRQKALKLTANSMYGCLGFSYSRFYAKP 971
Query: 1035 LAELITLQGREILQSTVDLVQNNLNLEVIYGDTDSIMIYSGLDDIAKATSISKKVIQEVN 1094
LA L+T +GREIL T ++VQ +NLEVIYGDTDSIMI + ++ + + KV EVN
Sbjct: 972 LAALVTYKGREILMHTKEMVQK-MNLEVIYGDTDSIMINTNSTNLEEVFKLGNKVKSEVN 1030
Query: 1095 KKYRCLEIDLDGLYKRMLLLKKKKYAAVKVQ-FKDGTPYEVIERKGLDIVRRDWSLLAKD 1153
K Y+ LEID+DG++K +LLLKKKKYAA+ V+ DG E KGLDIVRRDW LAKD
Sbjct: 1031 KLYKLLEIDIDGVFKSLLLLKKKKYAALVVEPTSDGNYVTKQELKGLDIVRRDWCDLAKD 1090
Query: 1154 LGDFCLTQILSGGSCEDVVESIHNSLMKVQEEMRNGQVALEKYVITKTLTKPPEAYPDAK 1213
G+F + QILS S + +VE+I L+++ E + NG V + ++ I K LTK P+ YPD K
Sbjct: 1091 TGNFVIGQILSDQSRDTIVENIQKRLIEIGENVLNGSVPVSQFEINKALTKDPQDYPDKK 1150
Query: 1214 NQPHVLVAQRLKQQGYTSGCSVGDTIPYVICCEQGGSSGSATGIALRARHPDELKQEQGT 1273
+ PHV VA + QG GDT+ YVIC Q GS+ +A+ RA P++L Q+Q
Sbjct: 1151 SLPHVHVALWINSQGGRK-VKAGDTVSYVIC--QDGSNLTASQ---RAYAPEQL-QKQDN 1203
Query: 1274 WLIDIDYYLSQQIHPVISRLCASIQGTSPERLADCLGLDTSKFQ----HKSSEASDDPTS 1329
ID YYL+QQIHPV++R+C I G +A LGLD ++F+ HK E +
Sbjct: 1204 LTIDTQYYLAQQIHPVVARICEPIDGIDAVLIATWLGLDPTQFRVHHYHKDEE------N 1257
Query: 1330 SLLFAGDDEESEKPTSSGTDESDYNFWRKLCCP-------KCFEN---GAG--------R 1371
L G + TDE Y + CP ++N G+G R
Sbjct: 1258 DALLGGPAQL--------TDEEKYRDCERFKCPCPTCGTENIYDNVFDGSGTDMEPSLYR 1309
Query: 1372 IS-----------AAMIANQVKRQAEKFVLMYYRGLLMCDDETCKHTTRSVSFRLVGDSE 1420
S ++N++ +F+ YY G L+C++ TC++ TR + + S
Sbjct: 1310 CSNIDCKASPLTFTVQLSNKLIMDIRRFIKKYYDGWLICEEPTCRNRTRHLPLQF---SR 1366
Query: 1421 RGTVCPNYPRCNGHLNRKYTEADLYKQLSYFCHVFDTVCYIEKMEA-KSRIPIEKELIKI 1479
G +CP + L +Y++ LY QL ++ ++FD C +EK+ + ++K+
Sbjct: 1367 TGPLCPACMKAT--LQPEYSDKSLYTQLCFYRYIFDAECALEKLTTDHEKDKLKKQFFTP 1424
Query: 1480 RPIVDL--AASTIQKIRDRCAFGWVKLQDL 1507
+ + D +T ++ R + V L L
Sbjct: 1425 KVLQDYRKLKNTAEQFLSRSGYSEVNLSKL 1454
>dbj|BAD92009.1| DNA polymerase alpha catalytic subunit [Iguana iguana]
Length = 1441
Score = 685 bits (1767), Expect = 0.0
Identities = 441/1121 (39%), Positives = 630/1121 (55%), Gaps = 145/1121 (12%)
Query: 388 YQSCCVVVKNMQRCVYAIPSHPLHSTNEMIQLEKDVQESRISPADFRKKLQDAVS--DTK 445
Y SCCV VKN++R +Y +P +ESRI K+ ++ V+ D
Sbjct: 345 YVSCCVTVKNIERTIYLLP-----------------RESRIDKCS-GKETENPVTMMDVY 386
Query: 446 NEIAKHLVD-LGVSSFSMAPVKRKYAFERTDIPAGENYVVKINYLFKDTALPVDLKGKSF 504
E H+ + + + V++ YAFE D+PA +Y+ ++ Y + + LP DLKG++F
Sbjct: 387 QEFNDHVAEKFKIMKYKSKKVEKNYAFEIPDVPAKSDYL-EVRYSAEYSRLPQDLKGETF 445
Query: 505 CALLGARNSALELFLIKRKIKGPSWLQVSNFSTCSASQRVSWCKFEVIVDSPKDIRASSP 564
+ G S+LEL L+ RKIKGP WL++ N +SQ VSWCK E++ P +
Sbjct: 446 SHVFGTNTSSLELLLMNRKIKGPGWLEIKNPQL--SSQAVSWCKVELVALKPAFVNVVKD 503
Query: 565 SSSKITLVNPPVVVTAINLKTTINEKQNINEIVSASVVSCNMVKIDTPMLASEWKRPGML 624
L PP+V+ ++++KT N K + NEI+ + + + +D P
Sbjct: 504 ------LPPPPLVIMSLSMKTVQNTKTHQNEIMVITALVHHKFCLDKAPPV-----PPFQ 552
Query: 625 THFTVIRKLDGNIFPMGFNTEVTDRNIKAGSNVLCVESSERALLNRLMLQLHKMDSDVLV 684
THF VI K + IFP F V +N K + + ++ER LL + ++HK+D DV+V
Sbjct: 553 THFCVISKPNDCIFPYDFKEIVKTKNAK-----IEIATTERTLLGFFLAKVHKIDPDVIV 607
Query: 685 GHNISGFDLDVLLHRSQACRVPSSMWSKLGRLNRSTMPKLDRRGKTFGFGADPAIMSCVA 744
GHNI GFDL++LL R C+VP WSK+GRL RS MPKL R GF A +
Sbjct: 608 GHNIYGFDLELLLQRINFCKVPH--WSKIGRLRRSNMPKLGGRS---GF----AEKNATC 658
Query: 745 GRLLCDTYLCSRDLLKEVSYSLTHLAKTQLNQSRKEVAPHEVPKMFQTAKSLMELIEYGE 804
GR++CD + +++L++ SY LT L L R V P E+ M+ + L+ ++E
Sbjct: 659 GRMICDVEISAKELIRCKSYHLTELVNQILKVERITVPPEEIRNMYSDPRQLLYMVENTW 718
Query: 805 TDAWLSMELMFYLSVLPLTRQLTNLSGNLWGKTLQGARAQRVEYLLLHEFHKKKYIVPDK 864
TDA +++M L+VLPL Q+TN++GN+ +TL G RA+R EYLLLH F++K +IVPDK
Sbjct: 719 TDAKYILQIMCDLNVLPLALQITNIAGNVMSRTLMGGRAERNEYLLLHAFYEKNFIVPDK 778
Query: 865 FSNYAKETKLTKRRVTHGVDDGNFDDADINDANYHNDASESDHKKNKKAASYAGGLVLEP 924
+ K T++++ D ++ D ++S K +K A+Y+GGLVLEP
Sbjct: 779 -----QLFKKTQKQLE-------------EDEDFEGDQNKS--KTGRKKAAYSGGLVLEP 818
Query: 925 KKGLYDKYILLLDFNSLYPSIIQEYNICFTTVERSS-----------DDSFPRLP-SSKT 972
K G YDK+ILLLDFNSLYPSIIQE+NICFTTV R S ++ P LP SS
Sbjct: 819 KVGFYDKFILLLDFNSLYPSIIQEFNICFTTVHRVSSSLHKNTEDGEEEEIPELPDSSLD 878
Query: 973 TGVLPELLKKLVKLRREKKTWMK--TASGLKRQQLDIEQQALKLTANSMYGCLGFSNSRF 1030
G+LP+ ++KLV+ RR+ K MK + Q DI Q+ALKLTANSMYGCLGFS SRF
Sbjct: 879 MGILPKEIRKLVERRRQVKQLMKQPDLNSDLYLQYDIRQKALKLTANSMYGCLGFSYSRF 938
Query: 1031 YAKPLAELITLQGREILQSTVDLVQNNLNLEVIYGDTDSIMIYSGLDDIAKATSISKKVI 1090
YAKPLA L+T +GREIL T ++V+ +NLEVIYGDTDSIMI + + ++ + + K+
Sbjct: 939 YAKPLAALVTFKGREILMHTKEMVE-KMNLEVIYGDTDSIMINTNITNLEEVFKLGNKIK 997
Query: 1091 QEVNKKYRCLEIDLDGLYKRMLLLKKKKYAAVKVQ-FKDGTPYEVIERKGLDIVRRDWSL 1149
EVNK Y+ LEID+DG++K +LLLKKKKYAA+ V+ DG E KGLDIVRRDW
Sbjct: 998 SEVNKLYKLLEIDIDGIFKSLLLLKKKKYAALVVEPTGDGKYITKQELKGLDIVRRDWCD 1057
Query: 1150 LAKDLGDFCLTQILSGGSCEDVVESIHNSLMKVQEEMRNGQVALEKYVITKTLTKPPEAY 1209
LAK+ G++ ++QILS + +VE+I L+++ E + NG V ++++ I K LTK P+ Y
Sbjct: 1058 LAKETGNYIISQILSDQFRDVIVENIQRRLIQIGENVVNGSVPIKQFEINKALTKDPQDY 1117
Query: 1210 PDAKNQPHVLVAQRLKQQGYTSGCSVGDTIPYVICCEQGGSSGSATGIALRARHPDELKQ 1269
PD K+ PHV VA + Q GDT+ YVIC Q GS+ SA + RA P++LK+
Sbjct: 1118 PDKKSLPHVHVALWINSQEGRK-LKAGDTVSYVIC--QDGSNLSA---SQRAYAPEQLKK 1171
Query: 1270 EQGTWLIDIDYYLSQQIHPVISRLCASIQGTSPERLADCLGLDTSKFQ-----HKSSEAS 1324
++ ID YYLSQQIHPV++R+C I G +A LGLD S+F+ HK E
Sbjct: 1172 QENL-AIDTQYYLSQQIHPVVARICEPIDGIDSVLIAAWLGLDPSQFKVYHHYHKDEEND 1230
Query: 1325 DDPTSSLLFAGDDEESEKPTSSGTDESDYNFWR--KLCCPKC--------FENGAGRISA 1374
D L G + TDE Y K CPKC NG+ +
Sbjct: 1231 D------LLGGPVQL--------TDEEKYKDCERFKFACPKCGTENIYDNVVNGSDMMIE 1276
