BLAST2 result
BLASTP 2.2.2 [Dec-14-2001]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= AC140916.11 - phase: 0
(363 letters)
Database: nr
2,540,612 sequences; 863,360,394 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
emb|CAC83625.1| 8-oxoguanine-DNA glycosylase [Arabidopsis thalia... 426 e-118
gb|AAD41425.1| Similar to gb|U96710 8-oxoguanine DNA-glycosylase... 426 e-118
ref|XP_466174.1| putative 8-oxoguanine DNA glycosylase isoform 1... 359 6e-98
ref|XP_541781.1| PREDICTED: similar to N-glycosylase/DNA lyase [... 202 1e-50
gb|AAM74236.1| 8-oxoguanine DNA glycosylase [Homo sapiens] gi|21... 198 2e-49
gb|AAH00657.1| 8-oxoguanine DNA glycosylase, isoform 1a [Homo sa... 198 2e-49
pdb|1HU0|A Chain A, Crystal Structure Of An Hogg1-Dna Borohydrid... 198 2e-49
pdb|1FN7|A Chain A, Coupling Of Damage Recognition And Catalysis... 198 2e-49
sp|O08760|OGG1_MOUSE N-glycosylase/DNA lyase [Includes: 8-oxogua... 197 3e-49
ref|NP_035087.2| 8-oxoguanine DNA-glycosylase 1 [Mus musculus] g... 197 3e-49
emb|CAA72117.1| 8-oxoguanine DNA glycosylase-like protein [Mus m... 197 3e-49
emb|CAA73883.1| 8-oxoguanine DNA glycosylase [Mus musculus] 197 4e-49
ref|NP_110497.1| 8-oxoguanine DNA-glycosylase 1 [Rattus norvegic... 196 7e-49
gb|AAB68616.1| 8-hydroxyguanine glycosylase [Mus musculus] 196 7e-49
pdb|1N39|A Chain A, Structural And Biochemical Exploration Of A ... 196 7e-49
pdb|1EBM|A Chain A, Crystal Structure Of The Human 8-Oxoguanine ... 196 7e-49
pdb|1N3C|A Chain A, Structural And Biochemical Exploration Of A ... 196 9e-49
pdb|1N3A|A Chain A, Structural And Biochemical Exploration Of A ... 196 1e-48
gb|AAB61289.1| 8-oxoguanine DNA glycosylase 1; mOgg1 [Mus musculus] 195 2e-48
pdb|1YQK|A Chain A, Human 8-Oxoguanine Glycosylase Crosslinked W... 194 3e-48
>emb|CAC83625.1| 8-oxoguanine-DNA glycosylase [Arabidopsis thaliana]
gi|11967657|emb|CAC19363.1| 8-oxoguanine DNA glycosylase
[Arabidopsis thaliana] gi|15219068|ref|NP_173590.1|
8-oxoguanine-DNA glycosylase (OGG1) [Arabidopsis
thaliana] gi|51971190|dbj|BAD44287.1| 8-oxoguanine DNA
glycosylase-like protein [Arabidopsis thaliana]
Length = 365
Score = 426 bits (1096), Expect = e-118
Identities = 212/330 (64%), Positives = 255/330 (77%), Gaps = 7/330 (2%)
Query: 13 PPPLPPSTPPTPHTQTRHSTNLSKSRAWIPLNITRQELSLPLTFPTGQTFRWKNTAPSQY 72
PP PP TP Q H T K W PL +T EL+LPLTFPTGQTFRWK T QY
Sbjct: 18 PPLSPPVTPILK--QKLHRTGTPK---WFPLKLTHTELTLPLTFPTGQTFRWKKTGAIQY 72
Query: 73 TGVVGSHLISLKHLHNGD-VCYTLHSQSPSNDDCKTALLDFLNADVSLADTWKVFSDSDE 131
+G +G HL+SL+ D V Y +H S S + ALLDFLNA++SLA+ W FS D
Sbjct: 73 SGTIGPHLVSLRQRPGDDAVSYCVHC-STSPKSAELALLDFLNAEISLAELWSDFSKKDP 131
Query: 132 RFAELAQHLSGARVLRQDPFECLIQFMCSSNNHISRITKMVDYVSSLGTYLGCVEGFDFH 191
RF ELA+HL GARVLRQDP ECLIQF+CSSNN+I+RITKMVD+VSSLG +LG ++GF+FH
Sbjct: 132 RFGELARHLRGARVLRQDPLECLIQFLCSSNNNIARITKMVDFVSSLGLHLGDIDGFEFH 191
Query: 192 AFPTLNQLSLVSEQQLRDAGFGYRAKYITGTVNVLQSKPEGGEEWLYSLRKLELEDVISE 251
FP+L++LS VSE++ R AGFGYRAKYITGTVN LQ+KP GG EWL SLRK+EL++ ++
Sbjct: 192 QFPSLDRLSRVSEEEFRKAGFGYRAKYITGTVNALQAKPGGGNEWLLSLRKVELQEAVAA 251
Query: 252 LIKLPGVGPKVAACIALYSLDQHHAIPVDVHIWRIAQKYILPELAGSKLTQKLHSRVAEA 311
L LPGVGPKVAACIAL+SLDQH AIPVD H+W+IA Y+LP+LAG+KLT KLH RVAEA
Sbjct: 252 LCTLPGVGPKVAACIALFSLDQHSAIPVDTHVWQIATNYLLPDLAGAKLTPKLHGRVAEA 311
Query: 312 FVTKFGKYAGWAQAVLFIAELPSQKAILPS 341
FV+K+G+YAGWAQ +LFIAELP+QK +L S
Sbjct: 312 FVSKYGEYAGWAQTLLFIAELPAQKTLLQS 341
>gb|AAD41425.1| Similar to gb|U96710 8-oxoguanine DNA-glycosylase from Homo
sapiens. [Arabidopsis thaliana] gi|25349383|pir||E86350
F8K7.14 protein - Arabidopsis thaliana
Length = 391
Score = 426 bits (1096), Expect = e-118
Identities = 212/330 (64%), Positives = 255/330 (77%), Gaps = 7/330 (2%)
Query: 13 PPPLPPSTPPTPHTQTRHSTNLSKSRAWIPLNITRQELSLPLTFPTGQTFRWKNTAPSQY 72
PP PP TP Q H T K W PL +T EL+LPLTFPTGQTFRWK T QY
Sbjct: 18 PPLSPPVTPILK--QKLHRTGTPK---WFPLKLTHTELTLPLTFPTGQTFRWKKTGAIQY 72