Query: 1375 A-------------------MIANQVKRQAEKFVLMYYRGLLMCDDETCKHTTRSVSFRL 1415
A I N++ ++ YY L C++ TC++ TR + R
Sbjct: 1277 ASLLYCSKKECNESPWKYLMQINNRLILDIRSYIKKYYTSWLRCEEPTCQYRTRRLPLRF 1336
Query: 1416 VGDSERGTVCPNYPRCNGHLNRKYTEADLYKQLSYFCHVFD 1456
S+ G +CP + + R+Y++ L+ QL ++ ++FD
Sbjct: 1337 ---SKNGPLCPVCKK--AVVKREYSDKVLFTQLCFYRYIFD 1372
>dbj|BAD92007.1| DNA polymerase alpha catalytic subunit [Ambystoma mexicanum]
Length = 1409
Score = 672 bits (1735), Expect = 0.0
Identities = 432/1147 (37%), Positives = 622/1147 (53%), Gaps = 120/1147 (10%)
Query: 390 SCCVVVKNMQRCVYAIPSHPLHSTNEMIQLEKDVQESRISPADFRKKLQDAVSDTKNEIA 449
SCC+ VKN++R VY +P E V S + + + IA
Sbjct: 322 SCCLTVKNIERTVYLLPR------------ETQVDLSSGKETGTPVSMMNVYQEFNERIA 369
Query: 450 KHLVDLGVSSFSMAPVKRKYAFERTDIPAGENYVVKINYLFKDTALPVDLKGKSFCALLG 509
+ + F +++ YAFE D+PA Y+ ++ Y + LP DLKG++F + G
Sbjct: 370 EKFK---LMKFKSKKIEKNYAFEIPDVPANSEYL-EVRYSAELPPLPKDLKGETFSHVFG 425
Query: 510 ARNSALELFLIKRKIKGPSWLQVSNFSTCSASQRVSWCKFEVIVDSPKDIRASSPSSSKI 569
S+LELFL+ RKIKGPSWL++ + Q VSWCK E + P +
Sbjct: 426 TNTSSLELFLLSRKIKGPSWLEIKTPQL--SFQPVSWCKVEAVALKPDLVSVVKD----- 478
Query: 570 TLVNPPVVVTAINLKTTINEKQNINEIVSASVVSCNMVKIDTPMLASEWKRPGMLTHFTV 629
L PP+VV A+++KT N K + NEIV+ SV++ + +D +P THF V
Sbjct: 479 -LPPPPLVVMALSMKTVQNAKTHQNEIVAISVLAHHKFPLDKAP-----PQPPFQTHFCV 532
Query: 630 IRKLDGNIFPMGFNTEVTDRNIKAGSNVLCVESSERALLNRLMLQLHKMDSDVLVGHNIS 689
+ K IFP + + +N + V +ER LL L+ ++HK+D DV+VGH+I
Sbjct: 533 VCKPSDCIFPYDYKEAIKQKNAN-----IEVALTERTLLGFLLAKIHKIDPDVIVGHDIY 587
Query: 690 GFDLDVLLHRSQACRVPSSMWSKLGRLNRSTMPKLDRRGKTFGFGADPAIMSCVAGRLLC 749
GFDL+VLL R C+VP WSK+GRL RS MPKL R GF A + GR++C
Sbjct: 588 GFDLEVLLQRINVCKVPH--WSKIGRLRRSIMPKLGGRS---GF----AERNAACGRMIC 638
Query: 750 DTYLCSRDLLKEVSYSLTHLAKTQLNQSRKEVAPHEVPKMFQTAKSLMELIEYGETDAWL 809
D + +++L++ SY L+ L L R + + + + L+ ++E+ D
Sbjct: 639 DVQISAKELIRCKSYHLSELVHQILKTERLIIPGENIRNYYSDSPQLLYMLEHTWLDTKF 698
Query: 810 SMELMFYLSVLPLTRQLTNLSGNLWGKTLQGARAQRVEYLLLHEFHKKKYIVPDKFSNYA 869
+++M L+VLPL Q+TN++GN+ +TL G R++R EYLLLH F++ +IVPDK
Sbjct: 699 ILQIMCELNVLPLALQITNIAGNVMSRTLMGGRSERNEYLLLHAFYENNFIVPDK----- 753
Query: 870 KETKLTKRRVTHGVDDGNFDDADINDANYHNDASESDHKKNKKAASYAGGLVLEPKKGLY 929
K+ + + VD+ D + ND + KK +K A+YAGGLVL+PK G Y
Sbjct: 754 ---PTFKKPLQNLVDE---------DEDIEND--QGKQKKVRKKAAYAGGLVLDPKVGFY 799
Query: 930 DKYILLLDFNSLYPSIIQEYNICFTTVER-----------SSDDSFPRLPSSKTT-GVLP 977
DK+ILLLDFNSLYPSIIQE+NICFTTV+R D P+LP G+LP
Sbjct: 800 DKFILLLDFNSLYPSIIQEFNICFTTVQRLDSNAQKMPEGEEQDDIPQLPDPDLELGILP 859
Query: 978 ELLKKLVKLRREKKTWMKTA--SGLKRQQLDIEQQALKLTANSMYGCLGFSNSRFYAKPL 1035
++KLV+ RR+ K MK + + Q DI Q+ALKLTANSMYGCLGFS SRFYAKPL
Sbjct: 860 REIRKLVERRRQVKQLMKQSDLNPDLYMQYDIRQKALKLTANSMYGCLGFSFSRFYAKPL 919
Query: 1036 AELITLQGREILQSTVDLVQNNLNLEVIYGDTDSIMIYSGLDDIAKATSISKKVIQEVNK 1095
A L+T +GREIL T D+VQ +NLEVIYGDTDSIMI + ++ + + KV EVNK
Sbjct: 920 AALVTHKGREILLHTRDMVQK-MNLEVIYGDTDSIMINTNSTNLEEVFKLGNKVKSEVNK 978
Query: 1096 KYRCLEIDLDGLYKRMLLLKKKKYAAVKVQ-FKDGTPYEVIERKGLDIVRRDWSLLAKDL 1154
Y+ LEID+DG++K +LLLKKKKYAA+ ++ DG E KGLDIVRRDW LAK+
Sbjct: 979 LYKQLEIDIDGVFKSLLLLKKKKYAALTMEPAGDGKYVTKQELKGLDIVRRDWCDLAKET 1038
Query: 1155 GDFCLTQILSGGSCEDVVESIHNSLMKVQEEMRNGQVALEKYVITKTLTKPPEAYPDAKN 1214
G++ +TQILS + +VE+I L+++ E + NG + + +Y I K LTK P+ YPD K+
Sbjct: 1039 GNYIITQILSDQPRDTIVENIQKQLIEIGENVVNGSIPINQYEINKALTKDPQDYPDKKS 1098
Query: 1215 QPHVLVAQRLKQQGYTSGCSVGDTIPYVICCEQGGSSGSATGIALRARHPDELKQEQGTW 1274
PHV VA + QG GDT+ Y+IC + S S AL E Q+Q
Sbjct: 1099 LPHVHVALWINSQGGRK-MKAGDTVSYIICQDGSNLSASQRAYAL------EQLQKQDNL 1151
Query: 1275 LIDIDYYLSQQIHPVISRLCASIQGTSPERLADCLGLDTSKFQHKSSEASDDPTSSLLFA 1334
ID YYLSQQ+HPV++R+C I G +A LGLD S+F+ +S D+ ++L
Sbjct: 1152 AIDTQYYLSQQVHPVVARICEPIDGIDSALIAAWLGLDPSQFRVQSHYQKDEENDAMLGG 1211
Query: 1335 GD---DEESEKP--------TSSGTDESDYNFW-----------RKLCCPKCFENGAGRI 1372
DEE K + GT+ N + ++ C P+C + +
Sbjct: 1212 PSQITDEEKYKDCERFKFTCPACGTEGIYDNAFDGSGALMEPILKRCCKPEC--DASPMH 1269
Query: 1373 SAAMIANQVKRQAEKFVLMYYRGLLMCDDETCKHTTRSVSFRLVGDSERGTVCPNYPRCN 1432
+ N++ + + YY +C++ TC++ TR + S G +C +
Sbjct: 1270 FVIQLQNKLHLDIRRHIKKYYSAWFICEEPTCQNRTRRLPLNF---SRNGPICQACMKAT 1326
Query: 1433 GHLNRKYTEADLYKQLSYFCHVFDTVCYIEKMEAKSRIPIEKELIKIRPI--VDLAASTI 1490
L +Y + LY QL ++ ++FD +E + KS +EK L+K + D+ +
Sbjct: 1327 --LRPEYPDKALYTQLCFYRYIFD----LEYTKEKSVSDVEKRLLKDAELDGTDVVYKRL 1380
Query: 1491 QKIRDRC 1497
+ DRC
Sbjct: 1381 KGTVDRC 1387
>emb|CAA09720.1| DNA polymerase alpha subunit I [Rattus norvegicus]
gi|6015013|sp|O89042|DPOA_RAT DNA polymerase alpha
catalytic subunit
Length = 1451
Score = 672 bits (1733), Expect = 0.0
Identities = 435/1151 (37%), Positives = 634/1151 (54%), Gaps = 133/1151 (11%)
Query: 380 LFVWQGTLYQSCCVVVKNMQRCVYAIPSHPLHSTNEMIQLEKDVQESRISPADFRKKLQD 439
++V + SCCV+VKN++R +Y +P ++++ + + +P ++D
Sbjct: 372 VWVESAKTHVSCCVMVKNIERTLYFLPRE--------MKIDLNTGKETATPIT----MKD 419
Query: 440 AVSDTKNEIAKHLVDLGVSSFSMAPVKRKYAFERTDIPAGENYVVKINYLFKDTALPVDL 499
+ ++I+ + F V++ YAFE D+P Y+ ++ Y + LP +L
Sbjct: 420 VYEEFDSKIS---AKYKIMKFKSKIVEKNYAFEIPDVPEKSEYL-EVRYSAEVPQLPQNL 475
Query: 500 KGKSFCALLGARNSALELFLIKRKIKGPSWLQVSNFSTCSASQRVSWCKFEVIVDSPKDI 559
KG++F + G S+LELFL+ RKIKGP WL+V N + Q +SWCKFE + P +
Sbjct: 476 KGETFSHVFGTNTSSLELFLMNRKIKGPCWLEVKNPQLLN--QPISWCKFEAMALKPDLV 533
Query: 560 RASSPSSSKITLVNPPVVVTAINLKTTINEKQNINEIVS-ASVVSCNMVKIDTPMLASEW 618
S PP+VV + ++KT N + + +EI++ A++V N P
Sbjct: 534 NVIKDVSP------PPLVVMSFSMKTMQNVQNHQHEIIAMAALVHHNFPLDKAP------ 581
Query: 619 KRPGMLTHFTVIRKLDGNIFPMGFNTEVTDRNIKAGSNVLCVESSERALLNRLMLQLHKM 678
+P THF V+ K IFP F + +N++ V ++ER LL + ++HK+
Sbjct: 582 PKPPFQTHFCVVSKPKDCIFPCAFKEVIKKKNMEVE-----VAATERTLLGFFLAKVHKL 636
Query: 679 DSDVLVGHNISGFDLDVLLHRSQACRVPSSMWSKLGRLNRSTMPKLDRRGKTFGFGADPA 738
D D+LVGHNI GF+L+VLL R C+VP WSK+GRL RS MPKL R GFG A
Sbjct: 637 DPDILVGHNICGFELEVLLQRINECKVP--FWSKIGRLRRSNMPKLGSRS---GFGERNA 691
Query: 739 IMSCVAGRLLCDTYLCSRDLLKEVSYSLTHLAKTQLNQSRKEVAPHEVPKMFQTAKSLME 798
GR++CD + ++L+ SY L+ L + L R + + M+ L+
Sbjct: 692 ----TCGRMICDVEISVKELIHCKSYHLSELVQQILKTERIVIPTENIRNMYSEPSHLLY 747
Query: 799 LIEYGETDAWLSMELMFYLSVLPLTRQLTNLSGNLWGKTLQGARAQRVEYLLLHEFHKKK 858
L+E+ DA +++M L+VLPL Q+TN++GN+ +TL G R++R E+LLLH F++
Sbjct: 748 LLEHIWKDARFILQIMCELNVLPLALQITNIAGNIMSRTLMGGRSERNEFLLLHAFYENN 807
Query: 859 YIVPDKFSNYAKETKLTKRRVTHGVDDGNFDDADINDANYHNDASESDHKKNKKAASYAG 918
YIVPDK ++ ++ D+ D D N +KK +K A+YAG
Sbjct: 808 YIVPDK--------QIFRKPQQKPGDEDEEIDGDTNK-----------YKKGRKKAAYAG 848
Query: 919 GLVLEPKKGLYDKYILLLDFNSLYPSIIQEYNICFTTVERSSDDSF-----------PRL 967
GLVL+PK G YDK+ILLLDFNSLYPSIIQE+NICFTTV+R + ++ P L
Sbjct: 849 GLVLDPKVGFYDKFILLLDFNSLYPSIIQEFNICFTTVQRVASETLKATEDEEQEQIPEL 908
Query: 968 PSSKTT-GVLPELLKKLVKLRREKKTWMKTASGLKRQ---QLDIEQQALKLTANSMYGCL 1023
P G+LP ++KLV+ R++ K MK L Q DI Q+ALKLTANSMYGCL
Sbjct: 909 PDPNLDMGILPREIRKLVERRKQVKQLMKQQD-LNPDLVLQYDIRQKALKLTANSMYGCL 967
Query: 1024 GFSNSRFYAKPLAELITLQGREILQSTVDLVQNNLNLEVIYGDTDSIMIYSGLDDIAKAT 1083
GFS SRFYAKPLA L+T +GREIL T ++VQ +NLEVIYGDTDSIMI + ++ +
Sbjct: 968 GFSYSRFYAKPLAALVTYKGREILMHTKEMVQK-MNLEVIYGDTDSIMINTNSTNLEEVF 1026
Query: 1084 SISKKVIQEVNKKYRCLEIDLDGLYKRMLLLKKKKYAAVKVQ-FKDGTPYEVIERKGLDI 1142
+ KV EVNK Y+ LEID+DG++K +LLLKKKKYAA+ V+ DG E KGLDI
Sbjct: 1027 KLGNKVKNEVNKLYKLLEIDIDGVFKSLLLLKKKKYAALVVEPTSDGNYITKQELKGLDI 1086
Query: 1143 VRRDWSLLAKDLGDFCLTQILSGGSCEDVVESIHNSLMKVQEEMRNGQVALEKYVITKTL 1202
VRRDW LAKD G+F + QILS S + +VE+I L+++ E + NG V + ++ I K L
Sbjct: 1087 VRRDWCDLAKDTGNFVIGQILSDQSRDTIVENIQKRLIEIGENVLNGSVPVSQFEINKAL 1146
Query: 1203 TKPPEAYPDAKNQPHVLVAQRLKQQGYTSGCSVGDTIPYVICCEQGGSSGSATGIALRAR 1262
TK P+ YPD K+ PHV VA + QG GDT+ YVIC Q GS+ AT RA
Sbjct: 1147 TKDPQDYPDKKSLPHVHVALWINSQGGRK-VKAGDTVSYVIC--QDGSNLPAT---QRAY 1200
Query: 1263 HPDELKQEQGTWLIDIDYYLSQQIHPVISRLCASIQGTSPERLADCLGLDTSKFQHKSSE 1322
P++L Q+Q ID YYL+QQIHPV++R+C I G +A LGLD+++F + +
Sbjct: 1201 APEQL-QKQDNLAIDTQYYLAQQIHPVVARICEPIDGIDAVLIALWLGLDSTQF--RVHQ 1257
Query: 1323 ASDDPTSSLLFAGDDEESEKPTSSGTDESDYNFWRKL--CCPKC-----FEN---GAG-- 1370
D + L G + TDE Y K CP C ++N G+G
Sbjct: 1258 YHKDEENDALLGG--------PAQLTDEEKYKDCEKFKCLCPSCGTENIYDNVFEGSGMD 1309
Query: 1371 -------------RISAA----MIANQVKRQAEKFVLMYYRGLLMCDDETCKHTTRSVSF 1413
+ S A ++N++ + + YY G L+C++ TC++ R +
Sbjct: 1310 MEPSLNRCSNIDCKASPATFMVQLSNKLIMDIRRCIKKYYDGWLICEEPTCRNRIRRLPL 1369
Query: 1414 RLVGDSERGTVCPNYPRCNGHLNRKYTEADLYKQLSYFCHVFDTVCYIEKMEAKSRIPIE 1473
S G +CP + L +Y++ LY QL ++ ++FD C +EK+ + ++
Sbjct: 1370 HF---SRNGPLCPACMK--AVLRPEYSDKSLYTQLCFYRYIFDADCALEKLPEHEKDKLK 1424
Query: 1474 KELIKIRPIVD 1484
K+ R + D
Sbjct: 1425 KQFFTPRVLQD 1435
>ref|XP_416792.1| PREDICTED: similar to polymerase (DNA directed), alpha [Gallus
gallus]
Length = 2050
Score = 670 bits (1728), Expect = 0.0
Identities = 438/1108 (39%), Positives = 608/1108 (54%), Gaps = 145/1108 (13%)
Query: 382 VW--QGTLYQSCCVVVKNMQRCVYAIPSHPLHSTNEMIQLEKDVQESRISPADFRKKLQD 439
VW Y SCCV VKN++R VY +P EM E+ ++ + K+ D
Sbjct: 646 VWIESANTYVSCCVTVKNIERTVYLLPRE-----TEMDLSSGKETETPVTIMNVFKEFND 700
Query: 440 AVSDTKNEIAKHLVDLGVSSFSMAPVKRKYAFERTDIPAGENYV-----VKINYLFKDT- 493
+S K +I K F V++ YAFE D+PA Y+ V + L KD
Sbjct: 701 CISP-KYKIMK---------FKSKKVEKYYAFEIPDVPAKSEYLEVKYSVSMTNLMKDQN 750
Query: 494 ------------ALPVDLKGKSFCALLGARNSALELFLIKRKIKGPSWLQVSNFSTCSAS 541
LP DLKG++F G S+LEL L+ RKIKGP WL++ N ++
Sbjct: 751 LLLCLLGNAEYPRLPQDLKGETFSHAFGTNTSSLELLLMSRKIKGPCWLEIKNPQP--SN 808
Query: 542 QRVSWCKFEVIVDSPKDIRASSPSSSKITLVNPPVVVTAINLKTTINEKQNINEIVSASV 601
Q VSWCK E + P + PP+VV + ++KT N K + NEIV+ +
Sbjct: 809 QSVSWCKVEAVAMKPGLVNVVKDLPPP-----PPLVVMSFSMKTIQNPKTHQNEIVAMAA 863
Query: 602 VSCNMVKIDTPMLASEWKRPGMLTHFTVIRKLDGNIFPMGFNTEVTDRNIKAGSNVLCVE 661
+ +D +P THF + K + IFP F E+ +N K + +
Sbjct: 864 LIHQKFPLDKAP-----PQPPFQTHFCAVSKPNDCIFPYDFKEEIKKKNAK-----IEIA 913
Query: 662 SSERALLNRLMLQLHKMDSDVLVGHNISGFDLDVLLHRSQACRVPSSMWSKLGRLNRSTM 721
++ER LL + ++HK+D DV+VGHNI GFDL+VLL R C+VP WSK+GRL RS M
Sbjct: 914 ATERTLLGFFLAKIHKIDPDVVVGHNIYGFDLEVLLQRINVCKVPH--WSKIGRLRRSNM 971
Query: 722 PKLDRRGKTFGFGADPAIMSCVAGRLLCDTYLCSRDLLKEVSYSLTHLAKTQLNQSRKEV 781
PKL RG GFG A GR++CD + +++L++ SY L+ L L R +
Sbjct: 972 PKLGGRG---GFGERNA----ACGRMICDVEISAKELIRCKSYHLSELVHQILKTERVTI 1024
Query: 782 APHEVPKMFQTAKSLMELIEYGETDAWLSMELMFYLSVLPLTRQLTNLSGNLWGKTLQGA 841
P E+ ++ + L+ ++E TDA +++M L+VLPL Q+TN+SGN+ +T+ G
Sbjct: 1025 LPEEIRNLYSDSPHLLFMLENTWTDAKFILQIMCELNVLPLALQITNISGNVMSRTMMGG 1084
Query: 842 RAQRVEYLLLHEFHKKKYIVPDKFSNYAKETKLTKRRVTHGVDDGNFDDADINDANYHND 901
R++R E+LLLH F++K YIVPDK ++ K+ + VD +D D D N
Sbjct: 1085 RSERNEFLLLHAFYEKDYIVPDK--------QVFKKPLQKLVD----EDEDFEDQN---- 1128
Query: 902 ASESDHKKNKKAASYAGGLVLEPKKGLYDKYILLLDFNSLYPSIIQEYNICFTTVERSS- 960
K KK A+YAGGLVL+PK G YDK+ILLLDFNSLYPSIIQE+NICFTTV+R S
Sbjct: 1129 ----KSKIGKKKAAYAGGLVLDPKVGFYDKFILLLDFNSLYPSIIQEFNICFTTVQRLSS 1184