Query: 73 TGVVGSHLISLKHLHNGD-VCYTLHSQSPSNDDCKTALLDFLNADVSLADTWKVFSDSDE 131
+G +G HL+SL+ D V Y +H S S + ALLDFLNA++SLA+ W FS D
Sbjct: 73 SGTIGPHLVSLRQRPGDDAVSYCVHC-STSPKSAELALLDFLNAEISLAELWSDFSKKDP 131
Query: 132 RFAELAQHLSGARVLRQDPFECLIQFMCSSNNHISRITKMVDYVSSLGTYLGCVEGFDFH 191
RF ELA+HL GARVLRQDP ECLIQF+CSSNN+I+RITKMVD+VSSLG +LG ++GF+FH
Sbjct: 132 RFGELARHLRGARVLRQDPLECLIQFLCSSNNNIARITKMVDFVSSLGLHLGDIDGFEFH 191
Query: 192 AFPTLNQLSLVSEQQLRDAGFGYRAKYITGTVNVLQSKPEGGEEWLYSLRKLELEDVISE 251
FP+L++LS VSE++ R AGFGYRAKYITGTVN LQ+KP GG EWL SLRK+EL++ ++
Sbjct: 192 QFPSLDRLSRVSEEEFRKAGFGYRAKYITGTVNALQAKPGGGNEWLLSLRKVELQEAVAA 251
Query: 252 LIKLPGVGPKVAACIALYSLDQHHAIPVDVHIWRIAQKYILPELAGSKLTQKLHSRVAEA 311
L LPGVGPKVAACIAL+SLDQH AIPVD H+W+IA Y+LP+LAG+KLT KLH RVAEA
Sbjct: 252 LCTLPGVGPKVAACIALFSLDQHSAIPVDTHVWQIATNYLLPDLAGAKLTPKLHGRVAEA 311
Query: 312 FVTKFGKYAGWAQAVLFIAELPSQKAILPS 341
FV+K+G+YAGWAQ +LFIAELP+QK +L S
Sbjct: 312 FVSKYGEYAGWAQTLLFIAELPAQKTLLQS 341
>ref|XP_466174.1| putative 8-oxoguanine DNA glycosylase isoform 1a; 8-hydroxyguanine
DNA glycosylase [Oryza sativa (japonica cultivar-group)]
gi|46389889|dbj|BAD15490.1| putative 8-oxoguanine DNA
glycosylase isoform 1a; 8-hydroxyguanine DNA glycosylase
[Oryza sativa (japonica cultivar-group)]
Length = 399
Score = 359 bits (922), Expect = 6e-98
Identities = 194/371 (52%), Positives = 248/371 (66%), Gaps = 34/371 (9%)
Query: 3 KRKRSPIKSLPPPL------PPSTPP--TPHTQT--------RHSTNLSKSRA------- 39
+R R P+ PP L PP TPP TP ++ R L + A
Sbjct: 7 RRVRPPLPPSPPLLSSTTATPPPTPPVGTPKSEAADRRPPPARRRLPLVSAAAVEEEDGE 66
Query: 40 WIPLNITRQELSLPLTFPTGQTFRWKNTA--PSQYTGVVGSHLISLKHLHNGD--VCYTL 95
W PL ++ +LSLPLT PTGQTF W+ T+ P ++TG VG HL+SL HL + D + + L
Sbjct: 67 WHPLPLSAADLSLPLTLPTGQTFLWRRTSLSPLRFTGAVGPHLVSLSHLPSSDGRLAFLL 126
Query: 96 HSQSPSNDD-----CKTALLDFLNADVSLADTWKVFSDSDERFAELAQHLSG--ARVLRQ 148
H+ S+ + AL D+LNA V LAD W+ F+ +D RFAE++ L G ARVLRQ
Sbjct: 127 HNNGGSSSSSVPAAARAALSDYLNAAVPLADLWRRFAAADARFAEVSARLGGGGARVLRQ 186
Query: 149 DPFECLIQFMCSSNNHISRITKMVDYVSSLGTYLGCVEGFDFHAFPTLNQLSLVSEQQLR 208
DP EC+ QF+CSSNN+I+RI KMV ++ G LG V G+ FH FPT+ +L+ VSEQ+LR
Sbjct: 187 DPVECVFQFLCSSNNNIARIEKMVWALAGYGERLGEVGGYQFHQFPTIERLARVSEQELR 246
Query: 209 DAGFGYRAKYITGTVNVLQSKPEGGEEWLYSLRKLELEDVISELIKLPGVGPKVAACIAL 268
DAGFGYRAKYI GT +LQ+KP GGE+WL SLR EL +VI L LPGVGPKVAAC+AL
Sbjct: 247 DAGFGYRAKYIVGTAKILQAKPGGGEKWLASLRTRELPEVIEALCTLPGVGPKVAACVAL 306
Query: 269 YSLDQHHAIPVDVHIWRIAQKYILPELAGSKLTQKLHSRVAEAFVTKFGKYAGWAQAVLF 328
+SLDQ+HAIPVD H+W++A +Y++PELAG LT KL VA+AFV KFG YAGWAQ VLF
Sbjct: 307 FSLDQNHAIPVDTHVWKVATQYLMPELAGKSLTPKLSVAVADAFVAKFGNYAGWAQNVLF 366
Query: 329 IAELPSQKAIL 339
I +L +QK ++
Sbjct: 367 IGQLSAQKLMV 377
>ref|XP_541781.1| PREDICTED: similar to N-glycosylase/DNA lyase [Canis familiaris]
Length = 554
Score = 202 bits (515), Expect = 1e-50
Identities = 119/313 (38%), Positives = 176/313 (56%), Gaps = 12/313 (3%)
Query: 30 HSTNLSKSRAWIPLNITRQELSLPLTFPTGQTFRWKNTAPSQYTGVVGSHLISLKHLHNG 89
H T S W + R EL L L +GQ+FRW+ P+ +TGV+ + + +L
Sbjct: 223 HRTLSSFPALWASIPCPRSELRLDLVLASGQSFRWREQDPAHWTGVLANRVWTLTQTEEK 282
Query: 90 DVCYTLHSQS-----PSNDDCKTALLDFLNADVSLADTWKVFSDSDERFAELAQHLSGAR 144
C + P+ ++ KT + + DVSLA + +S +D F E++Q G R
Sbjct: 283 LYCTVYRDDNGWVGRPTPEELKT-VHQYFQLDVSLAQLYHHWSSADPHFQEVSQKFQGVR 341
Query: 145 VLRQDPFECLIQFMCSSNNHISRITKMVDYV-SSLGTYLGCVEGFDFHAFPTLNQLSLVS 203
+L+QDP ECL F+CSSNN+I+RIT MV+ + + G L ++ +H FP+L L+
Sbjct: 342 LLQQDPIECLFSFICSSNNNIARITGMVERLCQAFGPRLIQLDDVTYHGFPSLQALAGPE 401
Query: 204 -EQQLRDAGFGYRAKYITGTVNVLQSKPEGGEEWLYSLRKLELEDVISELIKLPGVGPKV 262
E QLR G GYRA+Y++ + + + +GG WL LRK E+ L LPGVG KV
Sbjct: 402 VEAQLRKLGLGYRARYVSASARAILEE-QGGLPWLQQLRKAPYEEAHKALCTLPGVGTKV 460
Query: 263 AACIALYSLDQHHAIPVDVHIWRIAQKYIL--PELAGSK-LTQKLHSRVAEAFVTKFGKY 319
A CI L +LD+ A+PVDVH+W+IAQ+ P + +K + + + + F + +G Y
Sbjct: 461 ADCICLMALDKPQAVPVDVHVWQIAQRDYSWHPSTSQAKGPSPQTNKELGNFFRSLWGPY 520