Query: 961 ----------DDSFPRLPS-SKTTGVLPELLKKLVKLRREKKTWMK--TASGLKRQQLDI 1007
++ P LP S G+LP+ ++KLV+ RR+ K MK + Q DI
Sbjct: 1185 EAQKRAEVEEEEEIPELPDPSLEMGILPKEIRKLVERRRQVKQLMKQPDLNPDLYLQYDI 1244
Query: 1008 EQQALKLTANSMYGCLGFSNSRFYAKPLAELITLQGREILQSTVDLVQNNLNLEVIYGDT 1067
Q+ALKLTANSMYGCLGFS SRFYAKPLA L+T +GREIL T ++VQ +NLEVIYGDT
Sbjct: 1245 RQKALKLTANSMYGCLGFSYSRFYAKPLAALVTHKGREILMHTKEMVQ-KMNLEVIYGDT 1303
Query: 1068 DSIMIYSGLDDIAKATSISKKVIQEVNKKYRCLEIDLDGLYKRMLLLKKKKYAAVKVQ-F 1126
DSIMI + ++ + + K+ EVNK Y+ LEID+DG++K +LLLKKKKYAA+ V+
Sbjct: 1304 DSIMINTNSTNLDEVFKLGNKIKSEVNKLYKLLEIDIDGVFKSLLLLKKKKYAALTVEPT 1363
Query: 1127 KDGTPYEVIERKGLDIVRRDWSLLAKDLGDFCLTQILSGGSCEDVVESIHNSLMKVQEEM 1186
DG E KGLDIVRRDW LAK+ G++ + QILS + +VE+I L+++ E +
Sbjct: 1364 GDGKYVTKQELKGLDIVRRDWCDLAKETGNYVIGQILSDQPRDIIVENIQRRLIEIGENV 1423
Query: 1187 RNGQVALEKYVITKTLTKPPEAYPDAKNQPHVLVAQRLKQQGYTSGCSVGDTIPYVICCE 1246
NGQ+ + ++ I K LTK P+ YPD K+ PHV VA + QG GDT+ Y+IC
Sbjct: 1424 INGQIPVNQFEINKALTKDPQDYPDKKSLPHVHVAMWINSQGGRK-VKAGDTVSYIIC-- 1480
Query: 1247 QGGSSGSATGIALRARHPDELKQEQGTWLIDIDYYLSQQIHPVISRLCASIQGTSPERLA 1306
Q GS+ SA + RA P++L Q+Q ID YYLSQQIHPV++R+C I+G +A
Sbjct: 1481 QDGSNLSA---SQRAYAPEQL-QKQDNLTIDTQYYLSQQIHPVVARICEPIEGIDSVLIA 1536
Query: 1307 DCLGLDTSKFQHKSSEASDDPTSSLLFAGDDEESEKPTSSGTDESDYNFWR--KLCCPKC 1364
LGLD S+F+ D+ +L+ + TDE Y K CC KC
Sbjct: 1537 TWLGLDPSQFRVHHHYHKDEENDALVGG---------PAQLTDEEKYRDCERFKFCCLKC 1587
Query: 1365 -----FEN---GAGRISAAMIANQVKRQAE-------------------KFVLMYYRGLL 1397
++N +GR + K + E +++ YY G L
Sbjct: 1588 GTENIYDNVFDCSGRFIEPSLQRCSKSECEEPPFNHVVQMNNKLLLDIRRYLKKYYNGWL 1647
Query: 1398 MCDDETCKHTTRSVSFRLVGDSERGTVC 1425
+C+D TC++ TR + S G +C
Sbjct: 1648 ICEDPTCQNRTRRLPLSF---SRSGPIC 1672
>dbj|BAD92008.1| DNA polymerase alpha catalytic subunit [Trachemys scripta]
Length = 1441
Score = 667 bits (1722), Expect = 0.0
Identities = 428/1121 (38%), Positives = 622/1121 (55%), Gaps = 129/1121 (11%)
Query: 388 YQSCCVVVKNMQRCVYAIPSHPLHSTNEMIQLEKDVQESRISPADFRKKLQDAVSDTKNE 447
Y SCCV VKN++R +Y +P +M E+ ++ + ++ D ++
Sbjct: 343 YVSCCVTVKNIERIIYLLPREM-----QMDLTSGKETENPVTMMNIYQEFNDQIA----- 392
Query: 448 IAKHLVDLGVSSFSMAPVKRKYAFERTDIPAGENYVVKINYLFKDTALPVDLKGKSFCAL 507
V + F V++ YAFE D+PA +Y+ ++ Y + LP DLKG++F +
Sbjct: 393 -----VKYKIMKFRSKKVEKNYAFEIPDVPAKSDYL-EVRYSAEFPRLPQDLKGETFSHV 446
Query: 508 LGARNSALELFLIKRKIKGPSWLQVSNFSTCSASQRVSWCKFEVIVDSPKDIRASSPSSS 567
G S+LEL L+ RKIKGPSWL++ N S VSWCK E P +
Sbjct: 447 FGTNTSSLELLLMSRKIKGPSWLEIKNPQPLS--HPVSWCKVEATALKPDLVNIVKD--- 501
Query: 568 KITLVNPPVVVTAINLKTTINEKQNINEIVSASVVSCNMVKIDTPMLASEWKRPGMLTHF 627
L PP+V+ +++++T N K + +E+++ + + +D +P THF
Sbjct: 502 ---LPPPPLVIMSLSMRTIQNVKTHQHEVMAVAALVHQRFCLDKAP-----PQPPFQTHF 553
Query: 628 TVIRKLDGNIFPMGFNTEVTDRNIKAGSNVLCVESSERALLNRLMLQLHKMDSDVLVGHN 687
VI K + IFP F + +N SNV + ++ER LL + ++HK+D D++VGHN
Sbjct: 554 CVISKPNDCIFPYDFKEIIKSKN----SNVE-IAATERTLLGFFLAKVHKIDPDIIVGHN 608
Query: 688 ISGFDLDVLLHRSQACRVPSSMWSKLGRLNRSTMPKLDRRGKTFGFGADPAIMSCVAGRL 747
I GFDL+VLL R +VP WSK+GRL RS MPKL RG GF A + GR+
Sbjct: 609 IYGFDLEVLLQRINVSKVPH--WSKIGRLRRSIMPKLGGRG---GF----AERNAACGRM 659
Query: 748 LCDTYLCSRDLLKEVSYSLTHLAKTQLNQSRKEVAPHEVPKMFQTAKSLMELIEYGETDA 807
+CD + +++L++ SY L+ L L R + P E+ M+ + L+ ++E TDA
Sbjct: 660 ICDVEISAKELIRCKSYHLSELVHQILKTERITIPPEEIRNMYSDSSHLLYMLENTWTDA 719
Query: 808 WLSMELMFYLSVLPLTRQLTNLSGNLWGKTLQGARAQRVEYLLLHEFHKKKYIVPDKFSN 867
+++M L+VLPL Q+TN+SGN+ +T+ G R++R E+LLLH F+++ YIVPDK
Sbjct: 720 RFILQIMCELNVLPLALQITNISGNVMSRTMMGGRSERNEFLLLHAFYERDYIVPDKQVF 779
Query: 868 YAKETKLTKRRVTHGVDDGNFDDADINDANYHNDASESDHKKNKKAASYAGGLVLEPKKG 927
+ KL GV+D N K +K A+YAGGLVL+PK G
Sbjct: 780 KKPQQKLVDE--DEGVEDQN------------------KSKIGRKKAAYAGGLVLDPKVG 819
Query: 928 LYDKYILLLDFNSLYPSIIQEYNICFTTVERSSDDS-----------FPRLPS-SKTTGV 975
YD +ILLLDFNSLYPSIIQE+NICFTTV+R S D+ P LP S G+
Sbjct: 820 FYDTFILLLDFNSLYPSIIQEFNICFTTVQRESSDAQKRAEDGVQEEIPELPDPSLEMGI 879
Query: 976 LPELLKKLVKLRREKKTWMK--TASGLKRQQLDIEQQALKLTANSMYGCLGFSNSRFYAK 1033
LP+ ++KLV+ RR+ K MK + Q DI Q+ALKLTANSMYGCLGFS SRFYAK
Sbjct: 880 LPKEIRKLVERRRQVKQLMKQPDLNPDLYLQYDIRQKALKLTANSMYGCLGFSYSRFYAK 939
Query: 1034 PLAELITLQGREILQSTVDLVQNNLNLEVIYGDTDSIMIYSGLDDIAKATSISKKVIQEV 1093
PLA L+T +GREIL T ++VQ +NLEVIYGDTDSIMI + ++ + + K+ EV
Sbjct: 940 PLAALVTHKGREILMHTKEMVQ-KMNLEVIYGDTDSIMINTNSTNLEEVFKLGNKIKSEV 998
Query: 1094 NKKYRCLEIDLDGLYKRMLLLKKKKYAAVKVQ-FKDGTPYEVIERKGLDIVRRDWSLLAK 1152
NK Y+ LEID+DG++K +LLLKKKKYAA+ V+ DG E KGLDIVRRDW LAK
Sbjct: 999 NKLYKLLEIDIDGVFKSLLLLKKKKYAALTVEPTGDGKYVTKQELKGLDIVRRDWCDLAK 1058
Query: 1153 DLGDFCLTQILSGGSCEDVVESIHNSLMKVQEEMRNGQVALEKYVITKTLTKPPEAYPDA 1212
+ G++ + QILS S + +VE+I L+++ E + NG+V + ++ I K LTK P+ YPD
Sbjct: 1059 ETGNYVIGQILSDQSRDTIVENIQRRLIEIGENVINGRVPISQFEINKALTKDPQDYPDK 1118
Query: 1213 KNQPHVLVAQRLKQQGYTSGCSVGDTIPYVICCEQGGSSGSATGIALRARHPDELKQEQG 1272
K+ PHV VA + Q GDT+ YVIC Q GS+ SA + RA P++L Q+Q
Sbjct: 1119 KSLPHVHVAMWINSQEGRK-VKAGDTVSYVIC--QDGSNLSA---SQRAYAPEQL-QKQE 1171
Query: 1273 TWLIDIDYYLSQQIHPVISRLCASIQGTSPERLADCLGLDTSKFQHKSSEASDDPTSSLL 1332
+D YYLSQQIHPV++R+C I G +A LGLD S+F+ D+ +LL
Sbjct: 1172 NLTVDTQYYLSQQIHPVVARICEPIDGIDSVLIATWLGLDPSQFKIHHHYHKDEENDALL 1231
Query: 1333 FAGDDEESEKPTSSGTDESDYNFWR--KLCCPKC-----FEN---GAGRISAAMIANQVK 1382
+ TDE Y K CP+C ++N G+G++ + K
Sbjct: 1232 GG---------PAQLTDEEKYRDCERFKFSCPRCGTENIYDNVFDGSGKLMEPSLQQCSK 1282
Query: 1383 RQAE-------------------KFVLMYYRGLLMCDDETCKHTTRSVSFRLVGDSERGT 1423
++ + +++ YY L+C++ TC++ TR + S+ G
Sbjct: 1283 KECDESPFNYTIQMNNKLLLDIRRYLKSYYNSWLICEEPTCQNRTRRLPLSF---SQNGA 1339
Query: 1424 VCPNYPRCNGHLNRKYTEADLYKQLSYFCHVFDTVCYIEKM 1464
+C + L +Y++ LY QL ++ ++FD ++K+
Sbjct: 1340 LCQACKK--AILRPEYSDKALYTQLCFYRYIFDVDYAMDKV 1378
>dbj|BAC76767.1| DNA polymerase alpha catalytic subunit [Coprinopsis cinerea]
Length = 1426
Score = 662 bits (1709), Expect = 0.0
Identities = 427/1149 (37%), Positives = 629/1149 (54%), Gaps = 113/1149 (9%)
Query: 390 SCCVVVKNMQRCVYAIPSHPLHSTNEMIQLEKD---VQESRISPADFRKKLQDAVSDTKN 446
SCCV + ++R +YA+P + I ++D V E+ P D D +
Sbjct: 353 SCCVTIDGLERNLYALPRE------KRIDFDEDTGEVTETDEIPTD---------EDVLD 397
Query: 447 EIAKHLVDLGVSSFSMAPVKRKYAFERTDIPAGENYVVKINYLFKDTALPVDLKGKSFCA 506
+ + ++ + S+ VKR YAF D+P GE +KI Y + P+ + +
Sbjct: 398 DFEQLRQNMKIKSYKTRFVKRNYAFGEKDVPRGETGWLKIVYHSLNPD-PMGVWSPNISH 456
Query: 507 LLGARNSALELFLIKRKIKGPSWLQVSNFSTCSASQRVSWCKFEVIVDSPKDIRASSPSS 566
+ G SA E+F++KRKI GP WL++ N + VSWC+FE V PKD+ S S
Sbjct: 457 IFGTNTSAFEIFVLKRKIMGPCWLEIKN--PVVEFKGVSWCRFEASVADPKDVSPMSESL 514
Query: 567 SKITLVNPPVVVTAINLKTTINEKQNINEIVSASVVSCNMVKIDTPMLASEWKRPGMLTH 626
+ V PP V +++++T +N +N E+V AS + + + ID A + P +
Sbjct: 515 DQAKEV-PPFTVMSLSVRTVVNHHENKREVVCASTRTWHNISIDDG--APPEQLPCSVQT 571
Query: 627 FTVIRKLDGNIFPMGFNTEVTDRNIKAGSNVLCVESSERALLNRLMLQLHKMDSDVLVGH 686
F IR LD FP F +E + S E S L+ L+ ++K D D+++GH
Sbjct: 572 F--IRPLDR--FPPNFESETKKKTRGRFSPRRTSECS----LSLLLAAINKSDPDIIIGH 623
Query: 687 NISGFDLDVLLHRSQACRVPSSMWSKLGRLNRSTMPKLDRRGKTFGFGADPAIMSCVAGR 746
G LDVLLHR + +V WS+LGR RS P + ++G F + GR
Sbjct: 624 EFLGVSLDVLLHRMKDLKVDH--WSRLGRFRRSKWPNIGKQGTNVRF---------LNGR 672
Query: 747 LLCDTYL-CSRDLLKEVSYSLTHLAKTQLNQSRKEVAPHEVPKMFQTAKS----LMELIE 801
L CD ++ ++ ++SLT + T L R+++ P + + S +M ++
Sbjct: 673 LTCDLASDAAKSMISSTTWSLTEMCSTHLGLERQDIDPDDTANYLDGSLSGPGKMMTFVQ 732
Query: 802 YGETDAWLSMELMFYLSVLPLTRQLTNLSGNLWGKTLQGARAQRVEYLLLHEFHKKKYIV 861
+ E DA M + + +LPLTRQLTNL+GN W KTL G RA+R EY+LLHEFH+ KYI
Sbjct: 733 HCEMDAHYQMAIATKVQILPLTRQLTNLAGNAWNKTLNGGRAERNEYILLHEFHRLKYIC 792
Query: 862 PDKFSNYAKETKLTKRRVTHGVDDGNFDDADINDANYHNDASESDHKKNKKAASYAGGLV 921
PDK Y K+T A+ DA +S K++K Y GGLV
Sbjct: 793 PDK--TYGKKT------------------VPKETADEEGDAPKSKAKRDK----YKGGLV 828
Query: 922 LEPKKGLYDKYILLLDFNSLYPSIIQEYNICFTTVE-----RSSDDSFPRLPSSKTTGVL 976
EPK+GL+D YIL++DFNSLYPSIIQEYNI FTTV+ + ++ P PS K GVL
Sbjct: 829 FEPKRGLWDSYILVMDFNSLYPSIIQEYNIDFTTVDPPEVDENGEEKIPDPPSDKDKGVL 888
Query: 977 PELLKKLVKLRREKKTWMK--TASGLKRQQLDIEQQALKLTANSMYGCLGFSNSRFYAKP 1034
P L+ LV RR+ K+ MK TA+ K Q DI+QQALKLTANSMYGCLGF SRFYA+P
Sbjct: 889 PRLIATLVNRRRQVKSLMKDRTATPAKLLQYDIKQQALKLTANSMYGCLGFEYSRFYARP 948
Query: 1035 LAELITLQGREILQSTVDLVQNNLNLEVIYGDTDSIMIYSGLDDIAKATSISKKVIQEVN 1094
LA L T +GREIL T +L ++ LNL+VIYGDTDS+ + SG++D A+A S + VN
Sbjct: 949 LAALTTFKGREILTRTRELAES-LNLDVIYGDTDSVFVNSGVNDFAEALKTSAIFKKAVN 1007
Query: 1095 KKYRCLEIDLDGLYKRMLLLKKKKYAAVKVQFKDGTPYEVIERKGLDIVRRDWSLLAKDL 1154
+Y LEIDLD +++R+LLL+KKKYAA+KV+ T EV KGLD+ RR++ L+K++
Sbjct: 1008 DQYNLLEIDLDCVFQRLLLLQKKKYAALKVEDGSRTSVEV---KGLDMKRREYCALSKEV 1064
Query: 1155 GDFCLTQILSGGSCEDVVESIHNSLMKVQEEMRNGQVALEKYVITKTLTKPPEAYPDAKN 1214
+ L +ILSG S EDVVE+IH L + + +R+GQV LE +++ K L K PE YPDAK+
Sbjct: 1065 SQYVLARILSGDSTEDVVETIHEYLGTMSQNVRSGQVKLEDFIVFKRLGKNPEDYPDAKS 1124
Query: 1215 QPHVLVAQRLKQQGYTSGCSVGDTIPYVICCEQGGSSGSATGIALRARHPDELKQEQGTW 1274
QPHV VA R+K +G ++ GD IPY+ C +G S T A RARHPDE+++ G
Sbjct: 1125 QPHVQVALRMKAKGQSA--RGGDVIPYIFCLGEGEESARTTQ-ADRARHPDEVRRGAGVV 1181
Query: 1275 LIDIDYYLSQQIHPVISRLCASIQGTSPERLADCLGLDTSKFQHKSSE------ASDDPT 1328
ID ++YL+ Q+ P I RLC +I+GT RLA+CLGLD ++++ ++ + D
Sbjct: 1182 KIDYEWYLAHQVLPPIERLCDAIEGTDRARLAECLGLDPNRYRTTTASDEKFFMSLDSQM 1241
Query: 1329 SSLLFAGDDEESEKPTSSGTDESDYNFWRKLCCPKCFENGAGRISA------AMIANQVK 1382
S D + E S ++ + P +G +S + Q++
Sbjct: 1242 SDAERFKDADPFEVRCKSCQGKTKFPLLHDRTIPLVRASGVTCLSCDKPIAGVNLQLQLE 1301
Query: 1383 RQAEKFVLMYYRGLLMCDDETCKHTTRSVSFRLVGDSERGTVCPNYPRCNGHLNRKYTEA 1442
Q + YY G +CD++TCK+ TR++ G C P C G ++ +Y++
Sbjct: 1302 VQIRAHISKYYEGWTVCDEQTCKNRTRAMGV-------YGKRCLK-PGCRGRVSFEYSDT 1353
Query: 1443 DLYKQLSYFCHVFDTVCYIEKMEAKSRIPIEKELIKI----RPIVDLAASTIQKIRDRCA 1498
LY QL Y+ ++FD + ++A E+E++ + +++ + ++K ++C
Sbjct: 1354 KLYNQLRYYKYLFDRE---KALKAARGTGSEEEVLAVVGSQATLLNNLSDVVEKYLNQCG 1410
Query: 1499 FGWVKLQDL 1507
WV L +
Sbjct: 1411 RRWVDLNSI 1419
>gb|AAT68051.1| DNA polymerase alpha [Danio rerio]
Length = 1389
Score = 661 bits (1705), Expect = 0.0
Identities = 435/1113 (39%), Positives = 612/1113 (54%), Gaps = 124/1113 (11%)
Query: 390 SCCVVVKNMQRCVYAIPSHPLHSTNEMIQLEKDVQESRISPADFRKKLQDAVSDTKNEIA 449
SCCV VKN++R +Y +P +E +++ A K + + D E
Sbjct: 360 SCCVAVKNIERTMYLLP-----------------REHKVNLATGEKGVAVGMMDVYKEFN 402
Query: 450 KHLVDLGVSSFSMAPVKRKYAFERTDIPAGENYVVKINYLFKDTALPVDLKGKSFCALLG 509
+ + F PV + YAFE DIP+ Y+ ++ Y + +LP DLKG +F + G
Sbjct: 403 EISEKFKIMKFKSKPVTKNYAFEIPDIPSQSEYL-EVKYSAEIPSLPSDLKGTTFSHVFG 461
Query: 510 ARNSALELFLIKRKIKGPSWLQVSNFSTCSASQRVSWCKFEVIVDSPKDIRASSPSSSKI 569
S+LE FL+ RKI+GP WL V+ ++Q +SWCK E + I S
Sbjct: 462 TNTSSLEHFLLNRKIRGPCWLDVTTPQL--SNQPISWCKVEAVAQKSDLISVVKDLSP-- 517
Query: 570 TLVNPPVVVTAINLKTTINEKQNINEIVSASVVSCNMVKIDTPMLASEWKRPGMLTHFTV 629
PP+VV +I+LKT N K + NEIVS + + + +D RP THF
Sbjct: 518 ----PPLVVMSISLKTVQNPKTHQNEIVSIAALVHHTFPLDKAP-----PRPPFQTHFCE 568