Query: 320 AGWAQAVLFIAEL 332
AGWAQAVLF A+L
Sbjct: 521 AGWAQAVLFSADL 533
>gb|AAM74236.1| 8-oxoguanine DNA glycosylase [Homo sapiens]
gi|2197083|gb|AAB61340.1| 8-oxoguanine DNA glycosylase 1
[Homo sapiens] gi|1903206|emb|CAA72536.1| 8-oxoguanine
DNA glycosylase homolog 1 [Homo sapiens]
gi|5305498|gb|AAD41680.1| 8-hydroxyguanine-specific DNA
glycosylase type 1a [Homo sapiens]
gi|12643548|sp|O15527|OGG1_HUMAN N-glycosylase/DNA lyase
[Includes: 8-oxoguanine DNA glycosylase ; DNA-(apurinic
or apyrimidinic site) lyase (AP lyase)]
gi|4505495|ref|NP_002533.1| 8-oxoguanine DNA glycosylase
isoform 1a [Homo sapiens] gi|2351704|gb|AAB68614.1|
8-hydroxyguanine glycosylase/lyase [Homo sapiens]
gi|1890182|emb|CAA72414.1| DNA glycosylase/AP lyase
[Homo sapiens] gi|18158657|pdb|1KO9|A Chain A, Native
Structure Of The Human 8-Oxoguanine Dna Glycosylase
Hogg1 gi|1906757|dbj|BAA19103.1| hOGG1 [Homo sapiens]
Length = 345
Score = 198 bits (503), Expect = 2e-49
Identities = 117/313 (37%), Positives = 172/313 (54%), Gaps = 12/313 (3%)
Query: 30 HSTNLSKSRAWIPLNITRQELSLPLTFPTGQTFRWKNTAPSQYTGVVGSHLISLKHLHNG 89
H T S W + R EL L L P+GQ+FRW+ +P+ ++GV+ + +L
Sbjct: 13 HRTLASTPALWASIPCPRSELRLDLVLPSGQSFRWREQSPAHWSGVLADQVWTLTQTEEQ 72
Query: 90 DVCYTLHSQS-----PSNDDCKTALLDFLNADVSLADTWKVFSDSDERFAELAQHLSGAR 144
C P+ D+ + A+ + DV+LA + + D F E+AQ G R
Sbjct: 73 LHCTVYRGDKSQASRPTPDELE-AVRKYFQLDVTLAQLYHHWGSVDSHFQEVAQKFQGVR 131
Query: 145 VLRQDPFECLIQFMCSSNNHISRITKMVDYV-SSLGTYLGCVEGFDFHAFPTLNQLSLVS 203
+LRQDP ECL F+CSSNN+I+RIT MV+ + + G L ++ +H FP+L L+
Sbjct: 132 LLRQDPIECLFSFICSSNNNIARITGMVERLCQAFGPRLIQLDDVTYHGFPSLQALAGPE 191
Query: 204 -EQQLRDAGFGYRAKYITGTVNVLQSKPEGGEEWLYSLRKLELEDVISELIKLPGVGPKV 262
E LR G GYRA+Y++ + + + +GG WL LR+ E+ L LPGVG KV
Sbjct: 192 VEAHLRKLGLGYRARYVSASARAILEE-QGGLAWLQQLRESSYEEAHKALCILPGVGTKV 250
Query: 263 AACIALYSLDQHHAIPVDVHIWRIAQKYIL--PELAGSK-LTQKLHSRVAEAFVTKFGKY 319
A CI L +LD+ A+PVDVH+W IAQ+ P + +K + + + + F + +G Y
Sbjct: 251 ADCICLMALDKPQAVPVDVHMWHIAQRDYSWHPTTSQAKGPSPQTNKELGNFFRSLWGPY 310
Query: 320 AGWAQAVLFIAEL 332
AGWAQAVLF A+L
Sbjct: 311 AGWAQAVLFSADL 323
>gb|AAH00657.1| 8-oxoguanine DNA glycosylase, isoform 1a [Homo sapiens]
Length = 345
Score = 198 bits (503), Expect = 2e-49
Identities = 117/313 (37%), Positives = 172/313 (54%), Gaps = 12/313 (3%)
Query: 30 HSTNLSKSRAWIPLNITRQELSLPLTFPTGQTFRWKNTAPSQYTGVVGSHLISLKHLHNG 89
H T S W + R EL L L P+GQ+FRW+ +P+ ++GV+ + +L
Sbjct: 13 HRTLASTPALWASIPCPRSELRLDLVLPSGQSFRWREQSPAHWSGVLADQVWTLTQTEEQ 72
Query: 90 DVCYTLHSQS-----PSNDDCKTALLDFLNADVSLADTWKVFSDSDERFAELAQHLSGAR 144
C P+ D+ + A+ + DV+LA + + D F E+AQ G R
Sbjct: 73 LHCTVYRGDKSQASRPTPDELE-AVRKYFQLDVTLAQLYHHWGSVDSHFQEVAQKFQGVR 131
Query: 145 VLRQDPFECLIQFMCSSNNHISRITKMVDYV-SSLGTYLGCVEGFDFHAFPTLNQLSLVS 203
+LRQDP ECL F+CSSNN+I+RIT MV+ + + G L ++ +H FP+L L+
Sbjct: 132 LLRQDPIECLFSFICSSNNNIARITGMVERLCQAFGPRLIQLDDVTYHGFPSLQALAGPE 191
Query: 204 -EQQLRDAGFGYRAKYITGTVNVLQSKPEGGEEWLYSLRKLELEDVISELIKLPGVGPKV 262
E LR G GYRA+Y++ + + + +GG WL LR+ E+ L LPGVG KV
Sbjct: 192 VEAHLRKLGLGYRARYVSASARAILEE-QGGLAWLQQLRESSYEEAHKALCILPGVGTKV 250
Query: 263 AACIALYSLDQHHAIPVDVHIWRIAQKYIL--PELAGSK-LTQKLHSRVAEAFVTKFGKY 319
A CI L +LD+ A+PVDVH+W IAQ+ P + +K + + + + F + +G Y
Sbjct: 251 ADCICLMALDKPQAVPVDVHMWHIAQRDYSWHPTTSQAKGPSPQTNKELGNFFRSLWGPY 310
Query: 320 AGWAQAVLFIAEL 332
AGWAQAVLF A+L
Sbjct: 311 AGWAQAVLFSADL 323
>pdb|1HU0|A Chain A, Crystal Structure Of An Hogg1-Dna Borohydride Trapped
Intermediate Complex gi|28948504|pdb|1LWY|A Chain A,
Hogg1 Borohydride-Trapped Intermediate Without
8-Oxoguanine gi|28948501|pdb|1LWW|A Chain A,
Borohydride-Trapped Hogg1 Intermediate Structure Co-
Crystallized With 8-Bromoguanine gi|28948498|pdb|1LWV|A
Chain A, Borohydride-Trapped Hogg1 Intermediate
Structure Co- Crystallized With 8-Aminoguanine
Length = 324
Score = 198 bits (503), Expect = 2e-49
Identities = 117/313 (37%), Positives = 172/313 (54%), Gaps = 12/313 (3%)
Query: 30 HSTNLSKSRAWIPLNITRQELSLPLTFPTGQTFRWKNTAPSQYTGVVGSHLISLKHLHNG 89
H T S W + R EL L L P+GQ+FRW+ +P+ ++GV+ + +L
Sbjct: 10 HRTLASTPALWASIPCPRSELRLDLVLPSGQSFRWREQSPAHWSGVLADQVWTLTQTEEQ 69
Query: 90 DVCYTLHSQS-----PSNDDCKTALLDFLNADVSLADTWKVFSDSDERFAELAQHLSGAR 144
C P+ D+ + A+ + DV+LA + + D F E+AQ G R
Sbjct: 70 LHCTVYRGDKSQASRPTPDELE-AVRKYFQLDVTLAQLYHHWGSVDSHFQEVAQKFQGVR 128
Query: 145 VLRQDPFECLIQFMCSSNNHISRITKMVDYV-SSLGTYLGCVEGFDFHAFPTLNQLSLVS 203
+LRQDP ECL F+CSSNN+I+RIT MV+ + + G L ++ +H FP+L L+
Sbjct: 129 LLRQDPIECLFSFICSSNNNIARITGMVERLCQAFGPRLIQLDDVTYHGFPSLQALAGPE 188
Query: 204 -EQQLRDAGFGYRAKYITGTVNVLQSKPEGGEEWLYSLRKLELEDVISELIKLPGVGPKV 262
E LR G GYRA+Y++ + + + +GG WL LR+ E+ L LPGVG KV
Sbjct: 189 VEAHLRKLGLGYRARYVSASARAILEE-QGGLAWLQQLRESSYEEAHKALCILPGVGTKV 247
Query: 263 AACIALYSLDQHHAIPVDVHIWRIAQKYIL--PELAGSK-LTQKLHSRVAEAFVTKFGKY 319
A CI L +LD+ A+PVDVH+W IAQ+ P + +K + + + + F + +G Y
Sbjct: 248 ADCICLMALDKPQAVPVDVHMWHIAQRDYSWHPTTSQAKGPSPQTNKELGNFFRSLWGPY 307
Query: 320 AGWAQAVLFIAEL 332
AGWAQAVLF A+L
Sbjct: 308 AGWAQAVLFSADL 320
>pdb|1FN7|A Chain A, Coupling Of Damage Recognition And Catalysis By A Human
Base-Excision Dna Repair Protein
Length = 317
Score = 198 bits (503), Expect = 2e-49
Identities = 117/313 (37%), Positives = 172/313 (54%), Gaps = 12/313 (3%)
Query: 30 HSTNLSKSRAWIPLNITRQELSLPLTFPTGQTFRWKNTAPSQYTGVVGSHLISLKHLHNG 89
H T S W + R EL L L P+GQ+FRW+ +P+ ++GV+ + +L
Sbjct: 5 HRTLASTPALWASIPCPRSELRLDLVLPSGQSFRWREQSPAHWSGVLADQVWTLTQTEEQ 64
Query: 90 DVCYTLHSQS-----PSNDDCKTALLDFLNADVSLADTWKVFSDSDERFAELAQHLSGAR 144
C P+ D+ + A+ + DV+LA + + D F E+AQ G R
Sbjct: 65 LHCTVYRGDKSQASRPTPDELE-AVRKYFQLDVTLAQLYHHWGSVDSHFQEVAQKFQGVR 123
Query: 145 VLRQDPFECLIQFMCSSNNHISRITKMVDYV-SSLGTYLGCVEGFDFHAFPTLNQLSLVS 203
+LRQDP ECL F+CSSNN+I+RIT MV+ + + G L ++ +H FP+L L+
Sbjct: 124 LLRQDPIECLFSFICSSNNNIARITGMVERLCQAFGPRLIQLDDVTYHGFPSLQALAGPE 183
Query: 204 -EQQLRDAGFGYRAKYITGTVNVLQSKPEGGEEWLYSLRKLELEDVISELIKLPGVGPKV 262
E LR G GYRA+Y++ + + + +GG WL LR+ E+ L LPGVG KV
Sbjct: 184 VEAHLRKLGLGYRARYVSASARAILEE-QGGLAWLQQLRESSYEEAHKALCILPGVGTKV 242
Query: 263 AACIALYSLDQHHAIPVDVHIWRIAQKYIL--PELAGSK-LTQKLHSRVAEAFVTKFGKY 319
A CI L +LD+ A+PVDVH+W IAQ+ P + +K + + + + F + +G Y
Sbjct: 243 ADCICLMALDKPQAVPVDVHMWHIAQRDYSWHPTTSQAKGPSPQTNKELGNFFRSLWGPY 302
Query: 320 AGWAQAVLFIAEL 332
AGWAQAVLF A+L
Sbjct: 303 AGWAQAVLFSADL 315
>sp|O08760|OGG1_MOUSE N-glycosylase/DNA lyase [Includes: 8-oxoguanine DNA glycosylase ;
DNA-(apurinic or apyrimidinic site) lyase (AP lyase)]
gi|2738598|gb|AAB94512.1| 8-oxoguanine DNA glycosylase
[Mus musculus] gi|2257848|gb|AAB63151.1| mOGG1;
8-oxoguanine DNA glycosylase homolog [Mus musculus]
Length = 345
Score = 197 bits (502), Expect = 3e-49
Identities = 118/314 (37%), Positives = 171/314 (53%), Gaps = 12/314 (3%)
Query: 29 RHSTNLSKSRAWIPLNITRQELSLPLTFPTGQTFRWKNTAPSQYTGVVGSHLISLKHLHN 88
RH T S W + R EL L L +GQ+FRWK +P+ ++GV+ + +L +
Sbjct: 12 RHRTLSSSPALWASIPCPRSELRLDLVLASGQSFRWKEQSPAHWSGVLADQVWTLTQTED 71
Query: 89 GDVCYTLHSQS-----PSNDDCKTALLDFLNADVSLADTWKVFSDSDERFAELAQHLSGA 143
C P+ ++ +T L + DVSLA + ++ D F +AQ G
Sbjct: 72 QLYCTVYRGDDSQVSRPTLEELET-LHKYFQLDVSLAQLYSHWASVDSHFQRVAQKFQGV 130
Query: 144 RVLRQDPFECLIQFMCSSNNHISRITKMVDYV-SSLGTYLGCVEGFDFHAFPTLNQLS-L 201
R+LRQDP ECL F+CSSNN+I+RIT MV+ + + G L ++ +H FP L+ L+
Sbjct: 131 RLLRQDPTECLFSFICSSNNNIARITGMVERLCQAFGPRLIQLDDVTYHGFPNLHALAGP 190
Query: 202 VSEQQLRDAGFGYRAKYITGTVNVLQSKPEGGEEWLYSLRKLELEDVISELIKLPGVGPK 261
+E LR G GYRA+Y+ + + + +GG WL LR E+ L LPGVG K
Sbjct: 191 EAETHLRKLGLGYRARYVRASAKAILEE-QGGPAWLQQLRVAPYEEAHKALCTLPGVGAK 249
Query: 262 VAACIALYSLDQHHAIPVDVHIWRIAQKYI--LPELAGSKLTQKL-HSRVAEAFVTKFGK 318
VA CI L +LD+ A+PVDVH+W+IA + P+ + +K L + + F +G
Sbjct: 250 VADCICLMALDKPQAVPVDVHVWQIAHRDYGWHPKTSQAKGPSPLANKELGNFFRNLWGP 309
Query: 319 YAGWAQAVLFIAEL 332
YAGWAQAVLF A+L
Sbjct: 310 YAGWAQAVLFSADL 323