Query: 630 IRKLDGNIFPMGFNTEVTDRNIKAGSNV-LCVESSERALLNRLMLQLHKMDSDVLVGHNI 688
+ P+ N ++ AGS++ + ERALL ++HK+D DVL+GH+I
Sbjct: 569 ------SDTPIKNNFQIAS----AGSSLKIRTLFYERALLGFFPFKMHKIDPDVLLGHDI 618
Query: 689 SGFDLDVLLHRSQACRVPSSMWSKLGRLNRSTMPKLDRRGKTFGFGADPAIMSCVAGRLL 748
GFDL+VLL R C+VP WSK+GRL R+ MPKL R GF A S GRL+
Sbjct: 619 FGFDLEVLLQRINVCKVPH--WSKIGRLRRANMPKLGGRS---GF----AEKSATCGRLV 669
Query: 749 CDTYLCSRDLLKEVSYSLTHLAKTQLNQSRKEVAPHEVPKMFQTAKS-LMELIEYGETDA 807
CD + +++L++ SY+LT L L R V P + Q + L+ L+E DA
Sbjct: 670 CDIEISAKELIRCKSYNLTELVSQILKAERPVVPPENISTFLQVDSTHLLYLLELTWMDA 729
Query: 808 WLSMELMFYLSVLPLTRQLTNLSGNLWGKTLQGARAQRVEYLLLHEFHKKKYIVPDKFSN 867
L +++M L+VLPL Q+TN++GN+ +TL G R++R EYLLLH FH++ +IVPDK
Sbjct: 730 KLILQIMCELNVLPLALQITNIAGNVMSRTLMGGRSERNEYLLLHAFHERDFIVPDK--- 786
Query: 868 YAKETKLTKRRVTHGVDDGNFDDADINDANYHNDASESDHKKNKKAASYAGGLVLEPKKG 927
K + G D+ D+ + K +K A+YAGGLVL+PK G
Sbjct: 787 ----QFFKKAQQDLGEDE-------------EGDSGKGKSNKTRKKAAYAGGLVLDPKVG 829
Query: 928 LYDKYILLLDFNSLYPSIIQEYNICFTTVERSS----------DDSFPRLPS-SKTTGVL 976
YDK+ILLLDFNSLYPSIIQE+NICFTTVER + +D P LP S G+L
Sbjct: 830 FYDKFILLLDFNSLYPSIIQEFNICFTTVERGATNTRKKTEEDEDEIPELPDQSLEMGIL 889
Query: 977 PELLKKLVKLRREKKTWMKTASGLKRQ---QLDIEQQALKLTANSMYGCLGFSNSRFYAK 1033
P+ ++KLV+ RR+ K MK L Q DI Q+ALKLTANSMYGCLGFS SRFYAK
Sbjct: 890 PKEIRKLVERRRQVKQLMKEPD-LNPDLYLQYDIRQKALKLTANSMYGCLGFSFSRFYAK 948
Query: 1034 PLAELITLQGREILQSTVDLVQNNLNLEVIYGDTDSIMIYSGLDDIAKATSISKKVIQEV 1093
PLA L+T +GREIL T ++VQ +NLEVIYGDTDSIMI + ++ + + KV EV
Sbjct: 949 PLAALVTHKGREILMHTKEMVQR-MNLEVIYGDTDSIMINTNSTNLEEVFKLGNKVKSEV 1007
Query: 1094 NKKYRCLEIDLDGLYKRMLLLKKKKYAAVKVQFK-DGTPYEVIERKGLDIVRRDWSLLAK 1152
NK Y+ LEID+DG++K +LLLKKKKYAA+ V+ + DG E KGLDIVRRDW LAK
Sbjct: 1008 NKLYKLLEIDIDGVFKSLLLLKKKKYAALMVEPQGDGKYTTKQELKGLDIVRRDWCDLAK 1067
Query: 1153 DLGDFCLTQILSGGSCEDVVESIHNSLMKVQEEMRNGQVALEKYVITKTLTKPPEAYPDA 1212
+ G++ + QILS + + ++E+I L+++ E++ NG + L + I K+LTK P+ YPD
Sbjct: 1068 ECGNYVIGQILSDQNRDTIIENIQKHLIEIGEKVANGNIPLNMFEIHKSLTKEPQDYPDK 1127
Query: 1213 KNQPHVLVAQRLKQQGYTSGCSVGDTIPYVICCEQGGSSGSATGIALRARHPDELKQEQG 1272
K+ PHV VA + QG GDT+ YVIC GS + RA ++L+++ G
Sbjct: 1128 KSLPHVHVALWINSQG-GKKVKAGDTVSYVIC-----QDGSNLAASQRAYTLEQLQKQPG 1181
Query: 1273 TWLIDIDYYLSQQIHPVISRLCASIQGTSPERLADCLGLDTSKF---QHKSSEASDDPTS 1329
L D YYLSQQ+HPV+ R+C I+G +A LGLD S F Q + + +DD
Sbjct: 1182 LNL-DTQYYLSQQVHPVVGRICEPIEGIDAVLIATWLGLDPSHFRAQQQQREDEADDFLG 1240
Query: 1330 SLLFAGDDE---ESEKPTSSGTDESDYNFW--------------RKLCC-PKCFENGAGR 1371
+ D+E + E+ T + D N + K CC C G+
Sbjct: 1241 APAQLTDEERYRDCERFTFTCPDCGTENIYDNVFEGTGSTLQLSLKSCCHVPC--GGSPM 1298
Query: 1372 ISAAMIANQVKRQAEKFVLMYYRGLLMCDDETCKHTTRSVSFRLVGDSERGTVCPNYPRC 1431
I N+++ + + YY G L+C+D+ C++ R + + S G +CP R
Sbjct: 1299 DHQVQIGNKLQLDIRRHIRRYYSGWLLCEDQACRNRIRRLP---IAFSRSGPICPACLRS 1355
Query: 1432 NGHLNRKYTEADLYKQLSYFCHVFDTVCYIEKM 1464
L +Y+E LY QLS++ ++FD I K+
Sbjct: 1356 T--LKPEYSEKALYNQLSFYRYIFDWEYAINKV 1386
>gb|AAP45775.1| DNA polymerase catalytic subunit alpha [Stylonychia lemnae]
Length = 1514
Score = 650 bits (1676), Expect = 0.0
Identities = 412/1165 (35%), Positives = 620/1165 (52%), Gaps = 132/1165 (11%)
Query: 377 GYSLFVWQGTLYQ-------SCCVVVKNMQRCVYAIPSHPLHSTNEMIQLEKDVQESR-- 427
G LF++ G +YQ SC + V MQR +YA+P + E++ Q R
Sbjct: 377 GADLFIF-GKIYQPEINQYVSCSMKVNGMQREIYALPKMQKGKARGTLTREEENQLVRGV 435
Query: 428 -ISPADFRKKLQDAVSDTKNEIAKHLVDLGVSSFSMAPVKRKYAFERTDIPAGENYVVKI 486
+ D RKK G++ + PV RKYAFE I GE+ +KI
Sbjct: 436 QLELEDIRKKRFQ----------------GITKWRCKPVTRKYAFEMP-IQHGEHLFLKI 478
Query: 487 NYLFKDTALPVDLKGKSFCALLGARNSALELFLIKRKIKGPSWLQVSNFSTCSASQRVSW 546
Y LP ++G +F L G+ S LELF++KRKIKGP W+ + N + ++ +W
Sbjct: 479 KYDATFIPLPSTVQGNTFECLFGSNQSMLELFILKRKIKGPCWMTIKNPKKVTDFKK-TW 537
Query: 547 CKFEVIVDSPKDIRASSPSSSKITLVNPPVVVTAINLKTTINEKQNINEIVSASVVSCNM 606
C+ E+ +D+PK+ + +K + PP+ KT + N NEI S + N
Sbjct: 538 CRQEIEIDNPKNAEVTLDDLNKTDI--PPLTSLTFAFKTA-RSQNNTNEIAMISCLVHNN 594
Query: 607 VKIDTPMLASEWKRPGMLTHFTVIRKLDGNIFPMGFNTEVTDRNIKAGSNVLCVESSERA 666
V + P +++ FT++RKLDG P F D+ ++ + ++ER
Sbjct: 595 VNQEGPSQTDKFQT------FTLVRKLDGKPMPFDF-----DQKLRQKKENIQYFTNERQ 643
Query: 667 LLNRLMLQLHKMDSDVLVGHNISGFDLDVLLHRSQACRVPSSMWSKLGRLNRSTMP--KL 724
+++ + ++ ++D D++V HN+ G D+LL R Q ++ + WS++GR + +P K
Sbjct: 644 MIDLFVTRIFQIDPDLIVAHNLCGGIFDLLLARIQILKI--NHWSRIGRFKKGNIPTKKF 701
Query: 725 DRRGKTFGFGADPAIMSCVAGRLLCDTYLCSRDLLKEVSYSLTHLAKTQLNQSRKEVAPH 784
D G +G G+ GRLL DT+L +++L++E +Y LTHL K QL + R++
Sbjct: 702 DTGGANYG-GSQWIPRQVTCGRLLVDTFLSAKELIRETNYDLTHLTKVQLKKDRQDFDDD 760
Query: 785 EVPKMFQTAKSLMELIEYGETDAWLSMELMFYLSVLPLTRQLTNLSGNLWGKTLQGARAQ 844
+P+ + ++ + +LIE+ E D++ + LM +LS++PLT+QLTN++GNLW ++LQ ARA+
Sbjct: 761 LLPQFYLASERIFQLIEHSEKDSYYTFMLMLHLSIIPLTKQLTNIAGNLWFRSLQNARAE 820
Query: 845 RVEYLLLHEFHKKKYIVPDKFSNYAKETKLTKRRVTHGVDDGNFDDADINDANYHNDASE 904
R E LLLHEF KKK+I+PDK AK+ + + D ND
Sbjct: 821 RNEMLLLHEFKKKKFILPDKKPPNAKDLRR----------------GFMGDEYEENDTKG 864
Query: 905 SDHKKNK-KAASYAGGLVLEPKKGLYDKYILLLDFNSLYPSIIQEYNICFTTVERS---- 959
K K K A YAGGLV+EPK G YD ILLLDFNSLYPSIIQEYN+CFTTV R
Sbjct: 865 GGKKGGKRKKAKYAGGLVIEPKAGFYDNIILLLDFNSLYPSIIQEYNLCFTTVNRRPTKN 924
Query: 960 ---------------------SDDSFPRLPSSKTTGVLPELLKKLVKLRREKKTWMKTAS 998
D P + VLP +L+ LV+ R+ K MK
Sbjct: 925 YDGSELKNQFKSADNAEGDEVEDVDLPDKNVNIXDAVLPNVLRDLVQKRKAVKEKMKNEK 984
Query: 999 G-LKRQQLDIEQQALKLTANSMYGCLGFSNSRFYAKPLAELITLQGREILQSTVDLVQNN 1057