>ref|NP_035087.2| 8-oxoguanine DNA-glycosylase 1 [Mus musculus]
gi|2078296|gb|AAB81133.1| 8-oxoguanine DNA-glycosylase
[Mus musculus]
Length = 345
Score = 197 bits (502), Expect = 3e-49
Identities = 118/314 (37%), Positives = 171/314 (53%), Gaps = 12/314 (3%)
Query: 29 RHSTNLSKSRAWIPLNITRQELSLPLTFPTGQTFRWKNTAPSQYTGVVGSHLISLKHLHN 88
RH T S W + R EL L L +GQ+FRWK +P+ ++GV+ + +L +
Sbjct: 12 RHRTLSSSPALWASIPCPRSELRLDLVLASGQSFRWKEQSPAHWSGVLADQVWTLTQTED 71
Query: 89 GDVCYTLHSQS-----PSNDDCKTALLDFLNADVSLADTWKVFSDSDERFAELAQHLSGA 143
C P+ ++ +T L + DVSLA + ++ D F +AQ G
Sbjct: 72 QLYCTVYRGDDSQVSRPTLEELET-LHKYFQLDVSLAQLYSHWASVDSHFQRVAQKFQGV 130
Query: 144 RVLRQDPFECLIQFMCSSNNHISRITKMVDYV-SSLGTYLGCVEGFDFHAFPTLNQLS-L 201
R+LRQDP ECL F+CSSNN+I+RIT MV+ + + G L ++ +H FP L+ L+
Sbjct: 131 RLLRQDPTECLFSFICSSNNNIARITGMVERLCQAFGPRLIQLDDVTYHGFPNLHALAGP 190
Query: 202 VSEQQLRDAGFGYRAKYITGTVNVLQSKPEGGEEWLYSLRKLELEDVISELIKLPGVGPK 261
+E LR G GYRA+Y+ + + + +GG WL LR E+ L LPGVG K
Sbjct: 191 EAETHLRKLGLGYRARYVRASAKAILEE-QGGPAWLQQLRVAPYEEAHKALCTLPGVGAK 249
Query: 262 VAACIALYSLDQHHAIPVDVHIWRIAQKYI--LPELAGSKLTQKL-HSRVAEAFVTKFGK 318
VA CI L +LD+ A+PVDVH+W+IA + P+ + +K L + + F +G
Sbjct: 250 VADCICLMALDKPQAVPVDVHVWQIAHRDYGWHPKTSQAKGPSPLANKELGNFFRNLWGP 309
Query: 319 YAGWAQAVLFIAEL 332
YAGWAQAVLF A+L
Sbjct: 310 YAGWAQAVLFSADL 323
>emb|CAA72117.1| 8-oxoguanine DNA glycosylase-like protein [Mus musculus]
gi|6688667|emb|CAB65240.1| 8-oxoguanine DNA glycosylase
1 [Mus musculus]
Length = 345
Score = 197 bits (502), Expect = 3e-49
Identities = 118/314 (37%), Positives = 171/314 (53%), Gaps = 12/314 (3%)
Query: 29 RHSTNLSKSRAWIPLNITRQELSLPLTFPTGQTFRWKNTAPSQYTGVVGSHLISLKHLHN 88
RH T S W + R EL L L +GQ+FRWK +P+ ++GV+ + +L +
Sbjct: 12 RHRTLSSSPALWASIPCPRSELRLDLVLASGQSFRWKEQSPAHWSGVLADQVWTLTQTED 71
Query: 89 GDVCYTLHSQS-----PSNDDCKTALLDFLNADVSLADTWKVFSDSDERFAELAQHLSGA 143
C P+ ++ +T L + DVSLA + ++ D F +AQ G
Sbjct: 72 QLYCTVYRGDDSQVSRPTLEELET-LHKYFQLDVSLAQLYSHWASVDSHFQRVAQKFQGV 130
Query: 144 RVLRQDPFECLIQFMCSSNNHISRITKMVDYV-SSLGTYLGCVEGFDFHAFPTLNQLS-L 201
R+LRQDP ECL F+CSSNN+I+RIT MV+ + + G L ++ +H FP L+ L+
Sbjct: 131 RLLRQDPTECLFSFICSSNNNIARITGMVERLCQAFGPRLIQLDDVTYHGFPNLHALAGP 190
Query: 202 VSEQQLRDAGFGYRAKYITGTVNVLQSKPEGGEEWLYSLRKLELEDVISELIKLPGVGPK 261
+E LR G GYRA+Y+ + + + +GG WL LR E+ L LPGVG K
Sbjct: 191 EAETHLRKLGLGYRARYVRASAKAILEE-QGGPAWLQQLRVAPYEEAHKALCTLPGVGAK 249
Query: 262 VAACIALYSLDQHHAIPVDVHIWRIAQKYI--LPELAGSKLTQKL-HSRVAEAFVTKFGK 318
VA CI L +LD+ A+PVDVH+W+IA + P+ + +K L + + F +G
Sbjct: 250 VADCICLMALDKPQAVPVDVHVWQIAHRDYGWHPKTSQAKGPSPLANKELGNFFRNLWGP 309
Query: 319 YAGWAQAVLFIAEL 332
YAGWAQAVLF A+L
Sbjct: 310 YAGWAQAVLFSADL 323
>emb|CAA73883.1| 8-oxoguanine DNA glycosylase [Mus musculus]
Length = 345
Score = 197 bits (501), Expect = 4e-49
Identities = 118/314 (37%), Positives = 172/314 (54%), Gaps = 12/314 (3%)
Query: 29 RHSTNLSKSRAWIPLNITRQELSLPLTFPTGQTFRWKNTAPSQYTGVVGSHLISLKHLHN 88
RH T S W + R EL L L +GQ+FRWK +P+ ++GV+ + +L +
Sbjct: 12 RHRTLSSSPALWASIPCPRSELRLDLVLASGQSFRWKEQSPAHWSGVLADQVWTLTQTED 71
Query: 89 GDVCYTLHSQS-----PSNDDCKTALLDFLNADVSLADTWKVFSDSDERFAELAQHLSGA 143
C P+ ++ +T L + DVSLA + ++ D F +AQ G
Sbjct: 72 QLYCTVYRGDDSQVSRPTLEELET-LHKYFQLDVSLAQLYSHWASVDSHFQRVAQKFQGV 130
Query: 144 RVLRQDPFECLIQFMCSSNNHISRITKMVDYV-SSLGTYLGCVEGFDFHAFPTLNQLS-L 201
R+LRQDP ECL F+CSSNN+I+RIT MV+ + + G L ++ +H FP L+ L+
Sbjct: 131 RLLRQDPTECLFSFICSSNNNIARITGMVERLCQAFGPRLIQLDDVTYHGFPNLHALAGP 190
Query: 202 VSEQQLRDAGFGYRAKYITGTVNVLQSKPEGGEEWLYSLRKLELEDVISELIKLPGVGPK 261
+E LR G GYRA+Y+ + + + +GG WL LR E+ L LPGVG K
Sbjct: 191 EAETHLRKLGLGYRARYVRASAKAILEE-QGGPAWLQQLRVAPYEEAHKALCTLPGVGAK 249
Query: 262 VAACIALYSLDQHHAIPVDVHIWRIAQKYI--LPELAGSKLTQKLHSRVAEAFVTK-FGK 318
VA CI L +LD+ A+PVDVH+W+IA + P+ + +K L ++ + F +G
Sbjct: 250 VADCICLMALDKPQAVPVDVHVWQIAHRDYGWHPKTSQAKGPSPLANKESGNFFRNLWGP 309
Query: 319 YAGWAQAVLFIAEL 332
YAGWAQAVLF A+L
Sbjct: 310 YAGWAQAVLFSADL 323