+K QQL+I Q+A+KLTANSMYGCLGFS+SRF+A +A LIT GRE L T D+ +N
Sbjct: 985 DQVKLQQLEIRQKAIKLTANSMYGCLGFSSSRFHASAIAALITKTGRETLLRTKDIAENK 1044
Query: 1058 LNLEVIYGDTDSIMIYSGLDDIAKATSISKKVIQEVNKKYRCLEIDLDGLYKRMLLLKKK 1117
L V+YGDTDSIMI +G + + ++ + KK+ EVN Y+CLEI++DG++K +LLLKKK
Sbjct: 1045 LGFNVVYGDTDSIMINTGTNQLQQSLEMGKKLKVEVNCLYKCLEIEIDGVFKSLLLLKKK 1104
Query: 1118 KYAAVKVQFKDGTPYEVI-ERKGLDIVRRDWSLLAKDLGDFCLTQILSGGSCEDVVESIH 1176
KYAA++ + +VI E KGLD+VRRDW L+K +G++ L+QILSG EDVV +++
Sbjct: 1105 KYAALRYEGVGSNEVKVIQEMKGLDMVRRDWCPLSKSIGNYVLSQILSGKQREDVVFNLN 1164
Query: 1177 NSLMKVQEEMRNGQVALEKYVITKTLTKPPEAYPDAKNQPHVLVAQRLKQQGYTSGCSVG 1236
L + E+M++ ++ L++++ITK LT+ Y D K QPHV VAQRLK QG + V
Sbjct: 1165 EYLSDIGEKMKSNRITLDQFIITKQLTRAISEYSDIKGQPHVAVAQRLKNQGKSEADLVN 1224
Query: 1237 DTIPYVICCEQGGSSGSATGIALRARHPDELKQEQGTWLIDIDYYLSQQIHPVISRLCAS 1296
+ IPYVI + ++ S ++ +A HPDEL +G +DID+Y++ QI P I+RL
Sbjct: 1225 NFIPYVIGAQAFDTAKSNPQLSDKAYHPDELLSSKGKITLDIDWYITTQILPPITRLIEH 1284
Query: 1297 IQGTSPERLADCLGLDTSKFQHKSSEASDDPTSSLLFAGDDEES-EKPTSSGTDESDYNF 1355
I G + E +A CLG+D K+++ S + + D GDD S + P E
Sbjct: 1285 IDGINIEFVAQCLGVDPKKYKYHSEKKNTDE------IGDDGGSIQNPILQTETEKSLKH 1338
Query: 1356 WR----KLCCPKCFEN--------------------GAGRISAAMIANQVKRQAEKFVLM 1391
K+ CP C N +I + N+V ++ + +
Sbjct: 1339 RSIAELKVKCPSCTHNYDFPGIYQEGKDVSGLICTKCNAKIPEKYVMNRVNLFLKQLLAL 1398
Query: 1392 YYRGLLMCDDETCKHTTRSVSFRLVGDSERGTVCPNYPRCNGHLNRKYTEADLYKQLSYF 1451
YY+G C + +CK TR + + C N C G + +Y+E L Y
Sbjct: 1399 YYQGKYECQEPSCKSMTRQLLYH--------NKCVNL-TCKGKMVPEYSEHQTNDTLRYL 1449
Query: 1452 CHVFDTVCYIEKMEAKSRIPIEKEL 1476
+F+ ++ + + +E ++
Sbjct: 1450 QGLFNIKKHLHENSKNDSLKVETDI 1474
>gb|AAP45773.1| DNA polymerase catalytic subunit alpha [Stylonychia lemnae]
Length = 1514
Score = 649 bits (1674), Expect = 0.0
Identities = 412/1165 (35%), Positives = 621/1165 (52%), Gaps = 132/1165 (11%)
Query: 377 GYSLFVWQGTLYQ-------SCCVVVKNMQRCVYAIPSHPLHSTNEMIQLEKDVQESR-- 427
G LF++ G +YQ SC + V MQR +YA+P + E++ Q R
Sbjct: 377 GADLFIF-GKIYQPEINQYVSCSMKVNGMQREIYALPKMQKGKARGTLTREEENQLVRGV 435
Query: 428 -ISPADFRKKLQDAVSDTKNEIAKHLVDLGVSSFSMAPVKRKYAFERTDIPAGENYVVKI 486
+ D RKK G++ + PV RKYAFE I GE+ +KI
Sbjct: 436 QLELEDIRKKRFQ----------------GITKWRCKPVTRKYAFEMP-IXHGEHLFLKI 478
Query: 487 NYLFKDTALPVDLKGKSFCALLGARNSALELFLIKRKIKGPSWLQVSNFSTCSASQRVSW 546
Y LP ++G +F L G+ S LELF++KRKIKGP W+ + N + ++ +W
Sbjct: 479 KYDATFIPLPSTVQGNTFECLFGSNQSMLELFILKRKIKGPCWMTIKNPKKVTDFKK-TW 537
Query: 547 CKFEVIVDSPKDIRASSPSSSKITLVNPPVVVTAINLKTTINEKQNINEIVSASVVSCNM 606
C+ E+ +D+PK+ + +K + PP+ KT + N NEI S + N
Sbjct: 538 CRQEIEIDNPKNAEVTLDDLNKTDI--PPLTSLTFAFKTA-RSQNNTNEIAMISCLVHNN 594
Query: 607 VKIDTPMLASEWKRPGMLTHFTVIRKLDGNIFPMGFNTEVTDRNIKAGSNVLCVESSERA 666
V + P +++ FT++RKLDG P F D+ ++ + ++ER
Sbjct: 595 VNQEGPSQTDKFQT------FTLVRKLDGKPMPFDF-----DQKLRQKKENIQYFTNERQ 643
Query: 667 LLNRLMLQLHKMDSDVLVGHNISGFDLDVLLHRSQACRVPSSMWSKLGRLNRSTMP--KL 724
+++ + ++ ++D D++V HN+ G D+LL R Q ++ + WS++GR + +P K
Sbjct: 644 MIDLFVTRIFQIDPDLIVAHNLCGGIFDLLLARIQILKI--NHWSRIGRFKKGNIPTKKF 701
Query: 725 DRRGKTFGFGADPAIMSCVAGRLLCDTYLCSRDLLKEVSYSLTHLAKTQLNQSRKEVAPH 784
D G +G G+ GRLL DT+L +++L++E +Y LTHL K QL + R++
Sbjct: 702 DTGGANYG-GSQWIPRQVTCGRLLVDTFLSAKELIRETNYDLTHLTKVQLKKDRQDFDDD 760
Query: 785 EVPKMFQTAKSLMELIEYGETDAWLSMELMFYLSVLPLTRQLTNLSGNLWGKTLQGARAQ 844
+P+ + ++ + +LIE+ E D++ + LM +LS++PLT+QLTN++GNLW ++LQ ARA+
Sbjct: 761 LLPQFYLASERIFQLIEHSEKDSYYTFMLMLHLSIIPLTKQLTNIAGNLWFRSLQNARAE 820
Query: 845 RVEYLLLHEFHKKKYIVPDKFSNYAKETKLTKRRVTHGVDDGNFDDADINDANYHNDASE 904
R E LLLHEF KKK+I+PDK AK+ + + D ND
Sbjct: 821 RNEMLLLHEFKKKKFILPDKKPPNAKDLRR----------------GFMGDEYEENDTKG 864
Query: 905 SDHKKNK-KAASYAGGLVLEPKKGLYDKYILLLDFNSLYPSIIQEYNICFTTVERSSDDS 963
K K K A YAGGLV+EPK G YD ILLLDFNSLYPSIIQEYN+CFTTV R +
Sbjct: 865 GGKKGGKRKKAKYAGGLVIEPKAGFYDNIILLLDFNSLYPSIIQEYNLCFTTVNRRPTKN 924
Query: 964 FPR----------------------LPSSKTT---GVLPELLKKLVKLRREKKTWMKTAS 998
+ LP VLP +L+ LV+ R+ K MK
Sbjct: 925 YDGSELKNQFKSADNAEGDEVEDVDLPDKNVNIKDAVLPNVLRDLVQKRKAVKEKMKNEK 984
Query: 999 G-LKRQQLDIEQQALKLTANSMYGCLGFSNSRFYAKPLAELITLQGREILQSTVDLVQNN 1057
+K QQL+I Q+A+KLTANSMYGCLGFS+SRF+A +A LIT GRE L T D+ +N
Sbjct: 985 DQVKLQQLEIRQKAIKLTANSMYGCLGFSSSRFHASAIAALITKTGRETLLRTKDIAENK 1044
Query: 1058 LNLEVIYGDTDSIMIYSGLDDIAKATSISKKVIQEVNKKYRCLEIDLDGLYKRMLLLKKK 1117
L V+YGDTDSIMI +G + + ++ + KK+ EVN Y+CLEI++DG++K +LLLKKK
Sbjct: 1045 LGFNVVYGDTDSIMINTGTNQLQQSLEMGKKLKVEVNCLYKCLEIEIDGVFKSLLLLKKK 1104
Query: 1118 KYAAVKVQFKDGTPYEVI-ERKGLDIVRRDWSLLAKDLGDFCLTQILSGGSCEDVVESIH 1176
KYAA++ + +VI E KGLD+VRRDW L+K +G++ L+QILSG EDVV +++
Sbjct: 1105 KYAALRYEGVGSNEVKVIQEMKGLDMVRRDWCPLSKSIGNYVLSQILSGKQREDVVFNLN 1164
Query: 1177 NSLMKVQEEMRNGQVALEKYVITKTLTKPPEAYPDAKNQPHVLVAQRLKQQGYTSGCSVG 1236
L + E+M++ ++ L++++ITK LT+ Y D K QPHV VAQRLK QG + V
Sbjct: 1165 EYLSDIGEKMKSNRITLDQFIITKQLTRAISEYSDIKGQPHVAVAQRLKNQGKSEADLVN 1224
Query: 1237 DTIPYVICCEQGGSSGSATGIALRARHPDELKQEQGTWLIDIDYYLSQQIHPVISRLCAS 1296
+ IPYVI + ++ S ++ +A HPDEL +G +DID+Y++ QI P I+RL
Sbjct: 1225 NFIPYVIGAQAFDTAKSNPQLSDKAYHPDELLSSKGKITLDIDWYITTQILPPITRLIEH 1284
Query: 1297 IQGTSPERLADCLGLDTSKFQHKSSEASDDPTSSLLFAGDDEES-EKPTSSGTDESDYNF 1355
I G + E +A CLG+D K+++ S + + D GDD S + P E
Sbjct: 1285 IDGINIEFVAQCLGVDPKKYKYHSEKKNTDE------IGDDGGSIQNPILQTETEKSLKH 1338
Query: 1356 WR----KLCCPKCFEN--------------------GAGRISAAMIANQVKRQAEKFVLM 1391
K+ CP C N +I + N+V ++ + +