>ref|NP_110497.1| 8-oxoguanine DNA-glycosylase 1 [Rattus norvegicus]
gi|10720147|sp|O70249|OGG1_RAT N-glycosylase/DNA lyase
[Includes: 8-oxoguanine DNA glycosylase ; DNA-(apurinic
or apyrimidinic site) lyase (AP lyase)]
gi|3004865|gb|AAC77525.1| 8-oxoguanine-DNA-glycosylase
[Rattus norvegicus]
Length = 345
Score = 196 bits (499), Expect = 7e-49
Identities = 116/317 (36%), Positives = 170/317 (53%), Gaps = 12/317 (3%)
Query: 29 RHSTNLSKSRAWIPLNITRQELSLPLTFPTGQTFRWKNTAPSQYTGVVGSHLISLKHLHN 88
RH T S W + R EL L L +GQ+FRW+ +P+ ++GV+ + +L +
Sbjct: 12 RHRTLTSSPALWASIPCPRSELRLDLVLASGQSFRWREQSPAHWSGVLADQVWTLTQTED 71
Query: 89 GDVCYTLHSQS-----PSNDDCKTALLDFLNADVSLADTWKVFSDSDERFAELAQHLSGA 143
C P+ ++ +T L + DVSL + ++ D F +AQ G
Sbjct: 72 QLYCTVYRGDKGQVGRPTLEELET-LHKYFQLDVSLTQLYSHWASVDSHFQSVAQKFQGV 130
Query: 144 RVLRQDPFECLIQFMCSSNNHISRITKMVDYV-SSLGTYLGCVEGFDFHAFPTLNQLSLV 202
R+LRQDP ECL F+CSSNN+I+RIT MV+ + + G L ++ +H FP L+ L+
Sbjct: 131 RLLRQDPTECLFSFICSSNNNIARITGMVERLCQAFGPRLVQLDDVTYHGFPNLHALAGP 190
Query: 203 S-EQQLRDAGFGYRAKYITGTVNVLQSKPEGGEEWLYSLRKLELEDVISELIKLPGVGPK 261
E LR G GYRA+Y+ + + + +GG WL LR E+ L LPGVG K
Sbjct: 191 EVETHLRKLGLGYRARYVCASAKAILEE-QGGPAWLQQLRVASYEEAHKALCTLPGVGTK 249
Query: 262 VAACIALYSLDQHHAIPVDVHIWRIAQKYI--LPELAGSKLTQKL-HSRVAEAFVTKFGK 318
VA CI L +LD+ A+PVD+H+W+IA + P+ + +K L + + F +G
Sbjct: 250 VADCICLMALDKPQAVPVDIHVWQIAHRDYGWQPKTSQTKGPSPLANKELGNFFRNLWGP 309
Query: 319 YAGWAQAVLFIAELPSQ 335
YAGWAQAVLF A+L Q
Sbjct: 310 YAGWAQAVLFSADLRQQ 326
>gb|AAB68616.1| 8-hydroxyguanine glycosylase [Mus musculus]
Length = 345
Score = 196 bits (499), Expect = 7e-49
Identities = 118/314 (37%), Positives = 170/314 (53%), Gaps = 12/314 (3%)
Query: 29 RHSTNLSKSRAWIPLNITRQELSLPLTFPTGQTFRWKNTAPSQYTGVVGSHLISLKHLHN 88
RH T S W + R EL L L +GQ+FRWK +P+ ++GV+ + +L +
Sbjct: 12 RHRTLSSSPALWASIPCPRSELRLDLVLASGQSFRWKEQSPAHWSGVLADQVWTLTQTED 71
Query: 89 GDVCYTLHSQS-----PSNDDCKTALLDFLNADVSLADTWKVFSDSDERFAELAQHLSGA 143
C P+ ++ +T L + DVSLA + ++ D F +AQ G
Sbjct: 72 QLYCTVYRGDDSQVSRPTLEELET-LHKYFQLDVSLAQLYSHWASVDSHFQRVAQKFQGV 130
Query: 144 RVLRQDPFECLIQFMCSSNNHISRITKMVDYV-SSLGTYLGCVEGFDFHAFPTLNQLS-L 201
R+LRQDP ECL F+CSSNN+I+RIT MV+ + + G L ++ +H FP L+ L+
Sbjct: 131 RLLRQDPTECLFSFICSSNNNIARITGMVERLCQAFGPRLIQLDDVTYHGFPNLHALAGP 190
Query: 202 VSEQQLRDAGFGYRAKYITGTVNVLQSKPEGGEEWLYSLRKLELEDVISELIKLPGVGPK 261
+E LR G GYRA+Y+ + + + +GG WL LR E L LPGVG K
Sbjct: 191 EAETHLRKLGLGYRARYVRASAKAILEE-QGGPAWLQQLRVAPYEXAHKALCTLPGVGAK 249
Query: 262 VAACIALYSLDQHHAIPVDVHIWRIAQKYI--LPELAGSKLTQKL-HSRVAEAFVTKFGK 318
VA CI L +LD+ A+PVDVH+W+IA + P+ + +K L + + F +G
Sbjct: 250 VADCICLMALDKPQAVPVDVHVWQIAHRDYGWHPKTSQAKGPSPLANKELGNFFRNLWGP 309
Query: 319 YAGWAQAVLFIAEL 332
YAGWAQAVLF A+L
Sbjct: 310 YAGWAQAVLFSADL 323
>pdb|1N39|A Chain A, Structural And Biochemical Exploration Of A Critical Amino
Acid In Human 8-Oxoguanine Glycosylase
gi|46014904|pdb|1M3Q|A Chain A, Crystal Structure Of
Hogg1 D268e Mutant With Base-Excised Dna And
8-Aminoguanine gi|48425055|pdb|1M3H|A Chain A, Crystal
Structure Of Hogg1 D268e Mutant With Product
Oligonucleotide
Length = 317
Score = 196 bits (499), Expect = 7e-49
Identities = 116/313 (37%), Positives = 172/313 (54%), Gaps = 12/313 (3%)
Query: 30 HSTNLSKSRAWIPLNITRQELSLPLTFPTGQTFRWKNTAPSQYTGVVGSHLISLKHLHNG 89
H T S W + R EL L L P+GQ+FRW+ +P+ ++GV+ + +L
Sbjct: 5 HRTLASTPALWASIPCPRSELRLDLVLPSGQSFRWREQSPAHWSGVLADQVWTLTQTEEQ 64
Query: 90 DVCYTLHSQS-----PSNDDCKTALLDFLNADVSLADTWKVFSDSDERFAELAQHLSGAR 144
C P+ D+ + A+ + DV+LA + + D F E+AQ G R
Sbjct: 65 LHCTVYRGDKSQASRPTPDELE-AVRKYFQLDVTLAQLYHHWGSVDSHFQEVAQKFQGVR 123
Query: 145 VLRQDPFECLIQFMCSSNNHISRITKMVDYV-SSLGTYLGCVEGFDFHAFPTLNQLSLVS 203
+LRQDP ECL F+CSSNN+I+RIT MV+ + + G L ++ +H FP+L L+
Sbjct: 124 LLRQDPIECLFSFICSSNNNIARITGMVERLCQAFGPRLIQLDDVTYHGFPSLQALAGPE 183
Query: 204 -EQQLRDAGFGYRAKYITGTVNVLQSKPEGGEEWLYSLRKLELEDVISELIKLPGVGPKV 262
E LR G GYRA+Y++ + + + +GG WL LR+ E+ L LPGVG KV
Sbjct: 184 VEAHLRKLGLGYRARYVSASARAILEE-QGGLAWLQQLRESSYEEAHKALCILPGVGTKV 242
Query: 263 AACIALYSLDQHHAIPVDVHIWRIAQKYIL--PELAGSK-LTQKLHSRVAEAFVTKFGKY 319
A CI L +LD+ A+PV+VH+W IAQ+ P + +K + + + + F + +G Y
Sbjct: 243 ADCICLMALDKPQAVPVEVHMWHIAQRDYSWHPTTSQAKGPSPQTNKELGNFFRSLWGPY 302
Query: 320 AGWAQAVLFIAEL 332
AGWAQAVLF A+L
Sbjct: 303 AGWAQAVLFSADL 315
>pdb|1EBM|A Chain A, Crystal Structure Of The Human 8-Oxoguanine Glycosylase
(Hogg1) Bound To A Substrate Oligonucleotide
Length = 317
Score = 196 bits (499), Expect = 7e-49
Identities = 116/313 (37%), Positives = 172/313 (54%), Gaps = 12/313 (3%)
Query: 30 HSTNLSKSRAWIPLNITRQELSLPLTFPTGQTFRWKNTAPSQYTGVVGSHLISLKHLHNG 89
H T S W + R EL L L P+GQ+FRW+ +P+ ++GV+ + +L
Sbjct: 5 HRTLASTPALWASIPCPRSELRLDLVLPSGQSFRWREQSPAHWSGVLADQVWTLTQTEEQ 64
Query: 90 DVCYTLHSQS-----PSNDDCKTALLDFLNADVSLADTWKVFSDSDERFAELAQHLSGAR 144
C P+ D+ + A+ + DV+LA + + D F E+AQ G R
Sbjct: 65 LHCTVYRGDKSQASRPTPDELE-AVRKYFQLDVTLAQLYHHWGSVDSHFQEVAQKFQGVR 123
Query: 145 VLRQDPFECLIQFMCSSNNHISRITKMVDYV-SSLGTYLGCVEGFDFHAFPTLNQLSLVS 203
+LRQDP ECL F+CSSNN+I+RIT MV+ + + G L ++ +H FP+L L+
Sbjct: 124 LLRQDPIECLFSFICSSNNNIARITGMVERLCQAFGPRLIQLDDVTYHGFPSLQALAGPE 183
Query: 204 -EQQLRDAGFGYRAKYITGTVNVLQSKPEGGEEWLYSLRKLELEDVISELIKLPGVGPKV 262
E LR G GYRA+Y++ + + + +GG WL LR+ E+ L LPGVG +V
Sbjct: 184 VEAHLRKLGLGYRARYVSASARAILEE-QGGLAWLQQLRESSYEEAHKALCILPGVGTQV 242
Query: 263 AACIALYSLDQHHAIPVDVHIWRIAQKYIL--PELAGSK-LTQKLHSRVAEAFVTKFGKY 319
A CI L +LD+ A+PVDVH+W IAQ+ P + +K + + + + F + +G Y
Sbjct: 243 ADCICLMALDKPQAVPVDVHMWHIAQRDYSWHPTTSQAKGPSPQTNKELGNFFRSLWGPY 302
Query: 320 AGWAQAVLFIAEL 332
AGWAQAVLF A+L
Sbjct: 303 AGWAQAVLFSADL 315
>pdb|1N3C|A Chain A, Structural And Biochemical Exploration Of A Critical Amino
Acid In Human 8-Oxoguanine Glycosylase
Length = 317
Score = 196 bits (498), Expect = 9e-49
Identities = 116/313 (37%), Positives = 172/313 (54%), Gaps = 12/313 (3%)
Query: 30 HSTNLSKSRAWIPLNITRQELSLPLTFPTGQTFRWKNTAPSQYTGVVGSHLISLKHLHNG 89
H T S W + R EL L L P+GQ+FRW+ +P+ ++GV+ + +L
Sbjct: 5 HRTLASTPALWASIPCPRSELRLDLVLPSGQSFRWREQSPAHWSGVLADQVWTLTQTEEQ 64
Query: 90 DVCYTLHSQS-----PSNDDCKTALLDFLNADVSLADTWKVFSDSDERFAELAQHLSGAR 144
C P+ D+ + A+ + DV+LA + + D F E+AQ G R
Sbjct: 65 LHCTVYRGDKSQASRPTPDELE-AVRKYFQLDVTLAQLYHHWGSVDSHFQEVAQKFQGVR 123
Query: 145 VLRQDPFECLIQFMCSSNNHISRITKMVDYV-SSLGTYLGCVEGFDFHAFPTLNQLSLVS 203
+LRQDP ECL F+CSSNN+I+RIT MV+ + + G L ++ +H FP+L L+
Sbjct: 124 LLRQDPIECLFSFICSSNNNIARITGMVERLCQAFGPRLIQLDDVTYHGFPSLQALAGPE 183
Query: 204 -EQQLRDAGFGYRAKYITGTVNVLQSKPEGGEEWLYSLRKLELEDVISELIKLPGVGPKV 262
E LR G GYRA+Y++ + + + +GG WL LR+ E+ L LPGVG KV
Sbjct: 184 VEAHLRKLGLGYRARYVSASARAILEE-QGGLAWLQQLRESSYEEAHKALCILPGVGTKV 242
Query: 263 AACIALYSLDQHHAIPVDVHIWRIAQKYIL--PELAGSK-LTQKLHSRVAEAFVTKFGKY 319
A CI L +LD+ A+PV+VH+W IAQ+ P + +K + + + + F + +G Y
Sbjct: 243 ADCICLMALDKPQAVPVNVHMWHIAQRDYSWHPTTSQAKGPSPQTNKELGNFFRSLWGPY 302
Query: 320 AGWAQAVLFIAEL 332
AGWAQAVLF A+L
Sbjct: 303 AGWAQAVLFSADL 315
>pdb|1N3A|A Chain A, Structural And Biochemical Exploration Of A Critical Amino
Acid In Human 8-Oxoguanine Glycosylase
Length = 317
Score = 196 bits (497), Expect = 1e-48
Identities = 116/313 (37%), Positives = 171/313 (54%), Gaps = 12/313 (3%)
Query: 30 HSTNLSKSRAWIPLNITRQELSLPLTFPTGQTFRWKNTAPSQYTGVVGSHLISLKHLHNG 89
H T S W + R EL L L P+GQ+FRW+ +P+ ++GV+ + +L
Sbjct: 5 HRTLASTPALWASIPCPRSELRLDLVLPSGQSFRWREQSPAHWSGVLADQVWTLTQTEEQ 64
Query: 90 DVCYTLHSQS-----PSNDDCKTALLDFLNADVSLADTWKVFSDSDERFAELAQHLSGAR 144
C P+ D+ + A+ + DV+LA + + D F E+AQ G R
Sbjct: 65 LHCTVYRGDKSQASRPTPDELE-AVRKYFQLDVTLAQLYHHWGSVDSHFQEVAQKFQGVR 123
Query: 145 VLRQDPFECLIQFMCSSNNHISRITKMVDYV-SSLGTYLGCVEGFDFHAFPTLNQLSLVS 203
+LRQDP ECL F+CSSNN+I+RIT MV+ + + G L ++ +H FP+L L+
Sbjct: 124 LLRQDPIECLFSFICSSNNNIARITGMVERLCQAFGPRLIQLDDVTYHGFPSLQALAGPE 183
Query: 204 -EQQLRDAGFGYRAKYITGTVNVLQSKPEGGEEWLYSLRKLELEDVISELIKLPGVGPKV 262