Sbjct: 1339 RSIAELKVKCPSCTHNYDFPGIYQEGKDVSGLICTKCNAKIPEKYVMNRVNLFLKQLLAL 1398
Query: 1392 YYRGLLMCDDETCKHTTRSVSFRLVGDSERGTVCPNYPRCNGHLNRKYTEADLYKQLSYF 1451
YY+G C + +CK TR + + C N C G + +Y+E L Y
Sbjct: 1399 YYQGKYECQEPSCKSMTRQLLYH--------NKCVNL-TCKGKMVPEYSEHQTNDTLRYL 1449
Query: 1452 CHVFDTVCYIEKMEAKSRIPIEKEL 1476
+F+ ++ + + +E ++
Sbjct: 1450 QGLFNIKKHLHENSKNDSLKVETDI 1474
>gb|AAP45776.1| DNA polymerase catalytic subunit alpha [Stylonychia lemnae]
Length = 1514
Score = 649 bits (1673), Expect = 0.0
Identities = 407/1147 (35%), Positives = 613/1147 (52%), Gaps = 124/1147 (10%)
Query: 388 YQSCCVVVKNMQRCVYAIPSHPLHSTNEMIQLEKDVQESR---ISPADFRKKLQDAVSDT 444
Y SC + V MQR +YA+P + E++ Q R + D RKK
Sbjct: 394 YVSCSMKVNGMQREIYALPKMQKGKARGTLTREEENQLVRGVQLELEDIRKKRFQ----- 448
Query: 445 KNEIAKHLVDLGVSSFSMAPVKRKYAFERTDIPAGENYVVKINYLFKDTALPVDLKGKSF 504
G++ + PV RKYAFE I GE+ +KI Y LP ++G +F
Sbjct: 449 -----------GITKWRCKPVTRKYAFEMP-IQHGEHLFLKIKYDATFIPLPSTVQGNTF 496
Query: 505 CALLGARNSALELFLIKRKIKGPSWLQVSNFSTCSASQRVSWCKFEVIVDSPKDIRASSP 564
L G+ S LELF++KRKIKGP W+ + N + ++ +WC+ E+ +D+PK+ +
Sbjct: 497 ECLFGSNQSMLELFILKRKIKGPCWMTIKNPKKVTDFKK-TWCRQEIEIDNPKNAEVTLD 555
Query: 565 SSSKITLVNPPVVVTAINLKTTINEKQNINEIVSASVVSCNMVKIDTPMLASEWKRPGML 624
+K + PP+ KT + N NEI S + N V + P +++
Sbjct: 556 DLNKTDI--PPLTSLTFAFKTA-RSQNNTNEIAMISCLVHNNVNQEGPSQTDKFQT---- 608
Query: 625 THFTVIRKLDGNIFPMGFNTEVTDRNIKAGSNVLCVESSERALLNRLMLQLHKMDSDVLV 684
FT++RKLDG P F D+ ++ + ++ER +++ + ++ ++D D++V
Sbjct: 609 --FTLVRKLDGKPMPFDF-----DQKLRQKKENIQYFTNERQMIDLFVTRIFQIDPDLIV 661
Query: 685 GHNISGFDLDVLLHRSQACRVPSSMWSKLGRLNRSTMP--KLDRRGKTFGFGADPAIMSC 742
HN+ G D+LL R Q ++ + WS++GR + +P K D G +G G+
Sbjct: 662 AHNLCGGIFDLLLARIQILKI--NHWSRIGRFKKGNIPTKKFDTGGANYG-GSQWIPRQV 718
Query: 743 VAGRLLCDTYLCSRDLLKEVSYSLTHLAKTQLNQSRKEVAPHEVPKMFQTAKSLMELIEY 802
GRLL DT+L +++L++E +Y LTHL K QL + R++ +P+ + ++ + +LIE+
Sbjct: 719 TCGRLLVDTFLSAKELIRETNYDLTHLTKVQLKKDRQDFDDDLLPQFYLASERIFQLIEH 778
Query: 803 GETDAWLSMELMFYLSVLPLTRQLTNLSGNLWGKTLQGARAQRVEYLLLHEFHKKKYIVP 862
E D++ + LM +LS++PLT+QLTN++GNLW ++LQ ARA+R E LLLHEF KKK+I+P
Sbjct: 779 SEKDSYYTFMLMLHLSIIPLTKQLTNIAGNLWFRSLQNARAERNEMLLLHEFKKKKFILP 838
Query: 863 DKFSNYAKETKLTKRRVTHGVDDGNFDDADINDANYHNDASESDHKKNK-KAASYAGGLV 921
DK AK+ + + D ND K K K A YAGGLV
Sbjct: 839 DKKPPNAKDLRR----------------GFMGDEYEENDTKGGGKKGGKRKKAKYAGGLV 882
Query: 922 LEPKKGLYDKYILLLDFNSLYPSIIQEYNICFTTVERSSDDSFPR--------------- 966
+EPK G YD ILLLDFNSLYPSIIQEYN+CFTTV R ++
Sbjct: 883 IEPKAGFYDNIILLLDFNSLYPSIIQEYNLCFTTVNRRPTKNYDGSELKNQYKSADNAEG 942
Query: 967 -------LPSSKTT---GVLPELLKKLVKLRREKKTWMKTASG-LKRQQLDIEQQALKLT 1015
LP VLP +L+ LV+ R+ K MK +K QQL+I Q+A+KLT
Sbjct: 943 DEVEDVDLPDKNVNIKDAVLPNVLRDLVQKRKAVKEKMKNEKDQVKLQQLEIRQKAIKLT 1002
Query: 1016 ANSMYGCLGFSNSRFYAKPLAELITLQGREILQSTVDLVQNNLNLEVIYGDTDSIMIYSG 1075
ANSMYGCLGFS+SRF+A +A LIT GRE L T D+ +N L V+YGDTDSIMI +G
Sbjct: 1003 ANSMYGCLGFSSSRFHASAIAALITKTGRETLLRTKDIAENKLGFNVVYGDTDSIMINTG 1062
Query: 1076 LDDIAKATSISKKVIQEVNKKYRCLEIDLDGLYKRMLLLKKKKYAAVKVQFKDGTPYEVI 1135
+ + ++ + KK+ EVN Y+CLEI++DG++K +LLLKKKKYAA++ + +VI
Sbjct: 1063 TNQLQQSLEMGKKLKVEVNCLYKCLEIEIDGVFKSLLLLKKKKYAALRYEGVGSNEVKVI 1122
Query: 1136 -ERKGLDIVRRDWSLLAKDLGDFCLTQILSGGSCEDVVESIHNSLMKVQEEMRNGQVALE 1194
E KGLD+VRRDW L+K +G++ L+QILSG EDVV +++ L + E+M++ ++ L+
Sbjct: 1123 QEMKGLDMVRRDWCPLSKSIGNYVLSQILSGKQREDVVFNLNEYLSDIGEKMKSNRITLD 1182
Query: 1195 KYVITKTLTKPPEAYPDAKNQPHVLVAQRLKQQGYTSGCSVGDTIPYVICCEQGGSSGSA 1254
+++ITK LT+ Y D K QPHV VAQRLK QG + V + IPYVI + ++ S
Sbjct: 1183 QFIITKQLTRAISEYSDIKGQPHVAVAQRLKNQGKSEADLVNNFIPYVIGAQAFDTAKSN 1242
Query: 1255 TGIALRARHPDELKQEQGTWLIDIDYYLSQQIHPVISRLCASIQGTSPERLADCLGLDTS 1314
++ +A HPDEL +G +DID+Y++ QI P I+RL I G + E +A CLG+D
Sbjct: 1243 PQLSDKAYHPDELLSSKGKITLDIDWYITTQILPPITRLIEHIDGINIEFVAQCLGVDPK 1302
Query: 1315 KFQHKSSEASDDPTSSLLFAGDDEES-EKPTSSGTDESDYNFWR----KLCCPKCFEN-- 1367
K+++ S + + D GDD S + P E K+ CP C N
Sbjct: 1303 KYKYHSEKKNTDE------IGDDGGSIQNPILQTETEKSLKHRSIAELKVKCPSCTHNYD 1356
Query: 1368 ------------------GAGRISAAMIANQVKRQAEKFVLMYYRGLLMCDDETCKHTTR 1409
+I + N+V ++ + +YY+G C + +CK TR
Sbjct: 1357 FPGIYQEGKDVSGLICTKCNAKIPEKYVMNRVNLFLKQLLALYYQGKYECQEPSCKSMTR 1416
Query: 1410 SVSFRLVGDSERGTVCPNYPRCNGHLNRKYTEADLYKQLSYFCHVFDTVCYIEKMEAKSR 1469
+ + C N C G + +Y+E L Y +F+ ++ +
Sbjct: 1417 QLLYH--------NKCVNL-TCKGKMVPEYSEHQTNDTLRYLQGLFNIKKHLHENSKNDS 1467
Query: 1470 IPIEKEL 1476
+ +E ++
Sbjct: 1468 LKVETDI 1474
Database: nr
Posted date: Jul 5, 2005 12:34 AM
Number of letters in database: 863,360,394
Number of sequences in database: 2,540,612
Lambda K H
0.337 0.147 0.483
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 2,392,385,024
Number of Sequences: 2540612
Number of extensions: 98135246
Number of successful extensions: 399786
Number of sequences better than 10.0: 988
Number of HSP's better than 10.0 without gapping: 818
Number of HSP's successfully gapped in prelim test: 170
Number of HSP's that attempted gapping in prelim test: 394335
Number of HSP's gapped (non-prelim): 2121
length of query: 1510
length of database: 863,360,394
effective HSP length: 141
effective length of query: 1369
effective length of database: 505,134,102
effective search space: 691528585638
effective search space used: 691528585638
T: 11
A: 40
X1: 15 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 39 (21.7 bits)
S2: 82 (36.2 bits)
Medicago: description of AC144431.4