E LR G GYRA+Y++ + + + +GG WL LR+ E+ L LPGVG KV
Sbjct: 184 VEAHLRKLGLGYRARYVSASARAILEE-QGGLAWLQQLRESSYEEAHKALCILPGVGTKV 242
Query: 263 AACIALYSLDQHHAIPVDVHIWRIAQKYIL--PELAGSK-LTQKLHSRVAEAFVTKFGKY 319
A CI L +LD+ A+PV VH+W IAQ+ P + +K + + + + F + +G Y
Sbjct: 243 ADCICLMALDKPQAVPVQVHMWHIAQRDYSWHPTTSQAKGPSPQTNKELGNFFRSLWGPY 302
Query: 320 AGWAQAVLFIAEL 332
AGWAQAVLF A+L
Sbjct: 303 AGWAQAVLFSADL 315
>gb|AAB61289.1| 8-oxoguanine DNA glycosylase 1; mOgg1 [Mus musculus]
Length = 345
Score = 195 bits (496), Expect = 2e-48
Identities = 118/317 (37%), Positives = 173/317 (54%), Gaps = 12/317 (3%)
Query: 26 TQTRHSTNLSKSRAWIPLNITRQELSLPLTFPTGQTFRWKNTAPSQYTGVVGSHLISLKH 85
+Q RH T S + + R EL L L +GQ+FRWK +P+ ++GV+ + +L
Sbjct: 9 SQMRHRTLSSSPALSVAIPCPRSELRLDLVLASGQSFRWKEQSPAHWSGVLADQVWTLTQ 68
Query: 86 LHNGDVCYTLHSQS-----PSNDDCKTALLDFLNADVSLADTWKVFSDSDERFAELAQHL 140
+ C P+ ++ +T L + DVSLA + ++ D F +AQ
Sbjct: 69 TEDQLYCTVYRGDDSQVSRPTLEELET-LHKYFQLDVSLAQLYSHWASVDSHFQRVAQKF 127
Query: 141 SGARVLRQDPFECLIQFMCSSNNHISRITKMVDYV-SSLGTYLGCVEGFDFHAFPTLNQL 199
G R+LRQDP ECL F+CSSNN+I+RIT MV+ + + G L ++ +H FP L+ L
Sbjct: 128 QGVRLLRQDPTECLFSFICSSNNNIARITGMVERLCQAFGPRLIQLDDVTYHGFPNLHAL 187
Query: 200 S-LVSEQQLRDAGFGYRAKYITGTVNVLQSKPEGGEEWLYSLRKLELEDVISELIKLPGV 258
+ +E LR G GYRA+Y+ + + + +GG WL LR E+ L LPGV
Sbjct: 188 AGPEAETHLRKLGLGYRARYVRASAKAILEE-QGGPAWLQQLRVAPYEEAHKGLCTLPGV 246
Query: 259 GPKVAACIALYSLDQHHAIPVDVHIWRIAQKYI--LPELAGSKLTQKL-HSRVAEAFVTK 315
G KVA CI L +LD+ A+PVDVH+W+IA + P+ + +K L + + F
Sbjct: 247 GAKVADCICLMALDKPQAVPVDVHVWQIAHRDYGWHPKTSQAKGPSPLANKELGNFFRNL 306
Query: 316 FGKYAGWAQAVLFIAEL 332
+G YAGWAQAVLF A+L
Sbjct: 307 WGPYAGWAQAVLFSADL 323
>pdb|1YQK|A Chain A, Human 8-Oxoguanine Glycosylase Crosslinked With Guanine
Containing Dna
Length = 319
Score = 194 bits (494), Expect = 3e-48
Identities = 116/313 (37%), Positives = 171/313 (54%), Gaps = 12/313 (3%)
Query: 30 HSTNLSKSRAWIPLNITRQELSLPLTFPTGQTFRWKNTAPSQYTGVVGSHLISLKHLHNG 89
H T S W + R EL L L P+GQ+FRW+ +P+ ++GV+ + +L
Sbjct: 5 HRTLASTPALWASIPCPRSELRLDLVLPSGQSFRWREQSPAHWSGVLADQVWTLTQTEEQ 64
Query: 90 DVCYTLHSQS-----PSNDDCKTALLDFLNADVSLADTWKVFSDSDERFAELAQHLSGAR 144
C P+ D+ + A+ + DV+LA + + D F E+AQ G R
Sbjct: 65 LHCTVYRGDKSQASRPTPDELE-AVRKYFQLDVTLAQLYHHWGSVDSHFQEVAQKFQGVR 123
Query: 145 VLRQDPFECLIQFMCSSNNHISRITKMVDYV-SSLGTYLGCVEGFDFHAFPTLNQLSLVS 203
+LRQDP ECL F+CSS N+I+RIT MV+ + + G L ++ +H FP+L L+
Sbjct: 124 LLRQDPIECLFSFICSSCNNIARITGMVERLCQAFGPRLIQLDDVTYHGFPSLQALAGPE 183
Query: 204 -EQQLRDAGFGYRAKYITGTVNVLQSKPEGGEEWLYSLRKLELEDVISELIKLPGVGPKV 262
E LR G GYRA+Y++ + + + +GG WL LR+ E+ L LPGVG KV
Sbjct: 184 VEAHLRKLGLGYRARYVSASARAILEE-QGGLAWLQQLRESSYEEAHKALCILPGVGTKV 242
Query: 263 AACIALYSLDQHHAIPVDVHIWRIAQKYIL--PELAGSK-LTQKLHSRVAEAFVTKFGKY 319
A CI L +LD+ A+PVDVH+W IAQ+ P + +K + + + + F + +G Y
Sbjct: 243 ADCICLMALDKPQAVPVDVHMWHIAQRDYSWHPTTSQAKGPSPQTNKELGNFFRSLWGPY 302
Query: 320 AGWAQAVLFIAEL 332
AGWAQAVLF A+L
Sbjct: 303 AGWAQAVLFSADL 315
Database: nr
Posted date: Jul 5, 2005 12:34 AM
Number of letters in database: 863,360,394
Number of sequences in database: 2,540,612
Lambda K H
0.318 0.133 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 649,507,205
Number of Sequences: 2540612
Number of extensions: 27579690
Number of successful extensions: 133637
Number of sequences better than 10.0: 269
Number of HSP's better than 10.0 without gapping: 146
Number of HSP's successfully gapped in prelim test: 125
Number of HSP's that attempted gapping in prelim test: 132984
Number of HSP's gapped (non-prelim): 395
length of query: 363
length of database: 863,360,394
effective HSP length: 129
effective length of query: 234
effective length of database: 535,621,446
effective search space: 125335418364
effective search space used: 125335418364
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 76 (33.9 bits)
Medicago: description of AC140916.11